locus-tag	class	description
YPK_0002	COG0592	DNA-directed DNA polymerase activity
YPK_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
YPK_0004	COG0187	DNA topoisomerase II activity
YPK_0005	COG0561	phosphatase activity
YPK_0007	COG2423	ornithine cyclodeaminase activity
YPK_0008	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
YPK_0009	COG0823	Involved in the tonB-independent uptake of proteins
YPK_0010	COG5645	(Lipo)protein
YPK_0014	COG3977	Valine--pyruvate aminotransferase
YPK_0016	COG0366	Alpha amylase catalytic
YPK_0019	COG2885	chlorophyll binding
YPK_0021	COG2818	Glycosylase
YPK_0026	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPK_0026	COG2213	PTS system mannitol-specific
YPK_0028	COG3722	fumarate hydratase activity
YPK_0035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPK_0037	COG3383	formate dehydrogenase (NAD+) activity
YPK_0037	COG0243	molybdopterin cofactor binding
YPK_0038	COG0243	molybdopterin cofactor binding
YPK_0038	COG3383	formate dehydrogenase (NAD+) activity
YPK_0039	COG0437	4 iron, 4 sulfur cluster binding
YPK_0040	COG2864	formate dehydrogenase
YPK_0043	COG3276	selenocysteine insertion sequence binding
YPK_0050	COG3274	enterobacterial common antigen metabolic process
YPK_0052	COG3188	usher protein
YPK_0053	COG3121	Chaperone
YPK_0055	COG1070	Carbohydrate kinase
YPK_0057	COG4213	ABC transporter substrate-binding protein
YPK_0059	COG4214	carbohydrate transport
YPK_0060	COG1609	Transcriptional regulator
YPK_0060	COG2207	Transcriptional regulator
YPK_0061	COG0582	viral genome integration into host DNA
YPK_0067	COG2801	Transposase and inactivated derivatives
YPK_0068	COG4604	ABC transporter, ATP-binding protein
YPK_0069	COG4605	iron ion homeostasis
YPK_0071	COG4607	ABC-type enterochelin transport system periplasmic component
YPK_0074	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
YPK_0080	COG2194	sulfuric ester hydrolase activity
YPK_0081	COG2197	response regulator
YPK_0082	COG3851	Histidine kinase
YPK_0083	COG2271	Major facilitator Superfamily
YPK_0086	COG2831	hemolysin activation secretion protein
YPK_0088	COG0747	negative chemotaxis
YPK_0089	COG0601	transmembrane transport
YPK_0090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPK_0091	COG0444	Belongs to the ABC transporter superfamily
YPK_0092	COG4608	Belongs to the ABC transporter superfamily
YPK_0094	COG2200	EAL domain
YPK_0094	COG2199	diguanylate cyclase activity
YPK_0095	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPK_0100	COG0612	Peptidase, M16
YPK_0101	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPK_0102	COG1942	4-Oxalocrotonate Tautomerase
YPK_0103	COG2200	EAL domain
YPK_0104	COG2982	Protein involved in outer membrane biogenesis
YPK_0105	COG2134	cdp-diacylglycerol pyrophosphatase
YPK_0106	COG1295	ribonuclease BN
YPK_0111	COG1929	Belongs to the glycerate kinase type-1 family
YPK_0112	COG2610	gluconate transmembrane transporter activity
YPK_0113	COG3835	regulator
YPK_0114	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPK_0115	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
YPK_0116	COG0339	signal peptide processing
YPK_0120	COG0589	response to stress
YPK_0122	COG0306	phosphate transporter
YPK_0123	COG2081	HI0933 family
YPK_0126	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_0127	COG1879	ABC-type sugar transport system periplasmic component
YPK_0129	COG0191	fructose-bisphosphate aldolase activity
YPK_0131	COG0745	RESPONSE REGULATOR receiver
YPK_0133	COG1741	Belongs to the pirin family
YPK_0134	COG1609	Transcriptional regulator
YPK_0135	COG2610	gluconate transmembrane transporter activity
YPK_0136	COG3265	gluconokinase activity
YPK_0140	COG2095	MarC family integral membrane protein
YPK_0141	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPK_0146	COG3275	phosphorelay sensor kinase activity
YPK_0151	COG0058	SHG alpha-glucan phosphorylase activity
YPK_0152	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPK_0157	COG1349	DNA-binding transcription factor activity
YPK_0161	COG0058	SHG alpha-glucan phosphorylase activity
YPK_0162	COG1640	4-alpha-glucanotransferase
YPK_0169	COG1918	ferrous iron import across plasma membrane
YPK_0170	COG2183	response to ionizing radiation
YPK_0171	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPK_0172	COG0745	RESPONSE REGULATOR receiver
YPK_0176	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
YPK_0177	COG1011	Hydrolase
YPK_0180	COG0494	nUDIX hydrolase
YPK_0183	COG5301	cellulose 1,4-beta-cellobiosidase activity
YPK_0199	COG3179	chitinase
YPK_0202	COG4382	Mu-like prophage protein Gp16
YPK_0217	COG3423	Transcriptional regulator
YPK_0219	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
YPK_0224	COG4796	Type ii and iii secretion system protein
YPK_0229	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
YPK_0230	COG0546	phosphoglycolate phosphatase activity
YPK_0231	COG0180	Tryptophanyl-tRNA synthetase
YPK_0234	COG2146	nitrite reductase [NAD(P)H] activity
YPK_0235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
YPK_0237	COG0402	S-adenosylhomocysteine deaminase activity
YPK_0241	COG1486	melibiose metabolic process
YPK_0242	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPK_0243	COG0433	COG0433 Predicted ATPase
YPK_0247	COG1289	transmembrane transporter activity
YPK_0249	COG1765	OsmC-like protein
YPK_0251	COG3157	Type VI secretion system effector, Hcp
YPK_0254	COG3954	Phosphoribulokinase
YPK_0256	COG0429	hydrolase of the alpha beta-hydrolase fold
YPK_0258	COG4521	taurine ABC transporter
YPK_0260	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPK_0261	COG2175	clavaminate synthase activity
YPK_0263	COG1216	Glycosyl transferase, family 2
YPK_0264	COG0488	(ABC) transporter
YPK_0267	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
YPK_0268	COG1047	Peptidyl-prolyl cis-trans
YPK_0270	COG0545	Peptidyl-prolyl cis-trans isomerase
YPK_0271	COG2964	Protein conserved in bacteria
YPK_0275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
YPK_0276	COG0049	tRNA binding
YPK_0279	COG1943	Transposase
YPK_0282	COG0051	transcription antitermination factor activity, RNA binding
YPK_0287	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
YPK_0289	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
YPK_0290	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
YPK_0292	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
YPK_0293	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
YPK_0301	COG1841	ribosomal large subunit assembly
YPK_0303	COG0201	protein transport
YPK_0304	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPK_0307	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
YPK_0310	COG0789	Transcriptional regulator
YPK_0311	COG3036	rescue of stalled ribosome
YPK_0313	COG0569	domain protein
YPK_0317	COG0758	DNA mediated transformation
YPK_0319	COG0551	DNA topoisomerase type I activity
YPK_0322	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
YPK_0333	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPK_0334	COG0250	Participates in transcription elongation, termination and antitermination
YPK_0345	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
YPK_0347	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
YPK_0352	COG1515	deoxyribonuclease V activity
YPK_0353	COG3068	Protein conserved in bacteria
YPK_0356	COG0151	Belongs to the GarS family
YPK_0364	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
YPK_0365	COG2224	Isocitrate lyase
YPK_0367	COG1414	Transcriptional regulator
YPK_0372	COG0527	aspartate kinase activity
YPK_0376	COG3833	ABC-type maltose transport systems, permease component
YPK_0377	COG1175	transmembrane transport
YPK_0401	COG3501	Rhs element vgr protein
YPK_0403	COG3209	COG3209 Rhs family protein
YPK_0410	COG3209	COG3209 Rhs family protein
YPK_0412	COG3501	Rhs element vgr protein
YPK_0414	COG0673	inositol 2-dehydrogenase activity
YPK_0415	COG2207	Transcriptional regulator
YPK_0416	COG1869	D-ribose catabolic process
YPK_0417	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPK_0421	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPK_0423	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPK_0425	COG3077	Addiction module antitoxin, RelB DinJ family
YPK_0426	COG2252	PERMEase
YPK_0427	COG3328	transposase activity
YPK_0428	COG0025	NhaP-type Na H and K H
YPK_0430	COG1560	Kdo2-lipid A biosynthetic process
YPK_0432	COG1129	ABC transporter
YPK_0433	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_0435	COG1069	ribulokinase activity
YPK_0437	COG0625	glutathione transferase activity
YPK_0442	COG1278	Cold shock
YPK_0443	COG1278	Cold shock
YPK_0444	COG1278	Cold shock
YPK_0445	COG3133	Outer membrane lipoprotein
YPK_0446	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPK_0448	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPK_0452	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
YPK_0453	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPK_0455	COG4145	pantothenate transmembrane transporter activity
YPK_0456	COG3924	membrane
YPK_0458	COG0439	Biotin carboxylase
YPK_0459	COG0511	ligase activity, forming carbon-carbon bonds
YPK_0463	COG0604	alcohol dehydrogenase
YPK_0464	COG2200	EAL domain
YPK_0464	COG2199	diguanylate cyclase activity
YPK_0465	COG1077	Cell shape determining protein MreB Mrl
YPK_0466	COG1792	Involved in formation and maintenance of cell shape
YPK_0467	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
YPK_0469	COG1530	ribonuclease E activity
YPK_0470	COG3164	Protein of unknown function
YPK_0471	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPK_0472	COG0312	modulator of DNA gyrase
YPK_0482	COG0583	DNA-binding transcription factor activity
YPK_0488	COG2732	(Barnase) inhibitor
YPK_0490	COG0312	modulator of DNA gyrase
YPK_0492	COG3783	Cytochrome b(562)
YPK_0493	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPK_0494	COG0366	Alpha amylase catalytic
YPK_0495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPK_0495	COG1263	PTS System
YPK_0496	COG1609	Transcriptional regulator
YPK_0501	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPK_0503	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPK_0505	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
YPK_0506	COG1137	ATPase activity
YPK_0507	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
YPK_0508	COG3117	lipopolysaccharide transmembrane transporter activity
YPK_0509	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
YPK_0510	COG0517	IMP dehydrogenase activity
YPK_0510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
YPK_0511	COG0530	calcium, potassium:sodium antiporter activity
YPK_0512	COG1127	ABC transporter
YPK_0513	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
YPK_0514	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPK_0515	COG2854	intermembrane phospholipid transfer
YPK_0516	COG3113	response to antibiotic
YPK_0517	COG5007	Belongs to the BolA IbaG family
YPK_0519	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPK_0520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPK_0521	COG3105	Protein conserved in bacteria
YPK_0523	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
YPK_0526	COG0625	glutathione transferase activity
YPK_0527	COG2969	positive regulation of protein catabolic process
YPK_0529	COG0493	'glutamate synthase
YPK_0530	COG0070	glutamate synthase
YPK_0530	COG0069	glutamate synthase activity
YPK_0530	COG0067	glutamate synthase
YPK_0531	COG1242	4 iron, 4 sulfur cluster binding
YPK_0533	COG0784	Response regulator, receiver
YPK_0533	COG5002	protein histidine kinase activity
YPK_0533	COG2198	Histidine kinase
YPK_0534	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
YPK_0536	COG2823	Periplasmic or secreted lipoprotein
YPK_0540	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
