locus-tag class description BZ19_1 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ19_100 ENOG4105BZU Histidine kinase BZ19_1000 ENOG4108535 NAD dependent epimerase/dehydratase family BZ19_1002 ENOG4105CNN ABC, transporter BZ19_1003 ENOG4105C2J ABC transporter BZ19_1004 ENOG4107SCQ Iron-containing alcohol dehydrogenase BZ19_1006 ENOG4105CUB amino acid BZ19_1007 ENOG4108RS6 transposase BZ19_1008 ENOG4105CJB Exodeoxyribonuclease I BZ19_101 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ19_1011 ENOG4105TNG K13735 adhesin invasin BZ19_1012 ENOG4105CSP Major Facilitator Superfamily BZ19_1013 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BZ19_1014 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BZ19_1016 ENOG4105DIA mandelate racemase muconate lactonizing BZ19_102 ENOG4105DXN mazG family BZ19_1020 ENOG4105UQX Mate efflux family protein BZ19_1024 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BZ19_1026 ENOG4108KX4 response regulator BZ19_1027 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BZ19_1029 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BZ19_1030 ENOG4108TSE Transferase BZ19_1033 ENOG4105U0F oligosaccharide H symporter, major facilitator superfamily (MFS) BZ19_1039 ENOG4105BZ1 (ABC) transporter BZ19_1043 ENOG4105N4N Protein of unknown function (DUF2766) BZ19_1044 ENOG4105TIK BZ19_1045 ENOG41064PC BZ19_1048 ENOG4105C85 amino acid BZ19_1051 ENOG4105VEQ Cold shock protein BZ19_1052 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ19_1053 ENOG4105DHI Methyltransferase BZ19_1055 ENOG4105BZU Histidine kinase BZ19_1059 ENOG4105F3R pts system mannose fructose sorbose family iid BZ19_106 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BZ19_1060 ENOG4105ETZ PTS System BZ19_1061 ENOG4108EQA pts system BZ19_1062 ENOG4105EE5 Membrane protein terC BZ19_1063 ENOG4108V8F Transcriptional regulator, MarR family BZ19_1066 ENOG4105C26 Dehydrogenase BZ19_1067 ENOG4107THI 3,4-dihydroxyphenylacetate 2,3-dioxygenase BZ19_107 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BZ19_1072 ENOG4105EFA 4-hydroxyphenylacetate BZ19_1073 ENOG4107UWN reductase BZ19_1074 ENOG4105EJQ L-serine dehydratase BZ19_1076 ENOG4105CRQ synthase (Component I) BZ19_1079 ENOG4105C1J atp-dependent rna helicase BZ19_1080 ENOG4105X2V dna damage-inducible protein BZ19_1083 ENOG4105CUG Oligopeptidase b BZ19_1086 ENOG4105MPK DNA polymerase III subunit theta BZ19_1087 ENOG41090A1 ferritin BZ19_1088 ENOG4105FXM Copper resistance protein BZ19_1090 ENOG4105NKT exported protein BZ19_1093 ENOG4105D00 flagellar biosynthetic protein flhB BZ19_1094 ENOG4105D7B Flagellar biosynthesis protein flha BZ19_1095 ENOG4105W13 flagellar protein BZ19_1097 ENOG4105QVD Flagella synthesis protein FlgN BZ19_1098 ENOG4105M9M anti-sigma28 factor FlgM BZ19_1099 ENOG4105CKS Flagella basal body P-ring formation protein flgA BZ19_1100 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ19_1101 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ19_1102 ENOG4105W00 Flagellar hook capping protein BZ19_1103 ENOG4105BZE flagellar hook protein, FlgE BZ19_1104 ENOG4108KPB Flagellar basal-body rod protein FlgF BZ19_1105 ENOG4105CGA flagellar basal-body rod protein FlgG BZ19_1108 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BZ19_1109 ENOG4105E1Q flagellar hook-associated protein BZ19_1110 ENOG4105DTJ flagellar hook-associated protein BZ19_1111 ENOG4105DKT Transcriptional regulator BZ19_1113 ENOG4105CNN ABC, transporter BZ19_1115 ENOG4105C2J ABC transporter BZ19_1116 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BZ19_1117 ENOG4108MGF sugar kinase BZ19_1119 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ19_1120 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ19_1121 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ19_1123 ENOG4105DD5 Flagellar motor switch protein BZ19_1124 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ19_1125 ENOG4107ZI8 flagellar basal body-associated protein flil BZ19_1126 ENOG4105WF4 Flagellar hook-length control protein BZ19_1127 ENOG4105GSA Flagellar export protein flij BZ19_1128 ENOG4108JIR Flagellum-specific ATP synthase BZ19_1129 ENOG41090PJ Flagellar assembly protein BZ19_1130 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BZ19_1131 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ19_1132 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BZ19_1136 ENOG4105DHT Metal Dependent Phosphohydrolase BZ19_1139 ENOG4105MQ3 flagellar protein FliS BZ19_1140 ENOG4105DTS flagellar hook-associated BZ19_1141 ENOG4105I03 Flagellin BZ19_1142 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ19_1143 ENOG4108M9K flagella biosynthesis protein FliZ BZ19_1145 ENOG4105EAB amino acid AbC transporter BZ19_1146 ENOG4105E5Q amino acid AbC transporter BZ19_1147 ENOG4105CDA abc transporter atp-binding protein BZ19_1150 ENOG4105C26 Dehydrogenase BZ19_1152 ENOG4105CK7 Sodium proline symporter BZ19_1158 ENOG4105C85 amino acid BZ19_116 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BZ19_1160 ENOG4108T1M outer membrane protein x BZ19_1162 ENOG4105RA2 Membrane BZ19_1163 ENOG4105XVG cytoplasmic protein BZ19_1164 ENOG4105WH1 Two component transcriptional regulator luxr family BZ19_117 ENOG4105N0Z inner membrane protein ygbE BZ19_1178 ENOG4105CDU Replicative dna helicase BZ19_1186 ENOG4105RWQ Protein of unknown function (DUF1364) BZ19_1187 ENOG4105HRS Antitermination protein BZ19_1190 ENOG4105QFS Lysis protein S homolog from lambdoid prophage BZ19_1196 ENOG4108ES9 ParB domain protein nuclease BZ19_1200 ENOG4105K4U addiction module toxin, RelE StbE family BZ19_1203 ENOG4107ZQ5 Phage-associated protein, HI1409 family BZ19_1205 ENOG41090AG Bacteriophage protein BZ19_1229 ENOG4108US3 tail fiber assembly BZ19_1233 ENOG4105ZTC transcriptional activator, Ogr delta BZ19_124 ENOG4108K5P (LipO)protein BZ19_125 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ19_1255 ENOG4105FDP GntR family transcriptional regulator BZ19_1257 ENOG4105EPC oxidoreductase BZ19_1260 ENOG4105DRW binding-protein-dependent transport systems inner membrane Component BZ19_1261 ENOG4108IJ9 (ABC) transporter BZ19_1263 ENOG4108MQF Chaperone BZ19_1265 ENOG4105CW0 outer membrane usher protein BZ19_1268 ENOG4105BZU Histidine kinase BZ19_1269 ENOG4108Q9V regulatoR BZ19_127 ENOG4108YZG isomerase BZ19_1270 ENOG4105CYC Transferase BZ19_1271 ENOG4105DJG MaoC domain protein dehydratase BZ19_1276 ENOG4107RGD Major Facilitator superfamily BZ19_1279 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ19_128 ENOG4105CPQ Dehydrogenase BZ19_1280 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BZ19_1281 ENOG4105C85 amino acid BZ19_1282 ENOG4105MVE transcriptional regulator BZ19_1283 ENOG4105CSV Glutaminase BZ19_1285 ENOG4107SJW iron permease, FTR1 BZ19_1288 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BZ19_129 ENOG4105CHR reductase BZ19_1290 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BZ19_1294 ENOG4105H1N peptidase, M24 BZ19_1295 ENOG4108TUY outer membrane protein PgaA BZ19_1296 ENOG4107BJW polysaccharide deacetylase BZ19_1297 ENOG4105CND Glycosyl transferase, family 2 BZ19_1298 ENOG4106FQ9 Biofilm PGA synthesis protein PgaD BZ19_13 ENOG4105CQ2 DNA polymerase BZ19_130 ENOG4105CMT Dihydroxyacetone kinase BZ19_1301 ENOG4105D5M phosphate starvation-inducible protein BZ19_1302 ENOG4105EWV Sodium calcium exchanger membrane region BZ19_1303 ENOG4105BZU Histidine kinase BZ19_1304 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BZ19_1315 ENOG4105CZE histidine utilization repressor BZ19_1316 ENOG4105D6T Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity) BZ19_1317 ENOG41090B9 response to stress BZ19_1319 ENOG4105CCZ Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity) BZ19_132 ENOG4105DKT Transcriptional regulator BZ19_1320 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ19_1333 ENOG4108WF3 methyltransferase BZ19_1342 ENOG4105GR3 Histidine kinase BZ19_1344 ENOG4105ENX hydrolase BZ19_1351 ENOG4105C3G gtp-binding protein BZ19_1353 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria BZ19_1354 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BZ19_1359 ENOG4105EQY Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity) BZ19_1360 ENOG4108YY7 Invasion gene expression up-regulator SirB BZ19_1361 ENOG41063JG Transcriptional regulator BZ19_1363 ENOG4105CHH sulfate transporter BZ19_1369 ENOG4105F38 ABC transporter, permease BZ19_137 ENOG4105E89 ABC transporter BZ19_1371 ENOG4108QXE glycerophosphoryl diester phosphodiesterase BZ19_1375 ENOG4107XHZ cytoplasmic chaperone TorD family protein BZ19_1376 ENOG4105F3T (LipO)protein BZ19_1378 ENOG4105D9U N-acetyltransferase BZ19_138 ENOG4105CA0 peroxidase BZ19_1381 ENOG4105CJR Integral membrane protein (MviN BZ19_1385 ENOG4106ZCM YecM protein BZ19_1389 ENOG4105WJG Glutathione BZ19_1390 ENOG41081XQ Conserved Protein BZ19_1392 ENOG4108TIT dATP pyrophosphohydrolase BZ19_1397 ENOG4105FAV ABC, transporter BZ19_1399 ENOG4105NXV High-affinity zinc uptake system protein BZ19_14 ENOG4108KF1 Membrane BZ19_140 ENOG4105D05 Receptor BZ19_1400 ENOG4105DR5 peptidase BZ19_1401 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BZ19_1402 ENOG4105CA9 Pyruvate kinase BZ19_1403 ENOG4106KNT transcriptional regulator BZ19_1404 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BZ19_1406 ENOG4108UHU Aldolase BZ19_1409 ENOG4105M4H endoribonuclease L-psp BZ19_1410 ENOG4105DVT helicase BZ19_1411 ENOG41072GX Peptidase M22 Glycoprotease BZ19_1412 ENOG4105Y4Z Outer Membrane Lipoprotein BZ19_1413 ENOG4105CEY Amp-dependent synthetase and ligase BZ19_1414 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BZ19_1415 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) BZ19_1416 ENOG4107QMS site-determining protein BZ19_1419 ENOG4105CVE Lytic murein transglycosylase BZ19_142 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ19_1420 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BZ19_1423 ENOG4105C3J Cysteine desulfurase BZ19_1429 ENOG4105ED1 spovr family BZ19_1431 ENOG4105CNH Multidrug resistance protein MdtL BZ19_1432 ENOG4105EUB pirin domain protein BZ19_1433 ENOG4105HEI LysR family (Transcriptional regulator BZ19_1436 ENOG4105CYN Serine protein kinase BZ19_1437 ENOG4105GNX MltA-interacting MipA family protein BZ19_1438 ENOG4105DSB aldose 1-epimerase BZ19_144 ENOG4107GFK fumarate BZ19_1441 ENOG4105VUT cytoplasmic protein BZ19_1442 ENOG4108RWI nicotinamidase BZ19_1443 ENOG4105HDK L-asparaginase BZ19_1444 ENOG4105D07 Signal peptide peptidase, SppA BZ19_1445 ENOG41069NU Nitroreductase BZ19_1447 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ19_1448 ENOG4105MTM Protein of unknown function (DUF1496) BZ19_1449 ENOG4105M6F mutator MutT protein BZ19_145 ENOG4105CMG Carbohydrate kinase BZ19_1450 ENOG4105CGK Exodeoxyribonuclease III BZ19_1451 ENOG4105SKE transcriptional Regulator LysR family BZ19_1455 ENOG4105CIY formyltetrahydrofolate deformylase BZ19_1457 ENOG4105I93 response regulator BZ19_1458 ENOG4105C6Y Udp-glucose 6-dehydrogenase BZ19_146 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase BZ19_1460 ENOG4107104 thymidine kinase BZ19_1461 ENOG4108EKI Dehydrogenase BZ19_1462 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BZ19_1463 ENOG4107QSI ABC, transporter BZ19_1465 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ19_1466 ENOG4105C3U ABC transporter BZ19_1467 ENOG4108JQ7 (ABC) transporter BZ19_147 ENOG4105F5R ABC transporter BZ19_1471 ENOG4108T1M outer membrane protein x BZ19_1474 ENOG4105K9H YciI-like protein BZ19_1476 ENOG410822N TonB family BZ19_1477 ENOG4105NAU thioesterase Superfamily protein BZ19_148 ENOG4105CNN ABC, transporter BZ19_1481 ENOG4105EIF outer membrane protein W BZ19_1485 ENOG4105DK0 Indole-3-glycerol phosphate synthase BZ19_1487 ENOG4105DDQ anthranilate synthase BZ19_1489 ENOG4105DB7 PHP domain protein BZ19_149 ENOG4105C2J ABC transporter BZ19_1490 ENOG4107RTD sua5 ycio yrdc ywlc family protein BZ19_1491 ENOG4105FE9 pseudouridine synthase BZ19_1492 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BZ19_1493 ENOG4105UBK short-chain dehydrogenase reductase BZ19_1494 ENOG4105ERU peptidase BZ19_1495 ENOG4105RKX Protein of unknown function (DUF2498) BZ19_1497 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BZ19_1498 ENOG4107R11 Transcriptional regulator BZ19_1500 ENOG4107QM5 aconitate hydratase BZ19_1501 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BZ19_1502 ENOG4105EYK Phosphatidylglycerophosphatase B BZ19_1503 ENOG4105Q4A inner membrane protein yciS BZ19_1504 ENOG4105CFV Tetratricopeptide repeat protein BZ19_1507 ENOG4108ZJT translation initiation factor, Sui1 BZ19_1508 ENOG41061RM osmotically inducible lipoprotein BZ19_1509 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ19_151 ENOG4105E98 transcriptional regulator DeoR family BZ19_1511 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BZ19_1512 ENOG4105VCD cytoplasmic protein BZ19_1513 ENOG4105D22 carbon starvation protein BZ19_1515 ENOG4105CSP Major Facilitator Superfamily BZ19_1516 ENOG4105EXW epimerase dehydratase BZ19_1517 ENOG4105CSM endonuclease III BZ19_1519 ENOG4108UQQ Electron transport complex BZ19_152 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BZ19_1521 ENOG4105UEI Transcriptional Regulator AraC Family BZ19_1525 ENOG4105M9B inner membrane protein ydgK BZ19_1528 ENOG4108JJA ABC, transporter BZ19_153 ENOG4107QY8 reductase BZ19_1532 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator BZ19_1534 ENOG4105CNN ABC, transporter BZ19_1536 ENOG4105D9R oxidoreductase BZ19_1537 ENOG4105DHU Bile acid BZ19_154 ENOG4105QAX Iron-sulfur BZ19_1541 ENOG4106J39 exported protein BZ19_1542 ENOG4105EIP mannose-6-phosphate isomerase BZ19_1543 ENOG4105C9Q fumarate hydratase class II BZ19_1545 ENOG4105D94 Major Facilitator Superfamily BZ19_1546 ENOG4106NZI LysR family Transcriptional regulator BZ19_1547 ENOG4105DAG ROK family BZ19_1549 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ19_155 ENOG4107KGK dmso reductase anchor subunit BZ19_1551 ENOG4105KBG Protein of unknown function (DUF1161) BZ19_1553 ENOG4105EMU Dehydrogenase BZ19_1554 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BZ19_1555 ENOG4105C26 Dehydrogenase BZ19_1557 ENOG4105DWP Membrane BZ19_1559 ENOG4105C87 Aminotransferase class I and II BZ19_156 ENOG4108NEM leader-binding protein dmsD BZ19_1560 ENOG4105DFD Na H antiporter BZ19_1561 ENOG41060NJ transcriptional regulator BZ19_1563 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ19_1564 ENOG4105CNN ABC, transporter BZ19_1565 ENOG4105C2J ABC transporter BZ19_1567 ENOG4107UWC ABC, transporter BZ19_1568 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ19_157 ENOG4105CPW cytochrome b561 BZ19_1570 ENOG4105FYV Amp nucleosidase BZ19_1575 ENOG4105C7K acetolactate synthase BZ19_1576 ENOG4105M71 acetolactate synthase 1 regulatory subunit BZ19_1577 ENOG4105PAD Hydrolase BZ19_158 ENOG4108XVM Cytochrome b(562) BZ19_1580 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ19_1581 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BZ19_1582 ENOG4105Q9Y Universal stress protein BZ19_1583 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ19_1584 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BZ19_1585 ENOG4105C5D exported protein BZ19_1586 ENOG4105D5Q Arginine ornithine antiporter BZ19_1588 ENOG4107EXC regulatoR BZ19_1589 ENOG4105JJR Histidine kinase BZ19_1590 ENOG4105CTD carboxy-peptidase BZ19_1593 ENOG4105DS1 cytochrome b561 BZ19_1595 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap BZ19_1598 ENOG4105CQ7 ATP-dependent helicase BZ19_16 ENOG4106SMU thiamine transporter membrane protein BZ19_1600 ENOG4105DKT Transcriptional regulator BZ19_1601 ENOG4105DEI Mannitol dehydrogenase BZ19_1602 ENOG4105WXT Conserved Protein BZ19_1603 ENOG410689M (LipO)protein BZ19_1604 ENOG4107H52 Dicarboxylate transport BZ19_1605 ENOG4105C5I Dehydrogenase BZ19_1606 ENOG41090X5 Heat shock protein hslJ BZ19_1608 ENOG4105KT7 mgtC SapB transporter BZ19_1610 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) BZ19_1616 ENOG4107QSI ABC, transporter BZ19_1617 ENOG4105KXI murein peptide amidase A BZ19_1618 ENOG4107S8C mandelate racemase muconate lactonizing BZ19_1619 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BZ19_162 ENOG4105C2J ABC transporter BZ19_1624 ENOG4105CM6 amino acid regulated cytosolic protein BZ19_1626 ENOG4105FM1 phage shock protein C BZ19_1627 ENOG4105YYT phage shock protein B BZ19_1628 ENOG41087YS Phage shock protein A BZ19_1629 ENOG4105E51 psp operon transcriptional activator BZ19_163 ENOG4105CNN ABC, transporter BZ19_1630 ENOG4108HIY periplasmic BZ19_1631 ENOG4108I5W peptide transport system, permease protein BZ19_1632 ENOG4108EU3 peptide transport system, permease BZ19_1633 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein BZ19_1634 ENOG4108JQ2 peptide transport system atp-binding protein BZ19_1635 ENOG4105Q4T oxidoreductase BZ19_1637 ENOG4105DUX Transporter BZ19_1638 ENOG41069YE inner membrane protein yohC BZ19_1639 ENOG4108ZR5 Conserved Protein BZ19_164 ENOG4108HHA Transketolase BZ19_1640 ENOG4108K3A Glutathione S-transferase BZ19_1644 ENOG410642K Lysozyme inhibitor BZ19_1646 ENOG4108XTF Outer Membrane Lipoprotein BZ19_1647 ENOG4108RS6 transposase BZ19_1649 ENOG4107RGM aldo keto reductase BZ19_165 ENOG4108IUS Transketolase BZ19_1650 ENOG4105XZD Fe-S protein BZ19_1651 ENOG4105DIJ Phosphoethanolamine transferase BZ19_1652 ENOG4108WUH Transcriptional regulator, TetR family BZ19_1653 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ19_1655 ENOG4108UYE Lactoylglutathione lyase BZ19_1658 ENOG4105M2J Glutaredoxin BZ19_166 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BZ19_1660 ENOG4105K4H Nlp p60 protein BZ19_1661 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ19_1664 ENOG4105F52 Transcriptional regulator BZ19_1665 ENOG4105CZQ inner membrane transport protein YdhC BZ19_1666 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BZ19_1667 ENOG4108R6K riboflavin synthase, subunit alpha BZ19_1672 ENOG4105CA9 Pyruvate kinase BZ19_1673 ENOG4105KMX major outer membrane lipoprotein BZ19_1674 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BZ19_1677 ENOG4105JRK feS assembly protein SufD BZ19_1678 ENOG4105C3K feS assembly ATPase SufC BZ19_1679 ENOG4105DIW FeS assembly protein SUFB BZ19_1680 ENOG4108Z4V iron-sulfur cluster assembly BZ19_1681 ENOG4105KA0 thioesterase Superfamily protein BZ19_1682 ENOG4105CQB FAD linked oxidase domain protein BZ19_1683 ENOG4105IPI Membrane BZ19_1684 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BZ19_1686 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ19_1688 ENOG4108QBX (LipO)protein BZ19_1696 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) BZ19_1697 ENOG4108V06 Glutathione peroxidase BZ19_17 ENOG4105DP9 ABC transporter BZ19_1700 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BZ19_1701 ENOG4105C6A phenylalanyl-tRNA synthetase (beta subunit) BZ19_1707 ENOG41087WU BZ19_1711 ENOG4105DSE periplasmic solute binding protein BZ19_1712 ENOG4105DIK (ABC) transporter BZ19_1713 ENOG4105CC5 ABC transporter BZ19_1714 ENOG4105CC5 ABC transporter BZ19_1715 ENOG4105FGM Fructosamine kinase BZ19_1716 ENOG4107PN8 YfeABCD locus regulator BZ19_1717 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 BZ19_1718 ENOG4105M5J Cupin 2, conserved barrel domain protein BZ19_1720 ENOG4105CHR reductase BZ19_1721 ENOG41061NF Pectate lyase BZ19_1722 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BZ19_1723 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BZ19_1725 ENOG4105WEM extracellular solute-binding protein BZ19_1726 ENOG4108PU9 oligogalacturonate-specific porin BZ19_1727 ENOG4107K5X Membrane-bound metal-dependent hydrolase BZ19_1728 ENOG4108ETY sodium dicarboxylate symporter BZ19_1729 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ19_1731 ENOG4105CAZ oligogalacturonide lyase BZ19_1732 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ19_1733 ENOG4105GQR Chaperone BZ19_1736 ENOG4108VEV chaperone BZ19_1737 ENOG4105H8W Fimbrial protein BZ19_174 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BZ19_1740 ENOG4105CN1 protease BZ19_1742 ENOG4108ZGC gaf domain protein BZ19_1743 ENOG4105H2K paraquat-inducible protein a BZ19_1744 ENOG4105DY2 Paraquat-inducible protein b BZ19_1751 ENOG4105WT8 Protein of unknown function (DUF1480) BZ19_1758 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ19_1762 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ19_1763 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) BZ19_1764 ENOG4108VYJ response regulator receiver protein BZ19_1766 ENOG4105BZU Histidine kinase BZ19_1767 ENOG4105C8Q Methyl-accepting chemotaxis BZ19_1768 ENOG4105C8Q Methyl-accepting chemotaxis BZ19_1771 ENOG4108V3W Chemotaxis protein, CheW BZ19_1772 ENOG4105CBS Chea signal transduction histidine kinase BZ19_1773 ENOG4105ER2 Ompa motb domain protein BZ19_1774 ENOG4107RD7 Flagellar Motor Protein, MotA BZ19_1775 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region BZ19_1777 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BZ19_1778 ENOG4105KT7 mgtC SapB transporter BZ19_1779 ENOG4105C8Q Methyl-accepting chemotaxis BZ19_1781 ENOG4105VEQ Cold shock protein BZ19_1785 ENOG4105GSJ Inner membrane protein ylaC BZ19_1786 ENOG4108XM1 transcriptional regulator AsnC family BZ19_1788 ENOG41061EV selenium-binding protein YdfZ BZ19_1789 ENOG4105D6F Phosphatase BZ19_1791 ENOG4105KVH Transcriptional regulator BZ19_1792 ENOG4105ECR NmrA family BZ19_1793 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BZ19_1795 ENOG4106NDP Transcriptional regulator BZ19_1796 ENOG4108HMX isocitrate dehydrogenase (NADP) BZ19_1797 ENOG4108R99 pseudouridine synthase BZ19_180 ENOG4107VXZ Hydrolase BZ19_1801 ENOG4107QTF adenylosuccinate lyase BZ19_1803 ENOG4105XJC Two component transcriptional regulator (Winged helix family BZ19_1805 ENOG4105EZE Cupin 4 family protein BZ19_1807 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BZ19_1809 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ19_181 ENOG4105W39 Membrane BZ19_1811 ENOG4105D60 lipoprotein releasing system transmembrane protein BZ19_1812 ENOG4108JA2 transcriptioN-repair coupling factor BZ19_1813 ENOG4107MBR 17 kDa surface antigen BZ19_1816 ENOG4105CEP NADH dehydrogenase BZ19_1821 ENOG41090DQ Lipoprotein BZ19_1822 ENOG4105K59 histidine triad (HIT) protein BZ19_1823 ENOG4105F9E Shikimate 5-dehydrogenase BZ19_1824 ENOG4105CI1 PTS System BZ19_1825 ENOG4105F8V Hydrolase, tatD family BZ19_1826 ENOG4107QRG dna polymerase iii BZ19_1828 ENOG4105HHA aminodeoxychorismate lyase BZ19_1829 ENOG4105YAZ 4-amino-4-deoxychorismate lyase BZ19_1830 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ19_1832 ENOG4105CHR reductase BZ19_1833 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ19_1836 ENOG4105VGS 50s ribosomal protein l32 BZ19_1837 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BZ19_1839 ENOG4105EI2 Pseudouridine synthase BZ19_184 ENOG4108JU6 CBS domain protein BZ19_1841 ENOG4107QQB Ribonuclease E BZ19_1842 ENOG41067V3 Antibiotic biosynthesis monooxygenase BZ19_1845 ENOG4105PVA Biofilm formation regulatory protein BssS BZ19_1848 ENOG4105DSF transport protein BZ19_185 ENOG4106KVJ cytochrome C assembly protein BZ19_1851 ENOG4105D1S lipid A biosynthesis BZ19_1852 ENOG4105DUX Transporter BZ19_1853 ENOG4105NAC (LipO)protein BZ19_1854 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) BZ19_1855 ENOG4105DJ9 glucan biosynthesis protein BZ19_1856 ENOG4105EIK Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane (By similarity) BZ19_186 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BZ19_1860 ENOG4105VJY transcriptional regulator BZ19_1861 ENOG4107YC3 synthase BZ19_1862 ENOG4105ETT transcriptional Regulator, LysR family BZ19_1864 ENOG4105C54 Major Facilitator superfamily BZ19_1866 ENOG4105CPC Aldo Keto reductase BZ19_1867 ENOG4108Y1S CRISPR-associated protein, Csy4 family BZ19_1868 ENOG4105M6W Crispr-associated protein, Csy3 family BZ19_1869 ENOG4105DZX CRISPR-associated protein, Csy2 family BZ19_1870 ENOG4105ENG CRISPR-associated protein, Csy1 family BZ19_1871 ENOG4107IIZ CRISPR-associated helicase, Cas3 BZ19_1872 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) BZ19_1873 ENOG4105CUY Mechanosensitive ion channel BZ19_1877 ENOG4105HY2 Glycosidase related protein BZ19_1878 ENOG4105DRS transport system, permease BZ19_1881 ENOG4105ETE Transcriptional regulator (LacI family BZ19_1883 ENOG4108IJ9 (ABC) transporter BZ19_1889 ENOG4105CKT filamentous hemagglutinin BZ19_1890 ENOG4105D5K Hemolysin activator protein BZ19_1891 ENOG4105E3J oxidoreductase BZ19_1892 ENOG4105DVW rieske (2Fe-2S) BZ19_1893 ENOG4105C94 Transporter BZ19_1895 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BZ19_1896 ENOG4105EJC lysr family transcriptional regulator BZ19_1897 ENOG4105FKQ transcriptional regulator BZ19_1898 ENOG4105CNN ABC, transporter BZ19_1899 ENOG4105C2J ABC transporter BZ19_1900 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ19_1901 ENOG4105CPQ Dehydrogenase BZ19_1905 ENOG4108T1M outer membrane protein x BZ19_191 ENOG4108RS6 transposase BZ19_1911 ENOG4107R0W ABC transporter BZ19_1912 ENOG4105E5Q amino acid AbC transporter BZ19_1913 ENOG4105CDA abc transporter atp-binding protein BZ19_1914 ENOG4107SDU Methyl-accepting chemotaxis BZ19_1916 ENOG4105RC8 Reduces the permeability of the outer membrane to copper. Seems to be involved in the regulation of biofilm formation. May decrease biofilm formation by repressing cell-cell interaction and cell surface interaction BZ19_1917 ENOG4108MTB glycosyl transferase family BZ19_1918 ENOG4105CEY Amp-dependent synthetase and ligase BZ19_192 ENOG4108NE3 Salt-induced outer membrane protein BZ19_1920 ENOG4108IPT Naphthoate synthase BZ19_1923 ENOG4105E4F Isochorismate synthase BZ19_1925 ENOG4105TNS Conserved Protein BZ19_1927 ENOG4105C01 Dihydroxy-acid dehydratase BZ19_1928 ENOG4105C5I Dehydrogenase BZ19_1929 ENOG4105K2J Transcriptional regulator BZ19_193 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ19_1930 ENOG4105F32 YngK protein BZ19_1931 ENOG4105CHR reductase BZ19_1932 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ19_1933 ENOG4108R66 Conserved Protein BZ19_1936 ENOG4105C8S subunit m BZ19_1937 ENOG4105D65 subunit l BZ19_1939 ENOG4107UFS subunit j BZ19_194 ENOG4108NEV two component transcriptional regulator, LytTR family BZ19_1942 ENOG4108IEH NADH dehydrogenase subunit g BZ19_1943 ENOG4107QIZ NADH dehydrogenase BZ19_1944 ENOG4105GKE subunit e BZ19_1946 ENOG4105ES3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) BZ19_1948 ENOG4107NQ8 LysR family Transcriptional regulator BZ19_195 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ19_1950 ENOG4105CHM Aminotransferase BZ19_1953 ENOG4107QWE )-transporter BZ19_1954 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 BZ19_1958 ENOG4105C6K Malic enzyme BZ19_1959 ENOG4107P2S Transcriptional regulator BZ19_1962 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BZ19_1963 ENOG4105PTV Nudix Hydrolase BZ19_1964 ENOG4108RE9 Phosphodiesterase BZ19_1966 ENOG4105ECP epimerase BZ19_1967 ENOG4108JEH abc transporter atp-binding protein BZ19_1968 ENOG4106YG3 ABC transporter BZ19_1969 ENOG4105DSP amino acid AbC transporter BZ19_1970 ENOG4105E89 ABC transporter BZ19_1971 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BZ19_1972 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BZ19_1973 ENOG4105E96 Colicin v production protein BZ19_1974 ENOG4108S3P Sporulation domain protein BZ19_1975 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BZ19_1977 ENOG4105DQR SNARE associated Golgi BZ19_1979 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ19_198 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA BZ19_1982 ENOG410631K Membrane BZ19_1983 ENOG4106WZ1 flagella biosynthesis regulator BZ19_1986 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ19_1988 ENOG4105MH2 YfcL protein BZ19_1989 ENOG4108BPE -transporting atpase BZ19_199 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BZ19_1990 ENOG4105EJ9 Membrane BZ19_1993 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BZ19_1995 ENOG4108BY2 phosphohistidine phosphatase BZ19_1998 ENOG4105KZW UPF0381 protein BZ19_1999 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BZ19_2 ENOG4105CS6 Rhs element vgr protein BZ19_20 ENOG4105S8Q sugar efflux transporter BZ19_200 ENOG4105C34 Pseudouridine synthase BZ19_2000 ENOG410903C (LipO)protein BZ19_2001 ENOG4105KWW Biogenesis protein BZ19_2002 ENOG4105KWW Biogenesis protein BZ19_2003 ENOG4107QX9 Thiol disulfide interChange protein BZ19_2004 ENOG4105DA4 cytochrome c-type biogenesis protein BZ19_2006 ENOG4105X3C heme exporter protein BZ19_2007 ENOG41060IM Heme exporter protein BZ19_2008 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BZ19_201 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BZ19_2015 ENOG4108V0P LemA family BZ19_2017 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BZ19_202 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ19_2023 ENOG4105CS6 Rhs element vgr protein BZ19_2032 ENOG4105CW0 outer membrane usher protein BZ19_2033 ENOG4105GQR Chaperone BZ19_2035 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ19_2045 ENOG4105CVE Lytic murein transglycosylase BZ19_2050 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ19_2053 ENOG4107QY8 reductase BZ19_2054 ENOG4105QAX Iron-sulfur BZ19_2055 ENOG4107KGK dmso reductase anchor subunit BZ19_2056 ENOG4108NEM leader-binding protein dmsD BZ19_2058 ENOG4107Y60 (LipO)protein BZ19_2060 ENOG4106B0W Curli production assembly transport component CsgG BZ19_2062 ENOG4108VKM cytochrome b561 BZ19_2063 ENOG4105CHM Aminotransferase BZ19_2064 ENOG41072TH Protein of unknown function (DUF1479) BZ19_2067 ENOG4105C5Q Transcriptional regulator BZ19_2068 ENOG4105CPC Aldo Keto reductase BZ19_2071 ENOG4105D9N nucleoside BZ19_208 ENOG4105T42 (LipO)protein BZ19_2082 ENOG4105VRT cytoplasmic protein BZ19_2085 ENOG4105EXN Sulfate transport protein CysZ BZ19_2086 ENOG4105C6T cysteine synthase BZ19_2087 ENOG4105KZ7 phosphocarrier protein hpr BZ19_2089 ENOG4105C5Y PTS System BZ19_209 ENOG4105JIM Phosphatidylserine synthase BZ19_2090 ENOG4105E0F Histidine kinase BZ19_2091 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ19_2092 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ19_2095 ENOG4105E1V na solute symporter BZ19_2097 ENOG4107RAQ aminopeptidase BZ19_2098 ENOG4105C87 Aminotransferase class I and II BZ19_210 ENOG4105CD5 CoA-binding domain protein BZ19_2100 ENOG41062D9 Histidine kinase BZ19_2101 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ19_2102 ENOG4105C6T cysteine synthase BZ19_2104 ENOG4105ECW sulfate abc transporter BZ19_2105 ENOG4108I5D sulfate abc transporter BZ19_2106 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein BZ19_2108 ENOG4105QEK Transcriptional regulator BZ19_2109 ENOG4108R66 Conserved Protein BZ19_211 ENOG4106IUH DTW domain containing protein BZ19_2113 ENOG4105EZR dyp-type peroxidase family protein BZ19_2114 ENOG4105E7K (LipO)protein BZ19_2115 ENOG4105H4F exported protein BZ19_212 ENOG4105K63 Thioredoxin BZ19_2125 ENOG4105C6K Malic enzyme BZ19_2127 ENOG4105CUW cytochrome C-TYPE protein BZ19_2128 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) BZ19_213 ENOG4105EIB trna rrna methyltransferase BZ19_2130 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase BZ19_2131 ENOG4108ZNS ferredoxin-type protein NapF BZ19_2132 ENOG4105WH1 Two component transcriptional regulator luxr family BZ19_2134 ENOG4105BZS acriflavin resistance protein BZ19_2136 ENOG4105S2T inner membrane protein YbcI BZ19_2137 ENOG4105C4X radical SAM domain protein BZ19_2138 ENOG4105ENH Sulfatase BZ19_2139 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ19_214 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ19_2140 ENOG4107Z33 ABC transporter, permease BZ19_2141 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC BZ19_2143 ENOG4105KUZ arsenate reductase BZ19_2149 ENOG4105CGZ zinc metallopeptidase BZ19_215 ENOG4105CW7 secretion protein, HlyD family BZ19_2151 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ19_2153 ENOG4105RH4 Glycine cleavage system transcriptional repressor BZ19_2154 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BZ19_2158 ENOG4105C02 permease BZ19_2159 ENOG4105ERG peptidase m48, ste24p BZ19_216 ENOG4105NTK Transcriptional repressor Mpra BZ19_2160 ENOG4105K89 arsenate reductase BZ19_2162 ENOG4105C2W permease BZ19_2163 ENOG4108RS6 transposase BZ19_2166 ENOG4108V3E phosphoribosylglycinamide formyltransferase BZ19_2167 ENOG4108MK9 spermidine N(1)-acetyltransferase BZ19_2168 ENOG4108C80 FliB family BZ19_217 ENOG4105ZED uncharacterized protein ygaH BZ19_2170 ENOG4105E2Z phosphate ABC transporter (Permease BZ19_2171 ENOG4105C8U phosphate abc transporter BZ19_2172 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BZ19_2173 ENOG4105C9X ppx gppa phosphatase BZ19_2174 ENOG4105CJW magnesium transporter BZ19_2175 ENOG4105R8A Heat shock protein BZ19_2177 ENOG4105NRK Binding-protein-dependent transport systems, inner membrane component BZ19_2178 ENOG4105F38 ABC transporter, permease BZ19_218 ENOG4108UMN azlc family BZ19_2180 ENOG4108JPW Aminotransferase BZ19_2182 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ19_2187 ENOG4105EB3 Histidine kinase BZ19_2188 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ19_2189 ENOG4105KWI UPF0339 protein BZ19_219 ENOG4105EQ0 Major Facilitator superfamily BZ19_2190 ENOG4105CFP Peptidase U32 BZ19_2192 ENOG4108ZGU inhibitor of vertebrate lysozyme BZ19_2194 ENOG4105DWF phosphomethylpyrimidine kinase BZ19_2202 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ19_2204 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BZ19_2206 ENOG4105VPD cellular component movement BZ19_2209 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ19_2210 ENOG4105N21 Membrane BZ19_2218 ENOG4108MGN ATP-binding component of a transport system BZ19_2219 ENOG4108MGN ATP-binding component of a transport system BZ19_2220 ENOG4105YYA enhanced serine sensitivity protein SseB BZ19_2222 ENOG4105WVQ Fe-S assembly protein IscX BZ19_2223 ENOG4108ZIT Ferredoxin, 2FE-2S BZ19_2224 ENOG4105C9I Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB BZ19_2227 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BZ19_2228 ENOG4105C3J Cysteine desulfurase BZ19_2232 ENOG4105D7X high-affinity nickel-transporter BZ19_2233 ENOG41065CD Exported protein BZ19_2234 ENOG4105D8G Major Facilitator superfamily BZ19_2235 ENOG4108MN2 Stationary phase inducible protein CsiE BZ19_2238 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ19_2239 ENOG4108M21 BZ19_224 ENOG4105F87 Dehydratase BZ19_2240 ENOG4108YZA Nitrogen regulatory protein pii BZ19_2241 ENOG4105C4K Nad synthetase BZ19_2242 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ19_2243 ENOG4108SKK alpha helix protein BZ19_2244 ENOG4107WP9 Histidine kinase BZ19_2249 ENOG4108Z6B deaminase BZ19_2250 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB BZ19_2252 ENOG4106G6Q Transcriptional regulator BZ19_2253 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BZ19_2255 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) BZ19_2259 ENOG4105C3F Signal peptidase i BZ19_226 ENOG4105E5Q amino acid AbC transporter BZ19_2262 ENOG4105WMJ Positive regulator of sigma E, RseC MucC BZ19_2263 ENOG4105VQK sigma E regulatory protein, MucB RseB BZ19_2264 ENOG41069PW sigma-e factor negative regulatory protein BZ19_2266 ENOG4108IYU L-aspartate oxidase BZ19_2268 ENOG4105C1J atp-dependent rna helicase BZ19_2279 ENOG4107R7A Allophanate hydrolase subunit 2 BZ19_228 ENOG4105C5R Aminotransferase BZ19_2280 ENOG4105P4J Allophanate hydrolase, subunit 1 BZ19_2282 ENOG4107QNR UPF0135 protein BZ19_2283 ENOG4107RF4 Phosphodiesterase BZ19_2284 ENOG4105CVP deoxyribo-dipyrimidine photolyase BZ19_2285 ENOG4107SEY Conserved Protein BZ19_2286 ENOG4105XIQ Protein of unknown function (DUF2517) BZ19_2290 ENOG4105C08 Histidine kinase BZ19_2291 ENOG4105EEX Two component transcriptional regulator (Winged helix family BZ19_2294 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 BZ19_2299 ENOG4105EZV Transcriptional regulator BZ19_23 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BZ19_2300 ENOG4105VCP PTS System BZ19_2301 ENOG4105CK1 PTS System BZ19_2302 ENOG4105VZJ PTS System BZ19_2304 ENOG41086WQ Protein CrcB homolog BZ19_2305 ENOG4107SVH Potassium channel protein BZ19_2306 ENOG4105XXV Acid-resistance protein BZ19_231 ENOG4105CHM Aminotransferase BZ19_2310 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) BZ19_2317 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) BZ19_2318 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) BZ19_2319 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ19_2320 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ19_2321 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BZ19_2322 ENOG4105VEQ Cold shock protein BZ19_2324 ENOG4108SAJ Protein of unknown function (DUF1198) BZ19_2325 ENOG4108WMJ Protein of unknown function (DUF2002) BZ19_2330 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ19_2331 ENOG4108IJ7 Glycine betaine BZ19_2332 ENOG4108HQS Glycine betaine BZ19_2333 ENOG4105GIJ Glycine betaine BZ19_2335 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BZ19_2337 ENOG4108JDX DNA polymerase iii, epsilon subunit BZ19_2339 ENOG4105D1A Methyltransferase BZ19_2341 ENOG4105E9H Lytic Murein transglycosylase BZ19_2344 ENOG4105CV8 reductase BZ19_2350 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BZ19_2352 ENOG4108UMI ABC transporter, permease BZ19_2353 ENOG4105D01 (LipO)protein BZ19_2354 ENOG4108R8X outer membrane lipoprotein BZ19_2355 ENOG4108R96 Methyltransferase, YaeB family BZ19_2357 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BZ19_2358 ENOG4108YZN class I peptide chain release factor BZ19_2359 ENOG4108VWS Yaeq family BZ19_2361 ENOG4105M1T rho-binding antiterminator BZ19_2364 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BZ19_2366 ENOG4105C0B DNA polymerase III (alpha subunit) BZ19_2368 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BZ19_2372 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) BZ19_2374 ENOG4105DZP Membrane-associated zinc metalloprotease BZ19_2375 ENOG4105KNE Phosphatidate cytidylyltransferase BZ19_2376 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BZ19_2382 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BZ19_2386 ENOG4105QDK Flavodoxin BZ19_2387 ENOG4105DR9 pseudouridine synthase BZ19_2388 ENOG4105WP7 tRNA pseudouridine synthase C BZ19_239 ENOG4106YJS accessory processing protein BZ19_2391 ENOG4105EWT decarboxylase family BZ19_2394 ENOG4105M08 Membrane BZ19_2395 ENOG4105ETT transcriptional Regulator, LysR family BZ19_2396 ENOG4105C9B Cysteine desulfurase BZ19_2397 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BZ19_2398 ENOG4105CUZ uba thif-type nad fad binding protein BZ19_2399 ENOG4105CA3 membrane-bound lytic murein transglycosylase BZ19_2403 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ19_2405 ENOG4107QYX exodeoxyribonuclease v alpha BZ19_2406 ENOG4107QKA exodeoxyribonuclease V beta BZ19_2407 ENOG4107QXK peptidase BZ19_2408 ENOG4105DSY exodeoxyribonuclease V, gamma BZ19_241 ENOG4107QPN acyl-Coa dehydrogenase BZ19_2416 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BZ19_2419 ENOG4105CPC Aldo Keto reductase BZ19_2425 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BZ19_2426 ENOG41060NJ transcriptional regulator BZ19_2427 ENOG4105F27 Major Facilitator BZ19_2428 ENOG4105RQF LysR family Transcriptional regulator BZ19_2429 ENOG4105EJC lysr family transcriptional regulator BZ19_243 ENOG4105F7V ErfK ybiS ycfS ynhG family protein BZ19_2431 ENOG4105C8Q Methyl-accepting chemotaxis BZ19_244 ENOG4105E7A Glutamine amidotransferase BZ19_2444 ENOG4105D7Q type ii secretion system BZ19_2445 ENOG4107QHF type ii secretion system protein e BZ19_2449 ENOG4107B2H carbonic anhydrase BZ19_2454 ENOG4105CBG Sulfatase BZ19_2455 ENOG4105E98 transcriptional regulator DeoR family BZ19_2456 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of BZ19_2457 ENOG4105E70 isomerase BZ19_2458 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB BZ19_2459 ENOG4105ETZ PTS System BZ19_246 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ19_2460 ENOG4105F3R pts system mannose fructose sorbose family iid BZ19_2461 ENOG4108YTN IIa component BZ19_2462 ENOG4105CE4 GlcNAc 6-P deacetylase BZ19_2463 ENOG4105CHR reductase BZ19_2465 ENOG4105C4X radical SAM domain protein BZ19_2466 ENOG4105ENH Sulfatase BZ19_2468 ENOG4105D2N Aldolase BZ19_247 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BZ19_2471 ENOG4105ETE Transcriptional regulator (LacI family BZ19_2472 ENOG4105DPW Major facilitator superfamily MFS_1 BZ19_2474 ENOG4105ETE Transcriptional regulator (LacI family BZ19_2476 ENOG4105CI1 PTS System BZ19_2477 ENOG4105C4C beta-galactosidase BZ19_2479 ENOG4105EG2 ABC transporter, permease BZ19_2481 ENOG4107FKK extracellular solute-binding protein family 1 BZ19_2484 ENOG4105CNN ABC, transporter BZ19_2485 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ19_2487 ENOG4108UY0 (LipO)protein BZ19_2488 ENOG4105NTW Transcriptional regulator BZ19_25 ENOG41064T2 transcriptional regulator, lysR family BZ19_2504 ENOG4105WJ3 XRE family Transcriptional regulator BZ19_2505 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation BZ19_2508 ENOG4105DFP Integrase BZ19_251 ENOG4105CJ2 (LipO)protein BZ19_2512 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BZ19_2513 ENOG4105T95 Thiol disulfide interChange protein BZ19_2514 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ19_2515 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) BZ19_2516 ENOG4105CT7 inner membrane cred family protein BZ19_2517 ENOG4105EB3 Histidine kinase BZ19_2518 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ19_2519 ENOG4105Y75 tpr repeat protein BZ19_2522 ENOG4108UT2 hemolysin iii BZ19_2529 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ19_2530 ENOG4105D0A hydroxylase BZ19_2531 ENOG4107RAQ aminopeptidase BZ19_2534 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BZ19_2535 ENOG4108JQ1 Dehydrogenase BZ19_2536 ENOG4105E66 phosphoriboisomerase A BZ19_2538 ENOG4105MPN Membrane BZ19_2540 ENOG4105D64 Mechanosensitive ion channel BZ19_2541 ENOG4105D2N Aldolase BZ19_2544 ENOG4105CV1 Transketolase (EC 2.2.1.1) BZ19_2545 ENOG4108K0D peptidase, M48 BZ19_2547 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BZ19_255 ENOG4105CIN aminoacyl-histidine dipeptidase BZ19_2551 ENOG4105RWS endonuclease I BZ19_2552 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BZ19_2553 ENOG4105D7Z glutathione synthase BZ19_2556 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) BZ19_2558 ENOG4105CZX twitching motility protein BZ19_2559 ENOG4105DFA alanine racemase domain protein BZ19_2560 ENOG4105II7 pyrroline-5-carboxylate reductase BZ19_2561 ENOG4108VIA integral membrane protein BZ19_2563 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BZ19_2564 ENOG4105CSA Coproporphyrinogen iii oxidase BZ19_2565 ENOG4105EUK rtx toxin RtxA BZ19_2566 ENOG4105K33 Periplasmic Protein BZ19_2567 ENOG4105CSV Glutaminase BZ19_2568 ENOG41090ED Protein with unknown function (DUF469) BZ19_2570 ENOG4105CEN a g-specific adenine glycosylase BZ19_2575 ENOG4105CNN ABC, transporter BZ19_2576 ENOG4105C2J ABC transporter BZ19_2577 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ19_2578 ENOG4105CXN decarboxylase BZ19_26 ENOG4108IQE Amp-dependent synthetase and ligase BZ19_2606 ENOG4108ZG0 Ompa motb domain protein BZ19_2617 ENOG4106H6R UPF0380 protein BZ19_2623 ENOG4105H5P transposase BZ19_2625 ENOG4105TS0 gtp-binding protein BZ19_2626 ENOG4108KZE transcriptional regulator BZ19_2629 ENOG4106J9S Prophage BZ19_2630 ENOG4106H6R UPF0380 protein BZ19_2632 ENOG4105MFG Antirestriction protein BZ19_2633 ENOG4105W5Q DNA repair protein (RadC BZ19_2636 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles BZ19_2652 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ19_2654 ENOG4105CDV Ompa motb domain protein BZ19_266 ENOG4105F2W methyltransferase BZ19_2671 ENOG4105DUU IucA IucC family protein BZ19_2672 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ19_2674 ENOG4105CT4 transporter BZ19_2676 ENOG4105ETE Transcriptional regulator (LacI family BZ19_2677 ENOG4105C8P )-transporter BZ19_2678 ENOG41062WK cellular response to acidity BZ19_2683 ENOG4105CNA YD repeat protein BZ19_2685 ENOG4105CNA YD repeat protein BZ19_2687 ENOG4105CS6 Rhs element vgr protein BZ19_2690 ENOG4107EFN gluconate transport system permease 3 BZ19_2694 ENOG4105BZ1 (ABC) transporter BZ19_27 ENOG4105C7K acetolactate synthase BZ19_2700 ENOG4105C0W non-ribosomal peptide synthetase BZ19_2701 ENOG4105C0W non-ribosomal peptide synthetase BZ19_2702 ENOG4107ZSV Receptor BZ19_2703 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BZ19_2704 ENOG4105CFC Transporter BZ19_2708 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway BZ19_271 ENOG4105DKQ ROK family BZ19_2719 ENOG4108XTF Outer Membrane Lipoprotein BZ19_272 ENOG4105EYH Exonuclease BZ19_2723 ENOG4107RD7 Flagellar Motor Protein, MotA BZ19_2729 ENOG410804A Flagellar hook-associated 2 domain-containing protein BZ19_273 ENOG4107RH8 nuclease SbcCD subunit D BZ19_2731 ENOG4105I03 Flagellin BZ19_2732 ENOG4108M3R transcriptional activator CadC BZ19_2736 ENOG4105E1Q flagellar hook-associated protein BZ19_2738 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BZ19_274 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BZ19_2740 ENOG4105CGA flagellar basal-body rod protein FlgG BZ19_2741 ENOG4108KPB Flagellar basal-body rod protein FlgF BZ19_2742 ENOG4105BZE flagellar hook protein, FlgE BZ19_2743 ENOG4105W00 Flagellar hook capping protein BZ19_2744 ENOG4108ZC9 flagellar basal-body rod protein flgc BZ19_2745 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BZ19_2746 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA BZ19_275 ENOG4105BZU Histidine kinase BZ19_2750 ENOG4108JIR Flagellum-specific ATP synthase BZ19_2753 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BZ19_2755 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ19_2757 ENOG4105DD5 Flagellar motor switch protein BZ19_2758 ENOG4105CN7 Flagellar biosynthetic protein FliP BZ19_2759 ENOG4105VS8 Flagellar biosynthetic protein fliq BZ19_2760 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BZ19_2761 ENOG4105D00 flagellar biosynthetic protein flhB BZ19_2766 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein BZ19_2768 ENOG4106P2F Pfam:Pili_assembly_C BZ19_2769 ENOG4106PG1 outer membrane usher protein BZ19_277 ENOG4105CWM branched-chain amino acid transport system II carrier protein BZ19_2771 ENOG4105E03 chitinase BZ19_2772 ENOG4108M1A Chitin-binding protein BZ19_278 ENOG4105C85 amino acid BZ19_279 ENOG4107R28 alpha amylase, catalytic region BZ19_2790 ENOG4108ZZF transport protein (ExbD) BZ19_2792 ENOG4105CWK Biopolymer transport protein, ExbB BZ19_2793 ENOG4105C28 cystathionine BZ19_2794 ENOG4108K81 inner membrane protein YghB BZ19_2795 ENOG4105CF7 AraC family transcriptional regulator BZ19_2796 ENOG4108I6A alcohol dehydrogenase BZ19_2797 ENOG4105CV8 reductase BZ19_28 ENOG4108ZP8 Acetolactate synthase small subunit BZ19_280 ENOG4105CHR reductase BZ19_2801 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) BZ19_2802 ENOG4107S7E 1-acyl-sn-glycerol-3-phosphate acyltransferase BZ19_2803 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ19_2804 ENOG4105NF4 modulator of drug activity BZ19_2805 ENOG4105CR8 Transcriptional regulator BZ19_2806 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ19_2807 ENOG4105IPS esterase BZ19_2808 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BZ19_2809 ENOG4108SX3 cytoplasmic protein BZ19_2810 ENOG41087AY ADP-Ribose pyrophosphatase BZ19_2811 ENOG4105DFG type I secretion outer membrane protein BZ19_2814 ENOG4106032 Glutathionylspermidine synthase BZ19_2815 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BZ19_2817 ENOG4105W0Z cytoplasmic protein BZ19_2818 ENOG4105DVH amino acid BZ19_282 ENOG4108RS6 transposase BZ19_2821 ENOG4105I7R Adenylate cyclase BZ19_2822 ENOG4106MWK domain protein BZ19_2825 ENOG4107ZVW dihydroneopterin aldolase BZ19_2828 ENOG4105VCC 30S ribosomal protein S21 BZ19_2829 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BZ19_283 ENOG4105D3R alkyl hydroperoxide reductase BZ19_2830 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ19_2860 ENOG4105ED4 portal protein BZ19_2862 ENOG4108KQY BZ19_2866 ENOG4105VZ1 Replication Protein BZ19_287 ENOG4105VIE preprotein translocase, subunit YajC BZ19_2874 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ19_2878 ENOG4105GMB type VI secretion system effector, hcp1 family BZ19_288 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ19_2884 ENOG4105KME endoribonuclease L-psp BZ19_2888 ENOG4105CHM Aminotransferase BZ19_289 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BZ19_2891 ENOG4105J12 Multidrug resistance protein mdtN BZ19_2892 ENOG4108MI0 Resistance protein BZ19_2894 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ19_2896 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BZ19_2898 ENOG4108IJG ABC transporter substrate-binding protein BZ19_2899 ENOG4107KJX Transcriptional regulator BZ19_29 ENOG4107B7Y DNA-binding transcriptional regulator FruR BZ19_2900 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 BZ19_2905 ENOG4105CKT filamentous hemagglutinin BZ19_2907 ENOG4105CKT filamentous hemagglutinin BZ19_2914 ENOG4105CKT filamentous hemagglutinin BZ19_2919 ENOG4105CKT filamentous hemagglutinin BZ19_292 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BZ19_2920 ENOG4105D5K Hemolysin activator protein BZ19_2921 ENOG4108M24 von Willebrand factor, type A BZ19_2924 ENOG4108M24 von Willebrand factor, type A BZ19_2927 ENOG4108YK4 Acid-resistance membrane protein BZ19_2928 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BZ19_2931 ENOG4108VKG metal-dependent hydrolase BZ19_2932 ENOG4105EE0 oxidoreductase BZ19_2934 ENOG4105P66 Membrane BZ19_2935 ENOG4105CTX dehydratase BZ19_2936 ENOG4107QZW Altronate