locus-tag	class	description
LGL88_00010	COG0592	DNA-directed DNA polymerase activity
LGL88_00020	COG0187	DNA topoisomerase II activity
LGL88_00025	COG0561	phosphatase activity
LGL88_00030	COG0823	Involved in the tonB-independent uptake of proteins
LGL88_00035	COG5645	(Lipo)protein
LGL88_00050	COG0569	domain protein
LGL88_00050	COG2985	domain, Protein
LGL88_00055	COG3977	Valine--pyruvate aminotransferase
LGL88_00060	COG2885	chlorophyll binding
LGL88_00080	COG2818	Glycosylase
LGL88_00130	COG2213	PTS system mannitol-specific
LGL88_00130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL88_00140	COG3722	fumarate hydratase activity
LGL88_00150	COG2258	MOSC domain
LGL88_00155	COG0840	transmembrane signaling receptor activity
LGL88_00160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL88_00175	COG0437	4 iron, 4 sulfur cluster binding
LGL88_00180	COG2864	formate dehydrogenase
LGL88_00190	COG1921	L-seryl-tRNASec selenium transferase activity
LGL88_00195	COG3276	selenocysteine insertion sequence binding
LGL88_00200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LGL88_00210	COG3274	enterobacterial common antigen metabolic process
LGL88_00220	COG0582	viral genome integration into host DNA
LGL88_00275	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL88_00285	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGL88_00290	COG2986	histidine ammonia-lyase
LGL88_00310	COG2194	sulfuric ester hydrolase activity
LGL88_00315	COG2197	response regulator
LGL88_00320	COG3851	Histidine kinase
LGL88_00325	COG2271	Major facilitator Superfamily
LGL88_00335	COG0747	negative chemotaxis
LGL88_00340	COG0601	transmembrane transport
LGL88_00345	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL88_00350	COG0444	Belongs to the ABC transporter superfamily
LGL88_00355	COG4608	Belongs to the ABC transporter superfamily
LGL88_00360	COG2194	sulfuric ester hydrolase activity
LGL88_00385	COG1215	transferase activity, transferring glycosyl groups
LGL88_00390	COG1215	transferase activity, transferring glycosyl groups
LGL88_00395	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGL88_00400	COG3118	belongs to the thioredoxin family
LGL88_00400	COG0457	Tetratricopeptide repeat
LGL88_00405	COG2200	EAL domain
LGL88_00405	COG2199	diguanylate cyclase activity
LGL88_00410	COG1301	dicarboxylic acid transport
LGL88_00415	COG0612	Peptidase, M16
LGL88_00420	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL88_00425	COG1942	4-Oxalocrotonate Tautomerase
LGL88_00430	COG2200	EAL domain
LGL88_00435	COG2134	cdp-diacylglycerol pyrophosphatase
LGL88_00440	COG1295	ribonuclease BN
LGL88_00450	COG1301	dicarboxylic acid transport
LGL88_00455	COG0626	cystathionine gamma-synthase activity
LGL88_00475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL88_00480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGL88_00485	COG0339	signal peptide processing
LGL88_00490	COG0742	ribosomal rna small subunit methyltransferase
LGL88_00500	COG0589	response to stress
LGL88_00510	COG0306	phosphate transporter
LGL88_00515	COG2081	HI0933 family
LGL88_00525	COG1247	-acetyltransferase
LGL88_00530	COG1741	Belongs to the pirin family
LGL88_00535	COG1609	Transcriptional regulator
LGL88_00540	COG2610	gluconate transmembrane transporter activity
LGL88_00545	COG3265	gluconokinase activity
LGL88_00550	COG2095	MarC family integral membrane protein
LGL88_00555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL88_00560	COG3275	phosphorelay sensor kinase activity
LGL88_00565	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGL88_00570	COG1523	belongs to the glycosyl hydrolase 13 family
LGL88_00575	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGL88_00580	COG0297	glycogen (starch) synthase activity
LGL88_00585	COG0058	SHG alpha-glucan phosphorylase activity
LGL88_00590	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL88_00595	COG1349	DNA-binding transcription factor activity
LGL88_00600	COG0705	Rhomboid family
LGL88_00610	COG2909	trisaccharide binding
LGL88_00615	COG0058	SHG alpha-glucan phosphorylase activity
LGL88_00620	COG1640	4-alpha-glucanotransferase
LGL88_00630	COG1040	competence protein
LGL88_00635	COG0596	Alpha beta hydrolase
LGL88_00655	COG1918	ferrous iron import across plasma membrane
LGL88_00660	COG2183	response to ionizing radiation
LGL88_00685	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL88_00700	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGL88_00710	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGL88_00715	COG1011	Hydrolase
LGL88_00725	COG0494	nUDIX hydrolase
LGL88_00730	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL88_00755	COG4796	Type ii and iii secretion system protein
LGL88_00760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL88_00780	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGL88_00790	COG0180	Tryptophanyl-tRNA synthetase
LGL88_00810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGL88_00815	COG0402	S-adenosylhomocysteine deaminase activity
LGL88_00820	COG0738	Major facilitator superfamily
LGL88_00835	COG1609	Transcriptional regulator
LGL88_00840	COG1486	melibiose metabolic process
LGL88_00845	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL88_00860	COG1289	transmembrane transporter activity
LGL88_00865	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL88_00870	COG1765	OsmC-like protein
LGL88_00895	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL88_00900	COG3954	Phosphoribulokinase
LGL88_00910	COG0429	hydrolase of the alpha beta-hydrolase fold
LGL88_00920	COG0859	PFAM glycosyl transferase family 9
LGL88_00925	COG1216	Glycosyl transferase, family 2
LGL88_00930	COG0488	(ABC) transporter
LGL88_00935	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL88_00945	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGL88_00950	COG1047	Peptidyl-prolyl cis-trans
LGL88_00960	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL88_00965	COG2964	Protein conserved in bacteria
LGL88_00975	COG2923	Belongs to the DsrF TusC family
LGL88_00980	COG2168	tRNA wobble position uridine thiolation
LGL88_00985	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGL88_00990	COG0049	tRNA binding
LGL88_01000	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGL88_01015	COG0051	transcription antitermination factor activity, RNA binding
LGL88_01020	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGL88_01030	COG0089	rRNA binding
LGL88_01035	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGL88_01040	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGL88_01045	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGL88_01055	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGL88_01060	COG0255	Belongs to the universal ribosomal protein uL29 family
LGL88_01065	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGL88_01070	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGL88_01080	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGL88_01105	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGL88_01110	COG1841	ribosomal large subunit assembly
LGL88_01115	COG0200	Binds to the 23S rRNA
LGL88_01120	COG0201	protein transport
LGL88_01125	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL88_01130	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGL88_01140	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGL88_01150	COG0203	ribosomal protein L17
LGL88_01155	COG0789	Transcriptional regulator
LGL88_01160	COG3036	rescue of stalled ribosome
LGL88_01165	COG1970	mechanosensitive ion channel activity
LGL88_01175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGL88_01175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGL88_01180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGL88_01185	COG0242	peptide deformylase activity
LGL88_01190	COG0758	DNA mediated transformation
LGL88_01195	COG2922	Belongs to the Smg family
LGL88_01200	COG0551	DNA topoisomerase type I activity
LGL88_01205	COG0009	L-threonylcarbamoyladenylate synthase
LGL88_01215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGL88_01240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGL88_01285	COG0250	Participates in transcription elongation, termination and antitermination
LGL88_01290	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGL88_01300	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGL88_01305	COG0222	ribosome binding
LGL88_01310	COG0085	RNA polymerase activity
LGL88_01315	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGL88_01325	COG2022	thiamine diphosphate biosynthetic process
LGL88_01330	COG2104	thiamine diphosphate biosynthetic process
LGL88_01335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL88_01350	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LGL88_01355	COG2816	NAD+ diphosphatase activity
LGL88_01360	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGL88_01365	COG1515	deoxyribonuclease V activity
LGL88_01385	COG0151	Belongs to the GarS family
LGL88_01390	COG0138	bifunctional purine biosynthesis protein purh
LGL88_01435	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGL88_01470	COG0583	DNA-binding transcription factor activity
LGL88_01550	COG1222	aaa ATPase
LGL88_01580	COG0527	aspartate kinase activity
LGL88_01590	COG3223	Belongs to the PsiE family
LGL88_01595	COG3833	ABC-type maltose transport systems, permease component
LGL88_01600	COG1175	transmembrane transport
LGL88_01605	COG2182	Extracellular solute-binding protein
LGL88_01620	COG4580	involved in the transport of maltose and maltodextrins
LGL88_01640	COG2937	Belongs to the GPAT DAPAT family
LGL88_01645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGL88_01650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGL88_01655	COG0735	belongs to the Fur family
LGL88_01660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL88_01670	COG0604	alcohol dehydrogenase
LGL88_01685	COG1448	Aminotransferase
LGL88_01690	COG2315	Protein conserved in bacteria
LGL88_01695	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGL88_01710	COG2252	PERMEase
LGL88_01715	COG0025	NhaP-type Na H and K H
LGL88_01720	COG0583	DNA-binding transcription factor activity
LGL88_01725	COG1380	Effector of murein hydrolase LrgA
LGL88_01730	COG1346	cytolysis
LGL88_01740	COG1560	Kdo2-lipid A biosynthetic process
LGL88_01750	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGL88_01755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL88_01760	COG2264	protein methyltransferase activity
LGL88_01765	COG4145	pantothenate transmembrane transporter activity
LGL88_01770	COG3924	membrane
LGL88_01775	COG0439	Biotin carboxylase
LGL88_01780	COG0511	ligase activity, forming carbon-carbon bonds
LGL88_01790	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LGL88_01795	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL88_01800	COG0604	alcohol dehydrogenase
LGL88_01805	COG2200	EAL domain
LGL88_01805	COG2199	diguanylate cyclase activity
LGL88_01810	COG1077	Cell shape determining protein MreB Mrl
LGL88_01815	COG1792	Involved in formation and maintenance of cell shape
LGL88_01820	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGL88_01825	COG0424	maF-like protein
LGL88_01835	COG3164	Protein of unknown function
LGL88_01840	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL88_01845	COG0312	modulator of DNA gyrase
LGL88_01850	COG0583	DNA-binding transcription factor activity
LGL88_01860	COG1566	PFAM secretion protein HlyD family protein
LGL88_01865	COG1289	transmembrane transporter activity
LGL88_01875	COG4290	ribonuclease
LGL88_01880	COG2732	(Barnase) inhibitor
LGL88_01885	COG3028	Belongs to the UPF0307 family
LGL88_01890	COG0312	modulator of DNA gyrase
LGL88_01895	COG3783	Cytochrome b(562)
LGL88_01900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL88_01910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGL88_01920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL88_01920	COG1263	PTS System
LGL88_01925	COG0366	Alpha amylase catalytic
LGL88_01935	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LGL88_01940	COG0540	Belongs to the ATCase OTCase family
LGL88_01945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL88_01965	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGL88_01970	COG1137	ATPase activity
LGL88_01975	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGL88_01980	COG3117	lipopolysaccharide transmembrane transporter activity
LGL88_01985	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGL88_01990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGL88_01990	COG0517	IMP dehydrogenase activity
LGL88_01995	COG0530	calcium, potassium:sodium antiporter activity
LGL88_02000	COG1127	ABC transporter
LGL88_02005	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL88_02010	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL88_02015	COG2854	intermembrane phospholipid transfer
LGL88_02020	COG3113	response to antibiotic
LGL88_02025	COG5007	Belongs to the BolA IbaG family
LGL88_02030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGL88_02040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL88_02045	COG3105	Protein conserved in bacteria
