locus-tag	class	description
LGL91_00010	COG0592	DNA-directed DNA polymerase activity
LGL91_00020	COG0187	DNA topoisomerase II activity
LGL91_00025	COG0561	phosphatase activity
LGL91_00030	COG0823	Involved in the tonB-independent uptake of proteins
LGL91_00035	COG5645	(Lipo)protein
LGL91_00050	COG0569	domain protein
LGL91_00050	COG2985	domain, Protein
LGL91_00055	COG3977	Valine--pyruvate aminotransferase
LGL91_00060	COG2885	chlorophyll binding
LGL91_00085	COG2818	Glycosylase
LGL91_00135	COG2213	PTS system mannitol-specific
LGL91_00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_00145	COG3722	fumarate hydratase activity
LGL91_00155	COG2258	MOSC domain
LGL91_00160	COG0840	transmembrane signaling receptor activity
LGL91_00165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL91_00180	COG0437	4 iron, 4 sulfur cluster binding
LGL91_00185	COG2864	formate dehydrogenase
LGL91_00195	COG1921	L-seryl-tRNASec selenium transferase activity
LGL91_00200	COG3276	selenocysteine insertion sequence binding
LGL91_00205	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LGL91_00215	COG3274	enterobacterial common antigen metabolic process
LGL91_00225	COG0582	viral genome integration into host DNA
LGL91_00265	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGL91_00270	COG2986	histidine ammonia-lyase
LGL91_00290	COG2194	sulfuric ester hydrolase activity
LGL91_00295	COG2197	response regulator
LGL91_00300	COG3851	Histidine kinase
LGL91_00305	COG2271	Major facilitator Superfamily
LGL91_00315	COG0747	negative chemotaxis
LGL91_00320	COG0601	transmembrane transport
LGL91_00325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL91_00330	COG0444	Belongs to the ABC transporter superfamily
LGL91_00335	COG4608	Belongs to the ABC transporter superfamily
LGL91_00340	COG2194	sulfuric ester hydrolase activity
LGL91_00365	COG1215	transferase activity, transferring glycosyl groups
LGL91_00370	COG1215	transferase activity, transferring glycosyl groups
LGL91_00375	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGL91_00380	COG0457	Tetratricopeptide repeat
LGL91_00380	COG3118	belongs to the thioredoxin family
LGL91_00385	COG2200	EAL domain
LGL91_00385	COG2199	diguanylate cyclase activity
LGL91_00390	COG1301	dicarboxylic acid transport
LGL91_00395	COG0612	Peptidase, M16
LGL91_00400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL91_00405	COG1942	4-Oxalocrotonate Tautomerase
LGL91_00410	COG2200	EAL domain
LGL91_00420	COG1295	ribonuclease BN
LGL91_00430	COG1301	dicarboxylic acid transport
LGL91_00435	COG0626	cystathionine gamma-synthase activity
LGL91_00450	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL91_00455	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGL91_00460	COG0339	signal peptide processing
LGL91_00465	COG0742	ribosomal rna small subunit methyltransferase
LGL91_00475	COG0589	response to stress
LGL91_00485	COG0306	phosphate transporter
LGL91_00490	COG2081	HI0933 family
LGL91_00500	COG1247	-acetyltransferase
LGL91_00505	COG1741	Belongs to the pirin family
LGL91_00510	COG1609	Transcriptional regulator
LGL91_00515	COG2610	gluconate transmembrane transporter activity
LGL91_00520	COG3265	gluconokinase activity
LGL91_00525	COG2095	MarC family integral membrane protein
LGL91_00530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL91_00535	COG3275	phosphorelay sensor kinase activity
LGL91_00540	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGL91_00545	COG1523	belongs to the glycosyl hydrolase 13 family
LGL91_00550	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGL91_00555	COG0297	glycogen (starch) synthase activity
LGL91_00560	COG0058	SHG alpha-glucan phosphorylase activity
LGL91_00565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL91_00570	COG1349	DNA-binding transcription factor activity
LGL91_00575	COG0705	Rhomboid family
LGL91_00585	COG2909	trisaccharide binding
LGL91_00590	COG0058	SHG alpha-glucan phosphorylase activity
LGL91_00595	COG1640	4-alpha-glucanotransferase
LGL91_00605	COG1040	competence protein
LGL91_00610	COG0596	Alpha beta hydrolase
LGL91_00630	COG1918	ferrous iron import across plasma membrane
LGL91_00635	COG2183	response to ionizing radiation
LGL91_00660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL91_00675	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGL91_00685	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGL91_00690	COG1011	Hydrolase
LGL91_00700	COG0494	nUDIX hydrolase
LGL91_00705	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL91_00730	COG4796	Type ii and iii secretion system protein
LGL91_00735	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL91_00755	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGL91_00765	COG0180	Tryptophanyl-tRNA synthetase
LGL91_00785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGL91_00790	COG0402	S-adenosylhomocysteine deaminase activity
LGL91_00795	COG0738	Major facilitator superfamily
LGL91_00810	COG1609	Transcriptional regulator
LGL91_00815	COG1486	melibiose metabolic process
LGL91_00820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL91_00835	COG1289	transmembrane transporter activity
LGL91_00840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL91_00845	COG1765	OsmC-like protein
LGL91_00870	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL91_00875	COG3954	Phosphoribulokinase
LGL91_00885	COG0429	hydrolase of the alpha beta-hydrolase fold
LGL91_00895	COG0859	PFAM glycosyl transferase family 9
LGL91_00900	COG1216	Glycosyl transferase, family 2
LGL91_00905	COG0488	(ABC) transporter
LGL91_00910	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL91_00920	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGL91_00925	COG1047	Peptidyl-prolyl cis-trans
LGL91_00935	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL91_00940	COG2964	Protein conserved in bacteria
LGL91_00950	COG2923	Belongs to the DsrF TusC family
LGL91_00955	COG2168	tRNA wobble position uridine thiolation
LGL91_00960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGL91_00965	COG0049	tRNA binding
LGL91_00975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGL91_00990	COG0051	transcription antitermination factor activity, RNA binding
LGL91_00995	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGL91_01005	COG0089	rRNA binding
LGL91_01010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGL91_01015	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGL91_01020	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGL91_01030	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGL91_01035	COG0255	Belongs to the universal ribosomal protein uL29 family
LGL91_01040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGL91_01045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGL91_01055	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGL91_01080	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGL91_01085	COG1841	ribosomal large subunit assembly
LGL91_01090	COG0200	Binds to the 23S rRNA
LGL91_01095	COG0201	protein transport
LGL91_01100	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL91_01105	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGL91_01115	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGL91_01125	COG0203	ribosomal protein L17
LGL91_01130	COG0789	Transcriptional regulator
LGL91_01135	COG3036	rescue of stalled ribosome
LGL91_01140	COG1970	mechanosensitive ion channel activity
LGL91_01150	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGL91_01150	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGL91_01155	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGL91_01160	COG0242	peptide deformylase activity
LGL91_01165	COG0758	DNA mediated transformation
LGL91_01170	COG2922	Belongs to the Smg family
LGL91_01175	COG0551	DNA topoisomerase type I activity
LGL91_01180	COG0009	L-threonylcarbamoyladenylate synthase
LGL91_01190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGL91_01215	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGL91_01260	COG0250	Participates in transcription elongation, termination and antitermination
LGL91_01265	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGL91_01275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGL91_01280	COG0222	ribosome binding
LGL91_01285	COG0085	RNA polymerase activity
LGL91_01290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGL91_01300	COG2022	thiamine diphosphate biosynthetic process
LGL91_01305	COG2104	thiamine diphosphate biosynthetic process
LGL91_01310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL91_01325	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LGL91_01330	COG2816	NAD+ diphosphatase activity
LGL91_01335	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGL91_01340	COG1515	deoxyribonuclease V activity
LGL91_01360	COG0151	Belongs to the GarS family
LGL91_01365	COG0138	bifunctional purine biosynthesis protein purh
LGL91_01400	COG3162	membrane
LGL91_01405	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGL91_01410	COG1301	dicarboxylic acid transport
LGL91_01420	COG1309	transcriptional regulator
LGL91_01425	COG4232	protein-disulfide reductase activity
LGL91_01435	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL91_01465	COG1509	lysine 2,3-aminomutase activity
LGL91_01495	COG3188	usher protein
LGL91_01515	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL91_01520	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL91_01525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL91_01530	COG1053	succinate dehydrogenase
LGL91_01535	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGL91_01540	COG3264	Mechanosensitive ion channel
LGL91_01540	COG1511	domain protein
LGL91_01545	COG0688	phosphatidylethanolamine metabolic process
LGL91_01550	COG1162	GTPase activity
LGL91_01555	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGL91_01575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGL91_01580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGL91_01580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGL91_01585	COG0802	atpase or kinase
LGL91_01590	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL91_01600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGL91_01610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGL91_01615	COG0330	HflC and HflK could
LGL91_01620	COG0330	HflC and HflK could
LGL91_01625	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LGL91_01630	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGL91_01635	COG1959	2 iron, 2 sulfur cluster binding
LGL91_01640	COG0557	exoribonuclease II activity
LGL91_01645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL91_01665	COG3121	Chaperone
LGL91_01670	COG3188	usher protein
LGL91_01690	COG1073	alpha beta
LGL91_01700	COG0360	Binds together with S18 to 16S ribosomal RNA
LGL91_01705	COG2965	DNA replication, synthesis of RNA primer
LGL91_01710	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGL91_01715	COG0359	binds to the 23S rRNA
LGL91_01720	COG3061	Opacity-associated protein A
LGL91_01725	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL91_01735	COG0737	Belongs to the 5'-nucleotidase family
LGL91_01740	COG1218	3'(2'),5'-bisphosphate nucleotidase
LGL91_01745	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LGL91_01755	COG1253	flavin adenine dinucleotide binding
LGL91_01760	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL91_01765	COG0729	surface antigen
LGL91_01770	COG2911	Protein conserved in bacteria
LGL91_01775	COG2105	PFAM AIG2 family protein
LGL91_01780	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGL91_01790	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL91_01805	COG3423	Transcriptional regulator
LGL91_01820	COG0142	geranyltranstransferase activity
LGL91_01835	COG0697	spore germination
LGL91_01840	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGL91_01845	COG0642	Histidine kinase
LGL91_01850	COG0745	RESPONSE REGULATOR receiver
LGL91_01855	COG2027	D-alanyl-D-alanine carboxypeptidase
LGL91_01865	COG1534	Rna-binding protein
LGL91_01870	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LGL91_01880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGL91_01885	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGL91_01890	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGL91_01910	COG0195	Participates in both transcription termination and antitermination
LGL91_01920	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGL91_01935	COG1185	polyribonucleotide nucleotidyltransferase activity
LGL91_01950	COG0513	Belongs to the DEAD box helicase family
LGL91_01955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGL91_01960	COG0814	amino acid
LGL91_01970	COG0826	peptidase U32
LGL91_01975	COG0826	peptidase U32
LGL91_01980	COG3154	lipid carrier protein
LGL91_01985	COG3153	acetyltransferase
LGL91_01990	COG2827	Endonuclease containing a URI domain
LGL91_01995	COG0531	amino acid
LGL91_02000	COG1982	Orn Lys Arg decarboxylase major
LGL91_02010	COG3787	Belongs to the UPF0306 family
LGL91_02015	COG0702	epimerase
LGL91_02020	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGL91_02025	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LGL91_02030	COG3454	Phosphonate metabolism
