locus-tag class description BZ16_10 ENOG4105CQ2 DNA polymerase BZ16_1000 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BZ16_101 ENOG4105C0H protease BZ16_1010 ENOG4107ZSV Receptor BZ16_1011 ENOG4108IQC 2,3-dihydroxybenzoate-AMP ligase BZ16_1015 ENOG4105C0W non-ribosomal peptide synthetase BZ16_1018 ENOG4105BZ1 (ABC) transporter BZ16_1019 ENOG4105EYM Major Facilitator superfamily BZ16_102 ENOG4105BZU Histidine kinase BZ16_1024 ENOG4108KX4 response regulator BZ16_1025 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BZ16_1027 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BZ16_1028 ENOG4108TSE Transferase BZ16_103 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ16_1032 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BZ16_1038 ENOG4105BZ1 (ABC) transporter BZ16_104 ENOG4105DXN mazG family BZ16_1042 ENOG4105N4N Protein of unknown function (DUF2766) BZ16_1043 ENOG4105TIK BZ16_1044 ENOG41064PC BZ16_1047 ENOG4105C85 amino acid BZ16_1050 ENOG4105VEQ Cold shock protein BZ16_1051 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ16_1052 ENOG4105DHI Methyltransferase BZ16_1054 ENOG4105BZU Histidine kinase BZ16_1058 ENOG4105F3R pts system mannose fructose sorbose family iid BZ16_1059 ENOG4105ETZ PTS System BZ16_1060 ENOG4108EQA pts system BZ16_1061 ENOG4105EE5 Membrane protein terC BZ16_1062 ENOG4108V8F Transcriptional regulator, MarR family BZ16_1065 ENOG4105C26 Dehydrogenase BZ16_1066 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase BZ16_1071 ENOG4105EFA 4-hydroxyphenylacetate BZ16_1072 ENOG4107UWN reductase BZ16_1073 ENOG4105EJQ L-serine dehydratase BZ16_1075 ENOG4105CRQ synthase (Component I) BZ16_1078 ENOG4105C1J atp-dependent rna helicase BZ16_1079 ENOG4105X2V dna damage-inducible protein BZ16_108 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BZ16_1082 ENOG4105CUG Oligopeptidase b BZ16_1084 ENOG4105MPK DNA polymerase III subunit theta BZ16_1085 ENOG41090A1 ferritin BZ16_1086 ENOG4105FXM Copper resistance protein BZ16_1088 ENOG4105NKT exported protein BZ16_109 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BZ16_1093 ENOG4105D00 flagellar biosynthetic protein flhB BZ16_1094 ENOG4105D7B Flagellar biosynthesis protein flha BZ16_1095 ENOG4105W13 flagellar protein BZ16_1097 ENOG4105QVD Flagella synthesis protein FlgN BZ16_1098 ENOG4105M9M anti-sigma28 factor FlgM BZ16_1099 ENOG4105CKS Flagella basal body P-ring formation protein flgA BZ16_11 ENOG4108KF1 Membrane BZ16_1100 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ16_1101 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ16_1102 ENOG4105W00 Flagellar hook capping protein BZ16_1103 ENOG4105BZE flagellar hook protein, FlgE BZ16_1104 ENOG4108KPB Flagellar basal-body rod protein FlgF BZ16_1105 ENOG4105CGA flagellar basal-body rod protein FlgG BZ16_1108 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BZ16_1109 ENOG4105E1Q flagellar hook-associated protein BZ16_1110 ENOG4105DTJ flagellar hook-associated protein BZ16_1111 ENOG4105DKT Transcriptional regulator BZ16_1114 ENOG4105CNN ABC, transporter BZ16_1116 ENOG4105C2J ABC transporter BZ16_1117 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BZ16_1118 ENOG4108MGF sugar kinase BZ16_1121 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ16_1122 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ16_1123 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ16_1125 ENOG4105DD5 Flagellar motor switch protein BZ16_1126 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ16_1127 ENOG4107ZI8 flagellar basal body-associated protein flil BZ16_1128 ENOG4105WF4 Flagellar hook-length control protein BZ16_1129 ENOG4105GSA Flagellar export protein flij BZ16_1130 ENOG4108JIR Flagellum-specific ATP synthase BZ16_1131 ENOG41090PJ Flagellar assembly protein BZ16_1132 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ16_1133 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ16_1134 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BZ16_1138 ENOG4105DHT Metal Dependent Phosphohydrolase BZ16_1141 ENOG4105MQ3 flagellar protein FliS BZ16_1142 ENOG4105DTS flagellar hook-associated BZ16_1143 ENOG4105I03 Flagellin BZ16_1144 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ16_1145 ENOG4108M9K flagella biosynthesis protein FliZ BZ16_1147 ENOG4105EAB amino acid AbC transporter BZ16_1148 ENOG4105E5Q amino acid AbC transporter BZ16_1149 ENOG4105CDA abc transporter atp-binding protein BZ16_1152 ENOG4105C26 Dehydrogenase BZ16_1154 ENOG4105CK7 Sodium proline symporter BZ16_1160 ENOG4105C85 amino acid BZ16_1162 ENOG4108T1M outer membrane protein x BZ16_1164 ENOG4105RA2 Membrane BZ16_1165 ENOG4105XVG cytoplasmic protein BZ16_1166 ENOG4105WH1 Two component transcriptional regulator luxr family BZ16_1172 ENOG4105ZTC transcriptional activator, Ogr delta BZ16_118 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BZ16_1185 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ16_119 ENOG4105N0Z inner membrane protein ygbE BZ16_1199 ENOG4105ED4 portal protein BZ16_1204 ENOG4105VZ1 Replication Protein BZ16_1206 ENOG4105DFE Dna adenine methylase BZ16_1207 ENOG4108IRC dna polymerase iii BZ16_1221 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ16_1228 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ16_1258 ENOG4105FDP GntR family transcriptional regulator BZ16_1259 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BZ16_126 ENOG4108K5P (LipO)protein BZ16_1262 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BZ16_1263 ENOG4108IJ9 (ABC) transporter BZ16_1265 ENOG4108MQF Chaperone BZ16_1267 ENOG4105CW0 outer membrane usher protein BZ16_127 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ16_1270 ENOG4105BZU Histidine kinase BZ16_1271 ENOG4108Q9V regulatoR BZ16_1272 ENOG4105CYC Transferase BZ16_1273 ENOG4105DJG MaoC domain protein dehydratase BZ16_1278 ENOG4107RGD Major Facilitator superfamily BZ16_1281 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ16_1282 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BZ16_1283 ENOG4105C85 amino acid BZ16_1284 ENOG4105MVE transcriptional regulator BZ16_1285 ENOG4105CSV Glutaminase BZ16_1287 ENOG4107SJW iron permease, FTR1 BZ16_129 ENOG4108YZG isomerase BZ16_1290 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BZ16_1292 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BZ16_1296 ENOG4105H1N peptidase, M24 BZ16_1297 ENOG4108TUY outer membrane protein PgaA BZ16_1298 ENOG4107BJW polysaccharide deacetylase BZ16_1299 ENOG4105CND Glycosyl transferase, family 2 BZ16_13 ENOG4106SMU thiamine transporter membrane protein BZ16_130 ENOG4105CPQ Dehydrogenase BZ16_1300 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD BZ16_1303 ENOG4105D5M phosphate starvation-inducible protein BZ16_1304 ENOG4105EWV Sodium calcium exchanger membrane region BZ16_1305 ENOG4105BZU Histidine kinase BZ16_1306 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BZ16_131 ENOG4105CHR reductase BZ16_1317 ENOG4105FCK Membrane BZ16_132 ENOG4105CMT Dihydroxyacetone kinase BZ16_1320 ENOG4105CZE histidine utilization repressor BZ16_1321 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BZ16_1324 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BZ16_1325 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ16_1338 ENOG4108WF3 methyltransferase BZ16_134 ENOG4105DKT Transcriptional regulator BZ16_1347 ENOG4105GR3 Histidine kinase BZ16_1349 ENOG4105ENX hydrolase BZ16_1353 ENOG4105C3G gtp-binding protein BZ16_1355 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria BZ16_1356 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BZ16_1361 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BZ16_1362 ENOG4108YY7 Invasion gene expression up-regulator SirB BZ16_1363 ENOG41063JG Transcriptional regulator BZ16_1365 ENOG4105CHH sulfate transporter BZ16_1369 ENOG4105EG2 ABC transporter, permease BZ16_1370 ENOG4105F38 ABC transporter, permease BZ16_1372 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BZ16_1373 ENOG4105E2R ROK family BZ16_1376 ENOG4107XHZ cytoplasmic chaperone TorD family protein BZ16_1377 ENOG4105F3T (LipO)protein BZ16_1379 ENOG4105D9U N-acetyltransferase BZ16_1382 ENOG4105CJR Integral membrane protein (MviN BZ16_1387 ENOG4106ZCM YecM protein BZ16_139 ENOG4105E89 ABC transporter BZ16_1391 ENOG4105WJG Glutathione BZ16_1392 ENOG41081XQ Conserved Protein BZ16_1394 ENOG4108TIT dATP pyrophosphohydrolase BZ16_1399 ENOG4105FAV ABC, transporter BZ16_14 ENOG4105DP9 ABC transporter BZ16_140 ENOG4105CA0 peroxidase BZ16_1401 ENOG4105NXV High-affinity zinc uptake system protein BZ16_1402 ENOG4105DR5 peptidase BZ16_1403 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BZ16_1404 ENOG4105CA9 Pyruvate kinase BZ16_1405 ENOG4106KNT transcriptional regulator BZ16_1406 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BZ16_1408 ENOG4108UHU Aldolase BZ16_1411 ENOG4105M4H endoribonuclease L-psp BZ16_1412 ENOG4105DVT helicase BZ16_1413 ENOG41072GX Peptidase M22 Glycoprotease BZ16_1414 ENOG4105Y4Z Outer Membrane Lipoprotein BZ16_1415 ENOG4105CEY Amp-dependent synthetase and ligase BZ16_1416 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BZ16_1417 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) BZ16_1418 ENOG4107QMS site-determining protein BZ16_1421 ENOG4105CVE Lytic murein transglycosylase BZ16_1422 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BZ16_1425 ENOG4105C3J Cysteine desulfurase BZ16_143 ENOG4105D05 Receptor BZ16_1431 ENOG4105ED1 spovr family BZ16_1433 ENOG4105CNH Multidrug resistance protein MdtL BZ16_1434 ENOG4105EUB pirin domain protein BZ16_1435 ENOG4105HEI LysR family (Transcriptional regulator BZ16_1438 ENOG4105CYN Serine protein kinase BZ16_1439 ENOG4105GNX MltA-interacting MipA family protein BZ16_1440 ENOG4105DSB aldose 1-epimerase BZ16_1443 ENOG4105VUT cytoplasmic protein BZ16_1444 ENOG4108RWI nicotinamidase BZ16_1445 ENOG4105HDK L-asparaginase BZ16_1446 ENOG4105D07 Signal peptide peptidase, SppA BZ16_1447 ENOG41069NU Nitroreductase BZ16_1449 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ16_145 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ16_1450 ENOG4105MTM Protein of unknown function (DUF1496) BZ16_1451 ENOG4105M6F mutator MutT protein BZ16_1452 ENOG4105CGK Exodeoxyribonuclease III BZ16_1453 ENOG4105SKE transcriptional Regulator LysR family BZ16_1456 ENOG4105CIY formyltetrahydrofolate deformylase BZ16_1458 ENOG4105I93 response regulator BZ16_1459 ENOG4105C6Y Udp-glucose 6-dehydrogenase BZ16_1461 ENOG4107104 thymidine kinase BZ16_1462 ENOG4108EKI Dehydrogenase BZ16_1463 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BZ16_1464 ENOG4107QSI ABC, transporter BZ16_1466 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ16_1467 ENOG4105C3U ABC transporter BZ16_1468 ENOG4108JQ7 (ABC) transporter BZ16_147 ENOG4107GFK fumarate BZ16_1472 ENOG4108T1M outer membrane protein x BZ16_1475 ENOG4105K9H YciI-like protein BZ16_1477 ENOG410822N TonB family BZ16_1478 ENOG4105NAU thioesterase Superfamily protein BZ16_148 ENOG4105CMG Carbohydrate kinase BZ16_1482 ENOG4105EIF outer membrane protein W BZ16_1486 ENOG4105DK0 Indole-3-glycerol phosphate synthase BZ16_1488 ENOG4105DDQ anthranilate synthase BZ16_149 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase BZ16_1490 ENOG4105DB7 PHP domain protein BZ16_1491 ENOG4107RTD sua5 ycio yrdc ywlc family protein BZ16_1492 ENOG4105FE9 pseudouridine synthase BZ16_1493 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BZ16_1494 ENOG4105UBK short-chain dehydrogenase reductase BZ16_1495 ENOG4105ERU peptidase BZ16_1496 ENOG4105RKX Protein of unknown function (DUF2498) BZ16_1498 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ16_1499 ENOG4107R11 Transcriptional regulator BZ16_150 ENOG4105F5R ABC transporter BZ16_1501 ENOG4107QM5 aconitate hydratase BZ16_1502 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BZ16_1503 ENOG4105EYK Phosphatidylglycerophosphatase B BZ16_1504 ENOG4105Q4A inner membrane protein yciS BZ16_1505 ENOG4105CFV Tetratricopeptide repeat protein BZ16_1508 ENOG4108ZJT translation initiation factor, Sui1 BZ16_1509 ENOG41061RM osmotically inducible lipoprotein BZ16_151 ENOG4105CNN ABC, transporter BZ16_1510 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ16_1512 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BZ16_1513 ENOG4105VCD cytoplasmic protein BZ16_1514 ENOG4105D22 carbon starvation protein BZ16_1516 ENOG4105CSP Major