LGL88_02050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGL88_02055	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGL88_02060	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGL88_02065	COG0625	glutathione transferase activity
LGL88_02070	COG2969	positive regulation of protein catabolic process
LGL88_02080	COG0493	'glutamate synthase
LGL88_02085	COG0070	glutamate synthase
LGL88_02085	COG0067	glutamate synthase
LGL88_02085	COG0069	glutamate synthase activity
LGL88_02090	COG1242	4 iron, 4 sulfur cluster binding
LGL88_02095	COG0784	Response regulator, receiver
LGL88_02095	COG2198	Histidine kinase
LGL88_02095	COG5002	protein histidine kinase activity
LGL88_02100	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LGL88_02105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL88_02110	COG2823	Periplasmic or secreted lipoprotein
LGL88_02115	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL88_02130	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGL88_02145	COG1741	Belongs to the pirin family
LGL88_02150	COG0583	DNA-binding transcription factor activity
LGL88_02155	COG2259	Doxx family
LGL88_02165	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LGL88_02170	COG4575	ribosome binding
LGL88_02185	COG0586	Pfam SNARE associated Golgi protein
LGL88_02200	COG2271	Major facilitator Superfamily
LGL88_02215	COG2721	sulfolactate sulfo-lyase activity
LGL88_02225	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LGL88_02230	COG0861	Integral membrane protein TerC family
LGL88_02235	COG0673	inositol 2-dehydrogenase activity
LGL88_02240	COG1451	nucleotide metabolic process
LGL88_02255	COG1902	pentaerythritol trinitrate reductase activity
LGL88_02255	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGL88_02260	COG2831	hemolysin activation secretion protein
LGL88_02265	COG3210	domain, Protein
LGL88_02305	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL88_02320	COG1028	Short-chain dehydrogenase reductase Sdr
LGL88_02345	COG3550	peptidyl-serine autophosphorylation
LGL88_02375	COG0358	DNA primase activity
LGL88_02380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGL88_02385	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGL88_02390	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGL88_02395	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGL88_02400	COG1968	undecaprenyl-diphosphatase activity
LGL88_02405	COG0617	tRNA 3'-terminal CCA addition
LGL88_02410	COG4991	sh3 domain protein
LGL88_02415	COG3025	triphosphatase activity
LGL88_02425	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LGL88_02425	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGL88_02440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGL88_02445	COG3384	dioxygenase
LGL88_02450	COG0754	glutathionylspermidine amidase activity
LGL88_02455	COG5463	Belongs to the UPF0441 family
LGL88_02460	COG1538	Outer membrane efflux protein
LGL88_02465	COG0494	nUDIX hydrolase
LGL88_02470	COG3151	Protein conserved in bacteria
LGL88_02475	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGL88_02480	COG3150	esterase
LGL88_02485	COG0187	DNA topoisomerase II activity
LGL88_02490	COG0583	DNA-binding transcription factor activity
LGL88_02495	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL88_02500	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LGL88_02510	COG2132	Multicopper oxidase
LGL88_02520	COG0656	L-ascorbic acid biosynthetic process
LGL88_02525	COG1979	alcohol dehydrogenase
LGL88_02530	COG2207	Transcriptional regulator
LGL88_02535	COG0586	Pfam SNARE associated Golgi protein
LGL88_02540	COG0626	cystathionine gamma-synthase activity
LGL88_02545	COG0811	peptide transport
LGL88_02550	COG0848	biopolymer transport protein
LGL88_02605	COG4964	Belongs to the GSP D family
LGL88_02630	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGL88_02635	COG4774	siderophore transport
LGL88_02645	COG3251	PFAM MbtH domain protein
LGL88_02650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGL88_02660	COG1120	ATPase activity
LGL88_02665	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL88_02670	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL88_02680	COG4592	Periplasmic binding protein
LGL88_02685	COG1169	isochorismate synthase
LGL88_02690	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGL88_02695	COG3433	isochorismatase activity
LGL88_02695	COG1535	isochorismatase
LGL88_02700	COG1028	Short-chain dehydrogenase reductase Sdr
LGL88_02715	COG0814	amino acid
LGL88_02720	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGL88_02725	COG1882	Formate acetyltransferase
LGL88_02730	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL88_02740	COG1349	DNA-binding transcription factor activity
LGL88_02745	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL88_02750	COG1028	Short-chain dehydrogenase reductase Sdr
LGL88_02755	COG3731	PTS system glucitol sorbitol-specific IIA component
LGL88_02760	COG3732	PTS system glucitol sorbitol-specific
LGL88_02765	COG3730	PTS system glucitol sorbitol-specific
LGL88_02780	COG0583	DNA-binding transcription factor activity
LGL88_02855	COG0741	lytic transglycosylase activity
LGL88_02860	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LGL88_02865	COG1194	a g-specific adenine glycosylase
LGL88_02875	COG3171	Protein conserved in bacteria
LGL88_02890	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL88_02895	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGL88_02900	COG1872	DUF167
LGL88_02905	COG0762	integral membrane protein
LGL88_02910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGL88_02915	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGL88_02920	COG2805	Type II/IV secretion system protein
LGL88_02930	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL88_02935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGL88_02940	COG1678	Uncharacterized ACR, COG1678
LGL88_02945	COG0189	ligase activity
LGL88_02950	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGL88_02955	COG2356	endonuclease I
LGL88_02960	COG3091	SprT-like family
LGL88_02965	COG0640	Transcriptional regulator
LGL88_02980	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGL88_02985	COG1166	arginine decarboxylase activity
LGL88_02995	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGL88_03000	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGL88_03005	COG0126	phosphoglycerate kinase activity
LGL88_03010	COG0191	fructose-bisphosphate aldolase activity
LGL88_03020	COG1279	arginine transmembrane transporter activity
LGL88_03035	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGL88_03040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL88_03045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGL88_03055	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGL88_03065	COG0006	proline dipeptidase activity
LGL88_03070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL88_03075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL88_03080	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGL88_03100	COG1272	protein, Hemolysin III
LGL88_03110	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGL88_03120	COG0716	FMN binding
LGL88_03125	COG4974	Belongs to the 'phage' integrase family
LGL88_03130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL88_03135	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGL88_03145	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGL88_03155	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL88_03160	COG1127	ABC transporter
LGL88_03190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL88_03200	COG2165	general secretion pathway protein
LGL88_03255	COG0583	DNA-binding transcription factor activity
LGL88_03260	COG0583	DNA-binding transcription factor activity
LGL88_03270	COG1609	Transcriptional regulator
LGL88_03275	COG0318	PFAM AMP-dependent synthetase and ligase
LGL88_03275	COG0204	Acyl-transferase
LGL88_03280	COG0477	Major facilitator Superfamily
LGL88_03285	COG0667	Aldo Keto reductase
LGL88_03290	COG0861	Integral membrane protein TerC family
LGL88_03295	COG3066	DNA modification
LGL88_03305	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LGL88_03310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGL88_03335	COG4967	type IV pilus modification protein PilV
LGL88_03340	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGL88_03345	COG1025	Belongs to the peptidase M16 family
LGL88_03350	COG1074	ATP-dependent DNA helicase activity
LGL88_03355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL88_03360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LGL88_03360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL88_03365	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL88_03385	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LGL88_03390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGL88_03395	COG2166	iron-sulfur cluster assembly
LGL88_03400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGL88_03410	COG0583	DNA-binding transcription factor activity
LGL88_03415	COG2363	Small membrane protein
LGL88_03420	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LGL88_03430	COG1611	Belongs to the LOG family
LGL88_03445	COG3098	single-species biofilm formation
LGL88_03450	COG0564	pseudouridine synthase activity
LGL88_03465	COG2171	N-acyltransferase activity
LGL88_03470	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LGL88_03485	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGL88_03490	COG0528	UMP kinase activity
LGL88_03510	COG0575	Belongs to the CDS family
LGL88_03515	COG0750	zinc metalloprotease
LGL88_03525	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LGL88_03530	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL88_03550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGL88_03555	COG0587	DNA-directed DNA polymerase activity
LGL88_03560	COG0825	malonyl-CoA metabolic process
LGL88_03575	COG0346	lactoylglutathione lyase activity
LGL88_03590	COG4568	rho-dependent transcription termination
LGL88_03600	COG4681	YaeQ
LGL88_03610	COG3015	lipoprotein NlpE involved in copper resistance
LGL88_03615	COG0442	prolyl-tRNA aminoacylation
LGL88_03620	COG1720	tRNA m6t6A37 methyltransferase activity
LGL88_03630	COG1464	Belongs to the NlpA lipoprotein family
LGL88_03635	COG2011	ABC-type metal ion transport system permease component
LGL88_03645	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL88_03670	COG5544	Lipoprotein
LGL88_03675	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL88_03680	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL88_03680	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL88_03680	COG1042	CoA-binding domain protein
LGL88_03685	COG3148	PFAM DTW domain containing protein
LGL88_03690	COG3118	belongs to the thioredoxin family
LGL88_03695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL88_03700	COG2814	Major facilitator Superfamily
LGL88_03705	COG1566	PFAM secretion protein HlyD family protein
LGL88_03715	COG1846	Transcriptional regulator
LGL88_03720	COG2814	Major facilitator Superfamily
LGL88_03730	COG2113	Glycine betaine
LGL88_03735	COG4176	ABC-type proline glycine betaine transport system permease component
LGL88_03740	COG4175	Glycine betaine
LGL88_03750	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL88_03755	COG1780	Probably involved in ribonucleotide reductase function
LGL88_03785	COG1278	Cold shock
LGL88_03790	COG0579	oxidoreductase
LGL88_03795	COG1304	FMN binding
LGL88_03800	COG1620	l-lactate permease
LGL88_03825	COG1129	ABC transporter
LGL88_03830	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL88_03840	COG1069	ribulokinase activity
LGL88_03905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL88_03940	COG0582	viral genome integration into host DNA
LGL88_03950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGL88_03955	COG2867	negative regulation of translational initiation
LGL88_03965	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL88_03970	COG0497	DNA recombination
LGL88_03975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGL88_03980	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGL88_03990	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LGL88_04005	COG0513	Belongs to the DEAD box helicase family
LGL88_04015	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGL88_04025	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LGL88_04035	COG3086	response to oxidative stress
LGL88_04040	COG0481	GTPase activity
LGL88_04055	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGL88_04065	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGL88_04075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL88_04080	COG1737	Transcriptional regulator
LGL88_04090	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL88_04090	COG1263	PTS System
LGL88_04095	COG0560	Phosphoserine phosphatase
LGL88_04105	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LGL88_04120	COG2205	protein histidine kinase activity
LGL88_04125	COG3170	Tfp pilus assembly protein FimV
LGL88_04130	COG2204	response regulator
LGL88_04135	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL88_04135	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL88_04140	COG0347	Belongs to the P(II) protein family
LGL88_04155	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LGL88_04160	COG3457	Alanine racemase
LGL88_04170	COG2188	Transcriptional regulator
LGL88_04175	COG1017	nitric oxide dioxygenase activity
LGL88_04175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL88_04185	COG2814	Major facilitator Superfamily
LGL88_04190	COG3711	transcriptional antiterminator
LGL88_04195	COG3683	transport system, periplasmic component
LGL88_04200	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL88_04210	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LGL88_04215	COG1959	2 iron, 2 sulfur cluster binding
LGL88_04225	COG0822	iron-sulfur transferase activity
LGL88_04240	COG0443	Heat shock 70 kDa protein
LGL88_04245	COG0633	Ferredoxin
LGL88_04250	COG2975	iron-sulfur cluster assembly
LGL88_04265	COG2373	Large extracellular alpha-helical protein
LGL88_04270	COG4953	penicillin-binding protein 1C
LGL88_04285	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGL88_04305	COG0124	histidyl-tRNA synthetase
LGL88_04310	COG2976	Protein conserved in bacteria
LGL88_04315	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL88_04325	COG1645	bacterial-type flagellum-dependent swarming motility
LGL88_04330	COG1570	exodeoxyribonuclease VII activity
LGL88_04335	COG0517	IMP dehydrogenase activity
LGL88_04335	COG0516	GMP reductase activity
LGL88_04340	COG0519	Catalyzes the synthesis of GMP from XMP
LGL88_04340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGL88_04350	COG0351	phosphomethylpyrimidine kinase
LGL88_04365	COG1597	lipid kinase activity
LGL88_04370	COG0826	peptidase U32
LGL88_04375	COG3422	double-strand break repair
LGL88_04380	COG0745	RESPONSE REGULATOR receiver
LGL88_04385	COG2205	protein histidine kinase activity
LGL88_04390	COG0477	Major facilitator Superfamily
LGL88_04395	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL88_04405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL88_04425	COG3121	Chaperone
LGL88_04435	COG0443	Heat shock 70 kDa protein
LGL88_04440	COG2239	Acts as a magnesium transporter
LGL88_04455	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGL88_04460	COG0573	inorganic phosphate transmembrane transporter activity
LGL88_04465	COG0581	inorganic phosphate transmembrane transporter activity
LGL88_04475	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL88_04480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGL88_04485	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGL88_04490	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGL88_04495	COG2233	PERMEase
LGL88_04500	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGL88_04505	COG1393	Belongs to the ArsC family
LGL88_04510	COG4783	chaperone-mediated protein folding
LGL88_04515	COG0628	permease
LGL88_04520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGL88_04525	COG2716	regulation of RNA biosynthetic process
LGL88_04530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL88_04535	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LGL88_04555	COG0400	carboxylic ester hydrolase activity
LGL88_04565	COG1876	peptidase activity
LGL88_04570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGL88_04575	COG1393	Belongs to the ArsC family
LGL88_04580	COG1605	Chorismate mutase
LGL88_04590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL88_04600	COG2197	response regulator
LGL88_04605	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL88_04605	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL88_04610	COG3062	negative regulation of establishment of protein localization
LGL88_04615	COG0243	molybdopterin cofactor binding
LGL88_04620	COG3043	anaerobic respiration
LGL88_04625	COG3005	denitrification pathway
LGL88_04630	COG0494	nUDIX hydrolase
LGL88_04635	COG0281	malic enzyme
LGL88_04635	COG0280	phosphate acetyltransferase
LGL88_04640	COG1671	Belongs to the UPF0178 family
LGL88_04670	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL88_04675	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL88_04680	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL88_04750	COG3111	PFAM Bacterial OB fold (BOF) protein
LGL88_04760	COG2837	iron assimilation
LGL88_04765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL88_04780	COG2731	YhcH YjgK YiaL family protein
LGL88_04785	COG1737	Transcriptional regulator
LGL88_04795	COG4150	thiosulfate binding
LGL88_04800	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGL88_04805	COG4208	sulfate ABC transporter
LGL88_04815	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL88_04830	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL88_04840	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LGL88_04850	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL88_04855	COG3530	Putative quorum-sensing-regulated virulence factor
LGL88_04925	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL88_04930	COG1914	H( )-stimulated, divalent metal cation uptake system
LGL88_04950	COG0837	glucose binding
LGL88_04955	COG2223	nitrite transmembrane transporter activity
LGL88_04960	COG3279	Response regulator of the LytR AlgR family
LGL88_04965	COG3275	phosphorelay sensor kinase activity
LGL88_04975	COG0436	Aminotransferase
LGL88_04980	COG3038	cytochrome b561
LGL88_04990	COG1598	PFAM Uncharacterised protein family UPF0150
LGL88_04995	COG2951	lytic endotransglycosylase activity
LGL88_05000	COG2824	Alkylphosphonate utilization operon protein PhnA
LGL88_05060	COG0582	viral genome integration into host DNA
LGL88_05075	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL88_05080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL88_05085	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL88_05090	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LGL88_05095	COG1138	Cytochrome C-type biogenesis protein
LGL88_05100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL88_05105	COG3088	subunit of a heme lyase
LGL88_05105	COG4235	cytochrome complex assembly
LGL88_05110	COG3088	subunit of a heme lyase
LGL88_05110	COG4235	cytochrome complex assembly
LGL88_05125	COG3691	Protein conserved in bacteria
LGL88_05130	COG0183	Belongs to the thiolase family
LGL88_05135	COG1024	Enoyl-CoA hydratase
LGL88_05135	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL88_05140	COG2062	phosphohistidine phosphatase, SixA
LGL88_05145	COG2840	Smr protein MutS2
LGL88_05150	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL88_05160	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LGL88_05165	COG0730	response to heat
LGL88_05170	COG3101	peptidyl-lysine hydroxylation
LGL88_05185	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL88_05215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL88_05220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL88_05245	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL88_05255	COG0586	Pfam SNARE associated Golgi protein
LGL88_05265	COG0285	dihydrofolate synthase activity
LGL88_05270	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LGL88_05275	COG1286	toxin biosynthetic process
LGL88_05280	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGL88_05285	COG0163	prenyltransferase activity
LGL88_05300	COG4215	(ABC) transporter
LGL88_05305	COG4160	amino acid transport
LGL88_05315	COG1090	epimerase
LGL88_05320	COG0625	glutathione transferase activity
LGL88_05330	COG0622	Phosphoesterase
LGL88_05335	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LGL88_05340	COG3037	sugar-specific permease SgaT UlaA
LGL88_05355	COG1609	Transcriptional regulator
LGL88_05360	COG0857	belongs to the CobB CobQ family
LGL88_05360	COG0280	phosphate acetyltransferase
LGL88_05370	COG3092	negative regulation of chromosome organization
LGL88_05375	COG3013	Belongs to the UPF0304 family
LGL88_05385	COG0471	metal ion transport
LGL88_05385	COG0490	domain, Protein
LGL88_05390	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL88_05395	COG0436	Aminotransferase
LGL88_05400	COG0583	DNA-binding transcription factor activity
LGL88_05405	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL88_05410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL88_05430	COG1034	ATP synthesis coupled electron transport
LGL88_05435	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGL88_05440	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL88_05445	COG0839	Belongs to the complex I subunit 6 family
LGL88_05455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGL88_05460	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL88_05475	COG4575	ribosome binding
LGL88_05480	COG1169	isochorismate synthase
LGL88_05485	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGL88_05490	COG0596	Alpha beta hydrolase
LGL88_05495	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGL88_05520	COG0814	amino acid
LGL88_05535	COG2246	polysaccharide biosynthetic process
LGL88_05545	COG4574	serine-type endopeptidase inhibitor activity
LGL88_05555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL88_05565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL88_05570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL88_05580	COG2205	protein histidine kinase activity
LGL88_05580	COG0784	Response regulator, receiver
LGL88_05590	COG2198	Histidine kinase
LGL88_05590	COG0642	Histidine kinase
LGL88_05595	COG2223	nitrite transmembrane transporter activity
LGL88_05615	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL88_05620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGL88_05670	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL88_05675	COG5532	Uncharacterized conserved protein (DUF2303)
LGL88_05720	COG4626	Terminase
LGL88_05720	COG1802	Transcriptional regulator
LGL88_05725	COG4725	Belongs to the MT-A70-like family
LGL88_05745	COG1403	HNH endonuclease
LGL88_05820	COG0616	signal peptide processing
LGL88_05860	COG4386	tail sheath protein
LGL88_05905	COG3299	homolog of phage Mu protein gp47
LGL88_05930	COG3083	sulfuric ester hydrolase activity
LGL88_05935	COG3082	Protein of unknown function (DUF1414)
LGL88_05950	COG1061	Type III restriction enzyme res subunit
LGL88_05955	COG1187	pseudouridine synthase activity
LGL88_05960	COG2814	Major facilitator Superfamily
LGL88_05970	COG4172	Belongs to the ABC transporter superfamily
LGL88_05975	COG4239	(ABC) transporter, permease
LGL88_05980	COG4174	ABC transporter (Permease)
LGL88_05985	COG4166	transmembrane transport
LGL88_05990	COG2200	EAL domain
LGL88_05995	COG0791	NLP P60 protein
LGL88_06000	COG0671	phosphoesterase, PA-phosphatase related
LGL88_06005	COG0523	cobalamin synthesis protein
LGL88_06015	COG0246	Mannitol dehydrogenase
LGL88_06025	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGL88_06040	COG0243	molybdopterin cofactor binding
LGL88_06045	COG3005	denitrification pathway
LGL88_06060	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL88_06065	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGL88_06065	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL88_06065	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL88_06070	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGL88_06075	COG2855	membrane
LGL88_06085	COG0583	DNA-binding transcription factor activity
LGL88_06090	COG0833	amino acid
LGL88_06100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL88_06110	COG4771	TonB-dependent receptor
LGL88_06115	COG0531	amino acid
LGL88_06120	COG2925	Exonuclease
LGL88_06125	COG3320	Male sterility
LGL88_06125	COG1022	Amp-dependent synthetase and ligase
LGL88_06130	COG1289	transmembrane transporter activity
LGL88_06150	COG3842	ATPase activity
LGL88_06160	COG1840	ABC-type Fe3 transport system, periplasmic component
LGL88_06165	COG2271	Major facilitator Superfamily
LGL88_06180	COG4565	transcriptional regulatory protein
LGL88_06185	COG3290	protein histidine kinase activity
LGL88_06190	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LGL88_06195	COG3052	prosthetic group binding
LGL88_06200	COG2301	Belongs to the HpcH HpaI aldolase family
LGL88_06205	COG3051	citrate lyase alpha subunit
LGL88_06220	COG0471	metal ion transport
LGL88_06345	COG1674	ftsk spoiiie
LGL88_06345	COG1178	ABC-type Fe3 transport system permease component
LGL88_06395	COG0675	Transposase, IS605 OrfB family
LGL88_06410	COG3772	lysozyme
LGL88_06550	COG3321	synthase
LGL88_06550	COG1028	Short-chain dehydrogenase reductase Sdr
LGL88_06550	COG0604	alcohol dehydrogenase
LGL88_06560	COG1609	Transcriptional regulator
LGL88_06580	COG0840	transmembrane signaling receptor activity
LGL88_06585	COG1285	pathogenesis
LGL88_06595	COG0589	response to stress
LGL88_06615	COG1360	Flagellar Motor Protein
LGL88_06620	COG0643	Histidine kinase
LGL88_06620	COG2198	Histidine kinase
LGL88_06625	COG0835	chemotaxis
LGL88_06630	COG0840	transmembrane signaling receptor activity
LGL88_06635	COG0840	transmembrane signaling receptor activity
LGL88_06640	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGL88_06650	COG0745	RESPONSE REGULATOR receiver