LGL91_02035	COG4778	phosphonate C-P lyase system protein PhnL
LGL91_02040	COG4107	phosphonate C-P lyase system protein PhnK
LGL91_02045	COG3627	carbon phosphorus lyase activity
LGL91_02050	COG3626	phosphonate metabolism
LGL91_02055	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LGL91_02060	COG3624	Phosphonate C-P lyase system protein PhnG
LGL91_02080	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LGL91_02095	COG2927	DNA polymerase III (CHI subunit)
LGL91_02100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGL91_02105	COG0795	lipopolysaccharide-transporting ATPase activity
LGL91_02110	COG0795	lipopolysaccharide-transporting ATPase activity
LGL91_02135	COG3077	Addiction module antitoxin, RelB DinJ family
LGL91_02225	COG5492	domain, Protein
LGL91_02245	COG3119	arylsulfatase activity
LGL91_02250	COG1349	DNA-binding transcription factor activity
LGL91_02260	COG2222	sugar isomerase
LGL91_02265	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_02270	COG3715	PTS system
LGL91_02275	COG3716	PTS system mannose fructose sorbose family IID component
LGL91_02285	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL91_02295	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_02305	COG0641	radical SAM
LGL91_02310	COG3119	arylsulfatase activity
LGL91_02335	COG0859	PFAM glycosyl transferase family 9
LGL91_02350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL91_02355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL91_02365	COG2376	Dihydroxyacetone kinase
LGL91_02370	COG1461	Dihydroxyacetone kinase
LGL91_02375	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LGL91_02375	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_02375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL91_02415	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LGL91_02430	COG2823	Periplasmic or secreted lipoprotein
LGL91_02440	COG4667	esterase of the alpha-beta hydrolase superfamily
LGL91_02445	COG0084	hydrolase, TatD family'
LGL91_02450	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL91_02465	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGL91_02475	COG3726	membrane protein affecting hemolysin expression
LGL91_02480	COG0560	Phosphoserine phosphatase
LGL91_02495	COG0488	(ABC) transporter
LGL91_02520	COG0741	lytic transglycosylase activity
LGL91_02525	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LGL91_02530	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGL91_02535	COG0406	alpha-ribazole phosphatase activity
LGL91_02540	COG3708	Transcriptional regulator
LGL91_02540	COG2207	Transcriptional regulator
LGL91_02545	COG3045	CreA protein
LGL91_02550	COG0745	RESPONSE REGULATOR receiver
LGL91_02585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL91_02590	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGL91_02595	COG0477	Major facilitator Superfamily
LGL91_02605	COG1584	GPR1 FUN34 yaaH family protein
LGL91_02610	COG0443	Heat shock 70 kDa protein
LGL91_02620	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL91_02625	COG0583	DNA-binding transcription factor activity
LGL91_02635	COG0196	riboflavin kinase activity
LGL91_02645	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGL91_02650	COG1047	Peptidyl-prolyl cis-trans
LGL91_02655	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGL91_02670	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGL91_02680	COG2966	Psort location CytoplasmicMembrane, score
LGL91_02705	COG2967	ApaG domain
LGL91_02710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGL91_02715	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LGL91_02725	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LGL91_02735	COG0564	pseudouridine synthase activity
LGL91_02740	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGL91_02745	COG0417	DNA replication proofreading
LGL91_02750	COG0586	Pfam SNARE associated Golgi protein
LGL91_02760	COG1178	ABC-type Fe3 transport system permease component
LGL91_02765	COG4143	(ABC) transporter
LGL91_02780	COG2814	Major facilitator Superfamily
LGL91_02790	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL91_02795	COG0473	3-isopropylmalate dehydrogenase activity
LGL91_02810	COG1022	Amp-dependent synthetase and ligase
LGL91_02815	COG0028	Belongs to the TPP enzyme family
LGL91_02840	COG0275	rRNA processing
LGL91_02845	COG3116	cell division
LGL91_02850	COG0768	penicillin binding
LGL91_02855	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGL91_02860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGL91_02875	COG0772	Belongs to the SEDS family
LGL91_02880	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGL91_02885	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL91_02900	COG0849	cell division
LGL91_02905	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGL91_02930	COG0494	nUDIX hydrolase
LGL91_02950	COG0516	GMP reductase activity
LGL91_02955	COG1459	type II secretion system
LGL91_02960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL91_02965	COG4969	Belongs to the N-Me-Phe pilin family
LGL91_02980	COG3725	Membrane protein required for beta-lactamase induction
LGL91_02995	COG4932	domain protein
LGL91_02995	COG2373	Large extracellular alpha-helical protein
LGL91_02995	COG1388	LysM domain
LGL91_03000	COG1113	amino acid transport
LGL91_03005	COG2186	Transcriptional regulator
LGL91_03010	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LGL91_03015	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL91_03020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL91_03030	COG1049	propionate catabolic process, 2-methylcitrate cycle
LGL91_03035	COG3112	Uncharacterised protein family (UPF0231)
LGL91_03050	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGL91_03060	COG2132	Multicopper oxidase
LGL91_03070	COG0288	reversible hydration of carbon dioxide
LGL91_03075	COG1131	(ABC) transporter
LGL91_03080	COG0842	Transport permease protein
LGL91_03085	COG0726	polysaccharide deacetylase
LGL91_03090	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGL91_03095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGL91_03100	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGL91_03105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGL91_03110	COG0617	tRNA 3'-terminal CCA addition
LGL91_03125	COG1489	DNA binding
LGL91_03130	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGL91_03140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL91_03145	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGL91_03155	COG0316	Belongs to the HesB IscA family
LGL91_03160	COG2860	membrane
LGL91_03170	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL91_03175	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL91_03180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL91_03190	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL91_03195	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL91_03200	COG3956	TIGRFAM MazG family protein
LGL91_03205	COG0504	CTP synthase activity
LGL91_03215	COG0602	queuosine metabolic process
LGL91_03220	COG0720	synthase
LGL91_03225	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGL91_03235	COG0175	sulfate reduction
LGL91_03250	COG2234	aminopeptidase activity
LGL91_03255	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGL91_03255	COG1648	precorrin-2 dehydrogenase activity
LGL91_03260	COG0175	sulfate reduction
LGL91_03265	COG2895	sulfate adenylyltransferase (ATP) activity
LGL91_03270	COG0529	Catalyzes the synthesis of activated sulfate
LGL91_03280	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGL91_03290	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGL91_03295	COG0585	pseudouridine synthase activity
LGL91_03300	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGL91_03310	COG1388	LysM domain
LGL91_03310	COG4942	peptidase
LGL91_03315	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGL91_03320	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGL91_03330	COG2205	protein histidine kinase activity
LGL91_03330	COG0784	Response regulator, receiver
LGL91_03350	COG0741	lytic transglycosylase activity
LGL91_03470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL91_03490	COG3397	chitin binding
LGL91_03500	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGL91_03545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL91_03555	COG3031	protein transport across the cell outer membrane
LGL91_03585	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL91_03585	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL91_03600	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGL91_03605	COG2137	regulation of response to DNA damage stimulus
LGL91_03610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGL91_03615	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGL91_03650	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL91_03655	COG1238	metal cluster binding
LGL91_03660	COG2918	glutathione biosynthetic process
LGL91_03665	COG1854	S-ribosylhomocysteine lyase activity
LGL91_03670	COG4536	flavin adenine dinucleotide binding
LGL91_03675	COG4137	Cytochrome C assembly protein
LGL91_03680	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGL91_03690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGL91_03695	COG0336	Belongs to the RNA methyltransferase TrmD family
LGL91_03700	COG0335	large ribosomal subunit rRNA binding
LGL91_03705	COG3137	Salt-induced outer membrane protein
LGL91_03710	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL91_03715	COG3279	Response regulator of the LytR AlgR family
LGL91_03720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL91_03725	COG1605	Chorismate mutase
LGL91_03725	COG0287	Prephenate dehydrogenase
LGL91_03730	COG1605	Chorismate mutase
LGL91_03730	COG0077	Prephenate dehydratase
LGL91_03735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGL91_03740	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL91_03745	COG0564	pseudouridine synthase activity
LGL91_03750	COG1496	oxidoreductase activity
LGL91_03755	COG0542	response to heat
LGL91_03785	COG3021	interspecies interaction between organisms
LGL91_03790	COG1388	LysM domain
LGL91_03790	COG0741	lytic transglycosylase activity
LGL91_03800	COG2226	methyltransferase
LGL91_03810	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL91_03820	COG1960	acyl-CoA dehydrogenase activity
LGL91_03825	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL91_03830	COG0121	glutamine amidotransferase
LGL91_03835	COG3034	peptidoglycan biosynthetic process
LGL91_03845	COG1805	sodium ion transport
LGL91_03850	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL91_03855	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL91_03860	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL91_03870	COG1477	protein flavinylation
LGL91_03875	COG2991	Protein conserved in bacteria
LGL91_03895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL91_03900	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGL91_03905	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LGL91_03910	COG1073	alpha beta
LGL91_03925	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGL91_03960	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL91_03980	COG4126	flavin adenine dinucleotide binding
LGL91_03990	COG2974	May be involved in recombination
LGL91_03995	COG1940	carbohydrate kinase activity
LGL91_04000	COG0419	ATPase involved in DNA repair
LGL91_04005	COG0420	3'-5' exonuclease activity
LGL91_04010	COG0745	RESPONSE REGULATOR receiver
LGL91_04015	COG5002	protein histidine kinase activity
LGL91_04025	COG1114	Component of the transport system for branched-chain amino acids
LGL91_04030	COG1113	amino acid transport
LGL91_04035	COG0366	Alpha amylase catalytic
LGL91_04040	COG0300	oxidoreductase activity
LGL91_04045	COG0450	alkyl hydroperoxide reductase
LGL91_04050	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LGL91_04065	COG1862	Preprotein translocase
LGL91_04070	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL91_04075	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL91_04080	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGL91_04085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL91_04085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL91_04090	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGL91_04100	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGL91_04105	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGL91_04110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGL91_04115	COG0142	geranyltranstransferase activity
LGL91_04150	COG0693	protein deglycase activity
LGL91_04155	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGL91_04160	COG1666	GTP binding
LGL91_04165	COG2814	Major facilitator Superfamily
LGL91_04175	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGL91_04180	COG1845	cytochrome c oxidase, subunit III
LGL91_04185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGL91_04190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGL91_04200	COG2223	nitrite transmembrane transporter activity
LGL91_04205	COG3056	Lipoprotein
LGL91_04210	COG0271	Belongs to the BolA IbaG family
