locus-tag class description BZ23_1 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ23_10 ENOG4108M8S permease YjgP YjgQ family protein BZ23_100 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BZ23_1000 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ23_1002 ENOG4105VEQ Cold shock protein BZ23_1004 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ23_1005 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BZ23_1007 ENOG4108JJ8 (ABC) transporter BZ23_1008 ENOG4108JJ9 ABC, transporter BZ23_1009 ENOG4105C3M thioredoxin reductase BZ23_101 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BZ23_1010 ENOG4105EW9 transcriptional regulator AsnC family BZ23_1011 ENOG4105CNU cell division protein FtsK BZ23_1014 ENOG4105D1H recombination factor protein RarA BZ23_1016 ENOG4108ISG Major Facilitator BZ23_1017 ENOG4105F1A Pyruvate formate-lyase BZ23_1019 ENOG4105C6N Formate acetyltransferase BZ23_102 ENOG4108NIW Leucine export protein LeuE BZ23_1020 ENOG4105TMB Formate nitrite transporter BZ23_1021 ENOG4105DDY UPF0142 protein ycaO BZ23_1022 ENOG4105HDK L-asparaginase BZ23_1028 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BZ23_103 ENOG4105DWK Membrane BZ23_1030 ENOG4108RS6 transposase BZ23_1032 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BZ23_1035 ENOG4105E32 cytoplasmic protein BZ23_1036 ENOG4105VEQ Cold shock protein BZ23_1037 ENOG4105W49 UPF0434 protein BZ23_1039 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups BZ23_1040 ENOG4106371 Methyltransferase BZ23_1041 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) BZ23_1042 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) BZ23_1044 ENOG4105DIT ErfK YbiS YcfS YnhG family protein BZ23_1045 ENOG4105EAQ (twin-arginine translocation) pathway signal BZ23_1046 ENOG4105C5X domain protein BZ23_1047 ENOG4105CGF Aromatic amino acid aminotransferase BZ23_105 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BZ23_1051 ENOG4105CD8 aminopeptidase N BZ23_1053 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) BZ23_1054 ENOG4105QVC MOSC domain-containing protein BZ23_1056 ENOG4105C5H ABC transporter BZ23_1057 ENOG4105F1S paraquat-inducible protein a BZ23_1058 ENOG4105DY2 Paraquat-inducible protein b BZ23_1059 ENOG4108Q2G (LipO)protein BZ23_1060 ENOG4108RS6 transposase BZ23_1061 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ23_1064 ENOG4105DAN ATP-dependent protease BZ23_1066 ENOG4105UYK outer membrane protein a BZ23_1068 ENOG4108RZ1 DNA transformation protein BZ23_1069 ENOG4105EM2 membrane BZ23_1070 ENOG410901E Membrane BZ23_1071 ENOG41088T4 Helicase IV BZ23_1073 ENOG4108Q67 UPF0319 protein BZ23_1074 ENOG4105K4P CoA-binding domain protein BZ23_1078 ENOG4108Z0T Part of a sulfur-relay system (By similarity) BZ23_1081 ENOG4108BUD transposase BZ23_1087 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BZ23_1088 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ23_1089 ENOG4105CHR reductase BZ23_1090 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BZ23_1092 ENOG4108KQ6 Enoyl-CoA hydratase BZ23_1093 ENOG4105CHR reductase BZ23_1095 ENOG41062T2 Acyl carrier protein BZ23_1096 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ23_11 ENOG4108K5H permease YjgP YjgQ family protein BZ23_1101 ENOG4105CDV Ompa motb domain protein BZ23_1103 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ23_111 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BZ23_1122 ENOG4105C5H ABC transporter BZ23_1125 ENOG4105D06 uba thif-type nad fad binding protein BZ23_1126 ENOG4105CVM Molybdenum cofactor synthesis domain protein BZ23_1129 ENOG4105C19 ABC transporter BZ23_1130 ENOG4105ENT Efflux transporter rnd family, mfp subunit BZ23_1135 ENOG4105EGI Transcriptional regulator BZ23_1136 ENOG4105CBP Major Facilitator BZ23_1138 ENOG4105DHF Membrane BZ23_114 ENOG4105D3G Pseudouridine synthase BZ23_1141 ENOG4108HWV )-transporter BZ23_1142 ENOG4107GZ4 SanA protein BZ23_1145 ENOG41067MG lrgb family BZ23_1147 ENOG4105E5W Transporter BZ23_1152 ENOG4105D1F ATP-binding protein BZ23_1155 ENOG4108GAE asmA family BZ23_1156 ENOG4105EE5 Membrane protein terC BZ23_1157 ENOG4108819 ferric iron reductase BZ23_1158 ENOG4105DY8 decarboxylase BZ23_1159 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ23_1161 ENOG4105DUU IucA IucC family protein BZ23_1162 ENOG4105E0A ABC, transporter BZ23_1163 ENOG4105TVJ transport system, permease BZ23_1164 ENOG4105DQ5 transport system permease protein BZ23_1165 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BZ23_1166 ENOG4105CNM Receptor BZ23_1167 ENOG4105DUU IucA IucC family protein BZ23_1168 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ23_1169 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ23_1170 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BZ23_1171 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BZ23_1174 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BZ23_1177 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BZ23_1179 ENOG4108535 NAD dependent epimerase/dehydratase family BZ23_1182 ENOG4105CNN ABC, transporter BZ23_1183 ENOG4105C2J ABC transporter BZ23_1184 ENOG4107SCQ Iron-containing alcohol dehydrogenase BZ23_1186 ENOG4105CUB amino acid BZ23_1187 ENOG4105CJB Exodeoxyribonuclease I BZ23_1190 ENOG4105TNG K13735 adhesin invasin BZ23_1191 ENOG4105CSP Major Facilitator Superfamily BZ23_1192 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BZ23_1193 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BZ23_1195 ENOG4105DIA mandelate racemase muconate lactonizing BZ23_1199 ENOG4105UQX Mate efflux family protein BZ23_1203 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BZ23_1213 ENOG4107ZSV Receptor BZ23_1214 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BZ23_1218 ENOG4105C0W non-ribosomal peptide synthetase BZ23_1221 ENOG4105BZ1 (ABC) transporter BZ23_1222 ENOG4105EYM Major Facilitator superfamily BZ23_1226 ENOG4108KX4 response regulator BZ23_1227 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BZ23_1229 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BZ23_123 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ23_1230 ENOG4108TSE Transferase BZ23_1234 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BZ23_124 ENOG4105CS6 Rhs element vgr protein BZ23_1240 ENOG4105BZ1 (ABC) transporter BZ23_1244 ENOG4105N4N Protein of unknown function (DUF2766) BZ23_1245 ENOG4105TIK BZ23_1246 ENOG41064PC BZ23_1249 ENOG4105C85 amino acid BZ23_1252 ENOG4105VEQ Cold shock protein BZ23_1253 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ23_1254 ENOG4105DHI Methyltransferase BZ23_1256 ENOG4105BZU Histidine kinase BZ23_1260 ENOG4105F3R pts system mannose fructose sorbose family iid BZ23_1261 ENOG4105ETZ PTS System BZ23_1262 ENOG4108EQA pts system BZ23_1263 ENOG4105EE5 Membrane protein terC BZ23_1264 ENOG4108V8F Transcriptional regulator, MarR family BZ23_1267 ENOG4105C26 Dehydrogenase BZ23_1268 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase BZ23_1273 ENOG4105EFA 4-hydroxyphenylacetate BZ23_1274 ENOG4107UWN reductase BZ23_1275 ENOG4105EJQ L-serine dehydratase BZ23_1277 ENOG4105CRQ synthase (Component I) BZ23_1280 ENOG4105C1J atp-dependent rna helicase BZ23_1281 ENOG4105X2V dna damage-inducible protein BZ23_1284 ENOG4105CUG Oligopeptidase b BZ23_1286 ENOG4105MPK DNA polymerase III subunit theta BZ23_1287 ENOG41090A1 ferritin BZ23_1288 ENOG4105FXM Copper resistance protein BZ23_1290 ENOG4105NKT exported protein BZ23_1297 ENOG4105D00 flagellar biosynthetic protein flhB BZ23_1298 ENOG4105D7B Flagellar biosynthesis protein flha BZ23_1299 ENOG4105W13 flagellar protein BZ23_1301 ENOG4105QVD Flagella synthesis protein FlgN BZ23_1302 ENOG4105M9M anti-sigma28 factor FlgM BZ23_1303 ENOG4105CKS Flagella basal body P-ring formation protein flgA BZ23_1304 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ23_1305 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ23_1306 ENOG4105W00 Flagellar hook capping protein BZ23_1307 ENOG4105BZE flagellar hook protein, FlgE BZ23_1309 ENOG4105BZE flagellar hook protein, FlgE BZ23_1310 ENOG4108KPB Flagellar basal-body rod protein FlgF BZ23_1311 ENOG4105CGA flagellar basal-body rod protein FlgG BZ23_1314 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BZ23_1315 ENOG4105E1Q flagellar hook-associated protein BZ23_1316 ENOG4105DTJ flagellar hook-associated protein BZ23_1317 ENOG4105DKT Transcriptional regulator BZ23_1319 ENOG4105CNN ABC, transporter BZ23_1321 ENOG4105C2J ABC transporter BZ23_1322 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BZ23_1323 ENOG4108MGF sugar kinase BZ23_1326 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ23_1327 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ23_1328 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ23_1330 ENOG4105DD5 Flagellar motor switch protein BZ23_1331 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ23_1332 ENOG4107ZI8 flagellar basal body-associated protein flil BZ23_1333 ENOG4105WF4 Flagellar hook-length control protein BZ23_1334 ENOG4105GSA Flagellar export protein flij BZ23_1335 ENOG4108JIR Flagellum-specific ATP synthase BZ23_1336 ENOG41090PJ Flagellar assembly protein BZ23_1337 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ23_1338 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ23_1339 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BZ23_1343 ENOG4105DHT Metal Dependent Phosphohydrolase BZ23_1346 ENOG4105MQ3 flagellar protein FliS BZ23_1347 ENOG4105DTS flagellar hook-associated BZ23_1348 ENOG4105I03 Flagellin BZ23_1349 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ23_135 ENOG4105CQ2 DNA polymerase BZ23_1350 ENOG4108M9K flagella biosynthesis protein FliZ BZ23_1352 ENOG4105EAB amino acid AbC transporter BZ23_1353 ENOG4105E5Q amino acid AbC transporter BZ23_1354 ENOG4105CDA abc transporter atp-binding protein BZ23_1357 ENOG4105C26 Dehydrogenase BZ23_1359 ENOG4105CK7 Sodium proline symporter BZ23_136 ENOG4108KF1 Membrane BZ23_1365 ENOG4105C85 amino acid BZ23_1367 ENOG4108T1M outer membrane protein x BZ23_1369 ENOG4105RA2 Membrane BZ23_1370 ENOG4105XVG cytoplasmic protein BZ23_1371 ENOG4105WH1 Two component transcriptional regulator luxr family BZ23_1377 ENOG4105ZTC transcriptional activator, Ogr delta BZ23_138 ENOG4106SMU thiamine transporter membrane protein BZ23_139 ENOG4105DP9 ABC transporter BZ23_1404 ENOG4105ED4 portal protein BZ23_1408 ENOG4105VZ1 Replication Protein BZ23_1410 ENOG4105DFE Dna adenine methylase BZ23_1411 ENOG4108IRC dna polymerase iii BZ23_142 ENOG4105CMM transposase BZ23_1426 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ23_1433 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ23_144 ENOG4105S8Q sugar efflux transporter BZ23_1463 ENOG4105FDP GntR family transcriptional regulator BZ23_1465 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BZ23_1468 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BZ23_1469 ENOG4108IJ9 (ABC) transporter BZ23_147 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BZ23_1471 ENOG4108MQF Chaperone BZ23_1473 ENOG4105CW0 outer membrane usher protein BZ23_1476 ENOG4105BZU Histidine kinase BZ23_1477 ENOG4108Q9V regulatoR BZ23_1478 ENOG4105CYC Transferase BZ23_1479 ENOG4105DJG MaoC domain protein dehydratase BZ23_1484 ENOG4107RGD Major Facilitator superfamily BZ23_1487 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ23_1488 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BZ23_1489 ENOG4105C85 amino acid BZ23_1490 ENOG4105MVE transcriptional regulator BZ23_1491 ENOG4105CSV Glutaminase BZ23_1493 ENOG4107SJW iron permease, FTR1 BZ23_1496 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BZ23_1498 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BZ23_15 ENOG4105DZR Type I site-specific deoxyribonuclease BZ23_150 ENOG41064T2 transcriptional regulator, lysR family BZ23_1502 ENOG4105H1N peptidase, M24 BZ23_1503 ENOG4108TUY outer membrane protein PgaA BZ23_1504 ENOG4107BJW polysaccharide deacetylase BZ23_1505 ENOG4105CND Glycosyl transferase, family 2 BZ23_1506 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD BZ23_1509 ENOG4105D5M phosphate starvation-inducible protein BZ23_151 ENOG4108IQE Amp-dependent synthetase and ligase BZ23_1510 ENOG4105EWV Sodium calcium exchanger membrane region BZ23_1511 ENOG4105BZU Histidine kinase BZ23_152 ENOG4105C7K acetolactate synthase BZ23_1524 ENOG4105CZE histidine utilization repressor BZ23_1525 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BZ23_1528 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BZ23_1529 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ23_153 