locus-tag	class	description
YPC_0001	COG0716	FMN binding
YPC_0002	COG1522	sequence-specific DNA binding
YPC_0008	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPC_0010	COG0477	Major facilitator Superfamily
YPC_0011	COG2186	Transcriptional regulator
YPC_0021	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPC_0022	COG2224	Isocitrate lyase
YPC_0032	COG0527	aspartate kinase activity
YPC_0035	COG3833	ABC-type maltose transport systems, permease component
YPC_0036	COG1175	transmembrane transport
YPC_0052	COG2801	Transposase and inactivated derivatives
YPC_0054	COG1349	DNA-binding transcription factor activity
YPC_0060	COG1640	4-alpha-glucanotransferase
YPC_0068	COG1918	ferrous iron import across plasma membrane
YPC_0070	COG2183	response to ionizing radiation
YPC_0071	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPC_0072	COG0745	RESPONSE REGULATOR receiver
YPC_0076	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPC_0077	COG1011	Hydrolase
YPC_0079	COG0494	nUDIX hydrolase
YPC_0080	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YPC_0086	COG4796	Type ii and iii secretion system protein
YPC_0091	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPC_0092	COG0546	phosphoglycolate phosphatase activity
YPC_0093	COG0180	Tryptophanyl-tRNA synthetase
YPC_0097	COG2146	nitrite reductase [NAD(P)H] activity
YPC_0098	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPC_0100	COG0402	S-adenosylhomocysteine deaminase activity
YPC_0104	COG1486	melibiose metabolic process
YPC_0105	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPC_0106	COG0433	COG0433 Predicted ATPase
YPC_0110	COG1289	transmembrane transporter activity
YPC_0112	COG1765	OsmC-like protein
YPC_0114	COG3954	Phosphoribulokinase
YPC_0116	COG0429	hydrolase of the alpha beta-hydrolase fold
YPC_0119	COG4521	taurine ABC transporter
YPC_0121	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPC_0122	COG2175	clavaminate synthase activity
YPC_0124	COG1216	Glycosyl transferase, family 2
YPC_0129	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YPC_0130	COG1047	Peptidyl-prolyl cis-trans
YPC_0133	COG0545	Peptidyl-prolyl cis-trans isomerase
YPC_0134	COG2964	Protein conserved in bacteria
YPC_0138	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YPC_0139	COG0049	tRNA binding
YPC_0144	COG1943	Transposase
YPC_0147	COG0051	transcription antitermination factor activity, RNA binding
YPC_0152	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YPC_0154	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YPC_0155	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YPC_0157	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YPC_0158	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPC_0166	COG1841	ribosomal large subunit assembly
YPC_0168	COG0201	protein transport
YPC_0169	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPC_0172	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPC_0175	COG0789	Transcriptional regulator
YPC_0176	COG3036	rescue of stalled ribosome
YPC_0178	COG0569	domain protein
YPC_0182	COG0758	DNA mediated transformation
YPC_0184	COG0551	DNA topoisomerase type I activity
YPC_0187	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPC_0190	COG0456	acetyltransferase
YPC_0191	COG2982	Protein involved in outer membrane biogenesis
YPC_0193	COG2233	PERMEase
YPC_0194	COG0786	glutamate:sodium symporter activity
YPC_0196	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPC_0197	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPC_0198	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPC_0201	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YPC_0202	COG2860	membrane
YPC_0203	COG1561	YicC-like family, N-terminal region
YPC_0208	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YPC_0211	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YPC_0215	COG1519	Transferase
YPC_0216	COG0859	PFAM glycosyl transferase family 9
YPC_0217	COG0859	PFAM glycosyl transferase family 9
YPC_0219	COG0156	8-amino-7-oxononanoate synthase activity
YPC_0223	COG4942	peptidase
YPC_0225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPC_0226	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPC_0230	COG1045	serine acetyltransferase
YPC_0231	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPC_0232	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPC_0232	COG2169	Transcriptional regulator
YPC_0233	COG2205	protein histidine kinase activity
YPC_0234	COG0745	RESPONSE REGULATOR receiver
YPC_0235	COG3678	ATP-independent chaperone mediated protein folding
YPC_0241	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPC_0243	COG0471	metal ion transport
YPC_0244	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPC_0245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPC_0246	COG0583	DNA-binding transcription factor activity
YPC_0249	COG3152	Membrane
YPC_0251	COG1494	fructose-1,6-bisphosphatase
YPC_0252	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPC_0268	COG1575	Belongs to the MenA family. Type 1 subfamily
YPC_0271	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPC_0272	COG1609	Transcriptional regulator
YPC_0273	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPC_0276	COG4682	membrane
YPC_0280	COG0626	cystathionine gamma-synthase activity
YPC_0281	COG0626	cystathionine gamma-synthase activity
YPC_0282	COG0460	homoserine dehydrogenase
YPC_0282	COG0527	aspartate kinase activity
YPC_0284	COG2801	Transposase and inactivated derivatives
YPC_0289	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
YPC_0298	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPC_0299	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPC_0299	COG0678	peroxiredoxin activity
YPC_0315	COG1879	ABC-type sugar transport system periplasmic component
YPC_0316	COG1129	ABC transporter
YPC_0320	COG3085	chromosome segregation
YPC_0323	COG3978	acetolactate synthase activity
YPC_0324	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPC_0332	COG0583	DNA-binding transcription factor activity
YPC_0340	COG3121	Chaperone
YPC_0343	COG3121	Chaperone
YPC_0345	COG3328	transposase activity
YPC_0347	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPC_0354	COG3118	belongs to the thioredoxin family
YPC_0355	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPC_0356	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YPC_0357	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPC_0358	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPC_0359	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPC_0360	COG1088	dTDP-glucose 4,6-dehydratase activity
YPC_0361	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPC_0362	COG0456	acetyltransferase
YPC_0363	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPC_0364	COG2244	polysaccharide biosynthetic process
YPC_0368	COG1113	amino acid transport
YPC_0376	COG3071	HemY protein
YPC_0377	COG2959	enzyme of heme biosynthesis
YPC_0378	COG1587	Uroporphyrinogen-III synthase
YPC_0382	COG3072	Adenylate cyclase
YPC_0385	COG5567	small periplasmic lipoprotein
YPC_0387	COG3159	Protein conserved in bacteria
YPC_0388	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPC_0389	COG1011	Hydrolase
YPC_0390	COG0210	DNA helicase
YPC_0392	COG5441	Belongs to the UPF0261 family
YPC_0393	COG5564	TIM-barrel signal transduction protein
YPC_0395	COG0598	Magnesium transport protein CorA
YPC_0397	COG2050	protein possibly involved in aromatic compounds catabolism
YPC_0400	COG0514	ATP-dependent DNA helicase (RecQ)
YPC_0401	COG1280	lysine exporter protein (LysE YggA)
YPC_0402	COG1280	lysine exporter protein (LysE YggA)
YPC_0403	COG2267	carboxylic ester hydrolase activity
YPC_0404	COG0561	phosphatase activity
YPC_0406	COG0584	glycerophosphoryl diester phosphodiesterase
YPC_0412	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPC_0416	COG3714	YhhN family
YPC_0419	COG3776	membrane
YPC_0420	COG0742	ribosomal rna small subunit methyltransferase
YPC_0421	COG0552	protein localization to endoplasmic reticulum
YPC_0421	COG0552	protein localization to endoplasmic reticulum
YPC_0422	COG2884	Cell division ATP-binding protein ftsE
YPC_0423	COG2177	Part of the ABC transporter FtsEX involved in
YPC_0427	COG1943	Transposase
YPC_0430	COG0683	leucine binding
YPC_0431	COG0559	Belongs to the binding-protein-dependent transport system permease family
YPC_0432	COG4177	L-phenylalanine transmembrane transporter activity
YPC_0433	COG0411	ABC transporter
YPC_0434	COG0410	ABC transporter
YPC_0447	COG0584	glycerophosphoryl diester phosphodiesterase
YPC_0448	COG0679	Auxin Efflux Carrier
YPC_0450	COG0583	DNA-binding transcription factor activity
YPC_0452	COG0412	Dienelactone hydrolase
YPC_0453	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
YPC_0455	COG1966	Carbon starvation protein
YPC_0456	COG0586	Pfam SNARE associated Golgi protein
YPC_0457	COG1322	Protein conserved in bacteria
YPC_0461	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPC_0463	COG0805	protein transport
YPC_0476	COG1739	Uncharacterized protein family UPF0029
YPC_0478	COG1739	Uncharacterized protein family UPF0029
YPC_0479	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPC_0480	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YPC_0499	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPC_0500	COG0250	Participates in transcription elongation, termination and antitermination
YPC_0507	COG1943	Transposase
YPC_0514	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YPC_0519	COG1515	deoxyribonuclease V activity
YPC_0520	COG3068	Protein conserved in bacteria
YPC_0524	COG0151	Belongs to the GarS family
YPC_0533	COG2801	Transposase and inactivated derivatives
YPC_0537	COG4771	TonB-dependent receptor
YPC_0538	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPC_0539	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YPC_0550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPC_0553	COG3300	MHYT domain
YPC_0553	COG5001	Diguanylate cyclase
YPC_0554	COG2801	Transposase and inactivated derivatives
YPC_0560	COG0195	Participates in both transcription termination and antitermination
YPC_0564	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPC_0566	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPC_0567	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YPC_0569	COG1534	Rna-binding protein
YPC_0571	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPC_0572	COG2027	D-alanyl-D-alanine carboxypeptidase
YPC_0573	COG0745	RESPONSE REGULATOR receiver
YPC_0574	COG0642	Histidine kinase
YPC_0576	COG0697	spore germination
YPC_0579	COG0142	geranyltranstransferase activity
YPC_0581	COG3423	Transcriptional regulator
YPC_0586	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPC_0588	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPC_0589	COG2105	PFAM AIG2 family protein
YPC_0592	COG0729	surface antigen
YPC_0594	COG1253	flavin adenine dinucleotide binding
YPC_0596	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPC_0598	COG0737	Belongs to the 5'-nucleotidase family
YPC_0600	COG0545	Peptidyl-prolyl cis-trans isomerase
YPC_0601	COG3061	Opacity-associated protein A
YPC_0603	COG1943	Transposase
YPC_0606	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YPC_0608	COG0360	Binds together with S18 to 16S ribosomal RNA
YPC_0610	COG1073	alpha beta
YPC_0614	COG3650	response to hydrogen peroxide
YPC_0615	COG1960	acyl-CoA dehydrogenase activity
YPC_0617	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPC_0619	COG0557	exoribonuclease II activity
YPC_0622	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YPC_0623	COG0330	HflC and HflK could
YPC_0624	COG0330	HflC and HflK could
YPC_0625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPC_0629	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPC_0630	COG0802	atpase or kinase