Facilitator Superfamily BZ16_1517 ENOG4105EXW epimerase dehydratase BZ16_1518 ENOG4105CSM endonuclease III BZ16_152 ENOG4105C2J ABC transporter BZ16_1520 ENOG4108UQQ Electron transport complex BZ16_1522 ENOG4105UEI Transcriptional Regulator AraC Family BZ16_1526 ENOG4105M9B inner membrane protein ydgK BZ16_1529 ENOG4108JJA ABC, transporter BZ16_1533 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator BZ16_1535 ENOG4105CNN ABC, transporter BZ16_1537 ENOG4105D9R oxidoreductase BZ16_1538 ENOG4105DHU Bile acid BZ16_154 ENOG4105E98 transcriptional regulator DeoR family BZ16_1542 ENOG4105CI1 PTS System BZ16_1543 ENOG4105FDP GntR family transcriptional regulator BZ16_1544 ENOG4106J39 exported protein BZ16_1545 ENOG4105EIP mannose-6-phosphate isomerase BZ16_1546 ENOG4105C9Q fumarate hydratase class II BZ16_1548 ENOG4105D94 Major Facilitator Superfamily BZ16_1549 ENOG4106NZI LysR family Transcriptional regulator BZ16_155 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ16_1550 ENOG4105DAG ROK family BZ16_1552 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ16_1554 ENOG4105KBG Protein of unknown function (DUF1161) BZ16_1556 ENOG4105EMU Dehydrogenase BZ16_1557 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BZ16_1559 ENOG4105EMU Dehydrogenase BZ16_156 ENOG4107QY8 reductase BZ16_1560 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BZ16_1561 ENOG4105C26 Dehydrogenase BZ16_1563 ENOG4105DWP Membrane BZ16_1564 ENOG4105C87 Aminotransferase class I and II BZ16_1565 ENOG4105DFD Na H antiporter BZ16_1566 ENOG41060NJ transcriptional regulator BZ16_1568 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ16_1569 ENOG4105CNN ABC, transporter BZ16_157 ENOG4105QAX Iron-sulfur BZ16_1570 ENOG4105C2J ABC transporter BZ16_1572 ENOG4107UWC ABC, transporter BZ16_1573 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ16_1575 ENOG4105FYV Amp nucleosidase BZ16_158 ENOG4107KGK dmso reductase anchor subunit BZ16_1580 ENOG4105C7K acetolactate synthase BZ16_1581 ENOG4105M71 acetolactate synthase 1 regulatory subunit BZ16_1582 ENOG4105PAD Hydrolase BZ16_1585 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ16_1586 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BZ16_1587 ENOG4105Q9Y Universal stress protein BZ16_1588 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ16_1589 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ16_159 ENOG4108NEM leader-binding protein dmsD BZ16_1590 ENOG4105C5D exported protein BZ16_1591 ENOG4105D5Q Arginine ornithine antiporter BZ16_1593 ENOG4107EXC regulatoR BZ16_1594 ENOG4105JJR Histidine kinase BZ16_1595 ENOG4105CTD carboxy-peptidase BZ16_1598 ENOG4105DS1 cytochrome b561 BZ16_160 ENOG4105CPW cytochrome b561 BZ16_1600 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap BZ16_1603 ENOG4105CQ7 ATP-dependent helicase BZ16_1605 ENOG4105DKT Transcriptional regulator BZ16_1606 ENOG4105DEI Mannitol dehydrogenase BZ16_1607 ENOG4105WXT Conserved Protein BZ16_1608 ENOG410689M (LipO)protein BZ16_1609 ENOG4107H52 Dicarboxylate transport BZ16_161 ENOG4108XVM Cytochrome b(562) BZ16_1610 ENOG4105C5I Dehydrogenase BZ16_1611 ENOG41090X5 Heat shock protein hslJ BZ16_1613 ENOG4105KT7 mgtC SapB transporter BZ16_1615 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) BZ16_1621 ENOG4107QSI ABC, transporter BZ16_1622 ENOG4105KXI murein peptide amidase A BZ16_1623 ENOG4107S8C mandelate racemase muconate lactonizing BZ16_1624 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BZ16_1629 ENOG4105CM6 amino acid regulated cytosolic protein BZ16_1631 ENOG4105FM1 phage shock protein C BZ16_1632 ENOG4105YYT phage shock protein B BZ16_1633 ENOG41087YS Phage shock protein A BZ16_1634 ENOG4105E51 psp operon transcriptional activator BZ16_1635 ENOG4108HIY periplasmic BZ16_1636 ENOG4108I5W peptide transport system, permease protein BZ16_1637 ENOG4108EU3 peptide transport system, permease BZ16_1638 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein BZ16_1639 ENOG4108JQ2 peptide transport system atp-binding protein BZ16_1640 ENOG4105Q4T oxidoreductase BZ16_1642 ENOG4105DUX Transporter BZ16_1643 ENOG41069YE inner membrane protein yohC BZ16_1644 ENOG4108ZR5 Conserved Protein BZ16_1645 ENOG4108K3A Glutathione S-transferase BZ16_1649 ENOG4107RGM aldo keto reductase BZ16_165 ENOG4105C2J ABC transporter BZ16_1650 ENOG4105XZD Fe-S protein BZ16_1651 ENOG4105DIJ Phosphoethanolamine transferase BZ16_1652 ENOG4108WUH Transcriptional regulator, TetR family BZ16_1653 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ16_1655 ENOG4108UYE Lactoylglutathione lyase BZ16_1657 ENOG4105M2J Glutaredoxin BZ16_1659 ENOG4105K4H Nlp p60 protein BZ16_166 ENOG4105CNN ABC, transporter BZ16_1660 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ16_1663 ENOG4105F52 Transcriptional regulator BZ16_1664 ENOG4105CZQ inner membrane transport protein YdhC BZ16_1665 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BZ16_1666 ENOG4108R6K riboflavin synthase, subunit alpha BZ16_167 ENOG4108HHA Transketolase BZ16_1671 ENOG4105CA9 Pyruvate kinase BZ16_1672 ENOG4105KMX major outer membrane lipoprotein BZ16_1673 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BZ16_1676 ENOG4105JRK feS assembly protein SufD BZ16_1677 ENOG4105C3K feS assembly ATPase SufC BZ16_1678 ENOG4105DIW FeS assembly protein SUFB BZ16_1679 ENOG4108Z4V iron-sulfur cluster assembly BZ16_168 ENOG4108IUS Transketolase BZ16_1680 ENOG4105KA0 thioesterase Superfamily protein BZ16_1681 ENOG4105CQB FAD linked oxidase domain protein BZ16_1682 ENOG4105IPI Membrane BZ16_1683 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BZ16_1685 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ16_1688 ENOG4108QBX (LipO)protein BZ16_169 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BZ16_1696 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) BZ16_1697 ENOG4108V06 Glutathione peroxidase BZ16_17 ENOG4105CMM transposase BZ16_1700 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BZ16_1707 ENOG41087WU BZ16_1711 ENOG4105DSE periplasmic solute binding protein BZ16_1712 ENOG4105DIK (ABC) transporter BZ16_1713 ENOG4105CC5 ABC transporter BZ16_1714 ENOG4105CC5 ABC transporter BZ16_1715 ENOG4105FGM Fructosamine kinase BZ16_1716 ENOG4107PN8 YfeABCD locus regulator BZ16_1717 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 BZ16_1718 ENOG4105M5J Cupin 2, conserved barrel domain protein BZ16_1720 ENOG4105CHR reductase BZ16_1721 ENOG41061NF Pectate lyase BZ16_1722 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BZ16_1723 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BZ16_1725 ENOG4105WEM extracellular solute-binding protein BZ16_1726 ENOG4108PU9 oligogalacturonate-specific porin BZ16_1727 ENOG4107K5X Membrane-bound metal-dependent hydrolase BZ16_1728 ENOG4108ETY sodium dicarboxylate symporter BZ16_1729 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ16_1731 ENOG4105CAZ oligogalacturonide lyase BZ16_1732 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ16_1733 ENOG4108VEV chaperone BZ16_1736 ENOG4108VEV chaperone BZ16_1737 ENOG4105H8W Fimbrial protein BZ16_1740 ENOG4105CN1 protease BZ16_1742 ENOG4108ZGC gaf domain protein BZ16_1743 ENOG4105H2K paraquat-inducible protein a BZ16_1744 ENOG4105DY2 Paraquat-inducible protein b BZ16_1748 ENOG4105GQR Chaperone BZ16_1751 ENOG4105WT8 Protein of unknown function (DUF1480) BZ16_1758 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ16_1762 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ16_1763 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) BZ16_1764 ENOG4108VYJ response regulator receiver protein BZ16_1766 ENOG4105BZU Histidine kinase BZ16_1767 ENOG4105C8Q Methyl-accepting chemotaxis BZ16_1768 ENOG4105C8Q Methyl-accepting chemotaxis BZ16_177 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BZ16_1771 ENOG4108V3W Chemotaxis protein, CheW BZ16_1772 ENOG4105CBS Chea signal transduction histidine kinase BZ16_1773 ENOG4105ER2 Ompa motb domain protein BZ16_1774 ENOG4107RD7 Flagellar Motor Protein, MotA BZ16_1775 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region BZ16_1777 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BZ16_1778 ENOG4105KT7 mgtC SapB transporter BZ16_1779 ENOG4105C8Q Methyl-accepting chemotaxis BZ16_1781 ENOG4105VEQ Cold shock protein BZ16_1785 ENOG4105GSJ Inner membrane protein ylaC BZ16_1786 ENOG4108XM1 transcriptional regulator AsnC family BZ16_1788 ENOG41061EV selenium-binding protein YdfZ BZ16_1789 ENOG4105D6F Phosphatase BZ16_1791 ENOG4105KVH Transcriptional regulator BZ16_1792 ENOG4105ECR NmrA family BZ16_1793 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BZ16_1795 ENOG4106NDP Transcriptional regulator BZ16_1796 ENOG4108HMX isocitrate dehydrogenase (NADP) BZ16_1797 ENOG4108R99 pseudouridine synthase BZ16_1801 ENOG4107QTF adenylosuccinate lyase BZ16_1803 ENOG4105XJC Two component transcriptional regulator (Winged helix family BZ16_1805 ENOG4105EZE Cupin 4 family protein BZ16_1807 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BZ16_1809 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ16_1811 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ16_1812 ENOG4108JA2 transcriptioN-repair coupling factor BZ16_1813 ENOG4107MBR 17 kDa surface antigen BZ16_1816 ENOG4105CEP NADH dehydrogenase BZ16_1821 ENOG41090DQ Lipoprotein BZ16_1822 ENOG4105K59 histidine triad (HIT) protein BZ16_1823 ENOG4105F9E Shikimate 5-dehydrogenase BZ16_183 ENOG4107VXZ Hydrolase BZ16_1830 ENOG4105ED4 portal protein BZ16_1833 ENOG4105CI1 PTS System BZ16_1834 ENOG4105F8V Hydrolase, tatD family BZ16_1835 ENOG4107QRG dna polymerase iii BZ16_1837 ENOG4105HHA aminodeoxychorismate lyase BZ16_1838 ENOG4105YAZ 4-amino-4-deoxychorismate lyase BZ16_1839 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ16_184 ENOG4105W39 Membrane BZ16_1841 ENOG4105CHR reductase BZ16_1842 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ16_1845 ENOG4105VGS 50s ribosomal protein l32 BZ16_1846 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BZ16_1848 ENOG4105EI2 Pseudouridine synthase BZ16_1850 ENOG4107QQB Ribonuclease E BZ16_1851 ENOG41067V3 Antibiotic biosynthesis monooxygenase BZ16_1854 ENOG4105PVA Biofilm formation regulatory protein BssS BZ16_1858 ENOG4105DSF transport protein BZ16_1861 ENOG4105D1S lipid A biosynthesis BZ16_1862 ENOG4105DUX Transporter BZ16_1863 ENOG4105NAC (LipO)protein BZ16_1864 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) BZ16_1865 ENOG4105DJ9 glucan biosynthesis protein BZ16_1866 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) BZ16_187 ENOG4108JU6 CBS domain protein BZ16_1870 ENOG4105VJY transcriptional regulator BZ16_1871 ENOG4107YC3 synthase BZ16_1872 ENOG4105ETT transcriptional Regulator, LysR family BZ16_1874 ENOG4105C54 Major Facilitator superfamily BZ16_1876 ENOG4105CPC Aldo Keto reductase BZ16_1877 ENOG4108Y1S CRISPR-associated protein, Csy4 family BZ16_1878 ENOG4105M6W Crispr-associated protein, Csy3 family BZ16_1879 ENOG4105DZX CRISPR-associated protein, Csy2 family BZ16_188 ENOG4106KVJ cytochrome C assembly protein BZ16_1880 ENOG4105ENG CRISPR-associated protein, Csy1 family BZ16_1881 ENOG4107IIZ CRISPR-associated helicase, Cas3 BZ16_1882 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) BZ16_1883 ENOG4105CUY Mechanosensitive ion channel BZ16_1887 ENOG4105HY2 Glycosidase related protein BZ16_1888 ENOG4105DRS transport system, permease BZ16_189 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BZ16_1891 ENOG4105ETE Transcriptional regulator (LacI family BZ16_1893 ENOG4108IJ9 (ABC) transporter BZ16_1896 ENOG4105CKT filamentous hemagglutinin BZ16_1899 ENOG4105CKT filamentous hemagglutinin BZ16_19 ENOG4105S8Q sugar efflux transporter BZ16_1900 ENOG4105D5K Hemolysin activator protein BZ16_1901 ENOG4105E3J oxidoreductase BZ16_1902 ENOG4105DVW rieske (2Fe-2S) BZ16_1903 ENOG4105C94 Transporter BZ16_1904 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BZ16_1905 ENOG4105EJC lysr family transcriptional regulator BZ16_1906 ENOG4105FKQ transcriptional regulator BZ16_1907 ENOG4105CNN ABC, transporter BZ16_1908 ENOG4105C2J ABC transporter BZ16_1909 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ16_1910 ENOG4105CPQ Dehydrogenase BZ16_1914 ENOG4108T1M outer membrane protein x BZ16_1920 ENOG4107R0W ABC transporter BZ16_1921 ENOG4105E5Q amino acid AbC transporter BZ16_1922 ENOG4105CDA abc transporter atp-binding protein BZ16_1923 ENOG4107SDU