ENOG4108ZP8 Acetolactate synthase small subunit BZ23_154 ENOG4107B7Y DNA-binding transcriptional regulator FruR BZ23_1542 ENOG4108WF3 methyltransferase BZ23_155 ENOG4108RNS Exports L-alanine (By similarity) BZ23_1550 ENOG4108RS6 transposase BZ23_1552 ENOG4105GR3 Histidine kinase BZ23_1554 ENOG4105ENX hydrolase BZ23_1558 ENOG4105C3G gtp-binding protein BZ23_1560 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria BZ23_1561 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BZ23_1566 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BZ23_1567 ENOG4108YY7 Invasion gene expression up-regulator SirB BZ23_1568 ENOG41063JG Transcriptional regulator BZ23_1570 ENOG4105CHH sulfate transporter BZ23_1574 ENOG4105EG2 ABC transporter, permease BZ23_1575 ENOG4105F38 ABC transporter, permease BZ23_1577 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BZ23_1578 ENOG4105E2R ROK family BZ23_158 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BZ23_1581 ENOG4107XHZ cytoplasmic chaperone TorD family protein BZ23_1582 ENOG4105F3T (LipO)protein BZ23_1584 ENOG4105D9U N-acetyltransferase BZ23_1587 ENOG4105CJR Integral membrane protein (MviN BZ23_159 ENOG4105CJN penicillin-binding protein BZ23_1591 ENOG4106ZCM YecM protein BZ23_1595 ENOG4105WJG Glutathione BZ23_1596 ENOG41081XQ Conserved Protein BZ23_1598 ENOG4108TIT dATP pyrophosphohydrolase BZ23_16 ENOG41082EK Restriction modification system DNA (Specificity BZ23_160 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BZ23_1603 ENOG4105FAV ABC, transporter BZ23_1605 ENOG4105NXV High-affinity zinc uptake system protein BZ23_1606 ENOG4105DR5 peptidase BZ23_1607 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BZ23_1608 ENOG4105CA9 Pyruvate kinase BZ23_1609 ENOG4106KNT transcriptional regulator BZ23_161 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BZ23_1610 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BZ23_1612 ENOG4108UHU Aldolase BZ23_1615 ENOG4105M4H endoribonuclease L-psp BZ23_1616 ENOG4105DVT helicase BZ23_1617 ENOG41072GX Peptidase M22 Glycoprotease BZ23_1618 ENOG4105Y4Z Outer Membrane Lipoprotein BZ23_1619 ENOG4105CEY Amp-dependent synthetase and ligase BZ23_1620 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BZ23_1621 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) BZ23_1622 ENOG4107QMS site-determining protein BZ23_1625 ENOG4105CVE Lytic murein transglycosylase BZ23_1626 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BZ23_1630 ENOG4105C3J Cysteine desulfurase BZ23_1636 ENOG4105ED1 spovr family BZ23_1638 ENOG4105CNH Multidrug resistance protein MdtL BZ23_1639 ENOG4105EUB pirin domain protein BZ23_164 ENOG4105CNI cell division protein FtsW BZ23_1640 ENOG4105HEI LysR family (Transcriptional regulator BZ23_1643 ENOG4105CYN Serine protein kinase BZ23_1644 ENOG4105GNX MltA-interacting MipA family protein BZ23_1645 ENOG4105DSB aldose 1-epimerase BZ23_1648 ENOG4105VUT cytoplasmic protein BZ23_1649 ENOG4108RWI nicotinamidase BZ23_1650 ENOG4105HDK L-asparaginase BZ23_1651 ENOG4105D07 Signal peptide peptidase, SppA BZ23_1652 ENOG41069NU Nitroreductase BZ23_1654 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ23_1655 ENOG4105MTM Protein of unknown function (DUF1496) BZ23_1656 ENOG4105M6F mutator MutT protein BZ23_1657 ENOG4105CGK Exodeoxyribonuclease III BZ23_1658 ENOG4105SKE transcriptional Regulator LysR family BZ23_1662 ENOG4105CIY formyltetrahydrofolate deformylase BZ23_1664 ENOG4105I93 response regulator BZ23_1665 ENOG4105C6Y Udp-glucose 6-dehydrogenase BZ23_1667 ENOG4107104 thymidine kinase BZ23_1668 ENOG4108EKI Dehydrogenase BZ23_1669 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BZ23_1670 ENOG4107QSI ABC, transporter BZ23_1672 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ23_1673 ENOG4105C3U ABC transporter BZ23_1674 ENOG4108JQ7 (ABC) transporter BZ23_1678 ENOG4108T1M outer membrane protein x BZ23_168 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BZ23_1681 ENOG4105K9H YciI-like protein BZ23_1683 ENOG410822N TonB family BZ23_1684 ENOG4105NAU thioesterase Superfamily protein BZ23_1688 ENOG4105EIF outer membrane protein W BZ23_169 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BZ23_1692 ENOG4105DK0 Indole-3-glycerol phosphate synthase BZ23_1694 ENOG4105DDQ anthranilate synthase BZ23_1696 ENOG4105DB7 PHP domain protein BZ23_1697 ENOG4107RTD sua5 ycio yrdc ywlc family protein BZ23_1698 ENOG4105FE9 pseudouridine synthase BZ23_1699 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BZ23_170 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BZ23_1700 ENOG4105UBK short-chain dehydrogenase reductase BZ23_1701 ENOG4105ERU peptidase BZ23_1702 ENOG4105RKX Protein of unknown function (DUF2498) BZ23_1704 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ23_1705 ENOG4108RS6 transposase BZ23_1706 ENOG4107R11 Transcriptional regulator BZ23_1708 ENOG4107QM5 aconitate hydratase BZ23_1709 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BZ23_1710 ENOG4105EYK Phosphatidylglycerophosphatase B BZ23_1711 ENOG4105Q4A inner membrane protein yciS BZ23_1712 ENOG4105CFV Tetratricopeptide repeat protein BZ23_1715 ENOG4108ZJT translation initiation factor, Sui1 BZ23_1716 ENOG41061RM osmotically inducible lipoprotein BZ23_1717 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ23_1719 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BZ23_1720 ENOG4105VCD cytoplasmic protein BZ23_1721 ENOG4105D22 carbon starvation protein BZ23_1723 ENOG4105CSP Major Facilitator Superfamily BZ23_1724 ENOG4105EXW epimerase dehydratase BZ23_1725 ENOG4105CSM endonuclease III BZ23_1727 ENOG4108UQQ Electron transport complex BZ23_1729 ENOG4105UEI Transcriptional Regulator AraC Family BZ23_1733 ENOG4105M9B inner membrane protein ydgK BZ23_1736 ENOG4108JJA ABC, transporter BZ23_1740 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator BZ23_1742 ENOG4105CNN ABC, transporter BZ23_1744 ENOG4105D9R oxidoreductase BZ23_1745 ENOG4105DHU Bile acid BZ23_1749 ENOG4105CI1 PTS System BZ23_175 ENOG4105M6F mutator MutT protein BZ23_1750 ENOG4105FDP GntR family transcriptional regulator BZ23_1751 ENOG4106J39 exported protein BZ23_1752 ENOG4105EIP mannose-6-phosphate isomerase BZ23_1753 ENOG4105C9Q fumarate hydratase class II BZ23_1755 ENOG4105D94 Major Facilitator Superfamily BZ23_1756 ENOG4106NZI LysR family Transcriptional regulator BZ23_1757 ENOG4105DAG ROK family BZ23_1759 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ23_1761 ENOG4105KBG Protein of unknown function (DUF1161) BZ23_1763 ENOG4105EMU Dehydrogenase BZ23_1764 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BZ23_1765 ENOG4105C26 Dehydrogenase BZ23_1767 ENOG4105DWP Membrane BZ23_1768 ENOG4105C87 Aminotransferase class I and II BZ23_1769 ENOG4105DFD Na H antiporter BZ23_1770 ENOG41060NJ transcriptional regulator BZ23_1772 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ23_1773 ENOG4105CNN ABC, transporter BZ23_1774 ENOG4105C2J ABC transporter BZ23_1776 ENOG4107UWC ABC, transporter BZ23_1777 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ23_1779 ENOG4105FYV Amp nucleosidase BZ23_1784 ENOG4105C7K acetolactate synthase BZ23_1785 ENOG4105M71 acetolactate synthase 1 regulatory subunit BZ23_1786 ENOG4105PAD Hydrolase BZ23_1789 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ23_179 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BZ23_1790 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BZ23_1791 ENOG4105Q9Y Universal stress protein BZ23_1792 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ23_1793 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ23_1794 ENOG4105C5D exported protein BZ23_1795 ENOG4105D5Q Arginine ornithine antiporter BZ23_1797 ENOG4107EXC regulatoR BZ23_1798 ENOG4105JJR Histidine kinase BZ23_1799 ENOG4105CTD carboxy-peptidase BZ23_1801 ENOG4108RS6 transposase BZ23_1803 ENOG4105DS1 cytochrome b561 BZ23_1805 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap BZ23_1808 ENOG4105CQ7 ATP-dependent helicase BZ23_1810 ENOG4105DKT Transcriptional regulator BZ23_1811 ENOG4105DEI Mannitol dehydrogenase BZ23_1812 ENOG4105WXT Conserved Protein BZ23_1813 ENOG410689M (LipO)protein BZ23_1814 ENOG4107H52 Dicarboxylate transport BZ23_1815 ENOG4105C5I Dehydrogenase BZ23_1816 ENOG41090X5 Heat shock protein hslJ BZ23_1818 ENOG4105KT7 mgtC SapB transporter BZ23_182 ENOG4105D7Q type ii secretion system BZ23_1820 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) BZ23_1826 ENOG4107QSI ABC, transporter BZ23_1827 ENOG4105KXI murein peptide amidase A BZ23_1828 ENOG4107S8C mandelate racemase muconate lactonizing BZ23_1829 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BZ23_183 ENOG4107QHF type ii secretion system protein e BZ23_1830 ENOG4108RS6 transposase BZ23_1835 ENOG4105CM6 amino acid regulated cytosolic protein BZ23_1837 ENOG4105FM1 phage shock protein C BZ23_1838 ENOG4105YYT phage shock protein B BZ23_1839 ENOG41087YS Phage shock protein A BZ23_184 ENOG4108ZUW Major pilin subunit BZ23_1840 ENOG4105E51 psp operon transcriptional activator BZ23_1841 ENOG4108HIY periplasmic BZ23_1842 ENOG4108I5W peptide transport system, permease protein BZ23_1843 ENOG4108EU3 peptide transport system, permease BZ23_1844 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein BZ23_1845 ENOG4108JQ2 peptide transport system atp-binding protein BZ23_1846 ENOG4105Q4T oxidoreductase BZ23_1847 ENOG4105DUX Transporter BZ23_1848 ENOG41069YE inner membrane protein yohC BZ23_1849 ENOG4108ZR5 Conserved Protein BZ23_185 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BZ23_1850 ENOG4108K3A Glutathione S-transferase BZ23_1854 ENOG410642K Lysozyme inhibitor BZ23_1856 ENOG4108XTF Outer Membrane Lipoprotein BZ23_1858 ENOG4107RGM aldo keto reductase BZ23_1859 ENOG4105XZD Fe-S protein BZ23_186 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ23_1860 ENOG4105DIJ Phosphoethanolamine transferase BZ23_1861 ENOG4108WUH Transcriptional regulator, TetR family BZ23_1862 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ23_1864 ENOG4108UYE Lactoylglutathione lyase BZ23_1866 ENOG4105M2J Glutaredoxin BZ23_1868 ENOG4105K4H Nlp p60 protein BZ23_1869 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ23_187 ENOG4106A72 regulatory protein AmpE BZ23_1872 ENOG4105F52 Transcriptional regulator BZ23_1873 ENOG4105CZQ inner membrane transport protein YdhC BZ23_1874 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BZ23_1875 ENOG4108R6K riboflavin synthase, subunit alpha BZ23_188 ENOG4105C85 amino acid BZ23_1880 ENOG4105CA9 Pyruvate kinase BZ23_1881 ENOG4105KMX major outer membrane lipoprotein BZ23_1882 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BZ23_1885 ENOG4105JRK feS assembly protein SufD BZ23_1886 ENOG4105C3K feS assembly ATPase SufC BZ23_1887 ENOG4105DIW FeS assembly protein SUFB BZ23_1888 ENOG4108Z4V iron-sulfur cluster assembly BZ23_1889 ENOG4105KA0 thioesterase Superfamily protein BZ23_189 ENOG41073TP transcriptional regulator BZ23_1890 ENOG4105CQB FAD linked oxidase domain protein BZ23_1891 ENOG4105IPI Membrane BZ23_1892 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BZ23_1894 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ23_1897 ENOG4108QBX (LipO)protein BZ23_19 ENOG4108M3P Membrane BZ23_190 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BZ23_1905 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) BZ23_1906 ENOG4108V06 Glutathione peroxidase BZ23_1909 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BZ23_191 ENOG4107QSN dihydrolipoamide acetyltransferase BZ23_1916 ENOG41087WU BZ23_192 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ23_1920 ENOG4105DSE periplasmic solute binding protein BZ23_1921 ENOG4105DIK (ABC) transporter BZ23_1922 ENOG4105CC5 ABC transporter BZ23_1923 ENOG4105CC5 ABC transporter BZ23_1924 ENOG4105FGM Fructosamine kinase BZ23_1925 ENOG4107PN8 YfeABCD locus regulator BZ23_1926 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 BZ23_1927 ENOG4105M5J Cupin 2, conserved barrel domain protein BZ23_1929 ENOG4105CHR reductase BZ23_193 ENOG4107QIJ Aconitate hydratase 2 BZ23_1930 ENOG41061NF Pectate lyase BZ23_1931 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BZ23_1932 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BZ23_1934 ENOG4105WEM extracellular solute-binding protein BZ23_1935 ENOG4108PU9 oligogalacturonate-specific porin BZ23_1936 ENOG4107K5X Membrane-bound metal-dependent hydrolase BZ23_1937 ENOG4108ETY sodium dicarboxylate symporter BZ23_1938 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ23_1940 