locus-tag	class	description
BZ22_1	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ22_1001	COG3209	COG3209 Rhs family protein
BZ22_1003	COG3501	Rhs element vgr protein
BZ22_1005	COG0673	inositol 2-dehydrogenase activity
BZ22_1006	COG2207	Transcriptional regulator
BZ22_1007	COG1869	D-ribose catabolic process
BZ22_1008	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_101	COG0697	spore germination
BZ22_1010	COG0431	NADPH-dependent FMN reductase
BZ22_1011	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZ22_1013	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ22_1015	COG3077	Addiction module antitoxin, RelB DinJ family
BZ22_1016	COG2252	PERMEase
BZ22_1017	COG3328	transposase activity
BZ22_1018	COG0025	NhaP-type Na H and K H
BZ22_1020	COG1560	Kdo2-lipid A biosynthetic process
BZ22_1022	COG1129	ABC transporter
BZ22_1023	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_1025	COG1069	ribulokinase activity
BZ22_1027	COG0625	glutathione transferase activity
BZ22_1031	COG1278	Cold shock
BZ22_1032	COG1278	Cold shock
BZ22_1033	COG1278	Cold shock
BZ22_1034	COG3133	Outer membrane lipoprotein
BZ22_1035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZ22_1037	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ22_104	COG0142	geranyltranstransferase activity
BZ22_1041	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BZ22_1042	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ22_1044	COG4145	pantothenate transmembrane transporter activity
BZ22_1045	COG3924	membrane
BZ22_1047	COG0439	Biotin carboxylase
BZ22_1048	COG0511	ligase activity, forming carbon-carbon bonds
BZ22_1052	COG0604	alcohol dehydrogenase
BZ22_1053	COG2199	diguanylate cyclase activity
BZ22_1053	COG2200	EAL domain
BZ22_1054	COG1077	Cell shape determining protein MreB Mrl
BZ22_1055	COG1792	Involved in formation and maintenance of cell shape
BZ22_1056	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BZ22_1058	COG1530	ribonuclease E activity
BZ22_1059	COG3164	Protein of unknown function
BZ22_106	COG3423	Transcriptional regulator
BZ22_1060	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ22_1061	COG0312	modulator of DNA gyrase
BZ22_1070	COG0583	DNA-binding transcription factor activity
BZ22_1076	COG2732	(Barnase) inhibitor
BZ22_1078	COG0312	modulator of DNA gyrase
BZ22_1080	COG3783	Cytochrome b(562)
BZ22_1081	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ22_1082	COG0366	Alpha amylase catalytic
BZ22_1083	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_1083	COG1263	PTS System
BZ22_1084	COG1609	Transcriptional regulator
BZ22_1089	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_1091	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_1093	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BZ22_1094	COG1137	ATPase activity
BZ22_1095	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BZ22_1096	COG3117	lipopolysaccharide transmembrane transporter activity
BZ22_1097	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BZ22_1098	COG0517	IMP dehydrogenase activity
BZ22_1098	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BZ22_1099	COG0530	calcium, potassium:sodium antiporter activity
BZ22_11	COG0582	viral genome integration into host DNA
BZ22_110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BZ22_1100	COG1127	ABC transporter
BZ22_1101	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BZ22_1102	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BZ22_1103	COG2854	intermembrane phospholipid transfer
BZ22_1104	COG3113	response to antibiotic
BZ22_1105	COG5007	Belongs to the BolA IbaG family
BZ22_1107	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ22_1108	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ22_1109	COG3105	Protein conserved in bacteria
BZ22_1111	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BZ22_1114	COG0625	glutathione transferase activity
BZ22_1115	COG2969	positive regulation of protein catabolic process
BZ22_1117	COG0493	'glutamate synthase
BZ22_1118	COG0070	glutamate synthase
BZ22_1118	COG0067	glutamate synthase
BZ22_1118	COG0069	glutamate synthase activity
BZ22_112	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BZ22_1120	COG1242	4 iron, 4 sulfur cluster binding
BZ22_1122	COG0784	Response regulator, receiver
BZ22_1122	COG2198	Histidine kinase
BZ22_1122	COG5002	protein histidine kinase activity
BZ22_1123	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BZ22_1125	COG2823	Periplasmic or secreted lipoprotein
BZ22_1129	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BZ22_113	COG2105	PFAM AIG2 family protein
BZ22_1130	COG1741	Belongs to the pirin family
BZ22_1131	COG0583	DNA-binding transcription factor activity
BZ22_1132	COG0435	Glutathione S-transferase
BZ22_1133	COG2259	Doxx family
BZ22_1135	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
BZ22_1136	COG4575	ribosome binding
BZ22_1139	COG0586	Pfam SNARE associated Golgi protein
BZ22_114	COG2911	Protein conserved in bacteria
BZ22_1142	COG2271	Major facilitator Superfamily
BZ22_1144	COG0246	Mannitol dehydrogenase
BZ22_1145	COG2721	sulfolactate sulfo-lyase activity
BZ22_1148	COG0673	inositol 2-dehydrogenase activity
BZ22_1149	COG1451	nucleotide metabolic process
BZ22_115	COG0729	surface antigen
BZ22_1152	COG0446	pyridine nucleotide-disulphide oxidoreductase
BZ22_1152	COG1902	pentaerythritol trinitrate reductase activity
BZ22_1153	COG3247	response to pH
BZ22_1156	COG4245	von Willebrand factor, type A
BZ22_1159	COG4245	von Willebrand factor, type A
BZ22_1160	COG2831	hemolysin activation secretion protein
BZ22_1161	COG3210	domain, Protein
BZ22_1166	COG3210	domain, Protein
BZ22_1168	COG3210	domain, Protein
BZ22_117	COG1253	flavin adenine dinucleotide binding
BZ22_1170	COG3210	domain, Protein
BZ22_1174	COG3842	ATPase activity
BZ22_1175	COG3459	Glycosyltransferase 36 associated
BZ22_1176	COG1609	Transcriptional regulator
BZ22_1177	COG1653	transport
BZ22_1179	COG0395	ABC-type sugar transport system, permease component
BZ22_1183	COG1289	transmembrane transporter activity
BZ22_119	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BZ22_1191	COG0251	oxidation-reduction process
BZ22_1198	COG3157	Type VI secretion system effector, Hcp
BZ22_1204	COG3561	AntA/AntB antirepressor
BZ22_121	COG0737	Belongs to the 5'-nucleotidase family
BZ22_1221	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZ22_1222	COG0358	DNA primase activity
BZ22_1226	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BZ22_1229	COG4991	sh3 domain protein
BZ22_123	COG0545	Peptidyl-prolyl cis-trans isomerase
BZ22_1230	COG3025	triphosphatase activity
BZ22_1233	COG0531	amino acid
BZ22_1236	COG3384	dioxygenase
BZ22_1237	COG0754	glutathionylspermidine amidase activity
BZ22_124	COG3061	Opacity-associated protein A
BZ22_1240	COG1538	Outer membrane efflux protein
BZ22_1241	COG0494	nUDIX hydrolase
BZ22_1242	COG3151	Protein conserved in bacteria
BZ22_1243	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
BZ22_1244	COG3150	esterase
BZ22_1245	COG0187	DNA topoisomerase II activity
BZ22_1246	COG0583	DNA-binding transcription factor activity
BZ22_1247	COG2249	NAD(P)H dehydrogenase (quinone) activity
BZ22_1248	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BZ22_1249	COG0204	Acyl-transferase
BZ22_1250	COG2132	Multicopper oxidase
BZ22_1252	COG0656	L-ascorbic acid biosynthetic process
BZ22_1253	COG1979	alcohol dehydrogenase
BZ22_1254	COG2207	Transcriptional regulator
BZ22_1255	COG0586	Pfam SNARE associated Golgi protein
BZ22_1256	COG0626	cystathionine gamma-synthase activity
BZ22_1257	COG0811	peptide transport
BZ22_1259	COG0848	biopolymer transport protein
BZ22_127	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BZ22_1270	COG4964	Belongs to the GSP D family
BZ22_1277	COG3397	chitin binding
BZ22_1278	COG3469	chitinase activity
BZ22_128	COG0360	Binds together with S18 to 16S ribosomal RNA
BZ22_1283	COG4592	Periplasmic binding protein
BZ22_1287	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ22_1288	COG1684	flagellar biosynthetic protein fliR
BZ22_1289	COG1987	bacterial-type flagellum assembly
BZ22_1293	COG2204	response regulator
BZ22_130	COG1073	alpha beta
BZ22_1302	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BZ22_1303	COG1815	bacterial-type flagellum-dependent cell motility
BZ22_1304	COG1558	bacterial-type flagellum-dependent cell motility
BZ22_1305	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BZ22_1306	COG1749	Flagellar hook protein flgE
BZ22_1309	COG3710	Transcriptional regulator
BZ22_131	COG3650	response to hydrogen peroxide
BZ22_1313	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BZ22_1318	COG3133	Outer membrane lipoprotein
BZ22_1319	COG3300	MHYT domain
BZ22_1319	COG5001	Diguanylate cyclase
BZ22_132	COG1960	acyl-CoA dehydrogenase activity
BZ22_1320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ22_1322	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ22_1329	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BZ22_133	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ22_1330	COG2195	Cleaves the N-terminal amino acid of tripeptides
BZ22_1331	COG4771	TonB-dependent receptor
BZ22_1332	COG3433	isochorismatase activity
BZ22_1332	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ22_1332	COG2226	methyltransferase
BZ22_1333	COG2226	methyltransferase
BZ22_1333	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BZ22_1333	COG3433	isochorismatase activity
BZ22_1339	COG1132	(ABC) transporter
BZ22_134	COG0557	exoribonuclease II activity
BZ22_1343	COG2610	gluconate transmembrane transporter activity
BZ22_1345	COG3501	Rhs element vgr protein
BZ22_1347	COG3209	COG3209 Rhs family protein
BZ22_1349	COG3209	COG3209 Rhs family protein
BZ22_1351	COG3209	COG3209 Rhs family protein
BZ22_1353	COG3209	COG3209 Rhs family protein
BZ22_1359	COG0471	metal ion transport
BZ22_1360	COG1609	Transcriptional regulator
BZ22_1362	COG2211	Major facilitator Superfamily
BZ22_137	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BZ22_1371	COG3916	Acyl-homoserine-lactone synthase
BZ22_1372	COG2771	luxR family
BZ22_138	COG0330	HflC and HflK could
BZ22_139	COG0330	HflC and HflK could
BZ22_1392	COG1982	Orn Lys Arg decarboxylase major
BZ22_1393	COG1879	ABC-type sugar transport system periplasmic component
BZ22_1394	COG1129	ABC transporter
BZ22_1395	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_1396	COG4774	siderophore transport
BZ22_140	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BZ22_1400	COG1194	a g-specific adenine glycosylase
BZ22_1402	COG3171	Protein conserved in bacteria
BZ22_1403	COG2066	Belongs to the glutaminase family
BZ22_1405	COG1073	alpha beta
BZ22_1405	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BZ22_1405	COG3064	Membrane
BZ22_1406	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZ22_1407	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BZ22_1409	COG0762	integral membrane protein
BZ22_1410	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BZ22_1411	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BZ22_1412	COG2805	Type II/IV secretion system protein
BZ22_1414	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ22_1417	COG0189	ligase activity
BZ22_1418	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BZ22_1419	COG2356	endonuclease I
BZ22_1423	COG1166	arginine decarboxylase activity
BZ22_1424	COG1943	Transposase
BZ22_1426	COG1943	Transposase
BZ22_1427	COG0501	Belongs to the peptidase M48B family
BZ22_1428	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BZ22_1431	COG0191	fructose-bisphosphate aldolase activity
BZ22_1436	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BZ22_1437	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BZ22_1438	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BZ22_144	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZ22_1441	COG0006	proline dipeptidase activity