LGL91_04220	COG0740	serine-type endopeptidase activity
LGL91_04225	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGL91_04230	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL91_04235	COG0776	regulation of translation
LGL91_04240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL91_04245	COG1555	photosystem II stabilization
LGL91_04250	COG0824	Thioesterase
LGL91_04255	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGL91_04260	COG4533	DNA binding
LGL91_04275	COG1522	sequence-specific DNA binding
LGL91_04280	COG1132	(ABC) transporter
LGL91_04285	COG1132	(ABC) transporter
LGL91_04290	COG0347	Belongs to the P(II) protein family
LGL91_04295	COG0004	ammonium transporteR
LGL91_04300	COG1946	Acyl-CoA thioesterase
LGL91_04305	COG3695	enzyme binding
LGL91_04330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL91_04335	COG0254	rRNA binding
LGL91_04340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL91_04345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL91_04350	COG1309	transcriptional regulator
LGL91_04355	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGL91_04360	COG3264	Mechanosensitive ion channel
LGL91_04360	COG1196	nuclear chromosome segregation
LGL91_04375	COG2832	Protein of unknown function (DUF454)
LGL91_04380	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGL91_04420	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGL91_04425	COG0326	Molecular chaperone. Has ATPase activity
LGL91_04435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LGL91_04440	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL91_04440	COG0543	2 iron, 2 sulfur cluster binding
LGL91_04460	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL91_04505	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL91_04510	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL91_04520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL91_04525	COG4651	solute:proton antiporter activity
LGL91_04525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL91_04530	COG0737	Belongs to the 5'-nucleotidase family
LGL91_04535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGL91_04540	COG3735	TraB family
LGL91_04545	COG2217	Heavy metal translocating P-type atpase
LGL91_04550	COG0789	Transcriptional regulator
LGL91_04555	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGL91_04560	COG0330	HflC and HflK could
LGL91_04565	COG3118	belongs to the thioredoxin family
LGL91_04570	COG0300	oxidoreductase activity
LGL91_04575	COG2755	lipolytic protein G-D-S-L family
LGL91_04580	COG4181	ATPase activity
LGL91_04585	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGL91_04590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGL91_04595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGL91_04600	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL91_04605	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL91_04635	COG3121	Chaperone
LGL91_04665	COG2501	S4 domain
LGL91_04670	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGL91_04685	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGL91_04690	COG1393	Belongs to the ArsC family
LGL91_04700	COG1022	Amp-dependent synthetase and ligase
LGL91_04755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGL91_04765	COG1215	transferase activity, transferring glycosyl groups
LGL91_04785	COG3250	beta-galactosidase activity
LGL91_04800	COG1309	transcriptional regulator
LGL91_04830	COG2197	response regulator
LGL91_04835	COG1278	Cold shock
LGL91_04855	COG3706	GGDEF domain
LGL91_04865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGL91_04875	COG2921	Belongs to the UPF0250 family
LGL91_04880	COG1686	Belongs to the peptidase S11 family
LGL91_04885	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL91_04890	COG0772	Belongs to the SEDS family
LGL91_04895	COG0768	penicillin binding
LGL91_04900	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGL91_04905	COG0799	negative regulation of ribosome biogenesis
LGL91_04910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGL91_04915	COG1466	dna polymerase III delta subunit
LGL91_04920	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LGL91_04930	COG2888	peptidyl-tyrosine sulfation
LGL91_04935	COG1126	abc transporter atp-binding protein
LGL91_04940	COG0765	amino acid transport
LGL91_04945	COG0765	amino acid transport
LGL91_04955	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGL91_04960	COG4535	Mg2 and Co2 transporter CorC
LGL91_04965	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGL91_04970	COG1702	phosphate starvation-inducible protein PhoH
LGL91_04975	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGL91_04980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL91_05015	COG0367	asparagine synthase
LGL91_05020	COG0647	UMP catabolic process
LGL91_05025	COG1940	carbohydrate kinase activity
LGL91_05025	COG1846	Transcriptional regulator
LGL91_05030	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL91_05040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_05040	COG1263	PTS System
LGL91_05040	COG2190	(PTS) system
LGL91_05065	COG0735	belongs to the Fur family
LGL91_05075	COG0840	transmembrane signaling receptor activity
LGL91_05085	COG0596	Alpha beta hydrolase
LGL91_05090	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LGL91_05095	COG0033	Phosphoglucomutase
LGL91_05105	COG0745	RESPONSE REGULATOR receiver
LGL91_05110	COG2205	protein histidine kinase activity
LGL91_05115	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LGL91_05120	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGL91_05140	COG3272	Protein of unknown function (DUF1722)
LGL91_05145	COG0415	Belongs to the DNA photolyase family
LGL91_05150	COG5212	phosphodiesterase
LGL91_05155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGL91_05160	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGL91_05165	COG1984	allophanate hydrolase subunit 2
LGL91_05170	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGL91_05205	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGL91_05210	COG1053	succinate dehydrogenase
LGL91_05215	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL91_05220	COG0567	Dehydrogenase, E1 component
LGL91_05225	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL91_05230	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL91_05235	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGL91_05245	COG1271	oxidase subunit
LGL91_05250	COG1294	oxidase, subunit
LGL91_05255	COG4890	Cyd operon protein YbgT
LGL91_05260	COG3790	cyd operon protein YbgE
LGL91_05265	COG0824	Thioesterase
LGL91_05270	COG0811	peptide transport
LGL91_05275	COG0848	biopolymer transport protein
LGL91_05280	COG3064	Membrane
LGL91_05280	COG3064	Membrane
LGL91_05285	COG0823	Involved in the tonB-independent uptake of proteins
LGL91_05290	COG2885	chlorophyll binding
LGL91_05295	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LGL91_05335	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGL91_05345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_05345	COG2205	protein histidine kinase activity
LGL91_05355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL91_05360	COG0588	phosphoglycerate mutase activity
LGL91_05370	COG2017	converts alpha-aldose to the beta-anomer
LGL91_05380	COG1085	galactose-1-phosphate uridylyltransferase
LGL91_05385	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGL91_05400	COG2005	Transcriptional regulator
LGL91_05400	COG3585	molybdate ion transport
LGL91_05410	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGL91_05415	COG4149	molybdate abc transporter
LGL91_05425	COG0561	phosphatase activity
LGL91_05430	COG2706	6-phosphogluconolactonase activity
LGL91_05445	COG0156	8-amino-7-oxononanoate synthase activity
LGL91_05450	COG2226	methyltransferase
LGL91_05465	COG0556	nucleotide-excision repair
LGL91_05470	COG4628	conserved protein (DUF2132)
LGL91_05485	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL91_05490	COG1120	ATPase activity
LGL91_05495	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGL91_05500	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGL91_05510	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGL91_05515	COG0314	molybdopterin synthase activity
LGL91_05520	COG0670	Belongs to the BI1 family
LGL91_05525	COG0842	Transport permease protein
LGL91_05530	COG0842	Transport permease protein
LGL91_05535	COG1131	(ABC) transporter
LGL91_05540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL91_05545	COG1309	transcriptional regulator
LGL91_05550	COG0513	Belongs to the DEAD box helicase family
LGL91_05555	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL91_05565	COG1686	Belongs to the peptidase S11 family
LGL91_05570	COG0277	FAD linked oxidase domain protein
LGL91_05590	COG2261	transglycosylase associated protein
LGL91_05600	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LGL91_05610	COG3639	organic phosphonate transmembrane transporter activity
LGL91_05615	COG4807	Protein conserved in bacteria
LGL91_05620	COG2897	thiosulfate sulfurtransferase activity
LGL91_05625	COG1732	Glycine betaine
LGL91_05635	COG1174	glycine betaine transport
LGL91_05640	COG1125	glycine betaine transport
LGL91_05645	COG1174	glycine betaine transport
LGL91_05650	COG0531	amino acid
LGL91_05655	COG1982	Orn Lys Arg decarboxylase major
LGL91_05665	COG0697	spore germination
LGL91_05680	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGL91_05685	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LGL91_05690	COG1126	abc transporter atp-binding protein
LGL91_05695	COG0765	amino acid transport
LGL91_05700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_05720	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGL91_05725	COG2239	Acts as a magnesium transporter
LGL91_05730	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL91_05735	COG0488	(ABC) transporter
LGL91_05740	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL91_05745	COG0303	'Molybdopterin
LGL91_05765	COG0583	DNA-binding transcription factor activity
LGL91_05770	COG0477	Major facilitator Superfamily
LGL91_05775	COG0302	gtp cyclohydrolase
LGL91_05780	COG2311	Membrane
LGL91_05805	COG2949	membrane
LGL91_05810	COG0281	malic enzyme
LGL91_05820	COG0583	DNA-binding transcription factor activity
LGL91_05830	COG1346	cytolysis
LGL91_05835	COG1380	Effector of murein hydrolase LrgA
LGL91_05845	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL91_05845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL91_05850	COG0489	protein tyrosine kinase activity
LGL91_05855	COG0572	uridine kinase
LGL91_05860	COG0717	Belongs to the dCTP deaminase family
LGL91_05865	COG2982	Protein involved in outer membrane biogenesis
LGL91_05870	COG3069	C4-dicarboxylate transmembrane transporter activity
LGL91_05875	COG1253	flavin adenine dinucleotide binding
LGL91_05880	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL91_05885	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL91_05890	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGL91_05900	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGL91_05900	COG0140	phosphoribosyl-ATP diphosphatase activity
LGL91_05910	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGL91_05920	COG0131	Imidazoleglycerol-phosphate dehydratase
LGL91_05920	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL91_05925	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGL91_05930	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGL91_05945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL91_05950	COG0625	glutathione transferase activity
LGL91_05965	COG0626	cystathionine gamma-synthase activity
LGL91_05975	COG1686	Belongs to the peptidase S11 family
LGL91_05980	COG1760	l-serine dehydratase
LGL91_05985	COG0814	amino acid
LGL91_05990	COG1349	DNA-binding transcription factor activity
LGL91_06000	COG0671	phosphoesterase, PA-phosphatase related
LGL91_06010	COG2985	domain, Protein
LGL91_06010	COG0569	domain protein
LGL91_06030	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGL91_06035	COG3842	ATPase activity
LGL91_06040	COG1176	ABC-type spermidine putrescine transport system, permease component I
LGL91_06045	COG1177	transmembrane transport
LGL91_06060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_06065	COG4160	amino acid transport
LGL91_06070	COG4215	(ABC) transporter
LGL91_06075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_06080	COG1126	abc transporter atp-binding protein
LGL91_06090	COG0393	Putative heavy-metal-binding
LGL91_06095	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL91_06100	COG0702	epimerase
LGL91_06105	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LGL91_06110	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL91_06115	COG1151	hydroxylamine reductase activity
LGL91_06120	COG2431	L-lysine efflux transmembrane transporter activity
LGL91_06125	COG3593	DNA synthesis involved in DNA repair
LGL91_06130	COG2990	Protein conserved in bacteria
LGL91_06135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL91_06145	COG1278	Cold shock
LGL91_06150	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGL91_06155	COG0542	response to heat
