locus-tag class description CEQ20_00010 ENOG4105CMG Carbohydrate kinase CEQ20_00015 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase CEQ20_00020 ENOG4105F5R ABC transporter CEQ20_00025 ENOG4105CNN ABC, transporter CEQ20_00030 ENOG4105C2J ABC transporter CEQ20_00040 ENOG4105E98 transcriptional regulator DeoR family CEQ20_00045 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CEQ20_00050 ENOG4107QY8 reductase CEQ20_00055 ENOG4105QAX Iron-sulfur CEQ20_00060 ENOG4107KGK dmso reductase anchor subunit CEQ20_00065 ENOG4108NEM leader-binding protein dmsD CEQ20_00070 ENOG4105CPW cytochrome b561 CEQ20_00075 ENOG4108XVM Cytochrome b(562) CEQ20_00095 ENOG4105C2J ABC transporter CEQ20_00100 ENOG4105CNN ABC, transporter CEQ20_00105 ENOG4108HHA Transketolase CEQ20_00110 ENOG4108IUS Transketolase CEQ20_00115 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) CEQ20_00160 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) CEQ20_00185 ENOG4107VXZ Hydrolase CEQ20_00190 ENOG4105W39 Membrane CEQ20_00205 ENOG4108JU6 CBS domain protein CEQ20_00210 ENOG4106KVJ cytochrome C assembly protein CEQ20_00215 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY CEQ20_00240 ENOG4108NE3 Salt-induced outer membrane protein CEQ20_00245 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CEQ20_00250 ENOG4108NEV two component transcriptional regulator, LytTR family CEQ20_00255 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CEQ20_00260 ENOG4105EHE chorismate mutase- prephenate dehydrogenase CEQ20_00270 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA CEQ20_00275 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane CEQ20_00285 ENOG4105C34 Pseudouridine synthase CEQ20_00290 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CEQ20_00295 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEQ20_00335 ENOG4105T42 (LipO)protein CEQ20_00340 ENOG4105JIM Phosphatidylserine synthase CEQ20_00345 ENOG4105CD5 CoA-binding domain protein CEQ20_00350 ENOG4106IUH DTW domain containing protein CEQ20_00355 ENOG4105K63 Thioredoxin CEQ20_00360 ENOG4105EIB trna rrna methyltransferase CEQ20_00365 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEQ20_00370 ENOG4105CW7 secretion protein, HlyD family CEQ20_00380 ENOG4105NTK Transcriptional repressor Mpra CEQ20_00385 ENOG4105ZED uncharacterized protein ygaH CEQ20_00390 ENOG4108UMN azlc family CEQ20_00395 ENOG4105EQ0 Major Facilitator superfamily CEQ20_00430 ENOG4105F87 Dehydratase CEQ20_00440 ENOG4105E5Q amino acid AbC transporter CEQ20_00450 ENOG4105C5R Aminotransferase CEQ20_00465 ENOG4105CHM Aminotransferase CEQ20_00510 ENOG4106YJS accessory processing protein CEQ20_00520 ENOG4107QPN acyl-Coa dehydrogenase CEQ20_00530 ENOG4105E7A Glutamine amidotransferase CEQ20_00535 ENOG4105F7V ErfK ybiS ycfS ynhG family protein CEQ20_00545 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CEQ20_00550 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CEQ20_00555 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CEQ20_00575 ENOG4105CJ2 (LipO)protein CEQ20_00595 ENOG4105CIN aminoacyl-histidine dipeptidase CEQ20_00600 ENOG4108KB2 LysR family Transcriptional regulator CEQ20_00650 ENOG4105F2W methyltransferase CEQ20_00680 ENOG4105DKQ ROK family CEQ20_00685 ENOG4105EYH Exonuclease CEQ20_00690 ENOG4107RH8 nuclease SbcCD subunit D CEQ20_00695 ENOG4105CK6 Two component transcriptional regulator (Winged helix family CEQ20_00700 ENOG4105BZU Histidine kinase CEQ20_00710 ENOG4105CWM branched-chain amino acid transport system II carrier protein CEQ20_00715 ENOG4105C85 amino acid CEQ20_00720 ENOG4107R28 alpha amylase, catalytic region CEQ20_00730 ENOG4107FW0 short-chain dehydrogenase reductase CEQ20_00745 ENOG4105D3R alkyl hydroperoxide reductase CEQ20_00750 ENOG4108ZYK Acyl carrier protein phosphodiesterase CEQ20_00755 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) CEQ20_00765 ENOG4105VIE preprotein translocase, subunit YajC CEQ20_00770 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CEQ20_00775 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) CEQ20_00795 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) CEQ20_00810 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) CEQ20_00815 ENOG4108ZAI phosphatidylglycerophosphatase a CEQ20_00825 ENOG4105CTB Polyprenyl synthetase CEQ20_00840 ENOG4107S0N DJ-1 family CEQ20_00845 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) CEQ20_00860 ENOG4107RDB Major Facilitator CEQ20_00870 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) CEQ20_00875 ENOG4105CCU oxidase (Subunit III) CEQ20_00880 ENOG4105BZ9 Cytochrome C oxidase, subunit I CEQ20_00885 ENOG4105E2S oxidase) subunit II CEQ20_00895 ENOG4105EYM Major Facilitator superfamily CEQ20_00900 ENOG4105IEY (LipO)protein CEQ20_00905 ENOG4105M85 Bola protein CEQ20_00930 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) CEQ20_00935 ENOG4105K70 DNA-binding protein CEQ20_00940 ENOG4105EIN peptidylprolyl cis-trans isomerase CEQ20_00945 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein CEQ20_00950 ENOG4108TGP Thioesterase superfamily protein CEQ20_00960 ENOG4108NFA extracellular solute-binding protein CEQ20_00970 ENOG4105C6T cysteine synthase CEQ20_00975 ENOG4108XM1 transcriptional regulator AsnC family CEQ20_00980 ENOG4105BZ1 (ABC) transporter CEQ20_00985 ENOG4105BZ1 (ABC) transporter CEQ20_00990 ENOG4108YZA Nitrogen regulatory protein pii CEQ20_00995 ENOG4105BZU Histidine kinase CEQ20_01000 ENOG4105C29 acyl-CoA thioesterase CEQ20_01005 ENOG4108MNP Glycoprotein polysaccharide metabolism CEQ20_01010 ENOG41080UX Methyltransferase CEQ20_01025 ENOG4105KF5 hemolysin expression-modulating protein CEQ20_01030 ENOG4108UKR Biofilm formation regulator YbaJ CEQ20_01040 ENOG4105YK5 50S ribosomal protein L36 CEQ20_01050 ENOG4105BZS acriflavin resistance protein CEQ20_01055 ENOG4105C1P efflux transporter, rnd family, mfp subunit CEQ20_01060 ENOG4108IG5 Transcriptional regulator CEQ20_01065 ENOG41090EX DsrE family CEQ20_01070 ENOG4105EGS Mechanosensitive ion channel CEQ20_01075 ENOG4106428 Protein of unknown function (DUF2496) CEQ20_01085 ENOG4105WD1 Membrane CEQ20_01095 ENOG4107QMP dna polymerase iii subunits gamma and tau CEQ20_01125 ENOG4108EX3 reductase CEQ20_01130 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase CEQ20_01135 ENOG4105FAW cDP-glucose 4,6-dehydratase CEQ20_01140 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CEQ20_01160 ENOG4107YYJ Glycosyl transferase, family 2 CEQ20_01170 ENOG4108TJN glycosyl transferase group 1 CEQ20_01175 ENOG4105C0K Gdp-mannose 4,6-dehydratase CEQ20_01180 ENOG4105C30 Nad-dependent epimerase dehydratase CEQ20_01185 ENOG4105CJT Mannose-1-phosphate guanylyltransferase CEQ20_01195 ENOG4105DMT epimerase dehydratase CEQ20_01205 ENOG4108QY5 Ferric enterobactin transport protein CEQ20_01210 ENOG4107RE1 Inosine-guanosine kinase CEQ20_01215 ENOG4105CKD glutathione-regulated potassium-efflux system protein CEQ20_01220 ENOG4105EU0 Major facilitator Superfamily CEQ20_01225 ENOG4105CGH 5'-nucleotidase CEQ20_01230 ENOG4105CGH 5'-nucleotidase CEQ20_01240 ENOG4108Z66 YbaK ebsC protein CEQ20_01245 ENOG4105MBR gumn family CEQ20_01250 ENOG4105C59 p-type ATPase CEQ20_01255 ENOG4108Z6Z Transcriptional regulator CEQ20_01260 ENOG4105G5H Membrane CEQ20_01265 ENOG4107QX8 SPFH domain, Band 7 family protein CEQ20_01270 ENOG4107QR8 Thioredoxin CEQ20_01275 ENOG4105E1F short-chain dehydrogenase reductase CEQ20_01280 ENOG4108UJV acyl-CoA thioesterase i CEQ20_01285 ENOG4108I0Y (ABC) transporter CEQ20_01290 ENOG4105CV6 ABC transporter, permease CEQ20_01295 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit CEQ20_01300 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) CEQ20_01315 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CEQ20_01325 ENOG4105WQ3 Rna-binding protein CEQ20_01340 ENOG4105DFP Integrase CEQ20_01345 ENOG4105DFP Integrase CEQ20_01400 ENOG4108MXD gtp-binding protein CEQ20_01425 ENOG4106H6R UPF0380 protein CEQ20_01430 ENOG4108XS9 dna repair protein CEQ20_01475 ENOG4108KU3 Integrase CEQ20_01490 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase CEQ20_01495 ENOG4108HPI phosphatidate Cytidylyltransferase CEQ20_01505 ENOG4105E8V Alpha Beta Hydrolase Fold protein CEQ20_01510 ENOG41077RS Phosphatase CEQ20_01525 ENOG4105EQ2 LysR family Transcriptional regulator CEQ20_01530 ENOG4107SET aldo keto reductase CEQ20_01545 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CEQ20_01560 ENOG4105FE9 pseudouridine synthase CEQ20_01565 ENOG4105EZE Cupin 4 family protein CEQ20_01595 ENOG4108WC9 type VI secretion system effector, hcp1 family CEQ20_01610 ENOG4105HVQ Regulatory factor of maltose metabolism CEQ20_01615 ENOG4108JQB penicillin-binding protein 1C CEQ20_01620 ENOG4105DN3 alpha-2-macroglobulin domain protein CEQ20_01635 ENOG4105C26 Dehydrogenase CEQ20_01640 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) CEQ20_01650 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CEQ20_01655 ENOG4105C2J ABC transporter CEQ20_01660 ENOG4105CNN ABC, transporter CEQ20_01665 ENOG4105CK5 oxidoreductase CEQ20_01670 ENOG4105EDK PfkB domain protein CEQ20_01680 ENOG4105DH8 myo-inositol catabolism CEQ20_01690 ENOG4108JJ7 ABC transporter CEQ20_01715 ENOG4108N8T regulatoR CEQ20_01725 ENOG4105VEQ Cold shock protein CEQ20_01730 ENOG4107Z6W Protein CrcB homolog CEQ20_01735 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) CEQ20_01760 ENOG4105DZ1 carboxypeptidase CEQ20_01765 ENOG4105K6T rare lipoprotein A CEQ20_01770 ENOG4105CNI cell division protein FtsW CEQ20_01775 ENOG4105CJN penicillin-binding protein CEQ20_01785 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) CEQ20_01795 ENOG4105DJF DNA polymerase III, delta' subunit CEQ20_01810 ENOG4107PAI alpha helical protein CEQ20_01815 ENOG4105CDA abc transporter atp-binding protein CEQ20_01820 ENOG4105DRP amino acid AbC transporter CEQ20_01825 ENOG4105EAD ABC transporter CEQ20_01830 ENOG4107RP9 extracellular solute-binding protein, family 3 CEQ20_01835 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) CEQ20_01840 ENOG4108JU5 Magnesium and cobalt efflux protein CEQ20_01850 ENOG4105C9A Phoh family CEQ20_01860 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CEQ20_01900 ENOG4105CAQ asparagine synthetase CEQ20_01905 ENOG4105D4U had-superfamily hydrolase, subfamily iia CEQ20_01910 ENOG4105E2R ROK family CEQ20_01915 ENOG4105CE4 GlcNAc 6-P deacetylase CEQ20_01925 ENOG4105CI1 PTS System CEQ20_01930 ENOG4108RS6 transposase CEQ20_01950 ENOG41090R7 Ferric uptake CEQ20_01955 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) CEQ20_01965 ENOG4105NNH LexA regulated protein CEQ20_01970 ENOG4105EV9 Alpha Beta Hydrolase CEQ20_01990 ENOG4105DFP Integrase CEQ20_02005 ENOG4105H5P transposase CEQ20_02010 ENOG4108P8R CEQ20_02015 ENOG410679B prophage CP4-57 regulatory protein alpA CEQ20_02045 ENOG4108NEV two component transcriptional regulator, LytTR family CEQ20_02060 ENOG4105DFP Integrase CEQ20_02075 ENOG4108Z1B Cyclase dehydrase CEQ20_02085 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CEQ20_02090 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) CEQ20_02095 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) CEQ20_02105 ENOG4105BZN citrate synthase CEQ20_02110 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit CEQ20_02115 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein CEQ20_02125 ENOG4105E33 succinate dehydrogenase CEQ20_02130 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 CEQ20_02135 ENOG4105C7S Dehydrogenase CEQ20_02145 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha CEQ20_02150 ENOG4105C4M (Ubiquinol oxidase) subunit I CEQ20_02155 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii CEQ20_02165 ENOG4105KJB cyd operon protein YbgE CEQ20_02170 ENOG4107YD3 Thioesterase CEQ20_02175 ENOG4105E02 MotA TolQ exbB proton channel CEQ20_02180 ENOG4105M8F Biopolymer transport protein exbD tolR CEQ20_02185 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CEQ20_02185 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA CEQ20_02195 ENOG4105KCK Peptidoglycan-associated lipoprotein CEQ20_02200 ENOG4105UFD tol-pal system protein YbgF CEQ20_02240 ENOG4106Z1T Nicotinamide Mononucleotide Transporter CEQ20_02245 ENOG4105PGM cation diffusion facilitator family transporter CEQ20_02255 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CEQ20_02270 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) CEQ20_02280 ENOG4105F0Z galactose-1-phosphate uridylyltransferase CEQ20_02285 ENOG4105CMR udp-glucose 4-epimerase CEQ20_02295 ENOG4105DKW ABC transporter CEQ20_02300 ENOG4105F4R Transcriptional regulator mode CEQ20_02305 ENOG410680R Protein of unknown function (DUF2592) CEQ20_02310 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein CEQ20_02315 ENOG4105E0C molybdate abc transporter CEQ20_02325 ENOG4108K4B hydrolase CEQ20_02350 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) CEQ20_02355 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CEQ20_02360 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) CEQ20_02370 ENOG4105VYA Uncharacterized conserved protein (DUF2132) CEQ20_02375 ENOG4105CHW UPF0052 protein CEQ20_02380 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) CEQ20_02390 