oxidoreductase BZ19_2938 ENOG4105DPW Major facilitator superfamily MFS_1 BZ19_2941 ENOG4106W5V Membrane BZ19_2944 ENOG4105NE1 Conserved Protein BZ19_2945 ENOG41090KG Inner membrane protein YqjE BZ19_2947 ENOG4108VBZ doxx family BZ19_2948 ENOG4105CHF Glutathione S-transferase BZ19_2949 ENOG4105CWB LysR family transcriptional Regulator BZ19_295 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BZ19_2950 ENOG4108CNN domain protein BZ19_2951 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BZ19_2955 ENOG4105W4M Transport-associated protein BZ19_2957 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BZ19_2958 ENOG4105BZU Histidine kinase BZ19_296 ENOG4108ZAI phosphatidylglycerophosphatase a BZ19_2960 ENOG4105N5T Radical SAM Protein BZ19_2961 ENOG4105CBC glutamate synthase BZ19_2962 ENOG4105BZ8 glutamate synthase BZ19_2964 ENOG4105KB2 stringent starvation protein b BZ19_2965 ENOG4107MKT Stringent starvation protein a BZ19_2968 ENOG4105D6Z AFG1 family ATPase BZ19_2969 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III BZ19_2970 ENOG4105C0H protease BZ19_2971 ENOG4105C0H protease BZ19_2973 ENOG4105VFK BolA family BZ19_2974 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane BZ19_2975 ENOG4105E3I toluene tolerance BZ19_2976 ENOG4107PE3 Mammalian cell entry related domain protein BZ19_2977 ENOG4105CY3 ABC transporter, permease BZ19_2978 ENOG4105DHJ ABC, transporter BZ19_2979 ENOG4105FEU K -dependent Na -Ca exchanger BZ19_298 ENOG4105CTB Polyprenyl synthetase BZ19_2980 ENOG4105C2X Arabinose 5-phosphate isomerase BZ19_2981 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BZ19_2982 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) BZ19_2983 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BZ19_2984 ENOG4108IUZ ABC transporter BZ19_2985 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BZ19_2986 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BZ19_2987 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BZ19_2989 ENOG41080Z8 PHOSPHOCARRIER protein BZ19_2992 ENOG4105KME endoribonuclease L-psp BZ19_2994 ENOG4105D4X repressor BZ19_2995 ENOG4105C5Y PTS System BZ19_2996 ENOG4105CG3 alpha amylase, catalytic region BZ19_2997 ENOG4105NXH GreA GreB family elongation factor BZ19_2998 ENOG4108XVM Cytochrome b(562) BZ19_30 ENOG4108RNS Exports L-alanine (By similarity) BZ19_3000 ENOG4105CMS peptidase U62, modulator of DNA gyrase BZ19_3002 ENOG4105UNR (Barnase) inhibitor BZ19_3008 ENOG4105CR8 Transcriptional regulator BZ19_301 ENOG4107S0N DJ-1 family BZ19_302 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BZ19_3021 ENOG4105D1U peptidase U62 modulator of DNA gyrase BZ19_3023 ENOG4105QD6 exported protein BZ19_3024 ENOG4105C03 ribonuclease BZ19_3026 ENOG4105VQ7 Rod shape-determining protein MreD BZ19_3027 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BZ19_3028 ENOG4105DFF Rod shape-determining protein mreb BZ19_3029 ENOG41062P1 Diguanylate cyclase phosphodiesterase BZ19_3030 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family BZ19_3034 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BZ19_3035 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BZ19_3037 ENOG4105RG0 Membrane BZ19_3038 ENOG4108IA2 Sodium pantothenate symporter BZ19_304 ENOG4107RDB Major Facilitator BZ19_3040 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ19_3041 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BZ19_3044 ENOG4105CSH Transporter BZ19_3045 ENOG4108UWZ 4-Carboxymuconolactone decarboxylase BZ19_3048 ENOG4108XTF Outer Membrane Lipoprotein BZ19_3049 ENOG4105VEQ Cold shock protein BZ19_3050 ENOG4105VEQ Cold shock protein BZ19_3051 ENOG4105VEQ Cold shock protein BZ19_3055 ENOG4105CYM Glutathione S-transferase BZ19_3056 ENOG4105C2X Arabinose 5-phosphate isomerase BZ19_3057 ENOG4105EF1 ribulokinase BZ19_3059 ENOG4105CNN ABC, transporter BZ19_306 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BZ19_3060 ENOG4105C2J ABC transporter BZ19_3062 ENOG4105D1S lipid A biosynthesis BZ19_3064 ENOG4105EEQ Na H antiporter BZ19_3065 ENOG4105C7N Xanthine uracil vitamin C permease BZ19_3068 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BZ19_307 ENOG4105CCU oxidase (Subunit III) BZ19_3070 ENOG4105GVF (ABC) transporter BZ19_3072 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ19_3073 ENOG4108RVA ribokinase BZ19_3074 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BZ19_3076 ENOG4107TYG Oxidoreductase domain-containing protein BZ19_3078 ENOG4105CS6 Rhs element vgr protein BZ19_308 ENOG4105BZ9 Cytochrome C oxidase, subunit I BZ19_3080 ENOG4105CNA YD repeat protein BZ19_3082 ENOG4105CS6 Rhs element vgr protein BZ19_3087 ENOG4105CNA YD repeat protein BZ19_309 ENOG4105E2S oxidase) subunit II BZ19_3090 ENOG4105CNA YD repeat protein BZ19_3092 ENOG4105CNA YD repeat protein BZ19_3094 ENOG4105CS6 Rhs element vgr protein BZ19_310 ENOG4108NFH Sugar hydrolase BZ19_3100 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ19_311 ENOG4105EYM Major Facilitator superfamily BZ19_3110 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ19_3112 ENOG4107W52 maltose operon periplasmic protein BZ19_3115 ENOG4107FKK extracellular solute-binding protein family 1 BZ19_3116 ENOG4105D56 permease protein BZ19_3117 ENOG4105EG2 ABC transporter, permease BZ19_312 ENOG4105IEY (LipO)protein BZ19_3120 ENOG4105CFH Aspartokinase BZ19_3123 ENOG4105C3R Methionine synthase BZ19_3124 ENOG41069M3 Transcriptional regulator BZ19_3126 ENOG4108I9X Isocitrate lyase BZ19_3127 ENOG4107QP3 malate synthase g BZ19_313 ENOG4105M85 Bola protein BZ19_3140 ENOG4108Z0R Transferase BZ19_3143 ENOG4108WI1 Dna topoisomerase BZ19_3145 ENOG4105C79 DNA protecting protein DprA BZ19_3149 ENOG4105C1A potassium transporter peripheral membrane BZ19_3151 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system BZ19_3152 ENOG4105W1Y Transcriptional regulator BZ19_3155 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BZ19_3158 ENOG41067V7 50S ribosomal protein L36 BZ19_3159 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BZ19_3161 ENOG4105VPB 50S ribosomal protein L30 BZ19_3170 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BZ19_3172 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BZ19_3173 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BZ19_3175 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BZ19_318 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BZ19_3185 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BZ19_319 ENOG4105K70 DNA-binding protein BZ19_3190 ENOG4105WWK YheO domain protein BZ19_3191 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ19_3193 ENOG4108YZY peptidylprolyl cis-trans isomerase BZ19_3194 ENOG4105VKU nucleicacid-binding protein BZ19_3197 ENOG4105C5H ABC transporter BZ19_3198 ENOG4105K64 Glycosyl transferase, family 2 BZ19_320 ENOG4105EIN peptidylprolyl cis-trans isomerase BZ19_3200 ENOG4105E2B Taurine dioxygenase BZ19_3201 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BZ19_3203 ENOG4106FTQ Taurine ABC transporter, periplasmic BZ19_3205 ENOG4105DNZ Alpha Beta Hydrolase BZ19_3207 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) BZ19_3209 ENOG4108UKZ OsmC family BZ19_321 ENOG41083P1 competence protein ComEA helix-hairpin-helix repeat protein BZ19_3211 ENOG410613R integral membrane protein, YccS YhfK family BZ19_3212 ENOG4105C8Y Acetylornithine aminotransferase BZ19_3214 ENOG4105D7A ATP-binding protein BZ19_3215 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ19_3217 ENOG4105F8D glycoside hydrolase family 4 BZ19_3218 ENOG41060NJ transcriptional regulator BZ19_322 ENOG4108TGP Thioesterase superfamily protein BZ19_3221 ENOG4105DZC cytosine deaminase BZ19_3222 ENOG4107QZF nitrite reductase NADPH large subunit BZ19_3223 ENOG4105WZK nitrite reductase NADPH small subunit BZ19_3224 ENOG4107V9H nitrite transporter BZ19_3226 ENOG4105C31 Tryptophanyl-tRNA synthetase BZ19_3227 ENOG4108VXP Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity) BZ19_3228 ENOG4105DJV ribulose-phosphate 3-epimerase BZ19_3233 ENOG4105E4G Type IV pilus BZ19_3238 ENOG4108JQC penicillin-binding protein 1A BZ19_3239 ENOG4107RK2 ADP-ribose diphosphatase NudE BZ19_324 ENOG4108NFA extracellular solute-binding protein BZ19_3241 ENOG4105DQY intracellular growth attenuator BZ19_3242 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 BZ19_3243 ENOG4105VEJ Heat shock protein BZ19_3246 ENOG4105E0F Histidine kinase BZ19_3247 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ19_3248 ENOG4108RRZ Transcription elongation factor GreB BZ19_3249 ENOG4105BZM domain protein BZ19_3250 ENOG4105XFK Ferrous iron transport protein A BZ19_3253 ENOG4105RID UPF0379 protein yhcN BZ19_3255 ENOG4105MJ2 Competence protein BZ19_3257 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) BZ19_3258 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ19_326 ENOG4105C6T cysteine synthase BZ19_3262 ENOG4105E98 transcriptional regulator DeoR family BZ19_3266 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BZ19_3267 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BZ19_327 ENOG4108XM1 transcriptional regulator AsnC family BZ19_3272 ENOG4108HRK Histidine kinase BZ19_3278 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BZ19_3279 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BZ19_328 ENOG4105BZ1 (ABC) transporter BZ19_3283 ENOG4105GMB type VI secretion system effector, hcp1 family BZ19_3285 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BZ19_3286 ENOG4105C6Z Gluconate BZ19_3287 ENOG4105DIQ Transcriptional regulator BZ19_3288 ENOG4105C2I pirin domain protein BZ19_3289 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BZ19_329 ENOG4105BZ1 (ABC) transporter BZ19_3291 ENOG4105D2N Aldolase BZ19_3293 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ19_3294 ENOG4105CNN ABC, transporter BZ19_3297 ENOG4105CBX hi0933 family BZ19_3298 ENOG4105CJ3 phosphate transporter BZ19_33 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BZ19_330 ENOG4108YZA Nitrogen regulatory protein pii BZ19_3300 ENOG4108M6U Universal stress protein A BZ19_3304 ENOG4105DGW oligopeptidase A BZ19_3305 ENOG4105D6S protein involved in catabolism of external DNA BZ19_3306 ENOG4105DC8 reductase BZ19_3307 ENOG4107VHA regulatoR BZ19_3308 ENOG4107QQ0 gntp family BZ19_3309 ENOG4105BZW Glycerate kinase BZ19_331 ENOG4105BZU Histidine kinase BZ19_3313 ENOG4107H3J ribonuclease BZ19_3314 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) BZ19_3315 ENOG41066T0 asmA family BZ19_3316 ENOG4105CMB EAL domain-containing protein BZ19_3317 ENOG4105VSH 4-oxalocrotonate tautomerase BZ19_3318 ENOG4107SS6 2-dehydro-3-deoxygluconokinase BZ19_3319 ENOG4105CS0 peptidase BZ19_332 ENOG4105C29 acyl-CoA thioesterase BZ19_3323 ENOG4108PU9 oligogalacturonate-specific porin BZ19_3324 ENOG4105BZU Histidine kinase BZ19_3325 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BZ19_3326 ENOG4108JQ7 (ABC) transporter BZ19_3327 ENOG4105C3U ABC transporter BZ19_3328 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ19_3329 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ19_333 ENOG4108MNP Glycoprotein polysaccharide metabolism BZ19_3330 ENOG4105DEF Extracellular solute-binding protein, family 5 BZ19_3332 ENOG4105D5K Hemolysin activator protein BZ19_3333 ENOG4105CKT filamentous hemagglutinin BZ19_3336 ENOG4105CXY transporter BZ19_3337 ENOG4105BZU Histidine kinase BZ19_3338 ENOG4108KX4 response regulator BZ19_3339 ENOG4105DIJ Phosphoethanolamine transferase BZ19_334 ENOG41080UX Methyltransferase BZ19_3341 ENOG4105C85 amino acid BZ19_3344 ENOG4105C6T cysteine synthase BZ19_335 ENOG4105KF5 hemolysin expression-modulating protein BZ19_3350 ENOG4105CM4 permease protein BZ19_3352 ENOG4108IPW abc transporter atp-binding protein BZ19_3354 ENOG4105DFP Integrase BZ19_3356 ENOG4105T16 Transcriptional regulator (AraC family) BZ19_3357 ENOG4107RNG ABC transporter BZ19_3359 ENOG4105DFW ABC transporter BZ19_336 ENOG4108UKR Biofilm formation regulator YbaJ BZ19_3361 ENOG4105CMG Carbohydrate kinase BZ19_3363 ENOG4108TTM chaperone BZ19_3365 ENOG4106EAR Fimbrial protein BZ19_3366 ENOG4105MEV Acyl-transferase BZ19_3372 ENOG4105D13 transposase BZ19_3373 ENOG4105EM7 Selenocysteine-specific translation elongation factor BZ19_3376 ENOG4108MG3 formate dehydrogenase BZ19_3377 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BZ19_3378 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ19_3379 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ19_338 ENOG4105YK5 50S ribosomal protein L36 BZ19_3381 