YPK_0541	COG1741	Belongs to the pirin family
YPK_0542	COG0583	DNA-binding transcription factor activity
YPK_0543	COG0435	Glutathione S-transferase
YPK_0544	COG2259	Doxx family
YPK_0546	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
YPK_0547	COG4575	ribosome binding
YPK_0550	COG0586	Pfam SNARE associated Golgi protein
YPK_0553	COG2271	Major facilitator Superfamily
YPK_0555	COG0246	Mannitol dehydrogenase
YPK_0556	COG2721	sulfolactate sulfo-lyase activity
YPK_0559	COG0673	inositol 2-dehydrogenase activity
YPK_0560	COG1451	nucleotide metabolic process
YPK_0563	COG1902	pentaerythritol trinitrate reductase activity
YPK_0563	COG0446	pyridine nucleotide-disulphide oxidoreductase
YPK_0564	COG3247	response to pH
YPK_0567	COG4245	von Willebrand factor, type A
YPK_0570	COG4245	von Willebrand factor, type A
YPK_0571	COG2831	hemolysin activation secretion protein
YPK_0572	COG3210	domain, Protein
YPK_0577	COG3210	domain, Protein
YPK_0579	COG3210	domain, Protein
YPK_0582	COG3210	domain, Protein
YPK_0586	COG3842	ATPase activity
YPK_0587	COG3459	Glycosyltransferase 36 associated
YPK_0588	COG1609	Transcriptional regulator
YPK_0589	COG1653	transport
YPK_0591	COG0395	ABC-type sugar transport system, permease component
YPK_0595	COG1289	transmembrane transporter activity
YPK_0603	COG0251	oxidation-reduction process
YPK_0610	COG3157	Type VI secretion system effector, Hcp
YPK_0617	COG3561	AntA/AntB antirepressor
YPK_0634	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPK_0635	COG0358	DNA primase activity
YPK_0639	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
YPK_0642	COG4991	sh3 domain protein
YPK_0643	COG3025	triphosphatase activity
YPK_0646	COG0531	amino acid
YPK_0650	COG3384	dioxygenase
YPK_0651	COG0754	glutathionylspermidine amidase activity
YPK_0654	COG1538	Outer membrane efflux protein
YPK_0655	COG0494	nUDIX hydrolase
YPK_0656	COG3151	Protein conserved in bacteria
YPK_0657	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
YPK_0658	COG3150	esterase
YPK_0659	COG0187	DNA topoisomerase II activity
YPK_0660	COG0583	DNA-binding transcription factor activity
YPK_0661	COG2249	NAD(P)H dehydrogenase (quinone) activity
YPK_0662	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
YPK_0663	COG0204	Acyl-transferase
YPK_0665	COG2132	Multicopper oxidase
YPK_0667	COG0656	L-ascorbic acid biosynthetic process
YPK_0668	COG1979	alcohol dehydrogenase
YPK_0669	COG2207	Transcriptional regulator
YPK_0670	COG0586	Pfam SNARE associated Golgi protein
YPK_0671	COG0626	cystathionine gamma-synthase activity
YPK_0672	COG0811	peptide transport
YPK_0673	COG0848	biopolymer transport protein
YPK_0685	COG4964	Belongs to the GSP D family
YPK_0692	COG3397	chitin binding
YPK_0693	COG3469	chitinase activity
YPK_0698	COG4592	Periplasmic binding protein
YPK_0703	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPK_0704	COG1684	flagellar biosynthetic protein fliR
YPK_0705	COG1987	bacterial-type flagellum assembly
YPK_0709	COG2204	response regulator
YPK_0718	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
YPK_0719	COG1815	bacterial-type flagellum-dependent cell motility
YPK_0720	COG1558	bacterial-type flagellum-dependent cell motility
YPK_0721	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPK_0722	COG1749	Flagellar hook protein flgE
YPK_0725	COG3710	Transcriptional regulator
YPK_0730	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
YPK_0736	COG3133	Outer membrane lipoprotein
YPK_0737	COG3300	MHYT domain
YPK_0737	COG5001	Diguanylate cyclase
YPK_0738	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPK_0740	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPK_0748	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
YPK_0749	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPK_0750	COG4771	TonB-dependent receptor
YPK_0751	COG3433	isochorismatase activity
YPK_0751	COG2226	methyltransferase
YPK_0751	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPK_0752	COG3433	isochorismatase activity
YPK_0752	COG2226	methyltransferase
YPK_0752	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
YPK_0758	COG1132	(ABC) transporter
YPK_0762	COG2610	gluconate transmembrane transporter activity
YPK_0764	COG3501	Rhs element vgr protein
YPK_0766	COG3209	COG3209 Rhs family protein
YPK_0768	COG3209	COG3209 Rhs family protein
YPK_0770	COG3209	COG3209 Rhs family protein
YPK_0772	COG3209	COG3209 Rhs family protein
YPK_0778	COG0471	metal ion transport
YPK_0779	COG1609	Transcriptional regulator
YPK_0781	COG2211	Major facilitator Superfamily
YPK_0791	COG2771	luxR family
YPK_0792	COG3916	Acyl-homoserine-lactone synthase
YPK_0811	COG1982	Orn Lys Arg decarboxylase major
YPK_0812	COG1879	ABC-type sugar transport system periplasmic component
YPK_0813	COG1129	ABC transporter
YPK_0814	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_0815	COG4774	siderophore transport
YPK_0820	COG1194	a g-specific adenine glycosylase
YPK_0822	COG3171	Protein conserved in bacteria
YPK_0823	COG2066	Belongs to the glutaminase family
YPK_0825	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
YPK_0825	COG3064	Membrane
YPK_0825	COG1073	alpha beta
YPK_0826	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPK_0827	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
YPK_0829	COG0762	integral membrane protein
YPK_0831	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
YPK_0832	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
YPK_0833	COG2805	Type II/IV secretion system protein
YPK_0835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPK_0838	COG0189	ligase activity
YPK_0839	COG1385	rRNA (uridine-N3-)-methyltransferase activity
YPK_0841	COG2356	endonuclease I
YPK_0845	COG1166	arginine decarboxylase activity
YPK_0846	COG1943	Transposase
YPK_0848	COG1943	Transposase
YPK_0849	COG0501	Belongs to the peptidase M48B family
YPK_0850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
YPK_0853	COG0191	fructose-bisphosphate aldolase activity
YPK_0858	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YPK_0859	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
YPK_0860	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
YPK_0863	COG0006	proline dipeptidase activity
YPK_0864	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPK_0865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPK_0871	COG5295	Hep Hag repeat protein
YPK_0873	COG1272	protein, Hemolysin III
YPK_0876	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
YPK_0878	COG0745	RESPONSE REGULATOR receiver
YPK_0879	COG2205	protein histidine kinase activity
YPK_0880	COG4452	Inner membrane protein CreD
YPK_0881	COG0716	FMN binding
YPK_0896	COG4695	Portal protein
YPK_0914	COG5301	cellulose 1,4-beta-cellobiosidase activity
YPK_0920	COG4974	Belongs to the 'phage' integrase family
YPK_0921	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPK_0922	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
YPK_0925	COG0582	viral genome integration into host DNA
YPK_0961	COG1695	Transcriptional regulator
YPK_0962	COG0791	NLP P60 protein
YPK_0964	COG1879	ABC-type sugar transport system periplasmic component
YPK_0965	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_0966	COG1129	ABC transporter
YPK_0968	COG2182	Extracellular solute-binding protein
YPK_0970	COG1175	transmembrane transport
YPK_0971	COG3833	ABC-type maltose transport systems, permease component
YPK_0972	COG3867	Arabinogalactan endo-beta-1,4-galactanase
YPK_0973	COG1874	Beta-galactosidase
YPK_0974	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPK_0974	COG1263	PTS System
YPK_0978	COG2271	Major facilitator Superfamily
YPK_0982	COG0191	fructose-bisphosphate aldolase activity
YPK_0984	COG3119	arylsulfatase activity
YPK_0985	COG0641	radical SAM
YPK_0987	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_0989	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPK_0990	COG3716	PTS system mannose fructose sorbose family IID component
YPK_0991	COG3715	PTS system
YPK_0992	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPK_0993	COG2222	sugar isomerase
YPK_0995	COG1349	DNA-binding transcription factor activity
YPK_0996	COG3119	arylsulfatase activity
YPK_1001	COG0288	reversible hydration of carbon dioxide
YPK_1018	COG0840	transmembrane signaling receptor activity
YPK_1022	COG2814	Major facilitator Superfamily
YPK_1023	COG0583	DNA-binding transcription factor activity
YPK_1024	COG0019	diaminopimelate decarboxylase activity
YPK_1025	COG1609	Transcriptional regulator
YPK_1031	COG0667	Aldo Keto reductase
YPK_1041	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
YPK_1043	COG1074	ATP-dependent DNA helicase activity
YPK_1044	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
YPK_1046	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPK_1047	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
YPK_1048	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
YPK_1049	COG2166	iron-sulfur cluster assembly
YPK_1050	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
YPK_1052	COG0583	DNA-binding transcription factor activity
YPK_1053	COG2363	Small membrane protein
YPK_1056	COG1611	Belongs to the LOG family
YPK_1059	COG3098	single-species biofilm formation
YPK_1060	COG0564	pseudouridine synthase activity
YPK_1065	COG0024	Methionine aminopeptidase
YPK_1071	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
YPK_1072	COG0575	Belongs to the CDS family
YPK_1073	COG0750	zinc metalloprotease
YPK_1075	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
YPK_1079	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
YPK_1081	COG0587	DNA-directed DNA polymerase activity
YPK_1083	COG0346	lactoylglutathione lyase activity
YPK_1086	COG4568	rho-dependent transcription termination
YPK_1088	COG4681	YaeQ
YPK_1090	COG3015	lipoprotein NlpE involved in copper resistance
YPK_1092	COG1720	tRNA m6t6A37 methyltransferase activity
YPK_1094	COG1464	Belongs to the NlpA lipoprotein family
YPK_1095	COG2011	ABC-type metal ion transport system permease component
YPK_1097	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
YPK_1101	COG0656	L-ascorbic acid biosynthetic process
YPK_1105	COG0741	lytic transglycosylase activity
YPK_1105	COG1388	LysM domain
YPK_1107	COG2226	methyltransferase
YPK_1109	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
YPK_1110	COG1953	Uracil, thiamine, allantoin
YPK_1113	COG2113	Glycine betaine
YPK_1114	COG4176	ABC-type proline glycine betaine transport system permease component
YPK_1115	COG4175	Glycine betaine
YPK_1116	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
YPK_1124	COG1278	Cold shock
YPK_1125	COG0747	negative chemotaxis
YPK_1127	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPK_1128	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
YPK_1129	COG1124	(ABC) transporter
YPK_1136	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
YPK_1138	COG4413	Urea transporter
YPK_1139	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
YPK_1141	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPK_1142	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPK_1144	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPK_1145	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
YPK_1146	COG1447	Phosphotransferase system cellobiose-specific component IIA
YPK_1147	COG1917	Cupin 2, conserved barrel domain protein
YPK_1147	COG2169	Transcriptional regulator
YPK_1151	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
YPK_1152	COG0033	Phosphoglucomutase
YPK_1155	COG0745	RESPONSE REGULATOR receiver
YPK_1156	COG2205	protein histidine kinase activity
YPK_1162	COG3272	Protein of unknown function (DUF1722)
YPK_1164	COG5212	phosphodiesterase
YPK_1165	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
YPK_1167	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
