locus-tag	class	description
DN756_00010	COG0592	DNA-directed DNA polymerase activity
DN756_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DN756_00025	COG0187	DNA topoisomerase II activity
DN756_00030	COG0561	phosphatase activity
DN756_00040	COG2423	ornithine cyclodeaminase activity
DN756_00045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DN756_00050	COG0823	Involved in the tonB-independent uptake of proteins
DN756_00055	COG5645	(Lipo)protein
DN756_00075	COG3977	Valine--pyruvate aminotransferase
DN756_00095	COG0366	Alpha amylase catalytic
DN756_00115	COG2885	chlorophyll binding
DN756_00125	COG2818	Glycosylase
DN756_00155	COG2213	PTS system mannitol-specific
DN756_00155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN756_00165	COG3722	fumarate hydratase activity
DN756_00190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DN756_00200	COG0243	molybdopterin cofactor binding
DN756_00200	COG3383	formate dehydrogenase (NAD+) activity
DN756_00205	COG3383	formate dehydrogenase (NAD+) activity
DN756_00205	COG0243	molybdopterin cofactor binding
DN756_00210	COG0437	4 iron, 4 sulfur cluster binding
DN756_00215	COG2864	formate dehydrogenase
DN756_00230	COG3276	selenocysteine insertion sequence binding
DN756_00275	COG3274	enterobacterial common antigen metabolic process
DN756_00285	COG3188	usher protein
DN756_00290	COG3121	Chaperone
DN756_00300	COG1070	Carbohydrate kinase
DN756_00310	COG4213	ABC transporter substrate-binding protein
DN756_00320	COG4214	carbohydrate transport
DN756_00325	COG2207	Transcriptional regulator
DN756_00325	COG1609	Transcriptional regulator
DN756_00330	COG0582	viral genome integration into host DNA
DN756_00360	COG4604	ABC transporter, ATP-binding protein
DN756_00365	COG4605	iron ion homeostasis
DN756_00375	COG4607	ABC-type enterochelin transport system periplasmic component
DN756_00390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DN756_00420	COG2194	sulfuric ester hydrolase activity
DN756_00425	COG2197	response regulator
DN756_00430	COG3851	Histidine kinase
DN756_00435	COG2271	Major facilitator Superfamily
DN756_00450	COG2831	hemolysin activation secretion protein
DN756_00460	COG0747	negative chemotaxis
DN756_00465	COG0601	transmembrane transport
DN756_00470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN756_00475	COG0444	Belongs to the ABC transporter superfamily
DN756_00480	COG4608	Belongs to the ABC transporter superfamily
DN756_00490	COG2199	diguanylate cyclase activity
DN756_00490	COG2200	EAL domain
DN756_00495	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DN756_00515	COG0612	Peptidase, M16
DN756_00520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN756_00525	COG1942	4-Oxalocrotonate Tautomerase
DN756_00530	COG2200	EAL domain
DN756_00535	COG2982	Protein involved in outer membrane biogenesis
DN756_00540	COG2134	cdp-diacylglycerol pyrophosphatase
DN756_00545	COG1295	ribonuclease BN
DN756_00570	COG1929	Belongs to the glycerate kinase type-1 family
DN756_00575	COG2610	gluconate transmembrane transporter activity
DN756_00585	COG3835	regulator
DN756_00590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN756_00595	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DN756_00600	COG0339	signal peptide processing
DN756_00620	COG0589	response to stress
DN756_00630	COG0306	phosphate transporter
DN756_00635	COG2081	HI0933 family
DN756_00650	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_00655	COG1879	ABC-type sugar transport system periplasmic component
DN756_00665	COG0191	fructose-bisphosphate aldolase activity
DN756_00675	COG0745	RESPONSE REGULATOR receiver
DN756_00690	COG1741	Belongs to the pirin family
DN756_00695	COG1609	Transcriptional regulator
DN756_00700	COG2610	gluconate transmembrane transporter activity
DN756_00705	COG3265	gluconokinase activity
DN756_00725	COG2095	MarC family integral membrane protein
DN756_00730	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DN756_00755	COG3275	phosphorelay sensor kinase activity
DN756_00780	COG0058	SHG alpha-glucan phosphorylase activity
DN756_00785	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DN756_00815	COG1349	DNA-binding transcription factor activity
DN756_00835	COG0058	SHG alpha-glucan phosphorylase activity
DN756_00840	COG1640	4-alpha-glucanotransferase
DN756_00875	COG1918	ferrous iron import across plasma membrane
DN756_00880	COG2183	response to ionizing radiation
DN756_00885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DN756_00890	COG0745	RESPONSE REGULATOR receiver
DN756_00910	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DN756_00915	COG1011	Hydrolase
DN756_00925	COG0494	nUDIX hydrolase
DN756_01010	COG3179	chitinase
DN756_01025	COG4382	Mu-like prophage protein Gp16
DN756_01100	COG3423	Transcriptional regulator
DN756_01110	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
DN756_01140	COG4796	Type ii and iii secretion system protein
DN756_01170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DN756_01175	COG0546	phosphoglycolate phosphatase activity
DN756_01180	COG0180	Tryptophanyl-tRNA synthetase
DN756_01195	COG2146	nitrite reductase [NAD(P)H] activity
DN756_01200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN756_01205	COG0402	S-adenosylhomocysteine deaminase activity
DN756_01225	COG1486	melibiose metabolic process
DN756_01230	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DN756_01235	COG0433	COG0433 Predicted ATPase
DN756_01250	COG1289	transmembrane transporter activity
DN756_01260	COG1765	OsmC-like protein
DN756_01265	COG3157	Type VI secretion system effector, Hcp
DN756_01280	COG3954	Phosphoribulokinase
DN756_01290	COG0429	hydrolase of the alpha beta-hydrolase fold
DN756_01300	COG4521	taurine ABC transporter
DN756_01310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN756_01315	COG2175	clavaminate synthase activity
DN756_01325	COG1216	Glycosyl transferase, family 2
DN756_01330	COG0488	(ABC) transporter
DN756_01335	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN756_01345	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DN756_01350	COG1047	Peptidyl-prolyl cis-trans
DN756_01365	COG0545	Peptidyl-prolyl cis-trans isomerase
DN756_01370	COG2964	Protein conserved in bacteria
DN756_01390	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DN756_01395	COG0049	tRNA binding
DN756_01415	COG1943	Transposase
DN756_01435	COG0051	transcription antitermination factor activity, RNA binding
DN756_01460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DN756_01470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DN756_01475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DN756_01485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DN756_01490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DN756_01530	COG1841	ribosomal large subunit assembly
DN756_01540	COG0201	protein transport
DN756_01545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DN756_01560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DN756_01575	COG0789	Transcriptional regulator
DN756_01580	COG3036	rescue of stalled ribosome
DN756_01590	COG0569	domain protein
DN756_01610	COG0758	DNA mediated transformation
DN756_01620	COG0551	DNA topoisomerase type I activity
DN756_01635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DN756_01715	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DN756_01720	COG0250	Participates in transcription elongation, termination and antitermination
DN756_01775	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DN756_01785	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DN756_01810	COG1515	deoxyribonuclease V activity
DN756_01815	COG3068	Protein conserved in bacteria
DN756_01830	COG0151	Belongs to the GarS family
DN756_01890	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DN756_01895	COG2224	Isocitrate lyase
DN756_01905	COG1414	Transcriptional regulator
DN756_01920	COG0527	aspartate kinase activity
DN756_01935	COG3833	ABC-type maltose transport systems, permease component
DN756_01940	COG1175	transmembrane transport
DN756_02060	COG3501	Rhs element vgr protein
DN756_02120	COG3501	Rhs element vgr protein
DN756_02135	COG0673	inositol 2-dehydrogenase activity
DN756_02140	COG2207	Transcriptional regulator
DN756_02145	COG1869	D-ribose catabolic process
DN756_02150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN756_02165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN756_02175	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN756_02190	COG3077	Addiction module antitoxin, RelB DinJ family
DN756_02195	COG2252	PERMEase
DN756_02200	COG3328	transposase activity
DN756_02205	COG0025	NhaP-type Na H and K H
DN756_02215	COG1560	Kdo2-lipid A biosynthetic process
DN756_02225	COG1129	ABC transporter
DN756_02230	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_02240	COG1069	ribulokinase activity
DN756_02250	COG0625	glutathione transferase activity
DN756_02265	COG1278	Cold shock
DN756_02270	COG1278	Cold shock
DN756_02275	COG1278	Cold shock
DN756_02285	COG3133	Outer membrane lipoprotein
DN756_02290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN756_02300	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DN756_02330	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DN756_02335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN756_02345	COG4145	pantothenate transmembrane transporter activity
DN756_02350	COG3924	membrane
DN756_02355	COG0439	Biotin carboxylase
DN756_02360	COG0511	ligase activity, forming carbon-carbon bonds
DN756_02380	COG0604	alcohol dehydrogenase
DN756_02385	COG2200	EAL domain
DN756_02385	COG2199	diguanylate cyclase activity
DN756_02390	COG1077	Cell shape determining protein MreB Mrl
DN756_02395	COG1792	Involved in formation and maintenance of cell shape
DN756_02400	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DN756_02410	COG1530	ribonuclease E activity
DN756_02415	COG3164	Protein of unknown function
DN756_02420	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN756_02425	COG0312	modulator of DNA gyrase
DN756_02470	COG0583	DNA-binding transcription factor activity
DN756_02500	COG2732	(Barnase) inhibitor
DN756_02510	COG0312	modulator of DNA gyrase
DN756_02520	COG3783	Cytochrome b(562)
DN756_02525	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DN756_02530	COG0366	Alpha amylase catalytic
DN756_02535	COG1263	PTS System
DN756_02535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN756_02540	COG1609	Transcriptional regulator
DN756_02570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN756_02585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN756_02595	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DN756_02600	COG1137	ATPase activity
DN756_02605	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DN756_02610	COG3117	lipopolysaccharide transmembrane transporter activity
DN756_02615	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DN756_02620	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DN756_02620	COG0517	IMP dehydrogenase activity
DN756_02625	COG0530	calcium, potassium:sodium antiporter activity
DN756_02630	COG1127	ABC transporter
DN756_02635	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DN756_02640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DN756_02645	COG2854	intermembrane phospholipid transfer
DN756_02650	COG3113	response to antibiotic
DN756_02655	COG5007	Belongs to the BolA IbaG family
DN756_02665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN756_02670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN756_02675	COG3105	Protein conserved in bacteria
DN756_02680	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DN756_02700	COG0625	glutathione transferase activity
DN756_02705	COG2969	positive regulation of protein catabolic process
DN756_02715	COG0493	'glutamate synthase
DN756_02720	COG0067	glutamate synthase
DN756_02720	COG0069	glutamate synthase activity
DN756_02720	COG0070	glutamate synthase
DN756_02725	COG1242	4 iron, 4 sulfur cluster binding
DN756_02735	COG0784	Response regulator, receiver
DN756_02735	COG5002	protein histidine kinase activity
DN756_02735	COG2198	Histidine kinase
DN756_02745	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DN756_02755	COG2823	Periplasmic or secreted lipoprotein
DN756_02780	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
DN756_02790	COG1741	Belongs to the pirin family
