locus-tag class description BZ22_1 ENOG4105DM4 PTS System BZ22_1001 ENOG4105CNA YD repeat protein BZ22_1003 ENOG4105CS6 Rhs element vgr protein BZ22_1005 ENOG4107TYG Oxidoreductase domain-containing protein BZ22_1007 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BZ22_1008 ENOG4108RVA ribokinase BZ22_1009 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ22_101 ENOG4105QYV Membrane BZ22_1011 ENOG4105GVF (ABC) transporter BZ22_1013 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BZ22_1016 ENOG4105C7N Xanthine uracil vitamin C permease BZ22_1018 ENOG4105EEQ Na H antiporter BZ22_1020 ENOG4105D1S lipid A biosynthesis BZ22_1022 ENOG4105C2J ABC transporter BZ22_1023 ENOG4105CNN ABC, transporter BZ22_1025 ENOG4105EF1 ribulokinase BZ22_1026 ENOG4105C2X Arabinose 5-phosphate isomerase BZ22_1027 ENOG4105CYM Glutathione S-transferase BZ22_1031 ENOG4105VEQ Cold shock protein BZ22_1032 ENOG4105VEQ Cold shock protein BZ22_1033 ENOG4105VEQ Cold shock protein BZ22_1034 ENOG4108XTF Outer Membrane Lipoprotein BZ22_1037 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BZ22_1038 ENOG4105CSH Transporter BZ22_104 ENOG4105EAH synthase BZ22_1041 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BZ22_1042 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ22_1044 ENOG4108IA2 Sodium pantothenate symporter BZ22_1045 ENOG4105RG0 Membrane BZ22_1047 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BZ22_1048 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BZ22_1052 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family BZ22_1053 ENOG41062P1 Diguanylate cyclase phosphodiesterase BZ22_1054 ENOG4105DFF Rod shape-determining protein mreb BZ22_1055 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BZ22_1056 ENOG4105VQ7 Rod shape-determining protein MreD BZ22_1058 ENOG4105C03 ribonuclease BZ22_1059 ENOG4105QD6 exported protein BZ22_106 ENOG4105HVQ Regulatory factor of maltose metabolism BZ22_1061 ENOG4105D1U peptidase U62 modulator of DNA gyrase BZ22_1070 ENOG4105CR8 Transcriptional regulator BZ22_1076 ENOG4105UNR (Barnase) inhibitor BZ22_1078 ENOG4105CMS peptidase U62, modulator of DNA gyrase BZ22_1080 ENOG4108XVM Cytochrome b(562) BZ22_1081 ENOG4105NXH GreA GreB family elongation factor BZ22_1082 ENOG4105CG3 alpha amylase, catalytic region BZ22_1083 ENOG4105C5Y PTS System BZ22_1084 ENOG4105D4X repressor BZ22_1086 ENOG4105KME endoribonuclease L-psp BZ22_1089 ENOG41080Z8 PHOSPHOCARRIER protein BZ22_1091 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BZ22_1092 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BZ22_1093 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ22_1094 ENOG4108IUZ ABC transporter BZ22_1095 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BZ22_1096 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) BZ22_1097 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BZ22_1098 ENOG4105C2X Arabinose 5-phosphate isomerase BZ22_1099 ENOG4105FEU K -dependent Na -Ca exchanger BZ22_110 ENOG4105DFU Cell wall formation (By similarity) BZ22_1100 ENOG4105DHJ ABC, transporter BZ22_1101 ENOG4105CY3 ABC transporter, permease BZ22_1102 ENOG4107PE3 Mammalian cell entry related domain protein BZ22_1103 ENOG4105E3I toluene tolerance BZ22_1104 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane BZ22_1105 ENOG4105VFK BolA family BZ22_1107 ENOG4105C0H protease BZ22_1108 ENOG4105C0H protease BZ22_1109 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III BZ22_1111 ENOG4105D6Z AFG1 family ATPase BZ22_1114 ENOG4107MKT Stringent starvation protein a BZ22_1115 ENOG4105KB2 stringent starvation protein b BZ22_1117 ENOG4105BZ8 glutamate synthase BZ22_1118 ENOG4105CBC glutamate synthase BZ22_112 ENOG4105F0N pyrophosphate phospho-hydrolase BZ22_1120 ENOG4105N5T Radical SAM Protein BZ22_1122 ENOG4105BZU Histidine kinase BZ22_1123 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BZ22_1125 ENOG4105W4M Transport-associated protein BZ22_1129 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BZ22_113 ENOG4108ZHD aig2 family BZ22_1130 ENOG4108CNN domain protein BZ22_1131 ENOG4105CWB LysR family transcriptional Regulator BZ22_1132 ENOG4105CHF Glutathione S-transferase BZ22_1133 ENOG4108VBZ doxx family BZ22_1135 ENOG41090KG Inner membrane protein YqjE BZ22_1136 ENOG4105NE1 Conserved Protein BZ22_1139 ENOG4106W5V Membrane BZ22_114 ENOG4105MA0 exported protein BZ22_1142 ENOG4105DPW Major facilitator superfamily MFS_1 BZ22_1144 ENOG4107QZW Altronate oxidoreductase BZ22_1145 ENOG4105CTX dehydratase BZ22_1146 ENOG4105P66 Membrane BZ22_1148 ENOG4105EE0 oxidoreductase BZ22_1149 ENOG4108VKG metal-dependent hydrolase BZ22_115 ENOG4105CFU surface antigen BZ22_1152 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ22_1153 ENOG4108YK4 Acid-resistance membrane protein BZ22_1156 ENOG4108M24 von Willebrand factor, type A BZ22_1159 ENOG4108M24 von Willebrand factor, type A BZ22_1160 ENOG4105D5K Hemolysin activator protein BZ22_1161 ENOG4105CKT filamentous hemagglutinin BZ22_1166 ENOG4105CKT filamentous hemagglutinin BZ22_1168 ENOG4105CKT filamentous hemagglutinin BZ22_117 ENOG4105C37 (CBS) domain BZ22_1170 ENOG4105CKT filamentous hemagglutinin BZ22_1175 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 BZ22_1176 ENOG4107KJX Transcriptional regulator BZ22_1177 ENOG4108IJG ABC transporter substrate-binding protein BZ22_1179 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BZ22_118 ENOG41061GZ Protein of unknown function (DUF1107) BZ22_1181 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ22_1183 ENOG4108MI0 Resistance protein BZ22_1184 ENOG4105J12 Multidrug resistance protein mdtN BZ22_1187 ENOG4105CHM Aminotransferase BZ22_119 ENOG4108UUE Transcriptional regulator BZ22_1191 ENOG4105KME endoribonuclease L-psp BZ22_1197 ENOG4105MZU cell filamentation protein BZ22_1198 ENOG4105GMB type VI secretion system effector, hcp1 family BZ22_120 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BZ22_1204 ENOG4105XB7 anti-repressor protein BZ22_121 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BZ22_1221 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ22_1222 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BZ22_1223 ENOG4105VCC 30S ribosomal protein S21 BZ22_1226 ENOG4107ZVW dihydroneopterin aldolase BZ22_1229 ENOG4106MWK domain protein BZ22_123 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ22_1230 ENOG4105I7R Adenylate cyclase BZ22_1233 ENOG4105DVH amino acid BZ22_1234 ENOG4105W0Z cytoplasmic protein BZ22_1236 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BZ22_1237 ENOG4106032 Glutathionylspermidine synthase BZ22_124 ENOG4105FHY Opacity-associated protein A BZ22_1240 ENOG4105DFG type I secretion outer membrane protein BZ22_1241 ENOG41087AY ADP-Ribose pyrophosphatase BZ22_1242 ENOG4108SX3 cytoplasmic protein BZ22_1243 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BZ22_1244 ENOG4105IPS esterase BZ22_1245 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ22_1246 ENOG4105CR8 Transcriptional regulator BZ22_1247 ENOG4105NF4 modulator of drug activity BZ22_1248 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ22_1249 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase BZ22_1250 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) BZ22_1252 ENOG4105CV8 reductase BZ22_1253 ENOG4108I6A alcohol dehydrogenase BZ22_1254 ENOG4105CF7 AraC family transcriptional regulator BZ22_1255 ENOG4108K81 inner membrane protein YghB BZ22_1256 ENOG4105C28 cystathionine BZ22_1257 ENOG4105CWK Biopolymer transport protein, ExbB BZ22_1259 ENOG4108ZZF transport protein (ExbD) BZ22_127 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BZ22_1277 ENOG4108M1A Chitin-binding protein BZ22_1278 ENOG4105E03 chitinase BZ22_128 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BZ22_1280 ENOG4106PG1 outer membrane usher protein BZ22_1281 ENOG4106P2F Pfam:Pili_assembly_C BZ22_1283 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein BZ22_1287 ENOG4105D00 flagellar biosynthetic protein flhB BZ22_1288 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ22_1289 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ22_1290 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ22_1291 ENOG4105DD5 Flagellar motor switch protein BZ22_1293 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ22_1295 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ22_1298 ENOG4108JIR Flagellum-specific ATP synthase BZ22_130 ENOG4108MXZ Esterase BZ22_1302 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA BZ22_1303 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ22_1304 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ22_1305 ENOG4105W00 Flagellar hook capping protein BZ22_1306 ENOG4105BZE flagellar hook protein, FlgE BZ22_1309 ENOG4108M3R transcriptional activator CadC BZ22_131 ENOG4105WSB biofilm stress and motility protein A BZ22_1313 ENOG4107RD7 Flagellar Motor Protein, MotA BZ22_1318 ENOG4108XTF Outer Membrane Lipoprotein BZ22_1319 ENOG4105BZU Histidine kinase BZ22_132 ENOG4105CSU acyl-Coa dehydrogenase BZ22_1320 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ22_1322 ENOG4105BZS acriflavin resistance protein BZ22_1329 ENOG4105CFC Transporter BZ22_133 ENOG4105C2N RNA methyltransferase TrmH family group 3 BZ22_1330 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BZ22_1331 ENOG4107ZSV Receptor BZ22_1332 ENOG4105C0W non-ribosomal peptide synthetase BZ22_1333 ENOG4105C0W non-ribosomal peptide synthetase BZ22_1339 ENOG4105BZ1 (ABC) transporter BZ22_134 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BZ22_1343 ENOG4107EFN gluconate transport system permease 3 BZ22_1345 ENOG4105CS6 Rhs element vgr protein BZ22_1347 ENOG4105CNA YD repeat protein BZ22_1349 ENOG4105CNA YD repeat protein BZ22_1351 ENOG4105CNA YD repeat protein BZ22_1353 ENOG4105CNA YD repeat protein BZ22_1358 ENOG41062WK cellular response to acidity BZ22_1359 ENOG4105C8P )-transporter BZ22_1360 ENOG4105ETE Transcriptional regulator (LacI family BZ22_1362 ENOG4105CT4 transporter BZ22_1364 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ22_1365 ENOG4105DUU IucA IucC family protein BZ22_138 ENOG4105EPW hflc protein BZ22_1382 ENOG4105CDV Ompa motb domain protein BZ22_1384 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ22_139 ENOG4107QJR hflk protein BZ22_1392 ENOG4105CXN decarboxylase BZ22_1393 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ22_1394 ENOG4105C2J ABC transporter BZ22_1395 ENOG4105CNN ABC, transporter BZ22_140 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BZ22_1400 ENOG4105CEN a g-specific adenine glycosylase BZ22_1402 ENOG41090ED Protein with unknown function (DUF469) BZ22_1403 ENOG4105CSV Glutaminase BZ22_1404 ENOG4105K33 Periplasmic Protein BZ22_1405 ENOG4105EUK rtx toxin RtxA BZ22_1406 ENOG4105CSA Coproporphyrinogen iii oxidase BZ22_1407 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BZ22_1409 ENOG4108VIA integral membrane protein BZ22_1410 ENOG4105II7 pyrroline-5-carboxylate reductase BZ22_1411 ENOG4105DFA alanine racemase domain protein BZ22_1412 ENOG4105CZX twitching motility protein BZ22_1414 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) BZ22_1417 ENOG4105D7Z glutathione synthase BZ22_1418 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BZ22_1419 ENOG4105RWS endonuclease I BZ22_1423 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BZ22_1424 ENOG4108RS6 transposase BZ22_1426 ENOG4108RS6 transposase BZ22_1427 ENOG4108K0D peptidase, M48 BZ22_1428 ENOG4105CV1 Transketolase (EC 2.2.1.1) BZ22_1431 ENOG4105D2N Aldolase BZ22_1432 ENOG4105D64 Mechanosensitive ion channel BZ22_1434 ENOG4105MPN Membrane BZ22_1436 ENOG4105E66 phosphoriboisomerase A BZ22_1437 ENOG4108JQ1 Dehydrogenase BZ22_1438 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BZ22_144 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ22_1441 ENOG4107RAQ aminopeptidase BZ22_1442 ENOG4105D0A hydroxylase BZ22_1443 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ22_145 ENOG4105K8N protein family UPF0079, ATPase BZ22_1450 ENOG4108UT2 hemolysin iii BZ22_1453 ENOG4105Y75 tpr repeat protein BZ22_1454 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ22_1455 ENOG4105EB3 Histidine kinase BZ22_1456 ENOG4105CT7 inner membrane cred family protein BZ22_1457 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) BZ22_146 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BZ22_1460 ENOG4105MEH BZ22_1464 