Methyl-accepting chemotaxis BZ16_1925 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction BZ16_1926 ENOG4108MTB glycosyl transferase family BZ16_1927 ENOG4105CEY Amp-dependent synthetase and ligase BZ16_1929 ENOG4108IPT Naphthoate synthase BZ16_1932 ENOG4105E4F Isochorismate synthase BZ16_1934 ENOG4105TNS Conserved Protein BZ16_1936 ENOG4105C01 Dihydroxy-acid dehydratase BZ16_1939 ENOG4105C5I Dehydrogenase BZ16_194 ENOG4108NE3 Salt-induced outer membrane protein BZ16_1940 ENOG4105K2J Transcriptional regulator BZ16_1941 ENOG4105F32 YngK protein BZ16_1942 ENOG4105CHR reductase BZ16_1943 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ16_1944 ENOG4108R66 Conserved Protein BZ16_1947 ENOG4105C8S subunit m BZ16_1948 ENOG4105D65 subunit l BZ16_195 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ16_1950 ENOG4107UFS subunit j BZ16_1953 ENOG4108IEH NADH dehydrogenase subunit g BZ16_1954 ENOG4107QIZ NADH dehydrogenase BZ16_1955 ENOG4105GKE subunit e BZ16_1957 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BZ16_1959 ENOG4107NQ8 LysR family Transcriptional regulator BZ16_196 ENOG4108NEV two component transcriptional regulator, LytTR family BZ16_1960 ENOG4105CHM Aminotransferase BZ16_1963 ENOG4107QWE )-transporter BZ16_1964 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 BZ16_1968 ENOG4105C6K Malic enzyme BZ16_1969 ENOG4107P2S Transcriptional regulator BZ16_197 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ16_1972 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BZ16_1973 ENOG4105PTV Nudix Hydrolase BZ16_1974 ENOG4108RE9 Phosphodiesterase BZ16_1976 ENOG4105ECP epimerase BZ16_1977 ENOG4108JEH abc transporter atp-binding protein BZ16_1978 ENOG4106YG3 ABC transporter BZ16_1979 ENOG4105DSP amino acid AbC transporter BZ16_198 ENOG4105EHE chorismate mutase- prephenate dehydrogenase BZ16_1980 ENOG4105E89 ABC transporter BZ16_1981 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BZ16_1982 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BZ16_1983 ENOG4105E96 Colicin v production protein BZ16_1984 ENOG4108S3P Sporulation domain protein BZ16_1985 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BZ16_1987 ENOG4105DQR SNARE associated Golgi BZ16_1989 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ16_1992 ENOG410631K Membrane BZ16_1993 ENOG4106WZ1 flagella biosynthesis regulator BZ16_1996 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ16_1998 ENOG4105MH2 YfcL protein BZ16_1999 ENOG4108BPE -transporting atpase BZ16_2000 ENOG4105EJ9 Membrane BZ16_2003 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BZ16_2005 ENOG4108BY2 phosphohistidine phosphatase BZ16_2009 ENOG4105KZW UPF0381 protein BZ16_2010 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BZ16_2011 ENOG410903C (LipO)protein BZ16_2012 ENOG4105KWW Biogenesis protein BZ16_2013 ENOG4105KWW Biogenesis protein BZ16_2014 ENOG4107QX9 Thiol disulfide interChange protein BZ16_2015 ENOG4105DA4 cytochrome c-type biogenesis protein BZ16_2017 ENOG4105X3C heme exporter protein BZ16_2018 ENOG41060IM Heme exporter protein BZ16_2019 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BZ16_202 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA BZ16_2023 ENOG4108V0P LemA family BZ16_2025 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BZ16_203 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BZ16_2031 ENOG4105CS6 Rhs element vgr protein BZ16_204 ENOG4105C34 Pseudouridine synthase BZ16_2040 ENOG4105CW0 outer membrane usher protein BZ16_2041 ENOG4105GQR Chaperone BZ16_2043 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ16_205 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ16_2053 ENOG4105CVE Lytic murein transglycosylase BZ16_2059 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ16_206 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ16_2061 ENOG4107QY8 reductase BZ16_2062 ENOG4105QAX Iron-sulfur BZ16_2063 ENOG4107KGK dmso reductase anchor subunit BZ16_2064 ENOG4108NEM leader-binding protein dmsD BZ16_2066 ENOG4107Y60 (LipO)protein BZ16_2068 ENOG4106B0W Curli production assembly transport component CsgG BZ16_2070 ENOG4108VKM cytochrome b561 BZ16_2071 ENOG4105CHM Aminotransferase BZ16_2072 ENOG41072TH Protein of unknown function (DUF1479) BZ16_2075 ENOG4105C5Q Transcriptional regulator BZ16_2076 ENOG4105CPC Aldo Keto reductase BZ16_2079 ENOG4105D9N nucleoside BZ16_2090 ENOG4105VRT cytoplasmic protein BZ16_2093 ENOG4105EXN Sulfate transport protein CysZ BZ16_2094 ENOG4105C6T cysteine synthase BZ16_2095 ENOG4105KZ7 phosphocarrier protein hpr BZ16_2097 ENOG4105C5Y PTS System BZ16_2098 ENOG4105E0F Histidine kinase BZ16_2099 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ16_2100 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ16_2103 ENOG4105E1V na solute symporter BZ16_2105 ENOG4107RAQ aminopeptidase BZ16_2106 ENOG4105C87 Aminotransferase class I and II BZ16_2108 ENOG41062D9 Histidine kinase BZ16_2109 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ16_2111 ENOG4105C6T cysteine synthase BZ16_2113 ENOG4105ECW sulfate abc transporter BZ16_2114 ENOG4108I5D sulfate abc transporter BZ16_2115 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein BZ16_2117 ENOG4105QEK Transcriptional regulator BZ16_2118 ENOG4108R66 Conserved Protein BZ16_2123 ENOG4105EZR dyp-type peroxidase family protein BZ16_2124 ENOG4105E7K (LipO)protein BZ16_2125 ENOG4105H4F exported protein BZ16_213 ENOG4105T42 (LipO)protein BZ16_2136 ENOG4105C6K Malic enzyme BZ16_2138 ENOG4105CUW cytochrome C-TYPE protein BZ16_2139 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) BZ16_214 ENOG4105JIM Phosphatidylserine synthase BZ16_2141 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase BZ16_2142 ENOG4108ZNS ferredoxin-type protein NapF BZ16_2143 ENOG4105WH1 Two component transcriptional regulator luxr family BZ16_2145 ENOG4105BZS acriflavin resistance protein BZ16_2147 ENOG4105S2T inner membrane protein YbcI BZ16_2148 ENOG4105C4X radical SAM domain protein BZ16_2149 ENOG4105ENH Sulfatase BZ16_215 ENOG4105CD5 CoA-binding domain protein BZ16_2150 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ16_2151 ENOG4107Z33 ABC transporter, permease BZ16_2152 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC BZ16_2154 ENOG4105KUZ arsenate reductase BZ16_216 ENOG4106IUH DTW domain containing protein BZ16_2160 ENOG4105CGZ zinc metallopeptidase BZ16_2162 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ16_2164 ENOG4105RH4 Glycine cleavage system transcriptional repressor BZ16_2165 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BZ16_2168 ENOG4105C02 permease BZ16_2169 ENOG4105ERG peptidase m48, ste24p BZ16_217 ENOG4105K63 Thioredoxin BZ16_2170 ENOG4105K89 arsenate reductase BZ16_2172 ENOG4105C2W permease BZ16_2175 ENOG4108V3E phosphoribosylglycinamide formyltransferase BZ16_2176 ENOG4108MK9 spermidine N(1)-acetyltransferase BZ16_2177 ENOG4108C80 FliB family BZ16_2179 ENOG4105E2Z phosphate ABC transporter (Permease BZ16_218 ENOG4105EIB trna rrna methyltransferase BZ16_2180 ENOG4105C8U phosphate abc transporter BZ16_2181 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BZ16_2182 ENOG4105C9X ppx gppa phosphatase BZ16_2183 ENOG4105CJW magnesium transporter BZ16_2184 ENOG4105R8A Heat shock protein BZ16_2186 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BZ16_2187 ENOG4105F38 ABC transporter, permease BZ16_2189 ENOG4108JPW Aminotransferase BZ16_219 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ16_2191 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ16_2196 ENOG4105EB3 Histidine kinase BZ16_2197 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ16_2198 ENOG4105KWI UPF0339 protein BZ16_2199 ENOG4105CFP Peptidase U32 BZ16_220 ENOG4105CW7 secretion protein, HlyD family BZ16_2201 ENOG4108ZGU inhibitor of vertebrate lysozyme BZ16_2203 ENOG4105DWF phosphomethylpyrimidine kinase BZ16_221 ENOG4105NTK Transcriptional repressor Mpra BZ16_2210 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ16_2212 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BZ16_2214 ENOG4105VPD cellular component movement BZ16_2217 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ16_2218 ENOG4105N21 Membrane BZ16_222 ENOG4105ZED uncharacterized protein ygaH BZ16_2226 ENOG4108MGN ATP-binding component of a transport system BZ16_2227 ENOG4108MGN ATP-binding component of a transport system BZ16_2228 ENOG4105YYA enhanced serine sensitivity protein SseB BZ16_223 ENOG4108UMN azlc family BZ16_2230 ENOG4105WVQ Fe-S assembly protein IscX BZ16_2231 ENOG4108ZIT Ferredoxin, 2FE-2S BZ16_2235 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BZ16_2236 ENOG4105C3J Cysteine desulfurase BZ16_224 ENOG4105EQ0 Major Facilitator superfamily BZ16_2240 ENOG4105D7X high-affinity nickel-transporter BZ16_2241 ENOG41065CD Exported protein BZ16_2242 ENOG4105D8G Major Facilitator superfamily BZ16_2243 ENOG4108MN2 Stationary phase inducible protein CsiE BZ16_2246 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ16_2247 ENOG4108M21 BZ16_2248 ENOG4108YZA Nitrogen regulatory protein pii BZ16_2249 ENOG4105C4K Nad synthetase BZ16_2250 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ16_2251 ENOG4108SKK alpha helix protein BZ16_2252 ENOG4107WP9 Histidine kinase BZ16_2257 ENOG4108Z6B deaminase BZ16_2258 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB BZ16_2260 ENOG4106G6Q Transcriptional regulator BZ16_2261 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BZ16_2267 ENOG4105C3F Signal peptidase i BZ16_2270 ENOG4105WMJ Positive regulator of sigma E, RseC MucC BZ16_2271 ENOG4105VQK sigma E regulatory protein, MucB RseB BZ16_2272 ENOG41069PW sigma-e factor negative regulatory protein BZ16_2274 ENOG4108IYU L-aspartate oxidase BZ16_2276 ENOG4105C1J atp-dependent rna helicase BZ16_2287 ENOG4107R7A Allophanate hydrolase subunit 2 BZ16_2288 ENOG4105P4J Allophanate hydrolase, subunit 1 BZ16_229 ENOG4105F87 Dehydratase BZ16_2290 ENOG4107QNR UPF0135 protein BZ16_2291 ENOG4107RF4 Phosphodiesterase BZ16_2292 ENOG4105CVP deoxyribo-dipyrimidine photolyase BZ16_2293 ENOG4107SEY Conserved Protein BZ16_2294 ENOG4105XIQ Protein of unknown function (DUF2517) BZ16_2298 ENOG4105C08 Histidine kinase BZ16_2299 ENOG4105EEX Two component transcriptional regulator (Winged helix family BZ16_2303 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 BZ16_2308 ENOG4105EZV Transcriptional regulator BZ16_2309 ENOG4105VCP PTS System BZ16_231 ENOG4105E5Q amino acid AbC transporter BZ16_2310 ENOG4105CK1 PTS System BZ16_2311 ENOG4105VZJ PTS System BZ16_2313 ENOG41086WQ Protein CrcB homolog BZ16_2314 ENOG4107SVH Potassium channel protein BZ16_2315 ENOG4105XXV Acid-resistance protein BZ16_2319 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) BZ16_2326 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) BZ16_2327 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) BZ16_2328 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ16_2329 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ16_233 ENOG4105C5R Aminotransferase BZ16_2330 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BZ16_2331 ENOG4105VEQ Cold shock protein BZ16_2333 ENOG4108SAJ Protein of unknown function (DUF1198) BZ16_2334 ENOG4108WMJ Protein of unknown function (DUF2002) BZ16_2339 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ16_2340 ENOG4108IJ7 Glycine betaine BZ16_2341 ENOG4108HQS Glycine betaine BZ16_2342 ENOG4105GIJ Glycine betaine BZ16_2344 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BZ16_2346 ENOG4108JDX DNA polymerase iii, epsilon subunit BZ16_2348 ENOG4105D1A Methyltransferase BZ16_2350 ENOG4105E9H Lytic Murein transglycosylase BZ16_2353 ENOG4105CV8 reductase BZ16_2359 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BZ16_236 ENOG4105CHM Aminotransferase BZ16_2361 ENOG4108UMI ABC transporter, permease BZ16_2362 ENOG4105D01 (LipO)protein BZ16_2363 ENOG4108R8X outer membrane lipoprotein BZ16_2364 ENOG4108R96 Methyltransferase, YaeB family BZ16_2366 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BZ16_2367 ENOG4108YZN class I peptide chain release factor BZ16_2368 ENOG4108VWS Yaeq family BZ16_2370 ENOG4105M1T rho-binding antiterminator BZ16_2373 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BZ16_2375 ENOG4105C0B DNA polymerase III (alpha subunit) BZ16_2377 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BZ16_2381 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) BZ16_2383 