BZ22_1442	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ22_1443	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ22_1448	COG5295	Hep Hag repeat protein
BZ22_145	COG0802	atpase or kinase
BZ22_1450	COG1272	protein, Hemolysin III
BZ22_1453	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BZ22_1454	COG0745	RESPONSE REGULATOR receiver
BZ22_1455	COG2205	protein histidine kinase activity
BZ22_1456	COG4452	Inner membrane protein CreD
BZ22_1457	COG0716	FMN binding
BZ22_146	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BZ22_146	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BZ22_147	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BZ22_1472	COG4695	Portal protein
BZ22_1490	COG5301	cellulose 1,4-beta-cellobiosidase activity
BZ22_1496	COG4974	Belongs to the 'phage' integrase family
BZ22_1497	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZ22_1498	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BZ22_1502	COG0582	viral genome integration into host DNA
BZ22_1537	COG1695	Transcriptional regulator
BZ22_1538	COG0791	NLP P60 protein
BZ22_1540	COG1879	ABC-type sugar transport system periplasmic component
BZ22_1541	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_1542	COG1129	ABC transporter
BZ22_1544	COG2182	Extracellular solute-binding protein
BZ22_1545	COG1175	transmembrane transport
BZ22_1546	COG3833	ABC-type maltose transport systems, permease component
BZ22_1547	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BZ22_1548	COG1874	Beta-galactosidase
BZ22_1549	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_1549	COG1263	PTS System
BZ22_155	COG3264	Mechanosensitive ion channel
BZ22_155	COG1511	domain protein
BZ22_1553	COG2271	Major facilitator Superfamily
BZ22_1557	COG0191	fructose-bisphosphate aldolase activity
BZ22_1559	COG3119	arylsulfatase activity
BZ22_1560	COG0641	radical SAM
BZ22_1562	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_1564	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_1565	COG3716	PTS system mannose fructose sorbose family IID component
BZ22_1566	COG3715	PTS system
BZ22_1567	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_1568	COG2222	sugar isomerase
BZ22_157	COG1053	succinate dehydrogenase
BZ22_1570	COG1349	DNA-binding transcription factor activity
BZ22_1571	COG3119	arylsulfatase activity
BZ22_1576	COG0288	reversible hydration of carbon dioxide
BZ22_158	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BZ22_1594	COG0840	transmembrane signaling receptor activity
BZ22_1597	COG0583	DNA-binding transcription factor activity
BZ22_1598	COG2814	Major facilitator Superfamily
BZ22_1599	COG1609	Transcriptional regulator
BZ22_160	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BZ22_1600	COG0019	diaminopimelate decarboxylase activity
BZ22_1606	COG0667	Aldo Keto reductase
BZ22_161	COG2076	Multidrug Resistance protein
BZ22_1616	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BZ22_1618	COG1074	ATP-dependent DNA helicase activity
BZ22_1619	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BZ22_1621	COG0860	N-Acetylmuramoyl-L-alanine amidase
BZ22_1625	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BZ22_1626	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BZ22_1627	COG2166	iron-sulfur cluster assembly
BZ22_1628	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BZ22_1630	COG0583	DNA-binding transcription factor activity
BZ22_1631	COG2363	Small membrane protein
BZ22_1634	COG1611	Belongs to the LOG family
BZ22_1637	COG3098	single-species biofilm formation
BZ22_1638	COG0564	pseudouridine synthase activity
BZ22_1643	COG0024	Methionine aminopeptidase
BZ22_1649	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BZ22_1650	COG0575	Belongs to the CDS family
BZ22_1651	COG0750	zinc metalloprotease
BZ22_1653	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BZ22_1657	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BZ22_1659	COG0587	DNA-directed DNA polymerase activity
BZ22_1661	COG0346	lactoylglutathione lyase activity
BZ22_1664	COG4568	rho-dependent transcription termination
BZ22_1666	COG4681	YaeQ
BZ22_1668	COG3015	lipoprotein NlpE involved in copper resistance
BZ22_1670	COG1720	tRNA m6t6A37 methyltransferase activity
BZ22_1672	COG1464	Belongs to the NlpA lipoprotein family
BZ22_1673	COG2011	ABC-type metal ion transport system permease component
BZ22_1675	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BZ22_1681	COG0656	L-ascorbic acid biosynthetic process
BZ22_1684	COG0741	lytic transglycosylase activity
BZ22_1684	COG1388	LysM domain
BZ22_1686	COG2226	methyltransferase
BZ22_1688	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BZ22_169	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZ22_1690	COG1953	Uracil, thiamine, allantoin
BZ22_1692	COG2113	Glycine betaine
BZ22_1693	COG4176	ABC-type proline glycine betaine transport system permease component
BZ22_1694	COG4175	Glycine betaine
BZ22_1695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZ22_1703	COG1278	Cold shock
BZ22_1704	COG0747	negative chemotaxis
BZ22_1706	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ22_1707	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BZ22_1708	COG1124	(ABC) transporter
BZ22_1715	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BZ22_1717	COG4413	Urea transporter
BZ22_1718	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
BZ22_172	COG3383	formate dehydrogenase (NAD+) activity
BZ22_1720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BZ22_1721	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BZ22_1723	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZ22_1724	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BZ22_1725	COG1447	Phosphotransferase system cellobiose-specific component IIA
BZ22_1726	COG1917	Cupin 2, conserved barrel domain protein
BZ22_1726	COG2169	Transcriptional regulator
BZ22_173	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ22_1730	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BZ22_1731	COG0033	Phosphoglucomutase
BZ22_1734	COG0745	RESPONSE REGULATOR receiver
BZ22_1735	COG2205	protein histidine kinase activity
BZ22_174	COG0493	'glutamate synthase
BZ22_174	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ22_1740	COG3272	Protein of unknown function (DUF1722)
BZ22_1742	COG5212	phosphodiesterase
BZ22_1743	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BZ22_1745	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BZ22_1746	COG1984	allophanate hydrolase subunit 2
BZ22_175	COG1309	transcriptional regulator
BZ22_1757	COG0513	Belongs to the DEAD box helicase family
BZ22_1759	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BZ22_1761	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BZ22_1762	COG3026	antisigma factor binding
BZ22_1763	COG3086	response to oxidative stress
BZ22_1766	COG0681	Belongs to the peptidase S26 family
BZ22_1770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BZ22_1772	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ22_18	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BZ22_1826	COG1737	Transcriptional regulator
BZ22_1828	COG0560	Phosphoserine phosphatase
BZ22_1829	COG0590	tRNA wobble adenosine to inosine editing
BZ22_1834	COG2205	protein histidine kinase activity
BZ22_1835	COG3170	Tfp pilus assembly protein FimV
BZ22_1836	COG2204	response regulator
BZ22_1837	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BZ22_1837	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZ22_1838	COG0347	Belongs to the P(II) protein family
BZ22_1839	COG2188	Transcriptional regulator
BZ22_1840	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ22_1840	COG1017	nitric oxide dioxygenase activity
BZ22_1843	COG3711	transcriptional antiterminator
BZ22_1844	COG2814	Major facilitator Superfamily
BZ22_1845	COG3683	transport system, periplasmic component
BZ22_1846	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BZ22_1847	COG0483	inositol monophosphate 1-phosphatase activity
BZ22_1850	COG1104	cysteine desulfurase activity
BZ22_1851	COG0822	iron-sulfur transferase activity
BZ22_1855	COG0633	Ferredoxin
BZ22_1856	COG2975	iron-sulfur cluster assembly
BZ22_1859	COG3468	outer membrane autotransporter barrel domain protein
BZ22_1868	COG2976	Protein conserved in bacteria
BZ22_1869	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ22_1872	COG1645	bacterial-type flagellum-dependent swarming motility
BZ22_1874	COG0516	GMP reductase activity
BZ22_1874	COG0517	IMP dehydrogenase activity
BZ22_188	COG1454	alcohol dehydrogenase
BZ22_1889	COG0351	phosphomethylpyrimidine kinase
BZ22_1894	COG3422	double-strand break repair
BZ22_1895	COG0745	RESPONSE REGULATOR receiver
BZ22_1896	COG2205	protein histidine kinase activity
BZ22_19	COG0582	viral genome integration into host DNA
BZ22_190	COG0629	single-stranded DNA binding
BZ22_1901	COG3842	ATPase activity
BZ22_1903	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BZ22_1905	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ22_1906	COG1177	transmembrane transport
BZ22_1908	COG0443	Heat shock 70 kDa protein
BZ22_1909	COG2239	Acts as a magnesium transporter
BZ22_191	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BZ22_1910	COG0248	Ppx GppA phosphatase
BZ22_1911	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BZ22_1913	COG0581	inorganic phosphate transmembrane transporter activity
BZ22_1916	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ22_1917	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BZ22_192	COG2315	Protein conserved in bacteria
BZ22_1920	COG2233	PERMEase
BZ22_1922	COG1393	Belongs to the ArsC family
BZ22_1923	COG4783	chaperone-mediated protein folding
BZ22_1924	COG0628	permease
BZ22_1927	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BZ22_1928	COG2716	regulation of RNA biosynthetic process
BZ22_193	COG1448	Aminotransferase
BZ22_1930	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BZ22_1932	COG2321	neutral zinc metallopeptidase
BZ22_1936	COG1876	peptidase activity
BZ22_1938	COG1393	Belongs to the ArsC family
BZ22_194	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BZ22_1940	COG1840	ABC-type Fe3 transport system, periplasmic component
BZ22_1941	COG1175	transmembrane transport
BZ22_1942	COG3842	ATPase activity
BZ22_1943	COG3119	arylsulfatase activity
BZ22_1944	COG0641	radical SAM
BZ22_1945	COG1988	membrane-bound metal-dependent
BZ22_1947	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ22_1949	COG2197	response regulator
BZ22_195	COG0305	Participates in initiation and elongation during chromosome replication
BZ22_1950	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ22_1950	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BZ22_1951	COG3062	negative regulation of establishment of protein localization
BZ22_1953	COG3043	anaerobic respiration
BZ22_1954	COG3005	denitrification pathway
BZ22_1962	COG3111	PFAM Bacterial OB fold (BOF) protein
BZ22_1964	COG2837	iron assimilation
BZ22_1965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BZ22_1967	COG4886	Leucine-rich repeat (LRR) protein
BZ22_1969	COG2731	YhcH YjgK YiaL family protein
BZ22_1970	COG1737	Transcriptional regulator
BZ22_1972	COG4150	thiosulfate binding
BZ22_1973	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BZ22_1974	COG4208	sulfate ABC transporter
BZ22_1976	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BZ22_1978	COG0745	RESPONSE REGULATOR receiver
BZ22_1979	COG5002	protein histidine kinase activity
BZ22_1979	COG3850	Histidine kinase
BZ22_198	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ22_1981	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BZ22_1982	COG0006	proline dipeptidase activity
BZ22_1984	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BZ22_1987	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ22_1988	COG0745	RESPONSE REGULATOR receiver
BZ22_1989	COG2205	protein histidine kinase activity
BZ22_199	COG0735	belongs to the Fur family
BZ22_1990	COG2190	(PTS) system