ENOG4105M00 molybdopterin converting factor, subunit 1 CEQ20_02395 ENOG4108ZAF Molybdopterin CEQ20_02400 ENOG4105HFZ Membrane CEQ20_02420 ENOG4105C94 Transporter CEQ20_02425 ENOG4105CN8 Transcriptional regulator CEQ20_02435 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) CEQ20_02440 ENOG4105EAA nucleoside CEQ20_02450 ENOG4105BZU Histidine kinase CEQ20_02460 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CEQ20_02480 ENOG4107QWP ABC-2 type transporter CEQ20_02485 ENOG4107QWP ABC-2 type transporter CEQ20_02490 ENOG4105CJ1 ABC, transporter CEQ20_02500 ENOG4107MVR Transcriptional regulator CEQ20_02505 ENOG4105C1J atp-dependent rna helicase CEQ20_02555 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) CEQ20_02565 ENOG41061WM D-Alanyl-D-Alanine CEQ20_02570 ENOG4105CXG d-lactate dehydrogenase CEQ20_02580 ENOG4105N1F Hnh endonuclease CEQ20_02590 ENOG4105Y3U Transglycosylase-associated protein CEQ20_02600 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein CEQ20_02615 ENOG4108W15 Protein of unknown function (DUF1456) CEQ20_02625 ENOG4105C32 Amino acid ABC transporter (Permease) CEQ20_02630 ENOG4105CNN ABC, transporter CEQ20_02635 ENOG4108JJB ABC transporter CEQ20_02640 ENOG4108IV0 ABC, transporter CEQ20_02655 ENOG4105KHC sulfurtransferase CEQ20_02660 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system CEQ20_02665 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component CEQ20_02670 ENOG4108IJ8 ABC transporter CEQ20_02675 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component CEQ20_02680 ENOG4105D5Q Arginine ornithine antiporter CEQ20_02685 ENOG4105CXN decarboxylase CEQ20_02695 ENOG4105FDR Membrane CEQ20_02710 ENOG4105DVT helicase CEQ20_02715 ENOG4105CH6 catalase CEQ20_02720 ENOG4108UII YfaZ family CEQ20_02725 ENOG4105E0U tyrosine-specific transport protein CEQ20_02740 ENOG4105XPH Ferredoxin CEQ20_02745 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CEQ20_02750 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CEQ20_02760 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CEQ20_02765 ENOG4105BZU Histidine kinase CEQ20_02770 ENOG41068CG regulatoR CEQ20_02775 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC CEQ20_02780 ENOG4106UW1 Major Facilitator superfamily CEQ20_02785 ENOG4105FCK Membrane CEQ20_02800 ENOG4107R6D beta-lactam binding protein AmpH CEQ20_02805 ENOG4105CT4 transporter CEQ20_02815 ENOG4105C8Q Methyl-accepting chemotaxis CEQ20_02830 ENOG4105Y50 Virulence Protein CEQ20_02840 ENOG4105HRS Antitermination protein CEQ20_02845 ENOG4105G63 Type III effector Hrp-dependent CEQ20_02855 ENOG4105MVE transcriptional regulator CEQ20_02860 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) CEQ20_02880 ENOG4105TKZ Tail Sheath CEQ20_02920 ENOG4108T86 baseplate J family protein CEQ20_02935 ENOG4108Q3X Transcriptional regulator CEQ20_02940 ENOG4105CS2 ec 3.2.1.21 CEQ20_02990 ENOG4105E68 Sulfatase CEQ20_02995 ENOG4105PAN UPF0352 protein CEQ20_03005 ENOG4108RS6 transposase CEQ20_03020 ENOG4105CFI type iii restriction protein res subunit CEQ20_03025 ENOG4105I08 Pseudouridine synthase CEQ20_03030 ENOG4105C2C drug resistance transporter, Bcr CflA CEQ20_03035 ENOG4105HG6 CEQ20_03040 ENOG4108JQ5 ABC transporter CEQ20_03045 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component CEQ20_03050 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component CEQ20_03055 ENOG4105E43 Extracellular solute-binding protein, family 5 CEQ20_03060 ENOG4105CXC rtn protein CEQ20_03065 ENOG4107TT5 NLP P60 protein CEQ20_03070 ENOG41076MN Phosphoesterase, PA-phosphatase related CEQ20_03075 ENOG4105CKI cobalamin synthesis protein CEQ20_03085 ENOG4107YCY Transcriptional regulator CEQ20_03090 ENOG4105DEI Mannitol dehydrogenase CEQ20_03110 ENOG4105KRS Proteinase inhibitor CEQ20_03115 ENOG4105CHR reductase CEQ20_03130 ENOG4105C26 Dehydrogenase CEQ20_03140 ENOG4105E66 phosphoriboisomerase A CEQ20_03150 ENOG4105C2J ABC transporter CEQ20_03155 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane CEQ20_03165 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein CEQ20_03170 ENOG4105DE4 1-phosphofructokinase CEQ20_03175 ENOG4105DM4 PTS System CEQ20_03180 ENOG4108SGD regulatory protein CEQ20_03195 ENOG4108UIF Chaperone CEQ20_03200 ENOG4108D1K outer membrane usher protein CEQ20_03210 ENOG4105HMI Membrane CEQ20_03215 ENOG4105DUM transcriptional regulator, lysR family CEQ20_03220 ENOG4108IQI permease CEQ20_03230 ENOG4105EHG Permease protein CEQ20_03240 ENOG4105D05 Receptor CEQ20_03245 ENOG4108TGY Glutathione S-transferase CEQ20_03260 ENOG4105D01 (LipO)protein CEQ20_03270 ENOG4108UMI ABC transporter, permease CEQ20_03275 ENOG4105DZ1 carboxypeptidase CEQ20_03280 ENOG4105C44 Serine transporter CEQ20_03285 ENOG4107FB0 transcriptional regulator DeoR family CEQ20_03290 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CEQ20_03295 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase CEQ20_03310 ENOG4105D0C transport protein CEQ20_03315 ENOG41090BQ Glutaredoxin CEQ20_03325 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress CEQ20_03335 ENOG4108RMJ sensory transduction regulator CEQ20_03340 ENOG4107RUE extracellular solute-binding protein family 1 CEQ20_03345 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CEQ20_03350 ENOG4105F38 ABC transporter, permease CEQ20_03355 ENOG4105D38 putrescine abc transporter CEQ20_03360 ENOG4105RBQ inner membrane protein ybjO CEQ20_03370 ENOG4106TNF Periplasmic binding protein CEQ20_03385 ENOG4108I9K permease protein CEQ20_03390 ENOG4105E0A ABC, transporter CEQ20_03395 ENOG410642S Nicotianamine synthase protein CEQ20_03400 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) CEQ20_03405 ENOG4108I0N Transporter, RarD family, DMT superfamily protein CEQ20_03410 ENOG4105DMR ABC, transporter CEQ20_03415 ENOG4105GBT ABC transporter CEQ20_03420 ENOG4106PMH Extracellular solute-binding protein family 3 CEQ20_03425 ENOG4105E5Z arginine transporter ATP-binding subunit CEQ20_03430 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) CEQ20_03435 ENOG41064MM (LipO)protein CEQ20_03440 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CEQ20_03445 ENOG4105CGD Nad-dependent epimerase dehydratase CEQ20_03450 ENOG4105C5W Aldolase CEQ20_03455 ENOG4105C7K acetolactate synthase CEQ20_03460 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CEQ20_03470 ENOG4105DWU Membrane CEQ20_03475 ENOG4105CPB ATP-dependent endonuclease of the OLD family CEQ20_03480 ENOG4108MJ5 VirK protein CEQ20_03485 ENOG4105DJY efflux transporter, rnd family, mfp subunit CEQ20_03495 ENOG4105VEQ Cold shock protein CEQ20_03510 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEQ20_03515 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) CEQ20_03525 ENOG4108JJ8 (ABC) transporter CEQ20_03530 ENOG4108JJ9 ABC, transporter CEQ20_03535 ENOG4105C3M thioredoxin reductase CEQ20_03540 ENOG4105EW9 transcriptional regulator AsnC family CEQ20_03545 ENOG4105CNU cell division protein FtsK CEQ20_03555 ENOG4105D1H recombination factor protein RarA CEQ20_03565 ENOG4108ISG Major Facilitator CEQ20_03570 ENOG4105F1A Pyruvate formate-lyase CEQ20_03580 ENOG4105C6N Formate acetyltransferase CEQ20_03585 ENOG4105TMB Formate nitrite transporter CEQ20_03590 ENOG4105DDY UPF0142 protein ycaO CEQ20_03595 ENOG4105HDK L-asparaginase CEQ20_03625 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) CEQ20_03640 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 CEQ20_03665 ENOG4105VEQ Cold shock protein CEQ20_03670 ENOG4105W49 UPF0434 protein CEQ20_03685 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups CEQ20_03695 ENOG4106371 Methyltransferase CEQ20_03700 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) CEQ20_03705 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) CEQ20_03715 ENOG4105DIT ErfK YbiS YcfS YnhG family protein CEQ20_03720 ENOG4105EAQ (twin-arginine translocation) pathway signal CEQ20_03725 ENOG4105C5X domain protein CEQ20_03735 ENOG4105CGF Aromatic amino acid aminotransferase CEQ20_03755 ENOG4105CD8 aminopeptidase N CEQ20_03765 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) CEQ20_03770 ENOG4105QVC MOSC domain-containing protein CEQ20_03780 ENOG4105C5H ABC transporter CEQ20_03785 ENOG4105F1S paraquat-inducible protein a CEQ20_03790 ENOG4105DY2 Paraquat-inducible protein b CEQ20_03795 ENOG4108Q2G (LipO)protein CEQ20_03805 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) CEQ20_03810 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CEQ20_03825 ENOG4105DAN ATP-dependent protease CEQ20_03835 ENOG4105UYK outer membrane protein a CEQ20_03845 ENOG4108RZ1 DNA transformation protein CEQ20_03850 ENOG4105EM2 membrane CEQ20_03855 ENOG410901E Membrane CEQ20_03860 ENOG41088T4 Helicase IV CEQ20_03870 ENOG4108Q67 UPF0319 protein CEQ20_03875 ENOG4105K4P CoA-binding domain protein CEQ20_03890 ENOG4108I1J Integrase CEQ20_03940 ENOG4105RWQ Protein of unknown function (DUF1364) CEQ20_03945 ENOG4105HRS Antitermination protein CEQ20_03950 ENOG4105NI8 Cytosine-specific methyltransferase CEQ20_04065 ENOG4105Y50 Virulence Protein CEQ20_04070 ENOG4108HMX isocitrate dehydrogenase (NADP) CEQ20_04085 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor CEQ20_04090 ENOG4105ECR NmrA family CEQ20_04095 ENOG4105KVH Transcriptional regulator CEQ20_04100 ENOG4105D6F Phosphatase CEQ20_04105 ENOG41061EV selenium-binding protein YdfZ CEQ20_04115 ENOG4108XM1 transcriptional regulator AsnC family CEQ20_04120 ENOG4105GSJ Inner membrane protein ylaC CEQ20_04135 ENOG4105VEQ Cold shock protein CEQ20_04145 ENOG4105C8Q Methyl-accepting chemotaxis CEQ20_04150 ENOG4105KT7 mgtC SapB transporter CEQ20_04155 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic CEQ20_04165 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region CEQ20_04170 ENOG4107RD7 Flagellar Motor Protein, MotA CEQ20_04175 ENOG4105ER2 Ompa motb domain protein CEQ20_04180 ENOG4105CBS Chea signal transduction histidine kinase CEQ20_04185 ENOG4108V3W Chemotaxis protein, CheW CEQ20_04200 ENOG4105C8Q Methyl-accepting chemotaxis CEQ20_04205 ENOG4105C8Q Methyl-accepting chemotaxis CEQ20_04210 ENOG4105BZU Histidine kinase CEQ20_04220 ENOG4108VYJ response regulator receiver protein CEQ20_04225 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) CEQ20_04235 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CEQ20_04250 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CEQ20_04285 ENOG4105WT8 Protein of unknown function (DUF1480) CEQ20_04300 ENOG4105GQR Chaperone CEQ20_04320 ENOG4105DY2 Paraquat-inducible protein b CEQ20_04325 ENOG4105H2K paraquat-inducible protein a CEQ20_04330 ENOG4108ZGC gaf domain protein CEQ20_04340 ENOG4105CN1 protease CEQ20_04355 ENOG4105H8W Fimbrial protein CEQ20_04360 ENOG4108VEV chaperone CEQ20_04375 ENOG4108VEV chaperone CEQ20_04380 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEQ20_04385 ENOG4105CAZ oligogalacturonide lyase CEQ20_04395 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CEQ20_04400 ENOG4108ETY sodium dicarboxylate symporter CEQ20_04405 ENOG4107K5X Membrane-bound metal-dependent hydrolase CEQ20_04410 ENOG4108PU9 oligogalacturonate-specific porin CEQ20_04415 ENOG4105WEM extracellular solute-binding protein CEQ20_04425 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component CEQ20_04430 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component CEQ20_04435 ENOG41061NF Pectate lyase CEQ20_04440 ENOG4105CHR reductase CEQ20_04450 ENOG4105M5J Cupin 2, conserved barrel domain protein CEQ20_04460 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 CEQ20_04465 ENOG4107PN8 YfeABCD locus regulator CEQ20_04470 ENOG4105FGM Fructosamine kinase CEQ20_04480 ENOG4105CC5 ABC transporter CEQ20_04485 ENOG4105CC5 ABC transporter CEQ20_04490 ENOG4105DIK (ABC) transporter CEQ20_04495 ENOG4105DSE periplasmic solute binding protein CEQ20_04520 ENOG41087WU CEQ20_04555 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) CEQ20_04560 ENOG4108RS6 transposase CEQ20_04580 ENOG4108V06 Glutathione peroxidase CEQ20_04585 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) CEQ20_04630 ENOG4108QBX (LipO)protein CEQ20_04645 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) CEQ20_04655 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) CEQ20_04665 ENOG4105IPI Membrane CEQ20_04670 ENOG4105CQB FAD linked oxidase domain protein CEQ20_04675 ENOG4105KA0 thioesterase Superfamily protein CEQ20_04685 ENOG4108Z4V iron-sulfur cluster assembly CEQ20_04690 ENOG4105DIW FeS assembly protein SUFB CEQ20_04695 ENOG4105C3K feS assembly ATPase SufC CEQ20_04700 ENOG4105JRK feS assembly protein SufD CEQ20_04715 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein CEQ20_04720 ENOG4105KMX major outer membrane lipoprotein CEQ20_04725 ENOG4105CA9 Pyruvate kinase CEQ20_04750 ENOG4108R6K riboflavin synthase, subunit alpha CEQ20_04755 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase CEQ20_04760 ENOG4105CZQ inner membrane transport protein YdhC CEQ20_04765 ENOG4105F52 Transcriptional regulator CEQ20_04780 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CEQ20_04785 ENOG4105K4H Nlp p60 protein CEQ20_04795 ENOG4105M2J Glutaredoxin CEQ20_04810 ENOG4108UYE Lactoylglutathione lyase CEQ20_04820 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CEQ20_04825 ENOG4108WUH Transcriptional regulator, TetR family CEQ20_04830 ENOG4105DIJ Phosphoethanolamine transferase CEQ20_04835 ENOG4105XZD Fe-S protein CEQ20_04840 ENOG4107RGM aldo keto reductase CEQ20_04855 ENOG4108XTF Outer Membrane Lipoprotein CEQ20_04865 ENOG410642K Lysozyme inhibitor CEQ20_04885 ENOG4108K3A Glutathione S-transferase CEQ20_04895 ENOG4108ZR5 Conserved Protein CEQ20_04900 ENOG41069YE inner membrane protein yohC CEQ20_04905 ENOG4105DUX Transporter CEQ20_04910 ENOG4105Q4T oxidoreductase CEQ20_04915 ENOG4108JQ2 peptide transport system atp-binding protein CEQ20_04920 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein CEQ20_04925 ENOG4108EU3 peptide transport system, permease CEQ20_04930 ENOG4108I5W peptide transport system, permease protein CEQ20_04935 ENOG4108HIY periplasmic CEQ20_04945 ENOG4105E51 psp operon transcriptional activator CEQ20_04950 ENOG41087YS Phage shock protein A CEQ20_04955 ENOG4105YYT phage shock protein B CEQ20_04960 ENOG4105FM1 phage shock protein C CEQ20_04970 ENOG4105CM6 amino acid regulated cytosolic protein CEQ20_04995 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) CEQ20_05000 ENOG4107S8C mandelate racemase muconate lactonizing CEQ20_05005 ENOG4105KXI murein peptide amidase A CEQ20_05010 ENOG4107QSI ABC, transporter CEQ20_05045 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) CEQ20_05055 ENOG4105KT7 mgtC SapB transporter CEQ20_05065 ENOG41090X5 Heat shock protein hslJ CEQ20_05070 ENOG4105C5I Dehydrogenase CEQ20_05075 ENOG4107H52 Dicarboxylate transport CEQ20_05080 ENOG410689M (LipO)protein CEQ20_05085 ENOG4105WXT Conserved Protein CEQ20_05090 ENOG4105DEI Mannitol dehydrogenase CEQ20_05095 ENOG4105DKT Transcriptional regulator CEQ20_05105 ENOG4105CQ7 ATP-dependent helicase CEQ20_05120 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap CEQ20_05135 ENOG4105DS1 cytochrome b561 CEQ20_05160 ENOG4105CTD carboxy-peptidase CEQ20_05165 ENOG4105JJR Histidine kinase CEQ20_05170 ENOG4107EXC regulatoR CEQ20_05180 ENOG4105D5Q Arginine ornithine antiporter CEQ20_05185 ENOG4105C5D exported protein CEQ20_05195 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CEQ20_05200 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) CEQ20_05210 ENOG4105Q9Y Universal stress protein CEQ20_05215 ENOG4105DS0 Transcriptional regulator, Crp Fnr family CEQ20_05220 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CEQ20_05235 ENOG4105PAD Hydrolase CEQ20_05240 ENOG4105M71 acetolactate synthase 1 regulatory subunit CEQ20_05245 ENOG4105C7K acetolactate synthase CEQ20_05275 ENOG4105FYV Amp nucleosidase CEQ20_05285 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component CEQ20_05290 ENOG4107UWC ABC, transporter CEQ20_05300 ENOG4105C2J ABC transporter CEQ20_05305 ENOG4105CNN ABC, transporter CEQ20_05310 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CEQ20_05320 ENOG41060NJ transcriptional regulator CEQ20_05325 ENOG4105DFD Na H antiporter CEQ20_05330 ENOG4105C87 Aminotransferase class I and II CEQ20_05340 ENOG4105DWP Membrane CEQ20_05355 ENOG4105EMU Dehydrogenase CEQ20_05365 ENOG4105KBG Protein of unknown function (DUF1161) CEQ20_05370 ENOG4105CMQ Chloride channel CEQ20_05375 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) CEQ20_05380 ENOG4105DAG ROK family CEQ20_05385 ENOG4106NZI LysR family Transcriptional regulator CEQ20_05390 ENOG4105D94 Major Facilitator Superfamily CEQ20_05395 ENOG4105KR1 Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence (By similarity) CEQ20_05400 ENOG4105C9Q fumarate hydratase class II CEQ20_05405 ENOG4105EIP mannose-6-phosphate isomerase CEQ20_05410 ENOG4106J39 exported protein CEQ20_05420 ENOG4105DHU Bile acid CEQ20_05425 ENOG4105D9R oxidoreductase CEQ20_05435 ENOG4105CNN ABC, transporter CEQ20_05445 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator CEQ20_05460 ENOG4108JJA ABC, transporter CEQ20_05475 ENOG4105M9B inner membrane protein ydgK CEQ20_05495 ENOG4105UEI Transcriptional Regulator AraC Family CEQ20_05505 ENOG4108UQQ Electron transport complex CEQ20_05515 ENOG4105CSM endonuclease III CEQ20_05520 ENOG4105EXW epimerase dehydratase CEQ20_05525 ENOG4105CSP Major Facilitator Superfamily CEQ20_05535 ENOG4105D22 carbon starvation protein CEQ20_05540 ENOG4105VCD cytoplasmic protein CEQ20_05545 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) CEQ20_05555 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase CEQ20_05560 ENOG41061RM osmotically inducible lipoprotein CEQ20_05565 ENOG4108ZJT translation initiation factor, Sui1 CEQ20_05580 ENOG4105CFV Tetratricopeptide repeat protein CEQ20_05585 ENOG4105Q4A inner membrane protein yciS CEQ20_05590 ENOG4105EYK Phosphatidylglycerophosphatase B CEQ20_05595 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) CEQ20_05600 ENOG4107QM5 aconitate hydratase CEQ20_05615 ENOG4107R11 Transcriptional regulator CEQ20_05620 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CEQ20_05630 ENOG4105RKX Protein of unknown function (DUF2498) CEQ20_05635 ENOG4105ERU peptidase CEQ20_05640 ENOG4105UBK short-chain dehydrogenase reductase CEQ20_05645 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase CEQ20_05650 ENOG4105FE9 pseudouridine synthase CEQ20_05655 ENOG4107RTD sua5 ycio yrdc ywlc family protein CEQ20_05660 ENOG4105DB7 PHP domain protein CEQ20_05680 ENOG4105DDQ anthranilate synthase CEQ20_05690 ENOG4105DK0 Indole-3-glycerol phosphate synthase CEQ20_05710 ENOG4105EIF outer membrane protein W CEQ20_05740 ENOG4105NAU thioesterase Superfamily protein CEQ20_05745 ENOG410822N TonB family CEQ20_05750 ENOG4105K9H YciI-like protein CEQ20_05765 ENOG4108T1M outer membrane protein x CEQ20_05790 ENOG4108JQ7 (ABC) transporter CEQ20_05795 ENOG4105C3U ABC transporter CEQ20_05800 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEQ20_05810 ENOG4107QSI ABC, transporter CEQ20_05815 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein CEQ20_05835 ENOG4107104 thymidine kinase CEQ20_05845 ENOG4105C6Y Udp-glucose 6-dehydrogenase CEQ20_05850 ENOG4105I93 response regulator CEQ20_05860 ENOG4105CIY formyltetrahydrofolate deformylase CEQ20_05890 ENOG4105SKE transcriptional Regulator LysR family CEQ20_05895 ENOG4105CGK Exodeoxyribonuclease III CEQ20_05900 ENOG4105M6F mutator MutT protein CEQ20_05905 ENOG4105MTM Protein of unknown function (DUF1496) CEQ20_05910 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) CEQ20_05920 ENOG41069NU Nitroreductase CEQ20_05925 ENOG4105D07 Signal peptide peptidase, SppA CEQ20_05930 ENOG4105HDK L-asparaginase CEQ20_05935 ENOG4108RWI nicotinamidase CEQ20_05940 ENOG4105VUT cytoplasmic protein CEQ20_05955 ENOG4105DSB aldose 1-epimerase CEQ20_05960 ENOG4105GNX MltA-interacting MipA family protein CEQ20_05970 ENOG4105CYN Serine protein kinase CEQ20_05985 ENOG4105HEI LysR family (Transcriptional regulator CEQ20_05990 ENOG4105EUB pirin domain protein CEQ20_05995 ENOG4105CNH Multidrug resistance protein MdtL CEQ20_06005 ENOG4105ED1 spovr family CEQ20_06040 ENOG4105C3J Cysteine desulfurase CEQ20_06055 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase CEQ20_06060 ENOG4105CVE Lytic murein transglycosylase CEQ20_06080 ENOG4107QMS site-determining protein CEQ20_06085 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) CEQ20_06105 ENOG4105CEY Amp-dependent synthetase and ligase CEQ20_06115 ENOG4105Y4Z Outer Membrane Lipoprotein CEQ20_06120 ENOG41072GX Peptidase M22 Glycoprotease CEQ20_06125 ENOG4105DVT helicase CEQ20_06130 ENOG4105M4H endoribonuclease L-psp CEQ20_06145 ENOG4108UHU Aldolase CEQ20_06155 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase CEQ20_06160 ENOG4106KNT transcriptional regulator CEQ20_06165 ENOG4105CA9 Pyruvate kinase CEQ20_06175 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase CEQ20_06180 ENOG4105DR5 peptidase CEQ20_06185 ENOG4105NXV High-affinity zinc uptake system protein CEQ20_06195 ENOG4105FAV ABC, transporter CEQ20_06225 ENOG4108TIT dATP pyrophosphohydrolase CEQ20_06235 ENOG41081XQ Conserved Protein CEQ20_06240 ENOG4105WJG Glutathione CEQ20_06260 ENOG4106ZCM YecM protein CEQ20_06285 ENOG4105CJR Integral membrane protein (MviN CEQ20_06300 ENOG4105D9U N-acetyltransferase CEQ20_06310 ENOG4105F3T (LipO)protein CEQ20_06315 ENOG4107XHZ cytoplasmic chaperone TorD family protein CEQ20_06330 ENOG4105E2R ROK family CEQ20_06335 ENOG4108QXE glycerophosphoryl diester phosphodiesterase CEQ20_06345 ENOG4105F38 ABC transporter, permease CEQ20_06375 ENOG4105CHH sulfate transporter CEQ20_06385 ENOG41063JG Transcriptional regulator CEQ20_06390 ENOG4108YY7 Invasion gene expression up-regulator SirB CEQ20_06395 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) CEQ20_06420 ENOG4105C5T Phosphoribosyl pyrophosphate synthase CEQ20_06425 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria CEQ20_06435 ENOG4105C3G gtp-binding protein CEQ20_06440 ENOG4105DFP Integrase CEQ20_06475 ENOG4105ENX hydrolase CEQ20_06485 ENOG4105GR3 Histidine kinase CEQ20_06535 ENOG4108WF3 methyltransferase CEQ20_06600 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase CEQ20_06605 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) CEQ20_06620 ENOG41090B9 response to stress CEQ20_06625 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) CEQ20_06630 ENOG4105CZE histidine utilization repressor CEQ20_06675 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CEQ20_06685 ENOG4105BZU Histidine kinase CEQ20_06690 ENOG4105EWV Sodium calcium exchanger membrane region CEQ20_06695 ENOG4105D5M phosphate starvation-inducible protein CEQ20_06710 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD CEQ20_06715 ENOG4105CND Glycosyl transferase, family 2 CEQ20_06720 ENOG4107BJW polysaccharide deacetylase CEQ20_06725 ENOG4108TUY outer membrane protein PgaA CEQ20_06730 ENOG4105H1N peptidase, M24 CEQ20_06750 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CEQ20_06760 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) CEQ20_06775 ENOG4107SJW iron permease, FTR1 CEQ20_06785 ENOG4105CSV Glutaminase CEQ20_06795 ENOG4105MVE transcriptional regulator CEQ20_06800 ENOG4105C85 amino acid CEQ20_06805 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family CEQ20_06810 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) CEQ20_06825 ENOG4107RGD Major Facilitator superfamily CEQ20_06850 ENOG4105DJG MaoC domain protein dehydratase CEQ20_06855 ENOG4105CYC Transferase CEQ20_06860 ENOG4108Q9V regulatoR CEQ20_06865 ENOG4105BZU Histidine kinase CEQ20_06880 ENOG4105CW0 outer membrane usher protein CEQ20_06890 ENOG4108MQF Chaperone CEQ20_06905 ENOG4108IJ9 (ABC) transporter CEQ20_06910 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component CEQ20_06925 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) CEQ20_06935 ENOG4105FDP GntR family transcriptional regulator CEQ20_07040 ENOG4105ZTC transcriptional activator, Ogr delta CEQ20_07070 ENOG4105WH1 Two component transcriptional regulator luxr family CEQ20_07075 ENOG4105XVG cytoplasmic protein CEQ20_07080 ENOG4105RA2 Membrane CEQ20_07095 ENOG4108T1M outer membrane protein x CEQ20_07105 ENOG4105C85 amino acid CEQ20_07135 ENOG4105CK7 Sodium proline symporter CEQ20_07145 ENOG4105C26 Dehydrogenase CEQ20_07160 ENOG4105CDA abc transporter atp-binding protein CEQ20_07165 ENOG4105E5Q amino acid AbC transporter CEQ20_07170 ENOG4105EAB amino acid AbC transporter CEQ20_07180 ENOG4108M9K flagella biosynthesis protein FliZ CEQ20_07185 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ20_07190 ENOG4105I03 Flagellin CEQ20_07195 ENOG4105DTS flagellar hook-associated CEQ20_07200 ENOG4105MQ3 flagellar protein FliS CEQ20_07210 ENOG4105DHT Metal Dependent Phosphohydrolase CEQ20_07235 ENOG4105VQ0 flagellar hook-basal body complex protein fliE CEQ20_07240 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CEQ20_07245 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CEQ20_07250 ENOG41090PJ Flagellar assembly protein CEQ20_07255 ENOG4108JIR Flagellum-specific ATP synthase CEQ20_07260 ENOG4105GSA Flagellar export protein flij CEQ20_07265 ENOG4105WF4 Flagellar hook-length control protein CEQ20_07270 ENOG4107ZI8 flagellar basal body-associated protein flil CEQ20_07275 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) CEQ20_07280 ENOG4105DD5 Flagellar motor switch protein CEQ20_07290 ENOG4105CN7 Flagellar biosynthetic protein FliP CEQ20_07295 ENOG4105VS8 Flagellar biosynthetic protein fliq CEQ20_07300 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CEQ20_07310 ENOG4108MGF sugar kinase CEQ20_07315 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane CEQ20_07320 ENOG4105C2J ABC transporter CEQ20_07330 ENOG4105CNN ABC, transporter CEQ20_07340 ENOG4105DKT Transcriptional regulator CEQ20_07345 ENOG4105DTJ flagellar hook-associated protein CEQ20_07350 ENOG4105E1Q flagellar hook-associated protein CEQ20_07355 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj CEQ20_07370 ENOG4105CGA flagellar basal-body rod protein FlgG CEQ20_07375 ENOG4108KPB Flagellar basal-body rod protein FlgF CEQ20_07380 ENOG4105BZE flagellar hook protein, FlgE CEQ20_07385 ENOG4105W00 Flagellar hook capping protein CEQ20_07390 ENOG4108ZC9 flagellar basal-body rod protein flgc CEQ20_07395 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CEQ20_07400 ENOG4105CKS Flagella basal body P-ring formation protein flgA CEQ20_07405 ENOG4105M9M anti-sigma28 factor FlgM CEQ20_07410 ENOG4105QVD Flagella synthesis protein FlgN CEQ20_07420 ENOG4105W13 flagellar protein CEQ20_07425 ENOG4105D7B Flagellar biosynthesis protein flha CEQ20_07430 ENOG4105D00 flagellar biosynthetic protein flhB CEQ20_07450 ENOG4105NKT exported protein CEQ20_07460 ENOG4105FXM Copper resistance protein CEQ20_07465 ENOG41090A1 ferritin CEQ20_07470 ENOG4105MPK DNA polymerase III subunit theta CEQ20_07480 ENOG4105CUG Oligopeptidase b CEQ20_07495 ENOG4105X2V dna damage-inducible protein CEQ20_07500 ENOG4105C1J atp-dependent rna helicase CEQ20_07515 ENOG4105CRQ synthase (Component I) CEQ20_07525 ENOG4105EJQ L-serine dehydratase CEQ20_07530 ENOG4107UWN reductase CEQ20_07535 ENOG4105EFA 4-hydroxyphenylacetate CEQ20_07560 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase CEQ20_07565 ENOG4105C26 Dehydrogenase CEQ20_07580 ENOG4108V8F Transcriptional regulator, MarR family CEQ20_07585 ENOG4105EE5 Membrane protein terC CEQ20_07590 ENOG4108EQA pts system CEQ20_07595 ENOG4105ETZ PTS System CEQ20_07600 ENOG4105F3R pts system mannose fructose sorbose family iid CEQ20_07620 ENOG4105BZU Histidine kinase CEQ20_07630 ENOG4105DHI Methyltransferase CEQ20_07635 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase CEQ20_07640 ENOG4105VEQ Cold shock protein CEQ20_07645 ENOG410610J Protein of unknown function (DUF2627) CEQ20_07660 ENOG4105C85 amino acid CEQ20_07680 ENOG41064PC CEQ20_07695 ENOG4105N4N Protein of unknown function (DUF2766) CEQ20_07715 ENOG4105BZ1 (ABC) transporter CEQ20_07750 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) CEQ20_07765 ENOG4108TSE Transferase CEQ20_07770 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit CEQ20_07780 ENOG4105CG6 trap dicarboxylate transporter dctm subunit CEQ20_07785 ENOG4108KX4 response regulator CEQ20_07795 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme CEQ20_07815 ENOG4105UQX Mate efflux family protein CEQ20_07835 ENOG4105DIA mandelate racemase muconate lactonizing CEQ20_07845 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr CEQ20_07850 ENOG4105KIR Thiol-disulfide oxidoreductase dcc CEQ20_07855 ENOG4105CSP Major Facilitator Superfamily CEQ20_07865 ENOG4105TNG K13735 adhesin invasin CEQ20_07880 ENOG4105CJB Exodeoxyribonuclease I CEQ20_07890 ENOG4105CUB amino acid CEQ20_07900 ENOG4107SCQ Iron-containing alcohol dehydrogenase CEQ20_07905 ENOG4105C2J ABC transporter CEQ20_07910 ENOG4105CNN ABC, transporter CEQ20_07930 ENOG4108535 NAD dependent epimerase/dehydratase family CEQ20_07945 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) CEQ20_07960 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) CEQ20_07975 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase CEQ20_07980 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) CEQ20_07985 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CEQ20_07990 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase CEQ20_07995 ENOG4105DUU IucA IucC family protein CEQ20_08000 ENOG4105CNM Receptor CEQ20_08005 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) CEQ20_08010 ENOG4105DQ5 transport system permease protein CEQ20_08015 ENOG4105TVJ transport system, permease CEQ20_08020 ENOG4105E0A ABC, transporter CEQ20_08025 ENOG4105DUU IucA IucC family protein CEQ20_08035 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) CEQ20_08040 ENOG4105DY8 decarboxylase CEQ20_08045 ENOG4108819 ferric iron reductase CEQ20_08050 ENOG4105EE5 Membrane protein terC CEQ20_08055 ENOG4108GAE asmA family CEQ20_08070 ENOG4105D1F ATP-binding protein CEQ20_08095 ENOG4105E5W Transporter CEQ20_08105 ENOG41067MG lrgb family CEQ20_08120 ENOG4107GZ4 SanA protein CEQ20_08125 ENOG4108HWV )-transporter CEQ20_08140 ENOG4105DHF Membrane CEQ20_08150 ENOG4105CBP Major Facilitator CEQ20_08155 ENOG4105EGI Transcriptional regulator CEQ20_08180 ENOG4105ENT Efflux transporter rnd family, mfp subunit CEQ20_08185 ENOG4105C19 ABC transporter CEQ20_08195 ENOG4105CVM Molybdenum cofactor synthesis domain protein CEQ20_08200 ENOG4105D06 uba thif-type nad fad binding protein CEQ20_08210 ENOG4105C5H ABC transporter CEQ20_08305 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEQ20_08320 ENOG4105CDV Ompa motb domain protein CEQ20_08345 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CEQ20_08350 ENOG41062T2 Acyl carrier protein CEQ20_08360 ENOG4105CHR reductase CEQ20_08365 ENOG4108KQ6 Enoyl-CoA hydratase CEQ20_08375 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase CEQ20_08380 ENOG4105CHR reductase CEQ20_08385 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CEQ20_08390 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) CEQ20_08425 ENOG4108Z0T Part of a sulfur-relay system (By similarity) CEQ20_08495 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 CEQ20_08525 ENOG4105CDU Replicative dna helicase CEQ20_08640 ENOG4108I1J Integrase CEQ20_08645 ENOG4108HMX isocitrate dehydrogenase (NADP) CEQ20_08650 ENOG4108R99 pseudouridine synthase CEQ20_08670 ENOG4107QTF adenylosuccinate lyase CEQ20_08680 ENOG4105XJC Two component transcriptional regulator (Winged helix family CEQ20_08690 ENOG4105EZE Cupin 4 family protein CEQ20_08705 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) CEQ20_08720 ENOG4105D60 lipoprotein releasing system transmembrane protein CEQ20_08730 ENOG4105D60 lipoprotein releasing system transmembrane protein CEQ20_08735 ENOG4108JA2 transcriptioN-repair coupling factor CEQ20_08740 ENOG4107MBR 17 kDa surface antigen CEQ20_08755 ENOG4105CEP NADH dehydrogenase CEQ20_08780 ENOG41090DQ Lipoprotein CEQ20_08785 ENOG4105K59 histidine triad (HIT) protein CEQ20_08790 ENOG4105F9E Shikimate 5-dehydrogenase CEQ20_08795 ENOG4105CI1 PTS System CEQ20_08800 ENOG4105F8V Hydrolase, tatD family CEQ20_08805 ENOG4107QRG dna polymerase iii CEQ20_08815 ENOG4105HHA aminodeoxychorismate lyase CEQ20_08820 ENOG4105YAZ 4-amino-4-deoxychorismate lyase CEQ20_08825 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CEQ20_08835 ENOG4105CHR reductase CEQ20_08840 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase CEQ20_08855 ENOG4105VGS 50s ribosomal protein l32 CEQ20_08860 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein CEQ20_08870 ENOG4105EI2 Pseudouridine synthase CEQ20_08880 ENOG4107QQB Ribonuclease E CEQ20_08890 ENOG41067V3 Antibiotic biosynthesis monooxygenase CEQ20_08910 ENOG4105PVA Biofilm formation regulatory protein BssS CEQ20_08930 ENOG4105DSF transport protein CEQ20_08950 ENOG4105D1S lipid A biosynthesis CEQ20_08955 ENOG4105DUX Transporter CEQ20_08960 ENOG4105NAC (LipO)protein CEQ20_08965 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) CEQ20_08970 ENOG4105DJ9 glucan biosynthesis protein CEQ20_08975 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) CEQ20_09000 ENOG4107YC3 synthase CEQ20_09005 ENOG4105VJY transcriptional regulator CEQ20_09010 ENOG4105ETT transcriptional Regulator, LysR family CEQ20_09020 ENOG4105C54 Major Facilitator superfamily CEQ20_09030 ENOG4105CPC Aldo Keto reductase CEQ20_09035 ENOG4108Y1S CRISPR-associated protein, Csy4 family CEQ20_09040 ENOG4105M6W Crispr-associated protein, Csy3 family CEQ20_09045 ENOG4105DZX CRISPR-associated protein, Csy2 family CEQ20_09050 ENOG4105ENG CRISPR-associated protein, Csy1 family CEQ20_09055 ENOG4107IIZ CRISPR-associated helicase, Cas3 CEQ20_09060 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) CEQ20_09065 ENOG4105CUY Mechanosensitive ion channel CEQ20_09090 ENOG4105HY2 Glycosidase related protein CEQ20_09095 ENOG4105DRS transport system, permease CEQ20_09110 ENOG4105ETE Transcriptional regulator (LacI family CEQ20_09120 ENOG4108IJ9 (ABC) transporter CEQ20_09130 ENOG4105CKT filamentous hemagglutinin CEQ20_09155 ENOG4105CKT filamentous hemagglutinin CEQ20_09160 ENOG4105TIV Cryptic phage CTXphi transcriptional repressor RstR CEQ20_09170 ENOG4108RS6 transposase CEQ20_09190 ENOG4105D5K Hemolysin activator protein CEQ20_09195 ENOG4105E3J oxidoreductase CEQ20_09200 ENOG4105DVW rieske (2Fe-2S) CEQ20_09205 ENOG4105C94 Transporter CEQ20_09215 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CEQ20_09220 ENOG4105EJC lysr family transcriptional regulator CEQ20_09225 ENOG4105FKQ transcriptional regulator CEQ20_09230 ENOG4105CNN ABC, transporter CEQ20_09235 ENOG4105C2J ABC transporter CEQ20_09240 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CEQ20_09245 ENOG4105CPQ Dehydrogenase CEQ20_09265 ENOG4108T1M outer membrane protein x CEQ20_09295 ENOG4107R0W ABC transporter CEQ20_09300 ENOG4105E5Q amino acid AbC transporter CEQ20_09305 ENOG4105CDA abc transporter atp-binding protein CEQ20_09310 ENOG4107SDU Methyl-accepting chemotaxis CEQ20_09330 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction CEQ20_09340 ENOG4108MTB glycosyl transferase family CEQ20_09345 ENOG4105CEY Amp-dependent synthetase and ligase CEQ20_09355 ENOG4108IPT Naphthoate synthase CEQ20_09370 ENOG4105E4F Isochorismate synthase CEQ20_09380 ENOG4105TNS Conserved Protein CEQ20_09395 ENOG4105C01 Dihydroxy-acid dehydratase CEQ20_09415 ENOG4105C5I Dehydrogenase CEQ20_09420 ENOG4105K2J Transcriptional regulator CEQ20_09425 ENOG4105F32 YngK protein CEQ20_09430 ENOG4105CHR reductase CEQ20_09435 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CEQ20_09440 ENOG4108R66 Conserved Protein CEQ20_09455 ENOG4105C8S subunit m CEQ20_09460 ENOG4105D65 subunit l CEQ20_09470 ENOG4107UFS subunit j CEQ20_09485 ENOG4108IEH NADH dehydrogenase subunit g CEQ20_09490 ENOG4107QIZ NADH dehydrogenase CEQ20_09495 ENOG4105GKE subunit e CEQ20_09505 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) CEQ20_09515 ENOG4107NQ8 LysR family Transcriptional regulator CEQ20_09520 ENOG4105CHM Aminotransferase CEQ20_09535 ENOG4107QWE )-transporter CEQ20_09540 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 CEQ20_09565 ENOG4105C6K Malic enzyme CEQ20_09570 ENOG4107P2S Transcriptional regulator CEQ20_09585 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC CEQ20_09590 ENOG4105PTV Nudix Hydrolase CEQ20_09595 ENOG4108RE9 Phosphodiesterase CEQ20_09605 ENOG4105ECP epimerase CEQ20_09610 ENOG4108JEH abc transporter atp-binding protein CEQ20_09615 ENOG4106YG3 ABC transporter CEQ20_09620 ENOG4105DSP amino acid AbC transporter CEQ20_09625 ENOG4105E89 ABC transporter CEQ20_09630 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase CEQ20_09635 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase CEQ20_09640 ENOG4105E96 Colicin v production protein CEQ20_09645 ENOG4108S3P Sporulation domain protein CEQ20_09650 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase CEQ20_09660 ENOG4105DQR SNARE associated Golgi CEQ20_09670 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CEQ20_09685 ENOG410631K Membrane CEQ20_09690 ENOG4106WZ1 flagella biosynthesis regulator CEQ20_09705 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) CEQ20_09715 ENOG4105MH2 YfcL protein CEQ20_09720 ENOG4108BPE -transporting atpase CEQ20_09725 ENOG4105EJ9 Membrane CEQ20_09740 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) CEQ20_09750 ENOG4108BY2 phosphohistidine phosphatase CEQ20_09765 ENOG4105KZW UPF0381 protein CEQ20_09770 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation CEQ20_09775 ENOG410903C (LipO)protein CEQ20_09780 ENOG4105KWW Biogenesis protein CEQ20_09785 ENOG4105KWW Biogenesis protein CEQ20_09790 ENOG4107QX9 Thiol disulfide interChange protein CEQ20_09795 ENOG4105DA4 cytochrome c-type biogenesis protein CEQ20_09805 ENOG4105X3C heme exporter protein CEQ20_09810 ENOG41060IM Heme exporter protein CEQ20_09815 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) CEQ20_09835 ENOG4108V0P LemA family CEQ20_09845 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA CEQ20_09875 ENOG4105CS6 Rhs element vgr protein CEQ20_09920 ENOG4105CW0 outer membrane usher protein CEQ20_09925 ENOG4105GQR Chaperone CEQ20_09935 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEQ20_09985 ENOG4105CVE Lytic murein transglycosylase CEQ20_10010 ENOG4108WC9 type VI secretion system effector, hcp1 family CEQ20_10020 ENOG4107QY8 reductase CEQ20_10025 ENOG4105QAX Iron-sulfur CEQ20_10030 ENOG4107KGK dmso reductase anchor subunit CEQ20_10035 ENOG4108NEM leader-binding protein dmsD CEQ20_10045 ENOG4107Y60 (LipO)protein CEQ20_10055 ENOG4106B0W Curli production assembly transport component CsgG CEQ20_10065 ENOG4108VKM cytochrome b561 CEQ20_10070 ENOG4105CHM Aminotransferase CEQ20_10075 ENOG41072TH Protein of unknown function (DUF1479) CEQ20_10090 ENOG4105C5Q Transcriptional regulator CEQ20_10095 ENOG4105CPC Aldo Keto reductase CEQ20_10170 ENOG4105VRT cytoplasmic protein CEQ20_10185 ENOG4105EXN Sulfate transport protein CysZ CEQ20_10190 ENOG4105C6T cysteine synthase CEQ20_10195 ENOG4105KZ7 phosphocarrier protein hpr CEQ20_10205 ENOG4105C5Y PTS System CEQ20_10210 ENOG4105E0F Histidine kinase CEQ20_10215 ENOG4105E3W Two component transcriptional regulator (Winged helix family CEQ20_10220 ENOG4105DJY efflux transporter, rnd family, mfp subunit CEQ20_10235 ENOG4105E1V na solute symporter CEQ20_10245 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CEQ20_10250 ENOG4105C87 