ENOG4105DZP Membrane-associated zinc metalloprotease BZ16_2384 ENOG4105KNE Phosphatidate cytidylyltransferase BZ16_2385 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BZ16_2391 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ16_2395 ENOG4105QDK Flavodoxin BZ16_2396 ENOG4105DR9 pseudouridine synthase BZ16_2397 ENOG4105WP7 tRNA pseudouridine synthase C BZ16_2401 ENOG4105EWT decarboxylase family BZ16_2404 ENOG4105M08 Membrane BZ16_2405 ENOG4105ETT transcriptional Regulator, LysR family BZ16_2407 ENOG4105C9B Cysteine desulfurase BZ16_2408 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BZ16_2409 ENOG4105CUZ uba thif-type nad fad binding protein BZ16_2410 ENOG4105CA3 membrane-bound lytic murein transglycosylase BZ16_2414 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ16_2416 ENOG4107QYX exodeoxyribonuclease v alpha BZ16_2417 ENOG4107QKA exodeoxyribonuclease V beta BZ16_2418 ENOG4107QXK peptidase BZ16_2419 ENOG4105DSY exodeoxyribonuclease V, gamma BZ16_2427 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BZ16_2430 ENOG4105CPC Aldo Keto reductase BZ16_2436 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BZ16_2437 ENOG41060NJ transcriptional regulator BZ16_2438 ENOG4105F27 Major Facilitator BZ16_2439 ENOG4105RQF LysR family Transcriptional regulator BZ16_244 ENOG4106YJS accessory processing protein BZ16_2440 ENOG4105EJC lysr family transcriptional regulator BZ16_2442 ENOG4105C8Q Methyl-accepting chemotaxis BZ16_2455 ENOG4105D7Q type ii secretion system BZ16_2456 ENOG4107QHF type ii secretion system protein e BZ16_246 ENOG4107QPN acyl-Coa dehydrogenase BZ16_2460 ENOG4107B2H carbonic anhydrase BZ16_2465 ENOG4105CBG Sulfatase BZ16_2466 ENOG4105E98 transcriptional regulator DeoR family BZ16_2467 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of BZ16_2468 ENOG4105E70 isomerase BZ16_2469 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB BZ16_2470 ENOG4105ETZ PTS System BZ16_2471 ENOG4105F3R pts system mannose fructose sorbose family iid BZ16_2472 ENOG4108YTN IIa component BZ16_2473 ENOG4105CE4 GlcNAc 6-P deacetylase BZ16_2474 ENOG4105CHR reductase BZ16_2476 ENOG4105C4X radical SAM domain protein BZ16_2477 ENOG4105ENH Sulfatase BZ16_2479 ENOG4105D2N Aldolase BZ16_248 ENOG4105F7V ErfK ybiS ycfS ynhG family protein BZ16_2482 ENOG4105ETE Transcriptional regulator (LacI family BZ16_2483 ENOG4105DPW Major facilitator superfamily MFS_1 BZ16_2485 ENOG4105ETE Transcriptional regulator (LacI family BZ16_2487 ENOG4105CI1 PTS System BZ16_2488 ENOG4105C4C beta-galactosidase BZ16_249 ENOG4105E7A Glutamine amidotransferase BZ16_2490 ENOG4105EG2 ABC transporter, permease BZ16_2492 ENOG4107FKK extracellular solute-binding protein family 1 BZ16_2495 ENOG4105CNN ABC, transporter BZ16_2496 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ16_2498 ENOG4108UY0 (LipO)protein BZ16_2499 ENOG4105NTW Transcriptional regulator BZ16_25 ENOG41064T2 transcriptional regulator, lysR family BZ16_250 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ16_251 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ16_2516 ENOG4105WJ3 XRE family Transcriptional regulator BZ16_2517 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation BZ16_252 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ16_2521 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ16_2533 ENOG4105VZ1 Replication Protein BZ16_2535 ENOG4105ED4 portal protein BZ16_2559 ENOG4105DFP Integrase BZ16_256 ENOG4105CJ2 (LipO)protein BZ16_2563 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BZ16_2564 ENOG4105T95 Thiol disulfide interChange protein BZ16_2565 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ16_2566 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) BZ16_2567 ENOG4105CT7 inner membrane cred family protein BZ16_2568 ENOG4105EB3 Histidine kinase BZ16_2569 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ16_2570 ENOG4105Y75 tpr repeat protein BZ16_2573 ENOG4108UT2 hemolysin iii BZ16_2580 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ16_2581 ENOG4105D0A hydroxylase BZ16_2582 ENOG4107RAQ aminopeptidase BZ16_2585 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BZ16_2586 ENOG4108JQ1 Dehydrogenase BZ16_2587 ENOG4105E66 phosphoriboisomerase A BZ16_2589 ENOG4105MPN Membrane BZ16_2591 ENOG4105D64 Mechanosensitive ion channel BZ16_2592 ENOG4105D2N Aldolase BZ16_2595 ENOG4105CV1 Transketolase (EC 2.2.1.1) BZ16_2596 ENOG4108K0D peptidase, M48 BZ16_2598 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BZ16_26 ENOG4108IQE Amp-dependent synthetase and ligase BZ16_260 ENOG4105CIN aminoacyl-histidine dipeptidase BZ16_2602 ENOG4105RWS endonuclease I BZ16_2603 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BZ16_2604 ENOG4105D7Z glutathione synthase BZ16_2607 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) BZ16_2609 ENOG4105CZX twitching motility protein BZ16_2610 ENOG4105DFA alanine racemase domain protein BZ16_2611 ENOG4105II7 pyrroline-5-carboxylate reductase BZ16_2612 ENOG4108VIA integral membrane protein BZ16_2614 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BZ16_2615 ENOG4105CSA Coproporphyrinogen iii oxidase BZ16_2616 ENOG4105EUK rtx toxin RtxA BZ16_2617 ENOG4105K33 Periplasmic Protein BZ16_2618 ENOG4105CSV Glutaminase BZ16_2619 ENOG41090ED Protein with unknown function (DUF469) BZ16_2621 ENOG4105CEN a g-specific adenine glycosylase BZ16_2626 ENOG4105CNN ABC, transporter BZ16_2627 ENOG4105C2J ABC transporter BZ16_2628 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ16_2629 ENOG4105CXN decarboxylase BZ16_2643 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ16_2645 ENOG4105CDV Ompa motb domain protein BZ16_2663 ENOG4105DUU IucA IucC family protein BZ16_2664 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ16_2666 ENOG4105CT4 transporter BZ16_2668 ENOG4105ETE Transcriptional regulator (LacI family BZ16_2669 ENOG4105C8P )-transporter BZ16_2670 ENOG41062WK cellular response to acidity BZ16_2675 ENOG4105CNA YD repeat protein BZ16_2680 ENOG4105CNA YD repeat protein BZ16_2682 ENOG4105CS6 Rhs element vgr protein BZ16_2685 ENOG4107EFN gluconate transport system permease 3 BZ16_2689 ENOG4105BZ1 (ABC) transporter BZ16_2695 ENOG4105C0W non-ribosomal peptide synthetase BZ16_2696 ENOG4105C0W non-ribosomal peptide synthetase BZ16_2697 ENOG4107ZSV Receptor BZ16_2698 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BZ16_2699 ENOG4105CFC Transporter BZ16_27 ENOG4105C7K acetolactate synthase BZ16_2700 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway BZ16_2705 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ16_2706 ENOG4105BZU Histidine kinase BZ16_2708 ENOG4105DQ6 Transposase BZ16_2709 ENOG4108XTF Outer Membrane Lipoprotein BZ16_271 ENOG4105F2W methyltransferase BZ16_2714 ENOG4107RD7 Flagellar Motor Protein, MotA BZ16_2720 ENOG410804A Flagellar hook-associated 2 domain-containing protein BZ16_2721 ENOG4105I03 Flagellin BZ16_2722 ENOG4105I03 Flagellin BZ16_2723 ENOG4108M3R transcriptional activator CadC BZ16_2727 ENOG4105E1Q flagellar hook-associated protein BZ16_2731 ENOG4105CGA flagellar basal-body rod protein FlgG BZ16_2732 ENOG4108KPB Flagellar basal-body rod protein FlgF BZ16_2733 ENOG4105BZE flagellar hook protein, FlgE BZ16_2734 ENOG4105W00 Flagellar hook capping protein BZ16_2735 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ16_2736 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ16_2737 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA BZ16_2741 ENOG4108JIR Flagellum-specific ATP synthase BZ16_2744 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ16_2746 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ16_2748 ENOG4105DD5 Flagellar motor switch protein BZ16_2749 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ16_2750 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ16_2751 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ16_2752 ENOG4105D00 flagellar biosynthetic protein flhB BZ16_2756 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein BZ16_2758 ENOG4106P2F Pfam:Pili_assembly_C BZ16_2759 ENOG4106PG1 outer membrane usher protein BZ16_276 ENOG4105DKQ ROK family BZ16_2761 ENOG4105E03 chitinase BZ16_2762 ENOG4108M1A Chitin-binding protein BZ16_277 ENOG4105EYH Exonuclease BZ16_2779 ENOG4108ZZF transport protein (ExbD) BZ16_278 ENOG4107RH8 nuclease SbcCD subunit D BZ16_2781 ENOG4105CWK Biopolymer transport protein, ExbB BZ16_2782 ENOG4105C28 cystathionine BZ16_2783 ENOG4108K81 inner membrane protein YghB BZ16_2784 ENOG4105CF7 AraC family transcriptional regulator BZ16_2785 ENOG4108I6A alcohol dehydrogenase BZ16_2786 ENOG4105CV8 reductase BZ16_2788 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) BZ16_2789 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase BZ16_279 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BZ16_2790 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ16_2791 ENOG4105NF4 modulator of drug activity BZ16_2792 ENOG4105CR8 Transcriptional regulator BZ16_2793 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ16_2794 ENOG4105IPS esterase BZ16_2795 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BZ16_2796 ENOG4108SX3 cytoplasmic protein BZ16_2797 ENOG41087AY ADP-Ribose pyrophosphatase BZ16_2798 ENOG4105DFG type I secretion outer membrane protein BZ16_28 ENOG4108ZP8 Acetolactate synthase small subunit BZ16_280 ENOG4105BZU Histidine kinase BZ16_2801 ENOG4106032 Glutathionylspermidine synthase BZ16_2802 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BZ16_2804 ENOG4105W0Z cytoplasmic protein BZ16_2805 ENOG4105DVH amino acid BZ16_2808 ENOG4105I7R Adenylate cyclase BZ16_2809 ENOG4106MWK domain protein BZ16_2812 ENOG4107ZVW dihydroneopterin aldolase BZ16_2815 ENOG4105VCC 30S ribosomal protein S21 BZ16_2816 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BZ16_2817 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ16_282 ENOG4105CWM branched-chain amino acid transport system II carrier protein BZ16_2824 ENOG4108X9F tail fiber protein BZ16_283 ENOG4105C85 amino acid BZ16_284 ENOG4107R28 alpha amylase, catalytic region BZ16_2842 ENOG4105ED4 portal protein BZ16_285 ENOG4105CHR reductase BZ16_2850 ENOG4105MEH BZ16_2853 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ16_2866 ENOG4105KME endoribonuclease L-psp BZ16_287 ENOG4105D3R alkyl hydroperoxide reductase BZ16_2870 ENOG4105CHM Aminotransferase BZ16_2873 ENOG4105J12 Multidrug resistance protein mdtN BZ16_2874 ENOG4108MI0 Resistance protein BZ16_2876 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ16_2878 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BZ16_288 ENOG4108ZYK Acyl carrier protein phosphodiesterase BZ16_2880 ENOG4108IJG ABC transporter substrate-binding protein BZ16_2881 ENOG4107KJX Transcriptional regulator BZ16_2882 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 BZ16_2887 ENOG4105CKT filamentous hemagglutinin BZ16_2896 ENOG4105CKT filamentous hemagglutinin BZ16_2898 ENOG4105CKT filamentous hemagglutinin BZ16_29 ENOG4107B7Y DNA-binding transcriptional regulator FruR BZ16_2900 ENOG4105CKT filamentous hemagglutinin BZ16_2901 ENOG4105D5K Hemolysin activator protein BZ16_2902 ENOG4108M24 von Willebrand factor, type A BZ16_2904 ENOG4108M24 von Willebrand factor, type A BZ16_2905 ENOG4108M24 von Willebrand factor, type A BZ16_2908 ENOG4108YK4 Acid-resistance membrane protein BZ16_2909 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ16_291 ENOG4105VIE preprotein translocase, subunit YajC BZ16_2912 ENOG4108VKG metal-dependent hydrolase BZ16_2913 ENOG4105EE0 oxidoreductase BZ16_2915 ENOG4105P66 Membrane BZ16_2916 ENOG4105CTX dehydratase BZ16_2917 ENOG4107QZW Altronate oxidoreductase BZ16_2919 ENOG4105DPW Major facilitator superfamily MFS_1 BZ16_292 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ16_2922 ENOG4106W5V Membrane BZ16_2925 ENOG4105NE1 Conserved Protein BZ16_2926 ENOG41090KG Inner membrane protein YqjE BZ16_2928 ENOG4108VBZ doxx family BZ16_2929 ENOG4105CHF Glutathione S-transferase BZ16_293 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ16_2930 ENOG4105CWB LysR family transcriptional Regulator BZ16_2931 ENOG4108CNN domain protein BZ16_2932 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BZ16_2936 ENOG4105W4M Transport-associated protein BZ16_2938 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BZ16_2939 ENOG4105BZU Histidine kinase BZ16_2941 ENOG4105N5T Radical