locus-tag class description BZ21_1 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase BZ21_10 ENOG4107KGK dmso reductase anchor subunit BZ21_100 ENOG4105EIB trna rrna methyltransferase BZ21_1002 ENOG4105C1J atp-dependent rna helicase BZ21_1003 ENOG4105X2V dna damage-inducible protein BZ21_1006 ENOG4105CUG Oligopeptidase b BZ21_1008 ENOG4105MPK DNA polymerase III subunit theta BZ21_1009 ENOG41090A1 ferritin BZ21_101 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ21_1010 ENOG4105FXM Copper resistance protein BZ21_1012 ENOG4105NKT exported protein BZ21_1017 ENOG4105D00 flagellar biosynthetic protein flhB BZ21_1018 ENOG4105D7B Flagellar biosynthesis protein flha BZ21_1019 ENOG4105W13 flagellar protein BZ21_102 ENOG4105CW7 secretion protein, HlyD family BZ21_1021 ENOG4105QVD Flagella synthesis protein FlgN BZ21_1022 ENOG4105M9M anti-sigma28 factor FlgM BZ21_1023 ENOG4105CKS Flagella basal body P-ring formation protein flgA BZ21_1024 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ21_1025 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ21_1026 ENOG4105W00 Flagellar hook capping protein BZ21_1027 ENOG4105BZE flagellar hook protein, FlgE BZ21_1028 ENOG4108KPB Flagellar basal-body rod protein FlgF BZ21_1029 ENOG4105CGA flagellar basal-body rod protein FlgG BZ21_103 ENOG4105NTK Transcriptional repressor Mpra BZ21_1032 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BZ21_1033 ENOG4105E1Q flagellar hook-associated protein BZ21_1034 ENOG4105DTJ flagellar hook-associated protein BZ21_1035 ENOG4105DKT Transcriptional regulator BZ21_1038 ENOG4105CNN ABC, transporter BZ21_104 ENOG4105ZED uncharacterized protein ygaH BZ21_1040 ENOG4105C2J ABC transporter BZ21_1041 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BZ21_1042 ENOG4108MGF sugar kinase BZ21_1045 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ21_1046 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ21_1047 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ21_1049 ENOG4105DD5 Flagellar motor switch protein BZ21_105 ENOG4108UMN azlc family BZ21_1050 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ21_1051 ENOG4107ZI8 flagellar basal body-associated protein flil BZ21_1052 ENOG4105WF4 Flagellar hook-length control protein BZ21_1053 ENOG4105GSA Flagellar export protein flij BZ21_1054 ENOG4108JIR Flagellum-specific ATP synthase BZ21_1055 ENOG41090PJ Flagellar assembly protein BZ21_1056 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ21_1057 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ21_1058 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BZ21_106 ENOG4105EQ0 Major Facilitator superfamily BZ21_1062 ENOG4105DHT Metal Dependent Phosphohydrolase BZ21_1065 ENOG4105MQ3 flagellar protein FliS BZ21_1066 ENOG4105DTS flagellar hook-associated BZ21_1067 ENOG4105I03 Flagellin BZ21_1068 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ21_1069 ENOG4108M9K flagella biosynthesis protein FliZ BZ21_1071 ENOG4105EAB amino acid AbC transporter BZ21_1072 ENOG4105E5Q amino acid AbC transporter BZ21_1073 ENOG4105CDA abc transporter atp-binding protein BZ21_1076 ENOG4105C26 Dehydrogenase BZ21_1078 ENOG4105CK7 Sodium proline symporter BZ21_1084 ENOG4105C85 amino acid BZ21_1086 ENOG4108T1M outer membrane protein x BZ21_1088 ENOG4105RA2 Membrane BZ21_1089 ENOG4105XVG cytoplasmic protein BZ21_1090 ENOG4105WH1 Two component transcriptional regulator luxr family BZ21_1096 ENOG4105ZTC transcriptional activator, Ogr delta BZ21_11 ENOG4108NEM leader-binding protein dmsD BZ21_111 ENOG4105F87 Dehydratase BZ21_1123 ENOG4105ED4 portal protein BZ21_1126 ENOG4105VZ1 Replication Protein BZ21_1128 ENOG4105DFE Dna adenine methylase BZ21_1129 ENOG4108IRC dna polymerase iii BZ21_113 ENOG4105E5Q amino acid AbC transporter BZ21_1143 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ21_115 ENOG4105C5R Aminotransferase BZ21_1150 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ21_118 ENOG4105CHM Aminotransferase BZ21_1181 ENOG4105FDP GntR family transcriptional regulator BZ21_1182 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BZ21_1185 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BZ21_1186 ENOG4108IJ9 (ABC) transporter BZ21_1188 ENOG4108MQF Chaperone BZ21_1190 ENOG4105CW0 outer membrane usher protein BZ21_1193 ENOG4105BZU Histidine kinase BZ21_1194 ENOG4108Q9V regulatoR BZ21_1195 ENOG4105CYC Transferase BZ21_1196 ENOG4105DJG MaoC domain protein dehydratase BZ21_12 ENOG4105CPW cytochrome b561 BZ21_1201 ENOG4107RGD Major Facilitator superfamily BZ21_1204 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ21_1205 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BZ21_1206 ENOG4105C85 amino acid BZ21_1207 ENOG4105MVE transcriptional regulator BZ21_1208 ENOG4105CSV Glutaminase BZ21_1210 ENOG4107SJW iron permease, FTR1 BZ21_1213 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BZ21_1215 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BZ21_1219 ENOG4105H1N peptidase, M24 BZ21_1220 ENOG4108TUY outer membrane protein PgaA BZ21_1221 ENOG4107BJW polysaccharide deacetylase BZ21_1222 ENOG4105CND Glycosyl transferase, family 2 BZ21_1223 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD BZ21_1226 ENOG4105D5M phosphate starvation-inducible protein BZ21_1227 ENOG4105EWV Sodium calcium exchanger membrane region BZ21_1228 ENOG4105BZU Histidine kinase BZ21_1229 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BZ21_1240 ENOG4105FCK Membrane BZ21_1243 ENOG4105CZE histidine utilization repressor BZ21_1244 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BZ21_1247 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BZ21_1248 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ21_126 ENOG4106YJS accessory processing protein BZ21_1261 ENOG4108WF3 methyltransferase BZ21_1270 ENOG4105GR3 Histidine kinase BZ21_1272 ENOG4105ENX hydrolase BZ21_1276 ENOG4105C3G gtp-binding protein BZ21_1278 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria BZ21_1279 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BZ21_128 ENOG4107QPN acyl-Coa dehydrogenase BZ21_1284 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BZ21_1285 ENOG4108YY7 Invasion gene expression up-regulator SirB BZ21_1286 ENOG41063JG Transcriptional regulator BZ21_1288 ENOG4105CHH sulfate transporter BZ21_1292 ENOG4105EG2 ABC transporter, permease BZ21_1293 ENOG4105F38 ABC transporter, permease BZ21_1295 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BZ21_1296 ENOG4105E2R ROK family BZ21_1299 ENOG4107XHZ cytoplasmic chaperone TorD family protein BZ21_13 ENOG4108XVM Cytochrome b(562) BZ21_130 ENOG4105F7V ErfK ybiS ycfS ynhG family protein BZ21_1300 ENOG4105F3T (LipO)protein BZ21_1302 ENOG4105D9U N-acetyltransferase BZ21_1305 ENOG4105CJR Integral membrane protein (MviN BZ21_1309 ENOG4106ZCM YecM protein BZ21_131 ENOG4105E7A Glutamine amidotransferase BZ21_1313 ENOG4105WJG Glutathione BZ21_1314 ENOG41081XQ Conserved Protein BZ21_1316 ENOG4108TIT dATP pyrophosphohydrolase BZ21_132 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ21_1321 ENOG4105FAV ABC, transporter BZ21_1323 ENOG4105NXV High-affinity zinc uptake system protein BZ21_1324 ENOG4105DR5 peptidase BZ21_1325 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BZ21_1326 ENOG4105CA9 Pyruvate kinase BZ21_1327 ENOG4106KNT transcriptional regulator BZ21_1328 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BZ21_133 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ21_1330 ENOG4108UHU Aldolase BZ21_1333 ENOG4105M4H endoribonuclease L-psp BZ21_1334 ENOG4105DVT helicase BZ21_1335 ENOG41072GX Peptidase M22 Glycoprotease BZ21_1336 ENOG4105Y4Z Outer Membrane Lipoprotein BZ21_1337 ENOG4105CEY Amp-dependent synthetase and ligase BZ21_1338 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BZ21_1339 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) BZ21_134 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ21_1340 ENOG4107QMS site-determining protein BZ21_1343 ENOG4105CVE Lytic murein transglycosylase BZ21_1344 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BZ21_1347 ENOG4105C3J Cysteine desulfurase BZ21_1353 ENOG4105ED1 spovr family BZ21_1355 ENOG4105CNH Multidrug resistance protein MdtL BZ21_1356 ENOG4105EUB pirin domain protein BZ21_1357 ENOG4105HEI LysR family (Transcriptional regulator BZ21_1360 ENOG4105CYN Serine protein kinase BZ21_1361 ENOG4105GNX MltA-interacting MipA family protein BZ21_1362 ENOG4105DSB aldose 1-epimerase BZ21_1365 ENOG4105VUT cytoplasmic protein BZ21_1366 ENOG4108RWI nicotinamidase BZ21_1367 ENOG4105HDK L-asparaginase BZ21_1368 ENOG4105D07 Signal peptide peptidase, SppA BZ21_1369 ENOG41069NU Nitroreductase BZ21_1371 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ21_1372 ENOG4105MTM Protein of unknown function (DUF1496) BZ21_1373 ENOG4105M6F mutator MutT protein BZ21_1374 ENOG4105CGK Exodeoxyribonuclease III BZ21_1375 ENOG4105SKE transcriptional Regulator LysR family BZ21_1378 ENOG4105CIY formyltetrahydrofolate deformylase BZ21_138 ENOG4105CJ2 (LipO)protein BZ21_1380 ENOG4105I93 response regulator BZ21_1381 ENOG4105C6Y Udp-glucose 6-dehydrogenase BZ21_1383 ENOG4107104 thymidine kinase BZ21_1384 ENOG4108EKI Dehydrogenase BZ21_1385 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BZ21_1386 ENOG4107QSI ABC, transporter BZ21_1388 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ21_1389 ENOG4105C3U ABC transporter BZ21_1390 ENOG4108JQ7 (ABC) transporter BZ21_1394 ENOG4108T1M outer membrane protein x BZ21_1397 ENOG4105K9H YciI-like protein BZ21_1399 ENOG410822N TonB family BZ21_1400 ENOG4105NAU thioesterase Superfamily protein BZ21_1404 ENOG4105EIF outer membrane protein W BZ21_1408 ENOG4105DK0 Indole-3-glycerol phosphate synthase BZ21_1410 ENOG4105DDQ anthranilate synthase BZ21_1412 ENOG4105DB7 PHP domain protein BZ21_1413 ENOG4107RTD sua5 ycio yrdc ywlc family protein BZ21_1414 ENOG4105FE9 pseudouridine synthase BZ21_1415 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BZ21_1416 ENOG4105UBK short-chain dehydrogenase reductase BZ21_1417 ENOG4105ERU peptidase BZ21_1418 ENOG4105RKX Protein of unknown function (DUF2498) BZ21_142 ENOG4105CIN aminoacyl-histidine dipeptidase BZ21_1420 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ21_1421 ENOG4107R11 Transcriptional regulator BZ21_1423 ENOG4107QM5 aconitate hydratase BZ21_1424 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BZ21_1425 ENOG4105EYK Phosphatidylglycerophosphatase B BZ21_1426 ENOG4105Q4A inner membrane protein yciS BZ21_1427 ENOG4105CFV Tetratricopeptide repeat protein BZ21_1430 ENOG4108ZJT translation initiation factor, Sui1 BZ21_1431 ENOG41061RM osmotically inducible lipoprotein BZ21_1432 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ21_1434 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BZ21_1435 ENOG4105VCD cytoplasmic protein BZ21_1436 ENOG4105D22 carbon starvation protein BZ21_1438 ENOG4105CSP Major Facilitator Superfamily BZ21_1439 ENOG4105EXW epimerase dehydratase BZ21_1440 ENOG4105CSM endonuclease III BZ21_1442 ENOG4108UQQ Electron transport complex BZ21_1444 ENOG4105UEI Transcriptional Regulator AraC Family BZ21_1448 ENOG4105M9B inner membrane protein ydgK BZ21_1451 ENOG4108JJA ABC, transporter BZ21_1455 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator BZ21_1457 ENOG4105CNN ABC, transporter BZ21_1459 ENOG4105D9R oxidoreductase BZ21_1460 ENOG4105DHU Bile acid BZ21_1464 ENOG4105CI1 PTS System BZ21_1465 ENOG4105FDP GntR family transcriptional regulator BZ21_1466 ENOG4106J39 exported protein BZ21_1467 ENOG4105EIP mannose-6-phosphate isomerase BZ21_1468 ENOG4105C9Q fumarate hydratase class II BZ21_1470 ENOG4105D94 Major Facilitator Superfamily BZ21_1471 ENOG4106NZI LysR family Transcriptional regulator BZ21_1473 ENOG4105DAG ROK family BZ21_1474 ENOG4105KBG Protein of unknown function (DUF1161) BZ21_1476 ENOG4105EMU Dehydrogenase BZ21_1477 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BZ21_1478 ENOG4105C26 Dehydrogenase BZ21_1480 ENOG4105DWP Membrane BZ21_1481 ENOG4105C87 Aminotransferase class I and II BZ21_1482 ENOG4105DFD Na H antiporter BZ21_1483 ENOG41060NJ transcriptional regulator BZ21_1485 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ21_1486 ENOG4105CNN ABC, transporter BZ21_1487 ENOG4105C2J ABC transporter BZ21_1489 ENOG4107UWC ABC, transporter BZ21_1490 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ21_1492 