BZ22_1992	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_1993	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BZ22_1994	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
BZ22_1997	COG3530	Putative quorum-sensing-regulated virulence factor
BZ22_2	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ22_2008	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZ22_201	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BZ22_2011	COG0667	Aldo Keto reductase
BZ22_2016	COG0436	Aminotransferase
BZ22_2017	COG3038	cytochrome b561
BZ22_2023	COG3381	protein complex oligomerization
BZ22_2024	COG3302	dmso reductase anchor subunit
BZ22_2025	COG0437	4 iron, 4 sulfur cluster binding
BZ22_2026	COG0243	molybdopterin cofactor binding
BZ22_2034	COG2951	lytic endotransglycosylase activity
BZ22_2046	COG3121	Chaperone
BZ22_2047	COG3188	usher protein
BZ22_2056	COG3501	Rhs element vgr protein
BZ22_2062	COG2824	Alkylphosphonate utilization operon protein PhnA
BZ22_2064	COG1704	LemA family
BZ22_2068	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ22_2069	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ22_2070	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BZ22_2072	COG1138	Cytochrome C-type biogenesis protein
BZ22_2073	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZ22_2074	COG3088	subunit of a heme lyase
BZ22_2074	COG4235	cytochrome complex assembly
BZ22_2075	COG4235	cytochrome complex assembly
BZ22_2075	COG3088	subunit of a heme lyase
BZ22_2078	COG3691	Protein conserved in bacteria
BZ22_208	COG3121	Chaperone
BZ22_2081	COG2062	phosphohistidine phosphatase, SixA
BZ22_2083	COG2890	protein-(glutamine-N5) methyltransferase activity
BZ22_2086	COG0730	response to heat
BZ22_2087	COG3101	peptidyl-lysine hydroxylation
BZ22_2090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ22_2091	COG1794	racemase activity, acting on amino acids and derivatives
BZ22_2094	COG0697	spore germination
BZ22_2097	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZ22_2099	COG0586	Pfam SNARE associated Golgi protein
BZ22_21	COG0795	lipopolysaccharide-transporting ATPase activity
BZ22_2101	COG0285	dihydrofolate synthase activity
BZ22_2102	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BZ22_2103	COG1286	toxin biosynthetic process
BZ22_2104	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BZ22_2105	COG0163	prenyltransferase activity
BZ22_2106	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_2107	COG4215	(ABC) transporter
BZ22_2108	COG4160	amino acid transport
BZ22_2109	COG4598	ABC transporter
BZ22_2110	COG1090	epimerase
BZ22_2112	COG0622	Phosphoesterase
BZ22_2113	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BZ22_2114	COG3037	sugar-specific permease SgaT UlaA
BZ22_2117	COG1609	Transcriptional regulator
BZ22_2118	COG0280	phosphate acetyltransferase
BZ22_2118	COG0857	belongs to the CobB CobQ family
BZ22_2122	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ22_2123	COG0490	domain, Protein
BZ22_2123	COG0471	metal ion transport
BZ22_2126	COG0436	Aminotransferase
BZ22_2127	COG0583	DNA-binding transcription factor activity
BZ22_2129	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ22_2131	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BZ22_2133	COG1034	ATP synthesis coupled electron transport
BZ22_2136	COG0839	Belongs to the complex I subunit 6 family
BZ22_2138	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BZ22_2139	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ22_2142	COG2731	YhcH YjgK YiaL family protein
BZ22_2143	COG3265	gluconokinase activity
BZ22_2144	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_2146	COG1609	Transcriptional regulator
BZ22_2147	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ22_2150	COG0129	dihydroxy-acid dehydratase activity
BZ22_2152	COG4575	ribosome binding
BZ22_2154	COG1169	isochorismate synthase
BZ22_2157	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BZ22_2160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BZ22_2164	COG1126	abc transporter atp-binding protein
BZ22_2165	COG0765	amino acid transport
BZ22_2166	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_2172	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BZ22_2176	COG1063	alcohol dehydrogenase
BZ22_2177	COG1879	ABC-type sugar transport system periplasmic component
BZ22_2178	COG1129	ABC transporter
BZ22_2179	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_2180	COG1609	Transcriptional regulator
BZ22_2181	COG0583	DNA-binding transcription factor activity
BZ22_2182	COG0473	3-isopropylmalate dehydrogenase activity
BZ22_2183	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ22_2184	COG4638	Rieske (2fe-2S)
BZ22_2185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ22_2186	COG2831	hemolysin activation secretion protein
BZ22_2187	COG3210	domain, Protein
BZ22_2189	COG2963	transposase activity
BZ22_2190	COG3210	domain, Protein
BZ22_2193	COG1476	TRANSCRIPTIONal
BZ22_2194	COG3210	domain, Protein
BZ22_2196	COG3842	ATPase activity
BZ22_2198	COG1609	Transcriptional regulator
BZ22_22	COG0795	lipopolysaccharide-transporting ATPase activity
BZ22_220	COG1358	cellular component organization or biogenesis
BZ22_2201	COG0395	ABC-type sugar transport system, permease component
BZ22_2202	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BZ22_2206	COG0668	transmembrane transport
BZ22_2209	COG1518	maintenance of DNA repeat elements
BZ22_2210	COG1203	CRISPR-associated helicase, Cas3
BZ22_2215	COG0667	Aldo Keto reductase
BZ22_2217	COG0477	Major facilitator Superfamily
BZ22_2219	COG0583	DNA-binding transcription factor activity
BZ22_2220	COG3916	Acyl-homoserine-lactone synthase
BZ22_2221	COG2771	luxR family
BZ22_2226	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BZ22_2227	COG2943	transferase activity, transferring hexosyl groups
BZ22_2228	COG5645	(Lipo)protein
BZ22_2229	COG3104	oligopeptide transport
BZ22_2230	COG1560	Kdo2-lipid A biosynthetic process
BZ22_2233	COG0628	permease
BZ22_2239	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BZ22_2240	COG1530	ribonuclease E activity
BZ22_2241	COG0564	pseudouridine synthase activity
BZ22_2242	COG1943	Transposase
BZ22_2244	COG1399	metal-binding, possibly nucleic acid-binding protein
BZ22_2245	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BZ22_2249	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_225	COG3721	Heme iron utilization protein
BZ22_2251	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ22_2252	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZ22_2253	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BZ22_2255	COG0470	DNA polymerase III
BZ22_2256	COG0084	hydrolase, TatD family'
BZ22_2257	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_2257	COG1263	PTS System
BZ22_2258	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BZ22_2259	COG0537	adenosine 5'-monophosphoramidase activity
BZ22_226	COG0702	epimerase
BZ22_2260	COG5633	Lipoprotein
BZ22_2265	COG1252	NADH dehydrogenase
BZ22_2268	COG3134	Outer membrane lipoprotein
BZ22_2269	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BZ22_2270	COG4591	ABC-type transport system involved in lipoprotein release permease component
BZ22_2272	COG4591	ABC-type transport system involved in lipoprotein release permease component
BZ22_2274	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BZ22_2276	COG2850	peptidyl-arginine hydroxylation
BZ22_2278	COG0745	RESPONSE REGULATOR receiver
BZ22_228	COG4771	TonB-dependent receptor
BZ22_2280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BZ22_2284	COG1187	pseudouridine synthase activity
BZ22_2285	COG0538	isocitrate dehydrogenase activity
BZ22_2288	COG0840	transmembrane signaling receptor activity
BZ22_2289	COG0702	epimerase
BZ22_229	COG3720	iron ion transport
BZ22_2290	COG1733	regulation of RNA biosynthetic process
BZ22_2295	COG1522	sequence-specific DNA binding
BZ22_2298	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_2298	COG3321	synthase
BZ22_2298	COG0604	alcohol dehydrogenase
BZ22_230	COG4558	Periplasmic binding protein
BZ22_2300	COG1278	Cold shock
BZ22_2302	COG0840	transmembrane signaling receptor activity
BZ22_2303	COG1285	pathogenesis
BZ22_2308	COG1360	Flagellar Motor Protein
BZ22_2309	COG2198	Histidine kinase
BZ22_2309	COG0643	Histidine kinase
BZ22_231	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_2310	COG0835	chemotaxis
BZ22_2313	COG0840	transmembrane signaling receptor activity
BZ22_2316	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BZ22_2318	COG0745	RESPONSE REGULATOR receiver
BZ22_2319	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BZ22_2320	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ22_2321	COG5295	Hep Hag repeat protein
BZ22_2321	COG5295	Hep Hag repeat protein
BZ22_2321	COG5295	Hep Hag repeat protein
BZ22_2324	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BZ22_233	COG0626	cystathionine gamma-synthase activity
BZ22_2334	COG3121	Chaperone
BZ22_2338	COG3008	intermembrane lipid transfer
BZ22_2339	COG2995	paraquat-inducible protein a
BZ22_234	COG0814	amino acid
BZ22_2340	COG1956	GAF domain-containing protein
BZ22_2342	COG0793	Belongs to the peptidase S41A family
BZ22_2345	COG3539	Fimbrial protein
BZ22_2346	COG3121	Chaperone
BZ22_2349	COG3121	Chaperone
BZ22_235	COG0583	DNA-binding transcription factor activity
BZ22_2350	COG2814	Major facilitator Superfamily
BZ22_2351	COG0823	Involved in the tonB-independent uptake of proteins
BZ22_2353	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ22_2355	COG1988	membrane-bound metal-dependent
BZ22_2356	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZ22_2357	COG1653	transport
BZ22_2358	COG3842	ATPase activity
BZ22_2359	COG0395	ABC-type sugar transport system, permease component
BZ22_236	COG0425	Belongs to the sulfur carrier protein TusA family
BZ22_2360	COG1175	transmembrane transport
BZ22_2362	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_2364	COG1917	Cupin 2, conserved barrel domain protein
BZ22_2365	COG3328	transposase activity
BZ22_2367	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ22_237	COG2391	methyltransferase activity
BZ22_2370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ22_2371	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ22_2372	COG1121	(ABC) transporter
BZ22_2373	COG0803	Belongs to the bacterial solute-binding protein 9 family
BZ22_2377	COG4249	Peptidase C14 caspase catalytic subunit p20
BZ22_2384	COG0776	regulation of translation
BZ22_2387	COG0386	Belongs to the glutathione peroxidase family
BZ22_2388	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BZ22_2396	COG0791	NLP P60 protein
BZ22_24	COG2927	DNA polymerase III (CHI subunit)
BZ22_2401	COG0574	Belongs to the PEP-utilizing enzyme family
BZ22_2401	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZ22_2402	COG0628	permease
BZ22_2403	COG0277	FAD linked oxidase domain protein
BZ22_2403	COG0247	lactate metabolic process
BZ22_2404	COG2050	protein possibly involved in aromatic compounds catabolism
BZ22_2405	COG0316	Belongs to the HesB IscA family
BZ22_2406	COG0719	Fe-S assembly protein
BZ22_2407	COG0396	ATPase activity
BZ22_2408	COG0719	Fe-S assembly protein
BZ22_2411	COG1376	ErfK ybiS ycfS ynhG family protein
BZ22_2411	COG1388	LysM domain
BZ22_2412	COG4238	major outer membrane lipoprotein
BZ22_2418	COG0307	riboflavin synthase, alpha
BZ22_2419	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BZ22_2420	COG2814	Major facilitator Superfamily
BZ22_2422	COG0583	DNA-binding transcription factor activity
BZ22_2425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZ22_2426	COG0791	NLP P60 protein
BZ22_2428	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BZ22_2430	COG0346	lactoylglutathione lyase activity
BZ22_2432	COG1902	pentaerythritol trinitrate reductase activity
BZ22_2433	COG1309	transcriptional regulator
BZ22_2434	COG2194	sulfuric ester hydrolase activity
BZ22_2435	COG3313	Fe-S protein
BZ22_2436	COG4989	oxidoreductase activity
BZ22_2438	COG3133	Outer membrane lipoprotein
BZ22_2440	COG3895	Periplasmic Protein
BZ22_2444	COG0625	glutathione transferase activity
BZ22_2447	COG3104	oligopeptide transport
BZ22_2448	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ22_2448	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BZ22_2449	COG4172	Belongs to the ABC transporter superfamily
BZ22_2451	COG4171	peptide transport system, permease
BZ22_2452	COG4168	peptide transport system, permease
BZ22_2453	COG4166	transmembrane transport
BZ22_2454	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BZ22_2455	COG1842	Phage shock protein A
BZ22_2457	COG1983	PspC domain protein
BZ22_2459	COG3106	COG3106 Predicted ATPase
BZ22_2464	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BZ22_2465	COG4948	Mandelate Racemase Muconate Lactonizing
BZ22_2466	COG2866	Carboxypeptidase
BZ22_2467	COG4166	transmembrane transport
BZ22_2470	COG2755	lipolytic protein G-D-S-L family
BZ22_2470	COG0657	acetylesterase activity
BZ22_2473	COG0674	pyruvate-flavodoxin oxidoreductase activity
BZ22_2473	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BZ22_2473	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BZ22_2473	COG1013	pyruvate-flavodoxin oxidoreductase activity
BZ22_2475	COG1285	pathogenesis
BZ22_2476	COG3042	response to heat
BZ22_2477	COG3187	Heat shock protein
BZ22_2478	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZ22_2479	COG2911	Protein conserved in bacteria
BZ22_2481	COG3784	Protein of unknown function (DUF1318)
BZ22_2482	COG0246	Mannitol dehydrogenase
BZ22_2483	COG2390	Transcriptional regulator
BZ22_2485	COG1643	Atp-dependent helicase
BZ22_2488	COG3591	Belongs to the peptidase S1B family
BZ22_2490	COG3038	cytochrome b561
BZ22_2494	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BZ22_2495	COG2205	protein histidine kinase activity
BZ22_2496	COG0745	RESPONSE REGULATOR receiver
BZ22_2498	COG0531	amino acid
BZ22_2500	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BZ22_2501	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BZ22_2502	COG0589	response to stress
BZ22_2503	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZ22_2504	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZ22_2507	COG1011	Hydrolase
BZ22_2508	COG0440	acetolactate synthase activity
BZ22_2509	COG0028	Belongs to the TPP enzyme family
BZ22_2514	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BZ22_2515	COG1116	anion transmembrane transporter activity
BZ22_2516	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ22_2517	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZ22_2519	COG1129	ABC transporter
BZ22_2520	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_2521	COG1879	ABC-type sugar transport system periplasmic component
BZ22_2523	COG1609	Transcriptional regulator
BZ22_2524	COG1757	Na H antiporter
BZ22_2525	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BZ22_2531	COG1012	belongs to the aldehyde dehydrogenase family
BZ22_2532	COG3284	Transcriptional regulator
BZ22_2533	COG4221	oxidoreductase activity
BZ22_2537	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BZ22_2539	COG1940	carbohydrate kinase activity
BZ22_2540	COG0583	DNA-binding transcription factor activity
BZ22_2541	COG2814	Major facilitator Superfamily
BZ22_2543	COG0114	fumarate hydratase activity
BZ22_2544	COG1482	cell wall glycoprotein biosynthetic process
BZ22_2545	COG5339	Protein conserved in bacteria
BZ22_2547	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_2547	COG1263	PTS System
BZ22_2547	COG2190	(PTS) system
BZ22_2552	COG0385	Bile acid
BZ22_2553	COG0673	inositol 2-dehydrogenase activity
BZ22_2555	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_2557	COG1879	ABC-type sugar transport system periplasmic component
BZ22_2561	COG2274	protein secretion by the type I secretion system
BZ22_2563	COG2274	protein secretion by the type I secretion system
BZ22_2568	COG2207	Transcriptional regulator
BZ22_2568	COG3708	Transcriptional regulator
BZ22_2570	COG4659	FMN binding
BZ22_2572	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BZ22_2573	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_2574	COG2271	Major facilitator Superfamily
BZ22_2576	COG1966	Carbon starvation protein
BZ22_2577	COG2879	small protein
BZ22_2578	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZ22_2582	COG0023	Translation Initiation Factor
BZ22_2585	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BZ22_2586	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BZ22_2587	COG0671	phosphoesterase, PA-phosphatase related
BZ22_2588	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZ22_2589	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BZ22_259	COG1301	dicarboxylic acid transport
BZ22_2591	COG0583	DNA-binding transcription factor activity
BZ22_2592	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BZ22_2595	COG0616	signal peptide processing
BZ22_2596	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_2598	COG1187	pseudouridine synthase activity
BZ22_2599	COG0009	L-threonylcarbamoyladenylate synthase
BZ22_2602	COG0512	Glutamine amidotransferase of anthranilate synthase
BZ22_2604	COG0135	phosphoribosylanthranilate isomerase activity
BZ22_2604	COG0134	indole-3-glycerol-phosphate synthase activity
BZ22_2608	COG3047	cAMP biosynthetic process
BZ22_261	COG3162	membrane
BZ22_2612	COG1607	acyl-coa hydrolase
BZ22_2613	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BZ22_2615	COG2350	Protein conserved in bacteria
BZ22_2622	COG4608	Belongs to the ABC transporter superfamily
BZ22_2623	COG0444	Belongs to the ABC transporter superfamily
BZ22_2624	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ22_2625	COG0601	transmembrane transport
BZ22_2627	COG2095	MarC family integral membrane protein
BZ22_2628	COG1012	belongs to the aldehyde dehydrogenase family
BZ22_2628	COG1454	alcohol dehydrogenase
BZ22_2629	COG1435	thymidine kinase activity
BZ22_2632	COG0745	RESPONSE REGULATOR receiver
BZ22_2634	COG0788	formyltetrahydrofolate deformylase activity
BZ22_2637	COG0583	DNA-binding transcription factor activity
BZ22_2638	COG0708	Exodeoxyribonuclease III
BZ22_2639	COG0494	nUDIX hydrolase
BZ22_264	COG2801	Transposase and inactivated derivatives
BZ22_2641	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BZ22_2643	COG0778	Nitroreductase
BZ22_2644	COG0616	signal peptide processing
BZ22_2645	COG0252	asparaginase activity
BZ22_2646	COG1335	isochorismatase
BZ22_2647	COG3139	Protein of unknown function (DUF1315)
BZ22_2651	COG3713	MltA-interacting MipA family protein
BZ22_2652	COG2766	serine protein kinase
BZ22_2655	COG0583	DNA-binding transcription factor activity
BZ22_2657	COG2814	Major facilitator Superfamily
BZ22_2659	COG2719	SpoVR family
BZ22_2665	COG1104	cysteine desulfurase activity
BZ22_2668	COG0179	Fumarylacetoacetate (FAA) hydrolase
BZ22_2669	COG2951	lytic endotransglycosylase activity
BZ22_2672	COG2894	cell division
BZ22_2673	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BZ22_2674	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BZ22_2675	COG0318	PFAM AMP-dependent synthetase and ligase
BZ22_2676	COG3065	identical protein binding
BZ22_2678	COG1199	ATP-dependent helicase activity
BZ22_2679	COG0251	oxidation-reduction process
BZ22_2682	COG0800	Aldolase
BZ22_2684	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BZ22_2685	COG1737	Transcriptional regulator
BZ22_2686	COG0469	pyruvate kinase activity
BZ22_2687	COG1560	Kdo2-lipid A biosynthetic process
BZ22_2688	COG0739	heme binding
BZ22_2689	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BZ22_2691	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BZ22_2696	COG0494	nUDIX hydrolase
BZ22_2698	COG1801	Protein of unknown function DUF72
BZ22_2699	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BZ22_27	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BZ22_2703	COG3102	Protein conserved in bacteria
BZ22_2707	COG0728	peptidoglycan biosynthetic process
BZ22_271	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BZ22_2710	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ22_2713	COG3381	protein complex oligomerization
BZ22_2716	COG1940	carbohydrate kinase activity
BZ22_2717	COG0584	glycerophosphoryl diester phosphodiesterase
BZ22_2719	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ22_272	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BZ22_2720	COG3833	ABC-type maltose transport systems, permease component
BZ22_2725	COG0659	secondary active sulfate transmembrane transporter activity
BZ22_2727	COG2912	Transglutaminase-like superfamily
BZ22_2728	COG3094	Invasion gene expression up-regulator, SirB
BZ22_2729	COG2890	protein-(glutamine-N5) methyltransferase activity
BZ22_273	COG1739	Uncharacterized protein family UPF0029
BZ22_2734	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZ22_2737	COG0012	GTP binding
BZ22_2743	COG5002	protein histidine kinase activity
BZ22_2752	COG0500	methyltransferase
BZ22_2765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_2766	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BZ22_2769	COG0402	S-adenosylhomocysteine deaminase activity
BZ22_2781	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZ22_2782	COG3850	Histidine kinase
BZ22_2783	COG0387	Pfam Sodium calcium exchanger
BZ22_2784	COG1943	Transposase
BZ22_2785	COG1702	phosphate starvation-inducible protein PhoH
BZ22_2788	COG3658	cytochrome
BZ22_2789	COG1215	transferase activity, transferring glycosyl groups
BZ22_2790	COG1649	PFAM Uncharacterised BCR, COG1649
BZ22_2790	COG0726	polysaccharide deacetylase
BZ22_2791	COG0457	Tetratricopeptide repeat
BZ22_2792	COG0006	proline dipeptidase activity
BZ22_2796	COG0577	efflux transmembrane transporter activity
BZ22_2796	COG1136	(ABC) transporter
BZ22_2798	COG1136	(ABC) transporter
BZ22_2798	COG0577	efflux transmembrane transporter activity
BZ22_2801	COG0672	)-iron permease
BZ22_2803	COG2066	Belongs to the glutaminase family
BZ22_2804	COG1349	DNA-binding transcription factor activity
BZ22_2806	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZ22_2807	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ22_2816	COG2030	dehydratase
BZ22_2817	COG0427	acetyl-CoA hydrolase
BZ22_282	COG0805	protein transport
BZ22_2823	COG3188	usher protein
BZ22_2825	COG3121	Chaperone
BZ22_2828	COG0395	ABC-type sugar transport system, permease component
BZ22_2829	COG1175	transmembrane transport
BZ22_2831	COG0673	inositol 2-dehydrogenase activity
BZ22_2839	COG3328	transposase activity
BZ22_284	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZ22_2840	COG3328	transposase activity
BZ22_2855	COG4974	Belongs to the 'phage' integrase family
BZ22_2867	COG5002	protein histidine kinase activity
BZ22_2867	COG2176	DNA-directed DNA polymerase activity
BZ22_2873	COG4695	Portal protein
BZ22_288	COG1322	Protein conserved in bacteria
BZ22_289	COG0586	Pfam SNARE associated Golgi protein
BZ22_29	COG2731	YhcH YjgK YiaL family protein
BZ22_290	COG1966	Carbon starvation protein
BZ22_2907	COG2197	response regulator
BZ22_2909	COG3136	membrane protein required for alginate biosynthesis
BZ22_2913	COG1113	amino acid transport
BZ22_292	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BZ22_2921	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZ22_2921	COG0506	proline dehydrogenase activity
BZ22_2921	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BZ22_2929	COG1191	sigma factor activity
BZ22_293	COG0412	Dienelactone hydrolase
BZ22_2935	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BZ22_2936	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BZ22_2939	COG1677	Flagellar hook-basal body complex protein FliE
BZ22_2941	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BZ22_2943	COG1157	protein secretion by the type III secretion system
BZ22_2944	COG2882	bacterial-type flagellum organization