SAM Protein BZ16_2942 ENOG4105CBC glutamate synthase BZ16_2943 ENOG4105BZ8 glutamate synthase BZ16_2945 ENOG4105KB2 stringent starvation protein b BZ16_2946 ENOG4107MKT Stringent starvation protein a BZ16_2949 ENOG4105D6Z AFG1 family ATPase BZ16_2950 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III BZ16_2951 ENOG4105C0H protease BZ16_2952 ENOG4105C0H protease BZ16_2954 ENOG4105VFK BolA family BZ16_2955 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane BZ16_2956 ENOG4105E3I toluene tolerance BZ16_2957 ENOG4107PE3 Mammalian cell entry related domain protein BZ16_2958 ENOG4105CY3 ABC transporter, permease BZ16_2959 ENOG4105DHJ ABC, transporter BZ16_296 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BZ16_2960 ENOG4105FEU K -dependent Na -Ca exchanger BZ16_2961 ENOG4105C2X Arabinose 5-phosphate isomerase BZ16_2962 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BZ16_2963 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) BZ16_2964 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BZ16_2965 ENOG4108IUZ ABC transporter BZ16_2966 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ16_2967 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BZ16_2968 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BZ16_2970 ENOG41080Z8 PHOSPHOCARRIER protein BZ16_2973 ENOG4105KME endoribonuclease L-psp BZ16_2975 ENOG4105D4X repressor BZ16_2976 ENOG4105C5Y PTS System BZ16_2977 ENOG4105CG3 alpha amylase, catalytic region BZ16_2978 ENOG4105NXH GreA GreB family elongation factor BZ16_2979 ENOG4108XVM Cytochrome b(562) BZ16_2981 ENOG4105CMS peptidase U62, modulator of DNA gyrase BZ16_2983 ENOG4105UNR (Barnase) inhibitor BZ16_2989 ENOG4105CR8 Transcriptional regulator BZ16_299 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BZ16_2998 ENOG4105D1U peptidase U62 modulator of DNA gyrase BZ16_30 ENOG4108RNS Exports L-alanine (By similarity) BZ16_300 ENOG4108ZAI phosphatidylglycerophosphatase a BZ16_3000 ENOG4105QD6 exported protein BZ16_3001 ENOG4105C03 ribonuclease BZ16_3003 ENOG4105VQ7 Rod shape-determining protein MreD BZ16_3004 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BZ16_3005 ENOG4105DFF Rod shape-determining protein mreb BZ16_3006 ENOG41062P1 Diguanylate cyclase phosphodiesterase BZ16_3007 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family BZ16_3011 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BZ16_3012 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BZ16_3014 ENOG4105RG0 Membrane BZ16_3015 ENOG4108IA2 Sodium pantothenate symporter BZ16_3017 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ16_3018 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BZ16_302 ENOG4105CTB Polyprenyl synthetase BZ16_3021 ENOG4105CSH Transporter BZ16_3022 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BZ16_3025 ENOG4108XTF Outer Membrane Lipoprotein BZ16_3026 ENOG4105VEQ Cold shock protein BZ16_3027 ENOG4105VEQ Cold shock protein BZ16_3028 ENOG4105VEQ Cold shock protein BZ16_3031 ENOG4105CYM Glutathione S-transferase BZ16_3032 ENOG4105C2X Arabinose 5-phosphate isomerase BZ16_3033 ENOG4105EF1 ribulokinase BZ16_3035 ENOG4105CNN ABC, transporter BZ16_3036 ENOG4105C2J ABC transporter BZ16_3038 ENOG4105D1S lipid A biosynthesis BZ16_3040 ENOG4105EEQ Na H antiporter BZ16_3041 ENOG4105C7N Xanthine uracil vitamin C permease BZ16_3044 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BZ16_3046 ENOG4105GVF (ABC) transporter BZ16_3048 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ16_3049 ENOG4108RVA ribokinase BZ16_305 ENOG4107S0N DJ-1 family BZ16_3050 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BZ16_3052 ENOG4107TYG Oxidoreductase domain-containing protein BZ16_3054 ENOG4105CS6 Rhs element vgr protein BZ16_3056 ENOG4105CNA YD repeat protein BZ16_3058 ENOG4105CS6 Rhs element vgr protein BZ16_306 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BZ16_3064 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ16_3074 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ16_3076 ENOG4107W52 maltose operon periplasmic protein BZ16_308 ENOG4107RDB Major Facilitator BZ16_3080 ENOG4107FKK extracellular solute-binding protein family 1 BZ16_3081 ENOG4105D56 permease protein BZ16_3082 ENOG4105EG2 ABC transporter, permease BZ16_3085 ENOG4105CFH Aspartokinase BZ16_3088 ENOG4105C3R Methionine synthase BZ16_3089 ENOG41069M3 Transcriptional regulator BZ16_3091 ENOG4108I9X Isocitrate lyase BZ16_3092 ENOG4107QP3 malate synthase g BZ16_310 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BZ16_3104 ENOG4108Z0R Transferase BZ16_3107 ENOG4108WI1 Dna topoisomerase BZ16_3109 ENOG4105C79 DNA protecting protein DprA BZ16_311 ENOG4105CCU oxidase (Subunit III) BZ16_3113 ENOG4105C1A potassium transporter peripheral membrane BZ16_3115 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system BZ16_3116 ENOG4105W1Y Transcriptional regulator BZ16_3119 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BZ16_312 ENOG4105BZ9 Cytochrome C oxidase, subunit I BZ16_3122 ENOG41067V7 50S ribosomal protein L36 BZ16_3123 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BZ16_3125 ENOG4105VPB 50S ribosomal protein L30 BZ16_313 ENOG4105E2S oxidase) subunit II BZ16_3134 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BZ16_3136 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BZ16_3137 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BZ16_3139 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BZ16_314 ENOG4108NFH Sugar hydrolase BZ16_3149 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BZ16_315 ENOG4105EYM Major Facilitator superfamily BZ16_3154 ENOG4105WWK YheO domain protein BZ16_3155 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ16_3157 ENOG4108YZY peptidylprolyl cis-trans isomerase BZ16_3158 ENOG4105VKU nucleicacid-binding protein BZ16_316 ENOG4105IEY (LipO)protein BZ16_3161 ENOG4105C5H ABC transporter BZ16_3162 ENOG4105K64 Glycosyl transferase, family 2 BZ16_3164 ENOG4105E2B Taurine dioxygenase BZ16_3165 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ16_3167 ENOG4106FTQ Taurine ABC transporter, periplasmic BZ16_3169 ENOG4105DNZ Alpha Beta Hydrolase BZ16_317 ENOG4105M85 Bola protein BZ16_3171 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) BZ16_3173 ENOG4108UKZ OsmC family BZ16_3175 ENOG410613R integral membrane protein, YccS YhfK family BZ16_3176 ENOG4105C8Y Acetylornithine aminotransferase BZ16_3178 ENOG4105D7A ATP-binding protein BZ16_3179 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ16_3181 ENOG4105F8D glycoside hydrolase family 4 BZ16_3182 ENOG41060NJ transcriptional regulator BZ16_3185 ENOG4105DZC cytosine deaminase BZ16_3186 ENOG4107QZF nitrite reductase NADPH large subunit BZ16_3187 ENOG4105WZK nitrite reductase NADPH small subunit BZ16_3188 ENOG4107V9H nitrite transporter BZ16_3190 ENOG4105C31 Tryptophanyl-tRNA synthetase BZ16_3192 ENOG4105DJV ribulose-phosphate 3-epimerase BZ16_3197 ENOG4105E4G Type IV pilus BZ16_3202 ENOG4108JQC penicillin-binding protein 1A BZ16_3203 ENOG4107RK2 ADP-ribose diphosphatase NudE BZ16_3205 ENOG4105DQY intracellular growth attenuator BZ16_3206 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 BZ16_3207 ENOG4105VEJ Heat shock protein BZ16_3210 ENOG4105E0F Histidine kinase BZ16_3211 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ16_3212 ENOG4108RRZ Transcription elongation factor GreB BZ16_3213 ENOG4105BZM domain protein BZ16_3214 ENOG4105XFK Ferrous iron transport protein A BZ16_3215 ENOG4105CE1 Ferrous iron transport protein b BZ16_3217 ENOG4105RID UPF0379 protein yhcN BZ16_3219 ENOG4105MJ2 Competence protein BZ16_322 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BZ16_3221 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) BZ16_3222 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ16_3226 ENOG4105E98 transcriptional regulator DeoR family BZ16_3229 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BZ16_323 ENOG4105K70 DNA-binding protein BZ16_3230 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ16_3235 ENOG4108HRK Histidine kinase BZ16_324 ENOG4105EIN peptidylprolyl cis-trans isomerase BZ16_3240 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ16_3242 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BZ16_3245 ENOG4105GMB type VI secretion system effector, hcp1 family BZ16_3246 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ16_3247 ENOG4105C6Z Gluconate BZ16_3248 ENOG4105DIQ Transcriptional regulator BZ16_3249 ENOG4105C2I pirin domain protein BZ16_325 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BZ16_3251 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ16_3253 ENOG4105D2N Aldolase BZ16_3255 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ16_3256 ENOG4105CNN ABC, transporter BZ16_326 ENOG4108TGP Thioesterase superfamily protein BZ16_3274 ENOG4105CBX hi0933 family BZ16_3275 ENOG4105CJ3 phosphate transporter BZ16_3277 ENOG4108M6U Universal stress protein A BZ16_328 ENOG4108NFA extracellular solute-binding protein BZ16_3281 ENOG4105DGW oligopeptidase A BZ16_3282 ENOG4105D6S protein involved in catabolism of external DNA BZ16_3283 ENOG4105DC8 reductase BZ16_3284 ENOG4107VHA regulatoR BZ16_3285 ENOG4107QQ0 gntp family BZ16_3286 ENOG4105BZW Glycerate kinase BZ16_3291 ENOG4107H3J ribonuclease BZ16_3292 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) BZ16_3293 ENOG41066T0 asmA family BZ16_3294 ENOG4105CMB EAL domain-containing protein BZ16_3295 ENOG4105VSH 4-oxalocrotonate tautomerase BZ16_3296 ENOG4107SS6 2-dehydro-3-deoxygluconokinase BZ16_3297 ENOG4105CS0 peptidase BZ16_33 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BZ16_330 ENOG4105C6T cysteine synthase BZ16_3302 ENOG4108PU9 oligogalacturonate-specific porin BZ16_3303 ENOG4105BZU Histidine kinase BZ16_3304 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BZ16_3305 ENOG4108JQ7 (ABC) transporter BZ16_3306 ENOG4105C3U ABC transporter BZ16_3307 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ16_3308 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ16_3309 ENOG4105DEF Extracellular solute-binding protein, family 5 BZ16_331 ENOG4108XM1 transcriptional regulator AsnC family BZ16_3311 ENOG4105D5K Hemolysin activator protein BZ16_3315 ENOG4105CXY transporter BZ16_3316 ENOG4105BZU Histidine kinase BZ16_3317 ENOG4108KX4 response regulator BZ16_3318 ENOG4105DIJ Phosphoethanolamine transferase BZ16_332 ENOG4105BZ1 (ABC) transporter BZ16_3320 ENOG4105C85 amino acid BZ16_3323 ENOG4105C6T cysteine synthase BZ16_3329 ENOG4105CM4 permease protein BZ16_333 ENOG4105BZ1 (ABC) transporter BZ16_3331 ENOG4108IPW abc transporter atp-binding protein BZ16_3334 ENOG4105DFP Integrase BZ16_3336 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures BZ16_3338 ENOG4108XS9 dna repair protein BZ16_334 ENOG4108YZA Nitrogen regulatory protein pii BZ16_3346 ENOG4106H3A restriction BZ16_3348 ENOG4105DZR Type I site-specific deoxyribonuclease BZ16_335 ENOG4105BZU Histidine kinase BZ16_3350 ENOG4107XZC Restriction modification system DNA (Specificity BZ16_3354 ENOG4105DFP Integrase BZ16_3356 ENOG4105T16 Transcriptional regulator (AraC family) BZ16_3357 ENOG4107RNG ABC transporter BZ16_3359 ENOG4105DFW ABC transporter BZ16_336 ENOG4105C29 acyl-CoA thioesterase BZ16_3361 ENOG4105CMG Carbohydrate kinase BZ16_3363 ENOG4108TTM chaperone BZ16_3365 ENOG4106EAR Fimbrial protein BZ16_3366 ENOG4105MEV Acyl-transferase BZ16_3368 ENOG4105DQ6 Transposase BZ16_337 ENOG4108MNP Glycoprotein polysaccharide metabolism BZ16_3370 ENOG4105C7B Threonine dehydratase BZ16_3371 ENOG4105D99 atp gtp-binding protein BZ16_3372 ENOG4105R2A (LipO)protein BZ16_3376 ENOG4105JKW Valine--pyruvate aminotransferase BZ16_3378 ENOG4107T9C Alpha amylase catalytic region BZ16_338 ENOG41080UX Methyltransferase BZ16_3381 ENOG4108ZG0 Ompa motb domain protein BZ16_3383 ENOG4108R3E Dna-3-methyladenine glycosylase i BZ16_3386 ENOG4106JH6 (LipO)protein BZ16_3387 ENOG4105CTS PTS system mannitol-specific BZ16_3389 ENOG4105E61 Mannitol repressor protein BZ16_339 ENOG4105KF5 hemolysin expression-modulating protein BZ16_3391 ENOG4108YYI Protein of unknown function (DUF2810) BZ16_3394 ENOG4105C8Q Methyl-accepting chemotaxis BZ16_3395 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ16_3397 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ16_3398 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ16_3399 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BZ16_34 