ENOG4105FYV Amp nucleosidase BZ21_1497 ENOG4105C7K acetolactate synthase BZ21_1498 ENOG4105M71 acetolactate synthase 1 regulatory subunit BZ21_1499 ENOG4105PAD Hydrolase BZ21_1502 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ21_1503 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BZ21_1506 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ21_1507 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ21_1508 ENOG4105C5D exported protein BZ21_1509 ENOG4105D5Q Arginine ornithine antiporter BZ21_1511 ENOG4107EXC regulatoR BZ21_1512 ENOG4105JJR Histidine kinase BZ21_1513 ENOG4105CTD carboxy-peptidase BZ21_1516 ENOG4105DS1 cytochrome b561 BZ21_1518 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap BZ21_1521 ENOG4105CQ7 ATP-dependent helicase BZ21_1523 ENOG4105DKT Transcriptional regulator BZ21_1524 ENOG4105DEI Mannitol dehydrogenase BZ21_1525 ENOG4105WXT Conserved Protein BZ21_1526 ENOG410689M (LipO)protein BZ21_1527 ENOG4107H52 Dicarboxylate transport BZ21_1528 ENOG4105C5I Dehydrogenase BZ21_1529 ENOG41090X5 Heat shock protein hslJ BZ21_153 ENOG4105F2W methyltransferase BZ21_1531 ENOG4105KT7 mgtC SapB transporter BZ21_1533 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) BZ21_1539 ENOG4107QSI ABC, transporter BZ21_1540 ENOG4105KXI murein peptide amidase A BZ21_1541 ENOG4107S8C mandelate racemase muconate lactonizing BZ21_1542 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BZ21_1547 ENOG4105CM6 amino acid regulated cytosolic protein BZ21_1549 ENOG4105FM1 phage shock protein C BZ21_1550 ENOG4105YYT phage shock protein B BZ21_1551 ENOG41087YS Phage shock protein A BZ21_1552 ENOG4105E51 psp operon transcriptional activator BZ21_1553 ENOG4108HIY periplasmic BZ21_1554 ENOG4108I5W peptide transport system, permease protein BZ21_1555 ENOG4108EU3 peptide transport system, permease BZ21_1556 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein BZ21_1557 ENOG4108JQ2 peptide transport system atp-binding protein BZ21_1558 ENOG4105Q4T oxidoreductase BZ21_1560 ENOG4105DUX Transporter BZ21_1561 ENOG41069YE inner membrane protein yohC BZ21_1562 ENOG4108ZR5 Conserved Protein BZ21_1563 ENOG4108K3A Glutathione S-transferase BZ21_1567 ENOG410642K Lysozyme inhibitor BZ21_1569 ENOG4108XTF Outer Membrane Lipoprotein BZ21_1571 ENOG4107RGM aldo keto reductase BZ21_1572 ENOG4105XZD Fe-S protein BZ21_1573 ENOG4105DIJ Phosphoethanolamine transferase BZ21_1574 ENOG4108WUH Transcriptional regulator, TetR family BZ21_1575 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ21_1577 ENOG4108UYE Lactoylglutathione lyase BZ21_1579 ENOG4105M2J Glutaredoxin BZ21_158 ENOG4105DKQ ROK family BZ21_1581 ENOG4105K4H Nlp p60 protein BZ21_1582 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ21_1585 ENOG4105F52 Transcriptional regulator BZ21_1586 ENOG4105CZQ inner membrane transport protein YdhC BZ21_1587 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BZ21_1588 ENOG4108R6K riboflavin synthase, subunit alpha BZ21_159 ENOG4105EYH Exonuclease BZ21_1594 ENOG4105CA9 Pyruvate kinase BZ21_1595 ENOG4105KMX major outer membrane lipoprotein BZ21_1596 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BZ21_1599 ENOG4105JRK feS assembly protein SufD BZ21_160 ENOG4107RH8 nuclease SbcCD subunit D BZ21_1600 ENOG4105C3K feS assembly ATPase SufC BZ21_1601 ENOG4105DIW FeS assembly protein SUFB BZ21_1602 ENOG4108Z4V iron-sulfur cluster assembly BZ21_1603 ENOG4105KA0 thioesterase Superfamily protein BZ21_1604 ENOG4105CQB FAD linked oxidase domain protein BZ21_1605 ENOG4105IPI Membrane BZ21_1606 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BZ21_1608 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ21_161 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BZ21_1611 ENOG4108QBX (LipO)protein BZ21_1619 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) BZ21_162 ENOG4105BZU Histidine kinase BZ21_1620 ENOG4108V06 Glutathione peroxidase BZ21_1623 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BZ21_1630 ENOG41087WU BZ21_1634 ENOG4105DSE periplasmic solute binding protein BZ21_1635 ENOG4105DIK (ABC) transporter BZ21_1636 ENOG4105CC5 ABC transporter BZ21_1637 ENOG4105CC5 ABC transporter BZ21_1638 ENOG4105FGM Fructosamine kinase BZ21_1639 ENOG4107PN8 YfeABCD locus regulator BZ21_164 ENOG4105CWM branched-chain amino acid transport system II carrier protein BZ21_1640 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 BZ21_1641 ENOG4105M5J Cupin 2, conserved barrel domain protein BZ21_1643 ENOG4105CHR reductase BZ21_1644 ENOG41061NF Pectate lyase BZ21_1645 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BZ21_1646 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BZ21_1648 ENOG4105WEM extracellular solute-binding protein BZ21_1649 ENOG4108PU9 oligogalacturonate-specific porin BZ21_165 ENOG4105C85 amino acid BZ21_1650 ENOG4107K5X Membrane-bound metal-dependent hydrolase BZ21_1651 ENOG4108ETY sodium dicarboxylate symporter BZ21_1652 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ21_1654 ENOG4105CAZ oligogalacturonide lyase BZ21_1655 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ21_1656 ENOG4108VEV chaperone BZ21_1659 ENOG4108VEV chaperone BZ21_166 ENOG4107R28 alpha amylase, catalytic region BZ21_1660 ENOG4105H8W Fimbrial protein BZ21_1663 ENOG4105CN1 protease BZ21_1665 ENOG4108ZGC gaf domain protein BZ21_1666 ENOG4105H2K paraquat-inducible protein a BZ21_1667 ENOG4105DY2 Paraquat-inducible protein b BZ21_167 ENOG4105CHR reductase BZ21_1671 ENOG4105GQR Chaperone BZ21_1674 ENOG4105WT8 Protein of unknown function (DUF1480) BZ21_1681 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ21_1685 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ21_1686 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) BZ21_1687 ENOG4108VYJ response regulator receiver protein BZ21_1689 ENOG4105BZU Histidine kinase BZ21_169 ENOG4105D3R alkyl hydroperoxide reductase BZ21_1690 ENOG4105C8Q Methyl-accepting chemotaxis BZ21_1691 ENOG4105C8Q Methyl-accepting chemotaxis BZ21_1694 ENOG4108V3W Chemotaxis protein, CheW BZ21_1695 ENOG4105CBS Chea signal transduction histidine kinase BZ21_1696 ENOG4105ER2 Ompa motb domain protein BZ21_1697 ENOG4107RD7 Flagellar Motor Protein, MotA BZ21_1698 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region BZ21_17 ENOG4105C2J ABC transporter BZ21_1700 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BZ21_1701 ENOG4105KT7 mgtC SapB transporter BZ21_1702 ENOG4105C8Q Methyl-accepting chemotaxis BZ21_1704 ENOG4105VEQ Cold shock protein BZ21_1708 ENOG4105GSJ Inner membrane protein ylaC BZ21_1709 ENOG4108XM1 transcriptional regulator AsnC family BZ21_171 ENOG4108ZYK Acyl carrier protein phosphodiesterase BZ21_1711 ENOG41061EV selenium-binding protein YdfZ BZ21_1712 ENOG4105D6F Phosphatase BZ21_1714 ENOG4105KVH Transcriptional regulator BZ21_1715 ENOG4105ECR NmrA family BZ21_1716 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BZ21_1718 ENOG4106NDP Transcriptional regulator BZ21_1719 ENOG4108HMX isocitrate dehydrogenase (NADP) BZ21_1720 ENOG4108R99 pseudouridine synthase BZ21_1724 ENOG4107QTF adenylosuccinate lyase BZ21_1726 ENOG4105XJC Two component transcriptional regulator (Winged helix family BZ21_1728 ENOG4105EZE Cupin 4 family protein BZ21_1730 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BZ21_1732 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ21_1734 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ21_1735 ENOG4108JA2 transcriptioN-repair coupling factor BZ21_1736 ENOG4107MBR 17 kDa surface antigen BZ21_1739 ENOG4105CEP NADH dehydrogenase BZ21_174 ENOG4105VIE preprotein translocase, subunit YajC BZ21_1744 ENOG41090DQ Lipoprotein BZ21_1745 ENOG4105K59 histidine triad (HIT) protein BZ21_1746 ENOG4105F9E Shikimate 5-dehydrogenase BZ21_175 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ21_1753 ENOG4105ED4 portal protein BZ21_1757 ENOG4105CI1 PTS System BZ21_1758 ENOG4105F8V Hydrolase, tatD family BZ21_1759 ENOG4107QRG dna polymerase iii BZ21_176 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ21_1761 ENOG4105HHA aminodeoxychorismate lyase BZ21_1762 ENOG4105YAZ 4-amino-4-deoxychorismate lyase BZ21_1763 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ21_1765 ENOG4105CHR reductase BZ21_1766 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ21_1769 ENOG4105VGS 50s ribosomal protein l32 BZ21_1770 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BZ21_1772 ENOG4105EI2 Pseudouridine synthase BZ21_1774 ENOG4107QQB Ribonuclease E BZ21_1775 ENOG41067V3 Antibiotic biosynthesis monooxygenase BZ21_1778 ENOG4105PVA Biofilm formation regulatory protein BssS BZ21_1782 ENOG4105DSF transport protein BZ21_1785 ENOG4105D1S lipid A biosynthesis BZ21_1786 ENOG4105DUX Transporter BZ21_1787 ENOG4105NAC (LipO)protein BZ21_1788 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) BZ21_1789 ENOG4105DJ9 glucan biosynthesis protein BZ21_179 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BZ21_1790 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) BZ21_1794 ENOG4105VJY transcriptional regulator BZ21_1795 ENOG4107YC3 synthase BZ21_1796 ENOG4105ETT transcriptional Regulator, LysR family BZ21_1798 ENOG4105C54 Major Facilitator superfamily BZ21_18 ENOG4105CNN ABC, transporter BZ21_1800 ENOG4105CPC Aldo Keto reductase BZ21_1801 ENOG4108Y1S CRISPR-associated protein, Csy4 family BZ21_1802 ENOG4105M6W Crispr-associated protein, Csy3 family BZ21_1803 ENOG4105DZX CRISPR-associated protein, Csy2 family BZ21_1804 ENOG4105ENG CRISPR-associated protein, Csy1 family BZ21_1805 ENOG4107IIZ CRISPR-associated helicase, Cas3 BZ21_1806 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) BZ21_1808 ENOG4105CUY Mechanosensitive ion channel BZ21_1812 ENOG4105HY2 Glycosidase related protein BZ21_1813 ENOG4105DRS transport system, permease BZ21_1816 ENOG4105ETE Transcriptional regulator (LacI family BZ21_1818 ENOG4108IJ9 (ABC) transporter BZ21_182 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BZ21_1821 ENOG4105CKT filamentous hemagglutinin BZ21_1824 ENOG4105CKT filamentous hemagglutinin BZ21_1825 ENOG4105D5K Hemolysin activator protein BZ21_1826 ENOG4105E3J oxidoreductase BZ21_1827 ENOG4105DVW rieske (2Fe-2S) BZ21_1828 ENOG4105C94 Transporter BZ21_1829 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BZ21_183 ENOG4108ZAI phosphatidylglycerophosphatase a BZ21_1830 ENOG4105EJC lysr family transcriptional regulator BZ21_1831 ENOG4105FKQ transcriptional regulator BZ21_1832 ENOG4105CNN ABC, transporter BZ21_1833 ENOG4105C2J ABC transporter BZ21_1834 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ21_1835 ENOG4105CPQ Dehydrogenase BZ21_1839 ENOG4108T1M outer membrane protein x BZ21_1845 ENOG4107R0W ABC transporter BZ21_1846 ENOG4105E5Q amino acid AbC transporter BZ21_1847 ENOG4105CDA abc transporter atp-binding protein BZ21_1848 ENOG4107SDU Methyl-accepting chemotaxis BZ21_185 ENOG4105CTB Polyprenyl synthetase BZ21_1850 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction BZ21_1851 ENOG4108MTB glycosyl transferase family BZ21_1852 ENOG4105CEY Amp-dependent synthetase and ligase BZ21_1854 ENOG4108IPT Naphthoate synthase BZ21_1857 ENOG4105E4F Isochorismate synthase BZ21_1859 ENOG4105TNS Conserved Protein BZ21_1861 ENOG4105C01 Dihydroxy-acid dehydratase BZ21_1864 ENOG4105C5I Dehydrogenase BZ21_1865 ENOG4105K2J Transcriptional regulator BZ21_1866 ENOG4105F32 YngK protein BZ21_1867 ENOG4105CHR reductase BZ21_1868 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ21_1869 ENOG4108R66 Conserved Protein BZ21_1872 ENOG4105C8S subunit m BZ21_1873 ENOG4105D65 subunit l BZ21_1875 ENOG4107UFS subunit j BZ21_1878 ENOG4108IEH NADH dehydrogenase subunit g BZ21_1879 ENOG4107QIZ NADH dehydrogenase BZ21_188 ENOG4107S0N DJ-1 family BZ21_1880 ENOG4105GKE subunit e BZ21_1882 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BZ21_1884 ENOG4107NQ8 LysR family Transcriptional regulator BZ21_1885 ENOG4105CHM Aminotransferase BZ21_1888 ENOG4107QWE )-transporter BZ21_1889 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 BZ21_189 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BZ21_1893 ENOG4105C6K Malic enzyme BZ21_1894 ENOG4107P2S Transcriptional regulator BZ21_1897 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BZ21_1898 ENOG4105PTV Nudix Hydrolase BZ21_1899 ENOG4108RE9 Phosphodiesterase BZ21_19 ENOG4108HHA Transketolase BZ21_1901 ENOG4105ECP epimerase BZ21_1902 ENOG4108JEH abc transporter atp-binding protein BZ21_1903 ENOG4106YG3 ABC transporter BZ21_1904 ENOG4105DSP amino acid AbC transporter BZ21_1907 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BZ21_1908 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BZ21_1909 ENOG4105E96 Colicin v production protein BZ21_191 ENOG4107RDB Major Facilitator BZ21_1910 ENOG4108S3P Sporulation domain protein BZ21_1911 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BZ21_1913 ENOG4105DQR SNARE associated Golgi BZ21_1915 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ21_1918 ENOG410631K Membrane BZ21_1919 ENOG4106WZ1 flagella biosynthesis regulator BZ21_1922 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ21_1924 ENOG4105MH2 YfcL protein BZ21_1925 ENOG4108BPE -transporting atpase BZ21_1926 ENOG4105EJ9 Membrane BZ21_1929 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BZ21_193 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BZ21_1931 ENOG4108BY2 phosphohistidine phosphatase BZ21_1934 ENOG4105KZW UPF0381 protein BZ21_1935 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BZ21_1936 ENOG410903C (LipO)protein BZ21_1937 ENOG4105KWW Biogenesis protein BZ21_1938 ENOG4105KWW Biogenesis protein BZ21_1939 ENOG4107QX9 Thiol disulfide interChange protein BZ21_194 ENOG4105CCU oxidase (Subunit III) BZ21_1940 ENOG4105DA4 cytochrome c-type biogenesis protein BZ21_1942 ENOG4105X3C heme exporter protein BZ21_1943 ENOG41060IM Heme exporter protein BZ21_1944 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BZ21_1948 ENOG4108V0P LemA family BZ21_195 ENOG4105BZ9 Cytochrome C oxidase, subunit I BZ21_1950 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BZ21_1956 ENOG4105CS6 Rhs element vgr protein BZ21_196 ENOG4105E2S oxidase) subunit II BZ21_1965 ENOG4105CW0 outer membrane usher protein BZ21_1966 ENOG4105GQR Chaperone BZ21_1968 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ21_197 ENOG4108NFH Sugar hydrolase BZ21_1978 ENOG4105CVE Lytic murein transglycosylase BZ21_198 ENOG4105EYM Major Facilitator superfamily BZ21_1984 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ21_1986 ENOG4107QY8 reductase BZ21_1987 ENOG4105QAX Iron-sulfur BZ21_1988 ENOG4107KGK dmso reductase anchor subunit BZ21_1989 ENOG4108NEM leader-binding protein dmsD BZ21_199 ENOG4105IEY (LipO)protein BZ21_1991 ENOG4107Y60 (LipO)protein BZ21_1993 ENOG4106B0W Curli production assembly transport component CsgG BZ21_1995 ENOG4108VKM cytochrome b561 BZ21_1996 ENOG4105CHM Aminotransferase BZ21_1997 ENOG41072TH Protein of unknown function (DUF1479) BZ21_2 ENOG4105F5R ABC transporter BZ21_20 ENOG4108IUS Transketolase BZ21_200 ENOG4105M85 Bola protein BZ21_2000 ENOG4105C5Q Transcriptional regulator BZ21_2001 ENOG4105CPC Aldo Keto reductase BZ21_2004 ENOG4105D9N nucleoside BZ21_2015 ENOG4105VRT cytoplasmic protein BZ21_2018 ENOG4105EXN Sulfate transport protein CysZ BZ21_2019 ENOG4105C6T cysteine synthase BZ21_2020 ENOG4105KZ7 phosphocarrier protein hpr BZ21_2022 ENOG4105C5Y PTS System BZ21_2023 ENOG4105E0F Histidine kinase BZ21_2024 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ21_2025 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ21_2028 ENOG4105E1V na solute symporter BZ21_2030 ENOG4107RAQ aminopeptidase BZ21_2031 ENOG4105C87 Aminotransferase class I and II BZ21_2033 ENOG41062D9 Histidine kinase BZ21_2034 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ21_2036 ENOG4105C6T cysteine synthase BZ21_2038 ENOG4105ECW sulfate abc transporter BZ21_2039 ENOG4108I5D sulfate abc transporter BZ21_2040 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein BZ21_2042 ENOG4105QEK Transcriptional regulator BZ21_2043 ENOG4108R66 Conserved Protein BZ21_2048 ENOG4105EZR dyp-type peroxidase family protein BZ21_2049 ENOG4105E7K (LipO)protein BZ21_205 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BZ21_2050 ENOG4105H4F exported protein BZ21_206 ENOG4105K70 DNA-binding protein BZ21_2061 ENOG4105C6K Malic enzyme BZ21_2063 ENOG4105CUW cytochrome C-TYPE protein BZ21_2064 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) BZ21_2066 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase BZ21_2067 ENOG4108ZNS ferredoxin-type protein NapF BZ21_2068 ENOG4105WH1 Two component transcriptional regulator luxr family BZ21_207 ENOG4105EIN peptidylprolyl cis-trans isomerase BZ21_2070 ENOG4105BZS acriflavin resistance protein BZ21_2072 ENOG4105S2T inner membrane protein YbcI BZ21_2073 ENOG4105C4X radical SAM domain protein BZ21_2074 ENOG4105ENH Sulfatase BZ21_2075 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ21_2076 ENOG4107Z33 ABC transporter, permease BZ21_2077 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC BZ21_2079 ENOG4105KUZ arsenate reductase BZ21_208 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BZ21_2085 ENOG4105CGZ zinc metallopeptidase BZ21_2087 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ21_2089 ENOG4105RH4 Glycine cleavage system transcriptional repressor BZ21_209 ENOG4108TGP Thioesterase superfamily protein BZ21_2090 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BZ21_2093 ENOG4105C02 permease BZ21_2094 ENOG4105ERG peptidase m48, ste24p BZ21_2095 ENOG4105K89 arsenate reductase BZ21_2097 ENOG4105C2W permease BZ21_21 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BZ21_2100 ENOG4108V3E phosphoribosylglycinamide formyltransferase BZ21_2101 ENOG4108MK9 spermidine N(1)-acetyltransferase BZ21_2102 ENOG4108C80 FliB family BZ21_2104 ENOG4105E2Z phosphate ABC transporter (Permease BZ21_2105 ENOG4105C8U phosphate abc transporter BZ21_2106 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BZ21_2107 ENOG4105C9X ppx gppa phosphatase BZ21_2108 ENOG4105CJW magnesium transporter BZ21_2109 ENOG4105R8A Heat shock protein BZ21_211 ENOG4108NFA extracellular solute-binding protein BZ21_2111 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BZ21_2112 ENOG4105F38 ABC transporter, permease BZ21_2114 ENOG4108JPW Aminotransferase BZ21_2116 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ21_2121 ENOG4105EB3 Histidine kinase BZ21_2122 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ21_2123 ENOG4105KWI UPF0339 protein BZ21_2124 ENOG4105CFP Peptidase U32 BZ21_2126 ENOG4108ZGU inhibitor of vertebrate lysozyme BZ21_2128 ENOG4105DWF phosphomethylpyrimidine kinase BZ21_213 ENOG4105C6T cysteine synthase BZ21_2135 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ21_2137 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BZ21_2139 ENOG4105VPD cellular component movement BZ21_214 ENOG4108XM1 transcriptional regulator AsnC family BZ21_2142 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ21_2143 ENOG4105N21 Membrane BZ21_215 ENOG4105BZ1 (ABC) transporter BZ21_2151 ENOG4108MGN ATP-binding component of a transport system BZ21_2152 ENOG4108MGN ATP-binding component of a transport system BZ21_2153 ENOG4105YYA enhanced serine sensitivity protein SseB BZ21_2155 ENOG4105WVQ Fe-S assembly protein IscX BZ21_2156 ENOG4108ZIT Ferredoxin, 2FE-2S BZ21_216 ENOG4105BZ1 (ABC) transporter BZ21_2160 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BZ21_2161 ENOG4105C3J Cysteine desulfurase BZ21_2165 ENOG4105D7X high-affinity nickel-transporter BZ21_2166 ENOG41065CD Exported protein BZ21_2167 ENOG4105D8G Major Facilitator superfamily BZ21_2168 ENOG4108MN2 Stationary phase inducible protein CsiE BZ21_217 ENOG4108YZA Nitrogen regulatory protein pii BZ21_2171 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ21_2172 ENOG4108M21 BZ21_2173 ENOG4108YZA Nitrogen regulatory protein pii BZ21_2174 ENOG4105C4K Nad synthetase BZ21_2175 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ21_2176 ENOG4108SKK alpha helix protein BZ21_2177 ENOG4107WP9 Histidine kinase BZ21_218 ENOG4105BZU Histidine kinase BZ21_2182 ENOG4108Z6B deaminase BZ21_2183 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB BZ21_2185 ENOG4106G6Q Transcriptional regulator BZ21_2186 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BZ21_219 ENOG4105C29 acyl-CoA thioesterase BZ21_2192 ENOG4105C3F Signal peptidase i BZ21_2195 ENOG4105WMJ Positive regulator of sigma E, RseC MucC BZ21_2196 ENOG4105VQK sigma E regulatory protein, MucB RseB BZ21_2197 ENOG41069PW sigma-e factor negative regulatory protein BZ21_2199 ENOG4108IYU L-aspartate oxidase BZ21_220 ENOG4108MNP Glycoprotein polysaccharide metabolism BZ21_2201 ENOG4105C1J atp-dependent rna helicase BZ21_221 ENOG41080UX Methyltransferase BZ21_2212 ENOG4107R7A Allophanate hydrolase subunit 2 BZ21_2213 ENOG4105P4J Allophanate hydrolase, subunit 1 BZ21_2215 ENOG4107QNR UPF0135 protein BZ21_2216 ENOG4107RF4 Phosphodiesterase BZ21_2217 ENOG4105CVP deoxyribo-dipyrimidine photolyase BZ21_2218 ENOG4107SEY Conserved Protein BZ21_2219 ENOG4105XIQ Protein of unknown function (DUF2517) BZ21_222 ENOG4105KF5 hemolysin expression-modulating protein BZ21_2223 ENOG4105C08 Histidine kinase BZ21_2224 ENOG4105EEX Two component transcriptional regulator (Winged helix family BZ21_2228 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 BZ21_223 ENOG4108UKR Biofilm formation regulator YbaJ BZ21_2233 ENOG4105EZV Transcriptional regulator BZ21_2234 ENOG4105VCP PTS System BZ21_2235 ENOG4105CK1 PTS System BZ21_2236 ENOG4105VZJ PTS System BZ21_2238 ENOG41086WQ Protein CrcB homolog BZ21_2239 ENOG4107SVH Potassium channel protein BZ21_2240 ENOG4105XXV Acid-resistance protein BZ21_2244 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) BZ21_225 ENOG4105YK5 50S ribosomal protein L36 BZ21_2251 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) BZ21_2252 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) BZ21_2253 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ21_2254 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ21_2255 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BZ21_2256 ENOG4105VEQ Cold shock protein BZ21_2258 ENOG4108SAJ Protein of unknown function (DUF1198) BZ21_2259 ENOG4108WMJ Protein of unknown function (DUF2002) BZ21_2264 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ21_2265 ENOG4108IJ7 Glycine betaine BZ21_2266 ENOG4108HQS Glycine betaine BZ21_2267 ENOG4105GIJ Glycine betaine BZ21_2269 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BZ21_227 ENOG4105BZS acriflavin resistance protein BZ21_2271 ENOG4108JDX DNA polymerase iii, epsilon subunit BZ21_2273 ENOG4105D1A Methyltransferase BZ21_2275 ENOG4105E9H Lytic Murein transglycosylase BZ21_2278 ENOG4105CV8 reductase BZ21_228 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ21_2285 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BZ21_2287 ENOG4108UMI ABC transporter, permease BZ21_2288 ENOG4105D01 (LipO)protein BZ21_2289 ENOG4108R8X outer membrane lipoprotein BZ21_229 ENOG4108IG5 Transcriptional regulator BZ21_2290 ENOG4108R96 Methyltransferase, YaeB family BZ21_2292 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BZ21_2293 ENOG4108YZN class I peptide chain release factor BZ21_2294 ENOG4108VWS Yaeq family BZ21_2296 ENOG4105M1T rho-binding antiterminator BZ21_2299 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BZ21_230 ENOG41090EX DsrE family BZ21_2301 ENOG4105C0B DNA polymerase III (alpha subunit) BZ21_2303 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BZ21_2307 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) BZ21_2309 ENOG4105DZP Membrane-associated zinc metalloprotease BZ21_231 ENOG4105EGS Mechanosensitive ion channel BZ21_2310 ENOG4105KNE Phosphatidate cytidylyltransferase BZ21_2311 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BZ21_2317 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ21_2321 ENOG4105QDK Flavodoxin BZ21_2322 ENOG4105DR9 pseudouridine synthase BZ21_2323 ENOG4105WP7 tRNA pseudouridine synthase C BZ21_2327 ENOG4105EWT decarboxylase family BZ21_233 ENOG4105WD1 Membrane BZ21_2330 ENOG4105M08 Membrane BZ21_2331 ENOG4105ETT transcriptional Regulator, LysR family BZ21_2333 ENOG4105C9B Cysteine desulfurase BZ21_2334 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BZ21_2335 ENOG4105CUZ uba thif-type nad fad binding protein BZ21_2336 ENOG4105CA3 membrane-bound lytic murein transglycosylase BZ21_2340 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ21_2342 ENOG4107QYX exodeoxyribonuclease v alpha BZ21_2343 ENOG4107QKA exodeoxyribonuclease V beta BZ21_2344 ENOG4107QXK peptidase BZ21_2345 ENOG4105DSY exodeoxyribonuclease V, gamma BZ21_235 ENOG4107QMP dna polymerase iii subunits gamma and tau BZ21_2353 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BZ21_2356 ENOG4105CPC Aldo Keto reductase BZ21_2362 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BZ21_2363 ENOG41060NJ transcriptional regulator BZ21_2364 ENOG4105F27 Major Facilitator BZ21_2365 ENOG4105RQF LysR family Transcriptional regulator BZ21_2366 ENOG4105EJC lysr family transcriptional regulator BZ21_2368 ENOG4105C8Q Methyl-accepting chemotaxis BZ21_2381 ENOG4105D7Q type ii secretion system BZ21_2382 ENOG4107QHF type ii secretion system protein e BZ21_2386 ENOG4107B2H carbonic anhydrase BZ21_2391 ENOG4105CBG Sulfatase BZ21_2392 ENOG4105E98 transcriptional regulator DeoR family BZ21_2393 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of BZ21_2394 ENOG4105E70 isomerase BZ21_2395 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB BZ21_2396 ENOG4105ETZ PTS System BZ21_2397 ENOG4105F3R pts system mannose fructose sorbose family iid BZ21_2398 ENOG4108YTN IIa component BZ21_2399 ENOG4105CE4 GlcNAc 6-P deacetylase BZ21_2400 ENOG4105CHR reductase BZ21_2402 ENOG4105C4X radical SAM domain protein BZ21_2403 ENOG4105ENH Sulfatase BZ21_2405 ENOG4105D2N Aldolase BZ21_2408 ENOG4105ETE Transcriptional regulator (LacI family BZ21_2409 ENOG4105DPW Major facilitator superfamily MFS_1 BZ21_2411 ENOG4105ETE Transcriptional regulator (LacI family BZ21_2413 ENOG4105CI1 PTS System BZ21_2414 ENOG4105C4C beta-galactosidase BZ21_2416 ENOG4105EG2 ABC transporter, permease BZ21_2418 ENOG4107FKK extracellular solute-binding protein family 1 BZ21_242 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BZ21_2421 ENOG4105CNN ABC, transporter BZ21_2422 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ21_2424 ENOG4108UY0 (LipO)protein BZ21_2425 ENOG4105NTW Transcriptional regulator BZ21_243 ENOG4105FAW cDP-glucose 4,6-dehydratase BZ21_244 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ21_2442 ENOG4105WJ3 XRE family Transcriptional regulator BZ21_2443 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation BZ21_2447 ENOG4105DFP Integrase BZ21_245 ENOG4108SMP Nad-dependent epimerase dehydratase BZ21_2451 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BZ21_2452 ENOG4105T95 Thiol disulfide interChange protein BZ21_2453 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ21_2454 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) BZ21_2455 ENOG4105CT7 inner membrane cred family protein BZ21_2456 ENOG4105EB3 Histidine kinase BZ21_2457 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ21_2458 ENOG4105Y75 tpr repeat protein BZ21_2461 ENOG4108UT2 hemolysin iii BZ21_2468 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ21_2469 ENOG4105D0A hydroxylase BZ21_2470 ENOG4107RAQ aminopeptidase BZ21_2473 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BZ21_2474 ENOG4108JQ1 Dehydrogenase BZ21_2475 ENOG4105E66 phosphoriboisomerase A BZ21_2477 ENOG4105MPN Membrane BZ21_2479 ENOG4105D64 Mechanosensitive ion channel BZ21_2480 ENOG4105D2N Aldolase BZ21_2483 ENOG4105CV1 Transketolase (EC 2.2.1.1) BZ21_2484 ENOG4108K0D peptidase, M48 BZ21_2486 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BZ21_249 ENOG4107Y2G Glycosyl transferase (Group 1 BZ21_2490 ENOG4105RWS endonuclease I BZ21_2491 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BZ21_2492 ENOG4105D7Z glutathione synthase BZ21_2495 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) BZ21_2497 ENOG4105CZX twitching motility protein BZ21_2498 ENOG4105DFA alanine racemase domain protein BZ21_2499 ENOG4105II7 pyrroline-5-carboxylate reductase BZ21_2500 ENOG4108VIA integral membrane protein BZ21_2502 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BZ21_2503 ENOG4105CSA Coproporphyrinogen iii oxidase BZ21_2504 ENOG4105EUK rtx toxin RtxA BZ21_2505 ENOG4105K33 Periplasmic Protein BZ21_2506 ENOG4105CSV Glutaminase BZ21_2507 ENOG41090ED Protein with unknown function (DUF469) BZ21_2509 ENOG4105CEN a g-specific adenine glycosylase BZ21_2514 ENOG4105CNN ABC, transporter BZ21_2515 ENOG4105C2J ABC transporter BZ21_2516 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ21_2517 ENOG4105CXN decarboxylase BZ21_252 ENOG4108I2E Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) BZ21_2525 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ21_2527 ENOG4105CDV Ompa motb domain protein BZ21_2545 ENOG4105DUU IucA IucC family protein BZ21_2546 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ21_2548 ENOG4105CT4 transporter BZ21_2550 ENOG4105ETE Transcriptional regulator (LacI family BZ21_2551 ENOG4105C8P )-transporter BZ21_2552 ENOG41062WK cellular response to acidity BZ21_2557 ENOG4105CNA YD repeat protein BZ21_2562 ENOG4105CNA YD repeat protein BZ21_2564 ENOG4105CS6 Rhs element vgr protein BZ21_2567 ENOG4107EFN gluconate transport system permease 3 BZ21_257 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BZ21_2571 ENOG4105BZ1 (ABC) transporter BZ21_2577 ENOG4105C0W non-ribosomal peptide synthetase BZ21_2578 ENOG4105C0W non-ribosomal peptide synthetase BZ21_2579 ENOG4107ZSV Receptor BZ21_2580 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BZ21_2581 ENOG4105CFC Transporter BZ21_2582 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway BZ21_2588 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ21_2589 ENOG4105BZU Histidine kinase BZ21_259 ENOG4108QY5 Ferric enterobactin transport protein BZ21_2591 ENOG4105DQ6 Transposase BZ21_2593 ENOG4108XTF Outer Membrane Lipoprotein BZ21_2598 ENOG4107RD7 Flagellar Motor Protein, MotA BZ21_260 ENOG4107RE1 Inosine-guanosine kinase BZ21_2604 ENOG410804A Flagellar hook-associated 2 domain-containing protein BZ21_2605 ENOG4105I03 Flagellin BZ21_2606 ENOG4105I03 Flagellin BZ21_2607 ENOG4108M3R transcriptional activator CadC BZ21_261 ENOG4105CKD glutathione-regulated potassium-efflux system protein BZ21_2611 ENOG4105E1Q flagellar hook-associated protein BZ21_2615 ENOG4105CGA flagellar basal-body rod protein FlgG BZ21_2616 ENOG4108KPB Flagellar basal-body rod protein FlgF BZ21_2617 ENOG4105BZE flagellar hook protein, FlgE BZ21_2618 ENOG4105W00 Flagellar hook capping protein BZ21_2619 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ21_262 ENOG4105EU0 Major facilitator Superfamily BZ21_2620 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ21_2621 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA BZ21_2625 ENOG4108JIR Flagellum-specific ATP synthase BZ21_2628 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ21_263 ENOG4105CGH 5'-nucleotidase BZ21_2630 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ21_2632 ENOG4105DD5 Flagellar motor switch protein BZ21_2633 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ21_2634 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ21_2635 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ21_2636 ENOG4105D00 flagellar biosynthetic protein flhB BZ21_2640 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein BZ21_2642 ENOG4106P2F Pfam:Pili_assembly_C BZ21_2643 ENOG4106PG1 outer membrane usher protein BZ21_2645 ENOG4105E03 chitinase BZ21_2646 ENOG4108M1A Chitin-binding protein BZ21_266 ENOG4108Z66 YbaK ebsC protein BZ21_2662 ENOG4108ZZF transport protein (ExbD) BZ21_2664 ENOG4105CWK Biopolymer transport protein, ExbB BZ21_2665 ENOG4105C28 cystathionine BZ21_2666 ENOG4108K81 inner membrane protein YghB BZ21_2667 ENOG4105CF7 AraC family transcriptional regulator BZ21_2668 ENOG4108I6A alcohol dehydrogenase BZ21_2669 ENOG4105CV8 reductase BZ21_267 ENOG4105MBR gumn family BZ21_2671 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) BZ21_2672 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase BZ21_2673 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ21_2674 ENOG4105NF4 modulator of drug activity BZ21_2675 ENOG4105CR8 Transcriptional regulator BZ21_2676 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ21_2677 ENOG4105IPS esterase BZ21_2678 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BZ21_2679 ENOG4108SX3 cytoplasmic protein BZ21_268 ENOG4105C59 p-type ATPase BZ21_2680 ENOG41087AY ADP-Ribose pyrophosphatase BZ21_2681 ENOG4105DFG type I secretion outer membrane protein BZ21_2684 ENOG4106032 Glutathionylspermidine synthase BZ21_2685 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BZ21_2687 ENOG4105W0Z cytoplasmic protein BZ21_2688 ENOG4105DVH amino acid BZ21_269 ENOG4108Z6Z Transcriptional regulator BZ21_2691 ENOG4105I7R Adenylate cyclase BZ21_2692 ENOG4106MWK domain protein BZ21_2695 ENOG4107ZVW dihydroneopterin aldolase BZ21_2698 ENOG4105VCC 30S ribosomal protein S21 BZ21_2699 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BZ21_270 ENOG4105G5H Membrane BZ21_2700 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ21_2707 ENOG4108X9F tail fiber protein BZ21_271 ENOG4107QX8 SPFH domain, Band 7 family protein BZ21_272 ENOG4107QR8 Thioredoxin BZ21_2725 ENOG4105ED4 portal protein BZ21_273 ENOG4105E1F short-chain dehydrogenase reductase BZ21_2733 ENOG4105MEH BZ21_2736 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ21_274 ENOG4108UJV acyl-CoA thioesterase i BZ21_2749 ENOG4105KME endoribonuclease L-psp BZ21_275 ENOG4108I0Y (ABC) transporter BZ21_2753 ENOG4105CHM Aminotransferase BZ21_2756 ENOG4105J12 Multidrug resistance protein mdtN BZ21_2757 ENOG4108MI0 Resistance protein BZ21_2759 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ21_276 ENOG4105CV6 ABC transporter, permease BZ21_2761 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BZ21_2763 ENOG4108IJG ABC transporter substrate-binding protein BZ21_2764 ENOG4107KJX Transcriptional regulator BZ21_2765 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 BZ21_277 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BZ21_2770 ENOG4105CKT filamentous hemagglutinin BZ21_2779 ENOG4105CKT filamentous hemagglutinin BZ21_278 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BZ21_2781 ENOG4105CKT filamentous hemagglutinin BZ21_2783 ENOG4105CKT filamentous hemagglutinin BZ21_2784 ENOG4105D5K Hemolysin activator protein BZ21_2785 ENOG4108M24 von Willebrand factor, type A BZ21_2787 ENOG4108M24 von Willebrand factor, type A BZ21_2788 ENOG4108M24 von Willebrand factor, type A BZ21_2791 ENOG4108YK4 Acid-resistance membrane protein BZ21_2792 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ21_2795 ENOG4108VKG metal-dependent hydrolase BZ21_2796 ENOG4105EE0 oxidoreductase BZ21_2798 ENOG4105P66 Membrane BZ21_2799 ENOG4105CTX dehydratase BZ21_280 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ21_2800 ENOG4107QZW Altronate oxidoreductase BZ21_2802 ENOG4105DPW Major facilitator superfamily MFS_1 BZ21_2805 ENOG4106W5V Membrane BZ21_2808 ENOG4105NE1 Conserved Protein BZ21_2809 ENOG41090KG Inner membrane protein YqjE BZ21_2811 ENOG4108VBZ doxx family BZ21_2814 ENOG4108VBZ doxx family BZ21_2815 ENOG4105CHF Glutathione S-transferase BZ21_2816 ENOG4105CWB LysR family transcriptional Regulator BZ21_2817 ENOG4108CNN domain protein BZ21_2818 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BZ21_282 ENOG4105WQ3 Rna-binding protein BZ21_2822 ENOG4105W4M Transport-associated protein BZ21_2824 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BZ21_2825 ENOG4105BZU Histidine kinase BZ21_2827 ENOG4105N5T Radical SAM Protein BZ21_2828 ENOG4105CBC glutamate synthase BZ21_2829 ENOG4105BZ8 glutamate synthase BZ21_2831 ENOG4105KB2 stringent starvation protein b BZ21_2832 ENOG4107MKT Stringent starvation protein a BZ21_2835 ENOG4105D6Z AFG1 family ATPase BZ21_2836 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III BZ21_2837 ENOG4105C0H protease BZ21_2838 ENOG4105C0H protease BZ21_2840 ENOG4105VFK BolA family BZ21_2841 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane BZ21_2842 ENOG4105E3I toluene tolerance BZ21_2843 ENOG4107PE3 Mammalian cell entry related domain protein BZ21_2844 ENOG4105CY3 ABC transporter, permease BZ21_2845 ENOG4105DHJ ABC, transporter BZ21_2846 ENOG4105FEU K -dependent Na -Ca exchanger BZ21_2847 ENOG4105C2X Arabinose 5-phosphate isomerase BZ21_2848 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BZ21_2849 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) BZ21_2850 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BZ21_2851 ENOG4108IUZ ABC transporter BZ21_2852 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ21_2853 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BZ21_2854 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BZ21_2856 ENOG41080Z8 PHOSPHOCARRIER protein BZ21_2859 ENOG4105KME endoribonuclease L-psp BZ21_2861 ENOG4105D4X repressor BZ21_2862 ENOG4105C5Y PTS System BZ21_2863 ENOG4105CG3 alpha amylase, catalytic region BZ21_2865 ENOG4105NXH GreA GreB family elongation factor BZ21_2866 ENOG4108XVM Cytochrome b(562) BZ21_2868 ENOG4105CMS peptidase U62, modulator of DNA gyrase BZ21_2870 ENOG4105UNR (Barnase) inhibitor BZ21_2876 ENOG4105CR8 Transcriptional regulator BZ21_2885 ENOG4105D1U peptidase U62 modulator of DNA gyrase BZ21_2887 ENOG4105QD6 exported protein BZ21_2888 ENOG4105C03 ribonuclease BZ21_289 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase BZ21_2890 ENOG4105VQ7 Rod shape-determining protein MreD BZ21_2891 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BZ21_2892 ENOG4105DFF Rod shape-determining protein mreb BZ21_2893 ENOG41062P1 Diguanylate cyclase phosphodiesterase BZ21_2894 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family BZ21_2898 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BZ21_2899 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BZ21_29 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BZ21_290 ENOG4108HPI phosphatidate Cytidylyltransferase BZ21_2901 ENOG4105RG0 Membrane BZ21_2902 ENOG4108IA2 Sodium pantothenate symporter BZ21_2904 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ21_2905 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BZ21_2908 ENOG4105CSH Transporter BZ21_2909 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BZ21_2912 ENOG4108XTF Outer Membrane Lipoprotein BZ21_2913 ENOG4105VEQ Cold shock protein BZ21_2914 ENOG4105VEQ Cold shock protein BZ21_2915 ENOG4105VEQ Cold shock protein BZ21_2918 ENOG4105CYM Glutathione S-transferase BZ21_2919 ENOG4105C2X Arabinose 5-phosphate isomerase BZ21_292 ENOG4105E8V Alpha Beta Hydrolase Fold protein BZ21_2920 ENOG4105EF1 ribulokinase BZ21_2922 ENOG4105CNN ABC, transporter BZ21_2923 ENOG4105C2J ABC transporter BZ21_2925 ENOG4105D1S lipid A biosynthesis BZ21_2927 ENOG4105EEQ Na H antiporter BZ21_2928 ENOG4105C7N Xanthine uracil vitamin C permease BZ21_293 ENOG41077RS Phosphatase BZ21_2931 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BZ21_2933 ENOG4105GVF (ABC) transporter BZ21_2935 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ21_2936 ENOG4108RVA ribokinase BZ21_2937 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BZ21_2939 ENOG4107TYG Oxidoreductase domain-containing protein BZ21_2941 ENOG4105CS6 Rhs element vgr protein BZ21_2943 ENOG4105CNA YD repeat protein BZ21_2945 ENOG4105CS6 Rhs element vgr protein BZ21_2951 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ21_2961 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ21_2963 ENOG4107W52 maltose operon periplasmic protein BZ21_2967 ENOG4107FKK extracellular solute-binding protein family 1 BZ21_2968 ENOG4105D56 permease protein BZ21_2969 ENOG4105EG2 ABC transporter, permease BZ21_2972 ENOG4105CFH Aspartokinase BZ21_2975 ENOG4105C3R Methionine synthase BZ21_2976 ENOG41069M3 Transcriptional regulator BZ21_2978 ENOG4108I9X Isocitrate lyase BZ21_2979 ENOG4107QP3 malate synthase g BZ21_298 ENOG4105EQ2 LysR family Transcriptional regulator BZ21_299 ENOG4107SET aldo keto reductase BZ21_2991 ENOG4108Z0R Transferase BZ21_2994 ENOG4108WI1 Dna topoisomerase BZ21_2996 ENOG4105C79 DNA protecting protein DprA BZ21_3 ENOG4105CNN ABC, transporter BZ21_3000 ENOG4105C1A potassium transporter peripheral membrane BZ21_3002 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system BZ21_3003 ENOG4105W1Y Transcriptional regulator BZ21_3006 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BZ21_3009 ENOG41067V7 50S ribosomal protein L36 BZ21_3010 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BZ21_3012 ENOG4105VPB 50S ribosomal protein L30 BZ21_302 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ21_3021 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BZ21_3023 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BZ21_3024 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BZ21_3026 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BZ21_3036 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BZ21_3041 ENOG4105WWK YheO domain protein BZ21_3042 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ21_3044 ENOG4108YZY peptidylprolyl cis-trans isomerase BZ21_3045 ENOG4105VKU nucleicacid-binding protein BZ21_3048 ENOG4105C5H ABC transporter BZ21_3049 ENOG4105K64 Glycosyl transferase, family 2 BZ21_305 ENOG4105FE9 pseudouridine synthase BZ21_3051 ENOG4105E2B Taurine dioxygenase BZ21_3052 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ21_3054 ENOG4106FTQ Taurine ABC transporter, periplasmic BZ21_3056 ENOG4105DNZ Alpha Beta Hydrolase BZ21_3058 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) BZ21_306 ENOG4105EZE Cupin 4 family protein BZ21_3060 ENOG4108UKZ OsmC family BZ21_3062 ENOG410613R integral membrane protein, YccS YhfK family BZ21_3063 ENOG4105C8Y Acetylornithine aminotransferase BZ21_3065 ENOG4105D7A ATP-binding protein BZ21_3066 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ21_3068 ENOG4105F8D glycoside hydrolase family 4 BZ21_3069 ENOG41060NJ transcriptional regulator BZ21_3072 ENOG4105DZC cytosine deaminase BZ21_3073 ENOG4107QZF nitrite reductase NADPH large subunit BZ21_3074 ENOG4105WZK nitrite reductase NADPH small subunit BZ21_3075 ENOG4107V9H nitrite transporter BZ21_3077 ENOG4105C31 Tryptophanyl-tRNA synthetase BZ21_3079 ENOG4105DJV ribulose-phosphate 3-epimerase BZ21_3084 ENOG4105E4G Type IV pilus BZ21_3089 ENOG4108JQC penicillin-binding protein 1A BZ21_3090 ENOG4107RK2 ADP-ribose diphosphatase NudE BZ21_3092 ENOG4105DQY intracellular growth attenuator BZ21_3093 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 BZ21_3094 ENOG4105VEJ Heat shock protein BZ21_3097 ENOG4105E0F Histidine kinase BZ21_3098 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ21_3099 ENOG4108RRZ Transcription elongation factor GreB BZ21_3100 ENOG4105BZM domain protein BZ21_3101 ENOG4105XFK Ferrous iron transport protein A BZ21_3102 ENOG4105CE1 Ferrous iron transport protein b BZ21_3104 ENOG4105RID UPF0379 protein yhcN BZ21_3106 ENOG4105MJ2 Competence protein BZ21_3108 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) BZ21_3109 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ21_311 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ21_3113 ENOG4105E98 transcriptional regulator DeoR family BZ21_3116 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BZ21_3117 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ21_3122 ENOG4108HRK Histidine kinase BZ21_3127 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ21_3129 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BZ21_3132 ENOG4105GMB type VI secretion system effector, hcp1 family BZ21_3133 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ21_3134 ENOG4105C6Z Gluconate BZ21_3135 ENOG4105DIQ Transcriptional regulator BZ21_3136 ENOG4105C2I pirin domain protein BZ21_3138 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ21_3140 ENOG4105D2N Aldolase BZ21_3142 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ21_3143 ENOG4105CNN ABC, transporter BZ21_316 ENOG4105HVQ Regulatory factor of maltose metabolism BZ21_3161 ENOG4105CBX hi0933 family BZ21_3162 ENOG4105CJ3 phosphate transporter BZ21_3164 ENOG4108M6U Universal stress protein A BZ21_3168 ENOG4105DGW oligopeptidase A BZ21_3169 ENOG4105D6S protein involved in catabolism of external DNA BZ21_317 ENOG4108JQB penicillin-binding protein 1C BZ21_3170 ENOG4105DC8 reductase BZ21_3171 ENOG4107VHA regulatoR BZ21_3172 ENOG4107QQ0 gntp family BZ21_3173 ENOG4105BZW Glycerate kinase BZ21_3178 ENOG4107H3J ribonuclease BZ21_3179 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) BZ21_318 ENOG4105DN3 alpha-2-macroglobulin domain protein BZ21_3180 ENOG41066T0 asmA family BZ21_3181 ENOG4105CMB EAL domain-containing protein BZ21_3182 ENOG4105VSH 4-oxalocrotonate tautomerase BZ21_3183 ENOG4107SS6 2-dehydro-3-deoxygluconokinase BZ21_3184 ENOG4105CS0 peptidase BZ21_3189 ENOG4108PU9 oligogalacturonate-specific porin BZ21_3190 ENOG4105BZU Histidine kinase BZ21_3191 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BZ21_3192 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BZ21_3193 ENOG4108JQ7 (ABC) transporter BZ21_3194 ENOG4105C3U ABC transporter BZ21_3195 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ21_3196 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ21_3197 ENOG4105DEF Extracellular solute-binding protein, family 5 BZ21_3199 ENOG4105D5K Hemolysin activator protein BZ21_3203 ENOG4105CXY transporter BZ21_3204 ENOG4105BZU Histidine kinase BZ21_3205 ENOG4108KX4 response regulator BZ21_3206 ENOG4105DIJ Phosphoethanolamine transferase BZ21_3208 ENOG4105C85 amino acid BZ21_321 ENOG4105C26 Dehydrogenase BZ21_3211 ENOG4105C6T cysteine synthase BZ21_3217 ENOG4105CM4 permease protein BZ21_3219 ENOG4108IPW abc transporter atp-binding protein BZ21_322 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BZ21_3222 ENOG4105DFP Integrase BZ21_3224 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures BZ21_3226 ENOG4108XS9 dna repair protein BZ21_3234 ENOG4106H3A restriction BZ21_3236 ENOG4105DZR Type I site-specific deoxyribonuclease BZ21_3238 ENOG4107XZC Restriction modification system DNA (Specificity BZ21_324 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ21_3242 ENOG4105DFP Integrase BZ21_3244 ENOG4105T16 Transcriptional regulator (AraC family) BZ21_3245 ENOG4107RNG ABC transporter BZ21_3247 ENOG4105DFW ABC transporter BZ21_3249 ENOG4105CMG Carbohydrate kinase BZ21_325 ENOG4105C2J ABC transporter BZ21_3251 ENOG4108TTM chaperone BZ21_3253 ENOG4106EAR Fimbrial protein BZ21_3254 ENOG4105MEV Acyl-transferase BZ21_3256 ENOG4105DQ6 Transposase BZ21_3258 ENOG4105C7B Threonine dehydratase BZ21_3259 ENOG4105D99 atp gtp-binding protein BZ21_326 ENOG4105CNN ABC, transporter BZ21_3260 ENOG4105R2A (LipO)protein BZ21_3264 ENOG4105JKW Valine--pyruvate aminotransferase BZ21_3266 ENOG4107T9C Alpha amylase catalytic region BZ21_3269 ENOG4108ZG0 Ompa motb domain protein BZ21_327 ENOG4105CK5 oxidoreductase BZ21_3271 ENOG4108R3E Dna-3-methyladenine glycosylase i BZ21_3274 ENOG4106JH6 (LipO)protein BZ21_3275 ENOG4105CTS PTS system mannitol-specific BZ21_3277 ENOG4105E61 Mannitol repressor protein BZ21_3279 ENOG4108YYI Protein of unknown function (DUF2810) BZ21_328 ENOG4105EDK PfkB domain protein BZ21_3282 ENOG4105C8Q Methyl-accepting chemotaxis BZ21_3283 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ21_3285 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ21_3286 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ21_3287 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BZ21_3288 ENOG4108MG3 formate dehydrogenase BZ21_3291 ENOG4105EM7 Selenocysteine-specific translation elongation factor BZ21_3292 ENOG4105D13 transposase BZ21_3298 ENOG4105DQ6 Transposase BZ21_330 ENOG4105DH8 myo-inositol catabolism BZ21_3301 ENOG410667J hydrolase BZ21_3302 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ21_3303 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BZ21_3304 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BZ21_3307 ENOG4105VG0 50S ribosomal protein l34 BZ21_3310 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BZ21_3315 ENOG4105C7N Xanthine uracil vitamin C permease BZ21_3316 ENOG4105DRP amino acid AbC transporter BZ21_3317 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 BZ21_3318 ENOG4105EAD ABC transporter BZ21_3319 ENOG4106PMH Extracellular solute-binding protein family 3 BZ21_332 ENOG4108JJ7 ABC transporter BZ21_3323 ENOG4105E2Z phosphate ABC transporter (Permease BZ21_3324 ENOG4105C8U phosphate abc transporter BZ21_3325 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BZ21_3327 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BZ21_3335 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BZ21_3337 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation BZ21_3340 ENOG4105QTB Flavodoxin BZ21_3341 ENOG4108VVK transcriptional Regulator, AsnC BZ21_3347 ENOG4108RVA ribokinase BZ21_3348 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ21_3350 ENOG4107EJG GntR family transcriptional regulator BZ21_3356 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b BZ21_3358 ENOG4105PC1 Conserved Protein BZ21_3359 ENOG4105E27 serine threonine protein kinase BZ21_336 ENOG4108N8T regulatoR BZ21_3360 ENOG4108Z33 Thiol disulfide Interchange Protein BZ21_3361 ENOG4105C2M dna polymerase I BZ21_3364 ENOG4105D4P Coproporphyrinogen iii oxidase BZ21_3365 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ21_3366 ENOG4105CUX Signal transduction histidine kinase BZ21_3367 ENOG4105C5F glutamine synthetase BZ21_3369 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 BZ21_3372 ENOG4105SUU thioesterase domain BZ21_3373 ENOG4105JV1 AsmA family BZ21_3374 ENOG4105C2W permease BZ21_3375 ENOG4105D6U Sodium Glutamate Symporter BZ21_3376 ENOG4105CB5 ATP-dependent DNA helicase recG BZ21_3377 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase BZ21_3378 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ21_3379 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BZ21_338 ENOG4105VEQ Cold shock protein BZ21_3382 ENOG4105EN6 Membrane BZ21_3383 ENOG4105DSJ YicC domain protein BZ21_3388 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BZ21_3391 ENOG4105W0E 50S ribosomal protein L33 BZ21_3395 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BZ21_3396 ENOG4105D16 lipopolysaccharide heptosyltransferase i BZ21_3397 ENOG4105XA0 heptosyltransferase ii BZ21_3399 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BZ21_34 ENOG4107VXZ Hydrolase BZ21_340 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) BZ21_3401 ENOG4105PXI polysaccharide deacetylase BZ21_3402 ENOG41063SB peptidase BZ21_3404 ENOG4107YZP Rhodanese domain protein BZ21_3405 ENOG4105VW4 glutaredoxin 3 BZ21_3408 ENOG4105D7W serine acetyltransferase BZ21_3409 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BZ21_3410 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ21_3411 ENOG4105E0F Histidine kinase BZ21_3412 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ21_3413 ENOG4105FMW periplasmic BZ21_3418 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BZ21_3420 ENOG4107QPK )-transporter BZ21_3421 ENOG4105JSC dimethylmenaquinone methyltransferase BZ21_3423 ENOG4107F9Y LysR family transcriptional regulator BZ21_3425 ENOG4105EBK exported protein BZ21_3426 ENOG4108VTS Membrane BZ21_3427 ENOG4105DP0 ferredoxin-NADP reductase BZ21_3428 ENOG4105CBT Fructose-1,6-bisphosphatase BZ21_3429 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BZ21_3430 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BZ21_3432 ENOG4108JJA ABC, transporter BZ21_3433 ENOG4108MBX Secretion Protein BZ21_3437 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BZ21_344 ENOG4105DZ1 carboxypeptidase BZ21_3440 ENOG41063M6 Cell Division Protein BZ21_3441 ENOG4105ETE Transcriptional regulator (LacI family BZ21_3443 ENOG4105C25 Primosomal protein n' BZ21_3445 ENOG4108Z12 YiaAB two helix domain-containing protein BZ21_3446 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) BZ21_3447 ENOG4105C28 cystathionine BZ21_3448 ENOG4105CFH Aspartokinase BZ21_3449 ENOG4105SYT Methylenetetrahydrofolate reductase BZ21_345 ENOG4105K6T rare lipoprotein A BZ21_3455 ENOG4105X58 receptor BZ21_3458 ENOG4107QZV Type I secretion membrane fusion protein BZ21_3459 ENOG4105YHG TonB family BZ21_346 ENOG4105CNI cell division protein FtsW BZ21_3460 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ21_3461 ENOG4105EHV domain protein BZ21_3463 ENOG4105C5Q Transcriptional regulator BZ21_3466 ENOG4108Y73 Membrane BZ21_347 ENOG4105CJN penicillin-binding protein BZ21_3476 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator BZ21_3477 ENOG4105C2J ABC transporter BZ21_3478 ENOG4107R9N ABC transporter BZ21_3480 ENOG41062B0 ABC transporter, permease BZ21_3481 ENOG4108WFC UPF0438 protein yifE BZ21_3482 ENOG4105C0P Mg chelatase subunit ChlI BZ21_3484 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit BZ21_3485 ENOG4105CM2 brancheD-chain amino acid aminotransferase BZ21_3487 ENOG4105C7B Threonine dehydratase BZ21_349 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BZ21_3493 ENOG4105EMY transcriptional regulator BZ21_3499 ENOG4108MA7 Inherit from COG: YD repeat protein BZ21_35 ENOG4105W39 Membrane BZ21_3507 ENOG4108VEV chaperone BZ21_3509 ENOG4105CW0 outer membrane usher protein BZ21_351 ENOG4105DJF DNA polymerase III, delta' subunit BZ21_3510 ENOG4105GQR Chaperone BZ21_3513 ENOG4105KQ5 peptidylprolyl cis-trans isomerase BZ21_3514 ENOG4105C4R Atp-dependent dna helicase BZ21_3517 ENOG4105K63 Thioredoxin BZ21_3519 ENOG4105ESV Glycosyl transferase, family 4 BZ21_3520 ENOG4105SFE lipopolysaccharide biosynthesis protein BZ21_3521 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BZ21_3522 ENOG4108IJ1 Dehydrogenase BZ21_3523 ENOG4105C1B dTDP-glucose 4-6-dehydratase BZ21_3524 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BZ21_3525 ENOG4108WJ1 acetyltransferase BZ21_3526 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ21_3527 ENOG4105EGZ biosynthesis protein BZ21_3531 ENOG4105C85 amino acid BZ21_3537 ENOG410601J HemY protein BZ21_3538 ENOG4105ECF c-methyltransferase BZ21_3539 ENOG41076E6 Uroporphyrinogen-III Synthase BZ21_354 ENOG4107PAI alpha helical protein BZ21_3541 ENOG4107T0K Adenylate cyclase BZ21_3546 ENOG4105S7Z (LipO)protein BZ21_3548 ENOG4105CT0 Protein of unknown function, DUF484 BZ21_3549 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ21_355 ENOG4105CDA abc transporter atp-binding protein BZ21_3550 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant BZ21_3551 ENOG4105C4R Atp-dependent dna helicase BZ21_3553 ENOG4105EQN UPF0261 protein BZ21_3555 ENOG4107QUT magnesium and cobalt transport protein CorA BZ21_3556 ENOG4105FR1 rard protein BZ21_3557 ENOG4108VUY thioesterase Superfamily protein BZ21_3558 ENOG4105HDD phospholipase BZ21_3559 ENOG4105C9U ATP-dependent DNA helicase RecQ BZ21_356 ENOG4105DRP amino acid AbC transporter BZ21_3560 ENOG4105CCF Lysine exporter protein (Lyse ygga) BZ21_3562 ENOG4108EUD Lysophospholipase BZ21_3563 ENOG4105DQF Hydrolase BZ21_3565 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BZ21_3566 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A BZ21_3568 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BZ21_3569 ENOG4108W1V Lipoprotein BZ21_357 ENOG4105EAD ABC transporter BZ21_3570 ENOG4105EX9 Membrane BZ21_3573 ENOG4107FS9 Membrane BZ21_3576 ENOG4105MG3 Membrane BZ21_3577 ENOG4106H78 methyltransferase BZ21_3578 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ21_3578 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ21_3579 ENOG4105CAK Cell division ATP-binding protein ftsE BZ21_358 ENOG4107RP9 extracellular solute-binding protein, family 3 BZ21_3580 ENOG4105CRP Part of the ABC transporter FtsEX involved in BZ21_3582 ENOG4105U59 -acetyltransferase BZ21_3583 ENOG4105CP9 extracellular ligand-binding receptor BZ21_3584 ENOG4105C32 Amino acid ABC transporter (Permease) BZ21_3585 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BZ21_3586 ENOG4105C0Z ABC transporter BZ21_3587 ENOG4108IV0 ABC, transporter BZ21_359 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BZ21_3599 ENOG4107T6V glycerophosphoryl diester phosphodiesterase BZ21_360 ENOG4108JU5 Magnesium and cobalt efflux protein BZ21_3600 ENOG4105RK9 auxin efflux carrier BZ21_3603 ENOG4105DZ2 Transcriptional regulator BZ21_3604 ENOG4105EMK carboxylate amino acid amine transporter BZ21_3606 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) BZ21_3607 ENOG4108I5U Uridine phosphorylase BZ21_3610 ENOG4108KF1 Membrane BZ21_3611 ENOG4105CGY Dna recombination protein BZ21_3613 ENOG4105JC1 sterol-binding domain protein BZ21_3615 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BZ21_3617 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BZ21_3619 ENOG4105D52 delta-aminolevulinic acid dehydratase BZ21_362 ENOG4105C9A Phoh family BZ21_3620 ENOG4105MDZ Transcriptional activator rfaH BZ21_3622 ENOG4107QK7 reductase BZ21_3626 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BZ21_3627 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BZ21_3628 ENOG4108RR8 protoporphyrinogen oxidase BZ21_3635 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BZ21_364 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ21_3643 ENOG4105PM1 preprotein translocase subunit SecE BZ21_3644 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BZ21_3652 ENOG4105D41 biosynthesis protein thiH BZ21_3655 ENOG4105D06 uba thif-type nad fad binding protein BZ21_3657 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BZ21_3662 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BZ21_3663 ENOG4105R2J Conserved Protein BZ21_3665 ENOG4108T8B Protein of unknown function (DUF1481) BZ21_3666 ENOG4105C12 Phosphoribosylglycinamide synthetase BZ21_3674 ENOG4105CMM transposase BZ21_3679 ENOG41062QD Membrane BZ21_3681 ENOG4105CK2 sodium dicarboxylate symporter BZ21_3682 ENOG4105WH1 Two component transcriptional regulator luxr family BZ21_3683 ENOG4105BZU Histidine kinase BZ21_3695 ENOG4108JIR Flagellum-specific ATP synthase BZ21_3698 ENOG41063Q7 Type III secretion system protein BZ21_3699 ENOG4108HHI Type III secretion system protein BZ21_3700 ENOG41083GP type iii secretion BZ21_3701 ENOG4108TN6 type iii secretion BZ21_3702 ENOG4108IUF type iii secretion BZ21_3703 ENOG41066VF YeeE YedE family protein BZ21_3704 ENOG4105KSU Redox protein BZ21_3705 ENOG4105EQ2 LysR family Transcriptional regulator BZ21_3706 ENOG4105C44 Serine transporter BZ21_3707 ENOG4105C28 cystathionine BZ21_3709 ENOG4105EHG Permease protein BZ21_371 ENOG4105CAQ asparagine synthetase BZ21_3710 ENOG4107R4I Periplasmic binding protein BZ21_3711 ENOG4106QJH hemin transport protein BZ21_3712 ENOG4107ENK receptor BZ21_3713 ENOG4107F3C Hemin uptake protein BZ21_3715 ENOG41090JE Utilization Protein BZ21_3716 ENOG4105D4P Coproporphyrinogen iii oxidase BZ21_372 ENOG4105D4U had-superfamily hydrolase, subfamily iia BZ21_3720 ENOG4105DAX Pfam:DUF2983 BZ21_373 ENOG4105E2R ROK family BZ21_3732 ENOG4108S1B Periplasmic chaperone protein BZ21_3739 ENOG41080IJ Diacylglycerol kinase BZ21_374 ENOG4105CE4 GlcNAc 6-P deacetylase BZ21_3741 ENOG4105MYN Zinc uptake regulation protein BZ21_3742 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ21_3743 ENOG4105P4Z Phage shock protein G BZ21_3744 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BZ21_3745 ENOG4105CDU Replicative dna helicase BZ21_3746 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ21_3747 ENOG4105CGF Aromatic amino acid aminotransferase BZ21_3748 ENOG4105MSB protein, conserved in bacteria BZ21_3749 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BZ21_3750 ENOG4108UUM single-stranded DNA-binding protein BZ21_3752 ENOG4105C0A alcohol dehydrogenase BZ21_376 ENOG4105CI1 PTS System BZ21_3765 ENOG4108SIC Transcriptional regulator BZ21_3766 ENOG4105BZ8 glutamate synthase BZ21_3767 ENOG4108RC0 Electron transport protein BZ21_3768 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ21_3771 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ21_3776 ENOG4108ZVF (LipO)protein BZ21_3777 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BZ21_3779 ENOG4105KPY Small multidrug resistance protein BZ21_3780 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) BZ21_3785 ENOG4105EGS Mechanosensitive ion channel BZ21_3794 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BZ21_3795 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BZ21_3796 ENOG4105K8N protein family UPF0079, ATPase BZ21_3797 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ21_38 ENOG4108JU6 CBS domain protein BZ21_380 ENOG41090R7 Ferric uptake BZ21_3801 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BZ21_3802 ENOG4107QJR hflk protein BZ21_3803 ENOG4105EPW hflc protein BZ21_3807 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BZ21_3808 ENOG4105C2N RNA methyltransferase TrmH family group 3 BZ21_3809 ENOG4105CSU acyl-Coa dehydrogenase BZ21_381 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) BZ21_3810 ENOG4105WSB biofilm stress and motility protein A BZ21_3811 ENOG4108MXZ Esterase BZ21_3813 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BZ21_3814 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BZ21_3817 ENOG4105FHY Opacity-associated protein A BZ21_3818 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ21_382 ENOG4105NNH LexA regulated protein BZ21_3820 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BZ21_3821 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BZ21_3822 ENOG4108UUE