YPC_0631	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YPC_0631	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YPC_0632	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPC_0636	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
YPC_0639	COG3264	Mechanosensitive ion channel
YPC_0639	COG1511	domain protein
YPC_0642	COG1053	succinate dehydrogenase
YPC_0643	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPC_0645	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPC_0646	COG2076	Multidrug Resistance protein
YPC_0655	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPC_0658	COG3383	formate dehydrogenase (NAD+) activity
YPC_0659	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPC_0660	COG0493	'glutamate synthase
YPC_0660	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPC_0661	COG1309	transcriptional regulator
YPC_0677	COG1454	alcohol dehydrogenase
YPC_0679	COG0629	single-stranded DNA binding
YPC_0680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPC_0681	COG2315	Protein conserved in bacteria
YPC_0682	COG1448	Aminotransferase
YPC_0683	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPC_0684	COG0305	Participates in initiation and elongation during chromosome replication
YPC_0688	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPC_0689	COG0735	belongs to the Fur family
YPC_0691	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPC_0702	COG3121	Chaperone
YPC_0714	COG1358	cellular component organization or biogenesis
YPC_0719	COG3721	Heme iron utilization protein
YPC_0720	COG0702	epimerase
YPC_0723	COG4771	TonB-dependent receptor
YPC_0724	COG3720	iron ion transport
YPC_0725	COG4558	Periplasmic binding protein
YPC_0726	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPC_0728	COG0626	cystathionine gamma-synthase activity
YPC_0729	COG0814	amino acid
YPC_0730	COG0583	DNA-binding transcription factor activity
YPC_0731	COG0425	Belongs to the sulfur carrier protein TusA family
YPC_0732	COG2391	methyltransferase activity
YPC_0756	COG1301	dicarboxylic acid transport
YPC_0758	COG3162	membrane
YPC_0763	COG2226	methyltransferase
YPC_0763	COG3433	isochorismatase activity
YPC_0763	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPC_0764	COG3433	isochorismatase activity
YPC_0764	COG2226	methyltransferase
YPC_0764	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPC_0765	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPC_0767	COG3433	isochorismatase activity
YPC_0767	COG2226	methyltransferase
YPC_0767	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPC_0775	COG1132	(ABC) transporter
YPC_0779	COG2610	gluconate transmembrane transporter activity
YPC_0785	COG3501	Rhs element vgr protein
YPC_0787	COG3209	COG3209 Rhs family protein
YPC_0792	COG0471	metal ion transport
YPC_0795	COG2801	Transposase and inactivated derivatives
YPC_0797	COG2211	Major facilitator Superfamily
YPC_0810	COG2771	luxR family
YPC_0811	COG3916	Acyl-homoserine-lactone synthase
YPC_0834	COG1662	PFAM IS1 transposase
YPC_0839	COG1982	Orn Lys Arg decarboxylase major
YPC_0840	COG1879	ABC-type sugar transport system periplasmic component
YPC_0841	COG1129	ABC transporter
YPC_0842	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_0843	COG4774	siderophore transport
YPC_0847	COG1194	a g-specific adenine glycosylase
YPC_0849	COG3171	Protein conserved in bacteria
YPC_0850	COG2066	Belongs to the glutaminase family
YPC_0853	COG3064	Membrane
YPC_0853	COG1073	alpha beta
YPC_0853	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPC_0854	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPC_0855	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YPC_0857	COG0762	integral membrane protein
YPC_0858	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPC_0859	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPC_0860	COG2805	Type II/IV secretion system protein
YPC_0862	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPC_0865	COG0189	ligase activity
YPC_0866	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPC_0869	COG2356	endonuclease I
YPC_0873	COG1166	arginine decarboxylase activity
YPC_0876	COG0501	Belongs to the peptidase M48B family
YPC_0877	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPC_0882	COG0191	fructose-bisphosphate aldolase activity
YPC_0888	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YPC_0889	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPC_0891	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPC_0895	COG0006	proline dipeptidase activity
YPC_0896	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPC_0897	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPC_0905	COG5295	Hep Hag repeat protein
YPC_0907	COG1272	protein, Hemolysin III
YPC_0910	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
YPC_0912	COG0745	RESPONSE REGULATOR receiver
YPC_0913	COG2205	protein histidine kinase activity
YPC_0914	COG4452	Inner membrane protein CreD
YPC_0915	COG0716	FMN binding
YPC_0916	COG4974	Belongs to the 'phage' integrase family
YPC_0917	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPC_0918	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPC_0922	COG0582	viral genome integration into host DNA
YPC_0928	COG2944	sequence-specific DNA binding
YPC_0948	COG1695	Transcriptional regulator
YPC_0951	COG0791	NLP P60 protein
YPC_0953	COG1879	ABC-type sugar transport system periplasmic component
YPC_0954	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_0955	COG1129	ABC transporter
YPC_0957	COG2182	Extracellular solute-binding protein
YPC_0958	COG1175	transmembrane transport
YPC_0959	COG3833	ABC-type maltose transport systems, permease component
YPC_0960	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPC_0961	COG1874	Beta-galactosidase
YPC_0962	COG1263	PTS System
YPC_0962	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPC_0973	COG0191	fructose-bisphosphate aldolase activity
YPC_0976	COG3119	arylsulfatase activity
YPC_0977	COG0641	radical SAM
YPC_0982	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPC_0985	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPC_0986	COG2222	sugar isomerase
YPC_0988	COG1349	DNA-binding transcription factor activity
YPC_0991	COG3119	arylsulfatase activity
YPC_0992	COG1943	Transposase
YPC_1002	COG0288	reversible hydration of carbon dioxide
YPC_1011	COG2165	general secretion pathway protein
YPC_1021	COG0840	transmembrane signaling receptor activity
YPC_1024	COG0583	DNA-binding transcription factor activity
YPC_1025	COG2814	Major facilitator Superfamily
YPC_1026	COG0583	DNA-binding transcription factor activity
YPC_1027	COG0019	diaminopimelate decarboxylase activity
YPC_1028	COG1609	Transcriptional regulator
YPC_1037	COG0667	Aldo Keto reductase
YPC_1049	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPC_1054	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPC_1057	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPC_1058	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPC_1059	COG2166	iron-sulfur cluster assembly
YPC_1060	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPC_1063	COG0583	DNA-binding transcription factor activity
YPC_1064	COG2363	Small membrane protein
YPC_1066	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPC_1067	COG1611	Belongs to the LOG family
YPC_1071	COG1943	Transposase
YPC_1072	COG3098	single-species biofilm formation
YPC_1073	COG0564	pseudouridine synthase activity
YPC_1081	COG0024	Methionine aminopeptidase
YPC_1088	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YPC_1089	COG0575	Belongs to the CDS family
YPC_1090	COG0750	zinc metalloprotease
YPC_1092	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
YPC_1096	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPC_1098	COG0587	DNA-directed DNA polymerase activity
YPC_1100	COG0346	lactoylglutathione lyase activity
YPC_1101	COG0037	tRNA processing
YPC_1103	COG4568	rho-dependent transcription termination
YPC_1105	COG4681	YaeQ
YPC_1107	COG3015	lipoprotein NlpE involved in copper resistance
YPC_1109	COG1720	tRNA m6t6A37 methyltransferase activity
YPC_1111	COG1464	Belongs to the NlpA lipoprotein family
YPC_1112	COG2011	ABC-type metal ion transport system permease component
YPC_1114	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPC_1121	COG0656	L-ascorbic acid biosynthetic process
YPC_1124	COG0741	lytic transglycosylase activity
YPC_1124	COG1388	LysM domain
YPC_1126	COG2226	methyltransferase
YPC_1128	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YPC_1130	COG1953	Uracil, thiamine, allantoin
YPC_1136	COG3657	addiction module killer protein
YPC_1149	COG0582	viral genome integration into host DNA
YPC_1155	COG2867	negative regulation of translational initiation
YPC_1157	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPC_1158	COG0497	DNA recombination
YPC_1159	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YPC_1163	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPC_1164	COG1053	succinate dehydrogenase
YPC_1166	COG0567	Dehydrogenase, E1 component
YPC_1167	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPC_1169	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPC_1170	COG1271	oxidase subunit
YPC_1171	COG1294	oxidase, subunit
YPC_1172	COG4890	Cyd operon protein YbgT
YPC_1173	COG3790	cyd operon protein YbgE
YPC_1174	COG0824	Thioesterase
YPC_1175	COG0811	peptide transport
YPC_1176	COG0848	biopolymer transport protein
YPC_1177	COG3064	Membrane
YPC_1177	COG3064	Membrane
YPC_1179	COG2885	chlorophyll binding
YPC_1180	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPC_1186	COG1230	cation diffusion facilitator family transporter
YPC_1187	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPC_1190	COG2017	converts alpha-aldose to the beta-anomer
YPC_1193	COG1085	galactose-1-phosphate uridylyltransferase
YPC_1194	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YPC_1197	COG1119	ATPase activity
YPC_1198	COG2005	Transcriptional regulator
YPC_1198	COG3585	molybdate ion transport
YPC_1201	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPC_1202	COG4149	molybdate abc transporter
YPC_1204	COG0561	phosphatase activity
YPC_1209	COG2226	methyltransferase
YPC_1210	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPC_1212	COG0556	nucleotide-excision repair
YPC_1214	COG4628	conserved protein (DUF2132)
YPC_1215	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPC_1216	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPC_1218	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YPC_1219	COG0314	molybdopterin synthase activity
YPC_1220	COG0670	Belongs to the BI1 family
YPC_1223	COG1943	Transposase
YPC_1228	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPC_1230	COG0583	DNA-binding transcription factor activity
YPC_1232	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPC_1239	COG1902	pentaerythritol trinitrate reductase activity
YPC_1244	COG0842	Transport permease protein
YPC_1245	COG0842	Transport permease protein
YPC_1246	COG1131	(ABC) transporter
YPC_1248	COG1309	transcriptional regulator
YPC_1249	COG0513	Belongs to the DEAD box helicase family
YPC_1258	COG3328	transposase activity
YPC_1261	COG0351	phosphomethylpyrimidine kinase
YPC_1268	COG3422	double-strand break repair
YPC_1269	COG0745	RESPONSE REGULATOR receiver
YPC_1270	COG2205	protein histidine kinase activity
YPC_1275	COG3842	ATPase activity
YPC_1277	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPC_1279	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPC_1280	COG1177	transmembrane transport
YPC_1281	COG0443	Heat shock 70 kDa protein
YPC_1282	COG2239	Acts as a magnesium transporter
YPC_1284	COG0248	Ppx GppA phosphatase
YPC_1285	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPC_1293	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPC_1294	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPC_1298	COG1943	Transposase