ENOG4105CAZ oligogalacturonide lyase BZ23_1941 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ23_1942 ENOG4108VEV chaperone BZ23_1945 ENOG4108VEV chaperone BZ23_1946 ENOG4105H8W Fimbrial protein BZ23_1949 ENOG4105CN1 protease BZ23_195 ENOG4105RPH Inner membrane protein YddG BZ23_1951 ENOG4108ZGC gaf domain protein BZ23_1952 ENOG4105H2K paraquat-inducible protein a BZ23_1953 ENOG4105DY2 Paraquat-inducible protein b BZ23_1957 ENOG4105GQR Chaperone BZ23_1960 ENOG4105WT8 Protein of unknown function (DUF1480) BZ23_1967 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ23_1971 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ23_1972 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) BZ23_1973 ENOG4108VYJ response regulator receiver protein BZ23_1975 ENOG4105BZU Histidine kinase BZ23_1976 ENOG4105C8Q Methyl-accepting chemotaxis BZ23_1977 ENOG4105C8Q Methyl-accepting chemotaxis BZ23_198 ENOG4108ZRK uncharacterized protein yacC BZ23_1980 ENOG4108V3W Chemotaxis protein, CheW BZ23_1981 ENOG4105CBS Chea signal transduction histidine kinase BZ23_1982 ENOG4105ER2 Ompa motb domain protein BZ23_1983 ENOG4107RD7 Flagellar Motor Protein, MotA BZ23_1984 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region BZ23_1986 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BZ23_1987 ENOG4105KT7 mgtC SapB transporter BZ23_1988 ENOG4105C8Q Methyl-accepting chemotaxis BZ23_199 ENOG4105E3B Multicopper oxidase BZ23_1990 ENOG4105VEQ Cold shock protein BZ23_1994 ENOG4105GSJ Inner membrane protein ylaC BZ23_1995 ENOG4108XM1 transcriptional regulator AsnC family BZ23_1997 ENOG41061EV selenium-binding protein YdfZ BZ23_1998 ENOG4105D6F Phosphatase BZ23_200 ENOG4108UGV hypoxanthine phosphoribosyltransferase BZ23_2000 ENOG4105KVH Transcriptional regulator BZ23_2001 ENOG4105ECR NmrA family BZ23_2002 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BZ23_2004 ENOG4106NDP Transcriptional regulator BZ23_2005 ENOG4108HMX isocitrate dehydrogenase (NADP) BZ23_2006 ENOG4108R99 pseudouridine synthase BZ23_201 ENOG41077A9 carbonic anhydrase BZ23_2010 ENOG4107QTF adenylosuccinate lyase BZ23_2012 ENOG4105XJC Two component transcriptional regulator (Winged helix family BZ23_2014 ENOG4105EZE Cupin 4 family protein BZ23_2016 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BZ23_2018 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ23_202 ENOG4105DA5 (ABC) transporter BZ23_2020 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ23_2021 ENOG4108JA2 transcriptioN-repair coupling factor BZ23_2022 ENOG4107MBR 17 kDa surface antigen BZ23_2025 ENOG4105CEP NADH dehydrogenase BZ23_203 ENOG4105E3A (ABC) transporter BZ23_2030 ENOG41090DQ Lipoprotein BZ23_2031 ENOG4105K59 histidine triad (HIT) protein BZ23_2032 ENOG4105F9E Shikimate 5-dehydrogenase BZ23_2039 ENOG4105ED4 portal protein BZ23_204 ENOG4107BJW polysaccharide deacetylase BZ23_2043 ENOG4105CI1 PTS System BZ23_2044 ENOG4105F8V Hydrolase, tatD family BZ23_2045 ENOG4107QRG dna polymerase iii BZ23_2047 ENOG4105HHA aminodeoxychorismate lyase BZ23_2048 ENOG4105YAZ 4-amino-4-deoxychorismate lyase BZ23_2049 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ23_2051 ENOG4105CHR reductase BZ23_2052 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ23_2055 ENOG4105VGS 50s ribosomal protein l32 BZ23_2056 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BZ23_2058 ENOG4105EI2 Pseudouridine synthase BZ23_2060 ENOG4107QQB Ribonuclease E BZ23_2061 ENOG41067V3 Antibiotic biosynthesis monooxygenase BZ23_2064 ENOG4105PVA Biofilm formation regulatory protein BssS BZ23_2067 ENOG4105DSF transport protein BZ23_2070 ENOG4105D1S lipid A biosynthesis BZ23_2071 ENOG4105DUX Transporter BZ23_2072 ENOG4105NAC (LipO)protein BZ23_2073 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) BZ23_2074 ENOG4105DJ9 glucan biosynthesis protein BZ23_2075 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) BZ23_2079 ENOG4105VJY transcriptional regulator BZ23_208 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BZ23_2080 ENOG4107YC3 synthase BZ23_2081 ENOG4105ETT transcriptional Regulator, LysR family BZ23_2083 ENOG4105C54 Major Facilitator superfamily BZ23_2085 ENOG4105CPC Aldo Keto reductase BZ23_2086 ENOG4108Y1S CRISPR-associated protein, Csy4 family BZ23_2087 ENOG4105M6W Crispr-associated protein, Csy3 family BZ23_2088 ENOG4105DZX CRISPR-associated protein, Csy2 family BZ23_2089 ENOG4105ENG CRISPR-associated protein, Csy1 family BZ23_209 ENOG4105DJ0 Poly(A) Polymerase BZ23_2090 ENOG4107IIZ CRISPR-associated helicase, Cas3 BZ23_2091 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) BZ23_2092 ENOG4105CUY Mechanosensitive ion channel BZ23_2096 ENOG4105HY2 Glycosidase related protein BZ23_2097 ENOG4105DRS transport system, permease BZ23_21 ENOG4108XCZ PTS System BZ23_2100 ENOG4105ETE Transcriptional regulator (LacI family BZ23_2102 ENOG4108IJ9 (ABC) transporter BZ23_2105 ENOG4105CKT filamentous hemagglutinin BZ23_2108 ENOG4105CKT filamentous hemagglutinin BZ23_2109 ENOG4105D5K Hemolysin activator protein BZ23_211 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BZ23_2110 ENOG4105E3J oxidoreductase BZ23_2111 ENOG4105DVW rieske (2Fe-2S) BZ23_2112 ENOG4105C94 Transporter BZ23_2113 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BZ23_2114 ENOG4105EJC lysr family transcriptional regulator BZ23_2115 ENOG4105FKQ transcriptional regulator BZ23_2116 ENOG4105CNN ABC, transporter BZ23_2117 ENOG4105C2J ABC transporter BZ23_2118 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ23_2119 ENOG4105CPQ Dehydrogenase BZ23_2123 ENOG4108T1M outer membrane protein x BZ23_2129 ENOG4107R0W ABC transporter BZ23_213 ENOG4107XID 2'-5' rna ligase BZ23_2130 ENOG4105E5Q amino acid AbC transporter BZ23_2131 ENOG4105CDA abc transporter atp-binding protein BZ23_2132 ENOG4107SDU Methyl-accepting chemotaxis BZ23_2134 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction BZ23_2135 ENOG4108MTB glycosyl transferase family BZ23_2136 ENOG4105CEY Amp-dependent synthetase and ligase BZ23_2138 ENOG4108IPT Naphthoate synthase BZ23_214 ENOG4105CQ7 ATP-dependent helicase BZ23_2141 ENOG4105E4F Isochorismate synthase BZ23_2143 ENOG4105TNS Conserved Protein BZ23_2145 ENOG4105C01 Dihydroxy-acid dehydratase BZ23_2148 ENOG4105C5I Dehydrogenase BZ23_2149 ENOG4105K2J Transcriptional regulator BZ23_215 ENOG4105BZ4 penicillin-binding protein BZ23_2150 ENOG4105F32 YngK protein BZ23_2151 ENOG4105CHR reductase BZ23_2152 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ23_2153 ENOG4108R66 Conserved Protein BZ23_2156 ENOG4105C8S subunit m BZ23_2157 ENOG4105D65 subunit l BZ23_2159 ENOG4107UFS subunit j BZ23_216 ENOG4105E0A ABC, transporter BZ23_2162 ENOG4108IEH NADH dehydrogenase subunit g BZ23_2163 ENOG4107QIZ NADH dehydrogenase BZ23_2164 ENOG4105GKE subunit e BZ23_2166 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BZ23_2168 ENOG4107NQ8 LysR family Transcriptional regulator BZ23_2169 ENOG4105CHM Aminotransferase BZ23_217 ENOG4105J76 Periplasmic binding protein BZ23_2172 ENOG4107QWE )-transporter BZ23_2173 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 BZ23_2177 ENOG4105C6K Malic enzyme BZ23_2178 ENOG4107P2S Transcriptional regulator BZ23_218 ENOG4105S6R Iron-hydroxamate transporter permease subunit BZ23_2181 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BZ23_2182 ENOG4105PTV Nudix Hydrolase BZ23_2183 ENOG4108RE9 Phosphodiesterase BZ23_2186 ENOG4105ECP epimerase BZ23_2187 ENOG4108JEH abc transporter atp-binding protein BZ23_2188 ENOG4106YG3 ABC transporter BZ23_2189 ENOG4105DSP amino acid AbC transporter BZ23_2190 ENOG4105E89 ABC transporter BZ23_2191 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BZ23_2192 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BZ23_2193 ENOG4105E96 Colicin v production protein BZ23_2194 ENOG4108S3P Sporulation domain protein BZ23_2195 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BZ23_2197 ENOG4105DQR SNARE associated Golgi BZ23_2199 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ23_22 ENOG4106R3P AraC family transcriptional regulator BZ23_2202 ENOG410631K Membrane BZ23_2203 ENOG4106WZ1 flagella biosynthesis regulator BZ23_2206 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ23_2208 ENOG4105MH2 YfcL protein BZ23_2209 ENOG4108BPE -transporting atpase BZ23_2210 ENOG4105EJ9 Membrane BZ23_2213 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BZ23_2215 ENOG4108BY2 phosphohistidine phosphatase BZ23_2218 ENOG4105KZW UPF0381 protein BZ23_2219 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BZ23_222 ENOG4105EN6 Membrane BZ23_2220 ENOG410903C (LipO)protein BZ23_2221 ENOG4105KWW Biogenesis protein BZ23_2222 ENOG4105KWW Biogenesis protein BZ23_2223 ENOG4107QX9 Thiol disulfide interChange protein BZ23_2224 ENOG4105DA4 cytochrome c-type biogenesis protein BZ23_2226 ENOG4105X3C heme exporter protein BZ23_2227 ENOG41060IM Heme exporter protein BZ23_2228 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BZ23_2232 ENOG4108V0P LemA family BZ23_2234 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BZ23_2240 ENOG4105CS6 Rhs element vgr protein BZ23_2249 ENOG4105CW0 outer membrane usher protein BZ23_2250 ENOG4105GQR Chaperone BZ23_2252 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ23_226 ENOG4105C0H protease BZ23_2262 ENOG4105CVE Lytic murein transglycosylase BZ23_2268 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ23_227 ENOG4105BZU Histidine kinase BZ23_2270 ENOG4107QY8 reductase BZ23_2271 ENOG4105QAX Iron-sulfur BZ23_2272 ENOG4107KGK dmso reductase anchor subunit BZ23_2273 ENOG4108NEM leader-binding protein dmsD BZ23_2275 ENOG4107Y60 (LipO)protein BZ23_2277 ENOG4106B0W Curli production assembly transport component CsgG BZ23_2279 ENOG4108VKM cytochrome b561 BZ23_228 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ23_2280 ENOG4105CHM Aminotransferase BZ23_2281 ENOG41072TH Protein of unknown function (DUF1479) BZ23_2284 ENOG4105C5Q Transcriptional regulator BZ23_2285 ENOG4105CPC Aldo Keto reductase BZ23_2288 ENOG4105D9N nucleoside BZ23_229 ENOG4105DXN mazG family BZ23_2299 ENOG4105VRT cytoplasmic protein BZ23_23 ENOG4108YRF PTS System BZ23_2302 ENOG4105EXN Sulfate transport protein CysZ BZ23_2303 ENOG4105C6T cysteine synthase BZ23_2304 ENOG4105KZ7 phosphocarrier protein hpr BZ23_2306 ENOG4105C5Y PTS System BZ23_2307 ENOG4105E0F Histidine kinase BZ23_2308 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ23_2309 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ23_2312 ENOG4105E1V na solute symporter BZ23_2314 ENOG4107RAQ aminopeptidase BZ23_2315 ENOG4105C87 Aminotransferase class I and II BZ23_2317 ENOG41062D9 Histidine kinase BZ23_2318 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ23_2320 ENOG4105C6T cysteine synthase BZ23_2322 ENOG4105ECW sulfate abc transporter BZ23_2323 ENOG4108I5D sulfate abc transporter BZ23_2324 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein BZ23_2326 ENOG4105QEK Transcriptional regulator BZ23_2327 ENOG4108R66 Conserved Protein BZ23_233 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BZ23_2332 ENOG4105EZR dyp-type peroxidase family protein BZ23_2333 ENOG4105E7K (LipO)protein BZ23_2334 ENOG4105H4F exported protein BZ23_234 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BZ23_2344 ENOG4105C6K Malic enzyme BZ23_2346 ENOG4105CUW cytochrome C-TYPE protein BZ23_2347 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) BZ23_2349 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase BZ23_2350 ENOG4108ZNS ferredoxin-type protein NapF BZ23_2351 ENOG4105WH1 Two component transcriptional regulator luxr family BZ23_2353 ENOG4105BZS acriflavin resistance protein BZ23_2355 ENOG4105S2T inner membrane protein YbcI BZ23_2356 ENOG4105C4X radical SAM domain protein BZ23_2357 ENOG4105ENH Sulfatase BZ23_2358 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ23_2359 ENOG4107Z33 ABC transporter, permease BZ23_2360 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC BZ23_2362 ENOG4105KUZ arsenate reductase BZ23_2368 ENOG4105CGZ zinc metallopeptidase BZ23_2370 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ23_2372 ENOG4105RH4 Glycine cleavage system transcriptional repressor BZ23_2373 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BZ23_2376 ENOG4105C02 permease BZ23_2377 ENOG4105ERG peptidase m48, ste24p BZ23_2378 ENOG4105K89 arsenate reductase BZ23_2380 ENOG4105C2W permease BZ23_2383 ENOG4108V3E phosphoribosylglycinamide formyltransferase BZ23_2384 ENOG4108MK9 spermidine N(1)-acetyltransferase BZ23_2385 ENOG4108C80 FliB family BZ23_2387 