ENOG4105CJN penicillin-binding protein BZ16_340 ENOG4108UKR Biofilm formation regulator YbaJ BZ16_3400 ENOG4108MG3 formate dehydrogenase BZ16_3403 ENOG4105EM7 Selenocysteine-specific translation elongation factor BZ16_3404 ENOG4105D13 transposase BZ16_3410 ENOG4107EJG GntR family transcriptional regulator BZ16_3412 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ16_3413 ENOG4108RVA ribokinase BZ16_3419 ENOG4108VVK transcriptional Regulator, AsnC BZ16_342 ENOG4105YK5 50S ribosomal protein L36 BZ16_3420 ENOG4105QTB Flavodoxin BZ16_3423 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation BZ16_3425 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BZ16_3433 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BZ16_3435 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BZ16_3436 ENOG4105C8U phosphate abc transporter BZ16_3437 ENOG4105E2Z phosphate ABC transporter (Permease BZ16_344 ENOG4105BZS acriflavin resistance protein BZ16_3441 ENOG4106PMH Extracellular solute-binding protein family 3 BZ16_3442 ENOG4105EAD ABC transporter BZ16_3443 ENOG4105DRP amino acid AbC transporter BZ16_3444 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 BZ16_3445 ENOG4105C7N Xanthine uracil vitamin C permease BZ16_345 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ16_3450 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BZ16_3453 ENOG4105VG0 50S ribosomal protein l34 BZ16_3456 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BZ16_3458 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ16_3459 ENOG410667J hydrolase BZ16_346 ENOG4108IG5 Transcriptional regulator BZ16_3462 ENOG4105DQ6 Transposase BZ16_3468 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b BZ16_347 ENOG41090EX DsrE family BZ16_3470 ENOG4105PC1 Conserved Protein BZ16_3471 ENOG4105E27 serine threonine protein kinase BZ16_3472 ENOG4108Z33 Thiol disulfide Interchange Protein BZ16_3473 ENOG4105C2M dna polymerase I BZ16_3476 ENOG4105D4P Coproporphyrinogen iii oxidase BZ16_3477 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ16_3478 ENOG4105CUX Signal transduction histidine kinase BZ16_3479 ENOG4105C5F glutamine synthetase BZ16_348 ENOG4105EGS Mechanosensitive ion channel BZ16_3481 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 BZ16_3484 ENOG4105SUU thioesterase domain BZ16_3485 ENOG4105JV1 AsmA family BZ16_3486 ENOG4105C2W permease BZ16_3487 ENOG4105D6U Sodium Glutamate Symporter BZ16_3488 ENOG4105CB5 ATP-dependent DNA helicase recG BZ16_3489 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase BZ16_3490 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ16_3491 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BZ16_3494 ENOG4105EN6 Membrane BZ16_3495 ENOG4105DSJ YicC domain protein BZ16_35 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BZ16_350 ENOG4105WD1 Membrane BZ16_3500 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BZ16_3503 ENOG4105W0E 50S ribosomal protein L33 BZ16_3507 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BZ16_3508 ENOG4105D16 lipopolysaccharide heptosyltransferase i BZ16_3509 ENOG4105XA0 heptosyltransferase ii BZ16_3511 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BZ16_3513 ENOG4105PXI polysaccharide deacetylase BZ16_3514 ENOG41063SB peptidase BZ16_3516 ENOG4107YZP Rhodanese domain protein BZ16_3517 ENOG4105VW4 glutaredoxin 3 BZ16_352 ENOG4107QMP dna polymerase iii subunits gamma and tau BZ16_3520 ENOG4105D7W serine acetyltransferase BZ16_3521 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BZ16_3522 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ16_3523 ENOG4105E0F Histidine kinase BZ16_3524 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ16_3525 ENOG4105FMW periplasmic BZ16_3530 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BZ16_3532 ENOG4107QPK )-transporter BZ16_3533 ENOG4105JSC dimethylmenaquinone methyltransferase BZ16_3535 ENOG4107F9Y LysR family transcriptional regulator BZ16_3537 ENOG4105EBK exported protein BZ16_3538 ENOG4108VTS Membrane BZ16_3539 ENOG4105DP0 ferredoxin-NADP reductase BZ16_3540 ENOG4105CBT Fructose-1,6-bisphosphatase BZ16_3541 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BZ16_3542 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BZ16_3544 ENOG4108JJA ABC, transporter BZ16_3545 ENOG4108MBX Secretion Protein BZ16_3549 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BZ16_3552 ENOG41063M6 Cell Division Protein BZ16_3553 ENOG4105ETE Transcriptional regulator (LacI family BZ16_3555 ENOG4105C25 Primosomal protein n' BZ16_3557 ENOG4108Z12 YiaAB two helix domain-containing protein BZ16_3558 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) BZ16_3559 ENOG4105C28 cystathionine BZ16_3560 ENOG4105CFH Aspartokinase BZ16_3561 ENOG4105SYT Methylenetetrahydrofolate reductase BZ16_3567 ENOG4105X58 receptor BZ16_3570 ENOG4107QZV Type I secretion membrane fusion protein BZ16_3571 ENOG4105YHG TonB family BZ16_3572 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ16_3573 ENOG4105EHV domain protein BZ16_3575 ENOG4105C5Q Transcriptional regulator BZ16_3578 ENOG4108Y73 Membrane BZ16_3589 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator BZ16_359 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BZ16_3590 ENOG4105C2J ABC transporter BZ16_3591 ENOG4107R9N ABC transporter BZ16_3593 ENOG41062B0 ABC transporter, permease BZ16_3594 ENOG4108WFC UPF0438 protein yifE BZ16_3595 ENOG4105C0P Mg chelatase subunit ChlI BZ16_3597 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit BZ16_3598 ENOG4105CM2 brancheD-chain amino acid aminotransferase BZ16_36 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BZ16_360 ENOG4105FAW cDP-glucose 4,6-dehydratase BZ16_3600 ENOG4105C7B Threonine dehydratase BZ16_3606 ENOG4105EMY transcriptional regulator BZ16_361 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ16_3611 ENOG4108MA7 Inherit from COG: YD repeat protein BZ16_3619 ENOG4108VEV chaperone BZ16_362 ENOG4108SMP Nad-dependent epimerase dehydratase BZ16_3621 ENOG4105CW0 outer membrane usher protein BZ16_3622 ENOG4105GQR Chaperone BZ16_3625 ENOG4105KQ5 peptidylprolyl cis-trans isomerase BZ16_3626 ENOG4105C4R Atp-dependent dna helicase BZ16_3629 ENOG4105K63 Thioredoxin BZ16_3631 ENOG4105ESV Glycosyl transferase, family 4 BZ16_3632 ENOG4105SFE lipopolysaccharide biosynthesis protein BZ16_3633 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BZ16_3634 ENOG4108IJ1 Dehydrogenase BZ16_3635 ENOG4105C1B dTDP-glucose 4-6-dehydratase BZ16_3636 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BZ16_3637 ENOG4108WJ1 acetyltransferase BZ16_3638 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ16_3639 ENOG4105EGZ biosynthesis protein BZ16_3643 ENOG4105C85 amino acid BZ16_3648 ENOG410601J HemY protein BZ16_3649 ENOG4105ECF c-methyltransferase BZ16_3650 ENOG41076E6 Uroporphyrinogen-III Synthase BZ16_3652 ENOG4107T0K Adenylate cyclase BZ16_3657 ENOG4105S7Z (LipO)protein BZ16_3659 ENOG4105CT0 Protein of unknown function, DUF484 BZ16_366 ENOG4107Y2G Glycosyl transferase (Group 1 BZ16_3660 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ16_3661 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant BZ16_3662 ENOG4105C4R Atp-dependent dna helicase BZ16_3664 ENOG4105EQN UPF0261 protein BZ16_3666 ENOG4107QUT magnesium and cobalt transport protein CorA BZ16_3667 ENOG4105FR1 rard protein BZ16_3668 ENOG4108VUY thioesterase Superfamily protein BZ16_3669 ENOG4105HDD phospholipase BZ16_3670 ENOG4105C9U ATP-dependent DNA helicase RecQ BZ16_3671 ENOG4105CCF Lysine exporter protein (Lyse ygga) BZ16_3673 ENOG4108EUD Lysophospholipase BZ16_3674 ENOG4105DQF Hydrolase BZ16_3676 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BZ16_3677 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A BZ16_3679 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BZ16_3680 ENOG4108W1V Lipoprotein BZ16_3681 ENOG4105EX9 Membrane BZ16_3684 ENOG4107FS9 Membrane BZ16_3687 ENOG4105MG3 Membrane BZ16_3688 ENOG4106H78 methyltransferase BZ16_3689 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ16_3689 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ16_369 ENOG4108I2E Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity) BZ16_3690 ENOG4105CAK Cell division ATP-binding protein ftsE BZ16_3691 ENOG4105CRP Part of the ABC transporter FtsEX involved in BZ16_3693 ENOG4105U59 -acetyltransferase BZ16_3694 ENOG4105CP9 extracellular ligand-binding receptor BZ16_3695 ENOG4105C32 Amino acid ABC transporter (Permease) BZ16_3696 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BZ16_3697 ENOG4105C0Z ABC transporter BZ16_3698 ENOG4108IV0 ABC, transporter BZ16_3711 ENOG4107T6V glycerophosphoryl diester phosphodiesterase BZ16_3712 ENOG4105RK9 auxin efflux carrier BZ16_3715 ENOG4105DZ2 Transcriptional regulator BZ16_3716 ENOG4105EMK carboxylate amino acid amine transporter BZ16_3718 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) BZ16_3719 ENOG4108I5U Uridine phosphorylase BZ16_3722 ENOG4108KF1 Membrane BZ16_3723 ENOG4105CGY Dna recombination protein BZ16_3725 ENOG4105JC1 sterol-binding domain protein BZ16_3727 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BZ16_3729 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BZ16_3731 ENOG4105D52 delta-aminolevulinic acid dehydratase BZ16_3732 ENOG4105MDZ Transcriptional activator rfaH BZ16_3734 ENOG4107QK7 reductase BZ16_3738 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BZ16_3739 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BZ16_374 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BZ16_3740 ENOG4108RR8 protoporphyrinogen oxidase BZ16_3747 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BZ16_3755 ENOG4105PM1 preprotein translocase subunit SecE BZ16_3756 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BZ16_376 ENOG4108QY5 Ferric enterobactin transport protein BZ16_3764 ENOG4105D41 biosynthesis protein thiH BZ16_3767 ENOG4105D06 uba thif-type nad fad binding protein BZ16_3769 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BZ16_377 ENOG4107RE1 Inosine-guanosine kinase BZ16_3774 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BZ16_3775 ENOG4105R2J Conserved Protein BZ16_3777 ENOG4108T8B Protein of unknown function (DUF1481) BZ16_3778 ENOG4105C12 Phosphoribosylglycinamide synthetase BZ16_378 ENOG4105CKD glutathione-regulated potassium-efflux system protein BZ16_3786 ENOG4105CMM transposase BZ16_379 ENOG4105EU0 Major facilitator Superfamily BZ16_3791 ENOG41062QD Membrane BZ16_3793 ENOG4105CK2 sodium dicarboxylate symporter BZ16_3794 ENOG4105WH1 Two component transcriptional regulator luxr family BZ16_3795 ENOG4105BZU Histidine kinase BZ16_380 ENOG4105CGH 5'-nucleotidase BZ16_3807 ENOG4108JIR Flagellum-specific ATP synthase BZ16_381 ENOG4105CGH 5'-nucleotidase BZ16_3810 ENOG41063Q7 Type III secretion system protein BZ16_3811 ENOG4108HHI Type III secretion system protein BZ16_3812 ENOG41083GP type iii secretion BZ16_3813 ENOG4108TN6 type iii secretion BZ16_3814 ENOG4108IUF type iii secretion BZ16_3815 ENOG41066VF YeeE YedE family protein BZ16_3816 ENOG4105KSU Redox protein BZ16_3817 ENOG4105EQ2 LysR family Transcriptional regulator BZ16_3818 ENOG4105C44 Serine transporter BZ16_3819 ENOG4105C28 cystathionine BZ16_3821 ENOG4105EHG Permease protein BZ16_3822 ENOG4107R4I Periplasmic binding protein BZ16_3823 ENOG4106QJH hemin transport protein BZ16_3824 ENOG4107ENK receptor BZ16_3825 ENOG4107F3C Hemin uptake protein BZ16_3827 ENOG41090JE Utilization Protein BZ16_3828 ENOG4105D4P Coproporphyrinogen iii oxidase BZ16_3832 ENOG4105DAX Pfam:DUF2983 BZ16_384 ENOG4108Z66 YbaK ebsC protein BZ16_3844 ENOG4108S1B Periplasmic chaperone protein BZ16_385 ENOG4105MBR gumn family BZ16_3851 ENOG41080IJ Diacylglycerol kinase BZ16_3853 ENOG4105MYN Zinc uptake regulation protein BZ16_3854 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ16_3855 ENOG4105P4Z Phage shock protein G BZ16_3856 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BZ16_3857 ENOG4105CDU Replicative dna helicase BZ16_3858 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ16_3859 ENOG4105CGF Aromatic amino acid aminotransferase BZ16_386 ENOG4105C59 p-type ATPase BZ16_3860 ENOG4105MSB protein, conserved in bacteria BZ16_3861 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BZ16_3862 ENOG4108UUM single-stranded DNA-binding protein BZ16_3864 ENOG4105C0A alcohol dehydrogenase BZ16_387 ENOG4108Z6Z