YPC_1300	COG1393	Belongs to the ArsC family
YPC_1301	COG4783	chaperone-mediated protein folding
YPC_1302	COG0628	permease
YPC_1307	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPC_1308	COG2716	regulation of RNA biosynthetic process
YPC_1310	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPC_1312	COG1943	Transposase
YPC_1314	COG2321	neutral zinc metallopeptidase
YPC_1318	COG1876	peptidase activity
YPC_1320	COG1393	Belongs to the ArsC family
YPC_1323	COG1840	ABC-type Fe3 transport system, periplasmic component
YPC_1324	COG1175	transmembrane transport
YPC_1325	COG3842	ATPase activity
YPC_1326	COG3119	arylsulfatase activity
YPC_1327	COG0641	radical SAM
YPC_1329	COG1988	membrane-bound metal-dependent
YPC_1333	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPC_1336	COG2197	response regulator
YPC_1337	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPC_1337	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPC_1338	COG3062	negative regulation of establishment of protein localization
YPC_1341	COG3043	anaerobic respiration
YPC_1342	COG3005	denitrification pathway
YPC_1352	COG3111	PFAM Bacterial OB fold (BOF) protein
YPC_1354	COG2837	iron assimilation
YPC_1355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPC_1357	COG4886	Leucine-rich repeat (LRR) protein
YPC_1359	COG2731	YhcH YjgK YiaL family protein
YPC_1361	COG1737	Transcriptional regulator
YPC_1363	COG4150	thiosulfate binding
YPC_1364	COG4150	thiosulfate binding
YPC_1365	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPC_1366	COG4208	sulfate ABC transporter
YPC_1367	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
YPC_1370	COG0745	RESPONSE REGULATOR receiver
YPC_1371	COG5002	protein histidine kinase activity
YPC_1371	COG3850	Histidine kinase
YPC_1374	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPC_1376	COG0006	proline dipeptidase activity
YPC_1378	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPC_1381	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPC_1382	COG0745	RESPONSE REGULATOR receiver
YPC_1383	COG2205	protein histidine kinase activity
YPC_1390	COG2190	(PTS) system
YPC_1392	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPC_1393	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YPC_1394	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YPC_1397	COG3530	Putative quorum-sensing-regulated virulence factor
YPC_1403	COG1943	Transposase
YPC_1409	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPC_1414	COG0667	Aldo Keto reductase
YPC_1420	COG0436	Aminotransferase
YPC_1421	COG3038	cytochrome b561
YPC_1428	COG3381	protein complex oligomerization
YPC_1429	COG3302	dmso reductase anchor subunit
YPC_1430	COG0437	4 iron, 4 sulfur cluster binding
YPC_1431	COG0243	molybdopterin cofactor binding
YPC_1440	COG2951	lytic endotransglycosylase activity
YPC_1454	COG3121	Chaperone
YPC_1455	COG3188	usher protein
YPC_1456	COG3328	transposase activity
YPC_1457	COG3188	usher protein
YPC_1471	COG3501	Rhs element vgr protein
YPC_1477	COG2824	Alkylphosphonate utilization operon protein PhnA
YPC_1480	COG1704	LemA family
YPC_1486	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPC_1487	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPC_1488	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPC_1491	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPC_1496	COG3691	Protein conserved in bacteria
YPC_1499	COG2062	phosphohistidine phosphatase, SixA
YPC_1501	COG2890	protein-(glutamine-N5) methyltransferase activity
YPC_1504	COG0730	response to heat
YPC_1506	COG3101	peptidyl-lysine hydroxylation
YPC_1509	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPC_1511	COG1794	racemase activity, acting on amino acids and derivatives
YPC_1515	COG0697	spore germination
YPC_1518	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPC_1520	COG0586	Pfam SNARE associated Golgi protein
YPC_1522	COG0285	dihydrofolate synthase activity
YPC_1523	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPC_1524	COG1286	toxin biosynthetic process
YPC_1525	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPC_1526	COG0163	prenyltransferase activity
YPC_1529	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPC_1530	COG4215	(ABC) transporter
YPC_1531	COG4160	amino acid transport
YPC_1532	COG4598	ABC transporter
YPC_1533	COG1090	epimerase
YPC_1535	COG0622	Phosphoesterase
YPC_1537	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YPC_1538	COG3037	sugar-specific permease SgaT UlaA
YPC_1539	COG3328	transposase activity
YPC_1543	COG1609	Transcriptional regulator
YPC_1545	COG0857	belongs to the CobB CobQ family
YPC_1545	COG0280	phosphate acetyltransferase
YPC_1551	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPC_1552	COG0490	domain, Protein
YPC_1552	COG0471	metal ion transport
YPC_1556	COG0436	Aminotransferase
YPC_1558	COG0583	DNA-binding transcription factor activity
YPC_1561	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPC_1563	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
YPC_1565	COG1034	ATP synthesis coupled electron transport
YPC_1568	COG0839	Belongs to the complex I subunit 6 family
YPC_1570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPC_1571	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPC_1574	COG2731	YhcH YjgK YiaL family protein
YPC_1575	COG3265	gluconokinase activity
YPC_1576	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_1580	COG1609	Transcriptional regulator
YPC_1582	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPC_1586	COG0129	dihydroxy-acid dehydratase activity
YPC_1590	COG4575	ribosome binding
YPC_1593	COG1169	isochorismate synthase
YPC_1596	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPC_1599	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPC_1609	COG1126	abc transporter atp-binding protein
YPC_1610	COG0765	amino acid transport
YPC_1611	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPC_1619	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPC_1623	COG1063	alcohol dehydrogenase
YPC_1624	COG1879	ABC-type sugar transport system periplasmic component
YPC_1625	COG1129	ABC transporter
YPC_1626	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_1627	COG1609	Transcriptional regulator
YPC_1628	COG0583	DNA-binding transcription factor activity
YPC_1629	COG0473	3-isopropylmalate dehydrogenase activity
YPC_1631	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPC_1634	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPC_1635	COG2831	hemolysin activation secretion protein
YPC_1636	COG3210	domain, Protein
YPC_1637	COG3210	domain, Protein
YPC_1640	COG3210	domain, Protein
YPC_1645	COG3210	domain, Protein
YPC_1646	COG3210	domain, Protein
YPC_1648	COG3842	ATPase activity
YPC_1650	COG1609	Transcriptional regulator
YPC_1653	COG0395	ABC-type sugar transport system, permease component
YPC_1654	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPC_1658	COG0668	transmembrane transport
YPC_1659	COG1518	maintenance of DNA repeat elements
YPC_1660	COG1203	CRISPR-associated helicase, Cas3
YPC_1665	COG0667	Aldo Keto reductase
YPC_1668	COG0477	Major facilitator Superfamily
YPC_1669	COG0583	DNA-binding transcription factor activity
YPC_1670	COG2771	luxR family
YPC_1671	COG3916	Acyl-homoserine-lactone synthase
YPC_1678	COG0628	permease
YPC_1682	COG3328	transposase activity
YPC_1686	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YPC_1687	COG3328	transposase activity
YPC_1688	COG1530	ribonuclease E activity
YPC_1689	COG0564	pseudouridine synthase activity
YPC_1691	COG1399	metal-binding, possibly nucleic acid-binding protein
YPC_1692	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YPC_1696	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_1698	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPC_1701	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPC_1703	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPC_1705	COG0470	DNA polymerase III
YPC_1706	COG0084	hydrolase, TatD family'
YPC_1707	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPC_1707	COG1263	PTS System
YPC_1710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPC_1711	COG0537	adenosine 5'-monophosphoramidase activity
YPC_1712	COG5633	Lipoprotein
YPC_1715	COG1472	Belongs to the glycosyl hydrolase 3 family
YPC_1717	COG1252	NADH dehydrogenase
YPC_1722	COG3328	transposase activity
YPC_1723	COG3134	Outer membrane lipoprotein
YPC_1724	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YPC_1726	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPC_1728	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPC_1732	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YPC_1734	COG2850	peptidyl-arginine hydroxylation
YPC_1736	COG0745	RESPONSE REGULATOR receiver
YPC_1738	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YPC_1742	COG1187	pseudouridine synthase activity
YPC_1743	COG0538	isocitrate dehydrogenase activity
YPC_1746	COG0840	transmembrane signaling receptor activity
YPC_1747	COG0702	epimerase
YPC_1748	COG1733	regulation of RNA biosynthetic process
YPC_1757	COG1522	sequence-specific DNA binding
YPC_1760	COG0604	alcohol dehydrogenase
YPC_1760	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_1760	COG3321	synthase
YPC_1762	COG1278	Cold shock
YPC_1766	COG1285	pathogenesis
YPC_1773	COG1360	Flagellar Motor Protein
YPC_1774	COG0643	Histidine kinase
YPC_1774	COG2198	Histidine kinase
YPC_1775	COG0835	chemotaxis
YPC_1776	COG2271	Major facilitator Superfamily
YPC_1777	COG0251	oxidation-reduction process
YPC_1779	COG2964	Protein conserved in bacteria
YPC_1783	COG0840	transmembrane signaling receptor activity
YPC_1784	COG0840	transmembrane signaling receptor activity
YPC_1785	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPC_1787	COG0745	RESPONSE REGULATOR receiver
YPC_1788	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPC_1791	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPC_1793	COG5295	Hep Hag repeat protein
YPC_1795	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPC_1802	COG1454	alcohol dehydrogenase
YPC_1802	COG1012	belongs to the aldehyde dehydrogenase family
YPC_1803	COG2095	MarC family integral membrane protein
YPC_1805	COG0601	transmembrane transport
YPC_1806	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPC_1807	COG0444	Belongs to the ABC transporter superfamily
YPC_1808	COG4608	Belongs to the ABC transporter superfamily
YPC_1818	COG2350	Protein conserved in bacteria
YPC_1819	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPC_1820	COG3328	transposase activity
YPC_1821	COG1607	acyl-coa hydrolase
YPC_1828	COG3047	cAMP biosynthetic process
YPC_1833	COG0134	indole-3-glycerol-phosphate synthase activity
YPC_1833	COG0135	phosphoribosylanthranilate isomerase activity
YPC_1835	COG0512	Glutamine amidotransferase of anthranilate synthase
YPC_1840	COG0009	L-threonylcarbamoyladenylate synthase
YPC_1841	COG1187	pseudouridine synthase activity
YPC_1843	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_1844	COG0616	signal peptide processing
YPC_1848	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPC_1849	COG0583	DNA-binding transcription factor activity
YPC_1851	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YPC_1852	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YPC_1853	COG0671	phosphoesterase, PA-phosphatase related
YPC_1854	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPC_1855	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPC_1858	COG0023	Translation Initiation Factor
YPC_1862	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPC_1863	COG2879	small protein
YPC_1864	COG1966	Carbon starvation protein
YPC_1866	COG2271	Major facilitator Superfamily
YPC_1867	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPC_1868	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPC_1871	COG4658	electron transport chain
YPC_1872	COG3708	Transcriptional regulator
YPC_1872	COG2207	Transcriptional regulator
YPC_1880	COG2274	protein secretion by the type I secretion system
YPC_1882	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPC_1883	COG2274	protein secretion by the type I secretion system
YPC_1886	COG1879	ABC-type sugar transport system periplasmic component
YPC_1888	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_1890	COG0673	inositol 2-dehydrogenase activity
YPC_1891	COG0385	Bile acid
YPC_1894	COG5339	Protein conserved in bacteria
YPC_1896	COG0114	fumarate hydratase activity
YPC_1898	COG2814	Major facilitator Superfamily
YPC_1899	COG0583	DNA-binding transcription factor activity
YPC_1900	COG1940	carbohydrate kinase activity
YPC_1902	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPC_1903	COG0038	chloride channel
YPC_1904	COG1609	Transcriptional regulator
YPC_1907	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPC_1908	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPC_1909	COG1116	anion transmembrane transporter activity
YPC_1910	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPC_1919	COG0440	acetolactate synthase activity
YPC_1920	COG1011	Hydrolase
YPC_1923	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPC_1924	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPC_1925	COG0589	response to stress
YPC_1928	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPC_1929	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPC_1932	COG0531	amino acid
YPC_1934	COG0745	RESPONSE REGULATOR receiver
YPC_1935	COG2205	protein histidine kinase activity
YPC_1936	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPC_1943	COG3038	cytochrome b561
YPC_1948	COG3591	Belongs to the peptidase S1B family
YPC_1951	COG1643	Atp-dependent helicase
YPC_1953	COG2390	Transcriptional regulator
YPC_1954	COG0246	Mannitol dehydrogenase
YPC_1955	COG3784	Protein of unknown function (DUF1318)
YPC_1957	COG2911	Protein conserved in bacteria
YPC_1958	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPC_1959	COG3187	Heat shock protein
YPC_1960	COG3042	response to heat
YPC_1961	COG1285	pathogenesis
YPC_1963	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPC_1963	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPC_1963	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPC_1963	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPC_1965	COG0657	acetylesterase activity
YPC_1965	COG2755	lipolytic protein G-D-S-L family
YPC_1969	COG4166	transmembrane transport
YPC_1970	COG2866	Carboxypeptidase
YPC_1971	COG4948	Mandelate Racemase Muconate Lactonizing
YPC_1972	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPC_1974	COG1943	Transposase
YPC_1979	COG3106	COG3106 Predicted ATPase
YPC_1981	COG1983	PspC domain protein
YPC_1983	COG1842	Phage shock protein A
YPC_1984	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPC_1987	COG4166	transmembrane transport
YPC_1988	COG4168	peptide transport system, permease
YPC_1989	COG4171	peptide transport system, permease
YPC_1992	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPC_1992	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPC_1994	COG3104	oligopeptide transport
YPC_1997	COG0625	glutathione transferase activity
YPC_2001	COG3895	Periplasmic Protein
YPC_2004	COG3133	Outer membrane lipoprotein
YPC_2006	COG2194	sulfuric ester hydrolase activity
YPC_2007	COG1309	transcriptional regulator
YPC_2009	COG1902	pentaerythritol trinitrate reductase activity
YPC_2011	COG0346	lactoylglutathione lyase activity
YPC_2012	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YPC_2014	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPC_2016	COG0791	NLP P60 protein
YPC_2017	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPC_2018	COG0583	DNA-binding transcription factor activity
YPC_2019	COG2814	Major facilitator Superfamily
YPC_2020	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPC_2021	COG0307	riboflavin synthase, alpha
YPC_2026	COG4238	major outer membrane lipoprotein
YPC_2032	COG1376	ErfK ybiS ycfS ynhG family protein
YPC_2032	COG1388	LysM domain
YPC_2035	COG0719	Fe-S assembly protein
YPC_2036	COG0396	ATPase activity
YPC_2037	COG0719	Fe-S assembly protein
YPC_2038	COG0316	Belongs to the HesB IscA family
YPC_2039	COG2050	protein possibly involved in aromatic compounds catabolism
YPC_2040	COG0247	lactate metabolic process
YPC_2040	COG0277	FAD linked oxidase domain protein
YPC_2041	COG0628	permease
YPC_2043	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPC_2043	COG0574	Belongs to the PEP-utilizing enzyme family
YPC_2049	COG0791	NLP P60 protein
YPC_2058	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
YPC_2059	COG0386	Belongs to the glutathione peroxidase family
YPC_2062	COG0776	regulation of translation
YPC_2063	COG0072	phenylalanine-tRNA ligase activity
YPC_2063	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
YPC_2064	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
YPC_2073	COG4249	Peptidase C14 caspase catalytic subunit p20
YPC_2080	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPC_2081	COG1121	(ABC) transporter
YPC_2087	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPC_2089	COG3328	transposase activity
YPC_2090	COG1917	Cupin 2, conserved barrel domain protein
YPC_2092	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_2096	COG3842	ATPase activity
YPC_2097	COG1653	transport
YPC_2098	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPC_2099	COG1988	membrane-bound metal-dependent
YPC_2102	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPC_2104	COG0823	Involved in the tonB-independent uptake of proteins
YPC_2105	COG2814	Major facilitator Superfamily
YPC_2106	COG3121	Chaperone
YPC_2109	COG3121	Chaperone
YPC_2110	COG3539	Fimbrial protein
YPC_2112	COG0793	Belongs to the peptidase S41A family
YPC_2115	COG1956	GAF domain-containing protein
YPC_2116	COG2995	paraquat-inducible protein a
YPC_2122	COG3121	Chaperone
YPC_2131	COG1435	thymidine kinase activity
YPC_2136	COG0745	RESPONSE REGULATOR receiver
YPC_2138	COG0788	formyltetrahydrofolate deformylase activity
YPC_2139	COG3328	transposase activity
YPC_2141	COG0583	DNA-binding transcription factor activity
YPC_2143	COG0708	Exodeoxyribonuclease III
YPC_2144	COG0494	nUDIX hydrolase
YPC_2147	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPC_2148	COG0709	Synthesizes selenophosphate from selenide and ATP
YPC_2150	COG0778	Nitroreductase
YPC_2153	COG0252	asparaginase activity
YPC_2154	COG1335	isochorismatase
YPC_2155	COG3139	Protein of unknown function (DUF1315)
YPC_2159	COG3713	MltA-interacting MipA family protein
YPC_2160	COG2766	serine protein kinase
YPC_2163	COG0583	DNA-binding transcription factor activity
YPC_2166	COG2814	Major facilitator Superfamily
YPC_2168	COG2719	SpoVR family
YPC_2174	COG1104	cysteine desulfurase activity
YPC_2176	COG3328	transposase activity
YPC_2208	COG3328	transposase activity
YPC_2227	COG0582	viral genome integration into host DNA
YPC_2229	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPC_2230	COG2951	lytic endotransglycosylase activity
YPC_2235	COG2894	cell division
YPC_2236	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YPC_2237	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPC_2238	COG0318	PFAM AMP-dependent synthetase and ligase
YPC_2240	COG3065	identical protein binding
YPC_2243	COG1199	ATP-dependent helicase activity
YPC_2244	COG0251	oxidation-reduction process
YPC_2247	COG0800	Aldolase
YPC_2248	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPC_2249	COG1737	Transcriptional regulator
YPC_2250	COG0469	pyruvate kinase activity
YPC_2252	COG1560	Kdo2-lipid A biosynthetic process
YPC_2253	COG0739	heme binding
YPC_2254	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPC_2256	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPC_2261	COG0494	nUDIX hydrolase
YPC_2263	COG1801	Protein of unknown function DUF72
YPC_2264	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPC_2269	COG3102	Protein conserved in bacteria
YPC_2275	COG0728	peptidoglycan biosynthetic process
YPC_2276	COG0673	inositol 2-dehydrogenase activity
YPC_2278	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPC_2285	COG3381	protein complex oligomerization
YPC_2288	COG1940	carbohydrate kinase activity
YPC_2289	COG0584	glycerophosphoryl diester phosphodiesterase
YPC_2291	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPC_2292	COG3833	ABC-type maltose transport systems, permease component
YPC_2296	COG0659	secondary active sulfate transmembrane transporter activity
YPC_2299	COG2912	Transglutaminase-like superfamily
YPC_2300	COG3094	Invasion gene expression up-regulator, SirB
YPC_2301	COG2890	protein-(glutamine-N5) methyltransferase activity
YPC_2306	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPC_2311	COG0012	GTP binding
YPC_2321	COG5002	protein histidine kinase activity
YPC_2330	COG0500	methyltransferase
YPC_2334	COG3328	transposase activity
YPC_2344	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPC_2349	COG0402	S-adenosylhomocysteine deaminase activity
YPC_2353	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YPC_2364	COG0673	inositol 2-dehydrogenase activity
YPC_2372	COG3328	transposase activity
YPC_2373	COG3328	transposase activity
YPC_2397	COG2197	response regulator
YPC_2400	COG3136	membrane protein required for alginate biosynthesis
YPC_2404	COG1113	amino acid transport
YPC_2407	COG2837	iron assimilation
YPC_2412	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPC_2412	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPC_2412	COG0506	proline dehydrogenase activity
YPC_2419	COG2515	1-aminocyclopropane-1-carboxylate deaminase
YPC_2422	COG1191	sigma factor activity
YPC_2429	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
YPC_2431	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPC_2432	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPC_2435	COG1677	Flagellar hook-basal body complex protein FliE
YPC_2437	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YPC_2439	COG1157	protein secretion by the type III secretion system
YPC_2440	COG2882	bacterial-type flagellum organization
YPC_2443	COG1580	Controls the rotational direction of flagella during chemotaxis
YPC_2448	COG1987	bacterial-type flagellum assembly
YPC_2452	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPC_2453	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_2454	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_2455	COG1129	ABC transporter
YPC_2458	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_2459	COG3347	Dehydrogenase
YPC_2459	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_2460	COG2390	Transcriptional regulator
YPC_2462	COG1256	bacterial-type flagellum assembly
YPC_2470	COG4786	Flagellar basal body rod
YPC_2472	COG1749	Flagellar hook protein flgE
YPC_2473	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPC_2474	COG1558	bacterial-type flagellum-dependent cell motility
YPC_2475	COG1815	bacterial-type flagellum-dependent cell motility
YPC_2477	COG2747	anti-sigma28 factor FlgM
YPC_2478	COG3418	PFAM FlgN family protein
YPC_2486	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPC_2487	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPC_2494	COG2372	response to copper ion
YPC_2495	COG1528	Iron-storage protein
YPC_2501	COG1770	oligopeptidase
YPC_2504	COG3141	response to X-ray
YPC_2505	COG0513	Belongs to the DEAD box helicase family
YPC_2510	COG1760	l-serine dehydratase
YPC_2511	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YPC_2512	COG2368	4-hydroxyphenylacetate
YPC_2516	COG3971	2-oxopent-4-enoate hydratase activity