LGL91_06160	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGL91_06170	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGL91_06180	COG0492	ferredoxin-NADP+ reductase activity
LGL91_06185	COG1522	sequence-specific DNA binding
LGL91_06190	COG3107	peptidoglycan biosynthetic process
LGL91_06190	COG1674	ftsk spoiiie
LGL91_06195	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGL91_06200	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGL91_06205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGL91_06210	COG2814	Major facilitator Superfamily
LGL91_06215	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGL91_06220	COG1882	Formate acetyltransferase
LGL91_06225	COG2116	formate transmembrane transporter activity
LGL91_06230	COG1944	ATP diphosphatase activity
LGL91_06235	COG0252	asparaginase activity
LGL91_06245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGL91_06255	COG0539	negative regulation of cytoplasmic translation
LGL91_06265	COG2333	competence protein COMEC
LGL91_06265	COG0658	competence protein
LGL91_06275	COG1663	tetraacyldisaccharide 4'-kinase activity
LGL91_06280	COG5383	Protein conserved in bacteria
LGL91_06290	COG1278	Cold shock
LGL91_06295	COG2835	tetraacyldisaccharide 4'-kinase activity
LGL91_06300	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LGL91_06305	COG3173	Aminoglycoside phosphotransferase
LGL91_06310	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LGL91_06315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL91_06320	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LGL91_06330	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LGL91_06335	COG2989	Protein conserved in bacteria
LGL91_06340	COG3108	Peptidase M15
LGL91_06345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGL91_06350	COG1448	Aminotransferase
LGL91_06365	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGL91_06370	COG0308	aminopeptidase N
LGL91_06375	COG0167	dihydroorotate dehydrogenase activity
LGL91_06385	COG0633	Ferredoxin
LGL91_06385	COG3217	Mosc domain protein beta barrel domain protein
LGL91_06390	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL91_06390	COG0116	Belongs to the methyltransferase superfamily
LGL91_06395	COG0488	(ABC) transporter
LGL91_06400	COG2995	paraquat-inducible protein a
LGL91_06405	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL91_06405	COG3008	intermembrane lipid transfer
LGL91_06410	COG3009	Protein conserved in bacteria
LGL91_06415	COG3130	regulation of translation
LGL91_06420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGL91_06425	COG1067	ATP-dependent peptidase activity
LGL91_06430	COG3120	sequence-specific DNA binding
LGL91_06440	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LGL91_06445	COG3070	regulator of competence-specific genes
LGL91_06450	COG1289	transmembrane transporter activity
LGL91_06455	COG3304	Inner membrane component domain
LGL91_06460	COG0210	DNA helicase
LGL91_06465	COG1803	Methylglyoxal synthase
LGL91_06475	COG1832	CoA-binding protein
LGL91_06480	COG3785	DNA binding
LGL91_06485	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL91_06490	COG1254	Belongs to the acylphosphatase family
LGL91_06495	COG2920	part of a sulfur-relay system
LGL91_06505	COG0288	reversible hydration of carbon dioxide
LGL91_06525	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LGL91_06530	COG2943	transferase activity, transferring hexosyl groups
LGL91_06535	COG0346	lactoylglutathione lyase activity
LGL91_06550	COG1560	Kdo2-lipid A biosynthetic process
LGL91_06560	COG0628	permease
LGL91_06585	COG0418	dihydroorotase activity
LGL91_06600	COG1530	ribonuclease E activity
LGL91_06605	COG0564	pseudouridine synthase activity
LGL91_06610	COG0424	maF-like protein
LGL91_06615	COG1399	metal-binding, possibly nucleic acid-binding protein
LGL91_06620	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGL91_06630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGL91_06635	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGL91_06645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL91_06650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL91_06655	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGL91_06660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGL91_06665	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGL91_06670	COG0470	DNA polymerase III
LGL91_06675	COG0084	hydrolase, TatD family'
LGL91_06680	COG1263	PTS System
LGL91_06680	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_06685	COG0537	adenosine 5'-monophosphoramidase activity
LGL91_06690	COG5633	Lipoprotein
LGL91_06695	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LGL91_06710	COG3150	esterase
LGL91_06715	COG1252	NADH dehydrogenase
LGL91_06720	COG3134	Outer membrane lipoprotein
LGL91_06725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGL91_06730	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL91_06740	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL91_06760	COG2850	peptidyl-arginine hydroxylation
LGL91_06765	COG2205	protein histidine kinase activity
LGL91_06770	COG0745	RESPONSE REGULATOR receiver
LGL91_06780	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGL91_06785	COG2915	High frequency lysogenization protein hflD homolog
LGL91_06790	COG0482	sulfurtransferase activity
LGL91_06800	COG1187	pseudouridine synthase activity
LGL91_06805	COG0538	isocitrate dehydrogenase activity
LGL91_06810	COG2771	luxR family
LGL91_06815	COG3916	Acyl-homoserine-lactone synthase
LGL91_06820	COG2723	6-phospho-beta-galactosidase activity
LGL91_06825	COG0339	signal peptide processing
LGL91_06835	COG3493	citrate carrier protein
LGL91_06840	COG4565	transcriptional regulatory protein
LGL91_06845	COG3290	protein histidine kinase activity
LGL91_06850	COG0471	metal ion transport
LGL91_06890	COG4977	sequence-specific DNA binding
LGL91_06895	COG1702	phosphate starvation-inducible protein PhoH
LGL91_06900	COG0387	Pfam Sodium calcium exchanger
LGL91_06905	COG2375	cellular response to nickel ion
LGL91_06910	COG3850	Histidine kinase
LGL91_06920	COG1294	oxidase, subunit
LGL91_06925	COG1271	oxidase subunit
LGL91_06930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL91_06935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGL91_06940	COG3138	arginine N-succinyltransferase
LGL91_06950	COG3724	N-succinylarginine dihydrolase activity
LGL91_06970	COG1228	amidohydrolase
LGL91_06980	COG0402	S-adenosylhomocysteine deaminase activity
LGL91_07000	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL91_07005	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LGL91_07010	COG3383	formate dehydrogenase (NAD+) activity
LGL91_07015	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL91_07020	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGL91_07030	COG3260	NADH ubiquinone oxidoreductase 20
LGL91_07035	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_07040	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LGL91_07040	COG3261	NADH dehydrogenase
LGL91_07045	COG0650	Formate hydrogenlyase subunit 4
LGL91_07050	COG0651	ATP synthesis coupled electron transport
LGL91_07055	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL91_07065	COG0375	protein maturation
LGL91_07070	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LGL91_07075	COG0298	carbon dioxide binding
LGL91_07080	COG0409	Hydrogenase expression formation protein
LGL91_07085	COG0309	Hydrogenase expression formation protein (HypE)
LGL91_07105	COG0012	GTP binding
LGL91_07115	COG0193	aminoacyl-tRNA hydrolase activity
LGL91_07125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGL91_07135	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGL91_07140	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGL91_07145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGL91_07150	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL91_07165	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LGL91_07170	COG0659	secondary active sulfate transmembrane transporter activity
LGL91_07175	COG3706	GGDEF domain
LGL91_07200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL91_07210	COG3381	protein complex oligomerization
LGL91_07230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL91_07240	COG0673	inositol 2-dehydrogenase activity
LGL91_07245	COG0728	peptidoglycan biosynthetic process
LGL91_07280	COG3102	Protein conserved in bacteria
LGL91_07285	COG3142	Participates in the control of copper homeostasis
LGL91_07300	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LGL91_07305	COG1801	Protein of unknown function DUF72
LGL91_07315	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGL91_07320	COG0494	nUDIX hydrolase
LGL91_07330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LGL91_07340	COG2255	four-way junction helicase activity
LGL91_07345	COG3104	oligopeptide transport
LGL91_07350	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL91_07355	COG1121	(ABC) transporter
LGL91_07360	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LGL91_07365	COG0739	heme binding
LGL91_07370	COG1560	Kdo2-lipid A biosynthetic process
LGL91_07375	COG0469	pyruvate kinase activity
LGL91_07380	COG1737	Transcriptional regulator
LGL91_07385	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGL91_07390	COG0800	Aldolase
LGL91_07400	COG2076	Multidrug Resistance protein
LGL91_07405	COG0251	oxidation-reduction process
LGL91_07410	COG1199	ATP-dependent helicase activity
LGL91_07415	COG1214	PFAM Peptidase M22, glycoprotease
LGL91_07425	COG0318	PFAM AMP-dependent synthetase and ligase
LGL91_07430	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LGL91_07435	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LGL91_07440	COG2894	cell division
LGL91_07445	COG0850	regulation of cytokinetic process
LGL91_07450	COG3100	YcgL domain-containing protein
LGL91_07455	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGL91_07460	COG2983	Belongs to the UPF0260 family
LGL91_07480	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL91_07490	COG2719	SpoVR family
LGL91_07495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGL91_07500	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGL91_07505	COG2814	Major facilitator Superfamily
LGL91_07515	COG2202	Pas domain
LGL91_07515	COG2200	EAL domain
LGL91_07515	COG2199	diguanylate cyclase activity
LGL91_07540	COG2718	Belongs to the UPF0229 family
LGL91_07545	COG2766	serine protein kinase
LGL91_07555	COG3713	MltA-interacting MipA family protein
LGL91_07560	COG2194	sulfuric ester hydrolase activity
LGL91_07575	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL91_07580	COG3139	Protein of unknown function (DUF1315)
LGL91_07585	COG1335	isochorismatase
LGL91_07590	COG0252	asparaginase activity
LGL91_07595	COG0616	signal peptide processing
LGL91_07600	COG0778	Nitroreductase
LGL91_07610	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL91_07620	COG0494	nUDIX hydrolase
LGL91_07625	COG0708	Exodeoxyribonuclease III
LGL91_07660	COG0788	formyltetrahydrofolate deformylase activity
LGL91_07670	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGL91_07675	COG0745	RESPONSE REGULATOR receiver
LGL91_07695	COG1454	alcohol dehydrogenase
LGL91_07695	COG1012	belongs to the aldehyde dehydrogenase family
LGL91_07705	COG2095	MarC family integral membrane protein
LGL91_07725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL91_07740	COG3099	Belongs to the UPF0263 family
LGL91_07745	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL91_07765	COG2350	Protein conserved in bacteria
LGL91_07785	COG3710	Transcriptional regulator
LGL91_07820	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LGL91_07845	COG0727	PFAM Uncharacterised protein family (UPF0153)
LGL91_07850	COG3047	cAMP biosynthetic process
LGL91_07865	COG0133	tryptophan synthase activity
LGL91_07870	COG0135	phosphoribosylanthranilate isomerase activity
LGL91_07870	COG0134	indole-3-glycerol-phosphate synthase activity
LGL91_07880	COG0512	Glutamine amidotransferase of anthranilate synthase
LGL91_07890	COG0613	PHP domain protein
LGL91_07895	COG0009	L-threonylcarbamoyladenylate synthase
LGL91_07900	COG1187	pseudouridine synthase activity
LGL91_07910	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_07915	COG0616	signal peptide processing
LGL91_07930	COG0583	DNA-binding transcription factor activity
LGL91_07950	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGL91_07960	COG0671	phosphoesterase, PA-phosphatase related
LGL91_07965	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LGL91_07970	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LGL91_07990	COG0023	Translation Initiation Factor
LGL91_08000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL91_08005	COG5002	protein histidine kinase activity
LGL91_08005	COG5001	Diguanylate cyclase
LGL91_08005	COG3447	MASE1 domain protein
LGL91_08010	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LGL91_08015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGL91_08025	COG4659	FMN binding
LGL91_08035	COG3708	Transcriptional regulator
LGL91_08035	COG2207	Transcriptional regulator
LGL91_08050	COG4657	Part of a membrane complex involved in electron transport
