locus-tag class description CH60_10 ENOG4105CBX hi0933 family CH60_100 ENOG4107V9H nitrite transporter CH60_1003 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CH60_1005 ENOG4105C9A Phoh family CH60_1007 ENOG4108JU5 Magnesium and cobalt efflux protein CH60_1008 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) CH60_1009 ENOG4107RP9 extracellular solute-binding protein, family 3 CH60_101 ENOG4105WZK nitrite reductase NADPH small subunit CH60_1010 ENOG4105EAD ABC transporter CH60_1011 ENOG4105DRP amino acid AbC transporter CH60_1012 ENOG4105CDA abc transporter atp-binding protein CH60_1013 ENOG4107PAI alpha helical protein CH60_1016 ENOG4105DJF DNA polymerase III, delta' subunit CH60_1018 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) CH60_102 ENOG4107QZF nitrite reductase NADPH large subunit CH60_1020 ENOG4105CJN penicillin-binding protein CH60_1021 ENOG4105CNI cell division protein FtsW CH60_1022 ENOG4105K6T rare lipoprotein A CH60_1023 ENOG4105DZ1 carboxypeptidase CH60_1027 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) CH60_1028 ENOG4107Z6W Protein CrcB homolog CH60_1029 ENOG4105VEQ Cold shock protein CH60_103 ENOG4105DZC cytosine deaminase CH60_1031 ENOG4108N8T regulatoR CH60_1036 ENOG4108JJ7 ABC transporter CH60_1038 ENOG4105DH8 myo-inositol catabolism CH60_1040 ENOG4105EDK PfkB domain protein CH60_1041 ENOG4105CK5 oxidoreductase CH60_1042 ENOG4105CNN ABC, transporter CH60_1043 ENOG4105C2J ABC transporter CH60_1044 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH60_1045 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) CH60_1047 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) CH60_1048 ENOG4105C26 Dehydrogenase CH60_1053 ENOG4105DN3 alpha-2-macroglobulin domain protein CH60_1054 ENOG4108JQB penicillin-binding protein 1C CH60_1055 ENOG4105HVQ Regulatory factor of maltose metabolism CH60_106 ENOG41060NJ transcriptional regulator CH60_1060 ENOG4108WC9 type VI secretion system effector, hcp1 family CH60_1065 ENOG4105EZE Cupin 4 family protein CH60_107 ENOG4105F8D glycoside hydrolase family 4 CH60_1070 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CH60_1073 ENOG4107SET aldo keto reductase CH60_1074 ENOG4105EQ2 LysR family Transcriptional regulator CH60_1077 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH60_1078 ENOG4108RS6 transposase CH60_1079 ENOG4108Q2G (LipO)protein CH60_108 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CH60_1080 ENOG4105DY2 Paraquat-inducible protein b CH60_1081 ENOG4105F1S paraquat-inducible protein a CH60_1082 ENOG4105C5H ABC transporter CH60_1084 ENOG4105QVC MOSC domain-containing protein CH60_1085 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) CH60_1087 ENOG4105CD8 aminopeptidase N CH60_109 ENOG4105D7A ATP-binding protein CH60_1091 ENOG4105CGF Aromatic amino acid aminotransferase CH60_1092 ENOG4105C5X domain protein CH60_1093 ENOG4105EAQ (twin-arginine translocation) pathway signal CH60_1094 ENOG4105DIT ErfK YbiS YcfS YnhG family protein CH60_1095 ENOG4108RS6 transposase CH60_1097 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) CH60_1098 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) CH60_1099 ENOG4106371 Methyltransferase CH60_11 ENOG4105CJ3 phosphate transporter CH60_1100 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups CH60_1102 ENOG4105W49 UPF0434 protein CH60_1103 ENOG4105VEQ Cold shock protein CH60_1104 ENOG4105E32 cytoplasmic protein CH60_1107 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 CH60_111 ENOG4105C8Y Acetylornithine aminotransferase CH60_1110 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) CH60_1115 ENOG4105EUR Domain-Containing protein CH60_1115 ENOG4105EUR Domain-Containing protein CH60_1116 ENOG4105HDK L-asparaginase CH60_1117 ENOG4105DDY UPF0142 protein ycaO CH60_1118 ENOG4105TMB Formate nitrite transporter CH60_1119 ENOG4105C6N Formate acetyltransferase CH60_112 ENOG410613R integral membrane protein, YccS YhfK family CH60_1121 ENOG4105F1A Pyruvate formate-lyase CH60_1122 ENOG4108ISG Major Facilitator CH60_1124 ENOG4105D1H recombination factor protein RarA CH60_1127 ENOG4105CNU cell division protein FtsK CH60_1128 ENOG4105EW9 transcriptional regulator AsnC family CH60_1129 ENOG4105C3M thioredoxin reductase CH60_1130 ENOG4108JJ9 ABC, transporter CH60_1131 ENOG4108JJ8 (ABC) transporter CH60_1133 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) CH60_1134 ENOG4108RS6 transposase CH60_1135 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH60_1137 ENOG4105VEQ Cold shock protein CH60_1139 ENOG4105DJY efflux transporter, rnd family, mfp subunit CH60_114 ENOG4108UKZ OsmC family CH60_1140 ENOG4108MJ5 VirK protein CH60_1141 ENOG4105CPB ATP-dependent endonuclease of the OLD family CH60_1142 ENOG4105DWU Membrane CH60_1144 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CH60_1145 ENOG4105C7K acetolactate synthase CH60_1146 ENOG4105C5W Aldolase CH60_1147 ENOG4105CGD Nad-dependent epimerase dehydratase CH60_1148 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CH60_1149 ENOG41064MM (LipO)protein CH60_1150 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) CH60_1151 ENOG4105E5Z arginine transporter ATP-binding subunit CH60_1152 ENOG4106PMH Extracellular solute-binding protein family 3 CH60_1153 ENOG4105GBT ABC transporter CH60_1154 ENOG4105DMR ABC, transporter CH60_1155 ENOG4108I0N Transporter, RarD family, DMT superfamily protein CH60_1156 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) CH60_1157 ENOG410642S Nicotianamine synthase protein CH60_1158 ENOG4105E0A ABC, transporter CH60_1159 ENOG4105DQ5 transport system permease protein CH60_116 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) CH60_1164 ENOG4106TNF Periplasmic binding protein CH60_1166 ENOG4105RBQ inner membrane protein ybjO CH60_1167 ENOG4105D38 putrescine abc transporter CH60_1168 ENOG4105F38 ABC transporter, permease CH60_1169 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH60_1170 ENOG4107RUE extracellular solute-binding protein family 1 CH60_1171 ENOG4108RMJ sensory transduction regulator CH60_1172 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress CH60_1173 ENOG41090BQ Glutaredoxin CH60_1174 ENOG4105D0C transport protein CH60_1176 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CH60_1177 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CH60_1178 ENOG4107FB0 transcriptional regulator DeoR family CH60_1179 ENOG4105C44 Serine transporter CH60_118 ENOG4105DNZ Alpha Beta Hydrolase CH60_1180 ENOG4105DZ1 carboxypeptidase CH60_1181 ENOG4108UMI ABC transporter, permease CH60_1183 ENOG4105D01 (LipO)protein CH60_1186 ENOG4108TGY Glutathione S-transferase CH60_1187 ENOG4105D05 Receptor CH60_1189 ENOG4105EHG Permease protein CH60_1191 ENOG4108IQI permease CH60_1193 ENOG4105DUM transcriptional regulator, lysR family CH60_1194 ENOG4105HMI Membrane CH60_1195 ENOG4105EFU Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity) CH60_12 ENOG4108RS6 transposase CH60_120 ENOG4106FTQ Taurine ABC transporter, periplasmic CH60_1203 ENOG4107B2H carbonic anhydrase CH60_1207 ENOG4107QHF type ii secretion system protein e CH60_1208 ENOG4105D7Q type ii secretion system CH60_122 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CH60_1221 ENOG4105C8Q Methyl-accepting chemotaxis CH60_1223 ENOG4105EJC lysr family transcriptional regulator CH60_1224 ENOG4105RQF LysR family Transcriptional regulator CH60_1225 ENOG4105F27 Major Facilitator CH60_1226 ENOG41060NJ transcriptional regulator CH60_1227 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) CH60_123 ENOG4105E2B Taurine dioxygenase CH60_1233 ENOG4105CPC Aldo Keto reductase CH60_1236 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase CH60_1244 ENOG4105DSY exodeoxyribonuclease V, gamma CH60_1245 ENOG4107QXK peptidase CH60_1246 ENOG4107QKA exodeoxyribonuclease V beta CH60_1247 ENOG4107QYX exodeoxyribonuclease v alpha CH60_1249 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CH60_1252 ENOG4105CA3 membrane-bound lytic murein transglycosylase CH60_1253 ENOG4105CUZ uba thif-type nad fad binding protein CH60_1254 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) CH60_1255 ENOG4105C9B Cysteine desulfurase CH60_1257 ENOG4105ETT transcriptional Regulator, LysR family CH60_1258 ENOG4105M08 Membrane CH60_126 ENOG4105K64 Glycosyl transferase, family 2 CH60_1260 ENOG4105CIQ May have a role in processing of nucleic acids. It is probably not an exonuclease CH60_1261 ENOG4105EWT decarboxylase family CH60_1264 ENOG4108RS6 transposase CH60_1265 ENOG4105WP7 tRNA pseudouridine synthase C CH60_1266 ENOG4105DR9 pseudouridine synthase CH60_1267 ENOG4105QDK Flavodoxin CH60_127 ENOG4105C5H ABC transporter CH60_1271 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CH60_1277 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) CH60_1278 ENOG4105KNE Phosphatidate cytidylyltransferase CH60_1279 ENOG4105DZP Membrane-associated zinc metalloprotease CH60_1281 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) CH60_1285 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) CH60_1287 ENOG4105C0B DNA polymerase III (alpha subunit) CH60_1289 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase CH60_1290 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) CH60_1292 ENOG4105M1T rho-binding antiterminator CH60_1294 ENOG4108VWS Yaeq family CH60_1295 ENOG4108YZN class I peptide chain release factor CH60_1296 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion CH60_1298 ENOG4108R96 Methyltransferase, YaeB family CH60_1299 ENOG4108R8X outer membrane lipoprotein CH60_130 ENOG4105VKU nucleicacid-binding protein CH60_1300 ENOG4105D01 (LipO)protein CH60_1301 ENOG4108UMI ABC transporter, permease CH60_1303 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase CH60_131 ENOG4108YZY peptidylprolyl cis-trans isomerase CH60_1310 ENOG4105CV8 reductase CH60_1313 ENOG4105E9H Lytic Murein transglycosylase CH60_1315 ENOG4105D1A Methyltransferase CH60_1317 ENOG4108JDX DNA polymerase iii, epsilon subunit CH60_1319 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease CH60_1326 ENOG4105GIJ Glycine betaine CH60_1327 ENOG4108HQS Glycine betaine CH60_1328 ENOG4108IJ7 Glycine betaine CH60_1329 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH60_133 ENOG4108V1T peptidylprolyl cis-trans isomerase CH60_1334 ENOG4108WMJ Protein of unknown function (DUF2002) CH60_1336 ENOG4105CW0 outer membrane usher protein CH60_134 ENOG4105WWK YheO domain protein CH60_1348 ENOG4105CS6 Rhs element vgr protein CH60_1358 ENOG4105DWF phosphomethylpyrimidine kinase CH60_1360 ENOG4108ZGU inhibitor of vertebrate lysozyme CH60_1362 ENOG4105CFP Peptidase U32 CH60_1363 ENOG4105KWI UPF0339 protein CH60_1364 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH60_1365 ENOG4105EB3 Histidine kinase CH60_1370 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH60_1372 ENOG4108JPW Aminotransferase CH60_1374 ENOG4105F38 ABC transporter, permease CH60_1375 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component CH60_1376 ENOG4105R8A Heat shock protein CH60_1377 ENOG4105CJW magnesium transporter CH60_1378 ENOG4105C9X ppx gppa phosphatase CH60_1379 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) CH60_1380 ENOG4105C8U phosphate abc transporter CH60_1381 ENOG4105E2Z phosphate ABC transporter (Permease CH60_1383 ENOG4108C80 FliB family CH60_1384 ENOG4108C80 FliB family CH60_1385 ENOG4108MK9 spermidine N(1)-acetyltransferase CH60_1386 ENOG4108V3E phosphoribosylglycinamide formyltransferase CH60_1389 ENOG4108RS6 transposase CH60_139 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) CH60_1391 ENOG4105K89 arsenate reductase CH60_1392 ENOG4105ERG peptidase m48, ste24p CH60_1393 ENOG4105C02 permease CH60_1396 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CH60_1397 ENOG4105RH4 Glycine cleavage system transcriptional repressor CH60_1399 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CH60_14 ENOG4108M6U Universal stress protein A CH60_1400 ENOG4108RS6 transposase CH60_1402 ENOG4105CGZ zinc metallopeptidase CH60_1408 ENOG4105KUZ arsenate reductase CH60_1410 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC CH60_1411 ENOG4107Z33 ABC transporter, permease CH60_1412 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH60_1413 ENOG4105ENH Sulfatase CH60_1414 ENOG4105C4X radical SAM domain protein CH60_1415 ENOG4105S2T inner membrane protein YbcI CH60_1417 ENOG4105BZS acriflavin resistance protein CH60_1419 ENOG4105WH1 Two component transcriptional regulator luxr family CH60_142 ENOG4108RS6 transposase CH60_1420 ENOG4108ZNS ferredoxin-type protein NapF CH60_1421 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase CH60_1423 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) CH60_1424 ENOG4105CUW cytochrome C-TYPE protein CH60_1426 ENOG4105C6K Malic enzyme CH60_1433 ENOG4105H4F exported protein CH60_1434 ENOG4105E7K (LipO)protein CH60_1435 ENOG4105EZR dyp-type peroxidase family protein CH60_1440 ENOG4108R66 Conserved Protein CH60_1441 ENOG4105QEK Transcriptional regulator CH60_1443 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein CH60_1444 ENOG4108I5D