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BZ19_3382 ENOG4105C8Q Methyl-accepting chemotaxis BZ19_3385 ENOG4108YYI Protein of unknown function (DUF2810) BZ19_3387 ENOG4105E61 Mannitol repressor protein BZ19_3389 ENOG4105CTS PTS system mannitol-specific BZ19_3390 ENOG4106JH6 (LipO)protein BZ19_3393 ENOG4108R3E Dna-3-methyladenine glycosylase i BZ19_3395 ENOG4108ZG0 Ompa motb domain protein BZ19_3398 ENOG4107T9C Alpha amylase catalytic region BZ19_34 ENOG4105CJN penicillin-binding protein BZ19_3401 ENOG4105JKW Valine--pyruvate aminotransferase BZ19_3405 ENOG4105R2A (LipO)protein BZ19_3406 ENOG4105D99 atp gtp-binding protein BZ19_3407 ENOG4105D99 atp gtp-binding protein BZ19_3408 ENOG4105C7B Threonine dehydratase BZ19_3410 ENOG410667J hydrolase BZ19_3411 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ19_3413 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BZ19_3416 ENOG4105VG0 50S ribosomal protein l34 BZ19_3419 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BZ19_342 ENOG4105C1P efflux transporter, rnd family, mfp subunit BZ19_3422 ENOG4105C7N Xanthine uracil vitamin C permease BZ19_3423 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 BZ19_3424 ENOG4105DRP amino acid AbC transporter BZ19_3425 ENOG4105EAD ABC transporter BZ19_3426 ENOG4106PMH Extracellular solute-binding protein family 3 BZ19_343 ENOG4108IG5 Transcriptional regulator BZ19_3430 ENOG4105E2Z phosphate ABC transporter (Permease BZ19_3431 ENOG4105C8U phosphate abc transporter BZ19_3432 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BZ19_3434 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BZ19_344 ENOG41090EX DsrE family BZ19_3442 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BZ19_3444 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation BZ19_3447 ENOG4105QTB Flavodoxin BZ19_3448 ENOG4108VVK transcriptional Regulator, AsnC BZ19_345 ENOG4105EGS Mechanosensitive ion channel BZ19_3454 ENOG4108RVA ribokinase BZ19_3455 ENOG4105C0R drug resistance transporter emrb qaca subfamily BZ19_3457 ENOG4107EJG GntR family transcriptional regulator BZ19_3463 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b BZ19_3465 ENOG4105PC1 Conserved Protein BZ19_3466 ENOG4105E27 serine threonine protein kinase BZ19_3467 ENOG4108Z33 Thiol disulfide Interchange Protein BZ19_3468 ENOG4105C2M dna polymerase I BZ19_347 ENOG4105WD1 Membrane BZ19_3471 ENOG4105D4P Coproporphyrinogen iii oxidase BZ19_3472 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BZ19_3473 ENOG4105CUX Signal transduction histidine kinase BZ19_3474 ENOG4105C5F glutamine synthetase BZ19_3476 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 BZ19_3479 ENOG4105SUU thioesterase domain BZ19_3480 ENOG4105JV1 AsmA family BZ19_3481 ENOG4105C2W permease BZ19_3482 ENOG4105D6U Sodium Glutamate Symporter BZ19_3483 ENOG4105CB5 ATP-dependent DNA helicase recG BZ19_3484 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase BZ19_3485 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BZ19_3486 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BZ19_3489 ENOG4105EN6 Membrane BZ19_349 ENOG4107QMP dna polymerase iii subunits gamma and tau BZ19_3495 ENOG4105GMB type VI secretion system effector, hcp1 family BZ19_35 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BZ19_3502 ENOG4105DSJ YicC domain protein BZ19_3507 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BZ19_3510 ENOG4105W0E 50S ribosomal protein L33 BZ19_3514 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BZ19_3515 ENOG4105D16 lipopolysaccharide heptosyltransferase i BZ19_3516 ENOG4105XA0 heptosyltransferase ii BZ19_3518 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BZ19_3520 ENOG4105PXI polysaccharide deacetylase BZ19_3521 ENOG41063SB peptidase BZ19_3523 ENOG4107YZP Rhodanese domain protein BZ19_3524 ENOG4105VW4 glutaredoxin 3 BZ19_3527 ENOG4105D7W serine acetyltransferase BZ19_3528 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BZ19_3529 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BZ19_3530 ENOG4105E0F Histidine kinase BZ19_3531 ENOG4105E3W Two component transcriptional regulator (Winged helix family BZ19_3532 ENOG4105FMW periplasmic BZ19_3537 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BZ19_3539 ENOG4107QPK )-transporter BZ19_3540 ENOG4105JSC dimethylmenaquinone methyltransferase BZ19_3542 ENOG4107F9Y LysR family transcriptional regulator BZ19_3544 ENOG4105EBK exported protein BZ19_3545 ENOG4108VTS Membrane BZ19_3546 ENOG4105DP0 ferredoxin-NADP reductase BZ19_3547 ENOG4105CBT Fructose-1,6-bisphosphatase BZ19_3548 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BZ19_3549 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BZ19_3551 ENOG4108JJA ABC, transporter BZ19_3552 ENOG4108MBX Secretion Protein BZ19_3556 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BZ19_3559 ENOG41063M6 Cell Division Protein BZ19_356 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BZ19_3560 ENOG4105ETE Transcriptional regulator (LacI family BZ19_3562 ENOG4105C25 Primosomal protein n' BZ19_3564 ENOG4108Z12 YiaAB two helix domain-containing protein BZ19_3565 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) BZ19_3566 ENOG4105C28 cystathionine BZ19_3567 ENOG4105CFH Aspartokinase BZ19_3568 ENOG4105SYT Methylenetetrahydrofolate reductase BZ19_357 ENOG4105FAW cDP-glucose 4,6-dehydratase BZ19_3574 ENOG4105X58 receptor BZ19_3577 ENOG4107QZV Type I secretion membrane fusion protein BZ19_3578 ENOG4105YHG TonB family BZ19_3579 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ19_358 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ19_3580 ENOG4105EHV domain protein BZ19_3582 ENOG4105C5Q Transcriptional regulator BZ19_3585 ENOG4108Y73 Membrane BZ19_359 ENOG4108SMP Nad-dependent epimerase dehydratase BZ19_3595 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator BZ19_3596 ENOG4105C2J ABC transporter BZ19_3597 ENOG4107R9N ABC transporter BZ19_3599 ENOG41062B0 ABC transporter, permease BZ19_36 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BZ19_3600 ENOG4108WFC UPF0438 protein yifE BZ19_3601 ENOG4105C0P Mg chelatase subunit ChlI BZ19_3603 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit BZ19_3604 ENOG4105CM2 brancheD-chain amino acid aminotransferase BZ19_3606 ENOG4105C7B Threonine dehydratase BZ19_3610 ENOG4105EMY transcriptional regulator BZ19_3612 ENOG4108MA7 Inherit from COG: YD repeat protein BZ19_3614 ENOG4108VEV chaperone BZ19_3616 ENOG4105CW0 outer membrane usher protein BZ19_3617 ENOG4105GQR Chaperone BZ19_3620 ENOG4105KQ5 peptidylprolyl cis-trans isomerase BZ19_3621 ENOG4105C4R Atp-dependent dna helicase BZ19_3624 ENOG4105K63 Thioredoxin BZ19_3626 ENOG4105ESV Glycosyl transferase, family 4 BZ19_3627 ENOG4105SFE lipopolysaccharide biosynthesis protein BZ19_3628 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BZ19_3629 ENOG4108IJ1 Dehydrogenase BZ19_3630 ENOG4105C1B dTDP-glucose 4-6-dehydratase BZ19_3631 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BZ19_3632 ENOG4108WJ1 acetyltransferase BZ19_3633 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BZ19_3634 ENOG4105EGZ biosynthesis protein BZ19_3638 ENOG4105C85 amino acid BZ19_3643 ENOG410601J HemY protein BZ19_3644 ENOG4105ECF c-methyltransferase BZ19_3645 ENOG41076E6 Uroporphyrinogen-III Synthase BZ19_3647 ENOG4107T0K Adenylate cyclase BZ19_365 ENOG4108TJN glycosyl transferase group 1 BZ19_3650 ENOG4105S7Z (LipO)protein BZ19_3652 ENOG4105CT0 Protein of unknown function, DUF484 BZ19_3653 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BZ19_3654 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant BZ19_3655 ENOG4105C4R Atp-dependent dna helicase BZ19_3657 ENOG4105EQN UPF0261 protein BZ19_3659 ENOG4107QUT magnesium and cobalt transport protein CorA BZ19_366 ENOG4105C0K Gdp-mannose 4,6-dehydratase BZ19_3660 ENOG4105FR1 rard protein BZ19_3661 ENOG4108VUY thioesterase Superfamily protein BZ19_3662 ENOG4105HDD phospholipase BZ19_3663 ENOG4105C9U ATP-dependent DNA helicase RecQ BZ19_3664 ENOG4105CCF Lysine exporter protein (Lyse ygga) BZ19_3666 ENOG4108EUD Lysophospholipase BZ19_3667 ENOG4105DQF Hydrolase BZ19_3669 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BZ19_367 ENOG4105C30 Nad-dependent epimerase dehydratase BZ19_3670 ENOG4105CXY transporter BZ19_3671 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A BZ19_3673 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BZ19_3674 ENOG4108W1V Lipoprotein BZ19_3675 ENOG4105EX9 Membrane BZ19_3678 ENOG4107FS9 Membrane BZ19_368 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BZ19_3681 ENOG4105MG3 Membrane BZ19_3682 ENOG4106H78 methyltransferase BZ19_3683 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ19_3683 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BZ19_3684 ENOG4105CAK Cell division ATP-binding protein ftsE BZ19_3685 ENOG4105CRP Part of the ABC transporter FtsEX involved in BZ19_3687 ENOG4105U59 -acetyltransferase BZ19_3688 ENOG4105CP9 extracellular ligand-binding receptor BZ19_3689 ENOG4105C32 Amino acid ABC transporter (Permease) BZ19_3690 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BZ19_3691 ENOG4105C0Z ABC transporter BZ19_3692 ENOG4108IV0 ABC, transporter BZ19_3704 ENOG4107T6V glycerophosphoryl diester phosphodiesterase BZ19_3705 ENOG4105RK9 auxin efflux carrier BZ19_3706 ENOG4105DZ2 Transcriptional regulator BZ19_3707 ENOG4105EMK carboxylate amino acid amine transporter BZ19_3709 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) BZ19_371 ENOG4108QY5 Ferric enterobactin transport protein BZ19_3710 ENOG4108I5U Uridine phosphorylase BZ19_3713 ENOG4108KF1 Membrane BZ19_3714 ENOG4105CGY Dna recombination protein BZ19_3716 ENOG4105JC1 sterol-binding domain protein BZ19_3718 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BZ19_372 ENOG4107RE1 Inosine-guanosine kinase BZ19_3720 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BZ19_3722 ENOG4105D52 delta-aminolevulinic acid dehydratase BZ19_3723 ENOG4105MDZ Transcriptional activator rfaH BZ19_3725 ENOG4107QK7 reductase BZ19_3729 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BZ19_373 ENOG4105CKD glutathione-regulated potassium-efflux system protein BZ19_3730 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BZ19_3731 ENOG4108RR8 protoporphyrinogen oxidase BZ19_3738 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BZ19_374 ENOG4105EU0 Major facilitator Superfamily BZ19_3746 ENOG4105PM1 preprotein translocase subunit SecE BZ19_3747 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BZ19_375 ENOG4105CGH 5'-nucleotidase BZ19_3754 ENOG4108RS6 transposase BZ19_3755 ENOG4105D41 biosynthesis protein thiH BZ19_3758 ENOG4105D06 uba thif-type nad fad binding protein BZ19_3760 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BZ19_3766 ENOG4105R2J Conserved Protein BZ19_3768 ENOG4108T8B Protein of unknown function (DUF1481) BZ19_3769 ENOG4105C12 Phosphoribosylglycinamide synthetase BZ19_3779 ENOG41062QD Membrane BZ19_378 ENOG4108Z66 YbaK ebsC protein BZ19_3781 ENOG4105CK2 sodium dicarboxylate symporter BZ19_3782 ENOG4105WH1 Two component transcriptional regulator luxr family BZ19_3783 ENOG4105BZU Histidine kinase BZ19_379 ENOG4105MBR gumn family BZ19_3795 ENOG4108JIR Flagellum-specific ATP synthase BZ19_3799 ENOG4108HHI Type III secretion system protein BZ19_380 ENOG4105C59 p-type ATPase BZ19_3800 ENOG41083GP type iii secretion BZ19_3801 ENOG4108TN6 type iii secretion BZ19_3802 ENOG4108IUF type iii secretion BZ19_3803 ENOG41066VF YeeE YedE family protein BZ19_3804 ENOG4105KSU Redox protein BZ19_3805 ENOG4105EQ2 LysR family Transcriptional regulator BZ19_3806 ENOG4105C44 Serine transporter BZ19_3807 ENOG4105C28 cystathionine BZ19_3809 ENOG4105EHG Permease protein BZ19_381 ENOG4108Z6Z Transcriptional regulator BZ19_3810 ENOG4107R4I Periplasmic binding protein BZ19_3811 ENOG4106QJH hemin transport protein BZ19_3812 ENOG4107ENK receptor BZ19_3813 ENOG4107F3C Hemin uptake protein BZ19_3815 ENOG41090JE Utilization Protein BZ19_3816 ENOG4105D4P Coproporphyrinogen iii oxidase BZ19_382 ENOG4105G5H Membrane BZ19_3820 ENOG4105DAX Pfam:DUF2983 BZ19_383 ENOG4107QX8 SPFH domain, Band 7 family protein BZ19_3832 ENOG4108S1B Periplasmic chaperone protein BZ19_384 ENOG4107QR8 Thioredoxin BZ19_3840 ENOG41080IJ Diacylglycerol kinase BZ19_3842 ENOG4105MYN Zinc uptake regulation protein BZ19_3843 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BZ19_3844 ENOG4105P4Z Phage shock protein G BZ19_3845 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BZ19_3846 ENOG4105CDU Replicative dna helicase BZ19_3847 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BZ19_3848 ENOG4105CGF Aromatic amino acid aminotransferase BZ19_3849 ENOG4105MSB protein, conserved in bacteria BZ19_385 ENOG4105E1F short-chain dehydrogenase reductase BZ19_3850 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BZ19_3851 ENOG4108UUM single-stranded DNA-binding protein BZ19_3853 ENOG4105C0A alcohol dehydrogenase BZ19_386 ENOG4108UJV acyl-CoA thioesterase i BZ19_3866 ENOG4108SIC Transcriptional regulator BZ19_3867 ENOG4105BZ8 glutamate synthase BZ19_3868 ENOG4108RC0 Electron transport protein BZ19_3869 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BZ19_387 ENOG4108I0Y (ABC) transporter BZ19_3872 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BZ19_3877 ENOG4108ZVF (LipO)protein BZ19_3878 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BZ19_388 ENOG4105CV6 ABC transporter, permease BZ19_3880 ENOG4105KPY Small multidrug resistance protein BZ19_3881 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) BZ19_3886 ENOG4105EGS Mechanosensitive ion channel BZ19_389 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BZ19_3894 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BZ19_3895 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BZ19_3896 ENOG4105K8N protein family UPF0079, ATPase BZ19_3897 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BZ19_39 ENOG4105CNI cell division protein FtsW BZ19_390 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BZ19_3901 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BZ19_3902 ENOG4107QJR hflk protein BZ19_3903 ENOG4105EPW hflc protein BZ19_3907 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BZ19_3908 ENOG4105C2N RNA methyltransferase TrmH family group 3 BZ19_3909 ENOG4105CSU acyl-Coa dehydrogenase BZ19_3910 ENOG4105WSB biofilm stress and motility protein A BZ19_3911 ENOG4108MXZ Esterase BZ19_3913 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BZ19_3914 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BZ19_3917 ENOG4105FHY Opacity-associated protein A BZ19_3918 ENOG4108V1T peptidylprolyl cis-trans isomerase BZ19_392 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BZ19_3920 ENOG4107RNS bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic BZ19_3921 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BZ19_3922 ENOG4108UUE Transcriptional regulator BZ19_3923 ENOG41061GZ Protein of unknown function (DUF1107) BZ19_3924 ENOG4105C37 (CBS) domain BZ19_3926 ENOG4105CFU surface antigen BZ19_3927 ENOG4105MA0 exported protein BZ19_3928 ENOG4108ZHD aig2 family BZ19_3929 ENOG4105F0N pyrophosphate phospho-hydrolase BZ19_3936 ENOG4105HVQ Regulatory factor of maltose metabolism BZ19_3938 ENOG4105EAH synthase BZ19_394 ENOG4105WQ3 Rna-binding protein BZ19_3941 ENOG4105QYV Membrane BZ19_3945 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase BZ19_3946 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BZ19_3947 ENOG4105HBR Rna-binding protein BZ19_3949 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BZ19_3950 ENOG4105EEI dihydropteroate synthase BZ19_3956 ENOG4105CHV Transcription elongation factor NusA BZ19_3963 ENOG4105C1J atp-dependent rna helicase BZ19_3966 ENOG4105DEN Luciferase family BZ19_3969 ENOG4105BZS acriflavin resistance protein BZ19_3970 ENOG4105ENJ RND efflux system, outer membrane lipoprotein BZ19_3971 ENOG4106RZ4 Peptidase U32 BZ19_3972 ENOG4105CFP Peptidase U32 BZ19_3973 ENOG4105XPQ lipid carrier protein BZ19_3974 ENOG4108YYD acetyltransferase BZ19_3979 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BZ19_3980 ENOG4105DRS transport system, permease BZ19_3984 ENOG4105K4T epimerase BZ19_3985 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein BZ19_3986 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) BZ19_3987 ENOG4105FD8 phosphonate metabolism protein PhnM BZ19_3988 ENOG4105HRV phosphonate c-p lyase system protein phnl BZ19_3989 ENOG4105ENV phosphonate C-P lyase system protein PhnK BZ19_3990 ENOG4105FT8 Phosphonate metabolism BZ19_3991 ENOG4105EKV Phosphonate metabolism protein BZ19_3992 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH BZ19_3993 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG BZ19_3994 ENOG4107RJJ Transcriptional regulator BZ19_3996 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BZ19_3997 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BZ19_3998 ENOG4108JQ7 (ABC) transporter BZ19_3999 ENOG4105C3U ABC transporter BZ19_400 ENOG4108UMZ Cdp-alcohol phosphatidyltransferase BZ19_4000 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BZ19_4001 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BZ19_4003 ENOG4105XEP YhcH YjgK YiaL family protein BZ19_4005 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) BZ19_4006 ENOG4108MJ3 acetyltransferase BZ19_4008 ENOG4105MYG DNA polymerase iii, chi subunit BZ19_401 ENOG4108HPI phosphatidate Cytidylyltransferase BZ19_4010 ENOG4108M8S permease YjgP YjgQ family protein BZ19_4011 ENOG4108K5H permease YjgP YjgQ family protein BZ19_4015 ENOG4105DC6 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity) BZ19_4016 ENOG4105D85 methylase BZ19_4017 ENOG4105F6A helicase BZ19_4018 ENOG4105ECI YeeC-like protein BZ19_403 ENOG4105E8V Alpha Beta Hydrolase Fold protein BZ19_4034 ENOG4106H6R UPF0380 protein BZ19_4035 ENOG4106549 Antirestriction protein BZ19_4036 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures BZ19_4037 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles BZ19_404 ENOG41077RS Phosphatase BZ19_4042 ENOG4105DZR Type I site-specific deoxyribonuclease BZ19_4046 ENOG4108M3P Membrane BZ19_4048 ENOG4108XCZ PTS System BZ19_4049 ENOG4106R3P AraC family transcriptional regulator BZ19_4050 ENOG4108YRF PTS System BZ19_4051 ENOG4105DM4 PTS System BZ19_4052 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BZ19_4053 ENOG4105RI1 glycoprotein receptor BZ19_4060 ENOG4105DKT Transcriptional regulator BZ19_4062 ENOG4105DKP glycosyl transferase, family 9 BZ19_4065 ENOG410624X efflux transporter, rnd family, mfp subunit BZ19_4066 ENOG4105BZS acriflavin resistance protein BZ19_4069 ENOG4105BZU Histidine kinase BZ19_407 ENOG4105EQ2 LysR family Transcriptional regulator BZ19_4070 ENOG4105YBH Protein of unknown function (DUF1435) BZ19_4075 ENOG4108WPU DNA polymerase III subunit psi BZ19_4076 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BZ19_4078 ENOG4105K3G Periplasmic Protein BZ19_408 ENOG4107SET aldo keto reductase BZ19_4080 ENOG4108NRW Phospholipase, patatin family BZ19_4081 ENOG4105EYA deoxyribonuclease BZ19_4082 ENOG4105D9N nucleoside BZ19_4083 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BZ19_4087 ENOG41062Z9 Membrane BZ19_4088 ENOG4105EAC phosphoserine phosphatase BZ19_4089 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BZ19_4090 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase BZ19_4092 ENOG4105C5H ABC transporter BZ19_4093 ENOG41090EK ompa motb domain protein BZ19_4094 ENOG4108KHX Diguanylate cyclase BZ19_4097 ENOG4107SC1 transglycosylase BZ19_4099 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) BZ19_4100 ENOG4105UEI Transcriptional Regulator AraC Family BZ19_4103 ENOG4108RH0 Crea protein BZ19_4104 ENOG41065U4 response regulator BZ19_411 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BZ19_4111 ENOG4108RIR Molybdenum cofactor biosynthesis protein BZ19_4114 ENOG4106HK8 GPR1 FUN34 yaaH family protein BZ19_4118 ENOG41063Z6 transcriptional regulator, lysR family BZ19_4120 ENOG4105DTN riboflavin biosynthesis protein ribF BZ19_4123 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BZ19_4126 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BZ19_4127 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BZ19_4128 ENOG4108NIW Leucine export protein LeuE BZ19_4129 ENOG4105DWK Membrane BZ19_4131 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BZ19_4137 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BZ19_414 ENOG4105FE9 pseudouridine synthase BZ19_4140 ENOG4105D3G Pseudouridine synthase BZ19_415 ENOG4105EZE Cupin 4 family protein BZ19_4195 ENOG4105EZN Cobyrinic acid ac-diamide synthase BZ19_4196 ENOG4106JGA Chromosome (Plasmid) partitioning protein, ParB BZ19_4202 ENOG4105CMM transposase BZ19_4207 ENOG4105CMM transposase BZ19_421 ENOG4108WC9 type VI secretion system effector, hcp1 family BZ19_4211 ENOG4108C33 Resolvase BZ19_4213 ENOG4105D13 transposase BZ19_4222 ENOG4107AVE This protein is involved in the determination of copy number in gene replication. It binds to the repA promoter thus inhibiting the synthesis of the mRNA for the initiator protein repA (By similarity) BZ19_4224 ENOG4106CQM replication BZ19_4238 ENOG4105CMM transposase BZ19_4241 ENOG4105CMM transposase BZ19_425 ENOG4105HVQ Regulatory factor of maltose metabolism BZ19_426 ENOG4108JQB penicillin-binding protein 1C BZ19_427 ENOG4105DN3 alpha-2-macroglobulin domain protein BZ19_429 ENOG4105C26 Dehydrogenase BZ19_43 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BZ19_430 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BZ19_432 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BZ19_433 ENOG4105C2J ABC transporter BZ19_434 ENOG4105CNN ABC, transporter BZ19_435 ENOG4105CK5 oxidoreductase BZ19_436 ENOG4105EDK PfkB domain protein BZ19_438 ENOG4105DH8 myo-inositol catabolism BZ19_44 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BZ19_440 ENOG4108JJ7 ABC transporter BZ19_444 ENOG4108N8T regulatoR BZ19_446 ENOG4105VEQ Cold shock protein BZ19_447 ENOG4107Z6W Protein CrcB homolog BZ19_448 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) BZ19_45 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BZ19_452 ENOG4105DZ1 carboxypeptidase BZ19_453 ENOG4105K6T rare lipoprotein A BZ19_454 ENOG4105CNI cell division protein FtsW BZ19_455 ENOG4105CJN penicillin-binding protein BZ19_457 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BZ19_458 ENOG4108I1J Integrase BZ19_471 ENOG4105E4C Lytic transglycosylase catalytic BZ19_484 ENOG4105DJF DNA polymerase III, delta' subunit BZ19_487 ENOG4107PAI alpha helical protein BZ19_488 ENOG4105CDA abc transporter atp-binding protein BZ19_489 ENOG4105DRP amino acid AbC transporter BZ19_490 ENOG4105EAD ABC transporter BZ19_491 ENOG4107RP9 extracellular solute-binding protein, family 3 BZ19_492 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BZ19_493 ENOG4108JU5 Magnesium and cobalt efflux protein BZ19_495 ENOG4105C9A Phoh family BZ19_497 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BZ19_50 ENOG4105M6F mutator MutT protein BZ19_504 ENOG4105CAQ asparagine synthetase BZ19_505 ENOG4105D4U had-superfamily hydrolase, subfamily iia BZ19_506 ENOG4105E2R ROK family BZ19_507 ENOG4105CE4 GlcNAc 6-P deacetylase BZ19_509 ENOG4105CI1 PTS System BZ19_513 ENOG41090R7 Ferric uptake BZ19_514 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) BZ19_515 ENOG4105NNH LexA regulated protein BZ19_517 ENOG4105EV9 Alpha Beta Hydrolase BZ19_520 ENOG4105DFP Integrase BZ19_522 ENOG4108Z1B Cyclase dehydrase BZ19_524 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BZ19_525 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BZ19_526 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BZ19_528 ENOG4105BZN citrate synthase BZ19_529 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BZ19_53 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BZ19_530 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BZ19_532 ENOG4105E33 succinate dehydrogenase BZ19_533 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BZ19_534 ENOG4105C7S Dehydrogenase BZ19_536 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BZ19_537 ENOG4108RS6 transposase BZ19_538 ENOG4105C4M (Ubiquinol oxidase) subunit I BZ19_539 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BZ19_541 ENOG4105KJB cyd operon protein YbgE BZ19_542 ENOG4107YD3 Thioesterase BZ19_543 ENOG4105E02 MotA TolQ exbB proton channel BZ19_544 ENOG4105M8F Biopolymer transport protein exbD tolR BZ19_545 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ19_545 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BZ19_547 ENOG4105KCK Peptidoglycan-associated lipoprotein BZ19_548 ENOG4105UFD tol-pal system protein YbgF BZ19_55 ENOG4105D7Q type ii secretion system BZ19_558 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BZ19_559 ENOG4105PGM cation diffusion facilitator family transporter BZ19_56 ENOG4107QHF type ii secretion system protein e BZ19_561 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BZ19_564 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BZ19_566 ENOG4105F0Z galactose-1-phosphate uridylyltransferase BZ19_567 ENOG4105CMR udp-glucose 4-epimerase BZ19_57 ENOG4108ZUW Major pilin subunit BZ19_570 ENOG4105DKW ABC transporter BZ19_571 ENOG4105F4R Transcriptional regulator mode BZ19_572 ENOG410680R Protein of unknown function (DUF2592) BZ19_573 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BZ19_574 ENOG4105E0C molybdate abc transporter BZ19_576 ENOG4108K4B hydrolase BZ19_58 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BZ19_581 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BZ19_582 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BZ19_583 ENOG4108JEI Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity) BZ19_585 ENOG4105VYA Uncharacterized conserved protein (DUF2132) BZ19_586 ENOG4105CHW UPF0052 protein BZ19_588 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BZ19_59 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BZ19_590 ENOG4105M00 molybdopterin converting factor, subunit 1 BZ19_591 ENOG4108ZAF Molybdopterin BZ19_592 ENOG4105HFZ Membrane BZ19_596 ENOG4105C94 Transporter BZ19_597 ENOG4105CN8 Transcriptional regulator BZ19_599 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BZ19_60 ENOG4106A72 regulatory protein AmpE BZ19_600 ENOG4105EAA nucleoside BZ19_602 ENOG4105BZU Histidine kinase BZ19_607 ENOG4107QWP ABC-2 type transporter BZ19_608 ENOG4107QWP ABC-2 type transporter BZ19_609 ENOG4105CJ1 ABC, transporter BZ19_61 ENOG4105C85 amino acid BZ19_611 ENOG4107MVR Transcriptional regulator BZ19_612 ENOG4105C1J atp-dependent rna helicase BZ19_614 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BZ19_616 ENOG41061WM D-Alanyl-D-Alanine BZ19_617 ENOG4105CXG d-lactate dehydrogenase BZ19_619 ENOG4105N1F Hnh endonuclease BZ19_62 ENOG41073TP transcriptional regulator BZ19_621 ENOG4105Y3U Transglycosylase-associated protein BZ19_623 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein BZ19_626 ENOG4108W15 Protein of unknown function (DUF1456) BZ19_628 ENOG4105C32 Amino acid ABC transporter (Permease) BZ19_629 ENOG4105CNN ABC, transporter BZ19_63 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BZ19_630 ENOG4108JJB ABC transporter BZ19_631 ENOG4108IV0 ABC, transporter BZ19_634 ENOG4105KHC sulfurtransferase BZ19_635 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BZ19_636 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component BZ19_637 ENOG4108IJ8 ABC transporter BZ19_638 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component BZ19_639 ENOG4105D5Q Arginine ornithine antiporter BZ19_64 ENOG4107QSN dihydrolipoamide acetyltransferase BZ19_640 ENOG4105CXN decarboxylase BZ19_642 ENOG4105FDR Membrane BZ19_644 ENOG4105DVT helicase BZ19_645 ENOG4105CH6 catalase BZ19_646 ENOG4108UII YfaZ family BZ19_647 ENOG4105E0U tyrosine-specific transport protein BZ19_65 ENOG4107QN2 dihydrolipoyl dehydrogenase BZ19_650 ENOG4105XPH Ferredoxin BZ19_651 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ19_652 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BZ19_654 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BZ19_655 ENOG4105BZU Histidine kinase BZ19_656 ENOG41068CG regulatoR BZ19_657 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC BZ19_658 ENOG4106UW1 Major Facilitator superfamily BZ19_66 ENOG4107QIJ Aconitate hydratase 2 BZ19_660 ENOG4105FCK Membrane BZ19_665 ENOG4107R6D beta-lactam binding protein AmpH BZ19_666 ENOG4105CT4 transporter BZ19_668 ENOG4105C8Q Methyl-accepting chemotaxis BZ19_672 ENOG4105Y50 Virulence Protein BZ19_674 ENOG4105HRS Antitermination protein BZ19_675 ENOG4105G63 Type III effector Hrp-dependent BZ19_677 ENOG4105MVE transcriptional regulator BZ19_678 ENOG4105QG4 Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity) BZ19_68 ENOG4105RPH Inner membrane protein YddG BZ19_682 ENOG4105TKZ Tail Sheath BZ19_690 ENOG4108T86 baseplate J family protein BZ19_694 ENOG4108Q3X Transcriptional regulator BZ19_696 ENOG4105CS2 ec 3.2.1.21 BZ19_700 ENOG4105GMB type VI secretion system effector, hcp1 family BZ19_703 ENOG4105E68 Sulfatase BZ19_704 ENOG4105PAN UPF0352 protein BZ19_707 ENOG4105CFI type iii restriction protein res subunit BZ19_708 ENOG4105I08 Pseudouridine synthase BZ19_709 ENOG4105C2C drug resistance transporter, Bcr CflA BZ19_71 ENOG4108ZRK uncharacterized protein yacC BZ19_710 ENOG4105HG6 BZ19_711 ENOG4108JQ5 ABC transporter BZ19_712 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BZ19_713 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BZ19_714 ENOG4105E43 Extracellular solute-binding protein, family 5 BZ19_715 ENOG4105CXC rtn protein BZ19_716 ENOG4107TT5 NLP P60 protein BZ19_717 ENOG41076MN Phosphoesterase, PA-phosphatase related BZ19_718 ENOG4105CKI cobalamin synthesis protein BZ19_72 ENOG4105E3B Multicopper oxidase BZ19_720 ENOG4107YCY Transcriptional regulator BZ19_721 ENOG4105DEI Mannitol dehydrogenase BZ19_725 ENOG4105KRS Proteinase inhibitor BZ19_726 ENOG4105CHR reductase BZ19_729 ENOG4105C26 Dehydrogenase BZ19_73 ENOG4108UGV hypoxanthine phosphoribosyltransferase BZ19_731 ENOG4105E66 phosphoriboisomerase A BZ19_733 ENOG4105C2J ABC transporter BZ19_734 ENOG41071MT Part of the ABC transporter complex LsrABCD involved in autoinducer 2 (AI-2) import. Probably responsible for the translocation of the substrate across the membrane BZ19_736 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein BZ19_737 ENOG4105DE4 1-phosphofructokinase BZ19_738 ENOG4105DM4 PTS System BZ19_739 ENOG4108SGD regulatory protein BZ19_74 ENOG41077A9 carbonic anhydrase BZ19_742 ENOG4108UIF Chaperone BZ19_743 ENOG4108D1K outer membrane usher protein BZ19_745 ENOG4105HMI Membrane BZ19_746 ENOG4105DUM transcriptional regulator, lysR family BZ19_748 ENOG4108IQI permease BZ19_75 ENOG4105DA5 (ABC) transporter BZ19_750 ENOG4105EHG Permease protein BZ19_752 ENOG4105D05 Receptor BZ19_753 ENOG4108TGY Glutathione S-transferase BZ19_756 ENOG4105D01 (LipO)protein BZ19_758 ENOG4108UMI ABC transporter, permease BZ19_759 ENOG4105DZ1 carboxypeptidase BZ19_76 ENOG4105E3A (ABC) transporter BZ19_760 ENOG4105C44 Serine transporter BZ19_761 ENOG4107FB0 transcriptional regulator DeoR family BZ19_763 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BZ19_765 ENOG4105D0C transport protein BZ19_766 ENOG41090BQ Glutaredoxin BZ19_767 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress BZ19_768 ENOG4108RMJ sensory transduction regulator BZ19_769 ENOG4107RUE extracellular solute-binding protein family 1 BZ19_77 ENOG4107BJW polysaccharide deacetylase BZ19_770 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BZ19_771 ENOG4105F38 ABC transporter, permease BZ19_772 ENOG4105D38 putrescine abc transporter BZ19_773 ENOG4105RBQ inner membrane protein ybjO BZ19_775 ENOG4106TNF Periplasmic binding protein BZ19_778 ENOG4108I9K permease protein BZ19_779 ENOG4105E0A ABC, transporter BZ19_780 ENOG410642S Nicotianamine synthase protein BZ19_781 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) BZ19_782 ENOG4108I0N Transporter, RarD family, DMT superfamily protein BZ19_783 ENOG4105DMR ABC, transporter BZ19_784 ENOG4105GBT ABC transporter BZ19_785 ENOG4106PMH Extracellular solute-binding protein family 3 BZ19_786 ENOG4105E5Z arginine transporter ATP-binding subunit BZ19_787 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) BZ19_788 ENOG41064MM (LipO)protein BZ19_789 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BZ19_790 ENOG4105CGD Nad-dependent epimerase dehydratase BZ19_791 ENOG4105C5W Aldolase BZ19_792 ENOG4105C7K acetolactate synthase BZ19_793 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BZ19_795 ENOG4105DWU Membrane BZ19_796 ENOG4105CPB ATP-dependent endonuclease of the OLD family BZ19_797 ENOG4108MJ5 VirK protein BZ19_798 ENOG4105DJY efflux transporter, rnd family, mfp subunit BZ19_800 ENOG4105VEQ Cold shock protein BZ19_802 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ19_803 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BZ19_805 ENOG4108JJ8 (ABC) transporter BZ19_806 ENOG4108JJ9 ABC, transporter BZ19_807 ENOG4105C3M thioredoxin reductase BZ19_808 ENOG4105EW9 transcriptional regulator AsnC family BZ19_809 ENOG4105CNU cell division protein FtsK BZ19_81 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BZ19_812 ENOG4105D1H recombination factor protein RarA BZ19_814 ENOG4108ISG Major Facilitator BZ19_815 ENOG4105F1A Pyruvate formate-lyase BZ19_817 ENOG4105C6N Formate acetyltransferase BZ19_818 ENOG4105TMB Formate nitrite transporter BZ19_819 ENOG4105DDY UPF0142 protein ycaO BZ19_82 ENOG4105DJ0 Poly(A) Polymerase BZ19_820 ENOG4105HDK L-asparaginase BZ19_826 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BZ19_829 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BZ19_832 ENOG4105E32 cytoplasmic protein BZ19_833 ENOG4105VEQ Cold shock protein BZ19_834 ENOG4105W49 UPF0434 protein BZ19_836 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups BZ19_837 ENOG4106371 Methyltransferase BZ19_838 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) BZ19_839 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) BZ19_84 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BZ19_841 ENOG4105DIT ErfK YbiS YcfS YnhG family protein BZ19_842 ENOG4105EAQ (twin-arginine translocation) pathway signal BZ19_843 ENOG4105C5X domain protein BZ19_844 ENOG4105CGF Aromatic amino acid aminotransferase BZ19_848 ENOG4105CD8 aminopeptidase N BZ19_850 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) BZ19_851 ENOG4105QVC MOSC domain-containing protein BZ19_853 ENOG4105C5H ABC transporter BZ19_854 ENOG4105F1S paraquat-inducible protein a BZ19_855 ENOG4105DY2 Paraquat-inducible protein b BZ19_856 ENOG4108Q2G (LipO)protein BZ19_857 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ19_86 ENOG4107XID 2'-5' rna ligase BZ19_860 ENOG4105DAN ATP-dependent protease BZ19_862 ENOG4108RS6 transposase BZ19_863 ENOG4105UYK outer membrane protein a BZ19_865 ENOG4108RZ1 DNA transformation protein BZ19_866 ENOG4105EM2 membrane BZ19_867 ENOG410901E Membrane BZ19_868 ENOG41088T4 Helicase IV BZ19_87 ENOG4105CQ7 ATP-dependent helicase BZ19_870 ENOG4108Q67 UPF0319 protein BZ19_871 ENOG4105K4P CoA-binding domain protein BZ19_88 ENOG4105BZ4 penicillin-binding protein BZ19_89 ENOG4105E0A ABC, transporter BZ19_897 ENOG4108Z0T Part of a sulfur-relay system (By similarity) BZ19_90 ENOG4105J76 Periplasmic binding protein BZ19_900 ENOG4108BUD transposase BZ19_908 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BZ19_909 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BZ19_91 ENOG4105S6R Iron-hydroxamate transporter permease subunit BZ19_910 ENOG4105CHR reductase BZ19_911 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BZ19_913 ENOG4108KQ6 Enoyl-CoA hydratase BZ19_914 ENOG4105CHR reductase BZ19_916 ENOG41062T2 Acyl carrier protein BZ19_917 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BZ19_922 ENOG4105CDV Ompa motb domain protein BZ19_924 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BZ19_945 ENOG4105C5H ABC transporter BZ19_947 ENOG4105D06 uba thif-type nad fad binding protein BZ19_948 ENOG4105CVM Molybdenum cofactor synthesis domain protein BZ19_95 ENOG4105EN6 Membrane BZ19_950 ENOG4105C19 ABC transporter BZ19_951 ENOG4105ENT Efflux transporter rnd family, mfp subunit BZ19_956 ENOG4105EGI Transcriptional regulator BZ19_957 ENOG4105CBP Major Facilitator BZ19_959 ENOG4105DHF Membrane BZ19_962 ENOG4108HWV )-transporter BZ19_963 ENOG4107GZ4 SanA protein BZ19_966 ENOG41067MG lrgb family BZ19_968 ENOG4105E5W Transporter BZ19_973 ENOG4105D1F ATP-binding protein BZ19_976 ENOG4108GAE asmA family BZ19_977 ENOG4105EE5 Membrane protein terC BZ19_978 ENOG4108819 ferric iron reductase BZ19_979 ENOG4105DY8 decarboxylase BZ19_980 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BZ19_982 ENOG4105DUU IucA IucC family protein BZ19_983 ENOG4105E0A ABC, transporter BZ19_984 ENOG4105TVJ transport system, permease BZ19_985 ENOG4105DQ5 transport system permease protein BZ19_986 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BZ19_987 ENOG4105CNM Receptor BZ19_988 ENOG4105DUU IucA IucC family protein BZ19_989 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ19_99 ENOG4105C0H protease BZ19_990 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BZ19_991 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BZ19_992 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BZ19_995 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BZ19_998 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)