LGL88_06655	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LGL88_06660	COG4935	Belongs to the peptidase S8 family
LGL88_06660	COG1404	Belongs to the peptidase S8 family
LGL88_06665	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL88_06670	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL88_06680	COG3418	PFAM FlgN family protein
LGL88_06685	COG2747	anti-sigma28 factor FlgM
LGL88_06695	COG1815	bacterial-type flagellum-dependent cell motility
LGL88_06700	COG1558	bacterial-type flagellum-dependent cell motility
LGL88_06780	COG1580	Controls the rotational direction of flagella during chemotaxis
LGL88_06795	COG1157	protein secretion by the type III secretion system
LGL88_06805	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGL88_06815	COG1677	Flagellar hook-basal body complex protein FliE
LGL88_06825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL88_06830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGL88_06870	COG1191	sigma factor activity
LGL88_06880	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGL88_06885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL88_06890	COG0765	amino acid transport
LGL88_06895	COG1126	abc transporter atp-binding protein
LGL88_06900	COG0506	proline dehydrogenase activity
LGL88_06900	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL88_06900	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL88_06905	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL88_06910	COG3710	Transcriptional regulator
LGL88_06915	COG0531	amino acid
LGL88_06925	COG1113	amino acid transport
LGL88_06950	COG2197	response regulator
LGL88_06955	COG0322	excinuclease ABC activity
LGL88_06960	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGL88_06985	COG2801	Transposase and inactivated derivatives
LGL88_06990	COG0840	transmembrane signaling receptor activity
LGL88_07025	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGL88_07030	COG2153	protein acetylation
LGL88_07065	COG0531	amino acid
LGL88_07070	COG0076	glutamate decarboxylase activity
LGL88_07085	COG2235	arginine
LGL88_07100	COG1757	Na H antiporter
LGL88_07115	COG1187	pseudouridine synthase activity
LGL88_07120	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL88_07125	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL88_07130	COG2723	6-phospho-beta-galactosidase activity
LGL88_07135	COG1447	Phosphotransferase system cellobiose-specific component IIA
LGL88_07140	COG2169	Transcriptional regulator
LGL88_07140	COG1917	Cupin 2, conserved barrel domain protein
LGL88_07155	COG1278	Cold shock
LGL88_07160	COG1278	Cold shock
LGL88_07180	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGL88_07200	COG3706	GGDEF domain
LGL88_07200	COG5001	Diguanylate cyclase
LGL88_07200	COG4251	negative regulation of phosphorylation
LGL88_07200	COG2203	Gaf domain
LGL88_07210	COG1132	(ABC) transporter
LGL88_07230	COG2207	Transcriptional regulator
LGL88_07265	COG1113	amino acid transport
LGL88_07285	COG1496	oxidoreductase activity
LGL88_07290	COG0768	penicillin binding
LGL88_07295	COG2226	methyltransferase
LGL88_07325	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGL88_07335	COG1960	acyl-CoA dehydrogenase activity
LGL88_07355	COG1971	Probably functions as a manganese efflux pump
LGL88_07360	COG4811	Protein of unknown function (DUF986)
LGL88_07365	COG3716	PTS system mannose fructose sorbose family IID component
LGL88_07370	COG3715	PTS system
LGL88_07375	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL88_07375	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL88_07380	COG1253	flavin adenine dinucleotide binding
LGL88_07385	COG1760	l-serine dehydratase
LGL88_07390	COG0494	nUDIX hydrolase
LGL88_07410	COG0513	Belongs to the DEAD box helicase family
LGL88_07415	COG3141	response to X-ray
LGL88_07420	COG3097	Belongs to the UPF0267 family
LGL88_07430	COG1770	oligopeptidase
LGL88_07435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL88_07450	COG1528	Iron-storage protein
LGL88_07455	COG2372	response to copper ion
LGL88_07460	COG1276	copper resistance
LGL88_07470	COG4974	Belongs to the 'phage' integrase family
LGL88_07515	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LGL88_07625	COG4695	Portal protein
LGL88_07755	COG5001	Diguanylate cyclase
LGL88_07755	COG2203	Gaf domain
LGL88_07755	COG4251	negative regulation of phosphorylation
LGL88_07755	COG3706	GGDEF domain
LGL88_07760	COG3008	intermembrane lipid transfer
LGL88_07765	COG2995	paraquat-inducible protein a
LGL88_07770	COG1956	GAF domain-containing protein
LGL88_07780	COG0793	Belongs to the peptidase S41A family
LGL88_07785	COG0501	Belongs to the peptidase M48B family
LGL88_07795	COG2814	Major facilitator Superfamily
LGL88_07805	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL88_07810	COG1823	symporter activity
LGL88_07815	COG1988	membrane-bound metal-dependent
LGL88_07820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL88_07830	COG3001	Fructosamine kinase
LGL88_07835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL88_07840	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL88_07845	COG1121	(ABC) transporter
LGL88_07850	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGL88_07925	COG0776	regulation of translation
LGL88_07950	COG2184	nucleotidyltransferase activity
LGL88_07965	COG4974	Belongs to the 'phage' integrase family
LGL88_07970	COG4139	cobalamin transport
LGL88_07980	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL88_07985	COG0463	Glycosyl transferase, family 2
LGL88_08000	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGL88_08005	COG2076	Multidrug Resistance protein
LGL88_08010	COG2076	Multidrug Resistance protein
LGL88_08015	COG0791	NLP P60 protein
LGL88_08020	COG0095	Lipoate-protein ligase
LGL88_08030	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LGL88_08035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL88_08040	COG4558	Periplasmic binding protein
LGL88_08045	COG3720	iron ion transport
LGL88_08050	COG4771	TonB-dependent receptor
LGL88_08060	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL88_08065	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGL88_08070	COG0574	Belongs to the PEP-utilizing enzyme family
LGL88_08070	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL88_08080	COG0628	permease
LGL88_08085	COG0277	FAD linked oxidase domain protein
LGL88_08085	COG0247	lactate metabolic process
LGL88_08090	COG2050	protein possibly involved in aromatic compounds catabolism
LGL88_08095	COG0316	Belongs to the HesB IscA family
LGL88_08100	COG0719	Fe-S assembly protein
LGL88_08105	COG0396	ATPase activity
LGL88_08110	COG0719	Fe-S assembly protein
LGL88_08120	COG2166	iron-sulfur cluster assembly
LGL88_08125	COG1388	LysM domain
LGL88_08125	COG1376	ErfK ybiS ycfS ynhG family protein
LGL88_08160	COG0307	riboflavin synthase, alpha
LGL88_08165	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL88_08170	COG2814	Major facilitator Superfamily
LGL88_08175	COG0583	DNA-binding transcription factor activity
LGL88_08180	COG1609	Transcriptional regulator
LGL88_08190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL88_08195	COG0791	NLP P60 protein
LGL88_08200	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGL88_08215	COG1902	pentaerythritol trinitrate reductase activity
LGL88_08220	COG1309	transcriptional regulator
LGL88_08225	COG2194	sulfuric ester hydrolase activity
LGL88_08230	COG3313	Fe-S protein
LGL88_08235	COG4989	oxidoreductase activity
LGL88_08245	COG1846	Transcriptional regulator
LGL88_08250	COG3133	Outer membrane lipoprotein
LGL88_08255	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGL88_08300	COG0484	heat shock protein binding
LGL88_08310	COG3104	oligopeptide transport
LGL88_08320	COG4172	Belongs to the ABC transporter superfamily
LGL88_08325	COG4172	Belongs to the ABC transporter superfamily
LGL88_08330	COG4171	peptide transport system, permease
LGL88_08340	COG4166	transmembrane transport
LGL88_08355	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LGL88_08360	COG1842	Phage shock protein A
LGL88_08370	COG1983	PspC domain protein
LGL88_08380	COG3106	COG3106 Predicted ATPase
LGL88_08385	COG3768	UPF0283 membrane protein
LGL88_08390	COG5654	RES domain protein
LGL88_08395	COG5642	Protein of unknown function (DUF2384)
LGL88_08405	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGL88_08410	COG4948	Mandelate Racemase Muconate Lactonizing
LGL88_08415	COG2866	Carboxypeptidase
LGL88_08420	COG4166	transmembrane transport
LGL88_08435	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL88_08435	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGL88_08435	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGL88_08435	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGL88_08445	COG1285	pathogenesis
LGL88_08450	COG3042	response to heat
LGL88_08455	COG3187	Heat shock protein
LGL88_08460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGL88_08465	COG2911	Protein conserved in bacteria
LGL88_08480	COG3784	Protein of unknown function (DUF1318)
LGL88_08485	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGL88_08490	COG1643	Atp-dependent helicase
LGL88_08495	COG3591	Belongs to the peptidase S1B family
LGL88_08505	COG1881	PFAM PEBP family protein
LGL88_08510	COG2207	Transcriptional regulator
LGL88_08525	COG2205	protein histidine kinase activity
LGL88_08530	COG0745	RESPONSE REGULATOR receiver
LGL88_08540	COG0531	amino acid
LGL88_08550	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LGL88_08555	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LGL88_08560	COG3623	hexulose-6-phosphate isomerase
LGL88_08565	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGL88_08595	COG0589	response to stress
LGL88_08600	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL88_08605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGL88_08610	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGL88_08620	COG1011	Hydrolase
LGL88_08660	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL88_08675	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL88_08680	COG4221	oxidoreductase activity
LGL88_08685	COG1742	UPF0060 membrane protein
LGL88_08705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGL88_08710	COG1940	carbohydrate kinase activity
LGL88_08735	COG0114	fumarate hydratase activity
LGL88_08740	COG1482	cell wall glycoprotein biosynthetic process
LGL88_08745	COG5339	Protein conserved in bacteria
LGL88_08765	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGL88_08770	COG0385	Bile acid
LGL88_08775	COG0673	inositol 2-dehydrogenase activity
LGL88_08785	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGL88_08795	COG4657	Part of a membrane complex involved in electron transport
LGL88_08810	COG3708	Transcriptional regulator
LGL88_08810	COG2207	Transcriptional regulator
LGL88_08820	COG4659	FMN binding
LGL88_08830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGL88_08835	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LGL88_08840	COG5002	protein histidine kinase activity
LGL88_08840	COG5001	Diguanylate cyclase
LGL88_08840	COG3447	MASE1 domain protein
LGL88_08845	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL88_08855	COG0023	Translation Initiation Factor
LGL88_08915	COG0463	Glycosyl transferase, family 2
LGL88_08955	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LGL88_08960	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LGL88_08965	COG0671	phosphoesterase, PA-phosphatase related
LGL88_08975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGL88_08995	COG0583	DNA-binding transcription factor activity
LGL88_09010	COG0616	signal peptide processing
LGL88_09015	COG1028	Short-chain dehydrogenase reductase Sdr
LGL88_09025	COG1187	pseudouridine synthase activity
LGL88_09030	COG0009	L-threonylcarbamoyladenylate synthase
LGL88_09035	COG0613	PHP domain protein
LGL88_09045	COG0512	Glutamine amidotransferase of anthranilate synthase
LGL88_09055	COG0135	phosphoribosylanthranilate isomerase activity
LGL88_09055	COG0134	indole-3-glycerol-phosphate synthase activity
LGL88_09060	COG0133	tryptophan synthase activity
LGL88_09075	COG3047	cAMP biosynthetic process
LGL88_09080	COG0727	PFAM Uncharacterised protein family (UPF0153)
LGL88_09105	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LGL88_09140	COG3710	Transcriptional regulator
LGL88_09155	COG2350	Protein conserved in bacteria
LGL88_09175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL88_09180	COG3099	Belongs to the UPF0263 family
LGL88_09195	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL88_09210	COG4166	transmembrane transport
LGL88_09215	COG2095	MarC family integral membrane protein
LGL88_09220	COG1454	alcohol dehydrogenase
LGL88_09220	COG1012	belongs to the aldehyde dehydrogenase family
LGL88_09240	COG0745	RESPONSE REGULATOR receiver
LGL88_09245	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGL88_09255	COG0788	formyltetrahydrofolate deformylase activity
LGL88_09285	COG0708	Exodeoxyribonuclease III
LGL88_09290	COG0494	nUDIX hydrolase
LGL88_09300	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL88_09310	COG0778	Nitroreductase
LGL88_09315	COG0616	signal peptide processing
LGL88_09320	COG0252	asparaginase activity
LGL88_09325	COG1335	isochorismatase
LGL88_09330	COG3139	Protein of unknown function (DUF1315)
LGL88_09335	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL88_09350	COG2194	sulfuric ester hydrolase activity
LGL88_09355	COG3713	MltA-interacting MipA family protein
LGL88_09365	COG2766	serine protein kinase
LGL88_09370	COG2718	Belongs to the UPF0229 family
LGL88_09390	COG2202	Pas domain
LGL88_09390	COG2200	EAL domain
LGL88_09390	COG2199	diguanylate cyclase activity
LGL88_09400	COG2814	Major facilitator Superfamily
LGL88_09405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGL88_09410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGL88_09415	COG2719	SpoVR family
LGL88_09425	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL88_09445	COG2983	Belongs to the UPF0260 family
LGL88_09450	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGL88_09455	COG3100	YcgL domain-containing protein
LGL88_09460	COG0850	regulation of cytokinetic process
LGL88_09465	COG2894	cell division
LGL88_09470	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LGL88_09475	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LGL88_09480	COG0318	PFAM AMP-dependent synthetase and ligase
LGL88_09485	COG3065	identical protein binding
LGL88_09490	COG1214	PFAM Peptidase M22, glycoprotease
LGL88_09495	COG1199	ATP-dependent helicase activity
LGL88_09500	COG0251	oxidation-reduction process
LGL88_09505	COG2076	Multidrug Resistance protein
LGL88_09515	COG0800	Aldolase
LGL88_09520	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGL88_09525	COG1737	Transcriptional regulator
LGL88_09530	COG0469	pyruvate kinase activity
LGL88_09535	COG1560	Kdo2-lipid A biosynthetic process
LGL88_09540	COG0739	heme binding
LGL88_09545	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LGL88_09550	COG1121	(ABC) transporter
LGL88_09555	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL88_09560	COG3104	oligopeptide transport
LGL88_09565	COG2255	four-way junction helicase activity
LGL88_09575	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LGL88_09585	COG0494	nUDIX hydrolase
LGL88_09590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGL88_09600	COG1801	Protein of unknown function DUF72
LGL88_09605	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LGL88_09620	COG3142	Participates in the control of copper homeostasis
LGL88_09625	COG3102	Protein conserved in bacteria
LGL88_09650	COG0728	peptidoglycan biosynthetic process
LGL88_09655	COG0673	inositol 2-dehydrogenase activity
LGL88_09665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL88_09685	COG3381	protein complex oligomerization
LGL88_09695	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL88_09720	COG3706	GGDEF domain
LGL88_09725	COG0659	secondary active sulfate transmembrane transporter activity
LGL88_09730	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LGL88_09745	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL88_09750	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGL88_09755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGL88_09760	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGL88_09770	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGL88_09780	COG0193	aminoacyl-tRNA hydrolase activity
LGL88_09790	COG0012	GTP binding
LGL88_09810	COG0309	Hydrogenase expression formation protein (HypE)
LGL88_09815	COG0409	Hydrogenase expression formation protein
LGL88_09820	COG0298	carbon dioxide binding
LGL88_09825	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LGL88_09830	COG0375	protein maturation
LGL88_09840	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL88_09845	COG0651	ATP synthesis coupled electron transport
LGL88_09850	COG0650	Formate hydrogenlyase subunit 4
LGL88_09855	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LGL88_09855	COG3261	NADH dehydrogenase
LGL88_09860	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL88_09865	COG3260	NADH ubiquinone oxidoreductase 20
LGL88_09875	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGL88_09880	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL88_09885	COG3383	formate dehydrogenase (NAD+) activity
LGL88_09890	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LGL88_09895	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL88_09915	COG0402	S-adenosylhomocysteine deaminase activity
LGL88_09925	COG1228	amidohydrolase
LGL88_09945	COG3724	N-succinylarginine dihydrolase activity
LGL88_09955	COG3138	arginine N-succinyltransferase
LGL88_09960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGL88_09965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL88_09970	COG1271	oxidase subunit
LGL88_09975	COG1294	oxidase, subunit
LGL88_09985	COG3850	Histidine kinase
LGL88_09990	COG2375	cellular response to nickel ion
LGL88_09995	COG0387	Pfam Sodium calcium exchanger
LGL88_10000	COG1702	phosphate starvation-inducible protein PhoH
LGL88_10005	COG4977	sequence-specific DNA binding
LGL88_10050	COG0471	metal ion transport
LGL88_10055	COG3290	protein histidine kinase activity
LGL88_10060	COG4565	transcriptional regulatory protein
LGL88_10065	COG3493	citrate carrier protein
LGL88_10070	COG0840	transmembrane signaling receptor activity
LGL88_10075	COG0339	signal peptide processing
LGL88_10085	COG2723	6-phospho-beta-galactosidase activity
LGL88_10090	COG3916	Acyl-homoserine-lactone synthase
LGL88_10095	COG2771	luxR family
LGL88_10100	COG0538	isocitrate dehydrogenase activity
LGL88_10105	COG1187	pseudouridine synthase activity
LGL88_10115	COG0482	sulfurtransferase activity
LGL88_10120	COG2915	High frequency lysogenization protein hflD homolog
LGL88_10125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGL88_10135	COG0745	RESPONSE REGULATOR receiver
LGL88_10140	COG2205	protein histidine kinase activity
LGL88_10145	COG2850	peptidyl-arginine hydroxylation
LGL88_10165	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL88_10175	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL88_10180	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGL88_10185	COG3134	Outer membrane lipoprotein
LGL88_10190	COG1252	NADH dehydrogenase
LGL88_10195	COG3150	esterase
LGL88_10210	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LGL88_10215	COG5633	Lipoprotein
LGL88_10220	COG0537	adenosine 5'-monophosphoramidase activity
LGL88_10225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL88_10225	COG1263	PTS System
LGL88_10230	COG0084	hydrolase, TatD family'
LGL88_10235	COG0470	DNA polymerase III
LGL88_10240	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGL88_10245	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGL88_10250	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGL88_10255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL88_10260	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL88_10270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGL88_10275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGL88_10285	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGL88_10290	COG1399	metal-binding, possibly nucleic acid-binding protein
LGL88_10295	COG0424	maF-like protein
LGL88_10300	COG0564	pseudouridine synthase activity
LGL88_10305	COG1530	ribonuclease E activity
LGL88_10315	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LGL88_10320	COG0418	dihydroorotase activity
LGL88_10345	COG0628	permease
LGL88_10355	COG1560	Kdo2-lipid A biosynthetic process
LGL88_10370	COG0346	lactoylglutathione lyase activity
LGL88_10375	COG2943	transferase activity, transferring hexosyl groups
LGL88_10380	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LGL88_10400	COG0288	reversible hydration of carbon dioxide
LGL88_10410	COG2920	part of a sulfur-relay system
LGL88_10415	COG1254	Belongs to the acylphosphatase family
LGL88_10420	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL88_10425	COG3785	DNA binding
LGL88_10430	COG1832	CoA-binding protein
LGL88_10440	COG1803	Methylglyoxal synthase
LGL88_10445	COG0210	DNA helicase
LGL88_10450	COG3304	Inner membrane component domain
LGL88_10455	COG1289	transmembrane transporter activity
LGL88_10460	COG3070	regulator of competence-specific genes
LGL88_10465	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LGL88_10475	COG3120	sequence-specific DNA binding
LGL88_10480	COG1067	ATP-dependent peptidase activity
LGL88_10485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGL88_10490	COG3130	regulation of translation
LGL88_10495	COG3009	Protein conserved in bacteria
LGL88_10500	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL88_10500	COG3008	intermembrane lipid transfer
LGL88_10505	COG2995	paraquat-inducible protein a
LGL88_10510	COG0488	(ABC) transporter
LGL88_10515	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL88_10515	COG0116	Belongs to the methyltransferase superfamily
LGL88_10520	COG3217	Mosc domain protein beta barrel domain protein
LGL88_10520	COG0633	Ferredoxin
LGL88_10530	COG0167	dihydroorotate dehydrogenase activity
LGL88_10535	COG0308	aminopeptidase N
LGL88_10540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGL88_10555	COG1448	Aminotransferase
LGL88_10560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGL88_10565	COG3108	Peptidase M15
LGL88_10570	COG2989	Protein conserved in bacteria
LGL88_10575	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LGL88_10585	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LGL88_10590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL88_10595	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LGL88_10600	COG3173	Aminoglycoside phosphotransferase
LGL88_10605	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LGL88_10610	COG2835	tetraacyldisaccharide 4'-kinase activity
LGL88_10615	COG1278	Cold shock
LGL88_10625	COG5383	Protein conserved in bacteria
LGL88_10630	COG1663	tetraacyldisaccharide 4'-kinase activity
LGL88_10640	COG2333	competence protein COMEC
LGL88_10640	COG0658	competence protein
LGL88_10650	COG0539	negative regulation of cytoplasmic translation
LGL88_10660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGL88_10670	COG0252	asparaginase activity
LGL88_10675	COG1944	ATP diphosphatase activity
LGL88_10680	COG2116	formate transmembrane transporter activity
LGL88_10685	COG1882	Formate acetyltransferase
LGL88_10690	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGL88_10695	COG2814	Major facilitator Superfamily
LGL88_10700	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGL88_10705	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGL88_10710	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGL88_10715	COG3107	peptidoglycan biosynthetic process
LGL88_10715	COG1674	ftsk spoiiie
LGL88_10720	COG1522	sequence-specific DNA binding
LGL88_10725	COG0492	ferredoxin-NADP+ reductase activity
LGL88_10735	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGL88_10745	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGL88_10750	COG0542	response to heat
LGL88_10755	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGL88_10760	COG1278	Cold shock
LGL88_10770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL88_10775	COG2990	Protein conserved in bacteria
LGL88_10780	COG3593	DNA synthesis involved in DNA repair
LGL88_10785	COG2431	L-lysine efflux transmembrane transporter activity
LGL88_10790	COG1151	hydroxylamine reductase activity
LGL88_10795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL88_10800	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LGL88_10805	COG0702	epimerase
LGL88_10810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL88_10815	COG0393	Putative heavy-metal-binding
LGL88_10825	COG1126	abc transporter atp-binding protein
LGL88_10830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL88_10835	COG4215	(ABC) transporter
LGL88_10840	COG4160	amino acid transport
LGL88_10845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL88_10860	COG1177	transmembrane transport
LGL88_10865	COG1176	ABC-type spermidine putrescine transport system, permease component I
LGL88_10870	COG3842	ATPase activity
LGL88_10875	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGL88_10895	COG2985	domain, Protein
LGL88_10895	COG0569	domain protein
LGL88_10905	COG0671	phosphoesterase, PA-phosphatase related
LGL88_10915	COG1349	DNA-binding transcription factor activity
LGL88_10920	COG0814	amino acid
LGL88_10925	COG1760	l-serine dehydratase
LGL88_10930	COG1686	Belongs to the peptidase S11 family
LGL88_10940	COG0626	cystathionine gamma-synthase activity
LGL88_10955	COG0625	glutathione transferase activity
LGL88_10960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL88_10975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGL88_10980	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGL88_10985	COG0131	Imidazoleglycerol-phosphate dehydratase
LGL88_10985	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL88_10995	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGL88_11005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGL88_11005	COG0140	phosphoribosyl-ATP diphosphatase activity