LGL91_08060	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGL91_08070	COG0673	inositol 2-dehydrogenase activity
LGL91_08075	COG0385	Bile acid
LGL91_08080	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGL91_08100	COG5339	Protein conserved in bacteria
LGL91_08105	COG1482	cell wall glycoprotein biosynthetic process
LGL91_08110	COG0114	fumarate hydratase activity
LGL91_08135	COG1940	carbohydrate kinase activity
LGL91_08140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGL91_08160	COG1742	UPF0060 membrane protein
LGL91_08165	COG4221	oxidoreductase activity
LGL91_08170	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL91_08250	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL91_08290	COG1011	Hydrolase
LGL91_08300	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGL91_08305	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGL91_08310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL91_08315	COG0589	response to stress
LGL91_08345	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGL91_08350	COG3623	hexulose-6-phosphate isomerase
LGL91_08355	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LGL91_08360	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LGL91_08370	COG0531	amino acid
LGL91_08380	COG0745	RESPONSE REGULATOR receiver
LGL91_08385	COG2205	protein histidine kinase activity
LGL91_08395	COG2207	Transcriptional regulator
LGL91_08400	COG1881	PFAM PEBP family protein
LGL91_08410	COG3591	Belongs to the peptidase S1B family
LGL91_08415	COG1643	Atp-dependent helicase
LGL91_08420	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGL91_08425	COG3784	Protein of unknown function (DUF1318)
LGL91_08440	COG2911	Protein conserved in bacteria
LGL91_08445	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGL91_08450	COG3187	Heat shock protein
LGL91_08455	COG3042	response to heat
LGL91_08460	COG1285	pathogenesis
LGL91_08470	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_08470	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGL91_08470	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGL91_08470	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGL91_08485	COG4166	transmembrane transport
LGL91_08490	COG2866	Carboxypeptidase
LGL91_08495	COG4948	Mandelate Racemase Muconate Lactonizing
LGL91_08500	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGL91_08510	COG5642	Protein of unknown function (DUF2384)
LGL91_08515	COG5654	RES domain protein
LGL91_08520	COG3768	UPF0283 membrane protein
LGL91_08525	COG3106	COG3106 Predicted ATPase
LGL91_08535	COG1983	PspC domain protein
LGL91_08545	COG1842	Phage shock protein A
LGL91_08550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LGL91_08565	COG4166	transmembrane transport
LGL91_08575	COG4171	peptide transport system, permease
LGL91_08580	COG4172	Belongs to the ABC transporter superfamily
LGL91_08585	COG4172	Belongs to the ABC transporter superfamily
LGL91_08595	COG3104	oligopeptide transport
LGL91_08605	COG0484	heat shock protein binding
LGL91_08650	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGL91_08655	COG3133	Outer membrane lipoprotein
LGL91_08660	COG1846	Transcriptional regulator
LGL91_08670	COG4989	oxidoreductase activity
LGL91_08675	COG3313	Fe-S protein
LGL91_08680	COG2194	sulfuric ester hydrolase activity
LGL91_08685	COG1309	transcriptional regulator
LGL91_08690	COG1902	pentaerythritol trinitrate reductase activity
LGL91_08705	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGL91_08710	COG0791	NLP P60 protein
LGL91_08715	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL91_08725	COG1609	Transcriptional regulator
LGL91_08730	COG0583	DNA-binding transcription factor activity
LGL91_08735	COG2814	Major facilitator Superfamily
LGL91_08740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL91_08745	COG0307	riboflavin synthase, alpha
LGL91_08780	COG1376	ErfK ybiS ycfS ynhG family protein
LGL91_08780	COG1388	LysM domain
LGL91_08785	COG2166	iron-sulfur cluster assembly
LGL91_08795	COG0719	Fe-S assembly protein
LGL91_08800	COG0396	ATPase activity
LGL91_08805	COG0719	Fe-S assembly protein
LGL91_08810	COG0316	Belongs to the HesB IscA family
LGL91_08815	COG2050	protein possibly involved in aromatic compounds catabolism
LGL91_08820	COG0247	lactate metabolic process
LGL91_08820	COG0277	FAD linked oxidase domain protein
LGL91_08825	COG0628	permease
LGL91_08835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL91_08835	COG0574	Belongs to the PEP-utilizing enzyme family
LGL91_08840	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGL91_08845	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL91_08855	COG4771	TonB-dependent receptor
LGL91_08860	COG3720	iron ion transport
LGL91_08865	COG4558	Periplasmic binding protein
LGL91_08870	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL91_08875	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LGL91_08885	COG0095	Lipoate-protein ligase
LGL91_08890	COG0791	NLP P60 protein
LGL91_08895	COG2076	Multidrug Resistance protein
LGL91_08900	COG2076	Multidrug Resistance protein
LGL91_08905	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGL91_08920	COG0463	Glycosyl transferase, family 2
LGL91_08925	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL91_08935	COG4139	cobalamin transport
LGL91_09005	COG0776	regulation of translation
LGL91_09080	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGL91_09085	COG1121	(ABC) transporter
LGL91_09090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL91_09095	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL91_09100	COG3001	Fructosamine kinase
LGL91_09110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL91_09130	COG1823	symporter activity
LGL91_09135	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL91_09145	COG2814	Major facilitator Superfamily
LGL91_09155	COG0501	Belongs to the peptidase M48B family
LGL91_09160	COG0793	Belongs to the peptidase S41A family
LGL91_09170	COG1956	GAF domain-containing protein
LGL91_09175	COG2995	paraquat-inducible protein a
LGL91_09180	COG3008	intermembrane lipid transfer
LGL91_09185	COG3706	GGDEF domain
LGL91_09185	COG4251	negative regulation of phosphorylation
LGL91_09185	COG5001	Diguanylate cyclase
LGL91_09185	COG2203	Gaf domain
LGL91_09320	COG4695	Portal protein
LGL91_09415	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL91_09475	COG4974	Belongs to the 'phage' integrase family
LGL91_09485	COG1276	copper resistance
LGL91_09490	COG2372	response to copper ion
LGL91_09495	COG1528	Iron-storage protein
LGL91_09510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL91_09515	COG1770	oligopeptidase
LGL91_09525	COG3097	Belongs to the UPF0267 family
LGL91_09530	COG3141	response to X-ray
LGL91_09535	COG0513	Belongs to the DEAD box helicase family
LGL91_09555	COG0494	nUDIX hydrolase
LGL91_09560	COG1760	l-serine dehydratase
LGL91_09565	COG1253	flavin adenine dinucleotide binding
LGL91_09570	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_09570	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_09575	COG3715	PTS system
LGL91_09580	COG3716	PTS system mannose fructose sorbose family IID component
LGL91_09585	COG4811	Protein of unknown function (DUF986)
LGL91_09590	COG1971	Probably functions as a manganese efflux pump
LGL91_09610	COG1960	acyl-CoA dehydrogenase activity
LGL91_09620	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGL91_09650	COG2226	methyltransferase
LGL91_09660	COG1496	oxidoreductase activity
LGL91_09685	COG1113	amino acid transport
LGL91_09730	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LGL91_09785	COG4386	tail sheath protein
LGL91_09810	COG4397	Mu-like prophage major head subunit gpT
LGL91_09840	COG4383	Mu-like prophage protein gp29
LGL91_09895	COG4382	Mu-like prophage protein Gp16
LGL91_09960	COG3423	Transcriptional regulator
LGL91_09995	COG2207	Transcriptional regulator
LGL91_10015	COG1132	(ABC) transporter
LGL91_10025	COG5001	Diguanylate cyclase
LGL91_10025	COG4251	negative regulation of phosphorylation
LGL91_10025	COG3706	GGDEF domain
LGL91_10025	COG2203	Gaf domain
LGL91_10045	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGL91_10065	COG1278	Cold shock
LGL91_10080	COG2169	Transcriptional regulator
LGL91_10080	COG1917	Cupin 2, conserved barrel domain protein
LGL91_10085	COG1447	Phosphotransferase system cellobiose-specific component IIA
LGL91_10090	COG2723	6-phospho-beta-galactosidase activity
LGL91_10095	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL91_10100	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL91_10105	COG1187	pseudouridine synthase activity
LGL91_10115	COG3122	Protein conserved in bacteria
LGL91_10120	COG1757	Na H antiporter
LGL91_10135	COG2235	arginine
LGL91_10160	COG0076	glutamate decarboxylase activity
LGL91_10165	COG0531	amino acid
LGL91_10200	COG2153	protein acetylation
LGL91_10205	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGL91_10240	COG0840	transmembrane signaling receptor activity
LGL91_10245	COG2801	Transposase and inactivated derivatives
LGL91_10270	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL91_10310	COG3646	Phage regulatory protein
LGL91_10330	COG3772	lysozyme
LGL91_10355	COG1403	HNH endonuclease
LGL91_10370	COG4626	Terminase
LGL91_10370	COG1802	Transcriptional regulator
LGL91_10415	COG5532	Uncharacterized conserved protein (DUF2303)
LGL91_10420	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL91_10470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGL91_10475	COG0322	excinuclease ABC activity
LGL91_10480	COG2197	response regulator
LGL91_10505	COG1113	amino acid transport
LGL91_10515	COG0531	amino acid
LGL91_10520	COG3710	Transcriptional regulator
LGL91_10525	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL91_10530	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL91_10530	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL91_10530	COG0506	proline dehydrogenase activity
LGL91_10535	COG1126	abc transporter atp-binding protein
LGL91_10540	COG0765	amino acid transport
LGL91_10545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_10550	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGL91_10560	COG1191	sigma factor activity
LGL91_10600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGL91_10605	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL91_10620	COG1677	Flagellar hook-basal body complex protein FliE
LGL91_10630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGL91_10640	COG1157	protein secretion by the type III secretion system
LGL91_10655	COG1580	Controls the rotational direction of flagella during chemotaxis
LGL91_10725	COG1749	Flagellar hook protein flgE
LGL91_10735	COG1558	bacterial-type flagellum-dependent cell motility
LGL91_10740	COG1815	bacterial-type flagellum-dependent cell motility
LGL91_10750	COG2747	anti-sigma28 factor FlgM
LGL91_10755	COG3418	PFAM FlgN family protein
LGL91_10765	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL91_10770	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL91_10775	COG1404	Belongs to the peptidase S8 family
LGL91_10775	COG4935	Belongs to the peptidase S8 family
LGL91_10780	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LGL91_10785	COG0745	RESPONSE REGULATOR receiver
LGL91_10795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGL91_10800	COG0840	transmembrane signaling receptor activity
LGL91_10805	COG0840	transmembrane signaling receptor activity
LGL91_10810	COG0835	chemotaxis
LGL91_10815	COG2198	Histidine kinase
LGL91_10815	COG0643	Histidine kinase
LGL91_10820	COG1360	Flagellar Motor Protein
LGL91_10840	COG0589	response to stress
LGL91_10850	COG1285	pathogenesis
LGL91_10855	COG0840	transmembrane signaling receptor activity
LGL91_10875	COG1609	Transcriptional regulator
LGL91_10885	COG0604	alcohol dehydrogenase
LGL91_10885	COG3321	synthase
LGL91_10885	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_10935	COG0471	metal ion transport
LGL91_10950	COG3051	citrate lyase alpha subunit
LGL91_10955	COG2301	Belongs to the HpcH HpaI aldolase family
LGL91_10960	COG3052	prosthetic group binding
LGL91_10965	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LGL91_10970	COG3290	protein histidine kinase activity
LGL91_10975	COG4565	transcriptional regulatory protein
LGL91_10990	COG2271	Major facilitator Superfamily
LGL91_10995	COG1840	ABC-type Fe3 transport system, periplasmic component
LGL91_11005	COG3842	ATPase activity
LGL91_11020	COG0582	viral genome integration into host DNA
LGL91_11045	COG1475	DNA binding
LGL91_11170	COG1289	transmembrane transporter activity
LGL91_11180	COG2925	Exonuclease
LGL91_11185	COG0531	amino acid
LGL91_11190	COG4771	TonB-dependent receptor
LGL91_11200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL91_11210	COG0833	amino acid
LGL91_11215	COG0583	DNA-binding transcription factor activity
LGL91_11225	COG2855	membrane
LGL91_11230	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGL91_11235	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL91_11235	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGL91_11235	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL91_11240	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL91_11255	COG3005	denitrification pathway
LGL91_11260	COG0243	molybdopterin cofactor binding
LGL91_11280	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGL91_11290	COG0246	Mannitol dehydrogenase
LGL91_11300	COG0523	cobalamin synthesis protein
LGL91_11305	COG0671	phosphoesterase, PA-phosphatase related
LGL91_11310	COG0791	NLP P60 protein
LGL91_11315	COG2200	EAL domain
LGL91_11320	COG4166	transmembrane transport
LGL91_11325	COG4174	ABC transporter (Permease)
LGL91_11330	COG4239	(ABC) transporter, permease
LGL91_11335	COG4172	Belongs to the ABC transporter superfamily
LGL91_11345	COG2814	Major facilitator Superfamily
LGL91_11350	COG1187	pseudouridine synthase activity
LGL91_11355	COG1061	Type III restriction enzyme res subunit
LGL91_11370	COG3082	Protein of unknown function (DUF1414)
LGL91_11375	COG3083	sulfuric ester hydrolase activity
LGL91_11405	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGL91_11430	COG2223	nitrite transmembrane transporter activity
LGL91_11435	COG0642	Histidine kinase
LGL91_11435	COG2198	Histidine kinase
LGL91_11445	COG2205	protein histidine kinase activity
LGL91_11445	COG0784	Response regulator, receiver
LGL91_11455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL91_11460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL91_11470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL91_11480	COG4574	serine-type endopeptidase inhibitor activity
LGL91_11490	COG2246	polysaccharide biosynthetic process
LGL91_11505	COG0814	amino acid
LGL91_11530	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGL91_11535	COG0596	Alpha beta hydrolase
LGL91_11540	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGL91_11545	COG1169	isochorismate synthase
LGL91_11550	COG4575	ribosome binding
LGL91_11565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_11570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGL91_11580	COG0839	Belongs to the complex I subunit 6 family
LGL91_11585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_11590	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGL91_11595	COG1034	ATP synthesis coupled electron transport
LGL91_11615	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_11620	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL91_11625	COG0583	DNA-binding transcription factor activity
LGL91_11630	COG0436	Aminotransferase
LGL91_11635	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL91_11640	COG0471	metal ion transport
LGL91_11640	COG0490	domain, Protein
LGL91_11650	COG3013	Belongs to the UPF0304 family
LGL91_11655	COG3092	negative regulation of chromosome organization
LGL91_11665	COG0857	belongs to the CobB CobQ family
LGL91_11665	COG0280	phosphate acetyltransferase
LGL91_11670	COG1609	Transcriptional regulator
LGL91_11685	COG3037	sugar-specific permease SgaT UlaA
LGL91_11690	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LGL91_11695	COG0622	Phosphoesterase
LGL91_11705	COG0625	glutathione transferase activity
LGL91_11710	COG1090	epimerase
LGL91_11720	COG4160	amino acid transport
LGL91_11725	COG4215	(ABC) transporter
LGL91_11740	COG0163	prenyltransferase activity
LGL91_11745	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGL91_11750	COG1286	toxin biosynthetic process
LGL91_11755	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LGL91_11760	COG0285	dihydrofolate synthase activity
LGL91_11770	COG0586	Pfam SNARE associated Golgi protein
LGL91_11780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL91_11805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL91_11810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL91_11840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL91_11855	COG3101	peptidyl-lysine hydroxylation
LGL91_11860	COG0730	response to heat
LGL91_11865	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LGL91_11875	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL91_11880	COG2840	Smr protein MutS2
LGL91_11885	COG2062	phosphohistidine phosphatase, SixA
LGL91_11895	COG0183	Belongs to the thiolase family
LGL91_11900	COG3691	Protein conserved in bacteria
LGL91_11915	COG4235	cytochrome complex assembly
LGL91_11915	COG3088	subunit of a heme lyase
LGL91_11920	COG4235	cytochrome complex assembly
LGL91_11920	COG3088	subunit of a heme lyase
LGL91_11925	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL91_11930	COG1138	Cytochrome C-type biogenesis protein
LGL91_11935	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LGL91_11940	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL91_11945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL91_11950	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL91_11965	COG0582	viral genome integration into host DNA
LGL91_12030	COG2824	Alkylphosphonate utilization operon protein PhnA
LGL91_12035	COG2951	lytic endotransglycosylase activity
LGL91_12040	COG1598	PFAM Uncharacterised protein family UPF0150
LGL91_12050	COG3038	cytochrome b561
LGL91_12055	COG0436	Aminotransferase
LGL91_12065	COG3275	phosphorelay sensor kinase activity
LGL91_12070	COG3279	Response regulator of the LytR AlgR family
LGL91_12075	COG2223	nitrite transmembrane transporter activity
LGL91_12080	COG0837	glucose binding
LGL91_12100	COG1914	H( )-stimulated, divalent metal cation uptake system
LGL91_12105	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL91_12175	COG3530	Putative quorum-sensing-regulated virulence factor
LGL91_12180	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL91_12190	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LGL91_12200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_12215	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL91_12225	COG4208	sulfate ABC transporter
LGL91_12230	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGL91_12235	COG4150	thiosulfate binding
LGL91_12245	COG1737	Transcriptional regulator
LGL91_12250	COG2731	YhcH YjgK YiaL family protein
LGL91_12265	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL91_12270	COG2837	iron assimilation
LGL91_12280	COG3111	PFAM Bacterial OB fold (BOF) protein
LGL91_12295	COG1671	Belongs to the UPF0178 family
LGL91_12300	COG0281	malic enzyme
LGL91_12300	COG0280	phosphate acetyltransferase
LGL91_12305	COG0494	nUDIX hydrolase
LGL91_12310	COG3005	denitrification pathway
LGL91_12315	COG3043	anaerobic respiration
LGL91_12320	COG0243	molybdopterin cofactor binding
LGL91_12325	COG3062	negative regulation of establishment of protein localization
LGL91_12330	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL91_12330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL91_12335	COG2197	response regulator
LGL91_12345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL91_12355	COG1605	Chorismate mutase
LGL91_12360	COG1393	Belongs to the ArsC family
LGL91_12365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGL91_12370	COG1876	peptidase activity
LGL91_12380	COG0400	carboxylic ester hydrolase activity
LGL91_12400	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LGL91_12405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL91_12410	COG2716	regulation of RNA biosynthetic process
LGL91_12415	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGL91_12420	COG0628	permease
LGL91_12425	COG4783	chaperone-mediated protein folding
LGL91_12430	COG1393	Belongs to the ArsC family
LGL91_12435	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGL91_12440	COG2233	PERMEase
LGL91_12445	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGL91_12450	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGL91_12455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGL91_12460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL91_12470	COG0581	inorganic phosphate transmembrane transporter activity
LGL91_12475	COG0573	inorganic phosphate transmembrane transporter activity
LGL91_12480	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGL91_12495	COG2239	Acts as a magnesium transporter
LGL91_12500	COG0443	Heat shock 70 kDa protein
LGL91_12510	COG3121	Chaperone
LGL91_12530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL91_12540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL91_12545	COG0477	Major facilitator Superfamily
LGL91_12550	COG2205	protein histidine kinase activity
LGL91_12555	COG0745	RESPONSE REGULATOR receiver
LGL91_12560	COG3422	double-strand break repair
LGL91_12565	COG0826	peptidase U32
LGL91_12570	COG1597	lipid kinase activity
LGL91_12585	COG0351	phosphomethylpyrimidine kinase
LGL91_12595	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGL91_12595	COG0519	Catalyzes the synthesis of GMP from XMP
LGL91_12600	COG0517	IMP dehydrogenase activity
LGL91_12600	COG0516	GMP reductase activity
LGL91_12605	COG1570	exodeoxyribonuclease VII activity
LGL91_12610	COG1645	bacterial-type flagellum-dependent swarming motility
LGL91_12620	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL91_12625	COG2976	Protein conserved in bacteria
LGL91_12630	COG0124	histidyl-tRNA synthetase
LGL91_12650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGL91_12665	COG4953	penicillin-binding protein 1C
LGL91_12670	COG2373	Large extracellular alpha-helical protein
LGL91_12685	COG2975	iron-sulfur cluster assembly
LGL91_12690	COG0633	Ferredoxin
LGL91_12695	COG0443	Heat shock 70 kDa protein
LGL91_12710	COG0822	iron-sulfur transferase activity
LGL91_12720	COG1959	2 iron, 2 sulfur cluster binding
LGL91_12725	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LGL91_12735	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL91_12740	COG3683	transport system, periplasmic component
LGL91_12745	COG3711	transcriptional antiterminator
LGL91_12750	COG2814	Major facilitator Superfamily
LGL91_12760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL91_12760	COG1017	nitric oxide dioxygenase activity
LGL91_12765	COG2188	Transcriptional regulator
LGL91_12775	COG3457	Alanine racemase
LGL91_12780	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LGL91_12795	COG0347	Belongs to the P(II) protein family
LGL91_12800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL91_12800	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL91_12805	COG2204	response regulator
LGL91_12810	COG3170	Tfp pilus assembly protein FimV
LGL91_12815	COG2205	protein histidine kinase activity
LGL91_12830	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LGL91_12840	COG0560	Phosphoserine phosphatase
LGL91_12845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_12845	COG1263	PTS System
LGL91_12855	COG1737	Transcriptional regulator
LGL91_12875	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL91_12955	COG0305	Participates in initiation and elongation during chromosome replication
LGL91_12960	COG1484	DNA-dependent DNA replication
LGL91_13110	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL91_13120	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGL91_13130	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGL91_13145	COG0481	GTPase activity
LGL91_13150	COG3086	response to oxidative stress
LGL91_13160	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LGL91_13170	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGL91_13180	COG0513	Belongs to the DEAD box helicase family
LGL91_13195	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LGL91_13205	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGL91_13210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGL91_13215	COG0497	DNA recombination
LGL91_13220	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL91_13230	COG2867	negative regulation of translational initiation
LGL91_13235	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGL91_13270	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL91_13335	COG0582	viral genome integration into host DNA
LGL91_13340	COG0582	viral genome integration into host DNA
LGL91_13375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL91_13455	COG1069	ribulokinase activity
LGL91_13465	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL91_13470	COG1129	ABC transporter
LGL91_13495	COG1620	l-lactate permease
LGL91_13500	COG1304	FMN binding
LGL91_13505	COG0579	oxidoreductase
LGL91_13510	COG1278	Cold shock
LGL91_13540	COG1780	Probably involved in ribonucleotide reductase function
LGL91_13545	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL91_13555	COG4175	Glycine betaine
LGL91_13560	COG4176	ABC-type proline glycine betaine transport system permease component
LGL91_13565	COG2113	Glycine betaine
LGL91_13575	COG2814	Major facilitator Superfamily
LGL91_13580	COG1846	Transcriptional regulator
LGL91_13590	COG1566	PFAM secretion protein HlyD family protein
LGL91_13595	COG2814	Major facilitator Superfamily
LGL91_13600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL91_13605	COG3118	belongs to the thioredoxin family
LGL91_13615	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL91_13615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL91_13615	COG1042	CoA-binding domain protein
LGL91_13620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL91_13625	COG5544	Lipoprotein
LGL91_13650	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL91_13660	COG2011	ABC-type metal ion transport system permease component
LGL91_13665	COG1464	Belongs to the NlpA lipoprotein family
LGL91_13675	COG1720	tRNA m6t6A37 methyltransferase activity
LGL91_13680	COG0442	prolyl-tRNA aminoacylation
LGL91_13685	COG3015	lipoprotein NlpE involved in copper resistance
LGL91_13695	COG4681	YaeQ
LGL91_13705	COG4568	rho-dependent transcription termination
LGL91_13720	COG0346	lactoylglutathione lyase activity
LGL91_13735	COG0825	malonyl-CoA metabolic process
LGL91_13740	COG0587	DNA-directed DNA polymerase activity
LGL91_13745	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGL91_13765	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL91_13770	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LGL91_13780	COG0750	zinc metalloprotease
LGL91_13785	COG0575	Belongs to the CDS family
LGL91_13805	COG0528	UMP kinase activity
LGL91_13810	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGL91_13825	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LGL91_13830	COG2171	N-acyltransferase activity
LGL91_13845	COG0564	pseudouridine synthase activity
LGL91_13850	COG3098	single-species biofilm formation
LGL91_13865	COG1611	Belongs to the LOG family
LGL91_13875	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LGL91_13880	COG2363	Small membrane protein
LGL91_13885	COG0583	DNA-binding transcription factor activity
LGL91_13895	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGL91_13900	COG2166	iron-sulfur cluster assembly
LGL91_13905	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGL91_13910	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LGL91_13930	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL91_13935	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LGL91_13935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL91_13940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL91_13945	COG1074	ATP-dependent DNA helicase activity
LGL91_13950	COG1025	Belongs to the peptidase M16 family
LGL91_13955	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGL91_13960	COG4967	type IV pilus modification protein PilV
LGL91_13985	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGL91_13990	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LGL91_14000	COG3066	DNA modification
LGL91_14005	COG0861	Integral membrane protein TerC family
LGL91_14010	COG0667	Aldo Keto reductase
LGL91_14015	COG0477	Major facilitator Superfamily
LGL91_14020	COG0318	PFAM AMP-dependent synthetase and ligase
LGL91_14020	COG0204	Acyl-transferase
LGL91_14025	COG1609	Transcriptional regulator
LGL91_14035	COG0583	DNA-binding transcription factor activity
LGL91_14040	COG0583	DNA-binding transcription factor activity
LGL91_14095	COG2165	general secretion pathway protein
LGL91_14140	COG1127	ABC transporter
LGL91_14145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL91_14155	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGL91_14165	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGL91_14170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL91_14175	COG4974	Belongs to the 'phage' integrase family
LGL91_14180	COG0716	FMN binding
LGL91_14190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGL91_14200	COG1272	protein, Hemolysin III
LGL91_14220	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGL91_14225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL91_14230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL91_14235	COG0006	proline dipeptidase activity
LGL91_14245	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGL91_14255	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGL91_14260	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL91_14265	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGL91_14280	COG1279	arginine transmembrane transporter activity
LGL91_14290	COG0191	fructose-bisphosphate aldolase activity
LGL91_14295	COG0126	phosphoglycerate kinase activity
LGL91_14300	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGL91_14305	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGL91_14315	COG1166	arginine decarboxylase activity
LGL91_14320	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGL91_14335	COG0640	Transcriptional regulator
LGL91_14340	COG3091	SprT-like family
LGL91_14345	COG2356	endonuclease I
LGL91_14350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGL91_14355	COG0189	ligase activity
LGL91_14360	COG1678	Uncharacterized ACR, COG1678
LGL91_14365	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGL91_14370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL91_14380	COG2805	Type II/IV secretion system protein
LGL91_14385	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGL91_14390	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGL91_14395	COG0762	integral membrane protein
LGL91_14400	COG1872	DUF167
LGL91_14405	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGL91_14410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL91_14425	COG3171	Protein conserved in bacteria
LGL91_14435	COG1194	a g-specific adenine glycosylase
LGL91_14440	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LGL91_14445	COG0741	lytic transglycosylase activity
LGL91_14530	COG0583	DNA-binding transcription factor activity
LGL91_14545	COG3730	PTS system glucitol sorbitol-specific
LGL91_14550	COG3732	PTS system glucitol sorbitol-specific
LGL91_14555	COG3731	PTS system glucitol sorbitol-specific IIA component
LGL91_14560	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_14565	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_14570	COG1349	DNA-binding transcription factor activity
LGL91_14580	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL91_14585	COG1882	Formate acetyltransferase
LGL91_14590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGL91_14595	COG0814	amino acid
LGL91_14610	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_14615	COG1535	isochorismatase
LGL91_14615	COG3433	isochorismatase activity
LGL91_14620	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGL91_14625	COG1169	isochorismate synthase
LGL91_14630	COG4592	Periplasmic binding protein
LGL91_14640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL91_14645	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL91_14650	COG1120	ATPase activity
LGL91_14660	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGL91_14665	COG3251	PFAM MbtH domain protein
LGL91_14675	COG4774	siderophore transport
LGL91_14680	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGL91_14710	COG4964	Belongs to the GSP D family
LGL91_14770	COG0848	biopolymer transport protein
LGL91_14775	COG0811	peptide transport
LGL91_14780	COG0626	cystathionine gamma-synthase activity
LGL91_14785	COG0586	Pfam SNARE associated Golgi protein
LGL91_14790	COG2207	Transcriptional regulator
LGL91_14795	COG1979	alcohol dehydrogenase
LGL91_14800	COG0656	L-ascorbic acid biosynthetic process
LGL91_14810	COG2132	Multicopper oxidase
LGL91_14820	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGL91_14825	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL91_14830	COG0583	DNA-binding transcription factor activity
LGL91_14835	COG0187	DNA topoisomerase II activity
LGL91_14840	COG3150	esterase
LGL91_14845	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGL91_14850	COG3151	Protein conserved in bacteria
LGL91_14855	COG0494	nUDIX hydrolase
LGL91_14860	COG1538	Outer membrane efflux protein
LGL91_14865	COG5463	Belongs to the UPF0441 family
LGL91_14870	COG0754	glutathionylspermidine amidase activity
LGL91_14875	COG3384	dioxygenase
LGL91_14880	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGL91_14890	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LGL91_14890	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGL91_14900	COG3025	triphosphatase activity
LGL91_14905	COG4991	sh3 domain protein
LGL91_14910	COG0617	tRNA 3'-terminal CCA addition
LGL91_14915	COG1968	undecaprenyl-diphosphatase activity
LGL91_14920	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGL91_14925	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGL91_14930	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGL91_14935	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGL91_14940	COG0358	DNA primase activity
LGL91_14965	COG1201	RNA secondary structure unwinding
LGL91_15000	COG4983	Phage plasmid primase, P4 family domain protein
LGL91_15045	COG1028	Short-chain dehydrogenase reductase Sdr
LGL91_15070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL91_15100	COG3210	domain, Protein
LGL91_15105	COG2831	hemolysin activation secretion protein
LGL91_15110	COG1902	pentaerythritol trinitrate reductase activity
LGL91_15110	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGL91_15135	COG1451	nucleotide metabolic process
LGL91_15140	COG0673	inositol 2-dehydrogenase activity
LGL91_15145	COG0861	Integral membrane protein TerC family
LGL91_15150	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LGL91_15160	COG2721	sulfolactate sulfo-lyase activity
LGL91_15175	COG2271	Major facilitator Superfamily
LGL91_15190	COG0586	Pfam SNARE associated Golgi protein
LGL91_15205	COG4575	ribosome binding
LGL91_15210	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LGL91_15220	COG2259	Doxx family
LGL91_15225	COG0583	DNA-binding transcription factor activity
LGL91_15230	COG1741	Belongs to the pirin family
LGL91_15245	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGL91_15260	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL91_15265	COG2823	Periplasmic or secreted lipoprotein
LGL91_15270	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL91_15275	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LGL91_15280	COG2198	Histidine kinase
LGL91_15280	COG0784	Response regulator, receiver
LGL91_15280	COG5002	protein histidine kinase activity
LGL91_15290	COG1242	4 iron, 4 sulfur cluster binding
LGL91_15295	COG0070	glutamate synthase
LGL91_15295	COG0067	glutamate synthase
LGL91_15295	COG0069	glutamate synthase activity
LGL91_15300	COG0493	'glutamate synthase
LGL91_15310	COG2969	positive regulation of protein catabolic process
LGL91_15315	COG0625	glutathione transferase activity
LGL91_15320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGL91_15325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGL91_15330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGL91_15335	COG3105	Protein conserved in bacteria
LGL91_15340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL91_15350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGL91_15355	COG5007	Belongs to the BolA IbaG family
LGL91_15360	COG3113	response to antibiotic
LGL91_15365	COG2854	intermembrane phospholipid transfer
LGL91_15370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL91_15375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL91_15380	COG1127	ABC transporter
LGL91_15385	COG0530	calcium, potassium:sodium antiporter activity
LGL91_15390	COG0517	IMP dehydrogenase activity
LGL91_15390	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGL91_15395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGL91_15400	COG3117	lipopolysaccharide transmembrane transporter activity
LGL91_15405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGL91_15410	COG1137	ATPase activity
LGL91_15415	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGL91_15435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL91_15440	COG0540	Belongs to the ATCase OTCase family
LGL91_15445	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LGL91_15455	COG0366	Alpha amylase catalytic
LGL91_15460	COG1263	PTS System
LGL91_15460	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL91_15470	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGL91_15480	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL91_15485	COG3783	Cytochrome b(562)
LGL91_15490	COG0312	modulator of DNA gyrase
LGL91_15495	COG3028	Belongs to the UPF0307 family
LGL91_15500	COG2732	(Barnase) inhibitor
LGL91_15505	COG4290	ribonuclease
LGL91_15515	COG1289	transmembrane transporter activity
LGL91_15520	COG1566	PFAM secretion protein HlyD family protein
LGL91_15530	COG0583	DNA-binding transcription factor activity
LGL91_15535	COG0312	modulator of DNA gyrase
LGL91_15540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL91_15545	COG3164	Protein of unknown function
LGL91_15555	COG0424	maF-like protein
LGL91_15560	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGL91_15565	COG1792	Involved in formation and maintenance of cell shape
LGL91_15570	COG1077	Cell shape determining protein MreB Mrl
LGL91_15575	COG2199	diguanylate cyclase activity
LGL91_15575	COG2200	EAL domain
LGL91_15580	COG0604	alcohol dehydrogenase
LGL91_15585	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL91_15590	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LGL91_15600	COG0511	ligase activity, forming carbon-carbon bonds
LGL91_15605	COG0439	Biotin carboxylase
LGL91_15610	COG3924	membrane
LGL91_15615	COG4145	pantothenate transmembrane transporter activity
LGL91_15620	COG2264	protein methyltransferase activity
LGL91_15625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL91_15630	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGL91_15640	COG1560	Kdo2-lipid A biosynthetic process
LGL91_15650	COG1346	cytolysis
LGL91_15655	COG1380	Effector of murein hydrolase LrgA
LGL91_15660	COG0583	DNA-binding transcription factor activity
LGL91_15665	COG0025	NhaP-type Na H and K H
LGL91_15670	COG2252	PERMEase
LGL91_15685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGL91_15690	COG2315	Protein conserved in bacteria
LGL91_15695	COG1448	Aminotransferase
LGL91_15710	COG0604	alcohol dehydrogenase
LGL91_15720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL91_15725	COG0735	belongs to the Fur family
LGL91_15730	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGL91_15735	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGL91_15740	COG2937	Belongs to the GPAT DAPAT family
LGL91_15760	COG4580	involved in the transport of maltose and maltodextrins
LGL91_15775	COG2182	Extracellular solute-binding protein
LGL91_15780	COG1175	transmembrane transport
LGL91_15785	COG3833	ABC-type maltose transport systems, permease component
LGL91_15790	COG3223	Belongs to the PsiE family
LGL91_15800	COG0527	aspartate kinase activity
LGL91_15840	COG1222	aaa ATPase
LGL91_15925	COG0583	DNA-binding transcription factor activity
LGL91_15960	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGL91_16000	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LGL91_16005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGL91_16010	COG1739	Uncharacterized protein family UPF0029
LGL91_16020	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL91_16020	COG1024	Enoyl-CoA hydratase
LGL91_16030	COG0543	2 iron, 2 sulfur cluster binding
LGL91_16045	COG0250	Participates in transcription elongation, termination and antitermination
LGL91_16060	COG0805	protein transport
LGL91_16065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL91_16070	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL91_16075	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGL91_16080	COG3165	ubiquinone biosynthetic process from chorismate
LGL91_16085	COG2226	methyltransferase
LGL91_16090	COG1322	Protein conserved in bacteria
LGL91_16095	COG0586	Pfam SNARE associated Golgi protein
LGL91_16100	COG1966	Carbon starvation protein
LGL91_16115	COG0412	Dienelactone hydrolase
LGL91_16120	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGL91_16125	COG0583	DNA-binding transcription factor activity
LGL91_16130	COG0697	spore germination
LGL91_16140	COG0584	glycerophosphoryl diester phosphodiesterase
LGL91_16150	COG0395	ABC-type sugar transport system, permease component
LGL91_16155	COG1175	transmembrane transport
LGL91_16160	COG1653	transport
LGL91_16195	COG0410	ABC transporter
LGL91_16205	COG4177	L-phenylalanine transmembrane transporter activity
LGL91_16225	COG1929	Belongs to the glycerate kinase type-1 family
LGL91_16230	COG2610	gluconate transmembrane transporter activity
LGL91_16235	COG3835	regulator
LGL91_16245	COG2177	Part of the ABC transporter FtsEX involved in
LGL91_16250	COG2884	Cell division ATP-binding protein ftsE
LGL91_16255	COG0552	protein localization to endoplasmic reticulum
LGL91_16255	COG0552	protein localization to endoplasmic reticulum
LGL91_16260	COG0742	ribosomal rna small subunit methyltransferase
LGL91_16265	COG3776	membrane
LGL91_16280	COG3714	YhhN family
LGL91_16295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGL91_16305	COG0247	lactate metabolic process
LGL91_16315	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL91_16325	COG2271	Major facilitator Superfamily
LGL91_16330	COG0584	glycerophosphoryl diester phosphodiesterase
LGL91_16335	COG0561	phosphatase activity
LGL91_16340	COG2267	carboxylic ester hydrolase activity
LGL91_16345	COG1280	lysine exporter protein (LysE YggA)
LGL91_16350	COG0514	ATP-dependent DNA helicase (RecQ)
LGL91_16355	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LGL91_16360	COG2050	protein possibly involved in aromatic compounds catabolism
LGL91_16380	COG5564	TIM-barrel signal transduction protein
LGL91_16385	COG5441	Belongs to the UPF0261 family
LGL91_16395	COG0210	DNA helicase
LGL91_16405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL91_16410	COG3159	Protein conserved in bacteria
LGL91_16415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGL91_16420	COG5567	small periplasmic lipoprotein
LGL91_16430	COG3072	Adenylate cyclase
LGL91_16435	COG0181	hydroxymethylbilane synthase activity
LGL91_16440	COG1587	Uroporphyrinogen-III synthase
LGL91_16445	COG2959	enzyme of heme biosynthesis
LGL91_16450	COG3071	HemY protein
LGL91_16500	COG2244	polysaccharide biosynthetic process
LGL91_16505	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL91_16510	COG0456	acetyltransferase
LGL91_16515	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGL91_16520	COG1088	dTDP-glucose 4,6-dehydratase activity
LGL91_16525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGL91_16530	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL91_16535	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL91_16540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGL91_16545	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGL91_16550	COG3118	belongs to the thioredoxin family
LGL91_16560	COG0248	Ppx GppA phosphatase
LGL91_16570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL91_16585	COG3397	chitin binding
LGL91_16595	COG0129	dihydroxy-acid dehydratase activity
LGL91_16605	COG3978	acetolactate synthase activity
LGL91_16625	COG3085	chromosome segregation
LGL91_16630	COG0583	DNA-binding transcription factor activity
LGL91_16710	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL91_16720	COG0678	peroxiredoxin activity
LGL91_16720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL91_16725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL91_16765	COG0165	Argininosuccinate lyase
LGL91_16770	COG0137	argininosuccinate synthase activity
LGL91_16775	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL91_16825	COG0527	aspartate kinase activity
LGL91_16825	COG0460	homoserine dehydrogenase
LGL91_16830	COG0626	cystathionine gamma-synthase activity
LGL91_16835	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LGL91_16845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGL91_16850	COG1609	Transcriptional regulator
LGL91_16855	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL91_16860	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGL91_16865	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGL91_16870	COG1575	Belongs to the MenA family. Type 1 subfamily
LGL91_16875	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGL91_16880	COG3074	FtsZ-dependent cytokinesis
LGL91_16885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGL91_16890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGL91_16895	COG1494	fructose-1,6-bisphosphatase
LGL91_16900	COG2814	Major facilitator Superfamily
LGL91_16910	COG3152	Membrane
LGL91_16925	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGL91_16935	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL91_16940	COG3678	ATP-independent chaperone mediated protein folding
LGL91_16945	COG0745	RESPONSE REGULATOR receiver
LGL91_16950	COG2205	protein histidine kinase activity
LGL91_16955	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGL91_16960	COG1045	serine acetyltransferase
LGL91_16965	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGL91_16970	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LGL91_16975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL91_16980	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGL91_16985	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGL91_16990	COG4942	peptidase
LGL91_16995	COG2861	carbohydrate metabolic process
LGL91_17010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL91_17015	COG0859	PFAM glycosyl transferase family 9
LGL91_17020	COG0859	PFAM glycosyl transferase family 9
LGL91_17025	COG1519	Transferase
LGL91_17045	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGL91_17050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGL91_17055	COG2003	Belongs to the UPF0758 family
LGL91_17060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGL91_17065	COG0756	dUTP diphosphatase activity
LGL91_17070	COG1309	transcriptional regulator
LGL91_17075	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGL91_17080	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGL91_17085	COG1561	YicC-like family, N-terminal region
LGL91_17135	COG5001	Diguanylate cyclase
LGL91_17140	COG1024	Enoyl-CoA hydratase
LGL91_17145	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL91_17155	COG2860	membrane
LGL91_17160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL91_17170	COG1758	RNA polymerase activity
LGL91_17175	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL91_17180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL91_17185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGL91_17190	COG0786	glutamate:sodium symporter activity
LGL91_17195	COG2233	PERMEase
LGL91_17200	COG2982	Protein involved in outer membrane biogenesis
LGL91_17205	COG0456	acetyltransferase
LGL91_17220	COG1011	Hydrolase
LGL91_17235	COG3852	Histidine kinase
LGL91_17245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL91_17255	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGL91_17260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL91_17260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL91_17265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL91_17270	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGL91_17275	COG3084	Protein conserved in bacteria
LGL91_17285	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGL91_17310	COG2186	Transcriptional regulator
LGL91_17315	COG1609	Transcriptional regulator
LGL91_17320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL91_17330	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL91_17335	COG1129	ABC transporter
LGL91_17340	COG1869	D-ribose catabolic process
LGL91_17345	COG3158	transport of potassium into the cell
LGL91_17350	COG0714	Associated with various cellular activities
LGL91_17355	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LGL91_17365	COG2502	aspartate--ammonia ligase
LGL91_17370	COG1522	sequence-specific DNA binding
LGL91_17375	COG0716	FMN binding
LGL91_17380	COG0445	tRNA wobble uridine modification
LGL91_17385	COG0357	Ribosomal RNA small subunit methyltransferase G
LGL91_17390	COG3312	ion transport
LGL91_17395	COG0356	it plays a direct role in the translocation of protons across the membrane
LGL91_17405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGL91_17415	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGL91_17420	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGL91_17430	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGL91_17445	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGL91_17450	COG0573	inorganic phosphate transmembrane transporter activity
LGL91_17455	COG0581	inorganic phosphate transmembrane transporter activity
LGL91_17465	COG0704	Plays a role in the regulation of phosphate uptake
LGL91_17470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL91_17475	COG0765	amino acid transport
LGL91_17480	COG0765	amino acid transport
LGL91_17485	COG2252	PERMEase
LGL91_17490	COG0840	transmembrane signaling receptor activity
LGL91_17500	COG3121	Chaperone
LGL91_17515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGL91_17520	COG0706	membrane insertase activity
LGL91_17530	COG0594	ribonuclease P activity
LGL91_17535	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LGL91_17555	COG5433	transposase activity
LGL91_17565	COG3210	domain, Protein
LGL91_17570	COG1598	PFAM Uncharacterised protein family UPF0150
LGL91_17580	COG1192	Involved in chromosome partitioning
LGL91_17590	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL91_17595	COG0066	3-isopropylmalate dehydratase activity
LGL91_17615	COG1192	Involved in chromosome partitioning
LGL91_17625	COG3657	addiction module killer protein
LGL91_17710	COG1304	FMN binding
LGL91_17730	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL91_17735	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
LGL91_17780	COG2207	Transcriptional regulator
LGL91_17820	COG0840	transmembrane signaling receptor activity
LGL91_17835	COG3547	Transposase (IS116 IS110 IS902 family)
LGL91_17860	COG3657	addiction module killer protein
LGL91_17865	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL91_17880	COG3210	domain, Protein
LGL91_17990	COG3547	Transposase (IS116 IS110 IS902 family)
LGL91_18020	COG3718	enzyme involved in inositol metabolism
LGL91_18030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL91_18035	COG0673	inositol 2-dehydrogenase activity
LGL91_18040	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL91_18045	COG1129	ABC transporter
LGL91_18050	COG1879	ABC-type sugar transport system periplasmic component
LGL91_18055	COG0673	inositol 2-dehydrogenase activity
LGL91_18060	COG3962	Belongs to the TPP enzyme family
LGL91_18120	COG0625	glutathione transferase activity
LGL91_18125	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL91_18290	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL91_18295	COG2916	Histone family protein nucleoid-structuring protein H-NS