sulfate abc transporter CH60_1445 ENOG4105ECW sulfate abc transporter CH60_1446 ENOG4108IJ6 ABC transporter CH60_1447 ENOG4105C6T cysteine synthase CH60_1449 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CH60_1450 ENOG41062D9 Histidine kinase CH60_1452 ENOG4105C87 Aminotransferase class I and II CH60_1454 ENOG4107RAQ aminopeptidase CH60_1456 ENOG4105E1V na solute symporter CH60_1459 ENOG4105DJY efflux transporter, rnd family, mfp subunit CH60_1460 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH60_1461 ENOG4105E0F Histidine kinase CH60_1463 ENOG4108RS6 transposase CH60_1464 ENOG4105C5Y PTS System CH60_1466 ENOG4105KZ7 phosphocarrier protein hpr CH60_1467 ENOG4105C6T cysteine synthase CH60_1468 ENOG4105EXN Sulfate transport protein CysZ CH60_1471 ENOG4105VRT cytoplasmic protein CH60_1480 ENOG4105D9N nucleoside CH60_1483 ENOG4105CPC Aldo Keto reductase CH60_1484 ENOG4105C5Q Transcriptional regulator CH60_1487 ENOG41072TH Protein of unknown function (DUF1479) CH60_1488 ENOG4105CHM Aminotransferase CH60_1489 ENOG4108VKM cytochrome b561 CH60_1491 ENOG4106B0W Curli production assembly transport component CsgG CH60_1493 ENOG4107Y60 (LipO)protein CH60_1495 ENOG4108NEM leader-binding protein dmsD CH60_1496 ENOG4107KGK dmso reductase anchor subunit CH60_1497 ENOG4105QAX Iron-sulfur CH60_1498 ENOG4107QY8 reductase CH60_1500 ENOG4108WC9 type VI secretion system effector, hcp1 family CH60_1505 ENOG4105CVE Lytic murein transglycosylase CH60_151 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) CH60_1515 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH60_1517 ENOG4105GQR Chaperone CH60_1518 ENOG4105CW0 outer membrane usher protein CH60_1520 ENOG4108SAJ Protein of unknown function (DUF1198) CH60_1522 ENOG4105VEQ Cold shock protein CH60_1523 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein CH60_1524 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CH60_1525 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH60_1526 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) CH60_1527 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) CH60_153 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) CH60_1534 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) CH60_1538 ENOG4105XXV Acid-resistance protein CH60_1539 ENOG4107SVH Potassium channel protein CH60_154 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) CH60_1540 ENOG41086WQ Protein CrcB homolog CH60_1541 ENOG41085Q9 Protein CrcB homolog CH60_1542 ENOG4105VZJ PTS System CH60_1543 ENOG4105CK1 PTS System CH60_1544 ENOG4105VCP PTS System CH60_1545 ENOG4105EZV Transcriptional regulator CH60_1550 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 CH60_1554 ENOG4105EEX Two component transcriptional regulator (Winged helix family CH60_1555 ENOG4105C08 Histidine kinase CH60_1559 ENOG4105XIQ Protein of unknown function (DUF2517) CH60_156 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal CH60_1560 ENOG4107SEY Conserved Protein CH60_1561 ENOG4105CVP deoxyribo-dipyrimidine photolyase CH60_1562 ENOG4107RF4 Phosphodiesterase CH60_1563 ENOG4107QNR UPF0135 protein CH60_1565 ENOG4105P4J Allophanate hydrolase, subunit 1 CH60_1566 ENOG4107R7A Allophanate hydrolase subunit 2 CH60_1580 ENOG4108IYU L-aspartate oxidase CH60_1582 ENOG41069PW sigma-e factor negative regulatory protein CH60_1583 ENOG4105VQK sigma E regulatory protein, MucB RseB CH60_1584 ENOG4105WMJ Positive regulator of sigma E, RseC MucC CH60_1587 ENOG4105C3F Signal peptidase i CH60_1591 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) CH60_1593 ENOG4108RS6 transposase CH60_1594 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding CH60_1595 ENOG4106G6Q Transcriptional regulator CH60_1600 ENOG4106G6Q Transcriptional regulator CH60_1602 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB CH60_1603 ENOG4108Z6B deaminase CH60_1609 ENOG4108RS6 transposase CH60_1610 ENOG4107WP9 Histidine kinase CH60_1611 ENOG4108SKK alpha helix protein CH60_1612 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CH60_1613 ENOG4105C4K Nad synthetase CH60_1614 ENOG4108YZA Nitrogen regulatory protein pii CH60_1617 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CH60_1620 ENOG4108MN2 Stationary phase inducible protein CsiE CH60_1621 ENOG4105D8G Major Facilitator superfamily CH60_1622 ENOG41065CD Exported protein CH60_1623 ENOG4105D7X high-affinity nickel-transporter CH60_1627 ENOG4105C3J Cysteine desulfurase CH60_1628 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins CH60_1631 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB CH60_1632 ENOG4108ZIT Ferredoxin, 2FE-2S CH60_1633 ENOG4105WVQ Fe-S assembly protein IscX CH60_1635 ENOG4105YYA enhanced serine sensitivity protein SseB CH60_1637 ENOG4108MGN ATP-binding component of a transport system CH60_1638 ENOG4108MGN ATP-binding component of a transport system CH60_1647 ENOG4105N21 Membrane CH60_1648 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CH60_165 ENOG4105VPB 50S ribosomal protein L30 CH60_1651 ENOG4105VPD cellular component movement CH60_1653 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) CH60_1655 ENOG4108RS6 transposase CH60_1656 ENOG4108WC9 type VI secretion system effector, hcp1 family CH60_1663 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 CH60_1664 ENOG4107PN8 YfeABCD locus regulator CH60_1665 ENOG4105FGM Fructosamine kinase CH60_1666 ENOG4105CC5 ABC transporter CH60_1667 ENOG4105CC5 ABC transporter CH60_1668 ENOG4105DIK (ABC) transporter CH60_1669 ENOG4105DSE periplasmic solute binding protein CH60_167 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CH60_1673 ENOG41087WU CH60_1678 ENOG4105CSS phenylalanyl-tRNA synthetase (alpha subunit) CH60_1679 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) CH60_168 ENOG41067V7 50S ribosomal protein L36 CH60_1680 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) CH60_1683 ENOG4108V06 Glutathione peroxidase CH60_1684 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) CH60_1692 ENOG4108QBX (LipO)protein CH60_1696 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CH60_1698 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) CH60_1699 ENOG4105IPI Membrane CH60_1700 ENOG4105CQB FAD linked oxidase domain protein CH60_1701 ENOG4105KA0 thioesterase Superfamily protein CH60_1702 ENOG4108Z4V iron-sulfur cluster assembly CH60_1703 ENOG4105DIW FeS assembly protein SUFB CH60_1704 ENOG4105C3K feS assembly ATPase SufC CH60_1705 ENOG4105JRK feS assembly protein SufD CH60_1708 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CH60_171 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) CH60_1712 ENOG4108RS6 transposase CH60_1713 ENOG4105KMX major outer membrane lipoprotein CH60_1714 ENOG4105CA9 Pyruvate kinase CH60_1718 ENOG4108R6K riboflavin synthase, subunit alpha CH60_1719 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase CH60_1720 ENOG4105CZQ inner membrane transport protein YdhC CH60_1721 ENOG4105F52 Transcriptional regulator CH60_1724 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CH60_1725 ENOG4105K4H Nlp p60 protein CH60_1727 ENOG4105M2J Glutaredoxin CH60_1728 ENOG4105DH5 Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity) CH60_1729 ENOG4108UYE Lactoylglutathione lyase CH60_1731 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CH60_1732 ENOG4108WUH Transcriptional regulator, TetR family CH60_1733 ENOG4105DIJ Phosphoethanolamine transferase CH60_1734 ENOG4105XZD Fe-S protein CH60_1735 ENOG4107RGM aldo keto reductase CH60_1737 ENOG4108XTF Outer Membrane Lipoprotein CH60_1739 ENOG410642K Lysozyme inhibitor CH60_174 ENOG4105W1Y Transcriptional regulator CH60_1743 ENOG4108K3A Glutathione S-transferase CH60_1744 ENOG4108ZR5 Conserved Protein CH60_1745 ENOG41069YE inner membrane protein yohC CH60_1746 ENOG4105DUX Transporter CH60_1748 ENOG4105Q4T oxidoreductase CH60_1749 ENOG4108JQ2 peptide transport system atp-binding protein CH60_175 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system CH60_1750 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein CH60_1751 ENOG4108EU3 peptide transport system, permease CH60_1752 ENOG4108I5W peptide transport system, permease protein CH60_1753 ENOG4108HIY periplasmic CH60_1754 ENOG4108RS6 transposase CH60_1759 ENOG4105CM6 amino acid regulated cytosolic protein CH60_1761 ENOG4105FM1 phage shock protein C CH60_1762 ENOG4105YYT phage shock protein B CH60_1763 ENOG41087YS Phage shock protein A CH60_1764 ENOG4105E51 psp operon transcriptional activator CH60_1765 ENOG4108RS6 transposase CH60_1766 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CH60_1767 ENOG4107S8C mandelate racemase muconate lactonizing CH60_1768 ENOG4105KXI murein peptide amidase A CH60_1769 ENOG4107QSI ABC, transporter CH60_177 ENOG4105C1A potassium transporter peripheral membrane CH60_1775 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) CH60_1777 ENOG4105KT7 mgtC SapB transporter CH60_1779 ENOG41090X5 Heat shock protein hslJ CH60_1780 ENOG4105C5I Dehydrogenase CH60_1781 ENOG4107H52 Dicarboxylate transport CH60_1782 ENOG410689M (LipO)protein CH60_1783 ENOG4105WXT Conserved Protein CH60_1784 ENOG4105DEI Mannitol dehydrogenase CH60_1785 ENOG4105DKT Transcriptional regulator CH60_1787 ENOG4105CQ7 ATP-dependent helicase CH60_1790 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap CH60_1792 ENOG4105DS1 cytochrome b561 CH60_1796 ENOG4108RS6 transposase CH60_1797 ENOG4105CTD carboxy-peptidase CH60_1798 ENOG4105JJR Histidine kinase CH60_1799 ENOG4107EXC regulatoR CH60_18 ENOG4105DGW oligopeptidase A CH60_1801 ENOG4105D5Q Arginine ornithine antiporter CH60_1802 ENOG4105C5D exported protein CH60_1803 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CH60_1804 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CH60_1805 ENOG4105Q9Y Universal stress protein CH60_1806 ENOG4105DS0 Transcriptional regulator, Crp Fnr family CH60_1807 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CH60_181 ENOG4105C79 DNA protecting protein DprA CH60_1811 ENOG4105PAD Hydrolase CH60_1812 ENOG4105M71 acetolactate synthase 1 regulatory subunit CH60_1813 ENOG4105C7K acetolactate synthase CH60_1818 ENOG4105FYV Amp nucleosidase CH60_1820 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CH60_1821 ENOG4107UWC ABC, transporter CH60_1822 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH60_1824 ENOG41060NJ transcriptional regulator CH60_1825 ENOG4105CMQ Chloride channel CH60_1826 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CH60_1828 ENOG4105DAG ROK family CH60_1829 ENOG4106NZI LysR family Transcriptional regulator CH60_183 ENOG4108WI1 Dna topoisomerase CH60_1830 ENOG4105D94 Major Facilitator Superfamily CH60_1831 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) CH60_1832 ENOG4105C9Q fumarate hydratase class II CH60_1833 ENOG4105EIP mannose-6-phosphate isomerase CH60_1834 ENOG4106J39 exported protein CH60_1836 ENOG4105DHU Bile acid CH60_1837 ENOG4105D9R oxidoreductase CH60_1839 ENOG4105CNN ABC, transporter CH60_1841 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator CH60_1845 ENOG4108JJA ABC, transporter CH60_1846 ENOG4105C42 Type I secretion membrane fusion protein (HlyD CH60_1848 ENOG4108JJA ABC, transporter CH60_1849 ENOG4105M9B inner membrane protein ydgK CH60_1853 ENOG4105UEI Transcriptional Regulator AraC Family CH60_1854 ENOG4105D6A Electron transport complex CH60_1855 ENOG4108UQQ Electron transport complex CH60_1857 ENOG4105CSM endonuclease III CH60_1858 ENOG4105EXW epimerase dehydratase CH60_1859 ENOG4105CSP Major Facilitator Superfamily CH60_186 ENOG4108Z0R Transferase CH60_1861 ENOG4105D22 carbon starvation protein CH60_1862 ENOG4105VCD cytoplasmic protein CH60_1863 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CH60_1865 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CH60_1866 ENOG41061RM osmotically inducible lipoprotein CH60_1867 ENOG4108ZJT translation initiation factor, Sui1 CH60_1870 ENOG4105CFV Tetratricopeptide repeat protein CH60_1871 ENOG4105Q4A inner membrane protein yciS CH60_1872 ENOG4105EYK Phosphatidylglycerophosphatase B CH60_1873 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) CH60_1874 ENOG4107QM5 aconitate hydratase CH60_1876 ENOG4107R11 Transcriptional regulator CH60_1877 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CH60_1879 ENOG4105RKX Protein of unknown function (DUF2498) CH60_1880 ENOG4105ERU peptidase CH60_1881 ENOG4105UBK short-chain dehydrogenase reductase CH60_1882 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase CH60_1883 ENOG4105FE9 pseudouridine synthase CH60_1884 ENOG4107RTD sua5 ycio yrdc ywlc family protein CH60_1885 ENOG4105DB7 PHP domain protein CH60_1887 ENOG4105DDQ anthranilate synthase CH60_1889 ENOG4105DK0 Indole-3-glycerol phosphate synthase CH60_1893 ENOG4105EIF outer membrane protein W CH60_1898 ENOG4105NAU thioesterase Superfamily protein CH60_19 ENOG4105D6S protein involved in catabolism of external DNA CH60_1901 ENOG410822N TonB family CH60_1903 ENOG4105K9H YciI-like protein CH60_1906 ENOG4108T1M outer membrane protein x CH60_1910 ENOG4108JQ7 (ABC) transporter CH60_1911 ENOG4105C3U ABC transporter CH60_1912 