locus-tag	class	description
LGL85_00010	COG0592	DNA-directed DNA polymerase activity
LGL85_00020	COG0187	DNA topoisomerase II activity
LGL85_00025	COG0561	phosphatase activity
LGL85_00030	COG0823	Involved in the tonB-independent uptake of proteins
LGL85_00035	COG5645	(Lipo)protein
LGL85_00050	COG0569	domain protein
LGL85_00050	COG2985	domain, Protein
LGL85_00055	COG3977	Valine--pyruvate aminotransferase
LGL85_00060	COG2885	chlorophyll binding
LGL85_00085	COG2818	Glycosylase
LGL85_00135	COG2213	PTS system mannitol-specific
LGL85_00135	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL85_00145	COG3722	fumarate hydratase activity
LGL85_00155	COG2258	MOSC domain
LGL85_00160	COG0840	transmembrane signaling receptor activity
LGL85_00165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL85_00180	COG0437	4 iron, 4 sulfur cluster binding
LGL85_00185	COG2864	formate dehydrogenase
LGL85_00195	COG1921	L-seryl-tRNASec selenium transferase activity
LGL85_00200	COG3276	selenocysteine insertion sequence binding
LGL85_00205	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LGL85_00215	COG3274	enterobacterial common antigen metabolic process
LGL85_00225	COG0582	viral genome integration into host DNA
LGL85_00270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGL85_00275	COG2986	histidine ammonia-lyase
LGL85_00295	COG2194	sulfuric ester hydrolase activity
LGL85_00300	COG2197	response regulator
LGL85_00305	COG3851	Histidine kinase
LGL85_00310	COG2271	Major facilitator Superfamily
LGL85_00320	COG0747	negative chemotaxis
LGL85_00325	COG0601	transmembrane transport
LGL85_00330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL85_00335	COG0444	Belongs to the ABC transporter superfamily
LGL85_00340	COG4608	Belongs to the ABC transporter superfamily
LGL85_00345	COG2194	sulfuric ester hydrolase activity
LGL85_00370	COG1215	transferase activity, transferring glycosyl groups
LGL85_00375	COG1215	transferase activity, transferring glycosyl groups
LGL85_00380	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGL85_00385	COG3118	belongs to the thioredoxin family
LGL85_00385	COG0457	Tetratricopeptide repeat
LGL85_00390	COG2199	diguanylate cyclase activity
LGL85_00390	COG2200	EAL domain
LGL85_00395	COG1301	dicarboxylic acid transport
LGL85_00400	COG0612	Peptidase, M16
LGL85_00405	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL85_00410	COG1942	4-Oxalocrotonate Tautomerase
LGL85_00415	COG2200	EAL domain
LGL85_00420	COG2134	cdp-diacylglycerol pyrophosphatase
LGL85_00425	COG1295	ribonuclease BN
LGL85_00435	COG1301	dicarboxylic acid transport
LGL85_00440	COG0626	cystathionine gamma-synthase activity
LGL85_00460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL85_00465	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGL85_00470	COG0339	signal peptide processing
LGL85_00475	COG0742	ribosomal rna small subunit methyltransferase
LGL85_00485	COG0589	response to stress
LGL85_00495	COG0306	phosphate transporter
LGL85_00500	COG2081	HI0933 family
LGL85_00510	COG1247	-acetyltransferase
LGL85_00520	COG1741	Belongs to the pirin family
LGL85_00525	COG1609	Transcriptional regulator
LGL85_00535	COG3265	gluconokinase activity
LGL85_00540	COG2095	MarC family integral membrane protein
LGL85_00545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL85_00550	COG3275	phosphorelay sensor kinase activity
LGL85_00555	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGL85_00560	COG1523	belongs to the glycosyl hydrolase 13 family
LGL85_00565	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGL85_00570	COG0297	glycogen (starch) synthase activity
LGL85_00575	COG0058	SHG alpha-glucan phosphorylase activity
LGL85_00580	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL85_00585	COG1349	DNA-binding transcription factor activity
LGL85_00590	COG0705	Rhomboid family
LGL85_00600	COG2909	trisaccharide binding
LGL85_00605	COG0058	SHG alpha-glucan phosphorylase activity
LGL85_00610	COG1640	4-alpha-glucanotransferase
LGL85_00620	COG1040	competence protein
LGL85_00625	COG0596	Alpha beta hydrolase
LGL85_00645	COG1918	ferrous iron import across plasma membrane
LGL85_00650	COG2183	response to ionizing radiation
LGL85_00675	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL85_00690	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGL85_00700	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGL85_00705	COG1011	Hydrolase
LGL85_00715	COG0494	nUDIX hydrolase
LGL85_00720	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL85_00745	COG4796	Type ii and iii secretion system protein
LGL85_00750	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL85_00770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGL85_00780	COG0180	Tryptophanyl-tRNA synthetase
LGL85_00800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGL85_00805	COG0402	S-adenosylhomocysteine deaminase activity
LGL85_00810	COG0738	Major facilitator superfamily
LGL85_00825	COG1609	Transcriptional regulator
LGL85_00830	COG1486	melibiose metabolic process
LGL85_00835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL85_00850	COG1289	transmembrane transporter activity
LGL85_00855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL85_00860	COG1765	OsmC-like protein
LGL85_00885	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL85_00890	COG3954	Phosphoribulokinase
LGL85_00900	COG0429	hydrolase of the alpha beta-hydrolase fold
LGL85_00910	COG0859	PFAM glycosyl transferase family 9
LGL85_00915	COG1216	Glycosyl transferase, family 2
LGL85_00920	COG0488	(ABC) transporter
LGL85_00925	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL85_00935	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGL85_00940	COG1047	Peptidyl-prolyl cis-trans
LGL85_00950	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL85_00955	COG2964	Protein conserved in bacteria
LGL85_00965	COG2923	Belongs to the DsrF TusC family
LGL85_00970	COG2168	tRNA wobble position uridine thiolation
LGL85_00975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGL85_00980	COG0049	tRNA binding
LGL85_00990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGL85_01005	COG0051	transcription antitermination factor activity, RNA binding
LGL85_01010	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGL85_01020	COG0089	rRNA binding
LGL85_01025	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGL85_01030	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGL85_01035	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGL85_01045	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGL85_01050	COG0255	Belongs to the universal ribosomal protein uL29 family
LGL85_01055	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGL85_01060	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGL85_01070	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGL85_01095	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGL85_01100	COG1841	ribosomal large subunit assembly
LGL85_01105	COG0200	Binds to the 23S rRNA
LGL85_01110	COG0201	protein transport
LGL85_01115	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL85_01120	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGL85_01130	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGL85_01140	COG0203	ribosomal protein L17
LGL85_01145	COG0789	Transcriptional regulator
LGL85_01150	COG3036	rescue of stalled ribosome
LGL85_01155	COG1970	mechanosensitive ion channel activity
LGL85_01165	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGL85_01165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGL85_01170	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGL85_01175	COG0242	peptide deformylase activity
LGL85_01180	COG0758	DNA mediated transformation
LGL85_01185	COG2922	Belongs to the Smg family
LGL85_01190	COG0551	DNA topoisomerase type I activity
LGL85_01195	COG0009	L-threonylcarbamoyladenylate synthase
LGL85_01205	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGL85_01230	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL85_01235	COG3162	membrane
LGL85_01240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGL85_01245	COG1301	dicarboxylic acid transport
LGL85_01255	COG2391	methyltransferase activity
LGL85_01260	COG0425	Belongs to the sulfur carrier protein TusA family
LGL85_01265	COG1086	Polysaccharide biosynthesis protein
LGL85_01270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL85_01275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL85_01280	COG2089	acid synthase
LGL85_01300	COG1083	cytidylyl-transferase
LGL85_01300	COG2755	lipolytic protein G-D-S-L family
LGL85_01305	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_01325	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL85_01325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL85_01330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LGL85_01350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL85_01370	COG1309	transcriptional regulator
LGL85_01380	COG4232	protein-disulfide reductase activity
LGL85_01390	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL85_01420	COG1509	lysine 2,3-aminomutase activity
LGL85_01430	COG3397	chitin binding
LGL85_01450	COG3188	usher protein
LGL85_01470	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL85_01475	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL85_01480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL85_01485	COG1053	succinate dehydrogenase
LGL85_01490	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGL85_01495	COG3264	Mechanosensitive ion channel
LGL85_01495	COG1511	domain protein
LGL85_01500	COG0688	phosphatidylethanolamine metabolic process
LGL85_01505	COG1162	GTPase activity
LGL85_01510	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGL85_01530	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGL85_01535	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGL85_01535	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGL85_01540	COG0802	atpase or kinase
LGL85_01545	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL85_01555	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGL85_01565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGL85_01570	COG0330	HflC and HflK could
LGL85_01575	COG0330	HflC and HflK could
LGL85_01580	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LGL85_01585	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGL85_01590	COG1959	2 iron, 2 sulfur cluster binding
LGL85_01595	COG0557	exoribonuclease II activity
LGL85_01600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL85_01620	COG3121	Chaperone
LGL85_01625	COG3188	usher protein
LGL85_01645	COG1073	alpha beta
LGL85_01655	COG0360	Binds together with S18 to 16S ribosomal RNA
LGL85_01660	COG2965	DNA replication, synthesis of RNA primer
LGL85_01665	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGL85_01670	COG0359	binds to the 23S rRNA
LGL85_01675	COG3061	Opacity-associated protein A
LGL85_01680	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL85_01690	COG0737	Belongs to the 5'-nucleotidase family
LGL85_01695	COG1218	3'(2'),5'-bisphosphate nucleotidase
LGL85_01700	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LGL85_01710	COG1253	flavin adenine dinucleotide binding
LGL85_01715	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL85_01720	COG0729	surface antigen
LGL85_01725	COG2911	Protein conserved in bacteria
LGL85_01730	COG2105	PFAM AIG2 family protein
LGL85_01735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGL85_01745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL85_01760	COG3423	Transcriptional regulator
LGL85_01775	COG0142	geranyltranstransferase activity
LGL85_01795	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGL85_01800	COG0642	Histidine kinase
LGL85_01805	COG0745	RESPONSE REGULATOR receiver
LGL85_01810	COG2027	D-alanyl-D-alanine carboxypeptidase
LGL85_01820	COG1534	Rna-binding protein
LGL85_01825	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LGL85_01835	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGL85_01840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGL85_01845	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGL85_01865	COG0195	Participates in both transcription termination and antitermination
LGL85_01875	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGL85_01890	COG1185	polyribonucleotide nucleotidyltransferase activity
LGL85_01905	COG0513	Belongs to the DEAD box helicase family
LGL85_01910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGL85_01925	COG0826	peptidase U32
LGL85_01930	COG0826	peptidase U32
LGL85_01935	COG3154	lipid carrier protein
LGL85_01940	COG3153	acetyltransferase
LGL85_01945	COG2827	Endonuclease containing a URI domain
LGL85_01950	COG0531	amino acid
LGL85_01955	COG1982	Orn Lys Arg decarboxylase major
LGL85_01965	COG3787	Belongs to the UPF0306 family
LGL85_01970	COG0702	epimerase
LGL85_01975	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGL85_01980	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LGL85_01985	COG3454	Phosphonate metabolism
LGL85_01990	COG4778	phosphonate C-P lyase system protein PhnL
LGL85_01995	COG4107	phosphonate C-P lyase system protein PhnK
LGL85_02000	COG3627	carbon phosphorus lyase activity
LGL85_02005	COG3626	phosphonate metabolism
LGL85_02010	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LGL85_02015	COG3624	Phosphonate C-P lyase system protein PhnG
LGL85_02035	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LGL85_02050	COG2927	DNA polymerase III (CHI subunit)
LGL85_02055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGL85_02060	COG0795	lipopolysaccharide-transporting ATPase activity
LGL85_02065	COG0795	lipopolysaccharide-transporting ATPase activity
LGL85_02105	COG5492	domain, Protein
LGL85_02125	COG3119	arylsulfatase activity
LGL85_02130	COG1349	DNA-binding transcription factor activity
LGL85_02140	COG2222	sugar isomerase
LGL85_02145	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_02150	COG3715	PTS system
LGL85_02155	COG3716	PTS system mannose fructose sorbose family IID component
LGL85_02165	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL85_02175	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_02185	COG0641	radical SAM
LGL85_02190	COG3119	arylsulfatase activity
LGL85_02215	COG0859	PFAM glycosyl transferase family 9
LGL85_02230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL85_02235	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL85_02245	COG2376	Dihydroxyacetone kinase
LGL85_02250	COG1461	Dihydroxyacetone kinase
LGL85_02255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL85_02255	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL85_02255	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LGL85_02295	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LGL85_02310	COG2823	Periplasmic or secreted lipoprotein
LGL85_02320	COG4667	esterase of the alpha-beta hydrolase superfamily
LGL85_02325	COG0084	hydrolase, TatD family'
LGL85_02330	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL85_02345	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGL85_02355	COG3726	membrane protein affecting hemolysin expression
LGL85_02360	COG0560	Phosphoserine phosphatase
LGL85_02375	COG0488	(ABC) transporter
LGL85_02400	COG0741	lytic transglycosylase activity
LGL85_02405	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LGL85_02410	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGL85_02415	COG0406	alpha-ribazole phosphatase activity
LGL85_02420	COG2207	Transcriptional regulator
LGL85_02420	COG3708	Transcriptional regulator
LGL85_02425	COG3045	CreA protein
LGL85_02430	COG0745	RESPONSE REGULATOR receiver
LGL85_02465	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL85_02470	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGL85_02475	COG0477	Major facilitator Superfamily
LGL85_02485	COG1584	GPR1 FUN34 yaaH family protein
LGL85_02490	COG0443	Heat shock 70 kDa protein
LGL85_02500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL85_02505	COG0583	DNA-binding transcription factor activity
LGL85_02515	COG0196	riboflavin kinase activity
LGL85_02525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGL85_02530	COG1047	Peptidyl-prolyl cis-trans
LGL85_02535	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGL85_02550	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGL85_02560	COG2966	Psort location CytoplasmicMembrane, score
LGL85_02585	COG2967	ApaG domain
LGL85_02590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGL85_02595	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LGL85_02605	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LGL85_02615	COG0564	pseudouridine synthase activity
LGL85_02620	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGL85_02625	COG0417	DNA replication proofreading
LGL85_02630	COG0586	Pfam SNARE associated Golgi protein
LGL85_02640	COG1178	ABC-type Fe3 transport system permease component
LGL85_02645	COG4143	(ABC) transporter
LGL85_02660	COG2814	Major facilitator Superfamily
LGL85_02670	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL85_02675	COG0473	3-isopropylmalate dehydrogenase activity
LGL85_02690	COG1022	Amp-dependent synthetase and ligase
LGL85_02695	COG0028	Belongs to the TPP enzyme family
LGL85_02720	COG0275	rRNA processing
LGL85_02725	COG3116	cell division
LGL85_02730	COG0768	penicillin binding
LGL85_02735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGL85_02740	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGL85_02755	COG0772	Belongs to the SEDS family
LGL85_02760	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGL85_02765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL85_02780	COG0849	cell division
LGL85_02785	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGL85_02810	COG0494	nUDIX hydrolase
LGL85_02830	COG0516	GMP reductase activity
LGL85_02835	COG1459	type II secretion system
LGL85_02840	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL85_02845	COG4969	Belongs to the N-Me-Phe pilin family
LGL85_02860	COG3725	Membrane protein required for beta-lactamase induction
LGL85_02865	COG1113	amino acid transport
LGL85_02870	COG2186	Transcriptional regulator
LGL85_02875	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LGL85_02880	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL85_02885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL85_02895	COG1049	propionate catabolic process, 2-methylcitrate cycle
LGL85_02900	COG3112	Uncharacterised protein family (UPF0231)
LGL85_02915	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGL85_02925	COG2132	Multicopper oxidase
LGL85_02935	COG0288	reversible hydration of carbon dioxide
LGL85_02940	COG1131	(ABC) transporter
LGL85_02945	COG0842	Transport permease protein
LGL85_02950	COG0726	polysaccharide deacetylase
LGL85_02955	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGL85_02960	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGL85_02965	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGL85_02970	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGL85_02975	COG0617	tRNA 3'-terminal CCA addition
LGL85_02990	COG1489	DNA binding
LGL85_02995	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGL85_03000	COG1643	Atp-dependent helicase
LGL85_03005	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL85_03010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGL85_03020	COG0316	Belongs to the HesB IscA family
LGL85_03025	COG2860	membrane
LGL85_03035	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL85_03040	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL85_03045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL85_03055	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL85_03060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL85_03065	COG3956	TIGRFAM MazG family protein
LGL85_03070	COG0504	CTP synthase activity
LGL85_03080	COG0602	queuosine metabolic process
LGL85_03085	COG0720	synthase
LGL85_03090	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGL85_03100	COG0175	sulfate reduction
LGL85_03115	COG2234	aminopeptidase activity
LGL85_03120	COG1648	precorrin-2 dehydrogenase activity
LGL85_03120	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGL85_03125	COG0175	sulfate reduction
LGL85_03130	COG2895	sulfate adenylyltransferase (ATP) activity
LGL85_03135	COG0529	Catalyzes the synthesis of activated sulfate
LGL85_03145	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGL85_03155	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGL85_03160	COG0585	pseudouridine synthase activity
LGL85_03165	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGL85_03175	COG4942	peptidase
LGL85_03175	COG1388	LysM domain
LGL85_03180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGL85_03185	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGL85_03260	COG2205	protein histidine kinase activity
LGL85_03285	COG0741	lytic transglycosylase activity
LGL85_03415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL85_03435	COG3397	chitin binding
LGL85_03445	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGL85_03490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL85_03500	COG3031	protein transport across the cell outer membrane
LGL85_03525	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL85_03525	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL85_03540	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGL85_03545	COG2137	regulation of response to DNA damage stimulus
LGL85_03550	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGL85_03555	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGL85_03595	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL85_03600	COG1238	metal cluster binding
LGL85_03605	COG2918	glutathione biosynthetic process
LGL85_03610	COG1854	S-ribosylhomocysteine lyase activity
LGL85_03615	COG4536	flavin adenine dinucleotide binding
LGL85_03620	COG4137	Cytochrome C assembly protein
LGL85_03625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGL85_03635	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGL85_03640	COG0336	Belongs to the RNA methyltransferase TrmD family
LGL85_03645	COG0335	large ribosomal subunit rRNA binding
LGL85_03650	COG3137	Salt-induced outer membrane protein
LGL85_03655	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL85_03660	COG3279	Response regulator of the LytR AlgR family
LGL85_03665	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL85_03670	COG1605	Chorismate mutase
LGL85_03670	COG0287	Prephenate dehydrogenase
LGL85_03675	COG1605	Chorismate mutase
LGL85_03675	COG0077	Prephenate dehydratase
LGL85_03685	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGL85_03690	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL85_03695	COG0564	pseudouridine synthase activity
LGL85_03700	COG1496	oxidoreductase activity
LGL85_03705	COG0542	response to heat
LGL85_03740	COG3021	interspecies interaction between organisms
LGL85_03745	COG0741	lytic transglycosylase activity
LGL85_03745	COG1388	LysM domain
LGL85_03755	COG2226	methyltransferase
LGL85_03765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL85_03775	COG1960	acyl-CoA dehydrogenase activity
LGL85_03780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL85_03785	COG0121	glutamine amidotransferase
LGL85_03790	COG3034	peptidoglycan biosynthetic process
LGL85_03800	COG1805	sodium ion transport
LGL85_03805	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL85_03810	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL85_03815	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL85_03825	COG1477	protein flavinylation
LGL85_03830	COG2991	Protein conserved in bacteria
LGL85_03840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL85_03845	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGL85_03850	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LGL85_03855	COG1073	alpha beta
LGL85_03870	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGL85_03905	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL85_03930	COG4126	flavin adenine dinucleotide binding
LGL85_03940	COG2974	May be involved in recombination
LGL85_03945	COG1940	carbohydrate kinase activity
LGL85_03950	COG0419	ATPase involved in DNA repair
LGL85_03955	COG0420	3'-5' exonuclease activity
LGL85_03960	COG0745	RESPONSE REGULATOR receiver
LGL85_03965	COG5002	protein histidine kinase activity
LGL85_03980	COG1113	amino acid transport
LGL85_03985	COG0366	Alpha amylase catalytic
LGL85_03990	COG0300	oxidoreductase activity
LGL85_03995	COG0450	alkyl hydroperoxide reductase
LGL85_04000	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LGL85_04015	COG1862	Preprotein translocase
LGL85_04020	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL85_04025	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL85_04030	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGL85_04035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL85_04035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL85_04040	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGL85_04050	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGL85_04055	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGL85_04060	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGL85_04065	COG0142	geranyltranstransferase activity
LGL85_04100	COG0693	protein deglycase activity
LGL85_04105	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGL85_04110	COG1666	GTP binding
LGL85_04115	COG2814	Major facilitator Superfamily
LGL85_04125	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGL85_04130	COG1845	cytochrome c oxidase, subunit III
LGL85_04135	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGL85_04140	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGL85_04150	COG2223	nitrite transmembrane transporter activity
LGL85_04155	COG3056	Lipoprotein
LGL85_04160	COG0271	Belongs to the BolA IbaG family
LGL85_04170	COG0740	serine-type endopeptidase activity
LGL85_04175	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGL85_04180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL85_04185	COG0776	regulation of translation
LGL85_04190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL85_04195	COG1555	photosystem II stabilization
LGL85_04200	COG0824	Thioesterase
LGL85_04205	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGL85_04210	COG4533	DNA binding
LGL85_04225	COG1522	sequence-specific DNA binding
LGL85_04230	COG1132	(ABC) transporter
LGL85_04235	COG1132	(ABC) transporter
LGL85_04240	COG0347	Belongs to the P(II) protein family
LGL85_04250	COG1946	Acyl-CoA thioesterase
LGL85_04255	COG3695	enzyme binding
LGL85_04280	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL85_04285	COG0254	rRNA binding
LGL85_04290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL85_04295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL85_04300	COG1309	transcriptional regulator
LGL85_04305	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGL85_04310	COG1196	nuclear chromosome segregation
LGL85_04310	COG3264	Mechanosensitive ion channel
LGL85_04325	COG2832	Protein of unknown function (DUF454)
LGL85_04330	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGL85_04370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGL85_04375	COG0326	Molecular chaperone. Has ATPase activity
LGL85_04390	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL85_04395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL85_04400	COG4651	solute:proton antiporter activity
LGL85_04400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL85_04405	COG0737	Belongs to the 5'-nucleotidase family
LGL85_04410	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGL85_04415	COG3735	TraB family
LGL85_04420	COG2217	Heavy metal translocating P-type atpase
LGL85_04425	COG0789	Transcriptional regulator
LGL85_04430	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGL85_04435	COG0330	HflC and HflK could
LGL85_04440	COG3118	belongs to the thioredoxin family
LGL85_04445	COG0300	oxidoreductase activity
LGL85_04450	COG2755	lipolytic protein G-D-S-L family
LGL85_04455	COG4181	ATPase activity
LGL85_04460	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGL85_04465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGL85_04470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGL85_04475	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL85_04480	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL85_04510	COG3188	usher protein
LGL85_04515	COG3121	Chaperone
LGL85_04545	COG2501	S4 domain
LGL85_04550	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGL85_04565	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGL85_04570	COG1393	Belongs to the ArsC family
LGL85_04580	COG1022	Amp-dependent synthetase and ligase
LGL85_04605	COG3038	cytochrome b561
LGL85_04635	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGL85_04645	COG1215	transferase activity, transferring glycosyl groups
LGL85_04665	COG3250	beta-galactosidase activity
LGL85_04680	COG1309	transcriptional regulator
LGL85_04710	COG2197	response regulator
LGL85_04715	COG1278	Cold shock
LGL85_04735	COG3706	GGDEF domain
LGL85_04745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGL85_04755	COG2921	Belongs to the UPF0250 family
LGL85_04760	COG1686	Belongs to the peptidase S11 family
LGL85_04765	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL85_04770	COG0772	Belongs to the SEDS family
LGL85_04775	COG0768	penicillin binding
LGL85_04780	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGL85_04785	COG0799	negative regulation of ribosome biogenesis
LGL85_04790	COG0582	viral genome integration into host DNA
LGL85_04905	COG0305	Participates in initiation and elongation during chromosome replication
LGL85_04955	COG3646	Phage regulatory protein
LGL85_04980	COG3567	Phage-associated protein, HI1409 family
LGL85_04985	COG2369	cell adhesion
LGL85_05115	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL85_05125	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGL85_05130	COG1466	dna polymerase III delta subunit
LGL85_05135	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LGL85_05145	COG2888	peptidyl-tyrosine sulfation
LGL85_05150	COG1126	abc transporter atp-binding protein
LGL85_05155	COG0765	amino acid transport
LGL85_05160	COG0765	amino acid transport
LGL85_05170	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGL85_05175	COG4535	Mg2 and Co2 transporter CorC
LGL85_05180	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGL85_05185	COG1702	phosphate starvation-inducible protein PhoH
LGL85_05190	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGL85_05195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL85_05230	COG0367	asparagine synthase
LGL85_05235	COG0647	UMP catabolic process
LGL85_05240	COG1940	carbohydrate kinase activity
LGL85_05240	COG1846	Transcriptional regulator
LGL85_05245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL85_05255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_05255	COG2190	(PTS) system
LGL85_05255	COG1263	PTS System
LGL85_05280	COG0735	belongs to the Fur family
LGL85_05290	COG0840	transmembrane signaling receptor activity
LGL85_05300	COG0596	Alpha beta hydrolase
LGL85_05305	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LGL85_05310	COG0033	Phosphoglucomutase
LGL85_05320	COG0745	RESPONSE REGULATOR receiver
LGL85_05325	COG2205	protein histidine kinase activity
LGL85_05330	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LGL85_05335	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGL85_05355	COG3272	Protein of unknown function (DUF1722)
LGL85_05360	COG0415	Belongs to the DNA photolyase family
LGL85_05365	COG5212	phosphodiesterase
LGL85_05370	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGL85_05375	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGL85_05380	COG1984	allophanate hydrolase subunit 2
LGL85_05385	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGL85_05420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGL85_05425	COG1053	succinate dehydrogenase
LGL85_05430	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL85_05435	COG0567	Dehydrogenase, E1 component
LGL85_05440	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL85_05445	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL85_05450	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGL85_05455	COG0737	Belongs to the 5'-nucleotidase family
LGL85_05460	COG1271	oxidase subunit
LGL85_05465	COG1294	oxidase, subunit
LGL85_05470	COG4890	Cyd operon protein YbgT
LGL85_05475	COG3790	cyd operon protein YbgE
LGL85_05480	COG0824	Thioesterase
LGL85_05485	COG0811	peptide transport
LGL85_05490	COG0848	biopolymer transport protein
LGL85_05495	COG3064	Membrane
LGL85_05495	COG3064	Membrane
LGL85_05500	COG0823	Involved in the tonB-independent uptake of proteins
LGL85_05505	COG2885	chlorophyll binding
LGL85_05510	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LGL85_05550	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGL85_05560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_05560	COG2205	protein histidine kinase activity
LGL85_05570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL85_05575	COG0588	phosphoglycerate mutase activity
LGL85_05585	COG2017	converts alpha-aldose to the beta-anomer
LGL85_05595	COG1085	galactose-1-phosphate uridylyltransferase
LGL85_05600	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGL85_05615	COG3585	molybdate ion transport
LGL85_05615	COG2005	Transcriptional regulator
LGL85_05625	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGL85_05630	COG4149	molybdate abc transporter
LGL85_05640	COG0561	phosphatase activity
LGL85_05645	COG2706	6-phosphogluconolactonase activity
LGL85_05660	COG0156	8-amino-7-oxononanoate synthase activity
LGL85_05665	COG2226	methyltransferase
LGL85_05680	COG0556	nucleotide-excision repair
LGL85_05685	COG4628	conserved protein (DUF2132)
LGL85_05700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL85_05705	COG1120	ATPase activity
LGL85_05710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGL85_05715	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGL85_05725	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGL85_05730	COG0314	molybdopterin synthase activity
LGL85_05735	COG0670	Belongs to the BI1 family
LGL85_05740	COG0842	Transport permease protein
LGL85_05745	COG0842	Transport permease protein
LGL85_05750	COG1131	(ABC) transporter
LGL85_05755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL85_05760	COG1309	transcriptional regulator
LGL85_05765	COG0513	Belongs to the DEAD box helicase family
LGL85_05770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL85_05780	COG1686	Belongs to the peptidase S11 family
LGL85_05785	COG0277	FAD linked oxidase domain protein
LGL85_05805	COG2261	transglycosylase associated protein
LGL85_05815	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LGL85_05825	COG3639	organic phosphonate transmembrane transporter activity
LGL85_05830	COG4807	Protein conserved in bacteria
LGL85_05835	COG2897	thiosulfate sulfurtransferase activity
LGL85_05840	COG1732	Glycine betaine
LGL85_05845	COG1174	glycine betaine transport
LGL85_05850	COG1125	glycine betaine transport
LGL85_05855	COG1174	glycine betaine transport
LGL85_05860	COG0531	amino acid
LGL85_05865	COG1982	Orn Lys Arg decarboxylase major
LGL85_05875	COG0697	spore germination
LGL85_05890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGL85_05895	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LGL85_05900	COG1126	abc transporter atp-binding protein
LGL85_05905	COG0765	amino acid transport
LGL85_05910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_05930	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGL85_05935	COG2239	Acts as a magnesium transporter
LGL85_05940	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL85_05945	COG0488	(ABC) transporter
LGL85_05950	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL85_05955	COG0303	'Molybdopterin
LGL85_05975	COG0583	DNA-binding transcription factor activity
LGL85_05980	COG0477	Major facilitator Superfamily
LGL85_05985	COG0302	gtp cyclohydrolase
LGL85_05990	COG2311	Membrane
LGL85_06015	COG2949	membrane
LGL85_06020	COG0281	malic enzyme
LGL85_06030	COG0583	DNA-binding transcription factor activity
LGL85_06040	COG1346	cytolysis
LGL85_06045	COG1380	Effector of murein hydrolase LrgA
LGL85_06055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL85_06055	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL85_06060	COG0489	protein tyrosine kinase activity
LGL85_06065	COG0572	uridine kinase
LGL85_06070	COG0717	Belongs to the dCTP deaminase family
LGL85_06075	COG2982	Protein involved in outer membrane biogenesis
LGL85_06080	COG3069	C4-dicarboxylate transmembrane transporter activity
LGL85_06085	COG1253	flavin adenine dinucleotide binding
LGL85_06090	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL85_06095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL85_06100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGL85_06110	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGL85_06110	COG0140	phosphoribosyl-ATP diphosphatase activity
LGL85_06120	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGL85_06130	COG0131	Imidazoleglycerol-phosphate dehydratase
LGL85_06130	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL85_06135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGL85_06140	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGL85_06155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL85_06160	COG0625	glutathione transferase activity
LGL85_06175	COG0626	cystathionine gamma-synthase activity
LGL85_06185	COG1686	Belongs to the peptidase S11 family
LGL85_06190	COG1760	l-serine dehydratase
LGL85_06195	COG0814	amino acid
LGL85_06200	COG1349	DNA-binding transcription factor activity
LGL85_06210	COG0671	phosphoesterase, PA-phosphatase related
LGL85_06220	COG0569	domain protein
LGL85_06220	COG2985	domain, Protein
LGL85_06240	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGL85_06245	COG3842	ATPase activity
LGL85_06250	COG1176	ABC-type spermidine putrescine transport system, permease component I
LGL85_06255	COG1177	transmembrane transport
LGL85_06270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_06275	COG4160	amino acid transport
LGL85_06280	COG4215	(ABC) transporter
LGL85_06285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_06290	COG1126	abc transporter atp-binding protein
LGL85_06300	COG0393	Putative heavy-metal-binding
LGL85_06305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL85_06310	COG0702	epimerase
LGL85_06315	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LGL85_06320	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL85_06325	COG1151	hydroxylamine reductase activity
LGL85_06330	COG2431	L-lysine efflux transmembrane transporter activity
LGL85_06335	COG3593	DNA synthesis involved in DNA repair
LGL85_06340	COG2990	Protein conserved in bacteria
LGL85_06345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL85_06355	COG1278	Cold shock
LGL85_06360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGL85_06365	COG0542	response to heat
LGL85_06370	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGL85_06380	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGL85_06390	COG0492	ferredoxin-NADP+ reductase activity
LGL85_06395	COG1522	sequence-specific DNA binding
LGL85_06400	COG1674	ftsk spoiiie
LGL85_06400	COG3107	peptidoglycan biosynthetic process
LGL85_06405	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGL85_06410	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGL85_06415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGL85_06420	COG2814	Major facilitator Superfamily
LGL85_06425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGL85_06430	COG1882	Formate acetyltransferase
LGL85_06435	COG2116	formate transmembrane transporter activity
LGL85_06440	COG1944	ATP diphosphatase activity
LGL85_06445	COG0252	asparaginase activity
LGL85_06455	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGL85_06465	COG0539	negative regulation of cytoplasmic translation
LGL85_06475	COG0658	competence protein
LGL85_06475	COG2333	competence protein COMEC
LGL85_06485	COG1663	tetraacyldisaccharide 4'-kinase activity
LGL85_06490	COG5383	Protein conserved in bacteria
LGL85_06500	COG1278	Cold shock
LGL85_06505	COG2835	tetraacyldisaccharide 4'-kinase activity
LGL85_06510	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LGL85_06515	COG3173	Aminoglycoside phosphotransferase
LGL85_06520	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LGL85_06525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL85_06530	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LGL85_06540	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LGL85_06545	COG2989	Protein conserved in bacteria
LGL85_06550	COG3108	Peptidase M15
LGL85_06555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGL85_06560	COG1448	Aminotransferase
LGL85_06575	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGL85_06580	COG0308	aminopeptidase N
LGL85_06585	COG0167	dihydroorotate dehydrogenase activity
LGL85_06595	COG0633	Ferredoxin
LGL85_06595	COG3217	Mosc domain protein beta barrel domain protein
LGL85_06600	COG0116	Belongs to the methyltransferase superfamily
LGL85_06600	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL85_06605	COG0488	(ABC) transporter
LGL85_06610	COG2995	paraquat-inducible protein a
LGL85_06615	COG3008	intermembrane lipid transfer
LGL85_06615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL85_06620	COG3009	Protein conserved in bacteria
LGL85_06625	COG3130	regulation of translation
LGL85_06630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGL85_06635	COG1067	ATP-dependent peptidase activity
LGL85_06640	COG3120	sequence-specific DNA binding
LGL85_06650	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LGL85_06655	COG3070	regulator of competence-specific genes
LGL85_06660	COG1289	transmembrane transporter activity
LGL85_06665	COG3304	Inner membrane component domain
LGL85_06670	COG0210	DNA helicase
LGL85_06675	COG1803	Methylglyoxal synthase
LGL85_06685	COG1832	CoA-binding protein
LGL85_06690	COG3785	DNA binding
LGL85_06695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL85_06700	COG1254	Belongs to the acylphosphatase family
LGL85_06705	COG2920	part of a sulfur-relay system
LGL85_06715	COG0288	reversible hydration of carbon dioxide
LGL85_06735	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LGL85_06740	COG2943	transferase activity, transferring hexosyl groups
LGL85_06755	COG0675	Transposase, IS605 OrfB family
LGL85_06770	COG1560	Kdo2-lipid A biosynthetic process
LGL85_06780	COG0628	permease
LGL85_06805	COG0418	dihydroorotase activity
LGL85_06810	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LGL85_06820	COG1530	ribonuclease E activity
LGL85_06825	COG0564	pseudouridine synthase activity
LGL85_06830	COG0424	maF-like protein
LGL85_06835	COG1399	metal-binding, possibly nucleic acid-binding protein
LGL85_06840	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGL85_06850	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGL85_06855	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGL85_06865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL85_06870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL85_06875	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGL85_06880	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGL85_06885	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGL85_06890	COG0470	DNA polymerase III
LGL85_06895	COG0084	hydrolase, TatD family'
LGL85_06900	COG1263	PTS System
LGL85_06900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_06905	COG0537	adenosine 5'-monophosphoramidase activity
LGL85_06910	COG5633	Lipoprotein
LGL85_06915	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LGL85_06930	COG3150	esterase
LGL85_06935	COG1252	NADH dehydrogenase
LGL85_06940	COG3134	Outer membrane lipoprotein
LGL85_06945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGL85_06950	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL85_06960	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL85_06980	COG2850	peptidyl-arginine hydroxylation
LGL85_06985	COG2205	protein histidine kinase activity
LGL85_06990	COG0745	RESPONSE REGULATOR receiver
LGL85_07000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGL85_07005	COG2915	High frequency lysogenization protein hflD homolog
LGL85_07010	COG0482	sulfurtransferase activity
LGL85_07020	COG1187	pseudouridine synthase activity
LGL85_07025	COG0538	isocitrate dehydrogenase activity
LGL85_07030	COG0582	viral genome integration into host DNA
LGL85_07070	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL85_07075	COG5532	Uncharacterized conserved protein (DUF2303)
LGL85_07125	COG1802	Transcriptional regulator
LGL85_07125	COG4626	Terminase
LGL85_07130	COG0270	DNA (cytosine-5-)-methyltransferase activity
LGL85_07160	COG1403	HNH endonuclease
LGL85_07195	COG3179	chitinase
LGL85_07205	COG3646	Phage regulatory protein
LGL85_07220	COG1802	Transcriptional regulator
LGL85_07220	COG4626	Terminase
LGL85_07300	COG1674	ftsk spoiiie
LGL85_07300	COG1178	ABC-type Fe3 transport system permease component
LGL85_07345	COG2771	luxR family
LGL85_07350	COG3916	Acyl-homoserine-lactone synthase
LGL85_07355	COG2723	6-phospho-beta-galactosidase activity
LGL85_07365	COG0339	signal peptide processing
LGL85_07370	COG0840	transmembrane signaling receptor activity
LGL85_07395	COG0675	Transposase, IS605 OrfB family
LGL85_07405	COG4565	transcriptional regulatory protein
LGL85_07410	COG3290	protein histidine kinase activity
LGL85_07415	COG0471	metal ion transport
LGL85_07460	COG4977	sequence-specific DNA binding
LGL85_07465	COG1702	phosphate starvation-inducible protein PhoH
LGL85_07470	COG0387	Pfam Sodium calcium exchanger
LGL85_07475	COG2375	cellular response to nickel ion
LGL85_07480	COG3850	Histidine kinase
LGL85_07490	COG1294	oxidase, subunit
LGL85_07495	COG1271	oxidase subunit
LGL85_07500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL85_07505	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGL85_07510	COG3138	arginine N-succinyltransferase
LGL85_07520	COG3724	N-succinylarginine dihydrolase activity
LGL85_07540	COG1228	amidohydrolase
LGL85_07550	COG0402	S-adenosylhomocysteine deaminase activity
LGL85_07570	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL85_07575	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LGL85_07580	COG3383	formate dehydrogenase (NAD+) activity
LGL85_07585	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL85_07590	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGL85_07600	COG3260	NADH ubiquinone oxidoreductase 20
LGL85_07605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_07610	COG3261	NADH dehydrogenase
LGL85_07610	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LGL85_07615	COG0650	Formate hydrogenlyase subunit 4
LGL85_07620	COG0651	ATP synthesis coupled electron transport
LGL85_07625	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL85_07635	COG0375	protein maturation
LGL85_07640	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LGL85_07645	COG0298	carbon dioxide binding
LGL85_07650	COG0409	Hydrogenase expression formation protein
LGL85_07655	COG0309	Hydrogenase expression formation protein (HypE)
LGL85_07690	COG2207	Transcriptional regulator
LGL85_07690	COG3708	Transcriptional regulator
LGL85_07695	COG0012	GTP binding
LGL85_07705	COG0193	aminoacyl-tRNA hydrolase activity
LGL85_07715	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGL85_07725	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGL85_07730	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGL85_07735	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGL85_07740	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL85_07755	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LGL85_07760	COG0659	secondary active sulfate transmembrane transporter activity
LGL85_07765	COG3706	GGDEF domain
LGL85_07790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL85_07800	COG3381	protein complex oligomerization
LGL85_07820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL85_07830	COG0673	inositol 2-dehydrogenase activity
LGL85_07835	COG0728	peptidoglycan biosynthetic process
LGL85_07870	COG3102	Protein conserved in bacteria
LGL85_07875	COG3142	Participates in the control of copper homeostasis
LGL85_07890	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LGL85_07895	COG1801	Protein of unknown function DUF72
LGL85_07905	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGL85_07910	COG0494	nUDIX hydrolase
LGL85_07920	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LGL85_07930	COG2255	four-way junction helicase activity
LGL85_07935	COG3104	oligopeptide transport
LGL85_07940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL85_07945	COG1121	(ABC) transporter
LGL85_07950	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LGL85_07955	COG0739	heme binding
LGL85_07960	COG1560	Kdo2-lipid A biosynthetic process
LGL85_07965	COG0469	pyruvate kinase activity
LGL85_07970	COG1737	Transcriptional regulator
LGL85_07975	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGL85_07980	COG0800	Aldolase
LGL85_07990	COG2076	Multidrug Resistance protein
LGL85_07995	COG0251	oxidation-reduction process
LGL85_08000	COG1199	ATP-dependent helicase activity
LGL85_08005	COG1214	PFAM Peptidase M22, glycoprotease
LGL85_08010	COG3065	identical protein binding
LGL85_08015	COG0318	PFAM AMP-dependent synthetase and ligase
LGL85_08020	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LGL85_08025	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LGL85_08030	COG2894	cell division
LGL85_08035	COG0850	regulation of cytokinetic process
LGL85_08040	COG3100	YcgL domain-containing protein
LGL85_08045	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGL85_08050	COG2983	Belongs to the UPF0260 family
LGL85_08070	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL85_08080	COG2719	SpoVR family
LGL85_08085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGL85_08090	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGL85_08095	COG2814	Major facilitator Superfamily
LGL85_08105	COG2199	diguanylate cyclase activity
LGL85_08105	COG2200	EAL domain
LGL85_08105	COG2202	Pas domain
LGL85_08125	COG2718	Belongs to the UPF0229 family
LGL85_08130	COG2766	serine protein kinase
LGL85_08140	COG3713	MltA-interacting MipA family protein
LGL85_08145	COG2194	sulfuric ester hydrolase activity
LGL85_08160	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL85_08165	COG3139	Protein of unknown function (DUF1315)
LGL85_08170	COG1335	isochorismatase
LGL85_08175	COG0252	asparaginase activity
LGL85_08180	COG0616	signal peptide processing
LGL85_08185	COG0778	Nitroreductase
LGL85_08195	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL85_08205	COG0494	nUDIX hydrolase
LGL85_08210	COG0708	Exodeoxyribonuclease III
LGL85_08240	COG0788	formyltetrahydrofolate deformylase activity
LGL85_08250	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGL85_08255	COG0745	RESPONSE REGULATOR receiver
LGL85_08275	COG1454	alcohol dehydrogenase
LGL85_08275	COG1012	belongs to the aldehyde dehydrogenase family
LGL85_08285	COG2095	MarC family integral membrane protein
LGL85_08290	COG4166	transmembrane transport
LGL85_08305	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL85_08320	COG3099	Belongs to the UPF0263 family
LGL85_08325	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL85_08345	COG2350	Protein conserved in bacteria
LGL85_08360	COG3710	Transcriptional regulator
LGL85_08395	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LGL85_08420	COG0727	PFAM Uncharacterised protein family (UPF0153)
LGL85_08425	COG3047	cAMP biosynthetic process
LGL85_08440	COG0133	tryptophan synthase activity
LGL85_08445	COG0134	indole-3-glycerol-phosphate synthase activity
LGL85_08445	COG0135	phosphoribosylanthranilate isomerase activity
LGL85_08455	COG0512	Glutamine amidotransferase of anthranilate synthase
LGL85_08465	COG0613	PHP domain protein
LGL85_08470	COG0009	L-threonylcarbamoyladenylate synthase
LGL85_08485	COG1187	pseudouridine synthase activity
LGL85_08495	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_08500	COG0616	signal peptide processing
LGL85_08515	COG0583	DNA-binding transcription factor activity
LGL85_08530	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGL85_08540	COG0671	phosphoesterase, PA-phosphatase related
LGL85_08545	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LGL85_08550	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LGL85_08570	COG0023	Translation Initiation Factor
LGL85_08580	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL85_08585	COG3447	MASE1 domain protein
LGL85_08585	COG5002	protein histidine kinase activity
LGL85_08585	COG5001	Diguanylate cyclase
LGL85_08590	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LGL85_08595	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGL85_08605	COG4659	FMN binding
LGL85_08615	COG3708	Transcriptional regulator
LGL85_08615	COG2207	Transcriptional regulator
LGL85_08630	COG4657	Part of a membrane complex involved in electron transport
LGL85_08640	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGL85_08650	COG0673	inositol 2-dehydrogenase activity
LGL85_08655	COG0385	Bile acid
LGL85_08660	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGL85_08665	COG5339	Protein conserved in bacteria
LGL85_08670	COG1482	cell wall glycoprotein biosynthetic process
LGL85_08675	COG0114	fumarate hydratase activity
LGL85_08685	COG1940	carbohydrate kinase activity
LGL85_08690	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGL85_08710	COG1742	UPF0060 membrane protein
LGL85_08715	COG4221	oxidoreductase activity
LGL85_08720	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL85_08740	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL85_08780	COG1011	Hydrolase
LGL85_08790	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGL85_08795	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGL85_08800	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL85_08805	COG0589	response to stress
LGL85_08835	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGL85_08840	COG3623	hexulose-6-phosphate isomerase
LGL85_08845	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LGL85_08850	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LGL85_08860	COG0531	amino acid
LGL85_08870	COG0745	RESPONSE REGULATOR receiver
LGL85_08875	COG2205	protein histidine kinase activity
LGL85_08890	COG2207	Transcriptional regulator
LGL85_08895	COG1881	PFAM PEBP family protein
LGL85_08905	COG3591	Belongs to the peptidase S1B family
LGL85_08910	COG1643	Atp-dependent helicase
LGL85_08915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGL85_08920	COG3784	Protein of unknown function (DUF1318)
LGL85_08935	COG2911	Protein conserved in bacteria
LGL85_08940	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGL85_08945	COG3187	Heat shock protein
LGL85_08950	COG3042	response to heat
LGL85_08955	COG1285	pathogenesis
LGL85_08965	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGL85_08965	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_08965	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGL85_08965	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGL85_08980	COG4166	transmembrane transport
LGL85_08985	COG2866	Carboxypeptidase
LGL85_08990	COG4948	Mandelate Racemase Muconate Lactonizing
LGL85_08995	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGL85_09005	COG5642	Protein of unknown function (DUF2384)
LGL85_09010	COG5654	RES domain protein
LGL85_09015	COG3768	UPF0283 membrane protein
LGL85_09020	COG3106	COG3106 Predicted ATPase
LGL85_09030	COG1983	PspC domain protein
LGL85_09040	COG1842	Phage shock protein A
LGL85_09045	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LGL85_09060	COG4166	transmembrane transport
LGL85_09070	COG4171	peptide transport system, permease
LGL85_09075	COG4172	Belongs to the ABC transporter superfamily
LGL85_09080	COG4172	Belongs to the ABC transporter superfamily
LGL85_09090	COG3104	oligopeptide transport
LGL85_09100	COG0484	heat shock protein binding
LGL85_09145	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGL85_09150	COG3133	Outer membrane lipoprotein
LGL85_09155	COG1846	Transcriptional regulator
LGL85_09165	COG4989	oxidoreductase activity
LGL85_09170	COG3313	Fe-S protein
LGL85_09175	COG2194	sulfuric ester hydrolase activity
LGL85_09180	COG1309	transcriptional regulator
LGL85_09185	COG1902	pentaerythritol trinitrate reductase activity
LGL85_09200	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGL85_09205	COG0791	NLP P60 protein
LGL85_09210	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL85_09220	COG1609	Transcriptional regulator
LGL85_09225	COG0583	DNA-binding transcription factor activity
LGL85_09230	COG2814	Major facilitator Superfamily
LGL85_09235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL85_09240	COG0307	riboflavin synthase, alpha
LGL85_09275	COG1376	ErfK ybiS ycfS ynhG family protein
LGL85_09275	COG1388	LysM domain
LGL85_09280	COG2166	iron-sulfur cluster assembly
LGL85_09290	COG0719	Fe-S assembly protein
LGL85_09295	COG0396	ATPase activity
LGL85_09300	COG0719	Fe-S assembly protein
LGL85_09305	COG0316	Belongs to the HesB IscA family
LGL85_09310	COG2050	protein possibly involved in aromatic compounds catabolism
LGL85_09315	COG0277	FAD linked oxidase domain protein
LGL85_09315	COG0247	lactate metabolic process
LGL85_09320	COG0628	permease
LGL85_09330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL85_09330	COG0574	Belongs to the PEP-utilizing enzyme family
LGL85_09335	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGL85_09340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL85_09350	COG4771	TonB-dependent receptor
LGL85_09355	COG3720	iron ion transport
LGL85_09360	COG4558	Periplasmic binding protein
LGL85_09365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL85_09370	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LGL85_09380	COG0095	Lipoate-protein ligase
LGL85_09385	COG0791	NLP P60 protein
LGL85_09390	COG2076	Multidrug Resistance protein
LGL85_09395	COG2076	Multidrug Resistance protein
LGL85_09400	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGL85_09415	COG0463	Glycosyl transferase, family 2
LGL85_09420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL85_09430	COG4139	cobalamin transport
LGL85_09475	COG2184	nucleotidyltransferase activity
LGL85_09490	COG2314	TM2 domain
LGL85_09495	COG0776	regulation of translation
LGL85_09570	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGL85_09575	COG1121	(ABC) transporter
LGL85_09580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL85_09585	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL85_09590	COG3001	Fructosamine kinase
LGL85_09600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL85_09605	COG1988	membrane-bound metal-dependent
LGL85_09610	COG1823	symporter activity
LGL85_09615	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL85_09625	COG2814	Major facilitator Superfamily
LGL85_09635	COG0501	Belongs to the peptidase M48B family
LGL85_09640	COG0793	Belongs to the peptidase S41A family
LGL85_09650	COG1956	GAF domain-containing protein
LGL85_09655	COG2995	paraquat-inducible protein a
LGL85_09660	COG3008	intermembrane lipid transfer
LGL85_09665	COG5001	Diguanylate cyclase
LGL85_09665	COG4251	negative regulation of phosphorylation
LGL85_09665	COG3706	GGDEF domain
LGL85_09665	COG2203	Gaf domain
LGL85_09745	COG1276	copper resistance
LGL85_09750	COG2372	response to copper ion
LGL85_09755	COG1528	Iron-storage protein
LGL85_09770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL85_09775	COG1770	oligopeptidase
LGL85_09785	COG3097	Belongs to the UPF0267 family
LGL85_09790	COG3141	response to X-ray
LGL85_09795	COG0513	Belongs to the DEAD box helicase family
LGL85_09815	COG0494	nUDIX hydrolase
LGL85_09820	COG1760	l-serine dehydratase
LGL85_09825	COG1253	flavin adenine dinucleotide binding
LGL85_09830	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_09830	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL85_09835	COG3715	PTS system
LGL85_09840	COG3716	PTS system mannose fructose sorbose family IID component
LGL85_09845	COG4811	Protein of unknown function (DUF986)
LGL85_09850	COG1971	Probably functions as a manganese efflux pump
LGL85_09870	COG1960	acyl-CoA dehydrogenase activity
LGL85_09880	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGL85_09910	COG2226	methyltransferase
LGL85_09915	COG0768	penicillin binding
LGL85_09920	COG1496	oxidoreductase activity
LGL85_09940	COG1113	amino acid transport
LGL85_09975	COG2207	Transcriptional regulator
LGL85_09995	COG1132	(ABC) transporter
LGL85_10005	COG2203	Gaf domain
LGL85_10005	COG3706	GGDEF domain
LGL85_10005	COG4251	negative regulation of phosphorylation
LGL85_10005	COG5001	Diguanylate cyclase
LGL85_10025	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGL85_10045	COG1278	Cold shock
LGL85_10050	COG1278	Cold shock
LGL85_10055	COG1278	Cold shock
LGL85_10070	COG1917	Cupin 2, conserved barrel domain protein
LGL85_10070	COG2169	Transcriptional regulator
LGL85_10075	COG1447	Phosphotransferase system cellobiose-specific component IIA
LGL85_10080	COG2723	6-phospho-beta-galactosidase activity
LGL85_10085	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL85_10090	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL85_10095	COG1187	pseudouridine synthase activity
LGL85_10105	COG3122	Protein conserved in bacteria
LGL85_10110	COG1757	Na H antiporter
LGL85_10125	COG2235	arginine
LGL85_10140	COG0076	glutamate decarboxylase activity
LGL85_10145	COG0531	amino acid
LGL85_10180	COG2153	protein acetylation
LGL85_10185	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGL85_10215	COG0840	transmembrane signaling receptor activity
LGL85_10220	COG2801	Transposase and inactivated derivatives
LGL85_10245	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGL85_10250	COG0322	excinuclease ABC activity
LGL85_10255	COG2197	response regulator
LGL85_10280	COG1113	amino acid transport
LGL85_10290	COG0531	amino acid
LGL85_10295	COG3710	Transcriptional regulator
LGL85_10300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL85_10305	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL85_10305	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL85_10305	COG0506	proline dehydrogenase activity
LGL85_10310	COG1126	abc transporter atp-binding protein
LGL85_10315	COG0765	amino acid transport
LGL85_10320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_10325	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGL85_10335	COG1191	sigma factor activity
LGL85_10375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGL85_10380	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL85_10395	COG1677	Flagellar hook-basal body complex protein FliE
LGL85_10405	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGL85_10410	COG1317	bacterial-type flagellum organization
LGL85_10415	COG1157	protein secretion by the type III secretion system
LGL85_10430	COG1580	Controls the rotational direction of flagella during chemotaxis
LGL85_10510	COG1558	bacterial-type flagellum-dependent cell motility
LGL85_10515	COG1815	bacterial-type flagellum-dependent cell motility
LGL85_10525	COG2747	anti-sigma28 factor FlgM
LGL85_10530	COG3418	PFAM FlgN family protein
LGL85_10540	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL85_10545	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL85_10550	COG1404	Belongs to the peptidase S8 family
LGL85_10550	COG4935	Belongs to the peptidase S8 family
LGL85_10555	COG2197	response regulator
LGL85_10570	COG3188	usher protein
LGL85_10575	COG3121	Chaperone
LGL85_10585	COG3539	Fimbrial protein
LGL85_10615	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LGL85_10620	COG0745	RESPONSE REGULATOR receiver
LGL85_10630	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGL85_10635	COG0840	transmembrane signaling receptor activity
LGL85_10640	COG0840	transmembrane signaling receptor activity
LGL85_10645	COG0835	chemotaxis
LGL85_10650	COG2198	Histidine kinase
LGL85_10650	COG0643	Histidine kinase
LGL85_10655	COG1360	Flagellar Motor Protein
LGL85_10675	COG0589	response to stress
LGL85_10680	COG1285	pathogenesis
LGL85_10685	COG0840	transmembrane signaling receptor activity
LGL85_10705	COG1609	Transcriptional regulator
LGL85_10715	COG0604	alcohol dehydrogenase
LGL85_10715	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_10715	COG3321	synthase
LGL85_10735	COG3423	Transcriptional regulator
LGL85_10800	COG4382	Mu-like prophage protein Gp16
LGL85_10855	COG4383	Mu-like prophage protein gp29
LGL85_10885	COG4397	Mu-like prophage major head subunit gpT
LGL85_10910	COG4386	tail sheath protein
LGL85_10960	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL85_10980	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LGL85_11005	COG0582	viral genome integration into host DNA
LGL85_11020	COG3423	Transcriptional regulator
LGL85_11055	COG3451	type IV secretory pathway VirB4
LGL85_11075	COG3736	Type IV secretory pathway, component VirB8
LGL85_11090	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LGL85_11105	COG4227	nucleotidyltransferase activity
LGL85_11155	COG0471	metal ion transport
LGL85_11170	COG3051	citrate lyase alpha subunit
LGL85_11175	COG2301	Belongs to the HpcH HpaI aldolase family
LGL85_11180	COG3052	prosthetic group binding
LGL85_11185	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LGL85_11190	COG3290	protein histidine kinase activity
LGL85_11195	COG4565	transcriptional regulatory protein
LGL85_11210	COG2271	Major facilitator Superfamily
LGL85_11215	COG1840	ABC-type Fe3 transport system, periplasmic component
LGL85_11225	COG3842	ATPase activity
LGL85_11245	COG1289	transmembrane transporter activity
LGL85_11255	COG2925	Exonuclease
LGL85_11260	COG0531	amino acid
LGL85_11265	COG4771	TonB-dependent receptor
LGL85_11275	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL85_11285	COG0833	amino acid
LGL85_11290	COG0583	DNA-binding transcription factor activity
LGL85_11300	COG2855	membrane
LGL85_11305	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGL85_11310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL85_11310	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGL85_11310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL85_11315	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL85_11330	COG3005	denitrification pathway
LGL85_11335	COG0243	molybdopterin cofactor binding
LGL85_11350	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGL85_11360	COG0246	Mannitol dehydrogenase
LGL85_11370	COG0523	cobalamin synthesis protein
LGL85_11375	COG0671	phosphoesterase, PA-phosphatase related
LGL85_11380	COG0791	NLP P60 protein
LGL85_11385	COG2200	EAL domain
LGL85_11390	COG4166	transmembrane transport
LGL85_11395	COG4174	ABC transporter (Permease)
LGL85_11400	COG4239	(ABC) transporter, permease
LGL85_11405	COG4172	Belongs to the ABC transporter superfamily
LGL85_11415	COG2814	Major facilitator Superfamily
LGL85_11420	COG1187	pseudouridine synthase activity
LGL85_11425	COG1061	Type III restriction enzyme res subunit
LGL85_11440	COG3082	Protein of unknown function (DUF1414)
LGL85_11445	COG3083	sulfuric ester hydrolase activity
LGL85_11470	COG3778	Protein conserved in bacteria
LGL85_11475	COG3299	homolog of phage Mu protein gp47
LGL85_11520	COG4386	tail sheath protein
LGL85_11570	COG1802	Transcriptional regulator
LGL85_11570	COG4626	Terminase
LGL85_11625	COG1403	HNH endonuclease
LGL85_11650	COG4626	Terminase
LGL85_11650	COG1802	Transcriptional regulator
LGL85_11700	COG5532	Uncharacterized conserved protein (DUF2303)
LGL85_11705	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL85_11755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGL85_11760	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL85_11780	COG2223	nitrite transmembrane transporter activity
LGL85_11785	COG2198	Histidine kinase
LGL85_11785	COG0642	Histidine kinase
LGL85_11795	COG2205	protein histidine kinase activity
LGL85_11795	COG0784	Response regulator, receiver
LGL85_11805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL85_11810	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL85_11820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL85_11830	COG4574	serine-type endopeptidase inhibitor activity
LGL85_11840	COG2246	polysaccharide biosynthetic process
LGL85_11855	COG0814	amino acid
LGL85_11880	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGL85_11885	COG0596	Alpha beta hydrolase
LGL85_11890	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGL85_11895	COG1169	isochorismate synthase
LGL85_11900	COG4575	ribosome binding
LGL85_11915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_11920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGL85_11930	COG0839	Belongs to the complex I subunit 6 family
LGL85_11935	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_11940	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGL85_11945	COG1034	ATP synthesis coupled electron transport
LGL85_11965	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_11970	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL85_11975	COG0583	DNA-binding transcription factor activity
LGL85_11980	COG0436	Aminotransferase
LGL85_11985	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL85_11990	COG0490	domain, Protein
LGL85_11990	COG0471	metal ion transport
LGL85_12000	COG3013	Belongs to the UPF0304 family
LGL85_12005	COG3092	negative regulation of chromosome organization
LGL85_12015	COG0280	phosphate acetyltransferase
LGL85_12015	COG0857	belongs to the CobB CobQ family
LGL85_12020	COG1609	Transcriptional regulator
LGL85_12035	COG3037	sugar-specific permease SgaT UlaA
LGL85_12040	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LGL85_12045	COG0622	Phosphoesterase
LGL85_12060	COG0625	glutathione transferase activity
LGL85_12065	COG1090	epimerase
LGL85_12075	COG4160	amino acid transport
LGL85_12080	COG4215	(ABC) transporter
LGL85_12095	COG0163	prenyltransferase activity
LGL85_12100	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGL85_12105	COG1286	toxin biosynthetic process
LGL85_12110	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LGL85_12115	COG0285	dihydrofolate synthase activity
LGL85_12125	COG0586	Pfam SNARE associated Golgi protein
LGL85_12135	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL85_12160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL85_12165	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL85_12195	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL85_12210	COG3101	peptidyl-lysine hydroxylation
LGL85_12215	COG0730	response to heat
LGL85_12220	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LGL85_12230	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL85_12235	COG2840	Smr protein MutS2
LGL85_12240	COG2062	phosphohistidine phosphatase, SixA
LGL85_12245	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL85_12245	COG1024	Enoyl-CoA hydratase
LGL85_12250	COG0183	Belongs to the thiolase family
LGL85_12255	COG3691	Protein conserved in bacteria
LGL85_12270	COG4235	cytochrome complex assembly
LGL85_12270	COG3088	subunit of a heme lyase
LGL85_12275	COG4235	cytochrome complex assembly
LGL85_12275	COG3088	subunit of a heme lyase
LGL85_12280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL85_12285	COG1138	Cytochrome C-type biogenesis protein
LGL85_12290	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LGL85_12295	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL85_12300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL85_12305	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL85_12320	COG0582	viral genome integration into host DNA
LGL85_12330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LGL85_12385	COG2824	Alkylphosphonate utilization operon protein PhnA
LGL85_12390	COG2951	lytic endotransglycosylase activity
LGL85_12395	COG1598	PFAM Uncharacterised protein family UPF0150
LGL85_12405	COG3038	cytochrome b561
LGL85_12410	COG0436	Aminotransferase
LGL85_12420	COG3275	phosphorelay sensor kinase activity
LGL85_12425	COG3279	Response regulator of the LytR AlgR family
LGL85_12430	COG2223	nitrite transmembrane transporter activity
LGL85_12435	COG0837	glucose binding
LGL85_12455	COG1914	H( )-stimulated, divalent metal cation uptake system
LGL85_12460	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL85_12530	COG3530	Putative quorum-sensing-regulated virulence factor
LGL85_12535	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL85_12545	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LGL85_12555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL85_12570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL85_12580	COG4208	sulfate ABC transporter
LGL85_12585	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGL85_12590	COG4150	thiosulfate binding
LGL85_12600	COG1737	Transcriptional regulator
LGL85_12605	COG2731	YhcH YjgK YiaL family protein
LGL85_12620	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL85_12625	COG2837	iron assimilation
LGL85_12635	COG3111	PFAM Bacterial OB fold (BOF) protein
LGL85_12695	COG1671	Belongs to the UPF0178 family
LGL85_12700	COG0281	malic enzyme
LGL85_12700	COG0280	phosphate acetyltransferase
LGL85_12705	COG0494	nUDIX hydrolase
LGL85_12710	COG3005	denitrification pathway
LGL85_12715	COG3043	anaerobic respiration
LGL85_12720	COG0243	molybdopterin cofactor binding
LGL85_12725	COG3062	negative regulation of establishment of protein localization
LGL85_12730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL85_12730	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL85_12735	COG2197	response regulator
LGL85_12745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL85_12755	COG1605	Chorismate mutase
LGL85_12760	COG1393	Belongs to the ArsC family
LGL85_12765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGL85_12770	COG1876	peptidase activity
LGL85_12780	COG0400	carboxylic ester hydrolase activity
LGL85_12800	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LGL85_12805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL85_12810	COG2716	regulation of RNA biosynthetic process
LGL85_12815	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGL85_12820	COG0628	permease
LGL85_12825	COG4783	chaperone-mediated protein folding
LGL85_12830	COG1393	Belongs to the ArsC family
LGL85_12835	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGL85_12840	COG2233	PERMEase
LGL85_12845	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGL85_12850	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGL85_12855	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGL85_12860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL85_12870	COG0581	inorganic phosphate transmembrane transporter activity
LGL85_12875	COG0573	inorganic phosphate transmembrane transporter activity
LGL85_12880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGL85_12895	COG2239	Acts as a magnesium transporter
LGL85_12900	COG0443	Heat shock 70 kDa protein
LGL85_12910	COG3121	Chaperone
LGL85_12930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL85_12940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL85_12945	COG0477	Major facilitator Superfamily
LGL85_12950	COG2205	protein histidine kinase activity
LGL85_12955	COG0745	RESPONSE REGULATOR receiver
LGL85_12960	COG3422	double-strand break repair
LGL85_12965	COG0826	peptidase U32
LGL85_12970	COG1597	lipid kinase activity
LGL85_12985	COG0351	phosphomethylpyrimidine kinase
LGL85_13000	COG0519	Catalyzes the synthesis of GMP from XMP
LGL85_13000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGL85_13005	COG0516	GMP reductase activity
LGL85_13005	COG0517	IMP dehydrogenase activity
LGL85_13010	COG1570	exodeoxyribonuclease VII activity
LGL85_13015	COG1645	bacterial-type flagellum-dependent swarming motility
LGL85_13025	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL85_13030	COG2976	Protein conserved in bacteria
LGL85_13035	COG0124	histidyl-tRNA synthetase
LGL85_13055	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGL85_13070	COG4953	penicillin-binding protein 1C
LGL85_13075	COG2373	Large extracellular alpha-helical protein
LGL85_13090	COG2975	iron-sulfur cluster assembly
LGL85_13095	COG0633	Ferredoxin
LGL85_13100	COG0443	Heat shock 70 kDa protein
LGL85_13115	COG0822	iron-sulfur transferase activity
LGL85_13125	COG1959	2 iron, 2 sulfur cluster binding
LGL85_13130	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LGL85_13140	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL85_13145	COG3683	transport system, periplasmic component
LGL85_13150	COG3711	transcriptional antiterminator
LGL85_13155	COG2814	Major facilitator Superfamily
LGL85_13165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL85_13165	COG1017	nitric oxide dioxygenase activity
LGL85_13170	COG2188	Transcriptional regulator
LGL85_13180	COG3457	Alanine racemase
LGL85_13185	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LGL85_13200	COG0347	Belongs to the P(II) protein family
LGL85_13205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL85_13205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL85_13210	COG2204	response regulator
LGL85_13215	COG3170	Tfp pilus assembly protein FimV
LGL85_13220	COG2205	protein histidine kinase activity
LGL85_13235	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LGL85_13245	COG0560	Phosphoserine phosphatase
LGL85_13250	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_13250	COG1263	PTS System
LGL85_13260	COG1737	Transcriptional regulator
LGL85_13265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL85_13275	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGL85_13285	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGL85_13300	COG0481	GTPase activity
LGL85_13305	COG3086	response to oxidative stress
LGL85_13315	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LGL85_13325	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGL85_13335	COG0513	Belongs to the DEAD box helicase family
LGL85_13350	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LGL85_13360	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGL85_13365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGL85_13370	COG0497	DNA recombination
LGL85_13375	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL85_13385	COG2867	negative regulation of translational initiation
LGL85_13390	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGL85_13400	COG0582	viral genome integration into host DNA
LGL85_13435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL85_13530	COG3121	Chaperone
LGL85_13560	COG0583	DNA-binding transcription factor activity
LGL85_13635	COG1069	ribulokinase activity
LGL85_13645	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL85_13650	COG1129	ABC transporter
LGL85_13670	COG1620	l-lactate permease
LGL85_13675	COG1304	FMN binding
LGL85_13680	COG0579	oxidoreductase
LGL85_13685	COG1278	Cold shock
LGL85_13715	COG1780	Probably involved in ribonucleotide reductase function
LGL85_13720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL85_13730	COG4175	Glycine betaine
LGL85_13735	COG4176	ABC-type proline glycine betaine transport system permease component