YPC_2518	COG3384	dioxygenase
YPC_2519	COG1012	belongs to the aldehyde dehydrogenase family
YPC_2522	COG1846	Transcriptional regulator
YPC_2523	COG1253	flavin adenine dinucleotide binding
YPC_2524	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPC_2524	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPC_2525	COG3715	PTS system
YPC_2526	COG3716	PTS system mannose fructose sorbose family IID component
YPC_2531	COG3447	MASE1 domain protein
YPC_2531	COG5001	Diguanylate cyclase
YPC_2531	COG5002	protein histidine kinase activity
YPC_2533	COG2226	methyltransferase
YPC_2535	COG1278	Cold shock
YPC_2538	COG1113	amino acid transport
YPC_2544	COG2207	Transcriptional regulator
YPC_2546	COG1132	(ABC) transporter
YPC_2556	COG3328	transposase activity
YPC_2557	COG2223	nitrite transmembrane transporter activity
YPC_2562	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPC_2570	COG3122	Protein conserved in bacteria
YPC_2576	COG0534	Mate efflux family protein
YPC_2580	COG4948	Mandelate Racemase Muconate Lactonizing
YPC_2582	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_2583	COG3011	Protein conserved in bacteria
YPC_2584	COG2271	Major facilitator Superfamily
YPC_2586	COG1470	cell adhesion involved in biofilm formation
YPC_2586	COG1388	LysM domain
YPC_2587	COG3328	transposase activity
YPC_2591	COG2925	Exonuclease
YPC_2592	COG0531	amino acid
YPC_2594	COG0371	Dehydrogenase
YPC_2595	COG1129	ABC transporter
YPC_2596	COG1129	ABC transporter
YPC_2597	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_2599	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPC_2602	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YPC_2604	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPC_2604	COG0131	Imidazoleglycerol-phosphate dehydratase
YPC_2605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YPC_2608	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPC_2608	COG0140	phosphoribosyl-ATP diphosphatase activity
YPC_2610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPC_2611	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPC_2615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPC_2618	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPC_2619	COG1120	ATPase activity
YPC_2623	COG0076	glutamate decarboxylase activity
YPC_2624	COG4114	ferric iron reductase
YPC_2625	COG1253	flavin adenine dinucleotide binding
YPC_2626	COG2982	Protein involved in outer membrane biogenesis
YPC_2629	COG0489	protein tyrosine kinase activity
YPC_2631	COG1943	Transposase
YPC_2637	COG2814	Major facilitator Superfamily
YPC_2639	COG1346	cytolysis
YPC_2643	COG2949	membrane
YPC_2644	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPC_2648	COG2311	Membrane
YPC_2650	COG0477	Major facilitator Superfamily
YPC_2651	COG0583	DNA-binding transcription factor activity
YPC_2657	COG1136	(ABC) transporter
YPC_2659	COG0303	'Molybdopterin
YPC_2661	COG3328	transposase activity
YPC_2663	COG0488	(ABC) transporter
YPC_2693	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPC_2694	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YPC_2697	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_2700	COG3425	synthase
YPC_2701	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_2702	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPC_2703	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPC_2705	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_2712	COG2920	part of a sulfur-relay system
YPC_2717	COG1832	CoA-binding protein
YPC_2719	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
YPC_2721	COG0210	DNA helicase
YPC_2722	COG3304	Inner membrane component domain
YPC_2723	COG1289	transmembrane transporter activity
YPC_2724	COG3070	regulator of competence-specific genes
YPC_2726	COG2885	chlorophyll binding
YPC_2726	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPC_2728	COG1943	Transposase
YPC_2730	COG1067	ATP-dependent peptidase activity
YPC_2732	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPC_2735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPC_2736	COG1943	Transposase
YPC_2738	COG3130	regulation of translation
YPC_2740	COG3009	Protein conserved in bacteria
YPC_2741	COG3008	intermembrane lipid transfer
YPC_2741	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPC_2742	COG2995	paraquat-inducible protein a
YPC_2743	COG0488	(ABC) transporter
YPC_2745	COG0633	Ferredoxin
YPC_2745	COG3217	Mosc domain protein beta barrel domain protein
YPC_2749	COG0308	aminopeptidase N
YPC_2756	COG1448	Aminotransferase
YPC_2758	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPC_2759	COG3108	Peptidase M15
YPC_2760	COG2989	Protein conserved in bacteria
YPC_2764	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
YPC_2765	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
YPC_2766	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPC_2768	COG3173	Aminoglycoside phosphotransferase
YPC_2770	COG2835	tetraacyldisaccharide 4'-kinase activity
YPC_2772	COG1278	Cold shock
YPC_2773	COG5383	Protein conserved in bacteria
YPC_2776	COG2333	competence protein COMEC
YPC_2776	COG0658	competence protein
YPC_2779	COG0539	negative regulation of cytoplasmic translation
YPC_2785	COG0252	asparaginase activity
YPC_2786	COG1944	ATP diphosphatase activity
YPC_2788	COG2116	formate transmembrane transporter activity
YPC_2789	COG1882	Formate acetyltransferase
YPC_2791	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPC_2792	COG2814	Major facilitator Superfamily
YPC_2795	COG2814	Major facilitator Superfamily
YPC_2797	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPC_2799	COG3107	peptidoglycan biosynthetic process
YPC_2799	COG1674	ftsk spoiiie
YPC_2802	COG0492	ferredoxin-NADP+ reductase activity
YPC_2805	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPC_2809	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YPC_2816	COG1278	Cold shock
YPC_2818	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPC_2821	COG2990	Protein conserved in bacteria
YPC_2822	COG3593	DNA synthesis involved in DNA repair
YPC_2823	COG2431	L-lysine efflux transmembrane transporter activity
YPC_2825	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPC_2826	COG0028	Belongs to the TPP enzyme family
YPC_2828	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPC_2829	COG0702	epimerase
YPC_2830	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPC_2833	COG1605	Chorismate mutase
YPC_2834	COG1126	abc transporter atp-binding protein
YPC_2835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPC_2836	COG4215	(ABC) transporter
YPC_2837	COG4160	amino acid transport
YPC_2842	COG1120	ATPase activity
YPC_2849	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPC_2852	COG1177	transmembrane transport
YPC_2853	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPC_2854	COG3842	ATPase activity
YPC_2855	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPC_2858	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPC_2859	COG2985	domain, Protein
YPC_2859	COG0569	domain protein
YPC_2862	COG0671	phosphoesterase, PA-phosphatase related
YPC_2863	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPC_2864	COG1349	DNA-binding transcription factor activity
YPC_2867	COG0814	amino acid
YPC_2868	COG0814	amino acid
YPC_2870	COG1686	Belongs to the peptidase S11 family
YPC_2871	COG2011	ABC-type metal ion transport system permease component
YPC_2877	COG0625	glutathione transferase activity
YPC_2878	COG4771	TonB-dependent receptor
YPC_2880	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPC_2884	COG0583	DNA-binding transcription factor activity
YPC_2885	COG2855	membrane
YPC_2887	COG3188	usher protein
YPC_2888	COG3121	Chaperone
YPC_2891	COG3710	Transcriptional regulator
YPC_2892	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPC_2892	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPC_2892	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YPC_2893	COG1105	Belongs to the carbohydrate kinase PfkB family
YPC_2896	COG0494	nUDIX hydrolase
YPC_2897	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_2898	COG1129	ABC transporter
YPC_2899	COG1129	ABC transporter
YPC_2902	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YPC_2907	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_2911	COG1312	Catalyzes the dehydration of D-mannonate
YPC_2913	COG0246	Mannitol dehydrogenase
YPC_2914	COG2186	Transcriptional regulator
YPC_2917	COG0523	cobalamin synthesis protein
YPC_2918	COG0671	phosphoesterase, PA-phosphatase related
YPC_2920	COG0791	NLP P60 protein
YPC_2924	COG2200	EAL domain
YPC_2925	COG4166	transmembrane transport
YPC_2926	COG4174	ABC transporter (Permease)
YPC_2927	COG4239	(ABC) transporter, permease
YPC_2928	COG4172	Belongs to the ABC transporter superfamily
YPC_2929	COG4172	Belongs to the ABC transporter superfamily
YPC_2932	COG2814	Major facilitator Superfamily
YPC_2933	COG1187	pseudouridine synthase activity
YPC_2934	COG1061	Type III restriction enzyme res subunit
YPC_2936	COG1943	Transposase
YPC_2939	COG3082	Protein of unknown function (DUF1414)
YPC_2940	COG3083	sulfuric ester hydrolase activity
YPC_2942	COG3157	Type VI secretion system effector, Hcp
YPC_2947	COG2723	6-phospho-beta-galactosidase activity
YPC_2948	COG1737	Transcriptional regulator
YPC_2952	COG3299	homolog of phage Mu protein gp47
YPC_2962	COG4386	tail sheath protein
YPC_2966	COG3622	Belongs to the hyi family
YPC_2967	COG1349	DNA-binding transcription factor activity
YPC_2968	COG0235	Class ii aldolase
YPC_2969	COG3395	kinase activity
YPC_2979	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPC_2985	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YPC_2987	COG2223	nitrite transmembrane transporter activity
YPC_2988	COG0642	Histidine kinase
YPC_2988	COG2198	Histidine kinase
YPC_2989	COG0642	Histidine kinase
YPC_2989	COG2198	Histidine kinase
YPC_2991	COG0784	Response regulator, receiver
YPC_2991	COG2205	protein histidine kinase activity
YPC_2997	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPC_3002	COG0814	amino acid
YPC_3005	COG1199	ATP-dependent helicase activity
YPC_3007	COG0697	spore germination
YPC_3009	COG1982	Orn Lys Arg decarboxylase major
YPC_3010	COG0531	amino acid
YPC_3011	COG0531	amino acid
YPC_3012	COG1174	glycine betaine transport
YPC_3013	COG1125	glycine betaine transport
YPC_3014	COG1174	glycine betaine transport
YPC_3015	COG1732	Glycine betaine
YPC_3016	COG1732	Glycine betaine
YPC_3017	COG2897	thiosulfate sulfurtransferase activity
YPC_3020	COG0410	ABC transporter
YPC_3021	COG1122	ATPase activity
YPC_3025	COG4807	Protein conserved in bacteria
YPC_3029	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPC_3031	COG2261	transglycosylase associated protein
YPC_3034	COG1403	HNH endonuclease
YPC_3037	COG0277	FAD linked oxidase domain protein
YPC_3038	COG1686	Belongs to the peptidase S11 family
YPC_3041	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPC_3045	COG0513	Belongs to the DEAD box helicase family
YPC_3047	COG3328	transposase activity
YPC_3054	COG1943	Transposase
YPC_3058	COG0517	IMP dehydrogenase activity
YPC_3058	COG0516	GMP reductase activity
YPC_3060	COG1645	bacterial-type flagellum-dependent swarming motility
YPC_3065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPC_3066	COG2976	Protein conserved in bacteria
YPC_3077	COG3468	outer membrane autotransporter barrel domain protein
YPC_3080	COG3468	outer membrane autotransporter barrel domain protein
YPC_3086	COG2975	iron-sulfur cluster assembly
YPC_3087	COG0633	Ferredoxin
YPC_3088	COG0443	Heat shock 70 kDa protein
YPC_3091	COG0822	iron-sulfur transferase activity
YPC_3092	COG1104	cysteine desulfurase activity
YPC_3095	COG0483	inositol monophosphate 1-phosphatase activity
YPC_3097	COG1943	Transposase