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH60_1914 ENOG4107QSI ABC, transporter CH60_1915 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein CH60_1916 ENOG4108EKI Dehydrogenase CH60_1917 ENOG4107104 thymidine kinase CH60_1919 ENOG4105C6Y Udp-glucose 6-dehydrogenase CH60_1920 ENOG4105I93 response regulator CH60_1922 ENOG4105CIY formyltetrahydrofolate deformylase CH60_1925 ENOG4105SKE transcriptional Regulator LysR family CH60_1926 ENOG4105CGK Exodeoxyribonuclease III CH60_1927 ENOG4105M6F mutator MutT protein CH60_1928 ENOG4105MTM Protein of unknown function (DUF1496) CH60_1929 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CH60_1930 ENOG4105D4F Synthesizes selenophosphate from selenide and ATP (By similarity) CH60_1931 ENOG41069NU Nitroreductase CH60_1932 ENOG4105D07 Signal peptide peptidase, SppA CH60_1933 ENOG4105HDK L-asparaginase CH60_1934 ENOG4108RWI nicotinamidase CH60_1935 ENOG4105VUT cytoplasmic protein CH60_1938 ENOG4105DSB aldose 1-epimerase CH60_1939 ENOG4105GNX MltA-interacting MipA family protein CH60_194 ENOG4105CMM transposase CH60_1940 ENOG4105CYN Serine protein kinase CH60_1943 ENOG4105HEI LysR family (Transcriptional regulator CH60_1944 ENOG4105EUB pirin domain protein CH60_1945 ENOG4105CNH Multidrug resistance protein MdtL CH60_1947 ENOG4105ED1 spovr family CH60_1953 ENOG4105C3J Cysteine desulfurase CH60_1960 ENOG4105HRS Antitermination protein CH60_1962 ENOG4105NY2 NinB protein CH60_1968 ENOG4107R08 Integrase CH60_1970 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase CH60_1971 ENOG4105CVE Lytic murein transglycosylase CH60_1974 ENOG4107QMS site-determining protein CH60_1975 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) CH60_1976 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) CH60_1977 ENOG4105CEY Amp-dependent synthetase and ligase CH60_1978 ENOG4105Y4Z Outer Membrane Lipoprotein CH60_1979 ENOG41072GX Peptidase M22 Glycoprotease CH60_1980 ENOG4105DVT helicase CH60_1981 ENOG4105M4H endoribonuclease L-psp CH60_1984 ENOG4108UHU Aldolase CH60_1986 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CH60_1987 ENOG4106KNT transcriptional regulator CH60_1988 ENOG4105CA9 Pyruvate kinase CH60_1989 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase CH60_1990 ENOG4105DR5 peptidase CH60_1991 ENOG4105NXV High-affinity zinc uptake system protein CH60_1993 ENOG4105FAV ABC, transporter CH60_1998 ENOG4108TIT dATP pyrophosphohydrolase CH60_2 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CH60_20 ENOG4105DC8 reductase CH60_2001 ENOG4105D5G Transposase CH60_2002 ENOG41081XQ Conserved Protein CH60_2003 ENOG4105WJG Glutathione CH60_2007 ENOG4106ZCM YecM protein CH60_201 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) CH60_2012 ENOG4105CJR Integral membrane protein (MviN CH60_2013 ENOG4105EP9 oxidoreductase CH60_2014 ENOG4105D9U N-acetyltransferase CH60_2016 ENOG4105F3T (LipO)protein CH60_2017 ENOG4107XHZ cytoplasmic chaperone TorD family protein CH60_202 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) CH60_2020 ENOG4105E2R ROK family CH60_2021 ENOG4108QXE glycerophosphoryl diester phosphodiesterase CH60_2022 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CH60_2023 ENOG4108RS6 transposase CH60_2025 ENOG4105F38 ABC transporter, permease CH60_2026 ENOG4105EG2 ABC transporter, permease CH60_2030 ENOG4105CHH sulfate transporter CH60_2032 ENOG41063JG Transcriptional regulator CH60_2033 ENOG4108YY7 Invasion gene expression up-regulator SirB CH60_2034 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) CH60_2039 ENOG4105C5T Phosphoribosyl pyrophosphate synthase CH60_204 ENOG4108MXZ Esterase CH60_2040 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria CH60_2042 ENOG4105C3G gtp-binding protein CH60_205 ENOG4105WSB biofilm stress and motility protein A CH60_2051 ENOG4105ENX hydrolase CH60_2053 ENOG4105GR3 Histidine kinase CH60_206 ENOG4105CSU acyl-Coa dehydrogenase CH60_2062 ENOG4108WF3 methyltransferase CH60_207 ENOG4105C2N RNA methyltransferase TrmH family group 3 CH60_2075 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CH60_2076 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CH60_2077 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CH60_2079 ENOG41090B9 response to stress CH60_208 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) CH60_2080 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) CH60_2081 ENOG4105CZE histidine utilization repressor CH60_2090 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CH60_2093 ENOG4105EUR Domain-Containing protein CH60_2094 ENOG4105EUR Domain-Containing protein CH60_2095 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CH60_2096 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) CH60_2097 ENOG4108VYJ response regulator receiver protein CH60_2099 ENOG4105BZU Histidine kinase CH60_21 ENOG4107VHA regulatoR CH60_2100 ENOG4105C8Q Methyl-accepting chemotaxis CH60_2101 ENOG4105C8Q Methyl-accepting chemotaxis CH60_2105 ENOG4105WWK YheO domain protein CH60_2107 ENOG4105KME endoribonuclease L-psp CH60_2108 ENOG4105R9B Major Facilitator CH60_2109 ENOG4108V3W Chemotaxis protein, CheW CH60_2110 ENOG4105CBS Chea signal transduction histidine kinase CH60_2111 ENOG4105ER2 Ompa motb domain protein CH60_2112 ENOG4107RD7 Flagellar Motor Protein, MotA CH60_2113 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region CH60_2114 ENOG4105GEH Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways (By similarity) CH60_2115 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic CH60_2116 ENOG4105KT7 mgtC SapB transporter CH60_2117 ENOG4105C8Q Methyl-accepting chemotaxis CH60_2118 ENOG4105C8Q Methyl-accepting chemotaxis CH60_212 ENOG4105EPW hflc protein CH60_2120 ENOG4105VEQ Cold shock protein CH60_2123 ENOG4105GSJ Inner membrane protein ylaC CH60_2124 ENOG4108XM1 transcriptional regulator AsnC family CH60_2126 ENOG41061EV selenium-binding protein YdfZ CH60_2127 ENOG4105D6F Phosphatase CH60_2129 ENOG4105KVH Transcriptional regulator CH60_213 ENOG4107QJR hflk protein CH60_2130 ENOG4105ECR NmrA family CH60_2131 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor CH60_2133 ENOG4106NDP Transcriptional regulator CH60_2134 ENOG4108HMX isocitrate dehydrogenase (NADP) CH60_2135 ENOG4108R99 pseudouridine synthase CH60_2139 ENOG4107QTF adenylosuccinate lyase CH60_214 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CH60_2141 ENOG4105XJC Two component transcriptional regulator (Winged helix family CH60_2143 ENOG4105EZE Cupin 4 family protein CH60_2145 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) CH60_2147 ENOG4105D60 lipoprotein releasing system transmembrane protein CH60_2149 ENOG4105D60 lipoprotein releasing system transmembrane protein CH60_2150 ENOG4108JA2 transcriptioN-repair coupling factor CH60_2151 ENOG4107MBR 17 kDa surface antigen CH60_2156 ENOG4105CEP NADH dehydrogenase CH60_2158 ENOG4107QPA Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity) CH60_2161 ENOG41090DQ Lipoprotein CH60_2162 ENOG4105K59 histidine triad (HIT) protein CH60_2163 ENOG4105F9E Shikimate 5-dehydrogenase CH60_2164 ENOG4108RS6 transposase CH60_2165 ENOG4105CI1 PTS System CH60_2166 ENOG4105F8V Hydrolase, tatD family CH60_2167 ENOG4107QRG dna polymerase iii CH60_2169 ENOG4105HHA aminodeoxychorismate lyase CH60_2170 ENOG4105YAZ 4-amino-4-deoxychorismate lyase CH60_2171 ENOG4108RS6 transposase CH60_2172 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH60_2174 ENOG4105CHR reductase CH60_2175 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CH60_2178 ENOG4105VGS 50s ribosomal protein l32 CH60_2179 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein CH60_218 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CH60_2181 ENOG4105EI2 Pseudouridine synthase CH60_2182 ENOG4107QQB Ribonuclease E CH60_2183 ENOG41067V3 Antibiotic biosynthesis monooxygenase CH60_2187 ENOG4105PVA Biofilm formation regulatory protein BssS CH60_219 ENOG4105K8N protein family UPF0079, ATPase CH60_2190 ENOG4105DSF transport protein CH60_2194 ENOG4105VJY transcriptional regulator CH60_2195 ENOG4107YC3 synthase CH60_2196 ENOG4105ETT transcriptional Regulator, LysR family CH60_2198 ENOG4105C54 Major Facilitator superfamily CH60_22 ENOG4107QQ0 gntp family CH60_220 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) CH60_2200 ENOG4105CPC Aldo Keto reductase CH60_2201 ENOG4108Y1S CRISPR-associated protein, Csy4 family CH60_2202 ENOG4105M6W Crispr-associated protein, Csy3 family CH60_2203 ENOG4105DZX CRISPR-associated protein, Csy2 family CH60_2204 ENOG4105ENG CRISPR-associated protein, Csy1 family CH60_2205 ENOG4107IIZ CRISPR-associated helicase, Cas3 CH60_2206 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) CH60_2207 ENOG4105CUY Mechanosensitive ion channel CH60_221 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) CH60_2211 ENOG4105HY2 Glycosidase related protein CH60_2212 ENOG4105DRS transport system, permease CH60_2215 ENOG4105ETE Transcriptional regulator (LacI family CH60_2217 ENOG4108RS6 transposase CH60_2218 ENOG4108IJ9 (ABC) transporter CH60_2220 ENOG4105CKT filamentous hemagglutinin CH60_2224 ENOG4105CKT filamentous hemagglutinin CH60_2225 ENOG4105D5K Hemolysin activator protein CH60_2226 ENOG4105E3J oxidoreductase CH60_2227 ENOG4105DVW rieske (2Fe-2S) CH60_2228 ENOG4105C94 Transporter CH60_2229 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CH60_2230 ENOG4105EJC lysr family transcriptional regulator CH60_2231 ENOG4105FKQ transcriptional regulator CH60_2232 ENOG4105CNN ABC, transporter CH60_2233 ENOG4105C2J ABC transporter CH60_2234 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH60_2235 ENOG4105CPQ Dehydrogenase CH60_2239 ENOG4108T1M outer membrane protein x CH60_2245 ENOG4107R0W ABC transporter CH60_2246 ENOG4105E5Q amino acid AbC transporter CH60_2247 ENOG4105CDA abc transporter atp-binding protein CH60_2248 ENOG4107SDU Methyl-accepting chemotaxis CH60_225 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) CH60_2250 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction CH60_2251 ENOG4108MTB glycosyl transferase family CH60_2252 ENOG4105CEY Amp-dependent synthetase and ligase CH60_2254 ENOG4108IPT Naphthoate synthase CH60_2257 ENOG4105E4F Isochorismate synthase CH60_2259 ENOG4105TNS Conserved Protein CH60_2261 ENOG4105C01 Dihydroxy-acid dehydratase CH60_2265 ENOG4105C5I Dehydrogenase CH60_2266 ENOG4105K2J Transcriptional regulator CH60_2267 ENOG4105F32 YngK protein CH60_2268 ENOG4105CHR reductase CH60_2269 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CH60_2270 ENOG4108R66 Conserved Protein CH60_2273 ENOG4105C8S subunit m CH60_2274 ENOG4105D65 subunit l CH60_2276 ENOG4107UFS subunit j CH60_2279 ENOG4108IEH NADH dehydrogenase subunit g CH60_228 ENOG4105EGS Mechanosensitive ion channel CH60_2280 ENOG4107QIZ NADH dehydrogenase CH60_2281 ENOG4105GKE subunit e CH60_2283 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CH60_2285 ENOG4107NQ8 LysR family Transcriptional regulator CH60_2286 ENOG4105CHM Aminotransferase CH60_2288 ENOG4107QWE )-transporter CH60_2289 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 CH60_2293 ENOG4105C6K Malic enzyme CH60_2294 ENOG4107P2S Transcriptional regulator CH60_23 ENOG4105BZW Glycerate kinase CH60_2302 ENOG4105PTV Nudix Hydrolase CH60_2303 ENOG4108RE9 Phosphodiesterase CH60_2305 ENOG4105ECP epimerase CH60_2306 ENOG4108JEH abc transporter atp-binding protein CH60_2307 ENOG4106YG3 ABC transporter CH60_2308 ENOG4105DSP amino acid AbC transporter CH60_2309 ENOG4105E89 ABC transporter CH60_2310 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CH60_2311 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase CH60_2312 ENOG4105E96 Colicin v production protein CH60_2313 ENOG4108S3P Sporulation domain protein CH60_2314 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase CH60_2316 ENOG4105DQR SNARE associated Golgi CH60_2318 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CH60_2321 ENOG410631K Membrane CH60_2322 ENOG4106WZ1 flagella biosynthesis regulator CH60_2325 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH60_2327 ENOG4105MH2 YfcL protein CH60_2328 ENOG4108BPE -transporting atpase CH60_2329 ENOG4105EJ9 Membrane CH60_233 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) CH60_2332 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) CH60_2334 ENOG4108BY2 phosphohistidine phosphatase CH60_2337 ENOG4105KZW UPF0381 protein CH60_2338 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation CH60_2339 ENOG410903C (LipO)protein CH60_234 ENOG4105KPY Small multidrug resistance protein CH60_2340 ENOG4105KWW Biogenesis protein CH60_2341 ENOG4105KWW Biogenesis protein CH60_2342 ENOG4107QX9 Thiol disulfide interChange protein CH60_2343 ENOG4105DA4 cytochrome c-type biogenesis protein CH60_2345 ENOG4105X3C heme exporter protein CH60_2346 ENOG41060IM Heme exporter protein CH60_2347 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) CH60_2351 ENOG4108V0P LemA family CH60_2353 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA CH60_2355 ENOG4105M5J Cupin 2, conserved barrel domain protein CH60_2357 ENOG4105CHR reductase CH60_2358 ENOG41061NF Pectate lyase CH60_2359 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component CH60_236 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein CH60_2363 ENOG4105WEM extracellular solute-binding protein CH60_2364 ENOG4108PU9 oligogalacturonate-specific porin CH60_2365 ENOG4107K5X Membrane-bound metal-dependent hydrolase CH60_2366 ENOG4108ETY sodium dicarboxylate symporter CH60_2367 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CH60_2369 ENOG4105CAZ oligogalacturonide lyase CH60_237 ENOG4108ZVF (LipO)protein CH60_2370 ENOG4105C0R drug resistance transporter emrb qaca subfamily CH60_2371 ENOG4108VEV chaperone CH60_2374 ENOG4108VEV chaperone CH60_2375 ENOG4105H8W Fimbrial protein CH60_2378 ENOG4105CN1 protease CH60_2380 ENOG4108ZGC gaf domain protein CH60_2381 ENOG4105H2K paraquat-inducible protein a CH60_2382 ENOG4105DY2 Paraquat-inducible protein b CH60_2386 ENOG4105GQR Chaperone CH60_2389 ENOG4105WT8 Protein of unknown function (DUF1480) CH60_2395 ENOG4105CZE histidine utilization repressor CH60_2406 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CH60_2407 ENOG4105BZU Histidine kinase CH60_2408 ENOG4105EWV Sodium calcium exchanger membrane region CH60_2409 ENOG4105D5M phosphate starvation-inducible protein CH60_2412 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD CH60_2413 ENOG4105CND Glycosyl transferase, family 2 CH60_2414 ENOG4107BJW polysaccharide deacetylase CH60_2415 ENOG4108TUY outer membrane protein PgaA CH60_2416 ENOG4105H1N peptidase, M24 CH60_242 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CH60_2420 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CH60_2422 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CH60_2425 ENOG4107SJW iron permease, FTR1 CH60_2427 ENOG4105CSV Glutaminase CH60_2428 ENOG4105MVE transcriptional regulator CH60_2429 ENOG4105C85 amino acid CH60_2430 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CH60_2431 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH60_2434 ENOG4107RGD Major Facilitator superfamily CH60_2439 ENOG4105DJG MaoC domain protein dehydratase CH60_2440 ENOG4105CYC Transferase CH60_2442 ENOG4108Q9V regulatoR CH60_2447 ENOG4105CW0 outer membrane usher protein CH60_2449 ENOG4108MQF Chaperone CH60_245 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CH60_2453 ENOG4105EYM Major Facilitator superfamily CH60_2454 ENOG4105BZ1 (ABC) transporter CH60_2457 ENOG4105C0W non-ribosomal peptide synthetase CH60_246 ENOG4108RC0 Electron transport protein CH60_2461 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase CH60_2462 ENOG4107ZSV Receptor CH60_247 ENOG4105BZ8 glutamate synthase CH60_2475 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH60_2478 ENOG4105DAN ATP-dependent protease CH60_248 ENOG4108SIC Transcriptional regulator CH60_2480 ENOG4108RS6 transposase CH60_2482 ENOG4105PAN UPF0352 protein CH60_2483 ENOG4105E68 Sulfatase CH60_2486 ENOG4105GMB type VI secretion system effector, hcp1 family CH60_2492 ENOG4105C1J atp-dependent rna helicase CH60_2493 ENOG4108RS6 transposase CH60_2495 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) CH60_2497 ENOG41061WM D-Alanyl-D-Alanine CH60_2498 ENOG4105CXG d-lactate dehydrogenase CH60_2500 ENOG4105N1F Hnh endonuclease CH60_2502 ENOG4105Y3U Transglycosylase-associated protein CH60_2504 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein CH60_2507 ENOG4108W15 Protein of unknown function (DUF1456) CH60_2509 ENOG4105C32 Amino acid ABC transporter (Permease) CH60_2510 ENOG4105CNN ABC, transporter CH60_2511 ENOG4108JJB ABC transporter CH60_2512 ENOG4108IV0 ABC, transporter CH60_2515 ENOG4105KHC sulfurtransferase CH60_2518 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component CH60_2519 ENOG4108IJ8 ABC transporter CH60_2520 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component CH60_2521 ENOG4105D5Q Arginine ornithine antiporter CH60_2522 ENOG4105CXN decarboxylase CH60_2524 ENOG4105FDR Membrane CH60_2526 ENOG4105DVT helicase CH60_2527 ENOG4105CH6 catalase CH60_2528 ENOG4108UII YfaZ family CH60_2529 ENOG4105E0U tyrosine-specific transport protein CH60_2532 ENOG4105XPH Ferredoxin CH60_2533 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH60_2534 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH60_2536 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH60_2537 ENOG4105BZU Histidine kinase CH60_2538 ENOG41068CG regulatoR CH60_2539 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC CH60_2540 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC CH60_2541 ENOG4106UW1 Major Facilitator superfamily CH60_2543 ENOG4105FCK Membrane CH60_2546 ENOG4107R6D beta-lactam binding protein AmpH CH60_2547 ENOG4105CT4 transporter CH60_2549 ENOG4105C8Q Methyl-accepting chemotaxis CH60_2551 ENOG4105Y50 Virulence Protein CH60_2553 ENOG4105HRS Antitermination protein CH60_2554 ENOG4105G63 Type III effector Hrp-dependent CH60_2556 ENOG4105MVE transcriptional regulator CH60_2557 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) CH60_2561 ENOG4105TKZ Tail Sheath CH60_2569 ENOG4108T86 baseplate J family protein CH60_2573 ENOG4108Q3X Transcriptional regulator CH60_2575 ENOG4105CS2 ec 3.2.1.21 CH60_2581 ENOG4105EQR Transposase IS116 IS110 IS902 CH60_2582 ENOG4105C1J atp-dependent rna helicase CH60_2583 ENOG4107MVR Transcriptional regulator CH60_2585 ENOG4105CJ1 ABC, transporter CH60_2586 ENOG4107QWP ABC-2 type transporter CH60_2587 ENOG4107QWP ABC-2 type transporter CH60_2590 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CH60_2592 ENOG4105BZU Histidine kinase CH60_2594 ENOG4105EAA nucleoside CH60_2595 ENOG4108RS6 transposase CH60_2596 ENOG4105EAA nucleoside CH60_2597 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) CH60_2599 ENOG4105CN8 Transcriptional regulator CH60_2600 ENOG4105C94 Transporter CH60_2604 ENOG4108RS6 transposase CH60_2605 ENOG4105HFZ Membrane CH60_2606 ENOG4108ZAF Molybdopterin CH60_2607 ENOG4105M00 molybdopterin converting factor, subunit 1 CH60_2609 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) CH60_2611 ENOG4105CHW UPF0052 protein CH60_2615 ENOG4105CHW UPF0052 protein CH60_2616 ENOG4105VYA Uncharacterized conserved protein (DUF2132) CH60_2617 ENOG4105CCW damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity) CH60_2618 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CH60_2619 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CH60_2620 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CH60_2625 ENOG4108K4B hydrolase CH60_2627 ENOG4105E0C molybdate abc transporter CH60_2628 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein CH60_2629 ENOG410680R Protein of unknown function (DUF2592) CH60_263 ENOG4105C0A alcohol dehydrogenase CH60_2630 ENOG4105F4R Transcriptional regulator mode CH60_2631 ENOG4105DKW ABC transporter CH60_2634 ENOG4105CMR udp-glucose 4-epimerase CH60_2635 ENOG4105F0Z galactose-1-phosphate uridylyltransferase CH60_2638 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) CH60_2641 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CH60_2643 ENOG4105PGM cation diffusion facilitator family transporter CH60_2644 ENOG4106Z1T Nicotinamide Mononucleotide Transporter CH60_2649 ENOG4105UFD tol-pal system protein YbgF CH60_265 ENOG4108UUM single-stranded DNA-binding protein CH60_2650 ENOG4105KCK Peptidoglycan-associated lipoprotein CH60_2652 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CH60_2652 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CH60_2653 ENOG4105M8F Biopolymer transport protein exbD tolR CH60_2654 ENOG4105E02 MotA TolQ exbB proton channel CH60_2655 ENOG4107YD3 Thioesterase CH60_2656 ENOG4105KJB cyd operon protein YbgE CH60_2658 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CH60_2659 ENOG4105C4M (Ubiquinol oxidase) subunit I CH60_266 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CH60_2660 ENOG4108RS6 transposase CH60_2661 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha CH60_2663 ENOG4105C7S Dehydrogenase CH60_2664 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 CH60_2665 ENOG4105E33 succinate dehydrogenase CH60_2667 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein CH60_2668 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit CH60_2669 ENOG4105BZN citrate synthase CH60_267 ENOG4105MSB protein, conserved in bacteria CH60_2671 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) CH60_2672 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) CH60_2673 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CH60_2675 ENOG4108Z1B Cyclase dehydrase CH60_2677 ENOG4108RS6 transposase CH60_2678 ENOG4105DFP Integrase CH60_268 ENOG4105CGF Aromatic amino acid aminotransferase CH60_2688 ENOG4105VUH addiction module killer protein CH60_269 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CH60_2692 ENOG4105BZU Histidine kinase CH60_2694 ENOG4105DHI Methyltransferase CH60_2695 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CH60_2696 ENOG4105VEQ Cold shock protein CH60_2699 ENOG4105C85 amino acid CH60_270 ENOG4105CDU Replicative dna helicase CH60_2702 ENOG41064PC CH60_2703 ENOG4105TIK CH60_2704 ENOG4105N4N Protein of unknown function (DUF2766) CH60_2708 ENOG4105BZ1 (ABC) transporter CH60_271 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein CH60_2714 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) CH60_2718 ENOG4108TSE Transferase CH60_2719 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit CH60_272 ENOG4105P4Z Phage shock protein G CH60_2721 ENOG4105CG6 trap dicarboxylate transporter dctm subunit CH60_2722 ENOG4108KX4 response regulator CH60_2724 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme CH60_2728 ENOG4105UQX Mate efflux family protein CH60_273 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CH60_2732 ENOG4105DIA mandelate racemase muconate lactonizing CH60_2734 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr CH60_2735 ENOG4105KIR Thiol-disulfide oxidoreductase dcc CH60_2736 ENOG4105CSP Major Facilitator Superfamily CH60_2737 ENOG4105TNG K13735 adhesin invasin CH60_274 ENOG4105MYN Zinc uptake regulation protein CH60_2741 ENOG4105CJB Exodeoxyribonuclease I CH60_2742 ENOG4105CUB amino acid CH60_2744 ENOG4107SCQ Iron-containing alcohol dehydrogenase CH60_2745 ENOG4105C2J ABC transporter CH60_2750 ENOG4108535 NAD dependent epimerase/dehydratase family CH60_2752 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) CH60_2754 ENOG4105ECC imidazole-glycerol-phosphate dehydratase CH60_2755 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) CH60_2758 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase CH60_2759 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) CH60_276 ENOG41080IJ Diacylglycerol kinase CH60_2760 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CH60_2761 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CH60_2762 ENOG4105DUU IucA IucC family protein CH60_2763 ENOG4105CNM Receptor CH60_2764 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) CH60_2765 ENOG4105DQ5 transport system permease protein CH60_2766 ENOG4105TVJ transport system, permease CH60_2767 ENOG4105E0A ABC, transporter CH60_2768 ENOG4105DUU IucA IucC family protein CH60_2770 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) CH60_2771 ENOG4105DY8 decarboxylase CH60_2772 ENOG4108819 ferric iron reductase CH60_2773 ENOG4105EE5 Membrane protein terC CH60_2774 ENOG4108GAE asmA family CH60_2777 ENOG4105D1F ATP-binding protein CH60_2779 ENOG4108RS6 transposase CH60_2783 ENOG4105E5W Transporter CH60_2785 ENOG41067MG lrgb family CH60_2788 ENOG4107GZ4 SanA protein CH60_2789 ENOG4108HWV )-transporter CH60_2792 ENOG4105DHF Membrane CH60_2794 ENOG4105CBP Major Facilitator CH60_2795 ENOG4105EGI Transcriptional regulator CH60_28 ENOG4107H3J ribonuclease CH60_2800 ENOG4105ENT Efflux transporter rnd family, mfp subunit CH60_2801 ENOG4105C19 ABC transporter CH60_2803 ENOG4105CVM Molybdenum cofactor synthesis domain protein CH60_2804 ENOG4105D06 uba thif-type nad fad binding protein CH60_2807 ENOG4105C5H ABC transporter CH60_2827 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH60_2837 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CH60_2838 ENOG41062T2 Acyl carrier protein CH60_284 ENOG4108S1B Periplasmic chaperone protein CH60_2840 ENOG4105CHR reductase CH60_2841 ENOG4108KQ6 Enoyl-CoA hydratase CH60_2843 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase CH60_2844 ENOG4105CHR reductase CH60_2845 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CH60_2846 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) CH60_2853 ENOG4108BUD transposase CH60_2855 ENOG4108Z0T Part of a sulfur-relay system (By similarity) CH60_2859 ENOG4105K4P CoA-binding domain protein CH60_2860 ENOG4108Q67 UPF0319 protein CH60_2862 ENOG41088T4 Helicase IV CH60_2863 ENOG410901E Membrane CH60_2864 ENOG4105EM2 membrane CH60_2865 ENOG4108RZ1 DNA transformation protein CH60_2867 ENOG4105UYK outer membrane protein a CH60_2868 ENOG4108RS6 transposase CH60_2870 ENOG4105CFI type iii restriction protein res subunit CH60_2871 ENOG4105I08 Pseudouridine synthase CH60_2872 ENOG4105C2C drug resistance transporter, Bcr CflA CH60_2873 ENOG4105HG6 CH60_2874 ENOG4108JQ5 ABC transporter CH60_2875 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component CH60_2876 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component CH60_2877 ENOG4105E43 Extracellular solute-binding protein, family 5 CH60_2878 ENOG4105CXC rtn protein CH60_2880 ENOG4107TT5 NLP P60 protein CH60_2881 ENOG41076MN Phosphoesterase, PA-phosphatase related CH60_2882 ENOG4105CKI cobalamin synthesis protein CH60_2884 ENOG4107YCY Transcriptional regulator CH60_2885 ENOG4105DEI Mannitol dehydrogenase CH60_2886 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) CH60_2889 ENOG4105KRS Proteinase inhibitor CH60_2890 ENOG4105CHR reductase CH60_2893 ENOG4105C26 Dehydrogenase CH60_2895 ENOG4105E66 phosphoriboisomerase A CH60_2897 ENOG4105C2J ABC transporter CH60_2898 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane CH60_29 ENOG41066T0 asmA family CH60_2900 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein CH60_2901 ENOG4105DE4 1-phosphofructokinase CH60_2902 ENOG4105DM4 PTS System CH60_2903 ENOG4108SGD regulatory protein CH60_2906 ENOG4108UIF Chaperone CH60_2907 ENOG4108D1K outer membrane usher protein CH60_2911 ENOG4105CHF Glutathione S-transferase CH60_2912 ENOG4108VBZ doxx family CH60_2914 ENOG41090KG Inner membrane protein YqjE CH60_2915 ENOG4105NE1 Conserved Protein CH60_2918 ENOG4106W5V Membrane CH60_2921 ENOG4105DPW Major facilitator superfamily MFS_1 CH60_2923 ENOG4107QZW Altronate oxidoreductase CH60_2924 ENOG4105CTX dehydratase CH60_2925 ENOG4105P66 Membrane CH60_2926 ENOG4108RS6 transposase CH60_2929 ENOG4105EE0 oxidoreductase CH60_2930 ENOG4108VKG metal-dependent hydrolase CH60_2934 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CH60_2935 ENOG4108YK4 Acid-resistance membrane protein CH60_2938 ENOG4108M24 von Willebrand factor, type A CH60_2941 ENOG4108M24 von Willebrand factor, type A CH60_2942 ENOG4105D5K Hemolysin activator protein CH60_2943 ENOG4105CKT filamentous hemagglutinin CH60_2945 ENOG4105CKT filamentous hemagglutinin CH60_2947 ENOG4105CKT filamentous hemagglutinin CH60_2952 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 CH60_2953 ENOG4107KJX Transcriptional regulator CH60_2954 ENOG4108IJG ABC transporter substrate-binding protein CH60_2956 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component CH60_2958 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CH60_296 ENOG4105DAX Pfam:DUF2983 CH60_2960 ENOG4108MI0 Resistance protein CH60_2961 ENOG4105J12 Multidrug resistance protein mdtN CH60_2964 ENOG4105CHM Aminotransferase CH60_2968 ENOG4105KME endoribonuclease L-psp CH60_2985 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH60_2986 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) CH60_2987 ENOG4105VCC 30S ribosomal protein S21 CH60_2990 ENOG4107ZVW dihydroneopterin aldolase CH60_2993 ENOG4106MWK domain protein CH60_2994 ENOG4105I7R Adenylate cyclase CH60_2997 ENOG4105DVH amino acid CH60_2998 ENOG4105W0Z cytoplasmic protein CH60_30 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) CH60_300 ENOG4105D4P Coproporphyrinogen iii oxidase CH60_3001 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b CH60_3002 ENOG4106032 Glutathionylspermidine synthase CH60_3005 ENOG4105DFG type I secretion outer membrane protein CH60_3006 ENOG41087AY ADP-Ribose pyrophosphatase CH60_3007 ENOG4108SX3 cytoplasmic protein CH60_3008 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) CH60_3009 ENOG4105IPS esterase CH60_301 ENOG41090JE Utilization Protein CH60_3010 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH60_3011 ENOG4105CR8 Transcriptional regulator CH60_3012 ENOG4105NF4 modulator of drug activity CH60_3013 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH60_3014 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase CH60_3015 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) CH60_3018 ENOG4105CV8 reductase CH60_3019 ENOG4108I6A alcohol dehydrogenase CH60_3020 ENOG4105CF7 AraC family transcriptional regulator CH60_3021 ENOG4108K81 inner membrane protein YghB CH60_3022 ENOG4105C28 cystathionine CH60_3023 ENOG4105CWK Biopolymer transport protein, ExbB CH60_3025 ENOG4108ZZF transport protein (ExbD) CH60_303 ENOG4107F3C Hemin uptake protein CH60_3039 ENOG4108RS6 transposase CH60_304 ENOG4107ENK receptor CH60_3040 ENOG4106PG1 outer membrane usher protein CH60_3041 ENOG4106P2F Pfam:Pili_assembly_C CH60_3043 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein CH60_3048 ENOG4105D00 flagellar biosynthetic protein flhB CH60_3049 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CH60_305 ENOG4106QJH hemin transport protein CH60_3050 ENOG4105VS8 Flagellar biosynthetic protein fliq CH60_3051 ENOG4105CN7 Flagellar biosynthetic protein FliP CH60_3052 ENOG4105DD5 Flagellar motor switch protein CH60_3054 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CH60_3056 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CH60_3059 ENOG4108JIR Flagellum-specific ATP synthase CH60_306 ENOG4107R4I Periplasmic binding protein CH60_3063 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA CH60_3064 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CH60_3065 ENOG4108ZC9 flagellar basal-body rod protein flgc CH60_3066 ENOG4105W00 Flagellar hook capping protein CH60_3067 ENOG4105BZE flagellar hook protein, FlgE CH60_3068 ENOG4108KPB Flagellar basal-body rod protein FlgF CH60_3069 ENOG4105CGA flagellar basal-body rod protein FlgG CH60_307 ENOG4105EHG Permease protein CH60_3070 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) CH60_3071 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) CH60_3073 ENOG4105E1Q flagellar hook-associated protein CH60_3077 ENOG4108M3R transcriptional activator CadC CH60_3082 ENOG4105I03 Flagellin CH60_3084 ENOG410804A Flagellar hook-associated 2 domain-containing protein CH60_309 ENOG4105C28 cystathionine CH60_3090 ENOG4107RD7 Flagellar Motor Protein, MotA CH60_3095 ENOG4108XTF Outer Membrane Lipoprotein CH60_3096 ENOG4108XTF Outer Membrane Lipoprotein CH60_3099 ENOG4105DQ6 Transposase CH60_31 ENOG4105CMB EAL domain-containing protein CH60_310 ENOG4105C44 Serine transporter CH60_3103 ENOG4108WC9 type VI secretion system effector, hcp1 family CH60_3105 ENOG4107W52 maltose operon periplasmic protein CH60_3109 ENOG4107FKK extracellular solute-binding protein family 1 CH60_311 ENOG4105EQ2 LysR family Transcriptional regulator CH60_3110 ENOG4105D56 permease protein CH60_3111 ENOG4105EG2 ABC transporter, permease CH60_3114 ENOG4105CFH Aspartokinase CH60_3117 ENOG4105C3R Methionine synthase CH60_3118 ENOG41069M3 Transcriptional regulator CH60_312 ENOG4105KSU Redox protein CH60_3120 ENOG4108I9X Isocitrate lyase CH60_3121 ENOG4107QP3 malate synthase g CH60_313 ENOG41066VF YeeE YedE family protein CH60_3136 ENOG4105C12 Phosphoribosylglycinamide synthetase CH60_3137 ENOG4108T8B Protein of unknown function (DUF1481) CH60_3139 ENOG4105R2J Conserved Protein CH60_314 ENOG4108IUF type iii secretion CH60_3140 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) CH60_3145 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) CH60_3147 ENOG4105D06 uba thif-type nad fad binding protein CH60_315 ENOG4108TN6 type iii secretion CH60_3150 ENOG4105D41 biosynthesis protein thiH CH60_3158 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) CH60_3159 ENOG4105PM1 preprotein translocase subunit SecE CH60_316 ENOG41083GP type iii secretion CH60_3168 ENOG4108RS6 transposase CH60_3169 ENOG4105CBG Sulfatase CH60_317 ENOG4108HHI Type III secretion system protein CH60_3170 ENOG4105E98 transcriptional regulator DeoR family CH60_3171 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of CH60_3172 ENOG4105E70 isomerase CH60_3173 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB CH60_3174 ENOG4105ETZ PTS System CH60_3175 ENOG4105F3R pts system mannose fructose sorbose family iid CH60_3176 ENOG4108YTN IIa component CH60_3177 ENOG4105CE4 GlcNAc 6-P deacetylase CH60_3178 ENOG4105CHR reductase CH60_318 ENOG41063Q7 Type III secretion system protein CH60_3180 ENOG4105C4X radical SAM domain protein CH60_3181 ENOG4105ENH Sulfatase CH60_3183 ENOG4105D2N Aldolase CH60_3186 ENOG4105ETE Transcriptional regulator (LacI family CH60_3187 ENOG4105DPW Major facilitator superfamily MFS_1 CH60_3189 ENOG4105ETE Transcriptional regulator (LacI family CH60_3191 ENOG4105CI1 PTS System CH60_3192 ENOG4105C4C beta-galactosidase CH60_3194 ENOG4105EG2 ABC transporter, permease CH60_3196 ENOG4107FKK extracellular solute-binding protein family 1 CH60_3199 ENOG4105CNN ABC, transporter CH60_32 ENOG4105VSH 4-oxalocrotonate tautomerase CH60_3200 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH60_3202 ENOG4108UY0 (LipO)protein CH60_3203 ENOG4105NTW Transcriptional regulator CH60_321 ENOG4108JIR Flagellum-specific ATP synthase CH60_3220 ENOG4105WJ3 XRE family Transcriptional regulator CH60_3221 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation CH60_3225 ENOG4105DFP Integrase CH60_3229 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) CH60_3230 ENOG4105T95 Thiol disulfide interChange protein CH60_3231 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CH60_3232 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) CH60_3233 ENOG4105CT7 inner membrane cred family protein CH60_3234 ENOG4105EB3 Histidine kinase CH60_3235 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH60_3236 ENOG4105Y75 tpr repeat protein CH60_3239 ENOG4108UT2 hemolysin iii CH60_3247 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CH60_3248 ENOG4105D0A hydroxylase CH60_3249 ENOG4107RAQ aminopeptidase CH60_3252 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase CH60_3253 ENOG4108JQ1 Dehydrogenase CH60_3254 ENOG4105E66 phosphoriboisomerase A CH60_3256 ENOG4105MPN Membrane CH60_3258 ENOG4105D64 Mechanosensitive ion channel CH60_3259 ENOG4105D2N Aldolase CH60_3262 ENOG4108RS6 transposase CH60_3263 ENOG4105CV1 Transketolase (EC 2.2.1.1) CH60_3264 ENOG4108K0D peptidase, M48 CH60_3266 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) CH60_3270 ENOG4105RWS endonuclease I CH60_3271 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) CH60_3272 ENOG4105D7Z glutathione synthase CH60_3275 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) CH60_3277 ENOG4105CZX twitching motility protein CH60_3278 ENOG4105DFA alanine racemase domain protein CH60_3279 ENOG4105II7 pyrroline-5-carboxylate reductase CH60_3280 ENOG4108VIA integral membrane protein CH60_3282 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) CH60_3283 ENOG4105CSA Coproporphyrinogen iii oxidase CH60_3287 ENOG4105EUK rtx toxin RtxA CH60_3288 ENOG4105K33 Periplasmic Protein CH60_3289 ENOG4105K33 Periplasmic Protein CH60_3290 ENOG4105CSV Glutaminase CH60_3291 ENOG41090ED Protein with unknown function (DUF469) CH60_3293 ENOG4105CEN a g-specific adenine glycosylase CH60_3298 ENOG4105CNN ABC, transporter CH60_3299 ENOG4105C2J ABC transporter CH60_33 ENOG4107SS6 2-dehydro-3-deoxygluconokinase CH60_3300 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH60_3301 ENOG4105CXN decarboxylase CH60_3316 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH60_333 ENOG4105BZU Histidine kinase CH60_3337 ENOG4105DUU IucA IucC family protein CH60_3338 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) CH60_334 ENOG4105WH1 Two component transcriptional regulator luxr family CH60_3340 ENOG4105CT4 transporter CH60_3342 ENOG4105ETE Transcriptional regulator (LacI family CH60_3343 ENOG4105C8P )-transporter CH60_3344 ENOG41062WK cellular response to acidity CH60_3346 ENOG4105CNA YD repeat protein CH60_3348 ENOG4105CS6 Rhs element vgr protein CH60_335 ENOG4105CK2 sodium dicarboxylate symporter CH60_3352 ENOG4107EFN gluconate transport system permease 3 CH60_3356 ENOG4105BZ1 (ABC) transporter CH60_3362 ENOG4105C0W non-ribosomal peptide synthetase CH60_3364 ENOG4105C0W non-ribosomal peptide synthetase CH60_3365 ENOG4107ZSV Receptor CH60_3366 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) CH60_337 ENOG41062QD Membrane CH60_3370 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) CH60_3371 ENOG4105CFC Transporter CH60_3379 ENOG4105C1P efflux transporter, rnd family, mfp subunit CH60_3380 ENOG4105BZU Histidine kinase CH60_3381 ENOG4105DQ6 Transposase CH60_3389 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH60_3396 ENOG4105CS6 Rhs element vgr protein CH60_3399 ENOG4105CNA YD repeat protein CH60_34 ENOG4105CS0 peptidase CH60_3405 ENOG4105CS6 Rhs element vgr protein CH60_3407 ENOG4105CNA YD repeat protein CH60_3410 ENOG4107TYG Oxidoreductase domain-containing protein CH60_3411 ENOG4105W4W Transcriptional regulator CH60_3412 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) CH60_3413 ENOG4108RVA ribokinase CH60_3414 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CH60_3419 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component CH60_3422 ENOG4105C7N Xanthine uracil vitamin C permease CH60_3423 ENOG4105EEQ Na H antiporter CH60_3425 ENOG4105D1S lipid A biosynthesis CH60_3427 ENOG4105C2J ABC transporter CH60_3428 ENOG4105CNN ABC, transporter CH60_3430 ENOG4105EF1 ribulokinase CH60_3431 ENOG4105C2X Arabinose 5-phosphate isomerase CH60_3432 ENOG4105CYM Glutathione S-transferase CH60_3435 ENOG4108RS6 transposase CH60_3436 ENOG4105VEQ Cold shock protein CH60_3437 ENOG4105VEQ Cold shock protein CH60_3438 ENOG4108XTF Outer Membrane Lipoprotein CH60_344 ENOG4105EHE chorismate mutase- prephenate dehydrogenase CH60_3441 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase CH60_3442 ENOG4105CSH Transporter CH60_3445 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) CH60_3446 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CH60_3448 ENOG4108IA2 Sodium pantothenate symporter CH60_3449 ENOG4105RG0 Membrane CH60_345 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CH60_3451 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CH60_3452 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein CH60_3455 ENOG4105CCD The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity) CH60_3456 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family CH60_3457 ENOG41062P1 Diguanylate cyclase phosphodiesterase CH60_3458 ENOG4105DFF Rod shape-determining protein mreb CH60_3459 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) CH60_346 ENOG4108NEV two component transcriptional regulator, LytTR family CH60_3460 ENOG4105VQ7 Rod shape-determining protein MreD CH60_3462 ENOG4105C03 ribonuclease CH60_3463 ENOG4105QD6 exported protein CH60_3465 ENOG4105D1U peptidase U62 modulator of DNA gyrase CH60_347 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CH60_3475 ENOG4105CR8 Transcriptional regulator CH60_3479 ENOG4105C26 Dehydrogenase CH60_348 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CH60_3482 ENOG4105UNR (Barnase) inhibitor CH60_3484 ENOG4105CMS peptidase U62, modulator of DNA gyrase CH60_3486 ENOG4108XVM Cytochrome b(562) CH60_3487 ENOG4105NXH GreA GreB family elongation factor CH60_3488 ENOG4105CG3 alpha amylase, catalytic region CH60_3489 ENOG4105C5Y PTS System CH60_349 ENOG4108NE3 Salt-induced outer membrane protein CH60_3490 ENOG4105D4X repressor CH60_3492 ENOG4105KME endoribonuclease L-psp CH60_3495 ENOG41080Z8 PHOSPHOCARRIER protein CH60_3497 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN CH60_3498 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA CH60_3499 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH60_3500 ENOG4108IUZ ABC transporter CH60_3501 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA CH60_3502 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) CH60_3503 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase CH60_3504 ENOG4105C2X Arabinose 5-phosphate isomerase CH60_3505 ENOG4105FEU K -dependent Na -Ca exchanger CH60_3506 ENOG4105DHJ ABC, transporter CH60_3507 ENOG4105CY3 ABC transporter, permease CH60_3508 ENOG4107PE3 Mammalian cell entry related domain protein CH60_3509 ENOG4105E3I toluene tolerance CH60_3510 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane CH60_3511 ENOG4105VFK BolA family CH60_3513 ENOG4105C0H protease CH60_3514 ENOG4108RS6 transposase CH60_3516 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CH60_3523 ENOG4105S8Q sugar efflux transporter CH60_3526 ENOG4105DP9 ABC transporter CH60_3527 ENOG4106SMU thiamine transporter membrane protein CH60_3529 ENOG4108KF1 Membrane CH60_3530 ENOG4105CQ2 DNA polymerase CH60_354 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY CH60_3543 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH60_355 ENOG4106KVJ cytochrome C assembly protein CH60_3552 ENOG4105D3G Pseudouridine synthase CH60_3553 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) CH60_3555 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) CH60_3556 ENOG4105CEZ Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity) CH60_356 ENOG4108JU6 CBS domain protein CH60_3561 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) CH60_3563 ENOG4105DWK Membrane CH60_3564 ENOG4105N14 lysine exporter protein LysE YggA CH60_3565 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain CH60_3566 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain CH60_3568 ENOG4108RS6 transposase CH60_3570 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase CH60_3573 ENOG4105DTN riboflavin biosynthesis protein ribF CH60_3575 ENOG41063Z6 transcriptional regulator, lysR family CH60_3579 ENOG4106HK8 GPR1 FUN34 yaaH family protein CH60_358 ENOG4105D9M gamma-glutamylcysteine synthetase CH60_3582 ENOG4108RIR Molybdenum cofactor biosynthesis protein CH60_359 ENOG4105W39 Membrane CH60_3592 ENOG41065U4 response regulator CH60_3593 ENOG4108RH0 Crea protein CH60_3596 ENOG4105UEI Transcriptional Regulator AraC Family CH60_3597 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) CH60_3599 ENOG4107SC1 transglycosylase CH60_360 ENOG4107VXZ Hydrolase CH60_3602 ENOG4108KHX Diguanylate cyclase CH60_3603 ENOG41090EK ompa motb domain protein CH60_3604 ENOG4105C5H ABC transporter CH60_3606 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase CH60_3607 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) CH60_3608 ENOG4105EAC phosphoserine phosphatase CH60_3609 ENOG41062Z9 Membrane CH60_3613 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CH60_3614 ENOG4105D9N nucleoside CH60_3615 ENOG4105EYA deoxyribonuclease CH60_3616 ENOG4108NRW Phospholipase, patatin family CH60_3618 ENOG4105K3G Periplasmic Protein CH60_3620 ENOG4105KEG ribosomal-protein-alanine acetyltransferase CH60_3621 ENOG4108WPU DNA polymerase III subunit psi CH60_3624 ENOG4105YBH Protein of unknown function (DUF1435) CH60_3625 ENOG4105BZU Histidine kinase CH60_3628 ENOG4105BZS acriflavin resistance protein CH60_3629 ENOG410624X efflux transporter, rnd family, mfp subunit CH60_3632 ENOG4105DKP glycosyl transferase, family 9 CH60_3634 ENOG4105DKT Transcriptional regulator CH60_3641 ENOG4105RI1 glycoprotein receptor CH60_3642 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) CH60_3643 ENOG4105DM4 PTS System CH60_3644 ENOG4108YRF PTS System CH60_3645 ENOG4106R3P AraC family transcriptional regulator CH60_3646 ENOG4108XCZ PTS System CH60_3648 ENOG4108M3P Membrane CH60_365 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) CH60_3658 ENOG4105CMM transposase CH60_366 ENOG4105CIM Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity) CH60_3660 ENOG4105FBQ ATPase associated with various cellular activities aaa_5 CH60_3665 ENOG4105M6F mutator MutT protein CH60_3670 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) CH60_3671 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) CH60_3672 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) CH60_3676 ENOG4105CNI cell division protein FtsW CH60_3679 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) CH60_3680 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CH60_3681 ENOG4105CJN penicillin-binding protein CH60_3682 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) CH60_3685 ENOG4108RNS Exports L-alanine (By similarity) CH60_3686 ENOG4107B7Y DNA-binding transcriptional regulator FruR CH60_3687 ENOG4108RS6 transposase CH60_3688 ENOG4108ZP8 Acetolactate synthase small subunit CH60_3689 ENOG4105C7K acetolactate synthase CH60_3690 ENOG4108IQE Amp-dependent synthetase and ligase CH60_3691 ENOG41064T2 transcriptional regulator, lysR family CH60_3693 ENOG4108RS6 transposase CH60_3694 ENOG4105C0H protease CH60_3695 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III CH60_3696 ENOG4105D6Z AFG1 family ATPase CH60_3699 ENOG4107MKT Stringent starvation protein a CH60_3700 ENOG4105KB2 stringent starvation protein b CH60_3702 ENOG4105BZ8 glutamate synthase CH60_3703 ENOG4105CBC glutamate synthase CH60_3704 ENOG4105N5T Radical SAM Protein CH60_3705 ENOG4105BZU Histidine kinase CH60_3706 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain CH60_3708 ENOG4105W4M Transport-associated protein CH60_3712 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) CH60_3713 ENOG4108CNN domain protein CH60_3714 ENOG4105CWB LysR family transcriptional Regulator CH60_3715 ENOG4105CHF Glutathione S-transferase CH60_3720 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) CH60_3722 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) CH60_3724 ENOG4105JC1 sterol-binding domain protein CH60_3726 ENOG4105CGY Dna recombination protein CH60_3727 ENOG4108KF1 Membrane CH60_373 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) CH60_3730 ENOG4108I5U Uridine phosphorylase CH60_3731 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) CH60_3733 ENOG4105EMK carboxylate amino acid amine transporter CH60_3734 ENOG4105DZ2 Transcriptional regulator CH60_3735 ENOG4105RK9 auxin efflux carrier CH60_3736 ENOG4107T6V glycerophosphoryl diester phosphodiesterase CH60_374 ENOG4108IUS Transketolase CH60_3748 ENOG4108IV0 ABC, transporter CH60_3749 ENOG4105C0Z ABC transporter CH60_375 ENOG4108HHA Transketolase CH60_3750 ENOG4105CF8 branched-chain amino acid ABC transporter, permease CH60_3751 ENOG4105C32 Amino acid ABC transporter (Permease) CH60_3752 ENOG4105CP9 extracellular ligand-binding receptor CH60_3753 ENOG4105U59 -acetyltransferase CH60_3754 ENOG4108RS6 transposase CH60_3756 ENOG4105CRP Part of the ABC transporter FtsEX involved in CH60_3757 ENOG4105CAK Cell division ATP-binding protein ftsE CH60_3758 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CH60_3758 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CH60_3759 ENOG4106H78 methyltransferase CH60_376 ENOG4105CNN ABC, transporter CH60_3760 ENOG4105MG3 Membrane CH60_3763 ENOG4107FS9 Membrane CH60_3766 ENOG4105EX9 Membrane CH60_3767 ENOG4108W1V Lipoprotein CH60_3768 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CH60_377 ENOG4105C2J ABC transporter CH60_3770 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A CH60_3771 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase CH60_3773 ENOG4105DQF Hydrolase CH60_3774 ENOG4108EUD Lysophospholipase CH60_3776 ENOG4105CCF Lysine exporter protein (Lyse ygga) CH60_3777 ENOG4105C9U ATP-dependent DNA helicase RecQ CH60_3778 ENOG4105HDD phospholipase CH60_3779 ENOG4108VUY thioesterase Superfamily protein CH60_3780 ENOG4105FR1 rard protein CH60_3781 ENOG4107QUT magnesium and cobalt transport protein CorA CH60_3783 ENOG4105EQN UPF0261 protein CH60_3785 ENOG4105C4R Atp-dependent dna helicase CH60_3786 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant CH60_3787 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CH60_3788 ENOG4105CT0 Protein of unknown function, DUF484 CH60_3790 ENOG4105S7Z (LipO)protein CH60_3792 ENOG4107T0K Adenylate cyclase CH60_3794 ENOG41076E6 Uroporphyrinogen-III Synthase CH60_3795 ENOG4105ECF c-methyltransferase CH60_3796 ENOG410601J HemY protein CH60_3797 ENOG4108RS6 transposase CH60_3803 ENOG4105C85 amino acid CH60_3807 ENOG4105EGZ biosynthesis protein CH60_3808 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CH60_3809 ENOG4108WJ1 acetyltransferase CH60_381 ENOG4108XVM Cytochrome b(562) CH60_3810 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) CH60_3811 ENOG4105C1B dTDP-glucose 4-6-dehydratase CH60_3812 ENOG4108IJ1 Dehydrogenase CH60_3813 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase CH60_3814 ENOG4105SFE lipopolysaccharide biosynthesis protein CH60_3815 ENOG4105ESV Glycosyl transferase, family 4 CH60_3817 ENOG4105K63 Thioredoxin CH60_382 ENOG4105CPW cytochrome b561 CH60_3820 ENOG4105C4R Atp-dependent dna helicase CH60_3821 ENOG4105KQ5 peptidylprolyl cis-trans isomerase CH60_3824 ENOG4105GQR Chaperone CH60_3825 ENOG4105CW0 outer membrane usher protein CH60_3827 ENOG4108VEV chaperone CH60_383 ENOG4108NEM leader-binding protein dmsD CH60_3834 ENOG4105EMY transcriptional regulator CH60_384 ENOG4107KGK dmso reductase anchor subunit CH60_3840 ENOG4105C7B Threonine dehydratase CH60_3842 ENOG4105CM2 brancheD-chain amino acid aminotransferase CH60_3843 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit CH60_3845 ENOG4105C0P Mg chelatase subunit ChlI CH60_3846 ENOG4108WFC UPF0438 protein yifE CH60_3847 ENOG41062B0 ABC transporter, permease CH60_3849 ENOG4107R9N ABC transporter CH60_385 ENOG4105QAX Iron-sulfur CH60_3850 ENOG4105C2J ABC transporter CH60_3851 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator CH60_386 ENOG4107QY8 reductase CH60_3862 ENOG4108Y73 Membrane CH60_3864 ENOG4105C5Q Transcriptional regulator CH60_3866 ENOG4105EHV domain protein CH60_3867 ENOG4107QN2 dihydrolipoyl dehydrogenase CH60_3868 ENOG4105YHG TonB family CH60_3869 ENOG4107QZV Type I secretion membrane fusion protein CH60_387 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CH60_3872 ENOG4105X58 receptor CH60_3876 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase CH60_388 ENOG4105E98 transcriptional regulator DeoR family CH60_3880 ENOG4105DQ6 Transposase CH60_3886 ENOG4105D13 transposase CH60_3891 ENOG4108MG3 formate dehydrogenase CH60_3892 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CH60_3893 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CH60_3894 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CH60_3896 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CH60_3897 ENOG4105C8Q Methyl-accepting chemotaxis CH60_39 ENOG4108PU9 oligogalacturonate-specific porin CH60_390 ENOG4105C2J ABC transporter CH60_3901 ENOG4108YYI Protein of unknown function (DUF2810) CH60_3903 ENOG4105E61 Mannitol repressor protein CH60_3905 ENOG4105CTS PTS system mannitol-specific CH60_3906 ENOG4106JH6 (LipO)protein CH60_391 ENOG4105CNN ABC, transporter CH60_3910 ENOG4108R3E Dna-3-methyladenine glycosylase i CH60_3912 ENOG4108ZG0 Ompa motb domain protein CH60_3915 ENOG4107T9C Alpha amylase catalytic region CH60_3917 ENOG4105JKW Valine--pyruvate aminotransferase CH60_392 ENOG4105F5R ABC transporter CH60_3921 ENOG4105R2A (LipO)protein CH60_3922 ENOG4105D99 atp gtp-binding protein CH60_3923 ENOG4105D99 atp gtp-binding protein CH60_3924 ENOG4105C7B Threonine dehydratase CH60_3928 ENOG4105DQ6 Transposase CH60_3929 ENOG410667J hydrolase CH60_393 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase CH60_3930 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CH60_3931 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) CH60_3932 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CH60_3935 ENOG4105VG0 50S ribosomal protein l34 CH60_3938 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins CH60_394 ENOG4105CMG Carbohydrate kinase CH60_3943 ENOG4105C7N Xanthine uracil vitamin C permease CH60_3944 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 CH60_3945 ENOG4105DRP amino acid AbC transporter CH60_3946 ENOG4105EAD ABC transporter CH60_3947 ENOG4106PMH Extracellular solute-binding protein family 3 CH60_395 ENOG4107GFK fumarate CH60_3951 ENOG4105E2Z phosphate ABC transporter (Permease CH60_3952 ENOG4105C8U phosphate abc transporter CH60_3953 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) CH60_3954 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) CH60_3962 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) CH60_3964 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation CH60_3967 ENOG4105QTB Flavodoxin CH60_3968 ENOG4108VVK transcriptional Regulator, AsnC CH60_397 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CH60_3974 ENOG4108RVA ribokinase CH60_3975 ENOG4105C0R drug resistance transporter emrb qaca subfamily CH60_3977 ENOG4107EJG GntR family transcriptional regulator CH60_3983 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b CH60_3985 ENOG4105PC1 Conserved Protein CH60_3986 ENOG4105E27 serine threonine protein kinase CH60_3987 ENOG4108Z33 Thiol disulfide Interchange Protein CH60_3988 ENOG4105C2M dna polymerase I CH60_399 ENOG4105D05 Receptor CH60_3991 ENOG4105D4P Coproporphyrinogen iii oxidase CH60_3992 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CH60_3993 ENOG4105CUX Signal transduction histidine kinase CH60_3994 ENOG4105C5F glutamine synthetase CH60_3996 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 CH60_3997 ENOG4107S2Z UPF0761 membrane protein CH60_4 ENOG4105D2N Aldolase CH60_40 ENOG4105BZU Histidine kinase CH60_4001 ENOG4105SUU thioesterase domain CH60_4002 ENOG4105JV1 AsmA family CH60_4003 ENOG4105C2W permease CH60_4004 ENOG4105D6U Sodium Glutamate Symporter CH60_4005 ENOG4105CB5 ATP-dependent DNA helicase recG CH60_4006 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase CH60_4007 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CH60_4010 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) CH60_4011 ENOG4105EN6 Membrane CH60_4012 ENOG4105DSJ YicC domain protein CH60_4017 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase CH60_4020 ENOG4105W0E 50S ribosomal protein L33 CH60_4024 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase CH60_4025 ENOG4105D16 lipopolysaccharide heptosyltransferase i CH60_4026 ENOG4105XA0 heptosyltransferase ii CH60_4028 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) CH60_403 ENOG4105CA0 peroxidase CH60_4030 ENOG4105PXI polysaccharide deacetylase CH60_4031 ENOG4105PXI polysaccharide deacetylase CH60_4032 ENOG41063SB peptidase CH60_4034 ENOG4107YZP Rhodanese domain protein CH60_4035 ENOG4105VW4 glutaredoxin 3 CH60_4038 ENOG4105D7W serine acetyltransferase CH60_4039 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) CH60_404 ENOG4105E89 ABC transporter CH60_4040 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CH60_4041 ENOG4105E0F Histidine kinase CH60_4042 ENOG4105E3W Two component transcriptional regulator (Winged helix family CH60_4043 ENOG4105FMW periplasmic CH60_4048 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein CH60_4050 ENOG4107QPK )-transporter CH60_4051 ENOG4105JSC dimethylmenaquinone methyltransferase CH60_4053 ENOG4107F9Y LysR family transcriptional regulator CH60_4055 ENOG4105EBK exported protein CH60_4056 ENOG4108VTS Membrane CH60_4057 ENOG4105DP0 ferredoxin-NADP reductase CH60_4058 ENOG4105CBT Fructose-1,6-bisphosphatase CH60_4059 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) CH60_4060 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CH60_4062 ENOG4108RS6 transposase CH60_4063 ENOG4108JJA ABC, transporter CH60_4064 ENOG4108MBX Secretion Protein CH60_4068 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CH60_4071 ENOG41063M6 Cell Division Protein CH60_4072 ENOG4105ETE Transcriptional regulator (LacI family CH60_4074 ENOG4105C25 Primosomal protein n' CH60_4076 ENOG4108Z12 YiaAB two helix domain-containing protein CH60_4078 ENOG4105C28 cystathionine CH60_4079 ENOG4105CFH Aspartokinase CH60_4080 ENOG4105SYT Methylenetetrahydrofolate reductase CH60_4081 ENOG4105DQ6 Transposase CH60_4083 ENOG4105MEV Acyl-transferase CH60_4084 ENOG4106EAR Fimbrial protein CH60_4087 ENOG4108TTM chaperone CH60_4089 ENOG4105CMG Carbohydrate kinase CH60_409 ENOG4105DKT Transcriptional regulator CH60_4091 ENOG4105DFW ABC transporter CH60_4093 ENOG4107RNG ABC transporter CH60_4094 ENOG4105T16 Transcriptional regulator (AraC family) CH60_4096 ENOG4105DFP Integrase CH60_4098 ENOG4105ZTC transcriptional activator, Ogr delta CH60_41 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) CH60_4103 ENOG4108IPW abc transporter atp-binding protein CH60_4105 ENOG4105CM4 permease protein CH60_411 ENOG4105CMT Dihydroxyacetone kinase CH60_4111 ENOG4105C6T cysteine synthase CH60_4113 ENOG4105C84 Histidine ammonia-lyase CH60_4114 ENOG4105C85 amino acid CH60_4118 ENOG4105D52 delta-aminolevulinic acid dehydratase CH60_4119 ENOG4105MDZ Transcriptional activator rfaH CH60_412 ENOG4105CHR reductase CH60_4121 ENOG4107QK7 reductase CH60_4125 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CH60_4126 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) CH60_4127 ENOG4108RR8 protoporphyrinogen oxidase CH60_413 ENOG4105CPQ Dehydrogenase CH60_4132 ENOG4105D4A Cell wall formation (By similarity) CH60_4133 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase CH60_4138 ENOG4105DQ6 Transposase CH60_414 ENOG4108YZG isomerase CH60_4141 ENOG4105C6V Glycerol-3-phosphate dehydrogenase CH60_4142 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CH60_4147 ENOG4108HRK Histidine kinase CH60_415 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) CH60_4153 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CH60_4154 ENOG41076UM multiple antibiotic resistance (MarC)-related protein CH60_4158 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CH60_4159 ENOG4105C6Z Gluconate CH60_416 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH60_4160 ENOG4105DIQ Transcriptional regulator CH60_4164 ENOG4108NYK Tape measure protein CH60_417 ENOG4108K5P (LipO)protein CH60_4183 ENOG4105FA0 parb-like partition protein CH60_4184 ENOG4105FA0 parb-like partition protein CH60_4185 ENOG4105CB5 ATP-dependent DNA helicase recG CH60_4194 ENOG4108RS6 transposase CH60_4196 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH60_4197 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CH60_42 ENOG4108JQ7 (ABC) transporter CH60_4203 ENOG4105D2X ABC transporter substrate-binding protein CH60_4205 ENOG4106JVB Replication Protein CH60_4213 ENOG4105C68 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity) CH60_4215 ENOG4105C2M dna polymerase I CH60_422 ENOG4105CE5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity) CH60_4221 ENOG4106J5W DNA polymerase III (alpha subunit) CH60_4225 ENOG4106J5W DNA polymerase III (alpha subunit) CH60_4232 ENOG4108D1K outer membrane usher protein CH60_4233 ENOG4108UIF Chaperone CH60_4234 ENOG4106PHM regulatory protein CH60_424 ENOG4105N0Z inner membrane protein ygbE CH60_4244 ENOG4105FEQ ParB domain protein nuclease CH60_4248 ENOG41073YN Protein of unknown function (DUF1380) CH60_425 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) CH60_4253 ENOG4106RMF ParB family CH60_4261 ENOG4105EQR Transposase IS116 IS110 IS902 CH60_4267 ENOG4105UZW Tail fiber assembly protein CH60_4269 ENOG4108X9F tail fiber protein CH60_4269 ENOG4108X9F tail fiber protein CH60_4298 ENOG4105CMM transposase CH60_43 ENOG4105C3U ABC transporter CH60_4300 ENOG4105CMM transposase CH60_4308 ENOG4106CQM replication CH60_4309 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) CH60_4318 ENOG4105D13 transposase CH60_4320 ENOG4108C33 Resolvase CH60_4324 ENOG4105CMM transposase CH60_4333 ENOG4105CMM transposase CH60_4339 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB CH60_4340 ENOG4105EZN Cobyrinic acid ac-diamide synthase CH60_436 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase CH60_4368 ENOG4105XUP Phage derived protein Gp49-like (DUF891) CH60_437 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) CH60_44 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH60_441 ENOG4105DXN mazG family CH60_442 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CH60_443 ENOG4105BZU Histidine kinase CH60_444 ENOG4105C0H protease CH60_446 ENOG4105DUF Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity) CH60_448 ENOG4105EN6 Membrane CH60_45 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CH60_452 ENOG4105S6R Iron-hydroxamate transporter permease subunit CH60_453 ENOG4105J76 Periplasmic binding protein CH60_454 ENOG4105E0A ABC, transporter CH60_455 ENOG4105BZ4 penicillin-binding protein CH60_456 ENOG4105CQ7 ATP-dependent helicase CH60_457 ENOG4107XID 2'-5' rna ligase CH60_459 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters CH60_46 ENOG4105DEF Extracellular solute-binding protein, family 5 CH60_460 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) CH60_461 ENOG4105DJ0 Poly(A) Polymerase CH60_462 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CH60_466 ENOG4107BJW polysaccharide deacetylase CH60_468 ENOG4105E3A (ABC) transporter CH60_469 ENOG4105DA5 (ABC) transporter CH60_470 ENOG41077A9 carbonic anhydrase CH60_471 ENOG4108UGV hypoxanthine phosphoribosyltransferase CH60_472 ENOG4105E3B Multicopper oxidase CH60_473 ENOG4108ZRK uncharacterized protein yacC CH60_476 ENOG4105RPH Inner membrane protein YddG CH60_478 ENOG4107QIJ Aconitate hydratase 2 CH60_479 ENOG4108RS6 transposase CH60_48 ENOG4105D5K Hemolysin activator protein CH60_480 ENOG4107QN2 dihydrolipoyl dehydrogenase CH60_481 ENOG4107QSN dihydrolipoamide acetyltransferase CH60_482 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) CH60_483 ENOG41073TP transcriptional regulator CH60_484 ENOG4105C85 amino acid CH60_485 ENOG4106A72 regulatory protein AmpE CH60_486 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CH60_487 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase CH60_488 ENOG4108ZUW Major pilin subunit CH60_489 ENOG4107QHF type ii secretion system protein e CH60_490 ENOG4105D7Q type ii secretion system CH60_492 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) CH60_495 ENOG4108RS6 transposase CH60_498 ENOG4108RS6 transposase CH60_500 ENOG4105FHY Opacity-associated protein A CH60_501 ENOG4108V1T peptidylprolyl cis-trans isomerase CH60_503 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic CH60_504 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase CH60_505 ENOG4108UUE Transcriptional regulator CH60_506 ENOG41061GZ Protein of unknown function (DUF1107) CH60_507 ENOG4105C37 (CBS) domain CH60_509 ENOG4105CFU surface antigen CH60_51 ENOG4105CXY transporter CH60_510 ENOG4105MA0 exported protein CH60_511 ENOG4108ZHD aig2 family CH60_512 ENOG4105F0N pyrophosphate phospho-hydrolase CH60_514 ENOG4105DFU Cell wall formation (By similarity) CH60_518 ENOG4105HVQ Regulatory factor of maltose metabolism CH60_52 ENOG4105BZU Histidine kinase CH60_520 ENOG4105EAH synthase CH60_523 ENOG4105QYV Membrane CH60_527 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase CH60_528 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) CH60_529 ENOG4105HBR Rna-binding protein CH60_53 ENOG4108KX4 response regulator CH60_531 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) CH60_532 ENOG4105EEI dihydropteroate synthase CH60_538 ENOG4105CHV Transcription elongation factor NusA CH60_54 ENOG4105DIJ Phosphoethanolamine transferase CH60_544 ENOG4105DQ6 Transposase CH60_547 ENOG4105C1J atp-dependent rna helicase CH60_550 ENOG4105DEN Luciferase family CH60_553 ENOG4105BZS acriflavin resistance protein CH60_554 ENOG4105ENJ RND efflux system, outer membrane lipoprotein CH60_555 ENOG4106RZ4 Peptidase U32 CH60_556 ENOG4105CFP Peptidase U32 CH60_557 ENOG4105XPQ lipid carrier protein CH60_558 ENOG4108YYD acetyltransferase CH60_56 ENOG4105C85 