locus-tag	class	description
LGL92_00010	COG0592	DNA-directed DNA polymerase activity
LGL92_00020	COG0187	DNA topoisomerase II activity
LGL92_00025	COG0561	phosphatase activity
LGL92_00030	COG0823	Involved in the tonB-independent uptake of proteins
LGL92_00035	COG5645	(Lipo)protein
LGL92_00050	COG0569	domain protein
LGL92_00050	COG2985	domain, Protein
LGL92_00055	COG3977	Valine--pyruvate aminotransferase
LGL92_00060	COG2885	chlorophyll binding
LGL92_00080	COG2818	Glycosylase
LGL92_00130	COG2213	PTS system mannitol-specific
LGL92_00130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL92_00140	COG3722	fumarate hydratase activity
LGL92_00150	COG2258	MOSC domain
LGL92_00155	COG0840	transmembrane signaling receptor activity
LGL92_00160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL92_00175	COG0437	4 iron, 4 sulfur cluster binding
LGL92_00180	COG2864	formate dehydrogenase
LGL92_00190	COG1921	L-seryl-tRNASec selenium transferase activity
LGL92_00195	COG3276	selenocysteine insertion sequence binding
LGL92_00200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LGL92_00210	COG3274	enterobacterial common antigen metabolic process
LGL92_00250	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGL92_00255	COG2986	histidine ammonia-lyase
LGL92_00275	COG2194	sulfuric ester hydrolase activity
LGL92_00280	COG2197	response regulator
LGL92_00285	COG3851	Histidine kinase
LGL92_00290	COG2271	Major facilitator Superfamily
LGL92_00300	COG0747	negative chemotaxis
LGL92_00305	COG0601	transmembrane transport
LGL92_00310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL92_00315	COG0444	Belongs to the ABC transporter superfamily
LGL92_00320	COG4608	Belongs to the ABC transporter superfamily
LGL92_00325	COG2194	sulfuric ester hydrolase activity
LGL92_00355	COG1215	transferase activity, transferring glycosyl groups
LGL92_00360	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGL92_00365	COG0457	Tetratricopeptide repeat
LGL92_00365	COG3118	belongs to the thioredoxin family
LGL92_00370	COG2199	diguanylate cyclase activity
LGL92_00370	COG2200	EAL domain
LGL92_00375	COG1301	dicarboxylic acid transport
LGL92_00380	COG0612	Peptidase, M16
LGL92_00385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL92_00390	COG1942	4-Oxalocrotonate Tautomerase
LGL92_00395	COG2200	EAL domain
LGL92_00400	COG2134	cdp-diacylglycerol pyrophosphatase
LGL92_00405	COG1295	ribonuclease BN
LGL92_00415	COG1301	dicarboxylic acid transport
LGL92_00420	COG0626	cystathionine gamma-synthase activity
LGL92_00435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL92_00440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGL92_00445	COG0339	signal peptide processing
LGL92_00450	COG0742	ribosomal rna small subunit methyltransferase
LGL92_00460	COG0589	response to stress
LGL92_00470	COG0306	phosphate transporter
LGL92_00475	COG2081	HI0933 family
LGL92_00525	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL92_00650	COG1247	-acetyltransferase
LGL92_00660	COG1741	Belongs to the pirin family
LGL92_00665	COG1609	Transcriptional regulator
LGL92_00675	COG3265	gluconokinase activity
LGL92_00680	COG2095	MarC family integral membrane protein
LGL92_00685	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL92_00690	COG3275	phosphorelay sensor kinase activity
LGL92_00695	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGL92_00700	COG1523	belongs to the glycosyl hydrolase 13 family
LGL92_00705	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGL92_00710	COG0297	glycogen (starch) synthase activity
LGL92_00715	COG0058	SHG alpha-glucan phosphorylase activity
LGL92_00720	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL92_00725	COG1349	DNA-binding transcription factor activity
LGL92_00730	COG0705	Rhomboid family
LGL92_00740	COG2909	trisaccharide binding
LGL92_00745	COG0058	SHG alpha-glucan phosphorylase activity
LGL92_00750	COG1640	4-alpha-glucanotransferase
LGL92_00760	COG1040	competence protein
LGL92_00765	COG0596	Alpha beta hydrolase
LGL92_00785	COG1918	ferrous iron import across plasma membrane
LGL92_00790	COG2183	response to ionizing radiation
LGL92_00815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL92_00830	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGL92_00840	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGL92_00845	COG1011	Hydrolase
LGL92_00855	COG0494	nUDIX hydrolase
LGL92_00860	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL92_00885	COG4796	Type ii and iii secretion system protein
LGL92_00890	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL92_00910	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGL92_00920	COG0180	Tryptophanyl-tRNA synthetase
LGL92_00940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGL92_00945	COG0402	S-adenosylhomocysteine deaminase activity
LGL92_00950	COG0738	Major facilitator superfamily
LGL92_00965	COG1609	Transcriptional regulator
LGL92_00970	COG1486	melibiose metabolic process
LGL92_00975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL92_00990	COG1289	transmembrane transporter activity
LGL92_00995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL92_01000	COG1765	OsmC-like protein
LGL92_01025	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL92_01030	COG3954	Phosphoribulokinase
LGL92_01040	COG0429	hydrolase of the alpha beta-hydrolase fold
LGL92_01050	COG0859	PFAM glycosyl transferase family 9
LGL92_01055	COG1216	Glycosyl transferase, family 2
LGL92_01060	COG0488	(ABC) transporter
LGL92_01065	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL92_01075	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGL92_01080	COG1047	Peptidyl-prolyl cis-trans
LGL92_01090	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL92_01095	COG2964	Protein conserved in bacteria
LGL92_01105	COG2923	Belongs to the DsrF TusC family
LGL92_01110	COG2168	tRNA wobble position uridine thiolation
LGL92_01115	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGL92_01120	COG0049	tRNA binding
LGL92_01130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGL92_01145	COG0051	transcription antitermination factor activity, RNA binding
LGL92_01150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGL92_01160	COG0089	rRNA binding
LGL92_01165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGL92_01170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGL92_01175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGL92_01185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGL92_01190	COG0255	Belongs to the universal ribosomal protein uL29 family
LGL92_01195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGL92_01200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGL92_01210	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGL92_01235	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGL92_01240	COG1841	ribosomal large subunit assembly
LGL92_01245	COG0200	Binds to the 23S rRNA
LGL92_01250	COG0201	protein transport
LGL92_01255	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL92_01260	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGL92_01270	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGL92_01280	COG0203	ribosomal protein L17
LGL92_01285	COG0789	Transcriptional regulator
LGL92_01290	COG3036	rescue of stalled ribosome
LGL92_01295	COG1970	mechanosensitive ion channel activity
LGL92_01305	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGL92_01305	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGL92_01310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGL92_01315	COG0242	peptide deformylase activity
LGL92_01320	COG0758	DNA mediated transformation
LGL92_01325	COG2922	Belongs to the Smg family
LGL92_01330	COG0551	DNA topoisomerase type I activity
LGL92_01335	COG0009	L-threonylcarbamoyladenylate synthase
LGL92_01345	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGL92_01375	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL92_01380	COG3162	membrane
LGL92_01385	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGL92_01390	COG1301	dicarboxylic acid transport
LGL92_01395	COG2391	methyltransferase activity
LGL92_01400	COG0425	Belongs to the sulfur carrier protein TusA family
LGL92_01410	COG1086	Polysaccharide biosynthesis protein
LGL92_01415	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL92_01420	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL92_01425	COG2089	acid synthase
LGL92_01445	COG2755	lipolytic protein G-D-S-L family
LGL92_01445	COG1083	cytidylyl-transferase
LGL92_01450	COG1028	Short-chain dehydrogenase reductase Sdr
LGL92_01470	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL92_01470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL92_01475	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LGL92_01495	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL92_01570	COG3596	GTP binding
LGL92_01625	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LGL92_01650	COG0582	viral genome integration into host DNA
LGL92_01660	COG1309	transcriptional regulator
LGL92_01665	COG4232	protein-disulfide reductase activity
LGL92_01675	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL92_01705	COG1509	lysine 2,3-aminomutase activity
LGL92_01715	COG3397	chitin binding
LGL92_01735	COG3188	usher protein
LGL92_01755	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL92_01760	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL92_01765	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL92_01770	COG1053	succinate dehydrogenase
LGL92_01775	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGL92_01780	COG3264	Mechanosensitive ion channel
LGL92_01780	COG1511	domain protein
LGL92_01785	COG0688	phosphatidylethanolamine metabolic process
LGL92_01790	COG1162	GTPase activity
LGL92_01795	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGL92_01815	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGL92_01820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGL92_01820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGL92_01825	COG0802	atpase or kinase
LGL92_01830	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL92_01840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGL92_01850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGL92_01855	COG0330	HflC and HflK could
LGL92_01860	COG0330	HflC and HflK could
LGL92_01865	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LGL92_01870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGL92_01875	COG1959	2 iron, 2 sulfur cluster binding
LGL92_01880	COG0557	exoribonuclease II activity
LGL92_01885	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL92_01905	COG3121	Chaperone
LGL92_01910	COG3188	usher protein
LGL92_01930	COG1073	alpha beta
LGL92_01940	COG0360	Binds together with S18 to 16S ribosomal RNA
LGL92_01945	COG2965	DNA replication, synthesis of RNA primer
LGL92_01950	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGL92_01955	COG0359	binds to the 23S rRNA
LGL92_01960	COG3061	Opacity-associated protein A
LGL92_01965	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL92_01975	COG0737	Belongs to the 5'-nucleotidase family
LGL92_01985	COG1218	3'(2'),5'-bisphosphate nucleotidase
LGL92_01990	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LGL92_02000	COG1253	flavin adenine dinucleotide binding
LGL92_02005	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL92_02010	COG0729	surface antigen
LGL92_02015	COG2911	Protein conserved in bacteria
LGL92_02020	COG2105	PFAM AIG2 family protein
LGL92_02025	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGL92_02035	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL92_02050	COG3423	Transcriptional regulator
LGL92_02065	COG0142	geranyltranstransferase activity
LGL92_02080	COG0697	spore germination
LGL92_02085	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGL92_02090	COG0642	Histidine kinase
LGL92_02095	COG0745	RESPONSE REGULATOR receiver
LGL92_02100	COG2027	D-alanyl-D-alanine carboxypeptidase
LGL92_02110	COG1534	Rna-binding protein
LGL92_02115	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LGL92_02125	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGL92_02130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGL92_02135	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGL92_02155	COG0195	Participates in both transcription termination and antitermination
LGL92_02165	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGL92_02180	COG1185	polyribonucleotide nucleotidyltransferase activity
LGL92_02195	COG0513	Belongs to the DEAD box helicase family
LGL92_02200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGL92_02205	COG0814	amino acid
LGL92_02215	COG0826	peptidase U32
LGL92_02220	COG0826	peptidase U32
LGL92_02225	COG3154	lipid carrier protein
LGL92_02230	COG3153	acetyltransferase
LGL92_02235	COG2827	Endonuclease containing a URI domain
LGL92_02240	COG0531	amino acid
LGL92_02245	COG1982	Orn Lys Arg decarboxylase major
LGL92_02255	COG3787	Belongs to the UPF0306 family
LGL92_02260	COG0702	epimerase
LGL92_02265	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGL92_02270	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LGL92_02275	COG3454	Phosphonate metabolism
LGL92_02280	COG4778	phosphonate C-P lyase system protein PhnL
LGL92_02285	COG4107	phosphonate C-P lyase system protein PhnK
LGL92_02290	COG3627	carbon phosphorus lyase activity
LGL92_02295	COG3626	phosphonate metabolism
LGL92_02300	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LGL92_02305	COG3624	Phosphonate C-P lyase system protein PhnG
LGL92_02325	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LGL92_02340	COG2927	DNA polymerase III (CHI subunit)
LGL92_02345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGL92_02350	COG0795	lipopolysaccharide-transporting ATPase activity
LGL92_02355	COG0795	lipopolysaccharide-transporting ATPase activity
LGL92_02405	COG5492	domain, Protein
LGL92_02425	COG3119	arylsulfatase activity
LGL92_02430	COG1349	DNA-binding transcription factor activity
LGL92_02440	COG2222	sugar isomerase
LGL92_02445	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL92_02450	COG3715	PTS system
LGL92_02455	COG3716	PTS system mannose fructose sorbose family IID component
LGL92_02465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL92_02475	COG1028	Short-chain dehydrogenase reductase Sdr
LGL92_02485	COG0641	radical SAM
LGL92_02490	COG3119	arylsulfatase activity
LGL92_02515	COG0859	PFAM glycosyl transferase family 9
LGL92_02530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL92_02535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL92_02545	COG2376	Dihydroxyacetone kinase
LGL92_02550	COG1461	Dihydroxyacetone kinase
LGL92_02555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL92_02555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL92_02555	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LGL92_02595	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LGL92_02610	COG2823	Periplasmic or secreted lipoprotein
LGL92_02620	COG4667	esterase of the alpha-beta hydrolase superfamily
LGL92_02625	COG0084	hydrolase, TatD family'
LGL92_02630	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL92_02645	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGL92_02655	COG3726	membrane protein affecting hemolysin expression
LGL92_02660	COG0560	Phosphoserine phosphatase
LGL92_02675	COG0488	(ABC) transporter
LGL92_02695	COG0741	lytic transglycosylase activity
LGL92_02700	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LGL92_02705	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGL92_02710	COG0406	alpha-ribazole phosphatase activity
LGL92_02715	COG3708	Transcriptional regulator
LGL92_02715	COG2207	Transcriptional regulator
LGL92_02720	COG3045	CreA protein
LGL92_02725	COG0745	RESPONSE REGULATOR receiver
LGL92_02760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL92_02765	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGL92_02770	COG0477	Major facilitator Superfamily
LGL92_02780	COG1584	GPR1 FUN34 yaaH family protein
LGL92_02785	COG0443	Heat shock 70 kDa protein
LGL92_02795	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL92_02800	COG0583	DNA-binding transcription factor activity
LGL92_02810	COG0196	riboflavin kinase activity
LGL92_02820	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGL92_02825	COG1047	Peptidyl-prolyl cis-trans
LGL92_02830	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGL92_02845	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGL92_02855	COG2966	Psort location CytoplasmicMembrane, score
LGL92_02880	COG2967	ApaG domain
LGL92_02885	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGL92_02890	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LGL92_02900	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LGL92_02910	COG0564	pseudouridine synthase activity
LGL92_02915	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGL92_02920	COG0417	DNA replication proofreading
LGL92_02925	COG0586	Pfam SNARE associated Golgi protein
LGL92_02935	COG1178	ABC-type Fe3 transport system permease component
LGL92_02940	COG4143	(ABC) transporter
LGL92_02955	COG2814	Major facilitator Superfamily
LGL92_02965	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL92_02970	COG0473	3-isopropylmalate dehydrogenase activity
LGL92_02985	COG1022	Amp-dependent synthetase and ligase
LGL92_02990	COG0028	Belongs to the TPP enzyme family
LGL92_03010	COG0675	Transposase, IS605 OrfB family
LGL92_03025	COG0275	rRNA processing
LGL92_03030	COG3116	cell division
LGL92_03035	COG0768	penicillin binding
LGL92_03040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGL92_03045	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGL92_03060	COG0772	Belongs to the SEDS family
LGL92_03065	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGL92_03070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL92_03085	COG0849	cell division
LGL92_03090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGL92_03115	COG0494	nUDIX hydrolase
LGL92_03135	COG0516	GMP reductase activity
LGL92_03140	COG1459	type II secretion system
LGL92_03145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL92_03150	COG4969	Belongs to the N-Me-Phe pilin family
LGL92_03165	COG3725	Membrane protein required for beta-lactamase induction
LGL92_03170	COG1113	amino acid transport
LGL92_03175	COG2186	Transcriptional regulator
LGL92_03180	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LGL92_03185	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL92_03190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL92_03200	COG1049	propionate catabolic process, 2-methylcitrate cycle
LGL92_03205	COG3112	Uncharacterised protein family (UPF0231)
LGL92_03220	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGL92_03230	COG2132	Multicopper oxidase
LGL92_03240	COG0288	reversible hydration of carbon dioxide
LGL92_03245	COG1131	(ABC) transporter
LGL92_03250	COG0842	Transport permease protein
LGL92_03255	COG0726	polysaccharide deacetylase
LGL92_03260	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGL92_03265	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGL92_03270	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGL92_03275	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGL92_03280	COG0617	tRNA 3'-terminal CCA addition
LGL92_03295	COG1489	DNA binding
LGL92_03300	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGL92_03305	COG1643	Atp-dependent helicase
LGL92_03310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL92_03315	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGL92_03325	COG0316	Belongs to the HesB IscA family
LGL92_03330	COG2860	membrane
LGL92_03340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL92_03345	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL92_03350	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL92_03360	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL92_03365	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL92_03370	COG3956	TIGRFAM MazG family protein
LGL92_03375	COG0504	CTP synthase activity
LGL92_03385	COG0602	queuosine metabolic process
LGL92_03390	COG0720	synthase
LGL92_03395	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGL92_03405	COG0175	sulfate reduction
LGL92_03420	COG2234	aminopeptidase activity
LGL92_03425	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGL92_03425	COG1648	precorrin-2 dehydrogenase activity
LGL92_03430	COG0175	sulfate reduction
LGL92_03435	COG2895	sulfate adenylyltransferase (ATP) activity
LGL92_03440	COG0529	Catalyzes the synthesis of activated sulfate
LGL92_03450	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGL92_03460	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGL92_03465	COG0585	pseudouridine synthase activity
LGL92_03470	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGL92_03480	COG1388	LysM domain
LGL92_03480	COG4942	peptidase
LGL92_03485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGL92_03490	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGL92_03565	COG2205	protein histidine kinase activity
LGL92_03565	COG0784	Response regulator, receiver
LGL92_03590	COG0741	lytic transglycosylase activity
LGL92_03725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL92_03755	COG3397	chitin binding
LGL92_03765	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGL92_03810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL92_03820	COG3031	protein transport across the cell outer membrane
LGL92_03845	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL92_03845	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL92_03860	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGL92_03865	COG2137	regulation of response to DNA damage stimulus
LGL92_03870	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGL92_03875	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGL92_03910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL92_03915	COG1238	metal cluster binding
LGL92_03920	COG2918	glutathione biosynthetic process
LGL92_03925	COG1854	S-ribosylhomocysteine lyase activity
LGL92_03930	COG4536	flavin adenine dinucleotide binding
LGL92_03935	COG4137	Cytochrome C assembly protein
LGL92_03940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGL92_03950	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGL92_03955	COG0336	Belongs to the RNA methyltransferase TrmD family
LGL92_03960	COG0335	large ribosomal subunit rRNA binding
LGL92_03965	COG3137	Salt-induced outer membrane protein
LGL92_03970	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL92_03975	COG3279	Response regulator of the LytR AlgR family
LGL92_03980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL92_03985	COG0287	Prephenate dehydrogenase
LGL92_03985	COG1605	Chorismate mutase
LGL92_03990	COG0077	Prephenate dehydratase
LGL92_03990	COG1605	Chorismate mutase
LGL92_04000	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGL92_04005	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL92_04010	COG0564	pseudouridine synthase activity
LGL92_04015	COG1496	oxidoreductase activity
LGL92_04020	COG0542	response to heat
LGL92_04055	COG3021	interspecies interaction between organisms
LGL92_04060	COG1388	LysM domain
LGL92_04060	COG0741	lytic transglycosylase activity
LGL92_04070	COG2226	methyltransferase
LGL92_04080	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL92_04090	COG1960	acyl-CoA dehydrogenase activity
LGL92_04095	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL92_04100	COG0121	glutamine amidotransferase
LGL92_04105	COG3034	peptidoglycan biosynthetic process
LGL92_04115	COG1805	sodium ion transport
LGL92_04120	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL92_04125	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL92_04130	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL92_04140	COG1477	protein flavinylation
LGL92_04145	COG2991	Protein conserved in bacteria
LGL92_04155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL92_04160	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGL92_04165	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LGL92_04170	COG1073	alpha beta
LGL92_04185	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGL92_04220	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL92_04240	COG4126	flavin adenine dinucleotide binding
LGL92_04250	COG2974	May be involved in recombination
LGL92_04255	COG1940	carbohydrate kinase activity
LGL92_04260	COG0419	ATPase involved in DNA repair
LGL92_04265	COG0420	3'-5' exonuclease activity
LGL92_04270	COG0745	RESPONSE REGULATOR receiver
LGL92_04275	COG5002	protein histidine kinase activity
LGL92_04290	COG1113	amino acid transport
LGL92_04295	COG0366	Alpha amylase catalytic
LGL92_04300	COG0300	oxidoreductase activity
LGL92_04305	COG0450	alkyl hydroperoxide reductase
LGL92_04310	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LGL92_04325	COG1862	Preprotein translocase
LGL92_04330	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL92_04335	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL92_04340	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGL92_04345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL92_04345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL92_04350	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGL92_04360	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGL92_04365	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGL92_04370	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGL92_04375	COG0142	geranyltranstransferase activity
LGL92_04410	COG0693	protein deglycase activity
LGL92_04415	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGL92_04420	COG1666	GTP binding
LGL92_04425	COG2814	Major facilitator Superfamily
LGL92_04435	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGL92_04440	COG1845	cytochrome c oxidase, subunit III
LGL92_04445	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGL92_04450	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGL92_04460	COG2223	nitrite transmembrane transporter activity
