locus-tag class description EGX53_00040 ENOG4105D5G Transposase EGX53_00095 ENOG4105EZN Cobyrinic acid ac-diamide synthase EGX53_00100 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB EGX53_00175 ENOG4108C33 Resolvase EGX53_00180 ENOG4105D13 transposase EGX53_00235 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) EGX53_00245 ENOG4106CQM replication EGX53_00490 ENOG4108R99 pseudouridine synthase EGX53_00495 ENOG4108HMX isocitrate dehydrogenase (NADP) EGX53_00500 ENOG4106NDP Transcriptional regulator EGX53_00510 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor EGX53_00515 ENOG4105ECR NmrA family EGX53_00520 ENOG4105KVH Transcriptional regulator EGX53_00525 ENOG4105D6F Phosphatase EGX53_00530 ENOG41061EV selenium-binding protein YdfZ EGX53_00540 ENOG4108XM1 transcriptional regulator AsnC family EGX53_00545 ENOG4105GSJ Inner membrane protein ylaC EGX53_00560 ENOG4105VEQ Cold shock protein EGX53_00570 ENOG4105C8Q Methyl-accepting chemotaxis EGX53_00575 ENOG4105KT7 mgtC SapB transporter EGX53_00580 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic EGX53_00590 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region EGX53_00595 ENOG4107RD7 Flagellar Motor Protein, MotA EGX53_00600 ENOG4105ER2 Ompa motb domain protein EGX53_00605 ENOG4105CBS Chea signal transduction histidine kinase EGX53_00610 ENOG4108V3W Chemotaxis protein, CheW EGX53_00625 ENOG4105C8Q Methyl-accepting chemotaxis EGX53_00635 ENOG4105BZU Histidine kinase EGX53_00645 ENOG4108VYJ response regulator receiver protein EGX53_00650 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) EGX53_00660 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EGX53_00675 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EGX53_00705 ENOG4105WT8 Protein of unknown function (DUF1480) EGX53_00720 ENOG4105GQR Chaperone EGX53_00740 ENOG4105DY2 Paraquat-inducible protein b EGX53_00745 ENOG4105H2K paraquat-inducible protein a EGX53_00750 ENOG4108ZGC gaf domain protein EGX53_00760 ENOG4105CN1 protease EGX53_00775 ENOG4105H8W Fimbrial protein EGX53_00780 ENOG4108VEV chaperone EGX53_00795 ENOG4108VEV chaperone EGX53_00800 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX53_00805 ENOG4105CAZ oligogalacturonide lyase EGX53_00815 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EGX53_00820 ENOG4108ETY sodium dicarboxylate symporter EGX53_00825 ENOG4107K5X Membrane-bound metal-dependent hydrolase EGX53_00830 ENOG4108PU9 oligogalacturonate-specific porin EGX53_00835 ENOG4105WEM extracellular solute-binding protein EGX53_00845 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component EGX53_00850 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component EGX53_00855 ENOG41061NF Pectate lyase EGX53_00860 ENOG4105CHR reductase EGX53_00870 ENOG4105M5J Cupin 2, conserved barrel domain protein EGX53_00890 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 EGX53_00895 ENOG4107PN8 YfeABCD locus regulator EGX53_00900 ENOG4105FGM Fructosamine kinase EGX53_00910 ENOG4105CC5 ABC transporter EGX53_00915 ENOG4105CC5 ABC transporter EGX53_00920 ENOG4105DIK (ABC) transporter EGX53_00925 ENOG4105DSE periplasmic solute binding protein EGX53_00950 ENOG41087WU EGX53_00990 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) EGX53_01005 ENOG4108V06 Glutathione peroxidase EGX53_01010 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) EGX53_01055 ENOG4108QBX (LipO)protein EGX53_01070 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EGX53_01080 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) EGX53_01090 ENOG4105IPI Membrane EGX53_01095 ENOG4105CQB FAD linked oxidase domain protein EGX53_01100 ENOG4105KA0 thioesterase Superfamily protein EGX53_01110 ENOG4108Z4V iron-sulfur cluster assembly EGX53_01115 ENOG4105DIW FeS assembly protein SUFB EGX53_01120 ENOG4105C3K feS assembly ATPase SufC EGX53_01125 ENOG4105JRK feS assembly protein SufD EGX53_01140 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein EGX53_01145 ENOG4105KMX major outer membrane lipoprotein EGX53_01150 ENOG4105CA9 Pyruvate kinase EGX53_01180 ENOG4108R6K riboflavin synthase, subunit alpha EGX53_01185 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase EGX53_01190 ENOG4105CZQ inner membrane transport protein YdhC EGX53_01195 ENOG4105F52 Transcriptional regulator EGX53_01210 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EGX53_01215 ENOG4105K4H Nlp p60 protein EGX53_01225 ENOG4105M2J Glutaredoxin EGX53_01240 ENOG4108UYE Lactoylglutathione lyase EGX53_01250 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EGX53_01255 ENOG4108WUH Transcriptional regulator, TetR family EGX53_01265 ENOG4108XTF Outer Membrane Lipoprotein EGX53_01275 ENOG410642K Lysozyme inhibitor EGX53_01295 ENOG4108K3A Glutathione S-transferase EGX53_01300 ENOG4108ZR5 Conserved Protein EGX53_01305 ENOG41069YE inner membrane protein yohC EGX53_01310 ENOG4105DUX Transporter EGX53_01315 ENOG4105Q4T oxidoreductase EGX53_01320 ENOG4108JQ2 peptide transport system atp-binding protein EGX53_01325 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein EGX53_01330 ENOG4108EU3 peptide transport system, permease EGX53_01335 ENOG4108I5W peptide transport system, permease protein EGX53_01340 ENOG4108HIY periplasmic EGX53_01350 ENOG4105E51 psp operon transcriptional activator EGX53_01355 ENOG41087YS Phage shock protein A EGX53_01360 ENOG4105YYT phage shock protein B EGX53_01365 ENOG4105FM1 phage shock protein C EGX53_01375 ENOG4105CM6 amino acid regulated cytosolic protein EGX53_01400 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) EGX53_01405 ENOG4107S8C mandelate racemase muconate lactonizing EGX53_01410 ENOG4105KXI murein peptide amidase A EGX53_01415 ENOG4107QSI ABC, transporter EGX53_01445 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) EGX53_01455 ENOG4105KT7 mgtC SapB transporter EGX53_01465 ENOG41090X5 Heat shock protein hslJ EGX53_01470 ENOG4105C5I Dehydrogenase EGX53_01475 ENOG4107H52 Dicarboxylate transport EGX53_01480 ENOG410689M (LipO)protein EGX53_01485 ENOG4105WXT Conserved Protein EGX53_01490 ENOG4105DEI Mannitol dehydrogenase EGX53_01495 ENOG4105DKT Transcriptional regulator EGX53_01505 ENOG4105CQ7 ATP-dependent helicase EGX53_01520 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap EGX53_01535 ENOG4105DS1 cytochrome b561 EGX53_01560 ENOG4105CTD carboxy-peptidase EGX53_01565 ENOG4105JJR Histidine kinase EGX53_01570 ENOG4107EXC regulatoR EGX53_01580 ENOG4105D5Q Arginine ornithine antiporter EGX53_01585 ENOG4105C5D exported protein EGX53_01595 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EGX53_01600 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) EGX53_01605 ENOG4105Q9Y Universal stress protein EGX53_01610 ENOG4105DS0 Transcriptional regulator, Crp Fnr family EGX53_01615 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EGX53_01630 ENOG4105PAD Hydrolase EGX53_01635 ENOG4105M71 acetolactate synthase 1 regulatory subunit EGX53_01640 ENOG4105C7K acetolactate synthase EGX53_01670 ENOG4105FYV Amp nucleosidase EGX53_01680 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EGX53_01685 ENOG4107UWC ABC, transporter EGX53_01695 ENOG4105C2J ABC transporter EGX53_01700 ENOG4105CNN ABC, transporter EGX53_01705 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator EGX53_01715 ENOG41060NJ transcriptional regulator EGX53_01720 ENOG4105DFD Na H antiporter EGX53_01725 ENOG4105C87 Aminotransferase class I and II EGX53_01745 ENOG4105DWP Membrane EGX53_01755 ENOG4105C26 Dehydrogenase EGX53_01760 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family EGX53_01765 ENOG4105EMU Dehydrogenase EGX53_01775 ENOG4105KBG Protein of unknown function (DUF1161) EGX53_01785 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) EGX53_01790 ENOG4105DAG ROK family EGX53_01795 ENOG4106NZI LysR family Transcriptional regulator EGX53_01800 ENOG4105D94 Major Facilitator Superfamily EGX53_01810 ENOG4105C9Q fumarate hydratase class II EGX53_01815 ENOG4105EIP mannose-6-phosphate isomerase EGX53_01820 ENOG4106J39 exported protein EGX53_01825 ENOG4105FDP GntR family transcriptional regulator EGX53_01845 ENOG4105DHU Bile acid EGX53_01850 ENOG4105D9R oxidoreductase EGX53_01860 ENOG4105CNN ABC, transporter EGX53_01870 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator EGX53_01885 ENOG4108JJA ABC, transporter EGX53_01895 ENOG4108JJA ABC, transporter EGX53_01900 ENOG4105M9B inner membrane protein ydgK EGX53_01920 ENOG4105UEI Transcriptional Regulator AraC Family EGX53_01930 ENOG4108UQQ Electron transport complex EGX53_01940 ENOG4105CSM endonuclease III EGX53_01945 ENOG4105EXW epimerase dehydratase EGX53_01950 ENOG4105CSP Major Facilitator Superfamily EGX53_01960 ENOG4105D22 carbon starvation protein EGX53_01965 ENOG4105VCD cytoplasmic protein EGX53_01970 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) EGX53_01980 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase EGX53_01985 ENOG41061RM osmotically inducible lipoprotein EGX53_01990 ENOG4108ZJT translation initiation factor, Sui1 EGX53_02005 ENOG4105CFV Tetratricopeptide repeat protein EGX53_02010 ENOG4105Q4A inner membrane protein yciS EGX53_02015 ENOG4105EYK Phosphatidylglycerophosphatase B EGX53_02020 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) EGX53_02025 ENOG4107QM5 aconitate hydratase EGX53_02035 ENOG4107R11 Transcriptional regulator EGX53_02040 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EGX53_02050 ENOG4105RKX Protein of unknown function (DUF2498) EGX53_02055 ENOG4105ERU peptidase EGX53_02060 ENOG4105UBK short-chain dehydrogenase reductase EGX53_02065 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase EGX53_02070 ENOG4105FE9 pseudouridine synthase EGX53_02075 ENOG4107RTD sua5 ycio yrdc ywlc family protein EGX53_02080 ENOG4105DB7 PHP domain protein EGX53_02100 ENOG4105DDQ anthranilate synthase EGX53_02110 ENOG4105DK0 Indole-3-glycerol phosphate synthase EGX53_02130 ENOG4105EIF outer membrane protein W EGX53_02160 ENOG4105NAU thioesterase Superfamily protein EGX53_02165 ENOG410822N TonB family EGX53_02170 ENOG4105K9H YciI-like protein EGX53_02185 ENOG4108T1M outer membrane protein x EGX53_02210 ENOG4108JQ7 (ABC) transporter EGX53_02215 ENOG4105C3U ABC transporter EGX53_02220 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EGX53_02230 ENOG4107QSI ABC, transporter EGX53_02235 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein EGX53_02245 ENOG4108EKI Dehydrogenase EGX53_02250 ENOG4107104 thymidine kinase EGX53_02260 ENOG4108RS6 transposase EGX53_02265 ENOG4105C6Y Udp-glucose 6-dehydrogenase EGX53_02270 ENOG4105I93 response regulator EGX53_02280 ENOG4105CIY formyltetrahydrofolate deformylase EGX53_02305 ENOG4105SKE transcriptional Regulator LysR family EGX53_02310 ENOG4105CGK Exodeoxyribonuclease III EGX53_02315 ENOG4105M6F mutator MutT protein EGX53_02320 ENOG4105MTM Protein of unknown function (DUF1496) EGX53_02325 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) EGX53_02335 ENOG41069NU Nitroreductase EGX53_02340 ENOG4105D07 Signal peptide peptidase, SppA EGX53_02345 ENOG4105HDK L-asparaginase EGX53_02350 ENOG4108RWI nicotinamidase EGX53_02355 ENOG4105VUT cytoplasmic protein EGX53_02370 ENOG4105DSB aldose 1-epimerase EGX53_02375 ENOG4105GNX MltA-interacting MipA family protein EGX53_02385 ENOG4105CYN Serine protein kinase EGX53_02400 ENOG4105HEI LysR family (Transcriptional regulator EGX53_02405 ENOG4105EUB pirin domain protein EGX53_02410 ENOG4105CNH Multidrug resistance protein MdtL EGX53_02420 ENOG4105ED1 spovr family EGX53_02455 ENOG4105C3J Cysteine desulfurase EGX53_02470 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase EGX53_02475 ENOG4105CVE Lytic murein transglycosylase EGX53_02495 ENOG4107QMS site-determining protein EGX53_02500 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) EGX53_02505 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) EGX53_02510 ENOG4105CEY Amp-dependent synthetase and ligase EGX53_02520 ENOG4105Y4Z Outer Membrane Lipoprotein EGX53_02525 ENOG41072GX Peptidase M22 Glycoprotease EGX53_02530 ENOG4105DVT helicase EGX53_02535 ENOG4105M4H endoribonuclease L-psp EGX53_02550 ENOG4108UHU Aldolase EGX53_02560 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase EGX53_02565 ENOG4106KNT transcriptional regulator EGX53_02570 ENOG4105CA9 Pyruvate kinase EGX53_02580 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase EGX53_02585 ENOG4105DR5 peptidase EGX53_02590 ENOG4105NXV High-affinity zinc uptake system protein EGX53_02600 ENOG4105FAV ABC, transporter EGX53_02630 ENOG4108TIT dATP pyrophosphohydrolase EGX53_02640 ENOG41081XQ Conserved Protein EGX53_02645 ENOG4105WJG Glutathione EGX53_02665 ENOG4106ZCM YecM protein EGX53_02685 ENOG4105CJR Integral membrane protein (MviN EGX53_02690 ENOG4105EP9 oxidoreductase EGX53_02700 ENOG4105D9U N-acetyltransferase EGX53_02710 ENOG4105F3T (LipO)protein EGX53_02715 ENOG4107XHZ cytoplasmic chaperone TorD family protein EGX53_02730 ENOG4105E2R ROK family EGX53_02735 ENOG4108QXE glycerophosphoryl diester