ENOG4105E2Z phosphate ABC transporter (Permease BZ23_2388 ENOG4105C8U phosphate abc transporter BZ23_2389 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BZ23_2390 ENOG4105C9X ppx gppa phosphatase BZ23_2391 ENOG4105CJW magnesium transporter BZ23_2392 ENOG4105R8A Heat shock protein BZ23_2394 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BZ23_2395 ENOG4105F38 ABC transporter, permease BZ23_2397 ENOG4108JPW Aminotransferase BZ23_2399 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ23_24 ENOG4105DM4 PTS System BZ23_2404 ENOG4105EB3 Histidine kinase BZ23_2405 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ23_2406 ENOG4105KWI UPF0339 protein BZ23_2407 ENOG4105CFP Peptidase U32 BZ23_2409 ENOG4108ZGU inhibitor of vertebrate lysozyme BZ23_2411 ENOG4105DWF phosphomethylpyrimidine kinase BZ23_2417 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ23_2419 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BZ23_2421 ENOG4105VPD cellular component movement BZ23_2424 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ23_2425 ENOG4105N21 Membrane BZ23_243 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BZ23_2433 ENOG4108MGN ATP-binding component of a transport system BZ23_2434 ENOG4108MGN ATP-binding component of a transport system BZ23_2435 ENOG4105YYA enhanced serine sensitivity protein SseB BZ23_2437 ENOG4105WVQ Fe-S assembly protein IscX BZ23_2438 ENOG4108ZIT Ferredoxin, 2FE-2S BZ23_244 ENOG4105N0Z inner membrane protein ygbE BZ23_2442 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BZ23_2443 ENOG4105C3J Cysteine desulfurase BZ23_2447 ENOG4105D7X high-affinity nickel-transporter BZ23_2448 ENOG41065CD Exported protein BZ23_2449 ENOG4105D8G Major Facilitator superfamily BZ23_2450 ENOG4108MN2 Stationary phase inducible protein CsiE BZ23_2453 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ23_2454 ENOG4108M21 BZ23_2455 ENOG4108YZA Nitrogen regulatory protein pii BZ23_2456 ENOG4105C4K Nad synthetase BZ23_2457 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ23_2458 ENOG4108SKK alpha helix protein BZ23_2459 ENOG4107WP9 Histidine kinase BZ23_2464 ENOG4108Z6B deaminase BZ23_2465 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB BZ23_2467 ENOG4106G6Q Transcriptional regulator BZ23_2468 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BZ23_2474 ENOG4105C3F Signal peptidase i BZ23_2477 ENOG4105WMJ Positive regulator of sigma E, RseC MucC BZ23_2478 ENOG4105VQK sigma E regulatory protein, MucB RseB BZ23_2479 ENOG41069PW sigma-e factor negative regulatory protein BZ23_2481 ENOG4108IYU L-aspartate oxidase BZ23_2483 ENOG4105C1J atp-dependent rna helicase BZ23_2494 ENOG4107R7A Allophanate hydrolase subunit 2 BZ23_2495 ENOG4105P4J Allophanate hydrolase, subunit 1 BZ23_2497 ENOG4107QNR UPF0135 protein BZ23_2498 ENOG4107RF4 Phosphodiesterase BZ23_2499 ENOG4105CVP deoxyribo-dipyrimidine photolyase BZ23_25 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BZ23_2500 ENOG4107SEY Conserved Protein BZ23_2501 ENOG4105XIQ Protein of unknown function (DUF2517) BZ23_2505 ENOG4105C08 Histidine kinase BZ23_2506 ENOG4105EEX Two component transcriptional regulator (Winged helix family BZ23_2508 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 BZ23_251 ENOG4108K5P (LipO)protein BZ23_2513 ENOG4105EZV Transcriptional regulator BZ23_2514 ENOG4105VCP PTS System BZ23_2515 ENOG4105CK1 PTS System BZ23_2516 ENOG4105VZJ PTS System BZ23_2518 ENOG41086WQ Protein CrcB homolog BZ23_2519 ENOG4107SVH Potassium channel protein BZ23_252 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ23_2520 ENOG4105XXV Acid-resistance protein BZ23_2524 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) BZ23_2531 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) BZ23_2532 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) BZ23_2533 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ23_2534 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ23_2535 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BZ23_2536 ENOG4105VEQ Cold shock protein BZ23_2538 ENOG4108SAJ Protein of unknown function (DUF1198) BZ23_2539 ENOG4108WMJ Protein of unknown function (DUF2002) BZ23_254 ENOG4108YZG isomerase BZ23_2544 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ23_2545 ENOG4108IJ7 Glycine betaine BZ23_2546 ENOG4108HQS Glycine betaine BZ23_2547 ENOG4105GIJ Glycine betaine BZ23_2549 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BZ23_255 ENOG4105CPQ Dehydrogenase BZ23_2551 ENOG4108JDX DNA polymerase iii, epsilon subunit BZ23_2553 ENOG4105D1A Methyltransferase BZ23_2555 ENOG4105E9H Lytic Murein transglycosylase BZ23_2558 ENOG4105CV8 reductase BZ23_256 ENOG4105CHR reductase BZ23_2565 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BZ23_2567 ENOG4108UMI ABC transporter, permease BZ23_2568 ENOG4105D01 (LipO)protein BZ23_2569 ENOG4108R8X outer membrane lipoprotein BZ23_257 ENOG4105CMT Dihydroxyacetone kinase BZ23_2570 ENOG4108R96 Methyltransferase, YaeB family BZ23_2572 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BZ23_2573 ENOG4108YZN class I peptide chain release factor BZ23_2574 ENOG4108VWS Yaeq family BZ23_2576 ENOG4105M1T rho-binding antiterminator BZ23_2579 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BZ23_2581 ENOG4105C0B DNA polymerase III (alpha subunit) BZ23_2583 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BZ23_2587 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) BZ23_2589 ENOG4105DZP Membrane-associated zinc metalloprotease BZ23_259 ENOG4105DKT Transcriptional regulator BZ23_2590 ENOG4105KNE Phosphatidate cytidylyltransferase BZ23_2591 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BZ23_2592 ENOG4108RS6 transposase BZ23_2598 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ23_26 ENOG4105RI1 glycoprotein receptor BZ23_2602 ENOG4105QDK Flavodoxin BZ23_2603 ENOG4105DR9 pseudouridine synthase BZ23_2604 ENOG4105WP7 tRNA pseudouridine synthase C BZ23_2607 ENOG4105EWT decarboxylase family BZ23_2610 ENOG4105M08 Membrane BZ23_2611 ENOG4105ETT transcriptional Regulator, LysR family BZ23_2612 ENOG4105C9B Cysteine desulfurase BZ23_2613 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BZ23_2614 ENOG4105CUZ uba thif-type nad fad binding protein BZ23_2615 ENOG4105CA3 membrane-bound lytic murein transglycosylase BZ23_2619 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ23_2621 ENOG4107QYX exodeoxyribonuclease v alpha BZ23_2622 ENOG4107QKA exodeoxyribonuclease V beta BZ23_2623 ENOG4107QXK peptidase BZ23_2624 ENOG4105DSY exodeoxyribonuclease V, gamma BZ23_2632 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BZ23_2635 ENOG4105CPC Aldo Keto reductase BZ23_264 ENOG4105E89 ABC transporter BZ23_2641 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BZ23_2642 ENOG41060NJ transcriptional regulator BZ23_2643 ENOG4105F27 Major Facilitator BZ23_2644 ENOG4105RQF LysR family Transcriptional regulator BZ23_2645 ENOG4105EJC lysr family transcriptional regulator BZ23_2647 ENOG4105C8Q Methyl-accepting chemotaxis BZ23_265 ENOG4105CA0 peroxidase BZ23_2660 ENOG4105D7Q type ii secretion system BZ23_2661 ENOG4107QHF type ii secretion system protein e BZ23_2665 ENOG4107B2H carbonic anhydrase BZ23_267 ENOG4105D05 Receptor BZ23_2670 ENOG4105CBG Sulfatase BZ23_2671 ENOG4105E98 transcriptional regulator DeoR family BZ23_2672 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of BZ23_2673 ENOG4105E70 isomerase BZ23_2674 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB BZ23_2675 ENOG4105ETZ PTS System BZ23_2676 ENOG4105F3R pts system mannose fructose sorbose family iid BZ23_2677 ENOG4108YTN IIa component BZ23_2678 ENOG4105CE4 GlcNAc 6-P deacetylase BZ23_2679 ENOG4105CHR reductase BZ23_2681 ENOG4105C4X radical SAM domain protein BZ23_2682 ENOG4105ENH Sulfatase BZ23_2684 ENOG4105D2N Aldolase BZ23_2687 ENOG4105ETE Transcriptional regulator (LacI family BZ23_2688 ENOG4105DPW Major facilitator superfamily MFS_1 BZ23_269 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ23_2690 ENOG4105ETE Transcriptional regulator (LacI family BZ23_2692 ENOG4105CI1 PTS System BZ23_2693 ENOG4105C4C beta-galactosidase BZ23_2695 ENOG4105EG2 ABC transporter, permease BZ23_2697 ENOG4107FKK extracellular solute-binding protein family 1 BZ23_2700 ENOG4105CNN ABC, transporter BZ23_2701 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ23_2703 ENOG4108UY0 (LipO)protein BZ23_2704 ENOG4105NTW Transcriptional regulator BZ23_271 ENOG4107GFK fumarate BZ23_272 ENOG4105CMG Carbohydrate kinase BZ23_2721 ENOG4105WJ3 XRE family Transcriptional regulator BZ23_2722 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation BZ23_2726 ENOG4105DFP Integrase BZ23_273 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase BZ23_2730 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BZ23_2731 ENOG4105T95 Thiol disulfide interChange protein BZ23_2732 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ23_2733 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) BZ23_2734 ENOG4105CT7 inner membrane cred family protein BZ23_2735 ENOG4105EB3 Histidine kinase BZ23_2736 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ23_2737 ENOG4105Y75 tpr repeat protein BZ23_274 ENOG4105F5R ABC transporter BZ23_2740 ENOG4108UT2 hemolysin iii BZ23_2747 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ23_2748 ENOG4105D0A hydroxylase BZ23_2749 ENOG4107RAQ aminopeptidase BZ23_275 ENOG4105CNN ABC, transporter BZ23_2752 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BZ23_2753 ENOG4108JQ1 Dehydrogenase BZ23_2754 ENOG4105E66 phosphoriboisomerase A BZ23_2756 ENOG4105MPN Membrane BZ23_2758 ENOG4105D64 Mechanosensitive ion channel BZ23_2759 ENOG4105D2N Aldolase BZ23_276 ENOG4105C2J ABC transporter BZ23_2762 ENOG4105CV1 Transketolase (EC 2.2.1.1) BZ23_2763 ENOG4108K0D peptidase, M48 BZ23_2764 ENOG4108RS6 transposase BZ23_2766 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BZ23_2770 ENOG4105RWS endonuclease I BZ23_2771 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BZ23_2772 ENOG4105D7Z glutathione synthase BZ23_2775 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) BZ23_2777 ENOG4105CZX twitching motility protein BZ23_2778 ENOG4105DFA alanine racemase domain protein BZ23_2779 ENOG4105II7 pyrroline-5-carboxylate reductase BZ23_278 ENOG4105E98 transcriptional regulator DeoR family BZ23_2780 ENOG4108VIA integral membrane protein BZ23_2782 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BZ23_2783 ENOG4105CSA Coproporphyrinogen iii oxidase BZ23_2784 ENOG4105EUK rtx toxin RtxA BZ23_2785 ENOG4105K33 Periplasmic Protein BZ23_2786 ENOG4105CSV Glutaminase BZ23_2787 ENOG41090ED Protein with unknown function (DUF469) BZ23_2789 ENOG4105CEN a g-specific adenine glycosylase BZ23_279 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ23_2794 ENOG4105CNN ABC, transporter BZ23_2795 ENOG4105C2J ABC transporter BZ23_2796 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ23_2797 ENOG4105CXN decarboxylase BZ23_280 ENOG4107QY8 reductase BZ23_2806 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ23_2807 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ23_2809 ENOG4105CDV Ompa motb domain protein BZ23_281 ENOG4105QAX Iron-sulfur BZ23_282 ENOG4107KGK dmso reductase anchor subunit BZ23_2826 ENOG4105DUU IucA IucC family protein BZ23_2827 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ23_2829 ENOG4105CT4 transporter BZ23_283 ENOG4108NEM leader-binding protein dmsD BZ23_2831 ENOG4105ETE Transcriptional regulator (LacI family BZ23_2832 ENOG4105C8P )-transporter BZ23_2833 ENOG41062WK cellular response to acidity BZ23_2838 ENOG4105CNA YD repeat protein BZ23_284 ENOG4105CPW cytochrome b561 BZ23_2840 ENOG4105CNA YD repeat protein BZ23_2845 ENOG4105CNA YD repeat protein BZ23_2847 ENOG4105CS6 Rhs element vgr protein BZ23_285 ENOG4108XVM Cytochrome b(562) BZ23_2850 ENOG4107EFN gluconate transport system permease 3 BZ23_2854 ENOG4105BZ1 (ABC) transporter BZ23_2860 ENOG4105C0W non-ribosomal peptide synthetase BZ23_2861 ENOG4105C0W non-ribosomal peptide synthetase BZ23_2862 ENOG4107ZSV Receptor BZ23_2863 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BZ23_2864 ENOG4105CFC Transporter BZ23_2865 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway BZ23_2866 ENOG4108RS6 transposase BZ23_2874 ENOG4105BZU Histidine kinase BZ23_2876 ENOG4105DQ6 Transposase BZ23_2877 ENOG4108XTF Outer Membrane Lipoprotein BZ23_2882 ENOG4107RD7 Flagellar Motor Protein, MotA BZ23_2888 ENOG410804A Flagellar hook-associated 2 domain-containing protein BZ23_2889 ENOG4105I03 Flagellin BZ23_289 ENOG4105C2J ABC transporter BZ23_2892 ENOG4105I03 Flagellin BZ23_2893 ENOG4108M3R transcriptional activator CadC BZ23_2897 ENOG4105E1Q flagellar hook-associated protein BZ23_2899 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BZ23_290 ENOG4105CNN ABC, transporter BZ23_2900 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BZ23_2901 ENOG4105CGA flagellar basal-body rod protein FlgG BZ23_2902 ENOG4108KPB Flagellar basal-body rod protein FlgF BZ23_2903 ENOG4105BZE flagellar hook protein, FlgE BZ23_2904 ENOG4105W00 Flagellar hook capping protein BZ23_2905 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ23_2906 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ23_2907 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA BZ23_291 ENOG4108HHA Transketolase BZ23_2911 ENOG4108JIR Flagellum-specific ATP synthase BZ23_2914 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ23_2916 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ23_2918 ENOG4105DD5 Flagellar motor switch protein BZ23_2919 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ23_292 ENOG4108IUS Transketolase BZ23_2920 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ23_2921 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ23_2922 ENOG4105D00 flagellar biosynthetic protein flhB BZ23_2926 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein BZ23_2928 ENOG4106P2F Pfam:Pili_assembly_C BZ23_2929 ENOG4106PG1 outer membrane usher protein BZ23_293 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BZ23_2931 ENOG4105E03 chitinase BZ23_2933 ENOG4108M1A Chitin-binding protein BZ23_2950 ENOG4108ZZF transport protein (ExbD) BZ23_2952 ENOG4105CWK Biopolymer transport protein, ExbB BZ23_2953 ENOG4105C28 cystathionine BZ23_2954 ENOG4108K81 inner membrane protein YghB BZ23_2955 ENOG4105CF7 AraC family transcriptional regulator BZ23_2956 ENOG4108I6A alcohol dehydrogenase BZ23_2957 ENOG4105CV8 reductase BZ23_2959 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) BZ23_2960 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase BZ23_2961 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ23_2962 ENOG4105NF4 modulator of drug activity BZ23_2963 ENOG4105CR8 Transcriptional regulator BZ23_2964 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ23_2965 ENOG4105IPS esterase BZ23_2967 ENOG4105DQ6 Transposase BZ23_2968 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BZ23_2969 ENOG4108SX3 cytoplasmic protein BZ23_2970 ENOG41087AY ADP-Ribose pyrophosphatase BZ23_2971 ENOG4105DFG type I secretion outer membrane protein BZ23_2974 ENOG4106032 Glutathionylspermidine synthase BZ23_2975 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BZ23_2977 ENOG4105W0Z cytoplasmic protein BZ23_2978 ENOG4105DVH amino acid BZ23_2981 ENOG4105I7R Adenylate cyclase BZ23_2982 ENOG4106MWK domain protein BZ23_2985 ENOG4107ZVW dihydroneopterin aldolase BZ23_2988 ENOG4105VCC 30S ribosomal protein S21 BZ23_2989 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BZ23_2990 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ23_3 ENOG4105XEP YhcH YjgK YiaL family protein BZ23_300 ENOG4105D5G Transposase BZ23_3010 ENOG4106YSC BZ23_3028 ENOG4105KME endoribonuclease L-psp BZ23_3032 ENOG4105CHM Aminotransferase BZ23_3035 ENOG4105J12 Multidrug resistance protein mdtN BZ23_3036 ENOG4108MI0 Resistance protein BZ23_3038 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ23_304 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BZ23_3040 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BZ23_3042 ENOG4108IJG ABC transporter substrate-binding protein BZ23_3043 ENOG4107KJX Transcriptional regulator BZ23_3044 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 BZ23_3049 ENOG4105CKT filamentous hemagglutinin BZ23_3056 ENOG4105CKT filamentous hemagglutinin BZ23_3057 ENOG4105D5K Hemolysin activator protein BZ23_3058 ENOG4108M24 von Willebrand factor, type A BZ23_3061 ENOG4108M24 von Willebrand factor, type A BZ23_3064 ENOG4108YK4 Acid-resistance membrane protein BZ23_3065 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ23_3068 ENOG4108VKG metal-dependent hydrolase BZ23_3069 ENOG4105EE0 oxidoreductase BZ23_3071 ENOG4105P66 Membrane BZ23_3072 ENOG4105CTX dehydratase BZ23_3073 ENOG4107QZW Altronate oxidoreductase BZ23_3075 ENOG4105DPW Major facilitator superfamily MFS_1 BZ23_3078 ENOG4106W5V Membrane BZ23_3081 ENOG4105NE1 Conserved Protein BZ23_3082 ENOG41090KG Inner membrane protein YqjE BZ23_3084 ENOG4108VBZ doxx family BZ23_3085 ENOG4105CHF Glutathione S-transferase BZ23_3086 ENOG4105CWB LysR family transcriptional Regulator BZ23_3087 ENOG4108CNN domain protein BZ23_3088 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BZ23_309 ENOG4107VXZ Hydrolase BZ23_3092 ENOG4105W4M Transport-associated protein BZ23_3094 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BZ23_3095 ENOG4105BZU Histidine kinase BZ23_3097 ENOG4105N5T Radical SAM Protein BZ23_3098 ENOG4105CBC glutamate synthase BZ23_3099 ENOG4105BZ8 glutamate synthase BZ23_310 ENOG4105W39 Membrane BZ23_3101 ENOG4105KB2 stringent starvation protein b BZ23_3102 ENOG4107MKT Stringent starvation protein a BZ23_3105 ENOG4105D6Z AFG1 family ATPase BZ23_3106 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III BZ23_3107 ENOG4105C0H protease BZ23_3108 ENOG4105C0H protease BZ23_3110 ENOG4105VFK BolA family BZ23_3111 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane BZ23_3112 ENOG4105E3I toluene tolerance BZ23_3113 ENOG4107PE3 Mammalian cell entry related domain protein BZ23_3114 ENOG4105CY3 ABC transporter, permease BZ23_3115 ENOG4105DHJ ABC, transporter BZ23_3116 ENOG4105FEU K -dependent Na -Ca exchanger BZ23_3117 ENOG4105C2X Arabinose 5-phosphate isomerase BZ23_3118 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BZ23_3119 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) BZ23_3120 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BZ23_3121 ENOG4108IUZ ABC transporter BZ23_3122 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ23_3123 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BZ23_3124 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BZ23_3126 ENOG41080Z8 PHOSPHOCARRIER protein BZ23_3129 ENOG4105KME endoribonuclease L-psp BZ23_313 ENOG4108JU6 CBS domain protein BZ23_3131 ENOG4105D4X repressor BZ23_3132 ENOG4105C5Y PTS System BZ23_3133 ENOG4105CG3 alpha amylase, catalytic region BZ23_3135 ENOG4105NXH GreA GreB family elongation factor BZ23_3136 ENOG4108XVM Cytochrome b(562) BZ23_3138 ENOG4105CMS peptidase U62, modulator of DNA gyrase BZ23_314 ENOG4106KVJ cytochrome C assembly protein BZ23_3140 ENOG4105UNR (Barnase) inhibitor BZ23_3146 ENOG4105CR8 Transcriptional regulator BZ23_315 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BZ23_3157 ENOG4105D1U peptidase U62 modulator of DNA gyrase BZ23_3159 ENOG4105QD6 exported protein BZ23_3160 ENOG4105C03 ribonuclease BZ23_3162 ENOG4105VQ7 Rod shape-determining protein MreD BZ23_3163 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BZ23_3164 ENOG4105DFF Rod shape-determining protein mreb BZ23_3165 ENOG41062P1 Diguanylate cyclase phosphodiesterase BZ23_3166 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family BZ23_3170 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BZ23_3171 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BZ23_3173 ENOG4105RG0 Membrane BZ23_3174 ENOG4108IA2 Sodium pantothenate symporter BZ23_3176 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ23_3177 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BZ23_3180 ENOG4105CSH Transporter BZ23_3181 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BZ23_3184 ENOG4108XTF Outer Membrane Lipoprotein BZ23_3185 ENOG4105VEQ Cold shock protein BZ23_3186 ENOG4105VEQ Cold shock protein BZ23_3187 ENOG4105VEQ Cold shock protein BZ23_3190 ENOG4105CYM Glutathione S-transferase BZ23_3191 ENOG4105C2X Arabinose 5-phosphate isomerase BZ23_3192 ENOG4105EF1 ribulokinase BZ23_3194 ENOG4105CNN ABC, transporter BZ23_3195 ENOG4105C2J ABC transporter BZ23_3197 ENOG4105D1S lipid A biosynthesis BZ23_3199 ENOG4105EEQ Na H antiporter BZ23_320 ENOG4108NE3 Salt-induced outer membrane protein BZ23_3200 ENOG4105C7N Xanthine uracil vitamin C permease BZ23_3203 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BZ23_3205 ENOG4105GVF (ABC) transporter BZ23_3207 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ23_3208 ENOG4108RVA ribokinase BZ23_3209 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BZ23_321 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ23_3211 ENOG4107TYG Oxidoreductase domain-containing protein BZ23_3213 ENOG4105CS6 Rhs element vgr protein BZ23_3215 ENOG4105CNA YD repeat protein BZ23_3217 ENOG4105CS6 Rhs element vgr protein BZ23_322 ENOG4108NEV two component transcriptional regulator, LytTR family BZ23_3222 ENOG4105CNA YD repeat protein BZ23_3224 ENOG4105CS6 Rhs element vgr protein BZ23_3226 ENOG4105TIV Cryptic phage CTXphi transcriptional repressor RstR BZ23_323 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ23_3233 ENOG4105CS6 Rhs element vgr protein BZ23_3239 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ23_324 ENOG4105EHE chorismate mutase- prephenate dehydrogenase BZ23_3249 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ23_3251 ENOG4107W52 maltose operon periplasmic protein BZ23_3254 ENOG4107FKK extracellular solute-binding protein family 1 BZ23_3255 ENOG4105D56 permease protein BZ23_3256 ENOG4105EG2 ABC transporter, permease BZ23_3259 ENOG4105CFH Aspartokinase BZ23_326 ENOG4108RS6 transposase BZ23_3262 ENOG4105C3R Methionine synthase BZ23_3263 ENOG41069M3 Transcriptional regulator BZ23_3265 ENOG4108I9X Isocitrate lyase BZ23_3266 ENOG4107QP3 malate synthase g BZ23_327 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ23_3278 ENOG4108Z0R Transferase BZ23_328 ENOG4108IMY Transcriptional regulator BZ23_3281 ENOG4108WI1 Dna topoisomerase BZ23_3283 ENOG4105C79 DNA protecting protein DprA BZ23_3287 ENOG4105C1A potassium transporter peripheral membrane BZ23_3289 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system BZ23_3290 ENOG4105W1Y Transcriptional regulator BZ23_3293 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BZ23_3296 ENOG41067V7 50S ribosomal protein L36 BZ23_3297 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BZ23_3299 ENOG4105VPB 50S ribosomal protein L30 BZ23_33 ENOG4105DKT Transcriptional regulator BZ23_3308 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BZ23_3310 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BZ23_3311 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BZ23_3313 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BZ23_3323 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BZ23_3328 ENOG4105WWK YheO domain protein BZ23_3329 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ23_3331 ENOG4108YZY peptidylprolyl cis-trans isomerase BZ23_3332 ENOG4105VKU nucleicacid-binding protein BZ23_3335 ENOG4105C5H ABC transporter BZ23_3336 ENOG4105K64 Glycosyl transferase, family 2 BZ23_3338 ENOG4105E2B Taurine dioxygenase BZ23_3339 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ23_334 ENOG4108IRC dna polymerase iii BZ23_3341 ENOG4106FTQ Taurine ABC transporter, periplasmic BZ23_3343 ENOG4105DNZ Alpha Beta Hydrolase BZ23_3345 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) BZ23_335 ENOG4105DFE Dna adenine methylase BZ23_3350 ENOG410613R integral membrane protein, YccS YhfK family BZ23_3351 ENOG4105C8Y Acetylornithine aminotransferase BZ23_3353 ENOG4105D7A ATP-binding protein BZ23_3354 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ23_3355 ENOG4105F8D glycoside hydrolase family 4 BZ23_3356 ENOG41060NJ transcriptional regulator BZ23_3359 ENOG4105DZC cytosine deaminase BZ23_336 ENOG4105VZ1 Replication Protein BZ23_3360 ENOG4107QZF nitrite reductase NADPH large subunit BZ23_3361 ENOG4105WZK nitrite reductase NADPH small subunit BZ23_3362 ENOG4107V9H nitrite transporter BZ23_3364 ENOG4105C31 Tryptophanyl-tRNA synthetase BZ23_3366 ENOG4105DJV ribulose-phosphate 3-epimerase BZ23_3371 ENOG4105E4G Type IV pilus BZ23_3376 ENOG4108JQC penicillin-binding protein 1A BZ23_3377 ENOG4107RK2 ADP-ribose diphosphatase NudE BZ23_3379 ENOG4105DQY intracellular growth attenuator BZ23_338 ENOG4105ED4 portal protein BZ23_3380 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 BZ23_3381 ENOG4105VEJ Heat shock protein BZ23_3384 ENOG4105E0F Histidine kinase BZ23_3385 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ23_3386 ENOG4108RRZ Transcription elongation factor GreB BZ23_3387 ENOG4105BZM