locus_tag old_locus_tag gene Name start end strand product note type ID NCBI 37382 37463 + tRNA-OTHER tRNA-pseudo-TAA pseudogenic_tRNA gene-MW570730.1:37382..37463 http://www.ncbi.nlm.nih.gov/gene/?term= 37299 37372 + tRNA-Met tRNA rna-MW570730.1:37299..37372 http://www.ncbi.nlm.nih.gov/gene/?term= 37118 37191 + tRNA-Arg tRNA rna-MW570730.1:37118..37191 http://www.ncbi.nlm.nih.gov/gene/?term= YerA41_001 YerA41_001 YerA41_001 291 650 + hypothetical protein gene gene-YerA41_001 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_001 YerA41_002 YerA41_002 YerA41_002 647 889 + hypothetical protein gene gene-YerA41_002 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_002 YerA41_003 YerA41_003 YerA41_003 879 1184 + structural protein gene gene-YerA41_003 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_003 YerA41_004 YerA41_004 YerA41_004 1280 1672 + hypothetical protein gene gene-YerA41_004 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_004 YerA41_005 YerA41_005 YerA41_005 1684 2358 + structural protein gene gene-YerA41_005 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_005 YerA41_006 YerA41_006 YerA41_006 2355 2870 + putative uridine monophosphate kinase some similarity to Uridine-monophosphate kinase as per HHpred search on NCBI conserved domain database v_3.17%3B putative uridine monophosphate kinase%2C UMPK%3B putative uridine monophosphate kinase gene gene-YerA41_006 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_006 YerA41_007 YerA41_007 YerA41_007 2892 3212 + hypothetical protein gene gene-YerA41_007 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_007 YerA41_008 YerA41_008 YerA41_008 3228 3656 + hypothetical protein gene gene-YerA41_008 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_008 YerA41_009 YerA41_009 YerA41_009 3656 3898 + hypothetical protein some similarity to a C-terminal LabA_like_C domain%3Bas per HHpred search on NCBI conserved domain databasev_3.17 gene gene-YerA41_009 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_009 YerA41_010 YerA41_010 YerA41_010 3973 4440 + hypothetical protein gene gene-YerA41_010 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_010 YerA41_011 YerA41_011 YerA41_011 4440 5012 + hypothetical protein gene gene-YerA41_011 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_011 YerA41_012 YerA41_012 YerA41_012 4996 5760 + hypothetical protein gene gene-YerA41_012 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_012 YerA41_013 YerA41_013 YerA41_013 5782 7404 + DNA helicase Strong similarity to DinG family helicase Csf4 cd09708 as per HHpred search on NCBI conserved domain database v_3.17 gene gene-YerA41_013 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_013 YerA41_014 YerA41_014 YerA41_014 7489 7689 + hypothetical protein gene gene-YerA41_014 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_014 YerA41_015 YerA41_015 YerA41_015 7700 7879 + hypothetical protein gene gene-YerA41_015 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_015 YerA41_016 YerA41_016 YerA41_016 7919 8044 + hypothetical protein gene gene-YerA41_016 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_016 YerA41_017 YerA41_017 YerA41_017 8041 8244 + hypothetical protein gene gene-YerA41_017 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_017 YerA41_018 YerA41_018 YerA41_018 8244 8876 + DNA/RNA non-specific endonuclease phage particle associated protein%3B cd00091%3B strong similarity to conserved domain of DNA/RNA non-specific endonuclease%3B as per HHpred search on NCBI conserved domain database v_3.17 gene gene-YerA41_018 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_018 YerA41_019 YerA41_019 YerA41_019 8851 8946 + structural protein gene gene-YerA41_019 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_019 YerA41_020 YerA41_020 YerA41_020 8953 9237 + homing endonuclease gene gene-YerA41_020 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_020 YerA41_021 YerA41_021 YerA41_021 9234 9659 + C39 family peptidase gene gene-YerA41_021 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_021 YerA41_022 YerA41_022 YerA41_022 9667 10044 + hypothetical protein gene gene-YerA41_022 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_022 YerA41_023 YerA41_023 YerA41_023 10047 10355 + hypothetical protein gene gene-YerA41_023 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_023 YerA41_024 YerA41_024 YerA41_024 10348 10623 + hypothetical protein gene gene-YerA41_024 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_024 YerA41_025 YerA41_025 YerA41_025 10640 10744 + hypothetical protein gene gene-YerA41_025 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_025 YerA41_026 YerA41_026 YerA41_026 10755 11117 + hypothetical protein weak similarity to Glutamine amidotransferase gene gene-YerA41_026 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_026 YerA41_027 YerA41_027 YerA41_027 11130 11288 + hypothetical protein gene gene-YerA41_027 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_027 YerA41_028 YerA41_028 YerA41_028 11285 11407 + hypothetical protein gene gene-YerA41_028 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_028 YerA41_029 YerA41_029 YerA41_029 11395 11643 + hypothetical protein gene gene-YerA41_029 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_029 YerA41_030 YerA41_030 YerA41_030 11662 11835 + hypothetical protein significant similarity to conserved domains of LysWand Rubredoxin gene gene-YerA41_030 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_030 YerA41_031 YerA41_031 YerA41_031 11825 12172 + hypothetical protein gene gene-YerA41_031 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_031 YerA41_032 YerA41_032 YerA41_032 12169 12390 + hypothetical protein gene gene-YerA41_032 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_032 YerA41_033 YerA41_033 YerA41_033 12618 13112 + hypothetical protein gene gene-YerA41_033 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_033 YerA41_034 YerA41_034 YerA41_034 13287 13406 + hypothetical protein weak similarity to conserved domain INT_RitA_C_like gene gene-YerA41_034 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_034 YerA41_035 YerA41_035 YerA41_035 13413 13685 + hypothetical protein gene gene-YerA41_035 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_035 YerA41_036 YerA41_036 YerA41_036 13730 14347 + hypothetical protein Significantly similar to conserved domain NADAR%3B Escherichia coli swarming motility protein YbiA gene gene-YerA41_036 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_036 YerA41_037 YerA41_037 YerA41_037 14340 14714 + hypothetical protein gene gene-YerA41_037 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_037 YerA41_038 YerA41_038 YerA41_038 14714 15247 + hypothetical protein gene gene-YerA41_038 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_038 YerA41_039 YerA41_039 YerA41_039 15244 15426 + hypothetical protein gene gene-YerA41_039 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_039 YerA41_040 YerA41_040 YerA41_040 15429 16343 + hypothetical protein gene gene-YerA41_040 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_040 YerA41_041 YerA41_041 YerA41_041 16402 16752 + hypothetical protein gene gene-YerA41_041 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_041 YerA41_042 YerA41_042 YerA41_042 16791 17096 + hypothetical protein gene gene-YerA41_042 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_042 YerA41_043 YerA41_043 YerA41_043 17231 17440 + pseudouridine synthase-like protein gene gene-YerA41_043 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_043 YerA41_044 YerA41_044 YerA41_044 17451 17825 + hypothetical protein gene gene-YerA41_044 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_044 YerA41_045 YerA41_045 YerA41_045 17825 18229 + hypothetical protein gene gene-YerA41_045 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_045 YerA41_046 YerA41_046 YerA41_046 18239 18667 + hypothetical protein gene gene-YerA41_046 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_046 YerA41_047 YerA41_047 YerA41_047 18667 19128 + hypothetical protein gene gene-YerA41_047 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_047 YerA41_048 YerA41_048 YerA41_048 19129 19338 + hypothetical protein gene gene-YerA41_048 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_048 YerA41_049 YerA41_049 YerA41_049 19400 19648 + hypothetical protein gene gene-YerA41_049 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_049 YerA41_050 YerA41_050 YerA41_050 19700 20071 + hypothetical protein gene gene-YerA41_050 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_050 YerA41_051 YerA41_051 YerA41_051 20080 20853 + 3'-5' exonuclease gene gene-YerA41_051 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_051 YerA41_052 YerA41_052 YerA41_052 20856 21044 + hypothetical protein Similarity to conserved domain of ribulose bisphosphate carboxylase/oxygenase gene gene-YerA41_052 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_052 YerA41_053 YerA41_053 YerA41_053 21044 21658 + hypothetical protein Similarity to conserved domain of Zn-ribbon_RPC11%3B C-terminal zinc ribbon domain of RPC11 subunit of RNA polymerase III gene gene-YerA41_053 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_053 YerA41_054 YerA41_054 YerA41_054 21670 22209 + hypothetical protein some similarity to conserved domain of 4-hydroxy-3-methylbut-2-enyl diphosphate reductase or GT5 type glycosyltransferase%3B as per HHpred search on NCBI conserved domain database v_3.17 gene gene-YerA41_054 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_054 YerA41_055 YerA41_055 YerA41_055 22202 22849 + hypothetical protein gene gene-YerA41_055 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_055 YerA41_056 YerA41_056 YerA41_056 22853 23167 + hypothetical protein gene gene-YerA41_056 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_056 YerA41_057 YerA41_057 YerA41_057 23231 23506 + hypothetical protein gene gene-YerA41_057 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_057 YerA41_058 YerA41_058 YerA41_058 23508 23882 + hypothetical protein gene gene-YerA41_058 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_058 YerA41_059 YerA41_059 YerA41_059 23860 24207 + structural protein gene gene-YerA41_059 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_059 YerA41_060 YerA41_060 YerA41_060 24197 24475 + hypothetical protein gene gene-YerA41_060 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_060 YerA41_061 YerA41_061 YerA41_061 24562 24993 + hypothetical protein gene gene-YerA41_061 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_061 YerA41_062 YerA41_062 YerA41_062 24977 25240 + hypothetical protein gene gene-YerA41_062 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_062 YerA41_063 YerA41_063 YerA41_063 25249 26340 + ribonucleotide reductase of class Ia (aerobic)%2C beta subunit gene gene-YerA41_063 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_063 YerA41_064 YerA41_064 YerA41_064 26340 28613 + ribonucleotide reductase of class Ia (aerobic)%2C alpha subunit present in phage particle%2C structural protein? gene gene-YerA41_064 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_064 YerA41_065 YerA41_065 YerA41_065 28668 29201 + structural protein gene gene-YerA41_065 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_065 YerA41_066 YerA41_066 YerA41_066 29211 30632 + structural protein Significant similarity to conserved domain eu-GS%3B Eukaryotic Glutathione Synthetase (eu-GS) gene gene-YerA41_066 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_066 YerA41_067 YerA41_067 YerA41_067 30683 30925 + hypothetical protein gene gene-YerA41_067 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_067 YerA41_068 YerA41_068 YerA41_068 30925 31572 + trimeric dUTP diphosphatase gene gene-YerA41_068 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_068 YerA41_069 YerA41_069 YerA41_069 31585 31959 + hypothetical protein gene gene-YerA41_069 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_069 YerA41_070 YerA41_070 YerA41_070 32046 32420 + mono-ADP-ribosylating toxin gene gene-YerA41_070 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_070 YerA41_071 YerA41_071 YerA41_071 32483 33133 + hypothetical protein Similarity to conserved domain PBP1_ABC_sugar_binding_like%3B Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily. gene gene-YerA41_071 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_071 YerA41_072 YerA41_072 YerA41_072 33146 33466 + hypothetical protein gene gene-YerA41_072 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_072 YerA41_073 YerA41_073 YerA41_073 33468 34289 + hypothetical protein gene gene-YerA41_073 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_073 YerA41_074 YerA41_074 YerA41_074 34270 34650 + hypothetical protein Some similarity to conserved domain LysW%3B Lysine biosynthesis protein LysW gene gene-YerA41_074 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_074 YerA41_075 YerA41_075 YerA41_075 34760 34936 + hypothetical protein gene gene-YerA41_075 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_075 YerA41_076 YerA41_076 YerA41_076 35049 35624 + hypothetical protein gene gene-YerA41_076 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_076 YerA41_077 YerA41_077 YerA41_077 35627 35815 + hypothetical protein Some similarity to conserved domain SafA-like%3B Saf-pilin pilus formation protein SafA gene gene-YerA41_077 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_077 YerA41_078 YerA41_078 YerA41_078 36018 36629 + hypothetical protein gene gene-YerA41_078 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_078 YerA41_079 YerA41_079 YerA41_079 36753 37061 + structural protein gene gene-YerA41_079 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_079 YerA41_080 YerA41_080 YerA41_080 37484 38248 + endonuclease Similarity to conserved domain Endonuclease_DUF559 gene gene-YerA41_080 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_080 YerA41_081 YerA41_081 YerA41_081 38235 39398 + hypothetical protein gene gene-YerA41_081 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_081 YerA41_082 YerA41_082 YerA41_082 39405 39713 + hypothetical protein Some similarities to conserved domains FERM_F1_SNX31%3B FERM (Four.1 protein%2C Ezrin%2C Radixin%2C Moesin) domain%2C F1 sub-domain%2C found in sorting nexin protein 31 (SNX31)%2C and DNA_pol_gammaA%3B Pol gammaA is a family A polymerase that is responsible for DNA replication and repair in mitochondria gene gene-YerA41_082 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_082 YerA41_083 YerA41_083 YerA41_083 39767 40234 + structural protein gene gene-YerA41_083 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_083 YerA41_084 YerA41_084 YerA41_084 40557 41054 + structural protein gene gene-YerA41_084 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_084 YerA41_085 YerA41_085 YerA41_085 41078 41542 + hypothetical protein gene gene-YerA41_085 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_085 YerA41_086 YerA41_086 YerA41_086 41695 42231 + mannosyltransferase cd03816%3B GT33_ALG1-like%3B chitobiosyldiphosphodolichol beta-mannosyltransferase and similar proteins. This family is most closely related to the GT33 family of glycosyltransferases.