locus-tag	class	description
YPTS_0002	COG0592	DNA-directed DNA polymerase activity
YPTS_0004	COG0187	DNA topoisomerase II activity
YPTS_0005	COG0561	phosphatase activity
YPTS_0007	COG2801	Transposase and inactivated derivatives
YPTS_0013	COG3328	transposase activity
YPTS_0014	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPTS_0016	COG3084	Protein conserved in bacteria
YPTS_0017	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPTS_0018	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPTS_0019	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPTS_0019	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPTS_0022	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPTS_0024	COG3852	Histidine kinase
YPTS_0025	COG0174	glutamine synthetase
YPTS_0027	COG1011	Hydrolase
YPTS_0030	COG0456	acetyltransferase
YPTS_0031	COG2982	Protein involved in outer membrane biogenesis
YPTS_0032	COG2233	PERMEase
YPTS_0033	COG0786	glutamate:sodium symporter activity
YPTS_0034	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPTS_0035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPTS_0036	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPTS_0037	COG1758	RNA polymerase activity
YPTS_0040	COG2860	membrane
YPTS_0042	COG1561	YicC-like family, N-terminal region
YPTS_0047	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YPTS_0050	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YPTS_0054	COG1519	Transferase
YPTS_0055	COG0859	PFAM glycosyl transferase family 9
YPTS_0056	COG0859	PFAM glycosyl transferase family 9
YPTS_0058	COG0156	8-amino-7-oxononanoate synthase activity
YPTS_0060	COG2861	carbohydrate metabolic process
YPTS_0061	COG4942	peptidase
YPTS_0063	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPTS_0064	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPTS_0067	COG1045	serine acetyltransferase
YPTS_0068	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPTS_0069	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPTS_0069	COG2169	Transcriptional regulator
YPTS_0070	COG2205	protein histidine kinase activity
YPTS_0071	COG0745	RESPONSE REGULATOR receiver
YPTS_0072	COG3678	ATP-independent chaperone mediated protein folding
YPTS_0078	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPTS_0081	COG0471	metal ion transport
YPTS_0082	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPTS_0083	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPTS_0084	COG0583	DNA-binding transcription factor activity
YPTS_0087	COG3152	Membrane
YPTS_0089	COG1494	fructose-1,6-bisphosphatase
YPTS_0090	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPTS_0091	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YPTS_0098	COG1575	Belongs to the MenA family. Type 1 subfamily
YPTS_0101	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPTS_0102	COG1609	Transcriptional regulator
YPTS_0104	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPTS_0106	COG4682	membrane
YPTS_0107	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
YPTS_0108	COG0626	cystathionine gamma-synthase activity
YPTS_0109	COG0460	homoserine dehydrogenase
YPTS_0109	COG0527	aspartate kinase activity
YPTS_0119	COG1629	transport
YPTS_0124	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPTS_0125	COG0678	peroxiredoxin activity
YPTS_0125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPTS_0136	COG1879	ABC-type sugar transport system periplasmic component
YPTS_0137	COG1129	ABC transporter
YPTS_0138	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_0139	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_0141	COG3085	chromosome segregation
YPTS_0144	COG3978	acetolactate synthase activity
YPTS_0145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPTS_0153	COG0583	DNA-binding transcription factor activity
YPTS_0167	COG3121	Chaperone
YPTS_0170	COG3121	Chaperone
YPTS_0173	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPTS_0178	COG3118	belongs to the thioredoxin family
YPTS_0179	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPTS_0180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YPTS_0181	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPTS_0182	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPTS_0183	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPTS_0184	COG1088	dTDP-glucose 4,6-dehydratase activity
YPTS_0185	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPTS_0186	COG0456	acetyltransferase
YPTS_0187	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPTS_0188	COG2244	polysaccharide biosynthetic process
YPTS_0192	COG1113	amino acid transport
YPTS_0193	COG3071	HemY protein
YPTS_0194	COG2959	enzyme of heme biosynthesis
YPTS_0195	COG1587	Uroporphyrinogen-III synthase
YPTS_0197	COG3072	Adenylate cyclase
YPTS_0199	COG3328	transposase activity
YPTS_0202	COG5567	small periplasmic lipoprotein
YPTS_0204	COG3159	Protein conserved in bacteria
YPTS_0205	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPTS_0206	COG1011	Hydrolase
YPTS_0207	COG0210	DNA helicase
YPTS_0209	COG5441	Belongs to the UPF0261 family
YPTS_0210	COG5564	TIM-barrel signal transduction protein
YPTS_0213	COG0598	Magnesium transport protein CorA
YPTS_0215	COG2050	protein possibly involved in aromatic compounds catabolism
YPTS_0216	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YPTS_0217	COG0514	ATP-dependent DNA helicase (RecQ)
YPTS_0218	COG1280	lysine exporter protein (LysE YggA)
YPTS_0219	COG1280	lysine exporter protein (LysE YggA)
YPTS_0220	COG2267	carboxylic ester hydrolase activity
YPTS_0221	COG0561	phosphatase activity
YPTS_0223	COG0584	glycerophosphoryl diester phosphodiesterase
YPTS_0224	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPTS_0226	COG0247	lactate metabolic process
YPTS_0228	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPTS_0231	COG3714	YhhN family
YPTS_0234	COG3776	membrane
YPTS_0235	COG0742	ribosomal rna small subunit methyltransferase
YPTS_0236	COG0552	protein localization to endoplasmic reticulum
YPTS_0236	COG0552	protein localization to endoplasmic reticulum
YPTS_0237	COG2884	Cell division ATP-binding protein ftsE
YPTS_0238	COG2177	Part of the ABC transporter FtsEX involved in
YPTS_0241	COG0683	leucine binding
YPTS_0242	COG0559	Belongs to the binding-protein-dependent transport system permease family
YPTS_0243	COG4177	L-phenylalanine transmembrane transporter activity
YPTS_0244	COG0411	ABC transporter
YPTS_0245	COG0410	ABC transporter
YPTS_0258	COG0584	glycerophosphoryl diester phosphodiesterase
YPTS_0259	COG0679	Auxin Efflux Carrier
YPTS_0263	COG0583	DNA-binding transcription factor activity
YPTS_0265	COG0412	Dienelactone hydrolase
YPTS_0266	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
YPTS_0268	COG1966	Carbon starvation protein
YPTS_0269	COG0586	Pfam SNARE associated Golgi protein
YPTS_0270	COG1322	Protein conserved in bacteria
YPTS_0274	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPTS_0276	COG0805	protein transport
YPTS_0285	COG1739	Uncharacterized protein family UPF0029
YPTS_0286	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPTS_0287	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YPTS_0297	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPTS_0298	COG0250	Participates in transcription elongation, termination and antitermination
YPTS_0309	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YPTS_0311	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YPTS_0316	COG1515	deoxyribonuclease V activity
YPTS_0317	COG3068	Protein conserved in bacteria
YPTS_0320	COG0151	Belongs to the GarS family
YPTS_0326	COG2801	Transposase and inactivated derivatives
YPTS_0331	COG3162	membrane
YPTS_0333	COG1301	dicarboxylic acid transport
YPTS_0334	COG2197	response regulator
YPTS_0355	COG2391	methyltransferase activity
YPTS_0356	COG0425	Belongs to the sulfur carrier protein TusA family
YPTS_0357	COG0583	DNA-binding transcription factor activity
YPTS_0358	COG0814	amino acid
YPTS_0359	COG0626	cystathionine gamma-synthase activity
YPTS_0361	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_0362	COG4558	Periplasmic binding protein
YPTS_0363	COG3720	iron ion transport
YPTS_0364	COG4771	TonB-dependent receptor
YPTS_0366	COG0702	epimerase
YPTS_0367	COG3721	Heme iron utilization protein
YPTS_0372	COG1358	cellular component organization or biogenesis
YPTS_0384	COG3121	Chaperone
YPTS_0392	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPTS_0394	COG0735	belongs to the Fur family
YPTS_0395	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPTS_0398	COG0305	Participates in initiation and elongation during chromosome replication
YPTS_0399	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPTS_0400	COG1448	Aminotransferase
YPTS_0401	COG2315	Protein conserved in bacteria
YPTS_0402	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPTS_0403	COG0629	single-stranded DNA binding
YPTS_0405	COG1454	alcohol dehydrogenase
YPTS_0421	COG1309	transcriptional regulator
YPTS_0422	COG0493	'glutamate synthase
YPTS_0422	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPTS_0423	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPTS_0424	COG3383	formate dehydrogenase (NAD+) activity
YPTS_0427	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPTS_0435	COG2076	Multidrug Resistance protein
YPTS_0436	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPTS_0438	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPTS_0439	COG1053	succinate dehydrogenase
YPTS_0441	COG1511	domain protein
YPTS_0441	COG3264	Mechanosensitive ion channel
YPTS_0447	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPTS_0448	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YPTS_0448	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YPTS_0449	COG0802	atpase or kinase
YPTS_0450	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPTS_0455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPTS_0456	COG0330	HflC and HflK could
YPTS_0457	COG0330	HflC and HflK could
YPTS_0458	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YPTS_0461	COG0557	exoribonuclease II activity
YPTS_0462	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPTS_0464	COG1960	acyl-CoA dehydrogenase activity
YPTS_0465	COG3650	response to hydrogen peroxide
YPTS_0466	COG1073	alpha beta
YPTS_0468	COG0360	Binds together with S18 to 16S ribosomal RNA
YPTS_0470	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YPTS_0473	COG3061	Opacity-associated protein A
YPTS_0474	COG0545	Peptidyl-prolyl cis-trans isomerase
YPTS_0476	COG0737	Belongs to the 5'-nucleotidase family
YPTS_0478	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPTS_0480	COG1253	flavin adenine dinucleotide binding
YPTS_0482	COG0729	surface antigen
YPTS_0483	COG2911	Protein conserved in bacteria
YPTS_0484	COG2105	PFAM AIG2 family protein
YPTS_0485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPTS_0487	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPTS_0491	COG3423	Transcriptional regulator
YPTS_0493	COG0142	geranyltranstransferase activity
YPTS_0496	COG0697	spore germination
YPTS_0498	COG0642	Histidine kinase
YPTS_0499	COG0745	RESPONSE REGULATOR receiver
YPTS_0500	COG2027	D-alanyl-D-alanine carboxypeptidase
YPTS_0501	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPTS_0502	COG1534	Rna-binding protein
YPTS_0504	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YPTS_0505	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPTS_0507	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPTS_0509	COG0195	Participates in both transcription termination and antitermination
YPTS_0516	COG0513	Belongs to the DEAD box helicase family
YPTS_0520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPTS_0522	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPTS_0527	COG3153	acetyltransferase
YPTS_0531	COG1653	transport
YPTS_0533	COG0395	ABC-type sugar transport system, permease component
YPTS_0534	COG3842	ATPase activity
YPTS_0537	COG0702	epimerase