Aminotransferase class I and II CEQ20_10260 ENOG41062D9 Histidine kinase CEQ20_10265 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CEQ20_10275 ENOG4105C6T cysteine synthase CEQ20_10285 ENOG4105ECW sulfate abc transporter CEQ20_10290 ENOG4108I5D sulfate abc transporter CEQ20_10295 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein CEQ20_10300 ENOG4108RS6 transposase CEQ20_10315 ENOG4105QEK Transcriptional regulator CEQ20_10325 ENOG4108R66 Conserved Protein CEQ20_10350 ENOG4105EZR dyp-type peroxidase family protein CEQ20_10355 ENOG4105E7K (LipO)protein CEQ20_10360 ENOG4105H4F exported protein CEQ20_10395 ENOG4105C6K Malic enzyme CEQ20_10405 ENOG4105CUW cytochrome C-TYPE protein CEQ20_10410 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) CEQ20_10420 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase CEQ20_10425 ENOG4108ZNS ferredoxin-type protein NapF CEQ20_10430 ENOG4105WH1 Two component transcriptional regulator luxr family CEQ20_10440 ENOG4105BZS acriflavin resistance protein CEQ20_10450 ENOG4105S2T inner membrane protein YbcI CEQ20_10460 ENOG4105C4X radical SAM domain protein CEQ20_10465 ENOG4105ENH Sulfatase CEQ20_10475 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CEQ20_10480 ENOG4107Z33 ABC transporter, permease CEQ20_10485 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC CEQ20_10495 ENOG4105KUZ arsenate reductase CEQ20_10525 ENOG4105CGZ zinc metallopeptidase CEQ20_10535 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CEQ20_10545 ENOG4105RH4 Glycine cleavage system transcriptional repressor CEQ20_10550 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen CEQ20_10565 ENOG4105C02 permease CEQ20_10570 ENOG4105ERG peptidase m48, ste24p CEQ20_10575 ENOG4105K89 arsenate reductase CEQ20_10585 ENOG4105C2W permease CEQ20_10600 ENOG4108V3E phosphoribosylglycinamide formyltransferase CEQ20_10605 ENOG4108MK9 spermidine N(1)-acetyltransferase CEQ20_10620 ENOG4105E2Z phosphate ABC transporter (Permease CEQ20_10625 ENOG4105C8U phosphate abc transporter CEQ20_10630 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) CEQ20_10635 ENOG4105C9X ppx gppa phosphatase CEQ20_10645 ENOG4105CJW magnesium transporter CEQ20_10650 ENOG4105R8A Heat shock protein CEQ20_10655 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component CEQ20_10660 ENOG4105F38 ABC transporter, permease CEQ20_10670 ENOG4108JPW Aminotransferase CEQ20_10680 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) CEQ20_10705 ENOG4105EB3 Histidine kinase CEQ20_10710 ENOG4105E3W Two component transcriptional regulator (Winged helix family CEQ20_10715 ENOG4105KWI UPF0339 protein CEQ20_10720 ENOG4105CFP Peptidase U32 CEQ20_10735 ENOG4108ZGU inhibitor of vertebrate lysozyme CEQ20_10745 ENOG4105DWF phosphomethylpyrimidine kinase CEQ20_10765 ENOG4105DZR Type I site-specific deoxyribonuclease CEQ20_10825 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CEQ20_10830 ENOG4108YGG dna repair protein CEQ20_10855 ENOG4105HVQ Regulatory factor of maltose metabolism CEQ20_10870 ENOG4105CNU cell division protein FtsK CEQ20_10950 ENOG4108WC9 type VI secretion system effector, hcp1 family CEQ20_10960 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) CEQ20_10970 ENOG4105VPD cellular component movement CEQ20_10985 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) CEQ20_10990 ENOG4105N21 Membrane CEQ20_11045 ENOG4105YYA enhanced serine sensitivity protein SseB CEQ20_11055 ENOG4105WVQ Fe-S assembly protein IscX CEQ20_11060 ENOG4108ZIT Ferredoxin, 2FE-2S CEQ20_11085 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins CEQ20_11090 ENOG4105C3J Cysteine desulfurase CEQ20_11110 ENOG4105D7X high-affinity nickel-transporter CEQ20_11115 ENOG41065CD Exported protein CEQ20_11120 ENOG4108MN2 Stationary phase inducible protein CsiE CEQ20_11125 ENOG4105D8G Major Facilitator superfamily CEQ20_11145 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) CEQ20_11150 ENOG4108M21 CEQ20_11155 ENOG4108YZA Nitrogen regulatory protein pii CEQ20_11160 ENOG4105C4K Nad synthetase CEQ20_11165 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CEQ20_11170 ENOG4108SKK alpha helix protein CEQ20_11175 ENOG4107WP9 Histidine kinase CEQ20_11205 ENOG4108Z6B deaminase CEQ20_11210 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB CEQ20_11220 ENOG4106G6Q Transcriptional regulator CEQ20_11295 ENOG4105HRS Antitermination protein CEQ20_11375 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding CEQ20_11385 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) CEQ20_11405 ENOG4105C3F Signal peptidase i CEQ20_11420 ENOG4105WMJ Positive regulator of sigma E, RseC MucC CEQ20_11425 ENOG4105VQK sigma E regulatory protein, MucB RseB CEQ20_11430 ENOG41069PW sigma-e factor negative regulatory protein CEQ20_11440 ENOG4108IYU L-aspartate oxidase CEQ20_11450 ENOG4105C1J atp-dependent rna helicase CEQ20_11500 ENOG4107R7A Allophanate hydrolase subunit 2 CEQ20_11505 ENOG4105P4J Allophanate hydrolase, subunit 1 CEQ20_11510 ENOG4107QNR UPF0135 protein CEQ20_11515 ENOG4107RF4 Phosphodiesterase CEQ20_11520 ENOG4105CVP deoxyribo-dipyrimidine photolyase CEQ20_11525 ENOG4107SEY Conserved Protein CEQ20_11535 ENOG4105XIQ Protein of unknown function (DUF2517) CEQ20_11565 ENOG4105C08 Histidine kinase CEQ20_11570 ENOG4105EEX Two component transcriptional regulator (Winged helix family CEQ20_11585 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 CEQ20_11615 ENOG4105EZV Transcriptional regulator CEQ20_11620 ENOG4105VCP PTS System CEQ20_11625 ENOG4105CK1 PTS System CEQ20_11630 ENOG4105VZJ PTS System CEQ20_11645 ENOG41086WQ Protein CrcB homolog CEQ20_11650 ENOG4107SVH Potassium channel protein CEQ20_11660 ENOG4105XXV Acid-resistance protein CEQ20_11680 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) CEQ20_11710 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) CEQ20_11715 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) CEQ20_11720 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEQ20_11725 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CEQ20_11730 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein CEQ20_11735 ENOG4105VEQ Cold shock protein CEQ20_11745 ENOG4108SAJ Protein of unknown function (DUF1198) CEQ20_11750 ENOG4108WMJ Protein of unknown function (DUF2002) CEQ20_11775 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) CEQ20_11780 ENOG4108IJ7 Glycine betaine CEQ20_11785 ENOG4108HQS Glycine betaine CEQ20_11790 ENOG4105GIJ Glycine betaine CEQ20_11800 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease CEQ20_11810 ENOG4108JDX DNA polymerase iii, epsilon subunit CEQ20_11820 ENOG4105D1A Methyltransferase CEQ20_11830 ENOG4105E9H Lytic Murein transglycosylase CEQ20_11855 ENOG4105CV8 reductase CEQ20_11890 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase CEQ20_11900 ENOG4108UMI ABC transporter, permease CEQ20_11905 ENOG4105D01 (LipO)protein CEQ20_11910 ENOG4108R8X outer membrane lipoprotein CEQ20_11915 ENOG4108R96 Methyltransferase, YaeB family CEQ20_11925 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion CEQ20_11930 ENOG4108YZN class I peptide chain release factor CEQ20_11935 ENOG4108VWS Yaeq family CEQ20_11945 ENOG4105M1T rho-binding antiterminator CEQ20_11960 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase CEQ20_11970 ENOG4105C0B DNA polymerase III (alpha subunit) CEQ20_11980 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) CEQ20_12000 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) CEQ20_12010 ENOG4105DZP Membrane-associated zinc metalloprotease CEQ20_12015 ENOG4105KNE Phosphatidate cytidylyltransferase CEQ20_12020 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) CEQ20_12055 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) CEQ20_12075 ENOG4105QDK Flavodoxin CEQ20_12080 ENOG4105DR9 pseudouridine synthase CEQ20_12085 ENOG4105WP7 tRNA pseudouridine synthase C CEQ20_12100 ENOG4105EWT decarboxylase family CEQ20_12120 ENOG4105M08 Membrane CEQ20_12125 ENOG4105ETT transcriptional Regulator, LysR family CEQ20_12135 ENOG4105C9B Cysteine desulfurase CEQ20_12140 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) CEQ20_12145 ENOG4105CUZ uba thif-type nad fad binding protein CEQ20_12150 ENOG4105CA3 membrane-bound lytic murein transglycosylase CEQ20_12170 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CEQ20_12180 ENOG4107QYX exodeoxyribonuclease v alpha CEQ20_12185 ENOG4107QKA exodeoxyribonuclease V beta CEQ20_12190 ENOG4107QXK peptidase CEQ20_12195 ENOG4105DSY exodeoxyribonuclease V, gamma CEQ20_12235 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase CEQ20_12260 ENOG4105CPC Aldo Keto reductase CEQ20_12290 ENOG41060NJ transcriptional regulator CEQ20_12295 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) CEQ20_12300 ENOG4105RQF LysR family Transcriptional regulator CEQ20_12305 ENOG4105F27 Major Facilitator CEQ20_12310 ENOG4105EJC lysr family transcriptional regulator CEQ20_12325 ENOG4105C8Q Methyl-accepting chemotaxis CEQ20_12385 ENOG4105D7Q type ii secretion system CEQ20_12395 ENOG4107QHF type ii secretion system protein e CEQ20_12415 ENOG4107B2H carbonic anhydrase CEQ20_12445 ENOG4105CBG Sulfatase CEQ20_12450 ENOG4105E98 transcriptional regulator DeoR family CEQ20_12455 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of CEQ20_12460 ENOG4105E70 isomerase CEQ20_12465 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB CEQ20_12470 ENOG4105ETZ PTS System CEQ20_12475 ENOG4105F3R pts system mannose fructose sorbose family iid CEQ20_12480 ENOG4108YTN IIa component CEQ20_12485 ENOG4105CE4 GlcNAc 6-P deacetylase CEQ20_12490 ENOG4105CHR reductase CEQ20_12500 ENOG4105C4X radical SAM domain protein CEQ20_12505 ENOG4105ENH Sulfatase CEQ20_12515 ENOG4105D2N Aldolase CEQ20_12535 ENOG4105DPW Major facilitator superfamily MFS_1 CEQ20_12545 ENOG4105ETE Transcriptional regulator (LacI family CEQ20_12555 ENOG4105CI1 PTS System CEQ20_12560 ENOG4105C4C beta-galactosidase CEQ20_12570 ENOG4105EG2 ABC transporter, permease CEQ20_12580 ENOG4107FKK extracellular solute-binding protein family 1 CEQ20_12595 ENOG4105CNN ABC, transporter CEQ20_12600 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CEQ20_12610 ENOG4108UY0 (LipO)protein CEQ20_12615 ENOG4105NTW Transcriptional regulator CEQ20_12705 ENOG4105WJ3 XRE family Transcriptional regulator CEQ20_12710 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation CEQ20_12750 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) CEQ20_12755 ENOG4105T95 Thiol disulfide interChange protein CEQ20_12760 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CEQ20_12765 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) CEQ20_12770 ENOG4105CT7 inner membrane cred family protein CEQ20_12775 ENOG4105EB3 Histidine kinase CEQ20_12780 ENOG4105E3W Two component transcriptional regulator (Winged helix family CEQ20_12790 ENOG4105Y75 tpr repeat protein CEQ20_12805 ENOG4108UT2 hemolysin iii CEQ20_12850 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family CEQ20_12855 ENOG4105D0A hydroxylase CEQ20_12860 ENOG4107RAQ aminopeptidase CEQ20_12885 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase CEQ20_12890 ENOG4108JQ1 Dehydrogenase CEQ20_12895 ENOG4105E66 phosphoriboisomerase A CEQ20_12905 ENOG4105MPN Membrane CEQ20_12915 ENOG4105D64 Mechanosensitive ion channel CEQ20_12920 ENOG4105D2N Aldolase CEQ20_12935 ENOG4105CV1 Transketolase (EC 2.2.1.1) CEQ20_12945 ENOG4108K0D peptidase, M48 CEQ20_12960 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) CEQ20_12975 ENOG4105RWS endonuclease I CEQ20_12985 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) CEQ20_12990 ENOG4105D7Z glutathione synthase CEQ20_13005 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) CEQ20_13015 ENOG4105CZX twitching motility protein CEQ20_13020 ENOG4105DFA alanine racemase domain protein CEQ20_13025 ENOG4105II7 pyrroline-5-carboxylate reductase CEQ20_13030 ENOG4108VIA integral membrane protein CEQ20_13040 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) CEQ20_13045 ENOG4105CSA Coproporphyrinogen iii oxidase CEQ20_13055 ENOG4105K33 Periplasmic Protein CEQ20_13060 ENOG4105CSV Glutaminase CEQ20_13065 ENOG41090ED Protein with unknown function (DUF469) CEQ20_13075 ENOG4105CEN a g-specific adenine glycosylase CEQ20_13105 ENOG4105CNN ABC, transporter CEQ20_13110 ENOG4105C2J ABC transporter CEQ20_13115 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CEQ20_13120 ENOG4105CXN decarboxylase CEQ20_13140 ENOG4106RHG Yeca family CEQ20_13180 ENOG4108RS6 transposase CEQ20_13325 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEQ20_13415 ENOG4105DUU IucA IucC family protein CEQ20_13420 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) CEQ20_13430 ENOG4105CT4 transporter CEQ20_13440 ENOG4105ETE Transcriptional regulator (LacI family CEQ20_13445 ENOG4105C8P )-transporter CEQ20_13450 ENOG41062WK cellular response to acidity CEQ20_13495 ENOG4105CS6 Rhs element vgr protein CEQ20_13510 ENOG4107EFN gluconate transport system permease 3 CEQ20_13525 ENOG4105BZ1 (ABC) transporter CEQ20_13555 ENOG4105C0W non-ribosomal peptide synthetase CEQ20_13560 ENOG4105C0W non-ribosomal peptide synthetase CEQ20_13565 ENOG4107ZSV Receptor CEQ20_13570 