Transcriptional regulator BZ16_3877 ENOG4108SIC Transcriptional regulator BZ16_3878 ENOG4105BZ8 glutamate synthase BZ16_3879 ENOG4108RC0 Electron transport protein BZ16_388 ENOG4105G5H Membrane BZ16_3880 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ16_3883 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ16_3888 ENOG4108ZVF (LipO)protein BZ16_3889 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BZ16_389 ENOG4107QX8 SPFH domain, Band 7 family protein BZ16_3891 ENOG4105KPY Small multidrug resistance protein BZ16_3892 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) BZ16_3897 ENOG4105EGS Mechanosensitive ion channel BZ16_39 ENOG4105CNI cell division protein FtsW BZ16_390 ENOG4107QR8 Thioredoxin BZ16_3906 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BZ16_3907 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BZ16_3908 ENOG4105K8N protein family UPF0079, ATPase BZ16_3909 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ16_391 ENOG4105E1F short-chain dehydrogenase reductase BZ16_3913 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BZ16_3914 ENOG4107QJR hflk protein BZ16_3915 ENOG4105EPW hflc protein BZ16_3919 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BZ16_392 ENOG4108UJV acyl-CoA thioesterase i BZ16_3920 ENOG4105C2N RNA methyltransferase TrmH family group 3 BZ16_3921 ENOG4105CSU acyl-Coa dehydrogenase BZ16_3922 ENOG4105WSB biofilm stress and motility protein A BZ16_3923 ENOG4108MXZ Esterase BZ16_3925 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BZ16_3926 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BZ16_3929 ENOG4105FHY Opacity-associated protein A BZ16_393 ENOG4108I0Y (ABC) transporter BZ16_3930 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ16_3932 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BZ16_3933 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BZ16_3934 ENOG4108UUE Transcriptional regulator BZ16_3935 ENOG41061GZ Protein of unknown function (DUF1107) BZ16_3936 ENOG4105C37 (CBS) domain BZ16_3938 ENOG4105CFU surface antigen BZ16_3939 ENOG4105MA0 exported protein BZ16_394 ENOG4105CV6 ABC transporter, permease BZ16_3940 ENOG4108ZHD aig2 family BZ16_3941 ENOG4105F0N pyrophosphate phospho-hydrolase BZ16_3943 ENOG4105DFU Cell wall formation (By similarity) BZ16_3947 ENOG4105HVQ Regulatory factor of maltose metabolism BZ16_3949 ENOG4105EAH synthase BZ16_395 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BZ16_3952 ENOG4105QYV Membrane BZ16_3956 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase BZ16_3957 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BZ16_3958 ENOG4105HBR Rna-binding protein BZ16_396 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BZ16_3960 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BZ16_3961 ENOG4105EEI dihydropteroate synthase BZ16_3967 ENOG4105CHV Transcription elongation factor NusA BZ16_3974 ENOG4105C1J atp-dependent rna helicase BZ16_3977 ENOG4105DEN Luciferase family BZ16_398 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ16_3980 ENOG4105BZS acriflavin resistance protein BZ16_3981 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BZ16_3982 ENOG4106RZ4 Peptidase U32 BZ16_3983 ENOG4105CFP Peptidase U32 BZ16_3984 ENOG4105XPQ lipid carrier protein BZ16_3985 ENOG4108YYD acetyltransferase BZ16_3990 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BZ16_3991 ENOG4105DRS transport system, permease BZ16_3995 ENOG4105K4T epimerase BZ16_3996 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein BZ16_3997 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) BZ16_3998 ENOG4105FD8 phosphonate metabolism protein PhnM BZ16_3999 ENOG4105HRV phosphonate c-p lyase system protein phnl BZ16_400 ENOG4105WQ3 Rna-binding protein BZ16_4000 ENOG4105ENV phosphonate C-P lyase system protein PhnK BZ16_4001 ENOG4105FT8 Phosphonate metabolism BZ16_4002 ENOG4105EKV Phosphonate metabolism protein BZ16_4003 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH BZ16_4004 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG BZ16_4005 ENOG4107RJJ Transcriptional regulator BZ16_4007 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BZ16_4008 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BZ16_4009 ENOG4108JQ7 (ABC) transporter BZ16_4010 ENOG4105C3U ABC transporter BZ16_4011 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ16_4012 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ16_4014 ENOG4105XEP YhcH YjgK YiaL family protein BZ16_4016 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) BZ16_4017 ENOG4108MJ3 acetyltransferase BZ16_4019 ENOG4105MYG DNA polymerase iii, chi subunit BZ16_4021 ENOG4108M8S permease YjgP YjgQ family protein BZ16_4022 ENOG4108K5H permease YjgP YjgQ family protein BZ16_4027 ENOG4105DZR Type I site-specific deoxyribonuclease BZ16_4028 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BZ16_4029 ENOG4105RI1 glycoprotein receptor BZ16_4036 ENOG4105DKT Transcriptional regulator BZ16_4038 ENOG4105DKP glycosyl transferase, family 9 BZ16_4040 ENOG4105C9B Cysteine desulfurase BZ16_4046 ENOG410624X efflux transporter, rnd family, mfp subunit BZ16_4047 ENOG4105BZS acriflavin resistance protein BZ16_4050 ENOG4105BZU Histidine kinase BZ16_4051 ENOG4105YBH Protein of unknown function (DUF1435) BZ16_4056 ENOG4108WPU DNA polymerase III subunit psi BZ16_4057 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BZ16_4059 ENOG4105K3G Periplasmic Protein BZ16_4061 ENOG4108NRW Phospholipase, patatin family BZ16_4062 ENOG4105EYA deoxyribonuclease BZ16_4063 ENOG4105D9N nucleoside BZ16_4064 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ16_4068 ENOG41062Z9 Membrane BZ16_4069 ENOG4105EAC phosphoserine phosphatase BZ16_407 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase BZ16_4070 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BZ16_4071 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase BZ16_4073 ENOG4105C5H ABC transporter BZ16_4074 ENOG41090EK ompa motb domain protein BZ16_4075 ENOG4108KHX Diguanylate cyclase BZ16_4078 ENOG4107SC1 transglycosylase BZ16_408 ENOG4108HPI phosphatidate Cytidylyltransferase BZ16_4080 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) BZ16_4081 ENOG4105UEI Transcriptional Regulator AraC Family BZ16_4084 ENOG4108RH0 Crea protein BZ16_4085 ENOG41065U4 response regulator BZ16_4093 ENOG4108RIR Molybdenum cofactor biosynthesis protein BZ16_4096 ENOG4106HK8 GPR1 FUN34 yaaH family protein BZ16_410 ENOG4105E8V Alpha Beta Hydrolase Fold protein BZ16_4100 ENOG41063Z6 transcriptional regulator, lysR family BZ16_4102 ENOG4105DTN riboflavin biosynthesis protein ribF BZ16_4105 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BZ16_4109 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BZ16_411 ENOG41077RS Phosphatase BZ16_4110 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BZ16_4111 ENOG4108NIW Leucine export protein LeuE BZ16_4112 ENOG4105DWK Membrane BZ16_4114 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BZ16_4120 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BZ16_4123 ENOG4105D3G Pseudouridine synthase BZ16_4132 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ16_4133 ENOG4105CS6 Rhs element vgr protein BZ16_414 ENOG4105EQ2 LysR family Transcriptional regulator BZ16_4146 ENOG4105EZN Cobyrinic acid ac-diamide synthase BZ16_4147 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB BZ16_415 ENOG4107SET aldo keto reductase BZ16_4156 ENOG4105CMM transposase BZ16_4160 ENOG4108C33 Resolvase BZ16_4162 ENOG4105D13 transposase BZ16_4171 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) BZ16_4173 ENOG4106CQM replication BZ16_418 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ16_4182 ENOG4105CMM transposase BZ16_421 ENOG4105FE9 pseudouridine synthase BZ16_422 ENOG4105EZE Cupin 4 family protein BZ16_427 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ16_43 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BZ16_432 ENOG4105HVQ Regulatory factor of maltose metabolism BZ16_433 ENOG4108JQB penicillin-binding protein 1C BZ16_434 ENOG4105DN3 alpha-2-macroglobulin domain protein BZ16_437 ENOG4105C26 Dehydrogenase BZ16_438 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BZ16_44 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BZ16_440 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ16_441 ENOG4105C2J ABC transporter BZ16_442 ENOG4105CNN ABC, transporter BZ16_443 ENOG4105CK5 oxidoreductase BZ16_444 ENOG4105EDK PfkB domain protein BZ16_446 ENOG4105DH8 myo-inositol catabolism BZ16_448 ENOG4108JJ7 ABC transporter BZ16_45 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BZ16_452 ENOG4108N8T regulatoR BZ16_454 ENOG4105VEQ Cold shock protein BZ16_456 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) BZ16_460 ENOG4105DZ1 carboxypeptidase BZ16_461 ENOG4105K6T rare lipoprotein A BZ16_462 ENOG4105CNI cell division protein FtsW BZ16_463 ENOG4105CJN penicillin-binding protein BZ16_465 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BZ16_467 ENOG4105DJF DNA polymerase III, delta' subunit BZ16_470 ENOG4107PAI alpha helical protein BZ16_471 ENOG4105CDA abc transporter atp-binding protein BZ16_472 ENOG4105DRP amino acid AbC transporter BZ16_473 ENOG4105EAD ABC transporter BZ16_474 ENOG4107RP9 extracellular solute-binding protein, family 3 BZ16_475 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BZ16_476 ENOG4108JU5 Magnesium and cobalt efflux protein BZ16_478 ENOG4105C9A Phoh family BZ16_480 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ16_487 ENOG4105CAQ asparagine synthetase BZ16_488 ENOG4105D4U had-superfamily hydrolase, subfamily iia BZ16_489 ENOG4105E2R ROK family BZ16_490 ENOG4105CE4 GlcNAc 6-P deacetylase BZ16_492 ENOG4105CI1 PTS System BZ16_496 ENOG41090R7 Ferric uptake BZ16_497 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) BZ16_498 ENOG4105NNH LexA regulated protein BZ16_50 ENOG4105M6F mutator MutT protein BZ16_500 ENOG4105EV9 Alpha Beta Hydrolase BZ16_503 ENOG4105DFP Integrase BZ16_505 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures BZ16_508 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles BZ16_509 ENOG4108XS9 dna repair protein BZ16_51 ENOG4108RS6 transposase BZ16_510 ENOG4106H6R UPF0380 protein BZ16_513 ENOG4108MXD gtp-binding protein BZ16_514 ENOG4108P8R BZ16_521 ENOG4105DFP Integrase BZ16_523 ENOG4108Z1B Cyclase dehydrase BZ16_525 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ16_526 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BZ16_529 ENOG4105BZN citrate synthase BZ16_530 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BZ16_531 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BZ16_533 ENOG4105E33 succinate dehydrogenase BZ16_534 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BZ16_535 ENOG4105C7S Dehydrogenase BZ16_537 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BZ16_538 ENOG4105C4M (Ubiquinol oxidase) subunit I BZ16_539 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BZ16_54 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BZ16_541 ENOG4105KJB cyd operon protein YbgE BZ16_542 ENOG4107YD3 Thioesterase BZ16_543 ENOG4105E02 MotA TolQ exbB proton channel BZ16_544 ENOG4105M8F Biopolymer transport protein exbD tolR BZ16_545 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ16_545 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ16_547 ENOG4105KCK Peptidoglycan-associated lipoprotein BZ16_548 ENOG4105UFD tol-pal system protein YbgF BZ16_555 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BZ16_556 ENOG4105PGM cation diffusion facilitator family transporter BZ16_558 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ16_561 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BZ16_563 ENOG4105F0Z galactose-1-phosphate uridylyltransferase BZ16_564 ENOG4105CMR udp-glucose 4-epimerase BZ16_567 ENOG4105DKW ABC transporter BZ16_568 ENOG4105F4R Transcriptional regulator mode BZ16_569 ENOG410680R Protein of unknown function (DUF2592) BZ16_57 ENOG4105D7Q type ii secretion system BZ16_570 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BZ16_571 ENOG4105E0C molybdate abc transporter BZ16_573 ENOG4108K4B hydrolase BZ16_578 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BZ16_579 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ16_58 ENOG4107QHF type ii secretion system protein e BZ16_580 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BZ16_582 ENOG4105VYA Uncharacterized