domain protein BZ23_3388 ENOG4105XFK Ferrous iron transport protein A BZ23_3389 ENOG4105CE1 Ferrous iron transport protein b BZ23_3391 ENOG4105RID UPF0379 protein yhcN BZ23_3393 ENOG4105MJ2 Competence protein BZ23_3395 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) BZ23_3396 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ23_3400 ENOG4105E98 transcriptional regulator DeoR family BZ23_3403 ENOG4105DQ6 Transposase BZ23_3407 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BZ23_3408 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ23_3413 ENOG4108HRK Histidine kinase BZ23_3415 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ23_3416 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BZ23_3420 ENOG4105GMB type VI secretion system effector, hcp1 family BZ23_3422 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ23_3423 ENOG4105C6Z Gluconate BZ23_3424 ENOG4105DIQ Transcriptional regulator BZ23_3425 ENOG4105C2I pirin domain protein BZ23_3427 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ23_3429 ENOG4105D2N Aldolase BZ23_3431 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ23_3432 ENOG4105CNN ABC, transporter BZ23_3435 ENOG4105CBX hi0933 family BZ23_3436 ENOG4105CJ3 phosphate transporter BZ23_3438 ENOG4108M6U Universal stress protein A BZ23_3442 ENOG4105DGW oligopeptidase A BZ23_3443 ENOG4105D6S protein involved in catabolism of external DNA BZ23_3444 ENOG4105DC8 reductase BZ23_3445 ENOG4107VHA regulatoR BZ23_3446 ENOG4107QQ0 gntp family BZ23_3447 ENOG4105BZW Glycerate kinase BZ23_3453 ENOG4107H3J ribonuclease BZ23_3454 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) BZ23_3455 ENOG41066T0 asmA family BZ23_3456 ENOG4105CMB EAL domain-containing protein BZ23_3457 ENOG4105VSH 4-oxalocrotonate tautomerase BZ23_3458 ENOG4107SS6 2-dehydro-3-deoxygluconokinase BZ23_3459 ENOG4105CS0 peptidase BZ23_3464 ENOG4108PU9 oligogalacturonate-specific porin BZ23_3465 ENOG4105BZU Histidine kinase BZ23_3466 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BZ23_3467 ENOG4108JQ7 (ABC) transporter BZ23_3468 ENOG4105C3U ABC transporter BZ23_3469 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ23_3470 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ23_3471 ENOG4105DEF Extracellular solute-binding protein, family 5 BZ23_3473 ENOG4105D5K Hemolysin activator protein BZ23_3474 ENOG4105CKT filamentous hemagglutinin BZ23_3475 ENOG4108RS6 transposase BZ23_3476 ENOG4108RS6 transposase BZ23_3478 ENOG4105CXY transporter BZ23_3479 ENOG4105BZU Histidine kinase BZ23_3480 ENOG4108KX4 response regulator BZ23_3481 ENOG4105DIJ Phosphoethanolamine transferase BZ23_3483 ENOG4105C85 amino acid BZ23_3486 ENOG4105C6T cysteine synthase BZ23_3492 ENOG4105CM4 permease protein BZ23_3494 ENOG4108IPW abc transporter atp-binding protein BZ23_3497 ENOG4105DFP Integrase BZ23_3499 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures BZ23_35 ENOG4105DKP glycosyl transferase, family 9 BZ23_3501 ENOG4108XS9 dna repair protein BZ23_3507 ENOG4108RS6 transposase BZ23_3508 ENOG4106H3A restriction BZ23_3510 ENOG4105DZR Type I site-specific deoxyribonuclease BZ23_3512 ENOG4107XZC Restriction modification system DNA (Specificity BZ23_3516 ENOG4105DFP Integrase BZ23_3518 ENOG4105T16 Transcriptional regulator (AraC family) BZ23_3519 ENOG4107RNG ABC transporter BZ23_3521 ENOG4105DFW ABC transporter BZ23_3523 ENOG4105CMG Carbohydrate kinase BZ23_3525 ENOG4108TTM chaperone BZ23_3527 ENOG4106EAR Fimbrial protein BZ23_3528 ENOG4105MEV Acyl-transferase BZ23_3534 ENOG4105D13 transposase BZ23_3535 ENOG4105EM7 Selenocysteine-specific translation elongation factor BZ23_3538 ENOG4108MG3 formate dehydrogenase BZ23_3539 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BZ23_3540 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ23_3541 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ23_3543 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ23_3544 ENOG4105C8Q Methyl-accepting chemotaxis BZ23_3548 ENOG4108YYI Protein of unknown function (DUF2810) BZ23_3550 ENOG4105E61 Mannitol repressor protein BZ23_3552 ENOG4105CTS PTS system mannitol-specific BZ23_3553 ENOG4106JH6 (LipO)protein BZ23_3556 ENOG4108R3E Dna-3-methyladenine glycosylase i BZ23_3558 ENOG4108ZG0 Ompa motb domain protein BZ23_356 ENOG4108X9F tail fiber protein BZ23_3561 ENOG4107T9C Alpha amylase catalytic region BZ23_3563 ENOG4105JKW Valine--pyruvate aminotransferase BZ23_3567 ENOG4105R2A (LipO)protein BZ23_3568 ENOG4105D99 atp gtp-binding protein BZ23_3569 ENOG4105D99 atp gtp-binding protein BZ23_3570 ENOG4105C7B Threonine dehydratase BZ23_3573 ENOG410667J hydrolase BZ23_3574 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ23_3575 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BZ23_3576 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BZ23_3579 ENOG4105VG0 50S ribosomal protein l34 BZ23_3582 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BZ23_3585 ENOG4108RS6 transposase BZ23_3588 ENOG4105C7N Xanthine uracil vitamin C permease BZ23_3589 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 BZ23_3590 ENOG4105DRP amino acid AbC transporter BZ23_3591 ENOG4105EAD ABC transporter BZ23_3592 ENOG4106PMH Extracellular solute-binding protein family 3 BZ23_3596 ENOG4105E2Z phosphate ABC transporter (Permease BZ23_3597 ENOG4105C8U phosphate abc transporter BZ23_3598 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BZ23_3600 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BZ23_3608 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BZ23_361 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA BZ23_3610 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation BZ23_3613 ENOG4105QTB Flavodoxin BZ23_3614 ENOG4108VVK transcriptional Regulator, AsnC BZ23_362 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BZ23_3620 ENOG4108RVA ribokinase BZ23_3621 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ23_3623 ENOG4107EJG GntR family transcriptional regulator BZ23_3629 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b BZ23_363 ENOG4105C34 Pseudouridine synthase BZ23_3631 ENOG4105PC1 Conserved Protein BZ23_3632 ENOG4105E27 serine threonine protein kinase BZ23_3633 ENOG4108Z33 Thiol disulfide Interchange Protein BZ23_3634 ENOG4105C2M dna polymerase I BZ23_3637 ENOG4105D4P Coproporphyrinogen iii oxidase BZ23_3638 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ23_3639 ENOG4105CUX Signal transduction histidine kinase BZ23_364 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ23_3640 ENOG4105C5F glutamine synthetase BZ23_3642 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 BZ23_3645 ENOG4105SUU thioesterase domain BZ23_3646 ENOG4105JV1 AsmA family BZ23_3647 ENOG4105C2W permease BZ23_3648 ENOG4105D6U Sodium Glutamate Symporter BZ23_3649 ENOG4105CB5 ATP-dependent DNA helicase recG BZ23_365 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ23_3650 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase BZ23_3651 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ23_3652 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BZ23_3655 ENOG4105EN6 Membrane BZ23_3656 ENOG4105DSJ YicC domain protein BZ23_3661 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BZ23_3664 ENOG4105W0E 50S ribosomal protein L33 BZ23_3668 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BZ23_3669 ENOG4105D16 lipopolysaccharide heptosyltransferase i BZ23_3670 ENOG4105XA0 heptosyltransferase ii BZ23_3672 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BZ23_3674 ENOG4105PXI polysaccharide deacetylase BZ23_3675 ENOG41063SB peptidase BZ23_3677 ENOG4107YZP Rhodanese domain protein BZ23_3678 ENOG4105VW4 glutaredoxin 3 BZ23_3681 ENOG4105D7W serine acetyltransferase BZ23_3682 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BZ23_3683 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ23_3684 ENOG4105E0F Histidine kinase BZ23_3685 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ23_3686 ENOG4105FMW periplasmic BZ23_3691 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BZ23_3693 ENOG4107QPK )-transporter BZ23_3694 ENOG4105JSC dimethylmenaquinone methyltransferase BZ23_3696 ENOG4107F9Y LysR family transcriptional regulator BZ23_3698 ENOG4105EBK exported protein BZ23_3699 ENOG4108VTS Membrane BZ23_3700 ENOG4105DP0 ferredoxin-NADP reductase BZ23_3701 ENOG4105CBT Fructose-1,6-bisphosphatase BZ23_3702 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BZ23_3703 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BZ23_3705 ENOG4108JJA ABC, transporter BZ23_3706 ENOG4108MBX Secretion Protein BZ23_3710 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BZ23_3713 ENOG41063M6 Cell Division Protein BZ23_3714 ENOG4105ETE Transcriptional regulator (LacI family BZ23_3716 ENOG4105C25 Primosomal protein n' BZ23_3718 ENOG4108Z12 YiaAB two helix domain-containing protein BZ23_3719 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) BZ23_372 ENOG4105T42 (LipO)protein BZ23_3720 ENOG4105C28 cystathionine BZ23_3721 ENOG4105CFH Aspartokinase BZ23_3722 ENOG4105SYT Methylenetetrahydrofolate reductase BZ23_3725 ENOG4105DQ6 Transposase BZ23_373 ENOG4105JIM Phosphatidylserine synthase BZ23_3731 ENOG4105X58 receptor BZ23_3734 ENOG4107QZV Type I secretion membrane fusion protein BZ23_3735 ENOG4105YHG TonB family BZ23_3736 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ23_3737 ENOG4105EHV domain protein BZ23_3739 ENOG4105C5Q Transcriptional regulator BZ23_374 ENOG4105CD5 CoA-binding domain protein BZ23_3742 ENOG4108Y73 Membrane BZ23_375 ENOG4106IUH DTW domain containing protein BZ23_3752 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator BZ23_3753 ENOG4105C2J ABC transporter BZ23_3754 ENOG4107R9N ABC transporter BZ23_3756 ENOG41062B0 ABC transporter, permease BZ23_3757 ENOG4108WFC UPF0438 protein yifE BZ23_3758 ENOG4105C0P Mg chelatase subunit ChlI BZ23_376 ENOG4105K63 Thioredoxin BZ23_3760 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit BZ23_3761 ENOG4105CM2 brancheD-chain amino acid aminotransferase BZ23_3763 ENOG4105C7B Threonine dehydratase BZ23_3769 ENOG4105EMY transcriptional regulator BZ23_377 ENOG4105EIB trna rrna methyltransferase BZ23_3771 ENOG4108MA7 Inherit from COG: YD repeat protein BZ23_3779 ENOG4108VEV chaperone BZ23_378 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ23_3781 ENOG4105CW0 outer membrane usher protein BZ23_3782 ENOG4105GQR Chaperone BZ23_3785 ENOG4105KQ5 peptidylprolyl cis-trans isomerase BZ23_3786 ENOG4105C4R Atp-dependent dna helicase BZ23_3789 ENOG4105K63 Thioredoxin BZ23_379 ENOG4105CW7 secretion protein, HlyD family BZ23_3791 ENOG4105ESV Glycosyl transferase, family 4 BZ23_3792 ENOG4105SFE lipopolysaccharide biosynthesis protein BZ23_3793 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BZ23_3794 ENOG4108IJ1 Dehydrogenase BZ23_3795 ENOG4105C1B dTDP-glucose 4-6-dehydratase BZ23_3796 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BZ23_3797 ENOG4108WJ1 acetyltransferase BZ23_3798 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ23_3799 ENOG4105EGZ biosynthesis protein BZ23_38 ENOG410624X efflux transporter, rnd family, mfp subunit BZ23_380 ENOG4105NTK Transcriptional repressor Mpra BZ23_3803 ENOG4105C85 amino acid BZ23_3808 ENOG4108RS6 transposase BZ23_3809 ENOG410601J HemY protein BZ23_381 ENOG4105ZED uncharacterized protein ygaH BZ23_3810 ENOG4105ECF c-methyltransferase BZ23_3811 ENOG41076E6 Uroporphyrinogen-III Synthase BZ23_3813 ENOG4107T0K Adenylate cyclase BZ23_3816 ENOG4105S7Z (LipO)protein BZ23_3818 ENOG4105CT0 Protein of unknown function, DUF484 BZ23_3819 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ23_382 ENOG4108UMN azlc family BZ23_3820 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant BZ23_3821 ENOG4105C4R Atp-dependent dna helicase BZ23_3823 ENOG4105EQN UPF0261 protein BZ23_3825 ENOG4107QUT magnesium and cobalt transport protein CorA BZ23_3826 ENOG4105FR1 rard protein BZ23_3827 ENOG4108VUY thioesterase Superfamily protein BZ23_3828 ENOG4105HDD phospholipase BZ23_3829 ENOG4105C9U ATP-dependent DNA helicase RecQ BZ23_383 ENOG4105EQ0 Major Facilitator superfamily BZ23_3830 ENOG4105CCF Lysine exporter protein (Lyse ygga) BZ23_3832 ENOG4108EUD Lysophospholipase BZ23_3833 ENOG4105DQF Hydrolase BZ23_3835 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BZ23_3836 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A BZ23_3838 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BZ23_3839 ENOG4108W1V Lipoprotein BZ23_3840 ENOG4105EX9 Membrane BZ23_3843 ENOG4107FS9 Membrane BZ23_3846 ENOG4105MG3 Membrane