Transcriptional regulator BZ21_3823 ENOG41061GZ Protein of unknown function (DUF1107) BZ21_3824 ENOG4105C37 (CBS) domain BZ21_3826 ENOG4105CFU surface antigen BZ21_3827 ENOG4105MA0 exported protein BZ21_3828 ENOG4108ZHD aig2 family BZ21_3829 ENOG4105F0N pyrophosphate phospho-hydrolase BZ21_3831 ENOG4105DFU Cell wall formation (By similarity) BZ21_3835 ENOG4105HVQ Regulatory factor of maltose metabolism BZ21_3837 ENOG4105EAH synthase BZ21_384 ENOG4105EV9 Alpha Beta Hydrolase BZ21_3840 ENOG4105QYV Membrane BZ21_3844 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase BZ21_3845 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BZ21_3846 ENOG4105HBR Rna-binding protein BZ21_3848 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BZ21_3849 ENOG4105EEI dihydropteroate synthase BZ21_3855 ENOG4105CHV Transcription elongation factor NusA BZ21_3862 ENOG4105C1J atp-dependent rna helicase BZ21_3865 ENOG4105DEN Luciferase family BZ21_3868 ENOG4105BZS acriflavin resistance protein BZ21_3869 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BZ21_387 ENOG4105DFP Integrase BZ21_3870 ENOG4106RZ4 Peptidase U32 BZ21_3871 ENOG4105CFP Peptidase U32 BZ21_3872 ENOG4105XPQ lipid carrier protein BZ21_3873 ENOG4108YYD acetyltransferase BZ21_3878 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BZ21_3879 ENOG4105DRS transport system, permease BZ21_3883 ENOG4105K4T epimerase BZ21_3884 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein BZ21_3885 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) BZ21_3886 ENOG4105FD8 phosphonate metabolism protein PhnM BZ21_3887 ENOG4105HRV phosphonate c-p lyase system protein phnl BZ21_3888 ENOG4105ENV phosphonate C-P lyase system protein PhnK BZ21_3889 ENOG4105FT8 Phosphonate metabolism BZ21_389 ENOG4108Z1B Cyclase dehydrase BZ21_3890 ENOG4105EKV Phosphonate metabolism protein BZ21_3891 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH BZ21_3892 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG BZ21_3893 ENOG4107RJJ Transcriptional regulator BZ21_3895 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BZ21_3896 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BZ21_3897 ENOG4108JQ7 (ABC) transporter BZ21_3898 ENOG4105C3U ABC transporter BZ21_3899 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ21_39 ENOG4106KVJ cytochrome C assembly protein BZ21_3900 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ21_3902 ENOG4105XEP YhcH YjgK YiaL family protein BZ21_3904 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) BZ21_3905 ENOG4108MJ3 acetyltransferase BZ21_3907 ENOG4105MYG DNA polymerase iii, chi subunit BZ21_3909 ENOG4108M8S permease YjgP YjgQ family protein BZ21_391 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ21_3910 ENOG4108K5H permease YjgP YjgQ family protein BZ21_3915 ENOG4105DZR Type I site-specific deoxyribonuclease BZ21_3919 ENOG4108M3P Membrane BZ21_392 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BZ21_3921 ENOG4108XCZ PTS System BZ21_3922 ENOG4106R3P AraC family transcriptional regulator BZ21_3923 ENOG4108YRF PTS System BZ21_3924 ENOG4105DM4 PTS System BZ21_3925 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BZ21_3926 ENOG4105RI1 glycoprotein receptor BZ21_3933 ENOG4105DKT Transcriptional regulator BZ21_3935 ENOG4105DKP glycosyl transferase, family 9 BZ21_3937 ENOG4105C9B Cysteine desulfurase BZ21_3943 ENOG410624X efflux transporter, rnd family, mfp subunit BZ21_3944 ENOG4105BZS acriflavin resistance protein BZ21_3947 ENOG4105BZU Histidine kinase BZ21_3948 ENOG4105YBH Protein of unknown function (DUF1435) BZ21_395 ENOG4105BZN citrate synthase BZ21_3953 ENOG4108WPU DNA polymerase III subunit psi BZ21_3954 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BZ21_3956 ENOG4105K3G Periplasmic Protein BZ21_3958 ENOG4108NRW Phospholipase, patatin family BZ21_3959 ENOG4105EYA deoxyribonuclease BZ21_396 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BZ21_3960 ENOG4105D9N nucleoside BZ21_3961 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ21_3965 ENOG41062Z9 Membrane BZ21_3966 ENOG4105EAC phosphoserine phosphatase BZ21_3967 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BZ21_3968 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase BZ21_397 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BZ21_3970 ENOG4105C5H ABC transporter BZ21_3971 ENOG41090EK ompa motb domain protein BZ21_3972 ENOG4108KHX Diguanylate cyclase BZ21_3975 ENOG4107SC1 transglycosylase BZ21_3977 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) BZ21_3978 ENOG4105UEI Transcriptional Regulator AraC Family BZ21_3981 ENOG4108RH0 Crea protein BZ21_3982 ENOG41065U4 response regulator BZ21_399 ENOG4105E33 succinate dehydrogenase BZ21_3990 ENOG4108RIR Molybdenum cofactor biosynthesis protein BZ21_3993 ENOG4106HK8 GPR1 FUN34 yaaH family protein BZ21_3997 ENOG41063Z6 transcriptional regulator, lysR family BZ21_3999 ENOG4105DTN riboflavin biosynthesis protein ribF BZ21_4 ENOG4105C2J ABC transporter BZ21_40 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BZ21_400 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BZ21_4002 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BZ21_4006 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BZ21_4007 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BZ21_4008 ENOG4108NIW Leucine export protein LeuE BZ21_4009 ENOG4105DWK Membrane BZ21_401 ENOG4105C7S Dehydrogenase BZ21_4011 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BZ21_4017 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BZ21_4020 ENOG4105D3G Pseudouridine synthase BZ21_4029 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ21_403 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BZ21_4030 ENOG4105CS6 Rhs element vgr protein BZ21_404 ENOG4105C4M (Ubiquinol oxidase) subunit I BZ21_4041 ENOG4105CQ2 DNA polymerase BZ21_4042 ENOG4108KF1 Membrane BZ21_4044 ENOG4106SMU thiamine transporter membrane protein BZ21_4045 ENOG4105DP9 ABC transporter BZ21_4048 ENOG4105CMM transposase BZ21_405 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BZ21_4050 ENOG4105S8Q sugar efflux transporter BZ21_4057 ENOG41064T2 transcriptional regulator, lysR family BZ21_4058 ENOG4108IQE Amp-dependent synthetase and ligase BZ21_4059 ENOG4105C7K acetolactate synthase BZ21_4060 ENOG4108ZP8 Acetolactate synthase small subunit BZ21_4061 ENOG4107B7Y DNA-binding transcriptional regulator FruR BZ21_4062 ENOG4108RNS Exports L-alanine (By similarity) BZ21_4065 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BZ21_4066 ENOG4105CJN penicillin-binding protein BZ21_4067 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BZ21_4068 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BZ21_407 ENOG4105KJB cyd operon protein YbgE BZ21_4071 ENOG4105CNI cell division protein FtsW BZ21_4075 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BZ21_4076 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BZ21_4077 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BZ21_408 ENOG4107YD3 Thioesterase BZ21_4082 ENOG4105M6F mutator MutT protein BZ21_4083 ENOG4108RS6 transposase BZ21_4086 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BZ21_4089 ENOG4105D7Q type ii secretion system BZ21_409 ENOG4105E02 MotA TolQ exbB proton channel BZ21_4090 ENOG4107QHF type ii secretion system protein e BZ21_4091 ENOG4108ZUW Major pilin subunit BZ21_4092 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BZ21_4093 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ21_4094 ENOG4106A72 regulatory protein AmpE BZ21_4095 ENOG4105C85 amino acid BZ21_4096 ENOG41073TP transcriptional regulator BZ21_4097 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BZ21_4098 ENOG4107QSN dihydrolipoamide acetyltransferase BZ21_4099 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ21_410 ENOG4105M8F Biopolymer transport protein exbD tolR BZ21_4100 ENOG4107QIJ Aconitate hydratase 2 BZ21_4102 ENOG4105RPH Inner membrane protein YddG BZ21_4105 ENOG4108ZRK uncharacterized protein yacC BZ21_4106 ENOG4105E3B Multicopper oxidase BZ21_4107 ENOG4108UGV hypoxanthine phosphoribosyltransferase BZ21_4108 ENOG41077A9 carbonic anhydrase BZ21_4109 ENOG4105DA5 (ABC) transporter BZ21_411 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ21_411 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ21_4110 ENOG4105E3A (ABC) transporter BZ21_4111 ENOG4107BJW polysaccharide deacetylase BZ21_4115 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BZ21_4116 ENOG4105DJ0 Poly(A) Polymerase BZ21_4118 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BZ21_4120 ENOG4107XID 2'-5' rna ligase BZ21_4121 ENOG4105CQ7 ATP-dependent helicase BZ21_4122 ENOG4105BZ4 penicillin-binding protein BZ21_4123 ENOG4105E0A ABC, transporter BZ21_4124 ENOG4105J76 Periplasmic binding protein BZ21_4125 ENOG4105S6R Iron-hydroxamate transporter permease subunit BZ21_4129 ENOG4105EN6 Membrane BZ21_413 ENOG4105KCK Peptidoglycan-associated lipoprotein BZ21_4133 ENOG4105C0H protease BZ21_4134 ENOG4105BZU Histidine kinase BZ21_4135 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ21_4136 ENOG4105DXN mazG family BZ21_414 ENOG4105UFD tol-pal system protein YbgF BZ21_4140 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BZ21_4141 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BZ21_4150 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BZ21_4151 ENOG4105N0Z inner membrane protein ygbE BZ21_4158 ENOG4108K5P (LipO)protein BZ21_4159 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ21_4161 ENOG4108YZG isomerase BZ21_4162 ENOG4105CPQ Dehydrogenase BZ21_4163 ENOG4105CHR reductase BZ21_4164 ENOG4105CMT Dihydroxyacetone kinase BZ21_4166 ENOG4105DKT Transcriptional regulator BZ21_4171 ENOG4105E89 ABC transporter BZ21_4172 ENOG4105CA0 peroxidase BZ21_4175 ENOG4105D05 Receptor BZ21_4177 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ21_4179 ENOG4107GFK fumarate BZ21_4180 ENOG4105CMG Carbohydrate kinase BZ21_423 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BZ21_424 ENOG4105PGM cation diffusion facilitator family transporter BZ21_426 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ21_429 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BZ21_431 ENOG4105F0Z galactose-1-phosphate uridylyltransferase BZ21_432 ENOG4105CMR udp-glucose 4-epimerase BZ21_435 ENOG4105DKW ABC transporter BZ21_436 ENOG4105F4R Transcriptional regulator mode BZ21_437 ENOG410680R Protein of unknown function (DUF2592) BZ21_438 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BZ21_439 ENOG4105E0C molybdate abc transporter BZ21_441 ENOG4108K4B hydrolase BZ21_446 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BZ21_447 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ21_448 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BZ21_45 ENOG4108NE3 Salt-induced outer membrane protein BZ21_450 ENOG4105VYA Uncharacterized conserved protein (DUF2132) BZ21_451 ENOG4105CHW UPF0052 protein BZ21_453 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BZ21_455 ENOG4105M00 molybdopterin converting factor, subunit 1 BZ21_456 ENOG4108ZAF Molybdopterin BZ21_457 ENOG4105HFZ Membrane BZ21_46 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ21_461 ENOG4105C94 Transporter BZ21_462 ENOG4105CN8 Transcriptional regulator BZ21_464 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BZ21_465 ENOG4105EAA nucleoside BZ21_467 ENOG4105BZU Histidine kinase BZ21_47 ENOG4108NEV two component transcriptional regulator, LytTR family BZ21_470 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ21_472 ENOG4107QWP ABC-2 type transporter BZ21_473 ENOG4107QWP ABC-2 type transporter BZ21_474 ENOG4105CJ1 ABC, transporter BZ21_476 ENOG4107MVR Transcriptional regulator BZ21_477 ENOG4105C1J atp-dependent rna helicase BZ21_478 ENOG4105EQR Transposase IS116 IS110 IS902 BZ21_48 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ21_483 ENOG4105EQR Transposase IS116 IS110 IS902 BZ21_484 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BZ21_486 ENOG41061WM D-Alanyl-D-Alanine BZ21_487 ENOG4105CXG d-lactate dehydrogenase BZ21_489 ENOG4105N1F Hnh endonuclease BZ21_49 ENOG4105EHE chorismate mutase- prephenate dehydrogenase BZ21_491 ENOG4105Y3U Transglycosylase-associated protein BZ21_493 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein BZ21_496 ENOG4108W15 Protein of unknown function (DUF1456) BZ21_498 ENOG4105C32 Amino acid ABC transporter (Permease) BZ21_499 ENOG4105CNN ABC, transporter BZ21_500 ENOG4108JJB ABC transporter BZ21_501 ENOG4108IV0 ABC, transporter BZ21_504 ENOG4105KHC sulfurtransferase BZ21_505 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BZ21_506 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component BZ21_507 ENOG4108IJ8 ABC transporter BZ21_508 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component BZ21_509 ENOG4105D5Q Arginine ornithine antiporter BZ21_51 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ21_510 ENOG4105CXN decarboxylase BZ21_512 ENOG4105FDR Membrane BZ21_514 ENOG4105DVT helicase BZ21_515 ENOG4105CH6 catalase BZ21_516 ENOG4108UII YfaZ family BZ21_517 ENOG4105E0U tyrosine-specific transport protein BZ21_52 ENOG4108IMY Transcriptional regulator BZ21_520 ENOG4105XPH Ferredoxin BZ21_521 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ21_522 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ21_524 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ21_525 ENOG4105BZU Histidine kinase BZ21_526 ENOG41068CG regulatoR BZ21_527 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC BZ21_528 ENOG4106UW1 Major Facilitator superfamily BZ21_530 ENOG4105FCK Membrane BZ21_533 ENOG4107R6D beta-lactam binding protein AmpH BZ21_534 ENOG4105CT4 transporter BZ21_536 ENOG4105C8Q Methyl-accepting chemotaxis BZ21_539 ENOG4105Y50 Virulence Protein BZ21_541 ENOG4105HRS Antitermination protein BZ21_542 ENOG4105G63 Type III effector Hrp-dependent BZ21_544 ENOG4105MVE transcriptional regulator BZ21_545 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BZ21_549 ENOG4105TKZ Tail Sheath BZ21_557 ENOG4108T86 baseplate J family protein BZ21_560 ENOG4108Q3X Transcriptional regulator BZ21_562 ENOG4105CS2 ec 3.2.1.21 BZ21_567 ENOG4105GMB type VI secretion system effector, hcp1 family BZ21_570 ENOG4105E68 Sulfatase BZ21_571 ENOG4105PAN UPF0352 protein BZ21_574 ENOG4105CFI type iii restriction protein res subunit BZ21_575 ENOG4105I08 Pseudouridine synthase BZ21_576 ENOG4105C2C drug resistance transporter, Bcr CflA BZ21_577 ENOG4105HG6 BZ21_578 ENOG4108JQ5 ABC transporter BZ21_579 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BZ21_58 ENOG4108IRC dna polymerase iii BZ21_580 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BZ21_581 ENOG4105E43 Extracellular solute-binding protein, family 5 BZ21_582 ENOG4105CXC rtn protein BZ21_583 ENOG4107TT5 NLP P60 protein BZ21_584 ENOG41076MN Phosphoesterase, PA-phosphatase related BZ21_585 ENOG4105CKI cobalamin synthesis protein BZ21_587 ENOG4107YCY Transcriptional regulator BZ21_588 ENOG4105DEI Mannitol dehydrogenase BZ21_59 ENOG4105DFE Dna adenine methylase BZ21_592 ENOG4105KRS Proteinase inhibitor BZ21_593 ENOG4105CHR reductase BZ21_596 ENOG4105C26 Dehydrogenase BZ21_6 ENOG4105E98 transcriptional regulator DeoR family BZ21_60 ENOG4105VZ1 Replication Protein BZ21_601 ENOG4105C2J ABC transporter BZ21_602 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BZ21_604 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein BZ21_605 ENOG4105DE4 1-phosphofructokinase BZ21_606 ENOG4105DM4 PTS System BZ21_607 ENOG4108SGD regulatory protein BZ21_610 ENOG4108UIF Chaperone BZ21_611 ENOG4108D1K outer membrane usher protein BZ21_613 ENOG4105HMI Membrane BZ21_614 ENOG4105DUM transcriptional regulator, lysR family BZ21_616 ENOG4108IQI permease BZ21_618 ENOG4105EHG Permease protein BZ21_62 ENOG4105ED4 portal protein BZ21_620 ENOG4105D05 Receptor BZ21_621 ENOG4108TGY Glutathione S-transferase BZ21_624 ENOG4105D01 (LipO)protein BZ21_626 ENOG4108UMI ABC transporter, permease BZ21_627 ENOG4105DZ1 carboxypeptidase BZ21_628 ENOG4105C44 Serine transporter BZ21_629 ENOG4107FB0 transcriptional regulator DeoR family BZ21_630 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ21_631 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BZ21_633 ENOG4105D0C transport protein BZ21_634 ENOG41090BQ Glutaredoxin BZ21_635 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress BZ21_636 ENOG4108RMJ sensory transduction regulator BZ21_637 ENOG4107RUE extracellular solute-binding protein family 1 BZ21_638 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ21_639 ENOG4105F38 ABC transporter, permease BZ21_640 ENOG4105D38 putrescine abc transporter BZ21_641 ENOG4105RBQ inner membrane protein ybjO BZ21_643 ENOG4106TNF Periplasmic binding protein BZ21_646 ENOG4108I9K permease protein BZ21_647 ENOG4105E0A ABC, transporter BZ21_648 ENOG410642S Nicotianamine synthase protein BZ21_649 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) BZ21_650 ENOG4108I0N Transporter, RarD family, DMT superfamily protein BZ21_651 ENOG4105DMR ABC, transporter BZ21_652 ENOG4105GBT ABC transporter BZ21_653 ENOG4106PMH Extracellular solute-binding protein family 3 BZ21_654 ENOG4105E5Z arginine transporter ATP-binding subunit BZ21_655 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) BZ21_656 ENOG41064MM (LipO)protein BZ21_657 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ21_658 ENOG4105CGD Nad-dependent epimerase dehydratase BZ21_659 ENOG4105C5W Aldolase BZ21_660 ENOG4105C7K acetolactate synthase BZ21_661 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ21_663 ENOG4105DWU Membrane BZ21_664 ENOG4105CPB ATP-dependent endonuclease of the OLD family BZ21_665 ENOG4108MJ5 VirK protein BZ21_666 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ21_668 ENOG4105VEQ Cold shock protein BZ21_670 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ21_671 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BZ21_673 ENOG4108JJ8 (ABC) transporter BZ21_674 ENOG4108JJ9 ABC, transporter BZ21_675 ENOG4105C3M thioredoxin reductase BZ21_676 ENOG4105EW9 transcriptional regulator AsnC family BZ21_677 ENOG4105CNU cell division protein FtsK BZ21_680 ENOG4105D1H recombination factor protein RarA BZ21_682 ENOG4108ISG Major Facilitator BZ21_683 ENOG4105F1A Pyruvate formate-lyase BZ21_685 ENOG4105C6N Formate acetyltransferase BZ21_686 ENOG4105TMB Formate nitrite transporter BZ21_687 ENOG4105DDY UPF0142 protein ycaO BZ21_688 ENOG4105HDK L-asparaginase BZ21_694 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BZ21_697 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BZ21_7 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ21_700 ENOG4105E32 cytoplasmic protein BZ21_701 ENOG4105VEQ Cold shock protein BZ21_702 ENOG4105W49 UPF0434 protein BZ21_704 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups BZ21_705 ENOG4106371 Methyltransferase BZ21_706 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) BZ21_707 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) BZ21_709 ENOG4105DIT ErfK YbiS YcfS YnhG family protein BZ21_710 ENOG4105EAQ (twin-arginine translocation) pathway signal BZ21_711 ENOG4105C5X domain protein BZ21_712 ENOG4105CGF Aromatic amino acid aminotransferase BZ21_716 ENOG4105CD8 aminopeptidase N BZ21_718 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) BZ21_719 ENOG4105QVC MOSC domain-containing protein BZ21_721 ENOG4105C5H ABC transporter BZ21_722 ENOG4105F1S paraquat-inducible protein a BZ21_723 ENOG4105DY2 Paraquat-inducible protein b BZ21_724 ENOG4108Q2G (LipO)protein BZ21_725 ENOG4108RS6 transposase BZ21_726 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ21_729 ENOG4105DAN ATP-dependent protease BZ21_731 ENOG4105UYK outer membrane protein a BZ21_733 ENOG4108RZ1 DNA transformation protein BZ21_734 ENOG4105EM2 membrane BZ21_735 ENOG410901E Membrane BZ21_736 ENOG41088T4 Helicase IV BZ21_738 ENOG4108Q67 UPF0319 protein BZ21_739 ENOG4105K4P CoA-binding domain protein BZ21_742 ENOG4108I1J Integrase BZ21_755 ENOG4105CDU Replicative dna helicase BZ21_762 ENOG4105RWQ Protein of unknown function (DUF1364) BZ21_767 ENOG4105SZK Rz endopeptidase from lambdoid prophage DLP12 BZ21_799 ENOG4108Z0T Part of a sulfur-relay system (By similarity) BZ21_8 ENOG4107QY8 reductase BZ21_80 ENOG4108X9F tail fiber protein BZ21_802 ENOG4108BUD transposase BZ21_808 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BZ21_809 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ21_810 ENOG4105CHR reductase BZ21_811 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BZ21_813 ENOG4108KQ6 Enoyl-CoA hydratase BZ21_814 ENOG4105CHR reductase BZ21_816 ENOG41062T2 Acyl carrier protein BZ21_817 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ21_823 ENOG4105CDV Ompa motb domain protein BZ21_825 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ21_844 ENOG4105C5H ABC transporter BZ21_846 ENOG4105D06 uba thif-type nad fad binding protein BZ21_847 ENOG4105CVM Molybdenum cofactor synthesis domain protein BZ21_85 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA BZ21_850 ENOG4105C19 ABC transporter BZ21_851 ENOG4105ENT Efflux transporter rnd family, mfp subunit BZ21_856 ENOG4105EGI Transcriptional regulator BZ21_857 ENOG4105CBP Major Facilitator BZ21_859 ENOG4105DHF Membrane BZ21_86 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BZ21_862 ENOG4108HWV )-transporter BZ21_863 ENOG4107GZ4 SanA protein BZ21_866 ENOG41067MG lrgb family BZ21_868 ENOG4105E5W Transporter BZ21_87 ENOG4105C34 Pseudouridine synthase BZ21_873 ENOG4105D1F ATP-binding protein BZ21_876 ENOG4108GAE asmA family BZ21_877 ENOG4105EE5 Membrane protein terC BZ21_878 ENOG4108819 ferric iron reductase BZ21_879 ENOG4105DY8 decarboxylase BZ21_88 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ21_880 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ21_882 ENOG4105DUU IucA IucC family protein BZ21_883 ENOG4105E0A ABC, transporter BZ21_884 ENOG4105TVJ transport system, permease BZ21_885 ENOG4105DQ5 transport system permease protein BZ21_886 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BZ21_887 ENOG4105CNM Receptor BZ21_888 ENOG4105DUU IucA IucC family protein BZ21_889 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ21_89 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ21_890 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ21_891 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BZ21_892 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BZ21_895 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BZ21_9 ENOG4105QAX Iron-sulfur BZ21_900 ENOG4108535 NAD dependent epimerase/dehydratase family BZ21_903 ENOG4105CNN ABC, transporter BZ21_904 ENOG4105C2J ABC transporter BZ21_905 ENOG4107SCQ Iron-containing alcohol dehydrogenase BZ21_907 ENOG4105CUB amino acid BZ21_908 ENOG4105CJB Exodeoxyribonuclease I BZ21_911 ENOG4105TNG K13735 adhesin invasin BZ21_912 ENOG4105CSP Major Facilitator Superfamily BZ21_913 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BZ21_914 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BZ21_916 ENOG4105DIA mandelate racemase muconate lactonizing BZ21_920 ENOG4105UQX Mate efflux family protein BZ21_924 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BZ21_934 ENOG4107ZSV Receptor BZ21_935 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BZ21_939 ENOG4105C0W non-ribosomal peptide synthetase BZ21_942 ENOG4105BZ1 (ABC) transporter BZ21_943 ENOG4105EYM Major Facilitator superfamily BZ21_948 ENOG4108KX4 response regulator BZ21_949 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BZ21_95 ENOG4105T42 (LipO)protein BZ21_951 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BZ21_952 ENOG4108TSE Transferase BZ21_956 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BZ21_96 ENOG4105JIM Phosphatidylserine synthase BZ21_962 ENOG4105BZ1 (ABC) transporter BZ21_966 ENOG4105N4N Protein of unknown function (DUF2766) BZ21_967 ENOG4105TIK BZ21_968 ENOG41064PC BZ21_97 ENOG4105CD5 CoA-binding domain protein BZ21_971 ENOG4105C85 amino acid BZ21_974 ENOG4105VEQ Cold shock protein BZ21_975 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ21_976 ENOG4105DHI Methyltransferase BZ21_978 ENOG4105BZU Histidine kinase BZ21_98 ENOG4106IUH DTW domain containing protein BZ21_982 ENOG4105F3R pts system mannose fructose sorbose family iid BZ21_983 ENOG4105ETZ PTS System BZ21_984 ENOG4108EQA pts system BZ21_985 ENOG4105EE5 Membrane protein terC BZ21_986 ENOG4108V8F Transcriptional regulator, MarR family BZ21_989 ENOG4105C26 Dehydrogenase BZ21_99 ENOG4105K63 Thioredoxin BZ21_990 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase BZ21_995 ENOG4105EFA 4-hydroxyphenylacetate BZ21_996 ENOG4107UWN reductase BZ21_997 ENOG4105EJQ L-serine dehydratase BZ21_999 ENOG4105CRQ synthase (Component I)