LGL92_04465	COG3056	Lipoprotein
LGL92_04470	COG0271	Belongs to the BolA IbaG family
LGL92_04480	COG0740	serine-type endopeptidase activity
LGL92_04485	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGL92_04490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL92_04495	COG0776	regulation of translation
LGL92_04500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL92_04505	COG1555	photosystem II stabilization
LGL92_04510	COG0824	Thioesterase
LGL92_04515	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGL92_04520	COG4533	DNA binding
LGL92_04535	COG1522	sequence-specific DNA binding
LGL92_04540	COG1132	(ABC) transporter
LGL92_04545	COG1132	(ABC) transporter
LGL92_04550	COG0347	Belongs to the P(II) protein family
LGL92_04560	COG1946	Acyl-CoA thioesterase
LGL92_04565	COG3695	enzyme binding
LGL92_04590	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL92_04595	COG0254	rRNA binding
LGL92_04600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL92_04605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL92_04610	COG1309	transcriptional regulator
LGL92_04615	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGL92_04620	COG3264	Mechanosensitive ion channel
LGL92_04620	COG1196	nuclear chromosome segregation
LGL92_04635	COG2832	Protein of unknown function (DUF454)
LGL92_04640	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGL92_04680	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGL92_04685	COG0326	Molecular chaperone. Has ATPase activity
LGL92_04700	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL92_04710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL92_04710	COG4651	solute:proton antiporter activity
LGL92_04715	COG0737	Belongs to the 5'-nucleotidase family
LGL92_04720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGL92_04725	COG3735	TraB family
LGL92_04730	COG2217	Heavy metal translocating P-type atpase
LGL92_04735	COG0789	Transcriptional regulator
LGL92_04740	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGL92_04745	COG0330	HflC and HflK could
LGL92_04750	COG3118	belongs to the thioredoxin family
LGL92_04755	COG0300	oxidoreductase activity
LGL92_04760	COG2755	lipolytic protein G-D-S-L family
LGL92_04765	COG4181	ATPase activity
LGL92_04770	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGL92_04775	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGL92_04780	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGL92_04785	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL92_04790	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL92_04815	COG3188	usher protein
LGL92_04820	COG3121	Chaperone
LGL92_04850	COG2501	S4 domain
LGL92_04855	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGL92_04865	COG0582	viral genome integration into host DNA
LGL92_04885	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LGL92_04890	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LGL92_04905	COG0732	type I restriction modification DNA specificity domain
LGL92_04910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LGL92_04940	COG3596	GTP binding
LGL92_04970	COG2003	Belongs to the UPF0758 family
LGL92_05000	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGL92_05005	COG1393	Belongs to the ArsC family
LGL92_05015	COG1022	Amp-dependent synthetase and ligase
LGL92_05040	COG3038	cytochrome b561
LGL92_05070	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGL92_05080	COG1215	transferase activity, transferring glycosyl groups
LGL92_05100	COG3250	beta-galactosidase activity
LGL92_05115	COG1309	transcriptional regulator
LGL92_05145	COG2197	response regulator
LGL92_05150	COG1278	Cold shock
LGL92_05170	COG3706	GGDEF domain
LGL92_05180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGL92_05190	COG2921	Belongs to the UPF0250 family
LGL92_05195	COG1686	Belongs to the peptidase S11 family
LGL92_05200	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL92_05205	COG0772	Belongs to the SEDS family
LGL92_05210	COG0768	penicillin binding
LGL92_05215	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGL92_05220	COG0799	negative regulation of ribosome biogenesis
LGL92_05225	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGL92_05230	COG1466	dna polymerase III delta subunit
LGL92_05235	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LGL92_05245	COG2888	peptidyl-tyrosine sulfation
LGL92_05250	COG1126	abc transporter atp-binding protein
LGL92_05255	COG0765	amino acid transport
LGL92_05260	COG0765	amino acid transport
LGL92_05270	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGL92_05275	COG4535	Mg2 and Co2 transporter CorC
LGL92_05280	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGL92_05285	COG1702	phosphate starvation-inducible protein PhoH
LGL92_05290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGL92_05295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL92_05330	COG0367	asparagine synthase
LGL92_05335	COG0647	UMP catabolic process
LGL92_05340	COG1846	Transcriptional regulator
LGL92_05340	COG1940	carbohydrate kinase activity
LGL92_05345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL92_05355	COG2190	(PTS) system
LGL92_05355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL92_05355	COG1263	PTS System
LGL92_05380	COG0735	belongs to the Fur family
LGL92_05390	COG0840	transmembrane signaling receptor activity
LGL92_05400	COG0596	Alpha beta hydrolase
LGL92_05405	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LGL92_05410	COG0033	Phosphoglucomutase
LGL92_05420	COG0745	RESPONSE REGULATOR receiver
LGL92_05425	COG2205	protein histidine kinase activity
LGL92_05430	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LGL92_05435	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGL92_05455	COG3272	Protein of unknown function (DUF1722)
LGL92_05460	COG0415	Belongs to the DNA photolyase family
LGL92_05465	COG5212	phosphodiesterase
LGL92_05470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGL92_05475	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGL92_05480	COG1984	allophanate hydrolase subunit 2
LGL92_05485	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGL92_05520	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGL92_05525	COG1053	succinate dehydrogenase
LGL92_05530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL92_05535	COG0567	Dehydrogenase, E1 component
LGL92_05540	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL92_05545	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL92_05550	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGL92_05555	COG0737	Belongs to the 5'-nucleotidase family
LGL92_05560	COG1271	oxidase subunit
LGL92_05565	COG1294	oxidase, subunit
LGL92_05570	COG4890	Cyd operon protein YbgT
LGL92_05575	COG3790	cyd operon protein YbgE
LGL92_05580	COG0824	Thioesterase
LGL92_05585	COG0811	peptide transport
LGL92_05590	COG0848	biopolymer transport protein
LGL92_05595	COG3064	Membrane
LGL92_05595	COG3064	Membrane
LGL92_05600	COG0823	Involved in the tonB-independent uptake of proteins
LGL92_05605	COG2885	chlorophyll binding
LGL92_05610	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LGL92_05650	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGL92_05660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL92_05660	COG2205	protein histidine kinase activity
LGL92_05670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL92_05675	COG0588	phosphoglycerate mutase activity
LGL92_05685	COG2017	converts alpha-aldose to the beta-anomer
LGL92_05695	COG1085	galactose-1-phosphate uridylyltransferase
LGL92_05700	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGL92_05715	COG2005	Transcriptional regulator
LGL92_05715	COG3585	molybdate ion transport
LGL92_05725	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGL92_05730	COG4149	molybdate abc transporter
LGL92_05740	COG0561	phosphatase activity
LGL92_05745	COG2706	6-phosphogluconolactonase activity
LGL92_05760	COG0156	8-amino-7-oxononanoate synthase activity
LGL92_05765	COG2226	methyltransferase
LGL92_05780	COG0556	nucleotide-excision repair
LGL92_05785	COG4628	conserved protein (DUF2132)
LGL92_05800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL92_05805	COG1120	ATPase activity
LGL92_05810	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGL92_05815	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGL92_05825	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGL92_05830	COG0314	molybdopterin synthase activity
LGL92_05835	COG0670	Belongs to the BI1 family
LGL92_05840	COG0842	Transport permease protein
LGL92_05845	COG0842	Transport permease protein
LGL92_05850	COG1131	(ABC) transporter
LGL92_05855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL92_05860	COG1309	transcriptional regulator
LGL92_05865	COG0513	Belongs to the DEAD box helicase family
LGL92_05870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL92_05880	COG1686	Belongs to the peptidase S11 family
LGL92_05885	COG0277	FAD linked oxidase domain protein
LGL92_05905	COG2261	transglycosylase associated protein
LGL92_05915	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LGL92_05930	COG4807	Protein conserved in bacteria
LGL92_05935	COG2897	thiosulfate sulfurtransferase activity
LGL92_05940	COG1732	Glycine betaine
LGL92_05945	COG1174	glycine betaine transport
LGL92_05950	COG1125	glycine betaine transport
LGL92_05955	COG1174	glycine betaine transport
LGL92_05960	COG0531	amino acid
LGL92_05965	COG1982	Orn Lys Arg decarboxylase major
LGL92_05975	COG0697	spore germination
LGL92_05990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGL92_05995	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LGL92_06000	COG1126	abc transporter atp-binding protein
LGL92_06005	COG0765	amino acid transport
LGL92_06010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL92_06025	COG5006	permease, DMT superfamily
LGL92_06030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGL92_06035	COG2239	Acts as a magnesium transporter
LGL92_06040	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL92_06045	COG0488	(ABC) transporter
LGL92_06050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL92_06055	COG0303	'Molybdopterin
LGL92_06075	COG0583	DNA-binding transcription factor activity
LGL92_06080	COG0477	Major facilitator Superfamily
LGL92_06085	COG0302	gtp cyclohydrolase
LGL92_06090	COG2311	Membrane
LGL92_06115	COG2949	membrane
LGL92_06120	COG0281	malic enzyme
LGL92_06130	COG0583	DNA-binding transcription factor activity
LGL92_06140	COG1346	cytolysis
LGL92_06145	COG1380	Effector of murein hydrolase LrgA
LGL92_06155	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL92_06155	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL92_06160	COG0489	protein tyrosine kinase activity
LGL92_06165	COG0572	uridine kinase
LGL92_06170	COG0717	Belongs to the dCTP deaminase family
LGL92_06175	COG2982	Protein involved in outer membrane biogenesis
LGL92_06180	COG3069	C4-dicarboxylate transmembrane transporter activity
LGL92_06185	COG1253	flavin adenine dinucleotide binding
LGL92_06190	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL92_06195	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL92_06200	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGL92_06210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGL92_06210	COG0140	phosphoribosyl-ATP diphosphatase activity
LGL92_06220	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGL92_06230	COG0131	Imidazoleglycerol-phosphate dehydratase
LGL92_06230	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL92_06235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGL92_06240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGL92_06255	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL92_06260	COG0625	glutathione transferase activity
LGL92_06275	COG0626	cystathionine gamma-synthase activity
LGL92_06285	COG1686	Belongs to the peptidase S11 family
LGL92_06290	COG1760	l-serine dehydratase
LGL92_06295	COG0814	amino acid
LGL92_06300	COG1349	DNA-binding transcription factor activity
LGL92_06310	COG0671	phosphoesterase, PA-phosphatase related
LGL92_06370	COG0569	domain protein
LGL92_06370	COG2985	domain, Protein
LGL92_06390	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGL92_06395	COG3842	ATPase activity
LGL92_06400	COG1176	ABC-type spermidine putrescine transport system, permease component I
LGL92_06420	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL92_06425	COG4160	amino acid transport
LGL92_06430	COG4215	(ABC) transporter
LGL92_06435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL92_06440	COG1126	abc transporter atp-binding protein
LGL92_06450	COG0393	Putative heavy-metal-binding
LGL92_06455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL92_06460	COG0702	epimerase
LGL92_06465	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LGL92_06470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL92_06475	COG1151	hydroxylamine reductase activity
LGL92_06480	COG2431	L-lysine efflux transmembrane transporter activity
LGL92_06485	COG3593	DNA synthesis involved in DNA repair
LGL92_06495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL92_06505	COG1278	Cold shock
LGL92_06510	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGL92_06515	COG0542	response to heat
LGL92_06520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGL92_06530	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGL92_06540	COG0492	ferredoxin-NADP+ reductase activity
LGL92_06545	COG1522	sequence-specific DNA binding
LGL92_06550	COG1674	ftsk spoiiie
LGL92_06550	COG3107	peptidoglycan biosynthetic process
LGL92_06555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGL92_06560	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGL92_06565	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGL92_06570	COG2814	Major facilitator Superfamily
LGL92_06575	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGL92_06580	COG1882	Formate acetyltransferase
LGL92_06585	COG2116	formate transmembrane transporter activity
LGL92_06590	COG1944	ATP diphosphatase activity
LGL92_06595	COG0252	asparaginase activity
LGL92_06605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGL92_06615	COG0539	negative regulation of cytoplasmic translation
LGL92_06625	COG0658	competence protein
LGL92_06625	COG2333	competence protein COMEC
LGL92_06635	COG1663	tetraacyldisaccharide 4'-kinase activity
LGL92_06640	COG5383	Protein conserved in bacteria
LGL92_06650	COG1278	Cold shock
LGL92_06655	COG2835	tetraacyldisaccharide 4'-kinase activity
LGL92_06660	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LGL92_06665	COG3173	Aminoglycoside phosphotransferase
LGL92_06670	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LGL92_06675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL92_06680	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LGL92_06690	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LGL92_06695	COG2989	Protein conserved in bacteria
LGL92_06700	COG3108	Peptidase M15
LGL92_06705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGL92_06710	COG1448	Aminotransferase
LGL92_06725	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGL92_06730	COG0308	aminopeptidase N
LGL92_06735	COG0167	dihydroorotate dehydrogenase activity
LGL92_06750	COG0116	Belongs to the methyltransferase superfamily
LGL92_06750	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL92_06755	COG0488	(ABC) transporter
LGL92_06760	COG2995	paraquat-inducible protein a
LGL92_06765	COG3008	intermembrane lipid transfer
LGL92_06765	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL92_06770	COG3009	Protein conserved in bacteria
LGL92_06775	COG3130	regulation of translation
LGL92_06780	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGL92_06785	COG1067	ATP-dependent peptidase activity
LGL92_06790	COG3120	sequence-specific DNA binding
LGL92_06800	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LGL92_06805	COG3070	regulator of competence-specific genes
LGL92_06810	COG1289	transmembrane transporter activity
LGL92_06815	COG3304	Inner membrane component domain
LGL92_06820	COG0210	DNA helicase
LGL92_06825	COG1803	Methylglyoxal synthase
LGL92_06835	COG1832	CoA-binding protein
LGL92_06840	COG3785	DNA binding
LGL92_06845	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL92_06850	COG1254	Belongs to the acylphosphatase family
LGL92_06855	COG2920	part of a sulfur-relay system
LGL92_06865	COG0288	reversible hydration of carbon dioxide
LGL92_06885	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LGL92_06890	COG2943	transferase activity, transferring hexosyl groups
LGL92_06910	COG1560	Kdo2-lipid A biosynthetic process
LGL92_06920	COG0628	permease
LGL92_06945	COG0418	dihydroorotase activity
LGL92_06950	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LGL92_06960	COG1530	ribonuclease E activity
LGL92_06965	COG0564	pseudouridine synthase activity
LGL92_06970	COG0424	maF-like protein
LGL92_06975	COG1399	metal-binding, possibly nucleic acid-binding protein
LGL92_06980	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGL92_06990	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGL92_06995	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGL92_07005	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL92_07010	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL92_07015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGL92_07020	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGL92_07025	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGL92_07030	COG0470	DNA polymerase III
LGL92_07035	COG0084	hydrolase, TatD family'
LGL92_07040	COG1263	PTS System
LGL92_07040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL92_07045	COG0537	adenosine 5'-monophosphoramidase activity
LGL92_07050	COG5633	Lipoprotein
LGL92_07055	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LGL92_07070	COG3150	esterase
LGL92_07075	COG1252	NADH dehydrogenase
LGL92_07080	COG3134	Outer membrane lipoprotein
LGL92_07085	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGL92_07090	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL92_07100	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL92_07120	COG2850	peptidyl-arginine hydroxylation
LGL92_07125	COG2205	protein histidine kinase activity
LGL92_07130	COG0745	RESPONSE REGULATOR receiver
LGL92_07140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGL92_07145	COG2915	High frequency lysogenization protein hflD homolog
LGL92_07150	COG0482	sulfurtransferase activity
LGL92_07160	COG1187	pseudouridine synthase activity
LGL92_07165	COG0538	isocitrate dehydrogenase activity
LGL92_07170	COG2771	luxR family
LGL92_07175	COG3916	Acyl-homoserine-lactone synthase
LGL92_07180	COG2723	6-phospho-beta-galactosidase activity
LGL92_07190	COG0339	signal peptide processing
LGL92_07195	COG0840	transmembrane signaling receptor activity
LGL92_07200	COG3493	citrate carrier protein
LGL92_07205	COG4565	transcriptional regulatory protein
LGL92_07210	COG3290	protein histidine kinase activity
LGL92_07215	COG0471	metal ion transport
LGL92_07260	COG4977	sequence-specific DNA binding
LGL92_07265	COG1702	phosphate starvation-inducible protein PhoH
LGL92_07270	COG0387	Pfam Sodium calcium exchanger
LGL92_07275	COG2375	cellular response to nickel ion
LGL92_07280	COG3850	Histidine kinase
LGL92_07290	COG1294	oxidase, subunit
LGL92_07295	COG1271	oxidase subunit
LGL92_07300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL92_07305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGL92_07310	COG3138	arginine N-succinyltransferase
LGL92_07320	COG3724	N-succinylarginine dihydrolase activity
LGL92_07340	COG1228	amidohydrolase
LGL92_07350	COG0402	S-adenosylhomocysteine deaminase activity
LGL92_07370	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL92_07375	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LGL92_07380	COG3383	formate dehydrogenase (NAD+) activity
LGL92_07385	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL92_07390	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGL92_07400	COG3260	NADH ubiquinone oxidoreductase 20
LGL92_07405	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL92_07410	COG3261	NADH dehydrogenase
LGL92_07410	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LGL92_07415	COG0650	Formate hydrogenlyase subunit 4
LGL92_07420	COG0651	ATP synthesis coupled electron transport
LGL92_07425	COG0651	ATP synthesis coupled electron transport
LGL92_07430	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL92_07440	COG0375	protein maturation
LGL92_07445	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LGL92_07450	COG0298	carbon dioxide binding
LGL92_07455	COG0409	Hydrogenase expression formation protein
LGL92_07460	COG0309	Hydrogenase expression formation protein (HypE)
LGL92_07500	COG3708	Transcriptional regulator
LGL92_07500	COG2207	Transcriptional regulator
LGL92_07505	COG0012	GTP binding
LGL92_07515	COG0193	aminoacyl-tRNA hydrolase activity
LGL92_07525	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGL92_07535	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGL92_07540	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGL92_07545	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGL92_07550	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL92_07565	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LGL92_07570	COG0659	secondary active sulfate transmembrane transporter activity
LGL92_07575	COG3706	GGDEF domain
LGL92_07600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL92_07610	COG3381	protein complex oligomerization
LGL92_07630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL92_07645	COG0728	peptidoglycan biosynthetic process
LGL92_07680	COG3102	Protein conserved in bacteria
LGL92_07685	COG3142	Participates in the control of copper homeostasis
LGL92_07700	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LGL92_07705	COG1801	Protein of unknown function DUF72
LGL92_07715	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGL92_07720	COG0494	nUDIX hydrolase
LGL92_07730	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LGL92_07740	COG2255	four-way junction helicase activity
LGL92_07745	COG3104	oligopeptide transport
LGL92_07750	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL92_07755	COG1121	(ABC) transporter
LGL92_07760	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LGL92_07765	COG0739	heme binding
LGL92_07770	COG1560	Kdo2-lipid A biosynthetic process
LGL92_07775	COG0469	pyruvate kinase activity
LGL92_07780	COG1737	Transcriptional regulator
LGL92_07785	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGL92_07790	COG0800	Aldolase
LGL92_07800	COG2076	Multidrug Resistance protein
LGL92_07805	COG0251	oxidation-reduction process
LGL92_07810	COG1199	ATP-dependent helicase activity
LGL92_07815	COG1214	PFAM Peptidase M22, glycoprotease
LGL92_07820	COG3065	identical protein binding
LGL92_07825	COG0318	PFAM AMP-dependent synthetase and ligase
LGL92_07830	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LGL92_07835	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LGL92_07840	COG2894	cell division
LGL92_07845	COG0850	regulation of cytokinetic process
LGL92_07850	COG3100	YcgL domain-containing protein
LGL92_07855	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGL92_07860	COG2983	Belongs to the UPF0260 family
LGL92_07880	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL92_07890	COG2719	SpoVR family
LGL92_07895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGL92_07900	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGL92_07905	COG2814	Major facilitator Superfamily
LGL92_07915	COG2200	EAL domain
LGL92_07915	COG2202	Pas domain
LGL92_07915	COG2199	diguanylate cyclase activity
LGL92_07935	COG2718	Belongs to the UPF0229 family
LGL92_07940	COG2766	serine protein kinase
LGL92_07950	COG3713	MltA-interacting MipA family protein
LGL92_07955	COG2194	sulfuric ester hydrolase activity
LGL92_07970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL92_07975	COG3139	Protein of unknown function (DUF1315)
LGL92_07980	COG1335	isochorismatase
LGL92_07985	COG0252	asparaginase activity
LGL92_07990	COG0616	signal peptide processing
LGL92_07995	COG0778	Nitroreductase
LGL92_08005	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL92_08015	COG0494	nUDIX hydrolase
LGL92_08020	COG0708	Exodeoxyribonuclease III
LGL92_08050	COG0788	formyltetrahydrofolate deformylase activity
LGL92_08055	COG3012	SEC-C Motif Domain Protein
LGL92_08065	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGL92_08070	COG0745	RESPONSE REGULATOR receiver
LGL92_08090	COG1012	belongs to the aldehyde dehydrogenase family
LGL92_08090	COG1454	alcohol dehydrogenase
LGL92_08100	COG2095	MarC family integral membrane protein
LGL92_08105	COG4166	transmembrane transport
LGL92_08120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL92_08135	COG3099	Belongs to the UPF0263 family
LGL92_08140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL92_08160	COG2350	Protein conserved in bacteria
LGL92_08175	COG3710	Transcriptional regulator
LGL92_08210	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LGL92_08235	COG0727	PFAM Uncharacterised protein family (UPF0153)
LGL92_08240	COG3047	cAMP biosynthetic process
LGL92_08255	COG0133	tryptophan synthase activity
LGL92_08260	COG0134	indole-3-glycerol-phosphate synthase activity
LGL92_08260	COG0135	phosphoribosylanthranilate isomerase activity
LGL92_08270	COG0512	Glutamine amidotransferase of anthranilate synthase
LGL92_08280	COG0613	PHP domain protein
LGL92_08285	COG0009	L-threonylcarbamoyladenylate synthase
LGL92_08290	COG1187	pseudouridine synthase activity
LGL92_08305	COG0616	signal peptide processing
LGL92_08320	COG0583	DNA-binding transcription factor activity
LGL92_08335	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGL92_08345	COG0671	phosphoesterase, PA-phosphatase related
LGL92_08350	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LGL92_08355	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LGL92_08375	COG0023	Translation Initiation Factor
LGL92_08385	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL92_08390	COG3447	MASE1 domain protein
LGL92_08390	COG5001	Diguanylate cyclase
LGL92_08390	COG5002	protein histidine kinase activity
LGL92_08395	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LGL92_08400	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGL92_08410	COG4659	FMN binding
LGL92_08420	COG3708	Transcriptional regulator
LGL92_08420	COG2207	Transcriptional regulator
LGL92_08435	COG4657	Part of a membrane complex involved in electron transport
LGL92_08445	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGL92_08455	COG0673	inositol 2-dehydrogenase activity
LGL92_08460	COG0385	Bile acid
LGL92_08465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGL92_08470	COG5339	Protein conserved in bacteria
LGL92_08475	COG1482	cell wall glycoprotein biosynthetic process
LGL92_08480	COG0114	fumarate hydratase activity
LGL92_08490	COG1940	carbohydrate kinase activity
LGL92_08495	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGL92_08515	COG1742	UPF0060 membrane protein
LGL92_08520	COG4221	oxidoreductase activity
LGL92_08525	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL92_08545	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL92_08575	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LGL92_08595	COG1011	Hydrolase
LGL92_08605	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGL92_08610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGL92_08615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL92_08620	COG0589	response to stress
LGL92_08650	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGL92_08655	COG3623	hexulose-6-phosphate isomerase
LGL92_08660	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LGL92_08665	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LGL92_08675	COG0531	amino acid
LGL92_08685	COG0745	RESPONSE REGULATOR receiver
LGL92_08690	COG2205	protein histidine kinase activity
LGL92_08705	COG2207	Transcriptional regulator
LGL92_08710	COG1881	PFAM PEBP family protein
LGL92_08720	COG3591	Belongs to the peptidase S1B family
LGL92_08725	COG1643	Atp-dependent helicase
LGL92_08730	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGL92_08735	COG3784	Protein of unknown function (DUF1318)
LGL92_08750	COG2911	Protein conserved in bacteria
LGL92_08755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGL92_08760	COG3187	Heat shock protein
LGL92_08765	COG3042	response to heat
LGL92_08770	COG1285	pathogenesis
LGL92_08780	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGL92_08780	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGL92_08780	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGL92_08780	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL92_08795	COG4166	transmembrane transport
LGL92_08800	COG2866	Carboxypeptidase
LGL92_08805	COG4948	Mandelate Racemase Muconate Lactonizing
LGL92_08810	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGL92_08820	COG5642	Protein of unknown function (DUF2384)
LGL92_08825	COG5654	RES domain protein
LGL92_08830	COG3768	UPF0283 membrane protein
LGL92_08835	COG3106	COG3106 Predicted ATPase
LGL92_08845	COG1983	PspC domain protein
LGL92_08855	COG1842	Phage shock protein A
LGL92_08875	COG4166	transmembrane transport
LGL92_08885	COG4171	peptide transport system, permease
LGL92_08890	COG4172	Belongs to the ABC transporter superfamily
LGL92_08895	COG4172	Belongs to the ABC transporter superfamily
LGL92_08905	COG3104	oligopeptide transport
LGL92_08915	COG0484	heat shock protein binding
LGL92_08960	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGL92_08965	COG3133	Outer membrane lipoprotein
LGL92_08970	COG1846	Transcriptional regulator
LGL92_08980	COG4989	oxidoreductase activity
LGL92_08985	COG3313	Fe-S protein
LGL92_08990	COG2194	sulfuric ester hydrolase activity
LGL92_08995	COG1309	transcriptional regulator
LGL92_09000	COG1902	pentaerythritol trinitrate reductase activity
LGL92_09015	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGL92_09020	COG0791	NLP P60 protein
LGL92_09025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL92_09035	COG1609	Transcriptional regulator
LGL92_09040	COG0583	DNA-binding transcription factor activity
LGL92_09045	COG2814	Major facilitator Superfamily
LGL92_09050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL92_09055	COG0307	riboflavin synthase, alpha
LGL92_09090	COG1376	ErfK ybiS ycfS ynhG family protein
LGL92_09090	COG1388	LysM domain
LGL92_09095	COG2166	iron-sulfur cluster assembly
LGL92_09105	COG0719	Fe-S assembly protein
LGL92_09110	COG0396	ATPase activity
LGL92_09115	COG0719	Fe-S assembly protein
LGL92_09120	COG0316	Belongs to the HesB IscA family
LGL92_09125	COG2050	protein possibly involved in aromatic compounds catabolism
LGL92_09130	COG0247	lactate metabolic process
LGL92_09130	COG0277	FAD linked oxidase domain protein
LGL92_09135	COG0628	permease
LGL92_09145	COG0574	Belongs to the PEP-utilizing enzyme family
LGL92_09145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL92_09150	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGL92_09155	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL92_09165	COG4771	TonB-dependent receptor
LGL92_09170	COG3720	iron ion transport
LGL92_09175	COG4558	Periplasmic binding protein
LGL92_09180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL92_09185	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LGL92_09195	COG0095	Lipoate-protein ligase
LGL92_09200	COG0791	NLP P60 protein
LGL92_09205	COG2076	Multidrug Resistance protein
LGL92_09210	COG2076	Multidrug Resistance protein
LGL92_09215	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGL92_09235	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL92_09245	COG4139	cobalamin transport
LGL92_09290	COG0776	regulation of translation
LGL92_09365	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGL92_09370	COG1121	(ABC) transporter
LGL92_09375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL92_09380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL92_09385	COG3001	Fructosamine kinase
LGL92_09395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL92_09400	COG1988	membrane-bound metal-dependent
LGL92_09405	COG1823	symporter activity
LGL92_09410	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL92_09420	COG2814	Major facilitator Superfamily
LGL92_09430	COG0501	Belongs to the peptidase M48B family
LGL92_09435	COG0793	Belongs to the peptidase S41A family
LGL92_09445	COG1956	GAF domain-containing protein
LGL92_09450	COG2995	paraquat-inducible protein a
LGL92_09455	COG3008	intermembrane lipid transfer
LGL92_09460	COG2203	Gaf domain
LGL92_09460	COG4251	negative regulation of phosphorylation
LGL92_09460	COG5001	Diguanylate cyclase
LGL92_09460	COG3706	GGDEF domain
LGL92_09540	COG1276	copper resistance
LGL92_09545	COG2372	response to copper ion
LGL92_09550	COG1528	Iron-storage protein
LGL92_09565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL92_09570	COG1770	oligopeptidase
LGL92_09580	COG3097	Belongs to the UPF0267 family
LGL92_09585	COG3141	response to X-ray
LGL92_09590	COG0513	Belongs to the DEAD box helicase family
LGL92_09610	COG0494	nUDIX hydrolase
LGL92_09615	COG1760	l-serine dehydratase
LGL92_09620	COG1253	flavin adenine dinucleotide binding
LGL92_09625	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL92_09625	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL92_09630	COG3715	PTS system
LGL92_09635	COG3716	PTS system mannose fructose sorbose family IID component
LGL92_09640	COG4811	Protein of unknown function (DUF986)
LGL92_09645	COG1971	Probably functions as a manganese efflux pump
LGL92_09665	COG1960	acyl-CoA dehydrogenase activity
LGL92_09675	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGL92_09705	COG2226	methyltransferase
LGL92_09710	COG0768	penicillin binding
LGL92_09715	COG1496	oxidoreductase activity
LGL92_09735	COG1113	amino acid transport
LGL92_09770	COG2207	Transcriptional regulator
LGL92_09790	COG1132	(ABC) transporter
LGL92_09800	COG2203	Gaf domain
LGL92_09800	COG3706	GGDEF domain
LGL92_09800	COG4251	negative regulation of phosphorylation
LGL92_09800	COG5001	Diguanylate cyclase
LGL92_09820	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGL92_09840	COG1278	Cold shock
LGL92_09845	COG1278	Cold shock
LGL92_09860	COG1917	Cupin 2, conserved barrel domain protein
LGL92_09860	COG2169	Transcriptional regulator
LGL92_09865	COG1447	Phosphotransferase system cellobiose-specific component IIA
LGL92_09870	COG2723	6-phospho-beta-galactosidase activity
LGL92_09875	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL92_09880	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL92_09885	COG1187	pseudouridine synthase activity
LGL92_09895	COG3122	Protein conserved in bacteria
LGL92_09900	COG1757	Na H antiporter
LGL92_09915	COG2235	arginine
LGL92_09930	COG0076	glutamate decarboxylase activity
LGL92_09935	COG0531	amino acid
LGL92_09970	COG2153	protein acetylation
LGL92_09975	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGL92_10005	COG0840	transmembrane signaling receptor activity
LGL92_10010	COG2801	Transposase and inactivated derivatives
LGL92_10155	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LGL92_10170	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL92_10325	COG3179	chitinase
LGL92_10460	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGL92_10465	COG0322	excinuclease ABC activity
LGL92_10470	COG2197	response regulator
LGL92_10495	COG1113	amino acid transport
LGL92_10505	COG0531	amino acid
LGL92_10510	COG3710	Transcriptional regulator
LGL92_10515	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL92_10520	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL92_10520	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL92_10520	COG0506	proline dehydrogenase activity
LGL92_10525	COG1126	abc transporter atp-binding protein
LGL92_10530	COG0765	amino acid transport
LGL92_10535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL92_10540	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGL92_10550	COG1191	sigma factor activity
LGL92_10590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGL92_10595	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL92_10610	COG1677	Flagellar hook-basal body complex protein FliE
LGL92_10620	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGL92_10625	COG1317	bacterial-type flagellum organization
LGL92_10630	COG1157	protein secretion by the type III secretion system
LGL92_10645	COG1580	Controls the rotational direction of flagella during chemotaxis
LGL92_10725	COG1558	bacterial-type flagellum-dependent cell motility
LGL92_10730	COG1815	bacterial-type flagellum-dependent cell motility
LGL92_10740	COG2747	anti-sigma28 factor FlgM
LGL92_10745	COG3418	PFAM FlgN family protein
LGL92_10755	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL92_10760	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL92_10765	COG4935	Belongs to the peptidase S8 family
LGL92_10765	COG1404	Belongs to the peptidase S8 family
LGL92_10770	COG2197	response regulator
LGL92_10785	COG3188	usher protein
LGL92_10795	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LGL92_10800	COG0745	RESPONSE REGULATOR receiver
LGL92_10810	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGL92_10815	COG0840	transmembrane signaling receptor activity
LGL92_10820	COG0840	transmembrane signaling receptor activity
LGL92_10830	COG0835	chemotaxis
LGL92_10835	COG2198	Histidine kinase
LGL92_10835	COG0643	Histidine kinase
LGL92_10840	COG1360	Flagellar Motor Protein
LGL92_10860	COG0589	response to stress
LGL92_10865	COG1285	pathogenesis
LGL92_10870	COG0840	transmembrane signaling receptor activity
LGL92_10890	COG1609	Transcriptional regulator
LGL92_10900	COG0604	alcohol dehydrogenase
LGL92_10900	COG1028	Short-chain dehydrogenase reductase Sdr
LGL92_10900	COG3321	synthase
LGL92_10950	COG0471	metal ion transport
LGL92_10965	COG3051	citrate lyase alpha subunit
LGL92_10970	COG2301	Belongs to the HpcH HpaI aldolase family
LGL92_10975	COG3052	prosthetic group binding
LGL92_10980	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LGL92_10985	COG3290	protein histidine kinase activity
LGL92_10990	COG4565	transcriptional regulatory protein
LGL92_11005	COG2271	Major facilitator Superfamily
LGL92_11010	COG1840	ABC-type Fe3 transport system, periplasmic component
LGL92_11020	COG3842	ATPase activity
LGL92_11035	COG0582	viral genome integration into host DNA
LGL92_11050	COG3423	Transcriptional regulator
LGL92_11085	COG3451	type IV secretory pathway VirB4
LGL92_11105	COG3736	Type IV secretory pathway, component VirB8
LGL92_11120	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LGL92_11135	COG4227	nucleotidyltransferase activity
LGL92_11185	COG1289	transmembrane transporter activity
LGL92_11195	COG2925	Exonuclease
LGL92_11200	COG0531	amino acid
LGL92_11205	COG4771	TonB-dependent receptor
LGL92_11215	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL92_11225	COG0833	amino acid
LGL92_11230	COG0583	DNA-binding transcription factor activity
LGL92_11240	COG2855	membrane
LGL92_11245	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGL92_11250	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGL92_11250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL92_11250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL92_11255	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL92_11270	COG3005	denitrification pathway
LGL92_11275	COG0243	molybdopterin cofactor binding
LGL92_11295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGL92_11305	COG0246	Mannitol dehydrogenase
LGL92_11315	COG0523	cobalamin synthesis protein
LGL92_11320	COG0671	phosphoesterase, PA-phosphatase related
LGL92_11325	COG0791	NLP P60 protein
LGL92_11330	COG2200	EAL domain
LGL92_11335	COG4166	transmembrane transport
LGL92_11340	COG4174	ABC transporter (Permease)
LGL92_11345	COG4239	(ABC) transporter, permease
LGL92_11350	COG4172	Belongs to the ABC transporter superfamily
LGL92_11360	COG2814	Major facilitator Superfamily
LGL92_11365	COG1187	pseudouridine synthase activity
LGL92_11370	COG1061	Type III restriction enzyme res subunit
LGL92_11385	COG3082	Protein of unknown function (DUF1414)
LGL92_11390	COG3083	sulfuric ester hydrolase activity
LGL92_11400	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LGL92_11430	COG3299	homolog of phage Mu protein gp47
LGL92_11480	COG4386	tail sheath protein
LGL92_11520	COG0616	signal peptide processing
LGL92_11555	COG3646	Phage regulatory protein
LGL92_11565	COG0675	Transposase, IS605 OrfB family
LGL92_11600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGL92_11605	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL92_11625	COG2223	nitrite transmembrane transporter activity
LGL92_11630	COG2198	Histidine kinase
LGL92_11630	COG0642	Histidine kinase
LGL92_11640	COG0784	Response regulator, receiver
LGL92_11640	COG2205	protein histidine kinase activity
LGL92_11650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL92_11655	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL92_11665	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL92_11675	COG4574	serine-type endopeptidase inhibitor activity
LGL92_11685	COG2246	polysaccharide biosynthetic process
LGL92_11700	COG0814	amino acid
LGL92_11725	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGL92_11730	COG0596	Alpha beta hydrolase
LGL92_11735	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGL92_11740	COG1169	isochorismate synthase
LGL92_11745	COG4575	ribosome binding
LGL92_11760	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL92_11765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGL92_11775	COG0839	Belongs to the complex I subunit 6 family
LGL92_11780	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL92_11785	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGL92_11790	COG1034	ATP synthesis coupled electron transport
LGL92_11810	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL92_11815	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL92_11820	COG0583	DNA-binding transcription factor activity
LGL92_11825	COG0436	Aminotransferase
LGL92_11830	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL92_11835	COG0490	domain, Protein
LGL92_11835	COG0471	metal ion transport
LGL92_11845	COG3013	Belongs to the UPF0304 family
LGL92_11850	COG3092	negative regulation of chromosome organization
LGL92_11860	COG0857	belongs to the CobB CobQ family
LGL92_11860	COG0280	phosphate acetyltransferase
LGL92_11865	COG1609	Transcriptional regulator
LGL92_11880	COG3037	sugar-specific permease SgaT UlaA
LGL92_11885	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LGL92_11890	COG0622	Phosphoesterase
LGL92_11900	COG0625	glutathione transferase activity
LGL92_11905	COG1090	epimerase
LGL92_11915	COG4160	amino acid transport
LGL92_11920	COG4215	(ABC) transporter
LGL92_11935	COG0163	prenyltransferase activity
LGL92_11940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGL92_11945	COG1286	toxin biosynthetic process
LGL92_11950	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LGL92_11955	COG0285	dihydrofolate synthase activity
LGL92_11965	COG0586	Pfam SNARE associated Golgi protein
LGL92_11975	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL92_12000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL92_12005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL92_12035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL92_12050	COG3101	peptidyl-lysine hydroxylation
LGL92_12055	COG0730	response to heat
LGL92_12060	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LGL92_12070	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL92_12075	COG2840	Smr protein MutS2
LGL92_12080	COG2062	phosphohistidine phosphatase, SixA
LGL92_12090	COG0183	Belongs to the thiolase family
LGL92_12095	COG3691	Protein conserved in bacteria
LGL92_12110	COG3088	subunit of a heme lyase
LGL92_12110	COG4235	cytochrome complex assembly
LGL92_12115	COG4235	cytochrome complex assembly
LGL92_12115	COG3088	subunit of a heme lyase
LGL92_12120	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL92_12125	COG1138	Cytochrome C-type biogenesis protein
LGL92_12130	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LGL92_12135	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL92_12140	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL92_12145	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL92_12165	COG2824	Alkylphosphonate utilization operon protein PhnA
LGL92_12170	COG2951	lytic endotransglycosylase activity
LGL92_12175	COG1598	PFAM Uncharacterised protein family UPF0150
LGL92_12185	COG3038	cytochrome b561
LGL92_12190	COG0436	Aminotransferase
LGL92_12200	COG3275	phosphorelay sensor kinase activity
LGL92_12205	COG3279	Response regulator of the LytR AlgR family
LGL92_12210	COG2223	nitrite transmembrane transporter activity
LGL92_12215	COG0837	glucose binding
LGL92_12235	COG1914	H( )-stimulated, divalent metal cation uptake system
LGL92_12240	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL92_12300	COG3530	Putative quorum-sensing-regulated virulence factor
LGL92_12305	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL92_12315	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LGL92_12325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL92_12340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL92_12350	COG4208	sulfate ABC transporter
LGL92_12355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGL92_12360	COG4150	thiosulfate binding
LGL92_12370	COG1737	Transcriptional regulator
LGL92_12375	COG2731	YhcH YjgK YiaL family protein
LGL92_12390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL92_12395	COG2837	iron assimilation
LGL92_12405	COG3111	PFAM Bacterial OB fold (BOF) protein
LGL92_12510	COG1671	Belongs to the UPF0178 family
LGL92_12515	COG0281	malic enzyme
LGL92_12515	COG0280	phosphate acetyltransferase
LGL92_12520	COG0494	nUDIX hydrolase
LGL92_12525	COG3005	denitrification pathway
LGL92_12530	COG3043	anaerobic respiration
LGL92_12535	COG0243	molybdopterin cofactor binding
LGL92_12540	COG3062	negative regulation of establishment of protein localization
LGL92_12545	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL92_12545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL92_12550	COG2197	response regulator
LGL92_12560	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL92_12570	COG1605	Chorismate mutase
LGL92_12575	COG1393	Belongs to the ArsC family
LGL92_12580	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGL92_12585	COG1876	peptidase activity
LGL92_12595	COG0400	carboxylic ester hydrolase activity
LGL92_12615	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LGL92_12620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL92_12625	COG2716	regulation of RNA biosynthetic process
LGL92_12630	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGL92_12635	COG0628	permease
LGL92_12640	COG4783	chaperone-mediated protein folding
LGL92_12645	COG1393	Belongs to the ArsC family
LGL92_12650	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGL92_12655	COG2233	PERMEase
LGL92_12660	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGL92_12665	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGL92_12670	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGL92_12675	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL92_12685	COG0581	inorganic phosphate transmembrane transporter activity
LGL92_12690	COG0573	inorganic phosphate transmembrane transporter activity
LGL92_12695	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGL92_12710	COG2239	Acts as a magnesium transporter
LGL92_12715	COG0443	Heat shock 70 kDa protein
LGL92_12725	COG3121	Chaperone
LGL92_12740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL92_12750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL92_12755	COG0477	Major facilitator Superfamily
LGL92_12760	COG2205	protein histidine kinase activity
LGL92_12765	COG0745	RESPONSE REGULATOR receiver
LGL92_12770	COG3422	double-strand break repair
LGL92_12775	COG0826	peptidase U32
LGL92_12780	COG1597	lipid kinase activity
LGL92_12795	COG0351	phosphomethylpyrimidine kinase
LGL92_12810	COG0519	Catalyzes the synthesis of GMP from XMP
LGL92_12810	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGL92_12815	COG0517	IMP dehydrogenase activity
LGL92_12815	COG0516	GMP reductase activity
LGL92_12820	COG1570	exodeoxyribonuclease VII activity
LGL92_12825	COG1645	bacterial-type flagellum-dependent swarming motility
LGL92_12835	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL92_12840	COG2976	Protein conserved in bacteria
LGL92_12845	COG0124	histidyl-tRNA synthetase
LGL92_12865	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGL92_12880	COG4953	penicillin-binding protein 1C
LGL92_12885	COG2373	Large extracellular alpha-helical protein
LGL92_12900	COG2975	iron-sulfur cluster assembly
LGL92_12905	COG0633	Ferredoxin
LGL92_12910	COG0443	Heat shock 70 kDa protein
LGL92_12925	COG0822	iron-sulfur transferase activity
LGL92_12935	COG1959	2 iron, 2 sulfur cluster binding
LGL92_12940	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LGL92_12950	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL92_12955	COG3683	transport system, periplasmic component
LGL92_12960	COG3711	transcriptional antiterminator
LGL92_12965	COG2814	Major facilitator Superfamily
LGL92_12975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL92_12975	COG1017	nitric oxide dioxygenase activity
LGL92_12980	COG2188	Transcriptional regulator
LGL92_12990	COG3457	Alanine racemase
LGL92_12995	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LGL92_13010	COG0347	Belongs to the P(II) protein family
LGL92_13015	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL92_13015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL92_13020	COG2204	response regulator
LGL92_13025	COG3170	Tfp pilus assembly protein FimV
LGL92_13030	COG2205	protein histidine kinase activity
LGL92_13045	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LGL92_13055	COG0560	Phosphoserine phosphatase
LGL92_13060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL92_13060	COG1263	PTS System
LGL92_13070	COG1737	Transcriptional regulator
LGL92_13075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL92_13085	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGL92_13095	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGL92_13110	COG0481	GTPase activity
LGL92_13115	COG3086	response to oxidative stress
LGL92_13125	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LGL92_13135	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGL92_13145	COG0513	Belongs to the DEAD box helicase family
LGL92_13160	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LGL92_13170	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGL92_13175	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGL92_13180	COG0497	DNA recombination
LGL92_13185	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL92_13195	COG2867	negative regulation of translational initiation
LGL92_13200	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGL92_13230	COG2963	transposase activity
LGL92_13240	COG1069	ribulokinase activity
LGL92_13250	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL92_13255	COG1129	ABC transporter
LGL92_13280	COG1620	l-lactate permease
LGL92_13285	COG1304	FMN binding
LGL92_13290	COG0579	oxidoreductase
LGL92_13295	COG1278	Cold shock
LGL92_13325	COG1780	Probably involved in ribonucleotide reductase function
LGL92_13330	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL92_13340	COG4175	Glycine betaine
LGL92_13345	COG4176	ABC-type proline glycine betaine transport system permease component
LGL92_13350	COG2113	Glycine betaine
LGL92_13365	COG1846	Transcriptional regulator
LGL92_13375	COG1566	PFAM secretion protein HlyD family protein
LGL92_13380	COG2814	Major facilitator Superfamily