BZ23_3847 ENOG4106H78 methyltransferase BZ23_3848 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ23_3848 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ23_3849 ENOG4105CAK Cell division ATP-binding protein ftsE BZ23_3850 ENOG4105CRP Part of the ABC transporter FtsEX involved in BZ23_3852 ENOG4105U59 -acetyltransferase BZ23_3853 ENOG4105CP9 extracellular ligand-binding receptor BZ23_3854 ENOG4105C32 Amino acid ABC transporter (Permease) BZ23_3855 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BZ23_3856 ENOG4105C0Z ABC transporter BZ23_3857 ENOG4108IV0 ABC, transporter BZ23_3869 ENOG4107T6V glycerophosphoryl diester phosphodiesterase BZ23_3870 ENOG4105RK9 auxin efflux carrier BZ23_3874 ENOG4105DZ2 Transcriptional regulator BZ23_3875 ENOG4105EMK carboxylate amino acid amine transporter BZ23_3877 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) BZ23_3878 ENOG4108I5U Uridine phosphorylase BZ23_388 ENOG4105F87 Dehydratase BZ23_3881 ENOG4108RS6 transposase BZ23_3882 ENOG4108KF1 Membrane BZ23_3883 ENOG4105CGY Dna recombination protein BZ23_3885 ENOG4105JC1 sterol-binding domain protein BZ23_3887 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BZ23_3889 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BZ23_3891 ENOG4105D52 delta-aminolevulinic acid dehydratase BZ23_3892 ENOG4105MDZ Transcriptional activator rfaH BZ23_3894 ENOG4107QK7 reductase BZ23_3898 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BZ23_3899 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BZ23_39 ENOG4105BZS acriflavin resistance protein BZ23_390 ENOG4105E5Q amino acid AbC transporter BZ23_3900 ENOG4108RR8 protoporphyrinogen oxidase BZ23_3907 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BZ23_3915 ENOG4105PM1 preprotein translocase subunit SecE BZ23_3916 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BZ23_392 ENOG4105C5R Aminotransferase BZ23_3924 ENOG4105D41 biosynthesis protein thiH BZ23_3927 ENOG4105D06 uba thif-type nad fad binding protein BZ23_3929 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BZ23_3934 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BZ23_3935 ENOG4105R2J Conserved Protein BZ23_3937 ENOG4108T8B Protein of unknown function (DUF1481) BZ23_3938 ENOG4105C12 Phosphoribosylglycinamide synthetase BZ23_3946 ENOG4105CMM transposase BZ23_3949 ENOG41062QD Membrane BZ23_395 ENOG4105CHM Aminotransferase BZ23_3951 ENOG4105CK2 sodium dicarboxylate symporter BZ23_3952 ENOG4105WH1 Two component transcriptional regulator luxr family BZ23_3953 ENOG4105BZU Histidine kinase BZ23_3965 ENOG4108JIR Flagellum-specific ATP synthase BZ23_3968 ENOG41063Q7 Type III secretion system protein BZ23_3969 ENOG4108HHI Type III secretion system protein BZ23_3970 ENOG41083GP type iii secretion BZ23_3971 ENOG4108TN6 type iii secretion BZ23_3972 ENOG4108IUF type iii secretion BZ23_3973 ENOG41066VF YeeE YedE family protein BZ23_3974 ENOG4105KSU Redox protein BZ23_3975 ENOG4105EQ2 LysR family Transcriptional regulator BZ23_3976 ENOG4105C44 Serine transporter BZ23_3977 ENOG4105C28 cystathionine BZ23_3979 ENOG4105EHG Permease protein BZ23_3980 ENOG4107R4I Periplasmic binding protein BZ23_3981 ENOG4106QJH hemin transport protein BZ23_3982 ENOG4107ENK receptor BZ23_3983 ENOG4107F3C Hemin uptake protein BZ23_3985 ENOG41090JE Utilization Protein BZ23_3986 ENOG4105D4P Coproporphyrinogen iii oxidase BZ23_3990 ENOG4105DAX Pfam:DUF2983 BZ23_4002 ENOG4108S1B Periplasmic chaperone protein BZ23_4009 ENOG41080IJ Diacylglycerol kinase BZ23_4011 ENOG4105MYN Zinc uptake regulation protein BZ23_4012 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ23_4013 ENOG4105P4Z Phage shock protein G BZ23_4014 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BZ23_4015 ENOG4105CDU Replicative dna helicase BZ23_4016 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ23_4017 ENOG4105CGF Aromatic amino acid aminotransferase BZ23_4018 ENOG4105MSB protein, conserved in bacteria BZ23_4019 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BZ23_4020 ENOG4108UUM single-stranded DNA-binding protein BZ23_4022 ENOG4105C0A alcohol dehydrogenase BZ23_403 ENOG4106YJS accessory processing protein BZ23_4035 ENOG4108SIC Transcriptional regulator BZ23_4036 ENOG4105BZ8 glutamate synthase BZ23_4037 ENOG4108RC0 Electron transport protein BZ23_4038 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ23_4041 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ23_4046 ENOG4108ZVF (LipO)protein BZ23_4047 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BZ23_4049 ENOG4105KPY Small multidrug resistance protein BZ23_405 ENOG4107QPN acyl-Coa dehydrogenase BZ23_4050 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) BZ23_4055 ENOG4105EGS Mechanosensitive ion channel BZ23_4064 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BZ23_4065 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BZ23_4066 ENOG4105K8N protein family UPF0079, ATPase BZ23_4067 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ23_407 ENOG4105F7V ErfK ybiS ycfS ynhG family protein BZ23_4071 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BZ23_4072 ENOG4107QJR hflk protein BZ23_4073 ENOG4105EPW hflc protein BZ23_4077 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BZ23_4078 ENOG4105C2N RNA methyltransferase TrmH family group 3 BZ23_4079 ENOG4105CSU acyl-Coa dehydrogenase BZ23_408 ENOG4105E7A Glutamine amidotransferase BZ23_4080 ENOG4105WSB biofilm stress and motility protein A BZ23_4081 ENOG4108MXZ Esterase BZ23_4083 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BZ23_4084 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BZ23_4087 ENOG4105FHY Opacity-associated protein A BZ23_4088 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ23_409 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ23_4090 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BZ23_4091 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BZ23_4092 ENOG4108UUE Transcriptional regulator BZ23_4093 ENOG41061GZ Protein of unknown function (DUF1107) BZ23_4094 ENOG4105C37 (CBS) domain BZ23_4096 ENOG4105CFU surface antigen BZ23_4097 ENOG4105MA0 exported protein BZ23_4098 ENOG4108ZHD aig2 family BZ23_4099 ENOG4105F0N pyrophosphate phospho-hydrolase BZ23_410 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ23_4101 ENOG4105DFU Cell wall formation (By similarity) BZ23_4105 ENOG4105HVQ Regulatory factor of maltose metabolism BZ23_4107 ENOG4105EAH synthase BZ23_411 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ23_4110 ENOG4105QYV Membrane BZ23_4114 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase BZ23_4115 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BZ23_4116 ENOG4105HBR Rna-binding protein BZ23_4118 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BZ23_4119 ENOG4105EEI dihydropteroate synthase BZ23_4125 ENOG4105CHV Transcription elongation factor NusA BZ23_4132 ENOG4105C1J atp-dependent rna helicase BZ23_4135 ENOG4105DEN Luciferase family BZ23_4138 ENOG4105BZS acriflavin resistance protein BZ23_4139 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BZ23_4140 ENOG4106RZ4 Peptidase U32 BZ23_4141 ENOG4105CFP Peptidase U32 BZ23_4142 ENOG4105XPQ lipid carrier protein BZ23_4143 ENOG4108YYD acetyltransferase BZ23_4148 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BZ23_4149 ENOG4105DRS transport system, permease BZ23_415 ENOG4105CJ2 (LipO)protein BZ23_4153 ENOG4105K4T epimerase BZ23_4154 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein BZ23_4155 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) BZ23_4156 ENOG4105FD8 phosphonate metabolism protein PhnM BZ23_4157 ENOG4105HRV phosphonate c-p lyase system protein phnl BZ23_4158 ENOG4105ENV phosphonate C-P lyase system protein PhnK BZ23_4159 ENOG4105FT8 Phosphonate metabolism BZ23_4160 ENOG4105EKV Phosphonate metabolism protein BZ23_4161 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH BZ23_4162 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG BZ23_4163 ENOG4107RJJ Transcriptional regulator BZ23_4165 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BZ23_4166 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BZ23_4167 ENOG4108JQ7 (ABC) transporter BZ23_4168 ENOG4105C3U ABC transporter BZ23_4169 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ23_419 ENOG4105CIN aminoacyl-histidine dipeptidase BZ23_42 ENOG4105BZU Histidine kinase BZ23_43 ENOG4105YBH Protein of unknown function (DUF1435) BZ23_430 ENOG4105F2W methyltransferase BZ23_435 ENOG4105DKQ ROK family BZ23_436 ENOG4105EYH Exonuclease BZ23_437 ENOG4107RH8 nuclease SbcCD subunit D BZ23_438 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BZ23_439 ENOG4105BZU Histidine kinase BZ23_441 ENOG4105CWM branched-chain amino acid transport system II carrier protein BZ23_442 ENOG4105C85 amino acid BZ23_443 ENOG4107R28 alpha amylase, catalytic region BZ23_444 ENOG4105CHR reductase BZ23_446 ENOG4105D3R alkyl hydroperoxide reductase BZ23_450 ENOG4105VIE preprotein translocase, subunit YajC BZ23_451 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ23_452 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ23_455 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BZ23_458 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BZ23_459 ENOG4108ZAI phosphatidylglycerophosphatase a BZ23_461 ENOG4105CTB Polyprenyl synthetase BZ23_464 ENOG4107S0N DJ-1 family BZ23_465 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BZ23_467 ENOG4107RDB Major Facilitator BZ23_469 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BZ23_470 ENOG4105CCU oxidase (Subunit III) BZ23_471 ENOG4105BZ9 Cytochrome C oxidase, subunit I BZ23_472 ENOG4105E2S oxidase) subunit II BZ23_473 ENOG4108NFH Sugar hydrolase BZ23_474 ENOG4105EYM Major Facilitator superfamily BZ23_475 ENOG4105IEY (LipO)protein BZ23_476 ENOG4105M85 Bola protein BZ23_48 ENOG4108WPU DNA polymerase III subunit psi BZ23_481 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BZ23_482 ENOG4105K70 DNA-binding protein BZ23_483 ENOG4105EIN peptidylprolyl cis-trans isomerase BZ23_484 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BZ23_485 ENOG4108TGP Thioesterase superfamily protein BZ23_487 ENOG4108NFA extracellular solute-binding protein BZ23_489 ENOG4105C6T cysteine synthase BZ23_49 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BZ23_490 ENOG4108XM1 transcriptional regulator AsnC family BZ23_491 ENOG4105BZ1 (ABC) transporter BZ23_492 ENOG4105BZ1 (ABC) transporter BZ23_493 ENOG4108YZA Nitrogen regulatory protein pii BZ23_494 ENOG4105BZU Histidine kinase BZ23_495 ENOG4105C29 acyl-CoA thioesterase BZ23_496 ENOG4108MNP Glycoprotein polysaccharide metabolism BZ23_497 ENOG41080UX Methyltransferase BZ23_498 ENOG4105KF5 hemolysin expression-modulating protein BZ23_499 ENOG4108UKR Biofilm formation regulator YbaJ BZ23_5 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) BZ23_501 ENOG4105YK5 50S ribosomal protein L36 BZ23_503 ENOG4105BZS acriflavin resistance protein BZ23_504 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ23_505 ENOG4108IG5 Transcriptional regulator BZ23_506 ENOG41090EX DsrE family BZ23_507 ENOG4105EGS Mechanosensitive ion channel BZ23_509 ENOG4105WD1 Membrane BZ23_51 ENOG4105K3G Periplasmic Protein BZ23_511 ENOG4107QMP dna polymerase iii subunits gamma and tau BZ23_518 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BZ23_519 ENOG4105FAW cDP-glucose 4,6-dehydratase BZ23_520 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ23_521 ENOG4108SMP Nad-dependent epimerase dehydratase BZ23_525 ENOG4107Y2G Glycosyl transferase (Group 1 BZ23_528 ENOG4108I2E Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) BZ23_53 ENOG4108NRW Phospholipase, patatin family BZ23_533 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BZ23_535 ENOG4108QY5 Ferric enterobactin transport protein BZ23_536 ENOG4107RE1 Inosine-guanosine kinase BZ23_537 ENOG4105CKD glutathione-regulated potassium-efflux system protein BZ23_538 ENOG4105EU0 Major facilitator Superfamily BZ23_539 ENOG4105CGH 5'-nucleotidase BZ23_54 ENOG4105EYA deoxyribonuclease BZ23_540 ENOG4105CGH 5'-nucleotidase BZ23_543 ENOG4108Z66 YbaK ebsC protein BZ23_544 ENOG4105MBR gumn family BZ23_545 ENOG4105C59 p-type ATPase BZ23_546 ENOG4108Z6Z Transcriptional regulator BZ23_547 ENOG4105G5H Membrane BZ23_548 ENOG4107QX8 SPFH domain, Band 7 family protein BZ23_549 ENOG4107QR8 Thioredoxin BZ23_55 ENOG4105D9N nucleoside BZ23_550 ENOG4105E1F short-chain dehydrogenase reductase BZ23_551 ENOG4108UJV acyl-CoA thioesterase i BZ23_552 ENOG4108I0Y (ABC) transporter BZ23_553 