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) CEQ20_13575 ENOG4105CFC Transporter CEQ20_13635 ENOG4105C1P efflux transporter, rnd family, mfp subunit CEQ20_13645 ENOG4105BZU Histidine kinase CEQ20_13660 ENOG4108XTF Outer Membrane Lipoprotein CEQ20_13685 ENOG4107RD7 Flagellar Motor Protein, MotA CEQ20_13715 ENOG4107BRV flagellar capping protein CEQ20_13725 ENOG4105I03 Flagellin CEQ20_13750 ENOG4105E1Q flagellar hook-associated protein CEQ20_13760 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) CEQ20_13765 ENOG4107W7W Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) CEQ20_13770 ENOG4105CGA flagellar basal-body rod protein FlgG CEQ20_13775 ENOG4108KPB Flagellar basal-body rod protein FlgF CEQ20_13780 ENOG4105BZE flagellar hook protein, FlgE CEQ20_13785 ENOG4105W00 Flagellar hook capping protein CEQ20_13790 ENOG4108ZC9 flagellar basal-body rod protein flgc CEQ20_13795 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) CEQ20_13800 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA CEQ20_13820 ENOG4108JIR Flagellum-specific ATP synthase CEQ20_13835 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) CEQ20_13845 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CEQ20_13855 ENOG4105DD5 Flagellar motor switch protein CEQ20_13860 ENOG4105CN7 Flagellar biosynthetic protein FliP CEQ20_13865 ENOG4105VS8 Flagellar biosynthetic protein fliq CEQ20_13870 ENOG4105D19 Role in flagellar biosynthesis (By similarity) CEQ20_13875 ENOG4105D00 flagellar biosynthetic protein flhB CEQ20_13895 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein CEQ20_13905 ENOG4106P2F Pfam:Pili_assembly_C CEQ20_13910 ENOG4106PG1 outer membrane usher protein CEQ20_13920 ENOG4105E03 chitinase CEQ20_13925 ENOG4108M1A Chitin-binding protein CEQ20_14020 ENOG4108ZZF transport protein (ExbD) CEQ20_14025 ENOG4105CWK Biopolymer transport protein, ExbB CEQ20_14030 ENOG4105C28 cystathionine CEQ20_14035 ENOG4108K81 inner membrane protein YghB CEQ20_14040 ENOG4105CF7 AraC family transcriptional regulator CEQ20_14045 ENOG4108I6A alcohol dehydrogenase CEQ20_14055 ENOG4105CV8 reductase CEQ20_14070 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) CEQ20_14080 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase CEQ20_14085 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CEQ20_14095 ENOG4105NF4 modulator of drug activity CEQ20_14100 ENOG4105CR8 Transcriptional regulator CEQ20_14105 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CEQ20_14110 ENOG4105IPS esterase CEQ20_14115 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) CEQ20_14120 ENOG4108SX3 cytoplasmic protein CEQ20_14125 ENOG41087AY ADP-Ribose pyrophosphatase CEQ20_14130 ENOG4105DFG type I secretion outer membrane protein CEQ20_14145 ENOG4106032 Glutathionylspermidine synthase CEQ20_14150 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b CEQ20_14160 ENOG4105W0Z cytoplasmic protein CEQ20_14170 ENOG4105DVH amino acid CEQ20_14185 ENOG4105I7R Adenylate cyclase CEQ20_14190 ENOG4106MWK domain protein CEQ20_14205 ENOG4107ZVW dihydroneopterin aldolase CEQ20_14220 ENOG4105VCC 30S ribosomal protein S21 CEQ20_14225 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) CEQ20_14230 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ20_14260 ENOG4105J12 Multidrug resistance protein mdtN CEQ20_14265 ENOG4108MI0 Resistance protein CEQ20_14275 ENOG4107QK4 glycoside hydrolase, family 3 domain protein CEQ20_14285 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component CEQ20_14295 ENOG4108IJG ABC transporter substrate-binding protein CEQ20_14300 ENOG4107KJX Transcriptional regulator CEQ20_14305 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 CEQ20_14365 ENOG4105CKT filamentous hemagglutinin CEQ20_14370 ENOG4105CKT filamentous hemagglutinin CEQ20_14375 ENOG4105D5K Hemolysin activator protein CEQ20_14410 ENOG4108YK4 Acid-resistance membrane protein CEQ20_14415 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase CEQ20_14430 ENOG4108VKG metal-dependent hydrolase CEQ20_14435 ENOG4105EE0 oxidoreductase CEQ20_14445 ENOG4105P66 Membrane CEQ20_14450 ENOG4105CTX dehydratase CEQ20_14455 ENOG4107QZW Altronate oxidoreductase CEQ20_14465 ENOG4105DPW Major facilitator superfamily MFS_1 CEQ20_14480 ENOG4106W5V Membrane CEQ20_14500 ENOG4105NE1 Conserved Protein CEQ20_14505 ENOG41090KG Inner membrane protein YqjE CEQ20_14515 ENOG4108VBZ doxx family CEQ20_14525 ENOG4105CWB LysR family transcriptional Regulator CEQ20_14530 ENOG4108CNN domain protein CEQ20_14540 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) CEQ20_14560 ENOG4105W4M Transport-associated protein CEQ20_14570 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain CEQ20_14580 ENOG4105BZU Histidine kinase CEQ20_14590 ENOG4105N5T Radical SAM Protein CEQ20_14595 ENOG4105CBC glutamate synthase CEQ20_14600 ENOG4105BZ8 glutamate synthase CEQ20_14610 ENOG4105KB2 stringent starvation protein b CEQ20_14615 ENOG4107MKT Stringent starvation protein a CEQ20_14635 ENOG4105D6Z AFG1 family ATPase CEQ20_14640 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III CEQ20_14645 ENOG4105C0H protease CEQ20_14650 ENOG4105C0H protease CEQ20_14660 ENOG4105VFK BolA family CEQ20_14665 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane CEQ20_14670 ENOG4105E3I toluene tolerance CEQ20_14675 ENOG4107PE3 Mammalian cell entry related domain protein CEQ20_14680 ENOG4105CY3 ABC transporter, permease CEQ20_14685 ENOG4105DHJ ABC, transporter CEQ20_14690 ENOG4105FEU K -dependent Na -Ca exchanger CEQ20_14695 ENOG4105C2X Arabinose 5-phosphate isomerase CEQ20_14700 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase CEQ20_14705 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) CEQ20_14710 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA CEQ20_14715 ENOG4108IUZ ABC transporter CEQ20_14720 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ20_14725 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA CEQ20_14730 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN CEQ20_14745 ENOG41080Z8 PHOSPHOCARRIER protein CEQ20_14765 ENOG4105KME endoribonuclease L-psp CEQ20_14775 ENOG4105D4X repressor CEQ20_14780 ENOG4105C5Y PTS System CEQ20_14785 ENOG4105CG3 alpha amylase, catalytic region CEQ20_14790 ENOG4105NXH GreA GreB family elongation factor CEQ20_14795 ENOG4108XVM Cytochrome b(562) CEQ20_14810 ENOG4105CMS peptidase U62, modulator of DNA gyrase CEQ20_14820 ENOG4105UNR (Barnase) inhibitor CEQ20_14850 ENOG4105CR8 Transcriptional regulator CEQ20_14900 ENOG4105D1U peptidase U62 modulator of DNA gyrase CEQ20_14910 ENOG4105QD6 exported protein CEQ20_14915 ENOG4105C03 ribonuclease CEQ20_14925 ENOG4105VQ7 Rod shape-determining protein MreD CEQ20_14930 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) CEQ20_14935 ENOG4105DFF Rod shape-determining protein mreb CEQ20_14940 ENOG41062P1 Diguanylate cyclase phosphodiesterase CEQ20_14945 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family CEQ20_14965 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein CEQ20_14970 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase CEQ20_14975 ENOG4105RG0 Membrane CEQ20_14980 ENOG4108IA2 Sodium pantothenate symporter CEQ20_14990 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CEQ20_14995 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) CEQ20_15080 ENOG4105QYV Membrane CEQ20_15095 ENOG4105EAH synthase CEQ20_15105 ENOG4105HVQ Regulatory factor of maltose metabolism CEQ20_15130 ENOG4105DFU Cell wall formation (By similarity) CEQ20_15140 ENOG4105F0N pyrophosphate phospho-hydrolase CEQ20_15145 ENOG4108ZHD aig2 family CEQ20_15150 ENOG4105MA0 exported protein CEQ20_15155 ENOG4105CFU surface antigen CEQ20_15165 ENOG4105C37 (CBS) domain CEQ20_15175 ENOG4108UUE Transcriptional regulator CEQ20_15180 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase CEQ20_15185 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic CEQ20_15195 ENOG4108V1T peptidylprolyl cis-trans isomerase CEQ20_15200 ENOG4105FHY Opacity-associated protein A CEQ20_15215 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) CEQ20_15225 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) CEQ20_15235 ENOG4108MXZ Esterase CEQ20_15240 ENOG4105WSB biofilm stress and motility protein A CEQ20_15245 ENOG4105CSU acyl-Coa dehydrogenase CEQ20_15250 ENOG4105C2N RNA methyltransferase TrmH family group 3 CEQ20_15255 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) CEQ20_15275 ENOG4105EPW hflc protein CEQ20_15280 ENOG4107QJR hflk protein CEQ20_15285 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) CEQ20_15305 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase CEQ20_15310 ENOG4105K8N protein family UPF0079, ATPase CEQ20_15315 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) CEQ20_15320 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) CEQ20_15365 ENOG4105EGS Mechanosensitive ion channel CEQ20_15395 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) CEQ20_15400 ENOG4105KPY Small multidrug resistance protein CEQ20_15410 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein CEQ20_15415 ENOG4108ZVF (LipO)protein CEQ20_15445 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter CEQ20_15460 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CEQ20_15465 ENOG4108RC0 Electron transport protein CEQ20_15470 ENOG4105BZ8 glutamate synthase CEQ20_15480 ENOG4108SIC Transcriptional regulator CEQ20_15535 ENOG4105CNA YD repeat protein CEQ20_15625 ENOG41085W3 Transposase CEQ20_15635 ENOG4107QRT dEAD DEAH box helicase CEQ20_15780 ENOG4107QHF type ii secretion system protein e CEQ20_15855 ENOG4105CDU Replicative dna helicase CEQ20_15865 ENOG4105DFP Integrase CEQ20_15980 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEQ20_15990 ENOG4105CDV Ompa motb domain protein CEQ20_16030 ENOG4108Q2J Inner membrane protein YebE CEQ20_16160 ENOG4108MXD gtp-binding protein CEQ20_16165 ENOG4106H6R UPF0380 protein CEQ20_16175 ENOG4105MFG Antirestriction protein CEQ20_16180 ENOG4105W5Q DNA repair protein (RadC CEQ20_16190 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures CEQ20_16195 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles CEQ20_16275 ENOG4105C0A alcohol dehydrogenase CEQ20_16285 ENOG4108UUM single-stranded DNA-binding protein CEQ20_16295 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) CEQ20_16300 ENOG4105MSB protein, conserved in bacteria CEQ20_16305 ENOG4105CGF Aromatic amino acid aminotransferase CEQ20_16310 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) CEQ20_16315 ENOG4105CDU Replicative dna helicase CEQ20_16320 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein CEQ20_16330 ENOG4105P4Z Phage shock protein G CEQ20_16335 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) CEQ20_16340 ENOG4105MYN Zinc uptake regulation protein CEQ20_16350 ENOG41080IJ Diacylglycerol kinase CEQ20_16405 ENOG4108S1B Periplasmic chaperone protein CEQ20_16465 ENOG4105DAX Pfam:DUF2983 CEQ20_16485 ENOG4105D4P Coproporphyrinogen iii oxidase CEQ20_16490 ENOG41090JE Utilization Protein CEQ20_16500 ENOG4107F3C Hemin uptake protein CEQ20_16505 ENOG4107ENK receptor CEQ20_16510 ENOG4106QJH hemin transport protein CEQ20_16515 ENOG4107R4I Periplasmic binding protein CEQ20_16520 ENOG4105EHG Permease protein CEQ20_16530 ENOG4105C28 cystathionine CEQ20_16535 ENOG4105C44 Serine transporter CEQ20_16540 ENOG4105EQ2 LysR family Transcriptional regulator CEQ20_16545 ENOG4105KSU Redox protein CEQ20_16550 ENOG41066VF YeeE YedE family protein CEQ20_16555 ENOG4108IUF type iii secretion CEQ20_16560 ENOG4108TN6 type iii secretion CEQ20_16565 ENOG41083GP type iii secretion CEQ20_16570 ENOG4108HHI Type III secretion system protein CEQ20_16575 ENOG41063Q7 Type III secretion system protein CEQ20_16590 ENOG4108JIR Flagellum-specific ATP synthase CEQ20_16650 ENOG4105BZU Histidine kinase CEQ20_16655 ENOG4105WH1 Two component transcriptional regulator luxr family CEQ20_16660 ENOG4105CK2 sodium dicarboxylate symporter CEQ20_16670 ENOG41062QD Membrane CEQ20_16725 ENOG4108RR8 protoporphyrinogen oxidase CEQ20_16730 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) CEQ20_16735 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein CEQ20_16755 ENOG4107QK7 reductase CEQ20_16765 ENOG4105MDZ Transcriptional activator rfaH CEQ20_16770 ENOG4105D52 delta-aminolevulinic acid dehydratase CEQ20_16780 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) CEQ20_16790 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) CEQ20_16800 ENOG4105JC1 sterol-binding domain protein CEQ20_16810 ENOG4105CGY Dna recombination protein CEQ20_16815 ENOG4108KF1 Membrane CEQ20_16830 ENOG4108I5U Uridine phosphorylase CEQ20_16835 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) CEQ20_16845 ENOG4105DZ2 Transcriptional regulator CEQ20_16850 ENOG4105EMK carboxylate amino acid amine transporter CEQ20_16855 ENOG4105RK9 auxin efflux carrier CEQ20_16860 ENOG4107T6V glycerophosphoryl diester phosphodiesterase CEQ20_16920 ENOG4108IV0 ABC, transporter CEQ20_16925 ENOG4105C0Z ABC transporter CEQ20_16930 ENOG4105CF8 branched-chain amino acid ABC transporter, permease CEQ20_16935 ENOG4105C32 Amino acid ABC transporter (Permease) CEQ20_16940 ENOG4105CP9 extracellular ligand-binding receptor CEQ20_16945 ENOG4105U59 -acetyltransferase CEQ20_16955 ENOG4105CRP Part of the ABC transporter FtsEX involved in CEQ20_16960 ENOG4105CAK Cell division ATP-binding protein ftsE CEQ20_16965 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CEQ20_16965 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) CEQ20_16975 ENOG4106H78 methyltransferase CEQ20_16980 ENOG4105MG3 Membrane CEQ20_16995 ENOG4107FS9 Membrane CEQ20_17010 ENOG4105EX9 Membrane CEQ20_17015 ENOG4108W1V Lipoprotein CEQ20_17020 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) CEQ20_17030 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A CEQ20_17045 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase CEQ20_17055 ENOG4105DQF Hydrolase CEQ20_17060 ENOG4108EUD Lysophospholipase CEQ20_17070 ENOG4105CCF Lysine exporter protein (Lyse ygga) CEQ20_17075 ENOG4105C9U ATP-dependent DNA helicase RecQ CEQ20_17085 ENOG4108VUY thioesterase Superfamily protein CEQ20_17090 ENOG4105FR1 rard protein CEQ20_17095 ENOG4107QUT magnesium and cobalt transport protein CorA CEQ20_17105 ENOG4105EQN UPF0261 protein CEQ20_17115 ENOG4105C4R Atp-dependent dna helicase CEQ20_17120 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant CEQ20_17125 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) CEQ20_17130 ENOG4105CT0 Protein of unknown function, DUF484 CEQ20_17140 ENOG4105S7Z (LipO)protein CEQ20_17155 ENOG4107T0K Adenylate cyclase CEQ20_17170 ENOG41076E6 Uroporphyrinogen-III Synthase CEQ20_17175 ENOG4105ECF c-methyltransferase CEQ20_17180 ENOG410601J HemY protein CEQ20_17205 ENOG4105C85 amino acid CEQ20_17225 ENOG4105EGZ biosynthesis protein CEQ20_17230 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase CEQ20_17235 ENOG4108WJ1 acetyltransferase CEQ20_17240 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) CEQ20_17245 ENOG4105C1B dTDP-glucose 4-6-dehydratase CEQ20_17250 ENOG4108IJ1 Dehydrogenase CEQ20_17255 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase CEQ20_17260 ENOG4105SFE lipopolysaccharide biosynthesis protein CEQ20_17265 ENOG4105ESV Glycosyl transferase, family 4 CEQ20_17275 ENOG4105K63 Thioredoxin CEQ20_17300 ENOG4105C4R Atp-dependent dna helicase CEQ20_17310 ENOG4105KQ5 peptidylprolyl cis-trans isomerase CEQ20_17330 ENOG4105GQR Chaperone CEQ20_17335 ENOG4105CW0 outer membrane usher protein CEQ20_17345 ENOG4108VEV chaperone CEQ20_17385 ENOG4105EMY transcriptional regulator CEQ20_17405 ENOG4105C7B Threonine dehydratase CEQ20_17415 ENOG4105CM2 brancheD-chain amino acid aminotransferase CEQ20_17420 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit CEQ20_17440 ENOG4105C0P Mg chelatase subunit ChlI CEQ20_17445 ENOG4108WFC UPF0438 protein yifE CEQ20_17455 ENOG41062B0 ABC transporter, permease CEQ20_17460 ENOG4107R9N ABC transporter CEQ20_17465 ENOG4105C2J ABC transporter CEQ20_17470 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator CEQ20_17530 ENOG4108Y73 Membrane CEQ20_17545 ENOG4105C5Q Transcriptional regulator CEQ20_17550 ENOG4105EHV domain protein CEQ20_17555 ENOG4107QN2 dihydrolipoyl dehydrogenase CEQ20_17560 ENOG4105YHG TonB family CEQ20_17580 ENOG4105X58 receptor CEQ20_17625 ENOG4105SYT Methylenetetrahydrofolate reductase CEQ20_17630 ENOG4105CFH Aspartokinase CEQ20_17635 ENOG4105C28 cystathionine CEQ20_17640 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) CEQ20_17645 ENOG4108Z12 YiaAB two helix domain-containing protein CEQ20_17655 ENOG4105C25 Primosomal protein n' CEQ20_17665 ENOG4105ETE Transcriptional regulator (LacI family CEQ20_17670 ENOG41063M6 Cell Division Protein CEQ20_17685 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase CEQ20_17710 ENOG4108MBX Secretion Protein CEQ20_17715 ENOG4108JJA ABC, transporter CEQ20_17740 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) CEQ20_17745 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) CEQ20_17750 ENOG4105CBT Fructose-1,6-bisphosphatase CEQ20_17755 ENOG4105DP0 ferredoxin-NADP reductase CEQ20_17760 ENOG4108VTS Membrane CEQ20_17765 ENOG4105EBK exported protein CEQ20_17775 ENOG4107F9Y LysR family transcriptional regulator CEQ20_17785 ENOG4105JSC dimethylmenaquinone methyltransferase CEQ20_17790 ENOG4107QPK )-transporter CEQ20_17800 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein CEQ20_17830 ENOG4105FMW periplasmic CEQ20_17835 ENOG4105E3W Two component transcriptional regulator (Winged helix family CEQ20_17840 ENOG4105E0F Histidine kinase CEQ20_17845 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) CEQ20_17850 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) CEQ20_17855 ENOG4105D7W serine acetyltransferase CEQ20_17875 ENOG4105VW4 glutaredoxin 3 CEQ20_17880 ENOG4107YZP Rhodanese domain protein CEQ20_17890 ENOG41063SB peptidase CEQ20_17895 ENOG4105PXI polysaccharide deacetylase CEQ20_17905 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) CEQ20_17915 ENOG4105XA0 heptosyltransferase ii CEQ20_17920 ENOG4105D16 lipopolysaccharide heptosyltransferase i CEQ20_17925 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase CEQ20_17945 ENOG4105W0E 50S ribosomal protein L33 CEQ20_17965 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase CEQ20_17990 ENOG4105DSJ YicC domain protein CEQ20_18020 ENOG4108YGG dna repair protein CEQ20_18035 ENOG410679B prophage CP4-57 regulatory protein alpA CEQ20_18055 ENOG4105EN6 Membrane CEQ20_18060 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) CEQ20_18070 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) CEQ20_18075 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CEQ20_18080 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase CEQ20_18085 ENOG4105CB5 ATP-dependent DNA helicase recG CEQ20_18095 ENOG4105D6U Sodium Glutamate Symporter CEQ20_18100 ENOG4105C2W permease CEQ20_18105 ENOG4105JV1 AsmA family CEQ20_18110 ENOG4105SUU thioesterase domain CEQ20_18125 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 CEQ20_18135 ENOG4105C5F glutamine synthetase CEQ20_18145 ENOG4105CUX Signal transduction histidine kinase CEQ20_18150 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family CEQ20_18155 ENOG4105D4P Coproporphyrinogen iii oxidase CEQ20_18180 ENOG4105C2M dna polymerase I CEQ20_18185 ENOG4108Z33 Thiol disulfide Interchange Protein CEQ20_18190 ENOG4105E27 serine threonine protein kinase CEQ20_18195 ENOG4105PC1 Conserved Protein CEQ20_18205 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b CEQ20_18245 ENOG4107EJG GntR family transcriptional regulator CEQ20_18250 ENOG4105C0R drug resistance transporter emrb qaca subfamily CEQ20_18260 ENOG4108RVA ribokinase CEQ20_18290 ENOG4108VVK transcriptional Regulator, AsnC CEQ20_18295 ENOG4105QTB Flavodoxin CEQ20_18315 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation CEQ20_18325 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) CEQ20_18370 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) CEQ20_18375 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) CEQ20_18380 ENOG4105C8U phosphate abc transporter CEQ20_18385 ENOG4105E2Z phosphate ABC transporter (Permease CEQ20_18405 ENOG4106PMH Extracellular solute-binding protein family 3 CEQ20_18410 ENOG4105EAD ABC transporter CEQ20_18415 ENOG4105DRP amino acid AbC transporter CEQ20_18420 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 CEQ20_18430 ENOG4105C7N Xanthine uracil vitamin C permease CEQ20_18460 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins CEQ20_18475 ENOG4105VG0 50S ribosomal protein l34 CEQ20_18495 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) CEQ20_18500 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) CEQ20_18505 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) CEQ20_18510 ENOG410667J hydrolase CEQ20_18535 ENOG4105C7B Threonine dehydratase CEQ20_18540 ENOG4105D99 atp gtp-binding protein CEQ20_18545 ENOG4105R2A (LipO)protein CEQ20_18565 ENOG4105JKW Valine--pyruvate aminotransferase CEQ20_18585 ENOG4107T9C Alpha amylase catalytic region CEQ20_18605 ENOG4108ZG0 Ompa motb domain protein CEQ20_18620 ENOG4105HVQ Regulatory factor of maltose metabolism CEQ20_18630 ENOG4108NKR DNA circulation protein CEQ20_18640 ENOG4105PZ7 Baseplate assembly protein CEQ20_18645 ENOG4105WR6 Phage protein, GP46 CEQ20_18650 ENOG4108T86 baseplate J family protein CEQ20_18660 ENOG4106IKR CEQ20_18675 ENOG4108R3E Dna-3-methyladenine glycosylase i CEQ20_18690 ENOG4106JH6 (LipO)protein CEQ20_18695 ENOG4105CTS PTS system mannitol-specific CEQ20_18705 ENOG4105E61 Mannitol repressor protein CEQ20_18710 ENOG4108YYI Protein of unknown function (DUF2810) CEQ20_18725 ENOG4105C8Q Methyl-accepting chemotaxis CEQ20_18730 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) CEQ20_18740 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CEQ20_18745 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) CEQ20_18750 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein CEQ20_18755 ENOG4108MG3 formate dehydrogenase CEQ20_18770 ENOG4105EM7 Selenocysteine-specific translation elongation factor CEQ20_18820 ENOG4105MEV Acyl-transferase CEQ20_18825 ENOG4106EAR Fimbrial protein CEQ20_18835 ENOG4108TTM chaperone CEQ20_18845 ENOG4105CMG Carbohydrate kinase CEQ20_18855 ENOG4105DFW ABC transporter CEQ20_18865 ENOG4107RNG ABC transporter CEQ20_18870 ENOG4105T16 Transcriptional regulator (AraC family) CEQ20_18890 ENOG4106H3A restriction CEQ20_18925 ENOG4108XS9 dna repair protein CEQ20_18935 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures CEQ20_18945 ENOG4105DFP Integrase CEQ20_18965 ENOG4108IPW abc transporter atp-binding protein CEQ20_18970 ENOG4105CM4 permease protein CEQ20_19015 ENOG4105C85 amino acid CEQ20_19025 ENOG4105DIJ Phosphoethanolamine transferase CEQ20_19030 ENOG4108KX4 response regulator CEQ20_19035 ENOG4105BZU Histidine kinase CEQ20_19040 ENOG4105CXY transporter CEQ20_19055 ENOG4105D5K Hemolysin activator protein CEQ20_19065 ENOG4105DEF Extracellular solute-binding protein, family 5 CEQ20_19070 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CEQ20_19075 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEQ20_19080 ENOG4105C3U ABC transporter CEQ20_19085 ENOG4108JQ7 (ABC) transporter CEQ20_19090 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) CEQ20_19095 ENOG4105BZU Histidine kinase CEQ20_19100 ENOG4108PU9 oligogalacturonate-specific porin CEQ20_19120 ENOG4105CS0 peptidase CEQ20_19125 ENOG4107SS6 2-dehydro-3-deoxygluconokinase CEQ20_19130 ENOG4105VSH 4-oxalocrotonate tautomerase CEQ20_19135 ENOG4105CMB EAL domain-containing protein CEQ20_19140 ENOG41066T0 asmA family CEQ20_19145 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) CEQ20_19150 ENOG4107H3J ribonuclease CEQ20_19175 ENOG4105BZW Glycerate kinase CEQ20_19180 ENOG4107QQ0 gntp family CEQ20_19190 ENOG4107VHA regulatoR CEQ20_19195 ENOG4105DC8 reductase CEQ20_19200 ENOG4105D6S protein involved in catabolism of external DNA CEQ20_19205 ENOG4105DGW oligopeptidase A CEQ20_19225 ENOG4108M6U Universal stress protein A CEQ20_19235 ENOG4105CJ3 phosphate transporter CEQ20_19240 ENOG4105CBX hi0933 family CEQ20_19255 ENOG4105CNN ABC, transporter CEQ20_19260 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator CEQ20_19270 ENOG4105D2N Aldolase CEQ20_19280 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CEQ20_19295 ENOG4105C2I pirin domain protein CEQ20_19300 ENOG4105DIQ Transcriptional regulator CEQ20_19305 ENOG4105C6Z Gluconate CEQ20_19315 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family CEQ20_19320 ENOG4105GMB type VI secretion system effector, hcp1 family CEQ20_19335 ENOG41076UM multiple antibiotic resistance (MarC)-related protein CEQ20_19340 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) CEQ20_19365 ENOG4108HRK Histidine kinase CEQ20_19390 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CEQ20_19395 ENOG4105C6V Glycerol-3-phosphate dehydrogenase CEQ20_19410 ENOG4105E98 transcriptional regulator DeoR family CEQ20_19430 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) CEQ20_19435 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) CEQ20_19445 ENOG4105MJ2 Competence protein CEQ20_19455 ENOG4105RID UPF0379 protein yhcN CEQ20_19470 ENOG4105XFK Ferrous iron transport protein A CEQ20_19475 ENOG4105BZM domain protein CEQ20_19480 ENOG4108RRZ Transcription elongation factor GreB CEQ20_19485 ENOG4105DPZ Two component transcriptional regulator (Winged helix family CEQ20_19490 ENOG4105E0F Histidine kinase CEQ20_19510 ENOG4105VEJ Heat shock protein CEQ20_19515 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 CEQ20_19520 ENOG4105DQY intracellular growth attenuator CEQ20_19530 ENOG4107RK2 ADP-ribose diphosphatase NudE CEQ20_19535 ENOG4108JQC penicillin-binding protein 1A CEQ20_19565 ENOG4105E4G Type IV pilus CEQ20_19595 ENOG4105DJV ribulose-phosphate 3-epimerase CEQ20_19600 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) CEQ20_19605 ENOG4105C31 Tryptophanyl-tRNA synthetase CEQ20_19615 ENOG4107V9H nitrite transporter CEQ20_19620 ENOG4105WZK nitrite reductase NADPH small subunit CEQ20_19625 ENOG4107QZF nitrite reductase NADPH large subunit CEQ20_19630 ENOG4105DZC cytosine deaminase CEQ20_19645 ENOG41060NJ transcriptional regulator CEQ20_19650 ENOG4105F8D glycoside hydrolase family 4 CEQ20_19655 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) CEQ20_19660 ENOG4105D7A ATP-binding protein CEQ20_19670 ENOG4105C8Y Acetylornithine aminotransferase CEQ20_19675 ENOG410613R integral membrane protein, YccS YhfK family CEQ20_19685 ENOG4108UKZ OsmC family CEQ20_19695 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) CEQ20_19705 ENOG4105DNZ Alpha Beta Hydrolase CEQ20_19715 ENOG4106FTQ Taurine ABC transporter, periplasmic CEQ20_19725 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component CEQ20_19730 ENOG4105E2B Taurine dioxygenase CEQ20_19745 ENOG4105C5H ABC transporter CEQ20_19750 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein CEQ20_19760 ENOG4105VKU nucleicacid-binding protein CEQ20_19765 ENOG4108YZY peptidylprolyl cis-trans isomerase CEQ20_19780 ENOG4108V1T peptidylprolyl cis-trans isomerase CEQ20_19785 ENOG4105WWK YheO domain protein CEQ20_19810 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) CEQ20_19865 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) CEQ20_19875 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) CEQ20_19880 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) CEQ20_19890 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal CEQ20_19935 ENOG4105VPB 50S ribosomal protein L30 CEQ20_19945 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) CEQ20_19950 ENOG41067V7 50S ribosomal protein L36 CEQ20_19965 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) CEQ20_19980 ENOG4105W1Y Transcriptional regulator CEQ20_19985 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system CEQ20_19995 ENOG4105C1A potassium transporter peripheral membrane CEQ20_20015 ENOG4105C79 DNA protecting protein DprA CEQ20_20025 ENOG4108WI1 Dna topoisomerase CEQ20_20040 ENOG4108Z0R Transferase CEQ20_20080 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase CEQ20_20120 ENOG4105PM1 preprotein translocase subunit SecE CEQ20_20125 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) CEQ20_20165 ENOG4105D41 biosynthesis protein thiH CEQ20_20180 ENOG4105D06 uba thif-type nad fad binding protein CEQ20_20190 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) CEQ20_20215 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) CEQ20_20220 ENOG4105R2J Conserved Protein CEQ20_20230 ENOG4108T8B Protein of unknown function (DUF1481) CEQ20_20235 ENOG4105C12 Phosphoribosylglycinamide synthetase CEQ20_20295 ENOG4107QP3 malate synthase g CEQ20_20300 ENOG4108I9X Isocitrate lyase CEQ20_20310 ENOG41069M3 Transcriptional regulator CEQ20_20315 ENOG4105C3R Methionine synthase CEQ20_20330 ENOG4105CFH Aspartokinase CEQ20_20345 ENOG4105EG2 ABC transporter, permease CEQ20_20350 ENOG4105D56 permease protein CEQ20_20355 ENOG4107FKK extracellular solute-binding protein family 1 CEQ20_20375 ENOG4107W52 maltose operon periplasmic protein CEQ20_20385 ENOG4108WC9 type VI secretion system effector, hcp1 family CEQ20_20435 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEQ20_20470 ENOG4105CS6 Rhs element vgr protein CEQ20_20480 ENOG4105CNA YD repeat protein CEQ20_20510 ENOG4105CS6 Rhs element vgr protein CEQ20_20570 ENOG4105CS6 Rhs element vgr protein CEQ20_20585 ENOG4107TYG Oxidoreductase domain-containing protein CEQ20_20595 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) CEQ20_20600 ENOG4108RVA ribokinase CEQ20_20605 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CEQ20_20625 ENOG4105GVF (ABC) transporter CEQ20_20635 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component CEQ20_20645 ENOG4105DFP Integrase CEQ20_20670 ENOG4105CSH Transporter CEQ20_20675 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase CEQ20_20690 ENOG4108XTF Outer Membrane Lipoprotein CEQ20_20700 ENOG4105VEQ Cold shock protein CEQ20_20705 ENOG4105VEQ Cold shock protein CEQ20_20710 ENOG4105VEQ Cold shock protein CEQ20_20725 ENOG4105CYM Glutathione S-transferase CEQ20_20730 ENOG4105C2X Arabinose 5-phosphate isomerase CEQ20_20735 ENOG4105EF1 ribulokinase CEQ20_20745 ENOG4105CNN ABC, transporter CEQ20_20750 ENOG4105C2J ABC transporter CEQ20_20760 ENOG4105D1S lipid A biosynthesis CEQ20_20770 ENOG4105EEQ Na H antiporter CEQ20_20775 ENOG4105C7N Xanthine uracil vitamin C permease CEQ20_20815 ENOG4105XB7 anti-repressor protein CEQ20_20845 ENOG4105GMB type VI secretion system effector, hcp1 family CEQ20_20885 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase CEQ20_20890 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) CEQ20_20895 ENOG4105HBR Rna-binding protein CEQ20_20905 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) CEQ20_20910 ENOG4105EEI dihydropteroate synthase CEQ20_20940 ENOG4105CHV Transcription elongation factor NusA CEQ20_20980 ENOG4105C1J atp-dependent rna helicase CEQ20_20990 ENOG4105DEN Luciferase family CEQ20_21000 ENOG4105BZS acriflavin resistance protein CEQ20_21005 ENOG4105ENJ RND efflux system, outer membrane lipoprotein CEQ20_21010 ENOG4106RZ4 Peptidase U32 CEQ20_21015 ENOG4105CFP Peptidase U32 CEQ20_21025 ENOG4105XPQ lipid carrier protein CEQ20_21030 ENOG4108YYD acetyltransferase CEQ20_21055 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component CEQ20_21060 ENOG4105DRS transport system, permease CEQ20_21080 ENOG4105K4T epimerase CEQ20_21085 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein CEQ20_21090 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) CEQ20_21095 ENOG4105FD8 phosphonate metabolism protein PhnM CEQ20_21100 ENOG4105HRV phosphonate c-p lyase system protein phnl CEQ20_21105 ENOG4105ENV phosphonate C-P lyase system protein PhnK CEQ20_21110 ENOG4105FT8 Phosphonate metabolism CEQ20_21120 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH CEQ20_21125 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG CEQ20_21130 ENOG4107RJJ Transcriptional regulator CEQ20_21135 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) CEQ20_21140 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase CEQ20_21145 ENOG4108JQ7 (ABC) transporter CEQ20_21150 ENOG4105C3U ABC transporter CEQ20_21155 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component CEQ20_21160 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component CEQ20_21170 ENOG4105XEP YhcH YjgK YiaL family protein CEQ20_21180 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) CEQ20_21185 ENOG4108MJ3 acetyltransferase CEQ20_21195 ENOG4105MYG DNA polymerase iii, chi subunit CEQ20_21205 ENOG4108M8S permease YjgP YjgQ family protein CEQ20_21210 ENOG4108K5H permease YjgP YjgQ family protein CEQ20_21275 ENOG4108KZE transcriptional regulator CEQ20_21280 ENOG4108MXD gtp-binding protein CEQ20_21295 ENOG4105JXR Protein of unknown function (DUF3296) CEQ20_21305 ENOG4106H6R UPF0380 protein CEQ20_21315 ENOG4105MFG Antirestriction protein CEQ20_21320 ENOG4108XS9 dna repair protein CEQ20_21325 ENOG4105ZS6 Protein of unknown function (DUF987) CEQ20_21330 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles CEQ20_21365 ENOG4105DZR Type I site-specific deoxyribonuclease CEQ20_21385 ENOG4108M3P Membrane CEQ20_21395 ENOG4106R3P AraC family transcriptional regulator CEQ20_21400 ENOG4108XCZ PTS System CEQ20_21405 ENOG4108YRF PTS System CEQ20_21410 ENOG4105DM4 PTS System CEQ20_21415 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) CEQ20_21420 ENOG4105RI1 glycoprotein receptor CEQ20_21460 ENOG4105DKT Transcriptional regulator CEQ20_21470 ENOG4105DKP glycosyl transferase, family 9 CEQ20_21520 ENOG410624X efflux transporter, rnd family, mfp subunit CEQ20_21525 ENOG4105BZS acriflavin resistance protein CEQ20_21555 ENOG4105BZU Histidine kinase CEQ20_21560 ENOG4105YBH Protein of unknown function (DUF1435) CEQ20_21585 ENOG4108WPU DNA polymerase III subunit psi CEQ20_21590 ENOG4105KEG ribosomal-protein-alanine acetyltransferase CEQ20_21600 ENOG4105K3G Periplasmic Protein CEQ20_21610 ENOG4108NRW Phospholipase, patatin family CEQ20_21615 ENOG4105EYA deoxyribonuclease CEQ20_21620 ENOG4105D9N nucleoside CEQ20_21630 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) CEQ20_21650 ENOG41062Z9 Membrane CEQ20_21655 ENOG4105EAC phosphoserine phosphatase CEQ20_21660 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) CEQ20_21665 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase CEQ20_21675 ENOG4105C5H ABC transporter CEQ20_21680 ENOG41090EK ompa motb domain protein CEQ20_21685 ENOG4108KHX Diguanylate cyclase CEQ20_21700 ENOG4107SC1 transglycosylase CEQ20_21705 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) CEQ20_21720 ENOG4105UEI Transcriptional Regulator AraC Family CEQ20_21730 ENOG4108RH0 Crea protein CEQ20_21735 ENOG41065U4 response regulator CEQ20_21775 ENOG4108RIR Molybdenum cofactor biosynthesis protein CEQ20_21790 ENOG4106HK8 GPR1 FUN34 yaaH family protein CEQ20_21810 ENOG41063Z6 transcriptional regulator, lysR family CEQ20_21830 ENOG4105DTN riboflavin biosynthesis protein ribF CEQ20_21845 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase CEQ20_21865 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain CEQ20_21870 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain CEQ20_21875 ENOG4108NIW Leucine export protein LeuE CEQ20_21880 ENOG4105DWK Membrane CEQ20_21890 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) CEQ20_21930 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) CEQ20_21945 ENOG4105D3G Pseudouridine synthase CEQ20_21990 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit CEQ20_21995 ENOG4105CS6 Rhs element vgr protein CEQ20_22050 ENOG4105CQ2 DNA polymerase CEQ20_22055 ENOG4108KF1 Membrane CEQ20_22065 ENOG4106SMU thiamine transporter membrane protein CEQ20_22070 ENOG4105DP9 ABC transporter CEQ20_22090 ENOG4105S8Q sugar efflux transporter CEQ20_22105 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) CEQ20_22125 ENOG41064T2 transcriptional regulator, lysR family CEQ20_22135 ENOG4108IQE Amp-dependent synthetase and ligase CEQ20_22145 ENOG4105C7K acetolactate synthase CEQ20_22150 ENOG4108ZP8 Acetolactate synthase small subunit CEQ20_22160 ENOG4107B7Y DNA-binding transcriptional regulator FruR CEQ20_22165 ENOG4108RNS Exports L-alanine (By similarity) CEQ20_22185 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) CEQ20_22190 ENOG4105CJN penicillin-binding protein CEQ20_22195 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) CEQ20_22200 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) CEQ20_22215 ENOG4105CNI cell division protein FtsW CEQ20_22235 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) CEQ20_22240 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) CEQ20_22245 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) CEQ20_22275 ENOG4105M6F mutator MutT protein CEQ20_22290 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) CEQ20_22305 ENOG4105D7Q type ii secretion system CEQ20_22310 ENOG4107QHF type ii secretion system protein e CEQ20_22315 ENOG4108ZUW Major pilin subunit CEQ20_22320 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase CEQ20_22325 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase CEQ20_22330 ENOG4106A72 regulatory protein AmpE CEQ20_22335 ENOG4105C85 amino acid CEQ20_22345 ENOG41073TP transcriptional regulator CEQ20_22350 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) CEQ20_22355 ENOG4107QSN dihydrolipoamide acetyltransferase CEQ20_22360 ENOG4107QN2 dihydrolipoyl dehydrogenase CEQ20_22365 ENOG4107QIJ Aconitate hydratase 2 CEQ20_22375 ENOG4105RPH Inner membrane protein YddG CEQ20_22390 ENOG4108ZRK uncharacterized protein yacC CEQ20_22395 ENOG4105E3B Multicopper oxidase CEQ20_22400 ENOG4108UGV hypoxanthine phosphoribosyltransferase CEQ20_22405 ENOG41077A9 carbonic anhydrase CEQ20_22410 ENOG4105DA5 (ABC) transporter CEQ20_22415 ENOG4105E3A (ABC) transporter CEQ20_22420 ENOG4107BJW polysaccharide deacetylase CEQ20_22440 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CEQ20_22445 ENOG4105DJ0 Poly(A) Polymerase CEQ20_22450 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) CEQ20_22460 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters CEQ20_22475 ENOG4107XID 2'-5' rna ligase CEQ20_22480 ENOG4105CQ7 ATP-dependent helicase CEQ20_22485 ENOG4105BZ4 penicillin-binding protein CEQ20_22490 ENOG4105E0A ABC, transporter CEQ20_22495 ENOG4105J76 Periplasmic binding protein CEQ20_22500 ENOG4105S6R Iron-hydroxamate transporter permease subunit CEQ20_22520 ENOG4105EN6 Membrane CEQ20_22540 ENOG4105C0H protease CEQ20_22545 ENOG4105BZU Histidine kinase CEQ20_22555 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) CEQ20_22560 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) CEQ20_22565 ENOG4105DXN mazG family CEQ20_22585 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) CEQ20_22590 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase CEQ20_22650 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) CEQ20_22655 ENOG4105N0Z inner membrane protein ygbE CEQ20_22690 ENOG4108K5P (LipO)protein CEQ20_22695 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) CEQ20_22705 ENOG4108YZG isomerase CEQ20_22710 ENOG4105CPQ Dehydrogenase CEQ20_22715 ENOG4105CHR reductase CEQ20_22720 ENOG4105CMT Dihydroxyacetone kinase CEQ20_22730 ENOG4105DKT Transcriptional regulator CEQ20_22755 ENOG4105E89 ABC transporter CEQ20_22760 ENOG4105CA0 peroxidase CEQ20_22770 ENOG4105D05 Receptor CEQ20_22780 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity)