locus-tag	class	description
EGX53_00005	COG0457	Tetratricopeptide repeat
EGX53_00030	COG4886	Leucine-rich repeat (LRR) protein
EGX53_00040	COG3328	transposase activity
EGX53_00095	COG1192	Involved in chromosome partitioning
EGX53_00100	COG1475	DNA binding
EGX53_00115	COG3609	addiction module antidote protein, CC2985 family
EGX53_00125	COG5599	Phosphatase
EGX53_00315	COG5599	Phosphatase
EGX53_00320	COG1317	bacterial-type flagellum organization
EGX53_00330	COG4669	(LipO)protein
EGX53_00380	COG2207	Transcriptional regulator
EGX53_00390	COG4792	protein secretion
EGX53_00395	COG4791	protein targeting
EGX53_00400	COG4794	Type iii secretion
EGX53_00405	COG4790	Type iii secretion
EGX53_00410	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGX53_00455	COG4789	Type iii secretion
EGX53_00490	COG1187	pseudouridine synthase activity
EGX53_00495	COG0538	isocitrate dehydrogenase activity
EGX53_00510	COG0840	transmembrane signaling receptor activity
EGX53_00515	COG0702	epimerase
EGX53_00520	COG1733	regulation of RNA biosynthetic process
EGX53_00540	COG1522	sequence-specific DNA binding
EGX53_00550	COG0604	alcohol dehydrogenase
EGX53_00550	COG3321	synthase
EGX53_00550	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_00560	COG1278	Cold shock
EGX53_00570	COG0840	transmembrane signaling receptor activity
EGX53_00575	COG1285	pathogenesis
EGX53_00600	COG1360	Flagellar Motor Protein
EGX53_00605	COG0643	Histidine kinase
EGX53_00605	COG2198	Histidine kinase
EGX53_00610	COG0835	chemotaxis
EGX53_00625	COG0840	transmembrane signaling receptor activity
EGX53_00635	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
EGX53_00645	COG0745	RESPONSE REGULATOR receiver
EGX53_00650	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
EGX53_00660	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX53_00675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGX53_00720	COG3121	Chaperone
EGX53_00740	COG3008	intermembrane lipid transfer
EGX53_00745	COG2995	paraquat-inducible protein a
EGX53_00750	COG1956	GAF domain-containing protein
EGX53_00760	COG0793	Belongs to the peptidase S41A family
EGX53_00775	COG3539	Fimbrial protein
EGX53_00780	COG3121	Chaperone
EGX53_00795	COG3121	Chaperone
EGX53_00800	COG2814	Major facilitator Superfamily
EGX53_00805	COG0823	Involved in the tonB-independent uptake of proteins
EGX53_00815	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX53_00825	COG1988	membrane-bound metal-dependent
EGX53_00830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGX53_00835	COG1653	transport
EGX53_00840	COG3842	ATPase activity
EGX53_00845	COG0395	ABC-type sugar transport system, permease component
EGX53_00850	COG1175	transmembrane transport
EGX53_00860	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_00870	COG1917	Cupin 2, conserved barrel domain protein
EGX53_00880	COG3328	transposase activity
EGX53_00890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX53_00910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX53_00915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX53_00920	COG1121	(ABC) transporter
EGX53_00925	COG0803	Belongs to the bacterial solute-binding protein 9 family
EGX53_00950	COG4249	Peptidase C14 caspase catalytic subunit p20
EGX53_00990	COG0776	regulation of translation
EGX53_01005	COG0386	Belongs to the glutathione peroxidase family
EGX53_01010	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
EGX53_01055	COG0791	NLP P60 protein
EGX53_01080	COG0574	Belongs to the PEP-utilizing enzyme family
EGX53_01080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX53_01090	COG0628	permease
EGX53_01095	COG0277	FAD linked oxidase domain protein
EGX53_01095	COG0247	lactate metabolic process
EGX53_01100	COG2050	protein possibly involved in aromatic compounds catabolism
EGX53_01110	COG0316	Belongs to the HesB IscA family
EGX53_01115	COG0719	Fe-S assembly protein
EGX53_01120	COG0396	ATPase activity
EGX53_01125	COG0719	Fe-S assembly protein
EGX53_01140	COG1388	LysM domain
EGX53_01140	COG1376	ErfK ybiS ycfS ynhG family protein
EGX53_01145	COG4238	major outer membrane lipoprotein
EGX53_01180	COG0307	riboflavin synthase, alpha
EGX53_01185	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
EGX53_01190	COG2814	Major facilitator Superfamily
EGX53_01195	COG0583	DNA-binding transcription factor activity
EGX53_01210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGX53_01215	COG0791	NLP P60 protein
EGX53_01225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGX53_01240	COG0346	lactoylglutathione lyase activity
EGX53_01250	COG1902	pentaerythritol trinitrate reductase activity
EGX53_01255	COG1309	transcriptional regulator
EGX53_01265	COG3133	Outer membrane lipoprotein
EGX53_01275	COG3895	Periplasmic Protein
EGX53_01295	COG0625	glutathione transferase activity
EGX53_01310	COG3104	oligopeptide transport
EGX53_01315	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX53_01315	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX53_01320	COG4172	Belongs to the ABC transporter superfamily
EGX53_01330	COG4171	peptide transport system, permease
EGX53_01335	COG4168	peptide transport system, permease
EGX53_01340	COG4166	transmembrane transport
EGX53_01350	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
EGX53_01355	COG1842	Phage shock protein A
EGX53_01365	COG1983	PspC domain protein
EGX53_01375	COG3106	COG3106 Predicted ATPase
EGX53_01400	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
EGX53_01405	COG4948	Mandelate Racemase Muconate Lactonizing
EGX53_01410	COG2866	Carboxypeptidase
EGX53_01415	COG4166	transmembrane transport
EGX53_01435	COG0657	acetylesterase activity
EGX53_01435	COG2755	lipolytic protein G-D-S-L family
EGX53_01445	COG0674	pyruvate-flavodoxin oxidoreductase activity
EGX53_01445	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
EGX53_01445	COG1013	pyruvate-flavodoxin oxidoreductase activity
EGX53_01445	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX53_01455	COG1285	pathogenesis
EGX53_01460	COG3042	response to heat
EGX53_01465	COG3187	Heat shock protein
EGX53_01470	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX53_01475	COG2911	Protein conserved in bacteria
EGX53_01485	COG3784	Protein of unknown function (DUF1318)
EGX53_01490	COG0246	Mannitol dehydrogenase
EGX53_01495	COG2390	Transcriptional regulator
EGX53_01505	COG1643	Atp-dependent helicase
EGX53_01520	COG3591	Belongs to the peptidase S1B family
EGX53_01535	COG3038	cytochrome b561
EGX53_01560	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
EGX53_01565	COG2205	protein histidine kinase activity
EGX53_01570	COG0745	RESPONSE REGULATOR receiver
EGX53_01580	COG0531	amino acid
EGX53_01595	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
EGX53_01600	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
EGX53_01605	COG0589	response to stress
EGX53_01610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGX53_01615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX53_01630	COG1011	Hydrolase
EGX53_01635	COG0440	acetolactate synthase activity
EGX53_01640	COG0028	Belongs to the TPP enzyme family
EGX53_01670	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGX53_01675	COG1116	anion transmembrane transporter activity
EGX53_01680	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX53_01685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGX53_01695	COG1129	ABC transporter
EGX53_01700	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_01705	COG1879	ABC-type sugar transport system periplasmic component
EGX53_01715	COG1609	Transcriptional regulator
EGX53_01720	COG1757	Na H antiporter
EGX53_01725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGX53_01755	COG1012	belongs to the aldehyde dehydrogenase family
EGX53_01760	COG3284	Transcriptional regulator
EGX53_01765	COG4221	oxidoreductase activity
EGX53_01785	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGX53_01790	COG1940	carbohydrate kinase activity
EGX53_01795	COG0583	DNA-binding transcription factor activity
EGX53_01800	COG2814	Major facilitator Superfamily
EGX53_01810	COG0114	fumarate hydratase activity
EGX53_01820	COG5339	Protein conserved in bacteria
EGX53_01845	COG0385	Bile acid
EGX53_01850	COG0673	inositol 2-dehydrogenase activity
EGX53_01860	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_01870	COG1879	ABC-type sugar transport system periplasmic component
EGX53_01885	COG2274	protein secretion by the type I secretion system
EGX53_01895	COG2274	protein secretion by the type I secretion system
EGX53_01920	COG3708	Transcriptional regulator
EGX53_01920	COG2207	Transcriptional regulator
EGX53_01930	COG4659	FMN binding
EGX53_01940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX53_01945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX53_01950	COG2271	Major facilitator Superfamily
EGX53_01960	COG1966	Carbon starvation protein
EGX53_01965	COG2879	small protein
EGX53_01970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGX53_01990	COG0023	Translation Initiation Factor
EGX53_02005	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
EGX53_02010	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
EGX53_02015	COG0671	phosphoesterase, PA-phosphatase related
EGX53_02020	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX53_02025	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGX53_02035	COG0583	DNA-binding transcription factor activity
EGX53_02040	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX53_02055	COG0616	signal peptide processing
EGX53_02060	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_02070	COG1187	pseudouridine synthase activity
EGX53_02075	COG0009	L-threonylcarbamoyladenylate synthase
EGX53_02100	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX53_02110	COG0134	indole-3-glycerol-phosphate synthase activity
EGX53_02110	COG0135	phosphoribosylanthranilate isomerase activity
EGX53_02130	COG3047	cAMP biosynthetic process
EGX53_02160	COG1607	acyl-coa hydrolase
EGX53_02165	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
EGX53_02170	COG2350	Protein conserved in bacteria
EGX53_02210	COG4608	Belongs to the ABC transporter superfamily
EGX53_02215	COG0444	Belongs to the ABC transporter superfamily
EGX53_02220	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX53_02225	COG0601	transmembrane transport
EGX53_02235	COG2095	MarC family integral membrane protein
EGX53_02245	COG1454	alcohol dehydrogenase
EGX53_02245	COG1012	belongs to the aldehyde dehydrogenase family
EGX53_02250	COG1435	thymidine kinase activity
EGX53_02260	COG1943	Transposase
EGX53_02270	COG0745	RESPONSE REGULATOR receiver
EGX53_02280	COG0788	formyltetrahydrofolate deformylase activity
EGX53_02305	COG0583	DNA-binding transcription factor activity
EGX53_02310	COG0708	Exodeoxyribonuclease III
EGX53_02315	COG0494	nUDIX hydrolase
EGX53_02325	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
EGX53_02335	COG0778	Nitroreductase
EGX53_02340	COG0616	signal peptide processing
EGX53_02345	COG0252	asparaginase activity
EGX53_02350	COG1335	isochorismatase
EGX53_02355	COG3139	Protein of unknown function (DUF1315)
EGX53_02375	COG3713	MltA-interacting MipA family protein
EGX53_02385	COG2766	serine protein kinase
EGX53_02400	COG0583	DNA-binding transcription factor activity
EGX53_02410	COG2814	Major facilitator Superfamily
EGX53_02420	COG2719	SpoVR family
EGX53_02455	COG1104	cysteine desulfurase activity
EGX53_02470	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGX53_02475	COG2951	lytic endotransglycosylase activity
EGX53_02495	COG2894	cell division
EGX53_02500	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
EGX53_02505	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
EGX53_02510	COG0318	PFAM AMP-dependent synthetase and ligase
EGX53_02520	COG3065	identical protein binding
EGX53_02530	COG1199	ATP-dependent helicase activity
EGX53_02535	COG0251	oxidation-reduction process
EGX53_02550	COG0800	Aldolase
EGX53_02560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
EGX53_02565	COG1737	Transcriptional regulator
EGX53_02570	COG0469	pyruvate kinase activity
EGX53_02580	COG1560	Kdo2-lipid A biosynthetic process
EGX53_02585	COG0739	heme binding
EGX53_02590	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
EGX53_02600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX53_02630	COG0494	nUDIX hydrolase
EGX53_02640	COG1801	Protein of unknown function DUF72
EGX53_02645	COG3788	relative of glutathione S-transferase, MAPEG superfamily
EGX53_02665	COG3102	Protein conserved in bacteria
EGX53_02685	COG0728	peptidoglycan biosynthetic process
EGX53_02690	COG0673	inositol 2-dehydrogenase activity
EGX53_02700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX53_02715	COG3381	protein complex oligomerization
EGX53_02730	COG1940	carbohydrate kinase activity
EGX53_02735	COG0584	glycerophosphoryl diester phosphodiesterase
EGX53_02745	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX53_02750	COG3833	ABC-type maltose transport systems, permease component
EGX53_02775	COG0659	secondary active sulfate transmembrane transporter activity
EGX53_02785	COG2912	Transglutaminase-like superfamily
EGX53_02790	COG3094	Invasion gene expression up-regulator, SirB
EGX53_02795	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX53_02820	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGX53_02835	COG0012	GTP binding
EGX53_02865	COG5002	protein histidine kinase activity
EGX53_02905	COG0500	methyltransferase
EGX53_02970	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX53_02975	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
EGX53_02990	COG0402	S-adenosylhomocysteine deaminase activity
EGX53_03040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX53_03050	COG3850	Histidine kinase
EGX53_03055	COG0387	Pfam Sodium calcium exchanger
EGX53_03060	COG1943	Transposase
EGX53_03065	COG1702	phosphate starvation-inducible protein PhoH
EGX53_03080	COG3658	cytochrome
EGX53_03085	COG1215	transferase activity, transferring glycosyl groups
EGX53_03090	COG1649	PFAM Uncharacterised BCR, COG1649
EGX53_03090	COG0726	polysaccharide deacetylase
EGX53_03095	COG0457	Tetratricopeptide repeat
EGX53_03100	COG0006	proline dipeptidase activity
EGX53_03120	COG0577	efflux transmembrane transporter activity
EGX53_03120	COG1136	(ABC) transporter
EGX53_03130	COG1136	(ABC) transporter
EGX53_03130	COG0577	efflux transmembrane transporter activity
EGX53_03145	COG0672	)-iron permease
EGX53_03155	COG2066	Belongs to the glutaminase family
EGX53_03165	COG1349	DNA-binding transcription factor activity
EGX53_03180	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EGX53_03220	COG2030	dehydratase
EGX53_03225	COG0427	acetyl-CoA hydrolase
EGX53_03235	COG2205	protein histidine kinase activity
EGX53_03235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX53_03250	COG3188	usher protein
EGX53_03260	COG3121	Chaperone
EGX53_03280	COG0395	ABC-type sugar transport system, permease component
EGX53_03285	COG1175	transmembrane transport
EGX53_03295	COG0673	inositol 2-dehydrogenase activity
EGX53_03415	COG4974	Belongs to the 'phage' integrase family
EGX53_03470	COG2176	DNA-directed DNA polymerase activity
EGX53_03470	COG5002	protein histidine kinase activity
EGX53_03500	COG4695	Portal protein
EGX53_03675	COG2197	response regulator
EGX53_03685	COG3136	membrane protein required for alginate biosynthesis
EGX53_03710	COG1113	amino acid transport
EGX53_03750	COG0506	proline dehydrogenase activity
EGX53_03750	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGX53_03750	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGX53_03790	COG1191	sigma factor activity
EGX53_03825	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
EGX53_03830	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
EGX53_03850	COG1677	Flagellar hook-basal body complex protein FliE
EGX53_03860	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
EGX53_03870	COG1157	protein secretion by the type III secretion system
EGX53_03875	COG2882	bacterial-type flagellum organization
EGX53_03885	COG1580	Controls the rotational direction of flagella during chemotaxis
EGX53_03910	COG1987	bacterial-type flagellum assembly
EGX53_03925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX53_03930	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_03935	COG1129	ABC transporter
EGX53_03945	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_03950	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_03950	COG3347	Dehydrogenase
EGX53_03955	COG2390	Transcriptional regulator
EGX53_03965	COG1256	bacterial-type flagellum assembly
EGX53_03985	COG4786	Flagellar basal body rod
EGX53_03995	COG1749	Flagellar hook protein flgE
EGX53_04000	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EGX53_04005	COG1558	bacterial-type flagellum-dependent cell motility
EGX53_04010	COG1815	bacterial-type flagellum-dependent cell motility
EGX53_04020	COG2747	anti-sigma28 factor FlgM
EGX53_04025	COG3418	PFAM FlgN family protein
EGX53_04040	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX53_04045	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX53_04080	COG2372	response to copper ion
EGX53_04085	COG1528	Iron-storage protein
EGX53_04100	COG1770	oligopeptidase
EGX53_04115	COG3141	response to X-ray
EGX53_04120	COG0513	Belongs to the DEAD box helicase family
EGX53_04145	COG1760	l-serine dehydratase
EGX53_04150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGX53_04155	COG2368	4-hydroxyphenylacetate
EGX53_04170	COG3971	2-oxopent-4-enoate hydratase activity
EGX53_04180	COG3384	dioxygenase
EGX53_04185	COG1012	belongs to the aldehyde dehydrogenase family
EGX53_04200	COG1846	Transcriptional regulator
EGX53_04210	COG1253	flavin adenine dinucleotide binding
EGX53_04215	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX53_04215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX53_04220	COG3715	PTS system
EGX53_04225	COG3716	PTS system mannose fructose sorbose family IID component
EGX53_04245	COG3447	MASE1 domain protein
EGX53_04245	COG5002	protein histidine kinase activity
EGX53_04245	COG5001	Diguanylate cyclase
EGX53_04255	COG2226	methyltransferase
EGX53_04265	COG1278	Cold shock
EGX53_04285	COG1113	amino acid transport
EGX53_04325	COG2207	Transcriptional regulator
EGX53_04335	COG1132	(ABC) transporter
EGX53_04370	COG2223	nitrite transmembrane transporter activity
EGX53_04390	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
EGX53_04415	COG3122	Protein conserved in bacteria
EGX53_04435	COG0534	Mate efflux family protein
EGX53_04455	COG4948	Mandelate Racemase Muconate Lactonizing
EGX53_04465	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_04475	COG3011	Protein conserved in bacteria
EGX53_04480	COG2271	Major facilitator Superfamily
EGX53_04485	COG1388	LysM domain
EGX53_04485	COG1470	cell adhesion involved in biofilm formation
EGX53_04500	COG2925	Exonuclease
EGX53_04515	COG0531	amino acid
EGX53_04525	COG0371	Dehydrogenase
EGX53_04530	COG1129	ABC transporter
EGX53_04535	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_04540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX53_04555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGX53_04570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGX53_04585	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGX53_04585	COG0140	phosphoribosyl-ATP diphosphatase activity
EGX53_04595	COG1943	Transposase
EGX53_04605	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX53_04610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX53_04615	COG4264	IucA IucC family
EGX53_04625	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX53_04630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX53_04635	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX53_04640	COG1120	ATPase activity
EGX53_04655	COG3486	L-lysine 6-monooxygenase (NADPH) activity
EGX53_04660	COG0076	glutamate decarboxylase activity
EGX53_04665	COG4114	ferric iron reductase
EGX53_04670	COG1253	flavin adenine dinucleotide binding
EGX53_04675	COG2982	Protein involved in outer membrane biogenesis
EGX53_04690	COG0489	protein tyrosine kinase activity
EGX53_04715	COG2814	Major facilitator Superfamily
EGX53_04725	COG1346	cytolysis
EGX53_04740	COG2949	membrane
EGX53_04745	COG4211	Belongs to the binding-protein-dependent transport system permease family
EGX53_04760	COG2311	Membrane
EGX53_04770	COG0477	Major facilitator Superfamily
EGX53_04775	COG0583	DNA-binding transcription factor activity
EGX53_04805	COG1136	(ABC) transporter
EGX53_04815	COG0303	'Molybdopterin
EGX53_04830	COG0488	(ABC) transporter
EGX53_04930	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGX53_04935	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EGX53_04945	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_04950	COG1024	Enoyl-CoA hydratase
EGX53_04960	COG3425	synthase
EGX53_04965	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_04970	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX53_04975	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
EGX53_04985	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_05010	COG2920	part of a sulfur-relay system
EGX53_05030	COG1832	CoA-binding protein
EGX53_05035	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EGX53_05045	COG0210	DNA helicase
EGX53_05050	COG3304	Inner membrane component domain
EGX53_05055	COG1289	transmembrane transporter activity
EGX53_05060	COG3070	regulator of competence-specific genes
EGX53_05070	COG2885	chlorophyll binding
EGX53_05070	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EGX53_05075	COG1943	Transposase
EGX53_05085	COG1067	ATP-dependent peptidase activity
EGX53_05100	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX53_05105	COG3130	regulation of translation
EGX53_05115	COG3009	Protein conserved in bacteria
EGX53_05120	COG3008	intermembrane lipid transfer
EGX53_05120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGX53_05125	COG2995	paraquat-inducible protein a
EGX53_05130	COG0488	(ABC) transporter
EGX53_05140	COG0633	Ferredoxin
EGX53_05140	COG3217	Mosc domain protein beta barrel domain protein
EGX53_05155	COG0308	aminopeptidase N
EGX53_05175	COG1448	Aminotransferase
EGX53_05180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX53_05185	COG3108	Peptidase M15
EGX53_05190	COG2989	Protein conserved in bacteria
EGX53_05200	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
EGX53_05205	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
EGX53_05210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EGX53_05220	COG3173	Aminoglycoside phosphotransferase
EGX53_05235	COG2835	tetraacyldisaccharide 4'-kinase activity
EGX53_05240	COG1278	Cold shock
EGX53_05250	COG5383	Protein conserved in bacteria
EGX53_05280	COG0539	negative regulation of cytoplasmic translation
EGX53_05310	COG0252	asparaginase activity
EGX53_05315	COG1944	ATP diphosphatase activity
EGX53_05320	COG2116	formate transmembrane transporter activity
EGX53_05325	COG1882	Formate acetyltransferase
EGX53_05335	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
EGX53_05350	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGX53_05360	COG3107	peptidoglycan biosynthetic process
EGX53_05360	COG1674	ftsk spoiiie
EGX53_05370	COG0492	ferredoxin-NADP+ reductase activity
EGX53_05380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
EGX53_05390	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
EGX53_05395	COG0542	response to heat
EGX53_05410	COG1278	Cold shock
EGX53_05420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX53_05425	COG2990	Protein conserved in bacteria
EGX53_05430	COG3593	DNA synthesis involved in DNA repair
EGX53_05435	COG2431	L-lysine efflux transmembrane transporter activity
EGX53_05445	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX53_05450	COG0028	Belongs to the TPP enzyme family
EGX53_05455	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
EGX53_05460	COG0702	epimerase
EGX53_05465	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX53_05475	COG1605	Chorismate mutase
EGX53_05480	COG1126	abc transporter atp-binding protein
EGX53_05485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX53_05490	COG4215	(ABC) transporter
EGX53_05495	COG4160	amino acid transport
EGX53_05515	COG1120	ATPase activity
EGX53_05520	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX53_05540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX53_05555	COG1177	transmembrane transport
EGX53_05560	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX53_05565	COG3842	ATPase activity
EGX53_05570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
EGX53_05590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX53_05595	COG2985	domain, Protein