YPTS_0538	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPTS_0539	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPTS_0540	COG3454	Phosphonate metabolism
YPTS_0541	COG4778	phosphonate C-P lyase system protein PhnL
YPTS_0542	COG4107	phosphonate C-P lyase system protein PhnK
YPTS_0543	COG3627	carbon phosphorus lyase activity
YPTS_0544	COG3626	phosphonate metabolism
YPTS_0545	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPTS_0546	COG3624	Phosphonate C-P lyase system protein PhnG
YPTS_0547	COG2188	Transcriptional regulator
YPTS_0551	COG4608	Belongs to the ABC transporter superfamily
YPTS_0552	COG0444	Belongs to the ABC transporter superfamily
YPTS_0553	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPTS_0554	COG0601	transmembrane transport
YPTS_0556	COG2731	YhcH YjgK YiaL family protein
YPTS_0558	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPTS_0561	COG2927	DNA polymerase III (CHI subunit)
YPTS_0563	COG0795	lipopolysaccharide-transporting ATPase activity
YPTS_0564	COG0795	lipopolysaccharide-transporting ATPase activity
YPTS_0569	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPTS_0569	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_0569	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_0577	COG2390	Transcriptional regulator
YPTS_0579	COG0859	PFAM glycosyl transferase family 9
YPTS_0581	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPTS_0587	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPTS_0588	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPTS_0592	COG3706	GGDEF domain
YPTS_0595	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YPTS_0596	COG0456	acetyltransferase
YPTS_0598	COG2823	Periplasmic or secreted lipoprotein
YPTS_0600	COG4667	esterase of the alpha-beta hydrolase superfamily
YPTS_0601	COG0084	hydrolase, TatD family'
YPTS_0602	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPTS_0603	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPTS_0607	COG3726	membrane protein affecting hemolysin expression
YPTS_0608	COG0560	Phosphoserine phosphatase
YPTS_0612	COG0488	(ABC) transporter
YPTS_0613	COG2885	chlorophyll binding
YPTS_0614	COG2199	diguanylate cyclase activity
YPTS_0617	COG0741	lytic transglycosylase activity
YPTS_0618	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPTS_0621	COG3708	Transcriptional regulator
YPTS_0621	COG2207	Transcriptional regulator
YPTS_0623	COG3045	CreA protein
YPTS_0624	COG0745	RESPONSE REGULATOR receiver
YPTS_0631	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPTS_0634	COG1584	GPR1 FUN34 yaaH family protein
YPTS_0638	COG0583	DNA-binding transcription factor activity
YPTS_0640	COG0196	riboflavin kinase activity
YPTS_0643	COG1047	Peptidyl-prolyl cis-trans
YPTS_0647	COG0505	Belongs to the CarA family
YPTS_0648	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPTS_0650	COG2966	Psort location CytoplasmicMembrane, score
YPTS_0652	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPTS_0658	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPTS_0661	COG0564	pseudouridine synthase activity
YPTS_0671	COG3501	Rhs element vgr protein
YPTS_0678	COG2885	chlorophyll binding
YPTS_0678	COG3047	cAMP biosynthetic process
YPTS_0683	COG0417	DNA replication proofreading
YPTS_0684	COG0586	Pfam SNARE associated Golgi protein
YPTS_0686	COG1178	ABC-type Fe3 transport system permease component
YPTS_0687	COG4143	(ABC) transporter
YPTS_0693	COG2814	Major facilitator Superfamily
YPTS_0701	COG1022	Amp-dependent synthetase and ligase
YPTS_0702	COG0028	Belongs to the TPP enzyme family
YPTS_0704	COG1609	Transcriptional regulator
YPTS_0708	COG3116	cell division
YPTS_0709	COG0768	penicillin binding
YPTS_0710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YPTS_0711	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPTS_0714	COG0772	Belongs to the SEDS family
YPTS_0718	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPTS_0719	COG0849	cell division
YPTS_0720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPTS_0725	COG0494	nUDIX hydrolase
YPTS_0727	COG1943	Transposase
YPTS_0730	COG0237	dephospho-CoA kinase activity
YPTS_0733	COG3328	transposase activity
YPTS_0734	COG1459	type II secretion system
YPTS_0735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPTS_0736	COG4969	Belongs to the N-Me-Phe pilin family
YPTS_0738	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPTS_0739	COG3725	Membrane protein required for beta-lactamase induction
YPTS_0740	COG1113	amino acid transport
YPTS_0742	COG2186	Transcriptional regulator
YPTS_0743	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPTS_0744	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPTS_0745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPTS_0746	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPTS_0748	COG0697	spore germination
YPTS_0753	COG2132	Multicopper oxidase
YPTS_0754	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPTS_0755	COG0288	reversible hydration of carbon dioxide
YPTS_0756	COG1131	(ABC) transporter
YPTS_0757	COG0842	Transport permease protein
YPTS_0758	COG0726	polysaccharide deacetylase
YPTS_0762	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPTS_0763	COG0617	tRNA 3'-terminal CCA addition
YPTS_0765	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YPTS_0767	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPTS_0769	COG1643	Atp-dependent helicase
YPTS_0770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YPTS_0771	COG1120	ATPase activity
YPTS_0772	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPTS_0773	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_0778	COG2860	membrane
YPTS_0782	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPTS_0783	COG2205	protein histidine kinase activity
YPTS_0783	COG3437	response regulator, receiver
YPTS_0783	COG3850	Histidine kinase
YPTS_0783	COG4999	Histidine kinase
YPTS_0784	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YPTS_0785	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPTS_0786	COG3956	TIGRFAM MazG family protein
YPTS_0790	COG0602	queuosine metabolic process
YPTS_0791	COG0720	synthase
YPTS_0801	COG0529	Catalyzes the synthesis of activated sulfate
YPTS_0809	COG1388	LysM domain
YPTS_0809	COG4942	peptidase
YPTS_0810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPTS_0813	COG0698	ribose 5-phosphate isomerase
YPTS_0814	COG1063	alcohol dehydrogenase
YPTS_0815	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_0816	COG2376	Dihydroxyacetone kinase
YPTS_0819	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPTS_0823	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_0824	COG1858	cytochrome C peroxidase
YPTS_0827	COG4771	TonB-dependent receptor
YPTS_0829	COG0024	Methionine aminopeptidase
YPTS_0831	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPTS_0831	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPTS_0832	COG1070	Carbohydrate kinase
YPTS_0833	COG3623	hexulose-6-phosphate isomerase
YPTS_0834	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_0835	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_0836	COG1129	ABC transporter
YPTS_0838	COG1349	DNA-binding transcription factor activity
YPTS_0839	COG0235	Class ii aldolase
YPTS_0840	COG0243	molybdopterin cofactor binding
YPTS_0841	COG0437	4 iron, 4 sulfur cluster binding
YPTS_0842	COG3302	dmso reductase anchor subunit
YPTS_0843	COG3381	protein complex oligomerization
YPTS_0844	COG3038	cytochrome b561
YPTS_0845	COG3783	Cytochrome b(562)
YPTS_0849	COG1129	ABC transporter
YPTS_0850	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_0851	COG3959	Transketolase, thiamine diphosphate binding domain
YPTS_0852	COG3958	Transketolase
YPTS_0853	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPTS_0862	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YPTS_0863	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPTS_0864	COG1238	metal cluster binding
YPTS_0867	COG4536	flavin adenine dinucleotide binding
YPTS_0868	COG4137	Cytochrome C assembly protein
YPTS_0869	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPTS_0874	COG3137	Salt-induced outer membrane protein
YPTS_0875	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPTS_0876	COG3279	Response regulator of the LytR AlgR family
YPTS_0877	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPTS_0878	COG0287	Prephenate dehydrogenase
YPTS_0878	COG1605	Chorismate mutase
YPTS_0881	COG1605	Chorismate mutase
YPTS_0881	COG0077	Prephenate dehydratase
YPTS_0883	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPTS_0884	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPTS_0885	COG0564	pseudouridine synthase activity
YPTS_0887	COG0542	response to heat
YPTS_0891	COG5544	Lipoprotein
YPTS_0892	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPTS_0893	COG1042	CoA-binding domain protein
YPTS_0893	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPTS_0893	COG0045	succinate-CoA ligase (ADP-forming) activity
YPTS_0895	COG3118	belongs to the thioredoxin family
YPTS_0896	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPTS_0897	COG2814	Major facilitator Superfamily
YPTS_0898	COG1566	PFAM secretion protein HlyD family protein
YPTS_0899	COG1846	Transcriptional regulator
YPTS_0901	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPTS_0902	COG2814	Major facilitator Superfamily
YPTS_0911	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPTS_0914	COG0436	Aminotransferase
YPTS_0923	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPTS_0925	COG1960	acyl-CoA dehydrogenase activity
YPTS_0927	COG0121	glutamine amidotransferase
YPTS_0928	COG3034	peptidoglycan biosynthetic process
YPTS_0929	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPTS_0930	COG1805	sodium ion transport
YPTS_0931	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPTS_0935	COG1477	protein flavinylation
YPTS_0939	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPTS_0950	COG2226	methyltransferase
YPTS_0955	COG1940	carbohydrate kinase activity
YPTS_0956	COG0419	ATPase involved in DNA repair
YPTS_0957	COG0420	3'-5' exonuclease activity
YPTS_0958	COG0745	RESPONSE REGULATOR receiver
YPTS_0959	COG5002	protein histidine kinase activity
YPTS_0961	COG1114	Component of the transport system for branched-chain amino acids
YPTS_0963	COG0366	Alpha amylase catalytic
YPTS_0966	COG0450	alkyl hydroperoxide reductase
YPTS_0967	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
YPTS_0970	COG1862	Preprotein translocase
YPTS_0971	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPTS_0972	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPTS_0975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPTS_0975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPTS_0978	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPTS_0979	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPTS_0981	COG0142	geranyltranstransferase activity
YPTS_0985	COG0693	protein deglycase activity
YPTS_0986	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPTS_0988	COG2814	Major facilitator Superfamily
YPTS_0990	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPTS_0991	COG1845	cytochrome c oxidase, subunit III
YPTS_0992	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPTS_0993	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YPTS_0995	COG2223	nitrite transmembrane transporter activity
YPTS_0996	COG3056	Lipoprotein
YPTS_0997	COG0271	Belongs to the BolA IbaG family
YPTS_1002	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPTS_1003	COG0776	regulation of translation
YPTS_1004	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPTS_1005	COG1555	photosystem II stabilization
YPTS_1006	COG0824	Thioesterase
YPTS_1008	COG4533	DNA binding
YPTS_1011	COG1522	sequence-specific DNA binding
YPTS_1012	COG1132	(ABC) transporter
YPTS_1013	COG1132	(ABC) transporter
YPTS_1014	COG0347	Belongs to the P(II) protein family
YPTS_1015	COG0004	ammonium transporteR
YPTS_1017	COG1946	Acyl-CoA thioesterase
YPTS_1018	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPTS_1019	COG3695	enzyme binding