LGL88_11015	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGL88_11020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL88_11025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL88_11030	COG1253	flavin adenine dinucleotide binding
LGL88_11035	COG3069	C4-dicarboxylate transmembrane transporter activity
LGL88_11040	COG2982	Protein involved in outer membrane biogenesis
LGL88_11045	COG0717	Belongs to the dCTP deaminase family
LGL88_11050	COG0572	uridine kinase
LGL88_11055	COG0489	protein tyrosine kinase activity
LGL88_11060	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL88_11060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL88_11070	COG1380	Effector of murein hydrolase LrgA
LGL88_11075	COG1346	cytolysis
LGL88_11085	COG0583	DNA-binding transcription factor activity
LGL88_11095	COG0281	malic enzyme
LGL88_11100	COG2949	membrane
LGL88_11125	COG2311	Membrane
LGL88_11130	COG0302	gtp cyclohydrolase
LGL88_11135	COG0477	Major facilitator Superfamily
LGL88_11140	COG0583	DNA-binding transcription factor activity
LGL88_11160	COG0303	'Molybdopterin
LGL88_11165	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL88_11170	COG0488	(ABC) transporter
LGL88_11175	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL88_11180	COG2239	Acts as a magnesium transporter
LGL88_11185	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGL88_11205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL88_11210	COG0765	amino acid transport
LGL88_11215	COG1126	abc transporter atp-binding protein
LGL88_11220	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LGL88_11225	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGL88_11240	COG0697	spore germination
LGL88_11250	COG1982	Orn Lys Arg decarboxylase major
LGL88_11255	COG0531	amino acid
LGL88_11260	COG1174	glycine betaine transport
LGL88_11265	COG1125	glycine betaine transport
LGL88_11270	COG1174	glycine betaine transport
LGL88_11275	COG1732	Glycine betaine
LGL88_11280	COG2897	thiosulfate sulfurtransferase activity
LGL88_11285	COG4807	Protein conserved in bacteria
LGL88_11290	COG3639	organic phosphonate transmembrane transporter activity
LGL88_11300	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LGL88_11310	COG2261	transglycosylase associated protein
LGL88_11330	COG0277	FAD linked oxidase domain protein
LGL88_11335	COG1686	Belongs to the peptidase S11 family
LGL88_11345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL88_11350	COG0513	Belongs to the DEAD box helicase family
LGL88_11355	COG1309	transcriptional regulator
LGL88_11360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL88_11365	COG1131	(ABC) transporter
LGL88_11370	COG0842	Transport permease protein
LGL88_11375	COG0842	Transport permease protein
LGL88_11380	COG0670	Belongs to the BI1 family
LGL88_11385	COG0314	molybdopterin synthase activity
LGL88_11390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGL88_11400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGL88_11405	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGL88_11410	COG1120	ATPase activity
LGL88_11415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL88_11430	COG4628	conserved protein (DUF2132)
LGL88_11435	COG0556	nucleotide-excision repair
LGL88_11450	COG2226	methyltransferase
LGL88_11455	COG0156	8-amino-7-oxononanoate synthase activity
LGL88_11470	COG2706	6-phosphogluconolactonase activity
LGL88_11475	COG0561	phosphatase activity
LGL88_11485	COG4149	molybdate abc transporter
LGL88_11490	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGL88_11500	COG3585	molybdate ion transport
LGL88_11500	COG2005	Transcriptional regulator
LGL88_11515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGL88_11520	COG1085	galactose-1-phosphate uridylyltransferase
LGL88_11530	COG2017	converts alpha-aldose to the beta-anomer
LGL88_11540	COG0588	phosphoglycerate mutase activity
LGL88_11545	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL88_11555	COG2205	protein histidine kinase activity
LGL88_11555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL88_11565	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGL88_11595	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LGL88_11600	COG2885	chlorophyll binding
LGL88_11605	COG0823	Involved in the tonB-independent uptake of proteins
LGL88_11610	COG3064	Membrane
LGL88_11610	COG3064	Membrane
LGL88_11615	COG0848	biopolymer transport protein
LGL88_11620	COG0811	peptide transport
LGL88_11625	COG0824	Thioesterase
LGL88_11630	COG3790	cyd operon protein YbgE
LGL88_11635	COG4890	Cyd operon protein YbgT
LGL88_11640	COG1294	oxidase, subunit
LGL88_11645	COG1271	oxidase subunit
LGL88_11650	COG0737	Belongs to the 5'-nucleotidase family
LGL88_11655	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGL88_11660	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL88_11665	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL88_11670	COG0567	Dehydrogenase, E1 component
LGL88_11675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL88_11680	COG1053	succinate dehydrogenase
LGL88_11685	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGL88_11720	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGL88_11725	COG1984	allophanate hydrolase subunit 2
LGL88_11730	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGL88_11735	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGL88_11740	COG5212	phosphodiesterase
LGL88_11745	COG0415	Belongs to the DNA photolyase family
LGL88_11750	COG3272	Protein of unknown function (DUF1722)
LGL88_11770	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGL88_11775	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LGL88_11780	COG2205	protein histidine kinase activity
LGL88_11785	COG0745	RESPONSE REGULATOR receiver
LGL88_11795	COG0033	Phosphoglucomutase
LGL88_11800	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LGL88_11805	COG0596	Alpha beta hydrolase
LGL88_11815	COG0840	transmembrane signaling receptor activity
LGL88_11825	COG0735	belongs to the Fur family
LGL88_11850	COG2190	(PTS) system
LGL88_11850	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL88_11850	COG1263	PTS System
LGL88_11860	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL88_11865	COG1940	carbohydrate kinase activity
LGL88_11865	COG1846	Transcriptional regulator
LGL88_11870	COG0647	UMP catabolic process
LGL88_11875	COG0367	asparagine synthase
LGL88_11910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL88_11915	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGL88_11920	COG1702	phosphate starvation-inducible protein PhoH
LGL88_11925	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGL88_11930	COG4535	Mg2 and Co2 transporter CorC
LGL88_11935	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGL88_11945	COG0765	amino acid transport
LGL88_11950	COG0765	amino acid transport
LGL88_11955	COG1126	abc transporter atp-binding protein
LGL88_11960	COG2888	peptidyl-tyrosine sulfation
LGL88_11970	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LGL88_11975	COG1466	dna polymerase III delta subunit
LGL88_11980	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGL88_11990	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL88_12135	COG3772	lysozyme
LGL88_12205	COG1396	sequence-specific DNA binding
LGL88_12240	COG0629	single-stranded DNA binding
LGL88_12305	COG0582	viral genome integration into host DNA
LGL88_12310	COG0799	negative regulation of ribosome biogenesis
LGL88_12315	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGL88_12320	COG0768	penicillin binding
LGL88_12325	COG0772	Belongs to the SEDS family
LGL88_12330	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL88_12335	COG1686	Belongs to the peptidase S11 family
LGL88_12340	COG2921	Belongs to the UPF0250 family
LGL88_12350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGL88_12360	COG3706	GGDEF domain
LGL88_12380	COG1278	Cold shock
LGL88_12385	COG2197	response regulator
LGL88_12415	COG1309	transcriptional regulator
LGL88_12430	COG3250	beta-galactosidase activity
LGL88_12450	COG1215	transferase activity, transferring glycosyl groups
LGL88_12460	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGL88_12490	COG3038	cytochrome b561
LGL88_12515	COG1022	Amp-dependent synthetase and ligase
LGL88_12525	COG1393	Belongs to the ArsC family
LGL88_12530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGL88_12545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGL88_12550	COG2501	S4 domain
LGL88_12580	COG3121	Chaperone
LGL88_12585	COG3188	usher protein
LGL88_12610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL88_12615	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL88_12620	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGL88_12625	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGL88_12630	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGL88_12635	COG4181	ATPase activity
LGL88_12640	COG2755	lipolytic protein G-D-S-L family
LGL88_12645	COG0300	oxidoreductase activity
LGL88_12650	COG3118	belongs to the thioredoxin family
LGL88_12655	COG0330	HflC and HflK could
LGL88_12660	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGL88_12665	COG0789	Transcriptional regulator
LGL88_12670	COG2217	Heavy metal translocating P-type atpase
LGL88_12675	COG3735	TraB family
LGL88_12680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGL88_12690	COG1086	Polysaccharide biosynthesis protein
LGL88_12720	COG0500	methyltransferase
LGL88_12735	COG0737	Belongs to the 5'-nucleotidase family
LGL88_12740	COG4651	solute:proton antiporter activity
LGL88_12740	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL88_12745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL88_12750	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL88_12760	COG0438	transferase activity, transferring glycosyl groups
LGL88_12805	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LGL88_12815	COG0326	Molecular chaperone. Has ATPase activity
LGL88_12820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGL88_12860	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGL88_12865	COG2832	Protein of unknown function (DUF454)
LGL88_12880	COG3264	Mechanosensitive ion channel
LGL88_12880	COG1196	nuclear chromosome segregation
LGL88_12885	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGL88_12890	COG1309	transcriptional regulator
LGL88_12895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL88_12900	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL88_12905	COG0254	rRNA binding
LGL88_12910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL88_12935	COG3695	enzyme binding
LGL88_12940	COG1946	Acyl-CoA thioesterase
LGL88_12945	COG0004	ammonium transporteR
LGL88_12950	COG0347	Belongs to the P(II) protein family
LGL88_12955	COG1132	(ABC) transporter
LGL88_12960	COG1132	(ABC) transporter
LGL88_12965	COG1522	sequence-specific DNA binding
LGL88_12980	COG4533	DNA binding
LGL88_12985	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGL88_12990	COG0824	Thioesterase
LGL88_12995	COG1555	photosystem II stabilization
LGL88_13000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL88_13005	COG0776	regulation of translation
LGL88_13010	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL88_13015	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGL88_13020	COG0740	serine-type endopeptidase activity
LGL88_13030	COG0271	Belongs to the BolA IbaG family
LGL88_13035	COG3056	Lipoprotein
LGL88_13040	COG2223	nitrite transmembrane transporter activity
LGL88_13050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGL88_13055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGL88_13060	COG1845	cytochrome c oxidase, subunit III
LGL88_13065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGL88_13075	COG2814	Major facilitator Superfamily
LGL88_13080	COG1666	GTP binding
LGL88_13085	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGL88_13090	COG0693	protein deglycase activity
LGL88_13125	COG0142	geranyltranstransferase activity
LGL88_13130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGL88_13135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGL88_13140	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGL88_13150	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGL88_13155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL88_13155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL88_13160	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGL88_13165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL88_13170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL88_13175	COG1862	Preprotein translocase
LGL88_13190	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LGL88_13195	COG0450	alkyl hydroperoxide reductase
LGL88_13200	COG0300	oxidoreductase activity
LGL88_13205	COG0366	Alpha amylase catalytic
LGL88_13210	COG1113	amino acid transport
LGL88_13225	COG5002	protein histidine kinase activity
LGL88_13230	COG0745	RESPONSE REGULATOR receiver
LGL88_13235	COG0420	3'-5' exonuclease activity
LGL88_13240	COG0419	ATPase involved in DNA repair
LGL88_13245	COG1940	carbohydrate kinase activity
LGL88_13250	COG2974	May be involved in recombination
LGL88_13260	COG4126	flavin adenine dinucleotide binding
LGL88_13280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL88_13315	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGL88_13330	COG1073	alpha beta
LGL88_13335	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LGL88_13340	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGL88_13345	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL88_13355	COG2991	Protein conserved in bacteria
LGL88_13360	COG1477	protein flavinylation
LGL88_13370	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL88_13375	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL88_13380	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL88_13385	COG1805	sodium ion transport
LGL88_13395	COG3034	peptidoglycan biosynthetic process
LGL88_13400	COG0121	glutamine amidotransferase
LGL88_13405	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL88_13410	COG1960	acyl-CoA dehydrogenase activity
LGL88_13420	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL88_13430	COG2226	methyltransferase
LGL88_13440	COG1388	LysM domain
LGL88_13440	COG0741	lytic transglycosylase activity
LGL88_13445	COG3021	interspecies interaction between organisms
LGL88_13480	COG0542	response to heat
LGL88_13485	COG1496	oxidoreductase activity
LGL88_13490	COG0564	pseudouridine synthase activity
LGL88_13495	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL88_13500	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGL88_13510	COG1605	Chorismate mutase
LGL88_13510	COG0077	Prephenate dehydratase
LGL88_13515	COG0287	Prephenate dehydrogenase
LGL88_13515	COG1605	Chorismate mutase
LGL88_13520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL88_13525	COG3279	Response regulator of the LytR AlgR family
LGL88_13530	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL88_13535	COG3137	Salt-induced outer membrane protein
LGL88_13540	COG0335	large ribosomal subunit rRNA binding
LGL88_13545	COG0336	Belongs to the RNA methyltransferase TrmD family
LGL88_13550	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGL88_13560	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGL88_13565	COG4137	Cytochrome C assembly protein
LGL88_13570	COG4536	flavin adenine dinucleotide binding
LGL88_13575	COG1854	S-ribosylhomocysteine lyase activity
LGL88_13580	COG2918	glutathione biosynthetic process
LGL88_13585	COG1238	metal cluster binding
LGL88_13590	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL88_13625	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGL88_13630	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGL88_13635	COG2137	regulation of response to DNA damage stimulus
LGL88_13640	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGL88_13655	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL88_13655	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL88_13680	COG3031	protein transport across the cell outer membrane
LGL88_13690	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL88_13735	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGL88_13745	COG3397	chitin binding
LGL88_13765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL88_13895	COG0741	lytic transglycosylase activity
LGL88_13915	COG2205	protein histidine kinase activity
LGL88_13915	COG0784	Response regulator, receiver
LGL88_13925	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGL88_13930	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGL88_13935	COG4942	peptidase
LGL88_13935	COG1388	LysM domain
LGL88_13945	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGL88_13950	COG0585	pseudouridine synthase activity
LGL88_13955	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGL88_13965	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGL88_13975	COG0529	Catalyzes the synthesis of activated sulfate
LGL88_13980	COG2895	sulfate adenylyltransferase (ATP) activity
LGL88_13985	COG0175	sulfate reduction
LGL88_13990	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGL88_13990	COG1648	precorrin-2 dehydrogenase activity
LGL88_13995	COG2234	aminopeptidase activity
LGL88_14010	COG0175	sulfate reduction
LGL88_14020	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGL88_14025	COG0720	synthase
LGL88_14030	COG0602	queuosine metabolic process
LGL88_14040	COG0504	CTP synthase activity
LGL88_14045	COG3956	TIGRFAM MazG family protein
LGL88_14050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL88_14055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL88_14065	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL88_14070	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL88_14075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL88_14085	COG2860	membrane
LGL88_14090	COG0316	Belongs to the HesB IscA family
LGL88_14100	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGL88_14105	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL88_14110	COG1643	Atp-dependent helicase
LGL88_14115	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGL88_14120	COG1489	DNA binding
LGL88_14135	COG0617	tRNA 3'-terminal CCA addition
LGL88_14140	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGL88_14145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGL88_14150	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGL88_14155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGL88_14160	COG0726	polysaccharide deacetylase
LGL88_14165	COG0842	Transport permease protein
LGL88_14170	COG1131	(ABC) transporter
LGL88_14175	COG0288	reversible hydration of carbon dioxide
LGL88_14185	COG2132	Multicopper oxidase
LGL88_14195	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGL88_14210	COG3112	Uncharacterised protein family (UPF0231)
LGL88_14215	COG1049	propionate catabolic process, 2-methylcitrate cycle
LGL88_14225	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL88_14230	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL88_14235	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LGL88_14240	COG2186	Transcriptional regulator
LGL88_14245	COG1113	amino acid transport
LGL88_14255	COG3725	Membrane protein required for beta-lactamase induction
LGL88_14270	COG4969	Belongs to the N-Me-Phe pilin family
LGL88_14275	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL88_14280	COG1459	type II secretion system
LGL88_14285	COG0516	GMP reductase activity
LGL88_14305	COG0494	nUDIX hydrolase
LGL88_14330	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGL88_14335	COG0849	cell division
LGL88_14340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LGL88_14350	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL88_14355	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGL88_14360	COG0772	Belongs to the SEDS family
LGL88_14375	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGL88_14380	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGL88_14385	COG0768	penicillin binding
LGL88_14390	COG3116	cell division
LGL88_14395	COG0275	rRNA processing
LGL88_14410	COG0675	Transposase, IS605 OrfB family
LGL88_14430	COG0028	Belongs to the TPP enzyme family
LGL88_14435	COG1022	Amp-dependent synthetase and ligase
LGL88_14450	COG0473	3-isopropylmalate dehydrogenase activity
LGL88_14455	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL88_14465	COG2814	Major facilitator Superfamily
LGL88_14480	COG4143	(ABC) transporter
LGL88_14485	COG1178	ABC-type Fe3 transport system permease component
LGL88_14495	COG0586	Pfam SNARE associated Golgi protein
LGL88_14500	COG0417	DNA replication proofreading
LGL88_14505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGL88_14510	COG0564	pseudouridine synthase activity
LGL88_14520	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LGL88_14530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LGL88_14535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGL88_14540	COG2967	ApaG domain
LGL88_14565	COG2966	Psort location CytoplasmicMembrane, score
LGL88_14575	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGL88_14590	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGL88_14595	COG1047	Peptidyl-prolyl cis-trans
LGL88_14600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGL88_14610	COG0196	riboflavin kinase activity
LGL88_14620	COG0583	DNA-binding transcription factor activity
LGL88_14625	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL88_14635	COG0443	Heat shock 70 kDa protein
LGL88_14640	COG1584	GPR1 FUN34 yaaH family protein
LGL88_14650	COG0477	Major facilitator Superfamily
LGL88_14655	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGL88_14660	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL88_14695	COG0745	RESPONSE REGULATOR receiver
LGL88_14700	COG3045	CreA protein
LGL88_14705	COG2207	Transcriptional regulator
LGL88_14705	COG3708	Transcriptional regulator
LGL88_14710	COG0406	alpha-ribazole phosphatase activity
LGL88_14715	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGL88_14720	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LGL88_14725	COG0741	lytic transglycosylase activity
LGL88_14745	COG0488	(ABC) transporter
LGL88_14760	COG0560	Phosphoserine phosphatase
LGL88_14765	COG3726	membrane protein affecting hemolysin expression
LGL88_14775	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGL88_14790	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL88_14795	COG0084	hydrolase, TatD family'
LGL88_14800	COG4667	esterase of the alpha-beta hydrolase superfamily
LGL88_14810	COG2823	Periplasmic or secreted lipoprotein
LGL88_14825	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LGL88_14865	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LGL88_14865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL88_14865	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL88_14870	COG1461	Dihydroxyacetone kinase
LGL88_14875	COG2376	Dihydroxyacetone kinase
LGL88_14885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL88_14890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL88_14905	COG0859	PFAM glycosyl transferase family 9
LGL88_14930	COG3119	arylsulfatase activity
LGL88_14935	COG0641	radical SAM
LGL88_14945	COG1028	Short-chain dehydrogenase reductase Sdr
LGL88_14955	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL88_14965	COG3716	PTS system mannose fructose sorbose family IID component
LGL88_14970	COG3715	PTS system
LGL88_14975	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL88_14980	COG2222	sugar isomerase
LGL88_14990	COG1349	DNA-binding transcription factor activity
LGL88_14995	COG3119	arylsulfatase activity
LGL88_15015	COG5492	domain, Protein
LGL88_15105	COG3077	Addiction module antitoxin, RelB DinJ family
LGL88_15145	COG0582	viral genome integration into host DNA
LGL88_15155	COG0795	lipopolysaccharide-transporting ATPase activity
LGL88_15160	COG0795	lipopolysaccharide-transporting ATPase activity
LGL88_15165	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGL88_15170	COG2927	DNA polymerase III (CHI subunit)
LGL88_15185	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LGL88_15205	COG3624	Phosphonate C-P lyase system protein PhnG
LGL88_15210	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LGL88_15215	COG3626	phosphonate metabolism
LGL88_15220	COG3627	carbon phosphorus lyase activity
LGL88_15225	COG4107	phosphonate C-P lyase system protein PhnK
LGL88_15230	COG4778	phosphonate C-P lyase system protein PhnL
LGL88_15235	COG3454	Phosphonate metabolism
LGL88_15240	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LGL88_15245	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGL88_15250	COG0702	epimerase
LGL88_15255	COG3787	Belongs to the UPF0306 family
LGL88_15265	COG1982	Orn Lys Arg decarboxylase major
LGL88_15270	COG0531	amino acid
LGL88_15275	COG2827	Endonuclease containing a URI domain
LGL88_15280	COG3153	acetyltransferase
LGL88_15285	COG3154	lipid carrier protein
LGL88_15290	COG0826	peptidase U32
LGL88_15295	COG0826	peptidase U32
LGL88_15305	COG0814	amino acid
LGL88_15310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGL88_15315	COG0513	Belongs to the DEAD box helicase family
LGL88_15330	COG1185	polyribonucleotide nucleotidyltransferase activity
LGL88_15345	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGL88_15355	COG0195	Participates in both transcription termination and antitermination
LGL88_15375	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGL88_15380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGL88_15385	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGL88_15395	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LGL88_15400	COG1534	Rna-binding protein
LGL88_15410	COG2027	D-alanyl-D-alanine carboxypeptidase
LGL88_15415	COG0745	RESPONSE REGULATOR receiver
LGL88_15420	COG0642	Histidine kinase
LGL88_15425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGL88_15430	COG0697	spore germination
LGL88_15445	COG0142	geranyltranstransferase activity
LGL88_15460	COG3423	Transcriptional regulator
LGL88_15475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL88_15485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGL88_15490	COG2105	PFAM AIG2 family protein
LGL88_15495	COG2911	Protein conserved in bacteria
LGL88_15500	COG0729	surface antigen
LGL88_15505	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL88_15510	COG1253	flavin adenine dinucleotide binding
LGL88_15520	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LGL88_15525	COG1218	3'(2'),5'-bisphosphate nucleotidase
LGL88_15530	COG0737	Belongs to the 5'-nucleotidase family
LGL88_15540	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL88_15545	COG3061	Opacity-associated protein A
LGL88_15550	COG0359	binds to the 23S rRNA
LGL88_15555	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGL88_15560	COG2965	DNA replication, synthesis of RNA primer
LGL88_15565	COG0360	Binds together with S18 to 16S ribosomal RNA
LGL88_15575	COG1073	alpha beta
LGL88_15595	COG3188	usher protein
LGL88_15600	COG3121	Chaperone
LGL88_15620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL88_15625	COG0557	exoribonuclease II activity
LGL88_15630	COG1959	2 iron, 2 sulfur cluster binding
LGL88_15635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGL88_15640	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LGL88_15645	COG0330	HflC and HflK could
LGL88_15650	COG0330	HflC and HflK could
LGL88_15655	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGL88_15665	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGL88_15675	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL88_15680	COG0802	atpase or kinase
LGL88_15685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGL88_15685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGL88_15690	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGL88_15710	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGL88_15715	COG1162	GTPase activity
LGL88_15720	COG0688	phosphatidylethanolamine metabolic process
LGL88_15725	COG3264	Mechanosensitive ion channel
LGL88_15725	COG1511	domain protein
LGL88_15730	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGL88_15735	COG1053	succinate dehydrogenase
LGL88_15740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL88_15745	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL88_15750	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL88_15770	COG3188	usher protein
LGL88_15790	COG3397	chitin binding
LGL88_15800	COG1509	lysine 2,3-aminomutase activity
LGL88_15830	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL88_15840	COG4232	protein-disulfide reductase activity
LGL88_15845	COG1309	transcriptional regulator
LGL88_15855	COG1301	dicarboxylic acid transport
LGL88_15860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGL88_15865	COG3162	membrane
LGL88_15870	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL88_15895	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LGL88_15900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGL88_15905	COG1739	Uncharacterized protein family UPF0029
LGL88_15915	COG1024	Enoyl-CoA hydratase
LGL88_15915	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL88_15925	COG0543	2 iron, 2 sulfur cluster binding
LGL88_15940	COG0250	Participates in transcription elongation, termination and antitermination
LGL88_15955	COG0805	protein transport
LGL88_15960	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL88_15965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL88_15970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGL88_15975	COG3165	ubiquinone biosynthetic process from chorismate
LGL88_15980	COG2226	methyltransferase
LGL88_15985	COG1322	Protein conserved in bacteria
LGL88_15990	COG0586	Pfam SNARE associated Golgi protein
LGL88_15995	COG1966	Carbon starvation protein
LGL88_16010	COG0412	Dienelactone hydrolase
LGL88_16015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGL88_16020	COG0583	DNA-binding transcription factor activity
LGL88_16025	COG0697	spore germination
LGL88_16035	COG0584	glycerophosphoryl diester phosphodiesterase
LGL88_16045	COG0395	ABC-type sugar transport system, permease component
LGL88_16050	COG1175	transmembrane transport
LGL88_16055	COG1653	transport
LGL88_16090	COG0410	ABC transporter
LGL88_16100	COG4177	L-phenylalanine transmembrane transporter activity
LGL88_16120	COG1929	Belongs to the glycerate kinase type-1 family
LGL88_16125	COG2610	gluconate transmembrane transporter activity
LGL88_16130	COG3835	regulator
LGL88_16140	COG2177	Part of the ABC transporter FtsEX involved in
LGL88_16145	COG2884	Cell division ATP-binding protein ftsE
LGL88_16150	COG0552	protein localization to endoplasmic reticulum
LGL88_16150	COG0552	protein localization to endoplasmic reticulum
LGL88_16155	COG0742	ribosomal rna small subunit methyltransferase
LGL88_16160	COG3776	membrane
LGL88_16175	COG3714	YhhN family
LGL88_16190	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGL88_16200	COG0247	lactate metabolic process
LGL88_16210	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL88_16220	COG2271	Major facilitator Superfamily
LGL88_16225	COG0584	glycerophosphoryl diester phosphodiesterase
LGL88_16230	COG0561	phosphatase activity
LGL88_16235	COG2267	carboxylic ester hydrolase activity
LGL88_16240	COG1280	lysine exporter protein (LysE YggA)
LGL88_16245	COG0514	ATP-dependent DNA helicase (RecQ)
LGL88_16250	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LGL88_16255	COG2050	protein possibly involved in aromatic compounds catabolism
LGL88_16275	COG5564	TIM-barrel signal transduction protein
LGL88_16280	COG5441	Belongs to the UPF0261 family
LGL88_16290	COG0210	DNA helicase
LGL88_16295	COG1011	Hydrolase
LGL88_16300	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL88_16305	COG3159	Protein conserved in bacteria
LGL88_16310	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGL88_16315	COG5567	small periplasmic lipoprotein
LGL88_16325	COG3072	Adenylate cyclase
LGL88_16330	COG0181	hydroxymethylbilane synthase activity
LGL88_16335	COG1587	Uroporphyrinogen-III synthase
LGL88_16340	COG2959	enzyme of heme biosynthesis
LGL88_16345	COG3071	HemY protein
LGL88_16395	COG2244	polysaccharide biosynthetic process
LGL88_16400	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL88_16405	COG0456	acetyltransferase
LGL88_16410	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGL88_16415	COG1088	dTDP-glucose 4,6-dehydratase activity
LGL88_16420	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGL88_16425	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL88_16430	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL88_16435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGL88_16440	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGL88_16445	COG3118	belongs to the thioredoxin family
LGL88_16455	COG0248	Ppx GppA phosphatase
LGL88_16465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL88_16480	COG3397	chitin binding
LGL88_16490	COG0129	dihydroxy-acid dehydratase activity
LGL88_16500	COG3978	acetolactate synthase activity
LGL88_16520	COG3085	chromosome segregation
LGL88_16525	COG0583	DNA-binding transcription factor activity
LGL88_16605	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL88_16615	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL88_16615	COG0678	peroxiredoxin activity
LGL88_16620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL88_16655	COG1629	transport
LGL88_16660	COG0165	Argininosuccinate lyase
LGL88_16665	COG0137	argininosuccinate synthase activity
LGL88_16670	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL88_16720	COG0460	homoserine dehydrogenase
LGL88_16720	COG0527	aspartate kinase activity
LGL88_16725	COG0626	cystathionine gamma-synthase activity
LGL88_16730	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LGL88_16740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGL88_16745	COG1609	Transcriptional regulator
LGL88_16750	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL88_16755	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGL88_16760	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGL88_16765	COG1575	Belongs to the MenA family. Type 1 subfamily
LGL88_16770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGL88_16775	COG3074	FtsZ-dependent cytokinesis
LGL88_16780	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGL88_16785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGL88_16790	COG1494	fructose-1,6-bisphosphatase
LGL88_16795	COG2814	Major facilitator Superfamily
LGL88_16805	COG3152	Membrane
LGL88_16820	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGL88_16830	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL88_16835	COG3678	ATP-independent chaperone mediated protein folding
LGL88_16840	COG0745	RESPONSE REGULATOR receiver
LGL88_16845	COG2205	protein histidine kinase activity
LGL88_16850	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGL88_16855	COG1045	serine acetyltransferase
LGL88_16860	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGL88_16865	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LGL88_16870	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL88_16875	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGL88_16880	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGL88_16885	COG4942	peptidase
LGL88_16890	COG2861	carbohydrate metabolic process
LGL88_16905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL88_16910	COG0859	PFAM glycosyl transferase family 9
LGL88_16915	COG0859	PFAM glycosyl transferase family 9
LGL88_16920	COG1519	Transferase
LGL88_16940	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGL88_16945	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGL88_16950	COG2003	Belongs to the UPF0758 family
LGL88_16955	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGL88_16960	COG0756	dUTP diphosphatase activity
LGL88_16965	COG1309	transcriptional regulator
LGL88_16970	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGL88_16975	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGL88_16980	COG1561	YicC-like family, N-terminal region
LGL88_17020	COG5001	Diguanylate cyclase
LGL88_17025	COG1024	Enoyl-CoA hydratase
LGL88_17030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL88_17040	COG2860	membrane
LGL88_17045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL88_17055	COG1758	RNA polymerase activity
LGL88_17060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL88_17065	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL88_17070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGL88_17075	COG0786	glutamate:sodium symporter activity
LGL88_17080	COG2233	PERMEase
LGL88_17085	COG2982	Protein involved in outer membrane biogenesis
LGL88_17090	COG0456	acetyltransferase
LGL88_17105	COG1011	Hydrolase
LGL88_17120	COG3852	Histidine kinase
LGL88_17130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL88_17140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGL88_17145	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL88_17145	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL88_17150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL88_17155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGL88_17160	COG3084	Protein conserved in bacteria
LGL88_17170	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGL88_17195	COG2186	Transcriptional regulator
LGL88_17200	COG1609	Transcriptional regulator
LGL88_17205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL88_17215	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL88_17220	COG1129	ABC transporter
LGL88_17225	COG1869	D-ribose catabolic process
LGL88_17230	COG3158	transport of potassium into the cell
LGL88_17235	COG0714	Associated with various cellular activities
LGL88_17240	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LGL88_17250	COG2502	aspartate--ammonia ligase
LGL88_17255	COG1522	sequence-specific DNA binding
LGL88_17260	COG0716	FMN binding
LGL88_17265	COG0445	tRNA wobble uridine modification
LGL88_17270	COG0357	Ribosomal RNA small subunit methyltransferase G
LGL88_17275	COG3312	ion transport
LGL88_17280	COG0356	it plays a direct role in the translocation of protons across the membrane
LGL88_17290	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGL88_17300	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGL88_17305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGL88_17315	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGL88_17330	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGL88_17335	COG0573	inorganic phosphate transmembrane transporter activity
LGL88_17340	COG0581	inorganic phosphate transmembrane transporter activity
LGL88_17350	COG0704	Plays a role in the regulation of phosphate uptake
LGL88_17355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL88_17360	COG0765	amino acid transport
LGL88_17365	COG0765	amino acid transport
LGL88_17370	COG2252	PERMEase
LGL88_17375	COG0840	transmembrane signaling receptor activity
LGL88_17385	COG3121	Chaperone
LGL88_17400	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGL88_17405	COG0706	membrane insertase activity
LGL88_17415	COG0594	ribonuclease P activity
LGL88_17420	COG0230	Belongs to the bacterial ribosomal protein bL34 family