ENOG4105CV6 ABC transporter, permease BZ23_554 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BZ23_555 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BZ23_557 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ23_559 ENOG4105WQ3 Rna-binding protein BZ23_56 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ23_567 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase BZ23_568 ENOG4108HPI phosphatidate Cytidylyltransferase BZ23_570 ENOG4105E8V Alpha Beta Hydrolase Fold protein BZ23_571 ENOG41077RS Phosphatase BZ23_575 ENOG4105EQ2 LysR family Transcriptional regulator BZ23_576 ENOG4107SET aldo keto reductase BZ23_579 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ23_582 ENOG4105FE9 pseudouridine synthase BZ23_583 ENOG4105EZE Cupin 4 family protein BZ23_587 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ23_593 ENOG4105HVQ Regulatory factor of maltose metabolism BZ23_594 ENOG4108JQB penicillin-binding protein 1C BZ23_596 ENOG4108RS6 transposase BZ23_597 ENOG4105DN3 alpha-2-macroglobulin domain protein BZ23_599 ENOG4105C26 Dehydrogenase BZ23_6 ENOG4108MJ3 acetyltransferase BZ23_60 ENOG41062Z9 Membrane BZ23_600 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BZ23_602 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ23_603 ENOG4105C2J ABC transporter BZ23_604 ENOG4105CNN ABC, transporter BZ23_605 ENOG4105CK5 oxidoreductase BZ23_606 ENOG4105EDK PfkB domain protein BZ23_608 ENOG4105DH8 myo-inositol catabolism BZ23_61 ENOG4105EAC phosphoserine phosphatase BZ23_610 ENOG4108JJ7 ABC transporter BZ23_614 ENOG4108N8T regulatoR BZ23_616 ENOG4105VEQ Cold shock protein BZ23_618 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) BZ23_62 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BZ23_622 ENOG4105DZ1 carboxypeptidase BZ23_623 ENOG4105K6T rare lipoprotein A BZ23_624 ENOG4105CNI cell division protein FtsW BZ23_625 ENOG4105CJN penicillin-binding protein BZ23_627 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BZ23_629 ENOG4105DJF DNA polymerase III, delta' subunit BZ23_63 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase BZ23_632 ENOG4107PAI alpha helical protein BZ23_633 ENOG4105CDA abc transporter atp-binding protein BZ23_634 ENOG4105DRP amino acid AbC transporter BZ23_635 ENOG4105EAD ABC transporter BZ23_636 ENOG4107RP9 extracellular solute-binding protein, family 3 BZ23_637 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BZ23_638 ENOG4108JU5 Magnesium and cobalt efflux protein BZ23_640 ENOG4105C9A Phoh family BZ23_642 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ23_649 ENOG4105CAQ asparagine synthetase BZ23_65 ENOG4105C5H ABC transporter BZ23_650 ENOG4105D4U had-superfamily hydrolase, subfamily iia BZ23_651 ENOG4105E2R ROK family BZ23_652 ENOG4105CE4 GlcNAc 6-P deacetylase BZ23_654 ENOG4105CI1 PTS System BZ23_658 ENOG41090R7 Ferric uptake BZ23_659 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) BZ23_66 ENOG41090EK ompa motb domain protein BZ23_660 ENOG4105NNH LexA regulated protein BZ23_662 ENOG4105EV9 Alpha Beta Hydrolase BZ23_665 ENOG4105DFP Integrase BZ23_666 ENOG4107R08 Integrase BZ23_67 ENOG4108KHX Diguanylate cyclase BZ23_673 ENOG4108R7K Metal Dependent Phosphohydrolase BZ23_674 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) BZ23_675 ENOG4105H40 BZ23_681 ENOG4108S1U BZ23_682 ENOG4105CAR Terminase, large subunit BZ23_687 ENOG4108MXB Protein of unknown function (DUF968) BZ23_688 ENOG4105HRS Antitermination protein BZ23_692 ENOG4105NVB glycoside hydrolase, family 19 BZ23_70 ENOG4107SC1 transglycosylase BZ23_708 ENOG4105TKZ Tail Sheath BZ23_717 ENOG4108T86 baseplate J family protein BZ23_72 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) BZ23_720 ENOG4105PTU response to oxidative stress BZ23_722 ENOG4108Z1B Cyclase dehydrase BZ23_724 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ23_725 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BZ23_726 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BZ23_728 ENOG4105BZN citrate synthase BZ23_729 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BZ23_73 ENOG4105UEI Transcriptional Regulator AraC Family BZ23_730 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BZ23_732 ENOG4105E33 succinate dehydrogenase BZ23_733 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BZ23_734 ENOG4105C7S Dehydrogenase BZ23_736 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BZ23_737 ENOG4105C4M (Ubiquinol oxidase) subunit I BZ23_738 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BZ23_740 ENOG4105KJB cyd operon protein YbgE BZ23_741 ENOG4107YD3 Thioesterase BZ23_742 ENOG4105E02 MotA TolQ exbB proton channel BZ23_743 ENOG4105M8F Biopolymer transport protein exbD tolR BZ23_744 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ23_744 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ23_746 ENOG4105KCK Peptidoglycan-associated lipoprotein BZ23_747 ENOG4105UFD tol-pal system protein YbgF BZ23_754 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BZ23_755 ENOG4105PGM cation diffusion facilitator family transporter BZ23_757 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ23_76 ENOG4108RH0 Crea protein BZ23_760 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BZ23_762 ENOG4105F0Z galactose-1-phosphate uridylyltransferase BZ23_763 ENOG4105CMR udp-glucose 4-epimerase BZ23_766 ENOG4105DKW ABC transporter BZ23_767 ENOG4105F4R Transcriptional regulator mode BZ23_768 ENOG410680R Protein of unknown function (DUF2592) BZ23_769 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BZ23_77 ENOG41065U4 response regulator BZ23_770 ENOG4105E0C molybdate abc transporter BZ23_772 ENOG4108K4B hydrolase BZ23_777 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BZ23_778 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ23_779 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BZ23_781 ENOG4105VYA Uncharacterized conserved protein (DUF2132) BZ23_782 ENOG4105CHW UPF0052 protein BZ23_784 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BZ23_786 ENOG4105M00 molybdopterin converting factor, subunit 1 BZ23_787 ENOG4108ZAF Molybdopterin BZ23_788 ENOG4105HFZ Membrane BZ23_792 ENOG4105C94 Transporter BZ23_793 ENOG4105CN8 Transcriptional regulator BZ23_795 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BZ23_796 ENOG4105EAA nucleoside BZ23_798 ENOG4105BZU Histidine kinase BZ23_8 ENOG4105MYG DNA polymerase iii, chi subunit BZ23_800 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ23_803 ENOG4107QWP ABC-2 type transporter BZ23_804 ENOG4107QWP ABC-2 type transporter BZ23_805 ENOG4105CJ1 ABC, transporter BZ23_807 ENOG4107MVR Transcriptional regulator BZ23_808 ENOG4105C1J atp-dependent rna helicase BZ23_813 ENOG4105EQR Transposase IS116 IS110 IS902 BZ23_814 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BZ23_816 ENOG41061WM D-Alanyl-D-Alanine BZ23_817 ENOG4105CXG d-lactate dehydrogenase BZ23_819 ENOG4105N1F Hnh endonuclease BZ23_821 ENOG4105Y3U Transglycosylase-associated protein BZ23_823 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein BZ23_826 ENOG4108W15 Protein of unknown function (DUF1456) BZ23_828 ENOG4105C32 Amino acid ABC transporter (Permease) BZ23_829 ENOG4105CNN ABC, transporter BZ23_830 ENOG4108JJB ABC transporter BZ23_831 ENOG4108IV0 ABC, transporter BZ23_834 ENOG4105KHC sulfurtransferase BZ23_835 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BZ23_836 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component BZ23_837 ENOG4108IJ8 ABC transporter BZ23_838 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component BZ23_839 ENOG4105D5Q Arginine ornithine antiporter BZ23_840 ENOG4105CXN decarboxylase BZ23_842 ENOG4105FDR Membrane BZ23_845 ENOG4105DVT helicase BZ23_846 ENOG4105CH6 catalase BZ23_847 ENOG4108UII YfaZ family BZ23_848 ENOG4108RS6 transposase BZ23_849 ENOG4105E0U tyrosine-specific transport protein BZ23_85 ENOG4108RIR Molybdenum cofactor biosynthesis protein BZ23_852 ENOG4105XPH Ferredoxin BZ23_853 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ23_854 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ23_856 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ23_857 ENOG4105BZU Histidine kinase BZ23_858 ENOG41068CG regulatoR BZ23_859 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC BZ23_860 ENOG4106UW1 Major Facilitator superfamily BZ23_862 ENOG4105FCK Membrane BZ23_865 ENOG4107R6D beta-lactam binding protein AmpH BZ23_866 ENOG4105CT4 transporter BZ23_868 ENOG4105C8Q Methyl-accepting chemotaxis BZ23_871 ENOG4105Y50 Virulence Protein BZ23_873 ENOG4105HRS Antitermination protein BZ23_874 ENOG4105G63 Type III effector Hrp-dependent BZ23_876 ENOG4105MVE transcriptional regulator BZ23_877 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BZ23_88 ENOG4106HK8 GPR1 FUN34 yaaH family protein BZ23_881 ENOG4105TKZ Tail Sheath BZ23_889 ENOG4108T86 baseplate J family protein BZ23_892 ENOG4108Q3X Transcriptional regulator BZ23_894 ENOG4105CS2 ec 3.2.1.21 BZ23_899 ENOG4105GMB type VI secretion system effector, hcp1 family BZ23_902 ENOG4105E68 Sulfatase BZ23_903 ENOG4105PAN UPF0352 protein BZ23_906 ENOG4105CFI type iii restriction protein res subunit BZ23_907 ENOG4105I08 Pseudouridine synthase BZ23_908 ENOG4105C2C drug resistance transporter, Bcr CflA BZ23_909 ENOG4105HG6 BZ23_910 ENOG4108JQ5 ABC transporter BZ23_911 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BZ23_912 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BZ23_913 ENOG4105E43 Extracellular solute-binding protein, family 5 BZ23_914 ENOG4105CXC rtn protein BZ23_915 ENOG4107TT5 NLP P60 protein BZ23_916 ENOG41076MN Phosphoesterase, PA-phosphatase related BZ23_917 ENOG4105CKI cobalamin synthesis protein BZ23_919 ENOG4107YCY Transcriptional regulator BZ23_92 ENOG41063Z6 transcriptional regulator, lysR family BZ23_920 ENOG4105DEI Mannitol dehydrogenase BZ23_924 ENOG4105KRS Proteinase inhibitor BZ23_925 ENOG4105CHR reductase BZ23_928 ENOG4105C26 Dehydrogenase BZ23_930 ENOG4105E66 phosphoriboisomerase A BZ23_932 ENOG4105C2J ABC transporter BZ23_933 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BZ23_935 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein BZ23_936 ENOG4105DE4 1-phosphofructokinase BZ23_937 ENOG4105DM4 PTS System BZ23_938 ENOG4108RS6 transposase BZ23_939 ENOG4108SGD regulatory protein BZ23_94 ENOG4105DTN riboflavin biosynthesis protein ribF BZ23_942 ENOG4108UIF Chaperone BZ23_943 ENOG4108D1K outer membrane usher protein BZ23_945 ENOG4105HMI Membrane BZ23_946 ENOG4105DUM transcriptional regulator, lysR family BZ23_948 ENOG4108IQI permease BZ23_950 ENOG4105EHG Permease protein BZ23_952 ENOG4105D05 Receptor BZ23_953 ENOG4108TGY Glutathione S-transferase BZ23_957 ENOG4105D01 (LipO)protein BZ23_959 ENOG4108UMI ABC transporter, permease BZ23_960 ENOG4105DZ1 carboxypeptidase BZ23_961 ENOG4105C44 Serine transporter BZ23_963 ENOG4107FB0 transcriptional regulator DeoR family BZ23_964 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ23_965 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BZ23_967 ENOG4105D0C transport protein BZ23_968 ENOG41090BQ Glutaredoxin BZ23_969 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress BZ23_97 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BZ23_970 ENOG4108RMJ sensory transduction regulator BZ23_971 ENOG4107RUE extracellular solute-binding protein family 1 BZ23_972 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ23_973 ENOG4105F38 ABC transporter, permease BZ23_974 ENOG4105D38 putrescine abc transporter BZ23_975 ENOG4105RBQ inner membrane protein ybjO BZ23_977 ENOG4106TNF Periplasmic binding protein BZ23_980 ENOG4108I9K permease protein BZ23_981 ENOG4105E0A ABC, transporter BZ23_982 ENOG410642S Nicotianamine synthase protein BZ23_983 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) BZ23_984 ENOG4108I0N Transporter, RarD family, DMT superfamily protein BZ23_985 ENOG4105DMR ABC, transporter BZ23_986 ENOG4105GBT ABC transporter BZ23_987 ENOG4106PMH Extracellular solute-binding protein family 3 BZ23_988 ENOG4105E5Z arginine transporter ATP-binding subunit BZ23_989 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) BZ23_990 ENOG41064MM (LipO)protein BZ23_991 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ23_992 ENOG4105CGD Nad-dependent epimerase dehydratase BZ23_993 ENOG4105C5W Aldolase BZ23_994 ENOG4105C7K acetolactate synthase BZ23_995 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ23_997 ENOG4105DWU Membrane BZ23_998 ENOG4105CPB ATP-dependent endonuclease of the OLD family BZ23_999 ENOG4108MJ5 VirK protein