YPC_3098	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPC_3099	COG3683	transport system, periplasmic component
YPC_3100	COG3711	transcriptional antiterminator
YPC_3101	COG2814	Major facilitator Superfamily
YPC_3106	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPC_3106	COG1017	nitric oxide dioxygenase activity
YPC_3107	COG2188	Transcriptional regulator
YPC_3108	COG0347	Belongs to the P(II) protein family
YPC_3109	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPC_3109	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPC_3110	COG2204	response regulator
YPC_3111	COG3170	Tfp pilus assembly protein FimV
YPC_3112	COG2205	protein histidine kinase activity
YPC_3121	COG0590	tRNA wobble adenosine to inosine editing
YPC_3122	COG0560	Phosphoserine phosphatase
YPC_3124	COG1737	Transcriptional regulator
YPC_3125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPC_3126	COG1943	Transposase
YPC_3129	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YPC_3133	COG0681	Belongs to the peptidase S26 family
YPC_3136	COG3086	response to oxidative stress
YPC_3140	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPC_3142	COG0513	Belongs to the DEAD box helicase family
YPC_3156	COG1984	allophanate hydrolase subunit 2
YPC_3157	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YPC_3158	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPC_3159	COG5212	phosphodiesterase
YPC_3161	COG3272	Protein of unknown function (DUF1722)
YPC_3167	COG2205	protein histidine kinase activity
YPC_3168	COG0745	RESPONSE REGULATOR receiver
YPC_3172	COG0033	Phosphoglucomutase
YPC_3173	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPC_3177	COG1917	Cupin 2, conserved barrel domain protein
YPC_3177	COG2169	Transcriptional regulator
YPC_3178	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPC_3179	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPC_3180	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPC_3182	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPC_3183	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPC_3184	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPC_3186	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPC_3187	COG4413	Urea transporter
YPC_3190	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPC_3199	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPC_3201	COG0747	negative chemotaxis
YPC_3203	COG1278	Cold shock
YPC_3211	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPC_3213	COG4175	Glycine betaine
YPC_3214	COG4176	ABC-type proline glycine betaine transport system permease component
YPC_3215	COG2113	Glycine betaine
YPC_3220	COG0582	viral genome integration into host DNA
YPC_3221	COG2963	transposase activity
YPC_3222	COG0582	viral genome integration into host DNA
YPC_3225	COG0596	Alpha beta hydrolase
YPC_3230	COG0735	belongs to the Fur family
YPC_3236	COG1943	Transposase
YPC_3238	COG2190	(PTS) system
YPC_3238	COG1263	PTS System
YPC_3238	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPC_3240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPC_3241	COG1940	carbohydrate kinase activity
YPC_3241	COG1846	Transcriptional regulator
YPC_3242	COG0647	UMP catabolic process
YPC_3244	COG0367	asparagine synthase
YPC_3252	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPC_3254	COG1702	phosphate starvation-inducible protein PhoH
YPC_3257	COG4535	Mg2 and Co2 transporter CorC
YPC_3258	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPC_3260	COG0765	amino acid transport
YPC_3261	COG0765	amino acid transport
YPC_3262	COG1126	abc transporter atp-binding protein
YPC_3263	COG2888	peptidyl-tyrosine sulfation
YPC_3267	COG1466	dna polymerase III delta subunit
YPC_3269	COG0799	negative regulation of ribosome biogenesis
YPC_3271	COG0768	penicillin binding
YPC_3272	COG0772	Belongs to the SEDS family
YPC_3273	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPC_3274	COG1686	Belongs to the peptidase S11 family
YPC_3278	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPC_3280	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPC_3283	COG1278	Cold shock
YPC_3284	COG2197	response regulator
YPC_3289	COG5265	(ABC) transporter
YPC_3290	COG3718	enzyme involved in inositol metabolism
YPC_3292	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPC_3293	COG0673	inositol 2-dehydrogenase activity
YPC_3294	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_3295	COG1129	ABC transporter
YPC_3296	COG1879	ABC-type sugar transport system periplasmic component
YPC_3299	COG3962	Belongs to the TPP enzyme family
YPC_3304	COG2373	Large extracellular alpha-helical protein
YPC_3305	COG1943	Transposase
YPC_3307	COG4953	penicillin-binding protein 1C
YPC_3309	COG3423	Transcriptional regulator
YPC_3320	COG2850	peptidyl-arginine hydroxylation
YPC_3321	COG3328	transposase activity
YPC_3328	COG0656	L-ascorbic acid biosynthetic process
YPC_3329	COG0667	Aldo Keto reductase
YPC_3335	COG0671	phosphoesterase, PA-phosphatase related
YPC_3335	COG2453	phosphatase
YPC_3336	COG2267	carboxylic ester hydrolase activity
YPC_3338	COG4589	Belongs to the CDS family
YPC_3339	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPC_3349	COG2501	S4 domain
YPC_3350	COG1943	Transposase
YPC_3353	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPC_3355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPC_3356	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPC_3357	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPC_3358	COG4181	ATPase activity
YPC_3359	COG2755	lipolytic protein G-D-S-L family
YPC_3360	COG0300	oxidoreductase activity
YPC_3361	COG3118	belongs to the thioredoxin family
YPC_3363	COG0330	HflC and HflK could
YPC_3364	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPC_3365	COG0789	Transcriptional regulator
YPC_3366	COG2217	Heavy metal translocating P-type atpase
YPC_3369	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPC_3375	COG2223	nitrite transmembrane transporter activity
YPC_3376	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPC_3376	COG4651	solute:proton antiporter activity
YPC_3377	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPC_3378	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPC_3382	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPC_3391	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPC_3395	COG0543	2 iron, 2 sulfur cluster binding
YPC_3395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPC_3396	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPC_3396	COG0543	2 iron, 2 sulfur cluster binding
YPC_3403	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPC_3407	COG2832	Protein of unknown function (DUF454)
YPC_3410	COG1196	nuclear chromosome segregation
YPC_3410	COG3264	Mechanosensitive ion channel
YPC_3411	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPC_3412	COG1309	transcriptional regulator
YPC_3413	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPC_3414	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPC_3416	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPC_3421	COG3695	enzyme binding
YPC_3422	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPC_3424	COG1946	Acyl-CoA thioesterase
YPC_3425	COG0004	ammonium transporteR
YPC_3426	COG0347	Belongs to the P(II) protein family
YPC_3427	COG1132	(ABC) transporter
YPC_3428	COG1132	(ABC) transporter
YPC_3429	COG1522	sequence-specific DNA binding
YPC_3432	COG4533	DNA binding
YPC_3434	COG0824	Thioesterase
YPC_3436	COG1555	photosystem II stabilization
YPC_3437	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPC_3438	COG0776	regulation of translation
YPC_3439	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPC_3444	COG0271	Belongs to the BolA IbaG family
YPC_3445	COG3056	Lipoprotein
YPC_3446	COG2223	nitrite transmembrane transporter activity
YPC_3449	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YPC_3450	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPC_3451	COG1845	cytochrome c oxidase, subunit III
YPC_3452	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPC_3454	COG2814	Major facilitator Superfamily
YPC_3456	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPC_3457	COG0693	protein deglycase activity
YPC_3461	COG0142	geranyltranstransferase activity
YPC_3465	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPC_3466	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPC_3469	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPC_3469	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPC_3475	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPC_3476	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPC_3477	COG1862	Preprotein translocase
YPC_3479	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
YPC_3480	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YPC_3481	COG0450	alkyl hydroperoxide reductase
YPC_3486	COG0366	Alpha amylase catalytic
YPC_3488	COG1114	Component of the transport system for branched-chain amino acids
YPC_3490	COG5002	protein histidine kinase activity
YPC_3491	COG0745	RESPONSE REGULATOR receiver
YPC_3493	COG0420	3'-5' exonuclease activity
YPC_3494	COG0419	ATPase involved in DNA repair
YPC_3495	COG1940	carbohydrate kinase activity
YPC_3503	COG2226	methyltransferase
YPC_3507	COG1943	Transposase
YPC_3520	COG1943	Transposase
YPC_3521	COG0583	DNA-binding transcription factor activity
YPC_3522	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPC_3527	COG1477	protein flavinylation
YPC_3531	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPC_3532	COG1805	sodium ion transport
YPC_3533	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPC_3535	COG3034	peptidoglycan biosynthetic process
YPC_3536	COG0121	glutamine amidotransferase
YPC_3538	COG1960	acyl-CoA dehydrogenase activity
YPC_3540	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPC_3549	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPC_3560	COG2814	Major facilitator Superfamily
YPC_3561	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPC_3563	COG1846	Transcriptional regulator
YPC_3564	COG1566	PFAM secretion protein HlyD family protein
YPC_3565	COG2814	Major facilitator Superfamily
YPC_3566	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPC_3567	COG3118	belongs to the thioredoxin family
YPC_3570	COG0045	succinate-CoA ligase (ADP-forming) activity
YPC_3570	COG1042	CoA-binding domain protein
YPC_3570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPC_3571	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPC_3572	COG5544	Lipoprotein
YPC_3579	COG0542	response to heat
YPC_3581	COG0564	pseudouridine synthase activity
YPC_3582	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPC_3583	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPC_3584	COG1943	Transposase
YPC_3586	COG1605	Chorismate mutase
YPC_3586	COG0077	Prephenate dehydratase
YPC_3589	COG0077	Prephenate dehydratase
YPC_3589	COG1605	Chorismate mutase
YPC_3590	COG1605	Chorismate mutase
YPC_3590	COG0287	Prephenate dehydrogenase
YPC_3591	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPC_3592	COG3279	Response regulator of the LytR AlgR family
YPC_3593	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPC_3594	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPC_3595	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPC_3596	COG3137	Salt-induced outer membrane protein
YPC_3597	COG1943	Transposase
YPC_3605	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPC_3606	COG4137	Cytochrome C assembly protein
YPC_3607	COG4536	flavin adenine dinucleotide binding
YPC_3612	COG2918	glutathione biosynthetic process
YPC_3613	COG1238	metal cluster binding
YPC_3614	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPC_3619	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YPC_3620	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
YPC_3628	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPC_3631	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_3632	COG1129	ABC transporter
YPC_3636	COG3783	Cytochrome b(562)
YPC_3637	COG3038	cytochrome b561
YPC_3639	COG3381	protein complex oligomerization
YPC_3640	COG3302	dmso reductase anchor subunit
YPC_3641	COG0437	4 iron, 4 sulfur cluster binding
YPC_3642	COG0243	molybdopterin cofactor binding
YPC_3643	COG0235	Class ii aldolase
YPC_3644	COG1349	DNA-binding transcription factor activity
YPC_3647	COG1943	Transposase
YPC_3648	COG1129	ABC transporter
YPC_3649	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_3650	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_3651	COG3623	hexulose-6-phosphate isomerase
YPC_3652	COG1070	Carbohydrate kinase
YPC_3653	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPC_3653	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPC_3655	COG0024	Methionine aminopeptidase
YPC_3658	COG4771	TonB-dependent receptor
YPC_3660	COG1858	cytochrome C peroxidase
YPC_3661	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPC_3665	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPC_3668	COG2376	Dihydroxyacetone kinase
YPC_3669	COG1028	Short-chain dehydrogenase reductase Sdr
YPC_3670	COG1063	alcohol dehydrogenase
YPC_3671	COG0698	ribose 5-phosphate isomerase
YPC_3673	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
YPC_3674	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPC_3675	COG1388	LysM domain
YPC_3675	COG4942	peptidase
YPC_3680	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
YPC_3683	COG0529	Catalyzes the synthesis of activated sulfate
YPC_3695	COG0720	synthase
YPC_3696	COG0602	queuosine metabolic process
YPC_3702	COG3956	TIGRFAM MazG family protein
YPC_3704	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPC_3705	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YPC_3707	COG4999	Histidine kinase
YPC_3707	COG2205	protein histidine kinase activity
YPC_3707	COG3437	response regulator, receiver
YPC_3707	COG3850	Histidine kinase
YPC_3708	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPC_3710	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPC_3712	COG2860	membrane
YPC_3719	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPC_3720	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPC_3721	COG1120	ATPase activity
YPC_3722	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YPC_3723	COG1643	Atp-dependent helicase
YPC_3724	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPC_3726	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YPC_3727	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
YPC_3728	COG0617	tRNA 3'-terminal CCA addition
YPC_3729	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPC_3735	COG0842	Transport permease protein
YPC_3736	COG1131	(ABC) transporter
YPC_3737	COG0288	reversible hydration of carbon dioxide
YPC_3738	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPC_3739	COG2132	Multicopper oxidase
YPC_3744	COG0697	spore germination
YPC_3748	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPC_3750	COG1943	Transposase
YPC_3752	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPC_3754	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPC_3755	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPC_3756	COG2186	Transcriptional regulator
YPC_3757	COG1113	amino acid transport
YPC_3758	COG3725	Membrane protein required for beta-lactamase induction
YPC_3759	COG3725	Membrane protein required for beta-lactamase induction
YPC_3760	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPC_3762	COG4969	Belongs to the N-Me-Phe pilin family
YPC_3763	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPC_3764	COG1459	type II secretion system
YPC_3766	COG0237	dephospho-CoA kinase activity
YPC_3774	COG0582	viral genome integration into host DNA
YPC_3779	COG2927	DNA polymerase III (CHI subunit)
YPC_3780	COG0525	valine-tRNA ligase activity
YPC_3782	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPC_3783	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
YPC_3784	COG2731	YhcH YjgK YiaL family protein
YPC_3787	COG0601	transmembrane transport
YPC_3788	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPC_3789	COG0444	Belongs to the ABC transporter superfamily
YPC_3795	COG2188	Transcriptional regulator
YPC_3796	COG3624	Phosphonate C-P lyase system protein PhnG
YPC_3797	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPC_3798	COG3626	phosphonate metabolism
YPC_3799	COG3627	carbon phosphorus lyase activity
YPC_3800	COG4107	phosphonate C-P lyase system protein PhnK
YPC_3801	COG4778	phosphonate C-P lyase system protein PhnL
YPC_3802	COG3454	Phosphonate metabolism
YPC_3803	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPC_3804	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPC_3805	COG0702	epimerase
YPC_3808	COG3842	ATPase activity
YPC_3809	COG0395	ABC-type sugar transport system, permease component
YPC_3811	COG1653	transport
YPC_3815	COG3153	acetyltransferase
YPC_3821	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPC_3824	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPC_3825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPC_3830	COG0513	Belongs to the DEAD box helicase family
YPC_3833	COG2801	Transposase and inactivated derivatives
YPC_3837	COG3710	Transcriptional regulator
YPC_3841	COG1256	bacterial-type flagellum assembly
YPC_3843	COG1706	bacterial-type flagellum-dependent cell motility
YPC_3844	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
YPC_3845	COG4786	Flagellar basal body rod
YPC_3846	COG4787	bacterial-type flagellum-dependent cell motility
YPC_3847	COG1749	Flagellar hook protein flgE
YPC_3848	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPC_3849	COG1558	bacterial-type flagellum-dependent cell motility
YPC_3850	COG1815	bacterial-type flagellum-dependent cell motility
YPC_3851	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPC_3860	COG2204	response regulator
YPC_3864	COG1987	bacterial-type flagellum assembly
YPC_3865	COG1684	flagellar biosynthetic protein fliR
YPC_3866	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPC_3873	COG4592	Periplasmic binding protein
YPC_3881	COG4964	Belongs to the GSP D family
YPC_3882	COG4964	Belongs to the GSP D family
YPC_3891	COG0848	biopolymer transport protein
YPC_3892	COG0811	peptide transport
YPC_3893	COG0626	cystathionine gamma-synthase activity
YPC_3894	COG0586	Pfam SNARE associated Golgi protein
YPC_3895	COG2207	Transcriptional regulator
YPC_3896	COG1979	alcohol dehydrogenase
YPC_3898	COG0656	L-ascorbic acid biosynthetic process
YPC_3901	COG2132	Multicopper oxidase
YPC_3902	COG0204	Acyl-transferase
YPC_3903	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPC_3904	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPC_3905	COG0583	DNA-binding transcription factor activity
YPC_3906	COG0187	DNA topoisomerase II activity
YPC_3907	COG3150	esterase
YPC_3908	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YPC_3910	COG3151	Protein conserved in bacteria
YPC_3911	COG0494	nUDIX hydrolase
YPC_3912	COG1538	Outer membrane efflux protein
YPC_3915	COG0754	glutathionylspermidine amidase activity
YPC_3916	COG3384	dioxygenase
YPC_3921	COG0531	amino acid
YPC_3925	COG3025	triphosphatase activity
YPC_3926	COG4991	sh3 domain protein
YPC_3929	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPC_3934	COG0358	DNA primase activity
YPC_3935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPC_3952	COG0251	oxidation-reduction process
YPC_3961	COG1289	transmembrane transporter activity
YPC_3965	COG0395	ABC-type sugar transport system, permease component
YPC_3967	COG1653	transport
YPC_3968	COG1609	Transcriptional regulator
YPC_3969	COG3459	Glycosyltransferase 36 associated
YPC_3970	COG3842	ATPase activity
YPC_3974	COG3210	domain, Protein
YPC_3975	COG3210	domain, Protein
YPC_3978	COG3210	domain, Protein
YPC_3979	COG3210	domain, Protein
YPC_3980	COG3210	domain, Protein
YPC_3981	COG3210	domain, Protein
YPC_3982	COG2831	hemolysin activation secretion protein
YPC_3983	COG4245	von Willebrand factor, type A
YPC_3986	COG4245	von Willebrand factor, type A
YPC_3989	COG3247	response to pH
YPC_3991	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPC_3991	COG1902	pentaerythritol trinitrate reductase activity
YPC_3994	COG1451	nucleotide metabolic process
YPC_3995	COG0673	inositol 2-dehydrogenase activity
YPC_3998	COG1943	Transposase
YPC_4005	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
YPC_4006	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPC_4008	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YPC_4009	COG0564	pseudouridine synthase activity
YPC_4019	COG3501	Rhs element vgr protein
YPC_4032	COG0417	DNA replication proofreading
YPC_4033	COG0586	Pfam SNARE associated Golgi protein
YPC_4035	COG1178	ABC-type Fe3 transport system permease component
YPC_4036	COG4143	(ABC) transporter
YPC_4040	COG2814	Major facilitator Superfamily
YPC_4044	COG0473	3-isopropylmalate dehydrogenase activity
YPC_4046	COG1943	Transposase
YPC_4050	COG1022	Amp-dependent synthetase and ligase
YPC_4051	COG0028	Belongs to the TPP enzyme family
YPC_4054	COG1943	Transposase
YPC_4055	COG1609	Transcriptional regulator
YPC_4060	COG3116	cell division
YPC_4061	COG0768	penicillin binding
YPC_4062	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YPC_4063	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPC_4066	COG0772	Belongs to the SEDS family
YPC_4070	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPC_4071	COG0849	cell division
YPC_4072	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPC_4078	COG0494	nUDIX hydrolase
YPC_4082	COG0435	Glutathione S-transferase
YPC_4083	COG2259	Doxx family
YPC_4085	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPC_4086	COG4575	ribosome binding
YPC_4090	COG0586	Pfam SNARE associated Golgi protein
YPC_4093	COG2271	Major facilitator Superfamily
YPC_4095	COG0246	Mannitol dehydrogenase
YPC_4096	COG2721	sulfolactate sulfo-lyase activity
YPC_4098	COG1943	Transposase
YPC_4100	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPC_4102	COG2966	Psort location CytoplasmicMembrane, score
YPC_4103	COG1280	lysine exporter protein (LysE YggA)
YPC_4104	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPC_4105	COG0505	Belongs to the CarA family
YPC_4107	COG1943	Transposase
YPC_4113	COG0196	riboflavin kinase activity
YPC_4115	COG0583	DNA-binding transcription factor activity
YPC_4119	COG1584	GPR1 FUN34 yaaH family protein
YPC_4122	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPC_4132	COG0745	RESPONSE REGULATOR receiver
YPC_4133	COG3045	CreA protein
YPC_4134	COG2207	Transcriptional regulator
YPC_4134	COG3708	Transcriptional regulator
YPC_4137	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPC_4138	COG0741	lytic transglycosylase activity
YPC_4141	COG2199	diguanylate cyclase activity
YPC_4142	COG2885	chlorophyll binding
YPC_4143	COG0488	(ABC) transporter
YPC_4144	COG0488	(ABC) transporter
YPC_4148	COG0560	Phosphoserine phosphatase
YPC_4150	COG3726	membrane protein affecting hemolysin expression
YPC_4155	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPC_4157	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPC_4161	COG4667	esterase of the alpha-beta hydrolase superfamily
YPC_4162	COG4667	esterase of the alpha-beta hydrolase superfamily
YPC_4164	COG2823	Periplasmic or secreted lipoprotein
YPC_4166	COG0456	acetyltransferase
YPC_4167	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YPC_4173	COG3706	GGDEF domain
YPC_4179	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPC_4180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPC_4184	COG0859	PFAM glycosyl transferase family 9
YPC_4187	COG2390	Transcriptional regulator
YPC_4188	COG2390	Transcriptional regulator
