locus-tag	class	description
LGL86_00010	COG0592	DNA-directed DNA polymerase activity
LGL86_00020	COG0187	DNA topoisomerase II activity
LGL86_00025	COG0561	phosphatase activity
LGL86_00030	COG0823	Involved in the tonB-independent uptake of proteins
LGL86_00035	COG5645	(Lipo)protein
LGL86_00050	COG0569	domain protein
LGL86_00050	COG2985	domain, Protein
LGL86_00055	COG3977	Valine--pyruvate aminotransferase
LGL86_00060	COG2885	chlorophyll binding
LGL86_00080	COG2818	Glycosylase
LGL86_00130	COG2213	PTS system mannitol-specific
LGL86_00130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL86_00140	COG3722	fumarate hydratase activity
LGL86_00150	COG2258	MOSC domain
LGL86_00155	COG0840	transmembrane signaling receptor activity
LGL86_00160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL86_00175	COG0437	4 iron, 4 sulfur cluster binding
LGL86_00180	COG2864	formate dehydrogenase
LGL86_00190	COG1921	L-seryl-tRNASec selenium transferase activity
LGL86_00195	COG3276	selenocysteine insertion sequence binding
LGL86_00200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LGL86_00210	COG3274	enterobacterial common antigen metabolic process
LGL86_00220	COG0582	viral genome integration into host DNA
LGL86_00255	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LGL86_00260	COG2986	histidine ammonia-lyase
LGL86_00280	COG2194	sulfuric ester hydrolase activity
LGL86_00285	COG2197	response regulator
LGL86_00290	COG3851	Histidine kinase
LGL86_00295	COG2271	Major facilitator Superfamily
LGL86_00305	COG0747	negative chemotaxis
LGL86_00310	COG0601	transmembrane transport
LGL86_00315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL86_00320	COG0444	Belongs to the ABC transporter superfamily
LGL86_00325	COG4608	Belongs to the ABC transporter superfamily
LGL86_00330	COG2194	sulfuric ester hydrolase activity
LGL86_00355	COG1215	transferase activity, transferring glycosyl groups
LGL86_00360	COG1215	transferase activity, transferring glycosyl groups
LGL86_00365	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
LGL86_00370	COG3118	belongs to the thioredoxin family
LGL86_00370	COG0457	Tetratricopeptide repeat
LGL86_00375	COG2199	diguanylate cyclase activity
LGL86_00375	COG2200	EAL domain
LGL86_00380	COG1301	dicarboxylic acid transport
LGL86_00385	COG0612	Peptidase, M16
LGL86_00390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL86_00395	COG1942	4-Oxalocrotonate Tautomerase
LGL86_00400	COG2200	EAL domain
LGL86_00405	COG2134	cdp-diacylglycerol pyrophosphatase
LGL86_00410	COG1295	ribonuclease BN
LGL86_00420	COG1301	dicarboxylic acid transport
LGL86_00425	COG0626	cystathionine gamma-synthase activity
LGL86_00440	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL86_00445	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LGL86_00450	COG0339	signal peptide processing
LGL86_00455	COG0742	ribosomal rna small subunit methyltransferase
LGL86_00465	COG0589	response to stress
LGL86_00475	COG0306	phosphate transporter
LGL86_00480	COG2081	HI0933 family
LGL86_00490	COG1247	-acetyltransferase
LGL86_00500	COG1741	Belongs to the pirin family
LGL86_00505	COG1609	Transcriptional regulator
LGL86_00510	COG2610	gluconate transmembrane transporter activity
LGL86_00515	COG3265	gluconokinase activity
LGL86_00520	COG2095	MarC family integral membrane protein
LGL86_00525	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL86_00530	COG3275	phosphorelay sensor kinase activity
LGL86_00535	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LGL86_00540	COG1523	belongs to the glycosyl hydrolase 13 family
LGL86_00545	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LGL86_00550	COG0297	glycogen (starch) synthase activity
LGL86_00555	COG0058	SHG alpha-glucan phosphorylase activity
LGL86_00560	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL86_00565	COG1349	DNA-binding transcription factor activity
LGL86_00570	COG0705	Rhomboid family
LGL86_00580	COG2909	trisaccharide binding
LGL86_00585	COG0058	SHG alpha-glucan phosphorylase activity
LGL86_00590	COG1640	4-alpha-glucanotransferase
LGL86_00600	COG1040	competence protein
LGL86_00605	COG0596	Alpha beta hydrolase
LGL86_00625	COG1918	ferrous iron import across plasma membrane
LGL86_00630	COG2183	response to ionizing radiation
LGL86_00655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL86_00670	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LGL86_00680	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LGL86_00685	COG1011	Hydrolase
LGL86_00695	COG0494	nUDIX hydrolase
LGL86_00700	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LGL86_00725	COG4796	Type ii and iii secretion system protein
LGL86_00730	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL86_00750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LGL86_00760	COG0180	Tryptophanyl-tRNA synthetase
LGL86_00780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LGL86_00785	COG0402	S-adenosylhomocysteine deaminase activity
LGL86_00790	COG0738	Major facilitator superfamily
LGL86_00805	COG1609	Transcriptional regulator
LGL86_00810	COG1486	melibiose metabolic process
LGL86_00815	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL86_00830	COG1289	transmembrane transporter activity
LGL86_00835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL86_00840	COG1765	OsmC-like protein
LGL86_00865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL86_00870	COG3954	Phosphoribulokinase
LGL86_00880	COG0429	hydrolase of the alpha beta-hydrolase fold
LGL86_00890	COG0859	PFAM glycosyl transferase family 9
LGL86_00895	COG1216	Glycosyl transferase, family 2
LGL86_00900	COG0488	(ABC) transporter
LGL86_00905	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL86_00915	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LGL86_00920	COG1047	Peptidyl-prolyl cis-trans
LGL86_00930	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL86_00935	COG2964	Protein conserved in bacteria
LGL86_00945	COG2923	Belongs to the DsrF TusC family
LGL86_00950	COG2168	tRNA wobble position uridine thiolation
LGL86_00955	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LGL86_00960	COG0049	tRNA binding
LGL86_00970	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LGL86_00985	COG0051	transcription antitermination factor activity, RNA binding
LGL86_00990	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LGL86_01000	COG0089	rRNA binding