BZ22_2946	COG1580	Controls the rotational direction of flagella during chemotaxis
BZ22_2951	COG1987	bacterial-type flagellum assembly
BZ22_2955	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_2956	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_2957	COG1129	ABC transporter
BZ22_2959	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_296	COG0583	DNA-binding transcription factor activity
BZ22_2961	COG3347	Dehydrogenase
BZ22_2961	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_2962	COG2390	Transcriptional regulator
BZ22_2964	COG1256	bacterial-type flagellum assembly
BZ22_2968	COG4786	Flagellar basal body rod
BZ22_2970	COG1749	Flagellar hook protein flgE
BZ22_2971	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BZ22_2972	COG1558	bacterial-type flagellum-dependent cell motility
BZ22_2973	COG1815	bacterial-type flagellum-dependent cell motility
BZ22_2975	COG2747	anti-sigma28 factor FlgM
BZ22_2976	COG3418	PFAM FlgN family protein
BZ22_2979	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ22_2980	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BZ22_2985	COG2372	response to copper ion
BZ22_2986	COG1528	Iron-storage protein
BZ22_2989	COG1770	oligopeptidase
BZ22_299	COG0679	Auxin Efflux Carrier
BZ22_2992	COG3141	response to X-ray
BZ22_2993	COG0513	Belongs to the DEAD box helicase family
BZ22_2998	COG1760	l-serine dehydratase
BZ22_2999	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BZ22_3	COG2207	Transcriptional regulator
BZ22_300	COG0584	glycerophosphoryl diester phosphodiesterase
BZ22_3000	COG2368	4-hydroxyphenylacetate
BZ22_3003	COG3971	2-oxopent-4-enoate hydratase activity
BZ22_3005	COG3384	dioxygenase
BZ22_3006	COG1012	belongs to the aldehyde dehydrogenase family
BZ22_3009	COG1846	Transcriptional regulator
BZ22_3010	COG1253	flavin adenine dinucleotide binding
BZ22_3011	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_3011	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_3012	COG3715	PTS system
BZ22_3013	COG3716	PTS system mannose fructose sorbose family IID component
BZ22_3017	COG5002	protein histidine kinase activity
BZ22_3017	COG5001	Diguanylate cyclase
BZ22_3017	COG3447	MASE1 domain protein
BZ22_3019	COG2226	methyltransferase
BZ22_3021	COG1278	Cold shock
BZ22_3024	COG1113	amino acid transport
BZ22_3031	COG2207	Transcriptional regulator
BZ22_3033	COG1132	(ABC) transporter
BZ22_3039	COG2223	nitrite transmembrane transporter activity
BZ22_3044	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BZ22_3049	COG3122	Protein conserved in bacteria
BZ22_3053	COG0534	Mate efflux family protein
BZ22_3056	COG4948	Mandelate Racemase Muconate Lactonizing
BZ22_3058	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_3059	COG3011	Protein conserved in bacteria
BZ22_3060	COG2271	Major facilitator Superfamily
BZ22_3061	COG1470	cell adhesion involved in biofilm formation
BZ22_3061	COG1388	LysM domain
BZ22_3064	COG2925	Exonuclease
BZ22_3065	COG0531	amino acid
BZ22_3067	COG0371	Dehydrogenase
BZ22_3068	COG1129	ABC transporter
BZ22_3069	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_3071	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_3073	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BZ22_3076	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BZ22_3079	COG0140	phosphoribosyl-ATP diphosphatase activity
BZ22_3079	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BZ22_3080	COG1943	Transposase
BZ22_3082	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BZ22_3083	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BZ22_3084	COG4264	IucA IucC family
BZ22_3086	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZ22_3087	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_3088	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_3089	COG1120	ATPase activity
BZ22_3092	COG3486	L-lysine 6-monooxygenase (NADPH) activity
BZ22_3093	COG0076	glutamate decarboxylase activity
BZ22_3094	COG4114	ferric iron reductase
BZ22_3095	COG1253	flavin adenine dinucleotide binding
BZ22_3096	COG2982	Protein involved in outer membrane biogenesis
BZ22_3099	COG0489	protein tyrosine kinase activity
BZ22_31	COG0601	transmembrane transport
BZ22_3104	COG2814	Major facilitator Superfamily
BZ22_3106	COG1346	cytolysis
BZ22_3109	COG2949	membrane
BZ22_3110	COG4211	Belongs to the binding-protein-dependent transport system permease family
BZ22_3113	COG2311	Membrane
BZ22_3115	COG0477	Major facilitator Superfamily
BZ22_3116	COG0583	DNA-binding transcription factor activity
BZ22_312	COG0410	ABC transporter
BZ22_3122	COG1136	(ABC) transporter
BZ22_3124	COG0303	'Molybdopterin
BZ22_3127	COG0488	(ABC) transporter
BZ22_313	COG0411	ABC transporter
BZ22_314	COG4177	L-phenylalanine transmembrane transporter activity
BZ22_3148	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BZ22_3149	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BZ22_315	COG0559	Belongs to the binding-protein-dependent transport system permease family
BZ22_3151	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_3152	COG1024	Enoyl-CoA hydratase
BZ22_3154	COG3425	synthase
BZ22_3155	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_3156	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ22_3157	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BZ22_3159	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_316	COG0683	leucine binding
BZ22_3164	COG2920	part of a sulfur-relay system
BZ22_3168	COG1832	CoA-binding protein
BZ22_3169	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BZ22_3171	COG0210	DNA helicase
BZ22_3172	COG3304	Inner membrane component domain
BZ22_3173	COG1289	transmembrane transporter activity
BZ22_3174	COG3070	regulator of competence-specific genes
BZ22_3176	COG2885	chlorophyll binding
BZ22_3176	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BZ22_3177	COG1943	Transposase
BZ22_3179	COG1067	ATP-dependent peptidase activity
BZ22_3182	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZ22_3183	COG3009	Protein conserved in bacteria
BZ22_3184	COG3008	intermembrane lipid transfer
BZ22_3184	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BZ22_3185	COG2995	paraquat-inducible protein a
BZ22_3186	COG0488	(ABC) transporter
BZ22_3188	COG0633	Ferredoxin
BZ22_3188	COG3217	Mosc domain protein beta barrel domain protein
BZ22_319	COG2177	Part of the ABC transporter FtsEX involved in
BZ22_3191	COG0308	aminopeptidase N
BZ22_3195	COG1448	Aminotransferase
BZ22_3196	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZ22_3197	COG3108	Peptidase M15
BZ22_3198	COG2989	Protein conserved in bacteria
BZ22_32	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ22_320	COG2884	Cell division ATP-binding protein ftsE
BZ22_3200	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BZ22_3201	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
BZ22_3202	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BZ22_3203	COG3173	Aminoglycoside phosphotransferase
BZ22_3205	COG2835	tetraacyldisaccharide 4'-kinase activity
BZ22_3206	COG1278	Cold shock
BZ22_3207	COG5383	Protein conserved in bacteria
BZ22_321	COG0552	protein localization to endoplasmic reticulum
BZ22_321	COG0552	protein localization to endoplasmic reticulum
BZ22_3210	COG0658	competence protein
BZ22_3210	COG2333	competence protein COMEC
BZ22_3212	COG0539	negative regulation of cytoplasmic translation
BZ22_3218	COG0252	asparaginase activity
BZ22_3219	COG1944	ATP diphosphatase activity
BZ22_322	COG0742	ribosomal rna small subunit methyltransferase
BZ22_3220	COG2116	formate transmembrane transporter activity
BZ22_3221	COG1882	Formate acetyltransferase
BZ22_3223	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BZ22_3226	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZ22_3229	COG3107	peptidoglycan biosynthetic process
BZ22_3229	COG1674	ftsk spoiiie
BZ22_323	COG3776	membrane
BZ22_3231	COG0492	ferredoxin-NADP+ reductase activity
BZ22_3233	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BZ22_3235	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BZ22_3236	COG0542	response to heat
BZ22_3238	COG1278	Cold shock
BZ22_3240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ22_3241	COG2990	Protein conserved in bacteria
BZ22_3242	COG3593	DNA synthesis involved in DNA repair
BZ22_3243	COG2431	L-lysine efflux transmembrane transporter activity
BZ22_3245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ22_3246	COG0028	Belongs to the TPP enzyme family
BZ22_3247	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
BZ22_3248	COG0702	epimerase
BZ22_3249	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_3251	COG1605	Chorismate mutase
BZ22_3252	COG1126	abc transporter atp-binding protein
BZ22_3253	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_3254	COG4215	(ABC) transporter
BZ22_3255	COG4160	amino acid transport
BZ22_3259	COG1120	ATPase activity
BZ22_326	COG3714	YhhN family
BZ22_3260	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_3264	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_3267	COG1177	transmembrane transport
BZ22_3268	COG1176	ABC-type spermidine putrescine transport system, permease component I
BZ22_3269	COG3842	ATPase activity
BZ22_3270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BZ22_3273	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ22_3274	COG2985	domain, Protein
BZ22_3274	COG0569	domain protein
BZ22_3276	COG0671	phosphoesterase, PA-phosphatase related
BZ22_3277	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BZ22_3278	COG1349	DNA-binding transcription factor activity
BZ22_3279	COG0814	amino acid
BZ22_3280	COG1686	Belongs to the peptidase S11 family
BZ22_3281	COG2011	ABC-type metal ion transport system permease component
BZ22_3286	COG0625	glutathione transferase activity
BZ22_3287	COG4771	TonB-dependent receptor
BZ22_3289	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_329	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BZ22_3291	COG0833	amino acid
BZ22_3293	COG0583	DNA-binding transcription factor activity
BZ22_3294	COG2855	membrane
BZ22_3296	COG3188	usher protein
BZ22_3297	COG3121	Chaperone
BZ22_33	COG0444	Belongs to the ABC transporter superfamily
BZ22_3300	COG3710	Transcriptional regulator
BZ22_3301	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BZ22_3301	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ22_3301	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ22_3302	COG1105	Belongs to the carbohydrate kinase PfkB family
BZ22_3304	COG0494	nUDIX hydrolase
BZ22_3305	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_3306	COG1129	ABC transporter
BZ22_3308	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BZ22_331	COG0247	lactate metabolic process
BZ22_3313	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_3317	COG1312	Catalyzes the dehydration of D-mannonate
BZ22_3318	COG0246	Mannitol dehydrogenase
BZ22_3319	COG2186	Transcriptional regulator
BZ22_3321	COG0523	cobalamin synthesis protein
BZ22_3322	COG0671	phosphoesterase, PA-phosphatase related
BZ22_3323	COG0791	NLP P60 protein
BZ22_3324	COG2200	EAL domain
BZ22_3325	COG4166	transmembrane transport
BZ22_3326	COG4174	ABC transporter (Permease)
BZ22_3327	COG4239	(ABC) transporter, permease
BZ22_3328	COG4172	Belongs to the ABC transporter superfamily
BZ22_333	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZ22_3330	COG2814	Major facilitator Superfamily
BZ22_3331	COG1187	pseudouridine synthase activity
BZ22_3332	COG1061	Type III restriction enzyme res subunit
BZ22_3335	COG3082	Protein of unknown function (DUF1414)
BZ22_3336	COG3083	sulfuric ester hydrolase activity
BZ22_3339	COG3157	Type VI secretion system effector, Hcp
BZ22_334	COG0584	glycerophosphoryl diester phosphodiesterase
BZ22_3344	COG2723	6-phospho-beta-galactosidase activity
BZ22_3346	COG1737	Transcriptional regulator
BZ22_3350	COG3299	homolog of phage Mu protein gp47
BZ22_3358	COG4386	tail sheath protein