LGL92_13385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL92_13390	COG3118	belongs to the thioredoxin family
LGL92_13395	COG3148	PFAM DTW domain containing protein
LGL92_13400	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL92_13400	COG1042	CoA-binding domain protein
LGL92_13400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL92_13405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL92_13410	COG5544	Lipoprotein
LGL92_13435	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL92_13445	COG2011	ABC-type metal ion transport system permease component
LGL92_13450	COG1464	Belongs to the NlpA lipoprotein family
LGL92_13460	COG1720	tRNA m6t6A37 methyltransferase activity
LGL92_13465	COG0442	prolyl-tRNA aminoacylation
LGL92_13470	COG3015	lipoprotein NlpE involved in copper resistance
LGL92_13480	COG4681	YaeQ
LGL92_13490	COG4568	rho-dependent transcription termination
LGL92_13505	COG0346	lactoylglutathione lyase activity
LGL92_13520	COG0825	malonyl-CoA metabolic process
LGL92_13525	COG0587	DNA-directed DNA polymerase activity
LGL92_13530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGL92_13550	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL92_13555	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LGL92_13565	COG0750	zinc metalloprotease
LGL92_13570	COG0575	Belongs to the CDS family
LGL92_13590	COG0528	UMP kinase activity
LGL92_13595	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGL92_13615	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LGL92_13620	COG2171	N-acyltransferase activity
LGL92_13635	COG0564	pseudouridine synthase activity
LGL92_13640	COG3098	single-species biofilm formation
LGL92_13655	COG1611	Belongs to the LOG family
LGL92_13665	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LGL92_13670	COG2363	Small membrane protein
LGL92_13675	COG0583	DNA-binding transcription factor activity
LGL92_13685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGL92_13690	COG2166	iron-sulfur cluster assembly
LGL92_13695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGL92_13700	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LGL92_13715	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL92_13720	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LGL92_13720	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL92_13725	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL92_13730	COG1074	ATP-dependent DNA helicase activity
LGL92_13735	COG1025	Belongs to the peptidase M16 family
LGL92_13740	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGL92_13745	COG4967	type IV pilus modification protein PilV
LGL92_13770	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGL92_13775	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LGL92_13785	COG3066	DNA modification
LGL92_13790	COG0861	Integral membrane protein TerC family
LGL92_13795	COG0667	Aldo Keto reductase
LGL92_13800	COG0477	Major facilitator Superfamily
LGL92_13805	COG0204	Acyl-transferase
LGL92_13805	COG0318	PFAM AMP-dependent synthetase and ligase
LGL92_13815	COG1609	Transcriptional regulator
LGL92_13825	COG0583	DNA-binding transcription factor activity
LGL92_13830	COG0583	DNA-binding transcription factor activity
LGL92_13900	COG2165	general secretion pathway protein
LGL92_13910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL92_13940	COG1127	ABC transporter
LGL92_13945	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL92_13990	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGL92_14000	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGL92_14005	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL92_14010	COG4974	Belongs to the 'phage' integrase family
LGL92_14015	COG0716	FMN binding
LGL92_14025	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGL92_14035	COG1272	protein, Hemolysin III
LGL92_14055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGL92_14060	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL92_14065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL92_14070	COG0006	proline dipeptidase activity
LGL92_14080	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGL92_14090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGL92_14095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL92_14100	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGL92_14115	COG1279	arginine transmembrane transporter activity
LGL92_14125	COG0191	fructose-bisphosphate aldolase activity
LGL92_14130	COG0126	phosphoglycerate kinase activity
LGL92_14135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGL92_14140	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGL92_14150	COG1166	arginine decarboxylase activity
LGL92_14155	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGL92_14170	COG0640	Transcriptional regulator
LGL92_14175	COG3091	SprT-like family
LGL92_14180	COG2356	endonuclease I
LGL92_14185	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGL92_14190	COG0189	ligase activity
LGL92_14195	COG1678	Uncharacterized ACR, COG1678
LGL92_14200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGL92_14205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL92_14215	COG2805	Type II/IV secretion system protein
LGL92_14220	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGL92_14225	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGL92_14230	COG0762	integral membrane protein
LGL92_14235	COG1872	DUF167
LGL92_14240	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGL92_14245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL92_14260	COG3171	Protein conserved in bacteria
LGL92_14270	COG1194	a g-specific adenine glycosylase
LGL92_14275	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LGL92_14280	COG0741	lytic transglycosylase activity
LGL92_14315	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL92_14320	COG1882	Formate acetyltransferase
LGL92_14325	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGL92_14330	COG0814	amino acid
LGL92_14345	COG1028	Short-chain dehydrogenase reductase Sdr
LGL92_14350	COG3433	isochorismatase activity
LGL92_14350	COG1535	isochorismatase
LGL92_14355	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGL92_14360	COG1169	isochorismate synthase
LGL92_14365	COG4592	Periplasmic binding protein
LGL92_14375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL92_14380	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL92_14385	COG1120	ATPase activity
LGL92_14395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGL92_14400	COG3251	PFAM MbtH domain protein
LGL92_14410	COG4774	siderophore transport
LGL92_14415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGL92_14440	COG4964	Belongs to the GSP D family
LGL92_14495	COG0848	biopolymer transport protein
LGL92_14500	COG0811	peptide transport
LGL92_14505	COG0626	cystathionine gamma-synthase activity
LGL92_14510	COG0586	Pfam SNARE associated Golgi protein
LGL92_14515	COG2207	Transcriptional regulator
LGL92_14520	COG1979	alcohol dehydrogenase
LGL92_14525	COG0656	L-ascorbic acid biosynthetic process
LGL92_14535	COG2132	Multicopper oxidase
LGL92_14545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGL92_14550	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL92_14555	COG0583	DNA-binding transcription factor activity
LGL92_14560	COG0187	DNA topoisomerase II activity
LGL92_14565	COG3150	esterase
LGL92_14570	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGL92_14575	COG3151	Protein conserved in bacteria
LGL92_14580	COG0494	nUDIX hydrolase
LGL92_14585	COG1538	Outer membrane efflux protein
LGL92_14590	COG5463	Belongs to the UPF0441 family
LGL92_14595	COG0754	glutathionylspermidine amidase activity
LGL92_14600	COG3384	dioxygenase
LGL92_14605	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGL92_14615	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LGL92_14615	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGL92_14625	COG3025	triphosphatase activity
LGL92_14630	COG4991	sh3 domain protein
LGL92_14635	COG0617	tRNA 3'-terminal CCA addition
LGL92_14640	COG1968	undecaprenyl-diphosphatase activity
LGL92_14645	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGL92_14650	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGL92_14655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGL92_14660	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGL92_14665	COG0358	DNA primase activity
LGL92_14695	COG1028	Short-chain dehydrogenase reductase Sdr
LGL92_14730	COG0463	Glycosyl transferase, family 2
LGL92_14795	COG3210	domain, Protein
LGL92_14800	COG2831	hemolysin activation secretion protein
LGL92_14805	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGL92_14805	COG1902	pentaerythritol trinitrate reductase activity
LGL92_14820	COG1451	nucleotide metabolic process
LGL92_14825	COG0673	inositol 2-dehydrogenase activity
LGL92_14830	COG0861	Integral membrane protein TerC family
LGL92_14835	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LGL92_14845	COG2721	sulfolactate sulfo-lyase activity
LGL92_14860	COG2271	Major facilitator Superfamily
LGL92_14875	COG0586	Pfam SNARE associated Golgi protein
LGL92_14890	COG4575	ribosome binding
LGL92_14895	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LGL92_14905	COG2259	Doxx family
LGL92_14910	COG0583	DNA-binding transcription factor activity
LGL92_14915	COG1741	Belongs to the pirin family
LGL92_14930	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGL92_14945	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL92_14950	COG2823	Periplasmic or secreted lipoprotein
LGL92_14955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL92_14960	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LGL92_14965	COG5002	protein histidine kinase activity
LGL92_14965	COG2198	Histidine kinase
LGL92_14965	COG0784	Response regulator, receiver
LGL92_14975	COG1242	4 iron, 4 sulfur cluster binding
LGL92_14980	COG0069	glutamate synthase activity
LGL92_14980	COG0070	glutamate synthase
LGL92_14980	COG0067	glutamate synthase
LGL92_14985	COG0493	'glutamate synthase
LGL92_14995	COG2969	positive regulation of protein catabolic process
LGL92_15000	COG0625	glutathione transferase activity
LGL92_15005	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGL92_15010	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGL92_15015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGL92_15020	COG3105	Protein conserved in bacteria
LGL92_15025	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL92_15035	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGL92_15040	COG5007	Belongs to the BolA IbaG family
LGL92_15045	COG3113	response to antibiotic
LGL92_15050	COG2854	intermembrane phospholipid transfer
LGL92_15055	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL92_15060	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL92_15065	COG1127	ABC transporter
LGL92_15070	COG0530	calcium, potassium:sodium antiporter activity
LGL92_15075	COG0517	IMP dehydrogenase activity
LGL92_15075	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGL92_15080	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGL92_15085	COG3117	lipopolysaccharide transmembrane transporter activity
LGL92_15090	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGL92_15095	COG1137	ATPase activity
LGL92_15100	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGL92_15120	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL92_15125	COG0540	Belongs to the ATCase OTCase family
LGL92_15130	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LGL92_15140	COG0366	Alpha amylase catalytic
LGL92_15145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL92_15145	COG1263	PTS System
LGL92_15155	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGL92_15165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL92_15170	COG3783	Cytochrome b(562)
LGL92_15175	COG0312	modulator of DNA gyrase
LGL92_15180	COG3028	Belongs to the UPF0307 family
LGL92_15185	COG2732	(Barnase) inhibitor
LGL92_15190	COG4290	ribonuclease
LGL92_15200	COG1289	transmembrane transporter activity
LGL92_15205	COG1566	PFAM secretion protein HlyD family protein
LGL92_15215	COG0583	DNA-binding transcription factor activity
LGL92_15220	COG0312	modulator of DNA gyrase
LGL92_15225	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL92_15230	COG3164	Protein of unknown function
LGL92_15240	COG0424	maF-like protein
LGL92_15245	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGL92_15250	COG1792	Involved in formation and maintenance of cell shape
LGL92_15255	COG1077	Cell shape determining protein MreB Mrl
LGL92_15260	COG2200	EAL domain
LGL92_15260	COG2199	diguanylate cyclase activity
LGL92_15265	COG0604	alcohol dehydrogenase
LGL92_15270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL92_15275	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LGL92_15285	COG0511	ligase activity, forming carbon-carbon bonds
LGL92_15290	COG0439	Biotin carboxylase
LGL92_15295	COG3924	membrane
LGL92_15300	COG4145	pantothenate transmembrane transporter activity
LGL92_15305	COG2264	protein methyltransferase activity