phosphodiesterase EGX53_02745 ENOG4105F38 ABC transporter, permease EGX53_02750 ENOG4105EG2 ABC transporter, permease EGX53_02775 ENOG4105CHH sulfate transporter EGX53_02785 ENOG41063JG Transcriptional regulator EGX53_02790 ENOG4108YY7 Invasion gene expression up-regulator SirB EGX53_02795 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) EGX53_02820 ENOG4105C5T Phosphoribosyl pyrophosphate synthase EGX53_02825 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria EGX53_02835 ENOG4105C3G gtp-binding protein EGX53_02855 ENOG4105ENX hydrolase EGX53_02865 ENOG4105GR3 Histidine kinase EGX53_02905 ENOG4108WF3 methyltransferase EGX53_02970 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase EGX53_02975 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) EGX53_02985 ENOG41090B9 response to stress EGX53_02990 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) EGX53_02995 ENOG4105CZE histidine utilization repressor EGX53_03040 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family EGX53_03050 ENOG4105BZU Histidine kinase EGX53_03055 ENOG4105EWV Sodium calcium exchanger membrane region EGX53_03060 ENOG4108RS6 transposase EGX53_03065 ENOG4105D5M phosphate starvation-inducible protein EGX53_03080 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD EGX53_03085 ENOG4105CND Glycosyl transferase, family 2 EGX53_03090 ENOG4107BJW polysaccharide deacetylase EGX53_03095 ENOG4108TUY outer membrane protein PgaA EGX53_03100 ENOG4105H1N peptidase, M24 EGX53_03120 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EGX53_03130 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) EGX53_03145 ENOG4107SJW iron permease, FTR1 EGX53_03155 ENOG4105CSV Glutaminase EGX53_03165 ENOG4105MVE transcriptional regulator EGX53_03170 ENOG4105C85 amino acid EGX53_03180 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) EGX53_03220 ENOG4105DJG MaoC domain protein dehydratase EGX53_03225 ENOG4105CYC Transferase EGX53_03230 ENOG4108Q9V regulatoR EGX53_03235 ENOG4105BZU Histidine kinase EGX53_03250 ENOG4105CW0 outer membrane usher protein EGX53_03260 ENOG4108MQF Chaperone EGX53_03275 ENOG4108IJ9 (ABC) transporter EGX53_03280 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component EGX53_03295 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) EGX53_03305 ENOG4105FDP GntR family transcriptional regulator EGX53_03410 ENOG4105ZTC transcriptional activator, Ogr delta EGX53_03415 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EGX53_03470 ENOG4108IRC dna polymerase iii EGX53_03475 ENOG4105DFE Dna adenine methylase EGX53_03485 ENOG4105VZ1 Replication Protein EGX53_03500 ENOG4105ED4 portal protein EGX53_03645 ENOG4105ZTC transcriptional activator, Ogr delta EGX53_03675 ENOG4105WH1 Two component transcriptional regulator luxr family EGX53_03680 ENOG4105XVG cytoplasmic protein EGX53_03685 ENOG4105RA2 Membrane EGX53_03700 ENOG4108T1M outer membrane protein x EGX53_03710 ENOG4105C85 amino acid EGX53_03740 ENOG4105CK7 Sodium proline symporter EGX53_03750 ENOG4105C26 Dehydrogenase EGX53_03765 ENOG4105CDA abc transporter atp-binding protein EGX53_03770 ENOG4105E5Q amino acid AbC transporter EGX53_03775 ENOG4105EAB amino acid AbC transporter EGX53_03785 ENOG4108M9K flagella biosynthesis protein FliZ EGX53_03790 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX53_03795 ENOG4105I03 Flagellin EGX53_03800 ENOG4105DTS flagellar hook-associated EGX53_03805 ENOG4105MQ3 flagellar protein FliS EGX53_03825 ENOG4105DHT Metal Dependent Phosphohydrolase EGX53_03850 ENOG4105VQ0 flagellar hook-basal body complex protein fliE EGX53_03855 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) EGX53_03860 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) EGX53_03865 ENOG41090PJ Flagellar assembly protein EGX53_03870 ENOG4108JIR Flagellum-specific ATP synthase EGX53_03875 ENOG4105GSA Flagellar export protein flij EGX53_03880 ENOG4105WF4 Flagellar hook-length control protein EGX53_03885 ENOG4107ZI8 flagellar basal body-associated protein flil EGX53_03890 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) EGX53_03895 ENOG4105DD5 Flagellar motor switch protein EGX53_03905 ENOG4105CN7 Flagellar biosynthetic protein FliP EGX53_03910 ENOG4105VS8 Flagellar biosynthetic protein fliq EGX53_03915 ENOG4105D19 Role in flagellar biosynthesis (By similarity) EGX53_03925 ENOG4108MGF sugar kinase EGX53_03930 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane EGX53_03935 ENOG4105C2J ABC transporter EGX53_03945 ENOG4105CNN ABC, transporter EGX53_03955 ENOG4105DKT Transcriptional regulator EGX53_03960 ENOG4105DTJ flagellar hook-associated protein EGX53_03965 ENOG4105E1Q flagellar hook-associated protein EGX53_03970 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj EGX53_03985 ENOG4105CGA flagellar basal-body rod protein FlgG EGX53_03990 ENOG4108KPB Flagellar basal-body rod protein FlgF EGX53_03995 ENOG4105BZE flagellar hook protein, FlgE EGX53_04000 ENOG4105W00 Flagellar hook capping protein EGX53_04005 ENOG4108ZC9 flagellar basal-body rod protein flgc EGX53_04010 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) EGX53_04015 ENOG4105CKS Flagella basal body P-ring formation protein flgA EGX53_04020 ENOG4105M9M anti-sigma28 factor FlgM EGX53_04025 ENOG4105QVD Flagella synthesis protein FlgN EGX53_04035 ENOG4105W13 flagellar protein EGX53_04040 ENOG4105D7B Flagellar biosynthesis protein flha EGX53_04045 ENOG4105D00 flagellar biosynthetic protein flhB EGX53_04070 ENOG4105NKT exported protein EGX53_04080 ENOG4105FXM Copper resistance protein EGX53_04085 ENOG41090A1 ferritin EGX53_04090 ENOG4105MPK DNA polymerase III subunit theta EGX53_04100 ENOG4105CUG Oligopeptidase b EGX53_04115 ENOG4105X2V dna damage-inducible protein EGX53_04120 ENOG4105C1J atp-dependent rna helicase EGX53_04135 ENOG4105CRQ synthase (Component I) EGX53_04145 ENOG4105EJQ L-serine dehydratase EGX53_04150 ENOG4107UWN reductase EGX53_04155 ENOG4105EFA 4-hydroxyphenylacetate EGX53_04180 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase EGX53_04185 ENOG4105C26 Dehydrogenase EGX53_04200 ENOG4108V8F Transcriptional regulator, MarR family EGX53_04210 ENOG4105EE5 Membrane protein terC EGX53_04215 ENOG4108EQA pts system EGX53_04220 ENOG4105ETZ PTS System EGX53_04225 ENOG4105F3R pts system mannose fructose sorbose family iid EGX53_04245 ENOG4105BZU Histidine kinase EGX53_04255 ENOG4105DHI Methyltransferase EGX53_04260 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EGX53_04265 ENOG4105VEQ Cold shock protein EGX53_04270 ENOG410610J Protein of unknown function (DUF2627) EGX53_04285 ENOG4105C85 amino acid EGX53_04305 ENOG41064PC EGX53_04320 ENOG4105N4N Protein of unknown function (DUF2766) EGX53_04335 ENOG4105BZ1 (ABC) transporter EGX53_04370 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) EGX53_04385 ENOG4108TSE Transferase EGX53_04390 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit EGX53_04400 ENOG4105CG6 trap dicarboxylate transporter dctm subunit EGX53_04405 ENOG4108KX4 response regulator EGX53_04415 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme EGX53_04435 ENOG4105UQX Mate efflux family protein EGX53_04455 ENOG4105DIA mandelate racemase muconate lactonizing EGX53_04465 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr EGX53_04475 ENOG4105KIR Thiol-disulfide oxidoreductase dcc EGX53_04480 ENOG4105CSP Major Facilitator Superfamily EGX53_04485 ENOG4105TNG K13735 adhesin invasin EGX53_04500 ENOG4105CJB Exodeoxyribonuclease I EGX53_04515 ENOG4105CUB amino acid EGX53_04525 ENOG4107SCQ Iron-containing alcohol dehydrogenase EGX53_04530 ENOG4105C2J ABC transporter EGX53_04535 ENOG4105CNN ABC, transporter EGX53_04540 ENOG4108535 NAD dependent epimerase/dehydratase family EGX53_04555 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) EGX53_04570 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) EGX53_04585 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase EGX53_04595 ENOG4108RS6 transposase EGX53_04600 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) EGX53_04605 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EGX53_04610 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase EGX53_04615 ENOG4105DUU IucA IucC family protein EGX53_04620 ENOG4105CNM Receptor EGX53_04625 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) EGX53_04630 ENOG4105DQ5 transport system permease protein EGX53_04635 ENOG4105TVJ transport system, permease EGX53_04640 ENOG4105E0A ABC, transporter EGX53_04645 ENOG4105DUU IucA IucC family protein EGX53_04655 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) EGX53_04660 ENOG4105DY8 decarboxylase EGX53_04665 ENOG4108819 ferric iron reductase EGX53_04670 ENOG4105EE5 Membrane protein terC EGX53_04675 ENOG4108GAE asmA family EGX53_04690 ENOG4105D1F ATP-binding protein EGX53_04715 ENOG4105E5W Transporter EGX53_04725 ENOG41067MG lrgb family EGX53_04740 ENOG4107GZ4 SanA protein EGX53_04745 ENOG4108HWV )-transporter EGX53_04760 ENOG4105DHF Membrane EGX53_04770 ENOG4105CBP Major Facilitator EGX53_04775 ENOG4105EGI Transcriptional regulator EGX53_04800 ENOG4105ENT Efflux transporter rnd family, mfp subunit EGX53_04805 ENOG4105C19 ABC transporter EGX53_04815 ENOG4105CVM Molybdenum cofactor synthesis domain protein EGX53_04820 ENOG4105D06 uba thif-type nad fad binding protein EGX53_04830 ENOG4105C5H ABC transporter EGX53_04930 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EGX53_04935 ENOG41062T2 Acyl carrier protein EGX53_04945 ENOG4105CHR reductase EGX53_04950 ENOG4108KQ6 Enoyl-CoA hydratase EGX53_04960 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase EGX53_04965 ENOG4105CHR reductase EGX53_04970 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EGX53_04975 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) EGX53_05010 ENOG4108Z0T Part of a sulfur-relay system (By similarity) EGX53_05030 ENOG4105K4P CoA-binding domain protein EGX53_05035 ENOG4108Q67 UPF0319 protein EGX53_05045 ENOG41088T4 Helicase IV EGX53_05050 ENOG410901E Membrane EGX53_05055 ENOG4105EM2 membrane EGX53_05060 ENOG4108RZ1 DNA transformation protein EGX53_05070 ENOG4105UYK outer membrane protein a EGX53_05075 ENOG4108RS6 transposase EGX53_05085 ENOG4105DAN ATP-dependent protease EGX53_05100 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EGX53_05105 ENOG4105WFT During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity) EGX53_05115 ENOG4108Q2G (LipO)protein EGX53_05120 ENOG4105DY2 Paraquat-inducible protein b EGX53_05125 ENOG4105F1S paraquat-inducible protein a EGX53_05130 ENOG4105C5H ABC transporter EGX53_05140 ENOG4105QVC MOSC domain-containing protein EGX53_05145 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) EGX53_05155 ENOG4105CD8 aminopeptidase N EGX53_05175 ENOG4105CGF Aromatic amino acid aminotransferase EGX53_05180 ENOG4105C5X domain protein EGX53_05185 ENOG4105EAQ (twin-arginine translocation) pathway signal EGX53_05190 ENOG4105DIT ErfK YbiS YcfS YnhG family protein EGX53_05200 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) EGX53_05205 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) EGX53_05210 ENOG4106371 Methyltransferase EGX53_05220 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups EGX53_05235 ENOG4105W49 UPF0434 protein EGX53_05240 ENOG4105VEQ Cold shock protein EGX53_05250 ENOG4105E32 cytoplasmic protein EGX53_05280 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) EGX53_05310 ENOG4105HDK L-asparaginase EGX53_05315 ENOG4105DDY UPF0142 protein ycaO EGX53_05320 ENOG4105TMB Formate nitrite transporter EGX53_05325 ENOG4105C6N Formate acetyltransferase EGX53_05335 ENOG4105F1A Pyruvate formate-lyase EGX53_05350 ENOG4105D1H recombination factor protein RarA EGX53_05360 ENOG4105CNU cell division protein FtsK EGX53_05365 ENOG4105EW9 transcriptional regulator AsnC family EGX53_05370 ENOG4105C3M thioredoxin reductase EGX53_05375 ENOG4108JJ9 ABC, transporter EGX53_05380 ENOG4108JJ8 (ABC) transporter EGX53_05390 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) EGX53_05395 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EGX53_05410 ENOG4105VEQ Cold shock protein EGX53_05420 ENOG4105DJY efflux transporter, rnd family, mfp subunit EGX53_05425 ENOG4108MJ5 VirK protein EGX53_05430 ENOG4105CPB ATP-dependent endonuclease of the OLD family EGX53_05435 ENOG4105DWU Membrane EGX53_05445 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EGX53_05450 ENOG4105C7K acetolactate synthase EGX53_05455 ENOG4105C5W Aldolase EGX53_05460 ENOG4105CGD Nad-dependent epimerase dehydratase EGX53_05465 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase EGX53_05470 ENOG41064MM (LipO)protein EGX53_05475 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) EGX53_05480 ENOG4105E5Z arginine transporter ATP-binding subunit EGX53_05485 ENOG4106PMH Extracellular solute-binding protein family 3 EGX53_05490 ENOG4105GBT ABC transporter EGX53_05495 ENOG4105DMR ABC, transporter EGX53_05500 ENOG4108I0N Transporter, RarD family, DMT superfamily protein EGX53_05505 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) EGX53_05510 ENOG410642S Nicotianamine synthase protein EGX53_05515 ENOG4105E0A ABC, transporter EGX53_05520 ENOG4108I9K permease protein EGX53_05540 ENOG4106TNF Periplasmic binding protein EGX53_05550 ENOG4105RBQ inner membrane protein ybjO EGX53_05555 ENOG4105D38 putrescine abc transporter EGX53_05560 ENOG4105F38 ABC transporter, permease EGX53_05565 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EGX53_05570 ENOG4107RUE extracellular solute-binding protein family 1 EGX53_05575 ENOG4108RMJ sensory transduction regulator EGX53_05585 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress EGX53_05590 ENOG41090BQ Glutaredoxin EGX53_05595 ENOG4105D0C transport protein EGX53_05610 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase EGX53_05615 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) EGX53_05620 ENOG4107FB0 transcriptional regulator DeoR family EGX53_05625 ENOG4105C44 Serine transporter EGX53_05630 ENOG4105DZ1 carboxypeptidase EGX53_05635 ENOG4108UMI ABC transporter, permease EGX53_05645 ENOG4105D01 (LipO)protein EGX53_05660 ENOG4108TGY Glutathione S-transferase EGX53_05665 ENOG4105D05 Receptor EGX53_05675 ENOG4105EHG Permease protein EGX53_05685 ENOG4108IQI permease EGX53_05690 ENOG4105DUM transcriptional regulator, lysR family EGX53_05695 ENOG4105HMI Membrane EGX53_05705 ENOG4108D1K outer membrane usher protein EGX53_05710 ENOG4108UIF Chaperone EGX53_05725 ENOG4108SGD regulatory protein EGX53_05730 ENOG4105DM4 PTS System EGX53_05735 ENOG4105DE4 1-phosphofructokinase EGX53_05740 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein EGX53_05750 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane EGX53_05755 ENOG4105C2J ABC transporter EGX53_05765 ENOG4105E66 phosphoriboisomerase A EGX53_05775 ENOG4105C26 Dehydrogenase EGX53_05790 ENOG4105CHR reductase EGX53_05795 ENOG4105KRS Proteinase inhibitor EGX53_05810 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) EGX53_05815 ENOG4105DEI Mannitol dehydrogenase EGX53_05820 ENOG4107YCY Transcriptional regulator EGX53_05830 ENOG4105CKI cobalamin synthesis protein EGX53_05835 ENOG41076MN Phosphoesterase, PA-phosphatase related EGX53_05840 ENOG4107TT5 NLP P60 protein EGX53_05845 ENOG4105CXC rtn protein EGX53_05850 ENOG4105E43 Extracellular solute-binding protein, family 5 EGX53_05855 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component EGX53_05860 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component EGX53_05865 ENOG4108JQ5 ABC transporter EGX53_05870 ENOG4105HG6 EGX53_05875 ENOG4105C2C drug resistance transporter, Bcr CflA EGX53_05880 ENOG4105I08 Pseudouridine synthase EGX53_05885 ENOG4105CFI type iii restriction protein res subunit EGX53_05900 ENOG4105PAN UPF0352 protein EGX53_05905 ENOG4105E68 Sulfatase EGX53_05950 ENOG4105CS2 ec 3.2.1.21 EGX53_05955 ENOG4108Q3X Transcriptional regulator EGX53_05975 ENOG4108T86 baseplate J family protein EGX53_06015 ENOG4105TKZ Tail Sheath EGX53_06035 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) EGX53_06040 ENOG4105MVE transcriptional regulator EGX53_06050 ENOG4105G63 Type III effector Hrp-dependent EGX53_06055 ENOG4105HRS Antitermination protein EGX53_06065 ENOG4105Y50 Virulence Protein EGX53_06080 ENOG4105C8Q Methyl-accepting chemotaxis EGX53_06090 ENOG4105CT4 transporter EGX53_06095 ENOG4107R6D beta-lactam binding protein AmpH EGX53_06120 ENOG4105FCK Membrane EGX53_06125 ENOG4106UW1 Major Facilitator superfamily EGX53_06130 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC EGX53_06135 ENOG41068CG regulatoR EGX53_06140 ENOG4105BZU Histidine kinase EGX53_06145 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EGX53_06155 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EGX53_06160 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EGX53_06165 ENOG4105XPH Ferredoxin EGX53_06185 ENOG4105E0U tyrosine-specific transport protein EGX53_06190 ENOG4108UII YfaZ family EGX53_06195 ENOG4105CH6 catalase EGX53_06200 ENOG4105DVT helicase EGX53_06210 ENOG4105FDR Membrane EGX53_06220 ENOG4105CXN decarboxylase EGX53_06225 ENOG4105D5Q Arginine ornithine antiporter EGX53_06230 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component EGX53_06235 ENOG4108IJ8 ABC transporter EGX53_06240 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component EGX53_06245 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system EGX53_06250 ENOG4105KHC sulfurtransferase EGX53_06265 ENOG4108IV0 ABC, transporter EGX53_06270 ENOG4108JJB ABC transporter EGX53_06275 ENOG4105CNN ABC, transporter EGX53_06280 ENOG4105C32 Amino acid ABC transporter (Permease) EGX53_06290 ENOG4108W15 Protein of unknown function (DUF1456) EGX53_06305 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein EGX53_06315 ENOG4105Y3U Transglycosylase-associated protein EGX53_06325 ENOG4105N1F Hnh endonuclease EGX53_06335 ENOG4105CXG d-lactate dehydrogenase EGX53_06340 ENOG41061WM D-Alanyl-D-Alanine EGX53_06350 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) EGX53_06360 ENOG4108RS6 transposase EGX53_06405 ENOG4105C1J atp-dependent rna helicase EGX53_06410 ENOG4107MVR Transcriptional regulator EGX53_06420 ENOG4105CJ1 ABC, transporter EGX53_06425 ENOG4107QWP ABC-2 type transporter EGX53_06430 ENOG4107QWP ABC-2 type transporter EGX53_06450 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EGX53_06460 ENOG4105BZU Histidine kinase EGX53_06470 ENOG4105EAA nucleoside EGX53_06475 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) EGX53_06485 ENOG4105CN8 Transcriptional regulator EGX53_06490 ENOG4105C94 Transporter EGX53_06510 ENOG4105HFZ Membrane EGX53_06515 ENOG4108ZAF Molybdopterin EGX53_06520 ENOG4105M00 molybdopterin converting factor, subunit 1 EGX53_06530 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) EGX53_06535 ENOG4105CHW UPF0052 protein EGX53_06540 ENOG4105VYA Uncharacterized conserved protein (DUF2132) EGX53_06550 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) EGX53_06555 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) EGX53_06560 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) EGX53_06585 ENOG4108K4B hydrolase EGX53_06595 ENOG4105E0C molybdate abc transporter EGX53_06600 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein EGX53_06605 ENOG410680R Protein of unknown function (DUF2592) EGX53_06610 ENOG4105F4R Transcriptional regulator mode EGX53_06615 ENOG4105DKW ABC transporter EGX53_06625 ENOG4105CMR udp-glucose 4-epimerase EGX53_06630 ENOG4105F0Z galactose-1-phosphate uridylyltransferase EGX53_06640 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) EGX53_06655 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EGX53_06660 ENOG4105PGM cation diffusion facilitator family transporter EGX53_06665 ENOG4106Z1T Nicotinamide Mononucleotide Transporter EGX53_06705 ENOG4105UFD tol-pal system protein YbgF EGX53_06710 ENOG4105KCK Peptidoglycan-associated lipoprotein EGX53_06720 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA EGX53_06720 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA EGX53_06725 ENOG4105M8F Biopolymer transport protein exbD tolR EGX53_06730 ENOG4105E02 MotA TolQ exbB proton channel EGX53_06735 ENOG4107YD3 Thioesterase EGX53_06740 ENOG4105KJB cyd operon protein YbgE EGX53_06750 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii EGX53_06755 ENOG4105C4M (Ubiquinol oxidase) subunit I EGX53_06760 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha EGX53_06770 ENOG4105C7S Dehydrogenase EGX53_06775 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 EGX53_06780 ENOG4105E33 succinate dehydrogenase EGX53_06790 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein EGX53_06795 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit EGX53_06800 ENOG4105BZN citrate synthase EGX53_06810 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) EGX53_06815 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) EGX53_06820 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EGX53_06830 ENOG4108Z1B Cyclase dehydrase EGX53_06845 ENOG4105DFP Integrase EGX53_06865 ENOG4105EV9 Alpha Beta Hydrolase EGX53_06870 ENOG4105NNH LexA regulated protein EGX53_06880 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) EGX53_06885 ENOG41090R7 Ferric uptake EGX53_06905 ENOG4108RS6 transposase EGX53_06915 ENOG4105CI1 PTS System EGX53_06925 ENOG4105CE4 GlcNAc 6-P deacetylase EGX53_06930 ENOG4105E2R ROK family EGX53_06935 ENOG4105D4U had-superfamily hydrolase, subfamily iia EGX53_06940 ENOG4105CAQ asparagine synthetase EGX53_06980 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family EGX53_06990 ENOG4105C9A Phoh family EGX53_07000 ENOG4108JU5 Magnesium and cobalt efflux protein EGX53_07005 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) EGX53_07010 ENOG4107RP9 extracellular solute-binding protein, family 3 EGX53_07015 ENOG4105EAD ABC transporter EGX53_07020 ENOG4105DRP amino acid AbC transporter EGX53_07025 ENOG4105CDA abc transporter atp-binding protein EGX53_07030 ENOG4107PAI alpha helical protein EGX53_07045 ENOG4105DJF DNA polymerase III, delta' subunit EGX53_07055 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) EGX53_07065 ENOG4105CJN penicillin-binding protein EGX53_07070 ENOG4105CNI cell division protein FtsW EGX53_07075 ENOG4105K6T rare lipoprotein A EGX53_07080 ENOG4105DZ1 carboxypeptidase EGX53_07105 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) EGX53_07110 ENOG4107Z6W Protein CrcB homolog EGX53_07115 ENOG4105VEQ Cold shock protein EGX53_07125 ENOG4108N8T regulatoR EGX53_07150 ENOG4108JJ7 ABC transporter EGX53_07160 ENOG4105DH8 myo-inositol catabolism EGX53_07170 ENOG4105EDK PfkB domain protein EGX53_07175 ENOG4105CK5 oxidoreductase EGX53_07180 ENOG4105CNN ABC, transporter EGX53_07185 ENOG4105C2J ABC transporter EGX53_07190 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator EGX53_07200 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) EGX53_07205 ENOG4105C26 Dehydrogenase EGX53_07220 ENOG4105DN3 alpha-2-macroglobulin domain protein EGX53_07225 ENOG4108JQB penicillin-binding protein 1C EGX53_07230 ENOG4105HVQ Regulatory factor of maltose metabolism EGX53_07250 ENOG4108WC9 type VI secretion system effector, hcp1 family EGX53_07280 ENOG4105EZE Cupin 4 family protein EGX53_07295 ENOG4105FE9 pseudouridine synthase EGX53_07310 ENOG4107QK4 glycoside hydrolase, family 3 domain protein EGX53_07325 ENOG4107SET aldo keto reductase EGX53_07330 ENOG4105EQ2 LysR family Transcriptional regulator EGX53_07345 ENOG41077RS Phosphatase EGX53_07350 ENOG4105E8V Alpha Beta Hydrolase Fold protein EGX53_07360 ENOG4108HPI phosphatidate Cytidylyltransferase EGX53_07365 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase EGX53_07380 ENOG4108KU3 Integrase EGX53_07405 ENOG4105UZW Tail fiber assembly protein EGX53_07490 ENOG4105Y50 Virulence Protein EGX53_07500 ENOG4105PTU response to oxidative stress EGX53_07560 ENOG4105TKZ Tail Sheath EGX53_07595 ENOG4108KU3 Integrase EGX53_07620 ENOG4108XS9 dna repair protein EGX53_07625 ENOG4106H6R UPF0380 protein EGX53_07650 ENOG4108MXD gtp-binding protein EGX53_07705 ENOG4105DFP Integrase EGX53_07710 ENOG4105DFP Integrase EGX53_07725 ENOG4105WQ3 Rna-binding protein EGX53_07735 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EGX53_07750 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) EGX53_07755 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit EGX53_07760 ENOG4105CV6 ABC transporter, permease EGX53_07765 ENOG4108I0Y (ABC) transporter EGX53_07770 ENOG4108UJV acyl-CoA thioesterase i EGX53_07775 ENOG4105E1F short-chain dehydrogenase reductase EGX53_07780 ENOG4107QR8 Thioredoxin EGX53_07785 ENOG4107QX8 SPFH domain, Band 7 family protein EGX53_07790 ENOG4105G5H Membrane EGX53_07795 ENOG4108Z6Z Transcriptional regulator EGX53_07800 ENOG4105C59 p-type ATPase EGX53_07805 ENOG4105MBR gumn family EGX53_07810 ENOG4108Z66 YbaK ebsC protein EGX53_07820 ENOG4105CGH 5'-nucleotidase EGX53_07825 ENOG4105CGH 5'-nucleotidase EGX53_07835 ENOG4108RS6 transposase EGX53_07845 ENOG4105CKD glutathione-regulated potassium-efflux system protein EGX53_07850 ENOG4107RE1 Inosine-guanosine kinase EGX53_07855 ENOG4108QY5 Ferric enterobactin transport protein EGX53_07865 ENOG4105DMT epimerase dehydratase EGX53_07875 ENOG4105CJT Mannose-1-phosphate guanylyltransferase EGX53_07880 ENOG4105C30 Nad-dependent epimerase dehydratase EGX53_07885 ENOG4105C0K Gdp-mannose 4,6-dehydratase EGX53_07890 ENOG4108TJN glycosyl transferase group 1 EGX53_07900 ENOG41081E6 Inherit from COG: Polysaccharide biosynthesis protein EGX53_07910 ENOG4108SMP Nad-dependent epimerase dehydratase EGX53_07915 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase EGX53_07920 ENOG4105FAW cDP-glucose 4,6-dehydratase EGX53_07925 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase EGX53_07930 ENOG4108EX3 reductase EGX53_07960 ENOG4107QMP dna polymerase iii subunits gamma and tau EGX53_07970 ENOG4105WD1 Membrane EGX53_07980 ENOG4106428 Protein of unknown function (DUF2496) EGX53_07985 ENOG4105EGS Mechanosensitive ion channel EGX53_07990 ENOG41090EX DsrE family EGX53_07995 ENOG4108IG5 Transcriptional regulator EGX53_08000 ENOG4105C1P efflux transporter, rnd family, mfp subunit EGX53_08005 ENOG4105BZS acriflavin resistance protein EGX53_08015 ENOG4108RS6 transposase EGX53_08025 ENOG4105YK5 50S ribosomal protein L36 EGX53_08035 ENOG4108UKR Biofilm formation regulator YbaJ EGX53_08040 ENOG4105KF5 hemolysin expression-modulating protein EGX53_08050 ENOG41080UX Methyltransferase EGX53_08055 ENOG4108MNP Glycoprotein polysaccharide metabolism EGX53_08060 ENOG4105C29 acyl-CoA thioesterase EGX53_08065 ENOG4105BZU Histidine kinase EGX53_08070 ENOG4108YZA Nitrogen regulatory protein pii EGX53_08075 ENOG4105BZ1 (ABC) transporter EGX53_08080 ENOG4105BZ1 (ABC) transporter EGX53_08085 ENOG4108XM1 transcriptional regulator AsnC family EGX53_08090 ENOG4105C6T cysteine synthase EGX53_08100 ENOG4108NFA extracellular solute-binding protein EGX53_08110 ENOG4108TGP Thioesterase superfamily protein EGX53_08115 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein EGX53_08120 ENOG4105EIN peptidylprolyl cis-trans isomerase EGX53_08125 ENOG4105K70 DNA-binding protein EGX53_08130 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) EGX53_08155 ENOG4105M85 Bola protein EGX53_08160 ENOG4105IEY (LipO)protein EGX53_08165 ENOG4105EYM Major Facilitator superfamily EGX53_08175 ENOG4105E2S oxidase) subunit II EGX53_08180 ENOG4105BZ9 Cytochrome C oxidase, subunit I EGX53_08185 ENOG4105CCU oxidase (Subunit III) EGX53_08190 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) EGX53_08200 ENOG4107RDB Major Facilitator EGX53_08215 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) EGX53_08220 ENOG4107S0N DJ-1 family EGX53_08235 ENOG4105CTB Polyprenyl synthetase EGX53_08245 ENOG4108ZAI phosphatidylglycerophosphatase a EGX53_08250 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) EGX53_08265 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) EGX53_08285 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EGX53_08290 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) EGX53_08295 ENOG4105VIE preprotein translocase, subunit YajC EGX53_08315 ENOG4105D3R alkyl hydroperoxide reductase EGX53_08330 ENOG4107FW0 short-chain dehydrogenase reductase EGX53_08340 ENOG4107R28 alpha amylase, catalytic region EGX53_08345 ENOG4105C85 amino acid EGX53_08350 ENOG4105CWM branched-chain amino acid transport system II carrier protein EGX53_08360 ENOG4105BZU Histidine kinase EGX53_08365 ENOG4105CK6 Two component transcriptional regulator (Winged helix family EGX53_08370 ENOG4107RH8 nuclease SbcCD subunit D EGX53_08375 ENOG4105EYH Exonuclease EGX53_08380 ENOG4105DKQ ROK family EGX53_08410 ENOG4105F2W methyltransferase EGX53_08460 ENOG4108KB2 LysR family Transcriptional regulator EGX53_08465 ENOG4105CIN aminoacyl-histidine dipeptidase EGX53_08485 ENOG4105CJ2 (LipO)protein EGX53_08505 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) EGX53_08510 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) EGX53_08515 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) EGX53_08525 ENOG4105F7V ErfK ybiS ycfS ynhG family protein EGX53_08530 ENOG4105E7A Glutamine amidotransferase EGX53_08540 ENOG4107QPN acyl-Coa dehydrogenase EGX53_08550 ENOG4106YJS accessory processing protein EGX53_08570 ENOG4108RS6 transposase EGX53_08600 ENOG4105CHM Aminotransferase EGX53_08615 ENOG4105C5R Aminotransferase EGX53_08625 ENOG4105E5Q amino acid AbC transporter EGX53_08635 ENOG4105F87 Dehydratase EGX53_08665 ENOG4105EQ0 Major Facilitator superfamily EGX53_08670 ENOG4108UMN azlc family EGX53_08675 ENOG4105ZED uncharacterized protein ygaH EGX53_08680 ENOG4105NTK Transcriptional repressor Mpra EGX53_08685 ENOG4105CW7 secretion protein, HlyD family EGX53_08690 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX53_08695 ENOG4105EIB trna rrna methyltransferase EGX53_08700 ENOG4105K63 Thioredoxin EGX53_08710 ENOG4105CD5 CoA-binding domain protein EGX53_08715 ENOG4105JIM Phosphatidylserine synthase EGX53_08720 ENOG4105T42 (LipO)protein EGX53_08760 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EGX53_08765 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase EGX53_08770 ENOG4105C34 Pseudouridine synthase EGX53_08780 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane EGX53_08785 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA EGX53_08800 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) EGX53_08805 ENOG4108NEV two component transcriptional regulator, LytTR family EGX53_08810 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter EGX53_08815 ENOG4108NE3 Salt-induced outer membrane protein EGX53_08840 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY EGX53_08845 ENOG4106KVJ cytochrome C assembly protein EGX53_08850 ENOG4108JU6 CBS domain protein EGX53_08865 ENOG4105W39 Membrane EGX53_08870 ENOG4107VXZ Hydrolase EGX53_08900 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) EGX53_08945 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) EGX53_08950 ENOG4108IUS Transketolase EGX53_08955 ENOG4108HHA Transketolase EGX53_08960 ENOG4105CNN ABC, transporter EGX53_08965 ENOG4105C2J ABC transporter EGX53_08985 ENOG4108XVM Cytochrome b(562) EGX53_08990 ENOG4105CPW cytochrome b561 EGX53_08995 ENOG4108NEM leader-binding protein dmsD EGX53_09000 ENOG4107KGK dmso reductase anchor subunit EGX53_09005 ENOG4105QAX Iron-sulfur EGX53_09010 ENOG4107QY8 reductase EGX53_09015 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase EGX53_09020 ENOG4105E98 transcriptional regulator DeoR family EGX53_09030 ENOG4105C2J ABC transporter EGX53_09035 ENOG4105CNN ABC, transporter EGX53_09040 ENOG4105F5R ABC transporter EGX53_09045 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase EGX53_09050 ENOG4105CMG Carbohydrate kinase EGX53_09055 ENOG4107GFK fumarate EGX53_09065 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EGX53_09075 ENOG4105D05 Receptor EGX53_09085 ENOG4105CA0 peroxidase EGX53_09090 ENOG4105E89 ABC transporter EGX53_09115 ENOG4105DKT Transcriptional regulator EGX53_09125 ENOG4105CMT Dihydroxyacetone kinase EGX53_09130 ENOG4105CHR reductase EGX53_09135 ENOG4105CPQ Dehydrogenase EGX53_09140 ENOG4108YZG isomerase EGX53_09150 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX53_09155 ENOG4108K5P (LipO)protein EGX53_09190 ENOG4105N0Z inner membrane protein ygbE EGX53_09195 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) EGX53_09245 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase EGX53_09250 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) EGX53_09270 ENOG4105DXN mazG family EGX53_09275 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EGX53_09280 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) EGX53_09290 ENOG4105BZU Histidine kinase EGX53_09295 ENOG4105C0H protease EGX53_09315 ENOG4105EN6 Membrane EGX53_09335 ENOG4105S6R Iron-hydroxamate transporter permease subunit EGX53_09340 ENOG4105J76 Periplasmic binding protein EGX53_09345 ENOG4105E0A ABC, transporter EGX53_09350 ENOG4105BZ4 penicillin-binding protein EGX53_09355 ENOG4105CQ7 ATP-dependent helicase EGX53_09360 ENOG4107XID 2'-5' rna ligase EGX53_09375 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters EGX53_09385 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) EGX53_09390 ENOG4105DJ0 Poly(A) Polymerase EGX53_09395 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase EGX53_09415 ENOG4107BJW polysaccharide deacetylase EGX53_09420 ENOG4105E3A (ABC) transporter EGX53_09425 ENOG4105DA5 (ABC) transporter EGX53_09430 ENOG41077A9 carbonic anhydrase EGX53_09435 ENOG4108UGV hypoxanthine phosphoribosyltransferase EGX53_09440 ENOG4105E3B Multicopper oxidase EGX53_09445 ENOG4108ZRK uncharacterized protein yacC EGX53_09460 ENOG4105RPH Inner membrane protein YddG EGX53_09470 ENOG4107QIJ Aconitate hydratase 2 EGX53_09485 ENOG4108RS6 transposase EGX53_09490 ENOG4107QN2 dihydrolipoyl dehydrogenase EGX53_09495 ENOG4107QSN dihydrolipoamide acetyltransferase EGX53_09500 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) EGX53_09505 ENOG41073TP transcriptional regulator EGX53_09515 ENOG4105C85 amino acid EGX53_09520 ENOG4106A72 regulatory protein AmpE EGX53_09525 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase EGX53_09530 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase EGX53_09535 ENOG4108ZUW Major pilin subunit EGX53_09540 ENOG4107QHF type ii secretion system protein e EGX53_09545 ENOG4105D7Q type ii secretion system EGX53_09560 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) EGX53_09575 ENOG4108RS6 transposase EGX53_09585 ENOG4105M6F mutator MutT protein EGX53_09615 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) EGX53_09620 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) EGX53_09625 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) EGX53_09645 ENOG4105CNI cell division protein FtsW EGX53_09660 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) EGX53_09665 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) EGX53_09670 ENOG4105CJN penicillin-binding protein EGX53_09675 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) EGX53_09695 ENOG4108RNS Exports L-alanine (By similarity) EGX53_09700 ENOG4107B7Y DNA-binding transcriptional regulator FruR EGX53_09710 ENOG4108ZP8 Acetolactate synthase small subunit EGX53_09715 ENOG4105C7K acetolactate synthase EGX53_09725 ENOG4108IQE Amp-dependent synthetase and ligase EGX53_09735 ENOG41064T2 transcriptional regulator, lysR family EGX53_09750 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EGX53_09765 ENOG4105S8Q sugar efflux transporter EGX53_09780 ENOG4105DP9 ABC transporter EGX53_09785 ENOG4106SMU thiamine transporter membrane protein EGX53_09795 ENOG4108KF1 Membrane EGX53_09800 ENOG4105CQ2 DNA polymerase EGX53_09855 ENOG4105CS6 Rhs element vgr protein EGX53_09860 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EGX53_09905 ENOG4105D3G Pseudouridine synthase EGX53_09910 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) EGX53_09920 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) EGX53_09960 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) EGX53_09970 ENOG4105DWK Membrane EGX53_09975 ENOG4108NIW Leucine export protein LeuE EGX53_09980 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain EGX53_09985 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain EGX53_10005 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase EGX53_10020 ENOG4105DTN riboflavin biosynthesis protein ribF EGX53_10040 ENOG41063Z6 transcriptional regulator, lysR family EGX53_10060 ENOG4106HK8 GPR1 FUN34 yaaH family protein EGX53_10075 ENOG4108RIR Molybdenum cofactor biosynthesis protein EGX53_10115 ENOG41065U4 response regulator EGX53_10120 ENOG4108RH0 Crea protein EGX53_10130 ENOG4105UEI Transcriptional Regulator AraC Family EGX53_10145 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) EGX53_10150 ENOG4107SC1 transglycosylase EGX53_10165 ENOG4108KHX Diguanylate cyclase EGX53_10170 ENOG41090EK ompa motb domain protein EGX53_10175 ENOG4105C5H ABC transporter EGX53_10185 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase EGX53_10190 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) EGX53_10195 ENOG4105EAC phosphoserine phosphatase EGX53_10200 ENOG41062Z9 Membrane EGX53_10220 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) EGX53_10225 ENOG4105D9N nucleoside EGX53_10230 ENOG4105EYA deoxyribonuclease EGX53_10235 ENOG4108NRW Phospholipase, patatin family EGX53_10245 ENOG4105K3G Periplasmic Protein EGX53_10255 ENOG4105KEG ribosomal-protein-alanine acetyltransferase EGX53_10260 ENOG4108WPU DNA polymerase III subunit psi EGX53_10285 ENOG4105YBH Protein of unknown function (DUF1435) EGX53_10290 ENOG4105BZU Histidine kinase EGX53_10315 ENOG4105BZS acriflavin resistance protein EGX53_10320 ENOG410624X efflux transporter, rnd family, mfp subunit EGX53_10340 ENOG4105DKP glycosyl transferase, family 9 EGX53_10350 ENOG4105DKT Transcriptional regulator EGX53_10390 ENOG4105RI1 glycoprotein receptor EGX53_10395 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) EGX53_10400 ENOG4105DM4 PTS System EGX53_10405 ENOG4108YRF PTS System EGX53_10410 ENOG4108XCZ PTS System EGX53_10415 ENOG4106R3P AraC family transcriptional regulator EGX53_10425 ENOG4108M3P Membrane EGX53_10480 ENOG4105DZR Type I site-specific deoxyribonuclease EGX53_10500 ENOG4108K5H permease YjgP YjgQ family protein EGX53_10505 ENOG4108M8S permease YjgP YjgQ family protein EGX53_10515 ENOG4105MYG DNA polymerase iii, chi subunit EGX53_10525 ENOG4108MJ3 acetyltransferase EGX53_10530 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) EGX53_10540 ENOG4105XEP YhcH YjgK YiaL family protein EGX53_10550 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EGX53_10555 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EGX53_10560 ENOG4105C3U ABC transporter EGX53_10565 ENOG4108JQ7 (ABC) transporter EGX53_10570 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase EGX53_10575 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) EGX53_10585 ENOG4107RJJ Transcriptional regulator EGX53_10590 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG EGX53_10595 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH EGX53_10600 ENOG4105EKV Phosphonate metabolism protein EGX53_10605 ENOG4105FT8 Phosphonate metabolism EGX53_10610 ENOG4105ENV phosphonate C-P lyase system protein PhnK EGX53_10615 ENOG4105HRV phosphonate c-p lyase system protein phnl EGX53_10620 ENOG4105FD8 phosphonate metabolism protein PhnM EGX53_10625 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) EGX53_10630 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein EGX53_10635 ENOG4105K4T epimerase EGX53_10655 ENOG4105DRS transport system, permease EGX53_10660 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component EGX53_10685 ENOG4108YYD acetyltransferase EGX53_10690 ENOG4105XPQ lipid carrier protein EGX53_10700 ENOG4105CFP Peptidase U32 EGX53_10705 ENOG4106RZ4 Peptidase U32 EGX53_10710 ENOG4105ENJ RND efflux system, outer membrane lipoprotein EGX53_10715 ENOG4105BZS acriflavin resistance protein EGX53_10725 ENOG4105DEN Luciferase family EGX53_10745 ENOG4105C1J atp-dependent rna helicase EGX53_10785 ENOG4105CHV Transcription elongation factor NusA EGX53_10815 ENOG4105EEI dihydropteroate synthase EGX53_10820 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) EGX53_10830 ENOG4105HBR Rna-binding protein EGX53_10835 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) EGX53_10840 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase EGX53_10910 ENOG4105QYV Membrane EGX53_10925 ENOG4105EAH synthase EGX53_10935 ENOG4105HVQ Regulatory factor of maltose metabolism EGX53_10960 ENOG4105DFU Cell wall formation (By similarity) EGX53_10970 ENOG4105F0N pyrophosphate phospho-hydrolase EGX53_10975 ENOG4108ZHD aig2 family EGX53_10980 ENOG4105MA0 exported protein EGX53_10985 ENOG4105CFU surface antigen EGX53_10995 ENOG4105C37 (CBS) domain EGX53_11000 ENOG41061GZ Protein of unknown function (DUF1107) EGX53_11005 ENOG4108UUE Transcriptional regulator EGX53_11010 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase EGX53_11015 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic EGX53_11025 ENOG4108V1T peptidylprolyl cis-trans isomerase EGX53_11030 ENOG4105FHY Opacity-associated protein A EGX53_11045 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) EGX53_11055 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) EGX53_11065 ENOG4108MXZ Esterase EGX53_11070 ENOG4105WSB biofilm stress and motility protein A EGX53_11075 ENOG4105CSU acyl-Coa dehydrogenase EGX53_11080 ENOG4105C2N RNA methyltransferase TrmH family group 3 EGX53_11085 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) EGX53_11105 ENOG4105EPW hflc protein EGX53_11110 ENOG4107QJR hflk protein EGX53_11115 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) EGX53_11135 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase EGX53_11140 ENOG4105K8N protein family UPF0079, ATPase EGX53_11145 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) EGX53_11150 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) EGX53_11195 ENOG4105EGS Mechanosensitive ion channel EGX53_11225 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) EGX53_11230 ENOG4105KPY Small multidrug resistance protein EGX53_11240 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein EGX53_11245 ENOG4108ZVF (LipO)protein EGX53_11275 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter EGX53_11290 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) EGX53_11295 ENOG4108RC0 Electron transport protein EGX53_11300 ENOG4105BZ8 glutamate synthase EGX53_11310 ENOG4108SIC Transcriptional regulator EGX53_11380 ENOG4105C0A alcohol dehydrogenase EGX53_11390 ENOG4108UUM single-stranded DNA-binding protein EGX53_11400 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) EGX53_11405 ENOG4105MSB protein, conserved in bacteria EGX53_11410 ENOG4105CGF Aromatic amino acid aminotransferase EGX53_11415 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) EGX53_11420 ENOG4105CDU Replicative dna helicase EGX53_11425 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein EGX53_11430 ENOG4105P4Z Phage shock protein G EGX53_11435 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EGX53_11440 ENOG4105MYN Zinc uptake regulation protein EGX53_11450 ENOG41080IJ Diacylglycerol kinase EGX53_11505 ENOG4108S1B Periplasmic chaperone protein EGX53_11565 ENOG4105DAX Pfam:DUF2983 EGX53_11585 ENOG4105D4P Coproporphyrinogen iii oxidase EGX53_11590 ENOG41090JE Utilization Protein EGX53_11600 ENOG4107F3C Hemin uptake protein EGX53_11605 ENOG4107ENK receptor EGX53_11610 ENOG4106QJH hemin transport protein EGX53_11615 ENOG4107R4I Periplasmic binding protein EGX53_11620 ENOG4105EHG Permease protein EGX53_11630 ENOG4105C28 cystathionine EGX53_11635 ENOG4105C44 Serine transporter EGX53_11640 ENOG4105EQ2 LysR family Transcriptional regulator EGX53_11645 ENOG4105KSU Redox protein EGX53_11650 ENOG41066VF YeeE YedE family protein EGX53_11655 ENOG4108IUF type iii secretion EGX53_11660 ENOG4108TN6 type iii secretion EGX53_11665 ENOG41083GP type iii secretion EGX53_11670 ENOG4108HHI Type III secretion system protein EGX53_11690 ENOG4108JIR Flagellum-specific ATP synthase EGX53_11755 ENOG4105BZU Histidine kinase EGX53_11760 ENOG4105WH1 Two component transcriptional regulator luxr family EGX53_11765 ENOG4105CK2 sodium dicarboxylate symporter EGX53_11775 ENOG41062QD Membrane EGX53_11830 ENOG4108RR8 protoporphyrinogen oxidase EGX53_11835 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) EGX53_11840 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein EGX53_11860 ENOG4107QK7 reductase EGX53_11870 ENOG4105MDZ Transcriptional activator rfaH EGX53_11875 ENOG4105D52 delta-aminolevulinic acid dehydratase EGX53_11885 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) EGX53_11895 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) EGX53_11905 ENOG4105JC1 sterol-binding domain protein EGX53_11915 ENOG4105CGY Dna recombination protein EGX53_11920 ENOG4108KF1 Membrane EGX53_11935 ENOG4108I5U Uridine phosphorylase EGX53_11940 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) EGX53_11950 ENOG4105DZ2 Transcriptional regulator EGX53_11955 ENOG4105EMK carboxylate amino acid amine transporter EGX53_11970 ENOG4105RK9 auxin efflux carrier EGX53_11975 ENOG4107T6V glycerophosphoryl diester phosphodiesterase EGX53_12035 ENOG4108IV0 ABC, transporter EGX53_12040 ENOG4105C0Z ABC transporter EGX53_12045 ENOG4105CF8 branched-chain amino acid ABC transporter, permease EGX53_12050 ENOG4105C32 Amino acid ABC transporter (Permease) EGX53_12055 ENOG4105CP9 extracellular ligand-binding receptor EGX53_12060 ENOG4105U59 -acetyltransferase EGX53_12070 ENOG4105CRP Part of the ABC transporter FtsEX involved in EGX53_12075 ENOG4105CAK Cell division ATP-binding protein ftsE EGX53_12080 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EGX53_12080 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) EGX53_12090 ENOG4106H78 methyltransferase EGX53_12095 ENOG4105MG3 Membrane EGX53_12110 ENOG4107FS9 Membrane EGX53_12125 ENOG4105EX9 Membrane EGX53_12130 ENOG4108W1V Lipoprotein EGX53_12135 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) EGX53_12145 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A EGX53_12160 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase EGX53_12170 ENOG4105DQF Hydrolase EGX53_12175 ENOG4108EUD Lysophospholipase EGX53_12185 ENOG4105CCF Lysine exporter protein (Lyse ygga) EGX53_12190 ENOG4105C9U ATP-dependent DNA helicase RecQ EGX53_12195 ENOG4105HDD phospholipase EGX53_12200 ENOG4108VUY thioesterase Superfamily protein EGX53_12205 ENOG4105FR1 rard protein EGX53_12210 ENOG4107QUT magnesium and cobalt transport protein CorA EGX53_12220 ENOG4105EQN UPF0261 protein EGX53_12230 ENOG4105C4R Atp-dependent dna helicase EGX53_12235 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant EGX53_12240 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EGX53_12245 ENOG4105CT0 Protein of unknown function, DUF484 EGX53_12255 ENOG4105S7Z (LipO)protein EGX53_12265 ENOG4107T0K Adenylate cyclase EGX53_12280 ENOG41076E6 Uroporphyrinogen-III Synthase EGX53_12285 ENOG4105ECF c-methyltransferase EGX53_12290 ENOG410601J HemY protein EGX53_12320 ENOG4105C85 amino acid EGX53_12340 ENOG4105EGZ biosynthesis protein EGX53_12345 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase EGX53_12350 ENOG4108WJ1 acetyltransferase EGX53_12355 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) EGX53_12360 ENOG4105C1B dTDP-glucose 4-6-dehydratase EGX53_12365 ENOG4108IJ1 Dehydrogenase EGX53_12370 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase EGX53_12375 ENOG4105SFE lipopolysaccharide biosynthesis protein EGX53_12380 ENOG4105ESV Glycosyl transferase, family 4 EGX53_12390 ENOG4105K63 Thioredoxin EGX53_12405 ENOG4105C4R Atp-dependent dna helicase EGX53_12415 ENOG4105KQ5 peptidylprolyl cis-trans isomerase EGX53_12435 ENOG4105GQR Chaperone EGX53_12440 ENOG4105CW0 outer membrane usher protein EGX53_12450 ENOG4108VEV chaperone EGX53_12490 ENOG4105EMY transcriptional regulator EGX53_12510 ENOG4105C7B Threonine dehydratase EGX53_12520 ENOG4105CM2 brancheD-chain amino acid aminotransferase EGX53_12525 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit EGX53_12545 ENOG4105C0P Mg chelatase subunit ChlI EGX53_12550 ENOG4108WFC UPF0438 protein yifE EGX53_12560 ENOG41062B0 ABC transporter, permease EGX53_12565 ENOG4107R9N ABC transporter EGX53_12570 ENOG4105C2J ABC transporter EGX53_12575 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator EGX53_12635 ENOG4108Y73 Membrane EGX53_12650 ENOG4105C5Q Transcriptional regulator EGX53_12655 ENOG4105EHV domain protein EGX53_12660 ENOG4107QN2 dihydrolipoyl dehydrogenase EGX53_12665 ENOG4105YHG TonB family EGX53_12670 ENOG4107QZV Type I secretion membrane fusion protein EGX53_12685 ENOG4105X58 receptor EGX53_12725 ENOG4105SYT Methylenetetrahydrofolate reductase EGX53_12730 ENOG4105CFH Aspartokinase EGX53_12735 ENOG4105C28 cystathionine EGX53_12740 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) EGX53_12745 ENOG4108Z12 YiaAB two helix domain-containing protein EGX53_12755 ENOG4105C25 Primosomal protein n' EGX53_12765 ENOG4105ETE Transcriptional regulator (LacI family EGX53_12770 ENOG41063M6 Cell Division Protein EGX53_12785 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase EGX53_12810 ENOG4108MBX Secretion Protein EGX53_12815 ENOG4108JJA ABC, transporter EGX53_12840 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) EGX53_12845 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) EGX53_12850 ENOG4105CBT Fructose-1,6-bisphosphatase EGX53_12855 ENOG4105DP0 ferredoxin-NADP reductase EGX53_12860 ENOG4108VTS Membrane EGX53_12865 ENOG4105EBK exported protein EGX53_12875 ENOG4107F9Y LysR family transcriptional regulator EGX53_12885 ENOG4105JSC dimethylmenaquinone methyltransferase EGX53_12890 ENOG4107QPK )-transporter EGX53_12900 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein EGX53_12930 ENOG4105FMW periplasmic EGX53_12935 ENOG4105E3W Two component transcriptional regulator (Winged helix family EGX53_12940 ENOG4105E0F Histidine kinase EGX53_12945 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) EGX53_12950 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) EGX53_12955 ENOG4105D7W serine acetyltransferase EGX53_12975 ENOG4105VW4 glutaredoxin 3 EGX53_12980 ENOG4107YZP Rhodanese domain protein EGX53_12990 ENOG41063SB peptidase EGX53_12995 ENOG4105PXI polysaccharide deacetylase EGX53_13005 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) EGX53_13015 ENOG4105XA0 heptosyltransferase ii EGX53_13020 ENOG4105D16 lipopolysaccharide heptosyltransferase i EGX53_13025 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase EGX53_13045 ENOG4105W0E 50S ribosomal protein L33 EGX53_13065 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase EGX53_13090 ENOG4105DSJ YicC domain protein EGX53_13145 ENOG4105EN6 Membrane EGX53_13150 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) EGX53_13160 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) EGX53_13165 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) EGX53_13170 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase EGX53_13175 ENOG4105CB5 ATP-dependent DNA helicase recG EGX53_13185 ENOG4105D6U Sodium Glutamate Symporter EGX53_13190 ENOG4105C2W permease EGX53_13195 ENOG4105JV1 AsmA family EGX53_13200 ENOG4105SUU thioesterase domain EGX53_13215 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 EGX53_13225 ENOG4105C5F glutamine synthetase EGX53_13235 ENOG4105CUX Signal transduction histidine kinase EGX53_13240 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EGX53_13245 ENOG4105D4P Coproporphyrinogen iii oxidase EGX53_13270 ENOG4105C2M dna polymerase I EGX53_13275 ENOG4108Z33 Thiol disulfide Interchange Protein EGX53_13280 ENOG4105E27 serine threonine protein kinase EGX53_13285 ENOG4105PC1 Conserved Protein EGX53_13295 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b EGX53_13335 ENOG4107EJG GntR family transcriptional regulator EGX53_13340 ENOG4105C0R drug resistance transporter emrb qaca subfamily EGX53_13350 ENOG4108RVA ribokinase EGX53_13380 ENOG4108VVK transcriptional Regulator, AsnC EGX53_13385 ENOG4105QTB Flavodoxin EGX53_13405 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation EGX53_13415 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) EGX53_13460 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) EGX53_13465 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) EGX53_13470 ENOG4105C8U phosphate abc transporter EGX53_13475 ENOG4105E2Z phosphate ABC transporter (Permease EGX53_13495 ENOG4106PMH Extracellular solute-binding protein family 3 EGX53_13500 ENOG4105EAD ABC transporter EGX53_13505 ENOG4105DRP amino acid AbC transporter EGX53_13510 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 EGX53_13520 ENOG4105C7N Xanthine uracil vitamin C permease EGX53_13550 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins EGX53_13565 ENOG4105VG0 50S ribosomal protein l34 EGX53_13585 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) EGX53_13590 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) EGX53_13595 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EGX53_13600 ENOG410667J hydrolase EGX53_13615 ENOG4105C7B Threonine dehydratase EGX53_13620 ENOG4105D99 atp gtp-binding protein EGX53_13625 ENOG4105R2A (LipO)protein EGX53_13645 ENOG4105JKW Valine--pyruvate aminotransferase EGX53_13665 ENOG4107T9C Alpha amylase catalytic region EGX53_13685 ENOG4108ZG0 Ompa motb domain protein EGX53_13695 ENOG4108R3E Dna-3-methyladenine glycosylase i EGX53_13720 ENOG4106JH6 (LipO)protein EGX53_13725 ENOG4105CTS PTS system mannitol-specific EGX53_13735 ENOG4105E61 Mannitol repressor protein EGX53_13740 ENOG4108YYI Protein of unknown function (DUF2810) EGX53_13755 ENOG4105C8Q Methyl-accepting chemotaxis EGX53_13760 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) EGX53_13770 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) EGX53_13775 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) EGX53_13780 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein EGX53_13785 ENOG4108MG3 formate dehydrogenase EGX53_13800 ENOG4105EM7 Selenocysteine-specific translation elongation factor EGX53_13845 ENOG4105MEV Acyl-transferase EGX53_13850 ENOG4106EAR Fimbrial protein EGX53_13860 ENOG4108TTM chaperone EGX53_13870 ENOG4105CMG Carbohydrate kinase EGX53_13880 ENOG4105DFW ABC transporter EGX53_13890 ENOG4107RNG ABC transporter EGX53_13895 ENOG4105T16 Transcriptional regulator (AraC family) EGX53_13900 ENOG4105DFP Integrase EGX53_13930 ENOG4108IPW abc transporter atp-binding protein EGX53_13935 ENOG4105CM4 permease protein EGX53_13980 ENOG4105C85 amino acid EGX53_13990 ENOG4105DIJ Phosphoethanolamine transferase EGX53_13995 ENOG4108KX4 response regulator EGX53_14000 ENOG4105BZU Histidine kinase EGX53_14005 ENOG4105CXY transporter EGX53_14020 ENOG4105D5K Hemolysin activator protein EGX53_14030 ENOG4105DEF Extracellular solute-binding protein, family 5 EGX53_14035 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EGX53_14040 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EGX53_14045 ENOG4105C3U ABC transporter EGX53_14050 ENOG4108JQ7 (ABC) transporter EGX53_14055 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) EGX53_14060 ENOG4105BZU Histidine kinase EGX53_14065 ENOG4108PU9 oligogalacturonate-specific porin EGX53_14090 ENOG4105CS0 peptidase EGX53_14095 ENOG4107SS6 2-dehydro-3-deoxygluconokinase EGX53_14100 ENOG4105VSH 4-oxalocrotonate tautomerase EGX53_14105 ENOG4105CMB EAL domain-containing protein EGX53_14110 ENOG41066T0 asmA family EGX53_14115 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) EGX53_14120 ENOG4107H3J ribonuclease EGX53_14145 ENOG4105BZW Glycerate kinase EGX53_14150 ENOG4107QQ0 gntp family EGX53_14160 ENOG4107VHA regulatoR EGX53_14165 ENOG4105DC8 reductase EGX53_14170 ENOG4105D6S protein involved in catabolism of external DNA EGX53_14175 ENOG4105DGW oligopeptidase A EGX53_14195 ENOG4108M6U Universal stress protein A EGX53_14205 ENOG4105CJ3 phosphate transporter EGX53_14210 ENOG4105CBX hi0933 family EGX53_14225 ENOG4105CNN ABC, transporter EGX53_14230 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator EGX53_14240 ENOG4105D2N Aldolase EGX53_14250 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EGX53_14265 ENOG4105C2I pirin domain protein EGX53_14270 ENOG4105DIQ Transcriptional regulator EGX53_14275 ENOG4105C6Z Gluconate EGX53_14280 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family EGX53_14300 ENOG41076UM multiple antibiotic resistance (MarC)-related protein EGX53_14305 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) EGX53_14330 ENOG4108HRK Histidine kinase EGX53_14355 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) EGX53_14360 ENOG4105C6V Glycerol-3-phosphate dehydrogenase EGX53_14390 ENOG4105E98 transcriptional regulator DeoR family EGX53_14410 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) EGX53_14415 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) EGX53_14425 ENOG4105MJ2 Competence protein EGX53_14435 ENOG4105RID UPF0379 protein yhcN EGX53_14450 ENOG4105XFK Ferrous iron transport protein A EGX53_14455 ENOG4105BZM domain protein EGX53_14460 ENOG4108RRZ Transcription elongation factor GreB EGX53_14465 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EGX53_14470 ENOG4105E0F Histidine kinase EGX53_14485 ENOG4105VEJ Heat shock protein EGX53_14490 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 EGX53_14495 ENOG4105DQY intracellular growth attenuator EGX53_14500 ENOG4107RK2 ADP-ribose diphosphatase NudE EGX53_14510 ENOG4105UZW Tail fiber assembly protein EGX53_14585 ENOG4105NVB glycoside hydrolase, family 19 EGX53_14600 ENOG4105ZIA Phage protein gp16 EGX53_14675 ENOG4105HVQ Regulatory factor of maltose metabolism EGX53_14685 ENOG4108JQC penicillin-binding protein 1A EGX53_14715 ENOG4105E4G Type IV pilus EGX53_14740 ENOG4105DJV ribulose-phosphate 3-epimerase EGX53_14745 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) EGX53_14750 ENOG4105C31 Tryptophanyl-tRNA synthetase EGX53_14760 ENOG4107V9H nitrite transporter EGX53_14765 ENOG4105WZK nitrite reductase NADPH small subunit EGX53_14770 ENOG4107QZF nitrite reductase NADPH large subunit EGX53_14775 ENOG4105DZC cytosine deaminase EGX53_14790 ENOG41060NJ transcriptional regulator EGX53_14795 ENOG4105F8D glycoside hydrolase family 4 EGX53_14800 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) EGX53_14805 ENOG4105D7A ATP-binding protein EGX53_14815 ENOG4105C8Y Acetylornithine aminotransferase EGX53_14820 ENOG410613R integral membrane protein, YccS YhfK family EGX53_14830 ENOG4108UKZ OsmC family EGX53_14835 ENOG4105GMB type VI secretion system effector, hcp1 family EGX53_14850 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) EGX53_14860 ENOG4105DNZ Alpha Beta Hydrolase EGX53_14870 ENOG4106FTQ Taurine ABC transporter, periplasmic EGX53_14880 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component EGX53_14885 ENOG4105E2B Taurine dioxygenase EGX53_14895 ENOG4105K64 Glycosyl transferase, family 2 EGX53_14900 ENOG4105C5H ABC transporter EGX53_14905 ENOG4108K2R Glutathione-regulated potassium-efflux system ancillary protein EGX53_14915 ENOG4105VKU nucleicacid-binding protein EGX53_14920 ENOG4108YZY peptidylprolyl cis-trans isomerase EGX53_14935 ENOG4108V1T peptidylprolyl cis-trans isomerase EGX53_14940 ENOG4105WWK YheO domain protein EGX53_14965 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) EGX53_14985 ENOG4108RS6 transposase EGX53_15030 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) EGX53_15040 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) EGX53_15045 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) EGX53_15055 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal EGX53_15100 ENOG4105VPB 50S ribosomal protein L30 EGX53_15110 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) EGX53_15115 ENOG41067V7 50S ribosomal protein L36 EGX53_15130 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) EGX53_15145 ENOG4105W1Y Transcriptional regulator EGX53_15150 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system EGX53_15160 ENOG4105C1A potassium transporter peripheral membrane EGX53_15180 ENOG4105C79 DNA protecting protein DprA EGX53_15190 ENOG4108WI1 Dna topoisomerase EGX53_15205 ENOG4108Z0R Transferase EGX53_15245 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase EGX53_15285 ENOG4105PM1 preprotein translocase subunit SecE EGX53_15290 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) EGX53_15330 ENOG4105D41 biosynthesis protein thiH EGX53_15345 ENOG4105D06 uba thif-type nad fad binding protein EGX53_15355 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) EGX53_15380 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) EGX53_15385 ENOG4105R2J Conserved Protein EGX53_15395 ENOG4108T8B Protein of unknown function (DUF1481) EGX53_15400 ENOG4105C12 Phosphoribosylglycinamide synthetase EGX53_15460 ENOG4107QP3 malate synthase g EGX53_15465 ENOG4108I9X Isocitrate lyase EGX53_15475 ENOG41069M3 Transcriptional regulator EGX53_15480 ENOG4105C3R Methionine synthase EGX53_15490 ENOG4105CFH Aspartokinase EGX53_15505 ENOG4105EG2 ABC transporter, permease EGX53_15510 ENOG4105D56 permease protein EGX53_15515 ENOG4107FKK extracellular solute-binding protein family 1 EGX53_15535 ENOG4107W52 maltose operon periplasmic protein EGX53_15545 ENOG4108WC9 type VI secretion system effector, hcp1 family EGX53_15595 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EGX53_15630 ENOG4105CS6 Rhs element vgr protein EGX53_15690 ENOG4105CS6 Rhs element vgr protein EGX53_15705 ENOG4107TYG Oxidoreductase domain-containing protein EGX53_15715 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) EGX53_15720 ENOG4108RVA ribokinase EGX53_15725 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) EGX53_15735 ENOG4105GVF (ABC) transporter EGX53_15745 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component EGX53_15765 ENOG4105C7N Xanthine uracil vitamin C permease EGX53_15775 ENOG4105EEQ Na H antiporter EGX53_15785 ENOG4105D1S lipid A biosynthesis EGX53_15795 ENOG4105C2J ABC transporter EGX53_15800 ENOG4105CNN ABC, transporter EGX53_15810 ENOG4105EF1 ribulokinase EGX53_15815 ENOG4105C2X Arabinose 5-phosphate isomerase EGX53_15820 ENOG4105CYM Glutathione S-transferase EGX53_15835 ENOG4105VEQ Cold shock protein EGX53_15840 ENOG4105VEQ Cold shock protein EGX53_15845 ENOG4105VEQ Cold shock protein EGX53_15855 ENOG4108XTF Outer Membrane Lipoprotein EGX53_15870 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase EGX53_15875 ENOG4105CSH Transporter EGX53_15900 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) EGX53_15905 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) EGX53_15915 ENOG4108IA2 Sodium pantothenate symporter EGX53_15920 ENOG4105RG0 Membrane EGX53_15925 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase EGX53_15930 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein EGX53_15950 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family EGX53_15955 ENOG41062P1 Diguanylate cyclase phosphodiesterase EGX53_15960 ENOG4105DFF Rod shape-determining protein mreb EGX53_15965 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) EGX53_15970 ENOG4105VQ7 Rod shape-determining protein MreD EGX53_15980 ENOG4105C03 ribonuclease EGX53_15985 ENOG4105QD6 exported protein EGX53_15995 ENOG4105D1U peptidase U62 modulator of DNA gyrase EGX53_16040 ENOG4105CR8 Transcriptional regulator EGX53_16070 ENOG4105UNR (Barnase) inhibitor EGX53_16080 ENOG4105CMS peptidase U62, modulator of DNA gyrase EGX53_16090 ENOG4108XVM Cytochrome b(562) EGX53_16095 ENOG4105NXH GreA GreB family elongation factor EGX53_16100 ENOG4105CG3 alpha amylase, catalytic region EGX53_16105 ENOG4105C5Y PTS System EGX53_16110 ENOG4105D4X repressor EGX53_16120 ENOG4105KME endoribonuclease L-psp EGX53_16140 ENOG41080Z8 PHOSPHOCARRIER protein EGX53_16155 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN EGX53_16160 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA EGX53_16165 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX53_16170 ENOG4108IUZ ABC transporter EGX53_16175 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA EGX53_16180 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) EGX53_16185 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase EGX53_16190 ENOG4105C2X Arabinose 5-phosphate isomerase EGX53_16195 ENOG4105FEU K -dependent Na -Ca exchanger EGX53_16200 ENOG4105DHJ ABC, transporter EGX53_16205 ENOG4105CY3 ABC transporter, permease EGX53_16210 ENOG4107PE3 Mammalian cell entry related domain protein EGX53_16215 ENOG4105E3I toluene tolerance EGX53_16220 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane EGX53_16225 ENOG4105VFK BolA family EGX53_16235 ENOG4105C0H protease EGX53_16240 ENOG4105C0H protease EGX53_16245 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III EGX53_16250 ENOG4105D6Z AFG1 family ATPase EGX53_16270 ENOG4107MKT Stringent starvation protein a EGX53_16275 ENOG4105KB2 stringent starvation protein b EGX53_16285 ENOG4105BZ8 glutamate synthase EGX53_16290 ENOG4105CBC glutamate synthase EGX53_16295 ENOG4105N5T Radical SAM Protein EGX53_16305 ENOG4105BZU Histidine kinase EGX53_16315 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain EGX53_16325 ENOG4105W4M Transport-associated protein EGX53_16345 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) EGX53_16355 ENOG4108CNN domain protein EGX53_16360 ENOG4105CWB LysR family transcriptional Regulator EGX53_16370 ENOG4108VBZ doxx family EGX53_16380 ENOG41090KG Inner membrane protein YqjE EGX53_16385 ENOG4105NE1 Conserved Protein EGX53_16405 ENOG4106W5V Membrane EGX53_16420 ENOG4105DPW Major facilitator superfamily MFS_1 EGX53_16430 ENOG4107QZW Altronate oxidoreductase EGX53_16435 ENOG4105CTX dehydratase EGX53_16440 ENOG4105P66 Membrane EGX53_16450 ENOG4105EE0 oxidoreductase EGX53_16455 ENOG4108VKG metal-dependent hydrolase EGX53_16470 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase EGX53_16475 ENOG4108YK4 Acid-resistance membrane protein EGX53_16510 ENOG4108M24 von Willebrand factor, type A EGX53_16515 ENOG4105D5K Hemolysin activator protein EGX53_16545 ENOG4105CKT filamentous hemagglutinin EGX53_16555 ENOG4105CKT filamentous hemagglutinin EGX53_16560 ENOG4105CKT filamentous hemagglutinin EGX53_16575 ENOG4105CKT filamentous hemagglutinin EGX53_16580 ENOG4105CKT filamentous hemagglutinin EGX53_16605 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 EGX53_16610 ENOG4107KJX Transcriptional regulator EGX53_16615 ENOG4108IJG ABC transporter substrate-binding protein EGX53_16625 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component EGX53_16635 ENOG4107QK4 glycoside hydrolase, family 3 domain protein EGX53_16645 ENOG4108MI0 Resistance protein EGX53_16650 ENOG4105J12 Multidrug resistance protein mdtN EGX53_16670 ENOG4105CHM Aminotransferase EGX53_16690 ENOG4105KME endoribonuclease L-psp EGX53_16720 ENOG4105MZU cell filamentation protein EGX53_16730 ENOG4105GMB type VI secretion system effector, hcp1 family EGX53_16765 ENOG4105XB7 anti-repressor protein EGX53_16865 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) EGX53_16870 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) EGX53_16875 ENOG4105VCC 30S ribosomal protein S21 EGX53_16890 ENOG4107ZVW dihydroneopterin aldolase EGX53_16905 ENOG4106MWK domain protein EGX53_16910 ENOG4105I7R Adenylate cyclase EGX53_16925 ENOG4105DVH amino acid EGX53_16935 ENOG4105W0Z cytoplasmic protein EGX53_16945 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b EGX53_16950 ENOG4106032 Glutathionylspermidine synthase EGX53_16965 ENOG4105DFG type I secretion outer membrane protein EGX53_16970 ENOG41087AY ADP-Ribose pyrophosphatase EGX53_16975 ENOG4108SX3 cytoplasmic protein EGX53_16980 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) EGX53_16985 ENOG4105IPS esterase EGX53_16990 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EGX53_16995 ENOG4105CR8 Transcriptional regulator EGX53_17000 ENOG4105NF4 modulator of drug activity EGX53_17010 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) EGX53_17015 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase EGX53_17025 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) EGX53_17040 ENOG4105CV8 reductase EGX53_17050 ENOG4108I6A alcohol dehydrogenase EGX53_17055 ENOG4105CF7 AraC family transcriptional regulator EGX53_17060 ENOG4108K81 inner membrane protein YghB EGX53_17065 ENOG4105C28 cystathionine EGX53_17070 ENOG4105CWK Biopolymer transport protein, ExbB EGX53_17075 ENOG4108ZZF transport protein (ExbD) EGX53_17160 ENOG4108M1A Chitin-binding protein EGX53_17165 ENOG4105E03 chitinase EGX53_17175 ENOG4106PG1 outer membrane usher protein EGX53_17180 ENOG4106P2F Pfam:Pili_assembly_C EGX53_17190 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein EGX53_17210 ENOG4105D00 flagellar biosynthetic protein flhB EGX53_17215 ENOG4105D19 Role in flagellar biosynthesis (By similarity) EGX53_17220 ENOG4105VS8 Flagellar biosynthetic protein fliq EGX53_17225 ENOG4105CN7 Flagellar biosynthetic protein FliP EGX53_17230 ENOG4105DD5 Flagellar motor switch protein EGX53_17240 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EGX53_17250 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) EGX53_17265 ENOG4108JIR Flagellum-specific ATP synthase EGX53_17285 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA EGX53_17290 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) EGX53_17295 ENOG4108ZC9 flagellar basal-body rod protein flgc EGX53_17300 ENOG4105W00 Flagellar hook capping protein EGX53_17370 ENOG4108XTF Outer Membrane Lipoprotein EGX53_17380 ENOG4105BZU Histidine kinase EGX53_17390 ENOG4105C1P efflux transporter, rnd family, mfp subunit EGX53_17450 ENOG4105CFC Transporter EGX53_17455 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) EGX53_17460 ENOG4107ZSV Receptor EGX53_17465 ENOG4105C0W non-ribosomal peptide synthetase EGX53_17470 ENOG4105C0W non-ribosomal peptide synthetase EGX53_17500 ENOG4105BZ1 (ABC) transporter EGX53_17520 ENOG4107EFN gluconate transport system permease 3 EGX53_17530 ENOG4105CS6 Rhs element vgr protein EGX53_17600 ENOG41062WK cellular response to acidity EGX53_17605 ENOG4105C8P )-transporter EGX53_17610 ENOG4105ETE Transcriptional regulator (LacI family EGX53_17620 ENOG4105CT4 transporter EGX53_17630 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) EGX53_17635 ENOG4105DUU IucA IucC family protein EGX53_17720 ENOG4105CDV Ompa motb domain protein EGX53_17735 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EGX53_17780 ENOG4105CXN decarboxylase EGX53_17785 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator EGX53_17790 ENOG4105C2J ABC transporter EGX53_17795 ENOG4105CNN ABC, transporter EGX53_17825 ENOG4105CEN a g-specific adenine glycosylase EGX53_17835 ENOG41090ED Protein with unknown function (DUF469) EGX53_17840 ENOG4105CSV Glutaminase EGX53_17845 ENOG4105K33 Periplasmic Protein EGX53_17850 ENOG4105EUK rtx toxin RtxA EGX53_17855 ENOG4105CSA Coproporphyrinogen iii oxidase EGX53_17860 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) EGX53_17870 ENOG4108VIA integral membrane protein EGX53_17875 ENOG4105II7 pyrroline-5-carboxylate reductase EGX53_17880 ENOG4105DFA alanine racemase domain protein EGX53_17885 ENOG4105CZX twitching motility protein EGX53_17895 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) EGX53_17910 ENOG4105D7Z glutathione synthase EGX53_17915 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) EGX53_17925 ENOG4105RWS endonuclease I EGX53_17940 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) EGX53_17950 ENOG4108RS6 transposase EGX53_17960 ENOG4108RS6 transposase EGX53_17965 ENOG4108K0D peptidase, M48 EGX53_17975 ENOG4105CV1 Transketolase (EC 2.2.1.1) EGX53_17990 ENOG4105D2N Aldolase EGX53_18000 ENOG4105D64 Mechanosensitive ion channel EGX53_18010 ENOG4105MPN Membrane EGX53_18020 ENOG4105E66 phosphoriboisomerase A EGX53_18025 ENOG4108JQ1 Dehydrogenase EGX53_18030 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase EGX53_18055 ENOG4107RAQ aminopeptidase EGX53_18060 ENOG4105D0A hydroxylase EGX53_18065 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family EGX53_18110 ENOG4108UT2 hemolysin iii EGX53_18125 ENOG4105Y75 tpr repeat protein EGX53_18135 ENOG4105E3W Two component transcriptional regulator (Winged helix family EGX53_18140 ENOG4105EB3 Histidine kinase EGX53_18145 ENOG4105CT7 inner membrane cred family protein EGX53_18150 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) EGX53_18155 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) EGX53_18160 ENOG4105T95 Thiol disulfide interChange protein EGX53_18165 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) EGX53_18185 ENOG4105DFP Integrase EGX53_18370 ENOG4105NTW Transcriptional regulator EGX53_18375 ENOG4108UY0 (LipO)protein EGX53_18385 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator EGX53_18390 ENOG4105CNN ABC, transporter EGX53_18405 ENOG4107FKK extracellular solute-binding protein family 1 EGX53_18415 ENOG4105EG2 ABC transporter, permease EGX53_18425 ENOG4105C4C beta-galactosidase EGX53_18430 ENOG4105CI1 PTS System EGX53_18440 ENOG4105ETE Transcriptional regulator (LacI family EGX53_18450 ENOG4105DPW Major facilitator superfamily MFS_1 EGX53_18455 ENOG4105ETE Transcriptional regulator (LacI family EGX53_18470 ENOG4105D2N Aldolase EGX53_18480 ENOG4105ENH Sulfatase EGX53_18485 ENOG4105C4X radical SAM domain protein EGX53_18495 ENOG4105CHR reductase EGX53_18500 ENOG4105CE4 GlcNAc 6-P deacetylase EGX53_18505 ENOG4108YTN IIa component EGX53_18510 ENOG4105F3R pts system mannose fructose sorbose family iid EGX53_18515 ENOG4105ETZ PTS System EGX53_18520 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB EGX53_18525 ENOG4105E70 isomerase EGX53_18530 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of EGX53_18535 ENOG4105E98 transcriptional regulator DeoR family EGX53_18540 ENOG4105CBG Sulfatase EGX53_18570 ENOG4107B2H carbonic anhydrase EGX53_18590 ENOG4107QHF type ii secretion system protein e EGX53_18600 ENOG4105D7Q type ii secretion system EGX53_18655 ENOG4105C8Q Methyl-accepting chemotaxis EGX53_18670 ENOG4105EJC lysr family transcriptional regulator EGX53_18675 ENOG4105F27 Major Facilitator EGX53_18680 ENOG4105RQF LysR family Transcriptional regulator EGX53_18685 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) EGX53_18690 ENOG41060NJ transcriptional regulator EGX53_18720 ENOG4105CPC Aldo Keto reductase EGX53_18745 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase EGX53_18785 ENOG4105DSY exodeoxyribonuclease V, gamma EGX53_18790 ENOG4107QXK peptidase EGX53_18795 ENOG4107QKA exodeoxyribonuclease V beta EGX53_18800 ENOG4107QYX exodeoxyribonuclease v alpha EGX53_18810 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase EGX53_18830 ENOG4105CA3 membrane-bound lytic murein transglycosylase EGX53_18835 ENOG4105CUZ uba thif-type nad fad binding protein EGX53_18840 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) EGX53_18845 ENOG4105C9B Cysteine desulfurase EGX53_18855 ENOG4105ETT transcriptional Regulator, LysR family EGX53_18860 ENOG4105M08 Membrane EGX53_18880 ENOG4105EWT decarboxylase family EGX53_18895 ENOG4105WP7 tRNA pseudouridine synthase C EGX53_18900 ENOG4105DR9 pseudouridine synthase EGX53_18905 ENOG4105QDK Flavodoxin EGX53_18925 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) EGX53_18960 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) EGX53_18965 ENOG4105KNE Phosphatidate cytidylyltransferase EGX53_18970 ENOG4105DZP Membrane-associated zinc metalloprotease EGX53_18980 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) EGX53_19000 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) EGX53_19010 ENOG4105C0B DNA polymerase III (alpha subunit) EGX53_19020 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase EGX53_19035 ENOG4105M1T rho-binding antiterminator EGX53_19045 ENOG4108VWS Yaeq family EGX53_19050 ENOG4108YZN class I peptide chain release factor EGX53_19055 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion EGX53_19065 ENOG4108R96 Methyltransferase, YaeB family EGX53_19070 ENOG4108R8X outer membrane lipoprotein EGX53_19075 ENOG4105D01 (LipO)protein EGX53_19080 ENOG4108UMI ABC transporter, permease EGX53_19090 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase EGX53_19125 ENOG4105CV8 reductase EGX53_19145 ENOG4105E9H Lytic Murein transglycosylase EGX53_19155 ENOG4105D1A Methyltransferase EGX53_19165 ENOG4108JDX DNA polymerase iii, epsilon subunit EGX53_19175 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease EGX53_19185 ENOG4105GIJ Glycine betaine EGX53_19190 ENOG4108HQS Glycine betaine EGX53_19195 ENOG4108IJ7 Glycine betaine EGX53_19200 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) EGX53_19225 ENOG4108WMJ Protein of unknown function (DUF2002) EGX53_19230 ENOG4108SAJ Protein of unknown function (DUF1198) EGX53_19240 ENOG4105VEQ Cold shock protein EGX53_19245 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein EGX53_19250 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component EGX53_19255 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component EGX53_19260 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) EGX53_19265 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) EGX53_19295 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) EGX53_19315 ENOG4105XXV Acid-resistance protein EGX53_19325 ENOG4107SVH Potassium channel protein EGX53_19330 ENOG41086WQ Protein CrcB homolog EGX53_19345 ENOG4105VZJ PTS System EGX53_19350 ENOG4105CK1 PTS System EGX53_19355 ENOG4105VCP PTS System EGX53_19360 ENOG4105EZV Transcriptional regulator EGX53_19390 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 EGX53_19405 ENOG4105EEX Two component transcriptional regulator (Winged helix family EGX53_19415 ENOG4105C08 Histidine kinase EGX53_19445 ENOG4105XIQ Protein of unknown function (DUF2517) EGX53_19455 ENOG4107SEY Conserved Protein EGX53_19460 ENOG4105CVP deoxyribo-dipyrimidine photolyase EGX53_19465 ENOG4107RF4 Phosphodiesterase EGX53_19470 ENOG4107QNR UPF0135 protein EGX53_19475 ENOG4105P4J Allophanate hydrolase, subunit 1 EGX53_19480 ENOG4107R7A Allophanate hydrolase subunit 2 EGX53_19525 ENOG4105C1J atp-dependent rna helicase EGX53_19535 ENOG4108IYU L-aspartate oxidase EGX53_19545 ENOG41069PW sigma-e factor negative regulatory protein EGX53_19550 ENOG4105VQK sigma E regulatory protein, MucB RseB EGX53_19555 ENOG4105WMJ Positive regulator of sigma E, RseC MucC EGX53_19570 ENOG4105C3F Signal peptidase i EGX53_19590 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) EGX53_19600 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding EGX53_19605 ENOG4106G6Q Transcriptional regulator EGX53_19615 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB EGX53_19620 ENOG4108Z6B deaminase EGX53_19650 ENOG4107WP9 Histidine kinase EGX53_19655 ENOG4108SKK alpha helix protein EGX53_19660 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family EGX53_19665 ENOG4105C4K Nad synthetase EGX53_19670 ENOG4108YZA Nitrogen regulatory protein pii EGX53_19675 ENOG4108M21 EGX53_19680 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) EGX53_19700 ENOG4105D8G Major Facilitator superfamily EGX53_19705 ENOG4108MN2 Stationary phase inducible protein CsiE EGX53_19710 ENOG41065CD Exported protein EGX53_19715 ENOG4105D7X high-affinity nickel-transporter EGX53_19735 ENOG4105C3J Cysteine desulfurase EGX53_19740 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins EGX53_19765 ENOG4108ZIT Ferredoxin, 2FE-2S EGX53_19770 ENOG4105WVQ Fe-S assembly protein IscX EGX53_19780 ENOG4105YYA enhanced serine sensitivity protein SseB EGX53_19840 ENOG4105N21 Membrane EGX53_19845 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EGX53_19860 ENOG4105VPD cellular component movement EGX53_19870 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) EGX53_19880 ENOG4108WC9 type VI secretion system effector, hcp1 family EGX53_19945 ENOG4105DWF phosphomethylpyrimidine kinase EGX53_19955 ENOG4108ZGU inhibitor of vertebrate lysozyme EGX53_19970 ENOG4105CFP Peptidase U32 EGX53_19975 ENOG4105KWI UPF0339 protein EGX53_19980 ENOG4105E3W Two component transcriptional regulator (Winged helix family EGX53_19985 ENOG4105EB3 Histidine kinase EGX53_20010 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EGX53_20020 ENOG4108JPW Aminotransferase EGX53_20030 ENOG4105F38 ABC transporter, permease EGX53_20035 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component EGX53_20040 ENOG4105R8A Heat shock protein EGX53_20045 ENOG4105CJW magnesium transporter EGX53_20055 ENOG4105C9X ppx gppa phosphatase EGX53_20060 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) EGX53_20065 ENOG4105C8U phosphate abc transporter EGX53_20070 ENOG4105E2Z phosphate ABC transporter (Permease EGX53_20085 ENOG4108MK9 spermidine N(1)-acetyltransferase EGX53_20090 ENOG4108V3E phosphoribosylglycinamide formyltransferase EGX53_20105 ENOG4105C2W permease EGX53_20115 ENOG4105K89 arsenate reductase EGX53_20120 ENOG4105ERG peptidase m48, ste24p EGX53_20125 ENOG4105C02 permease EGX53_20140 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen EGX53_20145 ENOG4105RH4 Glycine cleavage system transcriptional repressor EGX53_20155 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) EGX53_20165 ENOG4105CGZ zinc metallopeptidase EGX53_20195 ENOG4105KUZ arsenate reductase EGX53_20205 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC EGX53_20210 ENOG4107Z33 ABC transporter, permease EGX53_20215 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) EGX53_20225 ENOG4105ENH Sulfatase EGX53_20230 ENOG4105C4X radical SAM domain protein EGX53_20235 ENOG4105S2T inner membrane protein YbcI EGX53_20245 ENOG4105BZS acriflavin resistance protein EGX53_20255 ENOG4105WH1 Two component transcriptional regulator luxr family EGX53_20260 ENOG4108ZNS ferredoxin-type protein NapF EGX53_20265 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase EGX53_20275 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) EGX53_20280 ENOG4105CUW cytochrome C-TYPE protein EGX53_20290 ENOG4105C6K Malic enzyme EGX53_20325 ENOG4105H4F exported protein EGX53_20330 ENOG4105E7K (LipO)protein EGX53_20335 ENOG4105EZR dyp-type peroxidase family protein EGX53_20360 ENOG4108R66 Conserved Protein EGX53_20370 ENOG4105QEK Transcriptional regulator EGX53_20380 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein EGX53_20385 ENOG4108I5D sulfate abc transporter EGX53_20390 ENOG4105ECW sulfate abc transporter EGX53_20400 ENOG4105C6T cysteine synthase EGX53_20405 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway EGX53_20410 ENOG4105DPZ Two component transcriptional regulator (Winged helix family EGX53_20415 ENOG41062D9 Histidine kinase EGX53_20425 ENOG4105C87 Aminotransferase class I and II EGX53_20430 ENOG4107RAQ aminopeptidase EGX53_20440 ENOG4105E1V na solute symporter EGX53_20455 ENOG4105DJY efflux transporter, rnd family, mfp subunit EGX53_20460 ENOG4105E3W Two component transcriptional regulator (Winged helix family EGX53_20465 ENOG4105E0F Histidine kinase EGX53_20470 ENOG4105C5Y PTS System EGX53_20480 ENOG4105KZ7 phosphocarrier protein hpr EGX53_20485 ENOG4105C6T cysteine synthase EGX53_20490 ENOG4105EXN Sulfate transport protein CysZ EGX53_20505 ENOG4105VRT cytoplasmic protein EGX53_20575 ENOG4105D9N nucleoside EGX53_20590 ENOG4105CPC Aldo Keto reductase EGX53_20595 ENOG4105C5Q Transcriptional regulator EGX53_20610 ENOG41072TH Protein of unknown function (DUF1479) EGX53_20615 ENOG4105CHM Aminotransferase EGX53_20620 ENOG4108VKM cytochrome b561 EGX53_20630 ENOG4106B0W Curli production assembly transport component CsgG EGX53_20640 ENOG4107Y60 (LipO)protein EGX53_20650 ENOG4108NEM leader-binding protein dmsD EGX53_20665 ENOG4107KGK dmso reductase anchor subunit EGX53_20670 ENOG4105QAX Iron-sulfur EGX53_20675 ENOG4107QY8 reductase EGX53_20685 ENOG4108WC9 type VI secretion system effector, hcp1 family EGX53_20710 ENOG4105CVE Lytic murein transglycosylase EGX53_20760 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit EGX53_20770 ENOG4105GQR Chaperone EGX53_20775 ENOG4105CW0 outer membrane usher protein EGX53_20820 ENOG4105CS6 Rhs element vgr protein EGX53_20850 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA EGX53_20865 ENOG4108V0P LemA family EGX53_20885 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) EGX53_20890 ENOG41060IM Heme exporter protein EGX53_20895 ENOG4105X3C heme exporter protein EGX53_20905 ENOG4105DA4 cytochrome c-type biogenesis protein EGX53_20910 ENOG4107QX9 Thiol disulfide interChange protein EGX53_20915 ENOG4105KWW Biogenesis protein EGX53_20920 ENOG4105KWW Biogenesis protein EGX53_20925 ENOG410903C (LipO)protein EGX53_20930 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation EGX53_20935 ENOG4105KZW UPF0381 protein EGX53_20950 ENOG4108BY2 phosphohistidine phosphatase EGX53_20960 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) EGX53_20975 ENOG4105EJ9 Membrane EGX53_20980 ENOG4108BPE -transporting atpase EGX53_20985 ENOG4105MH2 YfcL protein EGX53_20995 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EGX53_21010 ENOG4106WZ1 flagella biosynthesis regulator EGX53_21015 ENOG410631K Membrane EGX53_21030 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) EGX53_21040 ENOG4105DQR SNARE associated Golgi EGX53_21050 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase EGX53_21055 ENOG4108S3P Sporulation domain protein EGX53_21060 ENOG4105E96 Colicin v production protein EGX53_21065 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase EGX53_21070 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase EGX53_21075 ENOG4105E89 ABC transporter EGX53_21080 ENOG4105DSP amino acid AbC transporter EGX53_21085 ENOG4106YG3 ABC transporter EGX53_21090 ENOG4108JEH abc transporter atp-binding protein EGX53_21095 ENOG4105ECP epimerase EGX53_21110 ENOG4105PTV Nudix Hydrolase EGX53_21115 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC EGX53_21130 ENOG4107P2S Transcriptional regulator EGX53_21135 ENOG4105C6K Malic enzyme EGX53_21155 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 EGX53_21160 ENOG4107QWE )-transporter EGX53_21175 ENOG4105CHM Aminotransferase EGX53_21180 ENOG4107NQ8 LysR family Transcriptional regulator EGX53_21190 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) EGX53_21200 ENOG4105GKE subunit e EGX53_21205 ENOG4107QIZ NADH dehydrogenase EGX53_21210 ENOG4108IEH NADH dehydrogenase subunit g EGX53_21225 ENOG4107UFS subunit j EGX53_21235 ENOG4105D65 subunit l EGX53_21240 ENOG4105C8S subunit m EGX53_21255 ENOG4108R66 Conserved Protein EGX53_21260 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family EGX53_21265 ENOG4105CHR reductase EGX53_21270 ENOG4105F32 YngK protein EGX53_21280 ENOG4105K2J Transcriptional regulator EGX53_21285 ENOG4105C5I Dehydrogenase EGX53_21300 ENOG4105C01 Dihydroxy-acid dehydratase EGX53_21315 ENOG4105TNS Conserved Protein EGX53_21330 ENOG4105E4F Isochorismate synthase EGX53_21345 ENOG4108IPT Naphthoate synthase EGX53_21355 ENOG4105CEY Amp-dependent synthetase and ligase EGX53_21360 ENOG4108MTB glycosyl transferase family EGX53_21370 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction EGX53_21385 ENOG4107SDU Methyl-accepting chemotaxis EGX53_21390 ENOG4105CDA abc transporter atp-binding protein EGX53_21395 ENOG4105E5Q amino acid AbC transporter EGX53_21400 ENOG4107R0W ABC transporter EGX53_21435 ENOG4108T1M outer membrane protein x EGX53_21455 ENOG4105CPQ Dehydrogenase EGX53_21460 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator EGX53_21465 ENOG4105C2J ABC transporter EGX53_21470 ENOG4105CNN ABC, transporter EGX53_21475 ENOG4105FKQ transcriptional regulator EGX53_21480 ENOG4105EJC lysr family transcriptional regulator EGX53_21485 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) EGX53_21495 ENOG4105C94 Transporter EGX53_21500 ENOG4105DVW rieske (2Fe-2S) EGX53_21505 ENOG4105E3J oxidoreductase EGX53_21510 ENOG4105D5K Hemolysin activator protein EGX53_21535 ENOG4105CKT filamentous hemagglutinin EGX53_21555 ENOG4105TIV Cryptic phage CTXphi transcriptional repressor RstR EGX53_21570 ENOG4108IJ9 (ABC) transporter EGX53_21580 ENOG4105ETE Transcriptional regulator (LacI family EGX53_21595 ENOG4105DRS transport system, permease EGX53_21600 ENOG4105HY2 Glycosidase related protein EGX53_21625 ENOG4105CUY Mechanosensitive ion channel EGX53_21630 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) EGX53_21635 ENOG4107IIZ CRISPR-associated helicase, Cas3 EGX53_21640 ENOG4105ENG CRISPR-associated protein, Csy1 family EGX53_21645 ENOG4105DZX CRISPR-associated protein, Csy2 family EGX53_21650 ENOG4105M6W Crispr-associated protein, Csy3 family EGX53_21655 ENOG4108Y1S CRISPR-associated protein, Csy4 family EGX53_21660 ENOG4105CPC Aldo Keto reductase EGX53_21670 ENOG4105C54 Major Facilitator superfamily EGX53_21680 ENOG4105ETT transcriptional Regulator, LysR family EGX53_21685 ENOG4105VJY transcriptional regulator EGX53_21690 ENOG4107YC3 synthase EGX53_21715 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) EGX53_21720 ENOG4105DJ9 glucan biosynthesis protein EGX53_21725 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) EGX53_21730 ENOG4105NAC (LipO)protein EGX53_21735 ENOG4105DUX Transporter EGX53_21740 ENOG4105D1S lipid A biosynthesis EGX53_21760 ENOG4105DSF transport protein EGX53_21780 ENOG4105PVA Biofilm formation regulatory protein BssS EGX53_21800 ENOG41067V3 Antibiotic biosynthesis monooxygenase EGX53_21810 ENOG4107QQB Ribonuclease E EGX53_21820 ENOG4105EI2 Pseudouridine synthase EGX53_21825 ENOG4108RS6 transposase EGX53_21835 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein EGX53_21840 ENOG4105VGS 50s ribosomal protein l32 EGX53_21855 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase EGX53_21860 ENOG4105CHR reductase EGX53_21870 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) EGX53_21875 ENOG4105YAZ 4-amino-4-deoxychorismate lyase EGX53_21880 ENOG4105HHA aminodeoxychorismate lyase EGX53_21890 ENOG4107QRG dna polymerase iii EGX53_21895 ENOG4105F8V Hydrolase, tatD family EGX53_21900 ENOG4105CI1 PTS System EGX53_21905 ENOG4105F9E Shikimate 5-dehydrogenase EGX53_21910 ENOG4105K59 histidine triad (HIT) protein EGX53_21915 ENOG41090DQ Lipoprotein EGX53_21940 ENOG4105CEP NADH dehydrogenase EGX53_21955 ENOG4107MBR 17 kDa surface antigen EGX53_21960 ENOG4108JA2 transcriptioN-repair coupling factor EGX53_21965 ENOG4105D60 lipoprotein releasing system transmembrane protein EGX53_21975 ENOG4105D60 lipoprotein releasing system transmembrane protein EGX53_21990 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) EGX53_22000 ENOG4105EZE Cupin 4 family protein EGX53_22010 ENOG4105XJC Two component transcriptional regulator (Winged helix family EGX53_22020 ENOG4107QTF adenylosuccinate lyase