EGX53_05595	COG0569	domain protein
EGX53_05610	COG0671	phosphoesterase, PA-phosphatase related
EGX53_05615	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGX53_05620	COG1349	DNA-binding transcription factor activity
EGX53_05625	COG0814	amino acid
EGX53_05630	COG1686	Belongs to the peptidase S11 family
EGX53_05635	COG2011	ABC-type metal ion transport system permease component
EGX53_05660	COG0625	glutathione transferase activity
EGX53_05665	COG4771	TonB-dependent receptor
EGX53_05675	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX53_05685	COG0833	amino acid
EGX53_05690	COG0583	DNA-binding transcription factor activity
EGX53_05695	COG2855	membrane
EGX53_05705	COG3188	usher protein
EGX53_05710	COG3121	Chaperone
EGX53_05725	COG3710	Transcriptional regulator
EGX53_05730	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX53_05730	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX53_05730	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EGX53_05735	COG1105	Belongs to the carbohydrate kinase PfkB family
EGX53_05745	COG0494	nUDIX hydrolase
EGX53_05750	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_05755	COG1129	ABC transporter
EGX53_05765	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGX53_05790	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_05810	COG1312	Catalyzes the dehydration of D-mannonate
EGX53_05815	COG0246	Mannitol dehydrogenase
EGX53_05820	COG2186	Transcriptional regulator
EGX53_05830	COG0523	cobalamin synthesis protein
EGX53_05835	COG0671	phosphoesterase, PA-phosphatase related
EGX53_05840	COG0791	NLP P60 protein
EGX53_05845	COG2200	EAL domain
EGX53_05850	COG4166	transmembrane transport
EGX53_05855	COG4174	ABC transporter (Permease)
EGX53_05860	COG4239	(ABC) transporter, permease
EGX53_05865	COG4172	Belongs to the ABC transporter superfamily
EGX53_05875	COG2814	Major facilitator Superfamily
EGX53_05880	COG1187	pseudouridine synthase activity
EGX53_05885	COG1061	Type III restriction enzyme res subunit
EGX53_05900	COG3082	Protein of unknown function (DUF1414)
EGX53_05905	COG3083	sulfuric ester hydrolase activity
EGX53_05950	COG2723	6-phospho-beta-galactosidase activity
EGX53_05955	COG1737	Transcriptional regulator
EGX53_05975	COG3299	homolog of phage Mu protein gp47
EGX53_06015	COG4386	tail sheath protein
EGX53_06035	COG3622	Belongs to the hyi family
EGX53_06040	COG1349	DNA-binding transcription factor activity
EGX53_06050	COG3395	kinase activity
EGX53_06095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGX53_06120	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
EGX53_06125	COG2223	nitrite transmembrane transporter activity
EGX53_06130	COG2198	Histidine kinase
EGX53_06130	COG0642	Histidine kinase
EGX53_06140	COG2205	protein histidine kinase activity
EGX53_06140	COG0784	Response regulator, receiver
EGX53_06165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX53_06185	COG0814	amino acid
EGX53_06210	COG0697	spore germination
EGX53_06220	COG1982	Orn Lys Arg decarboxylase major
EGX53_06225	COG0531	amino acid
EGX53_06230	COG1174	glycine betaine transport
EGX53_06235	COG1125	glycine betaine transport
EGX53_06240	COG1174	glycine betaine transport
EGX53_06245	COG1732	Glycine betaine
EGX53_06250	COG2897	thiosulfate sulfurtransferase activity
EGX53_06265	COG0410	ABC transporter
EGX53_06270	COG1122	ATPase activity
EGX53_06290	COG4807	Protein conserved in bacteria
EGX53_06305	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
EGX53_06315	COG2261	transglycosylase associated protein
EGX53_06325	COG1403	HNH endonuclease
EGX53_06335	COG0277	FAD linked oxidase domain protein
EGX53_06340	COG1686	Belongs to the peptidase S11 family
EGX53_06350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX53_06360	COG1943	Transposase
EGX53_06405	COG0513	Belongs to the DEAD box helicase family
EGX53_06410	COG1309	transcriptional regulator
EGX53_06420	COG1131	(ABC) transporter
EGX53_06425	COG0842	Transport permease protein
EGX53_06430	COG0842	Transport permease protein
EGX53_06450	COG1902	pentaerythritol trinitrate reductase activity
EGX53_06470	COG2211	Major facilitator Superfamily
EGX53_06475	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
EGX53_06485	COG0583	DNA-binding transcription factor activity
EGX53_06490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX53_06510	COG0670	Belongs to the BI1 family
EGX53_06515	COG0314	molybdopterin synthase activity
EGX53_06520	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
EGX53_06530	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGX53_06535	COG0391	Required for morphogenesis under gluconeogenic growth conditions
EGX53_06540	COG4628	conserved protein (DUF2132)
EGX53_06555	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
EGX53_06560	COG2226	methyltransferase
EGX53_06585	COG0561	phosphatase activity
EGX53_06595	COG4149	molybdate abc transporter
EGX53_06600	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGX53_06610	COG3585	molybdate ion transport
EGX53_06610	COG2005	Transcriptional regulator
EGX53_06615	COG1119	ATPase activity
EGX53_06625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGX53_06630	COG1085	galactose-1-phosphate uridylyltransferase
EGX53_06640	COG2017	converts alpha-aldose to the beta-anomer
EGX53_06655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGX53_06660	COG1230	cation diffusion facilitator family transporter
EGX53_06705	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
EGX53_06710	COG2885	chlorophyll binding
EGX53_06720	COG3064	Membrane
EGX53_06720	COG3064	Membrane
EGX53_06725	COG0848	biopolymer transport protein
EGX53_06730	COG0811	peptide transport
EGX53_06735	COG0824	Thioesterase
EGX53_06740	COG3790	cyd operon protein YbgE
EGX53_06745	COG4890	Cyd operon protein YbgT
EGX53_06750	COG1294	oxidase, subunit
EGX53_06755	COG1271	oxidase subunit
EGX53_06760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
EGX53_06770	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX53_06775	COG0567	Dehydrogenase, E1 component
EGX53_06785	COG1053	succinate dehydrogenase
EGX53_06790	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGX53_06795	COG2009	succinate dehydrogenase
EGX53_06810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGX53_06815	COG0497	DNA recombination
EGX53_06820	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX53_06830	COG2867	negative regulation of translational initiation
EGX53_06845	COG0582	viral genome integration into host DNA
EGX53_06855	COG0582	viral genome integration into host DNA
EGX53_06865	COG0596	Alpha beta hydrolase
EGX53_06885	COG0735	belongs to the Fur family
EGX53_06905	COG1943	Transposase
EGX53_06915	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX53_06915	COG1263	PTS System
EGX53_06915	COG2190	(PTS) system
EGX53_06925	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
EGX53_06930	COG1940	carbohydrate kinase activity
EGX53_06930	COG1846	Transcriptional regulator
EGX53_06935	COG0647	UMP catabolic process
EGX53_06940	COG0367	asparagine synthase
EGX53_06980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX53_06990	COG1702	phosphate starvation-inducible protein PhoH
EGX53_07000	COG4535	Mg2 and Co2 transporter CorC
EGX53_07005	COG0815	Transfers the fatty acyl group on membrane lipoproteins
EGX53_07015	COG0765	amino acid transport
EGX53_07020	COG0765	amino acid transport
EGX53_07025	COG1126	abc transporter atp-binding protein
EGX53_07030	COG2888	peptidyl-tyrosine sulfation
EGX53_07045	COG1466	dna polymerase III delta subunit
EGX53_07055	COG0799	negative regulation of ribosome biogenesis
EGX53_07065	COG0768	penicillin binding
EGX53_07070	COG0772	Belongs to the SEDS family
EGX53_07075	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGX53_07080	COG1686	Belongs to the peptidase S11 family
EGX53_07105	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGX53_07110	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX53_07115	COG1278	Cold shock
EGX53_07120	COG1278	Cold shock
EGX53_07125	COG2197	response regulator
EGX53_07150	COG5265	(ABC) transporter
EGX53_07160	COG3718	enzyme involved in inositol metabolism
EGX53_07170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX53_07175	COG0673	inositol 2-dehydrogenase activity
EGX53_07180	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_07185	COG1129	ABC transporter
EGX53_07190	COG1879	ABC-type sugar transport system periplasmic component
EGX53_07195	COG0673	inositol 2-dehydrogenase activity
EGX53_07200	COG3962	Belongs to the TPP enzyme family
EGX53_07220	COG2373	Large extracellular alpha-helical protein
EGX53_07225	COG4953	penicillin-binding protein 1C
EGX53_07230	COG3423	Transcriptional regulator
EGX53_07280	COG2850	peptidyl-arginine hydroxylation
EGX53_07290	COG3328	transposase activity
EGX53_07295	COG1187	pseudouridine synthase activity
EGX53_07320	COG0656	L-ascorbic acid biosynthetic process
EGX53_07325	COG0667	Aldo Keto reductase
EGX53_07345	COG0671	phosphoesterase, PA-phosphatase related
EGX53_07345	COG2453	phosphatase
EGX53_07350	COG2267	carboxylic ester hydrolase activity
EGX53_07360	COG4589	Belongs to the CDS family
EGX53_07365	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGX53_07380	COG0582	viral genome integration into host DNA
EGX53_07560	COG4386	tail sheath protein
EGX53_07595	COG0582	viral genome integration into host DNA
EGX53_07620	COG2003	Belongs to the UPF0758 family
EGX53_07650	COG3596	GTP binding
EGX53_07705	COG0582	viral genome integration into host DNA
EGX53_07710	COG0582	viral genome integration into host DNA
EGX53_07725	COG2501	S4 domain
EGX53_07735	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX53_07750	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
EGX53_07755	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGX53_07760	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EGX53_07765	COG4181	ATPase activity
EGX53_07770	COG2755	lipolytic protein G-D-S-L family
EGX53_07775	COG0300	oxidoreductase activity
EGX53_07780	COG3118	belongs to the thioredoxin family
EGX53_07785	COG0330	HflC and HflK could
EGX53_07790	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGX53_07795	COG0789	Transcriptional regulator
EGX53_07800	COG2217	Heavy metal translocating P-type atpase
EGX53_07805	COG3735	TraB family
EGX53_07810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGX53_07820	COG0737	Belongs to the 5'-nucleotidase family
EGX53_07825	COG0737	Belongs to the 5'-nucleotidase family
EGX53_07835	COG1943	Transposase
EGX53_07845	COG4651	solute:proton antiporter activity
EGX53_07845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGX53_07850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX53_07855	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EGX53_07865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX53_07880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX53_07885	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
EGX53_07900	COG2244	polysaccharide biosynthetic process
EGX53_07910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGX53_07930	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX53_07930	COG0543	2 iron, 2 sulfur cluster binding
EGX53_07960	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGX53_07970	COG2832	Protein of unknown function (DUF454)
EGX53_07985	COG1196	nuclear chromosome segregation
EGX53_07985	COG3264	Mechanosensitive ion channel
EGX53_07990	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EGX53_07995	COG1309	transcriptional regulator
EGX53_08000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX53_08005	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX53_08015	COG1943	Transposase
EGX53_08025	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX53_08050	COG3695	enzyme binding
EGX53_08055	COG3126	Type III secretion system lipoprotein chaperone (YscW)
EGX53_08060	COG1946	Acyl-CoA thioesterase
EGX53_08065	COG0004	ammonium transporteR
EGX53_08070	COG0347	Belongs to the P(II) protein family
EGX53_08075	COG1132	(ABC) transporter
EGX53_08080	COG1132	(ABC) transporter
EGX53_08085	COG1522	sequence-specific DNA binding
EGX53_08100	COG4533	DNA binding
EGX53_08110	COG0824	Thioesterase
EGX53_08115	COG1555	photosystem II stabilization
EGX53_08120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX53_08125	COG0776	regulation of translation
EGX53_08130	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
EGX53_08155	COG0271	Belongs to the BolA IbaG family
EGX53_08160	COG3056	Lipoprotein
EGX53_08165	COG2223	nitrite transmembrane transporter activity
EGX53_08175	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGX53_08180	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGX53_08185	COG1845	cytochrome c oxidase, subunit III
EGX53_08190	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGX53_08200	COG2814	Major facilitator Superfamily
EGX53_08215	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
EGX53_08220	COG0693	protein deglycase activity
EGX53_08235	COG0142	geranyltranstransferase activity
EGX53_08245	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGX53_08250	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EGX53_08265	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX53_08265	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX53_08285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX53_08290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGX53_08295	COG1862	Preprotein translocase
EGX53_08315	COG0450	alkyl hydroperoxide reductase
EGX53_08330	COG0300	oxidoreductase activity
EGX53_08340	COG0366	Alpha amylase catalytic
EGX53_08350	COG1114	Component of the transport system for branched-chain amino acids
EGX53_08360	COG5002	protein histidine kinase activity
EGX53_08365	COG0745	RESPONSE REGULATOR receiver
EGX53_08370	COG0420	3'-5' exonuclease activity
EGX53_08375	COG0419	ATPase involved in DNA repair
EGX53_08380	COG1940	carbohydrate kinase activity
EGX53_08410	COG2226	methyltransferase
EGX53_08460	COG0583	DNA-binding transcription factor activity
EGX53_08465	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX53_08485	COG1477	protein flavinylation
EGX53_08505	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EGX53_08510	COG1805	sodium ion transport
EGX53_08515	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
EGX53_08525	COG3034	peptidoglycan biosynthetic process
EGX53_08530	COG0121	glutamine amidotransferase
EGX53_08540	COG1960	acyl-CoA dehydrogenase activity
EGX53_08550	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
EGX53_08570	COG1943	Transposase
EGX53_08600	COG0436	Aminotransferase
EGX53_08615	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EGX53_08665	COG2814	Major facilitator Superfamily
EGX53_08670	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGX53_08680	COG1846	Transcriptional regulator
EGX53_08685	COG1566	PFAM secretion protein HlyD family protein
EGX53_08690	COG2814	Major facilitator Superfamily
EGX53_08695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX53_08700	COG3118	belongs to the thioredoxin family
EGX53_08710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX53_08710	COG1042	CoA-binding domain protein
EGX53_08710	COG0045	succinate-CoA ligase (ADP-forming) activity
EGX53_08715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX53_08720	COG5544	Lipoprotein
EGX53_08760	COG0542	response to heat
EGX53_08770	COG0564	pseudouridine synthase activity
EGX53_08780	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX53_08785	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
EGX53_08790	COG0077	Prephenate dehydratase
EGX53_08790	COG1605	Chorismate mutase
EGX53_08795	COG0287	Prephenate dehydrogenase
EGX53_08795	COG1605	Chorismate mutase
EGX53_08800	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGX53_08805	COG3279	Response regulator of the LytR AlgR family
EGX53_08810	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EGX53_08815	COG3137	Salt-induced outer membrane protein
EGX53_08840	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGX53_08845	COG4137	Cytochrome C assembly protein
EGX53_08850	COG4536	flavin adenine dinucleotide binding
EGX53_08865	COG1238	metal cluster binding
EGX53_08870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX53_08900	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
EGX53_08945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX53_08950	COG3958	Transketolase
EGX53_08955	COG3959	Transketolase, thiamine diphosphate binding domain
EGX53_08960	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_08965	COG1129	ABC transporter
EGX53_08985	COG3783	Cytochrome b(562)
EGX53_08990	COG3038	cytochrome b561
EGX53_08995	COG3381	protein complex oligomerization
EGX53_09000	COG3302	dmso reductase anchor subunit
EGX53_09005	COG0437	4 iron, 4 sulfur cluster binding
EGX53_09010	COG0243	molybdopterin cofactor binding
EGX53_09015	COG0235	Class ii aldolase
EGX53_09020	COG1349	DNA-binding transcription factor activity
EGX53_09030	COG1129	ABC transporter
EGX53_09035	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_09040	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_09045	COG3623	hexulose-6-phosphate isomerase
EGX53_09050	COG1070	Carbohydrate kinase
EGX53_09055	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX53_09055	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX53_09065	COG0024	Methionine aminopeptidase
EGX53_09075	COG4771	TonB-dependent receptor
EGX53_09085	COG1858	cytochrome C peroxidase
EGX53_09090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX53_09110	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
EGX53_09125	COG2376	Dihydroxyacetone kinase
EGX53_09130	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_09135	COG1063	alcohol dehydrogenase
EGX53_09140	COG0698	ribose 5-phosphate isomerase
EGX53_09150	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGX53_09155	COG1388	LysM domain
EGX53_09155	COG4942	peptidase
EGX53_09195	COG0529	Catalyzes the synthesis of activated sulfate
EGX53_09245	COG0720	synthase
EGX53_09250	COG0602	queuosine metabolic process
EGX53_09270	COG3956	TIGRFAM MazG family protein
EGX53_09275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX53_09280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
EGX53_09290	COG3850	Histidine kinase
EGX53_09290	COG4999	Histidine kinase
EGX53_09290	COG2205	protein histidine kinase activity
EGX53_09290	COG3437	response regulator, receiver
EGX53_09295	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX53_09315	COG2860	membrane
EGX53_09335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX53_09340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
EGX53_09345	COG1120	ATPase activity
EGX53_09350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX53_09355	COG1643	Atp-dependent helicase
EGX53_09360	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
EGX53_09375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGX53_09385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGX53_09390	COG0617	tRNA 3'-terminal CCA addition
EGX53_09395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGX53_09415	COG0726	polysaccharide deacetylase
EGX53_09420	COG0842	Transport permease protein
EGX53_09425	COG1131	(ABC) transporter
EGX53_09430	COG0288	reversible hydration of carbon dioxide
EGX53_09435	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
EGX53_09440	COG2132	Multicopper oxidase
EGX53_09460	COG0697	spore germination
EGX53_09470	COG1049	propionate catabolic process, 2-methylcitrate cycle
EGX53_09485	COG1943	Transposase
EGX53_09490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX53_09495	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX53_09500	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
EGX53_09505	COG2186	Transcriptional regulator
EGX53_09515	COG1113	amino acid transport
EGX53_09520	COG3725	Membrane protein required for beta-lactamase induction
EGX53_09525	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX53_09535	COG4969	Belongs to the N-Me-Phe pilin family
EGX53_09540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX53_09545	COG1459	type II secretion system
EGX53_09560	COG0237	dephospho-CoA kinase activity
EGX53_09575	COG1943	Transposase
EGX53_09585	COG0494	nUDIX hydrolase
EGX53_09615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGX53_09620	COG0849	cell division
EGX53_09625	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGX53_09645	COG0772	Belongs to the SEDS family
EGX53_09660	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGX53_09665	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX53_09670	COG0768	penicillin binding
EGX53_09675	COG3116	cell division
EGX53_09700	COG1609	Transcriptional regulator
EGX53_09715	COG0028	Belongs to the TPP enzyme family
EGX53_09725	COG1022	Amp-dependent synthetase and ligase
EGX53_09750	COG0473	3-isopropylmalate dehydrogenase activity
EGX53_09765	COG2814	Major facilitator Superfamily
EGX53_09780	COG4143	(ABC) transporter
EGX53_09785	COG1178	ABC-type Fe3 transport system permease component
EGX53_09795	COG0586	Pfam SNARE associated Golgi protein
EGX53_09800	COG0417	DNA replication proofreading
EGX53_09820	COG2885	chlorophyll binding
EGX53_09820	COG3047	cAMP biosynthetic process
EGX53_09855	COG3501	Rhs element vgr protein
EGX53_09905	COG0564	pseudouridine synthase activity
EGX53_09910	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
EGX53_09920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX53_09960	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGX53_09970	COG2966	Psort location CytoplasmicMembrane, score
EGX53_09980	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
EGX53_09985	COG0505	Belongs to the CarA family
EGX53_10005	COG1047	Peptidyl-prolyl cis-trans
EGX53_10020	COG0196	riboflavin kinase activity
EGX53_10040	COG0583	DNA-binding transcription factor activity
EGX53_10060	COG1584	GPR1 FUN34 yaaH family protein
EGX53_10075	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGX53_10115	COG0745	RESPONSE REGULATOR receiver
EGX53_10120	COG3045	CreA protein
EGX53_10130	COG3708	Transcriptional regulator
EGX53_10130	COG2207	Transcriptional regulator
EGX53_10145	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
EGX53_10150	COG0741	lytic transglycosylase activity
EGX53_10165	COG2199	diguanylate cyclase activity
EGX53_10170	COG2885	chlorophyll binding
EGX53_10175	COG0488	(ABC) transporter
EGX53_10195	COG0560	Phosphoserine phosphatase
EGX53_10200	COG3726	membrane protein affecting hemolysin expression
EGX53_10220	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
EGX53_10225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX53_10230	COG0084	hydrolase, TatD family'
EGX53_10235	COG4667	esterase of the alpha-beta hydrolase superfamily
EGX53_10245	COG2823	Periplasmic or secreted lipoprotein
EGX53_10255	COG0456	acetyltransferase
EGX53_10260	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
EGX53_10290	COG3706	GGDEF domain
EGX53_10315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX53_10320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX53_10340	COG0859	PFAM glycosyl transferase family 9
EGX53_10350	COG2390	Transcriptional regulator
EGX53_10395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX53_10395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX53_10395	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX53_10400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX53_10405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX53_10410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX53_10415	COG2207	Transcriptional regulator
EGX53_10425	COG4269	membrane
EGX53_10480	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EGX53_10490	COG0582	viral genome integration into host DNA
EGX53_10500	COG0795	lipopolysaccharide-transporting ATPase activity
EGX53_10505	COG0795	lipopolysaccharide-transporting ATPase activity
EGX53_10515	COG2927	DNA polymerase III (CHI subunit)
EGX53_10530	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
EGX53_10540	COG2731	YhcH YjgK YiaL family protein
EGX53_10550	COG0601	transmembrane transport
EGX53_10555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX53_10560	COG0444	Belongs to the ABC transporter superfamily
EGX53_10565	COG4608	Belongs to the ABC transporter superfamily
EGX53_10585	COG2188	Transcriptional regulator
EGX53_10590	COG3624	Phosphonate C-P lyase system protein PhnG
EGX53_10595	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
EGX53_10600	COG3626	phosphonate metabolism
EGX53_10605	COG3627	carbon phosphorus lyase activity
EGX53_10610	COG4107	phosphonate C-P lyase system protein PhnK
EGX53_10615	COG4778	phosphonate C-P lyase system protein PhnL
EGX53_10620	COG3454	Phosphonate metabolism
EGX53_10625	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
EGX53_10630	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
EGX53_10635	COG0702	epimerase
EGX53_10650	COG3842	ATPase activity
EGX53_10655	COG0395	ABC-type sugar transport system, permease component
EGX53_10665	COG1653	transport
EGX53_10685	COG3153	acetyltransferase
EGX53_10715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX53_10725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX53_10745	COG0513	Belongs to the DEAD box helicase family
EGX53_10785	COG0195	Participates in both transcription termination and antitermination
EGX53_10805	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX53_10815	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGX53_10820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGX53_10830	COG1534	Rna-binding protein
EGX53_10835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX53_10840	COG2027	D-alanyl-D-alanine carboxypeptidase
EGX53_10845	COG0745	RESPONSE REGULATOR receiver
EGX53_10850	COG0642	Histidine kinase
EGX53_10910	COG0697	spore germination
EGX53_10925	COG0142	geranyltranstransferase activity
EGX53_10935	COG3423	Transcriptional regulator
EGX53_10960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGX53_10970	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGX53_10975	COG2105	PFAM AIG2 family protein
EGX53_10980	COG2911	Protein conserved in bacteria
EGX53_10985	COG0729	surface antigen
EGX53_10995	COG1253	flavin adenine dinucleotide binding
EGX53_11005	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
EGX53_11015	COG0737	Belongs to the 5'-nucleotidase family
EGX53_11025	COG0545	Peptidyl-prolyl cis-trans isomerase
EGX53_11030	COG3061	Opacity-associated protein A
EGX53_11045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
EGX53_11055	COG0360	Binds together with S18 to 16S ribosomal RNA
EGX53_11065	COG1073	alpha beta
EGX53_11070	COG3650	response to hydrogen peroxide
EGX53_11075	COG1960	acyl-CoA dehydrogenase activity
EGX53_11080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX53_11085	COG0557	exoribonuclease II activity
EGX53_11100	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
EGX53_11105	COG0330	HflC and HflK could
EGX53_11110	COG0330	HflC and HflK could
EGX53_11115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGX53_11135	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX53_11140	COG0802	atpase or kinase
EGX53_11145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGX53_11145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGX53_11150	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGX53_11195	COG3264	Mechanosensitive ion channel
EGX53_11195	COG1511	domain protein
EGX53_11210	COG1053	succinate dehydrogenase
EGX53_11215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGX53_11225	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
EGX53_11230	COG2076	Multidrug Resistance protein
EGX53_11275	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
EGX53_11290	COG3383	formate dehydrogenase (NAD+) activity
EGX53_11295	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX53_11300	COG0493	'glutamate synthase
EGX53_11300	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX53_11310	COG1309	transcriptional regulator
EGX53_11380	COG1454	alcohol dehydrogenase
EGX53_11390	COG0629	single-stranded DNA binding
EGX53_11400	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX53_11405	COG2315	Protein conserved in bacteria
EGX53_11410	COG1448	Aminotransferase
EGX53_11415	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGX53_11420	COG0305	Participates in initiation and elongation during chromosome replication
EGX53_11435	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX53_11440	COG0735	belongs to the Fur family
EGX53_11450	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
EGX53_11505	COG3121	Chaperone
EGX53_11565	COG1358	cellular component organization or biogenesis
EGX53_11590	COG3721	Heme iron utilization protein
EGX53_11595	COG0702	epimerase
EGX53_11605	COG4771	TonB-dependent receptor
EGX53_11610	COG3720	iron ion transport
EGX53_11615	COG4558	Periplasmic binding protein
EGX53_11620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX53_11630	COG0626	cystathionine gamma-synthase activity
EGX53_11635	COG0814	amino acid
EGX53_11640	COG0583	DNA-binding transcription factor activity
EGX53_11645	COG0425	Belongs to the sulfur carrier protein TusA family
EGX53_11650	COG2391	methyltransferase activity
EGX53_11765	COG1301	dicarboxylic acid transport
EGX53_11775	COG3162	membrane
EGX53_11830	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
EGX53_11835	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGX53_11840	COG1739	Uncharacterized protein family UPF0029
EGX53_11885	COG0805	protein transport
EGX53_11895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGX53_11915	COG1322	Protein conserved in bacteria
EGX53_11920	COG0586	Pfam SNARE associated Golgi protein
EGX53_11925	COG1966	Carbon starvation protein
EGX53_11935	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
EGX53_11940	COG0412	Dienelactone hydrolase
EGX53_11950	COG0583	DNA-binding transcription factor activity
EGX53_11970	COG0679	Auxin Efflux Carrier
EGX53_11975	COG0584	glycerophosphoryl diester phosphodiesterase
EGX53_12035	COG0410	ABC transporter
EGX53_12040	COG0411	ABC transporter
EGX53_12045	COG4177	L-phenylalanine transmembrane transporter activity
EGX53_12050	COG0559	Belongs to the binding-protein-dependent transport system permease family
EGX53_12055	COG0683	leucine binding
EGX53_12070	COG2177	Part of the ABC transporter FtsEX involved in
EGX53_12075	COG2884	Cell division ATP-binding protein ftsE
EGX53_12080	COG0552	protein localization to endoplasmic reticulum
EGX53_12080	COG0552	protein localization to endoplasmic reticulum
EGX53_12090	COG0742	ribosomal rna small subunit methyltransferase
EGX53_12095	COG3776	membrane
EGX53_12110	COG3714	YhhN family
EGX53_12125	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
EGX53_12135	COG0247	lactate metabolic process
EGX53_12145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX53_12160	COG0584	glycerophosphoryl diester phosphodiesterase
EGX53_12170	COG0561	phosphatase activity
EGX53_12175	COG2267	carboxylic ester hydrolase activity
EGX53_12180	COG1280	lysine exporter protein (LysE YggA)
EGX53_12185	COG1280	lysine exporter protein (LysE YggA)
EGX53_12190	COG0514	ATP-dependent DNA helicase (RecQ)
EGX53_12195	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
EGX53_12200	COG2050	protein possibly involved in aromatic compounds catabolism
EGX53_12210	COG0598	Magnesium transport protein CorA
EGX53_12215	COG5564	TIM-barrel signal transduction protein
EGX53_12220	COG5441	Belongs to the UPF0261 family
EGX53_12230	COG0210	DNA helicase
EGX53_12235	COG1011	Hydrolase
EGX53_12240	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGX53_12245	COG3159	Protein conserved in bacteria
EGX53_12255	COG5567	small periplasmic lipoprotein
EGX53_12265	COG3072	Adenylate cyclase
EGX53_12280	COG1587	Uroporphyrinogen-III synthase
EGX53_12285	COG2959	enzyme of heme biosynthesis
EGX53_12290	COG3071	HemY protein
EGX53_12320	COG1113	amino acid transport
EGX53_12340	COG2244	polysaccharide biosynthetic process
EGX53_12345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGX53_12350	COG0456	acetyltransferase
EGX53_12355	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
EGX53_12360	COG1088	dTDP-glucose 4,6-dehydratase activity
EGX53_12365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGX53_12370	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGX53_12375	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
EGX53_12380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGX53_12385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
EGX53_12390	COG3118	belongs to the thioredoxin family
EGX53_12415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX53_12435	COG3121	Chaperone
EGX53_12450	COG3121	Chaperone
EGX53_12490	COG0583	DNA-binding transcription factor activity
EGX53_12520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX53_12525	COG3978	acetolactate synthase activity
EGX53_12550	COG3085	chromosome segregation
EGX53_12560	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_12565	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_12570	COG1129	ABC transporter
EGX53_12575	COG1879	ABC-type sugar transport system periplasmic component
EGX53_12655	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX53_12655	COG0678	peroxiredoxin activity
EGX53_12660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX53_12685	COG1629	transport
EGX53_12730	COG0460	homoserine dehydrogenase
EGX53_12730	COG0527	aspartate kinase activity
EGX53_12735	COG0626	cystathionine gamma-synthase activity
EGX53_12740	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
EGX53_12745	COG4682	membrane
EGX53_12755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGX53_12765	COG1609	Transcriptional regulator
EGX53_12770	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGX53_12785	COG1575	Belongs to the MenA family. Type 1 subfamily
EGX53_12840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
EGX53_12845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX53_12850	COG1494	fructose-1,6-bisphosphatase
EGX53_12860	COG3152	Membrane
EGX53_12875	COG0583	DNA-binding transcription factor activity
EGX53_12880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
EGX53_12885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGX53_12890	COG0471	metal ion transport
EGX53_12900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGX53_12930	COG3678	ATP-independent chaperone mediated protein folding
EGX53_12935	COG0745	RESPONSE REGULATOR receiver
EGX53_12940	COG2205	protein histidine kinase activity
EGX53_12945	COG2169	Transcriptional regulator
EGX53_12945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX53_12950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGX53_12955	COG1045	serine acetyltransferase
EGX53_12975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX53_12980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
EGX53_12990	COG4942	peptidase
EGX53_12995	COG2861	carbohydrate metabolic process
EGX53_13005	COG0156	8-amino-7-oxononanoate synthase activity
EGX53_13015	COG0859	PFAM glycosyl transferase family 9
EGX53_13020	COG0859	PFAM glycosyl transferase family 9
EGX53_13025	COG1519	Transferase
EGX53_13045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
EGX53_13065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGX53_13090	COG1561	YicC-like family, N-terminal region
EGX53_13145	COG2860	membrane
EGX53_13150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
EGX53_13160	COG1758	RNA polymerase activity
EGX53_13165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX53_13170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX53_13175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX53_13185	COG0786	glutamate:sodium symporter activity
EGX53_13190	COG2233	PERMEase
EGX53_13195	COG2982	Protein involved in outer membrane biogenesis
EGX53_13200	COG0456	acetyltransferase
EGX53_13215	COG1011	Hydrolase
EGX53_13225	COG0174	glutamine synthetase
EGX53_13235	COG3852	Histidine kinase
EGX53_13245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX53_13270	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX53_13270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
EGX53_13275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX53_13280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EGX53_13285	COG3084	Protein conserved in bacteria
EGX53_13295	COG1763	Mo-molybdopterin cofactor biosynthetic process
EGX53_13300	COG3328	transposase activity
EGX53_13335	COG2186	Transcriptional regulator
EGX53_13340	COG0477	Major facilitator Superfamily
EGX53_13350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX53_13380	COG1522	sequence-specific DNA binding
EGX53_13385	COG0716	FMN binding
EGX53_13405	COG3312	ion transport
EGX53_13460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGX53_13465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGX53_13470	COG0573	inorganic phosphate transmembrane transporter activity
EGX53_13475	COG0581	inorganic phosphate transmembrane transporter activity
EGX53_13485	COG0704	Plays a role in the regulation of phosphate uptake
EGX53_13495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX53_13500	COG0765	amino acid transport
EGX53_13505	COG0765	amino acid transport
EGX53_13510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX53_13520	COG2252	PERMEase
EGX53_13550	COG0706	membrane insertase activity
EGX53_13565	COG0230	Belongs to the bacterial ribosomal protein bL34 family
EGX53_13585	COG0592	DNA-directed DNA polymerase activity
EGX53_13590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGX53_13595	COG0187	DNA topoisomerase II activity
EGX53_13600	COG0561	phosphatase activity
EGX53_13610	COG2423	ornithine cyclodeaminase activity
EGX53_13615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGX53_13620	COG0823	Involved in the tonB-independent uptake of proteins
EGX53_13625	COG5645	(Lipo)protein
EGX53_13645	COG3977	Valine--pyruvate aminotransferase
EGX53_13665	COG0366	Alpha amylase catalytic
EGX53_13685	COG2885	chlorophyll binding
EGX53_13695	COG2818	Glycosylase
EGX53_13725	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX53_13725	COG2213	PTS system mannitol-specific
EGX53_13735	COG3722	fumarate hydratase activity
EGX53_13760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGX53_13770	COG3383	formate dehydrogenase (NAD+) activity
EGX53_13770	COG0243	molybdopterin cofactor binding
EGX53_13775	COG0243	molybdopterin cofactor binding
EGX53_13775	COG3383	formate dehydrogenase (NAD+) activity
EGX53_13780	COG0437	4 iron, 4 sulfur cluster binding
EGX53_13785	COG2864	formate dehydrogenase
EGX53_13800	COG3276	selenocysteine insertion sequence binding
EGX53_13845	COG3274	enterobacterial common antigen metabolic process
EGX53_13855	COG3188	usher protein
EGX53_13860	COG3121	Chaperone
EGX53_13870	COG1070	Carbohydrate kinase
EGX53_13880	COG4213	ABC transporter substrate-binding protein
EGX53_13890	COG4214	carbohydrate transport
EGX53_13895	COG2207	Transcriptional regulator
EGX53_13895	COG1609	Transcriptional regulator
EGX53_13900	COG0582	viral genome integration into host DNA
EGX53_13930	COG4604	ABC transporter, ATP-binding protein
EGX53_13935	COG4605	iron ion homeostasis
EGX53_13945	COG4607	ABC-type enterochelin transport system periplasmic component
EGX53_13960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
EGX53_13990	COG2194	sulfuric ester hydrolase activity
EGX53_13995	COG2197	response regulator
EGX53_14000	COG3851	Histidine kinase
EGX53_14005	COG2271	Major facilitator Superfamily
EGX53_14020	COG2831	hemolysin activation secretion protein
EGX53_14030	COG0747	negative chemotaxis
EGX53_14035	COG0601	transmembrane transport
EGX53_14040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX53_14045	COG0444	Belongs to the ABC transporter superfamily
EGX53_14050	COG4608	Belongs to the ABC transporter superfamily
EGX53_14060	COG2199	diguanylate cyclase activity
EGX53_14060	COG2200	EAL domain
EGX53_14065	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
EGX53_14090	COG0612	Peptidase, M16
EGX53_14095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX53_14100	COG1942	4-Oxalocrotonate Tautomerase
EGX53_14105	COG2200	EAL domain
EGX53_14110	COG2982	Protein involved in outer membrane biogenesis
EGX53_14115	COG2134	cdp-diacylglycerol pyrophosphatase
EGX53_14120	COG1295	ribonuclease BN
EGX53_14145	COG1929	Belongs to the glycerate kinase type-1 family
EGX53_14150	COG2610	gluconate transmembrane transporter activity
EGX53_14160	COG3835	regulator
EGX53_14165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX53_14170	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGX53_14175	COG0339	signal peptide processing
EGX53_14195	COG0589	response to stress
EGX53_14205	COG0306	phosphate transporter
EGX53_14210	COG2081	HI0933 family
EGX53_14225	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_14230	COG1879	ABC-type sugar transport system periplasmic component
EGX53_14240	COG0191	fructose-bisphosphate aldolase activity
EGX53_14250	COG0745	RESPONSE REGULATOR receiver
EGX53_14265	COG1741	Belongs to the pirin family
EGX53_14270	COG1609	Transcriptional regulator
EGX53_14275	COG2610	gluconate transmembrane transporter activity
EGX53_14280	COG3265	gluconokinase activity
EGX53_14300	COG2095	MarC family integral membrane protein
EGX53_14305	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX53_14330	COG3275	phosphorelay sensor kinase activity
EGX53_14355	COG0058	SHG alpha-glucan phosphorylase activity
EGX53_14360	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
EGX53_14390	COG1349	DNA-binding transcription factor activity
EGX53_14410	COG0058	SHG alpha-glucan phosphorylase activity
EGX53_14415	COG1640	4-alpha-glucanotransferase
EGX53_14450	COG1918	ferrous iron import across plasma membrane
EGX53_14455	COG2183	response to ionizing radiation
EGX53_14460	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX53_14465	COG0745	RESPONSE REGULATOR receiver
EGX53_14485	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGX53_14490	COG1011	Hydrolase
EGX53_14500	COG0494	nUDIX hydrolase
EGX53_14585	COG3179	chitinase
EGX53_14600	COG4382	Mu-like prophage protein Gp16
EGX53_14675	COG3423	Transcriptional regulator
EGX53_14685	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
EGX53_14715	COG4796	Type ii and iii secretion system protein
EGX53_14740	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGX53_14745	COG0546	phosphoglycolate phosphatase activity
EGX53_14750	COG0180	Tryptophanyl-tRNA synthetase
EGX53_14765	COG2146	nitrite reductase [NAD(P)H] activity
EGX53_14770	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX53_14775	COG0402	S-adenosylhomocysteine deaminase activity
EGX53_14795	COG1486	melibiose metabolic process
EGX53_14800	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX53_14805	COG0433	COG0433 Predicted ATPase
EGX53_14820	COG1289	transmembrane transporter activity
EGX53_14830	COG1765	OsmC-like protein
EGX53_14835	COG3157	Type VI secretion system effector, Hcp
EGX53_14850	COG3954	Phosphoribulokinase
EGX53_14860	COG0429	hydrolase of the alpha beta-hydrolase fold
EGX53_14870	COG4521	taurine ABC transporter
EGX53_14880	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX53_14885	COG2175	clavaminate synthase activity
EGX53_14895	COG1216	Glycosyl transferase, family 2
EGX53_14900	COG0488	(ABC) transporter
EGX53_14905	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGX53_14915	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EGX53_14920	COG1047	Peptidyl-prolyl cis-trans
EGX53_14935	COG0545	Peptidyl-prolyl cis-trans isomerase
EGX53_14940	COG2964	Protein conserved in bacteria
EGX53_14960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
EGX53_14965	COG0049	tRNA binding
EGX53_14985	COG1943	Transposase
EGX53_15005	COG0051	transcription antitermination factor activity, RNA binding
EGX53_15030	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
EGX53_15040	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
EGX53_15045	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
EGX53_15055	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
EGX53_15060	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
EGX53_15100	COG1841	ribosomal large subunit assembly
EGX53_15110	COG0201	protein transport
EGX53_15115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
EGX53_15130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
EGX53_15145	COG0789	Transcriptional regulator
EGX53_15150	COG3036	rescue of stalled ribosome
EGX53_15160	COG0569	domain protein
EGX53_15180	COG0758	DNA mediated transformation
EGX53_15190	COG0551	DNA topoisomerase type I activity
EGX53_15205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGX53_15285	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
EGX53_15290	COG0250	Participates in transcription elongation, termination and antitermination
EGX53_15345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
EGX53_15355	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
EGX53_15380	COG1515	deoxyribonuclease V activity
EGX53_15385	COG3068	Protein conserved in bacteria
EGX53_15400	COG0151	Belongs to the GarS family
EGX53_15460	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGX53_15465	COG2224	Isocitrate lyase
EGX53_15475	COG1414	Transcriptional regulator
EGX53_15490	COG0527	aspartate kinase activity
EGX53_15505	COG3833	ABC-type maltose transport systems, permease component
EGX53_15510	COG1175	transmembrane transport
EGX53_15630	COG3501	Rhs element vgr protein
EGX53_15690	COG3501	Rhs element vgr protein
EGX53_15705	COG0673	inositol 2-dehydrogenase activity
EGX53_15710	COG2207	Transcriptional regulator
EGX53_15715	COG1869	D-ribose catabolic process
EGX53_15720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX53_15735	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGX53_15745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX53_15760	COG3077	Addiction module antitoxin, RelB DinJ family
EGX53_15765	COG2252	PERMEase
EGX53_15770	COG3328	transposase activity
EGX53_15775	COG0025	NhaP-type Na H and K H
EGX53_15785	COG1560	Kdo2-lipid A biosynthetic process
EGX53_15795	COG1129	ABC transporter
EGX53_15800	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_15810	COG1069	ribulokinase activity
EGX53_15820	COG0625	glutathione transferase activity
EGX53_15835	COG1278	Cold shock
EGX53_15840	COG1278	Cold shock
EGX53_15845	COG1278	Cold shock
EGX53_15855	COG3133	Outer membrane lipoprotein
EGX53_15860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX53_15870	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX53_15900	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EGX53_15905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX53_15915	COG4145	pantothenate transmembrane transporter activity
EGX53_15920	COG3924	membrane
EGX53_15925	COG0439	Biotin carboxylase
EGX53_15930	COG0511	ligase activity, forming carbon-carbon bonds
EGX53_15950	COG0604	alcohol dehydrogenase
EGX53_15955	COG2200	EAL domain
EGX53_15955	COG2199	diguanylate cyclase activity
EGX53_15960	COG1077	Cell shape determining protein MreB Mrl
EGX53_15965	COG1792	Involved in formation and maintenance of cell shape
EGX53_15970	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EGX53_15980	COG1530	ribonuclease E activity
EGX53_15985	COG3164	Protein of unknown function
EGX53_15990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX53_15995	COG0312	modulator of DNA gyrase
EGX53_16040	COG0583	DNA-binding transcription factor activity
EGX53_16070	COG2732	(Barnase) inhibitor
EGX53_16080	COG0312	modulator of DNA gyrase
EGX53_16090	COG3783	Cytochrome b(562)
EGX53_16095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX53_16100	COG0366	Alpha amylase catalytic
EGX53_16105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX53_16105	COG1263	PTS System
EGX53_16110	COG1609	Transcriptional regulator
EGX53_16140	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX53_16155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX53_16165	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
EGX53_16170	COG1137	ATPase activity
EGX53_16175	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EGX53_16180	COG3117	lipopolysaccharide transmembrane transporter activity
EGX53_16185	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGX53_16190	COG0517	IMP dehydrogenase activity
EGX53_16190	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGX53_16195	COG0530	calcium, potassium:sodium antiporter activity
EGX53_16200	COG1127	ABC transporter
EGX53_16205	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGX53_16210	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGX53_16215	COG2854	intermembrane phospholipid transfer
EGX53_16220	COG3113	response to antibiotic
EGX53_16225	COG5007	Belongs to the BolA IbaG family
EGX53_16235	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX53_16240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX53_16245	COG3105	Protein conserved in bacteria
EGX53_16250	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGX53_16270	COG0625	glutathione transferase activity
EGX53_16275	COG2969	positive regulation of protein catabolic process
EGX53_16285	COG0493	'glutamate synthase
EGX53_16290	COG0070	glutamate synthase
EGX53_16290	COG0067	glutamate synthase
EGX53_16290	COG0069	glutamate synthase activity
EGX53_16295	COG1242	4 iron, 4 sulfur cluster binding
EGX53_16305	COG5002	protein histidine kinase activity
EGX53_16305	COG0784	Response regulator, receiver
EGX53_16305	COG2198	Histidine kinase
EGX53_16315	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
EGX53_16325	COG2823	Periplasmic or secreted lipoprotein
EGX53_16345	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
EGX53_16355	COG1741	Belongs to the pirin family
EGX53_16360	COG0583	DNA-binding transcription factor activity
EGX53_16370	COG2259	Doxx family
EGX53_16380	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
EGX53_16385	COG4575	ribosome binding
EGX53_16405	COG0586	Pfam SNARE associated Golgi protein
EGX53_16420	COG2271	Major facilitator Superfamily
EGX53_16430	COG0246	Mannitol dehydrogenase
EGX53_16435	COG2721	sulfolactate sulfo-lyase activity
EGX53_16450	COG0673	inositol 2-dehydrogenase activity
EGX53_16455	COG1451	nucleotide metabolic process
EGX53_16470	COG1902	pentaerythritol trinitrate reductase activity
EGX53_16470	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX53_16475	COG3247	response to pH
EGX53_16510	COG4245	von Willebrand factor, type A
EGX53_16515	COG2831	hemolysin activation secretion protein
EGX53_16545	COG3210	domain, Protein
EGX53_16555	COG3210	domain, Protein
EGX53_16560	COG3210	domain, Protein
EGX53_16575	COG3210	domain, Protein
EGX53_16580	COG3210	domain, Protein
EGX53_16600	COG3842	ATPase activity
EGX53_16605	COG3459	Glycosyltransferase 36 associated
EGX53_16610	COG1609	Transcriptional regulator
EGX53_16615	COG1653	transport
EGX53_16625	COG0395	ABC-type sugar transport system, permease component
EGX53_16645	COG1289	transmembrane transporter activity
EGX53_16690	COG0251	oxidation-reduction process
EGX53_16730	COG3157	Type VI secretion system effector, Hcp
EGX53_16765	COG3561	AntA/AntB antirepressor
EGX53_16865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
EGX53_16870	COG0358	DNA primase activity
EGX53_16890	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
EGX53_16905	COG4991	sh3 domain protein
EGX53_16910	COG3025	triphosphatase activity
EGX53_16925	COG0531	amino acid
EGX53_16945	COG3384	dioxygenase
EGX53_16950	COG0754	glutathionylspermidine amidase activity
EGX53_16965	COG1538	Outer membrane efflux protein
EGX53_16970	COG0494	nUDIX hydrolase
EGX53_16975	COG3151	Protein conserved in bacteria
EGX53_16980	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGX53_16985	COG3150	esterase
EGX53_16990	COG0187	DNA topoisomerase II activity
EGX53_16995	COG0583	DNA-binding transcription factor activity
EGX53_17000	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGX53_17010	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
EGX53_17015	COG0204	Acyl-transferase
EGX53_17025	COG2132	Multicopper oxidase
EGX53_17040	COG0656	L-ascorbic acid biosynthetic process
EGX53_17050	COG1979	alcohol dehydrogenase
EGX53_17055	COG2207	Transcriptional regulator
EGX53_17060	COG0586	Pfam SNARE associated Golgi protein
EGX53_17065	COG0626	cystathionine gamma-synthase activity
EGX53_17070	COG0811	peptide transport
EGX53_17075	COG0848	biopolymer transport protein
EGX53_17130	COG4964	Belongs to the GSP D family
EGX53_17160	COG3397	chitin binding
EGX53_17165	COG3469	chitinase activity
EGX53_17190	COG4592	Periplasmic binding protein
EGX53_17210	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
EGX53_17215	COG1684	flagellar biosynthetic protein fliR
EGX53_17220	COG1987	bacterial-type flagellum assembly
EGX53_17240	COG2204	response regulator
EGX53_17285	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
EGX53_17290	COG1815	bacterial-type flagellum-dependent cell motility
EGX53_17295	COG1558	bacterial-type flagellum-dependent cell motility
EGX53_17300	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
EGX53_17370	COG3133	Outer membrane lipoprotein
EGX53_17380	COG3300	MHYT domain
EGX53_17380	COG5001	Diguanylate cyclase
EGX53_17390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX53_17450	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
EGX53_17455	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX53_17460	COG4771	TonB-dependent receptor
EGX53_17465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX53_17465	COG2226	methyltransferase
EGX53_17465	COG3433	isochorismatase activity
EGX53_17470	COG3433	isochorismatase activity
EGX53_17470	COG2226	methyltransferase
EGX53_17470	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX53_17500	COG1132	(ABC) transporter
EGX53_17520	COG2610	gluconate transmembrane transporter activity
EGX53_17530	COG3501	Rhs element vgr protein
EGX53_17605	COG0471	metal ion transport
EGX53_17610	COG1609	Transcriptional regulator
EGX53_17620	COG2211	Major facilitator Superfamily
EGX53_17670	COG2771	luxR family
EGX53_17675	COG3916	Acyl-homoserine-lactone synthase
EGX53_17780	COG1982	Orn Lys Arg decarboxylase major
EGX53_17785	COG1879	ABC-type sugar transport system periplasmic component
EGX53_17790	COG1129	ABC transporter
EGX53_17795	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_17800	COG4774	siderophore transport
EGX53_17825	COG1194	a g-specific adenine glycosylase
EGX53_17835	COG3171	Protein conserved in bacteria
EGX53_17840	COG2066	Belongs to the glutaminase family
EGX53_17850	COG3064	Membrane
EGX53_17850	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
EGX53_17850	COG1073	alpha beta
EGX53_17855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX53_17860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
EGX53_17870	COG0762	integral membrane protein
EGX53_17875	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
EGX53_17880	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
EGX53_17885	COG2805	Type II/IV secretion system protein
EGX53_17895	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX53_17910	COG0189	ligase activity
EGX53_17915	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGX53_17925	COG2356	endonuclease I
EGX53_17940	COG1166	arginine decarboxylase activity
EGX53_17950	COG1943	Transposase
EGX53_17960	COG1943	Transposase
EGX53_17965	COG0501	Belongs to the peptidase M48B family
EGX53_17975	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGX53_17990	COG0191	fructose-bisphosphate aldolase activity
EGX53_18020	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
EGX53_18025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGX53_18030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGX53_18055	COG0006	proline dipeptidase activity
EGX53_18060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX53_18065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX53_18100	COG5295	Hep Hag repeat protein
EGX53_18110	COG1272	protein, Hemolysin III
EGX53_18125	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EGX53_18135	COG0745	RESPONSE REGULATOR receiver
EGX53_18140	COG2205	protein histidine kinase activity
EGX53_18145	COG4452	Inner membrane protein CreD
EGX53_18150	COG0716	FMN binding
EGX53_18155	COG4974	Belongs to the 'phage' integrase family
EGX53_18160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX53_18165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGX53_18185	COG0582	viral genome integration into host DNA
EGX53_18370	COG1695	Transcriptional regulator
EGX53_18375	COG0791	NLP P60 protein
EGX53_18385	COG1879	ABC-type sugar transport system periplasmic component
EGX53_18390	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_18395	COG1129	ABC transporter
EGX53_18405	COG2182	Extracellular solute-binding protein
EGX53_18410	COG1175	transmembrane transport
EGX53_18415	COG3833	ABC-type maltose transport systems, permease component
EGX53_18420	COG3867	Arabinogalactan endo-beta-1,4-galactanase
EGX53_18425	COG1874	Beta-galactosidase
EGX53_18430	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX53_18430	COG1263	PTS System
EGX53_18450	COG2271	Major facilitator Superfamily
EGX53_18470	COG0191	fructose-bisphosphate aldolase activity
EGX53_18480	COG3119	arylsulfatase activity
EGX53_18485	COG0641	radical SAM
EGX53_18495	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_18505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX53_18510	COG3716	PTS system mannose fructose sorbose family IID component
EGX53_18515	COG3715	PTS system
EGX53_18520	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX53_18525	COG2222	sugar isomerase
EGX53_18535	COG1349	DNA-binding transcription factor activity
EGX53_18540	COG3119	arylsulfatase activity
EGX53_18570	COG0288	reversible hydration of carbon dioxide
EGX53_18615	COG2165	general secretion pathway protein
EGX53_18655	COG0840	transmembrane signaling receptor activity
EGX53_18675	COG2814	Major facilitator Superfamily
EGX53_18680	COG0583	DNA-binding transcription factor activity
EGX53_18685	COG0019	diaminopimelate decarboxylase activity
EGX53_18690	COG1609	Transcriptional regulator
EGX53_18720	COG0667	Aldo Keto reductase
EGX53_18785	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGX53_18795	COG1074	ATP-dependent DNA helicase activity
EGX53_18800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX53_18810	COG0860	N-Acetylmuramoyl-L-alanine amidase
EGX53_18830	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
EGX53_18835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGX53_18840	COG2166	iron-sulfur cluster assembly
EGX53_18845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGX53_18855	COG0583	DNA-binding transcription factor activity
EGX53_18860	COG2363	Small membrane protein
EGX53_18880	COG1611	Belongs to the LOG family
EGX53_18895	COG3098	single-species biofilm formation
EGX53_18900	COG0564	pseudouridine synthase activity
EGX53_18925	COG0024	Methionine aminopeptidase
EGX53_18960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGX53_18965	COG0575	Belongs to the CDS family
EGX53_18970	COG0750	zinc metalloprotease
EGX53_18980	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
EGX53_19000	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGX53_19010	COG0587	DNA-directed DNA polymerase activity
EGX53_19020	COG0346	lactoylglutathione lyase activity
EGX53_19035	COG4568	rho-dependent transcription termination
EGX53_19045	COG4681	YaeQ
EGX53_19055	COG3015	lipoprotein NlpE involved in copper resistance
EGX53_19065	COG1720	tRNA m6t6A37 methyltransferase activity
EGX53_19075	COG1464	Belongs to the NlpA lipoprotein family
EGX53_19080	COG2011	ABC-type metal ion transport system permease component
EGX53_19090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
EGX53_19125	COG0656	L-ascorbic acid biosynthetic process
EGX53_19145	COG0741	lytic transglycosylase activity
EGX53_19145	COG1388	LysM domain
EGX53_19155	COG2226	methyltransferase
EGX53_19165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGX53_19175	COG1953	Uracil, thiamine, allantoin
EGX53_19185	COG2113	Glycine betaine
EGX53_19190	COG4176	ABC-type proline glycine betaine transport system permease component
EGX53_19195	COG4175	Glycine betaine
EGX53_19200	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX53_19240	COG1278	Cold shock
EGX53_19245	COG0747	negative chemotaxis
EGX53_19255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX53_19260	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
EGX53_19265	COG1124	(ABC) transporter
EGX53_19295	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
EGX53_19305	COG4413	Urea transporter
EGX53_19310	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
EGX53_19325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGX53_19330	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
EGX53_19345	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX53_19350	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
EGX53_19355	COG1447	Phosphotransferase system cellobiose-specific component IIA
EGX53_19360	COG2169	Transcriptional regulator
EGX53_19360	COG1917	Cupin 2, conserved barrel domain protein
EGX53_19385	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
EGX53_19390	COG0033	Phosphoglucomutase
EGX53_19405	COG0745	RESPONSE REGULATOR receiver
EGX53_19415	COG2205	protein histidine kinase activity
EGX53_19455	COG3272	Protein of unknown function (DUF1722)
EGX53_19465	COG5212	phosphodiesterase
EGX53_19470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGX53_19475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
EGX53_19480	COG1984	allophanate hydrolase subunit 2
EGX53_19525	COG0513	Belongs to the DEAD box helicase family
EGX53_19535	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
EGX53_19545	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
EGX53_19550	COG3026	antisigma factor binding
EGX53_19555	COG3086	response to oxidative stress
EGX53_19570	COG0681	Belongs to the peptidase S26 family
EGX53_19590	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGX53_19600	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX53_19605	COG1737	Transcriptional regulator
EGX53_19615	COG0560	Phosphoserine phosphatase
EGX53_19620	COG0590	tRNA wobble adenosine to inosine editing
EGX53_19650	COG2205	protein histidine kinase activity
EGX53_19655	COG3170	Tfp pilus assembly protein FimV
EGX53_19660	COG2204	response regulator
EGX53_19665	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX53_19665	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGX53_19670	COG0347	Belongs to the P(II) protein family
EGX53_19675	COG2188	Transcriptional regulator
EGX53_19680	COG1017	nitric oxide dioxygenase activity
EGX53_19680	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX53_19700	COG2814	Major facilitator Superfamily
EGX53_19705	COG3711	transcriptional antiterminator
EGX53_19710	COG3683	transport system, periplasmic component
EGX53_19715	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
EGX53_19720	COG0483	inositol monophosphate 1-phosphatase activity
EGX53_19735	COG1104	cysteine desulfurase activity
EGX53_19740	COG0822	iron-sulfur transferase activity
EGX53_19765	COG0633	Ferredoxin
EGX53_19770	COG2975	iron-sulfur cluster assembly
EGX53_19840	COG2976	Protein conserved in bacteria
EGX53_19845	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX53_19860	COG1645	bacterial-type flagellum-dependent swarming motility
EGX53_19870	COG0517	IMP dehydrogenase activity
EGX53_19870	COG0516	GMP reductase activity
EGX53_19945	COG0351	phosphomethylpyrimidine kinase
EGX53_19975	COG3422	double-strand break repair
EGX53_19980	COG0745	RESPONSE REGULATOR receiver
EGX53_19985	COG2205	protein histidine kinase activity
EGX53_20010	COG3842	ATPase activity
EGX53_20020	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGX53_20030	COG1176	ABC-type spermidine putrescine transport system, permease component I
EGX53_20035	COG1177	transmembrane transport
EGX53_20040	COG0443	Heat shock 70 kDa protein
EGX53_20045	COG2239	Acts as a magnesium transporter
EGX53_20055	COG0248	Ppx GppA phosphatase
EGX53_20060	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
EGX53_20070	COG0581	inorganic phosphate transmembrane transporter activity
EGX53_20085	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
EGX53_20090	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGX53_20105	COG2233	PERMEase
EGX53_20115	COG1393	Belongs to the ArsC family
EGX53_20120	COG4783	chaperone-mediated protein folding
EGX53_20125	COG0628	permease
EGX53_20140	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGX53_20145	COG2716	regulation of RNA biosynthetic process
EGX53_20155	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
EGX53_20165	COG2321	neutral zinc metallopeptidase
EGX53_20185	COG1876	peptidase activity
EGX53_20195	COG1393	Belongs to the ArsC family
EGX53_20205	COG1840	ABC-type Fe3 transport system, periplasmic component
EGX53_20210	COG1175	transmembrane transport
EGX53_20215	COG3842	ATPase activity
EGX53_20225	COG3119	arylsulfatase activity
EGX53_20230	COG0641	radical SAM
EGX53_20235	COG1988	membrane-bound metal-dependent
EGX53_20245	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX53_20255	COG2197	response regulator
EGX53_20260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX53_20260	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX53_20265	COG3062	negative regulation of establishment of protein localization
EGX53_20275	COG3043	anaerobic respiration
EGX53_20280	COG3005	denitrification pathway
EGX53_20325	COG3111	PFAM Bacterial OB fold (BOF) protein
EGX53_20335	COG2837	iron assimilation
EGX53_20340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX53_20350	COG4886	Leucine-rich repeat (LRR) protein
EGX53_20360	COG2731	YhcH YjgK YiaL family protein
EGX53_20370	COG1737	Transcriptional regulator
EGX53_20380	COG4150	thiosulfate binding
EGX53_20385	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGX53_20390	COG4208	sulfate ABC transporter
EGX53_20400	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGX53_20410	COG0745	RESPONSE REGULATOR receiver
EGX53_20415	COG3850	Histidine kinase
EGX53_20415	COG5002	protein histidine kinase activity
EGX53_20425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
EGX53_20430	COG0006	proline dipeptidase activity
EGX53_20440	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX53_20455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX53_20460	COG0745	RESPONSE REGULATOR receiver
EGX53_20465	COG2205	protein histidine kinase activity
EGX53_20470	COG2190	(PTS) system
EGX53_20480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX53_20485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGX53_20490	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
EGX53_20505	COG3530	Putative quorum-sensing-regulated virulence factor
EGX53_20575	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
EGX53_20590	COG0667	Aldo Keto reductase
EGX53_20615	COG0436	Aminotransferase
EGX53_20620	COG3038	cytochrome b561
EGX53_20650	COG3381	protein complex oligomerization
EGX53_20665	COG3302	dmso reductase anchor subunit
EGX53_20670	COG0437	4 iron, 4 sulfur cluster binding
EGX53_20675	COG0243	molybdopterin cofactor binding
EGX53_20710	COG2951	lytic endotransglycosylase activity
EGX53_20770	COG3121	Chaperone
EGX53_20775	COG3188	usher protein
EGX53_20820	COG3501	Rhs element vgr protein
EGX53_20850	COG2824	Alkylphosphonate utilization operon protein PhnA
EGX53_20865	COG1704	LemA family
EGX53_20885	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX53_20890	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX53_20895	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
EGX53_20905	COG1138	Cytochrome C-type biogenesis protein
EGX53_20910	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
EGX53_20915	COG4235	cytochrome complex assembly
EGX53_20915	COG3088	subunit of a heme lyase
EGX53_20920	COG3088	subunit of a heme lyase
EGX53_20920	COG4235	cytochrome complex assembly
EGX53_20935	COG3691	Protein conserved in bacteria
EGX53_20950	COG2062	phosphohistidine phosphatase, SixA
EGX53_20960	COG2890	protein-(glutamine-N5) methyltransferase activity
EGX53_20975	COG0730	response to heat
EGX53_20980	COG3101	peptidyl-lysine hydroxylation
EGX53_20995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX53_21000	COG1794	racemase activity, acting on amino acids and derivatives
EGX53_21015	COG0697	spore germination
EGX53_21030	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
EGX53_21040	COG0586	Pfam SNARE associated Golgi protein
EGX53_21050	COG0285	dihydrofolate synthase activity
EGX53_21055	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
EGX53_21060	COG1286	toxin biosynthetic process
EGX53_21065	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EGX53_21070	COG0163	prenyltransferase activity
EGX53_21075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX53_21080	COG4215	(ABC) transporter
EGX53_21085	COG4160	amino acid transport
EGX53_21090	COG4598	ABC transporter
EGX53_21095	COG1090	epimerase
EGX53_21110	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
EGX53_21115	COG3037	sugar-specific permease SgaT UlaA
EGX53_21130	COG1609	Transcriptional regulator
EGX53_21135	COG0280	phosphate acetyltransferase
EGX53_21135	COG0857	belongs to the CobB CobQ family
EGX53_21155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX53_21160	COG0471	metal ion transport
EGX53_21160	COG0490	domain, Protein
EGX53_21175	COG0436	Aminotransferase
EGX53_21180	COG0583	DNA-binding transcription factor activity
EGX53_21190	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX53_21200	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
EGX53_21210	COG1034	ATP synthesis coupled electron transport
EGX53_21225	COG0839	Belongs to the complex I subunit 6 family
EGX53_21235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX53_21240	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX53_21255	COG2731	YhcH YjgK YiaL family protein
EGX53_21260	COG3265	gluconokinase activity
EGX53_21265	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_21280	COG1609	Transcriptional regulator
EGX53_21285	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
EGX53_21300	COG0129	dihydroxy-acid dehydratase activity
EGX53_21315	COG4575	ribosome binding
EGX53_21330	COG1169	isochorismate synthase
EGX53_21345	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
EGX53_21360	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX53_21390	COG1126	abc transporter atp-binding protein
EGX53_21395	COG0765	amino acid transport
EGX53_21400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX53_21435	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EGX53_21455	COG1063	alcohol dehydrogenase
EGX53_21460	COG1879	ABC-type sugar transport system periplasmic component
EGX53_21465	COG1129	ABC transporter
EGX53_21470	COG1172	Belongs to the binding-protein-dependent transport system permease family
EGX53_21475	COG1609	Transcriptional regulator
EGX53_21480	COG0583	DNA-binding transcription factor activity
EGX53_21485	COG0473	3-isopropylmalate dehydrogenase activity
EGX53_21495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX53_21500	COG4638	Rieske (2fe-2S)
EGX53_21505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX53_21510	COG2831	hemolysin activation secretion protein
EGX53_21535	COG3210	domain, Protein
EGX53_21545	COG3328	transposase activity
EGX53_21555	COG1476	TRANSCRIPTIONal
EGX53_21570	COG3842	ATPase activity
EGX53_21580	COG1609	Transcriptional regulator
EGX53_21595	COG0395	ABC-type sugar transport system, permease component
EGX53_21600	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
EGX53_21625	COG0668	transmembrane transport
EGX53_21630	COG1518	maintenance of DNA repeat elements
EGX53_21635	COG1203	CRISPR-associated helicase, Cas3
EGX53_21660	COG0667	Aldo Keto reductase
EGX53_21670	COG0477	Major facilitator Superfamily
EGX53_21680	COG0583	DNA-binding transcription factor activity
EGX53_21685	COG2771	luxR family
EGX53_21690	COG3916	Acyl-homoserine-lactone synthase
EGX53_21720	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
EGX53_21725	COG2943	transferase activity, transferring hexosyl groups
EGX53_21730	COG5645	(Lipo)protein
EGX53_21735	COG3104	oligopeptide transport
EGX53_21740	COG1560	Kdo2-lipid A biosynthetic process
EGX53_21760	COG0628	permease
EGX53_21800	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EGX53_21810	COG1530	ribonuclease E activity
EGX53_21820	COG0564	pseudouridine synthase activity
EGX53_21825	COG1943	Transposase
EGX53_21835	COG1399	metal-binding, possibly nucleic acid-binding protein
EGX53_21840	COG0333	Belongs to the bacterial ribosomal protein bL32 family
EGX53_21860	COG1028	Short-chain dehydrogenase reductase Sdr
EGX53_21870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EGX53_21875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX53_21880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGX53_21890	COG0470	DNA polymerase III
EGX53_21895	COG0084	hydrolase, TatD family'
EGX53_21900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
EGX53_21900	COG1263	PTS System
EGX53_21905	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
EGX53_21910	COG0537	adenosine 5'-monophosphoramidase activity
EGX53_21915	COG5633	Lipoprotein
EGX53_21940	COG1252	NADH dehydrogenase
EGX53_21955	COG3134	Outer membrane lipoprotein
EGX53_21960	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGX53_21965	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGX53_21975	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGX53_21990	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EGX53_22000	COG2850	peptidyl-arginine hydroxylation
EGX53_22010	COG0745	RESPONSE REGULATOR receiver
EGX53_22020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily