locus-tag	class	description
BZ16_10	COG0417	DNA replication proofreading
BZ16_1000	COG3122	Protein conserved in bacteria
BZ16_101	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ16_1010	COG4771	TonB-dependent receptor
BZ16_1011	COG1021	2,3-dihydroxybenzoate-AMP ligase
BZ16_1015	COG3433	isochorismatase activity
BZ16_1015	COG2226	methyltransferase
BZ16_1015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ16_1018	COG1132	(ABC) transporter
BZ16_1019	COG2814	Major facilitator Superfamily
BZ16_102	COG3437	response regulator, receiver
BZ16_102	COG2205	protein histidine kinase activity
BZ16_102	COG4999	Histidine kinase
BZ16_102	COG3850	Histidine kinase
BZ16_1020	COG1169	isochorismate synthase
BZ16_1021	COG0582	viral genome integration into host DNA
BZ16_1022	COG0582	viral genome integration into host DNA
BZ16_1027	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BZ16_103	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BZ16_1032	COG2223	nitrite transmembrane transporter activity
BZ16_1038	COG1132	(ABC) transporter
BZ16_104	COG3956	TIGRFAM MazG family protein
BZ16_1040	COG2207	Transcriptional regulator
BZ16_1047	COG1113	amino acid transport
BZ16_1050	COG1278	Cold shock
BZ16_1052	COG2226	methyltransferase
BZ16_1054	COG3447	MASE1 domain protein
BZ16_1054	COG5001	Diguanylate cyclase
BZ16_1054	COG5002	protein histidine kinase activity
BZ16_1058	COG3716	PTS system mannose fructose sorbose family IID component
BZ16_1059	COG3715	PTS system
BZ16_1060	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ16_1060	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ16_1061	COG1253	flavin adenine dinucleotide binding
BZ16_1062	COG1846	Transcriptional regulator
BZ16_1065	COG1012	belongs to the aldehyde dehydrogenase family
BZ16_1066	COG3384	dioxygenase
BZ16_1068	COG3971	2-oxopent-4-enoate hydratase activity
BZ16_1071	COG2368	4-hydroxyphenylacetate
BZ16_1072	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BZ16_1073	COG1760	l-serine dehydratase
BZ16_1078	COG0513	Belongs to the DEAD box helicase family
BZ16_1079	COG3141	response to X-ray
BZ16_108	COG0602	queuosine metabolic process
BZ16_1082	COG1770	oligopeptidase
BZ16_1085	COG1528	Iron-storage protein
BZ16_1086	COG2372	response to copper ion
BZ16_109	COG0720	synthase
BZ16_1090	COG3328	transposase activity
BZ16_1093	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ16_1094	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ16_1097	COG3418	PFAM FlgN family protein
BZ16_1098	COG2747	anti-sigma28 factor FlgM
BZ16_11	COG0586	Pfam SNARE associated Golgi protein
BZ16_1100	COG1815	bacterial-type flagellum-dependent cell motility
BZ16_1101	COG1558	bacterial-type flagellum-dependent cell motility
BZ16_1102	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BZ16_1103	COG1749	Flagellar hook protein flgE
BZ16_1105	COG4786	Flagellar basal body rod
BZ16_1109	COG1256	bacterial-type flagellum assembly
BZ16_1111	COG2390	Transcriptional regulator
BZ16_1112	COG3347	Dehydrogenase
BZ16_1112	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_1114	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_1116	COG1129	ABC transporter
BZ16_1117	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_1118	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ16_1122	COG1987	bacterial-type flagellum assembly
BZ16_1127	COG1580	Controls the rotational direction of flagella during chemotaxis
BZ16_1129	COG2882	bacterial-type flagellum organization
BZ16_1130	COG1157	protein secretion by the type III secretion system
BZ16_1132	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BZ16_1134	COG1677	Flagellar hook-basal body complex protein FliE
BZ16_1137	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BZ16_1138	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BZ16_1144	COG1191	sigma factor activity
BZ16_1152	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZ16_1152	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZ16_1152	COG0506	proline dehydrogenase activity
BZ16_1160	COG1113	amino acid transport
BZ16_1164	COG3136	membrane protein required for alginate biosynthesis
BZ16_1166	COG2197	response regulator
BZ16_118	COG0529	Catalyzes the synthesis of activated sulfate
BZ16_1199	COG4695	Portal protein
BZ16_1207	COG5002	protein histidine kinase activity
BZ16_1207	COG2176	DNA-directed DNA polymerase activity
BZ16_1221	COG4974	Belongs to the 'phage' integrase family
BZ16_1239	COG2963	transposase activity
BZ16_1251	COG3328	transposase activity
BZ16_1252	COG3328	transposase activity
BZ16_1259	COG0673	inositol 2-dehydrogenase activity
BZ16_126	COG4942	peptidase
BZ16_126	COG1388	LysM domain
BZ16_1261	COG1175	transmembrane transport
BZ16_1262	COG0395	ABC-type sugar transport system, permease component
BZ16_1265	COG3121	Chaperone
BZ16_1267	COG3188	usher protein
BZ16_127	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZ16_1270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ16_1270	COG2205	protein histidine kinase activity
BZ16_1272	COG0427	acetyl-CoA hydrolase
BZ16_1273	COG2030	dehydratase
BZ16_1281	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ16_1282	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZ16_1284	COG1349	DNA-binding transcription factor activity
BZ16_1285	COG2066	Belongs to the glutaminase family
BZ16_1287	COG0672	)-iron permease
BZ16_129	COG0698	ribose 5-phosphate isomerase
BZ16_1290	COG0577	efflux transmembrane transporter activity
BZ16_1290	COG1136	(ABC) transporter
BZ16_1292	COG0577	efflux transmembrane transporter activity
BZ16_1292	COG1136	(ABC) transporter
BZ16_1296	COG0006	proline dipeptidase activity
BZ16_1297	COG0457	Tetratricopeptide repeat
BZ16_1298	COG1649	PFAM Uncharacterised BCR, COG1649
BZ16_1298	COG0726	polysaccharide deacetylase
BZ16_1299	COG1215	transferase activity, transferring glycosyl groups
BZ16_13	COG1178	ABC-type Fe3 transport system permease component
BZ16_130	COG1063	alcohol dehydrogenase
BZ16_1300	COG3658	cytochrome
BZ16_1303	COG1702	phosphate starvation-inducible protein PhoH
BZ16_1304	COG0387	Pfam Sodium calcium exchanger
BZ16_1305	COG3850	Histidine kinase
BZ16_1306	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZ16_131	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_1317	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BZ16_132	COG2376	Dihydroxyacetone kinase
BZ16_1321	COG0402	S-adenosylhomocysteine deaminase activity
BZ16_1324	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BZ16_1325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ16_1338	COG0500	methyltransferase
BZ16_1347	COG5002	protein histidine kinase activity
BZ16_135	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BZ16_1353	COG0012	GTP binding
BZ16_1356	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZ16_1361	COG2890	protein-(glutamine-N5) methyltransferase activity
BZ16_1362	COG3094	Invasion gene expression up-regulator, SirB
BZ16_1363	COG2912	Transglutaminase-like superfamily
BZ16_1365	COG0659	secondary active sulfate transmembrane transporter activity
BZ16_1369	COG3833	ABC-type maltose transport systems, permease component
BZ16_1370	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ16_1372	COG0584	glycerophosphoryl diester phosphodiesterase
BZ16_1373	COG1940	carbohydrate kinase activity
BZ16_1376	COG3381	protein complex oligomerization
BZ16_1379	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ16_1382	COG0728	peptidoglycan biosynthetic process
BZ16_1387	COG3102	Protein conserved in bacteria
BZ16_139	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ16_1391	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BZ16_1392	COG1801	Protein of unknown function DUF72
BZ16_1394	COG0494	nUDIX hydrolase
BZ16_1399	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ16_14	COG4143	(ABC) transporter
BZ16_140	COG1858	cytochrome C peroxidase
BZ16_1401	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BZ16_1402	COG0739	heme binding
BZ16_1403	COG1560	Kdo2-lipid A biosynthetic process
BZ16_1404	COG0469	pyruvate kinase activity
BZ16_1405	COG1737	Transcriptional regulator
BZ16_1406	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BZ16_1408	COG0800	Aldolase
BZ16_1411	COG0251	oxidation-reduction process
BZ16_1412	COG1199	ATP-dependent helicase activity
BZ16_1414	COG3065	identical protein binding
BZ16_1415	COG0318	PFAM AMP-dependent synthetase and ligase
BZ16_1416	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BZ16_1417	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BZ16_1418	COG2894	cell division
BZ16_1421	COG2951	lytic endotransglycosylase activity
BZ16_1422	COG0179	Fumarylacetoacetate (FAA) hydrolase
BZ16_1425	COG1104	cysteine desulfurase activity
BZ16_143	COG4771	TonB-dependent receptor
BZ16_1431	COG2719	SpoVR family
BZ16_1433	COG2814	Major facilitator Superfamily
BZ16_1435	COG0583	DNA-binding transcription factor activity
BZ16_1438	COG2766	serine protein kinase
BZ16_1439	COG3713	MltA-interacting MipA family protein
BZ16_1443	COG3139	Protein of unknown function (DUF1315)
BZ16_1444	COG1335	isochorismatase
BZ16_1445	COG0252	asparaginase activity
BZ16_1446	COG0616	signal peptide processing
BZ16_1447	COG0778	Nitroreductase
BZ16_1449	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BZ16_145	COG0024	Methionine aminopeptidase
BZ16_1451	COG0494	nUDIX hydrolase
BZ16_1452	COG0708	Exodeoxyribonuclease III
BZ16_1453	COG0583	DNA-binding transcription factor activity
BZ16_1456	COG0788	formyltetrahydrofolate deformylase activity
BZ16_1458	COG0745	RESPONSE REGULATOR receiver
BZ16_1461	COG1435	thymidine kinase activity
BZ16_1462	COG1454	alcohol dehydrogenase
BZ16_1462	COG1012	belongs to the aldehyde dehydrogenase family
BZ16_1463	COG2095	MarC family integral membrane protein
BZ16_1465	COG0601	transmembrane transport
BZ16_1466	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ16_1467	COG0444	Belongs to the ABC transporter superfamily
BZ16_1468	COG4608	Belongs to the ABC transporter superfamily
BZ16_147	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BZ16_147	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BZ16_1475	COG2350	Protein conserved in bacteria
BZ16_1477	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BZ16_1478	COG1607	acyl-coa hydrolase
BZ16_148	COG1070	Carbohydrate kinase
BZ16_1482	COG3047	cAMP biosynthetic process
BZ16_1486	COG0135	phosphoribosylanthranilate isomerase activity
BZ16_1486	COG0134	indole-3-glycerol-phosphate synthase activity
BZ16_1488	COG0512	Glutamine amidotransferase of anthranilate synthase
BZ16_149	COG3623	hexulose-6-phosphate isomerase
BZ16_1491	COG0009	L-threonylcarbamoyladenylate synthase
BZ16_1492	COG1187	pseudouridine synthase activity
BZ16_1494	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_1495	COG0616	signal peptide processing
BZ16_1498	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BZ16_1499	COG0583	DNA-binding transcription factor activity
BZ16_150	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_1501	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BZ16_1502	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZ16_1503	COG0671	phosphoesterase, PA-phosphatase related
BZ16_1504	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BZ16_1505	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BZ16_1508	COG0023	Translation Initiation Factor
BZ16_151	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_1512	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZ16_1513	COG2879	small protein
BZ16_1514	COG1966	Carbon starvation protein
BZ16_1516	COG2271	Major facilitator Superfamily
BZ16_1517	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ16_1518	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BZ16_152	COG1129	ABC transporter
BZ16_1520	COG4659	FMN binding
BZ16_1522	COG3708	Transcriptional regulator
BZ16_1522	COG2207	Transcriptional regulator
BZ16_1529	COG2274	protein secretion by the type I secretion system
BZ16_1533	COG1879	ABC-type sugar transport system periplasmic component
BZ16_1535	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_1537	COG0673	inositol 2-dehydrogenase activity
BZ16_1538	COG0385	Bile acid
BZ16_154	COG1349	DNA-binding transcription factor activity
BZ16_1542	COG2190	(PTS) system
BZ16_1542	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ16_1542	COG1263	PTS System
BZ16_1544	COG5339	Protein conserved in bacteria
BZ16_1545	COG1482	cell wall glycoprotein biosynthetic process
BZ16_1546	COG0114	fumarate hydratase activity
BZ16_1548	COG2814	Major facilitator Superfamily
BZ16_1549	COG0583	DNA-binding transcription factor activity
BZ16_155	COG0235	Class ii aldolase
BZ16_1550	COG1940	carbohydrate kinase activity
BZ16_1552	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BZ16_1556	COG4221	oxidoreductase activity
BZ16_1557	COG3284	Transcriptional regulator
BZ16_1559	COG4221	oxidoreductase activity
BZ16_156	COG0243	molybdopterin cofactor binding
BZ16_1560	COG3284	Transcriptional regulator
BZ16_1561	COG1012	belongs to the aldehyde dehydrogenase family
BZ16_1564	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BZ16_1565	COG1757	Na H antiporter
BZ16_1566	COG1609	Transcriptional regulator
BZ16_1568	COG1879	ABC-type sugar transport system periplasmic component
BZ16_1569	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_157	COG0437	4 iron, 4 sulfur cluster binding
BZ16_1570	COG1129	ABC transporter
BZ16_1572	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZ16_1573	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ16_1575	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BZ16_158	COG3302	dmso reductase anchor subunit
BZ16_1580	COG0028	Belongs to the TPP enzyme family
BZ16_1581	COG0440	acetolactate synthase activity
BZ16_1582	COG1011	Hydrolase
BZ16_1585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZ16_1586	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZ16_1587	COG0589	response to stress
BZ16_1588	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BZ16_1589	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BZ16_159	COG3381	protein complex oligomerization
BZ16_1591	COG0531	amino acid
BZ16_1593	COG0745	RESPONSE REGULATOR receiver
BZ16_1594	COG2205	protein histidine kinase activity
BZ16_1595	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BZ16_1598	COG3038	cytochrome b561
BZ16_160	COG3038	cytochrome b561
BZ16_1600	COG3591	Belongs to the peptidase S1B family
BZ16_1603	COG1643	Atp-dependent helicase
BZ16_1605	COG2390	Transcriptional regulator
BZ16_1606	COG0246	Mannitol dehydrogenase
BZ16_1607	COG3784	Protein of unknown function (DUF1318)
BZ16_1609	COG2911	Protein conserved in bacteria
BZ16_161	COG3783	Cytochrome b(562)
BZ16_1610	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ16_1611	COG3187	Heat shock protein
BZ16_1612	COG3042	response to heat
BZ16_1613	COG1285	pathogenesis
BZ16_1615	COG1013	pyruvate-flavodoxin oxidoreductase activity
BZ16_1615	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BZ16_1615	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ16_1615	COG0674	pyruvate-flavodoxin oxidoreductase activity
BZ16_1618	COG0657	acetylesterase activity
BZ16_1618	COG2755	lipolytic protein G-D-S-L family
BZ16_1621	COG4166	transmembrane transport
BZ16_1622	COG2866	Carboxypeptidase
BZ16_1623	COG4948	Mandelate Racemase Muconate Lactonizing
BZ16_1624	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BZ16_1629	COG3106	COG3106 Predicted ATPase
BZ16_1631	COG1983	PspC domain protein
BZ16_1633	COG1842	Phage shock protein A
BZ16_1634	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BZ16_1635	COG4166	transmembrane transport
BZ16_1636	COG4168	peptide transport system, permease
BZ16_1637	COG4171	peptide transport system, permease
BZ16_1639	COG4172	Belongs to the ABC transporter superfamily
BZ16_1640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ16_1640	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ16_1642	COG3104	oligopeptide transport
BZ16_1645	COG0625	glutathione transferase activity
BZ16_1649	COG4989	oxidoreductase activity
BZ16_165	COG1129	ABC transporter
BZ16_1650	COG3313	Fe-S protein
BZ16_1651	COG2194	sulfuric ester hydrolase activity
BZ16_1652	COG1309	transcriptional regulator
BZ16_1653	COG1902	pentaerythritol trinitrate reductase activity
BZ16_1655	COG0346	lactoylglutathione lyase activity
BZ16_1657	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BZ16_1659	COG0791	NLP P60 protein
BZ16_166	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_1660	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZ16_1663	COG0583	DNA-binding transcription factor activity
BZ16_1664	COG2814	Major facilitator Superfamily
BZ16_1665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BZ16_1666	COG0307	riboflavin synthase, alpha
BZ16_167	COG3959	Transketolase, thiamine diphosphate binding domain
BZ16_1672	COG4238	major outer membrane lipoprotein
BZ16_1673	COG1376	ErfK ybiS ycfS ynhG family protein
BZ16_1673	COG1388	LysM domain
BZ16_1676	COG0719	Fe-S assembly protein
BZ16_1677	COG0396	ATPase activity
BZ16_1678	COG0719	Fe-S assembly protein
BZ16_1679	COG0316	Belongs to the HesB IscA family
BZ16_168	COG3958	Transketolase
BZ16_1680	COG2050	protein possibly involved in aromatic compounds catabolism
BZ16_1681	COG0247	lactate metabolic process
BZ16_1681	COG0277	FAD linked oxidase domain protein
BZ16_1682	COG0628	permease
BZ16_1683	COG0574	Belongs to the PEP-utilizing enzyme family
BZ16_1683	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZ16_1688	COG0791	NLP P60 protein
BZ16_169	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BZ16_1696	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BZ16_1697	COG0386	Belongs to the glutathione peroxidase family
BZ16_1700	COG0776	regulation of translation
BZ16_1707	COG4249	Peptidase C14 caspase catalytic subunit p20
BZ16_1711	COG0803	Belongs to the bacterial solute-binding protein 9 family
BZ16_1712	COG1121	(ABC) transporter
BZ16_1713	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ16_1714	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ16_1717	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ16_1718	COG1917	Cupin 2, conserved barrel domain protein
BZ16_1720	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_1722	COG1175	transmembrane transport
BZ16_1723	COG0395	ABC-type sugar transport system, permease component
BZ16_1724	COG3842	ATPase activity
BZ16_1725	COG1653	transport
BZ16_1726	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZ16_1727	COG1988	membrane-bound metal-dependent
BZ16_1729	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ16_1731	COG0823	Involved in the tonB-independent uptake of proteins
BZ16_1732	COG2814	Major facilitator Superfamily
BZ16_1733	COG3121	Chaperone
BZ16_1736	COG3121	Chaperone
BZ16_1737	COG3539	Fimbrial protein
BZ16_1740	COG0793	Belongs to the peptidase S41A family
BZ16_1742	COG1956	GAF domain-containing protein
BZ16_1743	COG2995	paraquat-inducible protein a
BZ16_1744	COG3008	intermembrane lipid transfer
BZ16_1748	COG3121	Chaperone
BZ16_1758	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BZ16_1761	COG5295	Hep Hag repeat protein
BZ16_1761	COG5295	Hep Hag repeat protein
BZ16_1762	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ16_1763	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BZ16_1764	COG0745	RESPONSE REGULATOR receiver
BZ16_1766	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BZ16_1767	COG0840	transmembrane signaling receptor activity
BZ16_1768	COG0840	transmembrane signaling receptor activity
BZ16_177	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BZ16_1771	COG0835	chemotaxis
BZ16_1772	COG0643	Histidine kinase
BZ16_1772	COG2198	Histidine kinase
BZ16_1773	COG1360	Flagellar Motor Protein
BZ16_1778	COG1285	pathogenesis
BZ16_1779	COG0840	transmembrane signaling receptor activity
BZ16_1781	COG1278	Cold shock
BZ16_1783	COG3321	synthase
BZ16_1783	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_1783	COG0604	alcohol dehydrogenase
BZ16_1786	COG1522	sequence-specific DNA binding
BZ16_1791	COG1733	regulation of RNA biosynthetic process
BZ16_1792	COG0702	epimerase
BZ16_1793	COG0840	transmembrane signaling receptor activity
BZ16_1796	COG0538	isocitrate dehydrogenase activity
BZ16_1797	COG1187	pseudouridine synthase activity
BZ16_1801	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BZ16_1803	COG0745	RESPONSE REGULATOR receiver
BZ16_1805	COG2850	peptidyl-arginine hydroxylation
BZ16_1807	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BZ16_1809	COG4591	ABC-type transport system involved in lipoprotein release permease component
BZ16_1811	COG4591	ABC-type transport system involved in lipoprotein release permease component
BZ16_1812	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BZ16_1813	COG3134	Outer membrane lipoprotein
BZ16_1816	COG1252	NADH dehydrogenase
BZ16_1821	COG5633	Lipoprotein
BZ16_1822	COG0537	adenosine 5'-monophosphoramidase activity
BZ16_1823	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BZ16_183	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ16_1830	COG4695	Portal protein
BZ16_1833	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ16_1833	COG1263	PTS System
BZ16_1834	COG0084	hydrolase, TatD family'
BZ16_1835	COG0470	DNA polymerase III
BZ16_1837	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BZ16_1838	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZ16_1839	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ16_184	COG1238	metal cluster binding
BZ16_1841	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_1845	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BZ16_1846	COG1399	metal-binding, possibly nucleic acid-binding protein
BZ16_1848	COG0564	pseudouridine synthase activity
BZ16_1850	COG1530	ribonuclease E activity
BZ16_1851	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BZ16_1857	COG3328	transposase activity
BZ16_1858	COG0628	permease
BZ16_1861	COG1560	Kdo2-lipid A biosynthetic process
BZ16_1862	COG3104	oligopeptide transport
BZ16_1863	COG5645	(Lipo)protein
BZ16_1864	COG2943	transferase activity, transferring hexosyl groups
BZ16_1865	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BZ16_187	COG4536	flavin adenine dinucleotide binding
BZ16_1870	COG2771	luxR family
BZ16_1871	COG3916	Acyl-homoserine-lactone synthase
BZ16_1872	COG0583	DNA-binding transcription factor activity
BZ16_1874	COG0477	Major facilitator Superfamily
BZ16_1876	COG0667	Aldo Keto reductase
BZ16_188	COG4137	Cytochrome C assembly protein
BZ16_1881	COG1203	CRISPR-associated helicase, Cas3
BZ16_1882	COG1518	maintenance of DNA repeat elements
BZ16_1883	COG0668	transmembrane transport
BZ16_1887	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BZ16_1888	COG0395	ABC-type sugar transport system, permease component
BZ16_189	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BZ16_1891	COG1609	Transcriptional regulator
BZ16_1893	COG3842	ATPase activity
BZ16_1896	COG3210	domain, Protein
BZ16_1899	COG3210	domain, Protein
BZ16_19	COG2814	Major facilitator Superfamily
BZ16_1900	COG2831	hemolysin activation secretion protein
BZ16_1901	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ16_1902	COG4638	Rieske (2fe-2S)
BZ16_1903	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ16_1904	COG0473	3-isopropylmalate dehydrogenase activity
BZ16_1905	COG0583	DNA-binding transcription factor activity
BZ16_1906	COG1609	Transcriptional regulator
BZ16_1907	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_1908	COG1129	ABC transporter
BZ16_1909	COG1879	ABC-type sugar transport system periplasmic component
BZ16_1910	COG1063	alcohol dehydrogenase
BZ16_1914	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BZ16_1920	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ16_1921	COG0765	amino acid transport
BZ16_1922	COG1126	abc transporter atp-binding protein
BZ16_1926	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BZ16_1929	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BZ16_1932	COG1169	isochorismate synthase
BZ16_1934	COG4575	ribosome binding
BZ16_1936	COG0129	dihydroxy-acid dehydratase activity
BZ16_1939	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ16_194	COG3137	Salt-induced outer membrane protein
BZ16_1940	COG1609	Transcriptional regulator
BZ16_1942	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_1943	COG3265	gluconokinase activity
BZ16_1944	COG2731	YhcH YjgK YiaL family protein
BZ16_1947	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ16_1948	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BZ16_195	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZ16_1950	COG0839	Belongs to the complex I subunit 6 family
BZ16_1953	COG1034	ATP synthesis coupled electron transport
BZ16_1955	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BZ16_1957	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ16_1959	COG0583	DNA-binding transcription factor activity
BZ16_196	COG3279	Response regulator of the LytR AlgR family
BZ16_1960	COG0436	Aminotransferase
BZ16_1963	COG0490	domain, Protein
BZ16_1963	COG0471	metal ion transport
BZ16_1964	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ16_1968	COG0857	belongs to the CobB CobQ family
BZ16_1968	COG0280	phosphate acetyltransferase
BZ16_1969	COG1609	Transcriptional regulator
BZ16_197	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZ16_1972	COG3037	sugar-specific permease SgaT UlaA
BZ16_1973	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BZ16_1974	COG0622	Phosphoesterase
BZ16_1976	COG1090	epimerase
BZ16_1977	COG4598	ABC transporter
BZ16_1978	COG4160	amino acid transport
BZ16_1979	COG4215	(ABC) transporter
BZ16_198	COG1605	Chorismate mutase
BZ16_198	COG0287	Prephenate dehydrogenase
BZ16_1980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ16_1981	COG0163	prenyltransferase activity
BZ16_1982	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BZ16_1983	COG1286	toxin biosynthetic process
BZ16_1984	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BZ16_1985	COG0285	dihydrofolate synthase activity
BZ16_1987	COG0586	Pfam SNARE associated Golgi protein
BZ16_1989	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZ16_1992	COG0697	spore germination
BZ16_1995	COG1794	racemase activity, acting on amino acids and derivatives
BZ16_1996	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ16_1999	COG3101	peptidyl-lysine hydroxylation
BZ16_2000	COG0730	response to heat
BZ16_2003	COG2890	protein-(glutamine-N5) methyltransferase activity
BZ16_2005	COG2062	phosphohistidine phosphatase, SixA
BZ16_2009	COG3691	Protein conserved in bacteria
BZ16_201	COG1605	Chorismate mutase
BZ16_201	COG0077	Prephenate dehydratase
BZ16_2012	COG4235	cytochrome complex assembly
BZ16_2012	COG3088	subunit of a heme lyase
BZ16_2013	COG3088	subunit of a heme lyase
BZ16_2013	COG4235	cytochrome complex assembly
BZ16_2014	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZ16_2015	COG1138	Cytochrome C-type biogenesis protein
BZ16_2017	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ16_2018	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ16_2019	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ16_202	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BZ16_2023	COG1704	LemA family
BZ16_2025	COG2824	Alkylphosphonate utilization operon protein PhnA
BZ16_203	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ16_2031	COG3501	Rhs element vgr protein
BZ16_204	COG0564	pseudouridine synthase activity
BZ16_2040	COG3188	usher protein
BZ16_2041	COG3121	Chaperone
BZ16_2053	COG2951	lytic endotransglycosylase activity
BZ16_206	COG0542	response to heat
BZ16_2061	COG0243	molybdopterin cofactor binding
BZ16_2062	COG0437	4 iron, 4 sulfur cluster binding
BZ16_2063	COG3302	dmso reductase anchor subunit
BZ16_2064	COG3381	protein complex oligomerization
BZ16_2070	COG3038	cytochrome b561
BZ16_2071	COG0436	Aminotransferase
BZ16_2076	COG0667	Aldo Keto reductase
BZ16_2079	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZ16_2090	COG3530	Putative quorum-sensing-regulated virulence factor
BZ16_2093	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BZ16_2094	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BZ16_2095	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ16_2097	COG2190	(PTS) system
BZ16_2098	COG2205	protein histidine kinase activity
BZ16_2099	COG0745	RESPONSE REGULATOR receiver
BZ16_2100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ16_2103	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BZ16_2105	COG0006	proline dipeptidase activity
BZ16_2106	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BZ16_2108	COG5002	protein histidine kinase activity
BZ16_2108	COG3850	Histidine kinase
BZ16_2109	COG0745	RESPONSE REGULATOR receiver
BZ16_2111	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BZ16_2113	COG4208	sulfate ABC transporter
BZ16_2114	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BZ16_2115	COG4150	thiosulfate binding
BZ16_2117	COG1737	Transcriptional regulator
BZ16_2118	COG2731	YhcH YjgK YiaL family protein
BZ16_2120	COG4886	Leucine-rich repeat (LRR) protein
BZ16_2122	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BZ16_2123	COG2837	iron assimilation
BZ16_2125	COG3111	PFAM Bacterial OB fold (BOF) protein
BZ16_213	COG5544	Lipoprotein
BZ16_2138	COG3005	denitrification pathway
BZ16_2139	COG3043	anaerobic respiration
BZ16_214	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BZ16_2141	COG3062	negative regulation of establishment of protein localization
BZ16_2142	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ16_2142	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ16_2143	COG2197	response regulator
BZ16_2145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ16_2147	COG1988	membrane-bound metal-dependent
BZ16_2148	COG0641	radical SAM
BZ16_2149	COG3119	arylsulfatase activity
BZ16_215	COG1042	CoA-binding domain protein
BZ16_215	COG0045	succinate-CoA ligase (ADP-forming) activity
BZ16_215	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ16_2150	COG3842	ATPase activity
BZ16_2151	COG1175	transmembrane transport
BZ16_2152	COG1840	ABC-type Fe3 transport system, periplasmic component
BZ16_2154	COG1393	Belongs to the ArsC family
BZ16_2156	COG1876	peptidase activity
BZ16_2160	COG2321	neutral zinc metallopeptidase
BZ16_2162	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BZ16_2164	COG2716	regulation of RNA biosynthetic process
BZ16_2165	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BZ16_2168	COG0628	permease
BZ16_2169	COG4783	chaperone-mediated protein folding
BZ16_217	COG3118	belongs to the thioredoxin family
BZ16_2170	COG1393	Belongs to the ArsC family
BZ16_2172	COG2233	PERMEase
BZ16_2175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BZ16_2176	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ16_2179	COG0581	inorganic phosphate transmembrane transporter activity
BZ16_218	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ16_2181	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BZ16_2182	COG0248	Ppx GppA phosphatase
BZ16_2183	COG2239	Acts as a magnesium transporter
BZ16_2184	COG0443	Heat shock 70 kDa protein
BZ16_2186	COG1177	transmembrane transport
BZ16_2187	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ16_2189	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BZ16_219	COG2814	Major facilitator Superfamily
BZ16_2191	COG3842	ATPase activity
BZ16_2196	COG2205	protein histidine kinase activity
BZ16_2197	COG0745	RESPONSE REGULATOR receiver
BZ16_2198	COG3422	double-strand break repair
BZ16_220	COG1566	PFAM secretion protein HlyD family protein
BZ16_221	COG1846	Transcriptional regulator
BZ16_2212	COG0517	IMP dehydrogenase activity
BZ16_2212	COG0516	GMP reductase activity
BZ16_2214	COG1645	bacterial-type flagellum-dependent swarming motility
BZ16_2217	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ16_2218	COG2976	Protein conserved in bacteria
BZ16_2226	COG3468	outer membrane autotransporter barrel domain protein
BZ16_2227	COG3468	outer membrane autotransporter barrel domain protein
BZ16_223	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BZ16_2230	COG2975	iron-sulfur cluster assembly
BZ16_2231	COG0633	Ferredoxin
BZ16_2235	COG0822	iron-sulfur transferase activity
BZ16_2236	COG1104	cysteine desulfurase activity
BZ16_2239	COG0483	inositol monophosphate 1-phosphatase activity
BZ16_224	COG2814	Major facilitator Superfamily
BZ16_2240	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BZ16_2241	COG3683	transport system, periplasmic component
BZ16_2242	COG2814	Major facilitator Superfamily
BZ16_2243	COG3711	transcriptional antiterminator
BZ16_2246	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ16_2246	COG1017	nitric oxide dioxygenase activity
BZ16_2247	COG2188	Transcriptional regulator
BZ16_2248	COG0347	Belongs to the P(II) protein family
BZ16_2249	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BZ16_2249	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ16_2250	COG2204	response regulator
BZ16_2251	COG3170	Tfp pilus assembly protein FimV
BZ16_2252	COG2205	protein histidine kinase activity
BZ16_2257	COG0590	tRNA wobble adenosine to inosine editing
BZ16_2258	COG0560	Phosphoserine phosphatase
BZ16_2260	COG1737	Transcriptional regulator
BZ16_2261	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ16_2267	COG0681	Belongs to the peptidase S26 family
BZ16_2270	COG3086	response to oxidative stress
BZ16_2271	COG3026	antisigma factor binding
BZ16_2272	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BZ16_2274	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BZ16_2276	COG0513	Belongs to the DEAD box helicase family
BZ16_2287	COG1984	allophanate hydrolase subunit 2
BZ16_2288	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BZ16_2290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BZ16_2291	COG5212	phosphodiesterase
BZ16_2293	COG3272	Protein of unknown function (DUF1722)
BZ16_2298	COG2205	protein histidine kinase activity
BZ16_2299	COG0745	RESPONSE REGULATOR receiver
BZ16_2303	COG0033	Phosphoglucomutase
BZ16_2304	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BZ16_2308	COG2169	Transcriptional regulator
BZ16_2308	COG1917	Cupin 2, conserved barrel domain protein
BZ16_2309	COG1447	Phosphotransferase system cellobiose-specific component IIA
BZ16_2310	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZ16_2311	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZ16_2313	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BZ16_2314	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BZ16_2316	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BZ16_2317	COG4413	Urea transporter
BZ16_2319	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BZ16_2326	COG1124	(ABC) transporter
BZ16_2327	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BZ16_2328	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ16_233	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BZ16_2330	COG0747	negative chemotaxis
BZ16_2331	COG1278	Cold shock
BZ16_2339	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZ16_2340	COG4175	Glycine betaine
BZ16_2341	COG4176	ABC-type proline glycine betaine transport system permease component
BZ16_2342	COG2113	Glycine betaine
BZ16_2344	COG1953	Uracil, thiamine, allantoin
BZ16_2346	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BZ16_2348	COG2226	methyltransferase
BZ16_2350	COG1388	LysM domain
BZ16_2350	COG0741	lytic transglycosylase activity
BZ16_2353	COG0656	L-ascorbic acid biosynthetic process
BZ16_2359	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BZ16_236	COG0436	Aminotransferase
BZ16_2361	COG2011	ABC-type metal ion transport system permease component
BZ16_2362	COG1464	Belongs to the NlpA lipoprotein family
BZ16_2364	COG1720	tRNA m6t6A37 methyltransferase activity
BZ16_2366	COG3015	lipoprotein NlpE involved in copper resistance
BZ16_2368	COG4681	YaeQ
BZ16_2370	COG4568	rho-dependent transcription termination
BZ16_2373	COG0346	lactoylglutathione lyase activity
BZ16_2375	COG0587	DNA-directed DNA polymerase activity
BZ16_2377	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BZ16_2381	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BZ16_2383	COG0750	zinc metalloprotease
BZ16_2384	COG0575	Belongs to the CDS family
BZ16_2385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BZ16_2391	COG0024	Methionine aminopeptidase
BZ16_2396	COG0564	pseudouridine synthase activity
BZ16_2397	COG3098	single-species biofilm formation
BZ16_2401	COG1611	Belongs to the LOG family
BZ16_2404	COG2363	Small membrane protein
BZ16_2405	COG0583	DNA-binding transcription factor activity
BZ16_2407	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BZ16_2408	COG2166	iron-sulfur cluster assembly
BZ16_2409	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BZ16_2410	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BZ16_2414	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZ16_2416	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BZ16_2417	COG1074	ATP-dependent DNA helicase activity
BZ16_2419	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BZ16_2430	COG0667	Aldo Keto reductase
BZ16_2436	COG0019	diaminopimelate decarboxylase activity
BZ16_2437	COG1609	Transcriptional regulator
BZ16_2438	COG2814	Major facilitator Superfamily
BZ16_2439	COG0583	DNA-binding transcription factor activity
BZ16_244	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
BZ16_2442	COG0840	transmembrane signaling receptor activity
BZ16_246	COG1960	acyl-CoA dehydrogenase activity
BZ16_2460	COG0288	reversible hydration of carbon dioxide
BZ16_2465	COG3119	arylsulfatase activity
BZ16_2466	COG1349	DNA-binding transcription factor activity
BZ16_2468	COG2222	sugar isomerase
BZ16_2469	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ16_2470	COG3715	PTS system
BZ16_2471	COG3716	PTS system mannose fructose sorbose family IID component
BZ16_2472	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ16_2474	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_2476	COG0641	radical SAM
BZ16_2477	COG3119	arylsulfatase activity
BZ16_2479	COG0191	fructose-bisphosphate aldolase activity
BZ16_248	COG3034	peptidoglycan biosynthetic process
BZ16_2483	COG2271	Major facilitator Superfamily
BZ16_2487	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ16_2487	COG1263	PTS System
BZ16_2488	COG1874	Beta-galactosidase
BZ16_2489	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BZ16_249	COG0121	glutamine amidotransferase
BZ16_2490	COG3833	ABC-type maltose transport systems, permease component
BZ16_2491	COG1175	transmembrane transport
BZ16_2492	COG2182	Extracellular solute-binding protein
BZ16_2494	COG1129	ABC transporter
BZ16_2495	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_2496	COG1879	ABC-type sugar transport system periplasmic component
BZ16_2498	COG0791	NLP P60 protein
BZ16_2499	COG1695	Transcriptional regulator
BZ16_250	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ16_251	COG1805	sodium ion transport
BZ16_2516	COG2944	sequence-specific DNA binding
BZ16_252	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ16_2521	COG4974	Belongs to the 'phage' integrase family
BZ16_2535	COG4695	Portal protein
BZ16_2559	COG0582	viral genome integration into host DNA
BZ16_256	COG1477	protein flavinylation
BZ16_2563	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BZ16_2564	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZ16_2565	COG4974	Belongs to the 'phage' integrase family
BZ16_2566	COG0716	FMN binding
BZ16_2567	COG4452	Inner membrane protein CreD
BZ16_2568	COG2205	protein histidine kinase activity
BZ16_2569	COG0745	RESPONSE REGULATOR receiver
BZ16_2570	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BZ16_2573	COG1272	protein, Hemolysin III
BZ16_2575	COG5295	Hep Hag repeat protein
BZ16_2580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ16_2581	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ16_2582	COG0006	proline dipeptidase activity
BZ16_2585	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BZ16_2586	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BZ16_2587	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BZ16_2592	COG0191	fructose-bisphosphate aldolase activity
BZ16_2595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BZ16_2596	COG0501	Belongs to the peptidase M48B family
BZ16_2598	COG1166	arginine decarboxylase activity
BZ16_26	COG1022	Amp-dependent synthetase and ligase
BZ16_260	COG2195	Cleaves the N-terminal amino acid of tripeptides
BZ16_2602	COG2356	endonuclease I
BZ16_2603	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BZ16_2604	COG0189	ligase activity
BZ16_2607	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ16_2609	COG2805	Type II/IV secretion system protein
BZ16_2610	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BZ16_2611	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BZ16_2612	COG0762	integral membrane protein
BZ16_2614	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BZ16_2615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZ16_2616	COG3064	Membrane
BZ16_2616	COG1073	alpha beta
BZ16_2616	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BZ16_2618	COG2066	Belongs to the glutaminase family
BZ16_2619	COG3171	Protein conserved in bacteria
BZ16_2621	COG1194	a g-specific adenine glycosylase
BZ16_2625	COG4774	siderophore transport
BZ16_2626	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_2627	COG1129	ABC transporter
BZ16_2628	COG1879	ABC-type sugar transport system periplasmic component
BZ16_2629	COG1982	Orn Lys Arg decarboxylase major
BZ16_2656	COG2771	luxR family
BZ16_2657	COG3916	Acyl-homoserine-lactone synthase
BZ16_2666	COG2211	Major facilitator Superfamily
BZ16_2668	COG1609	Transcriptional regulator
BZ16_2669	COG0471	metal ion transport
BZ16_2675	COG3209	COG3209 Rhs family protein
BZ16_2680	COG3209	COG3209 Rhs family protein
BZ16_2682	COG3501	Rhs element vgr protein
BZ16_2685	COG2610	gluconate transmembrane transporter activity
BZ16_2689	COG1132	(ABC) transporter
BZ16_2695	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ16_2695	COG2226	methyltransferase
BZ16_2695	COG3433	isochorismatase activity
BZ16_2696	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ16_2696	COG3433	isochorismatase activity
BZ16_2696	COG2226	methyltransferase
BZ16_2697	COG4771	TonB-dependent receptor
BZ16_2698	COG2195	Cleaves the N-terminal amino acid of tripeptides
BZ16_2699	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BZ16_27	COG0028	Belongs to the TPP enzyme family
BZ16_2705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ16_2706	COG3300	MHYT domain
BZ16_2706	COG5001	Diguanylate cyclase
BZ16_2708	COG2801	Transposase and inactivated derivatives
BZ16_2709	COG3133	Outer membrane lipoprotein
BZ16_271	COG2226	methyltransferase
BZ16_2714	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BZ16_2715	COG1191	sigma factor activity
BZ16_2720	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BZ16_2721	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BZ16_2722	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BZ16_2723	COG3710	Transcriptional regulator
BZ16_2727	COG1256	bacterial-type flagellum assembly
BZ16_2731	COG4786	Flagellar basal body rod
BZ16_2732	COG4787	bacterial-type flagellum-dependent cell motility
BZ16_2733	COG1749	Flagellar hook protein flgE
BZ16_2734	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BZ16_2735	COG1558	bacterial-type flagellum-dependent cell motility
BZ16_2736	COG1815	bacterial-type flagellum-dependent cell motility
BZ16_2737	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BZ16_2746	COG2204	response regulator
BZ16_2750	COG1987	bacterial-type flagellum assembly
BZ16_2751	COG1684	flagellar biosynthetic protein fliR
BZ16_2752	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ16_2756	COG4592	Periplasmic binding protein
BZ16_276	COG1940	carbohydrate kinase activity
BZ16_2761	COG3469	chitinase activity
BZ16_2762	COG3397	chitin binding
BZ16_2768	COG4964	Belongs to the GSP D family
BZ16_277	COG0419	ATPase involved in DNA repair
BZ16_2779	COG0848	biopolymer transport protein
BZ16_278	COG0420	3'-5' exonuclease activity
BZ16_2781	COG0811	peptide transport
BZ16_2782	COG0626	cystathionine gamma-synthase activity
BZ16_2783	COG0586	Pfam SNARE associated Golgi protein
BZ16_2784	COG2207	Transcriptional regulator
BZ16_2785	COG1979	alcohol dehydrogenase
BZ16_2786	COG0656	L-ascorbic acid biosynthetic process
BZ16_2788	COG2132	Multicopper oxidase
BZ16_2789	COG0204	Acyl-transferase
BZ16_279	COG0745	RESPONSE REGULATOR receiver
BZ16_2790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BZ16_2791	COG2249	NAD(P)H dehydrogenase (quinone) activity
BZ16_2792	COG0583	DNA-binding transcription factor activity
BZ16_2793	COG0187	DNA topoisomerase II activity
BZ16_2794	COG3150	esterase
BZ16_2795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BZ16_2796	COG3151	Protein conserved in bacteria
BZ16_2797	COG0494	nUDIX hydrolase
BZ16_2798	COG1538	Outer membrane efflux protein
BZ16_280	COG5002	protein histidine kinase activity
BZ16_2801	COG0754	glutathionylspermidine amidase activity
BZ16_2802	COG3384	dioxygenase
BZ16_2805	COG0531	amino acid
BZ16_2808	COG3025	triphosphatase activity
BZ16_2809	COG4991	sh3 domain protein
BZ16_2812	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BZ16_2816	COG0358	DNA primase activity
BZ16_2817	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZ16_282	COG1114	Component of the transport system for branched-chain amino acids
BZ16_2824	COG5301	cellulose 1,4-beta-cellobiosidase activity
BZ16_284	COG0366	Alpha amylase catalytic
BZ16_2842	COG4695	Portal protein
BZ16_2853	COG4974	Belongs to the 'phage' integrase family
BZ16_2866	COG0251	oxidation-reduction process
BZ16_287	COG0450	alkyl hydroperoxide reductase
BZ16_2874	COG1289	transmembrane transporter activity
BZ16_2878	COG0395	ABC-type sugar transport system, permease component
BZ16_288	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BZ16_2880	COG1653	transport
BZ16_2881	COG1609	Transcriptional regulator
BZ16_2882	COG3459	Glycosyltransferase 36 associated
BZ16_2883	COG3842	ATPase activity
BZ16_2887	COG3210	domain, Protein
BZ16_2896	COG3210	domain, Protein
BZ16_2898	COG3210	domain, Protein
BZ16_29	COG1609	Transcriptional regulator
BZ16_2900	COG3210	domain, Protein
BZ16_2901	COG2831	hemolysin activation secretion protein
BZ16_2902	COG4245	von Willebrand factor, type A
BZ16_2904	COG4245	von Willebrand factor, type A
BZ16_2905	COG4245	von Willebrand factor, type A
BZ16_2908	COG3247	response to pH
BZ16_2909	COG0446	pyridine nucleotide-disulphide oxidoreductase
BZ16_2909	COG1902	pentaerythritol trinitrate reductase activity
BZ16_291	COG1862	Preprotein translocase
BZ16_2912	COG1451	nucleotide metabolic process
BZ16_2913	COG0673	inositol 2-dehydrogenase activity
BZ16_2916	COG2721	sulfolactate sulfo-lyase activity
BZ16_2917	COG0246	Mannitol dehydrogenase
BZ16_2919	COG2271	Major facilitator Superfamily
BZ16_292	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BZ16_2922	COG0586	Pfam SNARE associated Golgi protein
BZ16_2925	COG4575	ribosome binding
BZ16_2926	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BZ16_2928	COG2259	Doxx family
BZ16_2929	COG0435	Glutathione S-transferase
BZ16_293	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BZ16_2930	COG0583	DNA-binding transcription factor activity
BZ16_2931	COG1741	Belongs to the pirin family
BZ16_2932	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BZ16_2936	COG2823	Periplasmic or secreted lipoprotein
BZ16_2938	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BZ16_2939	COG0784	Response regulator, receiver
BZ16_2939	COG2198	Histidine kinase
BZ16_2939	COG5002	protein histidine kinase activity
BZ16_2941	COG1242	4 iron, 4 sulfur cluster binding
BZ16_2942	COG0069	glutamate synthase activity
BZ16_2942	COG0067	glutamate synthase
BZ16_2942	COG0070	glutamate synthase
BZ16_2943	COG0493	'glutamate synthase
BZ16_2945	COG2969	positive regulation of protein catabolic process
BZ16_2946	COG0625	glutathione transferase activity
BZ16_2949	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BZ16_2950	COG3105	Protein conserved in bacteria
BZ16_2951	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ16_2952	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ16_2954	COG5007	Belongs to the BolA IbaG family
BZ16_2955	COG3113	response to antibiotic
BZ16_2956	COG2854	intermembrane phospholipid transfer
BZ16_2957	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BZ16_2958	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BZ16_2959	COG1127	ABC transporter
BZ16_296	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZ16_296	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZ16_2960	COG0530	calcium, potassium:sodium antiporter activity
BZ16_2961	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BZ16_2961	COG0517	IMP dehydrogenase activity
BZ16_2962	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BZ16_2963	COG3117	lipopolysaccharide transmembrane transporter activity
BZ16_2964	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BZ16_2965	COG1137	ATPase activity
BZ16_2966	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BZ16_2968	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ16_2970	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ16_2975	COG1609	Transcriptional regulator
BZ16_2976	COG1263	PTS System
BZ16_2976	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ16_2977	COG0366	Alpha amylase catalytic
BZ16_2978	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ16_2979	COG3783	Cytochrome b(562)
BZ16_2981	COG0312	modulator of DNA gyrase
BZ16_2983	COG2732	(Barnase) inhibitor
BZ16_2989	COG0583	DNA-binding transcription factor activity
BZ16_299	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BZ16_2998	COG0312	modulator of DNA gyrase
BZ16_2999	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ16_300	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BZ16_3000	COG3164	Protein of unknown function
BZ16_3001	COG1530	ribonuclease E activity
BZ16_3003	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BZ16_3004	COG1792	Involved in formation and maintenance of cell shape
BZ16_3005	COG1077	Cell shape determining protein MreB Mrl
BZ16_3006	COG2199	diguanylate cyclase activity
BZ16_3006	COG2200	EAL domain
BZ16_3007	COG0604	alcohol dehydrogenase
BZ16_3011	COG0511	ligase activity, forming carbon-carbon bonds
BZ16_3012	COG0439	Biotin carboxylase
BZ16_3014	COG3924	membrane
BZ16_3015	COG4145	pantothenate transmembrane transporter activity
BZ16_3017	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ16_3018	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BZ16_302	COG0142	geranyltranstransferase activity
BZ16_3022	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ16_3024	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZ16_3025	COG3133	Outer membrane lipoprotein
BZ16_3026	COG1278	Cold shock
BZ16_3027	COG1278	Cold shock
BZ16_3028	COG1278	Cold shock
BZ16_3031	COG0625	glutathione transferase activity
BZ16_3033	COG1069	ribulokinase activity
BZ16_3035	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_3036	COG1129	ABC transporter
BZ16_3038	COG1560	Kdo2-lipid A biosynthetic process
BZ16_3040	COG0025	NhaP-type Na H and K H
BZ16_3041	COG2252	PERMEase
BZ16_3042	COG3077	Addiction module antitoxin, RelB DinJ family
BZ16_3044	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ16_3046	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZ16_3047	COG0431	NADPH-dependent FMN reductase
BZ16_3049	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ16_305	COG0693	protein deglycase activity
BZ16_3050	COG1869	D-ribose catabolic process
BZ16_3051	COG2207	Transcriptional regulator
BZ16_3052	COG0673	inositol 2-dehydrogenase activity
BZ16_3054	COG3501	Rhs element vgr protein
BZ16_3056	COG3209	COG3209 Rhs family protein
BZ16_3058	COG3501	Rhs element vgr protein
BZ16_306	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BZ16_308	COG2814	Major facilitator Superfamily
BZ16_3081	COG1175	transmembrane transport
BZ16_3082	COG3833	ABC-type maltose transport systems, permease component
BZ16_3085	COG0527	aspartate kinase activity
BZ16_3089	COG1414	Transcriptional regulator
BZ16_3091	COG2224	Isocitrate lyase
BZ16_3092	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BZ16_310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BZ16_3104	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BZ16_3107	COG0551	DNA topoisomerase type I activity
BZ16_3109	COG0758	DNA mediated transformation
BZ16_311	COG1845	cytochrome c oxidase, subunit III
BZ16_3113	COG0569	domain protein
BZ16_3115	COG3036	rescue of stalled ribosome
BZ16_3116	COG0789	Transcriptional regulator
BZ16_3119	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BZ16_312	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BZ16_3122	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BZ16_3123	COG0201	protein transport
BZ16_3125	COG1841	ribosomal large subunit assembly
BZ16_313	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BZ16_3133	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BZ16_3134	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BZ16_3136	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BZ16_3137	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BZ16_3139	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BZ16_3144	COG0051	transcription antitermination factor activity, RNA binding
BZ16_3149	COG0049	tRNA binding
BZ16_315	COG2223	nitrite transmembrane transporter activity
BZ16_3150	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BZ16_3154	COG2964	Protein conserved in bacteria
BZ16_3155	COG0545	Peptidyl-prolyl cis-trans isomerase
BZ16_3157	COG1047	Peptidyl-prolyl cis-trans
BZ16_3158	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BZ16_316	COG3056	Lipoprotein
BZ16_3161	COG0488	(ABC) transporter
BZ16_3162	COG1216	Glycosyl transferase, family 2
BZ16_3164	COG2175	clavaminate synthase activity
BZ16_3165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ16_3167	COG4521	taurine ABC transporter
BZ16_3169	COG0429	hydrolase of the alpha beta-hydrolase fold
BZ16_317	COG0271	Belongs to the BolA IbaG family
BZ16_3171	COG3954	Phosphoribulokinase
BZ16_3173	COG1765	OsmC-like protein
BZ16_3175	COG1289	transmembrane transporter activity
BZ16_3178	COG0433	COG0433 Predicted ATPase
BZ16_3179	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZ16_3181	COG1486	melibiose metabolic process
BZ16_3185	COG0402	S-adenosylhomocysteine deaminase activity
BZ16_3186	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BZ16_3187	COG2146	nitrite reductase [NAD(P)H] activity
BZ16_3190	COG0180	Tryptophanyl-tRNA synthetase
BZ16_3192	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BZ16_3197	COG4796	Type ii and iii secretion system protein
BZ16_3202	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BZ16_3203	COG0494	nUDIX hydrolase
BZ16_3206	COG1011	Hydrolase
BZ16_3207	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BZ16_3211	COG0745	RESPONSE REGULATOR receiver
BZ16_3212	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ16_3213	COG2183	response to ionizing radiation
BZ16_3214	COG1918	ferrous iron import across plasma membrane
BZ16_322	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BZ16_3221	COG1640	4-alpha-glucanotransferase
BZ16_3222	COG0058	SHG alpha-glucan phosphorylase activity
BZ16_3226	COG1349	DNA-binding transcription factor activity
BZ16_3229	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZ16_323	COG0776	regulation of translation
BZ16_3230	COG0058	SHG alpha-glucan phosphorylase activity
BZ16_3235	COG3275	phosphorelay sensor kinase activity
BZ16_324	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ16_3240	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZ16_3242	COG2095	MarC family integral membrane protein
BZ16_3245	COG3157	Type VI secretion system effector, Hcp
BZ16_3246	COG3265	gluconokinase activity
BZ16_3247	COG2610	gluconate transmembrane transporter activity
BZ16_3248	COG1609	Transcriptional regulator
BZ16_3249	COG1741	Belongs to the pirin family
BZ16_325	COG1555	photosystem II stabilization
BZ16_3251	COG0745	RESPONSE REGULATOR receiver
BZ16_3253	COG0191	fructose-bisphosphate aldolase activity
BZ16_3255	COG1879	ABC-type sugar transport system periplasmic component
BZ16_3256	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_326	COG0824	Thioesterase
BZ16_3274	COG2081	HI0933 family
BZ16_3275	COG0306	phosphate transporter
BZ16_3277	COG0589	response to stress
BZ16_328	COG4533	DNA binding
BZ16_3281	COG0339	signal peptide processing
BZ16_3282	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BZ16_3283	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ16_3284	COG3835	regulator
BZ16_3285	COG2610	gluconate transmembrane transporter activity
BZ16_3286	COG1929	Belongs to the glycerate kinase type-1 family
BZ16_3291	COG1295	ribonuclease BN
BZ16_3292	COG2134	cdp-diacylglycerol pyrophosphatase
BZ16_3293	COG2982	Protein involved in outer membrane biogenesis
BZ16_3294	COG2200	EAL domain
BZ16_3295	COG1942	4-Oxalocrotonate Tautomerase
BZ16_3296	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ16_3297	COG0612	Peptidase, M16
BZ16_33	COG3116	cell division
BZ16_3302	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZ16_3303	COG2199	diguanylate cyclase activity
BZ16_3303	COG2200	EAL domain
BZ16_3304	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
BZ16_3305	COG4608	Belongs to the ABC transporter superfamily
BZ16_3306	COG0444	Belongs to the ABC transporter superfamily
BZ16_3307	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ16_3308	COG0601	transmembrane transport
BZ16_3309	COG0747	negative chemotaxis
BZ16_331	COG1522	sequence-specific DNA binding
BZ16_3311	COG2831	hemolysin activation secretion protein
BZ16_3315	COG2271	Major facilitator Superfamily
BZ16_3316	COG3851	Histidine kinase
BZ16_3317	COG2197	response regulator
BZ16_3318	COG2194	sulfuric ester hydrolase activity
BZ16_332	COG1132	(ABC) transporter
BZ16_3324	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BZ16_3327	COG4607	ABC-type enterochelin transport system periplasmic component
BZ16_3329	COG4605	iron ion homeostasis
BZ16_333	COG1132	(ABC) transporter
BZ16_3331	COG4604	ABC transporter, ATP-binding protein
BZ16_3334	COG0582	viral genome integration into host DNA
BZ16_3338	COG2003	Belongs to the UPF0758 family
BZ16_334	COG0347	Belongs to the P(II) protein family
BZ16_3346	COG1715	Restriction endonuclease
BZ16_3348	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BZ16_335	COG0004	ammonium transporteR
BZ16_3354	COG0582	viral genome integration into host DNA
BZ16_3356	COG1609	Transcriptional regulator
BZ16_3356	COG2207	Transcriptional regulator
BZ16_3357	COG4214	carbohydrate transport
BZ16_3359	COG4213	ABC transporter substrate-binding protein
BZ16_336	COG1946	Acyl-CoA thioesterase
BZ16_3361	COG1070	Carbohydrate kinase
BZ16_3363	COG3121	Chaperone
BZ16_3364	COG3188	usher protein
BZ16_3366	COG3274	enterobacterial common antigen metabolic process
BZ16_3368	COG2801	Transposase and inactivated derivatives
BZ16_3369	COG2423	ornithine cyclodeaminase activity
BZ16_337	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BZ16_3370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BZ16_3371	COG0823	Involved in the tonB-independent uptake of proteins
BZ16_3372	COG5645	(Lipo)protein
BZ16_3376	COG3977	Valine--pyruvate aminotransferase
BZ16_3378	COG0366	Alpha amylase catalytic
BZ16_338	COG3695	enzyme binding
BZ16_3381	COG2885	chlorophyll binding
BZ16_3383	COG2818	Glycosylase
BZ16_3387	COG2213	PTS system mannitol-specific
BZ16_3387	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ16_3389	COG3722	fumarate hydratase activity
BZ16_3395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZ16_3397	COG3383	formate dehydrogenase (NAD+) activity
BZ16_3397	COG0243	molybdopterin cofactor binding
BZ16_3398	COG3383	formate dehydrogenase (NAD+) activity
BZ16_3398	COG0243	molybdopterin cofactor binding
BZ16_3399	COG0437	4 iron, 4 sulfur cluster binding
BZ16_34	COG0768	penicillin binding
BZ16_3400	COG2864	formate dehydrogenase
BZ16_3403	COG3276	selenocysteine insertion sequence binding
BZ16_3410	COG2186	Transcriptional regulator
BZ16_3412	COG0477	Major facilitator Superfamily
BZ16_3413	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ16_3419	COG1522	sequence-specific DNA binding
BZ16_342	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BZ16_3420	COG0716	FMN binding
BZ16_3423	COG3312	ion transport
BZ16_3433	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BZ16_3435	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BZ16_3436	COG0573	inorganic phosphate transmembrane transporter activity
BZ16_3437	COG0581	inorganic phosphate transmembrane transporter activity
BZ16_3439	COG0704	Plays a role in the regulation of phosphate uptake
BZ16_344	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ16_3441	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ16_3442	COG0765	amino acid transport
BZ16_3443	COG0765	amino acid transport
BZ16_3444	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ16_3445	COG2252	PERMEase
BZ16_345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ16_3450	COG0706	membrane insertase activity
BZ16_3453	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BZ16_3456	COG0592	DNA-directed DNA polymerase activity
BZ16_3458	COG0187	DNA topoisomerase II activity
BZ16_3459	COG0561	phosphatase activity
BZ16_346	COG1309	transcriptional regulator
BZ16_3462	COG2801	Transposase and inactivated derivatives
BZ16_3467	COG3328	transposase activity
BZ16_3468	COG1763	Mo-molybdopterin cofactor biosynthetic process
BZ16_347	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BZ16_3470	COG3084	Protein conserved in bacteria
BZ16_3471	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BZ16_3472	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZ16_3473	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ16_3473	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ16_3476	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZ16_3478	COG3852	Histidine kinase
BZ16_3479	COG0174	glutamine synthetase
BZ16_348	COG1196	nuclear chromosome segregation
BZ16_348	COG3264	Mechanosensitive ion channel
BZ16_3481	COG1011	Hydrolase
BZ16_3484	COG0456	acetyltransferase
BZ16_3485	COG2982	Protein involved in outer membrane biogenesis
BZ16_3486	COG2233	PERMEase
BZ16_3487	COG0786	glutamate:sodium symporter activity
BZ16_3488	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BZ16_3489	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ16_3490	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BZ16_3491	COG1758	RNA polymerase activity
BZ16_3494	COG2860	membrane
BZ16_3495	COG1561	YicC-like family, N-terminal region
BZ16_35	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BZ16_350	COG2832	Protein of unknown function (DUF454)
BZ16_3500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BZ16_3503	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BZ16_3507	COG1519	Transferase
BZ16_3508	COG0859	PFAM glycosyl transferase family 9
BZ16_3509	COG0859	PFAM glycosyl transferase family 9
BZ16_3511	COG0156	8-amino-7-oxononanoate synthase activity
BZ16_3513	COG2861	carbohydrate metabolic process
BZ16_3514	COG4942	peptidase
BZ16_3516	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BZ16_3517	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ16_352	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BZ16_3520	COG1045	serine acetyltransferase
BZ16_3521	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BZ16_3522	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZ16_3522	COG2169	Transcriptional regulator
BZ16_3523	COG2205	protein histidine kinase activity
BZ16_3524	COG0745	RESPONSE REGULATOR receiver
BZ16_3525	COG3678	ATP-independent chaperone mediated protein folding
BZ16_3530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BZ16_3532	COG0471	metal ion transport
BZ16_3533	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BZ16_3534	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BZ16_3535	COG0583	DNA-binding transcription factor activity
BZ16_3538	COG3152	Membrane
BZ16_3540	COG1494	fructose-1,6-bisphosphatase
BZ16_3541	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BZ16_3542	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BZ16_3549	COG1575	Belongs to the MenA family. Type 1 subfamily
BZ16_3552	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZ16_3553	COG1609	Transcriptional regulator
BZ16_3555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BZ16_3557	COG4682	membrane
BZ16_3558	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BZ16_3559	COG0626	cystathionine gamma-synthase activity
BZ16_3560	COG0527	aspartate kinase activity
BZ16_3560	COG0460	homoserine dehydrogenase
BZ16_3567	COG1629	transport
BZ16_3572	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ16_3573	COG0678	peroxiredoxin activity
BZ16_3573	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ16_3589	COG1879	ABC-type sugar transport system periplasmic component
BZ16_3590	COG1129	ABC transporter
BZ16_3591	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_3593	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_3594	COG3085	chromosome segregation
BZ16_3597	COG3978	acetolactate synthase activity
BZ16_3598	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZ16_36	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BZ16_3606	COG0583	DNA-binding transcription factor activity
BZ16_3619	COG3121	Chaperone
BZ16_362	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ16_3622	COG3121	Chaperone
BZ16_3625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ16_3629	COG3118	belongs to the thioredoxin family
BZ16_3630	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BZ16_3631	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BZ16_3632	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZ16_3633	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BZ16_3634	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BZ16_3635	COG1088	dTDP-glucose 4,6-dehydratase activity
BZ16_3636	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BZ16_3637	COG0456	acetyltransferase
BZ16_3638	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BZ16_3639	COG2244	polysaccharide biosynthetic process
BZ16_3643	COG1113	amino acid transport
BZ16_3648	COG3071	HemY protein
BZ16_3649	COG2959	enzyme of heme biosynthesis
BZ16_3650	COG1587	Uroporphyrinogen-III synthase
BZ16_3652	COG3072	Adenylate cyclase
BZ16_3654	COG3328	transposase activity
BZ16_3657	COG5567	small periplasmic lipoprotein
BZ16_3659	COG3159	Protein conserved in bacteria
BZ16_366	COG0438	transferase activity, transferring glycosyl groups
BZ16_3660	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BZ16_3661	COG1011	Hydrolase
BZ16_3662	COG0210	DNA helicase
BZ16_3664	COG5441	Belongs to the UPF0261 family
BZ16_3665	COG5564	TIM-barrel signal transduction protein
BZ16_3666	COG0598	Magnesium transport protein CorA
BZ16_3668	COG2050	protein possibly involved in aromatic compounds catabolism
BZ16_3669	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BZ16_3670	COG0514	ATP-dependent DNA helicase (RecQ)
BZ16_3671	COG1280	lysine exporter protein (LysE YggA)
BZ16_3672	COG1280	lysine exporter protein (LysE YggA)
BZ16_3673	COG2267	carboxylic ester hydrolase activity
BZ16_3674	COG0561	phosphatase activity
BZ16_3676	COG0584	glycerophosphoryl diester phosphodiesterase
BZ16_3677	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZ16_3679	COG0247	lactate metabolic process
BZ16_3681	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BZ16_3684	COG3714	YhhN family
BZ16_3687	COG3776	membrane
BZ16_3688	COG0742	ribosomal rna small subunit methyltransferase
BZ16_3689	COG0552	protein localization to endoplasmic reticulum
BZ16_3689	COG0552	protein localization to endoplasmic reticulum
BZ16_369	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BZ16_369	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ16_3690	COG2884	Cell division ATP-binding protein ftsE
BZ16_3691	COG2177	Part of the ABC transporter FtsEX involved in
BZ16_3694	COG0683	leucine binding
BZ16_3695	COG0559	Belongs to the binding-protein-dependent transport system permease family
BZ16_3696	COG4177	L-phenylalanine transmembrane transporter activity
BZ16_3697	COG0411	ABC transporter
BZ16_3698	COG0410	ABC transporter
BZ16_3711	COG0584	glycerophosphoryl diester phosphodiesterase
BZ16_3712	COG0679	Auxin Efflux Carrier
BZ16_3715	COG0583	DNA-binding transcription factor activity
BZ16_3718	COG0412	Dienelactone hydrolase
BZ16_3719	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BZ16_3721	COG1966	Carbon starvation protein
BZ16_3722	COG0586	Pfam SNARE associated Golgi protein
BZ16_3723	COG1322	Protein conserved in bacteria
BZ16_3727	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZ16_3729	COG0805	protein transport
BZ16_3738	COG1739	Uncharacterized protein family UPF0029
BZ16_3739	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BZ16_374	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BZ16_3740	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BZ16_3755	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZ16_3756	COG0250	Participates in transcription elongation, termination and antitermination
BZ16_376	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZ16_3767	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BZ16_3769	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BZ16_377	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ16_3774	COG1515	deoxyribonuclease V activity
BZ16_3775	COG3068	Protein conserved in bacteria
BZ16_3778	COG0151	Belongs to the GarS family
BZ16_378	COG4651	solute:proton antiporter activity
BZ16_378	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BZ16_3786	COG2801	Transposase and inactivated derivatives
BZ16_379	COG2223	nitrite transmembrane transporter activity
BZ16_3791	COG3162	membrane
BZ16_3793	COG1301	dicarboxylic acid transport
BZ16_3794	COG2197	response regulator
BZ16_380	COG0737	Belongs to the 5'-nucleotidase family
BZ16_381	COG0737	Belongs to the 5'-nucleotidase family
BZ16_3815	COG2391	methyltransferase activity
BZ16_3816	COG0425	Belongs to the sulfur carrier protein TusA family
BZ16_3817	COG0583	DNA-binding transcription factor activity
BZ16_3818	COG0814	amino acid
BZ16_3819	COG0626	cystathionine gamma-synthase activity
BZ16_3821	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ16_3822	COG4558	Periplasmic binding protein
BZ16_3823	COG3720	iron ion transport
BZ16_3824	COG4771	TonB-dependent receptor
BZ16_3826	COG0702	epimerase
BZ16_3827	COG3721	Heme iron utilization protein
BZ16_3832	COG1358	cellular component organization or biogenesis
BZ16_384	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BZ16_3844	COG3121	Chaperone
BZ16_385	COG3735	TraB family
BZ16_3851	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BZ16_3853	COG0735	belongs to the Fur family
BZ16_3854	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ16_3857	COG0305	Participates in initiation and elongation during chromosome replication
BZ16_3858	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BZ16_3859	COG1448	Aminotransferase
BZ16_386	COG2217	Heavy metal translocating P-type atpase
BZ16_3860	COG2315	Protein conserved in bacteria
BZ16_3861	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BZ16_3862	COG0629	single-stranded DNA binding
BZ16_3864	COG1454	alcohol dehydrogenase
BZ16_387	COG0789	Transcriptional regulator
BZ16_3877	COG1309	transcriptional regulator
BZ16_3878	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ16_3878	COG0493	'glutamate synthase
BZ16_3879	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ16_388	COG1585	Membrane protein implicated in regulation of membrane protease activity
BZ16_3880	COG3383	formate dehydrogenase (NAD+) activity
BZ16_3883	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZ16_389	COG0330	HflC and HflK could
BZ16_3891	COG2076	Multidrug Resistance protein
BZ16_3892	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BZ16_3894	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BZ16_3895	COG1053	succinate dehydrogenase
BZ16_3897	COG1511	domain protein
BZ16_3897	COG3264	Mechanosensitive ion channel
BZ16_39	COG0772	Belongs to the SEDS family
BZ16_390	COG3118	belongs to the thioredoxin family
BZ16_3906	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BZ16_3907	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BZ16_3907	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BZ16_3908	COG0802	atpase or kinase
BZ16_3909	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZ16_391	COG0300	oxidoreductase activity
BZ16_3913	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BZ16_3914	COG0330	HflC and HflK could
BZ16_3915	COG0330	HflC and HflK could
BZ16_3916	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BZ16_3919	COG0557	exoribonuclease II activity
BZ16_392	COG2755	lipolytic protein G-D-S-L family
BZ16_3920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ16_3921	COG1960	acyl-CoA dehydrogenase activity
BZ16_3922	COG3650	response to hydrogen peroxide
BZ16_3923	COG1073	alpha beta
BZ16_3925	COG0360	Binds together with S18 to 16S ribosomal RNA
BZ16_3926	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BZ16_3929	COG3061	Opacity-associated protein A
BZ16_393	COG4181	ATPase activity
BZ16_3930	COG0545	Peptidyl-prolyl cis-trans isomerase
BZ16_3932	COG0737	Belongs to the 5'-nucleotidase family
BZ16_3934	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BZ16_3936	COG1253	flavin adenine dinucleotide binding
BZ16_3938	COG0729	surface antigen
BZ16_3939	COG2911	Protein conserved in bacteria
BZ16_394	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BZ16_3940	COG2105	PFAM AIG2 family protein
BZ16_3941	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BZ16_3943	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BZ16_3947	COG3423	Transcriptional regulator
BZ16_3949	COG0142	geranyltranstransferase activity
BZ16_395	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BZ16_3952	COG0697	spore germination
BZ16_3954	COG0642	Histidine kinase
BZ16_3955	COG0745	RESPONSE REGULATOR receiver
BZ16_3956	COG2027	D-alanyl-D-alanine carboxypeptidase
BZ16_3957	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ16_3958	COG1534	Rna-binding protein
BZ16_396	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BZ16_3960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZ16_3961	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BZ16_3963	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZ16_3967	COG0195	Participates in both transcription termination and antitermination
BZ16_3974	COG0513	Belongs to the DEAD box helicase family
BZ16_3977	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BZ16_398	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZ16_3980	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ16_3985	COG3153	acetyltransferase
BZ16_3989	COG1653	transport
BZ16_3991	COG0395	ABC-type sugar transport system, permease component
BZ16_3992	COG3842	ATPase activity
BZ16_3995	COG0702	epimerase
BZ16_3996	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BZ16_3997	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BZ16_3998	COG3454	Phosphonate metabolism
BZ16_3999	COG4778	phosphonate C-P lyase system protein PhnL
BZ16_400	COG2501	S4 domain
BZ16_4000	COG4107	phosphonate C-P lyase system protein PhnK
BZ16_4001	COG3627	carbon phosphorus lyase activity
BZ16_4002	COG3626	phosphonate metabolism
BZ16_4003	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BZ16_4004	COG3624	Phosphonate C-P lyase system protein PhnG
BZ16_4005	COG2188	Transcriptional regulator
BZ16_4009	COG4608	Belongs to the ABC transporter superfamily
BZ16_4010	COG0444	Belongs to the ABC transporter superfamily
BZ16_4011	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ16_4012	COG0601	transmembrane transport
BZ16_4014	COG2731	YhcH YjgK YiaL family protein
BZ16_4016	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BZ16_4019	COG2927	DNA polymerase III (CHI subunit)
BZ16_4021	COG0795	lipopolysaccharide-transporting ATPase activity
BZ16_4022	COG0795	lipopolysaccharide-transporting ATPase activity
BZ16_4028	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ16_4028	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ16_4028	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZ16_4036	COG2390	Transcriptional regulator
BZ16_4038	COG0859	PFAM glycosyl transferase family 9
BZ16_4040	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BZ16_4046	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ16_4047	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ16_4050	COG3706	GGDEF domain
BZ16_4056	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BZ16_4057	COG0456	acetyltransferase
BZ16_4059	COG2823	Periplasmic or secreted lipoprotein
BZ16_4061	COG4667	esterase of the alpha-beta hydrolase superfamily
BZ16_4062	COG0084	hydrolase, TatD family'
BZ16_4063	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZ16_4064	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BZ16_4068	COG3726	membrane protein affecting hemolysin expression
BZ16_4069	COG0560	Phosphoserine phosphatase
BZ16_407	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BZ16_4073	COG0488	(ABC) transporter
BZ16_4074	COG2885	chlorophyll binding
BZ16_4075	COG2199	diguanylate cyclase activity
BZ16_4078	COG0741	lytic transglycosylase activity
BZ16_408	COG4589	Belongs to the CDS family
BZ16_4080	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BZ16_4081	COG2207	Transcriptional regulator
BZ16_4081	COG3708	Transcriptional regulator
BZ16_4084	COG3045	CreA protein
BZ16_4085	COG0745	RESPONSE REGULATOR receiver
BZ16_4093	COG0521	Mo-molybdopterin cofactor biosynthetic process
BZ16_4096	COG1584	GPR1 FUN34 yaaH family protein
BZ16_410	COG2267	carboxylic ester hydrolase activity
BZ16_4100	COG0583	DNA-binding transcription factor activity
BZ16_4102	COG0196	riboflavin kinase activity
BZ16_4105	COG1047	Peptidyl-prolyl cis-trans
BZ16_4109	COG0505	Belongs to the CarA family
BZ16_411	COG0671	phosphoesterase, PA-phosphatase related
BZ16_411	COG2453	phosphatase
BZ16_4110	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BZ16_4112	COG2966	Psort location CytoplasmicMembrane, score
BZ16_4114	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BZ16_4120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ16_4123	COG0564	pseudouridine synthase activity
BZ16_4133	COG3501	Rhs element vgr protein
BZ16_4135	COG4886	Leucine-rich repeat (LRR) protein
BZ16_4135	COG4886	Leucine-rich repeat (LRR) protein
BZ16_4144	COG2801	Transposase and inactivated derivatives
BZ16_4146	COG1192	Involved in chromosome partitioning
BZ16_4147	COG1475	DNA binding
BZ16_4149	COG3609	addiction module antidote protein, CC2985 family
BZ16_415	COG0667	Aldo Keto reductase
BZ16_4151	COG5599	Phosphatase
BZ16_4156	COG2801	Transposase and inactivated derivatives
BZ16_416	COG0656	L-ascorbic acid biosynthetic process
BZ16_4161	COG2801	Transposase and inactivated derivatives
BZ16_4182	COG2801	Transposase and inactivated derivatives
BZ16_4186	COG2963	transposase activity
BZ16_4187	COG5599	Phosphatase
BZ16_4188	COG1317	bacterial-type flagellum organization
BZ16_4190	COG4669	(LipO)protein
BZ16_4199	COG2207	Transcriptional regulator
BZ16_4201	COG4792	protein secretion
BZ16_4202	COG4791	protein targeting
BZ16_4203	COG4794	Type iii secretion
BZ16_4204	COG4790	Type iii secretion
BZ16_4205	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BZ16_421	COG1187	pseudouridine synthase activity
BZ16_4214	COG4789	Type iii secretion
BZ16_422	COG2850	peptidyl-arginine hydroxylation
BZ16_4221	COG3328	transposase activity
BZ16_43	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BZ16_432	COG3423	Transcriptional regulator
BZ16_433	COG4953	penicillin-binding protein 1C
BZ16_434	COG2373	Large extracellular alpha-helical protein
BZ16_438	COG3962	Belongs to the TPP enzyme family
BZ16_439	COG0673	inositol 2-dehydrogenase activity
BZ16_44	COG0849	cell division
BZ16_440	COG1879	ABC-type sugar transport system periplasmic component
BZ16_441	COG1129	ABC transporter
BZ16_442	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_443	COG0673	inositol 2-dehydrogenase activity
BZ16_444	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ16_446	COG3718	enzyme involved in inositol metabolism
BZ16_448	COG5265	(ABC) transporter
BZ16_45	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BZ16_452	COG2197	response regulator
BZ16_453	COG1278	Cold shock
BZ16_454	COG1278	Cold shock
BZ16_456	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZ16_460	COG1686	Belongs to the peptidase S11 family
BZ16_461	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZ16_462	COG0772	Belongs to the SEDS family
BZ16_463	COG0768	penicillin binding
BZ16_465	COG0799	negative regulation of ribosome biogenesis
BZ16_467	COG1466	dna polymerase III delta subunit
BZ16_470	COG2888	peptidyl-tyrosine sulfation
BZ16_471	COG1126	abc transporter atp-binding protein
BZ16_472	COG0765	amino acid transport
BZ16_473	COG0765	amino acid transport
BZ16_475	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BZ16_476	COG4535	Mg2 and Co2 transporter CorC
BZ16_478	COG1702	phosphate starvation-inducible protein PhoH
BZ16_480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ16_487	COG0367	asparagine synthase
BZ16_488	COG0647	UMP catabolic process
BZ16_489	COG1940	carbohydrate kinase activity
BZ16_489	COG1846	Transcriptional regulator
BZ16_490	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BZ16_492	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ16_492	COG2190	(PTS) system
BZ16_492	COG1263	PTS System
BZ16_496	COG0735	belongs to the Fur family
BZ16_50	COG0494	nUDIX hydrolase
BZ16_500	COG0596	Alpha beta hydrolase
BZ16_502	COG2963	transposase activity
BZ16_503	COG0582	viral genome integration into host DNA
BZ16_509	COG2003	Belongs to the UPF0758 family
BZ16_51	COG1943	Transposase
BZ16_513	COG3596	GTP binding
BZ16_514	COG4983	Phage plasmid primase, P4 family domain protein
BZ16_521	COG0582	viral genome integration into host DNA
BZ16_523	COG2867	negative regulation of translational initiation
BZ16_525	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ16_526	COG0497	DNA recombination
BZ16_530	COG2009	succinate dehydrogenase
BZ16_531	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BZ16_532	COG1053	succinate dehydrogenase
BZ16_534	COG0567	Dehydrogenase, E1 component
BZ16_535	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZ16_537	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BZ16_538	COG1271	oxidase subunit
BZ16_539	COG1294	oxidase, subunit
BZ16_54	COG0237	dephospho-CoA kinase activity
BZ16_540	COG4890	Cyd operon protein YbgT
BZ16_541	COG3790	cyd operon protein YbgE
BZ16_542	COG0824	Thioesterase
BZ16_543	COG0811	peptide transport
BZ16_544	COG0848	biopolymer transport protein
BZ16_545	COG3064	Membrane
BZ16_545	COG3064	Membrane
BZ16_547	COG2885	chlorophyll binding
BZ16_548	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BZ16_556	COG1230	cation diffusion facilitator family transporter
BZ16_558	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZ16_56	COG3328	transposase activity
BZ16_561	COG2017	converts alpha-aldose to the beta-anomer
BZ16_563	COG1085	galactose-1-phosphate uridylyltransferase
BZ16_564	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BZ16_567	COG1119	ATPase activity
BZ16_568	COG3585	molybdate ion transport
BZ16_568	COG2005	Transcriptional regulator
BZ16_57	COG1459	type II secretion system
BZ16_570	COG0725	ABC transporter, periplasmic molybdate-binding protein
BZ16_571	COG4149	molybdate abc transporter
BZ16_573	COG0561	phosphatase activity
BZ16_578	COG2226	methyltransferase
BZ16_579	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BZ16_58	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BZ16_582	COG4628	conserved protein (DUF2132)
BZ16_583	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BZ16_585	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BZ16_587	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BZ16_588	COG0314	molybdopterin synthase activity
BZ16_589	COG0670	Belongs to the BI1 family
BZ16_59	COG4969	Belongs to the N-Me-Phe pilin family
BZ16_593	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ16_594	COG0583	DNA-binding transcription factor activity
BZ16_596	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BZ16_597	COG2211	Major facilitator Superfamily
BZ16_6	COG2885	chlorophyll binding
BZ16_6	COG3047	cAMP biosynthetic process
BZ16_602	COG1902	pentaerythritol trinitrate reductase activity
BZ16_604	COG0842	Transport permease protein
BZ16_605	COG0842	Transport permease protein
BZ16_606	COG1131	(ABC) transporter
BZ16_608	COG1309	transcriptional regulator
BZ16_609	COG0513	Belongs to the DEAD box helicase family
BZ16_61	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ16_616	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ16_618	COG1686	Belongs to the peptidase S11 family
BZ16_619	COG0277	FAD linked oxidase domain protein
BZ16_62	COG3725	Membrane protein required for beta-lactamase induction
BZ16_621	COG1403	HNH endonuclease
BZ16_623	COG2261	transglycosylase associated protein
BZ16_625	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BZ16_628	COG4807	Protein conserved in bacteria
BZ16_63	COG1113	amino acid transport
BZ16_632	COG1122	ATPase activity
BZ16_633	COG0410	ABC transporter
BZ16_636	COG2897	thiosulfate sulfurtransferase activity
BZ16_637	COG1732	Glycine betaine
BZ16_638	COG1174	glycine betaine transport
BZ16_639	COG1125	glycine betaine transport
BZ16_64	COG2186	Transcriptional regulator
BZ16_640	COG1174	glycine betaine transport
BZ16_641	COG0531	amino acid
BZ16_642	COG1982	Orn Lys Arg decarboxylase major
BZ16_644	COG0697	spore germination
BZ16_649	COG0814	amino acid
BZ16_65	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BZ16_652	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ16_657	COG0784	Response regulator, receiver
BZ16_657	COG2205	protein histidine kinase activity
BZ16_659	COG2198	Histidine kinase
BZ16_659	COG0642	Histidine kinase
BZ16_66	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZ16_660	COG2223	nitrite transmembrane transporter activity
BZ16_662	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BZ16_665	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BZ16_67	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ16_673	COG3395	kinase activity
BZ16_674	COG0235	Class ii aldolase
BZ16_675	COG1349	DNA-binding transcription factor activity
BZ16_676	COG3622	Belongs to the hyi family
BZ16_68	COG1049	propionate catabolic process, 2-methylcitrate cycle
BZ16_680	COG4386	tail sheath protein
BZ16_688	COG3299	homolog of phage Mu protein gp47
BZ16_691	COG1737	Transcriptional regulator
BZ16_693	COG2723	6-phospho-beta-galactosidase activity
BZ16_698	COG3157	Type VI secretion system effector, Hcp
BZ16_70	COG0697	spore germination
BZ16_701	COG3083	sulfuric ester hydrolase activity
BZ16_702	COG3082	Protein of unknown function (DUF1414)
BZ16_705	COG1061	Type III restriction enzyme res subunit
BZ16_706	COG1187	pseudouridine synthase activity
BZ16_707	COG2814	Major facilitator Superfamily
BZ16_709	COG4172	Belongs to the ABC transporter superfamily
BZ16_710	COG4239	(ABC) transporter, permease
BZ16_711	COG4174	ABC transporter (Permease)
BZ16_712	COG4166	transmembrane transport
BZ16_713	COG2200	EAL domain
BZ16_714	COG0791	NLP P60 protein
BZ16_715	COG0671	phosphoesterase, PA-phosphatase related
BZ16_716	COG0523	cobalamin synthesis protein
BZ16_718	COG2186	Transcriptional regulator
BZ16_719	COG0246	Mannitol dehydrogenase
BZ16_724	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_732	COG1129	ABC transporter
BZ16_733	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_734	COG0494	nUDIX hydrolase
BZ16_736	COG1105	Belongs to the carbohydrate kinase PfkB family
BZ16_737	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ16_737	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BZ16_737	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ16_738	COG3710	Transcriptional regulator
BZ16_74	COG2132	Multicopper oxidase
BZ16_741	COG3121	Chaperone
BZ16_742	COG3188	usher protein
BZ16_744	COG2855	membrane
BZ16_745	COG0583	DNA-binding transcription factor activity
BZ16_747	COG0833	amino acid
BZ16_749	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ16_75	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BZ16_751	COG4771	TonB-dependent receptor
BZ16_752	COG0625	glutathione transferase activity
BZ16_757	COG2011	ABC-type metal ion transport system permease component
BZ16_758	COG1686	Belongs to the peptidase S11 family
BZ16_759	COG0814	amino acid
BZ16_76	COG0288	reversible hydration of carbon dioxide
BZ16_760	COG1349	DNA-binding transcription factor activity
BZ16_761	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BZ16_762	COG0671	phosphoesterase, PA-phosphatase related
BZ16_764	COG0569	domain protein
BZ16_764	COG2985	domain, Protein
BZ16_765	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ16_768	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BZ16_769	COG3842	ATPase activity
BZ16_77	COG1131	(ABC) transporter
BZ16_770	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ16_771	COG1177	transmembrane transport
BZ16_774	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ16_777	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ16_778	COG1120	ATPase activity
BZ16_78	COG0842	Transport permease protein
BZ16_782	COG4160	amino acid transport
BZ16_783	COG4215	(ABC) transporter
BZ16_784	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ16_785	COG1126	abc transporter atp-binding protein
BZ16_786	COG1605	Chorismate mutase
BZ16_788	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ16_789	COG0702	epimerase
BZ16_79	COG0726	polysaccharide deacetylase
BZ16_790	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BZ16_791	COG0028	Belongs to the TPP enzyme family
BZ16_792	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ16_794	COG2431	L-lysine efflux transmembrane transporter activity
BZ16_795	COG3593	DNA synthesis involved in DNA repair
BZ16_796	COG2990	Protein conserved in bacteria
BZ16_797	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ16_799	COG1278	Cold shock
BZ16_801	COG0542	response to heat
BZ16_802	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BZ16_804	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BZ16_806	COG0492	ferredoxin-NADP+ reductase activity
BZ16_808	COG3107	peptidoglycan biosynthetic process
BZ16_808	COG1674	ftsk spoiiie
BZ16_811	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZ16_813	COG2814	Major facilitator Superfamily
BZ16_814	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BZ16_816	COG1882	Formate acetyltransferase
BZ16_817	COG2116	formate transmembrane transporter activity
BZ16_818	COG1944	ATP diphosphatase activity
BZ16_819	COG0252	asparaginase activity
BZ16_825	COG0539	negative regulation of cytoplasmic translation
BZ16_828	COG0658	competence protein
BZ16_828	COG2333	competence protein COMEC
BZ16_83	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BZ16_831	COG5383	Protein conserved in bacteria
BZ16_832	COG1278	Cold shock
BZ16_833	COG2835	tetraacyldisaccharide 4'-kinase activity
BZ16_835	COG3173	Aminoglycoside phosphotransferase
BZ16_836	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BZ16_837	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BZ16_838	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BZ16_84	COG0617	tRNA 3'-terminal CCA addition
BZ16_840	COG2989	Protein conserved in bacteria
BZ16_841	COG3108	Peptidase M15
BZ16_842	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZ16_843	COG1448	Aminotransferase
BZ16_847	COG0308	aminopeptidase N
BZ16_848	COG3328	transposase activity
BZ16_851	COG0633	Ferredoxin
BZ16_851	COG3217	Mosc domain protein beta barrel domain protein
BZ16_853	COG0488	(ABC) transporter
BZ16_854	COG2995	paraquat-inducible protein a
BZ16_855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BZ16_855	COG3008	intermembrane lipid transfer
BZ16_856	COG3009	Protein conserved in bacteria
BZ16_857	COG1943	Transposase
BZ16_858	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ16_86	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BZ16_861	COG1067	ATP-dependent peptidase activity
BZ16_863	COG2885	chlorophyll binding
BZ16_863	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BZ16_865	COG3070	regulator of competence-specific genes
BZ16_866	COG1289	transmembrane transporter activity
BZ16_867	COG3304	Inner membrane component domain
BZ16_868	COG0210	DNA helicase
BZ16_870	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BZ16_871	COG1832	CoA-binding protein
BZ16_875	COG2920	part of a sulfur-relay system
BZ16_88	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BZ16_882	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_884	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BZ16_885	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ16_886	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_887	COG3425	synthase
BZ16_889	COG1024	Enoyl-CoA hydratase
BZ16_89	COG1643	Atp-dependent helicase
BZ16_890	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_892	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BZ16_893	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BZ16_90	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BZ16_91	COG1120	ATPase activity
BZ16_92	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZ16_920	COG0488	(ABC) transporter
BZ16_923	COG0303	'Molybdopterin
BZ16_926	COG1136	(ABC) transporter
BZ16_93	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ16_932	COG0583	DNA-binding transcription factor activity
BZ16_933	COG0477	Major facilitator Superfamily
BZ16_935	COG2311	Membrane
BZ16_938	COG4211	Belongs to the binding-protein-dependent transport system permease family
BZ16_939	COG2949	membrane
BZ16_942	COG1346	cytolysis
BZ16_944	COG2814	Major facilitator Superfamily
BZ16_949	COG0489	protein tyrosine kinase activity
BZ16_952	COG2982	Protein involved in outer membrane biogenesis
BZ16_953	COG1253	flavin adenine dinucleotide binding
BZ16_954	COG4114	ferric iron reductase
BZ16_955	COG0076	glutamate decarboxylase activity
BZ16_956	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BZ16_959	COG1120	ATPase activity
BZ16_960	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ16_961	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ16_962	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZ16_965	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BZ16_966	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BZ16_968	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BZ16_968	COG0140	phosphoribosyl-ATP diphosphatase activity
BZ16_97	COG2860	membrane
BZ16_971	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BZ16_976	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ16_979	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ16_980	COG1129	ABC transporter
BZ16_981	COG0371	Dehydrogenase
BZ16_983	COG0531	amino acid
BZ16_984	COG2925	Exonuclease
BZ16_987	COG1388	LysM domain
BZ16_987	COG1470	cell adhesion involved in biofilm formation
BZ16_988	COG2271	Major facilitator Superfamily
BZ16_989	COG3011	Protein conserved in bacteria
BZ16_990	COG1028	Short-chain dehydrogenase reductase Sdr
BZ16_992	COG4948	Mandelate Racemase Muconate Lactonizing
BZ16_996	COG0534	Mate efflux family protein