LGL85_13740	COG2113	Glycine betaine
LGL85_13750	COG2814	Major facilitator Superfamily
LGL85_13755	COG1846	Transcriptional regulator
LGL85_13765	COG1566	PFAM secretion protein HlyD family protein
LGL85_13770	COG2814	Major facilitator Superfamily
LGL85_13775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL85_13780	COG3118	belongs to the thioredoxin family
LGL85_13785	COG3148	PFAM DTW domain containing protein
LGL85_13790	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL85_13790	COG1042	CoA-binding domain protein
LGL85_13790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL85_13795	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL85_13800	COG5544	Lipoprotein
LGL85_13825	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL85_13835	COG2011	ABC-type metal ion transport system permease component
LGL85_13840	COG1464	Belongs to the NlpA lipoprotein family
LGL85_13850	COG1720	tRNA m6t6A37 methyltransferase activity
LGL85_13855	COG0442	prolyl-tRNA aminoacylation
LGL85_13860	COG3015	lipoprotein NlpE involved in copper resistance
LGL85_13870	COG4681	YaeQ
LGL85_13880	COG4568	rho-dependent transcription termination
LGL85_13895	COG0346	lactoylglutathione lyase activity
LGL85_13910	COG0825	malonyl-CoA metabolic process
LGL85_13915	COG0587	DNA-directed DNA polymerase activity
LGL85_13920	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGL85_13940	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL85_13945	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LGL85_13955	COG0750	zinc metalloprotease
LGL85_13960	COG0575	Belongs to the CDS family
LGL85_13980	COG0528	UMP kinase activity
LGL85_13985	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGL85_14000	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LGL85_14005	COG2171	N-acyltransferase activity
LGL85_14020	COG0564	pseudouridine synthase activity
LGL85_14025	COG3098	single-species biofilm formation
LGL85_14040	COG1611	Belongs to the LOG family
LGL85_14050	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LGL85_14055	COG2363	Small membrane protein
LGL85_14060	COG0583	DNA-binding transcription factor activity
LGL85_14070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGL85_14075	COG2166	iron-sulfur cluster assembly
LGL85_14080	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGL85_14085	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LGL85_14105	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL85_14110	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL85_14110	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LGL85_14115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL85_14120	COG1074	ATP-dependent DNA helicase activity
LGL85_14125	COG1025	Belongs to the peptidase M16 family
LGL85_14130	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGL85_14135	COG4967	type IV pilus modification protein PilV
LGL85_14160	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGL85_14165	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LGL85_14175	COG3066	DNA modification
LGL85_14180	COG0861	Integral membrane protein TerC family
LGL85_14185	COG0667	Aldo Keto reductase
LGL85_14190	COG0477	Major facilitator Superfamily
LGL85_14195	COG0318	PFAM AMP-dependent synthetase and ligase
LGL85_14195	COG0204	Acyl-transferase
LGL85_14200	COG1609	Transcriptional regulator
LGL85_14210	COG0583	DNA-binding transcription factor activity
LGL85_14215	COG0583	DNA-binding transcription factor activity
LGL85_14265	COG4795	General secretion pathway protein
LGL85_14285	COG2165	general secretion pathway protein
LGL85_14300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL85_14330	COG1127	ABC transporter
LGL85_14335	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL85_14345	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGL85_14355	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGL85_14360	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL85_14365	COG4974	Belongs to the 'phage' integrase family
LGL85_14370	COG0716	FMN binding
LGL85_14380	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGL85_14390	COG1272	protein, Hemolysin III
LGL85_14410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGL85_14415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL85_14420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL85_14425	COG0006	proline dipeptidase activity
LGL85_14435	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGL85_14445	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGL85_14450	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL85_14455	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGL85_14470	COG1279	arginine transmembrane transporter activity
LGL85_14480	COG0191	fructose-bisphosphate aldolase activity
LGL85_14485	COG0126	phosphoglycerate kinase activity
LGL85_14490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGL85_14495	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGL85_14505	COG1166	arginine decarboxylase activity
LGL85_14510	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGL85_14525	COG0640	Transcriptional regulator
LGL85_14530	COG3091	SprT-like family
LGL85_14535	COG2356	endonuclease I
LGL85_14540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGL85_14545	COG0189	ligase activity
LGL85_14550	COG1678	Uncharacterized ACR, COG1678
LGL85_14555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGL85_14560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL85_14570	COG2805	Type II/IV secretion system protein
LGL85_14575	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGL85_14580	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGL85_14585	COG0762	integral membrane protein
LGL85_14590	COG1872	DUF167
LGL85_14595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGL85_14600	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL85_14615	COG3171	Protein conserved in bacteria
LGL85_14625	COG1194	a g-specific adenine glycosylase
LGL85_14630	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LGL85_14635	COG0741	lytic transglycosylase activity
LGL85_14670	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL85_14675	COG1882	Formate acetyltransferase
LGL85_14680	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGL85_14685	COG0814	amino acid
LGL85_14700	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_14705	COG1535	isochorismatase
LGL85_14705	COG3433	isochorismatase activity
LGL85_14710	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGL85_14715	COG1169	isochorismate synthase
LGL85_14720	COG4592	Periplasmic binding protein
LGL85_14730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL85_14735	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL85_14740	COG1120	ATPase activity
LGL85_14750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGL85_14755	COG3251	PFAM MbtH domain protein
LGL85_14765	COG4774	siderophore transport
LGL85_14770	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGL85_14795	COG4964	Belongs to the GSP D family
LGL85_14850	COG0848	biopolymer transport protein
LGL85_14855	COG0811	peptide transport
LGL85_14860	COG0626	cystathionine gamma-synthase activity
LGL85_14865	COG0586	Pfam SNARE associated Golgi protein
LGL85_14870	COG2207	Transcriptional regulator
LGL85_14875	COG1979	alcohol dehydrogenase
LGL85_14880	COG0656	L-ascorbic acid biosynthetic process
LGL85_14890	COG2132	Multicopper oxidase
LGL85_14905	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL85_14910	COG0583	DNA-binding transcription factor activity
LGL85_14915	COG0187	DNA topoisomerase II activity
LGL85_14920	COG3150	esterase
LGL85_14925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGL85_14930	COG3151	Protein conserved in bacteria
LGL85_14935	COG0494	nUDIX hydrolase
LGL85_14940	COG1538	Outer membrane efflux protein
LGL85_14945	COG5463	Belongs to the UPF0441 family
LGL85_14950	COG0754	glutathionylspermidine amidase activity
LGL85_14955	COG3384	dioxygenase
LGL85_14960	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGL85_14975	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LGL85_14975	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGL85_14985	COG3025	triphosphatase activity
LGL85_14990	COG4991	sh3 domain protein
LGL85_14995	COG0617	tRNA 3'-terminal CCA addition
LGL85_15000	COG1968	undecaprenyl-diphosphatase activity
LGL85_15005	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGL85_15010	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGL85_15015	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGL85_15020	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGL85_15025	COG0358	DNA primase activity
LGL85_15055	COG1028	Short-chain dehydrogenase reductase Sdr
LGL85_15090	COG0463	Glycosyl transferase, family 2
LGL85_15130	COG3210	domain, Protein
LGL85_15140	COG2831	hemolysin activation secretion protein
LGL85_15145	COG1902	pentaerythritol trinitrate reductase activity
LGL85_15145	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGL85_15160	COG1451	nucleotide metabolic process
LGL85_15165	COG0673	inositol 2-dehydrogenase activity
LGL85_15170	COG0861	Integral membrane protein TerC family
LGL85_15175	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LGL85_15185	COG2721	sulfolactate sulfo-lyase activity
LGL85_15200	COG2271	Major facilitator Superfamily
LGL85_15215	COG0586	Pfam SNARE associated Golgi protein
LGL85_15230	COG4575	ribosome binding
LGL85_15235	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LGL85_15245	COG2259	Doxx family
LGL85_15250	COG0583	DNA-binding transcription factor activity
LGL85_15255	COG1741	Belongs to the pirin family
LGL85_15270	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGL85_15285	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL85_15290	COG2823	Periplasmic or secreted lipoprotein
LGL85_15295	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL85_15300	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LGL85_15305	COG2198	Histidine kinase
LGL85_15305	COG0784	Response regulator, receiver
LGL85_15305	COG5002	protein histidine kinase activity
LGL85_15310	COG1242	4 iron, 4 sulfur cluster binding
LGL85_15315	COG0067	glutamate synthase
LGL85_15315	COG0070	glutamate synthase
LGL85_15315	COG0069	glutamate synthase activity
LGL85_15320	COG0493	'glutamate synthase
LGL85_15330	COG2969	positive regulation of protein catabolic process
LGL85_15335	COG0625	glutathione transferase activity
LGL85_15340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGL85_15345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGL85_15350	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGL85_15355	COG3105	Protein conserved in bacteria
LGL85_15360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL85_15370	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGL85_15375	COG5007	Belongs to the BolA IbaG family
LGL85_15380	COG3113	response to antibiotic
LGL85_15385	COG2854	intermembrane phospholipid transfer
LGL85_15390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL85_15395	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL85_15400	COG1127	ABC transporter
LGL85_15405	COG0530	calcium, potassium:sodium antiporter activity
LGL85_15410	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGL85_15410	COG0517	IMP dehydrogenase activity
LGL85_15415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGL85_15420	COG3117	lipopolysaccharide transmembrane transporter activity
LGL85_15425	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGL85_15430	COG1137	ATPase activity
LGL85_15435	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGL85_15455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL85_15460	COG0540	Belongs to the ATCase OTCase family
LGL85_15465	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LGL85_15475	COG0366	Alpha amylase catalytic
LGL85_15480	COG1263	PTS System
LGL85_15480	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL85_15490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGL85_15500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL85_15505	COG3783	Cytochrome b(562)
LGL85_15510	COG0312	modulator of DNA gyrase
LGL85_15515	COG3028	Belongs to the UPF0307 family
LGL85_15520	COG2732	(Barnase) inhibitor
LGL85_15525	COG4290	ribonuclease
LGL85_15535	COG1289	transmembrane transporter activity
LGL85_15540	COG1566	PFAM secretion protein HlyD family protein
LGL85_15550	COG0583	DNA-binding transcription factor activity
LGL85_15555	COG0312	modulator of DNA gyrase
LGL85_15560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL85_15565	COG3164	Protein of unknown function
LGL85_15575	COG0424	maF-like protein
LGL85_15580	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGL85_15585	COG1792	Involved in formation and maintenance of cell shape
LGL85_15590	COG1077	Cell shape determining protein MreB Mrl
LGL85_15595	COG2200	EAL domain
LGL85_15595	COG2199	diguanylate cyclase activity
LGL85_15600	COG0604	alcohol dehydrogenase
LGL85_15605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL85_15610	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LGL85_15620	COG0511	ligase activity, forming carbon-carbon bonds
LGL85_15625	COG0439	Biotin carboxylase
LGL85_15630	COG3924	membrane
LGL85_15635	COG4145	pantothenate transmembrane transporter activity
LGL85_15640	COG2264	protein methyltransferase activity
LGL85_15645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL85_15650	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGL85_15660	COG1560	Kdo2-lipid A biosynthetic process
LGL85_15670	COG1346	cytolysis
LGL85_15675	COG1380	Effector of murein hydrolase LrgA
LGL85_15680	COG0583	DNA-binding transcription factor activity
LGL85_15685	COG0025	NhaP-type Na H and K H
LGL85_15690	COG2252	PERMEase
LGL85_15705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGL85_15710	COG2315	Protein conserved in bacteria
LGL85_15715	COG1448	Aminotransferase
LGL85_15740	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL85_15745	COG0735	belongs to the Fur family
LGL85_15750	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGL85_15755	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGL85_15760	COG2937	Belongs to the GPAT DAPAT family
LGL85_15780	COG4580	involved in the transport of maltose and maltodextrins
LGL85_15795	COG2182	Extracellular solute-binding protein
LGL85_15800	COG1175	transmembrane transport
LGL85_15805	COG3833	ABC-type maltose transport systems, permease component
LGL85_15810	COG3223	Belongs to the PsiE family
LGL85_15820	COG0527	aspartate kinase activity
LGL85_15835	COG3328	transposase activity
LGL85_15865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LGL85_15950	COG0583	DNA-binding transcription factor activity
LGL85_15985	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGL85_16025	COG0138	bifunctional purine biosynthesis protein purh
LGL85_16030	COG0151	Belongs to the GarS family
LGL85_16050	COG1515	deoxyribonuclease V activity
LGL85_16055	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGL85_16060	COG2816	NAD+ diphosphatase activity
LGL85_16065	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LGL85_16080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL85_16085	COG2104	thiamine diphosphate biosynthetic process
LGL85_16090	COG2022	thiamine diphosphate biosynthetic process
LGL85_16100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGL85_16105	COG0085	RNA polymerase activity
LGL85_16110	COG0222	ribosome binding
LGL85_16115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGL85_16125	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGL85_16130	COG0250	Participates in transcription elongation, termination and antitermination
LGL85_16175	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGL85_16200	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LGL85_16205	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGL85_16210	COG1739	Uncharacterized protein family UPF0029
LGL85_16220	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL85_16220	COG1024	Enoyl-CoA hydratase
LGL85_16230	COG0543	2 iron, 2 sulfur cluster binding
LGL85_16245	COG0250	Participates in transcription elongation, termination and antitermination
LGL85_16260	COG0805	protein transport
LGL85_16265	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL85_16270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL85_16275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGL85_16280	COG3165	ubiquinone biosynthetic process from chorismate
LGL85_16285	COG2226	methyltransferase
LGL85_16290	COG1322	Protein conserved in bacteria
LGL85_16295	COG0586	Pfam SNARE associated Golgi protein
LGL85_16300	COG1966	Carbon starvation protein
LGL85_16315	COG0412	Dienelactone hydrolase
LGL85_16320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGL85_16325	COG0583	DNA-binding transcription factor activity
LGL85_16330	COG0697	spore germination
LGL85_16340	COG0584	glycerophosphoryl diester phosphodiesterase
LGL85_16350	COG0395	ABC-type sugar transport system, permease component
LGL85_16355	COG1175	transmembrane transport
LGL85_16360	COG1653	transport
LGL85_16395	COG0410	ABC transporter
LGL85_16405	COG4177	L-phenylalanine transmembrane transporter activity
LGL85_16425	COG1929	Belongs to the glycerate kinase type-1 family
LGL85_16430	COG2610	gluconate transmembrane transporter activity
LGL85_16435	COG3835	regulator
LGL85_16445	COG2177	Part of the ABC transporter FtsEX involved in
LGL85_16450	COG2884	Cell division ATP-binding protein ftsE
LGL85_16455	COG0552	protein localization to endoplasmic reticulum
LGL85_16455	COG0552	protein localization to endoplasmic reticulum
LGL85_16460	COG0742	ribosomal rna small subunit methyltransferase
LGL85_16465	COG3776	membrane
LGL85_16480	COG3714	YhhN family
LGL85_16495	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGL85_16505	COG0247	lactate metabolic process
LGL85_16515	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL85_16525	COG2271	Major facilitator Superfamily
LGL85_16530	COG0584	glycerophosphoryl diester phosphodiesterase
LGL85_16535	COG0561	phosphatase activity
LGL85_16540	COG2267	carboxylic ester hydrolase activity
LGL85_16545	COG1280	lysine exporter protein (LysE YggA)
LGL85_16550	COG0514	ATP-dependent DNA helicase (RecQ)
LGL85_16555	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LGL85_16560	COG2050	protein possibly involved in aromatic compounds catabolism
LGL85_16580	COG5564	TIM-barrel signal transduction protein
LGL85_16585	COG5441	Belongs to the UPF0261 family
LGL85_16595	COG0210	DNA helicase
LGL85_16600	COG1011	Hydrolase
LGL85_16605	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL85_16610	COG3159	Protein conserved in bacteria
LGL85_16615	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGL85_16620	COG5567	small periplasmic lipoprotein
LGL85_16630	COG3072	Adenylate cyclase
LGL85_16635	COG0181	hydroxymethylbilane synthase activity
LGL85_16640	COG1587	Uroporphyrinogen-III synthase
LGL85_16645	COG2959	enzyme of heme biosynthesis
LGL85_16650	COG3071	HemY protein
LGL85_16700	COG2244	polysaccharide biosynthetic process
LGL85_16705	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL85_16710	COG0456	acetyltransferase
LGL85_16715	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGL85_16720	COG1088	dTDP-glucose 4,6-dehydratase activity
LGL85_16725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGL85_16730	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL85_16735	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL85_16740	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGL85_16745	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGL85_16750	COG3118	belongs to the thioredoxin family
LGL85_16760	COG0248	Ppx GppA phosphatase
LGL85_16770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL85_16785	COG3397	chitin binding
LGL85_16795	COG0129	dihydroxy-acid dehydratase activity
LGL85_16805	COG3978	acetolactate synthase activity
LGL85_16825	COG3085	chromosome segregation
LGL85_16830	COG0583	DNA-binding transcription factor activity
LGL85_16905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL85_16915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL85_16915	COG0678	peroxiredoxin activity
LGL85_16920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL85_16955	COG1629	transport
LGL85_16960	COG0165	Argininosuccinate lyase
LGL85_16965	COG0137	argininosuccinate synthase activity
LGL85_16970	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL85_17015	COG0460	homoserine dehydrogenase
LGL85_17015	COG0527	aspartate kinase activity
LGL85_17020	COG0626	cystathionine gamma-synthase activity
LGL85_17025	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LGL85_17035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGL85_17040	COG1609	Transcriptional regulator
LGL85_17045	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL85_17050	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGL85_17055	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGL85_17060	COG1575	Belongs to the MenA family. Type 1 subfamily
LGL85_17065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGL85_17070	COG3074	FtsZ-dependent cytokinesis
LGL85_17075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGL85_17080	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGL85_17085	COG1494	fructose-1,6-bisphosphatase
LGL85_17090	COG2814	Major facilitator Superfamily
LGL85_17100	COG3152	Membrane
LGL85_17115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGL85_17125	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL85_17130	COG3678	ATP-independent chaperone mediated protein folding
LGL85_17135	COG0745	RESPONSE REGULATOR receiver
LGL85_17140	COG2205	protein histidine kinase activity
LGL85_17145	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGL85_17150	COG1045	serine acetyltransferase
LGL85_17155	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGL85_17160	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LGL85_17165	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL85_17170	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGL85_17175	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGL85_17180	COG4942	peptidase
LGL85_17185	COG2861	carbohydrate metabolic process
LGL85_17200	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL85_17205	COG0859	PFAM glycosyl transferase family 9
LGL85_17210	COG0859	PFAM glycosyl transferase family 9
LGL85_17215	COG1519	Transferase
LGL85_17235	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGL85_17240	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGL85_17245	COG2003	Belongs to the UPF0758 family
LGL85_17250	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGL85_17255	COG0756	dUTP diphosphatase activity
LGL85_17260	COG1309	transcriptional regulator
LGL85_17265	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGL85_17270	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGL85_17275	COG1561	YicC-like family, N-terminal region
LGL85_17290	COG5001	Diguanylate cyclase
LGL85_17295	COG1024	Enoyl-CoA hydratase
LGL85_17300	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL85_17315	COG2860	membrane
LGL85_17320	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL85_17330	COG1758	RNA polymerase activity
LGL85_17335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL85_17340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL85_17345	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGL85_17350	COG0786	glutamate:sodium symporter activity
LGL85_17355	COG2233	PERMEase
LGL85_17360	COG2982	Protein involved in outer membrane biogenesis
LGL85_17365	COG0456	acetyltransferase
LGL85_17380	COG1011	Hydrolase
LGL85_17395	COG3852	Histidine kinase
LGL85_17405	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL85_17415	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGL85_17420	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL85_17420	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL85_17425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL85_17430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGL85_17435	COG3084	Protein conserved in bacteria
LGL85_17445	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGL85_17470	COG2186	Transcriptional regulator
LGL85_17475	COG1609	Transcriptional regulator
LGL85_17480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL85_17490	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL85_17495	COG1129	ABC transporter
LGL85_17500	COG1869	D-ribose catabolic process
LGL85_17505	COG3158	transport of potassium into the cell
LGL85_17510	COG0714	Associated with various cellular activities
LGL85_17515	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LGL85_17525	COG2502	aspartate--ammonia ligase
LGL85_17530	COG1522	sequence-specific DNA binding
LGL85_17535	COG0716	FMN binding
LGL85_17540	COG0445	tRNA wobble uridine modification
LGL85_17545	COG0357	Ribosomal RNA small subunit methyltransferase G
LGL85_17550	COG3312	ion transport
LGL85_17555	COG0356	it plays a direct role in the translocation of protons across the membrane
LGL85_17565	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGL85_17575	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGL85_17580	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGL85_17590	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGL85_17605	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGL85_17610	COG0573	inorganic phosphate transmembrane transporter activity
LGL85_17615	COG0581	inorganic phosphate transmembrane transporter activity
LGL85_17625	COG0704	Plays a role in the regulation of phosphate uptake
LGL85_17630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL85_17635	COG0765	amino acid transport
LGL85_17640	COG0765	amino acid transport
LGL85_17645	COG2252	PERMEase
LGL85_17650	COG0840	transmembrane signaling receptor activity
LGL85_17660	COG3121	Chaperone
LGL85_17675	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGL85_17680	COG0706	membrane insertase activity
LGL85_17690	COG0594	ribonuclease P activity
LGL85_17695	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LGL85_17995	COG3093	addiction module antidote protein HigA
LGL85_18000	COG3549	Plasmid maintenance system killer
LGL85_18015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL85_18040	COG1122	ATPase activity
LGL85_18065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LGL85_18075	COG0431	NADPH-dependent FMN reductase
LGL85_18080	COG0640	Transcriptional regulator