BZ22_336	COG0561	phosphatase activity
BZ22_3362	COG3622	Belongs to the hyi family
BZ22_3363	COG1349	DNA-binding transcription factor activity
BZ22_3364	COG0235	Class ii aldolase
BZ22_3365	COG3395	kinase activity
BZ22_337	COG2267	carboxylic ester hydrolase activity
BZ22_3374	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BZ22_3379	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BZ22_338	COG1280	lysine exporter protein (LysE YggA)
BZ22_3381	COG2223	nitrite transmembrane transporter activity
BZ22_3382	COG2198	Histidine kinase
BZ22_3382	COG0642	Histidine kinase
BZ22_3384	COG2205	protein histidine kinase activity
BZ22_3384	COG0784	Response regulator, receiver
BZ22_3389	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ22_339	COG1280	lysine exporter protein (LysE YggA)
BZ22_3392	COG0814	amino acid
BZ22_3397	COG0697	spore germination
BZ22_3399	COG1982	Orn Lys Arg decarboxylase major
BZ22_34	COG4608	Belongs to the ABC transporter superfamily
BZ22_340	COG0514	ATP-dependent DNA helicase (RecQ)
BZ22_3400	COG0531	amino acid
BZ22_3401	COG1174	glycine betaine transport
BZ22_3402	COG1125	glycine betaine transport
BZ22_3403	COG1174	glycine betaine transport
BZ22_3404	COG1732	Glycine betaine
BZ22_3405	COG2897	thiosulfate sulfurtransferase activity
BZ22_3408	COG0410	ABC transporter
BZ22_3409	COG1122	ATPase activity
BZ22_341	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
BZ22_3413	COG4807	Protein conserved in bacteria
BZ22_3416	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BZ22_3418	COG2261	transglycosylase associated protein
BZ22_342	COG2050	protein possibly involved in aromatic compounds catabolism
BZ22_3420	COG1403	HNH endonuclease
BZ22_3423	COG0277	FAD linked oxidase domain protein
BZ22_3424	COG1686	Belongs to the peptidase S11 family
BZ22_3426	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZ22_3428	COG1943	Transposase
BZ22_3429	COG0513	Belongs to the DEAD box helicase family
BZ22_3436	COG0513	Belongs to the DEAD box helicase family
BZ22_3437	COG1309	transcriptional regulator
BZ22_3439	COG1131	(ABC) transporter
BZ22_344	COG0598	Magnesium transport protein CorA
BZ22_3440	COG0842	Transport permease protein
BZ22_3441	COG0842	Transport permease protein
BZ22_3444	COG1902	pentaerythritol trinitrate reductase activity
BZ22_3448	COG2211	Major facilitator Superfamily
BZ22_3449	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BZ22_345	COG5564	TIM-barrel signal transduction protein
BZ22_3451	COG0583	DNA-binding transcription factor activity
BZ22_3452	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
BZ22_3456	COG0670	Belongs to the BI1 family
BZ22_3457	COG0314	molybdopterin synthase activity
BZ22_3458	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BZ22_346	COG5441	Belongs to the UPF0261 family
BZ22_3460	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BZ22_3462	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BZ22_3463	COG4628	conserved protein (DUF2132)
BZ22_3466	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BZ22_3467	COG2226	methyltransferase
BZ22_3472	COG0561	phosphatase activity
BZ22_3474	COG4149	molybdate abc transporter
BZ22_3475	COG0725	ABC transporter, periplasmic molybdate-binding protein
BZ22_3477	COG3585	molybdate ion transport
BZ22_3477	COG2005	Transcriptional regulator
BZ22_3478	COG1119	ATPase activity
BZ22_348	COG0210	DNA helicase
BZ22_3481	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BZ22_3482	COG1085	galactose-1-phosphate uridylyltransferase
BZ22_3484	COG2017	converts alpha-aldose to the beta-anomer
BZ22_3487	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZ22_3489	COG1230	cation diffusion facilitator family transporter
BZ22_349	COG1011	Hydrolase
BZ22_3498	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BZ22_3499	COG2885	chlorophyll binding
BZ22_350	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BZ22_3501	COG3064	Membrane
BZ22_3501	COG3064	Membrane
BZ22_3502	COG0848	biopolymer transport protein
BZ22_3503	COG0811	peptide transport
BZ22_3504	COG0824	Thioesterase
BZ22_3505	COG3790	cyd operon protein YbgE
BZ22_3506	COG4890	Cyd operon protein YbgT
BZ22_3507	COG1294	oxidase, subunit
BZ22_3508	COG1271	oxidase subunit
BZ22_3509	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BZ22_351	COG3159	Protein conserved in bacteria
BZ22_3511	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZ22_3512	COG0567	Dehydrogenase, E1 component
BZ22_3514	COG1053	succinate dehydrogenase
BZ22_3515	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BZ22_3516	COG2009	succinate dehydrogenase
BZ22_3519	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BZ22_3520	COG0497	DNA recombination
BZ22_3521	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ22_3523	COG2867	negative regulation of translational initiation
BZ22_3525	COG0582	viral genome integration into host DNA
BZ22_3526	COG2963	transposase activity
BZ22_3528	COG0596	Alpha beta hydrolase
BZ22_353	COG5567	small periplasmic lipoprotein
BZ22_3532	COG0735	belongs to the Fur family
BZ22_3536	COG1943	Transposase
BZ22_3537	COG2190	(PTS) system
BZ22_3537	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BZ22_3537	COG1263	PTS System
BZ22_3539	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BZ22_3540	COG1940	carbohydrate kinase activity
BZ22_3540	COG1846	Transcriptional regulator
BZ22_3541	COG0647	UMP catabolic process
BZ22_3542	COG0367	asparagine synthase
BZ22_3549	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZ22_355	COG3072	Adenylate cyclase
BZ22_3551	COG1702	phosphate starvation-inducible protein PhoH
BZ22_3553	COG4535	Mg2 and Co2 transporter CorC
BZ22_3554	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BZ22_3556	COG0765	amino acid transport
BZ22_3557	COG0765	amino acid transport
BZ22_3558	COG1126	abc transporter atp-binding protein
BZ22_3559	COG2888	peptidyl-tyrosine sulfation
BZ22_3562	COG1466	dna polymerase III delta subunit
BZ22_3564	COG0799	negative regulation of ribosome biogenesis
BZ22_3566	COG0768	penicillin binding
BZ22_3567	COG0772	Belongs to the SEDS family
BZ22_3568	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZ22_3569	COG1686	Belongs to the peptidase S11 family
BZ22_357	COG1587	Uroporphyrinogen-III synthase
BZ22_3573	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BZ22_3574	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BZ22_3575	COG1278	Cold shock
BZ22_3576	COG1278	Cold shock
BZ22_3577	COG2197	response regulator
BZ22_358	COG2959	enzyme of heme biosynthesis
BZ22_3581	COG5265	(ABC) transporter
BZ22_3583	COG3718	enzyme involved in inositol metabolism
BZ22_3585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_3586	COG0673	inositol 2-dehydrogenase activity
BZ22_3587	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_3588	COG1129	ABC transporter
BZ22_3589	COG1879	ABC-type sugar transport system periplasmic component
BZ22_359	COG3071	HemY protein
BZ22_3590	COG0673	inositol 2-dehydrogenase activity
BZ22_3591	COG3962	Belongs to the TPP enzyme family
BZ22_3595	COG2373	Large extracellular alpha-helical protein
BZ22_3596	COG4953	penicillin-binding protein 1C
BZ22_3597	COG3423	Transcriptional regulator
BZ22_3607	COG2850	peptidyl-arginine hydroxylation
BZ22_3608	COG3328	transposase activity
BZ22_3609	COG1187	pseudouridine synthase activity
BZ22_3614	COG0656	L-ascorbic acid biosynthetic process
BZ22_3615	COG0667	Aldo Keto reductase
BZ22_3619	COG2453	phosphatase
BZ22_3619	COG0671	phosphoesterase, PA-phosphatase related
BZ22_3620	COG2267	carboxylic ester hydrolase activity
BZ22_3622	COG4589	Belongs to the CDS family
BZ22_3623	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BZ22_365	COG1113	amino acid transport
BZ22_3659	COG4386	tail sheath protein
BZ22_3665	COG0582	viral genome integration into host DNA
BZ22_3669	COG2003	Belongs to the UPF0758 family
BZ22_3673	COG3596	GTP binding
BZ22_3685	COG0582	viral genome integration into host DNA
BZ22_3688	COG2501	S4 domain
BZ22_369	COG2244	polysaccharide biosynthetic process
BZ22_3690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZ22_3692	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BZ22_3693	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BZ22_3694	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BZ22_3695	COG4181	ATPase activity
BZ22_3696	COG2755	lipolytic protein G-D-S-L family
BZ22_3697	COG0300	oxidoreductase activity
BZ22_3698	COG3118	belongs to the thioredoxin family
BZ22_3699	COG0330	HflC and HflK could
BZ22_37	COG2188	Transcriptional regulator
BZ22_370	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BZ22_3700	COG1585	Membrane protein implicated in regulation of membrane protease activity
BZ22_3701	COG0789	Transcriptional regulator
BZ22_3702	COG2217	Heavy metal translocating P-type atpase
BZ22_3703	COG3735	TraB family
BZ22_3704	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BZ22_3707	COG0737	Belongs to the 5'-nucleotidase family
BZ22_3708	COG0737	Belongs to the 5'-nucleotidase family
BZ22_3709	COG2223	nitrite transmembrane transporter activity
BZ22_371	COG0456	acetyltransferase
BZ22_3710	COG1943	Transposase
BZ22_3711	COG2223	nitrite transmembrane transporter activity
BZ22_3712	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BZ22_3712	COG4651	solute:proton antiporter activity
BZ22_3713	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_3714	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZ22_3716	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_3719	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_372	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BZ22_3720	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BZ22_3723	COG2244	polysaccharide biosynthetic process
BZ22_3725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BZ22_3729	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZ22_3729	COG0543	2 iron, 2 sulfur cluster binding
BZ22_373	COG1088	dTDP-glucose 4,6-dehydratase activity
BZ22_3735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BZ22_3737	COG2832	Protein of unknown function (DUF454)
BZ22_3739	COG3264	Mechanosensitive ion channel
BZ22_3739	COG1196	nuclear chromosome segregation
BZ22_374	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BZ22_3740	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BZ22_3741	COG1309	transcriptional regulator
BZ22_3742	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ22_3743	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ22_3744	COG1943	Transposase
BZ22_3746	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BZ22_375	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BZ22_3750	COG3695	enzyme binding
BZ22_3751	COG3126	Type III secretion system lipoprotein chaperone (YscW)
BZ22_3752	COG1946	Acyl-CoA thioesterase
BZ22_3753	COG0004	ammonium transporteR
BZ22_3754	COG0347	Belongs to the P(II) protein family
BZ22_3755	COG1132	(ABC) transporter
BZ22_3756	COG1132	(ABC) transporter
BZ22_3757	COG1522	sequence-specific DNA binding
BZ22_376	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BZ22_3760	COG4533	DNA binding
BZ22_3762	COG0824	Thioesterase
BZ22_3763	COG1555	photosystem II stabilization
BZ22_3764	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ22_3765	COG0776	regulation of translation
BZ22_3766	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BZ22_377	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BZ22_3771	COG0271	Belongs to the BolA IbaG family
BZ22_3772	COG3056	Lipoprotein
BZ22_3773	COG2223	nitrite transmembrane transporter activity
BZ22_3775	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BZ22_3776	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BZ22_3777	COG1845	cytochrome c oxidase, subunit III
BZ22_3778	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BZ22_378	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BZ22_3780	COG2814	Major facilitator Superfamily
BZ22_3782	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BZ22_3783	COG0693	protein deglycase activity
BZ22_3786	COG0142	geranyltranstransferase activity
BZ22_3788	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BZ22_3789	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BZ22_379	COG3118	belongs to the thioredoxin family
BZ22_3792	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZ22_3792	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BZ22_3795	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BZ22_3796	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BZ22_3797	COG1862	Preprotein translocase
BZ22_38	COG3624	Phosphonate C-P lyase system protein PhnG
BZ22_3801	COG0450	alkyl hydroperoxide reductase
BZ22_3803	COG0300	oxidoreductase activity
BZ22_3804	COG0366	Alpha amylase catalytic
BZ22_3806	COG1114	Component of the transport system for branched-chain amino acids
BZ22_3808	COG5002	protein histidine kinase activity
BZ22_3809	COG0745	RESPONSE REGULATOR receiver
BZ22_3810	COG0420	3'-5' exonuclease activity
BZ22_3811	COG0419	ATPase involved in DNA repair
BZ22_3812	COG1940	carbohydrate kinase activity
BZ22_3817	COG2226	methyltransferase
BZ22_3828	COG2195	Cleaves the N-terminal amino acid of tripeptides
BZ22_383	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ22_3832	COG1477	protein flavinylation
BZ22_3836	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ22_3837	COG1805	sodium ion transport
BZ22_3838	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BZ22_3839	COG0121	glutamine amidotransferase
BZ22_3840	COG3034	peptidoglycan biosynthetic process
BZ22_3842	COG1960	acyl-CoA dehydrogenase activity
BZ22_3844	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
BZ22_3848	COG1943	Transposase
BZ22_3854	COG0436	Aminotransferase
BZ22_3857	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BZ22_386	COG3121	Chaperone
BZ22_3866	COG2814	Major facilitator Superfamily
BZ22_3867	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BZ22_3869	COG1846	Transcriptional regulator
BZ22_3870	COG1566	PFAM secretion protein HlyD family protein
BZ22_3871	COG2814	Major facilitator Superfamily
BZ22_3872	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ22_3873	COG3118	belongs to the thioredoxin family
BZ22_3875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZ22_3875	COG1042	CoA-binding domain protein
BZ22_3875	COG0045	succinate-CoA ligase (ADP-forming) activity
BZ22_3876	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BZ22_3877	COG5544	Lipoprotein
BZ22_3884	COG0542	response to heat
BZ22_3886	COG0564	pseudouridine synthase activity
BZ22_3887	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BZ22_3888	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BZ22_3889	COG1605	Chorismate mutase
BZ22_3889	COG0077	Prephenate dehydratase
BZ22_389	COG3121	Chaperone
BZ22_3890	COG0287	Prephenate dehydrogenase
BZ22_3890	COG1605	Chorismate mutase
BZ22_3891	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZ22_3892	COG3279	Response regulator of the LytR AlgR family
BZ22_3893	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BZ22_3894	COG3137	Salt-induced outer membrane protein
BZ22_3899	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BZ22_39	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BZ22_3900	COG4137	Cytochrome C assembly protein
BZ22_3901	COG4536	flavin adenine dinucleotide binding
BZ22_3904	COG1238	metal cluster binding
BZ22_3905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ22_3911	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BZ22_3919	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BZ22_3920	COG3958	Transketolase
BZ22_3921	COG3959	Transketolase, thiamine diphosphate binding domain
BZ22_3922	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_3923	COG1129	ABC transporter
BZ22_3927	COG3783	Cytochrome b(562)
BZ22_3928	COG3038	cytochrome b561
BZ22_3929	COG3381	protein complex oligomerization
BZ22_3930	COG3302	dmso reductase anchor subunit
BZ22_3931	COG0437	4 iron, 4 sulfur cluster binding
BZ22_3932	COG0243	molybdopterin cofactor binding
BZ22_3933	COG0235	Class ii aldolase
BZ22_3934	COG1349	DNA-binding transcription factor activity
BZ22_3936	COG1129	ABC transporter
BZ22_3937	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_3938	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_3939	COG3623	hexulose-6-phosphate isomerase
BZ22_3940	COG1070	Carbohydrate kinase
BZ22_3941	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BZ22_3941	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BZ22_3943	COG0024	Methionine aminopeptidase
BZ22_3945	COG4771	TonB-dependent receptor
BZ22_3947	COG1858	cytochrome C peroxidase
BZ22_3948	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_395	COG0583	DNA-binding transcription factor activity
BZ22_3952	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BZ22_3955	COG2376	Dihydroxyacetone kinase
BZ22_3956	COG1028	Short-chain dehydrogenase reductase Sdr
BZ22_3957	COG1063	alcohol dehydrogenase
BZ22_3958	COG0698	ribose 5-phosphate isomerase
BZ22_3960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BZ22_3961	COG4942	peptidase
BZ22_3961	COG1388	LysM domain
BZ22_3969	COG0529	Catalyzes the synthesis of activated sulfate
BZ22_3978	COG0720	synthase
BZ22_3979	COG0602	queuosine metabolic process
BZ22_3983	COG3956	TIGRFAM MazG family protein
BZ22_3984	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BZ22_3985	COG3437	response regulator, receiver
BZ22_3985	COG2205	protein histidine kinase activity
BZ22_3985	COG4999	Histidine kinase
BZ22_3985	COG3850	Histidine kinase
BZ22_3986	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BZ22_3990	COG2860	membrane
BZ22_3994	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BZ22_3995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BZ22_3996	COG1120	ATPase activity
BZ22_3997	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BZ22_3998	COG1643	Atp-dependent helicase
BZ22_3999	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BZ22_4	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BZ22_40	COG3626	phosphonate metabolism
BZ22_4001	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BZ22_4003	COG0617	tRNA 3'-terminal CCA addition
BZ22_4004	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BZ22_4008	COG0726	polysaccharide deacetylase
BZ22_4009	COG0842	Transport permease protein
BZ22_401	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZ22_4010	COG1131	(ABC) transporter
BZ22_4011	COG0288	reversible hydration of carbon dioxide
BZ22_4012	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BZ22_4013	COG2132	Multicopper oxidase
BZ22_4017	COG0697	spore germination
BZ22_4019	COG1049	propionate catabolic process, 2-methylcitrate cycle
BZ22_402	COG3978	acetolactate synthase activity
BZ22_4020	COG1943	Transposase
BZ22_4021	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ22_4022	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZ22_4023	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BZ22_4024	COG2186	Transcriptional regulator
BZ22_4025	COG1113	amino acid transport
BZ22_4026	COG3725	Membrane protein required for beta-lactamase induction
BZ22_4027	COG3023	N-Acetylmuramoyl-L-alanine amidase
BZ22_4029	COG4969	Belongs to the N-Me-Phe pilin family
BZ22_4030	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BZ22_4031	COG1459	type II secretion system
BZ22_4033	COG0237	dephospho-CoA kinase activity
BZ22_4036	COG1943	Transposase
BZ22_4037	COG0494	nUDIX hydrolase
BZ22_4042	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BZ22_4043	COG0849	cell division
BZ22_4044	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BZ22_4048	COG0772	Belongs to the SEDS family
BZ22_405	COG3085	chromosome segregation
BZ22_4051	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BZ22_4052	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BZ22_4053	COG0768	penicillin binding
BZ22_4054	COG3116	cell division
BZ22_4058	COG1609	Transcriptional regulator
BZ22_406	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_4060	COG0028	Belongs to the TPP enzyme family
BZ22_4061	COG1022	Amp-dependent synthetase and ligase
BZ22_4065	COG0473	3-isopropylmalate dehydrogenase activity
BZ22_4068	COG2814	Major facilitator Superfamily
BZ22_4071	COG4143	(ABC) transporter
BZ22_4072	COG1178	ABC-type Fe3 transport system permease component
BZ22_4074	COG0586	Pfam SNARE associated Golgi protein
BZ22_4075	COG0417	DNA replication proofreading
BZ22_4079	COG2885	chlorophyll binding
BZ22_4079	COG3047	cAMP biosynthetic process
BZ22_408	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_4086	COG3501	Rhs element vgr protein
BZ22_409	COG1129	ABC transporter
BZ22_4096	COG0564	pseudouridine synthase activity
BZ22_4097	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BZ22_4099	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZ22_41	COG3627	carbon phosphorus lyase activity
BZ22_410	COG1879	ABC-type sugar transport system periplasmic component
BZ22_4105	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BZ22_4107	COG2966	Psort location CytoplasmicMembrane, score
BZ22_4109	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BZ22_4110	COG0505	Belongs to the CarA family
BZ22_4113	COG1047	Peptidyl-prolyl cis-trans
BZ22_4116	COG0196	riboflavin kinase activity
BZ22_4118	COG0583	DNA-binding transcription factor activity
BZ22_4122	COG1584	GPR1 FUN34 yaaH family protein
BZ22_4125	COG0521	Mo-molybdopterin cofactor biosynthetic process
BZ22_4133	COG0745	RESPONSE REGULATOR receiver
BZ22_4134	COG3045	CreA protein
BZ22_4137	COG3708	Transcriptional regulator
BZ22_4137	COG2207	Transcriptional regulator
BZ22_4138	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
BZ22_4140	COG0741	lytic transglycosylase activity
BZ22_4143	COG2199	diguanylate cyclase activity
BZ22_4144	COG2885	chlorophyll binding
BZ22_4145	COG0488	(ABC) transporter
BZ22_4149	COG0560	Phosphoserine phosphatase
BZ22_4150	COG3726	membrane protein affecting hemolysin expression
BZ22_4154	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BZ22_4155	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BZ22_4156	COG0084	hydrolase, TatD family'
BZ22_4157	COG4667	esterase of the alpha-beta hydrolase superfamily
BZ22_4159	COG2823	Periplasmic or secreted lipoprotein
BZ22_4161	COG0456	acetyltransferase
BZ22_4162	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BZ22_4168	COG3706	GGDEF domain
BZ22_4171	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ22_4172	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BZ22_4175	COG0859	PFAM glycosyl transferase family 9
BZ22_4177	COG2390	Transcriptional regulator
BZ22_4185	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_4185	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_4185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BZ22_42	COG4107	phosphonate C-P lyase system protein PhnK
BZ22_424	COG0678	peroxiredoxin activity
BZ22_424	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ22_425	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ22_43	COG4778	phosphonate C-P lyase system protein PhnL
BZ22_430	COG1629	transport
BZ22_437	COG0527	aspartate kinase activity
BZ22_437	COG0460	homoserine dehydrogenase
BZ22_438	COG0626	cystathionine gamma-synthase activity
BZ22_439	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
BZ22_44	COG3454	Phosphonate metabolism
BZ22_440	COG4682	membrane
BZ22_442	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BZ22_444	COG1609	Transcriptional regulator
BZ22_445	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BZ22_448	COG1575	Belongs to the MenA family. Type 1 subfamily
BZ22_45	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BZ22_455	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BZ22_456	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BZ22_457	COG1494	fructose-1,6-bisphosphatase
BZ22_459	COG3152	Membrane
BZ22_46	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BZ22_462	COG0583	DNA-binding transcription factor activity