YPK_1168	COG1984	allophanate hydrolase subunit 2
YPK_1179	COG0513	Belongs to the DEAD box helicase family
YPK_1181	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
YPK_1183	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
YPK_1184	COG3026	antisigma factor binding
YPK_1185	COG3086	response to oxidative stress
YPK_1188	COG0681	Belongs to the peptidase S26 family
YPK_1192	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
YPK_1194	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPK_1248	COG1737	Transcriptional regulator
YPK_1250	COG0560	Phosphoserine phosphatase
YPK_1251	COG0590	tRNA wobble adenosine to inosine editing
YPK_1257	COG2205	protein histidine kinase activity
YPK_1258	COG3170	Tfp pilus assembly protein FimV
YPK_1259	COG2204	response regulator
YPK_1261	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
YPK_1261	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
YPK_1262	COG0347	Belongs to the P(II) protein family
YPK_1263	COG2188	Transcriptional regulator
YPK_1264	COG1017	nitric oxide dioxygenase activity
YPK_1264	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPK_1269	COG2814	Major facilitator Superfamily
YPK_1270	COG3711	transcriptional antiterminator
YPK_1271	COG3683	transport system, periplasmic component
YPK_1272	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
YPK_1273	COG0483	inositol monophosphate 1-phosphatase activity
YPK_1276	COG1104	cysteine desulfurase activity
YPK_1277	COG0822	iron-sulfur transferase activity
YPK_1281	COG0633	Ferredoxin
YPK_1282	COG2975	iron-sulfur cluster assembly
YPK_1286	COG3468	outer membrane autotransporter barrel domain protein
YPK_1295	COG2976	Protein conserved in bacteria
YPK_1296	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPK_1299	COG1645	bacterial-type flagellum-dependent swarming motility
YPK_1302	COG0516	GMP reductase activity
YPK_1302	COG0517	IMP dehydrogenase activity
YPK_1321	COG0351	phosphomethylpyrimidine kinase
YPK_1326	COG3422	double-strand break repair
YPK_1327	COG0745	RESPONSE REGULATOR receiver
YPK_1328	COG2205	protein histidine kinase activity
YPK_1333	COG3842	ATPase activity
YPK_1335	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
YPK_1337	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPK_1338	COG1177	transmembrane transport
YPK_1340	COG0443	Heat shock 70 kDa protein
YPK_1341	COG2239	Acts as a magnesium transporter
YPK_1343	COG0248	Ppx GppA phosphatase
YPK_1344	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
YPK_1346	COG0581	inorganic phosphate transmembrane transporter activity
YPK_1349	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPK_1350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
YPK_1353	COG2233	PERMEase
YPK_1355	COG1393	Belongs to the ArsC family
YPK_1356	COG4783	chaperone-mediated protein folding
YPK_1357	COG0628	permease
YPK_1360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
YPK_1361	COG2716	regulation of RNA biosynthetic process
YPK_1363	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
YPK_1366	COG2321	neutral zinc metallopeptidase
YPK_1371	COG1876	peptidase activity
YPK_1373	COG1393	Belongs to the ArsC family
YPK_1375	COG1840	ABC-type Fe3 transport system, periplasmic component
YPK_1376	COG1175	transmembrane transport
YPK_1377	COG3842	ATPase activity
YPK_1378	COG3119	arylsulfatase activity
YPK_1379	COG0641	radical SAM
YPK_1380	COG1988	membrane-bound metal-dependent
YPK_1382	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPK_1384	COG2197	response regulator
YPK_1385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPK_1385	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPK_1386	COG3062	negative regulation of establishment of protein localization
YPK_1388	COG3043	anaerobic respiration
YPK_1389	COG3005	denitrification pathway
YPK_1397	COG3111	PFAM Bacterial OB fold (BOF) protein
YPK_1399	COG2837	iron assimilation
YPK_1400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
YPK_1403	COG4886	Leucine-rich repeat (LRR) protein
YPK_1405	COG2731	YhcH YjgK YiaL family protein
YPK_1406	COG1737	Transcriptional regulator
YPK_1408	COG4150	thiosulfate binding
YPK_1409	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
YPK_1410	COG4208	sulfate ABC transporter
YPK_1412	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YPK_1414	COG0745	RESPONSE REGULATOR receiver
YPK_1415	COG5002	protein histidine kinase activity
YPK_1415	COG3850	Histidine kinase
YPK_1417	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPK_1418	COG0006	proline dipeptidase activity
YPK_1420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
YPK_1423	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPK_1424	COG0745	RESPONSE REGULATOR receiver
YPK_1425	COG2205	protein histidine kinase activity
YPK_1426	COG2190	(PTS) system
YPK_1428	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPK_1429	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
YPK_1430	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
YPK_1433	COG3530	Putative quorum-sensing-regulated virulence factor
YPK_1438	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPK_1441	COG0667	Aldo Keto reductase
YPK_1446	COG0436	Aminotransferase
YPK_1447	COG3038	cytochrome b561
YPK_1453	COG3381	protein complex oligomerization
YPK_1454	COG3302	dmso reductase anchor subunit
YPK_1455	COG0437	4 iron, 4 sulfur cluster binding
YPK_1456	COG0243	molybdopterin cofactor binding
YPK_1464	COG2951	lytic endotransglycosylase activity
YPK_1476	COG3121	Chaperone
YPK_1477	COG3188	usher protein
YPK_1486	COG3501	Rhs element vgr protein
YPK_1492	COG2824	Alkylphosphonate utilization operon protein PhnA
YPK_1494	COG1704	LemA family
YPK_1497	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPK_1498	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPK_1499	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
YPK_1501	COG1138	Cytochrome C-type biogenesis protein
YPK_1502	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
YPK_1503	COG4235	cytochrome complex assembly
YPK_1503	COG3088	subunit of a heme lyase
YPK_1504	COG3088	subunit of a heme lyase
YPK_1504	COG4235	cytochrome complex assembly
YPK_1507	COG3691	Protein conserved in bacteria
YPK_1511	COG2062	phosphohistidine phosphatase, SixA
YPK_1513	COG2890	protein-(glutamine-N5) methyltransferase activity
YPK_1516	COG0730	response to heat
YPK_1517	COG3101	peptidyl-lysine hydroxylation
YPK_1520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPK_1521	COG1794	racemase activity, acting on amino acids and derivatives
YPK_1524	COG0697	spore germination
YPK_1528	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
YPK_1530	COG0586	Pfam SNARE associated Golgi protein
YPK_1532	COG0285	dihydrofolate synthase activity
YPK_1533	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
YPK_1534	COG1286	toxin biosynthetic process
YPK_1535	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
YPK_1536	COG0163	prenyltransferase activity
YPK_1538	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPK_1539	COG4215	(ABC) transporter
YPK_1540	COG4160	amino acid transport
YPK_1541	COG4598	ABC transporter
YPK_1542	COG1090	epimerase
YPK_1544	COG0622	Phosphoesterase
YPK_1545	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
YPK_1546	COG3037	sugar-specific permease SgaT UlaA
YPK_1549	COG1609	Transcriptional regulator
YPK_1550	COG0857	belongs to the CobB CobQ family
YPK_1550	COG0280	phosphate acetyltransferase
YPK_1554	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPK_1555	COG0490	domain, Protein
YPK_1555	COG0471	metal ion transport
YPK_1558	COG0436	Aminotransferase
YPK_1559	COG0583	DNA-binding transcription factor activity
YPK_1561	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPK_1563	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
YPK_1565	COG1034	ATP synthesis coupled electron transport
YPK_1568	COG0839	Belongs to the complex I subunit 6 family
YPK_1570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
YPK_1571	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPK_1574	COG2731	YhcH YjgK YiaL family protein
YPK_1575	COG3265	gluconokinase activity
YPK_1576	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_1578	COG1609	Transcriptional regulator
YPK_1579	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPK_1582	COG0129	dihydroxy-acid dehydratase activity
YPK_1585	COG4575	ribosome binding
YPK_1588	COG1169	isochorismate synthase
YPK_1591	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
YPK_1594	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
YPK_1598	COG1126	abc transporter atp-binding protein
YPK_1599	COG0765	amino acid transport
YPK_1600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPK_1606	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPK_1610	COG1063	alcohol dehydrogenase
YPK_1611	COG1879	ABC-type sugar transport system periplasmic component
YPK_1612	COG1129	ABC transporter
YPK_1613	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_1614	COG1609	Transcriptional regulator
YPK_1615	COG0583	DNA-binding transcription factor activity
YPK_1616	COG0473	3-isopropylmalate dehydrogenase activity
YPK_1618	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPK_1619	COG4638	Rieske (2fe-2S)
YPK_1620	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPK_1621	COG2831	hemolysin activation secretion protein
YPK_1622	COG3210	domain, Protein
YPK_1624	COG2963	transposase activity
YPK_1625	COG3210	domain, Protein
YPK_1628	COG1476	TRANSCRIPTIONal
YPK_1629	COG3210	domain, Protein
YPK_1631	COG3842	ATPase activity
YPK_1633	COG1609	Transcriptional regulator
YPK_1636	COG0395	ABC-type sugar transport system, permease component
YPK_1637	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
YPK_1641	COG0668	transmembrane transport
YPK_1644	COG1518	maintenance of DNA repeat elements
YPK_1645	COG1203	CRISPR-associated helicase, Cas3
YPK_1650	COG0667	Aldo Keto reductase
YPK_1652	COG0477	Major facilitator Superfamily
YPK_1654	COG0583	DNA-binding transcription factor activity
YPK_1655	COG2771	luxR family
YPK_1656	COG3916	Acyl-homoserine-lactone synthase
YPK_1661	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
YPK_1662	COG2943	transferase activity, transferring hexosyl groups
YPK_1663	COG5645	(Lipo)protein
YPK_1664	COG3104	oligopeptide transport
YPK_1665	COG1560	Kdo2-lipid A biosynthetic process
YPK_1669	COG0628	permease
YPK_1676	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
YPK_1677	COG1530	ribonuclease E activity
YPK_1678	COG0564	pseudouridine synthase activity
YPK_1679	COG1943	Transposase
YPK_1681	COG1399	metal-binding, possibly nucleic acid-binding protein
YPK_1682	COG0333	Belongs to the bacterial ribosomal protein bL32 family
YPK_1686	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_1688	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPK_1689	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPK_1690	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
YPK_1692	COG0470	DNA polymerase III
YPK_1693	COG0084	hydrolase, TatD family'
YPK_1694	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPK_1694	COG1263	PTS System
YPK_1695	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
YPK_1696	COG0537	adenosine 5'-monophosphoramidase activity
YPK_1697	COG5633	Lipoprotein
YPK_1702	COG1252	NADH dehydrogenase
YPK_1705	COG3134	Outer membrane lipoprotein
YPK_1706	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
YPK_1707	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPK_1709	COG4591	ABC-type transport system involved in lipoprotein release permease component
YPK_1711	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
YPK_1713	COG2850	peptidyl-arginine hydroxylation
YPK_1715	COG0745	RESPONSE REGULATOR receiver
YPK_1718	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
YPK_1722	COG1187	pseudouridine synthase activity
YPK_1723	COG0538	isocitrate dehydrogenase activity
YPK_1726	COG0840	transmembrane signaling receptor activity
YPK_1727	COG0702	epimerase
YPK_1728	COG1733	regulation of RNA biosynthetic process
YPK_1733	COG1522	sequence-specific DNA binding
YPK_1737	COG0604	alcohol dehydrogenase
YPK_1737	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_1737	COG3321	synthase
YPK_1740	COG1278	Cold shock
YPK_1742	COG0840	transmembrane signaling receptor activity
YPK_1743	COG1285	pathogenesis
YPK_1748	COG1360	Flagellar Motor Protein
YPK_1749	COG2198	Histidine kinase
YPK_1749	COG0643	Histidine kinase
YPK_1750	COG0835	chemotaxis
YPK_1753	COG0840	transmembrane signaling receptor activity
YPK_1756	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
YPK_1758	COG0745	RESPONSE REGULATOR receiver
YPK_1759	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
YPK_1760	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPK_1761	COG5295	Hep Hag repeat protein
YPK_1761	COG5295	Hep Hag repeat protein
YPK_1761	COG5295	Hep Hag repeat protein
YPK_1764	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPK_1775	COG3121	Chaperone
YPK_1779	COG3008	intermembrane lipid transfer
YPK_1780	COG2995	paraquat-inducible protein a
YPK_1781	COG1956	GAF domain-containing protein
YPK_1783	COG0793	Belongs to the peptidase S41A family
YPK_1786	COG3539	Fimbrial protein
YPK_1787	COG3121	Chaperone
YPK_1790	COG3121	Chaperone
YPK_1791	COG2814	Major facilitator Superfamily
YPK_1792	COG0823	Involved in the tonB-independent uptake of proteins
YPK_1794	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPK_1796	COG1988	membrane-bound metal-dependent
YPK_1797	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
YPK_1798	COG1653	transport
YPK_1799	COG3842	ATPase activity
YPK_1800	COG0395	ABC-type sugar transport system, permease component
YPK_1801	COG1175	transmembrane transport
YPK_1803	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_1805	COG1917	Cupin 2, conserved barrel domain protein
YPK_1806	COG3328	transposase activity
YPK_1808	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPK_1812	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPK_1813	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPK_1814	COG1121	(ABC) transporter
YPK_1815	COG0803	Belongs to the bacterial solute-binding protein 9 family
YPK_1819	COG4249	Peptidase C14 caspase catalytic subunit p20
YPK_1826	COG0776	regulation of translation
YPK_1829	COG0386	Belongs to the glutathione peroxidase family
YPK_1830	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
YPK_1838	COG0791	NLP P60 protein
YPK_1843	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPK_1843	COG0574	Belongs to the PEP-utilizing enzyme family
YPK_1844	COG0628	permease
YPK_1845	COG0277	FAD linked oxidase domain protein
YPK_1845	COG0247	lactate metabolic process
YPK_1846	COG2050	protein possibly involved in aromatic compounds catabolism
YPK_1847	COG0316	Belongs to the HesB IscA family
YPK_1848	COG0719	Fe-S assembly protein
YPK_1849	COG0396	ATPase activity
YPK_1850	COG0719	Fe-S assembly protein
YPK_1853	COG1376	ErfK ybiS ycfS ynhG family protein
YPK_1853	COG1388	LysM domain
YPK_1854	COG4238	major outer membrane lipoprotein
YPK_1857	COG0307	riboflavin synthase, alpha
YPK_1858	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
YPK_1859	COG2814	Major facilitator Superfamily
YPK_1860	COG0583	DNA-binding transcription factor activity
YPK_1863	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
YPK_1864	COG0791	NLP P60 protein
YPK_1866	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
YPK_1869	COG0346	lactoylglutathione lyase activity
YPK_1871	COG1902	pentaerythritol trinitrate reductase activity
YPK_1872	COG1309	transcriptional regulator
YPK_1873	COG2194	sulfuric ester hydrolase activity
YPK_1874	COG3313	Fe-S protein
YPK_1875	COG4989	oxidoreductase activity
YPK_1877	COG3133	Outer membrane lipoprotein
YPK_1879	COG3895	Periplasmic Protein
YPK_1883	COG0625	glutathione transferase activity
YPK_1886	COG3104	oligopeptide transport
YPK_1887	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPK_1887	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
YPK_1888	COG4172	Belongs to the ABC transporter superfamily
YPK_1890	COG4171	peptide transport system, permease
YPK_1891	COG4168	peptide transport system, permease
YPK_1892	COG4166	transmembrane transport
YPK_1893	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
YPK_1894	COG1842	Phage shock protein A
YPK_1896	COG1983	PspC domain protein
YPK_1898	COG3106	COG3106 Predicted ATPase
YPK_1903	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
YPK_1904	COG4948	Mandelate Racemase Muconate Lactonizing
YPK_1905	COG2866	Carboxypeptidase
YPK_1906	COG4166	transmembrane transport
YPK_1910	COG0657	acetylesterase activity
YPK_1910	COG2755	lipolytic protein G-D-S-L family
YPK_1913	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
YPK_1913	COG0674	pyruvate-flavodoxin oxidoreductase activity
YPK_1913	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
YPK_1913	COG1013	pyruvate-flavodoxin oxidoreductase activity
YPK_1915	COG1285	pathogenesis
YPK_1916	COG3042	response to heat
YPK_1917	COG3187	Heat shock protein
YPK_1918	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
YPK_1919	COG2911	Protein conserved in bacteria
YPK_1921	COG3784	Protein of unknown function (DUF1318)
YPK_1922	COG0246	Mannitol dehydrogenase
YPK_1923	COG2390	Transcriptional regulator
YPK_1925	COG1643	Atp-dependent helicase
YPK_1928	COG3591	Belongs to the peptidase S1B family
YPK_1930	COG3038	cytochrome b561
YPK_1935	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
YPK_1936	COG2205	protein histidine kinase activity
YPK_1937	COG0745	RESPONSE REGULATOR receiver
YPK_1939	COG0531	amino acid
YPK_1941	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
YPK_1942	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
YPK_1943	COG0589	response to stress
YPK_1944	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
YPK_1945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPK_1948	COG1011	Hydrolase
YPK_1949	COG0440	acetolactate synthase activity
YPK_1950	COG0028	Belongs to the TPP enzyme family
YPK_1955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
YPK_1956	COG1116	anion transmembrane transporter activity
YPK_1957	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
YPK_1958	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
YPK_1961	COG1129	ABC transporter
YPK_1962	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_1963	COG1879	ABC-type sugar transport system periplasmic component
YPK_1965	COG1609	Transcriptional regulator
YPK_1967	COG1757	Na H antiporter
YPK_1968	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
YPK_1974	COG1012	belongs to the aldehyde dehydrogenase family
YPK_1975	COG3284	Transcriptional regulator
YPK_1976	COG4221	oxidoreductase activity
YPK_1980	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPK_1981	COG1940	carbohydrate kinase activity
YPK_1982	COG0583	DNA-binding transcription factor activity
YPK_1983	COG2814	Major facilitator Superfamily
YPK_1985	COG0114	fumarate hydratase activity
YPK_1986	COG1482	cell wall glycoprotein biosynthetic process
YPK_1987	COG5339	Protein conserved in bacteria
YPK_1989	COG2190	(PTS) system
YPK_1989	COG1263	PTS System
YPK_1989	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPK_1994	COG0385	Bile acid
YPK_1995	COG0673	inositol 2-dehydrogenase activity
YPK_1997	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_1999	COG1879	ABC-type sugar transport system periplasmic component
YPK_2002	COG2274	protein secretion by the type I secretion system
YPK_2004	COG2274	protein secretion by the type I secretion system
YPK_2009	COG2207	Transcriptional regulator
YPK_2009	COG3708	Transcriptional regulator
YPK_2011	COG4659	FMN binding
YPK_2013	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
YPK_2014	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPK_2015	COG2271	Major facilitator Superfamily
YPK_2017	COG1966	Carbon starvation protein
YPK_2018	COG2879	small protein
YPK_2019	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
YPK_2023	COG0023	Translation Initiation Factor
YPK_2026	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
YPK_2027	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
YPK_2028	COG0671	phosphoesterase, PA-phosphatase related
YPK_2029	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
YPK_2030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
YPK_2032	COG0583	DNA-binding transcription factor activity
YPK_2033	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPK_2036	COG0616	signal peptide processing
YPK_2037	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_2039	COG1187	pseudouridine synthase activity
YPK_2040	COG0009	L-threonylcarbamoyladenylate synthase
YPK_2043	COG0512	Glutamine amidotransferase of anthranilate synthase
YPK_2045	COG0135	phosphoribosylanthranilate isomerase activity
YPK_2045	COG0134	indole-3-glycerol-phosphate synthase activity
YPK_2049	COG3047	cAMP biosynthetic process
YPK_2054	COG1607	acyl-coa hydrolase
YPK_2055	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
YPK_2057	COG2350	Protein conserved in bacteria
YPK_2066	COG4608	Belongs to the ABC transporter superfamily
YPK_2067	COG0444	Belongs to the ABC transporter superfamily
YPK_2068	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPK_2069	COG0601	transmembrane transport
YPK_2071	COG2095	MarC family integral membrane protein
YPK_2072	COG1454	alcohol dehydrogenase
YPK_2072	COG1012	belongs to the aldehyde dehydrogenase family
YPK_2073	COG1435	thymidine kinase activity
YPK_2078	COG0745	RESPONSE REGULATOR receiver
YPK_2080	COG0788	formyltetrahydrofolate deformylase activity
YPK_2083	COG0583	DNA-binding transcription factor activity
YPK_2085	COG0708	Exodeoxyribonuclease III
YPK_2086	COG0494	nUDIX hydrolase
YPK_2088	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
YPK_2090	COG0778	Nitroreductase
YPK_2091	COG0616	signal peptide processing
YPK_2092	COG0252	asparaginase activity
YPK_2093	COG1335	isochorismatase
YPK_2094	COG3139	Protein of unknown function (DUF1315)
YPK_2098	COG3713	MltA-interacting MipA family protein
YPK_2100	COG2766	serine protein kinase
YPK_2104	COG0583	DNA-binding transcription factor activity
YPK_2106	COG2814	Major facilitator Superfamily
YPK_2108	COG2719	SpoVR family
YPK_2115	COG1104	cysteine desulfurase activity
YPK_2118	COG0179	Fumarylacetoacetate (FAA) hydrolase
YPK_2119	COG2951	lytic endotransglycosylase activity
YPK_2122	COG2894	cell division
YPK_2123	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
YPK_2124	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
YPK_2125	COG0318	PFAM AMP-dependent synthetase and ligase
YPK_2126	COG3065	identical protein binding
YPK_2128	COG1199	ATP-dependent helicase activity
YPK_2129	COG0251	oxidation-reduction process
YPK_2132	COG0800	Aldolase
YPK_2134	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
YPK_2135	COG1737	Transcriptional regulator
YPK_2136	COG0469	pyruvate kinase activity
YPK_2138	COG1560	Kdo2-lipid A biosynthetic process
YPK_2139	COG0739	heme binding
YPK_2140	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
YPK_2142	COG1108	ABC-type Mn2 Zn2 transport systems permease components
YPK_2147	COG0494	nUDIX hydrolase
YPK_2149	COG1801	Protein of unknown function DUF72
YPK_2150	COG3788	relative of glutathione S-transferase, MAPEG superfamily
YPK_2154	COG3102	Protein conserved in bacteria
YPK_2158	COG0728	peptidoglycan biosynthetic process
YPK_2161	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPK_2164	COG3381	protein complex oligomerization
YPK_2166	COG1940	carbohydrate kinase activity
YPK_2167	COG0584	glycerophosphoryl diester phosphodiesterase
YPK_2169	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPK_2170	COG3833	ABC-type maltose transport systems, permease component
YPK_2174	COG0659	secondary active sulfate transmembrane transporter activity
YPK_2176	COG2912	Transglutaminase-like superfamily
YPK_2177	COG3094	Invasion gene expression up-regulator, SirB
YPK_2178	COG2890	protein-(glutamine-N5) methyltransferase activity
YPK_2184	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
YPK_2187	COG0012	GTP binding
YPK_2193	COG5002	protein histidine kinase activity
YPK_2203	COG0500	methyltransferase
YPK_2216	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPK_2217	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
YPK_2220	COG0402	S-adenosylhomocysteine deaminase activity
YPK_2231	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPK_2232	COG3850	Histidine kinase
YPK_2233	COG0387	Pfam Sodium calcium exchanger
YPK_2234	COG1943	Transposase
YPK_2235	COG1702	phosphate starvation-inducible protein PhoH
YPK_2238	COG3658	cytochrome
YPK_2239	COG1215	transferase activity, transferring glycosyl groups
YPK_2240	COG1649	PFAM Uncharacterised BCR, COG1649
YPK_2240	COG0726	polysaccharide deacetylase
YPK_2241	COG0457	Tetratricopeptide repeat
YPK_2242	COG0006	proline dipeptidase activity
YPK_2246	COG1136	(ABC) transporter
YPK_2246	COG0577	efflux transmembrane transporter activity
YPK_2248	COG1136	(ABC) transporter
YPK_2248	COG0577	efflux transmembrane transporter activity
YPK_2252	COG0672	)-iron permease
YPK_2254	COG2066	Belongs to the glutaminase family
YPK_2255	COG1349	DNA-binding transcription factor activity
YPK_2257	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
YPK_2258	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPK_2267	COG2030	dehydratase
YPK_2268	COG0427	acetyl-CoA hydrolase
YPK_2274	COG3188	usher protein
YPK_2276	COG3121	Chaperone
YPK_2278	COG0395	ABC-type sugar transport system, permease component
YPK_2279	COG1175	transmembrane transport
YPK_2281	COG0673	inositol 2-dehydrogenase activity
YPK_2291	COG3328	transposase activity
YPK_2292	COG3328	transposase activity
YPK_2307	COG4974	Belongs to the 'phage' integrase family
YPK_2319	COG2176	DNA-directed DNA polymerase activity
YPK_2319	COG5002	protein histidine kinase activity
YPK_2325	COG4695	Portal protein
YPK_2356	COG2197	response regulator
YPK_2358	COG3136	membrane protein required for alginate biosynthesis
YPK_2361	COG1113	amino acid transport
YPK_2369	COG0506	proline dehydrogenase activity
YPK_2369	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPK_2369	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
YPK_2380	COG1191	sigma factor activity
YPK_2386	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
YPK_2387	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
YPK_2390	COG1677	Flagellar hook-basal body complex protein FliE
YPK_2392	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
YPK_2394	COG1157	protein secretion by the type III secretion system
YPK_2395	COG2882	bacterial-type flagellum organization
YPK_2398	COG1580	Controls the rotational direction of flagella during chemotaxis
YPK_2403	COG1987	bacterial-type flagellum assembly
YPK_2407	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPK_2408	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_2409	COG1129	ABC transporter
YPK_2411	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_2413	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_2413	COG3347	Dehydrogenase
YPK_2414	COG2390	Transcriptional regulator
YPK_2416	COG1256	bacterial-type flagellum assembly
YPK_2420	COG4786	Flagellar basal body rod
YPK_2422	COG1749	Flagellar hook protein flgE
YPK_2423	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
YPK_2424	COG1558	bacterial-type flagellum-dependent cell motility
YPK_2425	COG1815	bacterial-type flagellum-dependent cell motility
YPK_2427	COG2747	anti-sigma28 factor FlgM
YPK_2428	COG3418	PFAM FlgN family protein
YPK_2431	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPK_2432	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
YPK_2437	COG2372	response to copper ion
YPK_2438	COG1528	Iron-storage protein
YPK_2442	COG1770	oligopeptidase
YPK_2445	COG3141	response to X-ray
YPK_2446	COG0513	Belongs to the DEAD box helicase family
YPK_2451	COG1760	l-serine dehydratase
YPK_2452	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
YPK_2453	COG2368	4-hydroxyphenylacetate
YPK_2456	COG3971	2-oxopent-4-enoate hydratase activity
YPK_2458	COG3384	dioxygenase
YPK_2459	COG1012	belongs to the aldehyde dehydrogenase family
YPK_2462	COG1846	Transcriptional regulator
YPK_2463	COG1253	flavin adenine dinucleotide binding
YPK_2464	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPK_2464	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPK_2465	COG3715	PTS system
YPK_2466	COG3716	PTS system mannose fructose sorbose family IID component
YPK_2470	COG5001	Diguanylate cyclase
YPK_2470	COG5002	protein histidine kinase activity
YPK_2470	COG3447	MASE1 domain protein
YPK_2472	COG2226	methyltransferase
YPK_2474	COG1278	Cold shock
YPK_2477	COG1113	amino acid transport
YPK_2484	COG2207	Transcriptional regulator
YPK_2487	COG1132	(ABC) transporter
YPK_2492	COG2223	nitrite transmembrane transporter activity
YPK_2496	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
YPK_2500	COG3122	Protein conserved in bacteria
YPK_2504	COG0534	Mate efflux family protein
YPK_2508	COG4948	Mandelate Racemase Muconate Lactonizing
YPK_2510	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_2511	COG3011	Protein conserved in bacteria
YPK_2512	COG2271	Major facilitator Superfamily
YPK_2513	COG1470	cell adhesion involved in biofilm formation
YPK_2513	COG1388	LysM domain
YPK_2516	COG2925	Exonuclease
YPK_2517	COG0531	amino acid
YPK_2519	COG0371	Dehydrogenase
YPK_2520	COG1129	ABC transporter
YPK_2521	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_2524	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPK_2526	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
YPK_2529	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
YPK_2532	COG0140	phosphoribosyl-ATP diphosphatase activity
YPK_2532	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
YPK_2533	COG1943	Transposase
YPK_2536	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPK_2537	COG1210	Utp--glucose-1-phosphate uridylyltransferase
YPK_2538	COG4264	IucA IucC family
YPK_2540	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPK_2541	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPK_2542	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPK_2543	COG1120	ATPase activity
YPK_2546	COG3486	L-lysine 6-monooxygenase (NADPH) activity
YPK_2547	COG0076	glutamate decarboxylase activity
YPK_2548	COG4114	ferric iron reductase
YPK_2549	COG1253	flavin adenine dinucleotide binding
YPK_2550	COG2982	Protein involved in outer membrane biogenesis
YPK_2553	COG0489	protein tyrosine kinase activity
YPK_2558	COG2814	Major facilitator Superfamily
YPK_2560	COG1346	cytolysis
YPK_2563	COG2949	membrane
YPK_2564	COG4211	Belongs to the binding-protein-dependent transport system permease family
YPK_2567	COG2311	Membrane
YPK_2569	COG0477	Major facilitator Superfamily
YPK_2570	COG0583	DNA-binding transcription factor activity
YPK_2576	COG1136	(ABC) transporter
YPK_2578	COG0303	'Molybdopterin
YPK_2581	COG0488	(ABC) transporter
YPK_2602	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
YPK_2603	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
YPK_2605	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_2606	COG1024	Enoyl-CoA hydratase
YPK_2608	COG3425	synthase
YPK_2609	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_2610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPK_2611	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
YPK_2613	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_2618	COG2920	part of a sulfur-relay system
YPK_2622	COG1832	CoA-binding protein
YPK_2623	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
YPK_2625	COG0210	DNA helicase
YPK_2626	COG3304	Inner membrane component domain
YPK_2627	COG1289	transmembrane transporter activity
YPK_2628	COG3070	regulator of competence-specific genes
YPK_2630	COG2885	chlorophyll binding
YPK_2630	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
YPK_2631	COG1943	Transposase
YPK_2633	COG1067	ATP-dependent peptidase activity
YPK_2636	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
YPK_2637	COG3009	Protein conserved in bacteria
YPK_2638	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
YPK_2638	COG3008	intermembrane lipid transfer
YPK_2639	COG2995	paraquat-inducible protein a
YPK_2640	COG0488	(ABC) transporter
YPK_2642	COG3217	Mosc domain protein beta barrel domain protein
YPK_2642	COG0633	Ferredoxin
YPK_2645	COG0308	aminopeptidase N
YPK_2650	COG1448	Aminotransferase
YPK_2652	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
YPK_2653	COG3108	Peptidase M15
YPK_2654	COG2989	Protein conserved in bacteria
YPK_2656	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
YPK_2657	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
YPK_2658	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
YPK_2659	COG3173	Aminoglycoside phosphotransferase
YPK_2661	COG2835	tetraacyldisaccharide 4'-kinase activity
YPK_2662	COG1278	Cold shock
YPK_2663	COG5383	Protein conserved in bacteria
YPK_2666	COG0658	competence protein
YPK_2666	COG2333	competence protein COMEC
YPK_2668	COG0539	negative regulation of cytoplasmic translation
YPK_2674	COG0252	asparaginase activity
YPK_2675	COG1944	ATP diphosphatase activity
YPK_2676	COG2116	formate transmembrane transporter activity
YPK_2677	COG1882	Formate acetyltransferase
YPK_2679	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
YPK_2683	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
YPK_2685	COG1674	ftsk spoiiie
YPK_2685	COG3107	peptidoglycan biosynthetic process
YPK_2687	COG0492	ferredoxin-NADP+ reductase activity
YPK_2689	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
YPK_2691	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
YPK_2692	COG0542	response to heat
YPK_2694	COG1278	Cold shock
YPK_2696	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPK_2697	COG2990	Protein conserved in bacteria
YPK_2699	COG3593	DNA synthesis involved in DNA repair
YPK_2700	COG2431	L-lysine efflux transmembrane transporter activity
YPK_2702	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPK_2703	COG0028	Belongs to the TPP enzyme family
YPK_2705	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
YPK_2706	COG0702	epimerase
YPK_2707	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPK_2709	COG1605	Chorismate mutase
YPK_2710	COG1126	abc transporter atp-binding protein
YPK_2711	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPK_2712	COG4215	(ABC) transporter
YPK_2713	COG4160	amino acid transport
YPK_2718	COG1120	ATPase activity
YPK_2719	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPK_2724	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPK_2727	COG1177	transmembrane transport
YPK_2728	COG1176	ABC-type spermidine putrescine transport system, permease component I
YPK_2729	COG3842	ATPase activity
YPK_2730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
YPK_2733	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPK_2734	COG2985	domain, Protein
YPK_2734	COG0569	domain protein
YPK_2736	COG0671	phosphoesterase, PA-phosphatase related
YPK_2737	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPK_2738	COG1349	DNA-binding transcription factor activity
YPK_2739	COG0814	amino acid
YPK_2740	COG1686	Belongs to the peptidase S11 family
YPK_2741	COG2011	ABC-type metal ion transport system permease component
YPK_2747	COG0625	glutathione transferase activity
YPK_2748	COG4771	TonB-dependent receptor
YPK_2750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPK_2752	COG0833	amino acid
YPK_2754	COG0583	DNA-binding transcription factor activity
YPK_2755	COG2855	membrane
YPK_2757	COG3188	usher protein
YPK_2758	COG3121	Chaperone
YPK_2761	COG3710	Transcriptional regulator
YPK_2762	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
YPK_2762	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPK_2762	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPK_2763	COG1105	Belongs to the carbohydrate kinase PfkB family
YPK_2765	COG0494	nUDIX hydrolase
YPK_2766	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_2767	COG1129	ABC transporter
YPK_2769	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
YPK_2774	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_2778	COG1312	Catalyzes the dehydration of D-mannonate
YPK_2779	COG0246	Mannitol dehydrogenase
YPK_2780	COG2186	Transcriptional regulator
YPK_2782	COG0523	cobalamin synthesis protein
YPK_2783	COG0671	phosphoesterase, PA-phosphatase related
YPK_2784	COG0791	NLP P60 protein
YPK_2785	COG2200	EAL domain
YPK_2786	COG4166	transmembrane transport
YPK_2787	COG4174	ABC transporter (Permease)
YPK_2788	COG4239	(ABC) transporter, permease
YPK_2789	COG4172	Belongs to the ABC transporter superfamily
YPK_2792	COG2814	Major facilitator Superfamily
YPK_2793	COG1187	pseudouridine synthase activity
YPK_2794	COG1061	Type III restriction enzyme res subunit
YPK_2797	COG3082	Protein of unknown function (DUF1414)
YPK_2798	COG3083	sulfuric ester hydrolase activity
YPK_2800	COG3157	Type VI secretion system effector, Hcp
YPK_2805	COG2723	6-phospho-beta-galactosidase activity
YPK_2807	COG1737	Transcriptional regulator
YPK_2811	COG3299	homolog of phage Mu protein gp47
YPK_2819	COG4386	tail sheath protein
YPK_2823	COG3622	Belongs to the hyi family
YPK_2824	COG1349	DNA-binding transcription factor activity
YPK_2825	COG0235	Class ii aldolase
YPK_2826	COG3395	kinase activity
YPK_2836	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
YPK_2839	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
YPK_2841	COG2223	nitrite transmembrane transporter activity
YPK_2842	COG2198	Histidine kinase
YPK_2842	COG0642	Histidine kinase
YPK_2844	COG0784	Response regulator, receiver
YPK_2844	COG2205	protein histidine kinase activity
YPK_2850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPK_2853	COG0814	amino acid
YPK_2858	COG0697	spore germination
YPK_2860	COG1982	Orn Lys Arg decarboxylase major
YPK_2861	COG0531	amino acid
YPK_2862	COG1174	glycine betaine transport
YPK_2863	COG1125	glycine betaine transport
YPK_2864	COG1174	glycine betaine transport
YPK_2865	COG1732	Glycine betaine
YPK_2866	COG2897	thiosulfate sulfurtransferase activity
YPK_2869	COG0410	ABC transporter
YPK_2870	COG1122	ATPase activity
YPK_2874	COG4807	Protein conserved in bacteria
YPK_2877	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
YPK_2879	COG2261	transglycosylase associated protein
YPK_2881	COG1403	HNH endonuclease
YPK_2884	COG0277	FAD linked oxidase domain protein
YPK_2885	COG1686	Belongs to the peptidase S11 family
YPK_2887	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPK_2889	COG1943	Transposase
YPK_2891	COG0513	Belongs to the DEAD box helicase family
YPK_2898	COG0513	Belongs to the DEAD box helicase family
YPK_2899	COG1309	transcriptional regulator
YPK_2901	COG1131	(ABC) transporter
YPK_2902	COG0842	Transport permease protein
YPK_2903	COG0842	Transport permease protein
YPK_2906	COG1902	pentaerythritol trinitrate reductase activity
YPK_2910	COG2211	Major facilitator Superfamily
YPK_2911	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
YPK_2913	COG0583	DNA-binding transcription factor activity
YPK_2914	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
YPK_2918	COG0670	Belongs to the BI1 family
YPK_2919	COG0314	molybdopterin synthase activity
YPK_2920	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
YPK_2922	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
YPK_2924	COG0391	Required for morphogenesis under gluconeogenic growth conditions
YPK_2925	COG4628	conserved protein (DUF2132)
YPK_2928	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
YPK_2929	COG2226	methyltransferase
YPK_2934	COG0561	phosphatase activity
YPK_2936	COG4149	molybdate abc transporter
YPK_2937	COG0725	ABC transporter, periplasmic molybdate-binding protein
YPK_2939	COG3585	molybdate ion transport
YPK_2939	COG2005	Transcriptional regulator
YPK_2940	COG1119	ATPase activity
YPK_2943	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
YPK_2944	COG1085	galactose-1-phosphate uridylyltransferase
YPK_2946	COG2017	converts alpha-aldose to the beta-anomer
YPK_2949	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPK_2951	COG1230	cation diffusion facilitator family transporter
YPK_2954	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
YPK_2955	COG2885	chlorophyll binding
YPK_2957	COG3064	Membrane
YPK_2957	COG3064	Membrane
YPK_2958	COG0848	biopolymer transport protein
YPK_2959	COG0811	peptide transport
YPK_2960	COG0824	Thioesterase
YPK_2961	COG3790	cyd operon protein YbgE
YPK_2962	COG4890	Cyd operon protein YbgT
YPK_2963	COG1294	oxidase, subunit
YPK_2964	COG1271	oxidase subunit
YPK_2965	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
YPK_2967	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPK_2968	COG0567	Dehydrogenase, E1 component
YPK_2970	COG1053	succinate dehydrogenase
YPK_2971	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
YPK_2972	COG2009	succinate dehydrogenase
YPK_2975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
YPK_2976	COG0497	DNA recombination
YPK_2977	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPK_2979	COG2867	negative regulation of translational initiation
YPK_2981	COG0582	viral genome integration into host DNA
YPK_2982	COG2963	transposase activity
YPK_2983	COG0582	viral genome integration into host DNA
YPK_2986	COG0596	Alpha beta hydrolase
YPK_2991	COG0735	belongs to the Fur family
YPK_2995	COG1943	Transposase
YPK_2996	COG2190	(PTS) system
YPK_2996	COG1263	PTS System
YPK_2996	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
YPK_2998	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
YPK_2999	COG1940	carbohydrate kinase activity
YPK_2999	COG1846	Transcriptional regulator
YPK_3000	COG0647	UMP catabolic process
YPK_3001	COG0367	asparagine synthase
YPK_3004	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
YPK_3006	COG1702	phosphate starvation-inducible protein PhoH
YPK_3008	COG4535	Mg2 and Co2 transporter CorC
YPK_3009	COG0815	Transfers the fatty acyl group on membrane lipoproteins
YPK_3011	COG0765	amino acid transport
YPK_3012	COG0765	amino acid transport
YPK_3013	COG1126	abc transporter atp-binding protein
YPK_3014	COG2888	peptidyl-tyrosine sulfation
YPK_3017	COG1466	dna polymerase III delta subunit
YPK_3019	COG0799	negative regulation of ribosome biogenesis
YPK_3021	COG0768	penicillin binding
YPK_3022	COG0772	Belongs to the SEDS family
YPK_3023	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPK_3024	COG1686	Belongs to the peptidase S11 family
YPK_3028	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPK_3030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
YPK_3031	COG1278	Cold shock
YPK_3032	COG1278	Cold shock
YPK_3033	COG2197	response regulator
YPK_3037	COG5265	(ABC) transporter
YPK_3039	COG3718	enzyme involved in inositol metabolism
YPK_3041	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPK_3042	COG0673	inositol 2-dehydrogenase activity
YPK_3043	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_3044	COG1129	ABC transporter
YPK_3045	COG1879	ABC-type sugar transport system periplasmic component
YPK_3046	COG0673	inositol 2-dehydrogenase activity
YPK_3048	COG3962	Belongs to the TPP enzyme family
YPK_3053	COG2373	Large extracellular alpha-helical protein
YPK_3054	COG4953	penicillin-binding protein 1C
YPK_3055	COG3423	Transcriptional regulator
YPK_3067	COG2850	peptidyl-arginine hydroxylation
YPK_3068	COG3328	transposase activity
YPK_3069	COG1187	pseudouridine synthase activity
YPK_3075	COG0656	L-ascorbic acid biosynthetic process
YPK_3076	COG0667	Aldo Keto reductase
YPK_3080	COG0671	phosphoesterase, PA-phosphatase related
YPK_3080	COG2453	phosphatase
YPK_3081	COG2267	carboxylic ester hydrolase activity
YPK_3083	COG4589	Belongs to the CDS family
YPK_3084	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
YPK_3122	COG4386	tail sheath protein
YPK_3128	COG0582	viral genome integration into host DNA
YPK_3133	COG2003	Belongs to the UPF0758 family
YPK_3137	COG3596	GTP binding
YPK_3149	COG0582	viral genome integration into host DNA
YPK_3151	COG2501	S4 domain
YPK_3153	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
YPK_3155	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
YPK_3156	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
YPK_3157	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
YPK_3158	COG4181	ATPase activity
YPK_3159	COG2755	lipolytic protein G-D-S-L family
YPK_3160	COG0300	oxidoreductase activity
YPK_3161	COG3118	belongs to the thioredoxin family
YPK_3162	COG0330	HflC and HflK could
YPK_3163	COG1585	Membrane protein implicated in regulation of membrane protease activity
YPK_3164	COG0789	Transcriptional regulator
YPK_3165	COG2217	Heavy metal translocating P-type atpase
YPK_3166	COG3735	TraB family
YPK_3167	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
YPK_3172	COG2223	nitrite transmembrane transporter activity
YPK_3173	COG1943	Transposase
YPK_3174	COG2223	nitrite transmembrane transporter activity
YPK_3175	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
YPK_3175	COG4651	solute:proton antiporter activity
YPK_3176	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPK_3177	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPK_3179	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPK_3182	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPK_3183	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
YPK_3186	COG2244	polysaccharide biosynthetic process
YPK_3188	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
YPK_3192	COG0543	2 iron, 2 sulfur cluster binding
YPK_3192	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
YPK_3198	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
YPK_3204	COG1196	nuclear chromosome segregation
YPK_3204	COG3264	Mechanosensitive ion channel
YPK_3205	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
YPK_3206	COG1309	transcriptional regulator
YPK_3207	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPK_3208	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPK_3209	COG1943	Transposase
YPK_3211	COG0257	Belongs to the bacterial ribosomal protein bL36 family
YPK_3215	COG3695	enzyme binding
YPK_3216	COG3126	Type III secretion system lipoprotein chaperone (YscW)
YPK_3217	COG1946	Acyl-CoA thioesterase
YPK_3219	COG0004	ammonium transporteR
YPK_3220	COG0347	Belongs to the P(II) protein family
YPK_3221	COG1132	(ABC) transporter
YPK_3222	COG1132	(ABC) transporter
YPK_3223	COG1522	sequence-specific DNA binding
YPK_3226	COG4533	DNA binding
YPK_3228	COG0824	Thioesterase
YPK_3229	COG1555	photosystem II stabilization
YPK_3230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPK_3231	COG0776	regulation of translation
YPK_3232	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
YPK_3237	COG0271	Belongs to the BolA IbaG family
YPK_3238	COG3056	Lipoprotein
YPK_3239	COG2223	nitrite transmembrane transporter activity
YPK_3241	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
YPK_3242	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
YPK_3243	COG1845	cytochrome c oxidase, subunit III
YPK_3244	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
YPK_3246	COG2814	Major facilitator Superfamily
YPK_3248	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