YPC_4199	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPC_4199	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPC_4199	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPC_4200	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPC_4201	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPC_4202	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPC_4203	COG2207	Transcriptional regulator
YPC_4205	COG4269	membrane
YPC_4215	COG2963	transposase activity
YPC_4216	COG2801	Transposase and inactivated derivatives
YPC_4219	COG1401	restriction endodeoxyribonuclease activity
YPC_4223	COG1295	ribonuclease BN
YPC_4224	COG1011	Hydrolase
YPC_4226	COG0174	glutamine synthetase
YPC_4227	COG3852	Histidine kinase
YPC_4229	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPC_4234	COG1943	Transposase
YPC_4238	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPC_4238	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPC_4239	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPC_4240	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPC_4241	COG3084	Protein conserved in bacteria
YPC_4243	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPC_4244	COG3328	transposase activity
YPC_4253	COG0435	Glutathione S-transferase
YPC_4254	COG0583	DNA-binding transcription factor activity
YPC_4255	COG1741	Belongs to the pirin family
YPC_4258	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPC_4262	COG2823	Periplasmic or secreted lipoprotein
YPC_4264	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YPC_4267	COG0784	Response regulator, receiver
YPC_4267	COG2198	Histidine kinase
YPC_4267	COG5002	protein histidine kinase activity
YPC_4269	COG1242	4 iron, 4 sulfur cluster binding
YPC_4270	COG0067	glutamate synthase
YPC_4270	COG0069	glutamate synthase activity
YPC_4270	COG0070	glutamate synthase
YPC_4271	COG0493	'glutamate synthase
YPC_4273	COG2969	positive regulation of protein catabolic process
YPC_4274	COG0625	glutathione transferase activity
YPC_4277	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YPC_4278	COG3105	Protein conserved in bacteria
YPC_4279	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPC_4280	COG1943	Transposase
YPC_4282	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPC_4284	COG5007	Belongs to the BolA IbaG family
YPC_4285	COG3113	response to antibiotic
YPC_4286	COG2854	intermembrane phospholipid transfer
YPC_4287	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPC_4288	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPC_4289	COG1127	ABC transporter
YPC_4290	COG0530	calcium, potassium:sodium antiporter activity
YPC_4291	COG0517	IMP dehydrogenase activity
YPC_4291	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPC_4292	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPC_4293	COG3117	lipopolysaccharide transmembrane transporter activity
YPC_4294	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPC_4295	COG1137	ATPase activity
YPC_4296	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPC_4298	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPC_4299	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPC_4301	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPC_4306	COG1609	Transcriptional regulator
YPC_4307	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPC_4307	COG1263	PTS System
YPC_4308	COG0366	Alpha amylase catalytic
YPC_4309	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPC_4311	COG3783	Cytochrome b(562)
YPC_4313	COG0312	modulator of DNA gyrase
YPC_4315	COG2732	(Barnase) inhibitor
YPC_4323	COG0583	DNA-binding transcription factor activity
YPC_4335	COG0312	modulator of DNA gyrase
YPC_4336	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPC_4337	COG3164	Protein of unknown function
YPC_4338	COG1530	ribonuclease E activity
YPC_4340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPC_4341	COG1792	Involved in formation and maintenance of cell shape
YPC_4342	COG1077	Cell shape determining protein MreB Mrl
YPC_4343	COG2199	diguanylate cyclase activity
YPC_4343	COG2200	EAL domain
YPC_4344	COG0604	alcohol dehydrogenase
YPC_4345	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
YPC_4348	COG0511	ligase activity, forming carbon-carbon bonds
YPC_4349	COG0439	Biotin carboxylase
YPC_4352	COG3924	membrane
YPC_4353	COG4145	pantothenate transmembrane transporter activity
YPC_4356	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPC_4357	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YPC_4362	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPC_4364	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPC_4365	COG3133	Outer membrane lipoprotein
YPC_4367	COG1278	Cold shock
YPC_4368	COG1278	Cold shock
YPC_4373	COG0625	glutathione transferase activity
YPC_4375	COG1069	ribulokinase activity
YPC_4377	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_4378	COG1129	ABC transporter
YPC_4380	COG1560	Kdo2-lipid A biosynthetic process
YPC_4382	COG0025	NhaP-type Na H and K H
YPC_4383	COG2252	PERMEase
YPC_4384	COG3077	Addiction module antitoxin, RelB DinJ family
YPC_4388	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPC_4390	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPC_4391	COG0431	NADPH-dependent FMN reductase
YPC_4395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPC_4396	COG1869	D-ribose catabolic process
YPC_4398	COG1917	Cupin 2, conserved barrel domain protein
YPC_4398	COG2207	Transcriptional regulator
YPC_4399	COG0673	inositol 2-dehydrogenase activity
YPC_4402	COG3209	COG3209 Rhs family protein
YPC_4404	COG3501	Rhs element vgr protein
YPC_4411	COG3209	COG3209 Rhs family protein
YPC_4415	COG3501	Rhs element vgr protein
YPC_4431	COG2801	Transposase and inactivated derivatives
YPC_4435	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPC_4436	COG0058	SHG alpha-glucan phosphorylase activity
YPC_4442	COG3275	phosphorelay sensor kinase activity
YPC_4443	COG1388	LysM domain
YPC_4443	COG2373	Large extracellular alpha-helical protein
YPC_4443	COG4932	domain protein
YPC_4444	COG2373	Large extracellular alpha-helical protein
YPC_4444	COG1388	LysM domain
YPC_4444	COG4932	domain protein
YPC_4450	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPC_4451	COG2095	MarC family integral membrane protein
YPC_4455	COG3265	gluconokinase activity
YPC_4457	COG2610	gluconate transmembrane transporter activity
YPC_4459	COG1609	Transcriptional regulator
YPC_4460	COG1741	Belongs to the pirin family
YPC_4463	COG0745	RESPONSE REGULATOR receiver
YPC_4465	COG0191	fructose-bisphosphate aldolase activity
YPC_4467	COG1879	ABC-type sugar transport system periplasmic component
YPC_4468	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPC_4471	COG2081	HI0933 family
YPC_4472	COG0306	phosphate transporter
YPC_4476	COG0589	response to stress
YPC_4480	COG0339	signal peptide processing
YPC_4482	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPC_4483	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPC_4484	COG3835	regulator
YPC_4487	COG2610	gluconate transmembrane transporter activity
YPC_4488	COG1929	Belongs to the glycerate kinase type-1 family
YPC_4493	COG1295	ribonuclease BN
YPC_4494	COG2134	cdp-diacylglycerol pyrophosphatase
YPC_4497	COG2200	EAL domain
YPC_4498	COG1942	4-Oxalocrotonate Tautomerase
YPC_4499	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPC_4500	COG0612	Peptidase, M16
YPC_4504	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPC_4505	COG2199	diguanylate cyclase activity
YPC_4505	COG2200	EAL domain
YPC_4507	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YPC_4508	COG4608	Belongs to the ABC transporter superfamily
YPC_4509	COG0444	Belongs to the ABC transporter superfamily
YPC_4510	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPC_4511	COG0601	transmembrane transport
YPC_4512	COG0601	transmembrane transport
YPC_4513	COG0747	negative chemotaxis
YPC_4515	COG2831	hemolysin activation secretion protein
YPC_4517	COG1943	Transposase
YPC_4519	COG2271	Major facilitator Superfamily
YPC_4522	COG2197	response regulator
YPC_4523	COG2194	sulfuric ester hydrolase activity
YPC_4526	COG2986	histidine ammonia-lyase
YPC_4529	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YPC_4532	COG4607	ABC-type enterochelin transport system periplasmic component
YPC_4535	COG4604	ABC transporter, ATP-binding protein
YPC_4545	COG0582	viral genome integration into host DNA
YPC_4547	COG2207	Transcriptional regulator
YPC_4547	COG1609	Transcriptional regulator
YPC_4548	COG4214	carbohydrate transport
YPC_4550	COG4213	ABC transporter substrate-binding protein
YPC_4552	COG1070	Carbohydrate kinase
YPC_4554	COG3121	Chaperone
YPC_4555	COG3188	usher protein
YPC_4557	COG3188	usher protein
YPC_4560	COG3274	enterobacterial common antigen metabolic process
YPC_4563	COG2801	Transposase and inactivated derivatives
YPC_4573	COG2864	formate dehydrogenase
YPC_4574	COG0437	4 iron, 4 sulfur cluster binding
YPC_4579	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPC_4586	COG3722	fumarate hydratase activity
YPC_4588	COG2213	PTS system mannitol-specific
YPC_4588	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPC_4594	COG2818	Glycosylase
YPC_4597	COG2885	chlorophyll binding
YPC_4600	COG0366	Alpha amylase catalytic
YPC_4602	COG3977	Valine--pyruvate aminotransferase
YPC_4607	COG5645	(Lipo)protein
YPC_4608	COG0823	Involved in the tonB-independent uptake of proteins
YPC_4609	COG0823	Involved in the tonB-independent uptake of proteins
YPC_4610	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPC_4611	COG2423	ornithine cyclodeaminase activity
YPC_4613	COG2801	Transposase and inactivated derivatives
YPC_4614	COG0561	phosphatase activity
YPC_4615	COG0187	DNA topoisomerase II activity
YPC_4616	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YPC_4617	COG0592	DNA-directed DNA polymerase activity
YPC_4620	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YPC_4623	COG0706	membrane insertase activity
YPC_4629	COG2252	PERMEase
YPC_4631	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPC_4632	COG0765	amino acid transport
YPC_4633	COG0765	amino acid transport
YPC_4634	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPC_4636	COG0704	Plays a role in the regulation of phosphate uptake
YPC_4638	COG0581	inorganic phosphate transmembrane transporter activity
YPC_4639	COG0573	inorganic phosphate transmembrane transporter activity
YPC_4640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPC_4642	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YPC_4654	COG3312	ion transport
YPC_4663	COG5599	Phosphatase
YPC_4673	COG2801	Transposase and inactivated derivatives
YPC_4688	COG4886	Leucine-rich repeat (LRR) protein
YPC_4715	COG2207	Transcriptional regulator
YPC_4726	COG4669	(LipO)protein
YPC_4729	COG5599	Phosphatase
YPC_4730	COG2963	transposase activity
YPC_4735	COG4372	Transposase
YPC_4736	COG2801	Transposase and inactivated derivatives
YPC_4754	COG2801	Transposase and inactivated derivatives
YPC_4760	COG2801	Transposase and inactivated derivatives
YPC_4766	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
YPC_4767	COG5301	cellulose 1,4-beta-cellobiosidase activity
YPC_4767	COG5301	cellulose 1,4-beta-cellobiosidase activity
YPC_4774	COG3941	tape measure
YPC_4794	COG1475	DNA binding
YPC_4795	COG1475	DNA binding
YPC_4796	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPC_4812	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPC_4824	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
YPC_4826	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPC_4849	COG1475	DNA binding
YPC_4867	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPC_4870	COG3344	reverse transcriptase
YPC_4875	COG3328	transposase activity
YPC_4889	COG4683	PFAM Phage derived protein Gp49-like (DUF891)