%3B structural protein%2C mannosyltransferase gene gene-YerA41_086 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_086 YerA41_087 YerA41_087 YerA41_087 42259 42729 + structural protein cd17510%3B T3SC_YbjN-like_2%3B Uncharacterized protein is structurally similar to type III secretion system chaperones and YbjN family proteins gene gene-YerA41_087 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_087 YerA41_088 YerA41_088 YerA41_088 42809 43369 + lytic murein transglycosylase Significant similarity to conserved domain cd13403%3BMLTF_like%3B Membrane-bound lytic murein transglycosylase F (MLTF) and similar proteins. This subfamily includes membrane-bound lytic murein transglycosylase F (MltF%2C murein lyase F) that degrades murein glycan strands.%3B structural protein%2C lytic murein transglycosylase gene gene-YerA41_088 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_088 YerA41_089 YerA41_089 YerA41_089 43378 43671 + hypothetical protein some similarity to conserved domain cd16364%3BT3SC_I_like%3B class I type III secretion system (T3SS) chaperones and similar proteins. This family contains class I type III secretion system (T3SS) chaperones mainly found in Gram-negative bacteria such as Pseudomonas%2C Yersinia%2C Salmonella%2C Escherichia and Erwinia%2C among others gene gene-YerA41_089 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_089 YerA41_090 YerA41_090 YerA41_090 43764 44084 + hypothetical protein some similarity to conserved domain cd04769%3B HTH_MerR2%3B Helix-Turn-Helix DNA binding domain of MerR2-like transcription regulators. Helix-turn-helix (HTH) transcription regulator MerR2 and related proteins. gene gene-YerA41_090 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_090 YerA41_091 YerA41_091 YerA41_091 44136 44636 + hypothetical protein gene gene-YerA41_091 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_091 YerA41_092 YerA41_092 YerA41_092 44685 44882 + hypothetical protein gene gene-YerA41_092 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_092 YerA41_093 YerA41_093 YerA41_093 44897 45127 + hypothetical protein some similarity to cd05568%3B PTS_IIB_bgl_like%3B PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved in sugar utilization gene gene-YerA41_093 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_093 YerA41_094 YerA41_094 YerA41_094 45114 45302 + hypothetical protein gene gene-YerA41_094 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_094 YerA41_095 YerA41_095 YerA41_095 45283 45666 + hypothetical protein gene gene-YerA41_095 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_095 YerA41_096 YerA41_096 YerA41_096 45681 46406 + structural protein Some similarity to cd11545%3B NTP-PPase_YP_001813558%3BNucleoside Triphosphate Pyrophosphohydrolase MazG-like domain found in Exiguobacterium sibiricum YP_001813558 gene gene-YerA41_096 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_096 YerA41_097 YerA41_097 YerA41_097 46419 46643 + hypothetical protein gene gene-YerA41_097 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_097 YerA41_098 YerA41_098 YerA41_098 46713 47294 + (pyro)phosphatase or 5'(3')-deoxyribonucleotidase Conserved domains cd02616%3B HAD_PPase%3B pyrophosphatase similar to Bacillus subtilis PpaX. This family includes Bacillus subtilis PpaX which hydrolyzes pyrophosphate formed during serine-46-phosphorylated HPr (P-Ser-HPr) dephosphorylation by the bifunctional enzyme HPr kinase/phosphorylase%2C and cd02587%3B HAD_5-3dNT%3B 5'(3')-deoxyribonucleotidase. This family includes cytosolic 5'(3')-deoxyribonucleotidase (cdN) and mitochondrial 5'(3')-deoxyribonucleotidase (mdN) gene gene-YerA41_098 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_098 YerA41_099 YerA41_099 YerA41_099 47297 49330 + topoisomerase cd03366%3B TOPRIM_TopoIIA_GyrB%3B TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit%3B structural protein%2C topoisomerase gene gene-YerA41_099 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_099 YerA41_100 YerA41_100 YerA41_100 49330 50652 + topoisomerase cd00187%3B TOP4c%3B DNA Topoisomerase%2C subtype IIA%3B domain A'%3B bacterial DNA topoisomerase IV (C subunit%2C ParC)%2C bacterial DNA gyrases (A subunit%2C GyrA)%2Cmammalian DNA toposiomerases II.%3B structural protein%2C topoisomerase gene gene-YerA41_100 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_100 YerA41_101 YerA41_101 YerA41_101 50704 51429 + 3'-5' exonuclease cd06131%3B DNA_pol_III_epsilon_Ecoli_like%3B DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins%3B structural protein%2C 3'-5' exonuclease gene gene-YerA41_101 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_101 YerA41_102 YerA41_102 YerA41_102 51469 51723 + hypothetical protein gene gene-YerA41_102 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_102 YerA41_103 YerA41_103 YerA41_103 51723 51932 + structural protein gene gene-YerA41_103 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_103 YerA41_104 YerA41_104 YerA41_104 51948 52865 + DnaK-like chaperone cd10227%3B ParM_like%3B Plasmid segregation protein ParM and similar proteins. ParM is a plasmid-encoded bacterial homolog of actin%2C which polymerizes into filaments similar to F-actin%2C and plays a vital role in plasmid segregation. cd10225%3B MreB_like%3B MreB and similar proteins. MreB is a bacterial protein which assembles into filaments resembling those of eukaryotic F-actin. cd10234%3B HSPA9-Ssq1-like_NBD%3B Nucleotide-binding domain of human HSPA9 and similar proteins. This subfamily includes human mitochondrial HSPA9 (also known as 70-kDa heat shock protein 9%2C CSA. cd11733%3B HSPA9-like_NBD%3B Nucleotide-binding domain of human HSPA9%2C Escherichia coli DnaK%2C and similar proteins gene gene-YerA41_104 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_104 YerA41_105 YerA41_105 YerA41_105 52875 53672 + dUTPase cd11527%3B NTP-PPase_dUTPase%3B Nucleoside TriphosphatePyrophosphohydrolase MazG-like domain foundin dimeric 2-Deoxyuridine 5'-triphosphatenucleotidohydrolase and similar proteins.%3B structural protein%2C dUTPase gene gene-YerA41_105 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_105 YerA41_106 YerA41_106 YerA41_106 53681 53968 + hypothetical protein gene gene-YerA41_106 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_106 YerA41_107 YerA41_107 YerA41_107 54013 55467 + helicase cd09639%3B Cas3_I%3B CRISPR/Cas system-associated protein Cas3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. cd09710%3B Cas3_I-D%3B CRISPR/Cas system-associated protein Cas3%3B Distinct diverged subfamily of Cas3 helicase domain%3B structural protein%2C helicase gene gene-YerA41_107 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_107 YerA41_108 YerA41_108 YerA41_108 55474 55638 + hypothetical protein gene gene-YerA41_108 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_108 YerA41_109 YerA41_109 YerA41_109 55704 56783 + hexameric helicase cd01122%3B GP4d_helicase%3B GP4d_helicase is a homohexameric 5'-3' helicases. Helicases couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands. cd00984%3B DnaB_C%3B DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the chromosome replication fork gene gene-YerA41_109 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_109 YerA41_110 YerA41_110 YerA41_110 56811 57032 + hypothetical protein gene gene-YerA41_110 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_110 YerA41_111 YerA41_111 YerA41_111 56992 57669 + hypothetical protein gene gene-YerA41_111 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_111 YerA41_112 YerA41_112 YerA41_112 57691 58824 + structural protein gene gene-YerA41_112 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_112 YerA41_113 YerA41_113 YerA41_113 58885 59853 + 5'-3' exonuclease cd09860%3B PIN_T4-like%3B FEN-like PIN domains of bacteriophage T3%2C T4 RNase H%2C T5-5'nuclease%2C and homologs. cd00008%3B PIN_53EXO-like%3B FEN-like PIN domains of the 5'-3' exonucleases of DNA polymerase I%2C bacteriophage T4 RNase H and T5-5' nucleases%2C and homologs gene gene-YerA41_113 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_113 YerA41_114 YerA41_114 YerA41_114 59936 60547 + hypothetical protein Some similarity to cd13946%3B LysW%3B Lysine biosynthesis protein LysW. LysW functions as a carrier protein in the biosynthesis pathway of lysine. cd10511%3B Zn-ribbon_TFS%3B C-terminal zinc ribbon domain of archaeal Transcription Factor S (TFS). TFS is an archaeal protein that stimulates the intrinsic cleavage activity of archaeal RNA polymerase gene gene-YerA41_114 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_114 YerA41_115 YerA41_115 YerA41_115 60531 60815 + hypothetical protein gene gene-YerA41_115 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_115 YerA41_116 YerA41_116 YerA41_116 60790 61641 + Cas4 like protein cd09659%3B Cas4_I-A%3B CRISPR/Cas system-associated protein Cas4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA gene gene-YerA41_116 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_116 YerA41_117 YerA41_117 YerA41_117 61653 64136 + nuclease with metallophosphatase domain cd00840%3B MPP_Mre11_N%3B Mre11 nuclease%2C N-terminal metallophosphatase domain. Mre11 (also known as SbcD in Escherichia coli) is a subunit of the MRX protein complex. cd00841%3B MPP_YfcE%3B Escherichia coli YfcE and related proteins%2C metallophosphatase domain. YfcE is a manganase-dependent metallophosphatase%2C found in bacteria and archaea%2C that cleaves bis-p-nitrophenyl phosphate%2C thymidine 5'-monophosphate-p-nitrophenyl ester%2C and p-nitrophenyl phosphorylcholine%2C but is unable to hydrolyze 2'%2C3 ' or 3'%2C5' cyclic nucleic phosphodiesters%2C and various phosphomonoesters%2C including p-nitrophenyl phosphate gene gene-YerA41_117 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_117 YerA41_118 YerA41_118 YerA41_118 64133 64690 + DNA repair ATPase cd03241%3B ABC_RecN%3B ATP-binding cassette domain of RecN. RecN ATPase involved in DNA repair%3B similar to ABC (ATP-binding cassette) transporter nucleotide-binding domain. cd03240%3B ABC_Rad50%3B ATP-binding cassette domain of Rad50. The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters%2C but are not associated with membrane-spanning domains%3B structural protein%2C DNA repair ATPase gene gene-YerA41_118 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_118 YerA41_119 YerA41_119 YerA41_119 64700 64864 + structural protein Some similarity to cd11745%3B Yos9_DD%3B C-terminal dimerization domain (DD) of Saccharomyces cerevisiae Yos9 and related proteins. cd00236%3B FinO_conjug_rep%3B FinO bacterial conjugation repressor domain%3B the basic protein FinO is part of the the two component FinOP system which is responsible for repressing bacterial conjugation gene gene-YerA41_119 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_119 YerA41_120 YerA41_120 YerA41_120 64887 65408 + structural protein gene gene-YerA41_120 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_120 YerA41_121 YerA41_121 YerA41_121 65422 65976 + hypothetical protein gene gene-YerA41_121 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_121 YerA41_122 YerA41_122 YerA41_122 65978 66394 + hypothetical protein gene gene-YerA41_122 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_122 YerA41_123 YerA41_123 YerA41_123 66465 67070 + structural protein gene gene-YerA41_123 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_123 YerA41_124 YerA41_124 YerA41_124 67160 67366 + hypothetical protein gene gene-YerA41_124 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_124 YerA41_125 YerA41_125 YerA41_125 67501 67812 + hypothetical protein weak similarity to cd07030%3B RNAP_D%3B D subunit of Archaeal RNA polymerase. The D subunit of archaeal RNA polymerase (RNAP) is involved in the assembly of RNAP subunits gene gene-YerA41_125 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_125 YerA41_126 YerA41_126 YerA41_126 67831 68172 + hypothetical protein weak similarity to cd10912%3B PIN_YacP-like%3B PIN_domain of Bacillus subtilis YacP/Rae1 and related proteins. Bacillus subtilis YacP%2C also known as Rae1%2C is an endoribonuclease involved in ribosome-dependent mRNA decay gene gene-YerA41_126 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_126 YerA41_127 YerA41_127 YerA41_127 68280 70193 + DNA ligase cd00114%3B LIGANc%3B NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication%2C repair and recombination%2C utilizing either ATP or NAD(+) as a cofactor%2C but using the same basic reaction mechanism. cd07901%3B Adenylation_DNA_ligase_Arch_LigB%3B Adenylation domain of archaeal and bacterial LigB-like DNA ligases. ATP-dependent polynucleotide ligases catalyze phosphodiester bond formation using nicked nucleic acid substrates with the high energy nucleotide of ATP as a cofactor in a three step reaction mechanism%3B structural protein%2C DNA ligase gene gene-YerA41_127 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_127 YerA41_128 YerA41_128 YerA41_128 70247 70444 + hypothetical protein weak similarity to cd01949%3B GGDEF%3B Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern%2C and initially described as a domain of unknown function 1 (DUF1) gene gene-YerA41_128 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_128 YerA41_129 YerA41_129 YerA41_129 70423 70689 + hypothetical protein weak similarity to cd00433%3B Peptidase_M17%3B Cytosol aminopeptidase family%2C N-terminal and catalytic domains. Family M17 contains zinc- and manganese-dependent exopeptidases (EC 3 gene gene-YerA41_129 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_129 YerA41_130 YerA41_130 YerA41_130 70752 71453 + endonuclease cd10446%3B GIY-YIG_unchar_1%3B GIY-YIG domain of uncharacterized hypothetical protein found in bacteria. The family includes a group of uncharacterized bacterial hypothetical proteins with a GIY-YIG domain that shows statistically significant similarity to the N-terminal catalytic domains of GIY-YIG family of intron-encoded homing endonuclease I-TevI and catalytic GIY-YIG domain of nucleotide excision repair endonuclease UvrC gene gene-YerA41_130 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_130 YerA41_131 YerA41_131 YerA41_131 71456 73483 + DNA topoisomerase III cd00186%3B TOP1Ac%3B DNA Topoisomerase%2C subtype IA%3B DNA-binding%2C ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III%2C and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases gene gene-YerA41_131 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_131 YerA41_132 YerA41_132 YerA41_132 73493 73852 + hypothetical protein weak similarity to cd17127%3B Ubl_TBK1%3B ubiquitin-like (Ubl) domain found in TRAF family member-associated NF-kappaB activator (TANK)-binding kinase 1 (TBK1) gene gene-YerA41_132 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_132 YerA41_133 YerA41_133 YerA41_133 73870 74226 + hypothetical protein some similarity to cd07999%3B GH7_CBH_EG%3B Glycosyl hydrolase family 7. Glycosyl hydrolase family 7 contains eukaryotic endoglucanases (EGs) and cellobiohydrolases (CBHs) that hydrolyze glycosidic bonds using a double-displacement mechanism gene gene-YerA41_133 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_133 YerA41_134 YerA41_134 YerA41_134 74367 75812 + DNA helicase cd09708%3B Csf4_U%3B CRISPR/Cas system-associated DinG family helicase Csf4. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA%3B structural protein%2C DNA helicase gene gene-YerA41_134 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_134 YerA41_135 YerA41_135 YerA41_135 75865 75972 + hypothetical protein Some similarity to cd04451%3B S1_IF1%3B S1_IF1: Translation Initiation Factor IF1%2C S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain%2C which is found in a wide variety of RNA-associated proteins. cd00267%3B ABC_ATPase%3B ATP-binding cassette transporter nucleotide-binding domain. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds%2C like sugars%2C ions%2C peptides%2C and more complex organic molecules. cd04114%3B Rab30%3B Rab GTPase family 30 (Rab30). Rab30 subfamily. Rab30 appears to be associated with the Golgi stack. cd04466%3B S1_YloQ_GTPase%3B S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA)%2C S1-like RNA-binding domain gene gene-YerA41_135 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_135 YerA41_136 YerA41_136 YerA41_136 75962 76597 + hypothetical protein gene gene-YerA41_136 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_136 YerA41_137 YerA41_137 YerA41_137 76608 78278 + RNA polymerase beta subunit cd01609%3B RNAP_beta'_N%3B Largest subunit (beta') of bacterial DNA-dependent RNA polymerase (RNAP)%2C N-terminal domain. cd02582%3B RNAP_archeal_A'%3B A' subunit of archaeal RNA polymerase (RNAP). A' is the largest subunit of the archaeal RNA polymerase (RNAP)%3B structural protein%2C RNAP beta-subunit gene gene-YerA41_137 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_137 YerA41_138 YerA41_138 YerA41_138 78275 79831 + RNA polymerase beta subunit cd02655%3B RNAP_beta'_C%3B Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP)%2C C-terminal domain. cd01609%3B RNAP_beta'_N%3B Largest subunit (beta') of bacterial DNA-dependent RNA polymerase (RNAP)%2C N-terminal domain. cd02584%3B RNAP_II_Rpb1_C%3B Largest subunit (Rpb1) of Eukaryotic RNA polymerase II (RNAP II)%2C C-terminal domain. cd02582%3B RNAP_archeal_A'%3B A' subunit of archaeal RNA polymerase (RNAP). A' is the largest subunit of the archaeal RNA polymerase (RNAP)%3B structural protein%2C RNAP beta-subunit gene gene-YerA41_138 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_138 YerA41_139 YerA41_139 YerA41_139 79898 82672 + RNA polymerase beta subunit cd00653%3B RNA_pol_B_RPB2%3B RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA%3B structural protein%2C RNAP beta subunit gene gene-YerA41_139 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_139 YerA41_140 YerA41_140 YerA41_140 82673 82909 + hypothetical protein some similarity to cd01474%3B vWA_ATR%3B ATR (Anthrax Toxin Receptor): Anthrax toxin is a key virulence factor for Bacillus anthracis%2C the causative agent of anthrax gene gene-YerA41_140 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_140 YerA41_141 YerA41_141 YerA41_141 82906 83913 + phosphoribosyltransferase cd06223%3B PRTases_typeI%3B Phosphoribosyl transferase (PRT)-type I domain. Phosphoribosyl transferase (PRT) domain%3B structural protein%2C Phosphoribosyltransferase gene gene-YerA41_141 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_141 YerA41_142 YerA41_142 YerA41_142 83916 84419 + hypothetical protein gene gene-YerA41_142 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_142 YerA41_143 YerA41_143 YerA41_143 84447 85130 + phosphohydrolase cd00077%3B HDc Metal dependent phosphohydrolases withconserved 'HD' motif. cd09712%3B Cas10d_I-D%3B CRISPR/Cassystem-associated protein Cas10d. CRISPR (ClusteredRegularly Interspaced Short Palindromic Repeats) andassociated Cas proteins comprise a system for heritablehost defense by prokaryotic cells against phage and otherforeign DNA gene gene-YerA41_143 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_143 YerA41_144 YerA41_144 YerA41_144 85132 89052 + DNA polymerase C-terminal 300 residues similar to cd08638%3B DNA_pol_A_theta%3B DNA polymerase theta is a low-fidelity family A enzyme implicated in translesion synthesis and in somatic hypermutation%3B contains also similarity to cd06140%3B DNA_polA_I_Bacillus_like_exo%3B inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases%3B structural protein%2C DNA polymerase gene gene-YerA41_144 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_144 YerA41_145 YerA41_145 YerA41_145 89111 89950 + hypothetical protein similarity to cd00489%3B Barstar_like%3B Barstar is an intracellular inhibitor of barnase%2C an extracellular ribonuclease of Bacillus amyloliquefaciens. cd05140%3B Barstar_AU1054-like%3B Barstar_AU1054-like contains uncharacterized sequences similar to the uncharacterized%2C predicted RNAase inhibitor AU1054 found in Burkholderia cenocepacia gene gene-YerA41_145 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_145 YerA41_146 YerA41_146 YerA41_146 89947 90645 + putative deoxyribonucleoside kinase cd01673%3B dNK%3B Deoxyribonucleoside kinase (dNK) catalyzes the phosphorylation of deoxyribonucleosides to yield corresponding monophosphates (dNMPs). cd02023%3B UMPK%3B Uridine monophosphate kinase (UMPK)%2C also known as uridine kinase or uridine-cytidine kinase (UCK)%2C catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. cd01672%3B TMPK%3B Thymidine monophosphate kinase (TMPK)%2C also known as thymidylate kinase%2C catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor gene gene-YerA41_146 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_146 YerA41_147 YerA41_147 YerA41_147 90645 91757 + putative glucosyltransferase cd16440%3B beta_Kdo_transferase_KpsC_1%3B beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsC%2C repeat1. KpsC is a beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase gene gene-YerA41_147 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_147 YerA41_148 YerA41_148 YerA41_148 91797 92570 + dehydrogenase Very stron similarity to conserved domains of cd05330%3B cyclohexanol_reductase_SDR_c%3B cyclohexanol reductases%2C including levodione reductase%2C classical (c) SDRs. Cyloclohexanol reductases%2Cincluding (6R)-2%2C2%2C6-trimethyl-1%2C4-cyclohexanedione (levodione) reductase of Corynebacterium aquaticum%2C catalyze the reversible oxidoreduction of hydroxycyclohexanone derivatives. cd05345%3B BKR_3_SDR_c%3B putative beta-ketoacyl acyl carrier protein [ACP] reductase (BKR)%2C subgroup 3%2C classical (c) SDR. cd08943%3B R1PA_ADH_SDR_c%3B rhamnulose-1-phosphate aldolase/alcohol dehydrogenase%2C classical (c) SDRs. This family has bifunctional proteins with an N-terminal aldolase and a C-terminal classical SDR domain. cd05329%3B TR_SDR_c%3B tropinone reductase-I and II (TR-1%2C and TR-II)-like%2C classical (c) SDRs. This subgroup includes TR-I and TR-II. cd05352%3B MDH-like_SDR_c%3B mannitol dehydrogenase (MDH)-like%2C classical (c) SDRs. NADP-mannitol dehydrogenase catalyzes the conversion of fructose to mannitol%2C an acyclic 6-carbon sugar gene gene-YerA41_148 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_148 YerA41_149 YerA41_149 YerA41_149 92573 93265 + ketoreductase or glucose dehydrogenase cd08945%3B PKR_SDR_c%3B Polyketide ketoreductase%2C classical (c) SDR. Polyketide ketoreductase (KR) is a classical SDR with a characteristic NAD-binding pattern and active site tetrad. cd05358%3B GlcDH_SDR_c%3B glucose 1 dehydrogenase (GlcDH)%2C classical (c) SDRs. GlcDH%2C is a tetrameric member of the SDR family%2C it catalyzes the NAD(P)-dependent oxidation of beta-D-glucose to D-glucono-delta-lactone gene gene-YerA41_149 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_149 YerA41_150 YerA41_150 YerA41_150 93295 93990 + putative carbohydrate esterase some similarity to cd10969%3B CE4_Ecf1_like_5s%3B Putative catalytic NodB homology domain of a hypothetical protein Ecf1 from Escherichia coli and similar proteins. d10930%3B CE4_u6%3B Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily gene gene-YerA41_150 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_150 YerA41_151 YerA41_151 YerA41_151 93990 95357 + 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase N-terminal domain similar to cd02516 CDP-ME_synthetase%3B CDP-ME synthetase is involved in mevalonate-independent isoprenoid ##production. 4-diphosphocytidyl-2-methyl-D-erythritol synthase (CDP-ME)%2C also called 2C-methyl-d-erythritol 4-phosphate cytidylyltransferase catalyzes the third step in the alternative (non-mevalonate) pathway of Isopentenyl diphosphate (IPP) biosynthesis: the formation of 4-diphosphocytidyl-2C-methyl-D-erythritol from CTP and 2C-methyl-D-erythritol 4-phosphate. cd02513%3B CMP-NeuAc_Synthase%3B CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety. CMP-N-acetylneuraminic acid synthetase (CMP-NeuAc synthetase) or acylneuraminate cytidylyltransferase catalyzes the transfer the CMP moiety of CTP to the anomeric hydroxyl group of NeuAc in the presence of Mg++. cd02517%3B CMP-KDO-Synthetase%3B CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide%3B C-terminal domain similar to cd05329%3B TR_SDR_c%3B tropinone reductase-I and II (TR-1%2C and TR-II)-like%2C classical (c) SDRs. This subgroup includes TR-I and TR-II. cd05330%3B cyclohexanol_reductase_SDR_c%3B cyclohexanol reductases%2C including levodione reductase%2C classical (c) SDRs. Cyloclohexanol reductases%2Cincluding (6R)-2%2C2%2C6-trimethyl-1%2C4-cyclohexanedione (levodione) reductase of Corynebacterium aquaticum%2C catalyze the reversible oxidoreduction of hydroxycyclohexanone derivatives. cd05352%3B MDH-like_SDR_c%3B mannitol dehydrogenase (MDH)-like%2C classical (c) SDRs. NADP-mannitol dehydrogenase catalyzes the conversion of fructose to mannitol%2C an acyclic 6-carbon sugar gene gene-YerA41_151 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_151 YerA41_152 YerA41_152 YerA41_152 95487 96668 + putative glycosyl(KDO)transferase cd16440%3B beta_Kdo_transferase_KpsC_1%3B beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsC%2C repeat1. KpsC is a beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase. cd16441%3B beta_Kdo_transferase_KpsS%3B beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase KpsS. KpsS is a beta-3-deoxy-D-manno-oct-2-ulosonic acid (Kdo)-transferase%3B structural protein%2C putative glycosyl (KDO)transferase gene gene-YerA41_152 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_152 YerA41_153 YerA41_153 YerA41_153 96668 97486 + glycerophosphodiesterase cd08606%3B GDPD_YPL110cp_fungi%3B Glycerophosphodiesterphosphodiesterase domain of Saccharomyces cerevisiaeYPL110cp and similar proteins. cd08568%3B GDPD_TmGDE_like%3BGlycerophosphodiester phosphodiesterase domain ofThermotoga maritime and similar proteins. cd08564%3BGDPD_GsGDE_like%3B Glycerophosphodiester phosphodiesterasedomain of putative Galdieria sulphurariaglycerophosphodiester phosphodiesterase and similarproteins gene gene-YerA41_153 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_153 YerA41_154 YerA41_154 YerA41_154 97487 98140 + structural protein gene gene-YerA41_154 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_154 YerA41_155 YerA41_155 YerA41_155 98140 98292 + hypothetical protein gene gene-YerA41_155 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_155 YerA41_156 YerA41_156 YerA41_156 98470 98790 + hypothetical protein weak similarity to cd12709%3B RRM_RCAN2%3B RNA recognition motif in vertebrate regulator of calcineurin 2 (RCAN2). This subgroup corresponds to the RRM of RCAN2%2C also termed calcipressin-2%2C or Down syndrome candidate region 1-like 1 (DSCR1L1)%2C or myocyte-enriched calcineurin-interacting protein 2 (MCIP2)%2C or thyroid hormone-responsive protein ZAKI-4%2C encoded by a novel thyroid hormone-responsive%3B ZAKI-4 that is abundantly expressed in human brain%2C heart and muscles gene gene-YerA41_156 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_156 YerA41_157 YerA41_157 YerA41_157 98857 99153 + hypothetical protein gene gene-YerA41_157 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_157 YerA41_158 YerA41_158 YerA41_158 99157 100053 + DNA polymerase X family protein cd00141%3B NT_POLXc%3B Nucleotidyltransferase (NT) domain of family X DNA Polymerases. X family polymerases fill in short gaps during DNA repair gene gene-YerA41_158 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_158 YerA41_159 YerA41_159 YerA41_159 100063 100284 + hypothetical protein weak similarity to cd14795%3B RNLA_N_2%3B N-terminal repeat domain of toxin RnlA%3B second out of two repeats. The Escherichia coli toxin RnlA functions as an mRNA endoribonuclease and is part of a two-component toxin-antitoxin system that promotes resistance to phage infections%2C together with the antitoxin RnlB gene gene-YerA41_159 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_159 YerA41_160 YerA41_160 YerA41_160 100307 102226 + structural protein gene gene-YerA41_160 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_160 YerA41_161 YerA41_161 YerA41_161 102219 102431 + hypothetical