ENOG4105DFE Dna adenine methylase BZ22_1468 ENOG4105VZ1 Replication Protein BZ22_147 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BZ22_1472 ENOG4105ED4 portal protein BZ22_1496 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ22_1497 ENOG4105T95 Thiol disulfide interChange protein BZ22_1498 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BZ22_1502 ENOG4105DFP Integrase BZ22_1537 ENOG4105NTW Transcriptional regulator BZ22_1538 ENOG4108UY0 (LipO)protein BZ22_1540 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ22_1541 ENOG4105CNN ABC, transporter BZ22_1544 ENOG4107FKK extracellular solute-binding protein family 1 BZ22_1546 ENOG4105EG2 ABC transporter, permease BZ22_1548 ENOG4105C4C beta-galactosidase BZ22_1549 ENOG4105CI1 PTS System BZ22_155 ENOG4105EGS Mechanosensitive ion channel BZ22_1551 ENOG4105ETE Transcriptional regulator (LacI family BZ22_1553 ENOG4105DPW Major facilitator superfamily MFS_1 BZ22_1554 ENOG4105ETE Transcriptional regulator (LacI family BZ22_1557 ENOG4105D2N Aldolase BZ22_1559 ENOG4105ENH Sulfatase BZ22_1560 ENOG4105C4X radical SAM domain protein BZ22_1562 ENOG4105CHR reductase BZ22_1563 ENOG4105CE4 GlcNAc 6-P deacetylase BZ22_1564 ENOG4108YTN IIa component BZ22_1565 ENOG4105F3R pts system mannose fructose sorbose family iid BZ22_1566 ENOG4105ETZ PTS System BZ22_1567 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB BZ22_1568 ENOG4105E70 isomerase BZ22_1569 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of BZ22_1570 ENOG4105E98 transcriptional regulator DeoR family BZ22_1571 ENOG4105CBG Sulfatase BZ22_1576 ENOG4107B2H carbonic anhydrase BZ22_1580 ENOG4107QHF type ii secretion system protein e BZ22_1581 ENOG4105D7Q type ii secretion system BZ22_1594 ENOG4105C8Q Methyl-accepting chemotaxis BZ22_1596 ENOG4105EJC lysr family transcriptional regulator BZ22_1597 ENOG4105RQF LysR family Transcriptional regulator BZ22_1598 ENOG4105F27 Major Facilitator BZ22_1599 ENOG41060NJ transcriptional regulator BZ22_160 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) BZ22_1600 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BZ22_1606 ENOG4105CPC Aldo Keto reductase BZ22_1609 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BZ22_161 ENOG4105KPY Small multidrug resistance protein BZ22_1616 ENOG4105DSY exodeoxyribonuclease V, gamma BZ22_1617 ENOG4107QXK peptidase BZ22_1618 ENOG4107QKA exodeoxyribonuclease V beta BZ22_1619 ENOG4107QYX exodeoxyribonuclease v alpha BZ22_1621 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ22_1625 ENOG4105CA3 membrane-bound lytic murein transglycosylase BZ22_1626 ENOG4105CUZ uba thif-type nad fad binding protein BZ22_1627 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BZ22_1628 ENOG4105C9B Cysteine desulfurase BZ22_163 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BZ22_1630 ENOG4105ETT transcriptional Regulator, LysR family BZ22_1631 ENOG4105M08 Membrane BZ22_1634 ENOG4105EWT decarboxylase family BZ22_1637 ENOG4105WP7 tRNA pseudouridine synthase C BZ22_1638 ENOG4105DR9 pseudouridine synthase BZ22_1639 ENOG4105QDK Flavodoxin BZ22_164 ENOG4108ZVF (LipO)protein BZ22_1643 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ22_1649 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BZ22_1650 ENOG4105KNE Phosphatidate cytidylyltransferase BZ22_1651 ENOG4105DZP Membrane-associated zinc metalloprotease BZ22_1653 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) BZ22_1657 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BZ22_1659 ENOG4105C0B DNA polymerase III (alpha subunit) BZ22_1661 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BZ22_1664 ENOG4105M1T rho-binding antiterminator BZ22_1666 ENOG4108VWS Yaeq family BZ22_1667 ENOG4108YZN class I peptide chain release factor BZ22_1668 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BZ22_1670 ENOG4108R96 Methyltransferase, YaeB family BZ22_1671 ENOG4108R8X outer membrane lipoprotein BZ22_1672 ENOG4105D01 (LipO)protein BZ22_1673 ENOG4108UMI ABC transporter, permease BZ22_1675 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BZ22_1681 ENOG4105CV8 reductase BZ22_1684 ENOG4105E9H Lytic Murein transglycosylase BZ22_1686 ENOG4105D1A Methyltransferase BZ22_1688 ENOG4108JDX DNA polymerase iii, epsilon subunit BZ22_169 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ22_1690 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BZ22_1692 ENOG4105GIJ Glycine betaine BZ22_1693 ENOG4108HQS Glycine betaine BZ22_1694 ENOG4108IJ7 Glycine betaine BZ22_1695 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ22_1700 ENOG4108WMJ Protein of unknown function (DUF2002) BZ22_1701 ENOG4108SAJ Protein of unknown function (DUF1198) BZ22_1703 ENOG4105VEQ Cold shock protein BZ22_1704 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BZ22_1705 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ22_1706 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ22_1707 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) BZ22_1708 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) BZ22_1715 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) BZ22_1719 ENOG4105XXV Acid-resistance protein BZ22_172 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ22_1720 ENOG4107SVH Potassium channel protein BZ22_1721 ENOG41086WQ Protein CrcB homolog BZ22_1723 ENOG4105VZJ PTS System BZ22_1724 ENOG4105CK1 PTS System BZ22_1725 ENOG4105VCP PTS System BZ22_1726 ENOG4105EZV Transcriptional regulator BZ22_173 ENOG4108RC0 Electron transport protein BZ22_1731 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 BZ22_1734 ENOG4105EEX Two component transcriptional regulator (Winged helix family BZ22_1735 ENOG4105C08 Histidine kinase BZ22_1739 ENOG4105XIQ Protein of unknown function (DUF2517) BZ22_174 ENOG4105BZ8 glutamate synthase BZ22_1740 ENOG4107SEY Conserved Protein BZ22_1741 ENOG4105CVP deoxyribo-dipyrimidine photolyase BZ22_1742 ENOG4107RF4 Phosphodiesterase BZ22_1743 ENOG4107QNR UPF0135 protein BZ22_1745 ENOG4105P4J Allophanate hydrolase, subunit 1 BZ22_1746 ENOG4107R7A Allophanate hydrolase subunit 2 BZ22_175 ENOG4108SIC Transcriptional regulator BZ22_1757 ENOG4105C1J atp-dependent rna helicase BZ22_1759 ENOG4108IYU L-aspartate oxidase BZ22_1761 ENOG41069PW sigma-e factor negative regulatory protein BZ22_1762 ENOG4105VQK sigma E regulatory protein, MucB RseB BZ22_1763 ENOG4105WMJ Positive regulator of sigma E, RseC MucC BZ22_1766 ENOG4105C3F Signal peptidase i BZ22_1770 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) BZ22_1772 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BZ22_1792 ENOG4105HRS Antitermination protein BZ22_18 ENOG4105DZR Type I site-specific deoxyribonuclease BZ22_1826 ENOG4106G6Q Transcriptional regulator BZ22_1828 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB BZ22_1829 ENOG4108Z6B deaminase BZ22_1834 ENOG4107WP9 Histidine kinase BZ22_1835 ENOG4108SKK alpha helix protein BZ22_1836 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ22_1837 ENOG4105C4K Nad synthetase BZ22_1838 ENOG4108YZA Nitrogen regulatory protein pii BZ22_1839 ENOG4108M21 BZ22_1840 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ22_1843 ENOG4108MN2 Stationary phase inducible protein CsiE BZ22_1844 ENOG4105D8G Major Facilitator superfamily BZ22_1845 ENOG41065CD Exported protein BZ22_1846 ENOG4105D7X high-affinity nickel-transporter BZ22_1850 ENOG4105C3J Cysteine desulfurase BZ22_1851 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BZ22_1855 ENOG4108ZIT Ferredoxin, 2FE-2S BZ22_1856 ENOG4105WVQ Fe-S assembly protein IscX BZ22_1858 ENOG4105YYA enhanced serine sensitivity protein SseB BZ22_1859 ENOG4108MGN ATP-binding component of a transport system BZ22_1868 ENOG4105N21 Membrane BZ22_1869 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ22_1872 ENOG4105VPD cellular component movement BZ22_1874 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BZ22_1876 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ22_188 ENOG4105C0A alcohol dehydrogenase BZ22_1889 ENOG4105DWF phosphomethylpyrimidine kinase BZ22_1891 ENOG4108ZGU inhibitor of vertebrate lysozyme BZ22_1893 ENOG4105CFP Peptidase U32 BZ22_1894 ENOG4105KWI UPF0339 protein BZ22_1895 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ22_1896 ENOG4105EB3 Histidine kinase BZ22_190 ENOG4108UUM single-stranded DNA-binding protein BZ22_1901 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ22_1903 ENOG4108JPW Aminotransferase BZ22_1905 ENOG4105F38 ABC transporter, permease BZ22_1906 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BZ22_1908 ENOG4105R8A Heat shock protein BZ22_1909 ENOG4105CJW magnesium transporter BZ22_191 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BZ22_1910 ENOG4105C9X ppx gppa phosphatase BZ22_1911 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BZ22_1912 ENOG4105C8U phosphate abc transporter BZ22_1913 ENOG4105E2Z phosphate ABC transporter (Permease BZ22_1915 ENOG4108C80 FliB family BZ22_1916 ENOG4108MK9 spermidine N(1)-acetyltransferase BZ22_1917 ENOG4108V3E phosphoribosylglycinamide formyltransferase BZ22_192 ENOG4105MSB protein, conserved in bacteria BZ22_1920 ENOG4105C2W permease BZ22_1922 ENOG4105K89 arsenate reductase BZ22_1923 ENOG4105ERG peptidase m48, ste24p BZ22_1924 ENOG4105C02 permease BZ22_1927 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BZ22_1928 ENOG4105RH4 Glycine cleavage system transcriptional repressor BZ22_193 ENOG4105CGF Aromatic amino acid aminotransferase BZ22_1930 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ22_1932 ENOG4105CGZ zinc metallopeptidase BZ22_1938 ENOG4105KUZ arsenate reductase BZ22_194 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ22_1940 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC BZ22_1941 ENOG4107Z33 ABC transporter, permease BZ22_1942 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ22_1943 ENOG4105ENH Sulfatase BZ22_1944 ENOG4105C4X radical SAM domain protein BZ22_1945 ENOG4105S2T inner membrane protein YbcI BZ22_1947 ENOG4105BZS acriflavin resistance protein BZ22_1949 ENOG4105WH1 Two component transcriptional regulator luxr family BZ22_195 ENOG4105CDU Replicative dna helicase BZ22_1950 ENOG4108ZNS ferredoxin-type protein NapF BZ22_1951 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase BZ22_1953 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) BZ22_1954 ENOG4105CUW cytochrome C-TYPE protein BZ22_1956 ENOG4105C6K Malic enzyme BZ22_196 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BZ22_1962 ENOG4105H4F exported protein BZ22_1963 ENOG4105E7K (LipO)protein BZ22_1964 ENOG4105EZR dyp-type peroxidase family protein BZ22_1969 ENOG4108R66 Conserved Protein BZ22_197 ENOG4105P4Z Phage shock protein G BZ22_1970 ENOG4105QEK Transcriptional regulator BZ22_1972 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein BZ22_1973 ENOG4108I5D sulfate abc transporter BZ22_1974 ENOG4105ECW sulfate abc transporter BZ22_1976 ENOG4105C6T cysteine synthase BZ22_1977 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway BZ22_1978 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ22_1979 ENOG41062D9 Histidine kinase BZ22_198 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ22_1981 ENOG4105C87 Aminotransferase class I and II BZ22_1982 ENOG4107RAQ aminopeptidase BZ22_1984 ENOG4105E1V na solute symporter BZ22_1987 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ22_1988 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ22_1989 ENOG4105E0F Histidine kinase BZ22_199 ENOG4105MYN Zinc uptake regulation protein BZ22_1990 ENOG4105C5Y PTS System BZ22_1992 ENOG4105KZ7 phosphocarrier protein hpr BZ22_1993 ENOG4105C6T cysteine synthase BZ22_1994 ENOG4105EXN Sulfate transport protein CysZ BZ22_1997 ENOG4105VRT cytoplasmic protein BZ22_2 ENOG4108YRF PTS System BZ22_2008 ENOG4105D9N nucleoside BZ22_201 ENOG41080IJ Diacylglycerol kinase BZ22_2011 ENOG4105CPC Aldo Keto reductase BZ22_2012 ENOG4105C5Q Transcriptional regulator BZ22_2015 ENOG41072TH Protein of unknown function (DUF1479) BZ22_2016 ENOG4105CHM Aminotransferase BZ22_2017 ENOG4108VKM cytochrome b561 BZ22_2019 ENOG4106B0W Curli production assembly transport component CsgG BZ22_2021 ENOG4107Y60 (LipO)protein BZ22_2023 ENOG4108NEM leader-binding protein dmsD BZ22_2024 ENOG4107KGK dmso reductase anchor subunit BZ22_2025 ENOG4105QAX Iron-sulfur BZ22_2026 ENOG4107QY8 reductase BZ22_2028 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ22_2034 ENOG4105CVE