YPTS_1023	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPTS_1025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPTS_1026	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPTS_1027	COG1309	transcriptional regulator
YPTS_1028	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPTS_1029	COG1196	nuclear chromosome segregation
YPTS_1029	COG3264	Mechanosensitive ion channel
YPTS_1035	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPTS_1045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_1050	COG0438	transferase activity, transferring glycosyl groups
YPTS_1053	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_1053	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
YPTS_1058	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPTS_1060	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPTS_1061	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_1062	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPTS_1062	COG4651	solute:proton antiporter activity
YPTS_1063	COG2223	nitrite transmembrane transporter activity
YPTS_1068	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPTS_1069	COG3735	TraB family
YPTS_1070	COG2217	Heavy metal translocating P-type atpase
YPTS_1071	COG0789	Transcriptional regulator
YPTS_1072	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPTS_1073	COG0330	HflC and HflK could
YPTS_1074	COG3118	belongs to the thioredoxin family
YPTS_1075	COG0300	oxidoreductase activity
YPTS_1076	COG2755	lipolytic protein G-D-S-L family
YPTS_1077	COG4181	ATPase activity
YPTS_1078	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPTS_1079	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPTS_1080	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPTS_1082	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPTS_1084	COG2501	S4 domain
YPTS_1092	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPTS_1093	COG4589	Belongs to the CDS family
YPTS_1095	COG2267	carboxylic ester hydrolase activity
YPTS_1096	COG0671	phosphoesterase, PA-phosphatase related
YPTS_1096	COG2453	phosphatase
YPTS_1100	COG0667	Aldo Keto reductase
YPTS_1101	COG0656	L-ascorbic acid biosynthetic process
YPTS_1109	COG1187	pseudouridine synthase activity
YPTS_1110	COG2850	peptidyl-arginine hydroxylation
YPTS_1121	COG3423	Transcriptional regulator
YPTS_1122	COG4953	penicillin-binding protein 1C
YPTS_1123	COG2373	Large extracellular alpha-helical protein
YPTS_1127	COG3962	Belongs to the TPP enzyme family
YPTS_1129	COG0673	inositol 2-dehydrogenase activity
YPTS_1130	COG1879	ABC-type sugar transport system periplasmic component
YPTS_1131	COG1129	ABC transporter
YPTS_1132	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_1133	COG0673	inositol 2-dehydrogenase activity
YPTS_1134	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_1136	COG3718	enzyme involved in inositol metabolism
YPTS_1138	COG5265	(ABC) transporter
YPTS_1142	COG2197	response regulator
YPTS_1143	COG1278	Cold shock
YPTS_1144	COG1278	Cold shock
YPTS_1147	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPTS_1151	COG1686	Belongs to the peptidase S11 family
YPTS_1152	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPTS_1153	COG0772	Belongs to the SEDS family
YPTS_1154	COG0768	penicillin binding
YPTS_1156	COG0799	negative regulation of ribosome biogenesis
YPTS_1158	COG1466	dna polymerase III delta subunit
YPTS_1161	COG2888	peptidyl-tyrosine sulfation
YPTS_1162	COG1126	abc transporter atp-binding protein
YPTS_1163	COG0765	amino acid transport
YPTS_1164	COG0765	amino acid transport
YPTS_1166	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPTS_1167	COG4535	Mg2 and Co2 transporter CorC
YPTS_1169	COG1702	phosphate starvation-inducible protein PhoH
YPTS_1171	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPTS_1173	COG0367	asparagine synthase
YPTS_1174	COG0647	UMP catabolic process
YPTS_1175	COG1940	carbohydrate kinase activity
YPTS_1175	COG1846	Transcriptional regulator
YPTS_1176	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPTS_1178	COG1263	PTS System
YPTS_1178	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_1178	COG2190	(PTS) system
YPTS_1182	COG0735	belongs to the Fur family
YPTS_1187	COG0596	Alpha beta hydrolase
YPTS_1190	COG0582	viral genome integration into host DNA
YPTS_1191	COG2963	transposase activity
YPTS_1192	COG0582	viral genome integration into host DNA
YPTS_1198	COG2003	Belongs to the UPF0758 family
YPTS_1202	COG3596	GTP binding
YPTS_1203	COG4983	Phage plasmid primase, P4 family domain protein
YPTS_1211	COG0582	viral genome integration into host DNA
YPTS_1213	COG2867	negative regulation of translational initiation
YPTS_1215	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPTS_1216	COG0497	DNA recombination
YPTS_1220	COG2009	succinate dehydrogenase
YPTS_1221	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPTS_1222	COG1053	succinate dehydrogenase
YPTS_1224	COG0567	Dehydrogenase, E1 component
YPTS_1225	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPTS_1227	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPTS_1228	COG1271	oxidase subunit
YPTS_1229	COG1294	oxidase, subunit
YPTS_1230	COG4890	Cyd operon protein YbgT
YPTS_1231	COG3790	cyd operon protein YbgE
YPTS_1232	COG0824	Thioesterase
YPTS_1233	COG0811	peptide transport
YPTS_1234	COG0848	biopolymer transport protein
YPTS_1235	COG3064	Membrane
YPTS_1235	COG3064	Membrane
YPTS_1237	COG2885	chlorophyll binding
YPTS_1238	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPTS_1241	COG1230	cation diffusion facilitator family transporter
YPTS_1243	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPTS_1246	COG2017	converts alpha-aldose to the beta-anomer
YPTS_1248	COG1085	galactose-1-phosphate uridylyltransferase
YPTS_1249	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YPTS_1252	COG1119	ATPase activity
YPTS_1253	COG3585	molybdate ion transport
YPTS_1253	COG2005	Transcriptional regulator
YPTS_1255	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPTS_1256	COG4149	molybdate abc transporter
YPTS_1258	COG0561	phosphatase activity
YPTS_1263	COG2226	methyltransferase
YPTS_1264	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPTS_1267	COG4628	conserved protein (DUF2132)
YPTS_1268	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPTS_1270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPTS_1272	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YPTS_1273	COG0314	molybdopterin synthase activity
YPTS_1274	COG0670	Belongs to the BI1 family
YPTS_1278	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPTS_1279	COG0583	DNA-binding transcription factor activity
YPTS_1281	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPTS_1282	COG2211	Major facilitator Superfamily
YPTS_1286	COG1902	pentaerythritol trinitrate reductase activity
YPTS_1289	COG0842	Transport permease protein
YPTS_1290	COG0842	Transport permease protein
YPTS_1291	COG1131	(ABC) transporter
YPTS_1293	COG1309	transcriptional regulator
YPTS_1294	COG0513	Belongs to the DEAD box helicase family
YPTS_1303	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPTS_1305	COG1686	Belongs to the peptidase S11 family
YPTS_1306	COG0277	FAD linked oxidase domain protein
YPTS_1308	COG1403	HNH endonuclease
YPTS_1310	COG2261	transglycosylase associated protein
YPTS_1312	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPTS_1315	COG4807	Protein conserved in bacteria
YPTS_1319	COG1122	ATPase activity
YPTS_1320	COG0410	ABC transporter
YPTS_1323	COG2897	thiosulfate sulfurtransferase activity
YPTS_1324	COG1732	Glycine betaine
YPTS_1325	COG1174	glycine betaine transport
YPTS_1326	COG1125	glycine betaine transport
YPTS_1327	COG1174	glycine betaine transport
YPTS_1328	COG0531	amino acid
YPTS_1329	COG1982	Orn Lys Arg decarboxylase major
YPTS_1331	COG0697	spore germination
YPTS_1336	COG0814	amino acid
YPTS_1339	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPTS_1345	COG0784	Response regulator, receiver
YPTS_1345	COG2205	protein histidine kinase activity
YPTS_1347	COG2198	Histidine kinase
YPTS_1347	COG0642	Histidine kinase
YPTS_1348	COG2223	nitrite transmembrane transporter activity
YPTS_1350	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YPTS_1351	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPTS_1360	COG3395	kinase activity
YPTS_1361	COG0235	Class ii aldolase
YPTS_1362	COG1349	DNA-binding transcription factor activity
YPTS_1363	COG3622	Belongs to the hyi family
YPTS_1367	COG4386	tail sheath protein
YPTS_1375	COG3299	homolog of phage Mu protein gp47
YPTS_1378	COG1737	Transcriptional regulator
YPTS_1380	COG2723	6-phospho-beta-galactosidase activity
YPTS_1385	COG3157	Type VI secretion system effector, Hcp
YPTS_1388	COG3083	sulfuric ester hydrolase activity
YPTS_1389	COG3082	Protein of unknown function (DUF1414)
YPTS_1392	COG1061	Type III restriction enzyme res subunit
YPTS_1393	COG1187	pseudouridine synthase activity
YPTS_1394	COG2814	Major facilitator Superfamily
YPTS_1396	COG4172	Belongs to the ABC transporter superfamily
YPTS_1397	COG4239	(ABC) transporter, permease
YPTS_1398	COG4174	ABC transporter (Permease)
YPTS_1399	COG4166	transmembrane transport
YPTS_1400	COG2200	EAL domain
YPTS_1401	COG0791	NLP P60 protein
YPTS_1402	COG0671	phosphoesterase, PA-phosphatase related
YPTS_1403	COG0523	cobalamin synthesis protein
YPTS_1405	COG2186	Transcriptional regulator
YPTS_1406	COG0246	Mannitol dehydrogenase
YPTS_1411	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_1421	COG1129	ABC transporter
YPTS_1422	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_1423	COG0494	nUDIX hydrolase
YPTS_1425	COG1105	Belongs to the carbohydrate kinase PfkB family
YPTS_1426	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPTS_1426	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPTS_1426	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YPTS_1427	COG3710	Transcriptional regulator
YPTS_1430	COG3121	Chaperone
YPTS_1431	COG3188	usher protein
YPTS_1433	COG2855	membrane
YPTS_1434	COG0583	DNA-binding transcription factor activity
YPTS_1436	COG0833	amino acid
YPTS_1438	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_1440	COG4771	TonB-dependent receptor
YPTS_1441	COG0625	glutathione transferase activity
YPTS_1447	COG2011	ABC-type metal ion transport system permease component
YPTS_1448	COG1686	Belongs to the peptidase S11 family
YPTS_1449	COG0814	amino acid
YPTS_1450	COG1349	DNA-binding transcription factor activity
YPTS_1451	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPTS_1452	COG0671	phosphoesterase, PA-phosphatase related
YPTS_1454	COG0569	domain protein
YPTS_1454	COG2985	domain, Protein
YPTS_1455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPTS_1458	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPTS_1459	COG3842	ATPase activity
YPTS_1460	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPTS_1461	COG1177	transmembrane transport
YPTS_1464	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_1469	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_1470	COG1120	ATPase activity
YPTS_1474	COG4160	amino acid transport
YPTS_1475	COG4215	(ABC) transporter
YPTS_1476	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_1477	COG1126	abc transporter atp-binding protein
YPTS_1478	COG1605	Chorismate mutase
YPTS_1480	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_1481	COG0702	epimerase
YPTS_1482	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPTS_1483	COG0028	Belongs to the TPP enzyme family
YPTS_1484	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPTS_1486	COG2431	L-lysine efflux transmembrane transporter activity
YPTS_1487	COG3593	DNA synthesis involved in DNA repair
YPTS_1489	COG2990	Protein conserved in bacteria
YPTS_1490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPTS_1492	COG1278	Cold shock
YPTS_1494	COG0542	response to heat
YPTS_1495	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YPTS_1497	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPTS_1499	COG0492	ferredoxin-NADP+ reductase activity