DN756_02795	COG0583	DNA-binding transcription factor activity
DN756_02805	COG2259	Doxx family
DN756_02815	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
DN756_02820	COG4575	ribosome binding
DN756_02840	COG0586	Pfam SNARE associated Golgi protein
DN756_02855	COG2271	Major facilitator Superfamily
DN756_02865	COG0246	Mannitol dehydrogenase
DN756_02870	COG2721	sulfolactate sulfo-lyase activity
DN756_02885	COG0673	inositol 2-dehydrogenase activity
DN756_02890	COG1451	nucleotide metabolic process
DN756_02905	COG0446	pyridine nucleotide-disulphide oxidoreductase
DN756_02905	COG1902	pentaerythritol trinitrate reductase activity
DN756_02910	COG3247	response to pH
DN756_02945	COG4245	von Willebrand factor, type A
DN756_02950	COG2831	hemolysin activation secretion protein
DN756_02980	COG3210	domain, Protein
DN756_02990	COG3210	domain, Protein
DN756_02995	COG3210	domain, Protein
DN756_03010	COG3210	domain, Protein
DN756_03015	COG3210	domain, Protein
DN756_03035	COG3842	ATPase activity
DN756_03040	COG3459	Glycosyltransferase 36 associated
DN756_03045	COG1609	Transcriptional regulator
DN756_03050	COG1653	transport
DN756_03060	COG0395	ABC-type sugar transport system, permease component
DN756_03080	COG1289	transmembrane transporter activity
DN756_03125	COG0251	oxidation-reduction process
DN756_03165	COG3157	Type VI secretion system effector, Hcp
DN756_03200	COG3561	AntA/AntB antirepressor
DN756_03300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DN756_03305	COG0358	DNA primase activity
DN756_03325	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DN756_03340	COG4991	sh3 domain protein
DN756_03345	COG3025	triphosphatase activity
DN756_03360	COG0531	amino acid
DN756_03380	COG3384	dioxygenase
DN756_03385	COG0754	glutathionylspermidine amidase activity
DN756_03400	COG1538	Outer membrane efflux protein
DN756_03405	COG0494	nUDIX hydrolase
DN756_03410	COG3151	Protein conserved in bacteria
DN756_03415	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DN756_03420	COG3150	esterase
DN756_03425	COG0187	DNA topoisomerase II activity
DN756_03430	COG0583	DNA-binding transcription factor activity
DN756_03435	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN756_03445	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DN756_03450	COG0204	Acyl-transferase
DN756_03460	COG2132	Multicopper oxidase
DN756_03475	COG0656	L-ascorbic acid biosynthetic process
DN756_03485	COG1979	alcohol dehydrogenase
DN756_03490	COG2207	Transcriptional regulator
DN756_03495	COG0586	Pfam SNARE associated Golgi protein
DN756_03500	COG0626	cystathionine gamma-synthase activity
DN756_03505	COG0811	peptide transport
DN756_03510	COG0848	biopolymer transport protein
DN756_03565	COG4964	Belongs to the GSP D family
DN756_03595	COG3397	chitin binding
DN756_03600	COG3469	chitinase activity
DN756_03625	COG4592	Periplasmic binding protein
DN756_03645	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DN756_03650	COG1684	flagellar biosynthetic protein fliR
DN756_03655	COG1987	bacterial-type flagellum assembly
DN756_03675	COG2204	response regulator
DN756_03720	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
DN756_03725	COG1815	bacterial-type flagellum-dependent cell motility
DN756_03730	COG1558	bacterial-type flagellum-dependent cell motility
DN756_03735	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DN756_03805	COG3133	Outer membrane lipoprotein
DN756_03815	COG5001	Diguanylate cyclase
DN756_03815	COG3300	MHYT domain
DN756_03825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN756_03885	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
DN756_03890	COG2195	Cleaves the N-terminal amino acid of tripeptides
DN756_03895	COG4771	TonB-dependent receptor
DN756_03900	COG3433	isochorismatase activity
DN756_03900	COG2226	methyltransferase
DN756_03900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN756_03905	COG2226	methyltransferase
DN756_03905	COG3433	isochorismatase activity
DN756_03905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN756_03935	COG1132	(ABC) transporter
DN756_03950	COG2610	gluconate transmembrane transporter activity
DN756_03960	COG3501	Rhs element vgr protein
DN756_04035	COG0471	metal ion transport
DN756_04040	COG1609	Transcriptional regulator
DN756_04050	COG2211	Major facilitator Superfamily
DN756_04100	COG2771	luxR family
DN756_04105	COG3916	Acyl-homoserine-lactone synthase
DN756_04210	COG1982	Orn Lys Arg decarboxylase major
DN756_04215	COG1879	ABC-type sugar transport system periplasmic component
DN756_04220	COG1129	ABC transporter
DN756_04225	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_04230	COG4774	siderophore transport
DN756_04250	COG1194	a g-specific adenine glycosylase
DN756_04260	COG3171	Protein conserved in bacteria
DN756_04265	COG2066	Belongs to the glutaminase family
DN756_04275	COG1073	alpha beta
DN756_04275	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DN756_04275	COG3064	Membrane
DN756_04280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN756_04285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DN756_04295	COG0762	integral membrane protein
DN756_04300	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DN756_04305	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DN756_04310	COG2805	Type II/IV secretion system protein
DN756_04320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN756_04335	COG0189	ligase activity
DN756_04340	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DN756_04350	COG2356	endonuclease I
DN756_04365	COG1166	arginine decarboxylase activity
DN756_04375	COG1943	Transposase
DN756_04385	COG1943	Transposase
DN756_04390	COG0501	Belongs to the peptidase M48B family
DN756_04395	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DN756_04410	COG0191	fructose-bisphosphate aldolase activity
DN756_04440	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DN756_04445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DN756_04450	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DN756_04475	COG0006	proline dipeptidase activity
DN756_04480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DN756_04485	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DN756_04520	COG5295	Hep Hag repeat protein
DN756_04530	COG1272	protein, Hemolysin III
DN756_04545	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DN756_04555	COG0745	RESPONSE REGULATOR receiver
DN756_04560	COG2205	protein histidine kinase activity
DN756_04565	COG4452	Inner membrane protein CreD
DN756_04570	COG0716	FMN binding
DN756_04575	COG4974	Belongs to the 'phage' integrase family
DN756_04580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DN756_04585	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DN756_04605	COG0582	viral genome integration into host DNA
DN756_04790	COG1695	Transcriptional regulator
DN756_04795	COG0791	NLP P60 protein
DN756_04805	COG1879	ABC-type sugar transport system periplasmic component
DN756_04810	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_04815	COG1129	ABC transporter
DN756_04825	COG2182	Extracellular solute-binding protein
DN756_04830	COG1175	transmembrane transport
DN756_04835	COG3833	ABC-type maltose transport systems, permease component
DN756_04840	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DN756_04845	COG1874	Beta-galactosidase
DN756_04850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN756_04850	COG1263	PTS System
DN756_04870	COG2271	Major facilitator Superfamily
DN756_04890	COG0191	fructose-bisphosphate aldolase activity
DN756_04900	COG3119	arylsulfatase activity
DN756_04905	COG0641	radical SAM
DN756_04915	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_04925	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN756_04930	COG3716	PTS system mannose fructose sorbose family IID component
DN756_04935	COG3715	PTS system
DN756_04940	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN756_04945	COG2222	sugar isomerase
DN756_04955	COG1349	DNA-binding transcription factor activity
DN756_04960	COG3119	arylsulfatase activity
DN756_04990	COG0288	reversible hydration of carbon dioxide
DN756_05040	COG2165	general secretion pathway protein
DN756_05080	COG0840	transmembrane signaling receptor activity
DN756_05100	COG2814	Major facilitator Superfamily
DN756_05105	COG0583	DNA-binding transcription factor activity
DN756_05110	COG0019	diaminopimelate decarboxylase activity
DN756_05115	COG1609	Transcriptional regulator
DN756_05145	COG0667	Aldo Keto reductase
DN756_05210	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DN756_05220	COG1074	ATP-dependent DNA helicase activity
DN756_05225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DN756_05235	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN756_05255	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DN756_05260	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DN756_05265	COG2166	iron-sulfur cluster assembly
DN756_05270	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DN756_05280	COG0583	DNA-binding transcription factor activity
DN756_05285	COG2363	Small membrane protein
DN756_05305	COG1611	Belongs to the LOG family
DN756_05320	COG3098	single-species biofilm formation
DN756_05325	COG0564	pseudouridine synthase activity
DN756_05350	COG0024	Methionine aminopeptidase
DN756_05385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DN756_05390	COG0575	Belongs to the CDS family
DN756_05395	COG0750	zinc metalloprotease
DN756_05405	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
DN756_05425	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DN756_05435	COG0587	DNA-directed DNA polymerase activity
DN756_05445	COG0346	lactoylglutathione lyase activity
DN756_05460	COG4568	rho-dependent transcription termination
DN756_05470	COG4681	YaeQ
DN756_05480	COG3015	lipoprotein NlpE involved in copper resistance
DN756_05490	COG1720	tRNA m6t6A37 methyltransferase activity
DN756_05500	COG1464	Belongs to the NlpA lipoprotein family
DN756_05505	COG2011	ABC-type metal ion transport system permease component
DN756_05515	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DN756_05550	COG0656	L-ascorbic acid biosynthetic process
DN756_05570	COG0741	lytic transglycosylase activity
DN756_05570	COG1388	LysM domain
DN756_05580	COG2226	methyltransferase
DN756_05590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DN756_05600	COG1953	Uracil, thiamine, allantoin
DN756_05610	COG2113	Glycine betaine
DN756_05615	COG4176	ABC-type proline glycine betaine transport system permease component
DN756_05620	COG4175	Glycine betaine
DN756_05625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DN756_05665	COG1278	Cold shock
DN756_05670	COG0747	negative chemotaxis
DN756_05680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN756_05685	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DN756_05690	COG1124	(ABC) transporter
DN756_05720	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DN756_05730	COG4413	Urea transporter
DN756_05735	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DN756_05750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN756_05755	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DN756_05770	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN756_05775	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
DN756_05780	COG1447	Phosphotransferase system cellobiose-specific component IIA
DN756_05785	COG1917	Cupin 2, conserved barrel domain protein
DN756_05785	COG2169	Transcriptional regulator
DN756_05810	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
DN756_05815	COG0033	Phosphoglucomutase
DN756_05830	COG0745	RESPONSE REGULATOR receiver
DN756_05835	COG2205	protein histidine kinase activity
DN756_05875	COG3272	Protein of unknown function (DUF1722)
DN756_05885	COG5212	phosphodiesterase
DN756_05890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DN756_05895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DN756_05900	COG1984	allophanate hydrolase subunit 2
DN756_05945	COG0513	Belongs to the DEAD box helicase family
DN756_05955	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DN756_05965	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
DN756_05970	COG3026	antisigma factor binding
DN756_05975	COG3086	response to oxidative stress
DN756_05990	COG0681	Belongs to the peptidase S26 family
DN756_06010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DN756_06020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DN756_06025	COG1737	Transcriptional regulator
DN756_06035	COG0560	Phosphoserine phosphatase
DN756_06040	COG0590	tRNA wobble adenosine to inosine editing
DN756_06070	COG2205	protein histidine kinase activity
DN756_06075	COG3170	Tfp pilus assembly protein FimV
DN756_06080	COG2204	response regulator
DN756_06085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN756_06085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DN756_06090	COG0347	Belongs to the P(II) protein family
DN756_06095	COG2188	Transcriptional regulator
DN756_06100	COG1017	nitric oxide dioxygenase activity
DN756_06100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN756_06120	COG2814	Major facilitator Superfamily
DN756_06125	COG3711	transcriptional antiterminator
DN756_06130	COG3683	transport system, periplasmic component
DN756_06135	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
DN756_06140	COG0483	inositol monophosphate 1-phosphatase activity
DN756_06155	COG1104	cysteine desulfurase activity
DN756_06160	COG0822	iron-sulfur transferase activity
DN756_06185	COG0633	Ferredoxin
DN756_06190	COG2975	iron-sulfur cluster assembly
DN756_06260	COG2976	Protein conserved in bacteria
DN756_06265	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DN756_06280	COG1645	bacterial-type flagellum-dependent swarming motility
DN756_06290	COG0517	IMP dehydrogenase activity
DN756_06290	COG0516	GMP reductase activity
DN756_06365	COG0351	phosphomethylpyrimidine kinase
DN756_06395	COG3422	double-strand break repair
DN756_06400	COG0745	RESPONSE REGULATOR receiver
DN756_06405	COG2205	protein histidine kinase activity
DN756_06430	COG3842	ATPase activity
DN756_06440	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DN756_06450	COG1176	ABC-type spermidine putrescine transport system, permease component I
DN756_06455	COG1177	transmembrane transport
DN756_06460	COG0443	Heat shock 70 kDa protein
DN756_06465	COG2239	Acts as a magnesium transporter
DN756_06475	COG0248	Ppx GppA phosphatase
DN756_06480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DN756_06490	COG0581	inorganic phosphate transmembrane transporter activity
DN756_06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN756_06510	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DN756_06525	COG2233	PERMEase
DN756_06535	COG1393	Belongs to the ArsC family
DN756_06540	COG4783	chaperone-mediated protein folding
DN756_06545	COG0628	permease
DN756_06560	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DN756_06565	COG2716	regulation of RNA biosynthetic process
DN756_06575	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DN756_06585	COG2321	neutral zinc metallopeptidase
DN756_06605	COG1876	peptidase activity
DN756_06615	COG1393	Belongs to the ArsC family
DN756_06625	COG1840	ABC-type Fe3 transport system, periplasmic component
DN756_06630	COG1175	transmembrane transport
DN756_06635	COG3842	ATPase activity
DN756_06645	COG3119	arylsulfatase activity
DN756_06650	COG0641	radical SAM
DN756_06655	COG1988	membrane-bound metal-dependent
DN756_06665	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN756_06675	COG2197	response regulator
DN756_06680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DN756_06680	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
DN756_06685	COG3062	negative regulation of establishment of protein localization
DN756_06695	COG3043	anaerobic respiration
DN756_06700	COG3005	denitrification pathway
DN756_06745	COG3111	PFAM Bacterial OB fold (BOF) protein
DN756_06755	COG2837	iron assimilation
DN756_06760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN756_06770	COG4886	Leucine-rich repeat (LRR) protein
DN756_06780	COG2731	YhcH YjgK YiaL family protein
DN756_06790	COG1737	Transcriptional regulator
DN756_06800	COG4150	thiosulfate binding
DN756_06805	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DN756_06810	COG4208	sulfate ABC transporter
DN756_06820	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN756_06830	COG0745	RESPONSE REGULATOR receiver
DN756_06835	COG5002	protein histidine kinase activity
DN756_06835	COG3850	Histidine kinase
DN756_06845	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DN756_06850	COG0006	proline dipeptidase activity
DN756_06860	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN756_06875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN756_06880	COG0745	RESPONSE REGULATOR receiver
DN756_06885	COG2205	protein histidine kinase activity
DN756_06890	COG2190	(PTS) system
DN756_06900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN756_06905	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN756_06910	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
DN756_06925	COG3530	Putative quorum-sensing-regulated virulence factor
DN756_06995	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN756_07010	COG0667	Aldo Keto reductase
DN756_07035	COG0436	Aminotransferase
DN756_07040	COG3038	cytochrome b561
DN756_07070	COG3381	protein complex oligomerization
DN756_07080	COG3302	dmso reductase anchor subunit
DN756_07085	COG0437	4 iron, 4 sulfur cluster binding
DN756_07090	COG0243	molybdopterin cofactor binding
DN756_07125	COG2951	lytic endotransglycosylase activity
DN756_07185	COG3121	Chaperone
DN756_07190	COG3188	usher protein
DN756_07235	COG3501	Rhs element vgr protein
DN756_07265	COG2824	Alkylphosphonate utilization operon protein PhnA
DN756_07280	COG1704	LemA family
DN756_07300	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DN756_07305	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DN756_07310	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DN756_07320	COG1138	Cytochrome C-type biogenesis protein
DN756_07325	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DN756_07330	COG4235	cytochrome complex assembly
DN756_07330	COG3088	subunit of a heme lyase
DN756_07335	COG3088	subunit of a heme lyase
DN756_07335	COG4235	cytochrome complex assembly
DN756_07350	COG3691	Protein conserved in bacteria
DN756_07365	COG2062	phosphohistidine phosphatase, SixA
DN756_07375	COG2890	protein-(glutamine-N5) methyltransferase activity
DN756_07390	COG0730	response to heat
DN756_07395	COG3101	peptidyl-lysine hydroxylation
DN756_07410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DN756_07415	COG1794	racemase activity, acting on amino acids and derivatives
DN756_07430	COG0697	spore germination
DN756_07445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
DN756_07455	COG0586	Pfam SNARE associated Golgi protein
DN756_07465	COG0285	dihydrofolate synthase activity
DN756_07470	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
DN756_07475	COG1286	toxin biosynthetic process
DN756_07480	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DN756_07485	COG0163	prenyltransferase activity
DN756_07490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN756_07495	COG4215	(ABC) transporter
DN756_07500	COG4160	amino acid transport
DN756_07505	COG4598	ABC transporter
DN756_07510	COG1090	epimerase
DN756_07520	COG0622	Phosphoesterase
DN756_07525	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
DN756_07530	COG3037	sugar-specific permease SgaT UlaA
DN756_07545	COG1609	Transcriptional regulator
DN756_07550	COG0280	phosphate acetyltransferase
DN756_07550	COG0857	belongs to the CobB CobQ family
DN756_07575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN756_07580	COG0471	metal ion transport
DN756_07580	COG0490	domain, Protein
DN756_07595	COG0436	Aminotransferase
DN756_07600	COG0583	DNA-binding transcription factor activity
DN756_07610	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DN756_07620	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DN756_07630	COG1034	ATP synthesis coupled electron transport
DN756_07645	COG0839	Belongs to the complex I subunit 6 family
DN756_07655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DN756_07660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DN756_07675	COG2731	YhcH YjgK YiaL family protein
DN756_07680	COG3265	gluconokinase activity
DN756_07685	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_07700	COG1609	Transcriptional regulator
DN756_07705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DN756_07720	COG0129	dihydroxy-acid dehydratase activity
DN756_07735	COG4575	ribosome binding
DN756_07750	COG1169	isochorismate synthase
DN756_07765	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DN756_07780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DN756_07810	COG1126	abc transporter atp-binding protein
DN756_07815	COG0765	amino acid transport
DN756_07820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN756_07855	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DN756_07875	COG1063	alcohol dehydrogenase
DN756_07880	COG1879	ABC-type sugar transport system periplasmic component
DN756_07885	COG1129	ABC transporter
DN756_07890	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_07895	COG1609	Transcriptional regulator
DN756_07900	COG0583	DNA-binding transcription factor activity
DN756_07905	COG0473	3-isopropylmalate dehydrogenase activity
DN756_07915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN756_07920	COG4638	Rieske (2fe-2S)
DN756_07925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN756_07930	COG2831	hemolysin activation secretion protein
DN756_07955	COG3210	domain, Protein
DN756_07965	COG3328	transposase activity
DN756_07975	COG1476	TRANSCRIPTIONal
DN756_07990	COG3842	ATPase activity
DN756_08000	COG1609	Transcriptional regulator
DN756_08015	COG0395	ABC-type sugar transport system, permease component
DN756_08020	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
DN756_08045	COG0668	transmembrane transport
DN756_08050	COG1518	maintenance of DNA repeat elements
DN756_08055	COG1203	CRISPR-associated helicase, Cas3
DN756_08080	COG0667	Aldo Keto reductase
DN756_08090	COG0477	Major facilitator Superfamily
DN756_08100	COG0583	DNA-binding transcription factor activity
DN756_08105	COG2771	luxR family
DN756_08110	COG3916	Acyl-homoserine-lactone synthase
DN756_08140	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
DN756_08145	COG2943	transferase activity, transferring hexosyl groups
DN756_08150	COG5645	(Lipo)protein
DN756_08155	COG3104	oligopeptide transport
DN756_08160	COG1560	Kdo2-lipid A biosynthetic process
DN756_08180	COG0628	permease
DN756_08220	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DN756_08230	COG1530	ribonuclease E activity
DN756_08240	COG0564	pseudouridine synthase activity
DN756_08245	COG1943	Transposase
DN756_08255	COG1399	metal-binding, possibly nucleic acid-binding protein
DN756_08260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DN756_08280	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_08290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DN756_08295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN756_08300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DN756_08310	COG0470	DNA polymerase III
DN756_08315	COG0084	hydrolase, TatD family'
DN756_08320	COG1263	PTS System
DN756_08320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN756_08325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DN756_08330	COG0537	adenosine 5'-monophosphoramidase activity
DN756_08335	COG5633	Lipoprotein
DN756_08360	COG1252	NADH dehydrogenase
DN756_08375	COG3134	Outer membrane lipoprotein
DN756_08380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DN756_08385	COG4591	ABC-type transport system involved in lipoprotein release permease component
DN756_08395	COG4591	ABC-type transport system involved in lipoprotein release permease component
DN756_08410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DN756_08420	COG2850	peptidyl-arginine hydroxylation
DN756_08430	COG0745	RESPONSE REGULATOR receiver
DN756_08440	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DN756_08460	COG1187	pseudouridine synthase activity
DN756_08465	COG0538	isocitrate dehydrogenase activity
DN756_08480	COG0840	transmembrane signaling receptor activity
DN756_08485	COG0702	epimerase
DN756_08490	COG1733	regulation of RNA biosynthetic process
DN756_08510	COG1522	sequence-specific DNA binding
DN756_08520	COG3321	synthase
DN756_08520	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_08520	COG0604	alcohol dehydrogenase
DN756_08530	COG1278	Cold shock
DN756_08540	COG0840	transmembrane signaling receptor activity
DN756_08545	COG1285	pathogenesis
DN756_08570	COG1360	Flagellar Motor Protein
DN756_08575	COG0643	Histidine kinase
DN756_08575	COG2198	Histidine kinase
DN756_08580	COG0835	chemotaxis
DN756_08595	COG0840	transmembrane signaling receptor activity
DN756_08605	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DN756_08615	COG0745	RESPONSE REGULATOR receiver
DN756_08620	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DN756_08630	COG3023	N-Acetylmuramoyl-L-alanine amidase
DN756_08645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN756_08690	COG3121	Chaperone
DN756_08710	COG3008	intermembrane lipid transfer
DN756_08715	COG2995	paraquat-inducible protein a
DN756_08720	COG1956	GAF domain-containing protein
DN756_08730	COG0793	Belongs to the peptidase S41A family
DN756_08745	COG3539	Fimbrial protein
DN756_08750	COG3121	Chaperone
DN756_08765	COG3121	Chaperone
DN756_08770	COG2814	Major facilitator Superfamily
DN756_08775	COG0823	Involved in the tonB-independent uptake of proteins
DN756_08785	COG3023	N-Acetylmuramoyl-L-alanine amidase
DN756_08795	COG1988	membrane-bound metal-dependent
DN756_08800	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DN756_08805	COG1653	transport
DN756_08810	COG3842	ATPase activity
DN756_08815	COG0395	ABC-type sugar transport system, permease component
DN756_08820	COG1175	transmembrane transport
DN756_08830	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_08840	COG1917	Cupin 2, conserved barrel domain protein
DN756_08850	COG3328	transposase activity
DN756_08860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN756_08880	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DN756_08885	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DN756_08890	COG1121	(ABC) transporter
DN756_08895	COG0803	Belongs to the bacterial solute-binding protein 9 family
DN756_08920	COG4249	Peptidase C14 caspase catalytic subunit p20
DN756_08955	COG0776	regulation of translation
DN756_08970	COG0386	Belongs to the glutathione peroxidase family
DN756_08975	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
DN756_09020	COG0791	NLP P60 protein
DN756_09045	COG0574	Belongs to the PEP-utilizing enzyme family
DN756_09045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DN756_09055	COG0628	permease
DN756_09060	COG0277	FAD linked oxidase domain protein
DN756_09060	COG0247	lactate metabolic process
DN756_09065	COG2050	protein possibly involved in aromatic compounds catabolism
DN756_09075	COG0316	Belongs to the HesB IscA family
DN756_09080	COG0719	Fe-S assembly protein
DN756_09085	COG0396	ATPase activity
DN756_09090	COG0719	Fe-S assembly protein
DN756_09105	COG1376	ErfK ybiS ycfS ynhG family protein
DN756_09105	COG1388	LysM domain
DN756_09110	COG4238	major outer membrane lipoprotein
DN756_09145	COG0307	riboflavin synthase, alpha
DN756_09150	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DN756_09155	COG2814	Major facilitator Superfamily
DN756_09160	COG0583	DNA-binding transcription factor activity
DN756_09175	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DN756_09180	COG0791	NLP P60 protein
DN756_09190	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DN756_09205	COG0346	lactoylglutathione lyase activity
DN756_09215	COG1902	pentaerythritol trinitrate reductase activity
DN756_09220	COG1309	transcriptional regulator
DN756_09230	COG3133	Outer membrane lipoprotein
DN756_09240	COG3895	Periplasmic Protein
DN756_09260	COG0625	glutathione transferase activity
DN756_09275	COG3104	oligopeptide transport
DN756_09280	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DN756_09280	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DN756_09285	COG4172	Belongs to the ABC transporter superfamily
DN756_09295	COG4171	peptide transport system, permease
DN756_09300	COG4168	peptide transport system, permease
DN756_09305	COG4166	transmembrane transport
DN756_09315	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
DN756_09320	COG1842	Phage shock protein A
DN756_09330	COG1983	PspC domain protein
DN756_09340	COG3106	COG3106 Predicted ATPase
DN756_09365	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
DN756_09370	COG4948	Mandelate Racemase Muconate Lactonizing
DN756_09375	COG2866	Carboxypeptidase
DN756_09380	COG4166	transmembrane transport
DN756_09405	COG2755	lipolytic protein G-D-S-L family
DN756_09405	COG0657	acetylesterase activity
DN756_09415	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DN756_09415	COG0674	pyruvate-flavodoxin oxidoreductase activity
DN756_09415	COG1013	pyruvate-flavodoxin oxidoreductase activity
DN756_09415	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DN756_09425	COG1285	pathogenesis
DN756_09430	COG3042	response to heat
DN756_09435	COG3187	Heat shock protein
DN756_09440	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DN756_09445	COG2911	Protein conserved in bacteria
DN756_09455	COG3784	Protein of unknown function (DUF1318)
DN756_09460	COG0246	Mannitol dehydrogenase
DN756_09465	COG2390	Transcriptional regulator
DN756_09475	COG1643	Atp-dependent helicase
DN756_09490	COG3591	Belongs to the peptidase S1B family
DN756_09505	COG3038	cytochrome b561
DN756_09530	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DN756_09535	COG2205	protein histidine kinase activity
DN756_09540	COG0745	RESPONSE REGULATOR receiver
DN756_09550	COG0531	amino acid
DN756_09565	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DN756_09570	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DN756_09575	COG0589	response to stress
DN756_09580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN756_09585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DN756_09600	COG1011	Hydrolase
DN756_09605	COG0440	acetolactate synthase activity
DN756_09610	COG0028	Belongs to the TPP enzyme family
DN756_09640	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DN756_09645	COG1116	anion transmembrane transporter activity
DN756_09650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN756_09655	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN756_09665	COG1129	ABC transporter
DN756_09670	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_09675	COG1879	ABC-type sugar transport system periplasmic component
DN756_09685	COG1609	Transcriptional regulator
DN756_09690	COG1757	Na H antiporter
DN756_09695	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DN756_09725	COG1012	belongs to the aldehyde dehydrogenase family
DN756_09730	COG3284	Transcriptional regulator
DN756_09735	COG4221	oxidoreductase activity
DN756_09755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DN756_09760	COG1940	carbohydrate kinase activity
DN756_09765	COG0583	DNA-binding transcription factor activity
DN756_09770	COG2814	Major facilitator Superfamily
DN756_09780	COG0114	fumarate hydratase activity
DN756_09790	COG5339	Protein conserved in bacteria
DN756_09815	COG0385	Bile acid
DN756_09820	COG0673	inositol 2-dehydrogenase activity
DN756_09830	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_09840	COG1879	ABC-type sugar transport system periplasmic component
DN756_09855	COG2274	protein secretion by the type I secretion system
DN756_09865	COG2274	protein secretion by the type I secretion system
DN756_09890	COG3708	Transcriptional regulator
DN756_09890	COG2207	Transcriptional regulator
DN756_09900	COG4659	FMN binding
DN756_09910	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DN756_09915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN756_09920	COG2271	Major facilitator Superfamily
DN756_09930	COG1966	Carbon starvation protein
DN756_09935	COG2879	small protein
DN756_09940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DN756_09960	COG0023	Translation Initiation Factor
DN756_09975	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DN756_09980	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
DN756_09985	COG0671	phosphoesterase, PA-phosphatase related
DN756_09990	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DN756_09995	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DN756_10010	COG0583	DNA-binding transcription factor activity
DN756_10015	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DN756_10030	COG0616	signal peptide processing
DN756_10035	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_10045	COG1187	pseudouridine synthase activity
DN756_10050	COG0009	L-threonylcarbamoyladenylate synthase
DN756_10075	COG0512	Glutamine amidotransferase of anthranilate synthase
DN756_10085	COG0135	phosphoribosylanthranilate isomerase activity
DN756_10085	COG0134	indole-3-glycerol-phosphate synthase activity
DN756_10105	COG3047	cAMP biosynthetic process
DN756_10135	COG1607	acyl-coa hydrolase
DN756_10140	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
DN756_10145	COG2350	Protein conserved in bacteria
DN756_10185	COG4608	Belongs to the ABC transporter superfamily
DN756_10190	COG0444	Belongs to the ABC transporter superfamily
DN756_10195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN756_10200	COG0601	transmembrane transport
DN756_10210	COG2095	MarC family integral membrane protein
DN756_10220	COG1454	alcohol dehydrogenase
DN756_10220	COG1012	belongs to the aldehyde dehydrogenase family
DN756_10230	COG1435	thymidine kinase activity
DN756_10240	COG1943	Transposase
DN756_10250	COG0745	RESPONSE REGULATOR receiver
DN756_10260	COG0788	formyltetrahydrofolate deformylase activity
DN756_10285	COG0583	DNA-binding transcription factor activity
DN756_10290	COG0708	Exodeoxyribonuclease III
DN756_10295	COG0494	nUDIX hydrolase
DN756_10305	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DN756_10315	COG0778	Nitroreductase
DN756_10320	COG0616	signal peptide processing
DN756_10325	COG0252	asparaginase activity
DN756_10330	COG1335	isochorismatase
DN756_10335	COG3139	Protein of unknown function (DUF1315)
DN756_10355	COG3713	MltA-interacting MipA family protein
DN756_10365	COG2766	serine protein kinase
DN756_10380	COG0583	DNA-binding transcription factor activity
DN756_10390	COG2814	Major facilitator Superfamily
DN756_10400	COG2719	SpoVR family
DN756_10435	COG1104	cysteine desulfurase activity
DN756_10450	COG0179	Fumarylacetoacetate (FAA) hydrolase
DN756_10455	COG2951	lytic endotransglycosylase activity
DN756_10475	COG2894	cell division
DN756_10480	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DN756_10485	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
DN756_10490	COG0318	PFAM AMP-dependent synthetase and ligase
DN756_10500	COG3065	identical protein binding
DN756_10510	COG1199	ATP-dependent helicase activity
DN756_10515	COG0251	oxidation-reduction process
DN756_10530	COG0800	Aldolase
DN756_10540	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DN756_10545	COG1737	Transcriptional regulator
DN756_10550	COG0469	pyruvate kinase activity
DN756_10560	COG1560	Kdo2-lipid A biosynthetic process
DN756_10565	COG0739	heme binding
DN756_10570	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
DN756_10580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DN756_10610	COG0494	nUDIX hydrolase
DN756_10620	COG1801	Protein of unknown function DUF72
DN756_10625	COG3788	relative of glutathione S-transferase, MAPEG superfamily
DN756_10645	COG3102	Protein conserved in bacteria
DN756_10665	COG0728	peptidoglycan biosynthetic process
DN756_10670	COG0673	inositol 2-dehydrogenase activity
DN756_10680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN756_10695	COG3381	protein complex oligomerization
DN756_10710	COG1940	carbohydrate kinase activity
DN756_10715	COG0584	glycerophosphoryl diester phosphodiesterase
DN756_10725	COG1176	ABC-type spermidine putrescine transport system, permease component I
DN756_10730	COG3833	ABC-type maltose transport systems, permease component
DN756_10755	COG0659	secondary active sulfate transmembrane transporter activity
DN756_10765	COG2912	Transglutaminase-like superfamily
DN756_10770	COG3094	Invasion gene expression up-regulator, SirB
DN756_10775	COG2890	protein-(glutamine-N5) methyltransferase activity
DN756_10800	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DN756_10815	COG0012	GTP binding
DN756_10845	COG5002	protein histidine kinase activity
DN756_10885	COG0500	methyltransferase
DN756_10950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN756_10955	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DN756_10970	COG0402	S-adenosylhomocysteine deaminase activity