protein gene gene-YerA41_161 http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_161 YerA41_162c YerA41_162c YerA41_162c 102487 102996 - structural protein gene gene-YerA41_162c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_162c YerA41_163c YerA41_163c YerA41_163c 103007 103300 - hypothetical protein weak similarity to cd14653%3B ZIP_Gal4p-like%3B Leucinezipper Dimerization domain of Gal4p-like transcriptionfactors. The Gal4p family of transcriptional activatorscontain an N-terminal DNA-binding domain with a Zn2Cys6binuclear cluster that interact with CCG triplets and aleucine zipper-like heptad repeat that dimerizes gene gene-YerA41_163c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_163c YerA41_164c YerA41_164c YerA41_164c 103264 103725 - hypothetical protein gene gene-YerA41_164c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_164c YerA41_165c YerA41_165c YerA41_165c 103750 104283 - N-acetylmuramidase cd13926%3B N-acetylmuramidase_GH108%3B N-acetylmuramidase domain of the glycosyl hydrolase 108 family. This domain acts as a lysozyme (N-acetylmuramidase)%2C EC:3 gene gene-YerA41_165c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_165c YerA41_166c YerA41_166c YerA41_166c 104298 104639 - hypothetical protein weak similarity to cd15261%3B 7tmB1_PDFR%3B The pigmentdispersing factor receptor%2C member of the class Bseven-transmembrane G protein-coupled receptors. cd15266%3B7tmB1_GLP2R%3B glucagon-like peptide-2 receptor%2C member ofthe class B family of seven-transmembrane Gprotein-coupled receptors gene gene-YerA41_166c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_166c YerA41_167c YerA41_167c YerA41_167c 104644 104931 - hypothetical protein weak similarity to cd11744%3B MIT_CorA-like%3B metal ion transporter CorA-like divalent cation transporter superfamily. This superfamily of essential membrane proteins is involved in transporting divalent cations (uptake or efflux) across membranes. cd12837%3B EcCorA-like_u1%3B uncharacterized subgroup of the Escherichia coli Mg2+ transporter CorA_like subfamily gene gene-YerA41_167c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_167c YerA41_168c YerA41_168c YerA41_168c 104953 105279 - hypothetical protein weak similarity to cd02435%3B CCC1%3B CCC1. CCC1: This domain is present in the CCC1%2C an iron and manganese transporter of Saccharomyces cerevisiae gene gene-YerA41_168c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_168c YerA41_169c YerA41_169c YerA41_169c 105291 106031 - tail fiber protein gene gene-YerA41_169c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_169c YerA41_170c YerA41_170c YerA41_170c 106092 106715 - tail fiber assembly protein gene gene-YerA41_170c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_170c YerA41_171c YerA41_171c YerA41_171c 106986 108146 - structural protein gene gene-YerA41_171c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_171c YerA41_172c YerA41_172c YerA41_172c 108160 109245 - tail fiber protein gene gene-YerA41_172c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_172c YerA41_173c YerA41_173c YerA41_173c 109258 109572 - hypothetical protein gene gene-YerA41_173c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_173c YerA41_174c YerA41_174c YerA41_174c 109583 109990 - hypothetical protein gene gene-YerA41_174c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_174c YerA41_175c YerA41_175c YerA41_175c 110025 110522 - hypothetical protein gene gene-YerA41_175c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_175c YerA41_176c YerA41_176c YerA41_176c 110536 112152 - hypothetical protein gene gene-YerA41_176c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_176c YerA41_177c YerA41_177c YerA41_177c 112170 113825 - structural protein gene gene-YerA41_177c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_177c YerA41_178c YerA41_178c YerA41_178c 113831 114199 - hypothetical protein Weak similarity to ribosome-tRNA interaction inhibitor. cd00552%3B RaiA%3B RaiA (ribosome-associated inhibitor A)%2C also known as Protein Y (PY)%2C YfiA%2C and SpotY%2C is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal A site gene gene-YerA41_178c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_178c YerA41_179c YerA41_179c YerA41_179c 114273 114560 - PAAR domain containing protein cd14742%3B PAAR_RHS%3B proline-alanine-alanine-arginine(PAAR) domain%2C also containing C-terminal Rearrangementhotspot (Rhs) extensions. cd14737%3B PAAR_1%3Bproline-alanine-alanine-arginine (PAAR) domain. Thisdomain is found in the PAAR(proline-alanine-alanine-arginine) repeat family%2C where itforms a sharp conical extension on the VgrG spike%2C atrimeric protein complex of the bacterial type VIsecretion system (T6SS). cd14744%3B PAAR_CT_2%3Bproline-alanine-alanine-arginine (PAAR) domain withuncharacterized C-terminal extension gene gene-YerA41_179c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_179c YerA41_180c YerA41_180c YerA41_180c 114570 115301 - hypothetical protein gene gene-YerA41_180c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_180c YerA41_181c YerA41_181c YerA41_181c 115314 117485 - hypothetical protein gene gene-YerA41_181c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_181c YerA41_182c YerA41_182c YerA41_182c 117503 117874 - structural protein gene gene-YerA41_182c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_182c YerA41_183c YerA41_183c YerA41_183c 117883 118986 - structural protein gene gene-YerA41_183c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_183c YerA41_184c YerA41_184c YerA41_184c 118983 119306 - hypothetical protein gene gene-YerA41_184c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_184c YerA41_185c YerA41_185c YerA41_185c 119309 119974 - hypothetical protein weak similarity to cd01278%3B aprataxin_related%3B aprataxin related: Aprataxin%2C a HINT family hydrolase is mutated in ataxia oculomotor apraxia syndrome gene gene-YerA41_185c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_185c YerA41_186c YerA41_186c YerA41_186c 119986 123117 - putative tail protein contains the conserved domain cd00978%3B chitosanase_GH46%3B chitosanase belonging to the glycosyl hydrolase 46 family. This family is composed of the chitosanase enzymes which hydrolyzes chitosan%2C a biopolymer of beta (1%2C4)-linked-D-glucosamine (GlcN) residues produced by partial or full deacetylation of chitin%3B putative tail protein (ACLAME 1)%2C chitosanase%3B putative tail protein gene gene-YerA41_186c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_186c YerA41_187c YerA41_187c YerA41_187c 123271 124026 - hypothetical protein weak similarity to Zn-ribbon domain%2C RNA polymeraseassociated cd13946%3B LysW%3B Lysine biosynthesis proteinLysW. LysW functions as a carrier protein in thebiosynthesis pathway of lysine. cd10508%3B Zn-ribbon_RPB9%3BC-terminal zinc ribbon domain of RPB9 subunit of RNApolymerase II. The C-terminal zinc ribbon domain(C_ribbon) of subunit B9 (C-ribbon_RPB9) in RNA polymerase(Pol) II is involved in intrinsic transcript cleavage gene gene-YerA41_187c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_187c YerA41_188c YerA41_188c YerA41_188c 124026 124601 - hypothetical protein gene gene-YerA41_188c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_188c YerA41_189c YerA41_189c YerA41_189c 124625 125164 - hypothetical protein gene gene-YerA41_189c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_189c YerA41_190c YerA41_190c YerA41_190c 125181 127763 - structural protein gene gene-YerA41_190c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_190c YerA41_191c YerA41_191c YerA41_191c 127806 127991 - hypothetical protein gene gene-YerA41_191c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_191c YerA41_192c YerA41_192c YerA41_192c 128005 128748 - structural protein gene gene-YerA41_192c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_192c YerA41_193c YerA41_193c YerA41_193c 128745 129344 - structural protein gene gene-YerA41_193c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_193c YerA41_194c YerA41_194c YerA41_194c 129360 129926 - hypothetical protein gene gene-YerA41_194c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_194c YerA41_195c YerA41_195c YerA41_195c 129933 130448 - structural protein Weak similarity to C-terminal helix-turn-helix typeDNA binding domain. cd06571%3B Bac_DnaA_C%3B C-terminal domainof bacterial DnaA proteins. The DNA-binding C-terminaldomain of DnaA contains a helix-turn-helix motif thatspecifically interacts with the DnaA box%2C a 9-mer motifthat occurs repetitively in the replication origin oriC.cd04762%3B HTH_MerR-trunc%3B Helix-Turn-Helix DNA bindingdomain of truncated MerR-like proteins. Proteins in thisfamily mostly have a truncated helix-turn-helix (HTH)MerR-like domain gene gene-YerA41_195c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_195c YerA41_196c YerA41_196c YerA41_196c 130441 131370 - hypothetical protein gene gene-YerA41_196c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_196c YerA41_197c YerA41_197c YerA41_197c 131390 131731 - structural protein cd17470%3B T3SS_Flik_C%3B C-terminal domain of flagellar hook-length control protein FliK and similar domains. cd17467%3B T3SS_YscP_C%3B C-terminal substrate-switching domain of ruler proteins from the Ysc family%2C such as YscP and PscP. cd17468%3B T3SS_HrpP_C%3B C-terminal domain of type III secretion protein HrpP and similar domains. This subfamily contains Pseudomonas syringae HrpP%2C a type III secretion system (T3SS) substrate specificity switch-domain protein that has has an atypical T3SS translocation signal gene gene-YerA41_197c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_197c YerA41_198c YerA41_198c YerA41_198c 131735 132634 - structural protein gene gene-YerA41_198c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_198c YerA41_199c YerA41_199c YerA41_199c 132667 133524 - hypothetical protein Some similarity to Zink ribbon domain in RNA polymerases. cd10511%3B Zn-ribbon_TFS%3B C-terminal zinc ribbon domain of archaeal Transcription Factor S (TFS). TFS is an archaeal protein that stimulates the intrinsic cleavage activity of archaeal RNA polymerase. cd10509%3B Zn-ribbon_RPC11%3B C-terminal zinc ribbon domain of RPC11 subunit of RNA polymerase III. The C-terminal zinc ribbon domain (C_ribbon) of subunit C11 (C-ribbon_RPC11) in RNA polymerase (Pol) III is required for intrinsic transcript cleavage gene gene-YerA41_199c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_199c YerA41_200c YerA41_200c YerA41_200c 133611 135026 - structural protein gene gene-YerA41_200c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_200c YerA41_201c YerA41_201c YerA41_201c 135123 136328 - structural protein Strong similarity to cd07623%3B BAR_SNX1_2%3B The Bin/Amphiphysin/Rvs (BAR) domain of Sorting Nexins 1 and 2. BAR domains are dimerization%2C lipid binding and curvature sensing modules found in many different proteins with diverse functions gene gene-YerA41_201c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_201c YerA41_202c YerA41_202c YerA41_202c 136338 137096 - structural protein Very weak hit on RNAse. cd00606%3B fungal_RNase%3B fungal type ribonuclease. Ribonucleases (RNAses) cleave phosphodiester bonds in RNA and are essential for both non-specific RNA degradation and for numerous forms of RNA processing gene gene-YerA41_202c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_202c YerA41_203c YerA41_203c YerA41_203c 137178 138047 - structural protein gene gene-YerA41_203c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_203c YerA41_204c YerA41_204c YerA41_204c 138093 139643 - structural protein gene gene-YerA41_204c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_204c YerA41_205c YerA41_205c YerA41_205c 139741 140082 - structural protein gene gene-YerA41_205c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_205c YerA41_206c YerA41_206c YerA41_206c 140085 140495 - structural protein Weak similarity to cd02968%3B SCO%3B SCO (an acronym for Synthesis of Cytochrome c Oxidase) family%3B composed of proteins similar to Sco1%2C a membrane-anchored protein possessing a soluble domain with a TRX fold gene gene-YerA41_206c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_206c YerA41_207c YerA41_207c YerA41_207c 140513 142381 - DEXH-box RNA or DNA helicase cd17921%3B DEXHc_Ski2%3B DEXH-box helicase domain of DEAD-like helicase Ski2 family proteins. Ski2-like RNA helicases play an important role in RNA degradation%2C processing%2C and splicing pathways. cd18031%3B DEXHc_UvsW%3B DEXH-box helicase domain of bacteriophage UvsW. Bacteriophage UvsW is part of the WXY system that repairs DNA damage by a process that involves homologous recombination%3B structural protein%2C DEXH-box RNA or DNA helicase gene gene-YerA41_207c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_207c YerA41_208c YerA41_208c YerA41_208c 142561 142959 - structural protein Weak similarity to Cas2. cd09725%3B Cas2_I_II_III%3B CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA gene gene-YerA41_208c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_208c YerA41_209c YerA41_209c YerA41_209c 142969 143442 - structural protein gene gene-YerA41_209c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_209c YerA41_210c YerA41_210c YerA41_210c 143452 143979 - hypothetical protein weak similarity to cd12542%3B RRM2_LARP7%3B RNA recognition motif 2 in La-related protein 7 (LARP7) and similar proteins. This subgroup corresponds to the RRM2 of LARP7%2C also termed La ribonucleoprotein domain family member 7%2C or P-TEFb-interaction protein for 7SK stability (PIP7S)%2C an oligopyrimidine-binding protein that binds to the highly conserved 3'-terminal U-rich stretch (3' -UUU-OH) of 7SK RNA gene gene-YerA41_210c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_210c YerA41_211c YerA41_211c YerA41_211c 143993 144298 - structural protein gene gene-YerA41_211c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_211c YerA41_212c YerA41_212c YerA41_212c 144312 144626 - structural protein weak similarity to cd18802%3B SF2_C_dicer%3B C-terminalhelicase domain of the endoribonuclease Dicer. Dicerribonucleases cleave double-stranded RNA (dsRNA)precursors to generate microRNAs (miRNAs) and smallinterfering RNAs (siRNAs) gene gene-YerA41_212c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_212c YerA41_213c YerA41_213c YerA41_213c 144613 145203 - hypothetical protein gene gene-YerA41_213c http://www.ncbi.nlm.nih.gov/gene/?term=YerA41_213c