locus-tag class description YPK_0002 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) YPK_0003 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) YPK_0004 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPK_0005 ENOG410667J hydrolase YPK_0008 ENOG4105C7B Threonine dehydratase YPK_0009 ENOG4105D99 atp gtp-binding protein YPK_0010 ENOG4105R2A (LipO)protein YPK_0014 ENOG4105JKW Valine--pyruvate aminotransferase YPK_0016 ENOG4107T9C Alpha amylase catalytic region YPK_0019 ENOG4108ZG0 Ompa motb domain protein YPK_0021 ENOG4108R3E Dna-3-methyladenine glycosylase i YPK_0025 ENOG4106JH6 (LipO)protein YPK_0026 ENOG4105CTS PTS system mannitol-specific YPK_0028 ENOG4105E61 Mannitol repressor protein YPK_0030 ENOG4108YYI Protein of unknown function (DUF2810) YPK_0034 ENOG4105C8Q Methyl-accepting chemotaxis YPK_0035 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) YPK_0037 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) YPK_0038 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) YPK_0039 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein YPK_0040 ENOG4108MG3 formate dehydrogenase YPK_0043 ENOG4105EM7 Selenocysteine-specific translation elongation factor YPK_0050 ENOG4105MEV Acyl-transferase YPK_0051 ENOG4106EAR Fimbrial protein YPK_0053 ENOG4108TTM chaperone YPK_0055 ENOG4105CMG Carbohydrate kinase YPK_0057 ENOG4105DFW ABC transporter YPK_0059 ENOG4107RNG ABC transporter YPK_0060 ENOG4105T16 Transcriptional regulator (AraC family) YPK_0061 ENOG4105DFP Integrase YPK_0067 ENOG4105CMM transposase YPK_0068 ENOG4108IPW abc transporter atp-binding protein YPK_0069 ENOG4105CM4 permease protein YPK_0075 ENOG4105C6T cysteine synthase YPK_0078 ENOG4105C85 amino acid YPK_0080 ENOG4105DIJ Phosphoethanolamine transferase YPK_0081 ENOG4108KX4 response regulator YPK_0082 ENOG4105BZU Histidine kinase YPK_0083 ENOG4105CXY transporter YPK_0086 ENOG4105D5K Hemolysin activator protein YPK_0088 ENOG4105DEF Extracellular solute-binding protein, family 5 YPK_0089 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component YPK_0090 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPK_0091 ENOG4105C3U ABC transporter YPK_0092 ENOG4108JQ7 (ABC) transporter YPK_0093 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) YPK_0094 ENOG4105BZU Histidine kinase YPK_0095 ENOG4108PU9 oligogalacturonate-specific porin YPK_0100 ENOG4105CS0 peptidase YPK_0101 ENOG4107SS6 2-dehydro-3-deoxygluconokinase YPK_0102 ENOG4105VSH 4-oxalocrotonate tautomerase YPK_0103 ENOG4105CMB EAL domain-containing protein YPK_0104 ENOG41066T0 asmA family YPK_0105 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) YPK_0106 ENOG4107H3J ribonuclease YPK_0111 ENOG4105BZW Glycerate kinase YPK_0112 ENOG4107QQ0 gntp family YPK_0113 ENOG4107VHA regulatoR YPK_0114 ENOG4105DC8 reductase YPK_0115 ENOG4105D6S protein involved in catabolism of external DNA YPK_0116 ENOG4105DGW oligopeptidase A YPK_0120 ENOG4108M6U Universal stress protein A YPK_0122 ENOG4105CJ3 phosphate transporter YPK_0123 ENOG4105CBX hi0933 family YPK_0126 ENOG4105CNN ABC, transporter YPK_0127 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPK_0129 ENOG4105D2N Aldolase YPK_0131 ENOG4105DPZ Two component transcriptional regulator (Winged helix family YPK_0133 ENOG4105C2I pirin domain protein YPK_0134 ENOG4105DIQ Transcriptional regulator YPK_0135 ENOG4105C6Z Gluconate YPK_0136 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family YPK_0140 ENOG41076UM multiple antibiotic resistance (MarC)-related protein YPK_0141 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) YPK_0146 ENOG4108HRK Histidine kinase YPK_0151 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) YPK_0152 ENOG4105C6V Glycerol-3-phosphate dehydrogenase YPK_0157 ENOG4105E98 transcriptional regulator DeoR family YPK_0161 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) YPK_0162 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) YPK_0164 ENOG4105MJ2 Competence protein YPK_0166 ENOG4105RID UPF0379 protein yhcN YPK_0169 ENOG4105XFK Ferrous iron transport protein A YPK_0170 ENOG4105BZM domain protein YPK_0171 ENOG4108RRZ Transcription elongation factor GreB YPK_0172 ENOG4105DPZ Two component transcriptional regulator (Winged helix family YPK_0173 ENOG4105E0F Histidine kinase YPK_0176 ENOG4105VEJ Heat shock protein YPK_0177 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 YPK_0178 ENOG4105DQY intracellular growth attenuator YPK_0180 ENOG4107RK2 ADP-ribose diphosphatase NudE YPK_0182 ENOG4105UZW Tail fiber assembly protein YPK_0199 ENOG4105NVB glycoside hydrolase, family 19 YPK_0202 ENOG4105ZIA Phage protein gp16 YPK_0217 ENOG4105HVQ Regulatory factor of maltose metabolism YPK_0219 ENOG4108JQC penicillin-binding protein 1A YPK_0224 ENOG4105E4G Type IV pilus YPK_0229 ENOG4105DJV ribulose-phosphate 3-epimerase YPK_0230 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) YPK_0231 ENOG4105C31 Tryptophanyl-tRNA synthetase YPK_0233 ENOG4107V9H nitrite transporter YPK_0234 ENOG4105WZK nitrite reductase NADPH small subunit YPK_0235 ENOG4107QZF nitrite reductase NADPH large subunit YPK_0237 ENOG4105DZC cytosine deaminase YPK_0240 ENOG41060NJ transcriptional regulator YPK_0241 ENOG4105F8D glycoside hydrolase family 4 YPK_0242 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) YPK_0243 ENOG4105D7A ATP-binding protein YPK_0245 ENOG4105C8Y Acetylornithine aminotransferase YPK_0247 ENOG410613R integral membrane protein, YccS YhfK family YPK_0249 ENOG4108UKZ OsmC family YPK_0251 ENOG4105GMB type VI secretion system effector, hcp1 family YPK_0254 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) YPK_0256 ENOG4105DNZ Alpha Beta Hydrolase YPK_0258 ENOG4106FTQ Taurine ABC transporter, periplasmic YPK_0260 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component YPK_0261 ENOG4105E2B Taurine dioxygenase YPK_0263 ENOG4105K64 Glycosyl transferase, family 2 YPK_0264 ENOG4105C5H ABC transporter YPK_0267 ENOG4105VKU nucleicacid-binding protein YPK_0268 ENOG4108YZY peptidylprolyl cis-trans isomerase YPK_0270 ENOG4108V1T peptidylprolyl cis-trans isomerase YPK_0271 ENOG4105WWK YheO domain protein YPK_0276 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) YPK_0279 ENOG4108RS6 transposase YPK_0287 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) YPK_0289 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) YPK_0290 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) YPK_0292 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal YPK_0301 ENOG4105VPB 50S ribosomal protein L30 YPK_0303 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) YPK_0304 ENOG41067V7 50S ribosomal protein L36 YPK_0307 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) YPK_0310 ENOG4105W1Y Transcriptional regulator YPK_0311 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system YPK_0313 ENOG4105C1A potassium transporter peripheral membrane YPK_0317 ENOG4105C79 DNA protecting protein DprA YPK_0319 ENOG4108WI1 Dna topoisomerase YPK_0322 ENOG4108Z0R Transferase YPK_0327 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase YPK_0333 ENOG4105PM1 preprotein translocase subunit SecE YPK_0334 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) YPK_0342 ENOG4105D41 biosynthesis protein thiH YPK_0345 ENOG4105D06 uba thif-type nad fad binding protein YPK_0347 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) YPK_0352 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) YPK_0353 ENOG4105R2J Conserved Protein YPK_0355 ENOG4108T8B Protein of unknown function (DUF1481) YPK_0356 ENOG4105C12 Phosphoribosylglycinamide synthetase YPK_0364 ENOG4107QP3 malate synthase g YPK_0365 ENOG4108I9X Isocitrate lyase YPK_0367 ENOG41069M3 Transcriptional regulator YPK_0368 ENOG4105C3R Methionine synthase YPK_0372 ENOG4105CFH Aspartokinase YPK_0376 ENOG4105EG2 ABC transporter, permease YPK_0377 ENOG4105D56 permease protein YPK_0378 ENOG4107FKK extracellular solute-binding protein family 1 YPK_0382 ENOG4107W52 maltose operon periplasmic protein YPK_0385 ENOG4108WC9 type VI secretion system effector, hcp1 family YPK_0395 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPK_0401 ENOG4105CS6 Rhs element vgr protein YPK_0403 ENOG4105CNA YD repeat protein YPK_0410 ENOG4105CNA YD repeat protein YPK_0412 ENOG4105CS6 Rhs element vgr protein YPK_0414 ENOG4107TYG Oxidoreductase domain-containing protein YPK_0416 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) YPK_0417 ENOG4108RVA ribokinase YPK_0418 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) YPK_0421 ENOG4105GVF (ABC) transporter YPK_0423 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component YPK_0426 ENOG4105C7N Xanthine uracil vitamin C permease YPK_0428 ENOG4105EEQ Na H antiporter YPK_0430 ENOG4105D1S lipid A biosynthesis YPK_0432 ENOG4105C2J ABC transporter YPK_0433 ENOG4105CNN ABC, transporter YPK_0435 ENOG4105EF1 ribulokinase YPK_0436 ENOG4105C2X Arabinose 5-phosphate isomerase YPK_0437 ENOG4105CYM Glutathione S-transferase YPK_0442 ENOG4105VEQ Cold shock protein YPK_0443 ENOG4105VEQ Cold shock protein YPK_0444 ENOG4105VEQ Cold shock protein YPK_0445 ENOG4108XTF Outer Membrane Lipoprotein YPK_0448 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase YPK_0449 ENOG4105CSH Transporter YPK_0452 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) YPK_0453 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) YPK_0455 ENOG4108IA2 Sodium pantothenate symporter YPK_0456 ENOG4105RG0 Membrane YPK_0458 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase YPK_0459 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein YPK_0463 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family YPK_0464 ENOG41062P1 Diguanylate cyclase phosphodiesterase YPK_0465 ENOG4105DFF Rod shape-determining protein mreb YPK_0466 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) YPK_0467 ENOG4105VQ7 Rod shape-determining protein MreD YPK_0469 ENOG4105C03 ribonuclease YPK_0470 ENOG4105QD6 exported protein YPK_0472 ENOG4105D1U peptidase U62 modulator of DNA gyrase YPK_0482 ENOG4105CR8 Transcriptional regulator YPK_0488 ENOG4105UNR (Barnase) inhibitor YPK_0490 ENOG4105CMS peptidase U62, modulator of DNA gyrase YPK_0492 ENOG4108XVM Cytochrome b(562) YPK_0493 ENOG4105NXH GreA GreB family elongation factor YPK_0494 ENOG4105CG3 alpha amylase, catalytic region YPK_0495 ENOG4105C5Y PTS System YPK_0496 ENOG4105D4X repressor YPK_0498 ENOG4105KME endoribonuclease L-psp YPK_0501 ENOG41080Z8 PHOSPHOCARRIER protein YPK_0503 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN YPK_0504 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA YPK_0505 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPK_0506 ENOG4108IUZ ABC transporter YPK_0507 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA YPK_0508 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) YPK_0509 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase YPK_0510 ENOG4105C2X Arabinose 5-phosphate isomerase YPK_0511 ENOG4105FEU K -dependent Na -Ca exchanger YPK_0512 ENOG4105DHJ ABC, transporter YPK_0513 ENOG4105CY3 ABC transporter, permease YPK_0514 ENOG4107PE3 Mammalian cell entry related domain protein YPK_0515 ENOG4105E3I toluene tolerance YPK_0516 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane YPK_0517 ENOG4105VFK BolA family YPK_0519 ENOG4105C0H protease YPK_0520 ENOG4105C0H protease YPK_0521 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III YPK_0523 ENOG4105D6Z AFG1 family ATPase YPK_0526 ENOG4107MKT Stringent starvation protein a YPK_0527 ENOG4105KB2 stringent starvation protein b YPK_0529 ENOG4105BZ8 glutamate synthase YPK_0530 ENOG4105CBC glutamate synthase YPK_0531 ENOG4105N5T Radical SAM Protein YPK_0533 ENOG4105BZU Histidine kinase YPK_0534 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain YPK_0536 ENOG4105W4M Transport-associated protein YPK_0540 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) YPK_0541 ENOG4108CNN domain protein YPK_0542 ENOG4105CWB LysR family transcriptional Regulator YPK_0543 ENOG4105CHF Glutathione S-transferase YPK_0544 ENOG4108VBZ doxx family YPK_0546 ENOG41090KG Inner membrane protein YqjE YPK_0547 ENOG4105NE1 Conserved Protein YPK_0550 ENOG4106W5V Membrane YPK_0553 ENOG4105DPW Major facilitator superfamily MFS_1 YPK_0555 ENOG4107QZW Altronate oxidoreductase YPK_0556 ENOG4105CTX dehydratase YPK_0557 ENOG4105P66 Membrane YPK_0559 ENOG4105EE0 oxidoreductase YPK_0560 ENOG4108VKG metal-dependent hydrolase YPK_0563 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase YPK_0564 ENOG4108YK4 Acid-resistance membrane protein YPK_0567 ENOG4108M24 von Willebrand factor, type A YPK_0570 ENOG4108M24 von Willebrand factor, type A YPK_0571 ENOG4105D5K Hemolysin activator protein YPK_0572 ENOG4105CKT filamentous hemagglutinin YPK_0577 ENOG4105CKT filamentous hemagglutinin YPK_0579 ENOG4105CKT filamentous hemagglutinin YPK_0582 ENOG4105CKT filamentous hemagglutinin YPK_0587 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 YPK_0588 ENOG4107KJX Transcriptional regulator YPK_0589 ENOG4108IJG ABC transporter substrate-binding protein YPK_0591 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component YPK_0593 ENOG4107QK4 glycoside hydrolase, family 3 domain protein YPK_0595 ENOG4108MI0 Resistance protein YPK_0596 ENOG4105J12 Multidrug resistance protein mdtN YPK_0599 ENOG4105CHM Aminotransferase YPK_0603 ENOG4105KME endoribonuclease L-psp YPK_0608 ENOG4105MZU cell filamentation protein YPK_0610 ENOG4105GMB type VI secretion system effector, hcp1 family YPK_0617 ENOG4105XB7 anti-repressor protein YPK_0634 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPK_0635 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) YPK_0636 ENOG4105VCC 30S ribosomal protein S21 YPK_0639 ENOG4107ZVW dihydroneopterin aldolase YPK_0642 ENOG4106MWK domain protein YPK_0643 ENOG4105I7R Adenylate cyclase YPK_0646 ENOG4105DVH amino acid YPK_0647 ENOG4105W0Z cytoplasmic protein YPK_0650 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b YPK_0651 ENOG4106032 Glutathionylspermidine synthase YPK_0654 ENOG4105DFG type I secretion outer membrane protein YPK_0655 ENOG41087AY ADP-Ribose pyrophosphatase YPK_0656 ENOG4108SX3 cytoplasmic protein YPK_0657 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) YPK_0658 ENOG4105IPS esterase YPK_0659 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPK_0660 ENOG4105CR8 Transcriptional regulator YPK_0661 ENOG4105NF4 modulator of drug activity YPK_0662 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPK_0663 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase YPK_0665 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) YPK_0667 ENOG4105CV8 reductase YPK_0668 ENOG4108I6A alcohol dehydrogenase YPK_0669 ENOG4105CF7 AraC family transcriptional regulator YPK_0670 ENOG4108K81 inner membrane protein YghB YPK_0671 ENOG4105C28 cystathionine YPK_0672 ENOG4105CWK Biopolymer transport protein, ExbB YPK_0673 ENOG4108ZZF transport protein (ExbD) YPK_0692 ENOG4108M1A Chitin-binding protein YPK_0693 ENOG4105E03 chitinase YPK_0695 ENOG4106PG1 outer membrane usher protein YPK_0696 ENOG4106P2F Pfam:Pili_assembly_C YPK_0698 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein YPK_0703 ENOG4105D00 flagellar biosynthetic protein flhB YPK_0704 ENOG4105D19 Role in flagellar biosynthesis (By similarity) YPK_0705 ENOG4105VS8 Flagellar biosynthetic protein fliq YPK_0706 ENOG4105CN7 Flagellar biosynthetic protein FliP YPK_0707 ENOG4105DD5 Flagellar motor switch protein YPK_0709 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family YPK_0711 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) YPK_0714 ENOG4108JIR Flagellum-specific ATP synthase YPK_0718 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA YPK_0719 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) YPK_0720 ENOG4108ZC9 flagellar basal-body rod protein flgc YPK_0721 ENOG4105W00 Flagellar hook capping protein YPK_0722 ENOG4105BZE flagellar hook protein, FlgE YPK_0725 ENOG4108M3R transcriptional activator CadC YPK_0730 ENOG4107RD7 Flagellar Motor Protein, MotA YPK_0736 ENOG4108XTF Outer Membrane Lipoprotein YPK_0737 ENOG4105BZU Histidine kinase YPK_0738 ENOG4105C1P efflux transporter, rnd family, mfp subunit YPK_0740 ENOG4105BZS acriflavin resistance protein YPK_0748 ENOG4105CFC Transporter YPK_0749 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) YPK_0750 ENOG4107ZSV Receptor YPK_0751 ENOG4105C0W non-ribosomal peptide synthetase YPK_0752 ENOG4105C0W non-ribosomal peptide synthetase YPK_0758 ENOG4105BZ1 (ABC) transporter YPK_0762 ENOG4107EFN gluconate transport system permease 3 YPK_0764 ENOG4105CS6 Rhs element vgr protein YPK_0766 ENOG4105CNA YD repeat protein YPK_0768 ENOG4105CNA YD repeat protein YPK_0770 ENOG4105CNA YD repeat protein YPK_0772 ENOG4105CNA YD repeat protein YPK_0777 ENOG41062WK cellular response to acidity YPK_0778 ENOG4105C8P )-transporter YPK_0779 ENOG4105ETE Transcriptional regulator (LacI family YPK_0781 ENOG4105CT4 transporter YPK_0783 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) YPK_0784 ENOG4105DUU IucA IucC family protein YPK_0802 ENOG4105CDV Ompa motb domain protein YPK_0804 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPK_0811 ENOG4105CXN decarboxylase YPK_0812 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPK_0813 ENOG4105C2J ABC transporter YPK_0814 ENOG4105CNN ABC, transporter YPK_0820 ENOG4105CEN a g-specific adenine glycosylase YPK_0822 ENOG41090ED Protein with unknown function (DUF469) YPK_0823 ENOG4105CSV Glutaminase YPK_0824 ENOG4105K33 Periplasmic Protein YPK_0825 ENOG4105EUK rtx toxin RtxA YPK_0826 ENOG4105CSA Coproporphyrinogen iii oxidase YPK_0827 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) YPK_0829 ENOG4108VIA integral membrane protein YPK_0831 ENOG4105II7 pyrroline-5-carboxylate reductase YPK_0832 ENOG4105DFA alanine racemase domain protein YPK_0833 ENOG4105CZX twitching motility protein YPK_0835 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) YPK_0838 ENOG4105D7Z glutathione synthase YPK_0839 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) YPK_0841 ENOG4105RWS endonuclease I YPK_0845 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) YPK_0846 ENOG4108RS6 transposase YPK_0848 ENOG4108RS6 transposase YPK_0849 ENOG4108K0D peptidase, M48 YPK_0850 ENOG4105CV1 Transketolase (EC 2.2.1.1) YPK_0853 ENOG4105D2N Aldolase YPK_0854 ENOG4105D64 Mechanosensitive ion channel YPK_0856 ENOG4105MPN Membrane YPK_0858 ENOG4105E66 phosphoriboisomerase A YPK_0859 ENOG4108JQ1 Dehydrogenase YPK_0860 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase YPK_0863 ENOG4107RAQ aminopeptidase YPK_0864 ENOG4105D0A hydroxylase YPK_0865 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family YPK_0873 ENOG4108UT2 hemolysin iii YPK_0876 ENOG4105Y75 tpr repeat protein YPK_0878 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPK_0879 ENOG4105EB3 Histidine kinase YPK_0880 ENOG4105CT7 inner membrane cred family protein YPK_0881 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) YPK_0884 ENOG4105MEH YPK_0888 ENOG4105DFE Dna adenine methylase YPK_0892 ENOG4105VZ1 Replication Protein YPK_0896 ENOG4105ED4 portal protein YPK_0920 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) YPK_0921 ENOG4105T95 Thiol disulfide interChange protein YPK_0922 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) YPK_0925 ENOG4105DFP Integrase YPK_0961 ENOG4105NTW Transcriptional regulator YPK_0962 ENOG4108UY0 (LipO)protein YPK_0964 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPK_0965 ENOG4105CNN ABC, transporter YPK_0968 ENOG4107FKK extracellular solute-binding protein family 1 YPK_0971 ENOG4105EG2 ABC transporter, permease YPK_0973 ENOG4105C4C beta-galactosidase YPK_0974 ENOG4105CI1 PTS System YPK_0976 ENOG4105ETE Transcriptional regulator (LacI family YPK_0978 ENOG4105DPW Major facilitator superfamily MFS_1 YPK_0979 ENOG4105ETE Transcriptional regulator (LacI family YPK_0982 ENOG4105D2N Aldolase YPK_0984 ENOG4105ENH Sulfatase YPK_0985 ENOG4105C4X radical SAM domain protein YPK_0987 ENOG4105CHR reductase YPK_0988 ENOG4105CE4 GlcNAc 6-P deacetylase YPK_0989 ENOG4108YTN IIa component YPK_0990 ENOG4105F3R pts system mannose fructose sorbose family iid YPK_0991 ENOG4105ETZ PTS System YPK_0992 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB YPK_0993 ENOG4105E70 isomerase YPK_0994 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of YPK_0995 ENOG4105E98 transcriptional regulator DeoR family YPK_0996 ENOG4105CBG Sulfatase YPK_1001 ENOG4107B2H carbonic anhydrase YPK_1005 ENOG4107QHF type ii secretion system protein e YPK_1006 ENOG4105D7Q type ii secretion system YPK_1018 ENOG4105C8Q Methyl-accepting chemotaxis YPK_1021 ENOG4105EJC lysr family transcriptional regulator YPK_1022 ENOG4105F27 Major Facilitator YPK_1023 ENOG4105RQF LysR family Transcriptional regulator YPK_1024 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) YPK_1025 ENOG41060NJ transcriptional regulator YPK_1031 ENOG4105CPC Aldo Keto reductase YPK_1034 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase YPK_1041 ENOG4105DSY exodeoxyribonuclease V, gamma YPK_1042 ENOG4107QXK peptidase YPK_1043 ENOG4107QKA exodeoxyribonuclease V beta YPK_1044 ENOG4107QYX exodeoxyribonuclease v alpha YPK_1046 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase YPK_1047 ENOG4105CA3 membrane-bound lytic murein transglycosylase YPK_1048 ENOG4105CUZ uba thif-type nad fad binding protein YPK_1049 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) YPK_1050 ENOG4105C9B Cysteine desulfurase YPK_1052 ENOG4105ETT transcriptional Regulator, LysR family YPK_1053 ENOG4105M08 Membrane YPK_1056 ENOG4105EWT decarboxylase family YPK_1059 ENOG4105WP7 tRNA pseudouridine synthase C YPK_1060 ENOG4105DR9 pseudouridine synthase YPK_1061 ENOG4105QDK Flavodoxin YPK_1065 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) YPK_1071 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) YPK_1072 ENOG4105KNE Phosphatidate cytidylyltransferase YPK_1073 ENOG4105DZP Membrane-associated zinc metalloprotease YPK_1075 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) YPK_1079 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) YPK_1081 ENOG4105C0B DNA polymerase III (alpha subunit) YPK_1083 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase YPK_1086 ENOG4105M1T rho-binding antiterminator YPK_1088 ENOG4108VWS Yaeq family YPK_1089 ENOG4108YZN class I peptide chain release factor YPK_1090 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion YPK_1092 ENOG4108R96 Methyltransferase, YaeB family YPK_1093 ENOG4108R8X outer membrane lipoprotein YPK_1094 ENOG4105D01 (LipO)protein YPK_1095 ENOG4108UMI ABC transporter, permease YPK_1097 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase YPK_1101 ENOG4105CV8 reductase YPK_1105 ENOG4105E9H Lytic Murein transglycosylase YPK_1107 ENOG4105D1A Methyltransferase YPK_1109 ENOG4108JDX DNA polymerase iii, epsilon subunit YPK_1110 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease YPK_1113 ENOG4105GIJ Glycine betaine YPK_1114 ENOG4108HQS Glycine betaine YPK_1115 ENOG4108IJ7 Glycine betaine YPK_1116 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) YPK_1121 ENOG4108WMJ Protein of unknown function (DUF2002) YPK_1122 ENOG4108SAJ Protein of unknown function (DUF1198) YPK_1124 ENOG4105VEQ Cold shock protein YPK_1125 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein YPK_1126 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component YPK_1127 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPK_1128 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) YPK_1129 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) YPK_1136 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) YPK_1140 ENOG4105XXV Acid-resistance protein YPK_1141 ENOG4107SVH Potassium channel protein YPK_1142 ENOG41086WQ Protein CrcB homolog YPK_1144 ENOG4105VZJ PTS System YPK_1145 ENOG4105CK1 PTS System YPK_1146 ENOG4105VCP PTS System YPK_1147 ENOG4105EZV Transcriptional regulator YPK_1152 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 YPK_1155 ENOG4105EEX Two component transcriptional regulator (Winged helix family YPK_1156 ENOG4105C08 Histidine kinase YPK_1160 ENOG4105XIQ Protein of unknown function (DUF2517) YPK_1162 ENOG4107SEY Conserved Protein YPK_1163 ENOG4105CVP deoxyribo-dipyrimidine photolyase YPK_1164 ENOG4107RF4 Phosphodiesterase YPK_1165 ENOG4107QNR UPF0135 protein YPK_1167 ENOG4105P4J Allophanate hydrolase, subunit 1 YPK_1168 ENOG4107R7A Allophanate hydrolase subunit 2 YPK_1179 ENOG4105C1J atp-dependent rna helicase YPK_1181 ENOG4108IYU L-aspartate oxidase YPK_1183 ENOG41069PW sigma-e factor negative regulatory protein YPK_1184 ENOG4105VQK sigma E regulatory protein, MucB RseB YPK_1185 ENOG4105WMJ Positive regulator of sigma E, RseC MucC YPK_1188 ENOG4105C3F Signal peptidase i YPK_1192 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) YPK_1194 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding YPK_1214 ENOG4105HRS Antitermination protein YPK_1248 ENOG4106G6Q Transcriptional regulator YPK_1250 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB YPK_1251 ENOG4108Z6B deaminase YPK_1257 ENOG4107WP9 Histidine kinase YPK_1258 ENOG4108SKK alpha helix protein YPK_1259 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family YPK_1261 ENOG4105C4K Nad synthetase YPK_1262 ENOG4108YZA Nitrogen regulatory protein pii YPK_1263 ENOG4108M21 YPK_1264 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) YPK_1269 ENOG4105D8G Major Facilitator superfamily YPK_1270 ENOG4108MN2 Stationary phase inducible protein CsiE YPK_1271 ENOG41065CD Exported protein YPK_1272 ENOG4105D7X high-affinity nickel-transporter YPK_1276 ENOG4105C3J Cysteine desulfurase YPK_1277 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins YPK_1281 ENOG4108ZIT Ferredoxin, 2FE-2S YPK_1282 ENOG4105WVQ Fe-S assembly protein IscX YPK_1285 ENOG4105YYA enhanced serine sensitivity protein SseB YPK_1286 ENOG4108MGN ATP-binding component of a transport system YPK_1295 ENOG4105N21 Membrane YPK_1296 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) YPK_1299 ENOG4105VPD cellular component movement YPK_1302 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) YPK_1304 ENOG4108WC9 type VI secretion system effector, hcp1 family YPK_1321 ENOG4105DWF phosphomethylpyrimidine kinase YPK_1323 ENOG4108ZGU inhibitor of vertebrate lysozyme YPK_1325 ENOG4105CFP Peptidase U32 YPK_1326 ENOG4105KWI UPF0339 protein YPK_1327 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPK_1328 ENOG4105EB3 Histidine kinase YPK_1333 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) YPK_1335 ENOG4108JPW Aminotransferase YPK_1337 ENOG4105F38 ABC transporter, permease YPK_1338 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component YPK_1340 ENOG4105R8A Heat shock protein YPK_1341 ENOG4105CJW magnesium transporter YPK_1343 ENOG4105C9X ppx gppa phosphatase YPK_1344 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) YPK_1345 ENOG4105C8U phosphate abc transporter YPK_1346 ENOG4105E2Z phosphate ABC transporter (Permease YPK_1348 ENOG4108C80 FliB family YPK_1349 ENOG4108MK9 spermidine N(1)-acetyltransferase YPK_1350 ENOG4108V3E phosphoribosylglycinamide formyltransferase YPK_1353 ENOG4105C2W permease YPK_1355 ENOG4105K89 arsenate reductase YPK_1356 ENOG4105ERG peptidase m48, ste24p YPK_1357 ENOG4105C02 permease YPK_1360 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen YPK_1361 ENOG4105RH4 Glycine cleavage system transcriptional repressor YPK_1363 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) YPK_1366 ENOG4105CGZ zinc metallopeptidase YPK_1373 ENOG4105KUZ arsenate reductase YPK_1375 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC YPK_1376 ENOG4107Z33 ABC transporter, permease YPK_1377 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) YPK_1378 ENOG4105ENH Sulfatase YPK_1379 ENOG4105C4X radical SAM domain protein YPK_1380 ENOG4105S2T inner membrane protein YbcI YPK_1382 ENOG4105BZS acriflavin resistance protein YPK_1384 ENOG4105WH1 Two component transcriptional regulator luxr family YPK_1385 ENOG4108ZNS ferredoxin-type protein NapF YPK_1386 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase YPK_1388 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) YPK_1389 ENOG4105CUW cytochrome C-TYPE protein YPK_1391 ENOG4105C6K Malic enzyme YPK_1397 ENOG4105H4F exported protein YPK_1398 ENOG4105E7K (LipO)protein YPK_1399 ENOG4105EZR dyp-type peroxidase family protein YPK_1405 ENOG4108R66 Conserved Protein YPK_1406 ENOG4105QEK Transcriptional regulator YPK_1408 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein YPK_1409 ENOG4108I5D sulfate abc transporter YPK_1410 ENOG4105ECW sulfate abc transporter YPK_1412 ENOG4105C6T cysteine synthase YPK_1413 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway YPK_1414 ENOG4105DPZ Two component transcriptional regulator (Winged helix family YPK_1415 ENOG41062D9 Histidine kinase YPK_1417 ENOG4105C87 Aminotransferase class I and II YPK_1418 ENOG4107RAQ aminopeptidase YPK_1420 ENOG4105E1V na solute symporter YPK_1423 ENOG4105DJY efflux transporter, rnd family, mfp subunit YPK_1424 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPK_1425 ENOG4105E0F Histidine kinase YPK_1426 ENOG4105C5Y PTS System YPK_1428 ENOG4105KZ7 phosphocarrier protein hpr YPK_1429 ENOG4105C6T cysteine synthase YPK_1430 ENOG4105EXN Sulfate transport protein CysZ YPK_1433 ENOG4105VRT cytoplasmic protein YPK_1438 ENOG4105D9N nucleoside YPK_1441 ENOG4105CPC Aldo Keto reductase YPK_1442 ENOG4105C5Q Transcriptional regulator YPK_1445 ENOG41072TH Protein of unknown function (DUF1479) YPK_1446 ENOG4105CHM Aminotransferase YPK_1447 ENOG4108VKM cytochrome b561 YPK_1449 ENOG4106B0W Curli production assembly transport component CsgG YPK_1451 ENOG4107Y60 (LipO)protein YPK_1453 ENOG4108NEM leader-binding protein dmsD YPK_1454 ENOG4107KGK dmso reductase anchor subunit YPK_1455 ENOG4105QAX Iron-sulfur YPK_1456 ENOG4107QY8 reductase YPK_1459 ENOG4108WC9 type VI secretion system effector, hcp1 family YPK_1464 ENOG4105CVE Lytic murein transglycosylase YPK_1474 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPK_1476 ENOG4105GQR Chaperone YPK_1477 ENOG4105CW0 outer membrane usher protein YPK_1486 ENOG4105CS6 Rhs element vgr protein YPK_1492 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA YPK_1494 ENOG4108V0P LemA family YPK_1497 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) YPK_1498 ENOG41060IM Heme exporter protein YPK_1499 ENOG4105X3C heme exporter protein YPK_1501 ENOG4105DA4 cytochrome c-type biogenesis protein YPK_1502 ENOG4107QX9 Thiol disulfide interChange protein YPK_1503 ENOG4105KWW Biogenesis protein YPK_1504 ENOG4105KWW Biogenesis protein YPK_1505 ENOG410903C (LipO)protein YPK_1506 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation YPK_1507 ENOG4105KZW UPF0381 protein YPK_1511 ENOG4108BY2 phosphohistidine phosphatase YPK_1513 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) YPK_1516 ENOG4105EJ9 Membrane YPK_1517 ENOG4108BPE -transporting atpase YPK_1518 ENOG4105MH2 YfcL protein YPK_1520 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPK_1523 ENOG4106WZ1 flagella biosynthesis regulator YPK_1524 ENOG410631K Membrane YPK_1528 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) YPK_1530 ENOG4105DQR SNARE associated Golgi YPK_1532 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase YPK_1533 ENOG4108S3P Sporulation domain protein YPK_1534 ENOG4105E96 Colicin v production protein YPK_1535 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase YPK_1536 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YPK_1538 ENOG4105E89 ABC transporter YPK_1539 ENOG4105DSP amino acid AbC transporter YPK_1540 ENOG4106YG3 ABC transporter YPK_1541 ENOG4108JEH abc transporter atp-binding protein YPK_1542 ENOG4105ECP epimerase YPK_1544 ENOG4108RE9 Phosphodiesterase YPK_1545 ENOG4105PTV Nudix Hydrolase YPK_1546 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC YPK_1549 ENOG4107P2S Transcriptional regulator YPK_1550 ENOG4105C6K Malic enzyme YPK_1554 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 YPK_1555 ENOG4107QWE )-transporter YPK_1558 ENOG4105CHM Aminotransferase YPK_1559 ENOG4107NQ8 LysR family Transcriptional regulator YPK_1561 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) YPK_1563 ENOG4105GKE subunit e YPK_1564 ENOG4107QIZ NADH dehydrogenase YPK_1565 ENOG4108IEH NADH dehydrogenase subunit g YPK_1568 ENOG4107UFS subunit j YPK_1570 ENOG4105D65 subunit l YPK_1571 ENOG4105C8S subunit m YPK_1574 ENOG4108R66 Conserved Protein YPK_1575 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family YPK_1576 ENOG4105CHR reductase YPK_1577 ENOG4105F32 YngK protein YPK_1578 ENOG4105K2J Transcriptional regulator YPK_1579 ENOG4105C5I Dehydrogenase YPK_1582 ENOG4105C01 Dihydroxy-acid dehydratase YPK_1585 ENOG4105TNS Conserved Protein YPK_1588 ENOG4105E4F Isochorismate synthase YPK_1591 ENOG4108IPT Naphthoate synthase YPK_1593 ENOG4105CEY Amp-dependent synthetase and ligase YPK_1594 ENOG4108MTB glycosyl transferase family YPK_1595 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction YPK_1597 ENOG4107SDU Methyl-accepting chemotaxis YPK_1598 ENOG4105CDA abc transporter atp-binding protein YPK_1599 ENOG4105E5Q amino acid AbC transporter YPK_1600 ENOG4107R0W ABC transporter YPK_1606 ENOG4108T1M outer membrane protein x YPK_1610 ENOG4105CPQ Dehydrogenase YPK_1611 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPK_1612 ENOG4105C2J ABC transporter YPK_1613 ENOG4105CNN ABC, transporter YPK_1614 ENOG4105FKQ transcriptional regulator YPK_1615 ENOG4105EJC lysr family transcriptional regulator YPK_1616 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) YPK_1618 ENOG4105C94 Transporter YPK_1619 ENOG4105DVW rieske (2Fe-2S) YPK_1620 ENOG4105E3J oxidoreductase YPK_1621 ENOG4105D5K Hemolysin activator protein YPK_1622 ENOG4105CKT filamentous hemagglutinin YPK_1625 ENOG4105CKT filamentous hemagglutinin YPK_1628 ENOG4105TIV Cryptic phage CTXphi transcriptional repressor RstR YPK_1629 ENOG4105CKT filamentous hemagglutinin YPK_1631 ENOG4108IJ9 (ABC) transporter YPK_1633 ENOG4105ETE Transcriptional regulator (LacI family YPK_1636 ENOG4105DRS transport system, permease YPK_1637 ENOG4105HY2 Glycosidase related protein YPK_1641 ENOG4105CUY Mechanosensitive ion channel YPK_1644 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) YPK_1645 ENOG4107IIZ CRISPR-associated helicase, Cas3 YPK_1646 ENOG4105ENG CRISPR-associated protein, Csy1 family YPK_1647 ENOG4105DZX CRISPR-associated protein, Csy2 family YPK_1648 ENOG4105M6W Crispr-associated protein, Csy3 family YPK_1649 ENOG4108Y1S CRISPR-associated protein, Csy4 family YPK_1650 ENOG4105CPC Aldo Keto reductase YPK_1652 ENOG4105C54 Major Facilitator superfamily YPK_1654 ENOG4105ETT transcriptional Regulator, LysR family YPK_1655 ENOG4105VJY transcriptional regulator YPK_1656 ENOG4107YC3 synthase YPK_1660 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) YPK_1661 ENOG4105DJ9 glucan biosynthesis protein YPK_1662 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) YPK_1663 ENOG4105NAC (LipO)protein YPK_1664 ENOG4105DUX Transporter YPK_1665 ENOG4105D1S lipid A biosynthesis YPK_1669 ENOG4105DSF transport protein YPK_1673 ENOG4105PVA Biofilm formation regulatory protein BssS YPK_1676 ENOG41067V3 Antibiotic biosynthesis monooxygenase YPK_1677 ENOG4107QQB Ribonuclease E YPK_1678 ENOG4105EI2 Pseudouridine synthase YPK_1679 ENOG4108RS6 transposase YPK_1681 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein YPK_1682 ENOG4105VGS 50s ribosomal protein l32 YPK_1685 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase YPK_1686 ENOG4105CHR reductase YPK_1688 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPK_1689 ENOG4105YAZ 4-amino-4-deoxychorismate lyase YPK_1690 ENOG4105HHA aminodeoxychorismate lyase YPK_1692 ENOG4107QRG dna polymerase iii YPK_1693 ENOG4105F8V Hydrolase, tatD family YPK_1694 ENOG4105CI1 PTS System YPK_1695 ENOG4105F9E Shikimate 5-dehydrogenase YPK_1696 ENOG4105K59 histidine triad (HIT) protein YPK_1697 ENOG41090DQ Lipoprotein YPK_1702 ENOG4105CEP NADH dehydrogenase YPK_1705 ENOG4107MBR 17 kDa surface antigen YPK_1706 ENOG4108JA2 transcriptioN-repair coupling factor YPK_1707 ENOG4105D60 lipoprotein releasing system transmembrane protein YPK_1709 ENOG4105D60 lipoprotein releasing system transmembrane protein YPK_1711 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) YPK_1713 ENOG4105EZE Cupin 4 family protein YPK_1715 ENOG4105XJC Two component transcriptional regulator (Winged helix family YPK_1718 ENOG4107QTF adenylosuccinate lyase YPK_1722 ENOG4108R99 pseudouridine synthase YPK_1723 ENOG4108HMX isocitrate dehydrogenase (NADP) YPK_1724 ENOG4106NDP Transcriptional regulator YPK_1726 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor YPK_1727 ENOG4105ECR NmrA family YPK_1728 ENOG4105KVH Transcriptional regulator YPK_1730 ENOG4105D6F Phosphatase YPK_1731 ENOG41061EV selenium-binding protein YdfZ YPK_1733 ENOG4108XM1 transcriptional regulator AsnC family YPK_1735 ENOG4105GSJ Inner membrane protein ylaC YPK_1740 ENOG4105VEQ Cold shock protein YPK_1742 ENOG4105C8Q Methyl-accepting chemotaxis YPK_1743 ENOG4105KT7 mgtC SapB transporter YPK_1744 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic YPK_1746 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region YPK_1747 ENOG4107RD7 Flagellar Motor Protein, MotA YPK_1748 ENOG4105ER2 Ompa motb domain protein YPK_1749 ENOG4105CBS Chea signal transduction histidine kinase YPK_1750 ENOG4108V3W Chemotaxis protein, CheW YPK_1753 ENOG4105C8Q Methyl-accepting chemotaxis YPK_1756 ENOG4105BZU Histidine kinase YPK_1758 ENOG4108VYJ response regulator receiver protein YPK_1759 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) YPK_1760 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase YPK_1764 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) YPK_1772 ENOG4105WT8 Protein of unknown function (DUF1480) YPK_1775 ENOG4105GQR Chaperone YPK_1779 ENOG4105DY2 Paraquat-inducible protein b YPK_1780 ENOG4105H2K paraquat-inducible protein a YPK_1781 ENOG4108ZGC gaf domain protein YPK_1783 ENOG4105CN1 protease YPK_1786 ENOG4105H8W Fimbrial protein YPK_1787 ENOG4108VEV chaperone YPK_1790 ENOG4108VEV chaperone YPK_1791 ENOG4105C0R drug resistance transporter emrb qaca subfamily YPK_1792 ENOG4105CAZ oligogalacturonide lyase YPK_1794 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase YPK_1795 ENOG4108ETY sodium dicarboxylate symporter YPK_1796 ENOG4107K5X Membrane-bound metal-dependent hydrolase YPK_1797 ENOG4108PU9 oligogalacturonate-specific porin YPK_1798 ENOG4105WEM extracellular solute-binding protein YPK_1800 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component YPK_1801 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component YPK_1802 ENOG41061NF Pectate lyase YPK_1803 ENOG4105CHR reductase YPK_1805 ENOG4105M5J Cupin 2, conserved barrel domain protein YPK_1808 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 YPK_1809 ENOG4107PN8 YfeABCD locus regulator YPK_1811 ENOG4105FGM Fructosamine kinase YPK_1812 ENOG4105CC5 ABC transporter YPK_1813 ENOG4105CC5 ABC transporter YPK_1814 ENOG4105DIK (ABC) transporter YPK_1815 ENOG4105DSE periplasmic solute binding protein YPK_1819 ENOG41087WU YPK_1826 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) YPK_1829 ENOG4108V06 Glutathione peroxidase YPK_1830 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) YPK_1838 ENOG4108QBX (LipO)protein YPK_1841 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) YPK_1843 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) YPK_1844 ENOG4105IPI Membrane YPK_1845 ENOG4105CQB FAD linked oxidase domain protein YPK_1846 ENOG4105KA0 thioesterase Superfamily protein YPK_1847 ENOG4108Z4V iron-sulfur cluster assembly YPK_1848 ENOG4105DIW FeS assembly protein SUFB YPK_1849 ENOG4105C3K feS assembly ATPase SufC YPK_1850 ENOG4105JRK feS assembly protein SufD YPK_1853 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein YPK_1854 ENOG4105KMX major outer membrane lipoprotein YPK_1855 ENOG4105CA9 Pyruvate kinase YPK_1857 ENOG4108R6K riboflavin synthase, subunit alpha YPK_1858 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase YPK_1859 ENOG4105CZQ inner membrane transport protein YdhC YPK_1860 ENOG4105F52 Transcriptional regulator YPK_1863 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) YPK_1864 ENOG4105K4H Nlp p60 protein YPK_1866 ENOG4105M2J Glutaredoxin YPK_1869 ENOG4108UYE Lactoylglutathione lyase YPK_1871 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase YPK_1872 ENOG4108WUH Transcriptional regulator, TetR family YPK_1873 ENOG4105DIJ Phosphoethanolamine transferase YPK_1874 ENOG4105XZD Fe-S protein YPK_1875 ENOG4107RGM aldo keto reductase YPK_1877 ENOG4108XTF Outer Membrane Lipoprotein YPK_1879 ENOG410642K Lysozyme inhibitor YPK_1883 ENOG4108K3A Glutathione S-transferase YPK_1884 ENOG4108ZR5 Conserved Protein YPK_1885 ENOG41069YE inner membrane protein yohC YPK_1886 ENOG4105DUX Transporter YPK_1887 ENOG4105Q4T oxidoreductase YPK_1888 ENOG4108JQ2 peptide transport system atp-binding protein YPK_1889 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein YPK_1890 ENOG4108EU3 peptide transport system, permease YPK_1891 ENOG4108I5W peptide transport system, permease protein YPK_1892 ENOG4108HIY periplasmic YPK_1893 ENOG4105E51 psp operon transcriptional activator YPK_1894 ENOG41087YS Phage shock protein A YPK_1895 ENOG4105YYT phage shock protein B YPK_1896 ENOG4105FM1 phage shock protein C YPK_1898 ENOG4105CM6 amino acid regulated cytosolic protein YPK_1903 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) YPK_1904 ENOG4107S8C mandelate racemase muconate lactonizing YPK_1905 ENOG4105KXI murein peptide amidase A YPK_1906 ENOG4107QSI ABC, transporter YPK_1913 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) YPK_1915 ENOG4105KT7 mgtC SapB transporter YPK_1917 ENOG41090X5 Heat shock protein hslJ YPK_1918 ENOG4105C5I Dehydrogenase YPK_1919 ENOG4107H52 Dicarboxylate transport YPK_1920 ENOG410689M (LipO)protein YPK_1921 ENOG4105WXT Conserved Protein YPK_1922 ENOG4105DEI Mannitol dehydrogenase YPK_1923 ENOG4105DKT Transcriptional regulator YPK_1925 ENOG4105CQ7 ATP-dependent helicase YPK_1928 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap YPK_1930 ENOG4105DS1 cytochrome b561 YPK_1935 ENOG4105CTD carboxy-peptidase YPK_1936 ENOG4105JJR Histidine kinase YPK_1937 ENOG4107EXC regulatoR YPK_1939 ENOG4105D5Q Arginine ornithine antiporter YPK_1940 ENOG4105C5D exported protein YPK_1941 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) YPK_1942 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) YPK_1943 ENOG4105Q9Y Universal stress protein YPK_1944 ENOG4105DS0 Transcriptional regulator, Crp Fnr family YPK_1945 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) YPK_1948 ENOG4105PAD Hydrolase YPK_1949 ENOG4105M71 acetolactate synthase 1 regulatory subunit YPK_1950 ENOG4105C7K acetolactate synthase YPK_1955 ENOG4105FYV Amp nucleosidase YPK_1957 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component YPK_1958 ENOG4107UWC ABC, transporter YPK_1961 ENOG4105C2J ABC transporter YPK_1962 ENOG4105CNN ABC, transporter YPK_1963 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPK_1965 ENOG41060NJ transcriptional regulator YPK_1967 ENOG4105DFD Na H antiporter YPK_1968 ENOG4105C87 Aminotransferase class I and II YPK_1970 ENOG4105D13 transposase YPK_1972 ENOG4105DWP Membrane YPK_1974 ENOG4105C26 Dehydrogenase YPK_1975 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family YPK_1976 ENOG4105EMU Dehydrogenase YPK_1978 ENOG4105KBG Protein of unknown function (DUF1161) YPK_1980 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) YPK_1981 ENOG4105DAG ROK family YPK_1982 ENOG4106NZI LysR family Transcriptional regulator YPK_1983 ENOG4105D94 Major Facilitator Superfamily YPK_1985 ENOG4105C9Q fumarate hydratase class II YPK_1986 ENOG4105EIP mannose-6-phosphate isomerase YPK_1987 ENOG4106J39 exported protein YPK_1988 ENOG4105FDP GntR family transcriptional regulator YPK_1989 ENOG4105CI1 PTS System YPK_1994 ENOG4105DHU Bile acid YPK_1995 ENOG4105D9R oxidoreductase YPK_1997 ENOG4105CNN ABC, transporter YPK_1999 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator YPK_2002 ENOG4108JJA ABC, transporter YPK_2004 ENOG4108JJA ABC, transporter YPK_2005 ENOG4105M9B inner membrane protein ydgK YPK_2009 ENOG4105UEI Transcriptional Regulator AraC Family YPK_2011 ENOG4108UQQ Electron transport complex YPK_2013 ENOG4105CSM endonuclease III YPK_2014 ENOG4105EXW epimerase dehydratase YPK_2015 ENOG4105CSP Major Facilitator Superfamily YPK_2017 ENOG4105D22 carbon starvation protein YPK_2018 ENOG4105VCD cytoplasmic protein YPK_2019 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) YPK_2021 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase YPK_2022 ENOG41061RM osmotically inducible lipoprotein YPK_2023 ENOG4108ZJT translation initiation factor, Sui1 YPK_2026 ENOG4105CFV Tetratricopeptide repeat protein YPK_2027 ENOG4105Q4A inner membrane protein yciS YPK_2028 ENOG4105EYK Phosphatidylglycerophosphatase B YPK_2029 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) YPK_2030 ENOG4107QM5 aconitate hydratase YPK_2032 ENOG4107R11 Transcriptional regulator YPK_2033 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) YPK_2035 ENOG4105RKX Protein of unknown function (DUF2498) YPK_2036 ENOG4105ERU peptidase YPK_2037 ENOG4105UBK short-chain dehydrogenase reductase YPK_2038 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase YPK_2039 ENOG4105FE9 pseudouridine synthase YPK_2040 ENOG4107RTD sua5 ycio yrdc ywlc family protein YPK_2041 ENOG4105DB7 PHP domain protein YPK_2043 ENOG4105DDQ anthranilate synthase YPK_2045 ENOG4105DK0 Indole-3-glycerol phosphate synthase YPK_2049 ENOG4105EIF outer membrane protein W YPK_2054 ENOG4105NAU thioesterase Superfamily protein YPK_2055 ENOG410822N TonB family YPK_2057 ENOG4105K9H YciI-like protein YPK_2061 ENOG4108T1M outer membrane protein x YPK_2066 ENOG4108JQ7 (ABC) transporter YPK_2067 ENOG4105C3U ABC transporter YPK_2068 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPK_2070 ENOG4107QSI ABC, transporter YPK_2071 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein YPK_2072 ENOG4108EKI Dehydrogenase YPK_2073 ENOG4107104 thymidine kinase YPK_2077 ENOG4105C6Y Udp-glucose 6-dehydrogenase YPK_2078 ENOG4105I93 response regulator YPK_2080 ENOG4105CIY formyltetrahydrofolate deformylase YPK_2083 ENOG4105SKE transcriptional Regulator LysR family YPK_2085 ENOG4105CGK Exodeoxyribonuclease III YPK_2086 ENOG4105M6F mutator MutT protein YPK_2087 ENOG4105MTM Protein of unknown function (DUF1496) YPK_2088 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) YPK_2090 ENOG41069NU Nitroreductase YPK_2091 ENOG4105D07 Signal peptide peptidase, SppA YPK_2092 ENOG4105HDK L-asparaginase YPK_2093 ENOG4108RWI nicotinamidase YPK_2094 ENOG4105VUT cytoplasmic protein YPK_2097 ENOG4105DSB aldose 1-epimerase YPK_2098 ENOG4105GNX MltA-interacting MipA family protein YPK_2100 ENOG4105CYN Serine protein kinase YPK_2104 ENOG4105HEI LysR family (Transcriptional regulator YPK_2105 ENOG4105EUB pirin domain protein YPK_2106 ENOG4105CNH Multidrug resistance protein MdtL YPK_2108 ENOG4105ED1 spovr family YPK_2115 ENOG4105C3J Cysteine desulfurase YPK_2118 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase YPK_2119 ENOG4105CVE Lytic murein transglycosylase YPK_2122 ENOG4107QMS site-determining protein YPK_2123 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) YPK_2124 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) YPK_2125 ENOG4105CEY Amp-dependent synthetase and ligase YPK_2126 ENOG4105Y4Z Outer Membrane Lipoprotein YPK_2127 ENOG41072GX Peptidase M22 Glycoprotease YPK_2128 ENOG4105DVT helicase YPK_2129 ENOG4105M4H endoribonuclease L-psp YPK_2132 ENOG4108UHU Aldolase YPK_2134 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase YPK_2135 ENOG4106KNT transcriptional regulator YPK_2136 ENOG4105CA9 Pyruvate kinase YPK_2138 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase YPK_2139 ENOG4105DR5 peptidase YPK_2140 ENOG4105NXV High-affinity zinc uptake system protein YPK_2142 ENOG4105FAV ABC, transporter YPK_2147 ENOG4108TIT dATP pyrophosphohydrolase YPK_2149 ENOG41081XQ Conserved Protein YPK_2150 ENOG4105WJG Glutathione YPK_2154 ENOG4106ZCM YecM protein YPK_2158 ENOG4105CJR Integral membrane protein (MviN YPK_2161 ENOG4105D9U N-acetyltransferase YPK_2163 ENOG4105F3T (LipO)protein YPK_2164 ENOG4107XHZ cytoplasmic chaperone TorD family protein YPK_2166 ENOG4105E2R ROK family YPK_2167 ENOG4108QXE glycerophosphoryl diester phosphodiesterase YPK_2169 ENOG4105F38 ABC transporter, permease YPK_2170 ENOG4105EG2 ABC transporter, permease YPK_2174 ENOG4105CHH sulfate transporter YPK_2176 ENOG41063JG Transcriptional regulator YPK_2177 ENOG4108YY7 Invasion gene expression up-regulator SirB YPK_2178 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) YPK_2184 ENOG4105C5T Phosphoribosyl pyrophosphate synthase YPK_2185 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria YPK_2187 ENOG4105C3G gtp-binding protein YPK_2191 ENOG4105ENX hydrolase YPK_2193 ENOG4105GR3 Histidine kinase YPK_2203 ENOG4108WF3 methyltransferase YPK_2216 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase YPK_2217 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) YPK_2219 ENOG41090B9 response to stress YPK_2220 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) YPK_2221 ENOG4105CZE histidine utilization repressor YPK_2231 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family YPK_2232 ENOG4105BZU Histidine kinase YPK_2233 ENOG4105EWV Sodium calcium exchanger membrane region YPK_2234 ENOG4108RS6 transposase YPK_2235 ENOG4105D5M phosphate starvation-inducible protein YPK_2238 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD YPK_2239 ENOG4105CND Glycosyl transferase, family 2 YPK_2240 ENOG4107BJW polysaccharide deacetylase YPK_2241 ENOG4108TUY outer membrane protein PgaA YPK_2242 ENOG4105H1N peptidase, M24 YPK_2246 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) YPK_2248 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) YPK_2252 ENOG4107SJW iron permease, FTR1 YPK_2254 ENOG4105CSV Glutaminase YPK_2255 ENOG4105MVE transcriptional regulator YPK_2256 ENOG4105C85 amino acid YPK_2257 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family YPK_2258 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPK_2267 ENOG4105DJG MaoC domain protein dehydratase YPK_2268 ENOG4105CYC Transferase YPK_2269 ENOG4108Q9V regulatoR YPK_2274 ENOG4105CW0 outer membrane usher protein YPK_2276 ENOG4108MQF Chaperone YPK_2277 ENOG4108IJ9 (ABC) transporter YPK_2278 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component YPK_2281 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) YPK_2284 ENOG4105FDP GntR family transcriptional regulator YPK_2306 ENOG4105ZTC transcriptional activator, Ogr delta YPK_2307 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) YPK_2319 ENOG4108IRC dna polymerase iii YPK_2320 ENOG4105DFE Dna adenine methylase YPK_2322 ENOG4105VZ1 Replication Protein YPK_2325 ENOG4105ED4 portal protein YPK_2353 ENOG4105ZTC transcriptional activator, Ogr delta YPK_2356 ENOG4105WH1 Two component transcriptional regulator luxr family YPK_2357 ENOG4105XVG cytoplasmic protein YPK_2358 ENOG4105RA2 Membrane YPK_2360 ENOG4108T1M outer membrane protein x YPK_2361 ENOG4105C85 amino acid YPK_2367 ENOG4105CK7 Sodium proline symporter YPK_2369 ENOG4105C26 Dehydrogenase YPK_2374 ENOG4105CDA abc transporter atp-binding protein YPK_2375 ENOG4105E5Q amino acid AbC transporter YPK_2376 ENOG4105EAB amino acid AbC transporter YPK_2378 ENOG4108M9K flagella biosynthesis protein FliZ YPK_2380 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPK_2381 ENOG4105I03 Flagellin YPK_2382 ENOG4105DTS flagellar hook-associated YPK_2383 ENOG4105MQ3 flagellar protein FliS YPK_2386 ENOG4105DHT Metal Dependent Phosphohydrolase YPK_2390 ENOG4105VQ0 flagellar hook-basal body complex protein fliE YPK_2391 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) YPK_2392 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) YPK_2393 ENOG41090PJ Flagellar assembly protein YPK_2394 ENOG4108JIR Flagellum-specific ATP synthase YPK_2395 ENOG4105GSA Flagellar export protein flij YPK_2396 ENOG4105WF4 Flagellar hook-length control protein YPK_2398 ENOG4107ZI8 flagellar basal body-associated protein flil YPK_2399 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) YPK_2400 ENOG4105DD5 Flagellar motor switch protein YPK_2402 ENOG4105CN7 Flagellar biosynthetic protein FliP YPK_2403 ENOG4105VS8 Flagellar biosynthetic protein fliq YPK_2404 ENOG4105D19 Role in flagellar biosynthesis (By similarity) YPK_2407 ENOG4108MGF sugar kinase YPK_2408 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane YPK_2409 ENOG4105C2J ABC transporter YPK_2411 ENOG4105CNN ABC, transporter YPK_2414 ENOG4105DKT Transcriptional regulator YPK_2415 ENOG4105DTJ flagellar hook-associated protein YPK_2416 ENOG4105E1Q flagellar hook-associated protein YPK_2417 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj YPK_2420 ENOG4105CGA flagellar basal-body rod protein FlgG YPK_2421 ENOG4108KPB Flagellar basal-body rod protein FlgF YPK_2422 ENOG4105BZE flagellar hook protein, FlgE YPK_2423 ENOG4105W00 Flagellar hook capping protein YPK_2424 ENOG4108ZC9 flagellar basal-body rod protein flgc YPK_2425 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) YPK_2426 ENOG4105CKS Flagella basal body P-ring formation protein flgA YPK_2427 ENOG4105M9M anti-sigma28 factor FlgM YPK_2428 ENOG4105QVD Flagella synthesis protein FlgN YPK_2430 ENOG4105W13 flagellar protein YPK_2431 ENOG4105D7B Flagellar biosynthesis protein flha YPK_2432 ENOG4105D00 flagellar biosynthetic protein flhB YPK_2435 ENOG4105NKT exported protein YPK_2437 ENOG4105FXM Copper resistance protein YPK_2438 ENOG41090A1 ferritin YPK_2439 ENOG4105MPK DNA polymerase III subunit theta YPK_2442 ENOG4105CUG Oligopeptidase b YPK_2445 ENOG4105X2V dna damage-inducible protein YPK_2446 ENOG4105C1J atp-dependent rna helicase YPK_2449 ENOG4105CRQ synthase (Component I) YPK_2451 ENOG4105EJQ L-serine dehydratase YPK_2452 ENOG4107UWN reductase YPK_2453 ENOG4105EFA 4-hydroxyphenylacetate YPK_2458 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase YPK_2459 ENOG4105C26 Dehydrogenase YPK_2462 ENOG4108V8F Transcriptional regulator, MarR family YPK_2463 ENOG4105EE5 Membrane protein terC YPK_2464 ENOG4108EQA pts system YPK_2465 ENOG4105ETZ PTS System YPK_2466 ENOG4105F3R pts system mannose fructose sorbose family iid YPK_2470 ENOG4105BZU Histidine kinase YPK_2472 ENOG4105DHI Methyltransferase YPK_2473 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase YPK_2474 ENOG4105VEQ Cold shock protein YPK_2475 ENOG410610J Protein of unknown function (DUF2627) YPK_2477 ENOG4105C85 amino acid YPK_2480 ENOG41064PC YPK_2481 ENOG4105TIK YPK_2482 ENOG4105N4N Protein of unknown function (DUF2766) YPK_2487 ENOG4105BZ1 (ABC) transporter YPK_2492 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) YPK_2495 ENOG4108TSE Transferase YPK_2496 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit YPK_2498 ENOG4105CG6 trap dicarboxylate transporter dctm subunit YPK_2499 ENOG4108KX4 response regulator YPK_2500 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme YPK_2504 ENOG4105UQX Mate efflux family protein YPK_2508 ENOG4105DIA mandelate racemase muconate lactonizing YPK_2510 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr YPK_2511 ENOG4105KIR Thiol-disulfide oxidoreductase dcc YPK_2512 ENOG4105CSP Major Facilitator Superfamily YPK_2513 ENOG4105TNG K13735 adhesin invasin YPK_2516 ENOG4105CJB Exodeoxyribonuclease I YPK_2517 ENOG4105CUB amino acid YPK_2519 ENOG4107SCQ Iron-containing alcohol dehydrogenase YPK_2520 ENOG4105C2J ABC transporter YPK_2521 ENOG4105CNN ABC, transporter YPK_2524 ENOG4108535 NAD dependent epimerase/dehydratase family YPK_2526 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) YPK_2529 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) YPK_2532 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase YPK_2533 ENOG4108RS6 transposase YPK_2535 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) YPK_2536 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase YPK_2537 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase YPK_2538 ENOG4105DUU IucA IucC family protein YPK_2539 ENOG4105CNM Receptor YPK_2540 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) YPK_2541 ENOG4105DQ5 transport system permease protein YPK_2542 ENOG4105TVJ transport system, permease YPK_2543 ENOG4105E0A ABC, transporter YPK_2544 ENOG4105DUU IucA IucC family protein YPK_2546 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) YPK_2547 ENOG4105DY8 decarboxylase YPK_2548 ENOG4108819 ferric iron reductase YPK_2549 ENOG4105EE5 Membrane protein terC YPK_2550 ENOG4108GAE asmA family YPK_2553 ENOG4105D1F ATP-binding protein YPK_2558 ENOG4105E5W Transporter YPK_2560 ENOG41067MG lrgb family YPK_2563 ENOG4107GZ4 SanA protein YPK_2564 ENOG4108HWV )-transporter YPK_2567 ENOG4105DHF Membrane YPK_2569 ENOG4105CBP Major Facilitator YPK_2570 ENOG4105EGI Transcriptional regulator YPK_2575 ENOG4105ENT Efflux transporter rnd family, mfp subunit YPK_2576 ENOG4105C19 ABC transporter YPK_2578 ENOG4105CVM Molybdenum cofactor synthesis domain protein YPK_2579 ENOG4105D06 uba thif-type nad fad binding protein YPK_2581 ENOG4105C5H ABC transporter YPK_2602 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase YPK_2603 ENOG41062T2 Acyl carrier protein YPK_2605 ENOG4105CHR reductase YPK_2606 ENOG4108KQ6 Enoyl-CoA hydratase YPK_2608 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase YPK_2609 ENOG4105CHR reductase YPK_2610 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPK_2611 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) YPK_2616 ENOG4108BUD transposase YPK_2618 ENOG4108Z0T Part of a sulfur-relay system (By similarity) YPK_2622 ENOG4105K4P CoA-binding domain protein YPK_2623 ENOG4108Q67 UPF0319 protein YPK_2625 ENOG41088T4 Helicase IV YPK_2626 ENOG410901E Membrane YPK_2627 ENOG4105EM2 membrane YPK_2628 ENOG4108RZ1 DNA transformation protein YPK_2630 ENOG4105UYK outer membrane protein a YPK_2631 ENOG4108RS6 transposase YPK_2633 ENOG4105DAN ATP-dependent protease YPK_2636 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) YPK_2637 ENOG4108Q2G (LipO)protein YPK_2638 ENOG4105DY2 Paraquat-inducible protein b YPK_2639 ENOG4105F1S paraquat-inducible protein a YPK_2640 ENOG4105C5H ABC transporter YPK_2642 ENOG4105QVC MOSC domain-containing protein YPK_2643 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) YPK_2645 ENOG4105CD8 aminopeptidase N YPK_2650 ENOG4105CGF Aromatic amino acid aminotransferase YPK_2652 ENOG4105C5X domain protein YPK_2653 ENOG4105EAQ (twin-arginine translocation) pathway signal YPK_2654 ENOG4105DIT ErfK YbiS YcfS YnhG family protein YPK_2656 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) YPK_2657 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) YPK_2658 ENOG4106371 Methyltransferase YPK_2659 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups YPK_2661 ENOG4105W49 UPF0434 protein YPK_2662 ENOG4105VEQ Cold shock protein YPK_2663 ENOG4105E32 cytoplasmic protein YPK_2666 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 YPK_2668 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) YPK_2674 ENOG4105HDK L-asparaginase YPK_2675 ENOG4105DDY UPF0142 protein ycaO YPK_2676 ENOG4105TMB Formate nitrite transporter YPK_2677 ENOG4105C6N Formate acetyltransferase YPK_2679 ENOG4105F1A Pyruvate formate-lyase YPK_2683 ENOG4105D1H recombination factor protein RarA YPK_2685 ENOG4105CNU cell division protein FtsK YPK_2686 ENOG4105EW9 transcriptional regulator AsnC family YPK_2687 ENOG4105C3M thioredoxin reductase YPK_2688 ENOG4108JJ9 ABC, transporter YPK_2689 ENOG4108JJ8 (ABC) transporter YPK_2691 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) YPK_2692 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPK_2694 ENOG4105VEQ Cold shock protein YPK_2696 ENOG4105DJY efflux transporter, rnd family, mfp subunit YPK_2697 ENOG4108MJ5 VirK protein YPK_2699 ENOG4105CPB ATP-dependent endonuclease of the OLD family YPK_2700 ENOG4105DWU Membrane YPK_2702 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) YPK_2703 ENOG4105C7K acetolactate synthase YPK_2705 ENOG4105C5W Aldolase YPK_2706 ENOG4105CGD Nad-dependent epimerase dehydratase YPK_2707 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase YPK_2708 ENOG41064MM (LipO)protein YPK_2709 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) YPK_2710 ENOG4105E5Z arginine transporter ATP-binding subunit YPK_2711 ENOG4106PMH Extracellular solute-binding protein family 3 YPK_2712 ENOG4105GBT ABC transporter YPK_2713 ENOG4105DMR ABC, transporter YPK_2715 ENOG4108I0N Transporter, RarD family, DMT superfamily protein YPK_2716 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) YPK_2717 ENOG410642S Nicotianamine synthase protein YPK_2718 ENOG4105E0A ABC, transporter YPK_2719 ENOG4108I9K permease protein YPK_2724 ENOG4106TNF Periplasmic binding protein YPK_2726 ENOG4105RBQ inner membrane protein ybjO YPK_2727 ENOG4105D38 putrescine abc transporter YPK_2728 ENOG4105F38 ABC transporter, permease YPK_2729 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) YPK_2730 ENOG4107RUE extracellular solute-binding protein family 1 YPK_2731 ENOG4108RMJ sensory transduction regulator YPK_2732 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress YPK_2733 ENOG41090BQ Glutaredoxin YPK_2734 ENOG4105D0C transport protein YPK_2736 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase YPK_2737 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) YPK_2738 ENOG4107FB0 transcriptional regulator DeoR family YPK_2739 ENOG4105C44 Serine transporter YPK_2740 ENOG4105DZ1 carboxypeptidase YPK_2741 ENOG4108UMI ABC transporter, permease YPK_2743 ENOG4105D01 (LipO)protein YPK_2747 ENOG4108TGY Glutathione S-transferase YPK_2748 ENOG4105D05 Receptor YPK_2750 ENOG4105EHG Permease protein YPK_2752 ENOG4108IQI permease YPK_2754 ENOG4105DUM transcriptional regulator, lysR family YPK_2755 ENOG4105HMI Membrane YPK_2757 ENOG4108D1K outer membrane usher protein YPK_2758 ENOG4108UIF Chaperone YPK_2761 ENOG4108SGD regulatory protein YPK_2762 ENOG4105DM4 PTS System YPK_2763 ENOG4105DE4 1-phosphofructokinase YPK_2764 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein YPK_2766 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane YPK_2767 ENOG4105C2J ABC transporter YPK_2769 ENOG4105E66 phosphoriboisomerase A YPK_2771 ENOG4105C26 Dehydrogenase YPK_2774 ENOG4105CHR reductase YPK_2775 ENOG4105KRS Proteinase inhibitor YPK_2778 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) YPK_2779 ENOG4105DEI Mannitol dehydrogenase YPK_2780 ENOG4107YCY Transcriptional regulator YPK_2782 ENOG4105CKI cobalamin synthesis protein YPK_2783 ENOG41076MN Phosphoesterase, PA-phosphatase related YPK_2784 ENOG4107TT5 NLP P60 protein YPK_2785 ENOG4105CXC rtn protein YPK_2786 ENOG4105E43 Extracellular solute-binding protein, family 5 YPK_2787 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component YPK_2788 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component YPK_2789 ENOG4108JQ5 ABC transporter YPK_2790 ENOG4105HG6 YPK_2792 ENOG4105C2C drug resistance transporter, Bcr CflA YPK_2793 ENOG4105I08 Pseudouridine synthase YPK_2794 ENOG4105CFI type iii restriction protein res subunit YPK_2797 ENOG4105PAN UPF0352 protein YPK_2798 ENOG4105E68 Sulfatase YPK_2800 ENOG4105GMB type VI secretion system effector, hcp1 family YPK_2805 ENOG4105CS2 ec 3.2.1.21 YPK_2807 ENOG4108Q3X Transcriptional regulator YPK_2811 ENOG4108T86 baseplate J family protein YPK_2819 ENOG4105TKZ Tail Sheath YPK_2823 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) YPK_2824 ENOG4105MVE transcriptional regulator YPK_2826 ENOG4105G63 Type III effector Hrp-dependent YPK_2827 ENOG4105HRS Antitermination protein YPK_2830 ENOG4105Y50 Virulence Protein YPK_2833 ENOG4105C8Q Methyl-accepting chemotaxis YPK_2835 ENOG4105CT4 transporter YPK_2836 ENOG4107R6D beta-lactam binding protein AmpH YPK_2839 ENOG4105FCK Membrane YPK_2841 ENOG4106UW1 Major Facilitator superfamily YPK_2842 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC YPK_2843 ENOG41068CG regulatoR YPK_2844 ENOG4105BZU Histidine kinase YPK_2846 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) YPK_2848 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) YPK_2849 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) YPK_2850 ENOG4105XPH Ferredoxin YPK_2853 ENOG4105E0U tyrosine-specific transport protein YPK_2854 ENOG4108UII YfaZ family YPK_2855 ENOG4105CH6 catalase YPK_2856 ENOG4105DVT helicase YPK_2858 ENOG4105FDR Membrane YPK_2860 ENOG4105CXN decarboxylase YPK_2861 ENOG4105D5Q Arginine ornithine antiporter YPK_2862 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component YPK_2863 ENOG4108IJ8 ABC transporter YPK_2864 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component YPK_2865 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system YPK_2866 ENOG4105KHC sulfurtransferase YPK_2869 ENOG4108IV0 ABC, transporter YPK_2870 ENOG4108JJB ABC transporter YPK_2871 ENOG4105CNN ABC, transporter YPK_2872 ENOG4105C32 Amino acid ABC transporter (Permease) YPK_2874 ENOG4108W15 Protein of unknown function (DUF1456) YPK_2877 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein YPK_2879 ENOG4105Y3U Transglycosylase-associated protein YPK_2881 ENOG4105N1F Hnh endonuclease YPK_2884 ENOG4105CXG d-lactate dehydrogenase YPK_2885 ENOG41061WM D-Alanyl-D-Alanine YPK_2887 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) YPK_2889 ENOG4108RS6 transposase YPK_2891 ENOG4105C1J atp-dependent rna helicase YPK_2898 ENOG4105C1J atp-dependent rna helicase YPK_2899 ENOG4107MVR Transcriptional regulator YPK_2901 ENOG4105CJ1 ABC, transporter YPK_2902 ENOG4107QWP ABC-2 type transporter YPK_2903 ENOG4107QWP ABC-2 type transporter YPK_2906 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase YPK_2908 ENOG4105BZU Histidine kinase YPK_2910 ENOG4105EAA nucleoside YPK_2911 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) YPK_2913 ENOG4105CN8 Transcriptional regulator YPK_2914 ENOG4105C94 Transporter YPK_2918 ENOG4105HFZ Membrane YPK_2919 ENOG4108ZAF Molybdopterin YPK_2920 ENOG4105M00 molybdopterin converting factor, subunit 1 YPK_2922 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) YPK_2924 ENOG4105CHW UPF0052 protein YPK_2925 ENOG4105VYA Uncharacterized conserved protein (DUF2132) YPK_2927 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) YPK_2928 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) YPK_2929 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) YPK_2934 ENOG4108K4B hydrolase YPK_2936 ENOG4105E0C molybdate abc transporter YPK_2937 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein YPK_2938 ENOG410680R Protein of unknown function (DUF2592) YPK_2939 ENOG4105F4R Transcriptional regulator mode YPK_2940 ENOG4105DKW ABC transporter YPK_2943 ENOG4105CMR udp-glucose 4-epimerase YPK_2944 ENOG4105F0Z galactose-1-phosphate uridylyltransferase YPK_2946 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) YPK_2949 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) YPK_2951 ENOG4105PGM cation diffusion facilitator family transporter YPK_2952 ENOG4106Z1T Nicotinamide Mononucleotide Transporter YPK_2954 ENOG4105UFD tol-pal system protein YbgF YPK_2955 ENOG4105KCK Peptidoglycan-associated lipoprotein YPK_2957 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA YPK_2957 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA YPK_2958 ENOG4105M8F Biopolymer transport protein exbD tolR YPK_2959 ENOG4105E02 MotA TolQ exbB proton channel YPK_2960 ENOG4107YD3 Thioesterase YPK_2961 ENOG4105KJB cyd operon protein YbgE YPK_2963 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii YPK_2964 ENOG4105C4M (Ubiquinol oxidase) subunit I YPK_2965 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha YPK_2967 ENOG4105C7S Dehydrogenase YPK_2968 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 YPK_2969 ENOG4105E33 succinate dehydrogenase YPK_2971 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein YPK_2972 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit YPK_2973 ENOG4105BZN citrate synthase YPK_2975 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) YPK_2976 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) YPK_2977 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) YPK_2979 ENOG4108Z1B Cyclase dehydrase YPK_2981 ENOG4105DFP Integrase YPK_2986 ENOG4105EV9 Alpha Beta Hydrolase YPK_2989 ENOG4105NNH LexA regulated protein YPK_2990 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) YPK_2991 ENOG41090R7 Ferric uptake YPK_2995 ENOG4108RS6 transposase YPK_2996 ENOG4105CI1 PTS System YPK_2998 ENOG4105CE4 GlcNAc 6-P deacetylase YPK_2999 ENOG4105E2R ROK family YPK_3000 ENOG4105D4U had-superfamily hydrolase, subfamily iia YPK_3001 ENOG4105CAQ asparagine synthetase YPK_3004 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family YPK_3006 ENOG4105C9A Phoh family YPK_3008 ENOG4108JU5 Magnesium and cobalt efflux protein YPK_3009 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) YPK_3010 ENOG4107RP9 extracellular solute-binding protein, family 3 YPK_3011 ENOG4105EAD ABC transporter YPK_3012 ENOG4105DRP amino acid AbC transporter YPK_3013 ENOG4105CDA abc transporter atp-binding protein YPK_3014 ENOG4107PAI alpha helical protein YPK_3017 ENOG4105DJF DNA polymerase III, delta' subunit YPK_3019 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) YPK_3021 ENOG4105CJN penicillin-binding protein YPK_3022 ENOG4105CNI cell division protein FtsW YPK_3023 ENOG4105K6T rare lipoprotein A YPK_3024 ENOG4105DZ1 carboxypeptidase YPK_3028 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) YPK_3030 ENOG4107Z6W Protein CrcB homolog YPK_3031 ENOG4105VEQ Cold shock protein YPK_3033 ENOG4108N8T regulatoR YPK_3037 ENOG4108JJ7 ABC transporter YPK_3039 ENOG4105DH8 myo-inositol catabolism YPK_3041 ENOG4105EDK PfkB domain protein YPK_3042 ENOG4105CK5 oxidoreductase YPK_3043 ENOG4105CNN ABC, transporter YPK_3044 ENOG4105C2J ABC transporter YPK_3045 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator YPK_3048 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) YPK_3049 ENOG4105C26 Dehydrogenase YPK_3053 ENOG4105DN3 alpha-2-macroglobulin domain protein YPK_3054 ENOG4108JQB penicillin-binding protein 1C YPK_3055 ENOG4105HVQ Regulatory factor of maltose metabolism YPK_3060 ENOG4108WC9 type VI secretion system effector, hcp1 family YPK_3067 ENOG4105EZE Cupin 4 family protein YPK_3069 ENOG4105FE9 pseudouridine synthase YPK_3072 ENOG4107QK4 glycoside hydrolase, family 3 domain protein YPK_3076 ENOG4107SET aldo keto reductase YPK_3077 ENOG4105EQ2 LysR family Transcriptional regulator YPK_3080 ENOG41077RS Phosphatase YPK_3081 ENOG4105E8V Alpha Beta Hydrolase Fold protein YPK_3083 ENOG4108HPI phosphatidate Cytidylyltransferase YPK_3084 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase YPK_3091 ENOG4105UZW Tail fiber assembly protein YPK_3108 ENOG4105Y50 Virulence Protein YPK_3110 ENOG4105PTU response to oxidative stress YPK_3122 ENOG4105TKZ Tail Sheath YPK_3128 ENOG4108KU3 Integrase YPK_3133 ENOG4108XS9 dna repair protein YPK_3134 ENOG4106H6R UPF0380 protein YPK_3137 ENOG4108MXD gtp-binding protein YPK_3149 ENOG4105DFP Integrase YPK_3151 ENOG4105WQ3 Rna-binding protein YPK_3153 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) YPK_3155 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) YPK_3156 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit YPK_3157 ENOG4105CV6 ABC transporter, permease YPK_3158 ENOG4108I0Y (ABC) transporter YPK_3159 ENOG4108UJV acyl-CoA thioesterase i YPK_3160 ENOG4105E1F short-chain dehydrogenase reductase YPK_3161 ENOG4107QR8 Thioredoxin YPK_3162 ENOG4107QX8 SPFH domain, Band 7 family protein YPK_3163 ENOG4105G5H Membrane YPK_3164 ENOG4108Z6Z Transcriptional regulator YPK_3165 ENOG4105C59 p-type ATPase YPK_3166 ENOG4105MBR gumn family YPK_3167 ENOG4108Z66 YbaK ebsC protein YPK_3172 ENOG4105EU0 Major facilitator Superfamily YPK_3173 ENOG4108RS6 transposase YPK_3174 ENOG4105EU0 Major facilitator Superfamily YPK_3175 ENOG4105CKD glutathione-regulated potassium-efflux system protein YPK_3176 ENOG4107RE1 Inosine-guanosine kinase YPK_3177 ENOG4108QY5 Ferric enterobactin transport protein YPK_3179 ENOG4105DMT epimerase dehydratase YPK_3181 ENOG4105CJT Mannose-1-phosphate guanylyltransferase YPK_3182 ENOG4105C30 Nad-dependent epimerase dehydratase YPK_3183 ENOG4105C0K Gdp-mannose 4,6-dehydratase YPK_3184 ENOG4108TJN glycosyl transferase group 1 YPK_3186 ENOG41081E6 Inherit from COG: Polysaccharide biosynthesis protein YPK_3188 ENOG4108SMP Nad-dependent epimerase dehydratase YPK_3189 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase YPK_3190 ENOG4105FAW cDP-glucose 4,6-dehydratase YPK_3191 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase YPK_3192 ENOG4108EX3 reductase YPK_3198 ENOG4107QMP dna polymerase iii subunits gamma and tau YPK_3203 ENOG4106428 Protein of unknown function (DUF2496) YPK_3204 ENOG4105EGS Mechanosensitive ion channel YPK_3205 ENOG41090EX DsrE family YPK_3206 ENOG4108IG5 Transcriptional regulator YPK_3207 ENOG4105C1P efflux transporter, rnd family, mfp subunit YPK_3208 ENOG4105BZS acriflavin resistance protein YPK_3209 ENOG4108RS6 transposase YPK_3211 ENOG4105YK5 50S ribosomal protein L36 YPK_3213 ENOG4108UKR Biofilm formation regulator YbaJ YPK_3214 ENOG4105KF5 hemolysin expression-modulating protein YPK_3215 ENOG41080UX Methyltransferase YPK_3216 ENOG4108MNP Glycoprotein polysaccharide metabolism YPK_3217 ENOG4105C29 acyl-CoA thioesterase YPK_3219 ENOG4105BZU Histidine kinase YPK_3220 ENOG4108YZA Nitrogen regulatory protein pii YPK_3221 ENOG4105BZ1 (ABC) transporter YPK_3222 ENOG4105BZ1 (ABC) transporter YPK_3223 ENOG4108XM1 transcriptional regulator AsnC family YPK_3224 ENOG4105C6T cysteine synthase YPK_3226 ENOG4108NFA extracellular solute-binding protein YPK_3228 ENOG4108TGP Thioesterase superfamily protein YPK_3229 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein YPK_3230 ENOG4105EIN peptidylprolyl cis-trans isomerase YPK_3231 ENOG4105K70 DNA-binding protein YPK_3232 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) YPK_3237 ENOG4105M85 Bola protein YPK_3238 ENOG4105IEY (LipO)protein YPK_3239 ENOG4105EYM Major Facilitator superfamily YPK_3241 ENOG4105E2S oxidase) subunit II YPK_3242 ENOG4105BZ9 Cytochrome C oxidase, subunit I YPK_3243 ENOG4105CCU oxidase (Subunit III) YPK_3244 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) YPK_3246 ENOG4107RDB Major Facilitator YPK_3248 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) YPK_3249 ENOG4107S0N DJ-1 family YPK_3252 ENOG4105CTB Polyprenyl synthetase YPK_3254 ENOG4108ZAI phosphatidylglycerophosphatase a YPK_3255 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) YPK_3258 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) YPK_3261 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) YPK_3262 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) YPK_3263 ENOG4105VIE preprotein translocase, subunit YajC YPK_3267 ENOG4105D3R alkyl hydroperoxide reductase YPK_3270 ENOG4107FW0 short-chain dehydrogenase reductase YPK_3271 ENOG4107R28 alpha amylase, catalytic region YPK_3272 ENOG4105C85 amino acid YPK_3273 ENOG4105CWM branched-chain amino acid transport system II carrier protein YPK_3275 ENOG4105BZU Histidine kinase YPK_3276 ENOG4105CK6 Two component transcriptional regulator (Winged helix family YPK_3277 ENOG4107RH8 nuclease SbcCD subunit D YPK_3278 ENOG4105EYH Exonuclease YPK_3279 ENOG4105DKQ ROK family YPK_3284 ENOG4105F2W methyltransferase YPK_3295 ENOG4105CIN aminoacyl-histidine dipeptidase YPK_3299 ENOG4105CJ2 (LipO)protein YPK_3303 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPK_3304 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPK_3305 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) YPK_3306 ENOG4105F7V ErfK ybiS ycfS ynhG family protein YPK_3307 ENOG4105E7A Glutamine amidotransferase YPK_3309 ENOG4107QPN acyl-Coa dehydrogenase YPK_3311 ENOG4106YJS accessory processing protein YPK_3316 ENOG4108RS6 transposase YPK_3322 ENOG4105CHM Aminotransferase YPK_3325 ENOG4105C5R Aminotransferase YPK_3327 ENOG4105E5Q amino acid AbC transporter YPK_3329 ENOG4105F87 Dehydratase YPK_3334 ENOG4105EQ0 Major Facilitator superfamily YPK_3335 ENOG4108UMN azlc family YPK_3336 ENOG4105ZED uncharacterized protein ygaH YPK_3337 ENOG4105NTK Transcriptional repressor Mpra YPK_3338 ENOG4105CW7 secretion protein, HlyD family YPK_3339 ENOG4105C0R drug resistance transporter emrb qaca subfamily YPK_3340 ENOG4105EIB trna rrna methyltransferase YPK_3341 ENOG4105K63 Thioredoxin YPK_3342 ENOG4106IUH DTW domain containing protein YPK_3343 ENOG4105CD5 CoA-binding domain protein YPK_3344 ENOG4105JIM Phosphatidylserine synthase YPK_3345 ENOG4105T42 (LipO)protein YPK_3349 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPK_3350 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase YPK_3351 ENOG4105C34 Pseudouridine synthase YPK_3352 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane YPK_3353 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA YPK_3357 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) YPK_3358 ENOG4108NEV two component transcriptional regulator, LytTR family YPK_3359 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter YPK_3360 ENOG4108NE3 Salt-induced outer membrane protein YPK_3365 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY YPK_3366 ENOG4106KVJ cytochrome C assembly protein YPK_3367 ENOG4108JU6 CBS domain protein YPK_3370 ENOG4105W39 Membrane YPK_3371 ENOG4107VXZ Hydrolase YPK_3372 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) YPK_3381 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) YPK_3382 ENOG4108IUS Transketolase YPK_3383 ENOG4108HHA Transketolase YPK_3384 ENOG4105CNN ABC, transporter YPK_3385 ENOG4105C2J ABC transporter YPK_3389 ENOG4108XVM Cytochrome b(562) YPK_3390 ENOG4105CPW cytochrome b561 YPK_3391 ENOG4108NEM leader-binding protein dmsD YPK_3392 ENOG4107KGK dmso reductase anchor subunit YPK_3393 ENOG4105QAX Iron-sulfur YPK_3394 ENOG4107QY8 reductase YPK_3395 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase YPK_3397 ENOG4105E98 transcriptional regulator DeoR family YPK_3399 ENOG4105C2J ABC transporter YPK_3400 ENOG4105CNN ABC, transporter YPK_3401 ENOG4105F5R ABC transporter YPK_3402 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase YPK_3403 ENOG4105CMG Carbohydrate kinase YPK_3404 ENOG4107GFK fumarate YPK_3406 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) YPK_3409 ENOG4105D05 Receptor YPK_3411 ENOG4105CA0 peroxidase YPK_3412 ENOG4105E89 ABC transporter YPK_3417 ENOG4105DKT Transcriptional regulator YPK_3419 ENOG4105CMT Dihydroxyacetone kinase YPK_3420 ENOG4105CHR reductase YPK_3421 ENOG4105CPQ Dehydrogenase YPK_3422 ENOG4108YZG isomerase YPK_3425 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) YPK_3426 ENOG4108K5P (LipO)protein YPK_3433 ENOG4105N0Z inner membrane protein ygbE YPK_3434 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) YPK_3443 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase YPK_3444 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) YPK_3448 ENOG4105DXN mazG family YPK_3449 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) YPK_3450 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) YPK_3451 ENOG4105BZU Histidine kinase YPK_3452 ENOG4105C0H protease YPK_3456 ENOG4105EN6 Membrane YPK_3460 ENOG4105S6R Iron-hydroxamate transporter permease subunit YPK_3461 ENOG4105J76 Periplasmic binding protein YPK_3462 ENOG4105E0A ABC, transporter YPK_3463 ENOG4105BZ4 penicillin-binding protein YPK_3464 ENOG4105CQ7 ATP-dependent helicase YPK_3466 ENOG4107XID 2'-5' rna ligase YPK_3468 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters YPK_3470 ENOG4105DJ0 Poly(A) Polymerase YPK_3471 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YPK_3475 ENOG4107BJW polysaccharide deacetylase YPK_3476 ENOG4105E3A (ABC) transporter YPK_3477 ENOG4105DA5 (ABC) transporter YPK_3478 ENOG41077A9 carbonic anhydrase YPK_3479 ENOG4108UGV hypoxanthine phosphoribosyltransferase YPK_3480 ENOG4105E3B Multicopper oxidase YPK_3481 ENOG4108ZRK uncharacterized protein yacC YPK_3485 ENOG4105RPH Inner membrane protein YddG YPK_3487 ENOG4107QIJ Aconitate hydratase 2 YPK_3488 ENOG4108RS6 transposase YPK_3489 ENOG4107QN2 dihydrolipoyl dehydrogenase YPK_3490 ENOG4107QSN dihydrolipoamide acetyltransferase YPK_3491 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) YPK_3492 ENOG41073TP transcriptional regulator YPK_3494 ENOG4105C85 amino acid YPK_3495 ENOG4106A72 regulatory protein AmpE YPK_3496 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase YPK_3497 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase YPK_3498 ENOG4108ZUW Major pilin subunit YPK_3499 ENOG4107QHF type ii secretion system protein e YPK_3500 ENOG4105D7Q type ii secretion system YPK_3503 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) YPK_3506 ENOG4108RS6 transposase YPK_3508 ENOG4105M6F mutator MutT protein YPK_3513 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) YPK_3514 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) YPK_3515 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) YPK_3519 ENOG4105CNI cell division protein FtsW YPK_3522 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) YPK_3523 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) YPK_3524 ENOG4105CJN penicillin-binding protein YPK_3525 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) YPK_3528 ENOG4108RNS Exports L-alanine (By similarity) YPK_3529 ENOG4107B7Y DNA-binding transcriptional regulator FruR YPK_3530 ENOG4108ZP8 Acetolactate synthase small subunit YPK_3531 ENOG4105C7K acetolactate synthase YPK_3532 ENOG4108IQE Amp-dependent synthetase and ligase YPK_3533 ENOG41064T2 transcriptional regulator, lysR family YPK_3536 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) YPK_3539 ENOG4105S8Q sugar efflux transporter YPK_3542 ENOG4105DP9 ABC transporter YPK_3543 ENOG4106SMU thiamine transporter membrane protein YPK_3545 ENOG4108KF1 Membrane YPK_3546 ENOG4105CQ2 DNA polymerase YPK_3558 ENOG4105CS6 Rhs element vgr protein YPK_3559 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit YPK_3568 ENOG4105D3G Pseudouridine synthase YPK_3569 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) YPK_3571 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) YPK_3578 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) YPK_3580 ENOG4105DWK Membrane YPK_3581 ENOG4108NIW Leucine export protein LeuE YPK_3582 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain YPK_3583 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain YPK_3586 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase YPK_3589 ENOG4105DTN riboflavin biosynthesis protein ribF YPK_3591 ENOG41063Z6 transcriptional regulator, lysR family YPK_3595 ENOG4106HK8 GPR1 FUN34 yaaH family protein YPK_3598 ENOG4108RIR Molybdenum cofactor biosynthesis protein YPK_3606 ENOG41065U4 response regulator YPK_3607 ENOG4108RH0 Crea protein YPK_3609 ENOG4105UEI Transcriptional Regulator AraC Family YPK_3612 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) YPK_3613 ENOG4107SC1 transglycosylase YPK_3616 ENOG4108KHX Diguanylate cyclase YPK_3617 ENOG41090EK ompa motb domain protein YPK_3618 ENOG4105C5H ABC transporter YPK_3620 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase YPK_3621 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) YPK_3622 ENOG4105EAC phosphoserine phosphatase YPK_3623 ENOG41062Z9 Membrane YPK_3627 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) YPK_3628 ENOG4105D9N nucleoside YPK_3629 ENOG4105EYA deoxyribonuclease YPK_3630 ENOG4108NRW Phospholipase, patatin family YPK_3632 ENOG4105K3G Periplasmic Protein YPK_3634 ENOG4105KEG ribosomal-protein-alanine acetyltransferase YPK_3635 ENOG4108WPU DNA polymerase III subunit psi YPK_3637 ENOG4105YBH Protein of unknown function (DUF1435) YPK_3638 ENOG4105BZU Histidine kinase YPK_3642 ENOG4105BZS acriflavin resistance protein YPK_3643 ENOG410624X efflux transporter, rnd family, mfp subunit YPK_3647 ENOG4105DKP glycosyl transferase, family 9 YPK_3649 ENOG4105DKT Transcriptional regulator YPK_3656 ENOG4105RI1 glycoprotein receptor YPK_3657 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) YPK_3658 ENOG4105DM4 PTS System YPK_3659 ENOG4108YRF PTS System YPK_3660 ENOG4108XCZ PTS System YPK_3661 ENOG4106R3P AraC family transcriptional regulator YPK_3663 ENOG4108M3P Membrane YPK_3666 ENOG4105DZR Type I site-specific deoxyribonuclease YPK_3674 ENOG4105DZR Type I site-specific deoxyribonuclease YPK_3677 ENOG4108K5H permease YjgP YjgQ family protein YPK_3678 ENOG4108M8S permease YjgP YjgQ family protein YPK_3680 ENOG4105MYG DNA polymerase iii, chi subunit YPK_3682 ENOG4108MJ3 acetyltransferase YPK_3683 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) YPK_3685 ENOG4105XEP YhcH YjgK YiaL family protein YPK_3687 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component YPK_3688 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component YPK_3689 ENOG4105C3U ABC transporter YPK_3690 ENOG4108JQ7 (ABC) transporter YPK_3691 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase YPK_3692 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) YPK_3693 ENOG4107RJJ Transcriptional regulator YPK_3694 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG YPK_3695 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH YPK_3696 ENOG4105EKV Phosphonate metabolism protein YPK_3697 ENOG4105FT8 Phosphonate metabolism YPK_3698 ENOG4105ENV phosphonate C-P lyase system protein PhnK YPK_3699 ENOG4105HRV phosphonate c-p lyase system protein phnl YPK_3700 ENOG4105FD8 phosphonate metabolism protein PhnM YPK_3701 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) YPK_3702 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein YPK_3703 ENOG4105K4T epimerase YPK_3707 ENOG4105DRS transport system, permease YPK_3708 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component YPK_3713 ENOG4108YYD acetyltransferase YPK_3714 ENOG4105XPQ lipid carrier protein YPK_3715 ENOG4105CFP Peptidase U32 YPK_3716 ENOG4106RZ4 Peptidase U32 YPK_3717 ENOG4105ENJ RND efflux system, outer membrane lipoprotein YPK_3718 ENOG4105BZS acriflavin resistance protein YPK_3720 ENOG4105DEN Luciferase family YPK_3724 ENOG4105C1J atp-dependent rna helicase YPK_3731 ENOG4105CHV Transcription elongation factor NusA YPK_3735 ENOG4105EEI dihydropteroate synthase YPK_3736 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) YPK_3738 ENOG4105HBR Rna-binding protein YPK_3739 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) YPK_3740 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase YPK_3755 ENOG4105QYV Membrane YPK_3758 ENOG4105EAH synthase YPK_3760 ENOG4105HVQ Regulatory factor of maltose metabolism YPK_3765 ENOG4105DFU Cell wall formation (By similarity) YPK_3767 ENOG4105F0N pyrophosphate phospho-hydrolase YPK_3768 ENOG4108ZHD aig2 family YPK_3769 ENOG4105MA0 exported protein YPK_3770 ENOG4105CFU surface antigen YPK_3772 ENOG4105C37 (CBS) domain YPK_3773 ENOG41061GZ Protein of unknown function (DUF1107) YPK_3774 ENOG4108UUE Transcriptional regulator YPK_3775 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase YPK_3776 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic YPK_3778 ENOG4108V1T peptidylprolyl cis-trans isomerase YPK_3779 ENOG4105FHY Opacity-associated protein A YPK_3782 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) YPK_3784 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) YPK_3786 ENOG4108MXZ Esterase YPK_3787 ENOG4105WSB biofilm stress and motility protein A YPK_3788 ENOG4105CSU acyl-Coa dehydrogenase YPK_3790 ENOG4105C2N RNA methyltransferase TrmH family group 3 YPK_3791 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) YPK_3795 ENOG4105EPW hflc protein YPK_3796 ENOG4107QJR hflk protein YPK_3797 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) YPK_3802 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase YPK_3803 ENOG4105K8N protein family UPF0079, ATPase YPK_3804 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) YPK_3805 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) YPK_3811 ENOG4105EGS Mechanosensitive ion channel YPK_3816 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) YPK_3817 ENOG4105KPY Small multidrug resistance protein YPK_3819 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein YPK_3821 ENOG4108ZVF (LipO)protein YPK_3826 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter YPK_3829 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) YPK_3830 ENOG4108RC0 Electron transport protein YPK_3831 ENOG4105BZ8 glutamate synthase YPK_3832 ENOG4108SIC Transcriptional regulator YPK_3848 ENOG4105C0A alcohol dehydrogenase YPK_3850 ENOG4108UUM single-stranded DNA-binding protein YPK_3851 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) YPK_3852 ENOG4105MSB protein, conserved in bacteria YPK_3853 ENOG4105CGF Aromatic amino acid aminotransferase YPK_3854 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) YPK_3855 ENOG4105CDU Replicative dna helicase YPK_3856 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein YPK_3857 ENOG4105P4Z Phage shock protein G YPK_3858 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) YPK_3859 ENOG4105MYN Zinc uptake regulation protein YPK_3861 ENOG41080IJ Diacylglycerol kinase YPK_3869 ENOG4108S1B Periplasmic chaperone protein YPK_3881 ENOG4105DAX Pfam:DUF2983 YPK_3885 ENOG4105D4P Coproporphyrinogen iii oxidase YPK_3886 ENOG41090JE Utilization Protein YPK_3888 ENOG4107F3C Hemin uptake protein YPK_3889 ENOG4107ENK receptor YPK_3890 ENOG4106QJH hemin transport protein YPK_3891 ENOG4107R4I Periplasmic binding protein YPK_3892 ENOG4105EHG Permease protein YPK_3894 ENOG4105C28 cystathionine YPK_3895 ENOG4105C44 Serine transporter YPK_3896 ENOG4105EQ2 LysR family Transcriptional regulator YPK_3897 ENOG4105KSU Redox protein YPK_3898 ENOG41066VF YeeE YedE family protein YPK_3899 ENOG4108IUF type iii secretion YPK_3900 ENOG4108TN6 type iii secretion YPK_3901 ENOG41083GP type iii secretion YPK_3902 ENOG4108HHI Type III secretion system protein YPK_3906 ENOG4108JIR Flagellum-specific ATP synthase YPK_3918 ENOG4105BZU Histidine kinase YPK_3919 ENOG4105WH1 Two component transcriptional regulator luxr family YPK_3920 ENOG4105CK2 sodium dicarboxylate symporter YPK_3922 ENOG41062QD Membrane YPK_3925 ENOG4105CMM transposase YPK_3929 ENOG4108RR8 protoporphyrinogen oxidase YPK_3930 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) YPK_3931 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein YPK_3935 ENOG4107QK7 reductase YPK_3937 ENOG4105MDZ Transcriptional activator rfaH YPK_3938 ENOG4105D52 delta-aminolevulinic acid dehydratase YPK_3940 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) YPK_3942 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) YPK_3944 ENOG4105JC1 sterol-binding domain protein YPK_3946 ENOG4105CGY Dna recombination protein YPK_3947 ENOG4108KF1 Membrane YPK_3950 ENOG4108I5U Uridine phosphorylase YPK_3951 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) YPK_3953 ENOG4105DZ2 Transcriptional regulator YPK_3954 ENOG4105EMK carboxylate amino acid amine transporter YPK_3957 ENOG4105RK9 auxin efflux carrier YPK_3958 ENOG4107T6V glycerophosphoryl diester phosphodiesterase YPK_3970 ENOG4108IV0 ABC, transporter YPK_3971 ENOG4105C0Z ABC transporter YPK_3972 ENOG4105CF8 branched-chain amino acid ABC transporter, permease YPK_3973 ENOG4105C32 Amino acid ABC transporter (Permease) YPK_3974 ENOG4105CP9 extracellular ligand-binding receptor YPK_3975 ENOG4105U59 -acetyltransferase YPK_3977 ENOG4105CRP Part of the ABC transporter FtsEX involved in YPK_3978 ENOG4105CAK Cell division ATP-binding protein ftsE YPK_3979 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) YPK_3979 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) YPK_3980 ENOG4106H78 methyltransferase YPK_3981 ENOG4105MG3 Membrane YPK_3984 ENOG4107FS9 Membrane YPK_3987 ENOG4105EX9 Membrane YPK_3988 ENOG4108W1V Lipoprotein YPK_3989 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) YPK_3991 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A YPK_3992 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase YPK_3994 ENOG4105DQF Hydrolase YPK_3995 ENOG4108EUD Lysophospholipase YPK_3997 ENOG4105CCF Lysine exporter protein (Lyse ygga) YPK_3998 ENOG4105C9U ATP-dependent DNA helicase RecQ YPK_3999 ENOG4105HDD phospholipase YPK_4000 ENOG4108VUY thioesterase Superfamily protein YPK_4001 ENOG4105FR1 rard protein YPK_4002 ENOG4107QUT magnesium and cobalt transport protein CorA YPK_4005 ENOG4105EQN UPF0261 protein YPK_4007 ENOG4105C4R Atp-dependent dna helicase YPK_4008 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant YPK_4009 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) YPK_4010 ENOG4105CT0 Protein of unknown function, DUF484 YPK_4012 ENOG4105S7Z (LipO)protein YPK_4015 ENOG4107T0K Adenylate cyclase YPK_4017 ENOG41076E6 Uroporphyrinogen-III Synthase YPK_4018 ENOG4105ECF c-methyltransferase YPK_4019 ENOG410601J HemY protein YPK_4021 ENOG4105C85 amino acid YPK_4025 ENOG4105EGZ biosynthesis protein YPK_4026 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase YPK_4027 ENOG4108WJ1 acetyltransferase YPK_4028 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) YPK_4029 ENOG4105C1B dTDP-glucose 4-6-dehydratase YPK_4030 ENOG4108IJ1 Dehydrogenase YPK_4031 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase YPK_4032 ENOG4105SFE lipopolysaccharide biosynthesis protein YPK_4033 ENOG4105ESV Glycosyl transferase, family 4 YPK_4035 ENOG4105K63 Thioredoxin YPK_4038 ENOG4105C4R Atp-dependent dna helicase YPK_4040 ENOG4105KQ5 peptidylprolyl cis-trans isomerase YPK_4043 ENOG4105GQR Chaperone YPK_4044 ENOG4105CW0 outer membrane usher protein YPK_4046 ENOG4108VEV chaperone YPK_4052 ENOG4105EMY transcriptional regulator YPK_4056 ENOG4105C7B Threonine dehydratase YPK_4059 ENOG4105CM2 brancheD-chain amino acid aminotransferase YPK_4060 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit YPK_4062 ENOG4105C0P Mg chelatase subunit ChlI YPK_4063 ENOG4108WFC UPF0438 protein yifE YPK_4065 ENOG41062B0 ABC transporter, permease YPK_4066 ENOG4107R9N ABC transporter YPK_4067 ENOG4105C2J ABC transporter YPK_4068 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator YPK_4075 ENOG4108Y73 Membrane YPK_4079 ENOG4105C5Q Transcriptional regulator YPK_4080 ENOG4105EHV domain protein YPK_4081 ENOG4107QN2 dihydrolipoyl dehydrogenase YPK_4082 ENOG4105YHG TonB family YPK_4083 ENOG4107QZV Type I secretion membrane fusion protein YPK_4086 ENOG4105X58 receptor YPK_4093 ENOG4105SYT Methylenetetrahydrofolate reductase YPK_4094 ENOG4105CFH Aspartokinase YPK_4095 ENOG4105C28 cystathionine YPK_4096 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) YPK_4097 ENOG4108Z12 YiaAB two helix domain-containing protein YPK_4099 ENOG4105C25 Primosomal protein n' YPK_4101 ENOG4105ETE Transcriptional regulator (LacI family YPK_4102 ENOG41063M6 Cell Division Protein YPK_4105 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase YPK_4109 ENOG4108MBX Secretion Protein YPK_4110 ENOG4108JJA ABC, transporter YPK_4112 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) YPK_4113 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) YPK_4114 ENOG4105CBT Fructose-1,6-bisphosphatase YPK_4115 ENOG4105DP0 ferredoxin-NADP reductase YPK_4116 ENOG4108VTS Membrane YPK_4117 ENOG4105EBK exported protein YPK_4119 ENOG4107F9Y LysR family transcriptional regulator YPK_4121 ENOG4105JSC dimethylmenaquinone methyltransferase YPK_4122 ENOG4107QPK )-transporter YPK_4125 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein YPK_4131 ENOG4105FMW periplasmic YPK_4132 ENOG4105E3W Two component transcriptional regulator (Winged helix family YPK_4133 ENOG4105E0F Histidine kinase YPK_4134 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) YPK_4135 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) YPK_4136 ENOG4105D7W serine acetyltransferase YPK_4139 ENOG4105VW4 glutaredoxin 3 YPK_4140 ENOG4107YZP Rhodanese domain protein YPK_4142 ENOG41063SB peptidase YPK_4143 ENOG4105PXI polysaccharide deacetylase YPK_4145 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) YPK_4147 ENOG4105XA0 heptosyltransferase ii YPK_4148 ENOG4105D16 lipopolysaccharide heptosyltransferase i YPK_4149 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase YPK_4153 ENOG4105W0E 50S ribosomal protein L33 YPK_4156 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase YPK_4161 ENOG4105DSJ YicC domain protein YPK_4174 ENOG4105EN6 Membrane YPK_4175 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) YPK_4177 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) YPK_4178 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) YPK_4179 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase YPK_4180 ENOG4105CB5 ATP-dependent DNA helicase recG YPK_4181 ENOG4105D6U Sodium Glutamate Symporter YPK_4182 ENOG4105C2W permease YPK_4183 ENOG4105JV1 AsmA family YPK_4184 ENOG4105SUU thioesterase domain YPK_4187 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 YPK_4189 ENOG4105C5F glutamine synthetase YPK_4190 ENOG4105CUX Signal transduction histidine kinase YPK_4191 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family YPK_4192 ENOG4105D4P Coproporphyrinogen iii oxidase YPK_4195 ENOG4105C2M dna polymerase I YPK_4196 ENOG4108Z33 Thiol disulfide Interchange Protein YPK_4197 ENOG4105E27 serine threonine protein kinase YPK_4198 ENOG4105PC1 Conserved Protein YPK_4200 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b YPK_4206 ENOG4107EJG GntR family transcriptional regulator YPK_4207 ENOG4105C0R drug resistance transporter emrb qaca subfamily YPK_4209 ENOG4108RVA ribokinase YPK_4215 ENOG4108VVK transcriptional Regulator, AsnC YPK_4216 ENOG4105QTB Flavodoxin YPK_4219 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation YPK_4221 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) YPK_4229 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) YPK_4231 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) YPK_4232 ENOG4105C8U phosphate abc transporter YPK_4233 ENOG4105E2Z phosphate ABC transporter (Permease YPK_4237 ENOG4106PMH Extracellular solute-binding protein family 3 YPK_4238 ENOG4105EAD ABC transporter YPK_4239 ENOG4105DRP amino acid AbC transporter YPK_4240 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 YPK_4241 ENOG4105C7N Xanthine uracil vitamin C permease YPK_4246 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins YPK_4249 ENOG4105VG0 50S ribosomal protein l34