LGL92_15310	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL92_15315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGL92_15325	COG1560	Kdo2-lipid A biosynthetic process
LGL92_15335	COG1346	cytolysis
LGL92_15340	COG1380	Effector of murein hydrolase LrgA
LGL92_15345	COG0583	DNA-binding transcription factor activity
LGL92_15350	COG0025	NhaP-type Na H and K H
LGL92_15355	COG2252	PERMEase
LGL92_15370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGL92_15375	COG2315	Protein conserved in bacteria
LGL92_15380	COG1448	Aminotransferase
LGL92_15395	COG0604	alcohol dehydrogenase
LGL92_15405	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL92_15410	COG0735	belongs to the Fur family
LGL92_15415	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGL92_15420	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGL92_15425	COG2937	Belongs to the GPAT DAPAT family
LGL92_15445	COG4580	involved in the transport of maltose and maltodextrins
LGL92_15460	COG2182	Extracellular solute-binding protein
LGL92_15465	COG1175	transmembrane transport
LGL92_15470	COG3833	ABC-type maltose transport systems, permease component
LGL92_15475	COG3223	Belongs to the PsiE family
LGL92_15485	COG0527	aspartate kinase activity
LGL92_15500	COG3328	transposase activity
LGL92_15515	COG3328	transposase activity
LGL92_15550	COG1222	aaa ATPase
LGL92_15635	COG0583	DNA-binding transcription factor activity
LGL92_15670	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGL92_15710	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LGL92_15715	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGL92_15720	COG1739	Uncharacterized protein family UPF0029
LGL92_15730	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL92_15730	COG1024	Enoyl-CoA hydratase
LGL92_15740	COG0543	2 iron, 2 sulfur cluster binding
LGL92_15755	COG0250	Participates in transcription elongation, termination and antitermination
LGL92_15770	COG0805	protein transport
LGL92_15775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL92_15780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL92_15785	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGL92_15790	COG3165	ubiquinone biosynthetic process from chorismate
LGL92_15795	COG2226	methyltransferase
LGL92_15800	COG1322	Protein conserved in bacteria
LGL92_15805	COG0586	Pfam SNARE associated Golgi protein
LGL92_15810	COG1966	Carbon starvation protein
LGL92_15825	COG0412	Dienelactone hydrolase
LGL92_15830	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGL92_15835	COG0583	DNA-binding transcription factor activity
LGL92_15840	COG0697	spore germination
LGL92_15850	COG0584	glycerophosphoryl diester phosphodiesterase
LGL92_15860	COG0395	ABC-type sugar transport system, permease component
LGL92_15865	COG1175	transmembrane transport
LGL92_15870	COG1653	transport
LGL92_15905	COG0410	ABC transporter
LGL92_15915	COG4177	L-phenylalanine transmembrane transporter activity
LGL92_15935	COG1929	Belongs to the glycerate kinase type-1 family
LGL92_15940	COG2610	gluconate transmembrane transporter activity
LGL92_15945	COG3835	regulator
LGL92_15955	COG2177	Part of the ABC transporter FtsEX involved in
LGL92_15960	COG2884	Cell division ATP-binding protein ftsE
LGL92_15965	COG0552	protein localization to endoplasmic reticulum
LGL92_15965	COG0552	protein localization to endoplasmic reticulum
LGL92_15970	COG0742	ribosomal rna small subunit methyltransferase
LGL92_15975	COG3776	membrane
LGL92_15990	COG3714	YhhN family
LGL92_16005	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGL92_16015	COG0247	lactate metabolic process
LGL92_16025	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL92_16035	COG2271	Major facilitator Superfamily
LGL92_16040	COG0584	glycerophosphoryl diester phosphodiesterase
LGL92_16045	COG0561	phosphatase activity
LGL92_16050	COG2267	carboxylic ester hydrolase activity
LGL92_16055	COG1280	lysine exporter protein (LysE YggA)
LGL92_16060	COG0514	ATP-dependent DNA helicase (RecQ)
LGL92_16065	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LGL92_16070	COG2050	protein possibly involved in aromatic compounds catabolism
LGL92_16090	COG5564	TIM-barrel signal transduction protein
LGL92_16095	COG5441	Belongs to the UPF0261 family
LGL92_16105	COG0210	DNA helicase
LGL92_16110	COG1011	Hydrolase
LGL92_16115	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL92_16120	COG3159	Protein conserved in bacteria
LGL92_16125	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGL92_16130	COG5567	small periplasmic lipoprotein
LGL92_16140	COG3072	Adenylate cyclase
LGL92_16145	COG0181	hydroxymethylbilane synthase activity
LGL92_16150	COG1587	Uroporphyrinogen-III synthase
LGL92_16155	COG2959	enzyme of heme biosynthesis
LGL92_16160	COG3071	HemY protein
LGL92_16210	COG2244	polysaccharide biosynthetic process
LGL92_16215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL92_16220	COG0456	acetyltransferase
LGL92_16225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGL92_16230	COG1088	dTDP-glucose 4,6-dehydratase activity
LGL92_16235	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGL92_16240	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL92_16245	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL92_16250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGL92_16255	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGL92_16260	COG3118	belongs to the thioredoxin family
LGL92_16270	COG0248	Ppx GppA phosphatase
LGL92_16280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL92_16295	COG3397	chitin binding
LGL92_16305	COG0129	dihydroxy-acid dehydratase activity
LGL92_16315	COG3978	acetolactate synthase activity
LGL92_16335	COG3085	chromosome segregation
LGL92_16340	COG0583	DNA-binding transcription factor activity
LGL92_16420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL92_16430	COG0678	peroxiredoxin activity
LGL92_16430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL92_16435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL92_16470	COG1629	transport
LGL92_16475	COG0165	Argininosuccinate lyase
LGL92_16480	COG0137	argininosuccinate synthase activity
LGL92_16485	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL92_16530	COG0527	aspartate kinase activity
LGL92_16530	COG0460	homoserine dehydrogenase
LGL92_16535	COG0626	cystathionine gamma-synthase activity
LGL92_16540	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LGL92_16550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGL92_16555	COG1609	Transcriptional regulator
LGL92_16560	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL92_16565	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGL92_16570	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGL92_16575	COG1575	Belongs to the MenA family. Type 1 subfamily
LGL92_16580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGL92_16585	COG3074	FtsZ-dependent cytokinesis
LGL92_16590	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGL92_16595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGL92_16600	COG1494	fructose-1,6-bisphosphatase
LGL92_16605	COG2814	Major facilitator Superfamily
LGL92_16615	COG3152	Membrane
LGL92_16630	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGL92_16640	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL92_16645	COG3678	ATP-independent chaperone mediated protein folding
LGL92_16650	COG0745	RESPONSE REGULATOR receiver
LGL92_16655	COG2205	protein histidine kinase activity
LGL92_16660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGL92_16665	COG1045	serine acetyltransferase
LGL92_16670	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGL92_16675	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LGL92_16680	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL92_16685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGL92_16690	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGL92_16695	COG4942	peptidase
LGL92_16700	COG2861	carbohydrate metabolic process
LGL92_16715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL92_16720	COG0859	PFAM glycosyl transferase family 9
LGL92_16725	COG0859	PFAM glycosyl transferase family 9
LGL92_16730	COG1519	Transferase
LGL92_16750	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGL92_16755	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGL92_16760	COG2003	Belongs to the UPF0758 family
LGL92_16765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGL92_16770	COG0756	dUTP diphosphatase activity
LGL92_16775	COG1309	transcriptional regulator
LGL92_16780	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGL92_16785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGL92_16790	COG1561	YicC-like family, N-terminal region
LGL92_16805	COG5001	Diguanylate cyclase
LGL92_16810	COG1024	Enoyl-CoA hydratase
LGL92_16815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL92_16830	COG2860	membrane
LGL92_16835	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL92_16845	COG1758	RNA polymerase activity
LGL92_16850	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL92_16855	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL92_16860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGL92_16865	COG0786	glutamate:sodium symporter activity
LGL92_16870	COG2233	PERMEase
LGL92_16875	COG2982	Protein involved in outer membrane biogenesis
LGL92_16880	COG0456	acetyltransferase
LGL92_16895	COG1011	Hydrolase
LGL92_16910	COG3852	Histidine kinase
LGL92_16920	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL92_16930	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGL92_16935	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL92_16935	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL92_16940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL92_16945	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGL92_16950	COG3084	Protein conserved in bacteria
LGL92_16960	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGL92_16985	COG0138	bifunctional purine biosynthesis protein purh
LGL92_16990	COG0151	Belongs to the GarS family
LGL92_17010	COG1515	deoxyribonuclease V activity
LGL92_17015	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGL92_17020	COG2816	NAD+ diphosphatase activity
LGL92_17025	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LGL92_17040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL92_17045	COG2104	thiamine diphosphate biosynthetic process
LGL92_17050	COG2022	thiamine diphosphate biosynthetic process
LGL92_17060	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGL92_17065	COG0085	RNA polymerase activity
LGL92_17070	COG0222	ribosome binding
LGL92_17075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGL92_17085	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGL92_17090	COG0250	Participates in transcription elongation, termination and antitermination
LGL92_17135	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGL92_17160	COG2186	Transcriptional regulator
LGL92_17165	COG1609	Transcriptional regulator
LGL92_17170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL92_17180	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL92_17185	COG1129	ABC transporter
LGL92_17190	COG1869	D-ribose catabolic process
LGL92_17195	COG3158	transport of potassium into the cell
LGL92_17200	COG0714	Associated with various cellular activities
LGL92_17205	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LGL92_17215	COG2502	aspartate--ammonia ligase
LGL92_17220	COG1522	sequence-specific DNA binding
LGL92_17225	COG0716	FMN binding
LGL92_17230	COG0445	tRNA wobble uridine modification
LGL92_17235	COG0357	Ribosomal RNA small subunit methyltransferase G
LGL92_17240	COG3312	ion transport
LGL92_17245	COG0356	it plays a direct role in the translocation of protons across the membrane
LGL92_17255	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGL92_17265	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGL92_17270	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGL92_17280	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGL92_17295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGL92_17300	COG0573	inorganic phosphate transmembrane transporter activity
LGL92_17305	COG0581	inorganic phosphate transmembrane transporter activity
LGL92_17315	COG0704	Plays a role in the regulation of phosphate uptake
LGL92_17320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL92_17325	COG0765	amino acid transport
LGL92_17330	COG0765	amino acid transport
LGL92_17335	COG2252	PERMEase
LGL92_17340	COG0840	transmembrane signaling receptor activity
LGL92_17350	COG3121	Chaperone
LGL92_17365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGL92_17370	COG0706	membrane insertase activity
LGL92_17380	COG0594	ribonuclease P activity
LGL92_17385	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LGL92_17395	COG2944	sequence-specific DNA binding
LGL92_17560	COG0741	lytic transglycosylase activity
LGL92_17575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL92_17695	COG1196	nuclear chromosome segregation