Lytic murein transglycosylase BZ22_2044 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ22_2046 ENOG4105GQR Chaperone BZ22_2047 ENOG4105CW0 outer membrane usher protein BZ22_2056 ENOG4105CS6 Rhs element vgr protein BZ22_2062 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BZ22_2064 ENOG4108V0P LemA family BZ22_2068 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BZ22_2069 ENOG41060IM Heme exporter protein BZ22_2070 ENOG4105X3C heme exporter protein BZ22_2072 ENOG4105DA4 cytochrome c-type biogenesis protein BZ22_2073 ENOG4107QX9 Thiol disulfide interChange protein BZ22_2074 ENOG4105KWW Biogenesis protein BZ22_2075 ENOG4105KWW Biogenesis protein BZ22_2076 ENOG410903C (LipO)protein BZ22_2077 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BZ22_2078 ENOG4105KZW UPF0381 protein BZ22_208 ENOG4108S1B Periplasmic chaperone protein BZ22_2081 ENOG4108BY2 phosphohistidine phosphatase BZ22_2083 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BZ22_2086 ENOG4105EJ9 Membrane BZ22_2087 ENOG4108BPE -transporting atpase BZ22_2088 ENOG4105MH2 YfcL protein BZ22_2090 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ22_2093 ENOG4106WZ1 flagella biosynthesis regulator BZ22_2094 ENOG410631K Membrane BZ22_2097 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ22_2099 ENOG4105DQR SNARE associated Golgi BZ22_21 ENOG4108K5H permease YjgP YjgQ family protein BZ22_2101 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BZ22_2102 ENOG4108S3P Sporulation domain protein BZ22_2103 ENOG4105E96 Colicin v production protein BZ22_2104 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BZ22_2105 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BZ22_2106 ENOG4105E89 ABC transporter BZ22_2107 ENOG4105DSP amino acid AbC transporter BZ22_2108 ENOG4106YG3 ABC transporter BZ22_2109 ENOG4108JEH abc transporter atp-binding protein BZ22_2110 ENOG4105ECP epimerase BZ22_2112 ENOG4108RE9 Phosphodiesterase BZ22_2113 ENOG4105PTV Nudix Hydrolase BZ22_2114 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BZ22_2117 ENOG4107P2S Transcriptional regulator BZ22_2118 ENOG4105C6K Malic enzyme BZ22_2122 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 BZ22_2123 ENOG4107QWE )-transporter BZ22_2126 ENOG4105CHM Aminotransferase BZ22_2127 ENOG4107NQ8 LysR family Transcriptional regulator BZ22_2129 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BZ22_2131 ENOG4105GKE subunit e BZ22_2132 ENOG4107QIZ NADH dehydrogenase BZ22_2133 ENOG4108IEH NADH dehydrogenase subunit g BZ22_2136 ENOG4107UFS subunit j BZ22_2138 ENOG4105D65 subunit l BZ22_2139 ENOG4105C8S subunit m BZ22_2142 ENOG4108R66 Conserved Protein BZ22_2143 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ22_2144 ENOG4105CHR reductase BZ22_2145 ENOG4105F32 YngK protein BZ22_2146 ENOG4105K2J Transcriptional regulator BZ22_2147 ENOG4105C5I Dehydrogenase BZ22_2150 ENOG4105C01 Dihydroxy-acid dehydratase BZ22_2152 ENOG4105TNS Conserved Protein BZ22_2154 ENOG4105E4F Isochorismate synthase BZ22_2157 ENOG4108IPT Naphthoate synthase BZ22_2159 ENOG4105CEY Amp-dependent synthetase and ligase BZ22_2160 ENOG4108MTB glycosyl transferase family BZ22_2161 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction BZ22_2163 ENOG4107SDU Methyl-accepting chemotaxis BZ22_2164 ENOG4105CDA abc transporter atp-binding protein BZ22_2165 ENOG4105E5Q amino acid AbC transporter BZ22_2166 ENOG4107R0W ABC transporter BZ22_2172 ENOG4108T1M outer membrane protein x BZ22_2176 ENOG4105CPQ Dehydrogenase BZ22_2177 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ22_2178 ENOG4105C2J ABC transporter BZ22_2179 ENOG4105CNN ABC, transporter BZ22_2180 ENOG4105FKQ transcriptional regulator BZ22_2181 ENOG4105EJC lysr family transcriptional regulator BZ22_2182 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BZ22_2183 ENOG4105C94 Transporter BZ22_2184 ENOG4105DVW rieske (2Fe-2S) BZ22_2185 ENOG4105E3J oxidoreductase BZ22_2186 ENOG4105D5K Hemolysin activator protein BZ22_2187 ENOG4105CKT filamentous hemagglutinin BZ22_2190 ENOG4105CKT filamentous hemagglutinin BZ22_2193 ENOG4105TIV Cryptic phage CTXphi transcriptional repressor RstR BZ22_2194 ENOG4105CKT filamentous hemagglutinin BZ22_2196 ENOG4108IJ9 (ABC) transporter BZ22_2198 ENOG4105ETE Transcriptional regulator (LacI family BZ22_22 ENOG4108M8S permease YjgP YjgQ family protein BZ22_220 ENOG4105DAX Pfam:DUF2983 BZ22_2201 ENOG4105DRS transport system, permease BZ22_2202 ENOG4105HY2 Glycosidase related protein BZ22_2206 ENOG4105CUY Mechanosensitive ion channel BZ22_2209 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) BZ22_2210 ENOG4107IIZ CRISPR-associated helicase, Cas3 BZ22_2211 ENOG4105ENG CRISPR-associated protein, Csy1 family BZ22_2212 ENOG4105DZX CRISPR-associated protein, Csy2 family BZ22_2213 ENOG4105M6W Crispr-associated protein, Csy3 family BZ22_2214 ENOG4108Y1S CRISPR-associated protein, Csy4 family BZ22_2215 ENOG4105CPC Aldo Keto reductase BZ22_2217 ENOG4105C54 Major Facilitator superfamily BZ22_2219 ENOG4105ETT transcriptional Regulator, LysR family BZ22_2220 ENOG4107YC3 synthase BZ22_2221 ENOG4105VJY transcriptional regulator BZ22_2225 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) BZ22_2226 ENOG4105DJ9 glucan biosynthesis protein BZ22_2227 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) BZ22_2228 ENOG4105NAC (LipO)protein BZ22_2229 ENOG4105DUX Transporter BZ22_2230 ENOG4105D1S lipid A biosynthesis BZ22_2233 ENOG4105DSF transport protein BZ22_2236 ENOG4105PVA Biofilm formation regulatory protein BssS BZ22_2239 ENOG41067V3 Antibiotic biosynthesis monooxygenase BZ22_224 ENOG4105D4P Coproporphyrinogen iii oxidase BZ22_2240 ENOG4107QQB Ribonuclease E BZ22_2241 ENOG4105EI2 Pseudouridine synthase BZ22_2242 ENOG4108RS6 transposase BZ22_2244 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BZ22_2245 ENOG4105VGS 50s ribosomal protein l32 BZ22_2248 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ22_2249 ENOG4105CHR reductase BZ22_225 ENOG41090JE Utilization Protein BZ22_2251 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ22_2252 ENOG4105YAZ 4-amino-4-deoxychorismate lyase BZ22_2253 ENOG4105HHA aminodeoxychorismate lyase BZ22_2255 ENOG4107QRG dna polymerase iii BZ22_2256 ENOG4105F8V Hydrolase, tatD family BZ22_2257 ENOG4105CI1 PTS System BZ22_2258 ENOG4105F9E Shikimate 5-dehydrogenase BZ22_2259 ENOG4105K59 histidine triad (HIT) protein BZ22_2260 ENOG41090DQ Lipoprotein BZ22_2265 ENOG4105CEP NADH dehydrogenase BZ22_2268 ENOG4107MBR 17 kDa surface antigen BZ22_2269 ENOG4108JA2 transcriptioN-repair coupling factor BZ22_227 ENOG4107F3C Hemin uptake protein BZ22_2270 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ22_2272 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ22_2274 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BZ22_2276 ENOG4105EZE Cupin 4 family protein BZ22_2278 ENOG4105XJC Two component transcriptional regulator (Winged helix family BZ22_228 ENOG4107ENK receptor BZ22_2280 ENOG4107QTF adenylosuccinate lyase BZ22_2284 ENOG4108R99 pseudouridine synthase BZ22_2285 ENOG4108HMX isocitrate dehydrogenase (NADP) BZ22_2286 ENOG4106NDP Transcriptional regulator BZ22_2288 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BZ22_2289 ENOG4105ECR NmrA family BZ22_229 ENOG4106QJH hemin transport protein BZ22_2290 ENOG4105KVH Transcriptional regulator BZ22_2292 ENOG4105D6F Phosphatase BZ22_2293 ENOG41061EV selenium-binding protein YdfZ BZ22_2295 ENOG4108XM1 transcriptional regulator AsnC family BZ22_2297 ENOG4105GSJ Inner membrane protein ylaC BZ22_230 ENOG4107R4I Periplasmic binding protein BZ22_2300 ENOG4105VEQ Cold shock protein BZ22_2302 ENOG4105C8Q Methyl-accepting chemotaxis BZ22_2303 ENOG4105KT7 mgtC SapB transporter BZ22_2304 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BZ22_2306 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region BZ22_2307 ENOG4107RD7 Flagellar Motor Protein, MotA BZ22_2308 ENOG4105ER2 Ompa motb domain protein BZ22_2309 ENOG4105CBS Chea signal transduction histidine kinase BZ22_231 ENOG4105EHG Permease protein BZ22_2310 ENOG4108V3W Chemotaxis protein, CheW BZ22_2313 ENOG4105C8Q Methyl-accepting chemotaxis BZ22_2316 ENOG4105BZU Histidine kinase BZ22_2318 ENOG4108VYJ response regulator receiver protein BZ22_2319 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) BZ22_2320 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ22_2324 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ22_233 ENOG4105C28 cystathionine BZ22_2331 ENOG4105WT8 Protein of unknown function (DUF1480) BZ22_2334 ENOG4105GQR Chaperone BZ22_2338 ENOG4105DY2 Paraquat-inducible protein b BZ22_2339 ENOG4105H2K paraquat-inducible protein a BZ22_234 ENOG4105C44 Serine transporter BZ22_2340 ENOG4108ZGC gaf domain protein BZ22_2342 ENOG4105CN1 protease BZ22_2345 ENOG4105H8W Fimbrial protein BZ22_2346 ENOG4108VEV chaperone BZ22_2349 ENOG4108VEV chaperone BZ22_235 ENOG4105EQ2 LysR family Transcriptional regulator BZ22_2350 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ22_2351 ENOG4105CAZ oligogalacturonide lyase BZ22_2353 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ22_2354 ENOG4108ETY sodium dicarboxylate symporter BZ22_2355 ENOG4107K5X Membrane-bound metal-dependent hydrolase BZ22_2356 ENOG4108PU9 oligogalacturonate-specific porin BZ22_2357 ENOG4105WEM extracellular solute-binding protein BZ22_2359 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BZ22_236 ENOG4105KSU Redox protein BZ22_2360 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BZ22_2361 ENOG41061NF Pectate lyase BZ22_2362 ENOG4105CHR reductase BZ22_2364 ENOG4105M5J Cupin 2, conserved barrel domain protein BZ22_2367 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 BZ22_2368 ENOG4107PN8 YfeABCD locus regulator BZ22_2369 ENOG4105FGM Fructosamine kinase BZ22_237 ENOG41066VF YeeE YedE family protein BZ22_2370 ENOG4105CC5 ABC transporter BZ22_2371 ENOG4105CC5 ABC transporter BZ22_2372 ENOG4105DIK (ABC) transporter BZ22_2373 ENOG4105DSE periplasmic solute binding protein BZ22_2377 ENOG41087WU BZ22_238 ENOG4108IUF type iii secretion BZ22_2384 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BZ22_2387 ENOG4108V06 Glutathione peroxidase BZ22_2388 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) BZ22_239 ENOG4108TN6 type iii secretion BZ22_2396 ENOG4108QBX (LipO)protein BZ22_2399 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ22_24 ENOG4105MYG DNA polymerase iii, chi subunit BZ22_240 ENOG41083GP type iii secretion BZ22_2401 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BZ22_2402 ENOG4105IPI Membrane BZ22_2403 ENOG4105CQB FAD linked oxidase domain protein BZ22_2404 ENOG4105KA0 thioesterase Superfamily protein BZ22_2405 ENOG4108Z4V iron-sulfur cluster assembly BZ22_2406 ENOG4105DIW FeS assembly protein SUFB BZ22_2407 ENOG4105C3K feS assembly ATPase SufC BZ22_2408 ENOG4105JRK feS assembly protein SufD BZ22_241 ENOG4108HHI Type III secretion system protein BZ22_2411 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BZ22_2412 ENOG4105KMX major outer membrane lipoprotein BZ22_2413 ENOG4105CA9 Pyruvate kinase BZ22_2418 ENOG4108R6K riboflavin synthase, subunit alpha BZ22_2419 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BZ22_2420 ENOG4105CZQ inner membrane transport protein YdhC BZ22_2422 ENOG4105F52 Transcriptional regulator BZ22_2425 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ22_2426 ENOG4105K4H Nlp p60 protein BZ22_2428 ENOG4105M2J Glutaredoxin BZ22_2430 ENOG4108UYE Lactoylglutathione lyase BZ22_2432 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ22_2433 ENOG4108WUH Transcriptional regulator, TetR family BZ22_2434 ENOG4105DIJ Phosphoethanolamine transferase BZ22_2435 ENOG4105XZD Fe-S protein BZ22_2436 ENOG4107RGM aldo keto reductase BZ22_2438 ENOG4108XTF Outer Membrane Lipoprotein BZ22_2440 ENOG410642K Lysozyme inhibitor BZ22_2444 ENOG4108K3A Glutathione S-transferase BZ22_2445 ENOG4108ZR5 Conserved Protein BZ22_2446 ENOG41069YE inner membrane protein yohC BZ22_2447 ENOG4105DUX Transporter BZ22_2448 ENOG4105Q4T oxidoreductase BZ22_2449 ENOG4108JQ2 peptide transport system atp-binding protein BZ22_245 ENOG4108JIR Flagellum-specific ATP synthase BZ22_2450 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein BZ22_2451 ENOG4108EU3 peptide transport system, permease BZ22_2452 ENOG4108I5W peptide transport system, permease protein BZ22_2453 ENOG4108HIY periplasmic