YPTS_1501	COG3107	peptidoglycan biosynthetic process
YPTS_1501	COG1674	ftsk spoiiie
YPTS_1503	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPTS_1506	COG2814	Major facilitator Superfamily
YPTS_1507	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPTS_1509	COG1882	Formate acetyltransferase
YPTS_1510	COG2116	formate transmembrane transporter activity
YPTS_1511	COG1944	ATP diphosphatase activity
YPTS_1512	COG0252	asparaginase activity
YPTS_1518	COG0539	negative regulation of cytoplasmic translation
YPTS_1521	COG0658	competence protein
YPTS_1521	COG2333	competence protein COMEC
YPTS_1524	COG5383	Protein conserved in bacteria
YPTS_1525	COG1278	Cold shock
YPTS_1526	COG2835	tetraacyldisaccharide 4'-kinase activity
YPTS_1528	COG3173	Aminoglycoside phosphotransferase
YPTS_1529	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPTS_1530	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
YPTS_1531	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
YPTS_1533	COG2989	Protein conserved in bacteria
YPTS_1534	COG3108	Peptidase M15
YPTS_1535	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPTS_1536	COG1448	Aminotransferase
YPTS_1541	COG0308	aminopeptidase N
YPTS_1542	COG3328	transposase activity
YPTS_1545	COG3217	Mosc domain protein beta barrel domain protein
YPTS_1545	COG0633	Ferredoxin
YPTS_1547	COG0488	(ABC) transporter
YPTS_1548	COG2995	paraquat-inducible protein a
YPTS_1549	COG3008	intermembrane lipid transfer
YPTS_1549	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPTS_1550	COG3009	Protein conserved in bacteria
YPTS_1551	COG3130	regulation of translation
YPTS_1553	COG1943	Transposase
YPTS_1554	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPTS_1557	COG1067	ATP-dependent peptidase activity
YPTS_1559	COG2885	chlorophyll binding
YPTS_1559	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPTS_1561	COG3070	regulator of competence-specific genes
YPTS_1562	COG1289	transmembrane transporter activity
YPTS_1563	COG3304	Inner membrane component domain
YPTS_1564	COG0210	DNA helicase
YPTS_1566	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
YPTS_1567	COG1832	CoA-binding protein
YPTS_1571	COG2920	part of a sulfur-relay system
YPTS_1577	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_1579	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPTS_1580	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPTS_1581	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_1582	COG3425	synthase
YPTS_1584	COG1024	Enoyl-CoA hydratase
YPTS_1585	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_1587	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YPTS_1588	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPTS_1616	COG0488	(ABC) transporter
YPTS_1619	COG0303	'Molybdopterin
YPTS_1622	COG1136	(ABC) transporter
YPTS_1628	COG0583	DNA-binding transcription factor activity
YPTS_1629	COG0477	Major facilitator Superfamily
YPTS_1631	COG2311	Membrane
YPTS_1634	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPTS_1635	COG2949	membrane
YPTS_1638	COG1346	cytolysis
YPTS_1640	COG2814	Major facilitator Superfamily
YPTS_1645	COG0489	protein tyrosine kinase activity
YPTS_1648	COG2982	Protein involved in outer membrane biogenesis
YPTS_1649	COG1253	flavin adenine dinucleotide binding
YPTS_1650	COG4114	ferric iron reductase
YPTS_1651	COG0076	glutamate decarboxylase activity
YPTS_1652	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YPTS_1655	COG1120	ATPase activity
YPTS_1656	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_1657	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPTS_1658	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPTS_1661	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPTS_1662	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPTS_1664	COG0140	phosphoribosyl-ATP diphosphatase activity
YPTS_1664	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPTS_1667	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YPTS_1672	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_1676	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_1677	COG1129	ABC transporter
YPTS_1678	COG0371	Dehydrogenase
YPTS_1680	COG0531	amino acid
YPTS_1681	COG2925	Exonuclease
YPTS_1684	COG1470	cell adhesion involved in biofilm formation
YPTS_1684	COG1388	LysM domain
YPTS_1685	COG2271	Major facilitator Superfamily
YPTS_1686	COG3011	Protein conserved in bacteria
YPTS_1688	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_1690	COG4948	Mandelate Racemase Muconate Lactonizing
YPTS_1694	COG0534	Mate efflux family protein
YPTS_1698	COG3122	Protein conserved in bacteria
YPTS_1708	COG4771	TonB-dependent receptor
YPTS_1709	COG1021	2,3-dihydroxybenzoate-AMP ligase
YPTS_1713	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPTS_1713	COG2226	methyltransferase
YPTS_1713	COG3433	isochorismatase activity
YPTS_1716	COG1132	(ABC) transporter
YPTS_1717	COG2814	Major facilitator Superfamily
YPTS_1718	COG1169	isochorismate synthase
YPTS_1724	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPTS_1728	COG2223	nitrite transmembrane transporter activity
YPTS_1733	COG1132	(ABC) transporter
YPTS_1736	COG2207	Transcriptional regulator
YPTS_1743	COG1113	amino acid transport
YPTS_1747	COG1278	Cold shock
YPTS_1749	COG2226	methyltransferase
YPTS_1751	COG3447	MASE1 domain protein
YPTS_1751	COG5002	protein histidine kinase activity
YPTS_1751	COG5001	Diguanylate cyclase
YPTS_1755	COG3716	PTS system mannose fructose sorbose family IID component
YPTS_1756	COG3715	PTS system
YPTS_1757	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_1757	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_1759	COG1253	flavin adenine dinucleotide binding
YPTS_1760	COG1846	Transcriptional regulator
YPTS_1763	COG1012	belongs to the aldehyde dehydrogenase family
YPTS_1764	COG3384	dioxygenase
YPTS_1766	COG3971	2-oxopent-4-enoate hydratase activity
YPTS_1769	COG2368	4-hydroxyphenylacetate
YPTS_1770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YPTS_1771	COG1760	l-serine dehydratase
YPTS_1776	COG0513	Belongs to the DEAD box helicase family
YPTS_1777	COG3141	response to X-ray
YPTS_1780	COG1770	oligopeptidase
YPTS_1784	COG1528	Iron-storage protein
YPTS_1785	COG2372	response to copper ion
YPTS_1789	COG3328	transposase activity
YPTS_1792	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPTS_1793	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPTS_1796	COG3418	PFAM FlgN family protein
YPTS_1797	COG2747	anti-sigma28 factor FlgM
YPTS_1799	COG1815	bacterial-type flagellum-dependent cell motility
YPTS_1800	COG1558	bacterial-type flagellum-dependent cell motility
YPTS_1801	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPTS_1802	COG1749	Flagellar hook protein flgE
YPTS_1804	COG4786	Flagellar basal body rod
YPTS_1808	COG1256	bacterial-type flagellum assembly
YPTS_1810	COG2390	Transcriptional regulator
YPTS_1811	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_1811	COG3347	Dehydrogenase
YPTS_1813	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_1815	COG1129	ABC transporter
YPTS_1816	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_1817	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_1821	COG1987	bacterial-type flagellum assembly
YPTS_1826	COG1580	Controls the rotational direction of flagella during chemotaxis
YPTS_1828	COG2882	bacterial-type flagellum organization
YPTS_1829	COG1157	protein secretion by the type III secretion system
YPTS_1831	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YPTS_1833	COG1677	Flagellar hook-basal body complex protein FliE
YPTS_1836	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPTS_1837	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPTS_1843	COG1191	sigma factor activity
YPTS_1854	COG0506	proline dehydrogenase activity
YPTS_1854	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPTS_1854	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPTS_1862	COG1113	amino acid transport
YPTS_1865	COG3136	membrane protein required for alginate biosynthesis
YPTS_1867	COG2197	response regulator
YPTS_1897	COG4695	Portal protein
YPTS_1905	COG5002	protein histidine kinase activity
YPTS_1905	COG2176	DNA-directed DNA polymerase activity
YPTS_1919	COG4974	Belongs to the 'phage' integrase family
YPTS_1938	COG2963	transposase activity
YPTS_1950	COG3328	transposase activity
YPTS_1951	COG3328	transposase activity
YPTS_1961	COG0673	inositol 2-dehydrogenase activity
YPTS_1963	COG1175	transmembrane transport
YPTS_1964	COG0395	ABC-type sugar transport system, permease component
YPTS_1966	COG3121	Chaperone
YPTS_1968	COG3188	usher protein
YPTS_1971	COG2205	protein histidine kinase activity
YPTS_1971	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_1973	COG0427	acetyl-CoA hydrolase
YPTS_1974	COG2030	dehydratase
YPTS_1982	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPTS_1983	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPTS_1985	COG1349	DNA-binding transcription factor activity
YPTS_1986	COG2066	Belongs to the glutaminase family
YPTS_1988	COG0672	)-iron permease
YPTS_1992	COG0577	efflux transmembrane transporter activity
YPTS_1992	COG1136	(ABC) transporter
YPTS_1994	COG0577	efflux transmembrane transporter activity
YPTS_1994	COG1136	(ABC) transporter
YPTS_1998	COG0006	proline dipeptidase activity
YPTS_1999	COG0457	Tetratricopeptide repeat
YPTS_2000	COG0726	polysaccharide deacetylase
YPTS_2000	COG1649	PFAM Uncharacterised BCR, COG1649
YPTS_2001	COG1215	transferase activity, transferring glycosyl groups
YPTS_2002	COG3658	cytochrome
YPTS_2005	COG1702	phosphate starvation-inducible protein PhoH
YPTS_2006	COG0387	Pfam Sodium calcium exchanger
YPTS_2007	COG3850	Histidine kinase
YPTS_2008	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPTS_2019	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YPTS_2023	COG0402	S-adenosylhomocysteine deaminase activity
YPTS_2026	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPTS_2027	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_2040	COG0500	methyltransferase
YPTS_2049	COG5002	protein histidine kinase activity
YPTS_2055	COG0012	GTP binding
YPTS_2058	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPTS_2064	COG2890	protein-(glutamine-N5) methyltransferase activity
YPTS_2065	COG3094	Invasion gene expression up-regulator, SirB
YPTS_2066	COG2912	Transglutaminase-like superfamily
YPTS_2068	COG0659	secondary active sulfate transmembrane transporter activity
YPTS_2072	COG3833	ABC-type maltose transport systems, permease component
YPTS_2073	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPTS_2075	COG0584	glycerophosphoryl diester phosphodiesterase
YPTS_2076	COG1940	carbohydrate kinase activity
YPTS_2078	COG3381	protein complex oligomerization
YPTS_2081	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPTS_2083	COG0673	inositol 2-dehydrogenase activity
YPTS_2084	COG0728	peptidoglycan biosynthetic process
YPTS_2089	COG3102	Protein conserved in bacteria
YPTS_2093	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPTS_2094	COG1801	Protein of unknown function DUF72
YPTS_2096	COG0494	nUDIX hydrolase
YPTS_2101	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPTS_2103	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPTS_2104	COG0739	heme binding
YPTS_2105	COG1560	Kdo2-lipid A biosynthetic process
YPTS_2107	COG0469	pyruvate kinase activity
YPTS_2108	COG1737	Transcriptional regulator
YPTS_2109	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPTS_2111	COG0800	Aldolase
YPTS_2114	COG0251	oxidation-reduction process
YPTS_2115	COG1199	ATP-dependent helicase activity
YPTS_2117	COG3065	identical protein binding
YPTS_2118	COG0318	PFAM AMP-dependent synthetase and ligase
YPTS_2119	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPTS_2120	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YPTS_2121	COG2894	cell division
YPTS_2124	COG2951	lytic endotransglycosylase activity
YPTS_2125	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPTS_2128	COG1104	cysteine desulfurase activity
YPTS_2135	COG2719	SpoVR family
YPTS_2137	COG2814	Major facilitator Superfamily
YPTS_2139	COG0583	DNA-binding transcription factor activity
YPTS_2143	COG2766	serine protein kinase
YPTS_2144	COG3713	MltA-interacting MipA family protein
YPTS_2148	COG3139	Protein of unknown function (DUF1315)
YPTS_2149	COG1335	isochorismatase
YPTS_2150	COG0252	asparaginase activity
YPTS_2151	COG0616	signal peptide processing
YPTS_2152	COG0778	Nitroreductase
YPTS_2155	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPTS_2157	COG0494	nUDIX hydrolase
YPTS_2158	COG0708	Exodeoxyribonuclease III
YPTS_2160	COG0583	DNA-binding transcription factor activity
YPTS_2163	COG0788	formyltetrahydrofolate deformylase activity
YPTS_2165	COG0745	RESPONSE REGULATOR receiver
YPTS_2170	COG1435	thymidine kinase activity
YPTS_2171	COG1454	alcohol dehydrogenase
YPTS_2171	COG1012	belongs to the aldehyde dehydrogenase family
YPTS_2172	COG2095	MarC family integral membrane protein
YPTS_2174	COG0601	transmembrane transport
YPTS_2175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPTS_2176	COG0444	Belongs to the ABC transporter superfamily
YPTS_2177	COG4608	Belongs to the ABC transporter superfamily
YPTS_2186	COG2350	Protein conserved in bacteria
YPTS_2188	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPTS_2189	COG1607	acyl-coa hydrolase
YPTS_2194	COG3047	cAMP biosynthetic process
YPTS_2198	COG0135	phosphoribosylanthranilate isomerase activity
YPTS_2198	COG0134	indole-3-glycerol-phosphate synthase activity
YPTS_2200	COG0512	Glutamine amidotransferase of anthranilate synthase
YPTS_2203	COG0009	L-threonylcarbamoyladenylate synthase
YPTS_2204	COG1187	pseudouridine synthase activity
YPTS_2206	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_2207	COG0616	signal peptide processing
YPTS_2210	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPTS_2211	COG0583	DNA-binding transcription factor activity
YPTS_2213	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YPTS_2214	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YPTS_2215	COG0671	phosphoesterase, PA-phosphatase related
YPTS_2216	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPTS_2217	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPTS_2220	COG0023	Translation Initiation Factor
YPTS_2224	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPTS_2225	COG2879	small protein
YPTS_2226	COG1966	Carbon starvation protein
YPTS_2228	COG2271	Major facilitator Superfamily
YPTS_2229	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPTS_2230	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPTS_2232	COG4659	FMN binding
YPTS_2234	COG2207	Transcriptional regulator
YPTS_2234	COG3708	Transcriptional regulator
YPTS_2241	COG2274	protein secretion by the type I secretion system
YPTS_2244	COG1879	ABC-type sugar transport system periplasmic component
YPTS_2246	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_2248	COG0673	inositol 2-dehydrogenase activity
YPTS_2249	COG0385	Bile acid
YPTS_2253	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_2253	COG1263	PTS System
YPTS_2253	COG2190	(PTS) system
YPTS_2255	COG5339	Protein conserved in bacteria
YPTS_2256	COG1482	cell wall glycoprotein biosynthetic process
YPTS_2257	COG0114	fumarate hydratase activity
YPTS_2259	COG2814	Major facilitator Superfamily
YPTS_2260	COG0583	DNA-binding transcription factor activity
YPTS_2261	COG1940	carbohydrate kinase activity
YPTS_2262	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPTS_2266	COG4221	oxidoreductase activity
YPTS_2267	COG3284	Transcriptional regulator
YPTS_2269	COG4221	oxidoreductase activity
YPTS_2270	COG3284	Transcriptional regulator
YPTS_2271	COG1012	belongs to the aldehyde dehydrogenase family
YPTS_2276	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPTS_2277	COG1757	Na H antiporter
YPTS_2279	COG1609	Transcriptional regulator
YPTS_2281	COG1879	ABC-type sugar transport system periplasmic component
YPTS_2282	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_2283	COG1129	ABC transporter
YPTS_2286	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPTS_2287	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPTS_2289	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPTS_2294	COG0028	Belongs to the TPP enzyme family
YPTS_2295	COG0440	acetolactate synthase activity
YPTS_2296	COG1011	Hydrolase
YPTS_2299	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPTS_2300	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPTS_2301	COG0589	response to stress
YPTS_2302	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPTS_2303	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPTS_2305	COG0531	amino acid
YPTS_2307	COG0745	RESPONSE REGULATOR receiver
YPTS_2308	COG2205	protein histidine kinase activity
YPTS_2309	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPTS_2312	COG3038	cytochrome b561
YPTS_2314	COG3591	Belongs to the peptidase S1B family
YPTS_2317	COG1643	Atp-dependent helicase
YPTS_2319	COG2390	Transcriptional regulator
YPTS_2320	COG0246	Mannitol dehydrogenase
YPTS_2321	COG3784	Protein of unknown function (DUF1318)
YPTS_2323	COG2911	Protein conserved in bacteria
YPTS_2324	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPTS_2325	COG3187	Heat shock protein
YPTS_2326	COG3042	response to heat
YPTS_2327	COG1285	pathogenesis
YPTS_2329	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPTS_2329	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPTS_2329	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPTS_2329	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPTS_2331	COG0657	acetylesterase activity
YPTS_2331	COG2755	lipolytic protein G-D-S-L family
YPTS_2335	COG4166	transmembrane transport
YPTS_2336	COG2866	Carboxypeptidase
YPTS_2337	COG4948	Mandelate Racemase Muconate Lactonizing
YPTS_2338	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPTS_2343	COG3106	COG3106 Predicted ATPase
YPTS_2345	COG1983	PspC domain protein
YPTS_2347	COG1842	Phage shock protein A
YPTS_2348	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPTS_2349	COG4166	transmembrane transport
YPTS_2350	COG4168	peptide transport system, permease
YPTS_2351	COG4171	peptide transport system, permease
YPTS_2353	COG4172	Belongs to the ABC transporter superfamily
YPTS_2354	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPTS_2354	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPTS_2355	COG3104	oligopeptide transport
YPTS_2358	COG0625	glutathione transferase activity
YPTS_2362	COG4989	oxidoreductase activity
YPTS_2363	COG3313	Fe-S protein
YPTS_2364	COG2194	sulfuric ester hydrolase activity
YPTS_2365	COG1309	transcriptional regulator
YPTS_2366	COG1902	pentaerythritol trinitrate reductase activity
YPTS_2368	COG0346	lactoylglutathione lyase activity
YPTS_2370	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPTS_2372	COG0791	NLP P60 protein
YPTS_2373	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPTS_2375	COG0583	DNA-binding transcription factor activity
YPTS_2376	COG2814	Major facilitator Superfamily
YPTS_2377	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPTS_2378	COG0307	riboflavin synthase, alpha
YPTS_2381	COG4238	major outer membrane lipoprotein
YPTS_2382	COG1388	LysM domain
YPTS_2382	COG1376	ErfK ybiS ycfS ynhG family protein
YPTS_2385	COG0719	Fe-S assembly protein
YPTS_2386	COG0396	ATPase activity
YPTS_2387	COG0719	Fe-S assembly protein
YPTS_2388	COG0316	Belongs to the HesB IscA family
YPTS_2389	COG2050	protein possibly involved in aromatic compounds catabolism
YPTS_2390	COG0277	FAD linked oxidase domain protein
YPTS_2390	COG0247	lactate metabolic process
YPTS_2391	COG0628	permease
YPTS_2393	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPTS_2393	COG0574	Belongs to the PEP-utilizing enzyme family
YPTS_2398	COG0791	NLP P60 protein
YPTS_2406	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
YPTS_2407	COG0386	Belongs to the glutathione peroxidase family
YPTS_2410	COG0776	regulation of translation
YPTS_2417	COG4249	Peptidase C14 caspase catalytic subunit p20
YPTS_2421	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPTS_2422	COG1121	(ABC) transporter
YPTS_2423	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPTS_2424	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPTS_2428	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPTS_2429	COG1917	Cupin 2, conserved barrel domain protein
YPTS_2431	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_2433	COG1175	transmembrane transport
YPTS_2434	COG0395	ABC-type sugar transport system, permease component
YPTS_2435	COG3842	ATPase activity
YPTS_2436	COG1653	transport
YPTS_2437	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPTS_2438	COG1988	membrane-bound metal-dependent
YPTS_2440	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPTS_2442	COG0823	Involved in the tonB-independent uptake of proteins
YPTS_2443	COG2814	Major facilitator Superfamily
YPTS_2444	COG3121	Chaperone
YPTS_2447	COG3121	Chaperone
YPTS_2448	COG3539	Fimbrial protein
YPTS_2451	COG0793	Belongs to the peptidase S41A family
YPTS_2453	COG1956	GAF domain-containing protein
YPTS_2454	COG2995	paraquat-inducible protein a
YPTS_2455	COG3008	intermembrane lipid transfer
YPTS_2459	COG3121	Chaperone
YPTS_2470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPTS_2473	COG5295	Hep Hag repeat protein
YPTS_2473	COG5295	Hep Hag repeat protein
YPTS_2474	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPTS_2475	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPTS_2476	COG0745	RESPONSE REGULATOR receiver
YPTS_2478	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPTS_2479	COG0840	transmembrane signaling receptor activity
YPTS_2480	COG0840	transmembrane signaling receptor activity
YPTS_2483	COG0835	chemotaxis
YPTS_2484	COG0643	Histidine kinase
YPTS_2484	COG2198	Histidine kinase
YPTS_2485	COG1360	Flagellar Motor Protein
YPTS_2490	COG1285	pathogenesis
YPTS_2491	COG0840	transmembrane signaling receptor activity
YPTS_2493	COG1278	Cold shock
YPTS_2496	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_2496	COG3321	synthase
YPTS_2496	COG0604	alcohol dehydrogenase
YPTS_2500	COG1522	sequence-specific DNA binding
YPTS_2505	COG1733	regulation of RNA biosynthetic process
YPTS_2506	COG0702	epimerase
YPTS_2507	COG0840	transmembrane signaling receptor activity
YPTS_2510	COG0538	isocitrate dehydrogenase activity
YPTS_2511	COG1187	pseudouridine synthase activity
YPTS_2515	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YPTS_2518	COG0745	RESPONSE REGULATOR receiver
YPTS_2520	COG2850	peptidyl-arginine hydroxylation
YPTS_2522	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YPTS_2524	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPTS_2526	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPTS_2527	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YPTS_2528	COG3134	Outer membrane lipoprotein
YPTS_2531	COG1252	NADH dehydrogenase
YPTS_2536	COG5633	Lipoprotein
YPTS_2537	COG0537	adenosine 5'-monophosphoramidase activity
YPTS_2538	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPTS_2545	COG4695	Portal protein
YPTS_2551	COG1263	PTS System
YPTS_2551	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_2552	COG0084	hydrolase, TatD family'
YPTS_2553	COG0470	DNA polymerase III
YPTS_2555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPTS_2556	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPTS_2557	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPTS_2559	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_2563	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YPTS_2564	COG1399	metal-binding, possibly nucleic acid-binding protein
YPTS_2566	COG0564	pseudouridine synthase activity
YPTS_2568	COG1530	ribonuclease E activity
YPTS_2569	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YPTS_2575	COG3328	transposase activity
YPTS_2576	COG2197	response regulator
YPTS_2578	COG0628	permease
YPTS_2582	COG1560	Kdo2-lipid A biosynthetic process
YPTS_2584	COG3104	oligopeptide transport
YPTS_2585	COG5645	(Lipo)protein
YPTS_2586	COG2943	transferase activity, transferring hexosyl groups
YPTS_2587	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
YPTS_2592	COG3916	Acyl-homoserine-lactone synthase
YPTS_2593	COG2771	luxR family
YPTS_2594	COG0583	DNA-binding transcription factor activity
YPTS_2596	COG0477	Major facilitator Superfamily
YPTS_2598	COG0667	Aldo Keto reductase
YPTS_2603	COG1203	CRISPR-associated helicase, Cas3
YPTS_2604	COG1518	maintenance of DNA repeat elements
YPTS_2605	COG0668	transmembrane transport
YPTS_2609	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPTS_2610	COG0395	ABC-type sugar transport system, permease component
YPTS_2613	COG1609	Transcriptional regulator
YPTS_2615	COG3842	ATPase activity
YPTS_2618	COG3210	domain, Protein
YPTS_2621	COG3210	domain, Protein
YPTS_2622	COG2831	hemolysin activation secretion protein
YPTS_2623	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPTS_2624	COG4638	Rieske (2fe-2S)
YPTS_2625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPTS_2627	COG0473	3-isopropylmalate dehydrogenase activity
YPTS_2628	COG0583	DNA-binding transcription factor activity
YPTS_2629	COG1609	Transcriptional regulator
YPTS_2630	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_2631	COG1129	ABC transporter
YPTS_2632	COG1879	ABC-type sugar transport system periplasmic component
YPTS_2633	COG1063	alcohol dehydrogenase
YPTS_2637	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPTS_2643	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_2644	COG0765	amino acid transport
YPTS_2645	COG1126	abc transporter atp-binding protein
YPTS_2649	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPTS_2652	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPTS_2655	COG1169	isochorismate synthase
YPTS_2657	COG4575	ribosome binding
YPTS_2660	COG0129	dihydroxy-acid dehydratase activity
YPTS_2663	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPTS_2664	COG1609	Transcriptional regulator
YPTS_2666	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_2667	COG3265	gluconokinase activity
YPTS_2668	COG2731	YhcH YjgK YiaL family protein
YPTS_2671	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPTS_2672	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPTS_2674	COG0839	Belongs to the complex I subunit 6 family
YPTS_2677	COG1034	ATP synthesis coupled electron transport
YPTS_2679	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
YPTS_2681	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPTS_2683	COG0583	DNA-binding transcription factor activity
YPTS_2684	COG0436	Aminotransferase
YPTS_2687	COG0490	domain, Protein
YPTS_2687	COG0471	metal ion transport
YPTS_2688	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPTS_2692	COG0857	belongs to the CobB CobQ family
YPTS_2692	COG0280	phosphate acetyltransferase
YPTS_2693	COG1609	Transcriptional regulator
YPTS_2696	COG3037	sugar-specific permease SgaT UlaA
YPTS_2697	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YPTS_2698	COG0622	Phosphoesterase
YPTS_2700	COG1090	epimerase
YPTS_2701	COG4598	ABC transporter
YPTS_2702	COG4160	amino acid transport
YPTS_2703	COG4215	(ABC) transporter
YPTS_2704	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_2706	COG0163	prenyltransferase activity
YPTS_2707	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPTS_2708	COG1286	toxin biosynthetic process
YPTS_2709	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPTS_2710	COG0285	dihydrofolate synthase activity
YPTS_2712	COG0586	Pfam SNARE associated Golgi protein
YPTS_2714	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPTS_2717	COG0697	spore germination
YPTS_2720	COG1794	racemase activity, acting on amino acids and derivatives
YPTS_2721	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPTS_2724	COG3101	peptidyl-lysine hydroxylation
YPTS_2725	COG0730	response to heat
YPTS_2728	COG2890	protein-(glutamine-N5) methyltransferase activity
YPTS_2730	COG2062	phosphohistidine phosphatase, SixA
YPTS_2735	COG3691	Protein conserved in bacteria
YPTS_2738	COG3088	subunit of a heme lyase
YPTS_2738	COG4235	cytochrome complex assembly
YPTS_2739	COG4235	cytochrome complex assembly
YPTS_2739	COG3088	subunit of a heme lyase
YPTS_2740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPTS_2741	COG1138	Cytochrome C-type biogenesis protein
YPTS_2743	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPTS_2744	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPTS_2745	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPTS_2748	COG1704	LemA family
YPTS_2750	COG2824	Alkylphosphonate utilization operon protein PhnA
YPTS_2756	COG3501	Rhs element vgr protein
YPTS_2765	COG3188	usher protein
YPTS_2766	COG3121	Chaperone
YPTS_2779	COG2951	lytic endotransglycosylase activity
YPTS_2787	COG0243	molybdopterin cofactor binding
YPTS_2788	COG0437	4 iron, 4 sulfur cluster binding
YPTS_2789	COG3302	dmso reductase anchor subunit
YPTS_2790	COG3381	protein complex oligomerization
YPTS_2796	COG3038	cytochrome b561
YPTS_2797	COG0436	Aminotransferase
YPTS_2802	COG0667	Aldo Keto reductase
YPTS_2805	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPTS_2810	COG3530	Putative quorum-sensing-regulated virulence factor
YPTS_2813	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YPTS_2814	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YPTS_2815	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_2817	COG2190	(PTS) system
YPTS_2818	COG2205	protein histidine kinase activity
YPTS_2819	COG0745	RESPONSE REGULATOR receiver
YPTS_2820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPTS_2823	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPTS_2825	COG0006	proline dipeptidase activity
YPTS_2826	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPTS_2828	COG3850	Histidine kinase
YPTS_2828	COG5002	protein histidine kinase activity
YPTS_2829	COG0745	RESPONSE REGULATOR receiver
YPTS_2831	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YPTS_2833	COG4208	sulfate ABC transporter
YPTS_2834	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPTS_2835	COG4150	thiosulfate binding
YPTS_2837	COG1737	Transcriptional regulator
YPTS_2838	COG2731	YhcH YjgK YiaL family protein
YPTS_2840	COG4886	Leucine-rich repeat (LRR) protein
YPTS_2843	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPTS_2844	COG2837	iron assimilation
YPTS_2846	COG3111	PFAM Bacterial OB fold (BOF) protein
YPTS_2849	COG0456	acetyltransferase
YPTS_2862	COG3005	denitrification pathway
YPTS_2863	COG3043	anaerobic respiration
YPTS_2865	COG3062	negative regulation of establishment of protein localization
YPTS_2866	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPTS_2866	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPTS_2867	COG2197	response regulator
YPTS_2869	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPTS_2871	COG1988	membrane-bound metal-dependent
YPTS_2872	COG0641	radical SAM
YPTS_2873	COG3119	arylsulfatase activity
YPTS_2874	COG3842	ATPase activity
YPTS_2875	COG1175	transmembrane transport
YPTS_2876	COG1840	ABC-type Fe3 transport system, periplasmic component
YPTS_2878	COG1393	Belongs to the ArsC family
YPTS_2880	COG1876	peptidase activity
YPTS_2885	COG2321	neutral zinc metallopeptidase
YPTS_2888	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPTS_2890	COG2716	regulation of RNA biosynthetic process
YPTS_2891	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPTS_2894	COG0628	permease
YPTS_2895	COG4783	chaperone-mediated protein folding
YPTS_2896	COG1393	Belongs to the ArsC family
YPTS_2898	COG2233	PERMEase
YPTS_2901	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPTS_2902	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPTS_2905	COG0581	inorganic phosphate transmembrane transporter activity
YPTS_2907	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPTS_2908	COG0248	Ppx GppA phosphatase
YPTS_2910	COG2239	Acts as a magnesium transporter
YPTS_2911	COG0443	Heat shock 70 kDa protein
YPTS_2913	COG1177	transmembrane transport
YPTS_2914	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPTS_2916	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPTS_2918	COG3842	ATPase activity
YPTS_2923	COG2205	protein histidine kinase activity
YPTS_2924	COG0745	RESPONSE REGULATOR receiver
YPTS_2925	COG3422	double-strand break repair
YPTS_2941	COG0516	GMP reductase activity
YPTS_2941	COG0517	IMP dehydrogenase activity
YPTS_2944	COG1645	bacterial-type flagellum-dependent swarming motility
YPTS_2947	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPTS_2948	COG2976	Protein conserved in bacteria
YPTS_2957	COG3468	outer membrane autotransporter barrel domain protein
YPTS_2958	COG3468	outer membrane autotransporter barrel domain protein
YPTS_2961	COG2975	iron-sulfur cluster assembly
YPTS_2962	COG0633	Ferredoxin
YPTS_2966	COG0822	iron-sulfur transferase activity
YPTS_2967	COG1104	cysteine desulfurase activity
YPTS_2970	COG0483	inositol monophosphate 1-phosphatase activity
YPTS_2971	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPTS_2972	COG3683	transport system, periplasmic component
YPTS_2973	COG3711	transcriptional antiterminator
YPTS_2974	COG2814	Major facilitator Superfamily
YPTS_2979	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPTS_2979	COG1017	nitric oxide dioxygenase activity
YPTS_2980	COG2188	Transcriptional regulator
YPTS_2981	COG0347	Belongs to the P(II) protein family
YPTS_2982	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPTS_2982	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPTS_2984	COG2204	response regulator
YPTS_2985	COG3170	Tfp pilus assembly protein FimV
YPTS_2986	COG2205	protein histidine kinase activity
YPTS_2992	COG0590	tRNA wobble adenosine to inosine editing
YPTS_2993	COG0560	Phosphoserine phosphatase
YPTS_2995	COG1737	Transcriptional regulator
YPTS_2996	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPTS_3002	COG0681	Belongs to the peptidase S26 family
YPTS_3005	COG3086	response to oxidative stress
YPTS_3006	COG3026	antisigma factor binding
YPTS_3007	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
YPTS_3009	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPTS_3011	COG0513	Belongs to the DEAD box helicase family
YPTS_3022	COG1984	allophanate hydrolase subunit 2
YPTS_3023	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YPTS_3025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPTS_3026	COG5212	phosphodiesterase
YPTS_3028	COG3272	Protein of unknown function (DUF1722)
YPTS_3034	COG2205	protein histidine kinase activity
YPTS_3035	COG0745	RESPONSE REGULATOR receiver
YPTS_3039	COG0033	Phosphoglucomutase
YPTS_3040	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPTS_3044	COG1917	Cupin 2, conserved barrel domain protein
YPTS_3044	COG2169	Transcriptional regulator
YPTS_3045	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPTS_3046	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPTS_3047	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPTS_3049	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPTS_3050	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPTS_3052	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPTS_3053	COG4413	Urea transporter
YPTS_3055	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPTS_3062	COG1124	(ABC) transporter
YPTS_3063	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YPTS_3064	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPTS_3066	COG0747	negative chemotaxis
YPTS_3067	COG1278	Cold shock
YPTS_3075	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPTS_3076	COG4175	Glycine betaine
YPTS_3077	COG4176	ABC-type proline glycine betaine transport system permease component
YPTS_3078	COG2113	Glycine betaine
YPTS_3081	COG1953	Uracil, thiamine, allantoin
YPTS_3082	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YPTS_3084	COG2226	methyltransferase
YPTS_3086	COG0741	lytic transglycosylase activity
YPTS_3086	COG1388	LysM domain
YPTS_3089	COG0656	L-ascorbic acid biosynthetic process
YPTS_3092	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPTS_3094	COG2011	ABC-type metal ion transport system permease component
YPTS_3095	COG1464	Belongs to the NlpA lipoprotein family
YPTS_3097	COG1720	tRNA m6t6A37 methyltransferase activity
YPTS_3099	COG3015	lipoprotein NlpE involved in copper resistance
YPTS_3101	COG4681	YaeQ
YPTS_3103	COG4568	rho-dependent transcription termination
YPTS_3106	COG0346	lactoylglutathione lyase activity
YPTS_3108	COG0587	DNA-directed DNA polymerase activity
YPTS_3110	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPTS_3114	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
YPTS_3116	COG0750	zinc metalloprotease
YPTS_3117	COG0575	Belongs to the CDS family
YPTS_3118	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YPTS_3124	COG0024	Methionine aminopeptidase
YPTS_3129	COG0564	pseudouridine synthase activity
YPTS_3130	COG3098	single-species biofilm formation
YPTS_3134	COG1611	Belongs to the LOG family
YPTS_3137	COG2363	Small membrane protein
YPTS_3138	COG0583	DNA-binding transcription factor activity
YPTS_3140	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPTS_3141	COG2166	iron-sulfur cluster assembly
YPTS_3142	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPTS_3143	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPTS_3144	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPTS_3146	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YPTS_3147	COG1074	ATP-dependent DNA helicase activity
YPTS_3149	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPTS_3160	COG0667	Aldo Keto reductase
YPTS_3166	COG1609	Transcriptional regulator
YPTS_3167	COG0019	diaminopimelate decarboxylase activity
YPTS_3168	COG0583	DNA-binding transcription factor activity
YPTS_3169	COG2814	Major facilitator Superfamily
YPTS_3173	COG0840	transmembrane signaling receptor activity
YPTS_3190	COG0288	reversible hydration of carbon dioxide
YPTS_3195	COG3119	arylsulfatase activity
YPTS_3196	COG1349	DNA-binding transcription factor activity
YPTS_3198	COG2222	sugar isomerase
YPTS_3199	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_3200	COG3715	PTS system
YPTS_3201	COG3716	PTS system mannose fructose sorbose family IID component
YPTS_3202	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_3204	COG1028	Short-chain dehydrogenase reductase Sdr
YPTS_3206	COG0641	radical SAM
YPTS_3207	COG3119	arylsulfatase activity
YPTS_3210	COG0191	fructose-bisphosphate aldolase activity
YPTS_3214	COG2271	Major facilitator Superfamily
YPTS_3218	COG1263	PTS System
YPTS_3218	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_3219	COG1874	Beta-galactosidase
YPTS_3220	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPTS_3221	COG3833	ABC-type maltose transport systems, permease component
YPTS_3222	COG1175	transmembrane transport
YPTS_3223	COG2182	Extracellular solute-binding protein
YPTS_3225	COG1129	ABC transporter
YPTS_3226	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_3227	COG1879	ABC-type sugar transport system periplasmic component
YPTS_3229	COG0791	NLP P60 protein
YPTS_3230	COG1695	Transcriptional regulator
YPTS_3247	COG2944	sequence-specific DNA binding
YPTS_3253	COG4974	Belongs to the 'phage' integrase family
YPTS_3268	COG4695	Portal protein
YPTS_3293	COG0582	viral genome integration into host DNA
YPTS_3296	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPTS_3297	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPTS_3298	COG4974	Belongs to the 'phage' integrase family
YPTS_3299	COG0716	FMN binding
YPTS_3300	COG4452	Inner membrane protein CreD
YPTS_3301	COG2205	protein histidine kinase activity
YPTS_3302	COG0745	RESPONSE REGULATOR receiver
YPTS_3304	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
YPTS_3307	COG1272	protein, Hemolysin III
YPTS_3309	COG5295	Hep Hag repeat protein
YPTS_3315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPTS_3316	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPTS_3317	COG0006	proline dipeptidase activity
YPTS_3320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPTS_3321	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPTS_3322	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YPTS_3327	COG0191	fructose-bisphosphate aldolase activity
YPTS_3330	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPTS_3331	COG0501	Belongs to the peptidase M48B family
YPTS_3333	COG1166	arginine decarboxylase activity
YPTS_3337	COG2356	endonuclease I
YPTS_3339	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPTS_3340	COG0189	ligase activity
YPTS_3343	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPTS_3345	COG2805	Type II/IV secretion system protein
YPTS_3346	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPTS_3347	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPTS_3349	COG0762	integral membrane protein
YPTS_3351	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YPTS_3352	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPTS_3353	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPTS_3353	COG3064	Membrane
YPTS_3353	COG1073	alpha beta
YPTS_3355	COG2066	Belongs to the glutaminase family
YPTS_3356	COG3171	Protein conserved in bacteria
YPTS_3358	COG1194	a g-specific adenine glycosylase
YPTS_3363	COG4774	siderophore transport
YPTS_3364	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_3365	COG1129	ABC transporter
YPTS_3366	COG1879	ABC-type sugar transport system periplasmic component
YPTS_3367	COG1982	Orn Lys Arg decarboxylase major
YPTS_3394	COG3916	Acyl-homoserine-lactone synthase
YPTS_3395	COG2771	luxR family
YPTS_3404	COG2211	Major facilitator Superfamily
YPTS_3406	COG1609	Transcriptional regulator
YPTS_3407	COG0471	metal ion transport
YPTS_3419	COG3209	COG3209 Rhs family protein
YPTS_3421	COG3501	Rhs element vgr protein
YPTS_3424	COG2610	gluconate transmembrane transporter activity
YPTS_3428	COG1132	(ABC) transporter
YPTS_3434	COG3433	isochorismatase activity
YPTS_3434	COG2226	methyltransferase
YPTS_3434	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPTS_3435	COG3433	isochorismatase activity
YPTS_3435	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPTS_3435	COG2226	methyltransferase
YPTS_3436	COG4771	TonB-dependent receptor
YPTS_3437	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPTS_3438	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YPTS_3445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPTS_3446	COG3300	MHYT domain
YPTS_3446	COG5001	Diguanylate cyclase
YPTS_3448	COG2801	Transposase and inactivated derivatives
YPTS_3449	COG3133	Outer membrane lipoprotein
YPTS_3454	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YPTS_3455	COG1191	sigma factor activity
YPTS_3460	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
YPTS_3461	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YPTS_3462	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
YPTS_3463	COG3710	Transcriptional regulator
YPTS_3467	COG1256	bacterial-type flagellum assembly
YPTS_3471	COG4786	Flagellar basal body rod
YPTS_3472	COG4787	bacterial-type flagellum-dependent cell motility
YPTS_3473	COG1749	Flagellar hook protein flgE
YPTS_3474	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPTS_3475	COG1558	bacterial-type flagellum-dependent cell motility
YPTS_3476	COG1815	bacterial-type flagellum-dependent cell motility
YPTS_3477	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPTS_3486	COG2204	response regulator
YPTS_3490	COG1987	bacterial-type flagellum assembly
YPTS_3491	COG1684	flagellar biosynthetic protein fliR
YPTS_3492	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPTS_3497	COG4592	Periplasmic binding protein
YPTS_3503	COG3469	chitinase activity
YPTS_3504	COG3397	chitin binding
YPTS_3510	COG4964	Belongs to the GSP D family
YPTS_3522	COG0848	biopolymer transport protein
YPTS_3523	COG0811	peptide transport
YPTS_3524	COG0626	cystathionine gamma-synthase activity
YPTS_3525	COG0586	Pfam SNARE associated Golgi protein
YPTS_3526	COG2207	Transcriptional regulator
YPTS_3527	COG1979	alcohol dehydrogenase
YPTS_3528	COG0656	L-ascorbic acid biosynthetic process
YPTS_3530	COG2132	Multicopper oxidase
YPTS_3532	COG0204	Acyl-transferase
YPTS_3533	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPTS_3534	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPTS_3535	COG0583	DNA-binding transcription factor activity
YPTS_3536	COG0187	DNA topoisomerase II activity
YPTS_3537	COG3150	esterase
YPTS_3538	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YPTS_3539	COG3151	Protein conserved in bacteria
YPTS_3540	COG0494	nUDIX hydrolase
YPTS_3541	COG1538	Outer membrane efflux protein
YPTS_3544	COG0754	glutathionylspermidine amidase activity
YPTS_3545	COG3384	dioxygenase
YPTS_3549	COG0531	amino acid
YPTS_3552	COG3025	triphosphatase activity
YPTS_3553	COG4991	sh3 domain protein
YPTS_3557	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPTS_3561	COG0358	DNA primase activity
YPTS_3562	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPTS_3569	COG5301	cellulose 1,4-beta-cellobiosidase activity
YPTS_3587	COG4695	Portal protein
YPTS_3598	COG4974	Belongs to the 'phage' integrase family
YPTS_3611	COG0251	oxidation-reduction process
YPTS_3619	COG1289	transmembrane transporter activity
YPTS_3623	COG0395	ABC-type sugar transport system, permease component
YPTS_3625	COG1653	transport
YPTS_3626	COG1609	Transcriptional regulator
YPTS_3627	COG3459	Glycosyltransferase 36 associated
YPTS_3628	COG3842	ATPase activity
YPTS_3632	COG3210	domain, Protein
YPTS_3641	COG3210	domain, Protein
YPTS_3643	COG3210	domain, Protein
YPTS_3645	COG3210	domain, Protein
YPTS_3646	COG2831	hemolysin activation secretion protein
YPTS_3647	COG4245	von Willebrand factor, type A
YPTS_3649	COG4245	von Willebrand factor, type A
YPTS_3650	COG4245	von Willebrand factor, type A
YPTS_3653	COG3247	response to pH
YPTS_3654	COG1902	pentaerythritol trinitrate reductase activity
YPTS_3654	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPTS_3657	COG1451	nucleotide metabolic process
YPTS_3658	COG0673	inositol 2-dehydrogenase activity
YPTS_3661	COG2721	sulfolactate sulfo-lyase activity
YPTS_3662	COG0246	Mannitol dehydrogenase
YPTS_3664	COG2271	Major facilitator Superfamily
YPTS_3667	COG0586	Pfam SNARE associated Golgi protein
YPTS_3670	COG4575	ribosome binding
YPTS_3671	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPTS_3673	COG2259	Doxx family
YPTS_3674	COG0435	Glutathione S-transferase
YPTS_3675	COG0583	DNA-binding transcription factor activity
YPTS_3676	COG1741	Belongs to the pirin family
YPTS_3677	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPTS_3681	COG2823	Periplasmic or secreted lipoprotein
YPTS_3683	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YPTS_3684	COG2198	Histidine kinase
YPTS_3684	COG5002	protein histidine kinase activity
YPTS_3684	COG0784	Response regulator, receiver
YPTS_3686	COG1242	4 iron, 4 sulfur cluster binding
YPTS_3687	COG0070	glutamate synthase
YPTS_3687	COG0069	glutamate synthase activity
YPTS_3687	COG0067	glutamate synthase
YPTS_3688	COG0493	'glutamate synthase
YPTS_3690	COG2969	positive regulation of protein catabolic process
YPTS_3691	COG0625	glutathione transferase activity
YPTS_3694	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YPTS_3696	COG3105	Protein conserved in bacteria
YPTS_3697	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPTS_3698	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPTS_3700	COG5007	Belongs to the BolA IbaG family
YPTS_3701	COG3113	response to antibiotic
YPTS_3702	COG2854	intermembrane phospholipid transfer
YPTS_3703	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPTS_3704	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPTS_3705	COG1127	ABC transporter
YPTS_3706	COG0530	calcium, potassium:sodium antiporter activity
YPTS_3707	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPTS_3707	COG0517	IMP dehydrogenase activity
YPTS_3708	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPTS_3709	COG3117	lipopolysaccharide transmembrane transporter activity
YPTS_3710	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPTS_3711	COG1137	ATPase activity
YPTS_3712	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPTS_3714	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_3716	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_3721	COG1609	Transcriptional regulator
YPTS_3722	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPTS_3722	COG1263	PTS System
YPTS_3723	COG0366	Alpha amylase catalytic
YPTS_3724	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPTS_3725	COG3783	Cytochrome b(562)
YPTS_3727	COG0312	modulator of DNA gyrase
YPTS_3729	COG2732	(Barnase) inhibitor
YPTS_3735	COG0583	DNA-binding transcription factor activity
YPTS_3745	COG0312	modulator of DNA gyrase
YPTS_3746	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPTS_3747	COG3164	Protein of unknown function
YPTS_3748	COG1530	ribonuclease E activity
YPTS_3750	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPTS_3751	COG1792	Involved in formation and maintenance of cell shape
YPTS_3752	COG1077	Cell shape determining protein MreB Mrl
YPTS_3753	COG2199	diguanylate cyclase activity
YPTS_3753	COG2200	EAL domain
YPTS_3754	COG0604	alcohol dehydrogenase
YPTS_3758	COG0511	ligase activity, forming carbon-carbon bonds
YPTS_3759	COG0439	Biotin carboxylase
YPTS_3761	COG3924	membrane
YPTS_3762	COG4145	pantothenate transmembrane transporter activity
YPTS_3764	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPTS_3765	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YPTS_3769	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPTS_3771	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPTS_3772	COG3133	Outer membrane lipoprotein
YPTS_3774	COG1278	Cold shock
YPTS_3775	COG1278	Cold shock
YPTS_3776	COG1278	Cold shock
YPTS_3780	COG0625	glutathione transferase activity
YPTS_3782	COG1069	ribulokinase activity
YPTS_3784	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_3785	COG1129	ABC transporter
YPTS_3787	COG1560	Kdo2-lipid A biosynthetic process
YPTS_3789	COG0025	NhaP-type Na H and K H
YPTS_3790	COG2252	PERMEase
YPTS_3791	COG3077	Addiction module antitoxin, RelB DinJ family
YPTS_3793	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPTS_3795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPTS_3796	COG0431	NADPH-dependent FMN reductase
YPTS_3798	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_3799	COG1869	D-ribose catabolic process
YPTS_3800	COG2207	Transcriptional regulator
YPTS_3801	COG0673	inositol 2-dehydrogenase activity
YPTS_3803	COG3501	Rhs element vgr protein
YPTS_3805	COG3209	COG3209 Rhs family protein
YPTS_3807	COG3501	Rhs element vgr protein
YPTS_3831	COG1175	transmembrane transport
YPTS_3832	COG3833	ABC-type maltose transport systems, permease component
YPTS_3836	COG0527	aspartate kinase activity
YPTS_3840	COG1414	Transcriptional regulator
YPTS_3842	COG2224	Isocitrate lyase
YPTS_3843	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPTS_3851	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPTS_3854	COG0551	DNA topoisomerase type I activity
YPTS_3856	COG0758	DNA mediated transformation
YPTS_3860	COG0569	domain protein
YPTS_3862	COG3036	rescue of stalled ribosome
YPTS_3863	COG0789	Transcriptional regulator
YPTS_3866	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPTS_3869	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPTS_3870	COG0201	protein transport
YPTS_3872	COG1841	ribosomal large subunit assembly
YPTS_3880	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPTS_3881	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YPTS_3883	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YPTS_3884	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YPTS_3886	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YPTS_3891	COG0051	transcription antitermination factor activity, RNA binding
YPTS_3896	COG0049	tRNA binding
YPTS_3897	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YPTS_3901	COG2964	Protein conserved in bacteria
YPTS_3902	COG0545	Peptidyl-prolyl cis-trans isomerase
YPTS_3904	COG1047	Peptidyl-prolyl cis-trans
YPTS_3905	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YPTS_3908	COG0488	(ABC) transporter
YPTS_3909	COG1216	Glycosyl transferase, family 2
YPTS_3911	COG2175	clavaminate synthase activity
YPTS_3912	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPTS_3914	COG4521	taurine ABC transporter
YPTS_3916	COG0429	hydrolase of the alpha beta-hydrolase fold
YPTS_3918	COG3954	Phosphoribulokinase
YPTS_3920	COG1765	OsmC-like protein
YPTS_3922	COG1289	transmembrane transporter activity
YPTS_3926	COG0433	COG0433 Predicted ATPase
YPTS_3927	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPTS_3929	COG1486	melibiose metabolic process
YPTS_3933	COG0402	S-adenosylhomocysteine deaminase activity
YPTS_3935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPTS_3936	COG2146	nitrite reductase [NAD(P)H] activity
YPTS_3939	COG0180	Tryptophanyl-tRNA synthetase
YPTS_3941	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPTS_3946	COG4796	Type ii and iii secretion system protein
YPTS_3951	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YPTS_3952	COG0494	nUDIX hydrolase
YPTS_3955	COG1011	Hydrolase
YPTS_3956	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPTS_3960	COG0745	RESPONSE REGULATOR receiver
YPTS_3961	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPTS_3962	COG2183	response to ionizing radiation
YPTS_3963	COG1918	ferrous iron import across plasma membrane
YPTS_3970	COG1640	4-alpha-glucanotransferase
YPTS_3971	COG0058	SHG alpha-glucan phosphorylase activity
YPTS_3975	COG1349	DNA-binding transcription factor activity
YPTS_3979	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPTS_3980	COG0058	SHG alpha-glucan phosphorylase activity
YPTS_3985	COG3275	phosphorelay sensor kinase activity
YPTS_3990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPTS_3991	COG2095	MarC family integral membrane protein
YPTS_3994	COG3157	Type VI secretion system effector, Hcp
YPTS_3995	COG3265	gluconokinase activity
YPTS_3996	COG2610	gluconate transmembrane transporter activity
YPTS_3997	COG1609	Transcriptional regulator
YPTS_3998	COG1741	Belongs to the pirin family
YPTS_4000	COG0745	RESPONSE REGULATOR receiver
YPTS_4002	COG0191	fructose-bisphosphate aldolase activity
YPTS_4004	COG1879	ABC-type sugar transport system periplasmic component
YPTS_4005	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPTS_4023	COG2081	HI0933 family
YPTS_4024	COG0306	phosphate transporter
YPTS_4026	COG0589	response to stress
YPTS_4030	COG0339	signal peptide processing
YPTS_4031	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPTS_4032	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPTS_4033	COG3835	regulator
YPTS_4034	COG2610	gluconate transmembrane transporter activity
YPTS_4035	COG1929	Belongs to the glycerate kinase type-1 family
YPTS_4040	COG1295	ribonuclease BN
YPTS_4041	COG2134	cdp-diacylglycerol pyrophosphatase
YPTS_4042	COG2982	Protein involved in outer membrane biogenesis
YPTS_4043	COG2200	EAL domain
YPTS_4044	COG1942	4-Oxalocrotonate Tautomerase
YPTS_4045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_4046	COG0612	Peptidase, M16
YPTS_4051	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPTS_4052	COG2200	EAL domain
YPTS_4052	COG2199	diguanylate cyclase activity
YPTS_4053	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
YPTS_4054	COG4608	Belongs to the ABC transporter superfamily
YPTS_4055	COG0444	Belongs to the ABC transporter superfamily
YPTS_4056	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPTS_4057	COG0601	transmembrane transport
YPTS_4058	COG0747	negative chemotaxis
YPTS_4060	COG2831	hemolysin activation secretion protein
YPTS_4063	COG2271	Major facilitator Superfamily
YPTS_4064	COG3851	Histidine kinase
YPTS_4065	COG2197	response regulator
YPTS_4066	COG2194	sulfuric ester hydrolase activity
YPTS_4072	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YPTS_4075	COG4607	ABC-type enterochelin transport system periplasmic component
YPTS_4077	COG4605	iron ion homeostasis
YPTS_4078	COG4604	ABC transporter, ATP-binding protein
YPTS_4086	COG2003	Belongs to the UPF0758 family
YPTS_4095	COG1715	Restriction endonuclease
YPTS_4097	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
YPTS_4103	COG0582	viral genome integration into host DNA
YPTS_4104	COG2207	Transcriptional regulator
YPTS_4104	COG1609	Transcriptional regulator
YPTS_4105	COG4214	carbohydrate transport
YPTS_4107	COG4213	ABC transporter substrate-binding protein
YPTS_4109	COG1070	Carbohydrate kinase
YPTS_4111	COG3121	Chaperone
YPTS_4112	COG3188	usher protein
YPTS_4114	COG3274	enterobacterial common antigen metabolic process
YPTS_4116	COG2801	Transposase and inactivated derivatives
YPTS_4117	COG2423	ornithine cyclodeaminase activity
YPTS_4118	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPTS_4119	COG0823	Involved in the tonB-independent uptake of proteins
YPTS_4120	COG5645	(Lipo)protein
YPTS_4124	COG3977	Valine--pyruvate aminotransferase
YPTS_4126	COG0366	Alpha amylase catalytic
YPTS_4129	COG2885	chlorophyll binding
YPTS_4132	COG2818	Glycosylase
YPTS_4138	COG2213	PTS system mannitol-specific
YPTS_4138	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPTS_4140	COG3722	fumarate hydratase activity
YPTS_4147	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPTS_4149	COG0243	molybdopterin cofactor binding
YPTS_4149	COG3383	formate dehydrogenase (NAD+) activity
YPTS_4150	COG3383	formate dehydrogenase (NAD+) activity
YPTS_4150	COG0243	molybdopterin cofactor binding
YPTS_4151	COG0437	4 iron, 4 sulfur cluster binding
YPTS_4152	COG2864	formate dehydrogenase
YPTS_4155	COG3276	selenocysteine insertion sequence binding
YPTS_4160	COG2186	Transcriptional regulator
YPTS_4161	COG0477	Major facilitator Superfamily
YPTS_4163	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPTS_4169	COG1522	sequence-specific DNA binding
YPTS_4170	COG0716	FMN binding
YPTS_4173	COG3312	ion transport
YPTS_4184	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YPTS_4186	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPTS_4187	COG0573	inorganic phosphate transmembrane transporter activity
YPTS_4188	COG0581	inorganic phosphate transmembrane transporter activity
YPTS_4190	COG0704	Plays a role in the regulation of phosphate uptake
YPTS_4192	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPTS_4193	COG0765	amino acid transport
YPTS_4194	COG0765	amino acid transport
YPTS_4195	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPTS_4196	COG2252	PERMEase
YPTS_4202	COG0706	membrane insertase activity
YPTS_4205	COG0230	Belongs to the bacterial ribosomal protein bL34 family
YPTS_4215	COG4669	(LipO)protein
YPTS_4217	COG1317	bacterial-type flagellum organization
YPTS_4218	COG5599	Phosphatase
YPTS_4219	COG2963	transposase activity
YPTS_4222	COG2801	Transposase and inactivated derivatives
YPTS_4239	COG2801	Transposase and inactivated derivatives
YPTS_4245	COG2801	Transposase and inactivated derivatives
YPTS_4250	COG2801	Transposase and inactivated derivatives
YPTS_4252	COG5599	Phosphatase
YPTS_4254	COG3609	addiction module antidote protein, CC2985 family
YPTS_4257	COG1475	DNA binding
YPTS_4258	COG1192	Involved in chromosome partitioning
YPTS_4261	COG2801	Transposase and inactivated derivatives
YPTS_4270	COG4886	Leucine-rich repeat (LRR) protein
YPTS_4270	COG4886	Leucine-rich repeat (LRR) protein
YPTS_4272	COG3328	transposase activity
YPTS_4279	COG4789	Type iii secretion
YPTS_4288	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YPTS_4289	COG4790	Type iii secretion
YPTS_4290	COG4794	Type iii secretion
YPTS_4291	COG4791	protein targeting
YPTS_4292	COG4792	protein secretion