BZ22_463	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BZ22_464	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BZ22_465	COG0471	metal ion transport
BZ22_467	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BZ22_47	COG0702	epimerase
BZ22_472	COG3678	ATP-independent chaperone mediated protein folding
BZ22_473	COG0745	RESPONSE REGULATOR receiver
BZ22_474	COG2205	protein histidine kinase activity
BZ22_475	COG2169	Transcriptional regulator
BZ22_475	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BZ22_476	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BZ22_477	COG1045	serine acetyltransferase
BZ22_480	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZ22_481	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BZ22_483	COG4942	peptidase
BZ22_484	COG2861	carbohydrate metabolic process
BZ22_486	COG0156	8-amino-7-oxononanoate synthase activity
BZ22_488	COG0859	PFAM glycosyl transferase family 9
BZ22_489	COG0859	PFAM glycosyl transferase family 9
BZ22_490	COG1519	Transferase
BZ22_494	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BZ22_497	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BZ22_50	COG3842	ATPase activity
BZ22_502	COG1561	YicC-like family, N-terminal region
BZ22_51	COG0395	ABC-type sugar transport system, permease component
BZ22_514	COG2860	membrane
BZ22_515	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BZ22_517	COG1758	RNA polymerase activity
BZ22_518	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BZ22_519	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZ22_520	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BZ22_521	COG0786	glutamate:sodium symporter activity
BZ22_522	COG2233	PERMEase
BZ22_523	COG2982	Protein involved in outer membrane biogenesis
BZ22_524	COG0456	acetyltransferase
BZ22_527	COG1011	Hydrolase
BZ22_529	COG0174	glutamine synthetase
BZ22_53	COG1653	transport
BZ22_530	COG3852	Histidine kinase
BZ22_532	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BZ22_535	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ22_535	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BZ22_536	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BZ22_537	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BZ22_538	COG3084	Protein conserved in bacteria
BZ22_540	COG1763	Mo-molybdopterin cofactor biosynthetic process
BZ22_541	COG3328	transposase activity
BZ22_546	COG2186	Transcriptional regulator
BZ22_548	COG0477	Major facilitator Superfamily
BZ22_549	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_555	COG1522	sequence-specific DNA binding
BZ22_556	COG0716	FMN binding
BZ22_559	COG3312	ion transport
BZ22_569	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BZ22_57	COG3153	acetyltransferase
BZ22_571	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BZ22_572	COG0573	inorganic phosphate transmembrane transporter activity
BZ22_573	COG0581	inorganic phosphate transmembrane transporter activity
BZ22_575	COG0704	Plays a role in the regulation of phosphate uptake
BZ22_577	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BZ22_578	COG0765	amino acid transport
BZ22_579	COG0765	amino acid transport
BZ22_580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZ22_581	COG2252	PERMEase
BZ22_586	COG0706	membrane insertase activity
BZ22_589	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BZ22_592	COG0592	DNA-directed DNA polymerase activity
BZ22_593	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BZ22_594	COG0187	DNA topoisomerase II activity
BZ22_595	COG0561	phosphatase activity
BZ22_596	COG2423	ornithine cyclodeaminase activity
BZ22_597	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BZ22_598	COG0823	Involved in the tonB-independent uptake of proteins
BZ22_599	COG5645	(Lipo)protein
BZ22_6	COG4269	membrane
BZ22_603	COG3977	Valine--pyruvate aminotransferase
BZ22_605	COG0366	Alpha amylase catalytic
BZ22_608	COG2885	chlorophyll binding
BZ22_610	COG2818	Glycosylase
BZ22_614	COG2213	PTS system mannitol-specific
BZ22_614	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BZ22_616	COG3722	fumarate hydratase activity
BZ22_62	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BZ22_623	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZ22_625	COG0243	molybdopterin cofactor binding
BZ22_625	COG3383	formate dehydrogenase (NAD+) activity
BZ22_626	COG0243	molybdopterin cofactor binding
BZ22_626	COG3383	formate dehydrogenase (NAD+) activity
BZ22_627	COG0437	4 iron, 4 sulfur cluster binding
BZ22_628	COG2864	formate dehydrogenase
BZ22_631	COG3276	selenocysteine insertion sequence binding
BZ22_637	COG3274	enterobacterial common antigen metabolic process
BZ22_639	COG3188	usher protein
BZ22_640	COG3121	Chaperone
BZ22_642	COG1070	Carbohydrate kinase
BZ22_644	COG4213	ABC transporter substrate-binding protein
BZ22_646	COG4214	carbohydrate transport
BZ22_647	COG2207	Transcriptional regulator
BZ22_647	COG1609	Transcriptional regulator
BZ22_649	COG0582	viral genome integration into host DNA
BZ22_65	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BZ22_656	COG2801	Transposase and inactivated derivatives
BZ22_657	COG4604	ABC transporter, ATP-binding protein
BZ22_658	COG4605	iron ion homeostasis
BZ22_660	COG4607	ABC-type enterochelin transport system periplasmic component
BZ22_663	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BZ22_669	COG2194	sulfuric ester hydrolase activity
BZ22_670	COG2197	response regulator
BZ22_671	COG3851	Histidine kinase
BZ22_672	COG2271	Major facilitator Superfamily
BZ22_676	COG2831	hemolysin activation secretion protein
BZ22_678	COG0747	negative chemotaxis
BZ22_679	COG0601	transmembrane transport
BZ22_68	COG0513	Belongs to the DEAD box helicase family
BZ22_680	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BZ22_681	COG0444	Belongs to the ABC transporter superfamily
BZ22_682	COG4608	Belongs to the ABC transporter superfamily
BZ22_684	COG2200	EAL domain
BZ22_684	COG2199	diguanylate cyclase activity
BZ22_685	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BZ22_690	COG0612	Peptidase, M16
BZ22_691	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZ22_692	COG1942	4-Oxalocrotonate Tautomerase
BZ22_693	COG2200	EAL domain
BZ22_694	COG2982	Protein involved in outer membrane biogenesis
BZ22_695	COG2134	cdp-diacylglycerol pyrophosphatase
BZ22_696	COG1295	ribonuclease BN
BZ22_701	COG1929	Belongs to the glycerate kinase type-1 family
BZ22_702	COG2610	gluconate transmembrane transporter activity
BZ22_703	COG3835	regulator
BZ22_704	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZ22_705	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BZ22_706	COG0339	signal peptide processing
BZ22_710	COG0589	response to stress
BZ22_712	COG0306	phosphate transporter
BZ22_713	COG2081	HI0933 family
BZ22_716	COG1172	Belongs to the binding-protein-dependent transport system permease family
BZ22_717	COG1879	ABC-type sugar transport system periplasmic component
BZ22_719	COG0191	fructose-bisphosphate aldolase activity
BZ22_721	COG0745	RESPONSE REGULATOR receiver
BZ22_723	COG1741	Belongs to the pirin family
BZ22_724	COG1609	Transcriptional regulator
BZ22_725	COG2610	gluconate transmembrane transporter activity
BZ22_726	COG3265	gluconokinase activity
BZ22_730	COG2095	MarC family integral membrane protein
BZ22_731	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BZ22_736	COG3275	phosphorelay sensor kinase activity
BZ22_741	COG0058	SHG alpha-glucan phosphorylase activity
BZ22_742	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZ22_746	COG1349	DNA-binding transcription factor activity
BZ22_75	COG0195	Participates in both transcription termination and antitermination
BZ22_750	COG0058	SHG alpha-glucan phosphorylase activity
BZ22_751	COG1640	4-alpha-glucanotransferase
BZ22_758	COG1918	ferrous iron import across plasma membrane
BZ22_759	COG2183	response to ionizing radiation
BZ22_760	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ22_761	COG0745	RESPONSE REGULATOR receiver
BZ22_765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BZ22_766	COG1011	Hydrolase
BZ22_769	COG0494	nUDIX hydrolase
BZ22_772	COG5301	cellulose 1,4-beta-cellobiosidase activity
BZ22_786	COG3179	chitinase
BZ22_789	COG4382	Mu-like prophage protein Gp16
BZ22_79	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZ22_804	COG3423	Transcriptional regulator
BZ22_806	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BZ22_81	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BZ22_811	COG4796	Type ii and iii secretion system protein
BZ22_816	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BZ22_817	COG0546	phosphoglycolate phosphatase activity
BZ22_818	COG0180	Tryptophanyl-tRNA synthetase
BZ22_82	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZ22_821	COG2146	nitrite reductase [NAD(P)H] activity
BZ22_822	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BZ22_823	COG0402	S-adenosylhomocysteine deaminase activity
BZ22_827	COG1486	melibiose metabolic process
BZ22_828	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZ22_829	COG0433	COG0433 Predicted ATPase
BZ22_832	COG1289	transmembrane transporter activity
BZ22_834	COG1765	OsmC-like protein
BZ22_836	COG3157	Type VI secretion system effector, Hcp
BZ22_839	COG3954	Phosphoribulokinase
BZ22_84	COG1534	Rna-binding protein
BZ22_841	COG0429	hydrolase of the alpha beta-hydrolase fold
BZ22_843	COG4521	taurine ABC transporter
BZ22_845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BZ22_846	COG2175	clavaminate synthase activity
BZ22_848	COG1216	Glycosyl transferase, family 2
BZ22_849	COG0488	(ABC) transporter
BZ22_85	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BZ22_852	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BZ22_853	COG1047	Peptidyl-prolyl cis-trans
BZ22_855	COG0545	Peptidyl-prolyl cis-trans isomerase
BZ22_856	COG2964	Protein conserved in bacteria
BZ22_86	COG2027	D-alanyl-D-alanine carboxypeptidase
BZ22_860	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BZ22_861	COG0049	tRNA binding
BZ22_864	COG1943	Transposase
BZ22_868	COG0051	transcription antitermination factor activity, RNA binding
BZ22_87	COG0745	RESPONSE REGULATOR receiver
BZ22_873	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BZ22_875	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BZ22_876	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BZ22_878	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BZ22_879	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BZ22_88	COG0642	Histidine kinase
BZ22_887	COG1841	ribosomal large subunit assembly
BZ22_889	COG0201	protein transport
BZ22_890	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BZ22_893	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BZ22_896	COG0789	Transcriptional regulator
BZ22_897	COG3036	rescue of stalled ribosome
BZ22_899	COG0569	domain protein
BZ22_9	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BZ22_903	COG0758	DNA mediated transformation
BZ22_905	COG0551	DNA topoisomerase type I activity
BZ22_908	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BZ22_924	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BZ22_925	COG0250	Participates in transcription elongation, termination and antitermination
BZ22_936	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BZ22_938	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BZ22_943	COG1515	deoxyribonuclease V activity
BZ22_944	COG3068	Protein conserved in bacteria
BZ22_947	COG0151	Belongs to the GarS family
BZ22_959	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BZ22_960	COG2224	Isocitrate lyase
BZ22_962	COG1414	Transcriptional regulator
BZ22_967	COG0527	aspartate kinase activity
BZ22_970	COG3833	ABC-type maltose transport systems, permease component
BZ22_971	COG1175	transmembrane transport
BZ22_993	COG3501	Rhs element vgr protein
BZ22_995	COG3209	COG3209 Rhs family protein