BZ22_2454 ENOG4105E51 psp operon transcriptional activator BZ22_2455 ENOG41087YS Phage shock protein A BZ22_2456 ENOG4105YYT phage shock protein B BZ22_2457 ENOG4105FM1 phage shock protein C BZ22_2459 ENOG4105CM6 amino acid regulated cytosolic protein BZ22_2464 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BZ22_2465 ENOG4107S8C mandelate racemase muconate lactonizing BZ22_2466 ENOG4105KXI murein peptide amidase A BZ22_2467 ENOG4107QSI ABC, transporter BZ22_2473 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) BZ22_2475 ENOG4105KT7 mgtC SapB transporter BZ22_2477 ENOG41090X5 Heat shock protein hslJ BZ22_2478 ENOG4105C5I Dehydrogenase BZ22_2479 ENOG4107H52 Dicarboxylate transport BZ22_2480 ENOG410689M (LipO)protein BZ22_2481 ENOG4105WXT Conserved Protein BZ22_2482 ENOG4105DEI Mannitol dehydrogenase BZ22_2483 ENOG4105DKT Transcriptional regulator BZ22_2485 ENOG4105CQ7 ATP-dependent helicase BZ22_2488 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap BZ22_2490 ENOG4105DS1 cytochrome b561 BZ22_2494 ENOG4105CTD carboxy-peptidase BZ22_2495 ENOG4105JJR Histidine kinase BZ22_2496 ENOG4107EXC regulatoR BZ22_2498 ENOG4105D5Q Arginine ornithine antiporter BZ22_2499 ENOG4105C5D exported protein BZ22_2500 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ22_2501 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ22_2502 ENOG4105Q9Y Universal stress protein BZ22_2503 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BZ22_2504 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ22_2507 ENOG4105PAD Hydrolase BZ22_2508 ENOG4105M71 acetolactate synthase 1 regulatory subunit BZ22_2509 ENOG4105C7K acetolactate synthase BZ22_2514 ENOG4105FYV Amp nucleosidase BZ22_2516 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ22_2517 ENOG4107UWC ABC, transporter BZ22_2519 ENOG4105C2J ABC transporter BZ22_2520 ENOG4105CNN ABC, transporter BZ22_2521 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ22_2523 ENOG41060NJ transcriptional regulator BZ22_2524 ENOG4105DFD Na H antiporter BZ22_2525 ENOG4105C87 Aminotransferase class I and II BZ22_2527 ENOG4105D13 transposase BZ22_2529 ENOG4105DWP Membrane BZ22_2531 ENOG4105C26 Dehydrogenase BZ22_2532 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BZ22_2533 ENOG4105EMU Dehydrogenase BZ22_2535 ENOG4105KBG Protein of unknown function (DUF1161) BZ22_2537 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ22_2539 ENOG4105DAG ROK family BZ22_2540 ENOG4106NZI LysR family Transcriptional regulator BZ22_2541 ENOG4105D94 Major Facilitator Superfamily BZ22_2543 ENOG4105C9Q fumarate hydratase class II BZ22_2544 ENOG4105EIP mannose-6-phosphate isomerase BZ22_2545 ENOG4106J39 exported protein BZ22_2546 ENOG4105FDP GntR family transcriptional regulator BZ22_2547 ENOG4105CI1 PTS System BZ22_2552 ENOG4105DHU Bile acid BZ22_2553 ENOG4105D9R oxidoreductase BZ22_2555 ENOG4105CNN ABC, transporter BZ22_2557 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator BZ22_2561 ENOG4108JJA ABC, transporter BZ22_2563 ENOG4108JJA ABC, transporter BZ22_2564 ENOG4105M9B inner membrane protein ydgK BZ22_2568 ENOG4105UEI Transcriptional Regulator AraC Family BZ22_257 ENOG4105BZU Histidine kinase BZ22_2570 ENOG4108UQQ Electron transport complex BZ22_2572 ENOG4105CSM endonuclease III BZ22_2573 ENOG4105EXW epimerase dehydratase BZ22_2574 ENOG4105CSP Major Facilitator Superfamily BZ22_2576 ENOG4105D22 carbon starvation protein BZ22_2577 ENOG4105VCD cytoplasmic protein BZ22_2578 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BZ22_258 ENOG4105WH1 Two component transcriptional regulator luxr family BZ22_2580 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ22_2581 ENOG41061RM osmotically inducible lipoprotein BZ22_2582 ENOG4108ZJT translation initiation factor, Sui1 BZ22_2585 ENOG4105CFV Tetratricopeptide repeat protein BZ22_2586 ENOG4105Q4A inner membrane protein yciS BZ22_2587 ENOG4105EYK Phosphatidylglycerophosphatase B BZ22_2588 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BZ22_2589 ENOG4107QM5 aconitate hydratase BZ22_259 ENOG4105CK2 sodium dicarboxylate symporter BZ22_2591 ENOG4107R11 Transcriptional regulator BZ22_2592 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ22_2594 ENOG4105RKX Protein of unknown function (DUF2498) BZ22_2595 ENOG4105ERU peptidase BZ22_2596 ENOG4105UBK short-chain dehydrogenase reductase BZ22_2597 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BZ22_2598 ENOG4105FE9 pseudouridine synthase BZ22_2599 ENOG4107RTD sua5 ycio yrdc ywlc family protein BZ22_26 ENOG4108MJ3 acetyltransferase BZ22_2600 ENOG4105DB7 PHP domain protein BZ22_2602 ENOG4105DDQ anthranilate synthase BZ22_2604 ENOG4105DK0 Indole-3-glycerol phosphate synthase BZ22_2608 ENOG4105EIF outer membrane protein W BZ22_261 ENOG41062QD Membrane BZ22_2612 ENOG4105NAU thioesterase Superfamily protein BZ22_2613 ENOG410822N TonB family BZ22_2615 ENOG4105K9H YciI-like protein BZ22_2618 ENOG4108T1M outer membrane protein x BZ22_2622 ENOG4108JQ7 (ABC) transporter BZ22_2623 ENOG4105C3U ABC transporter BZ22_2624 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ22_2626 ENOG4107QSI ABC, transporter BZ22_2627 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BZ22_2628 ENOG4108EKI Dehydrogenase BZ22_2629 ENOG4107104 thymidine kinase BZ22_2631 ENOG4105C6Y Udp-glucose 6-dehydrogenase BZ22_2632 ENOG4105I93 response regulator BZ22_2634 ENOG4105CIY formyltetrahydrofolate deformylase BZ22_2637 ENOG4105SKE transcriptional Regulator LysR family BZ22_2638 ENOG4105CGK Exodeoxyribonuclease III BZ22_2639 ENOG4105M6F mutator MutT protein BZ22_264 ENOG4105CMM transposase BZ22_2640 ENOG4105MTM Protein of unknown function (DUF1496) BZ22_2641 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ22_2643 ENOG41069NU Nitroreductase BZ22_2644 ENOG4105D07 Signal peptide peptidase, SppA BZ22_2645 ENOG4105HDK L-asparaginase BZ22_2646 ENOG4108RWI nicotinamidase BZ22_2647 ENOG4105VUT cytoplasmic protein BZ22_2650 ENOG4105DSB aldose 1-epimerase BZ22_2651 ENOG4105GNX MltA-interacting MipA family protein BZ22_2652 ENOG4105CYN Serine protein kinase BZ22_2655 ENOG4105HEI LysR family (Transcriptional regulator BZ22_2656 ENOG4105EUB pirin domain protein BZ22_2657 ENOG4105CNH Multidrug resistance protein MdtL BZ22_2659 ENOG4105ED1 spovr family BZ22_2665 ENOG4105C3J Cysteine desulfurase BZ22_2668 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BZ22_2669 ENOG4105CVE Lytic murein transglycosylase BZ22_2672 ENOG4107QMS site-determining protein BZ22_2673 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) BZ22_2674 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BZ22_2675 ENOG4105CEY Amp-dependent synthetase and ligase BZ22_2676 ENOG4105Y4Z Outer Membrane Lipoprotein BZ22_2677 ENOG41072GX Peptidase M22 Glycoprotease BZ22_2678 ENOG4105DVT helicase BZ22_2679 ENOG4105M4H endoribonuclease L-psp BZ22_2682 ENOG4108UHU Aldolase BZ22_2684 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BZ22_2685 ENOG4106KNT transcriptional regulator BZ22_2686 ENOG4105CA9 Pyruvate kinase BZ22_2687 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BZ22_2688 ENOG4105DR5 peptidase BZ22_2689 ENOG4105NXV High-affinity zinc uptake system protein BZ22_2691 ENOG4105FAV ABC, transporter BZ22_2696 ENOG4108TIT dATP pyrophosphohydrolase BZ22_2698 ENOG41081XQ Conserved Protein BZ22_2699 ENOG4105WJG Glutathione BZ22_27 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) BZ22_2703 ENOG4106ZCM YecM protein BZ22_2707 ENOG4105CJR Integral membrane protein (MviN BZ22_271 ENOG4108RR8 protoporphyrinogen oxidase BZ22_2710 ENOG4105D9U N-acetyltransferase BZ22_2712 ENOG4105F3T (LipO)protein BZ22_2713 ENOG4107XHZ cytoplasmic chaperone TorD family protein BZ22_2716 ENOG4105E2R ROK family BZ22_2717 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BZ22_2719 ENOG4105F38 ABC transporter, permease BZ22_272 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BZ22_2720 ENOG4105EG2 ABC transporter, permease BZ22_2725 ENOG4105CHH sulfate transporter BZ22_2727 ENOG41063JG Transcriptional regulator BZ22_2728 ENOG4108YY7 Invasion gene expression up-regulator SirB BZ22_2729 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BZ22_273 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BZ22_2734 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BZ22_2735 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria BZ22_2737 ENOG4105C3G gtp-binding protein BZ22_2741 ENOG4105ENX hydrolase BZ22_2743 ENOG4105GR3 Histidine kinase BZ22_2752 ENOG4108WF3 methyltransferase BZ22_2765 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ22_2766 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BZ22_2768 ENOG41090B9 response to stress BZ22_2769 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BZ22_277 ENOG4107QK7 reductase BZ22_2770 ENOG4105CZE histidine utilization repressor BZ22_2781 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BZ22_2782 ENOG4105BZU Histidine kinase BZ22_2783 ENOG4105EWV Sodium calcium exchanger membrane region BZ22_2784 ENOG4108RS6 transposase BZ22_2785 ENOG4105D5M phosphate starvation-inducible protein BZ22_2788 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD BZ22_2789 ENOG4105CND Glycosyl transferase, family 2 BZ22_279 ENOG4105MDZ Transcriptional activator rfaH BZ22_2790 ENOG4107BJW polysaccharide deacetylase BZ22_2791 ENOG4108TUY outer membrane protein PgaA BZ22_2792 ENOG4105H1N peptidase, M24 BZ22_2796 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BZ22_2798 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BZ22_280 ENOG4105D52 delta-aminolevulinic acid dehydratase BZ22_2801 ENOG4107SJW iron permease, FTR1 BZ22_2803 ENOG4105CSV Glutaminase BZ22_2804 ENOG4105MVE transcriptional regulator BZ22_2805 ENOG4105C85 amino acid BZ22_2806 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BZ22_2807 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ22_2816 ENOG4105DJG MaoC domain protein dehydratase BZ22_2817 ENOG4105CYC Transferase BZ22_2818 ENOG4108Q9V regulatoR BZ22_282 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BZ22_2823 ENOG4105CW0 outer membrane usher protein BZ22_2825 ENOG4108MQF Chaperone BZ22_2827 ENOG4108IJ9 (ABC) transporter BZ22_2828 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BZ22_2831 ENOG4105DRI Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity) BZ22_2833 ENOG4105FDP GntR family transcriptional regulator BZ22_284 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BZ22_2854 ENOG4105ZTC transcriptional activator, Ogr delta BZ22_2855 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ22_286 ENOG4105JC1 sterol-binding domain protein BZ22_2867 ENOG4108IRC dna polymerase iii BZ22_2868 ENOG4105DFE Dna adenine methylase BZ22_2870 ENOG4105VZ1 Replication Protein BZ22_2873 ENOG4105ED4 portal protein BZ22_288 ENOG4105CGY Dna recombination protein BZ22_289 ENOG4108KF1 Membrane BZ22_29 ENOG4105XEP YhcH YjgK YiaL family protein BZ22_2901 ENOG4105ZTC transcriptional activator, Ogr delta BZ22_2907 ENOG4105WH1 Two component transcriptional regulator luxr family BZ22_2908 ENOG4105XVG cytoplasmic protein BZ22_2909 ENOG4105RA2 Membrane BZ22_2911 ENOG4108T1M outer membrane protein x BZ22_2913 ENOG4105C85 amino acid BZ22_2919 ENOG4105CK7 Sodium proline symporter BZ22_292 ENOG4108I5U Uridine phosphorylase BZ22_2921 ENOG4105C26 Dehydrogenase BZ22_2924 ENOG4105CDA abc transporter atp-binding protein BZ22_2925 ENOG4105E5Q amino acid AbC transporter BZ22_2926 ENOG4105EAB amino acid AbC transporter BZ22_2928 ENOG4108M9K flagella biosynthesis protein FliZ BZ22_2929 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ22_293 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) BZ22_2930 ENOG4105I03 Flagellin BZ22_2931 ENOG4105DTS flagellar hook-associated BZ22_2932 ENOG4105MQ3 flagellar protein FliS BZ22_2935 ENOG4105DHT Metal Dependent Phosphohydrolase BZ22_2939 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BZ22_2940 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ22_2941 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ22_2942 ENOG41090PJ Flagellar assembly protein BZ22_2943 ENOG4108JIR Flagellum-specific ATP synthase BZ22_2944 ENOG4105GSA Flagellar export protein flij BZ22_2945 ENOG4105WF4 Flagellar hook-length control protein BZ22_2946 ENOG4107ZI8 flagellar basal body-associated protein flil BZ22_2947 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ22_2948 ENOG4105DD5 Flagellar motor switch protein BZ22_295 ENOG4105EMK carboxylate amino acid amine transporter BZ22_2950 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ22_2951 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ22_2952 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ22_2955 ENOG4108MGF sugar kinase BZ22_2956 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BZ22_2957 ENOG4105C2J ABC transporter BZ22_2959 ENOG4105CNN ABC, transporter BZ22_296 ENOG4105DZ2 Transcriptional regulator BZ22_2962 ENOG4105DKT Transcriptional regulator BZ22_2963 ENOG4105DTJ flagellar hook-associated protein BZ22_2964 ENOG4105E1Q flagellar hook-associated protein BZ22_2965 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BZ22_2968 ENOG4105CGA flagellar basal-body rod protein FlgG BZ22_2969 ENOG4108KPB Flagellar basal-body rod protein FlgF BZ22_2970 ENOG4105BZE flagellar hook protein, FlgE BZ22_2971 ENOG4105W00 Flagellar hook capping protein BZ22_2972 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ22_2973 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ22_2974 ENOG4105CKS Flagella basal body P-ring formation protein flgA BZ22_2975 ENOG4105M9M anti-sigma28 factor FlgM BZ22_2976 ENOG4105QVD Flagella synthesis protein FlgN BZ22_2978 ENOG4105W13 flagellar protein BZ22_2979 ENOG4105D7B Flagellar biosynthesis protein flha BZ22_2980 ENOG4105D00 flagellar biosynthetic protein flhB BZ22_2983 ENOG4105NKT exported protein BZ22_2985 ENOG4105FXM Copper resistance protein BZ22_2986 ENOG41090A1 ferritin BZ22_2987 ENOG4105MPK DNA polymerase III subunit theta BZ22_2989 ENOG4105CUG Oligopeptidase b BZ22_299 ENOG4105RK9 auxin efflux carrier BZ22_2992 ENOG4105X2V dna damage-inducible protein BZ22_2993 ENOG4105C1J atp-dependent rna helicase BZ22_2996 ENOG4105CRQ synthase (Component I) BZ22_2998 ENOG4105EJQ L-serine dehydratase BZ22_2999 ENOG4107UWN reductase BZ22_3 ENOG4106R3P AraC family transcriptional regulator BZ22_300 ENOG4107T6V glycerophosphoryl diester phosphodiesterase BZ22_3000 ENOG4105EFA 4-hydroxyphenylacetate BZ22_3005 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase BZ22_3006 ENOG4105C26 Dehydrogenase BZ22_3009 ENOG4108V8F Transcriptional regulator, MarR family BZ22_3010 ENOG4105EE5 Membrane protein terC BZ22_3011 ENOG4108EQA pts system BZ22_3012 ENOG4105ETZ PTS System BZ22_3013 ENOG4105F3R pts system mannose fructose sorbose family iid BZ22_3017 ENOG4105BZU Histidine kinase BZ22_3019 ENOG4105DHI Methyltransferase BZ22_3020 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ22_3021 ENOG4105VEQ Cold shock protein BZ22_3024 ENOG4105C85 amino acid BZ22_3027 ENOG41064PC BZ22_3028 ENOG4105TIK BZ22_3029 ENOG4105N4N Protein of unknown function (DUF2766) BZ22_3033 ENOG4105BZ1 (ABC) transporter BZ22_3039 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BZ22_3043 ENOG4108TSE Transferase BZ22_3044 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BZ22_3046 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BZ22_3047 ENOG4108KX4 response regulator BZ22_3049 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BZ22_3053 ENOG4105UQX Mate efflux family protein BZ22_3056 ENOG4105DIA mandelate racemase muconate lactonizing BZ22_3058 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BZ22_3059 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BZ22_3060 ENOG4105CSP Major Facilitator Superfamily BZ22_3061 ENOG4105TNG K13735 adhesin invasin BZ22_3064 ENOG4105CJB Exodeoxyribonuclease I BZ22_3065 ENOG4105CUB amino acid BZ22_3067 ENOG4107SCQ Iron-containing alcohol dehydrogenase BZ22_3068 ENOG4105C2J ABC transporter BZ22_3069 ENOG4105CNN ABC, transporter BZ22_3071 ENOG4108535 NAD dependent epimerase/dehydratase family BZ22_3073 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BZ22_3076 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BZ22_3079 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BZ22_3080 ENOG4108RS6 transposase BZ22_3081 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BZ22_3082 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ22_3083 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ22_3084 ENOG4105DUU IucA IucC family protein BZ22_3085 ENOG4105CNM Receptor BZ22_3086 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BZ22_3087 ENOG4105DQ5 transport system permease protein BZ22_3088 ENOG4105TVJ transport system, permease BZ22_3089 ENOG4105E0A ABC, transporter BZ22_3090 ENOG4105DUU IucA IucC family protein BZ22_3092 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ22_3093 ENOG4105DY8 decarboxylase BZ22_3094 ENOG4108819 ferric iron reductase BZ22_3095 ENOG4105EE5 Membrane protein terC BZ22_3096 ENOG4108GAE asmA family BZ22_3099 ENOG4105D1F ATP-binding protein BZ22_31 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ22_3104 ENOG4105E5W Transporter BZ22_3106 ENOG41067MG lrgb family BZ22_3109 ENOG4107GZ4 SanA protein BZ22_3110 ENOG4108HWV )-transporter BZ22_3113 ENOG4105DHF Membrane BZ22_3115 ENOG4105CBP Major Facilitator BZ22_3116 ENOG4105EGI Transcriptional regulator BZ22_312 ENOG4108IV0 ABC, transporter BZ22_3121 ENOG4105ENT Efflux transporter rnd family, mfp subunit BZ22_3122 ENOG4105C19 ABC transporter BZ22_3124 ENOG4105CVM Molybdenum cofactor synthesis domain protein BZ22_3125 ENOG4105D06 uba thif-type nad fad binding protein BZ22_3127 ENOG4105C5H ABC transporter BZ22_313 ENOG4105C0Z ABC transporter BZ22_314 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BZ22_3148 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ22_3149 ENOG41062T2 Acyl carrier protein BZ22_315 ENOG4105C32 Amino acid ABC transporter (Permease) BZ22_3151 ENOG4105CHR reductase BZ22_3152 ENOG4108KQ6 Enoyl-CoA hydratase BZ22_3154 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BZ22_3155 ENOG4105CHR reductase BZ22_3156 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ22_3157 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BZ22_316 ENOG4105CP9 extracellular ligand-binding receptor BZ22_3162 ENOG4108BUD transposase BZ22_3164 ENOG4108Z0T Part of a sulfur-relay system (By similarity) BZ22_3168 ENOG4105K4P CoA-binding domain protein BZ22_3169 ENOG4108Q67 UPF0319 protein BZ22_317 ENOG4105U59 -acetyltransferase BZ22_3171 ENOG41088T4 Helicase IV BZ22_3172 ENOG410901E Membrane BZ22_3173 ENOG4105EM2 membrane BZ22_3174 ENOG4108RZ1 DNA transformation protein BZ22_3176 ENOG4105UYK outer membrane protein a BZ22_3177 ENOG4108RS6 transposase BZ22_3179 ENOG4105DAN ATP-dependent protease BZ22_3182 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ22_3183 ENOG4108Q2G (LipO)protein BZ22_3184 ENOG4105DY2 Paraquat-inducible protein b BZ22_3185 ENOG4105F1S paraquat-inducible protein a BZ22_3186 ENOG4105C5H ABC transporter BZ22_3188 ENOG4105QVC MOSC domain-containing protein BZ22_3189 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) BZ22_319 ENOG4105CRP Part of the ABC transporter FtsEX involved in BZ22_3191 ENOG4105CD8 aminopeptidase N BZ22_3195 ENOG4105CGF Aromatic amino acid aminotransferase BZ22_3196 ENOG4105C5X domain protein BZ22_3197 ENOG4105EAQ (twin-arginine translocation) pathway signal BZ22_3198 ENOG4105DIT ErfK YbiS YcfS YnhG family protein BZ22_32 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ22_320 ENOG4105CAK Cell division ATP-binding protein ftsE BZ22_3200 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) BZ22_3201 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) BZ22_3202 ENOG4106371 Methyltransferase BZ22_3203 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups BZ22_3205 ENOG4105W49 UPF0434 protein BZ22_3206 ENOG4105VEQ Cold shock protein BZ22_3207 ENOG4105E32 cytoplasmic protein BZ22_321 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ22_321 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ22_3210 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BZ22_3212 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BZ22_3218 ENOG4105HDK L-asparaginase BZ22_3219 ENOG4105DDY UPF0142 protein ycaO BZ22_322 ENOG4106H78 methyltransferase BZ22_3220 ENOG4105TMB Formate nitrite transporter BZ22_3221 ENOG4105C6N Formate acetyltransferase BZ22_3223 ENOG4105F1A Pyruvate formate-lyase BZ22_3226 ENOG4105D1H recombination factor protein RarA BZ22_3229 ENOG4105CNU cell division protein FtsK BZ22_323 ENOG4105MG3 Membrane BZ22_3230 ENOG4105EW9 transcriptional regulator AsnC family BZ22_3231 ENOG4105C3M thioredoxin reductase BZ22_3232 ENOG4108JJ9 ABC, transporter BZ22_3233 ENOG4108JJ8 (ABC) transporter BZ22_3235 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BZ22_3236 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ22_3238 ENOG4105VEQ Cold shock protein BZ22_3240 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ22_3241 ENOG4108MJ5 VirK protein BZ22_3242 ENOG4105CPB ATP-dependent endonuclease of the OLD family BZ22_3243 ENOG4105DWU Membrane BZ22_3245 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ22_3246 ENOG4105C7K acetolactate synthase BZ22_3247 ENOG4105C5W Aldolase BZ22_3248 ENOG4105CGD Nad-dependent epimerase dehydratase BZ22_3249 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ22_3250 ENOG41064MM (LipO)protein BZ22_3251 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) BZ22_3252 ENOG4105E5Z arginine transporter ATP-binding subunit BZ22_3253 ENOG4106PMH Extracellular solute-binding protein family 3 BZ22_3254 ENOG4105GBT ABC transporter BZ22_3255 ENOG4105DMR ABC, transporter BZ22_3256 ENOG4108I0N Transporter, RarD family, DMT superfamily protein BZ22_3257 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) BZ22_3258 ENOG410642S Nicotianamine synthase protein BZ22_3259 ENOG4105E0A ABC, transporter BZ22_326 ENOG4107FS9 Membrane BZ22_3260 ENOG4108I9K permease protein BZ22_3264 ENOG4106TNF Periplasmic binding protein BZ22_3266 ENOG4105RBQ inner membrane protein ybjO BZ22_3267 ENOG4105D38 putrescine abc transporter BZ22_3268 ENOG4105F38 ABC transporter, permease BZ22_3269 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ22_3270 ENOG4107RUE extracellular solute-binding protein family 1 BZ22_3271 ENOG4108RMJ sensory transduction regulator BZ22_3272 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress BZ22_3273 ENOG41090BQ Glutaredoxin BZ22_3274 ENOG4105D0C transport protein BZ22_3276 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BZ22_3277 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ22_3278 ENOG4107FB0 transcriptional regulator DeoR family BZ22_3279 ENOG4105C44 Serine transporter BZ22_3280 ENOG4105DZ1 carboxypeptidase BZ22_3281 ENOG4108UMI ABC transporter, permease BZ22_3283 ENOG4105D01 (LipO)protein BZ22_3286 ENOG4108TGY Glutathione S-transferase BZ22_3287 ENOG4105D05 Receptor BZ22_3289 ENOG4105EHG Permease protein BZ22_329 ENOG4105EX9 Membrane BZ22_3291 ENOG4108IQI permease BZ22_3293 ENOG4105DUM transcriptional regulator, lysR family BZ22_3294 ENOG4105HMI Membrane BZ22_3296 ENOG4108D1K outer membrane usher protein BZ22_3297 ENOG4108UIF Chaperone BZ22_33 ENOG4105C3U ABC transporter BZ22_330 ENOG4108W1V Lipoprotein BZ22_3300 ENOG4108SGD regulatory protein BZ22_3301 ENOG4105DM4 PTS System BZ22_3302 ENOG4105DE4 1-phosphofructokinase BZ22_3303 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein BZ22_3305 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BZ22_3306 ENOG4105C2J ABC transporter BZ22_3308 ENOG4105E66 phosphoriboisomerase A BZ22_331 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BZ22_3310 ENOG4105C26 Dehydrogenase BZ22_3313 ENOG4105CHR reductase BZ22_3314 ENOG4105KRS Proteinase inhibitor BZ22_3317 ENOG4105CHZ Catalyzes the dehydration of D-mannonate (By similarity) BZ22_3318 ENOG4105DEI Mannitol dehydrogenase BZ22_3319 ENOG4107YCY Transcriptional regulator BZ22_3321 ENOG4105CKI cobalamin synthesis protein BZ22_3322 ENOG41076MN Phosphoesterase, PA-phosphatase related BZ22_3323 ENOG4107TT5 NLP P60 protein BZ22_3324 ENOG4105CXC rtn protein BZ22_3325 ENOG4105E43 Extracellular solute-binding protein, family 5 BZ22_3326 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BZ22_3327 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BZ22_3328 ENOG4108JQ5 ABC transporter BZ22_3329 ENOG4105HG6 BZ22_333 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A BZ22_3330 ENOG4105C2C drug resistance transporter, Bcr CflA BZ22_3331 ENOG4105I08 Pseudouridine synthase BZ22_3332 ENOG4105CFI type iii restriction protein res subunit BZ22_3335 ENOG4105PAN UPF0352 protein BZ22_3336 ENOG4105E68 Sulfatase BZ22_3339 ENOG4105GMB type VI secretion system effector, hcp1 family BZ22_334 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BZ22_3344 ENOG4105CS2 ec 3.2.1.21 BZ22_3346 ENOG4108Q3X Transcriptional regulator BZ22_3350 ENOG4108T86 baseplate J family protein BZ22_3358 ENOG4105TKZ Tail Sheath BZ22_336 ENOG4105DQF Hydrolase BZ22_3362 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BZ22_3363 ENOG4105MVE transcriptional regulator BZ22_3365 ENOG4105G63 Type III effector Hrp-dependent BZ22_3366 ENOG4105HRS Antitermination protein BZ22_3368 ENOG4105Y50 Virulence Protein BZ22_337 ENOG4108EUD Lysophospholipase BZ22_3371 ENOG4105C8Q Methyl-accepting chemotaxis BZ22_3373 ENOG4105CT4 transporter BZ22_3374 ENOG4107R6D beta-lactam binding protein AmpH BZ22_3379 ENOG4105FCK Membrane BZ22_3381 ENOG4106UW1 Major Facilitator superfamily BZ22_3382 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC BZ22_3383 ENOG41068CG regulatoR BZ22_3384 ENOG4105BZU Histidine kinase BZ22_3385 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ22_3387 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ22_3388 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ22_3389 ENOG4105XPH Ferredoxin BZ22_339 ENOG4105CCF Lysine exporter protein (Lyse ygga) BZ22_3392 ENOG4105E0U tyrosine-specific transport protein BZ22_3393 ENOG4108UII YfaZ family BZ22_3394 ENOG4105CH6 catalase BZ22_3395 ENOG4105DVT helicase BZ22_3397 ENOG4105FDR Membrane BZ22_3399 ENOG4105CXN decarboxylase BZ22_34 ENOG4108JQ7 (ABC) transporter BZ22_340 ENOG4105C9U ATP-dependent DNA helicase RecQ BZ22_3400 ENOG4105D5Q Arginine ornithine antiporter BZ22_3401 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component BZ22_3402 ENOG4108IJ8 ABC transporter BZ22_3403 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component BZ22_3404 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BZ22_3405 ENOG4105KHC sulfurtransferase BZ22_3408 ENOG4108IV0 ABC, transporter BZ22_3409 ENOG4108JJB ABC transporter BZ22_341 ENOG4105HDD phospholipase BZ22_3410 ENOG4105CNN ABC, transporter BZ22_3411 ENOG4105C32 Amino acid ABC transporter (Permease) BZ22_3413 ENOG4108W15 Protein of unknown function (DUF1456) BZ22_3416 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein BZ22_3418 ENOG4105Y3U Transglycosylase-associated protein BZ22_342 ENOG4108VUY thioesterase Superfamily protein BZ22_3420 ENOG4105N1F Hnh endonuclease BZ22_3423 ENOG4105CXG d-lactate dehydrogenase BZ22_3424 ENOG41061WM D-Alanyl-D-Alanine BZ22_3426 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BZ22_3428 ENOG4108RS6 transposase BZ22_3429 ENOG4105C1J atp-dependent rna helicase BZ22_343 ENOG4105FR1 rard protein BZ22_3436 ENOG4105C1J atp-dependent rna helicase BZ22_3437 ENOG4107MVR Transcriptional regulator BZ22_3439 ENOG4105CJ1 ABC, transporter BZ22_344 ENOG4107QUT magnesium and cobalt transport protein CorA BZ22_3440 ENOG4107QWP ABC-2 type transporter BZ22_3441 ENOG4107QWP ABC-2 type transporter BZ22_3444 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ22_3446 ENOG4105BZU Histidine kinase BZ22_3448 ENOG4105EAA nucleoside BZ22_3449 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BZ22_3451 ENOG4105CN8 Transcriptional regulator BZ22_3452 ENOG4105C94 Transporter BZ22_3456 ENOG4105HFZ Membrane BZ22_3457 ENOG4108ZAF Molybdopterin BZ22_3458 ENOG4105M00 molybdopterin converting factor, subunit 1 BZ22_346 ENOG4105EQN UPF0261 protein BZ22_3460 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BZ22_3462 ENOG4105CHW UPF0052 protein BZ22_3463 ENOG4105VYA Uncharacterized conserved protein (DUF2132) BZ22_3465 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BZ22_3466 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ22_3467 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BZ22_3472 ENOG4108K4B hydrolase BZ22_3474 ENOG4105E0C molybdate abc transporter BZ22_3475 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BZ22_3476 ENOG410680R Protein of unknown function (DUF2592) BZ22_3477 ENOG4105F4R Transcriptional regulator mode BZ22_3478 ENOG4105DKW ABC transporter BZ22_348 ENOG4105C4R Atp-dependent dna helicase BZ22_3481 ENOG4105CMR udp-glucose 4-epimerase BZ22_3482 ENOG4105F0Z galactose-1-phosphate uridylyltransferase BZ22_3484 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BZ22_3487 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ22_3489 ENOG4105PGM cation diffusion facilitator family transporter BZ22_349 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant BZ22_3490 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BZ22_3498 ENOG4105UFD tol-pal system protein YbgF BZ22_3499 ENOG4105KCK Peptidoglycan-associated lipoprotein BZ22_35 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BZ22_350 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ22_3501 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ22_3501 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ22_3502 ENOG4105M8F Biopolymer transport protein exbD tolR BZ22_3503 ENOG4105E02 MotA TolQ exbB proton channel BZ22_3504 ENOG4107YD3 Thioesterase BZ22_3505 ENOG4105KJB cyd operon protein YbgE BZ22_3507 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BZ22_3508 ENOG4105C4M (Ubiquinol oxidase) subunit I BZ22_3509 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BZ22_351 ENOG4105CT0 Protein of unknown function, DUF484 BZ22_3511 ENOG4105C7S Dehydrogenase BZ22_3512 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BZ22_3513 ENOG4105E33 succinate dehydrogenase BZ22_3515 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BZ22_3516 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BZ22_3517 ENOG4105BZN citrate synthase BZ22_3519 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BZ22_3520 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BZ22_3521 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ22_3523 ENOG4108Z1B Cyclase dehydrase BZ22_3525 ENOG4105DFP Integrase BZ22_3528 ENOG4105EV9 Alpha Beta Hydrolase BZ22_353 ENOG4105S7Z (LipO)protein BZ22_3530 ENOG4105NNH LexA regulated protein BZ22_3531 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) BZ22_3532 ENOG41090R7 Ferric uptake BZ22_3536 ENOG4108RS6 transposase BZ22_3537 ENOG4105CI1 PTS System BZ22_3539 ENOG4105CE4 GlcNAc 6-P deacetylase BZ22_3540 ENOG4105E2R ROK family BZ22_3541 ENOG4105D4U had-superfamily hydrolase, subfamily iia BZ22_3542 ENOG4105CAQ asparagine synthetase BZ22_3549 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ22_355 ENOG4107T0K Adenylate cyclase BZ22_3551 ENOG4105C9A Phoh family BZ22_3553 ENOG4108JU5 Magnesium and cobalt efflux protein BZ22_3554 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BZ22_3555 ENOG4107RP9 extracellular solute-binding protein, family 3 BZ22_3556 ENOG4105EAD ABC transporter BZ22_3557 ENOG4105DRP amino acid AbC transporter BZ22_3558 ENOG4105CDA abc transporter atp-binding protein BZ22_3559 ENOG4107PAI alpha helical protein BZ22_3562 ENOG4105DJF DNA polymerase III, delta' subunit BZ22_3564 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BZ22_3566 ENOG4105CJN penicillin-binding protein BZ22_3567 ENOG4105CNI cell division protein FtsW BZ22_3568 ENOG4105K6T rare lipoprotein A BZ22_3569 ENOG4105DZ1 carboxypeptidase BZ22_357 ENOG41076E6 Uroporphyrinogen-III Synthase BZ22_3573 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) BZ22_3574 ENOG4107Z6W Protein CrcB homolog BZ22_3575 ENOG4105VEQ Cold shock protein BZ22_3577 ENOG4108N8T regulatoR BZ22_358 ENOG4105ECF c-methyltransferase BZ22_3581 ENOG4108JJ7 ABC transporter BZ22_3583 ENOG4105DH8 myo-inositol catabolism BZ22_3585 ENOG4105EDK PfkB domain protein BZ22_3586 ENOG4105CK5 oxidoreductase BZ22_3587 ENOG4105CNN ABC, transporter BZ22_3588 ENOG4105C2J ABC transporter BZ22_3589 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ22_359 ENOG410601J HemY protein BZ22_3591 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BZ22_3592 ENOG4105C26 Dehydrogenase BZ22_3595 ENOG4105DN3 alpha-2-macroglobulin domain protein BZ22_3596 ENOG4108JQB penicillin-binding protein 1C BZ22_3597 ENOG4105HVQ Regulatory factor of maltose metabolism BZ22_36 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BZ22_3602 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ22_3607 ENOG4105EZE Cupin 4 family protein BZ22_3609 ENOG4105FE9 pseudouridine synthase BZ22_3612 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ22_3615 ENOG4107SET aldo keto reductase BZ22_3616 ENOG4105EQ2 LysR family Transcriptional regulator BZ22_3619 ENOG41077RS Phosphatase BZ22_3620 ENOG4105E8V Alpha Beta Hydrolase Fold protein BZ22_3622 ENOG4108HPI phosphatidate Cytidylyltransferase BZ22_3623 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase BZ22_3628 ENOG4105UZW Tail fiber assembly protein BZ22_3645 ENOG4105Y50 Virulence Protein BZ22_3647 ENOG4105UZW Tail fiber assembly protein BZ22_365 ENOG4105C85 amino acid BZ22_3659 ENOG4105TKZ Tail Sheath BZ22_3665 ENOG4108KU3 Integrase BZ22_3669 ENOG4108XS9 dna repair protein BZ22_3670 ENOG4106H6R UPF0380 protein BZ22_3673 ENOG4108MXD gtp-binding protein BZ22_3685 ENOG4105DFP Integrase BZ22_3688 ENOG4105WQ3 Rna-binding protein BZ22_369 ENOG4105EGZ biosynthesis protein BZ22_3690 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ22_3692 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BZ22_3693 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BZ22_3694 ENOG4105CV6 ABC transporter, permease BZ22_3695 ENOG4108I0Y (ABC) transporter BZ22_3696 ENOG4108UJV acyl-CoA thioesterase i BZ22_3697 ENOG4105E1F short-chain dehydrogenase reductase BZ22_3698 ENOG4107QR8 Thioredoxin BZ22_3699 ENOG4107QX8 SPFH domain, Band 7 family protein BZ22_37 ENOG4107RJJ Transcriptional regulator BZ22_370 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ22_3700 ENOG4105G5H Membrane BZ22_3701 ENOG4108Z6Z Transcriptional regulator BZ22_3702 ENOG4105C59 p-type ATPase BZ22_3703 ENOG4105MBR gumn family BZ22_3704 ENOG4108Z66 YbaK ebsC protein BZ22_3707 ENOG4105CGH 5'-nucleotidase BZ22_3708 ENOG4105CGH 5'-nucleotidase BZ22_3709 ENOG4105EU0 Major facilitator Superfamily BZ22_371 ENOG4108WJ1 acetyltransferase BZ22_3710 ENOG4108RS6 transposase BZ22_3711 ENOG4105EU0 Major facilitator Superfamily BZ22_3712 ENOG4105CKD glutathione-regulated potassium-efflux system protein BZ22_3713 ENOG4107RE1 Inosine-guanosine kinase BZ22_3714 ENOG4108QY5 Ferric enterobactin transport protein BZ22_3716 ENOG4105DMT epimerase dehydratase BZ22_3718 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BZ22_3719 ENOG4105C30 Nad-dependent epimerase dehydratase BZ22_372 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BZ22_3720 ENOG4105C0K Gdp-mannose 4,6-dehydratase BZ22_3721 ENOG4108TJN glycosyl transferase group 1 BZ22_3723 ENOG41081E6 Inherit from COG: Polysaccharide biosynthesis protein BZ22_3725 ENOG4108SMP Nad-dependent epimerase dehydratase BZ22_3726 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ22_3727 ENOG4105FAW cDP-glucose 4,6-dehydratase BZ22_3728 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BZ22_3729 ENOG4108EX3 reductase BZ22_373 ENOG4105C1B dTDP-glucose 4-6-dehydratase BZ22_3735 ENOG4107QMP dna polymerase iii subunits gamma and tau BZ22_3737 ENOG4105WD1 Membrane BZ22_3739 ENOG4105EGS Mechanosensitive ion channel BZ22_374 ENOG4108IJ1 Dehydrogenase BZ22_3740 ENOG41090EX DsrE family BZ22_3741 ENOG4108IG5 Transcriptional regulator BZ22_3742 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ22_3743 ENOG4105BZS acriflavin resistance protein BZ22_3744 ENOG4108RS6 transposase BZ22_3746 ENOG4105YK5 50S ribosomal protein L36 BZ22_3748 ENOG4108UKR Biofilm formation regulator YbaJ BZ22_3749 ENOG4105KF5 hemolysin expression-modulating protein BZ22_375 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BZ22_3750 ENOG41080UX Methyltransferase BZ22_3751 ENOG4108MNP Glycoprotein polysaccharide metabolism BZ22_3752 ENOG4105C29 acyl-CoA thioesterase BZ22_3753 ENOG4105BZU Histidine kinase BZ22_3754 ENOG4108YZA Nitrogen regulatory protein pii BZ22_3755 ENOG4105BZ1 (ABC) transporter BZ22_3756 ENOG4105BZ1 (ABC) transporter BZ22_3757 ENOG4108XM1 transcriptional regulator AsnC family BZ22_3758 ENOG4105C6T cysteine synthase BZ22_376 ENOG4105SFE lipopolysaccharide biosynthesis protein BZ22_3760 ENOG4108NFA extracellular solute-binding protein BZ22_3762 ENOG4108TGP Thioesterase superfamily protein BZ22_3763 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BZ22_3764 ENOG4105EIN peptidylprolyl cis-trans isomerase BZ22_3765 ENOG4105K70 DNA-binding protein BZ22_3766 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BZ22_377 ENOG4105ESV Glycosyl transferase, family 4 BZ22_3771 ENOG4105M85 Bola protein BZ22_3772 ENOG4105IEY (LipO)protein BZ22_3773 ENOG4105EYM Major Facilitator superfamily BZ22_3775 ENOG4105E2S oxidase) subunit II BZ22_3776 ENOG4105BZ9 Cytochrome C oxidase, subunit I BZ22_3777 ENOG4105CCU oxidase (Subunit III) BZ22_3778 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BZ22_3780 ENOG4107RDB Major Facilitator BZ22_3782 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BZ22_3783 ENOG4107S0N DJ-1 family BZ22_3786 ENOG4105CTB Polyprenyl synthetase BZ22_3788 ENOG4108ZAI phosphatidylglycerophosphatase a BZ22_3789 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BZ22_379 ENOG4105K63 Thioredoxin BZ22_3792 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BZ22_3795 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ22_3796 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ22_3797 ENOG4105VIE preprotein translocase, subunit YajC BZ22_38 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG BZ22_3801 ENOG4105D3R alkyl hydroperoxide reductase BZ22_3803 ENOG4107FW0 short-chain dehydrogenase reductase BZ22_3804 ENOG4107R28 alpha amylase, catalytic region BZ22_3805 ENOG4105C85 amino acid BZ22_3806 ENOG4105CWM branched-chain amino acid transport system II carrier protein BZ22_3808 ENOG4105BZU Histidine kinase BZ22_3809 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BZ22_3810 ENOG4107RH8 nuclease SbcCD subunit D BZ22_3811 ENOG4105EYH Exonuclease BZ22_3812 ENOG4105DKQ ROK family BZ22_3817 ENOG4105F2W methyltransferase BZ22_382 ENOG4105C4R Atp-dependent dna helicase BZ22_3828 ENOG4105CIN aminoacyl-histidine dipeptidase BZ22_383 ENOG4105KQ5 peptidylprolyl cis-trans isomerase BZ22_3832 ENOG4105CJ2 (LipO)protein BZ22_3836 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ22_3837 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ22_3838 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ22_3839 ENOG4105E7A Glutamine amidotransferase BZ22_3840 ENOG4105F7V ErfK ybiS ycfS ynhG family protein BZ22_3842 ENOG4107QPN acyl-Coa dehydrogenase BZ22_3844 ENOG4106YJS accessory processing protein BZ22_3848 ENOG4108RS6 transposase BZ22_3854 ENOG4105CHM Aminotransferase BZ22_3857 ENOG4105C5R Aminotransferase BZ22_3859 ENOG4105E5Q amino acid AbC transporter BZ22_386 ENOG4105GQR Chaperone BZ22_3861 ENOG4105F87 Dehydratase BZ22_3866 ENOG4105EQ0 Major Facilitator superfamily BZ22_3867 ENOG4108UMN azlc family BZ22_3868 ENOG4105ZED uncharacterized protein ygaH BZ22_3869 ENOG4105NTK Transcriptional repressor Mpra BZ22_387 ENOG4105CW0 outer membrane usher protein BZ22_3870 ENOG4105CW7 secretion protein, HlyD family BZ22_3871 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ22_3872 ENOG4105EIB trna rrna methyltransferase BZ22_3873 ENOG4105K63 Thioredoxin BZ22_3874 ENOG4106IUH DTW domain containing protein BZ22_3875 ENOG4105CD5 CoA-binding domain protein BZ22_3876 ENOG4105JIM Phosphatidylserine synthase BZ22_3877 ENOG4105T42 (LipO)protein BZ22_3884 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ22_3885 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ22_3886 ENOG4105C34 Pseudouridine synthase BZ22_3887 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BZ22_3888 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA BZ22_389 ENOG4108VEV chaperone BZ22_3891 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ22_3892 ENOG4108NEV two component transcriptional regulator, LytTR family BZ22_3893 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ22_3894 ENOG4108NE3 Salt-induced outer membrane protein BZ22_3899 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BZ22_39 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH BZ22_3900 ENOG4106KVJ cytochrome C assembly protein BZ22_3901 ENOG4108JU6 CBS domain protein BZ22_3904 ENOG4105W39 Membrane BZ22_3905 ENOG4107VXZ Hydrolase BZ22_3911 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BZ22_3919 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BZ22_3920 ENOG4108IUS Transketolase BZ22_3921 ENOG4108HHA Transketolase BZ22_3922 ENOG4105CNN ABC, transporter BZ22_3923 ENOG4105C2J ABC transporter BZ22_3927 ENOG4108XVM Cytochrome b(562) BZ22_3928 ENOG4105CPW cytochrome b561 BZ22_3929 ENOG4108NEM leader-binding protein dmsD BZ22_3930 ENOG4107KGK dmso reductase anchor subunit BZ22_3931 ENOG4105QAX Iron-sulfur BZ22_3932 ENOG4107QY8 reductase BZ22_3933 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ22_3934 ENOG4105E98 transcriptional regulator DeoR family BZ22_3936 ENOG4105C2J ABC transporter BZ22_3937 ENOG4105CNN ABC, transporter BZ22_3938 ENOG4105F5R ABC transporter BZ22_3939 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase BZ22_3940 ENOG4105CMG Carbohydrate kinase BZ22_3941 ENOG4107GFK fumarate BZ22_3943 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ22_3945 ENOG4105D05 Receptor BZ22_3947 ENOG4105CA0 peroxidase BZ22_3948 ENOG4105E89 ABC transporter BZ22_395 ENOG4105EMY transcriptional regulator BZ22_3953 ENOG4105DKT Transcriptional regulator BZ22_3955 ENOG4105CMT Dihydroxyacetone kinase BZ22_3956 ENOG4105CHR reductase BZ22_3957 ENOG4105CPQ Dehydrogenase BZ22_3958 ENOG4108YZG isomerase BZ22_3960 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ22_3961 ENOG4108K5P (LipO)protein BZ22_3968 ENOG4105N0Z inner membrane protein ygbE BZ22_3969 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BZ22_3978 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BZ22_3979 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BZ22_3983 ENOG4105DXN mazG family BZ22_3984 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ22_3985 ENOG4105BZU Histidine kinase BZ22_3986 ENOG4105C0H protease BZ22_399 ENOG4105C7B Threonine dehydratase BZ22_3990 ENOG4105EN6 Membrane BZ22_3994 ENOG4105S6R Iron-hydroxamate transporter permease subunit BZ22_3995 ENOG4105J76 Periplasmic binding protein BZ22_3996 ENOG4105E0A ABC, transporter BZ22_3997 ENOG4105BZ4 penicillin-binding protein BZ22_3998 ENOG4105CQ7 ATP-dependent helicase BZ22_3999 ENOG4107XID 2'-5' rna ligase BZ22_4 ENOG4108XCZ PTS System BZ22_40 ENOG4105EKV Phosphonate metabolism protein BZ22_4001 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BZ22_4003 ENOG4105DJ0 Poly(A) Polymerase BZ22_4004 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BZ22_4008 ENOG4107BJW polysaccharide deacetylase BZ22_4009 ENOG4105E3A (ABC) transporter BZ22_401 ENOG4105CM2 brancheD-chain amino acid aminotransferase BZ22_4010 ENOG4105DA5 (ABC) transporter BZ22_4011 ENOG41077A9 carbonic anhydrase BZ22_4012 ENOG4108UGV hypoxanthine phosphoribosyltransferase BZ22_4013 ENOG4105E3B Multicopper oxidase BZ22_4014 ENOG4108ZRK uncharacterized protein yacC BZ22_4017 ENOG4105RPH Inner membrane protein YddG BZ22_4019 ENOG4107QIJ Aconitate hydratase 2 BZ22_402 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit BZ22_4020 ENOG4108RS6 transposase BZ22_4021 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ22_4022 ENOG4107QSN dihydrolipoamide acetyltransferase BZ22_4023 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BZ22_4024 ENOG41073TP transcriptional regulator BZ22_4025 ENOG4105C85 amino acid BZ22_4026 ENOG4106A72 regulatory protein AmpE BZ22_4027 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ22_4028 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BZ22_4029 ENOG4108ZUW Major pilin subunit BZ22_4030 ENOG4107QHF type ii secretion system protein e BZ22_4031 ENOG4105D7Q type ii secretion system BZ22_4033 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BZ22_4036 ENOG4108RS6 transposase BZ22_4037 ENOG4105M6F mutator MutT protein BZ22_404 ENOG4105C0P Mg chelatase subunit ChlI BZ22_4042 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BZ22_4043 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BZ22_4044 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BZ22_4048 ENOG4105CNI cell division protein FtsW BZ22_405 ENOG4108WFC UPF0438 protein yifE BZ22_4051 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BZ22_4052 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BZ22_4053 ENOG4105CJN penicillin-binding protein BZ22_4054 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BZ22_4057 ENOG4108RNS Exports L-alanine (By similarity) BZ22_4058 ENOG4107B7Y DNA-binding transcriptional regulator FruR BZ22_4059 ENOG4108ZP8 Acetolactate synthase small subunit BZ22_406 ENOG41062B0 ABC transporter, permease BZ22_4060 ENOG4105C7K acetolactate synthase BZ22_4061 ENOG4108IQE Amp-dependent synthetase and ligase BZ22_4062 ENOG41064T2 transcriptional regulator, lysR family BZ22_4065 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BZ22_4068 ENOG4105S8Q sugar efflux transporter BZ22_4071 ENOG4105DP9 ABC transporter BZ22_4072 ENOG4106SMU thiamine transporter membrane protein BZ22_4074 ENOG4108KF1 Membrane BZ22_4075 ENOG4105CQ2 DNA polymerase BZ22_408 ENOG4107R9N ABC transporter BZ22_4086 ENOG4105CS6 Rhs element vgr protein BZ22_4087 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ22_409 ENOG4105C2J ABC transporter BZ22_4096 ENOG4105D3G Pseudouridine synthase BZ22_4097 ENOG41066UG Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity) BZ22_4099 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BZ22_41 ENOG4105FT8 Phosphonate metabolism BZ22_410 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator BZ22_4105 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BZ22_4107 ENOG4105DWK Membrane BZ22_4108 ENOG4108NIW Leucine export protein LeuE BZ22_4109 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BZ22_4110 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BZ22_4113 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BZ22_4116 ENOG4105DTN riboflavin biosynthesis protein ribF BZ22_4118 ENOG41063Z6 transcriptional regulator, lysR family BZ22_4122 ENOG4106HK8 GPR1 FUN34 yaaH family protein BZ22_4125 ENOG4108RIR Molybdenum cofactor biosynthesis protein BZ22_4133 ENOG41065U4 response regulator BZ22_4134 ENOG4108RH0 Crea protein BZ22_4137 ENOG4105UEI Transcriptional Regulator AraC Family BZ22_4138 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) BZ22_4140 ENOG4107SC1 transglycosylase BZ22_4143 ENOG4108KHX Diguanylate cyclase BZ22_4144 ENOG41090EK ompa motb domain protein BZ22_4145 ENOG4105C5H ABC transporter BZ22_4147 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase BZ22_4148 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BZ22_4149 ENOG4105EAC phosphoserine phosphatase BZ22_4150 ENOG41062Z9 Membrane BZ22_4154 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ22_4155 ENOG4105D9N nucleoside BZ22_4156 ENOG4105EYA deoxyribonuclease BZ22_4157 ENOG4108NRW Phospholipase, patatin family BZ22_4159 ENOG4105K3G Periplasmic Protein BZ22_4161 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BZ22_4162 ENOG4108WPU DNA polymerase III subunit psi BZ22_4167 ENOG4105YBH Protein of unknown function (DUF1435) BZ22_4168 ENOG4105BZU Histidine kinase BZ22_4171 ENOG4105BZS acriflavin resistance protein BZ22_4172 ENOG410624X efflux transporter, rnd family, mfp subunit BZ22_4175 ENOG4105DKP glycosyl transferase, family 9 BZ22_4177 ENOG4105DKT Transcriptional regulator BZ22_4184 ENOG4105RI1 glycoprotein receptor BZ22_4185 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BZ22_42 ENOG4105ENV phosphonate C-P lyase system protein PhnK BZ22_420 ENOG4108Y73 Membrane BZ22_422 ENOG4105C5Q Transcriptional regulator BZ22_424 ENOG4105EHV domain protein BZ22_425 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ22_426 ENOG4105YHG TonB family BZ22_427 ENOG4107QZV Type I secretion membrane fusion protein BZ22_43 ENOG4105HRV phosphonate c-p lyase system protein phnl BZ22_430 ENOG4105X58 receptor BZ22_436 ENOG4105SYT Methylenetetrahydrofolate reductase BZ22_437 ENOG4105CFH Aspartokinase BZ22_438 ENOG4105C28 cystathionine BZ22_439 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) BZ22_44 ENOG4105FD8 phosphonate metabolism protein PhnM BZ22_440 ENOG4108Z12 YiaAB two helix domain-containing protein BZ22_442 ENOG4105C25 Primosomal protein n' BZ22_444 ENOG4105ETE Transcriptional regulator (LacI family BZ22_445 ENOG41063M6 Cell Division Protein BZ22_448 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BZ22_45 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) BZ22_452 ENOG4108MBX Secretion Protein BZ22_453 ENOG4108JJA ABC, transporter BZ22_455 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BZ22_456 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BZ22_457 ENOG4105CBT Fructose-1,6-bisphosphatase BZ22_458 ENOG4105DP0 ferredoxin-NADP reductase BZ22_459 ENOG4108VTS Membrane BZ22_46 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein BZ22_460 ENOG4105EBK exported protein BZ22_462 ENOG4107F9Y LysR family transcriptional regulator BZ22_464 ENOG4105JSC dimethylmenaquinone methyltransferase BZ22_465 ENOG4107QPK )-transporter BZ22_467 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BZ22_47 ENOG4105K4T epimerase BZ22_472 ENOG4105FMW periplasmic BZ22_473 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ22_474 ENOG4105E0F Histidine kinase BZ22_475 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ22_476 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BZ22_477 ENOG4105D7W serine acetyltransferase BZ22_480 ENOG4105VW4 glutaredoxin 3 BZ22_481 ENOG4107YZP Rhodanese domain protein BZ22_483 ENOG41063SB peptidase BZ22_484 ENOG4105PXI polysaccharide deacetylase BZ22_486 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BZ22_488 ENOG4105XA0 heptosyltransferase ii BZ22_489 ENOG4105D16 lipopolysaccharide heptosyltransferase i BZ22_490 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BZ22_494 ENOG4105W0E 50S ribosomal protein L33 BZ22_497 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BZ22_502 ENOG4105DSJ YicC domain protein BZ22_51 ENOG4105DRS transport system, permease BZ22_514 ENOG4105EN6 Membrane BZ22_515 ENOG410649J Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction (By similarity) BZ22_517 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BZ22_518 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ22_519 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase BZ22_52 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BZ22_520 ENOG4105CB5 ATP-dependent DNA helicase recG BZ22_521 ENOG4105D6U Sodium Glutamate Symporter BZ22_522 ENOG4105C2W permease BZ22_523 ENOG4105JV1 AsmA family BZ22_524 ENOG4105SUU thioesterase domain BZ22_527 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 BZ22_529 ENOG4105C5F glutamine synthetase BZ22_530 ENOG4105CUX Signal transduction histidine kinase BZ22_531 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ22_532 ENOG4105D4P Coproporphyrinogen iii oxidase BZ22_535 ENOG4105C2M dna polymerase I BZ22_536 ENOG4108Z33 Thiol disulfide Interchange Protein BZ22_537 ENOG4105E27 serine threonine protein kinase BZ22_538 ENOG4105PC1 Conserved Protein BZ22_540 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b BZ22_546 ENOG4107EJG GntR family transcriptional regulator BZ22_548 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ22_549 ENOG4108RVA ribokinase BZ22_555 ENOG4108VVK transcriptional Regulator, AsnC BZ22_556 ENOG4105QTB Flavodoxin BZ22_559 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation BZ22_561 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BZ22_569 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BZ22_57 ENOG4108YYD acetyltransferase BZ22_571 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BZ22_572 ENOG4105C8U phosphate abc transporter BZ22_573 ENOG4105E2Z phosphate ABC transporter (Permease BZ22_577 ENOG4106PMH Extracellular solute-binding protein family 3 BZ22_578 ENOG4105EAD ABC transporter BZ22_579 ENOG4105DRP amino acid AbC transporter BZ22_58 ENOG4105XPQ lipid carrier protein BZ22_580 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 BZ22_581 ENOG4105C7N Xanthine uracil vitamin C permease BZ22_586 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BZ22_589 ENOG4105VG0 50S ribosomal protein l34 BZ22_59 ENOG4105CFP Peptidase U32 BZ22_592 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BZ22_593 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BZ22_594 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ22_595 ENOG410667J hydrolase BZ22_597 ENOG4105C7B Threonine dehydratase BZ22_598 ENOG4105D99 atp gtp-binding protein BZ22_599 ENOG4105R2A (LipO)protein BZ22_6 ENOG4108M3P Membrane BZ22_60 ENOG4106RZ4 Peptidase U32 BZ22_603 ENOG4105JKW Valine--pyruvate aminotransferase BZ22_605 ENOG4107T9C Alpha amylase catalytic region BZ22_608 ENOG4108ZG0 Ompa motb domain protein BZ22_61 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BZ22_610 ENOG4108R3E Dna-3-methyladenine glycosylase i BZ22_613 ENOG4106JH6 (LipO)protein BZ22_614 ENOG4105CTS PTS system mannitol-specific BZ22_616 ENOG4105E61 Mannitol repressor protein BZ22_618 ENOG4108YYI Protein of unknown function (DUF2810) BZ22_62 ENOG4105BZS acriflavin resistance protein BZ22_622 ENOG4105C8Q Methyl-accepting chemotaxis BZ22_623 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ22_625 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ22_626 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ22_627 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BZ22_628 ENOG4108MG3 formate dehydrogenase BZ22_631 ENOG4105EM7 Selenocysteine-specific translation elongation factor BZ22_637 ENOG4105MEV Acyl-transferase BZ22_638 ENOG4106EAR Fimbrial protein BZ22_640 ENOG4108TTM chaperone BZ22_642 ENOG4105CMG Carbohydrate kinase BZ22_644 ENOG4105DFW ABC transporter BZ22_646 ENOG4107RNG ABC transporter BZ22_647 ENOG4105T16 Transcriptional regulator (AraC family) BZ22_649 ENOG4105DFP Integrase BZ22_65 ENOG4105DEN Luciferase family BZ22_656 ENOG4105CMM transposase BZ22_657 ENOG4108IPW abc transporter atp-binding protein BZ22_658 ENOG4105CM4 permease protein BZ22_664 ENOG4105C6T cysteine synthase BZ22_667 ENOG4105C85 amino acid BZ22_669 ENOG4105DIJ Phosphoethanolamine transferase BZ22_670 ENOG4108KX4 response regulator BZ22_671 ENOG4105BZU Histidine kinase BZ22_672 ENOG4105CXY transporter BZ22_676 ENOG4105D5K Hemolysin activator protein BZ22_678 ENOG4105DEF Extracellular solute-binding protein, family 5 BZ22_679 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ22_68 ENOG4105C1J atp-dependent rna helicase BZ22_680 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ22_681 ENOG4105C3U ABC transporter BZ22_682 ENOG4108JQ7 (ABC) transporter BZ22_683 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BZ22_684 ENOG4105BZU Histidine kinase BZ22_685 ENOG4108PU9 oligogalacturonate-specific porin BZ22_690 ENOG4105CS0 peptidase BZ22_691 ENOG4107SS6 2-dehydro-3-deoxygluconokinase BZ22_692 ENOG4105VSH 4-oxalocrotonate tautomerase BZ22_693 ENOG4105CMB EAL domain-containing protein BZ22_694 ENOG41066T0 asmA family BZ22_695 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) BZ22_696 ENOG4107H3J ribonuclease BZ22_701 ENOG4105BZW Glycerate kinase BZ22_702 ENOG4107QQ0 gntp family BZ22_703 ENOG4107VHA regulatoR BZ22_704 ENOG4105DC8 reductase BZ22_705 ENOG4105D6S protein involved in catabolism of external DNA BZ22_706 ENOG4105DGW oligopeptidase A BZ22_710 ENOG4108M6U Universal stress protein A BZ22_712 ENOG4105CJ3 phosphate transporter BZ22_713 ENOG4105CBX hi0933 family BZ22_716 ENOG4105CNN ABC, transporter BZ22_717 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ22_719 ENOG4105D2N Aldolase BZ22_721 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ22_723 ENOG4105C2I pirin domain protein BZ22_724 ENOG4105DIQ Transcriptional regulator BZ22_725 ENOG4105C6Z Gluconate BZ22_726 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ22_730 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BZ22_731 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ22_736 ENOG4108HRK Histidine kinase BZ22_741 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ22_742 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BZ22_746 ENOG4105E98 transcriptional regulator DeoR family BZ22_75 ENOG4105CHV Transcription elongation factor NusA BZ22_750 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ22_751 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) BZ22_753 ENOG4105MJ2 Competence protein BZ22_755 ENOG4105RID UPF0379 protein yhcN BZ22_758 ENOG4105XFK Ferrous iron transport protein A BZ22_759 ENOG4105BZM domain protein BZ22_760 ENOG4108RRZ Transcription elongation factor GreB BZ22_761 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ22_762 ENOG4105E0F Histidine kinase BZ22_765 ENOG4105VEJ Heat shock protein BZ22_766 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 BZ22_767 ENOG4105DQY intracellular growth attenuator BZ22_769 ENOG4107RK2 ADP-ribose diphosphatase NudE BZ22_771 ENOG4105UZW Tail fiber assembly protein BZ22_786 ENOG4105NVB glycoside hydrolase, family 19 BZ22_789 ENOG4105ZIA Phage protein gp16 BZ22_804 ENOG4105HVQ Regulatory factor of maltose metabolism BZ22_806 ENOG4108JQC penicillin-binding protein 1A BZ22_81 ENOG4105EEI dihydropteroate synthase BZ22_811 ENOG4105E4G Type IV pilus BZ22_816 ENOG4105DJV ribulose-phosphate 3-epimerase BZ22_817 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BZ22_818 ENOG4105C31 Tryptophanyl-tRNA synthetase BZ22_82 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BZ22_820 ENOG4107V9H nitrite transporter BZ22_821 ENOG4105WZK nitrite reductase NADPH small subunit BZ22_822 ENOG4107QZF nitrite reductase NADPH large subunit BZ22_823 ENOG4105DZC cytosine deaminase BZ22_826 ENOG41060NJ transcriptional regulator BZ22_827 ENOG4105F8D glycoside hydrolase family 4 BZ22_828 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ22_829 ENOG4105D7A ATP-binding protein BZ22_831 ENOG4105C8Y Acetylornithine aminotransferase BZ22_832 ENOG410613R integral membrane protein, YccS YhfK family BZ22_834 ENOG4108UKZ OsmC family BZ22_836 ENOG4105GMB type VI secretion system effector, hcp1 family BZ22_839 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) BZ22_84 ENOG4105HBR Rna-binding protein BZ22_841 ENOG4105DNZ Alpha Beta Hydrolase BZ22_843 ENOG4106FTQ Taurine ABC transporter, periplasmic BZ22_845 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ22_846 ENOG4105E2B Taurine dioxygenase BZ22_848 ENOG4105K64 Glycosyl transferase, family 2 BZ22_849 ENOG4105C5H ABC transporter BZ22_85 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BZ22_852 ENOG4105VKU nucleicacid-binding protein BZ22_853 ENOG4108YZY peptidylprolyl cis-trans isomerase BZ22_855 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ22_856 ENOG4105WWK YheO domain protein BZ22_86 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase BZ22_861 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BZ22_864 ENOG4108RS6 transposase BZ22_873 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BZ22_875 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BZ22_876 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BZ22_878 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BZ22_887 ENOG4105VPB 50S ribosomal protein L30 BZ22_889 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BZ22_890 ENOG41067V7 50S ribosomal protein L36 BZ22_893 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BZ22_896 ENOG4105W1Y Transcriptional regulator BZ22_897 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system BZ22_899 ENOG4105C1A potassium transporter peripheral membrane BZ22_9 ENOG4105DZR Type I site-specific deoxyribonuclease BZ22_903 ENOG4105C79 DNA protecting protein DprA BZ22_905 ENOG4108WI1 Dna topoisomerase BZ22_908 ENOG4108Z0R Transferase BZ22_916 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BZ22_924 ENOG4105PM1 preprotein translocase subunit SecE BZ22_925 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BZ22_933 ENOG4105D41 biosynthesis protein thiH BZ22_936 ENOG4105D06 uba thif-type nad fad binding protein BZ22_938 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BZ22_943 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BZ22_944 ENOG4105R2J Conserved Protein BZ22_946 ENOG4108T8B Protein of unknown function (DUF1481) BZ22_947 ENOG4105C12 Phosphoribosylglycinamide synthetase BZ22_959 ENOG4107QP3 malate synthase g BZ22_960 ENOG4108I9X Isocitrate lyase BZ22_962 ENOG41069M3 Transcriptional regulator BZ22_963 ENOG4105C3R Methionine synthase BZ22_967 ENOG4105CFH Aspartokinase BZ22_970 ENOG4105EG2 ABC transporter, permease BZ22_971 ENOG4105D56 permease protein BZ22_972 ENOG4107FKK extracellular solute-binding protein family 1 BZ22_975 ENOG4107W52 maltose operon periplasmic protein BZ22_977 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ22_987 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ22_993 ENOG4105CS6 Rhs element vgr protein BZ22_995 ENOG4105CNA YD repeat protein