conserved protein (DUF2132) BZ16_583 ENOG4105CHW UPF0052 protein BZ16_585 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BZ16_587 ENOG4105M00 molybdopterin converting factor, subunit 1 BZ16_588 ENOG4108ZAF Molybdopterin BZ16_589 ENOG4105HFZ Membrane BZ16_59 ENOG4108ZUW Major pilin subunit BZ16_593 ENOG4105C94 Transporter BZ16_594 ENOG4105CN8 Transcriptional regulator BZ16_596 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BZ16_597 ENOG4105EAA nucleoside BZ16_599 ENOG4105BZU Histidine kinase BZ16_60 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BZ16_602 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ16_604 ENOG4107QWP ABC-2 type transporter BZ16_605 ENOG4107QWP ABC-2 type transporter BZ16_606 ENOG4105CJ1 ABC, transporter BZ16_608 ENOG4107MVR Transcriptional regulator BZ16_609 ENOG4105C1J atp-dependent rna helicase BZ16_61 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ16_610 ENOG4105EQR Transposase IS116 IS110 IS902 BZ16_615 ENOG4105EQR Transposase IS116 IS110 IS902 BZ16_616 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BZ16_618 ENOG41061WM D-Alanyl-D-Alanine BZ16_619 ENOG4105CXG d-lactate dehydrogenase BZ16_62 ENOG4106A72 regulatory protein AmpE BZ16_621 ENOG4105N1F Hnh endonuclease BZ16_623 ENOG4105Y3U Transglycosylase-associated protein BZ16_625 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein BZ16_628 ENOG4108W15 Protein of unknown function (DUF1456) BZ16_63 ENOG4105C85 amino acid BZ16_630 ENOG4105C32 Amino acid ABC transporter (Permease) BZ16_631 ENOG4105CNN ABC, transporter BZ16_632 ENOG4108JJB ABC transporter BZ16_633 ENOG4108IV0 ABC, transporter BZ16_636 ENOG4105KHC sulfurtransferase BZ16_637 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BZ16_638 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component BZ16_639 ENOG4108IJ8 ABC transporter BZ16_64 ENOG41073TP transcriptional regulator BZ16_640 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component BZ16_641 ENOG4105D5Q Arginine ornithine antiporter BZ16_642 ENOG4105CXN decarboxylase BZ16_644 ENOG4105FDR Membrane BZ16_646 ENOG4105DVT helicase BZ16_647 ENOG4105CH6 catalase BZ16_648 ENOG4108UII YfaZ family BZ16_649 ENOG4105E0U tyrosine-specific transport protein BZ16_65 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BZ16_652 ENOG4105XPH Ferredoxin BZ16_653 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ16_654 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ16_656 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ16_657 ENOG4105BZU Histidine kinase BZ16_658 ENOG41068CG regulatoR BZ16_659 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC BZ16_66 ENOG4107QSN dihydrolipoamide acetyltransferase BZ16_660 ENOG4106UW1 Major Facilitator superfamily BZ16_662 ENOG4105FCK Membrane BZ16_665 ENOG4107R6D beta-lactam binding protein AmpH BZ16_666 ENOG4105CT4 transporter BZ16_668 ENOG4105C8Q Methyl-accepting chemotaxis BZ16_67 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ16_670 ENOG4105Y50 Virulence Protein BZ16_672 ENOG4105HRS Antitermination protein BZ16_673 ENOG4105G63 Type III effector Hrp-dependent BZ16_675 ENOG4105MVE transcriptional regulator BZ16_676 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BZ16_68 ENOG4107QIJ Aconitate hydratase 2 BZ16_680 ENOG4105TKZ Tail Sheath BZ16_688 ENOG4108T86 baseplate J family protein BZ16_691 ENOG4108Q3X Transcriptional regulator BZ16_693 ENOG4105CS2 ec 3.2.1.21 BZ16_698 ENOG4105GMB type VI secretion system effector, hcp1 family BZ16_70 ENOG4105RPH Inner membrane protein YddG BZ16_701 ENOG4105E68 Sulfatase BZ16_702 ENOG4105PAN UPF0352 protein BZ16_705 ENOG4105CFI type iii restriction protein res subunit BZ16_706 ENOG4105I08 Pseudouridine synthase BZ16_707 ENOG4105C2C drug resistance transporter, Bcr CflA BZ16_708 ENOG4105HG6 BZ16_709 ENOG4108JQ5 ABC transporter BZ16_710 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BZ16_711 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BZ16_712 ENOG4105E43 Extracellular solute-binding protein, family 5 BZ16_713 ENOG4105CXC rtn protein BZ16_714 ENOG4107TT5 NLP P60 protein BZ16_715 ENOG41076MN Phosphoesterase, PA-phosphatase related BZ16_716 ENOG4105CKI cobalamin synthesis protein BZ16_718 ENOG4107YCY Transcriptional regulator BZ16_719 ENOG4105DEI Mannitol dehydrogenase BZ16_723 ENOG4105KRS Proteinase inhibitor BZ16_724 ENOG4105CHR reductase BZ16_727 ENOG4105C26 Dehydrogenase BZ16_73 ENOG4108ZRK uncharacterized protein yacC BZ16_732 ENOG4105C2J ABC transporter BZ16_733 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BZ16_735 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein BZ16_736 ENOG4105DE4 1-phosphofructokinase BZ16_737 ENOG4105DM4 PTS System BZ16_738 ENOG4108SGD regulatory protein BZ16_74 ENOG4105E3B Multicopper oxidase BZ16_741 ENOG4108UIF Chaperone BZ16_742 ENOG4108D1K outer membrane usher protein BZ16_744 ENOG4105HMI Membrane BZ16_745 ENOG4105DUM transcriptional regulator, lysR family BZ16_747 ENOG4108IQI permease BZ16_749 ENOG4105EHG Permease protein BZ16_75 ENOG4108UGV hypoxanthine phosphoribosyltransferase BZ16_751 ENOG4105D05 Receptor BZ16_752 ENOG4108TGY Glutathione S-transferase BZ16_755 ENOG4105D01 (LipO)protein BZ16_757 ENOG4108UMI ABC transporter, permease BZ16_758 ENOG4105DZ1 carboxypeptidase BZ16_759 ENOG4105C44 Serine transporter BZ16_76 ENOG41077A9 carbonic anhydrase BZ16_760 ENOG4107FB0 transcriptional regulator DeoR family BZ16_761 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ16_762 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BZ16_764 ENOG4105D0C transport protein BZ16_765 ENOG41090BQ Glutaredoxin BZ16_766 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress BZ16_767 ENOG4108RMJ sensory transduction regulator BZ16_768 ENOG4107RUE extracellular solute-binding protein family 1 BZ16_769 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ16_77 ENOG4105DA5 (ABC) transporter BZ16_770 ENOG4105F38 ABC transporter, permease BZ16_771 ENOG4105D38 putrescine abc transporter BZ16_772 ENOG4105RBQ inner membrane protein ybjO BZ16_774 ENOG4106TNF Periplasmic binding protein BZ16_777 ENOG4108I9K permease protein BZ16_778 ENOG4105E0A ABC, transporter BZ16_779 ENOG410642S Nicotianamine synthase protein BZ16_78 ENOG4105E3A (ABC) transporter BZ16_780 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) BZ16_781 ENOG4108I0N Transporter, RarD family, DMT superfamily protein BZ16_782 ENOG4105DMR ABC, transporter BZ16_783 ENOG4105GBT ABC transporter BZ16_784 ENOG4106PMH Extracellular solute-binding protein family 3 BZ16_785 ENOG4105E5Z arginine transporter ATP-binding subunit BZ16_786 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) BZ16_787 ENOG41064MM (LipO)protein BZ16_788 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ16_789 ENOG4105CGD Nad-dependent epimerase dehydratase BZ16_79 ENOG4107BJW polysaccharide deacetylase BZ16_790 ENOG4105C5W Aldolase BZ16_791 ENOG4105C7K acetolactate synthase BZ16_792 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ16_794 ENOG4105DWU Membrane BZ16_795 ENOG4105CPB ATP-dependent endonuclease of the OLD family BZ16_796 ENOG4108MJ5 VirK protein BZ16_797 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ16_799 ENOG4105VEQ Cold shock protein BZ16_801 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ16_802 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BZ16_804 ENOG4108JJ8 (ABC) transporter BZ16_805 ENOG4108JJ9 ABC, transporter BZ16_806 ENOG4105C3M thioredoxin reductase BZ16_807 ENOG4105EW9 transcriptional regulator AsnC family BZ16_808 ENOG4105CNU cell division protein FtsK BZ16_811 ENOG4105D1H recombination factor protein RarA BZ16_813 ENOG4108ISG Major Facilitator BZ16_814 ENOG4105F1A Pyruvate formate-lyase BZ16_816 ENOG4105C6N Formate acetyltransferase BZ16_817 ENOG4105TMB Formate nitrite transporter BZ16_818 ENOG4105DDY UPF0142 protein ycaO BZ16_819 ENOG4105HDK L-asparaginase BZ16_825 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BZ16_828 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BZ16_83 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BZ16_831 ENOG4105E32 cytoplasmic protein BZ16_832 ENOG4105VEQ Cold shock protein BZ16_833 ENOG4105W49 UPF0434 protein BZ16_835 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups BZ16_836 ENOG4106371 Methyltransferase BZ16_837 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) BZ16_838 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) BZ16_84 ENOG4105DJ0 Poly(A) Polymerase BZ16_840 ENOG4105DIT ErfK YbiS YcfS YnhG family protein BZ16_841 ENOG4105EAQ (twin-arginine translocation) pathway signal BZ16_842 ENOG4105C5X domain protein BZ16_843 ENOG4105CGF Aromatic amino acid aminotransferase BZ16_847 ENOG4105CD8 aminopeptidase N BZ16_850 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) BZ16_851 ENOG4105QVC MOSC domain-containing protein BZ16_853 ENOG4105C5H ABC transporter BZ16_854 ENOG4105F1S paraquat-inducible protein a BZ16_855 ENOG4105DY2 Paraquat-inducible protein b BZ16_856 ENOG4108Q2G (LipO)protein BZ16_857 ENOG4108RS6 transposase BZ16_858 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ16_86 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BZ16_861 ENOG4105DAN ATP-dependent protease BZ16_863 ENOG4105UYK outer membrane protein a BZ16_865 ENOG4108RZ1 DNA transformation protein BZ16_866 ENOG4105EM2 membrane BZ16_867 ENOG410901E Membrane BZ16_868 ENOG41088T4 Helicase IV BZ16_870 ENOG4108Q67 UPF0319 protein BZ16_871 ENOG4105K4P CoA-binding domain protein BZ16_875 ENOG4108Z0T Part of a sulfur-relay system (By similarity) BZ16_878 ENOG4108BUD transposase BZ16_88 ENOG4107XID 2'-5' rna ligase BZ16_884 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BZ16_885 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ16_886 ENOG4105CHR reductase BZ16_887 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BZ16_889 ENOG4108KQ6 Enoyl-CoA hydratase BZ16_89 ENOG4105CQ7 ATP-dependent helicase BZ16_890 ENOG4105CHR reductase BZ16_892 ENOG41062T2 Acyl carrier protein BZ16_893 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ16_899 ENOG4105CDV Ompa motb domain protein BZ16_90 ENOG4105BZ4 penicillin-binding protein BZ16_901 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ16_91 ENOG4105E0A ABC, transporter BZ16_92 ENOG4105J76 Periplasmic binding protein BZ16_920 ENOG4105C5H ABC transporter BZ16_922 ENOG4105D06 uba thif-type nad fad binding protein BZ16_923 ENOG4105CVM Molybdenum cofactor synthesis domain protein BZ16_926 ENOG4105C19 ABC transporter BZ16_927 ENOG4105ENT Efflux transporter rnd family, mfp subunit BZ16_93 ENOG4105S6R Iron-hydroxamate transporter permease subunit BZ16_932 ENOG4105EGI Transcriptional regulator BZ16_933 ENOG4105CBP Major Facilitator BZ16_935 ENOG4105DHF Membrane BZ16_938 ENOG4108HWV )-transporter BZ16_939 ENOG4107GZ4 SanA protein BZ16_942 ENOG41067MG lrgb family BZ16_944 ENOG4105E5W Transporter BZ16_949 ENOG4105D1F ATP-binding protein BZ16_952 ENOG4108GAE asmA family BZ16_953 ENOG4105EE5 Membrane protein terC BZ16_954 ENOG4108819 ferric iron reductase BZ16_955 ENOG4105DY8 decarboxylase BZ16_956 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ16_958 ENOG4105DUU IucA IucC family protein BZ16_959 ENOG4105E0A ABC, transporter BZ16_960 ENOG4105TVJ transport system, permease BZ16_961 ENOG4105DQ5 transport system permease protein BZ16_962 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BZ16_963 ENOG4105CNM Receptor BZ16_964 ENOG4105DUU IucA IucC family protein BZ16_965 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ16_966 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ16_967 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BZ16_968 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BZ16_97 ENOG4105EN6 Membrane BZ16_971 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BZ16_976 ENOG4108535 NAD dependent epimerase/dehydratase family BZ16_979 ENOG4105CNN ABC, transporter BZ16_980 ENOG4105C2J ABC transporter BZ16_981 ENOG4107SCQ Iron-containing alcohol dehydrogenase BZ16_983 ENOG4105CUB amino acid BZ16_984 ENOG4105CJB Exodeoxyribonuclease I BZ16_987 ENOG4105TNG K13735 adhesin invasin BZ16_988 ENOG4105CSP Major Facilitator Superfamily BZ16_989 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BZ16_990 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BZ16_992 ENOG4105DIA mandelate racemase muconate lactonizing BZ16_996 ENOG4105UQX Mate efflux family protein