DN756_11020	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN756_11030	COG3850	Histidine kinase
DN756_11035	COG0387	Pfam Sodium calcium exchanger
DN756_11040	COG1943	Transposase
DN756_11045	COG1702	phosphate starvation-inducible protein PhoH
DN756_11060	COG3658	cytochrome
DN756_11065	COG1215	transferase activity, transferring glycosyl groups
DN756_11070	COG1649	PFAM Uncharacterised BCR, COG1649
DN756_11070	COG0726	polysaccharide deacetylase
DN756_11075	COG0457	Tetratricopeptide repeat
DN756_11080	COG0006	proline dipeptidase activity
DN756_11100	COG0577	efflux transmembrane transporter activity
DN756_11100	COG1136	(ABC) transporter
DN756_11110	COG1136	(ABC) transporter
DN756_11110	COG0577	efflux transmembrane transporter activity
DN756_11125	COG0672	)-iron permease
DN756_11135	COG2066	Belongs to the glutaminase family
DN756_11145	COG1349	DNA-binding transcription factor activity
DN756_11160	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DN756_11200	COG2030	dehydratase
DN756_11205	COG0427	acetyl-CoA hydrolase
DN756_11215	COG2205	protein histidine kinase activity
DN756_11215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN756_11230	COG3188	usher protein
DN756_11240	COG3121	Chaperone
DN756_11260	COG0395	ABC-type sugar transport system, permease component
DN756_11265	COG1175	transmembrane transport
DN756_11275	COG0673	inositol 2-dehydrogenase activity
DN756_11395	COG4974	Belongs to the 'phage' integrase family
DN756_11450	COG5002	protein histidine kinase activity
DN756_11450	COG2176	DNA-directed DNA polymerase activity
DN756_11480	COG4695	Portal protein
DN756_11655	COG2197	response regulator
DN756_11665	COG3136	membrane protein required for alginate biosynthesis
DN756_11690	COG1113	amino acid transport
DN756_11730	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DN756_11730	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DN756_11730	COG0506	proline dehydrogenase activity
DN756_11770	COG1191	sigma factor activity
DN756_11805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DN756_11810	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DN756_11830	COG1677	Flagellar hook-basal body complex protein FliE
DN756_11840	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN756_11850	COG1157	protein secretion by the type III secretion system
DN756_11855	COG2882	bacterial-type flagellum organization
DN756_11865	COG1580	Controls the rotational direction of flagella during chemotaxis
DN756_11890	COG1987	bacterial-type flagellum assembly
DN756_11905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN756_11910	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_11915	COG1129	ABC transporter
DN756_11925	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_11930	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_11930	COG3347	Dehydrogenase
DN756_11935	COG2390	Transcriptional regulator
DN756_11945	COG1256	bacterial-type flagellum assembly
DN756_11965	COG4786	Flagellar basal body rod
DN756_11975	COG1749	Flagellar hook protein flgE
DN756_11980	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DN756_11985	COG1558	bacterial-type flagellum-dependent cell motility
DN756_11990	COG1815	bacterial-type flagellum-dependent cell motility
DN756_12000	COG2747	anti-sigma28 factor FlgM
DN756_12005	COG3418	PFAM FlgN family protein
DN756_12020	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DN756_12025	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DN756_12055	COG2372	response to copper ion
DN756_12060	COG1528	Iron-storage protein
DN756_12075	COG1770	oligopeptidase
DN756_12090	COG3141	response to X-ray
DN756_12095	COG0513	Belongs to the DEAD box helicase family
DN756_12120	COG1760	l-serine dehydratase
DN756_12125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DN756_12130	COG2368	4-hydroxyphenylacetate
DN756_12145	COG3971	2-oxopent-4-enoate hydratase activity
DN756_12155	COG3384	dioxygenase
DN756_12160	COG1012	belongs to the aldehyde dehydrogenase family
DN756_12175	COG1846	Transcriptional regulator
DN756_12185	COG1253	flavin adenine dinucleotide binding
DN756_12190	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN756_12190	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN756_12195	COG3715	PTS system
DN756_12200	COG3716	PTS system mannose fructose sorbose family IID component
DN756_12220	COG5001	Diguanylate cyclase
DN756_12220	COG3447	MASE1 domain protein
DN756_12220	COG5002	protein histidine kinase activity
DN756_12230	COG2226	methyltransferase
DN756_12240	COG1278	Cold shock
DN756_12260	COG1113	amino acid transport
DN756_12300	COG2207	Transcriptional regulator
DN756_12310	COG1132	(ABC) transporter
DN756_12345	COG2223	nitrite transmembrane transporter activity
DN756_12365	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
DN756_12390	COG3122	Protein conserved in bacteria
DN756_12410	COG0534	Mate efflux family protein
DN756_12430	COG4948	Mandelate Racemase Muconate Lactonizing
DN756_12440	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_12450	COG3011	Protein conserved in bacteria
DN756_12455	COG2271	Major facilitator Superfamily
DN756_12460	COG1388	LysM domain
DN756_12460	COG1470	cell adhesion involved in biofilm formation
DN756_12475	COG2925	Exonuclease
DN756_12490	COG0531	amino acid
DN756_12500	COG0371	Dehydrogenase
DN756_12505	COG1129	ABC transporter
DN756_12510	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_12515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN756_12530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DN756_12545	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DN756_12560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DN756_12560	COG0140	phosphoribosyl-ATP diphosphatase activity
DN756_12570	COG1943	Transposase
DN756_12580	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DN756_12585	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DN756_12590	COG4264	IucA IucC family
DN756_12600	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN756_12605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN756_12610	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN756_12615	COG1120	ATPase activity
DN756_12630	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DN756_12635	COG0076	glutamate decarboxylase activity
DN756_12640	COG4114	ferric iron reductase
DN756_12645	COG1253	flavin adenine dinucleotide binding
DN756_12650	COG2982	Protein involved in outer membrane biogenesis
DN756_12665	COG0489	protein tyrosine kinase activity
DN756_12690	COG2814	Major facilitator Superfamily
DN756_12700	COG1346	cytolysis
DN756_12715	COG2949	membrane
DN756_12720	COG4211	Belongs to the binding-protein-dependent transport system permease family
DN756_12735	COG2311	Membrane
DN756_12745	COG0477	Major facilitator Superfamily
DN756_12750	COG0583	DNA-binding transcription factor activity
DN756_12780	COG1136	(ABC) transporter
DN756_12790	COG0303	'Molybdopterin
DN756_12805	COG0488	(ABC) transporter
DN756_12905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DN756_12910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DN756_12920	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_12925	COG1024	Enoyl-CoA hydratase
DN756_12935	COG3425	synthase
DN756_12940	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_12945	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DN756_12950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DN756_12960	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_12985	COG2920	part of a sulfur-relay system
DN756_13005	COG1832	CoA-binding protein
DN756_13010	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DN756_13020	COG0210	DNA helicase
DN756_13025	COG3304	Inner membrane component domain
DN756_13030	COG1289	transmembrane transporter activity
DN756_13035	COG3070	regulator of competence-specific genes
DN756_13045	COG2885	chlorophyll binding
DN756_13045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DN756_13050	COG1943	Transposase
DN756_13060	COG1067	ATP-dependent peptidase activity
DN756_13075	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DN756_13080	COG3130	regulation of translation
DN756_13090	COG3009	Protein conserved in bacteria
DN756_13095	COG3008	intermembrane lipid transfer
DN756_13095	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DN756_13100	COG2995	paraquat-inducible protein a
DN756_13105	COG0488	(ABC) transporter
DN756_13115	COG0633	Ferredoxin
DN756_13115	COG3217	Mosc domain protein beta barrel domain protein
DN756_13130	COG0308	aminopeptidase N
DN756_13150	COG1448	Aminotransferase
DN756_13155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN756_13160	COG3108	Peptidase M15
DN756_13165	COG2989	Protein conserved in bacteria
DN756_13175	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
DN756_13180	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
DN756_13185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DN756_13195	COG3173	Aminoglycoside phosphotransferase
DN756_13210	COG2835	tetraacyldisaccharide 4'-kinase activity
DN756_13215	COG1278	Cold shock
DN756_13225	COG5383	Protein conserved in bacteria
DN756_13255	COG0539	negative regulation of cytoplasmic translation
DN756_13285	COG0252	asparaginase activity
DN756_13290	COG1944	ATP diphosphatase activity
DN756_13295	COG2116	formate transmembrane transporter activity
DN756_13300	COG1882	Formate acetyltransferase
DN756_13310	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DN756_13325	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DN756_13335	COG1674	ftsk spoiiie
DN756_13335	COG3107	peptidoglycan biosynthetic process
DN756_13345	COG0492	ferredoxin-NADP+ reductase activity
DN756_13355	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
DN756_13365	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DN756_13370	COG0542	response to heat
DN756_13385	COG1278	Cold shock
DN756_13395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN756_13400	COG2990	Protein conserved in bacteria
DN756_13405	COG3593	DNA synthesis involved in DNA repair
DN756_13410	COG2431	L-lysine efflux transmembrane transporter activity
DN756_13420	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN756_13425	COG0028	Belongs to the TPP enzyme family
DN756_13430	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
DN756_13435	COG0702	epimerase
DN756_13440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN756_13450	COG1605	Chorismate mutase
DN756_13455	COG1126	abc transporter atp-binding protein
DN756_13460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN756_13465	COG4215	(ABC) transporter
DN756_13470	COG4160	amino acid transport
DN756_13490	COG1120	ATPase activity
DN756_13495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN756_13515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN756_13530	COG1177	transmembrane transport
DN756_13535	COG1176	ABC-type spermidine putrescine transport system, permease component I
DN756_13540	COG3842	ATPase activity
DN756_13545	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DN756_13570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DN756_13575	COG0569	domain protein
DN756_13575	COG2985	domain, Protein
DN756_13590	COG0671	phosphoesterase, PA-phosphatase related
DN756_13595	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DN756_13600	COG1349	DNA-binding transcription factor activity
DN756_13605	COG0814	amino acid
DN756_13610	COG1686	Belongs to the peptidase S11 family
DN756_13615	COG2011	ABC-type metal ion transport system permease component
DN756_13640	COG0625	glutathione transferase activity
DN756_13645	COG4771	TonB-dependent receptor
DN756_13655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN756_13665	COG0833	amino acid
DN756_13670	COG0583	DNA-binding transcription factor activity
DN756_13675	COG2855	membrane
DN756_13685	COG3188	usher protein
DN756_13690	COG3121	Chaperone
DN756_13705	COG3710	Transcriptional regulator
DN756_13710	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN756_13710	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN756_13710	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DN756_13715	COG1105	Belongs to the carbohydrate kinase PfkB family
DN756_13725	COG0494	nUDIX hydrolase
DN756_13730	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_13735	COG1129	ABC transporter
DN756_13745	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DN756_13770	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_13790	COG1312	Catalyzes the dehydration of D-mannonate
DN756_13795	COG0246	Mannitol dehydrogenase
DN756_13800	COG2186	Transcriptional regulator
DN756_13810	COG0523	cobalamin synthesis protein
DN756_13815	COG0671	phosphoesterase, PA-phosphatase related
DN756_13820	COG0791	NLP P60 protein
DN756_13825	COG2200	EAL domain
DN756_13830	COG4166	transmembrane transport
DN756_13835	COG4174	ABC transporter (Permease)
DN756_13840	COG4239	(ABC) transporter, permease
DN756_13845	COG4172	Belongs to the ABC transporter superfamily
DN756_13855	COG2814	Major facilitator Superfamily
DN756_13860	COG1187	pseudouridine synthase activity
DN756_13865	COG1061	Type III restriction enzyme res subunit
DN756_13880	COG3082	Protein of unknown function (DUF1414)
DN756_13885	COG3083	sulfuric ester hydrolase activity
DN756_13930	COG2723	6-phospho-beta-galactosidase activity
DN756_13935	COG1737	Transcriptional regulator
DN756_13955	COG3299	homolog of phage Mu protein gp47
DN756_13995	COG4386	tail sheath protein
DN756_14015	COG3622	Belongs to the hyi family
DN756_14020	COG1349	DNA-binding transcription factor activity
DN756_14030	COG3395	kinase activity
DN756_14075	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN756_14100	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
DN756_14105	COG2223	nitrite transmembrane transporter activity
DN756_14110	COG2198	Histidine kinase
DN756_14110	COG0642	Histidine kinase
DN756_14120	COG2205	protein histidine kinase activity
DN756_14120	COG0784	Response regulator, receiver
DN756_14145	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN756_14165	COG0814	amino acid
DN756_14190	COG0697	spore germination
DN756_14200	COG1982	Orn Lys Arg decarboxylase major
DN756_14205	COG0531	amino acid
DN756_14210	COG1174	glycine betaine transport
DN756_14215	COG1125	glycine betaine transport
DN756_14220	COG1174	glycine betaine transport
DN756_14225	COG1732	Glycine betaine
DN756_14230	COG2897	thiosulfate sulfurtransferase activity
DN756_14245	COG0410	ABC transporter
DN756_14250	COG1122	ATPase activity
DN756_14270	COG4807	Protein conserved in bacteria
DN756_14285	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DN756_14295	COG2261	transglycosylase associated protein
DN756_14305	COG1403	HNH endonuclease
DN756_14315	COG0277	FAD linked oxidase domain protein
DN756_14320	COG1686	Belongs to the peptidase S11 family
DN756_14330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN756_14340	COG1943	Transposase
DN756_14385	COG0513	Belongs to the DEAD box helicase family
DN756_14390	COG1309	transcriptional regulator
DN756_14400	COG1131	(ABC) transporter
DN756_14405	COG0842	Transport permease protein
DN756_14410	COG0842	Transport permease protein
DN756_14430	COG1902	pentaerythritol trinitrate reductase activity
DN756_14450	COG2211	Major facilitator Superfamily
DN756_14455	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DN756_14465	COG0583	DNA-binding transcription factor activity
DN756_14470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN756_14490	COG0670	Belongs to the BI1 family
DN756_14495	COG0314	molybdopterin synthase activity
DN756_14500	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DN756_14510	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DN756_14515	COG0391	Required for morphogenesis under gluconeogenic growth conditions
DN756_14520	COG4628	conserved protein (DUF2132)
DN756_14535	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DN756_14540	COG2226	methyltransferase
DN756_14565	COG0561	phosphatase activity
DN756_14575	COG4149	molybdate abc transporter
DN756_14580	COG0725	ABC transporter, periplasmic molybdate-binding protein
DN756_14590	COG3585	molybdate ion transport
DN756_14590	COG2005	Transcriptional regulator
DN756_14595	COG1119	ATPase activity
DN756_14605	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DN756_14610	COG1085	galactose-1-phosphate uridylyltransferase
DN756_14620	COG2017	converts alpha-aldose to the beta-anomer
DN756_14640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DN756_14645	COG1230	cation diffusion facilitator family transporter
DN756_14690	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DN756_14695	COG2885	chlorophyll binding
DN756_14705	COG3064	Membrane
DN756_14705	COG3064	Membrane
DN756_14710	COG0848	biopolymer transport protein
DN756_14715	COG0811	peptide transport
DN756_14720	COG0824	Thioesterase
DN756_14725	COG3790	cyd operon protein YbgE
DN756_14730	COG4890	Cyd operon protein YbgT
DN756_14735	COG1294	oxidase, subunit
DN756_14740	COG1271	oxidase subunit
DN756_14745	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
DN756_14755	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN756_14760	COG0567	Dehydrogenase, E1 component
DN756_14770	COG1053	succinate dehydrogenase
DN756_14775	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DN756_14780	COG2009	succinate dehydrogenase
DN756_14795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DN756_14800	COG0497	DNA recombination
DN756_14805	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DN756_14815	COG2867	negative regulation of translational initiation
DN756_14830	COG0582	viral genome integration into host DNA
DN756_14840	COG0582	viral genome integration into host DNA
DN756_14850	COG0596	Alpha beta hydrolase
DN756_14870	COG0735	belongs to the Fur family
DN756_14890	COG1943	Transposase
DN756_14900	COG2190	(PTS) system
DN756_14900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DN756_14900	COG1263	PTS System
DN756_14910	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DN756_14915	COG1846	Transcriptional regulator
DN756_14915	COG1940	carbohydrate kinase activity
DN756_14920	COG0647	UMP catabolic process
DN756_14925	COG0367	asparagine synthase
DN756_14965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DN756_14975	COG1702	phosphate starvation-inducible protein PhoH
DN756_14985	COG4535	Mg2 and Co2 transporter CorC
DN756_14990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DN756_15000	COG0765	amino acid transport
DN756_15005	COG0765	amino acid transport
DN756_15010	COG1126	abc transporter atp-binding protein
DN756_15015	COG2888	peptidyl-tyrosine sulfation
DN756_15030	COG1466	dna polymerase III delta subunit
DN756_15040	COG0799	negative regulation of ribosome biogenesis
DN756_15050	COG0768	penicillin binding
DN756_15055	COG0772	Belongs to the SEDS family
DN756_15060	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DN756_15065	COG1686	Belongs to the peptidase S11 family
DN756_15090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DN756_15095	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
DN756_15100	COG1278	Cold shock
DN756_15105	COG1278	Cold shock
DN756_15110	COG2197	response regulator
DN756_15135	COG5265	(ABC) transporter
DN756_15145	COG3718	enzyme involved in inositol metabolism
DN756_15155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN756_15160	COG0673	inositol 2-dehydrogenase activity
DN756_15165	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_15170	COG1129	ABC transporter
DN756_15175	COG1879	ABC-type sugar transport system periplasmic component
DN756_15180	COG0673	inositol 2-dehydrogenase activity
DN756_15185	COG3962	Belongs to the TPP enzyme family
DN756_15205	COG2373	Large extracellular alpha-helical protein
DN756_15210	COG4953	penicillin-binding protein 1C
DN756_15215	COG3423	Transcriptional regulator
DN756_15265	COG2850	peptidyl-arginine hydroxylation
DN756_15275	COG3328	transposase activity
DN756_15280	COG1187	pseudouridine synthase activity
DN756_15305	COG0656	L-ascorbic acid biosynthetic process
DN756_15310	COG0667	Aldo Keto reductase
DN756_15330	COG0671	phosphoesterase, PA-phosphatase related
DN756_15330	COG2453	phosphatase
DN756_15335	COG2267	carboxylic ester hydrolase activity
DN756_15345	COG4589	Belongs to the CDS family
DN756_15350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DN756_15365	COG0582	viral genome integration into host DNA
DN756_15545	COG4386	tail sheath protein
DN756_15580	COG0582	viral genome integration into host DNA
DN756_15605	COG2003	Belongs to the UPF0758 family
DN756_15635	COG3596	GTP binding
DN756_15690	COG0582	viral genome integration into host DNA
DN756_15695	COG0582	viral genome integration into host DNA
DN756_15710	COG2501	S4 domain
DN756_15720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DN756_15735	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DN756_15740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DN756_15745	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DN756_15750	COG4181	ATPase activity
DN756_15755	COG2755	lipolytic protein G-D-S-L family
DN756_15760	COG0300	oxidoreductase activity
DN756_15765	COG3118	belongs to the thioredoxin family
DN756_15770	COG0330	HflC and HflK could
DN756_15775	COG1585	Membrane protein implicated in regulation of membrane protease activity
DN756_15780	COG0789	Transcriptional regulator
DN756_15785	COG2217	Heavy metal translocating P-type atpase
DN756_15790	COG3735	TraB family
DN756_15795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DN756_15805	COG0737	Belongs to the 5'-nucleotidase family
DN756_15810	COG0737	Belongs to the 5'-nucleotidase family
DN756_15820	COG1943	Transposase
DN756_15830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN756_15830	COG4651	solute:proton antiporter activity
DN756_15835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN756_15840	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
DN756_15850	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN756_15865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN756_15870	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DN756_15885	COG2244	polysaccharide biosynthetic process
DN756_15895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN756_15915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN756_15915	COG0543	2 iron, 2 sulfur cluster binding
DN756_15945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DN756_15955	COG2832	Protein of unknown function (DUF454)
DN756_15970	COG1196	nuclear chromosome segregation
DN756_15970	COG3264	Mechanosensitive ion channel
DN756_15975	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DN756_15980	COG1309	transcriptional regulator
DN756_15985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN756_15990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN756_16000	COG1943	Transposase
DN756_16010	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DN756_16035	COG3695	enzyme binding
DN756_16040	COG3126	Type III secretion system lipoprotein chaperone (YscW)
DN756_16045	COG1946	Acyl-CoA thioesterase
DN756_16050	COG0004	ammonium transporteR
DN756_16055	COG0347	Belongs to the P(II) protein family
DN756_16060	COG1132	(ABC) transporter
DN756_16065	COG1132	(ABC) transporter
DN756_16070	COG1522	sequence-specific DNA binding
DN756_16085	COG4533	DNA binding
DN756_16095	COG0824	Thioesterase
DN756_16100	COG1555	photosystem II stabilization
DN756_16105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DN756_16110	COG0776	regulation of translation
DN756_16115	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DN756_16140	COG0271	Belongs to the BolA IbaG family
DN756_16145	COG3056	Lipoprotein
DN756_16150	COG2223	nitrite transmembrane transporter activity
DN756_16160	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DN756_16165	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DN756_16170	COG1845	cytochrome c oxidase, subunit III
DN756_16175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DN756_16185	COG2814	Major facilitator Superfamily
DN756_16200	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DN756_16205	COG0693	protein deglycase activity
DN756_16220	COG0142	geranyltranstransferase activity
DN756_16230	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DN756_16235	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DN756_16250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN756_16250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN756_16270	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DN756_16275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DN756_16280	COG1862	Preprotein translocase
DN756_16300	COG0450	alkyl hydroperoxide reductase
DN756_16315	COG0300	oxidoreductase activity
DN756_16325	COG0366	Alpha amylase catalytic
DN756_16335	COG1114	Component of the transport system for branched-chain amino acids
DN756_16345	COG5002	protein histidine kinase activity
DN756_16350	COG0745	RESPONSE REGULATOR receiver
DN756_16355	COG0420	3'-5' exonuclease activity
DN756_16360	COG0419	ATPase involved in DNA repair
DN756_16365	COG1940	carbohydrate kinase activity
DN756_16395	COG2226	methyltransferase
DN756_16445	COG0583	DNA-binding transcription factor activity
DN756_16450	COG2195	Cleaves the N-terminal amino acid of tripeptides
DN756_16470	COG1477	protein flavinylation
DN756_16490	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DN756_16495	COG1805	sodium ion transport
DN756_16500	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
DN756_16510	COG3034	peptidoglycan biosynthetic process
DN756_16515	COG0121	glutamine amidotransferase
DN756_16525	COG1960	acyl-CoA dehydrogenase activity
DN756_16535	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
DN756_16555	COG1943	Transposase
DN756_16585	COG0436	Aminotransferase
DN756_16600	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DN756_16650	COG2814	Major facilitator Superfamily
DN756_16655	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DN756_16665	COG1846	Transcriptional regulator
DN756_16675	COG1566	PFAM secretion protein HlyD family protein
DN756_16680	COG2814	Major facilitator Superfamily
DN756_16685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN756_16690	COG3118	belongs to the thioredoxin family
DN756_16700	COG0045	succinate-CoA ligase (ADP-forming) activity
DN756_16700	COG1042	CoA-binding domain protein
DN756_16700	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DN756_16705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN756_16710	COG5544	Lipoprotein
DN756_16750	COG0542	response to heat
DN756_16760	COG0564	pseudouridine synthase activity
DN756_16770	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DN756_16775	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DN756_16780	COG0077	Prephenate dehydratase
DN756_16780	COG1605	Chorismate mutase
DN756_16785	COG0287	Prephenate dehydrogenase
DN756_16785	COG1605	Chorismate mutase
DN756_16790	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DN756_16795	COG3279	Response regulator of the LytR AlgR family
DN756_16800	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DN756_16805	COG3137	Salt-induced outer membrane protein
DN756_16830	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DN756_16835	COG4137	Cytochrome C assembly protein
DN756_16840	COG4536	flavin adenine dinucleotide binding
DN756_16855	COG1238	metal cluster binding
DN756_16860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN756_16890	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
DN756_16935	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DN756_16940	COG3958	Transketolase
DN756_16945	COG3959	Transketolase, thiamine diphosphate binding domain
DN756_16950	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_16955	COG1129	ABC transporter
DN756_16975	COG3783	Cytochrome b(562)
DN756_16980	COG3038	cytochrome b561
DN756_16985	COG3381	protein complex oligomerization
DN756_16990	COG3302	dmso reductase anchor subunit
DN756_16995	COG0437	4 iron, 4 sulfur cluster binding
DN756_17000	COG0243	molybdopterin cofactor binding
DN756_17005	COG0235	Class ii aldolase
DN756_17010	COG1349	DNA-binding transcription factor activity
DN756_17020	COG1129	ABC transporter
DN756_17025	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_17030	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_17035	COG3623	hexulose-6-phosphate isomerase
DN756_17040	COG1070	Carbohydrate kinase
DN756_17045	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DN756_17045	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DN756_17055	COG0024	Methionine aminopeptidase
DN756_17065	COG4771	TonB-dependent receptor
DN756_17075	COG1858	cytochrome C peroxidase
DN756_17080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN756_17100	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DN756_17115	COG2376	Dihydroxyacetone kinase
DN756_17120	COG1028	Short-chain dehydrogenase reductase Sdr
DN756_17125	COG1063	alcohol dehydrogenase
DN756_17130	COG0698	ribose 5-phosphate isomerase
DN756_17140	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DN756_17145	COG4942	peptidase
DN756_17145	COG1388	LysM domain
DN756_17185	COG0529	Catalyzes the synthesis of activated sulfate
DN756_17240	COG0720	synthase
DN756_17245	COG0602	queuosine metabolic process
DN756_17265	COG3956	TIGRFAM MazG family protein
DN756_17270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DN756_17275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DN756_17285	COG2205	protein histidine kinase activity
DN756_17285	COG3437	response regulator, receiver
DN756_17285	COG3850	Histidine kinase
DN756_17285	COG4999	Histidine kinase
DN756_17290	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN756_17310	COG2860	membrane
DN756_17330	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN756_17335	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DN756_17340	COG1120	ATPase activity
DN756_17345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN756_17350	COG1643	Atp-dependent helicase
DN756_17355	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
DN756_17370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DN756_17380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DN756_17385	COG0617	tRNA 3'-terminal CCA addition
DN756_17390	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DN756_17410	COG0726	polysaccharide deacetylase
DN756_17415	COG0842	Transport permease protein
DN756_17420	COG1131	(ABC) transporter
DN756_17425	COG0288	reversible hydration of carbon dioxide
DN756_17430	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DN756_17435	COG2132	Multicopper oxidase
DN756_17455	COG0697	spore germination
DN756_17465	COG1049	propionate catabolic process, 2-methylcitrate cycle
DN756_17475	COG1943	Transposase
DN756_17480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN756_17485	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN756_17490	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
DN756_17495	COG2186	Transcriptional regulator
DN756_17505	COG1113	amino acid transport
DN756_17510	COG3725	Membrane protein required for beta-lactamase induction
DN756_17515	COG3023	N-Acetylmuramoyl-L-alanine amidase
DN756_17525	COG4969	Belongs to the N-Me-Phe pilin family
DN756_17530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DN756_17535	COG1459	type II secretion system
DN756_17550	COG0237	dephospho-CoA kinase activity
DN756_17565	COG1943	Transposase
DN756_17575	COG0494	nUDIX hydrolase
DN756_17605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DN756_17610	COG0849	cell division
DN756_17615	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DN756_17635	COG0772	Belongs to the SEDS family
DN756_17650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DN756_17655	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DN756_17660	COG0768	penicillin binding
DN756_17665	COG3116	cell division
DN756_17690	COG1609	Transcriptional regulator
DN756_17705	COG0028	Belongs to the TPP enzyme family
DN756_17715	COG1022	Amp-dependent synthetase and ligase
DN756_17740	COG0473	3-isopropylmalate dehydrogenase activity
DN756_17755	COG2814	Major facilitator Superfamily
DN756_17770	COG4143	(ABC) transporter
DN756_17775	COG1178	ABC-type Fe3 transport system permease component
DN756_17785	COG0586	Pfam SNARE associated Golgi protein
DN756_17790	COG0417	DNA replication proofreading
DN756_17810	COG2885	chlorophyll binding
DN756_17810	COG3047	cAMP biosynthetic process
DN756_17845	COG3501	Rhs element vgr protein
DN756_17895	COG0564	pseudouridine synthase activity
DN756_17900	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DN756_17910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DN756_17950	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DN756_17960	COG2966	Psort location CytoplasmicMembrane, score
DN756_17970	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
DN756_17975	COG0505	Belongs to the CarA family
DN756_17995	COG1047	Peptidyl-prolyl cis-trans
DN756_18010	COG0196	riboflavin kinase activity
DN756_18030	COG0583	DNA-binding transcription factor activity
DN756_18050	COG1584	GPR1 FUN34 yaaH family protein
DN756_18065	COG0521	Mo-molybdopterin cofactor biosynthetic process
DN756_18105	COG0745	RESPONSE REGULATOR receiver
DN756_18110	COG3045	CreA protein
DN756_18120	COG3708	Transcriptional regulator
DN756_18120	COG2207	Transcriptional regulator
DN756_18135	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
DN756_18140	COG0741	lytic transglycosylase activity
DN756_18155	COG2199	diguanylate cyclase activity
DN756_18160	COG2885	chlorophyll binding
DN756_18165	COG0488	(ABC) transporter
DN756_18185	COG0560	Phosphoserine phosphatase
DN756_18190	COG3726	membrane protein affecting hemolysin expression
DN756_18210	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DN756_18215	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
DN756_18220	COG0084	hydrolase, TatD family'
DN756_18225	COG4667	esterase of the alpha-beta hydrolase superfamily
DN756_18235	COG2823	Periplasmic or secreted lipoprotein
DN756_18245	COG0456	acetyltransferase
DN756_18250	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
DN756_18280	COG3706	GGDEF domain
DN756_18305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN756_18310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN756_18330	COG0859	PFAM glycosyl transferase family 9
DN756_18340	COG2390	Transcriptional regulator
DN756_18385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN756_18385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DN756_18385	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN756_18390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN756_18395	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN756_18400	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN756_18405	COG2207	Transcriptional regulator
DN756_18415	COG4269	membrane
DN756_18470	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DN756_18480	COG0582	viral genome integration into host DNA
DN756_18490	COG0795	lipopolysaccharide-transporting ATPase activity
DN756_18495	COG0795	lipopolysaccharide-transporting ATPase activity
DN756_18505	COG2927	DNA polymerase III (CHI subunit)
DN756_18520	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
DN756_18530	COG2731	YhcH YjgK YiaL family protein
DN756_18540	COG0601	transmembrane transport
DN756_18545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN756_18550	COG0444	Belongs to the ABC transporter superfamily
DN756_18555	COG4608	Belongs to the ABC transporter superfamily
DN756_18575	COG2188	Transcriptional regulator
DN756_18580	COG3624	Phosphonate C-P lyase system protein PhnG
DN756_18585	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
DN756_18590	COG3626	phosphonate metabolism
DN756_18595	COG3627	carbon phosphorus lyase activity
DN756_18600	COG4107	phosphonate C-P lyase system protein PhnK
DN756_18605	COG4778	phosphonate C-P lyase system protein PhnL
DN756_18610	COG3454	Phosphonate metabolism
DN756_18615	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DN756_18620	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DN756_18625	COG0702	epimerase
DN756_18640	COG3842	ATPase activity
DN756_18645	COG0395	ABC-type sugar transport system, permease component
DN756_18655	COG1653	transport
DN756_18675	COG3153	acetyltransferase
DN756_18705	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN756_18715	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN756_18735	COG0513	Belongs to the DEAD box helicase family
DN756_18775	COG0195	Participates in both transcription termination and antitermination
DN756_18795	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DN756_18805	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DN756_18810	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DN756_18820	COG1534	Rna-binding protein
DN756_18825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DN756_18830	COG2027	D-alanyl-D-alanine carboxypeptidase
DN756_18835	COG0745	RESPONSE REGULATOR receiver
DN756_18840	COG0642	Histidine kinase
DN756_18900	COG0697	spore germination
DN756_18915	COG0142	geranyltranstransferase activity
DN756_18925	COG3423	Transcriptional regulator
DN756_18950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DN756_18960	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DN756_18965	COG2105	PFAM AIG2 family protein
DN756_18970	COG2911	Protein conserved in bacteria
DN756_18975	COG0729	surface antigen
DN756_18985	COG1253	flavin adenine dinucleotide binding
DN756_18995	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
DN756_19005	COG0737	Belongs to the 5'-nucleotidase family
DN756_19015	COG0545	Peptidyl-prolyl cis-trans isomerase
DN756_19020	COG3061	Opacity-associated protein A
DN756_19035	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DN756_19045	COG0360	Binds together with S18 to 16S ribosomal RNA
DN756_19055	COG1073	alpha beta
DN756_19060	COG3650	response to hydrogen peroxide
DN756_19065	COG1960	acyl-CoA dehydrogenase activity
DN756_19070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN756_19075	COG0557	exoribonuclease II activity
DN756_19090	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
DN756_19095	COG0330	HflC and HflK could
DN756_19100	COG0330	HflC and HflK could
DN756_19105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DN756_19125	COG0860	N-Acetylmuramoyl-L-alanine amidase
DN756_19130	COG0802	atpase or kinase
DN756_19135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DN756_19135	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DN756_19140	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DN756_19185	COG1511	domain protein
DN756_19185	COG3264	Mechanosensitive ion channel
DN756_19200	COG1053	succinate dehydrogenase
DN756_19205	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DN756_19215	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
DN756_19220	COG2076	Multidrug Resistance protein
DN756_19270	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
DN756_19285	COG3383	formate dehydrogenase (NAD+) activity
DN756_19290	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DN756_19295	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
DN756_19295	COG0493	'glutamate synthase
DN756_19305	COG1309	transcriptional regulator
DN756_19375	COG1454	alcohol dehydrogenase
DN756_19385	COG0629	single-stranded DNA binding
DN756_19395	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DN756_19400	COG2315	Protein conserved in bacteria
DN756_19405	COG1448	Aminotransferase
DN756_19410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN756_19415	COG0305	Participates in initiation and elongation during chromosome replication
DN756_19430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN756_19435	COG0735	belongs to the Fur family
DN756_19445	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
DN756_19500	COG3121	Chaperone
DN756_19560	COG1358	cellular component organization or biogenesis
DN756_19585	COG3721	Heme iron utilization protein
DN756_19590	COG0702	epimerase
DN756_19600	COG4771	TonB-dependent receptor
DN756_19605	COG3720	iron ion transport
DN756_19610	COG4558	Periplasmic binding protein
DN756_19615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN756_19625	COG0626	cystathionine gamma-synthase activity
DN756_19630	COG0814	amino acid
DN756_19635	COG0583	DNA-binding transcription factor activity
DN756_19640	COG0425	Belongs to the sulfur carrier protein TusA family
DN756_19645	COG2391	methyltransferase activity
DN756_19760	COG1301	dicarboxylic acid transport
DN756_19770	COG3162	membrane
DN756_19825	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
DN756_19830	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN756_19835	COG1739	Uncharacterized protein family UPF0029
DN756_19880	COG0805	protein transport
DN756_19890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DN756_19910	COG1322	Protein conserved in bacteria
DN756_19915	COG0586	Pfam SNARE associated Golgi protein
DN756_19920	COG1966	Carbon starvation protein
DN756_19930	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
DN756_19935	COG0412	Dienelactone hydrolase
DN756_19945	COG0583	DNA-binding transcription factor activity
DN756_19965	COG0679	Auxin Efflux Carrier
DN756_19970	COG0584	glycerophosphoryl diester phosphodiesterase
DN756_20035	COG0410	ABC transporter
DN756_20040	COG0411	ABC transporter
DN756_20045	COG4177	L-phenylalanine transmembrane transporter activity
DN756_20050	COG0559	Belongs to the binding-protein-dependent transport system permease family
DN756_20055	COG0683	leucine binding
DN756_20070	COG2177	Part of the ABC transporter FtsEX involved in
DN756_20075	COG2884	Cell division ATP-binding protein ftsE
DN756_20080	COG0552	protein localization to endoplasmic reticulum
DN756_20080	COG0552	protein localization to endoplasmic reticulum
DN756_20090	COG0742	ribosomal rna small subunit methyltransferase
DN756_20095	COG3776	membrane
DN756_20110	COG3714	YhhN family
DN756_20125	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
DN756_20135	COG0247	lactate metabolic process
DN756_20145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DN756_20160	COG0584	glycerophosphoryl diester phosphodiesterase
DN756_20170	COG0561	phosphatase activity
DN756_20175	COG2267	carboxylic ester hydrolase activity
DN756_20180	COG1280	lysine exporter protein (LysE YggA)
DN756_20185	COG1280	lysine exporter protein (LysE YggA)
DN756_20190	COG0514	ATP-dependent DNA helicase (RecQ)
DN756_20195	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
DN756_20200	COG2050	protein possibly involved in aromatic compounds catabolism
DN756_20210	COG0598	Magnesium transport protein CorA
DN756_20215	COG5564	TIM-barrel signal transduction protein
DN756_20220	COG5441	Belongs to the UPF0261 family
DN756_20230	COG0210	DNA helicase
DN756_20235	COG1011	Hydrolase
DN756_20240	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DN756_20245	COG3159	Protein conserved in bacteria
DN756_20255	COG5567	small periplasmic lipoprotein
DN756_20265	COG3072	Adenylate cyclase
DN756_20280	COG1587	Uroporphyrinogen-III synthase
DN756_20285	COG2959	enzyme of heme biosynthesis
DN756_20290	COG3071	HemY protein
DN756_20320	COG1113	amino acid transport
DN756_20340	COG2244	polysaccharide biosynthetic process
DN756_20345	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DN756_20350	COG0456	acetyltransferase
DN756_20355	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DN756_20360	COG1088	dTDP-glucose 4,6-dehydratase activity
DN756_20365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DN756_20370	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DN756_20375	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
DN756_20380	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DN756_20385	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DN756_20390	COG3118	belongs to the thioredoxin family
DN756_20415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DN756_20435	COG3121	Chaperone
DN756_20450	COG3121	Chaperone
DN756_20490	COG0583	DNA-binding transcription factor activity
DN756_20520	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN756_20525	COG3978	acetolactate synthase activity
DN756_20550	COG3085	chromosome segregation
DN756_20560	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_20565	COG1172	Belongs to the binding-protein-dependent transport system permease family
DN756_20570	COG1129	ABC transporter
DN756_20575	COG1879	ABC-type sugar transport system periplasmic component
DN756_20655	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DN756_20655	COG0678	peroxiredoxin activity
DN756_20660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN756_20685	COG1629	transport
DN756_20730	COG0460	homoserine dehydrogenase
DN756_20730	COG0527	aspartate kinase activity
DN756_20735	COG0626	cystathionine gamma-synthase activity
DN756_20740	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
DN756_20745	COG4682	membrane
DN756_20755	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DN756_20765	COG1609	Transcriptional regulator
DN756_20770	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DN756_20785	COG1575	Belongs to the MenA family. Type 1 subfamily
DN756_20840	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DN756_20845	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DN756_20850	COG1494	fructose-1,6-bisphosphatase
DN756_20860	COG3152	Membrane
DN756_20875	COG0583	DNA-binding transcription factor activity
DN756_20880	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DN756_20885	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DN756_20890	COG0471	metal ion transport
DN756_20900	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DN756_20930	COG3678	ATP-independent chaperone mediated protein folding
DN756_20935	COG0745	RESPONSE REGULATOR receiver
DN756_20940	COG2205	protein histidine kinase activity
DN756_20945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DN756_20945	COG2169	Transcriptional regulator
DN756_20950	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DN756_20955	COG1045	serine acetyltransferase
DN756_20975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DN756_20980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DN756_20990	COG4942	peptidase
DN756_20995	COG2861	carbohydrate metabolic process
DN756_21005	COG0156	8-amino-7-oxononanoate synthase activity
DN756_21015	COG0859	PFAM glycosyl transferase family 9
DN756_21020	COG0859	PFAM glycosyl transferase family 9
DN756_21025	COG1519	Transferase
DN756_21045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DN756_21065	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DN756_21090	COG1561	YicC-like family, N-terminal region
DN756_21145	COG2860	membrane
DN756_21150	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DN756_21160	COG1758	RNA polymerase activity
DN756_21165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DN756_21170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN756_21175	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DN756_21185	COG0786	glutamate:sodium symporter activity
DN756_21190	COG2233	PERMEase
DN756_21195	COG2982	Protein involved in outer membrane biogenesis
DN756_21200	COG0456	acetyltransferase
DN756_21215	COG1011	Hydrolase
DN756_21225	COG0174	glutamine synthetase
DN756_21235	COG3852	Histidine kinase
DN756_21245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN756_21270	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN756_21270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DN756_21275	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DN756_21280	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN756_21285	COG3084	Protein conserved in bacteria
DN756_21295	COG1763	Mo-molybdopterin cofactor biosynthetic process
DN756_21300	COG3328	transposase activity
DN756_21335	COG2186	Transcriptional regulator
DN756_21340	COG0477	Major facilitator Superfamily
DN756_21350	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN756_21380	COG1522	sequence-specific DNA binding
DN756_21385	COG0716	FMN binding
DN756_21405	COG3312	ion transport
DN756_21460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DN756_21465	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DN756_21470	COG0573	inorganic phosphate transmembrane transporter activity
DN756_21475	COG0581	inorganic phosphate transmembrane transporter activity
DN756_21485	COG0704	Plays a role in the regulation of phosphate uptake
DN756_21495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN756_21500	COG0765	amino acid transport
DN756_21505	COG0765	amino acid transport
DN756_21510	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN756_21520	COG2252	PERMEase
DN756_21550	COG0706	membrane insertase activity
DN756_21565	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DN756_21730	COG5599	Phosphatase
DN756_21740	COG3609	addiction module antidote protein, CC2985 family
DN756_21755	COG1475	DNA binding
DN756_21760	COG1192	Involved in chromosome partitioning
DN756_21815	COG3328	transposase activity
DN756_21825	COG4886	Leucine-rich repeat (LRR) protein
DN756_21870	COG4789	Type iii secretion
DN756_21915	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DN756_21920	COG4790	Type iii secretion
DN756_21925	COG4794	Type iii secretion
DN756_21930	COG4791	protein targeting
DN756_21935	COG4792	protein secretion
DN756_21945	COG2207	Transcriptional regulator
DN756_21995	COG4669	(LipO)protein
DN756_22005	COG1317	bacterial-type flagellum organization
DN756_22010	COG5599	Phosphatase