YPK_3249	COG0693	protein deglycase activity
YPK_3252	COG0142	geranyltranstransferase activity
YPK_3254	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
YPK_3255	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
YPK_3258	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPK_3258	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
YPK_3261	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPK_3262	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
YPK_3263	COG1862	Preprotein translocase
YPK_3267	COG0450	alkyl hydroperoxide reductase
YPK_3270	COG0300	oxidoreductase activity
YPK_3271	COG0366	Alpha amylase catalytic
YPK_3273	COG1114	Component of the transport system for branched-chain amino acids
YPK_3275	COG5002	protein histidine kinase activity
YPK_3276	COG0745	RESPONSE REGULATOR receiver
YPK_3277	COG0420	3'-5' exonuclease activity
YPK_3278	COG0419	ATPase involved in DNA repair
YPK_3279	COG1940	carbohydrate kinase activity
YPK_3284	COG2226	methyltransferase
YPK_3295	COG2195	Cleaves the N-terminal amino acid of tripeptides
YPK_3299	COG1477	protein flavinylation
YPK_3303	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPK_3304	COG1805	sodium ion transport
YPK_3305	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
YPK_3306	COG3034	peptidoglycan biosynthetic process
YPK_3307	COG0121	glutamine amidotransferase
YPK_3309	COG1960	acyl-CoA dehydrogenase activity
YPK_3311	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
YPK_3316	COG1943	Transposase
YPK_3322	COG0436	Aminotransferase
YPK_3325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
YPK_3334	COG2814	Major facilitator Superfamily
YPK_3335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
YPK_3337	COG1846	Transcriptional regulator
YPK_3338	COG1566	PFAM secretion protein HlyD family protein
YPK_3339	COG2814	Major facilitator Superfamily
YPK_3340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPK_3341	COG3118	belongs to the thioredoxin family
YPK_3343	COG0045	succinate-CoA ligase (ADP-forming) activity
YPK_3343	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
YPK_3343	COG1042	CoA-binding domain protein
YPK_3344	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
YPK_3345	COG5544	Lipoprotein
YPK_3349	COG0542	response to heat
YPK_3351	COG0564	pseudouridine synthase activity
YPK_3352	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
YPK_3353	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
YPK_3355	COG0077	Prephenate dehydratase
YPK_3355	COG1605	Chorismate mutase
YPK_3356	COG0287	Prephenate dehydrogenase
YPK_3356	COG1605	Chorismate mutase
YPK_3357	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
YPK_3358	COG3279	Response regulator of the LytR AlgR family
YPK_3359	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPK_3360	COG3137	Salt-induced outer membrane protein
YPK_3365	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
YPK_3366	COG4137	Cytochrome C assembly protein
YPK_3367	COG4536	flavin adenine dinucleotide binding
YPK_3370	COG1238	metal cluster binding
YPK_3371	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPK_3372	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
YPK_3381	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPK_3382	COG3958	Transketolase
YPK_3383	COG3959	Transketolase, thiamine diphosphate binding domain
YPK_3384	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_3385	COG1129	ABC transporter
YPK_3389	COG3783	Cytochrome b(562)
YPK_3390	COG3038	cytochrome b561
YPK_3391	COG3381	protein complex oligomerization
YPK_3392	COG3302	dmso reductase anchor subunit
YPK_3393	COG0437	4 iron, 4 sulfur cluster binding
YPK_3394	COG0243	molybdopterin cofactor binding
YPK_3395	COG0235	Class ii aldolase
YPK_3397	COG1349	DNA-binding transcription factor activity
YPK_3399	COG1129	ABC transporter
YPK_3400	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_3401	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_3402	COG3623	hexulose-6-phosphate isomerase
YPK_3403	COG1070	Carbohydrate kinase
YPK_3404	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
YPK_3404	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
YPK_3406	COG0024	Methionine aminopeptidase
YPK_3409	COG4771	TonB-dependent receptor
YPK_3411	COG1858	cytochrome C peroxidase
YPK_3412	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPK_3416	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
YPK_3419	COG2376	Dihydroxyacetone kinase
YPK_3420	COG1028	Short-chain dehydrogenase reductase Sdr
YPK_3421	COG1063	alcohol dehydrogenase
YPK_3422	COG0698	ribose 5-phosphate isomerase
YPK_3425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
YPK_3426	COG4942	peptidase
YPK_3426	COG1388	LysM domain
YPK_3434	COG0529	Catalyzes the synthesis of activated sulfate
YPK_3443	COG0720	synthase
YPK_3444	COG0602	queuosine metabolic process
YPK_3448	COG3956	TIGRFAM MazG family protein
YPK_3449	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPK_3450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
YPK_3451	COG3850	Histidine kinase
YPK_3451	COG2205	protein histidine kinase activity
YPK_3451	COG3437	response regulator, receiver
YPK_3451	COG4999	Histidine kinase
YPK_3452	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
YPK_3456	COG2860	membrane
YPK_3460	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPK_3461	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
YPK_3462	COG1120	ATPase activity
YPK_3463	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
YPK_3464	COG1643	Atp-dependent helicase
YPK_3466	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
YPK_3468	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
YPK_3470	COG0617	tRNA 3'-terminal CCA addition
YPK_3471	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
YPK_3475	COG0726	polysaccharide deacetylase
YPK_3476	COG0842	Transport permease protein
YPK_3477	COG1131	(ABC) transporter
YPK_3478	COG0288	reversible hydration of carbon dioxide
YPK_3479	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
YPK_3480	COG2132	Multicopper oxidase
YPK_3485	COG0697	spore germination
YPK_3487	COG1049	propionate catabolic process, 2-methylcitrate cycle
YPK_3488	COG1943	Transposase
YPK_3489	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPK_3490	COG0508	dehydrogenase complex catalyzes the overall conversion of
YPK_3491	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
YPK_3492	COG2186	Transcriptional regulator
YPK_3494	COG1113	amino acid transport
YPK_3495	COG3725	Membrane protein required for beta-lactamase induction
YPK_3496	COG3023	N-Acetylmuramoyl-L-alanine amidase
YPK_3498	COG4969	Belongs to the N-Me-Phe pilin family
YPK_3499	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
YPK_3500	COG1459	type II secretion system
YPK_3503	COG0237	dephospho-CoA kinase activity
YPK_3506	COG1943	Transposase
YPK_3508	COG0494	nUDIX hydrolase
YPK_3513	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
YPK_3514	COG0849	cell division
YPK_3515	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
YPK_3519	COG0772	Belongs to the SEDS family
YPK_3522	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
YPK_3523	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
YPK_3524	COG0768	penicillin binding
YPK_3525	COG3116	cell division
YPK_3529	COG1609	Transcriptional regulator
YPK_3531	COG0028	Belongs to the TPP enzyme family
YPK_3532	COG1022	Amp-dependent synthetase and ligase
YPK_3536	COG0473	3-isopropylmalate dehydrogenase activity
YPK_3539	COG2814	Major facilitator Superfamily
YPK_3542	COG4143	(ABC) transporter
YPK_3543	COG1178	ABC-type Fe3 transport system permease component
YPK_3545	COG0586	Pfam SNARE associated Golgi protein
YPK_3546	COG0417	DNA replication proofreading
YPK_3551	COG3047	cAMP biosynthetic process
YPK_3551	COG2885	chlorophyll binding
YPK_3558	COG3501	Rhs element vgr protein
YPK_3568	COG0564	pseudouridine synthase activity
YPK_3569	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
YPK_3571	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPK_3578	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
YPK_3580	COG2966	Psort location CytoplasmicMembrane, score
YPK_3582	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
YPK_3583	COG0505	Belongs to the CarA family
YPK_3586	COG1047	Peptidyl-prolyl cis-trans
YPK_3589	COG0196	riboflavin kinase activity
YPK_3591	COG0583	DNA-binding transcription factor activity
YPK_3595	COG1584	GPR1 FUN34 yaaH family protein
YPK_3598	COG0521	Mo-molybdopterin cofactor biosynthetic process
YPK_3606	COG0745	RESPONSE REGULATOR receiver
YPK_3607	COG3045	CreA protein
YPK_3609	COG3708	Transcriptional regulator
YPK_3609	COG2207	Transcriptional regulator
YPK_3612	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
YPK_3613	COG0741	lytic transglycosylase activity
YPK_3616	COG2199	diguanylate cyclase activity
YPK_3617	COG2885	chlorophyll binding
YPK_3618	COG0488	(ABC) transporter
YPK_3622	COG0560	Phosphoserine phosphatase
YPK_3623	COG3726	membrane protein affecting hemolysin expression
YPK_3627	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
YPK_3628	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
YPK_3629	COG0084	hydrolase, TatD family'
YPK_3630	COG4667	esterase of the alpha-beta hydrolase superfamily
YPK_3632	COG2823	Periplasmic or secreted lipoprotein
YPK_3634	COG0456	acetyltransferase
YPK_3635	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
YPK_3638	COG3706	GGDEF domain
YPK_3642	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPK_3643	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
YPK_3647	COG0859	PFAM glycosyl transferase family 9
YPK_3649	COG2390	Transcriptional regulator
YPK_3657	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPK_3657	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
YPK_3657	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
YPK_3658	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPK_3659	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPK_3660	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
YPK_3661	COG2207	Transcriptional regulator
YPK_3663	COG4269	membrane
YPK_3666	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
YPK_3668	COG0582	viral genome integration into host DNA
YPK_3674	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
YPK_3676	COG0582	viral genome integration into host DNA
YPK_3677	COG0795	lipopolysaccharide-transporting ATPase activity
YPK_3678	COG0795	lipopolysaccharide-transporting ATPase activity
YPK_3680	COG2927	DNA polymerase III (CHI subunit)
YPK_3683	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
YPK_3685	COG2731	YhcH YjgK YiaL family protein
YPK_3687	COG0601	transmembrane transport
YPK_3688	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
YPK_3689	COG0444	Belongs to the ABC transporter superfamily
YPK_3690	COG4608	Belongs to the ABC transporter superfamily
YPK_3693	COG2188	Transcriptional regulator
YPK_3694	COG3624	Phosphonate C-P lyase system protein PhnG
YPK_3695	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
YPK_3696	COG3626	phosphonate metabolism
YPK_3697	COG3627	carbon phosphorus lyase activity
YPK_3698	COG4107	phosphonate C-P lyase system protein PhnK
YPK_3699	COG4778	phosphonate C-P lyase system protein PhnL
YPK_3700	COG3454	Phosphonate metabolism
YPK_3701	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
YPK_3702	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
YPK_3703	COG0702	epimerase
YPK_3706	COG3842	ATPase activity
YPK_3707	COG0395	ABC-type sugar transport system, permease component
YPK_3709	COG1653	transport
YPK_3713	COG3153	acetyltransferase
YPK_3718	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
YPK_3720	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
YPK_3724	COG0513	Belongs to the DEAD box helicase family
YPK_3731	COG0195	Participates in both transcription termination and antitermination
YPK_3733	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
YPK_3735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
YPK_3736	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
YPK_3738	COG1534	Rna-binding protein
YPK_3739	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
YPK_3740	COG2027	D-alanyl-D-alanine carboxypeptidase
YPK_3741	COG0745	RESPONSE REGULATOR receiver
YPK_3742	COG0642	Histidine kinase
YPK_3755	COG0697	spore germination
YPK_3758	COG0142	geranyltranstransferase activity
YPK_3760	COG3423	Transcriptional regulator
YPK_3765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
YPK_3767	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
YPK_3768	COG2105	PFAM AIG2 family protein
YPK_3769	COG2911	Protein conserved in bacteria
YPK_3770	COG0729	surface antigen
YPK_3772	COG1253	flavin adenine dinucleotide binding
YPK_3774	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
YPK_3776	COG0737	Belongs to the 5'-nucleotidase family
YPK_3778	COG0545	Peptidyl-prolyl cis-trans isomerase
YPK_3779	COG3061	Opacity-associated protein A
YPK_3782	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
YPK_3784	COG0360	Binds together with S18 to 16S ribosomal RNA
YPK_3786	COG1073	alpha beta
YPK_3787	COG3650	response to hydrogen peroxide
YPK_3788	COG1960	acyl-CoA dehydrogenase activity
YPK_3790	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPK_3791	COG0557	exoribonuclease II activity
YPK_3794	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
YPK_3795	COG0330	HflC and HflK could
YPK_3796	COG0330	HflC and HflK could
YPK_3797	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
YPK_3802	COG0860	N-Acetylmuramoyl-L-alanine amidase
YPK_3803	COG0802	atpase or kinase
YPK_3804	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
YPK_3804	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
YPK_3805	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
YPK_3811	COG3264	Mechanosensitive ion channel
YPK_3811	COG1511	domain protein
YPK_3813	COG1053	succinate dehydrogenase
YPK_3814	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
YPK_3816	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
YPK_3817	COG2076	Multidrug Resistance protein
YPK_3826	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
YPK_3829	COG3383	formate dehydrogenase (NAD+) activity
YPK_3830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPK_3831	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
YPK_3831	COG0493	'glutamate synthase
YPK_3832	COG1309	transcriptional regulator
YPK_3848	COG1454	alcohol dehydrogenase
YPK_3850	COG0629	single-stranded DNA binding
YPK_3851	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
YPK_3852	COG2315	Protein conserved in bacteria
YPK_3853	COG1448	Aminotransferase
YPK_3854	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
YPK_3855	COG0305	Participates in initiation and elongation during chromosome replication
YPK_3858	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
YPK_3859	COG0735	belongs to the Fur family
YPK_3861	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
YPK_3869	COG3121	Chaperone
YPK_3881	COG1358	cellular component organization or biogenesis
YPK_3886	COG3721	Heme iron utilization protein
YPK_3887	COG0702	epimerase
YPK_3889	COG4771	TonB-dependent receptor
YPK_3890	COG3720	iron ion transport
YPK_3891	COG4558	Periplasmic binding protein
YPK_3892	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
YPK_3894	COG0626	cystathionine gamma-synthase activity
YPK_3895	COG0814	amino acid
YPK_3896	COG0583	DNA-binding transcription factor activity
YPK_3897	COG0425	Belongs to the sulfur carrier protein TusA family
YPK_3898	COG2391	methyltransferase activity
YPK_3920	COG1301	dicarboxylic acid transport
YPK_3922	COG3162	membrane
YPK_3925	COG2801	Transposase and inactivated derivatives
YPK_3929	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
YPK_3930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
YPK_3931	COG1739	Uncharacterized protein family UPF0029
YPK_3940	COG0805	protein transport
YPK_3942	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
YPK_3946	COG1322	Protein conserved in bacteria
YPK_3947	COG0586	Pfam SNARE associated Golgi protein
YPK_3948	COG1966	Carbon starvation protein
YPK_3950	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
YPK_3951	COG0412	Dienelactone hydrolase
YPK_3953	COG0583	DNA-binding transcription factor activity
YPK_3957	COG0679	Auxin Efflux Carrier
YPK_3958	COG0584	glycerophosphoryl diester phosphodiesterase
YPK_3970	COG0410	ABC transporter
YPK_3971	COG0411	ABC transporter
YPK_3972	COG4177	L-phenylalanine transmembrane transporter activity
YPK_3973	COG0559	Belongs to the binding-protein-dependent transport system permease family
YPK_3974	COG0683	leucine binding
YPK_3977	COG2177	Part of the ABC transporter FtsEX involved in
YPK_3978	COG2884	Cell division ATP-binding protein ftsE
YPK_3979	COG0552	protein localization to endoplasmic reticulum
YPK_3979	COG0552	protein localization to endoplasmic reticulum
YPK_3980	COG0742	ribosomal rna small subunit methyltransferase
YPK_3981	COG3776	membrane
YPK_3984	COG3714	YhhN family
YPK_3987	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
YPK_3989	COG0247	lactate metabolic process
YPK_3991	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
YPK_3992	COG0584	glycerophosphoryl diester phosphodiesterase
YPK_3994	COG0561	phosphatase activity
YPK_3995	COG2267	carboxylic ester hydrolase activity
YPK_3996	COG1280	lysine exporter protein (LysE YggA)
YPK_3997	COG1280	lysine exporter protein (LysE YggA)
YPK_3998	COG0514	ATP-dependent DNA helicase (RecQ)
YPK_3999	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
YPK_4000	COG2050	protein possibly involved in aromatic compounds catabolism
YPK_4002	COG0598	Magnesium transport protein CorA
YPK_4004	COG5564	TIM-barrel signal transduction protein
YPK_4005	COG5441	Belongs to the UPF0261 family
YPK_4007	COG0210	DNA helicase
YPK_4008	COG1011	Hydrolase
YPK_4009	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
YPK_4010	COG3159	Protein conserved in bacteria
YPK_4012	COG5567	small periplasmic lipoprotein
YPK_4015	COG3072	Adenylate cyclase
YPK_4017	COG1587	Uroporphyrinogen-III synthase
YPK_4018	COG2959	enzyme of heme biosynthesis
YPK_4019	COG3071	HemY protein
YPK_4021	COG1113	amino acid transport
YPK_4025	COG2244	polysaccharide biosynthetic process
YPK_4026	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
YPK_4027	COG0456	acetyltransferase
YPK_4028	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
YPK_4029	COG1088	dTDP-glucose 4,6-dehydratase activity
YPK_4030	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
YPK_4031	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
YPK_4032	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
YPK_4033	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
YPK_4034	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
YPK_4035	COG3118	belongs to the thioredoxin family
YPK_4040	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
YPK_4043	COG3121	Chaperone
YPK_4046	COG3121	Chaperone
YPK_4052	COG0583	DNA-binding transcription factor activity
YPK_4059	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
YPK_4060	COG3978	acetolactate synthase activity
YPK_4063	COG3085	chromosome segregation
YPK_4065	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_4066	COG1172	Belongs to the binding-protein-dependent transport system permease family
YPK_4067	COG1129	ABC transporter
YPK_4068	COG1879	ABC-type sugar transport system periplasmic component
YPK_4080	COG0678	peroxiredoxin activity
YPK_4080	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPK_4081	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
YPK_4086	COG1629	transport
YPK_4094	COG0527	aspartate kinase activity
YPK_4094	COG0460	homoserine dehydrogenase
YPK_4095	COG0626	cystathionine gamma-synthase activity
YPK_4096	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
YPK_4097	COG4682	membrane
YPK_4099	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
YPK_4101	COG1609	Transcriptional regulator
YPK_4102	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
YPK_4105	COG1575	Belongs to the MenA family. Type 1 subfamily
YPK_4112	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
YPK_4113	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
YPK_4114	COG1494	fructose-1,6-bisphosphatase
YPK_4116	COG3152	Membrane
YPK_4119	COG0583	DNA-binding transcription factor activity
YPK_4120	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
YPK_4121	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
YPK_4122	COG0471	metal ion transport
YPK_4125	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
YPK_4131	COG3678	ATP-independent chaperone mediated protein folding
YPK_4132	COG0745	RESPONSE REGULATOR receiver
YPK_4133	COG2205	protein histidine kinase activity
YPK_4134	COG2169	Transcriptional regulator
YPK_4134	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
YPK_4135	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
YPK_4136	COG1045	serine acetyltransferase
YPK_4139	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
YPK_4140	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
YPK_4142	COG4942	peptidase
YPK_4143	COG2861	carbohydrate metabolic process
YPK_4145	COG0156	8-amino-7-oxononanoate synthase activity
YPK_4147	COG0859	PFAM glycosyl transferase family 9
YPK_4148	COG0859	PFAM glycosyl transferase family 9
YPK_4149	COG1519	Transferase
YPK_4153	COG0267	Belongs to the bacterial ribosomal protein bL33 family
YPK_4156	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
YPK_4161	COG1561	YicC-like family, N-terminal region
YPK_4174	COG2860	membrane
YPK_4175	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
YPK_4177	COG1758	RNA polymerase activity
YPK_4178	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
YPK_4179	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
YPK_4180	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
YPK_4181	COG0786	glutamate:sodium symporter activity
YPK_4182	COG2233	PERMEase
YPK_4183	COG2982	Protein involved in outer membrane biogenesis
YPK_4184	COG0456	acetyltransferase
YPK_4187	COG1011	Hydrolase
YPK_4189	COG0174	glutamine synthetase
YPK_4190	COG3852	Histidine kinase
YPK_4192	COG0635	Involved in the biosynthesis of porphyrin-containing compound
YPK_4195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPK_4195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
YPK_4196	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
YPK_4197	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
YPK_4198	COG3084	Protein conserved in bacteria
YPK_4200	COG1763	Mo-molybdopterin cofactor biosynthetic process
YPK_4201	COG3328	transposase activity
YPK_4206	COG2186	Transcriptional regulator
YPK_4207	COG0477	Major facilitator Superfamily
YPK_4209	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
YPK_4215	COG1522	sequence-specific DNA binding
YPK_4216	COG0716	FMN binding
YPK_4219	COG3312	ion transport
YPK_4229	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
YPK_4231	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
YPK_4232	COG0573	inorganic phosphate transmembrane transporter activity
YPK_4233	COG0581	inorganic phosphate transmembrane transporter activity
YPK_4235	COG0704	Plays a role in the regulation of phosphate uptake
YPK_4237	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
YPK_4238	COG0765	amino acid transport
YPK_4239	COG0765	amino acid transport
YPK_4240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
YPK_4241	COG2252	PERMEase
YPK_4246	COG0706	membrane insertase activity
YPK_4249	COG0230	Belongs to the bacterial ribosomal protein bL34 family