amino acid CH60_563 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component CH60_564 ENOG4105DRS transport system, permease CH60_569 ENOG4105K4T epimerase CH60_570 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein CH60_571 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) CH60_572 ENOG4105FD8 phosphonate metabolism protein PhnM CH60_573 ENOG4105HRV phosphonate c-p lyase system protein phnl CH60_574 ENOG4105ENV phosphonate C-P lyase system protein PhnK CH60_575 ENOG4105FT8 Phosphonate metabolism CH60_576 ENOG4105EKV Phosphonate metabolism protein CH60_577 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH CH60_578 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG CH60_579 ENOG4107RJJ Transcriptional regulator CH60_581 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) CH60_582 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase CH60_583 ENOG4108JQ7 (ABC) transporter CH60_584 ENOG4105C3U ABC transporter CH60_585 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CH60_586 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CH60_589 ENOG4105XEP YhcH YjgK YiaL family protein CH60_590 ENOG4105DBV ornithine carbamoyltransferase CH60_591 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) CH60_592 ENOG4108MJ3 acetyltransferase CH60_593 ENOG4105CA4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity) CH60_594 ENOG4105MYG DNA polymerase iii, chi subunit CH60_596 ENOG4108M8S permease YjgP YjgQ family protein CH60_597 ENOG4108K5H permease YjgP YjgQ family protein CH60_6 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CH60_60 ENOG4105E98 transcriptional regulator DeoR family CH60_601 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) CH60_604 ENOG4108RS6 transposase CH60_605 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA CH60_606 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane CH60_607 ENOG4105C34 Pseudouridine synthase CH60_608 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CH60_609 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CH60_616 ENOG4105T42 (LipO)protein CH60_617 ENOG4105JIM Phosphatidylserine synthase CH60_618 ENOG4105CD5 CoA-binding domain protein CH60_619 ENOG4106IUH DTW domain containing protein CH60_620 ENOG4105K63 Thioredoxin CH60_621 ENOG4105EIB trna rrna methyltransferase CH60_622 ENOG4105C0R drug resistance transporter emrb qaca subfamily CH60_623 ENOG4105CW7 secretion protein, HlyD family CH60_624 ENOG4105NTK Transcriptional repressor Mpra CH60_625 ENOG4105ZED uncharacterized protein ygaH CH60_626 ENOG4108UMN azlc family CH60_627 ENOG4105EQ0 Major Facilitator superfamily CH60_634 ENOG4105E5Q amino acid AbC transporter CH60_636 ENOG4105C5R Aminotransferase CH60_64 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CH60_643 ENOG4108IJ9 (ABC) transporter CH60_644 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component CH60_647 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) CH60_648 ENOG4105FDP GntR family transcriptional regulator CH60_667 ENOG4108WC9 type VI secretion system effector, hcp1 family CH60_67 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) CH60_679 ENOG4105WH1 Two component transcriptional regulator luxr family CH60_680 ENOG4105XVG cytoplasmic protein CH60_681 ENOG4105RA2 Membrane CH60_683 ENOG4108T1M outer membrane protein x CH60_685 ENOG4105C85 amino acid CH60_688 ENOG4105DBE peroxidase CH60_69 ENOG4105MJ2 Competence protein CH60_691 ENOG4105CK7 Sodium proline symporter CH60_693 ENOG4105C26 Dehydrogenase CH60_696 ENOG4105CDA abc transporter atp-binding protein CH60_697 ENOG4105E5Q amino acid AbC transporter CH60_698 ENOG4105EAB amino acid AbC transporter CH60_699 ENOG4105K6H D-cysteine desulfhydrase CH60_7 ENOG4105CNN ABC, transporter CH60_700 ENOG4108M9K flagella biosynthesis protein FliZ CH60_701 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CH60_702 ENOG4105I03 Flagellin CH60_703 ENOG4105DTS flagellar hook-associated CH60_704 ENOG4105MQ3 flagellar protein FliS CH60_707 ENOG4108T5G Adenylate CH60_708 ENOG4105DHT Metal Dependent Phosphohydrolase CH60_71 ENOG4105RID UPF0379 protein yhcN CH60_712 ENOG4105VQ0 flagellar hook-basal body complex protein fliE CH60_713 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CH60_714 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CH60_715 ENOG41090PJ Flagellar assembly protein CH60_716 ENOG4108JIR Flagellum-specific ATP synthase CH60_717 ENOG4105GSA Flagellar export protein flij CH60_718 ENOG4105WF4 Flagellar hook-length control protein CH60_719 ENOG4107ZI8 flagellar basal body-associated protein flil CH60_720 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CH60_721 ENOG4105DD5 Flagellar motor switch protein CH60_723 ENOG4105CN7 Flagellar biosynthetic protein FliP CH60_724 ENOG4105VS8 Flagellar biosynthetic protein fliq CH60_725 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CH60_728 ENOG4108MGF sugar kinase CH60_729 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane CH60_73 ENOG4105CE1 Ferrous iron transport protein b CH60_730 ENOG4105C2J ABC transporter CH60_732 ENOG4105CNN ABC, transporter CH60_734 ENOG4105DKT Transcriptional regulator CH60_735 ENOG4105DTJ flagellar hook-associated protein CH60_736 ENOG4105E1Q flagellar hook-associated protein CH60_737 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj CH60_74 ENOG4105XFK Ferrous iron transport protein A CH60_740 ENOG4105CGA flagellar basal-body rod protein FlgG CH60_741 ENOG4108KPB Flagellar basal-body rod protein FlgF CH60_742 ENOG4105BZE flagellar hook protein, FlgE CH60_743 ENOG4105W00 Flagellar hook capping protein CH60_744 ENOG4108ZC9 flagellar basal-body rod protein flgc CH60_745 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CH60_746 ENOG4105CKS Flagella basal body P-ring formation protein flgA CH60_747 ENOG4105M9M anti-sigma28 factor FlgM CH60_748 ENOG4105QVD Flagella synthesis protein FlgN CH60_75 ENOG4105BZM domain protein CH60_750 ENOG4108RS6 transposase CH60_752 ENOG4105W13 flagellar protein CH60_753 ENOG4105D7B Flagellar biosynthesis protein flha CH60_754 ENOG4105D00 flagellar biosynthetic protein flhB CH60_757 ENOG4105NKT exported protein CH60_759 ENOG4105FXM Copper resistance protein CH60_76 ENOG4108RRZ Transcription elongation factor GreB CH60_760 ENOG41090A1 ferritin CH60_761 ENOG4105MPK DNA polymerase III subunit theta CH60_763 ENOG4105CUG Oligopeptidase b CH60_766 ENOG4105X2V dna damage-inducible protein CH60_767 ENOG4105C1J atp-dependent rna helicase CH60_77 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CH60_770 ENOG4105CRQ synthase (Component I) CH60_772 ENOG4105EJQ L-serine dehydratase CH60_773 ENOG4107UWN reductase CH60_774 ENOG4105EFA 4-hydroxyphenylacetate CH60_78 ENOG4105E0F Histidine kinase CH60_780 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase CH60_781 ENOG4105C26 Dehydrogenase CH60_784 ENOG4108V8F Transcriptional regulator, MarR family CH60_785 ENOG4105EE5 Membrane protein terC CH60_786 ENOG4108EQA pts system CH60_787 ENOG4105ETZ PTS System CH60_788 ENOG4105F3R pts system mannose fructose sorbose family iid CH60_796 ENOG41077RS Phosphatase CH60_797 ENOG4105E8V Alpha Beta Hydrolase Fold protein CH60_799 ENOG4108HPI phosphatidate Cytidylyltransferase CH60_800 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase CH60_807 ENOG4105WQ3 Rna-binding protein CH60_808 ENOG4108RS6 transposase CH60_81 ENOG4105VEJ Heat shock protein CH60_811 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CH60_813 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) CH60_814 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit CH60_815 ENOG4105CV6 ABC transporter, permease CH60_816 ENOG4108I0Y (ABC) transporter CH60_817 ENOG4108UJV acyl-CoA thioesterase i CH60_818 ENOG4105E1F short-chain dehydrogenase reductase CH60_819 ENOG4107QR8 Thioredoxin CH60_82 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 CH60_820 ENOG4107QX8 SPFH domain, Band 7 family protein CH60_821 ENOG4105G5H Membrane CH60_822 ENOG4108Z6Z Transcriptional regulator CH60_823 ENOG4105C59 p-type ATPase CH60_824 ENOG4105MBR gumn family CH60_825 ENOG4108Z66 YbaK ebsC protein CH60_828 ENOG4105CGH 5'-nucleotidase CH60_829 ENOG4105CGH 5'-nucleotidase CH60_83 ENOG4105DQY intracellular growth attenuator CH60_830 ENOG4105CGH 5'-nucleotidase CH60_831 ENOG4105EU0 Major facilitator Superfamily CH60_832 ENOG4105CKD glutathione-regulated potassium-efflux system protein CH60_833 ENOG4107RE1 Inosine-guanosine kinase CH60_834 ENOG4108QY5 Ferric enterobactin transport protein CH60_837 ENOG4105CJT Mannose-1-phosphate guanylyltransferase CH60_838 ENOG4105C30 Nad-dependent epimerase dehydratase CH60_839 ENOG4105C0K Gdp-mannose 4,6-dehydratase CH60_840 ENOG4105C0K Gdp-mannose 4,6-dehydratase CH60_841 ENOG4108TJN glycosyl transferase group 1 CH60_85 ENOG4107RK2 ADP-ribose diphosphatase NudE CH60_850 ENOG4108SMP Nad-dependent epimerase dehydratase CH60_851 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CH60_852 ENOG4105FAW cDP-glucose 4,6-dehydratase CH60_853 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase CH60_854 ENOG4108EX3 reductase CH60_86 ENOG4108JQC penicillin-binding protein 1A CH60_860 ENOG4107QMP dna polymerase iii subunits gamma and tau CH60_862 ENOG4105WD1 Membrane CH60_864 ENOG4105EGS Mechanosensitive ion channel CH60_865 ENOG41090EX DsrE family CH60_866 ENOG4108IG5 Transcriptional regulator CH60_867 ENOG4105C1P efflux transporter, rnd family, mfp subunit CH60_868 ENOG4105BZS acriflavin resistance protein CH60_870 ENOG4105YK5 50S ribosomal protein L36 CH60_872 ENOG4108UKR Biofilm formation regulator YbaJ CH60_873 ENOG4105KF5 hemolysin expression-modulating protein CH60_874 ENOG41080UX Methyltransferase CH60_875 ENOG4108MNP Glycoprotein polysaccharide metabolism CH60_876 ENOG4105C29 acyl-CoA thioesterase CH60_877 ENOG4105BZU Histidine kinase CH60_878 ENOG4108YZA Nitrogen regulatory protein pii CH60_879 ENOG4105BZ1 (ABC) transporter CH60_880 ENOG4105BZ1 (ABC) transporter CH60_881 ENOG4108XM1 transcriptional regulator AsnC family CH60_882 ENOG4105C6T cysteine synthase CH60_884 ENOG4108NFA extracellular solute-binding protein CH60_886 ENOG4108TGP Thioesterase superfamily protein CH60_887 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein CH60_888 ENOG4105EIN peptidylprolyl cis-trans isomerase CH60_889 ENOG4105K70 DNA-binding protein CH60_890 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) CH60_895 ENOG4105M85 Bola protein CH60_896 ENOG4105IEY (LipO)protein CH60_897 ENOG4105EYM Major Facilitator superfamily CH60_898 ENOG4108NFH Sugar hydrolase CH60_899 ENOG4105E2S oxidase) subunit II CH60_900 ENOG4105BZ9 Cytochrome C oxidase, subunit I CH60_901 ENOG4105CCU oxidase (Subunit III) CH60_902 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) CH60_904 ENOG4107RDB Major Facilitator CH60_906 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CH60_907 ENOG4107S0N DJ-1 family CH60_91 ENOG4105E4G Type IV pilus CH60_910 ENOG4105CTB Polyprenyl synthetase CH60_912 ENOG4108RS6 transposase CH60_913 ENOG4108ZAI phosphatidylglycerophosphatase a CH60_914 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) CH60_917 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) CH60_921 ENOG4108RS6 transposase CH60_922 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CH60_923 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CH60_924 ENOG4105VIE preprotein translocase, subunit YajC CH60_926 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) CH60_927 ENOG4108ZYK Acyl carrier protein phosphodiesterase CH60_928 ENOG4105D3R alkyl hydroperoxide reductase CH60_931 ENOG4105CHR reductase CH60_932 ENOG4107R28 alpha amylase, catalytic region CH60_933 ENOG4105C85 amino acid CH60_934 ENOG4105CWM branched-chain amino acid transport system II carrier protein CH60_936 ENOG4105BZU Histidine kinase CH60_937 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CH60_938 ENOG4107RH8 nuclease SbcCD subunit D CH60_939 ENOG4105EYH Exonuclease CH60_940 ENOG4105DKQ ROK family CH60_945 ENOG4105F2W methyltransferase CH60_956 ENOG4105CIN aminoacyl-histidine dipeptidase CH60_96 ENOG4105DJV ribulose-phosphate 3-epimerase CH60_960 ENOG4105CJ2 (LipO)protein CH60_964 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH60_965 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH60_966 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CH60_967 ENOG4105E7A Glutamine amidotransferase CH60_968 ENOG4105F7V ErfK ybiS ycfS ynhG family protein CH60_97 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) CH60_970 ENOG4107QPN acyl-Coa dehydrogenase CH60_972 ENOG4106YJS accessory processing protein CH60_976 ENOG4105C5R Aminotransferase CH60_979 ENOG4105DFP Integrase CH60_98 ENOG4105C31 Tryptophanyl-tRNA synthetase CH60_982 ENOG4105EV9 Alpha Beta Hydrolase CH60_984 ENOG4105NNH LexA regulated protein CH60_985 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) CH60_986 ENOG41090R7 Ferric uptake CH60_991 ENOG4105CI1 PTS System CH60_993 ENOG4105CE4 GlcNAc 6-P deacetylase CH60_994 ENOG4105E2R ROK family CH60_995 ENOG4105D4U had-superfamily hydrolase, subfamily iia CH60_996 ENOG4105CAQ asparagine synthetase