LGL86_01005	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LGL86_01010	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LGL86_01015	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LGL86_01025	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LGL86_01030	COG0255	Belongs to the universal ribosomal protein uL29 family
LGL86_01035	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LGL86_01040	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LGL86_01050	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LGL86_01075	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LGL86_01080	COG1841	ribosomal large subunit assembly
LGL86_01085	COG0200	Binds to the 23S rRNA
LGL86_01090	COG0201	protein transport
LGL86_01095	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL86_01100	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LGL86_01110	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LGL86_01120	COG0203	ribosomal protein L17
LGL86_01125	COG0789	Transcriptional regulator
LGL86_01130	COG3036	rescue of stalled ribosome
LGL86_01135	COG1970	mechanosensitive ion channel activity
LGL86_01145	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LGL86_01145	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LGL86_01150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LGL86_01155	COG0242	peptide deformylase activity
LGL86_01160	COG0758	DNA mediated transformation
LGL86_01165	COG2922	Belongs to the Smg family
LGL86_01170	COG0551	DNA topoisomerase type I activity
LGL86_01175	COG0009	L-threonylcarbamoyladenylate synthase
LGL86_01185	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LGL86_01215	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL86_01220	COG3162	membrane
LGL86_01225	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LGL86_01230	COG1301	dicarboxylic acid transport
LGL86_01240	COG2391	methyltransferase activity
LGL86_01245	COG0425	Belongs to the sulfur carrier protein TusA family
LGL86_01250	COG1086	Polysaccharide biosynthesis protein
LGL86_01255	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL86_01260	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL86_01265	COG2089	acid synthase
LGL86_01285	COG1083	cytidylyl-transferase
LGL86_01285	COG2755	lipolytic protein G-D-S-L family
LGL86_01290	COG1028	Short-chain dehydrogenase reductase Sdr
LGL86_01310	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL86_01310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL86_01315	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LGL86_01335	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL86_01355	COG1309	transcriptional regulator
LGL86_01365	COG4232	protein-disulfide reductase activity
LGL86_01375	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL86_01405	COG1509	lysine 2,3-aminomutase activity
LGL86_01415	COG3397	chitin binding
LGL86_01435	COG3188	usher protein
LGL86_01455	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL86_01460	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LGL86_01465	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL86_01470	COG1053	succinate dehydrogenase
LGL86_01475	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LGL86_01480	COG3264	Mechanosensitive ion channel
LGL86_01480	COG1511	domain protein
LGL86_01485	COG0688	phosphatidylethanolamine metabolic process
LGL86_01490	COG1162	GTPase activity
LGL86_01495	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LGL86_01515	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LGL86_01520	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LGL86_01520	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LGL86_01525	COG0802	atpase or kinase
LGL86_01530	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL86_01540	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LGL86_01550	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LGL86_01555	COG0330	HflC and HflK could
LGL86_01560	COG0330	HflC and HflK could
LGL86_01565	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LGL86_01570	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LGL86_01575	COG1959	2 iron, 2 sulfur cluster binding
LGL86_01580	COG0557	exoribonuclease II activity
LGL86_01585	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL86_01605	COG3121	Chaperone
LGL86_01610	COG3188	usher protein
LGL86_01630	COG1073	alpha beta
LGL86_01640	COG0360	Binds together with S18 to 16S ribosomal RNA
LGL86_01645	COG2965	DNA replication, synthesis of RNA primer
LGL86_01650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LGL86_01655	COG0359	binds to the 23S rRNA
LGL86_01660	COG3061	Opacity-associated protein A
LGL86_01665	COG0545	Peptidyl-prolyl cis-trans isomerase
LGL86_01675	COG0737	Belongs to the 5'-nucleotidase family
LGL86_01680	COG1218	3'(2'),5'-bisphosphate nucleotidase
LGL86_01685	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LGL86_01695	COG1253	flavin adenine dinucleotide binding
LGL86_01700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL86_01705	COG0729	surface antigen
LGL86_01710	COG2911	Protein conserved in bacteria
LGL86_01715	COG2105	PFAM AIG2 family protein
LGL86_01720	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LGL86_01730	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL86_01745	COG3423	Transcriptional regulator
LGL86_01760	COG0142	geranyltranstransferase activity
LGL86_01780	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LGL86_01785	COG0642	Histidine kinase
LGL86_01790	COG0745	RESPONSE REGULATOR receiver
LGL86_01795	COG2027	D-alanyl-D-alanine carboxypeptidase
LGL86_01805	COG1534	Rna-binding protein
LGL86_01810	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LGL86_01820	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LGL86_01825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LGL86_01830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LGL86_01850	COG0195	Participates in both transcription termination and antitermination
LGL86_01860	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LGL86_01875	COG1185	polyribonucleotide nucleotidyltransferase activity
LGL86_01890	COG0513	Belongs to the DEAD box helicase family
LGL86_01895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LGL86_01910	COG0826	peptidase U32
LGL86_01915	COG0826	peptidase U32
LGL86_01920	COG3154	lipid carrier protein
LGL86_01925	COG3153	acetyltransferase
LGL86_01930	COG2827	Endonuclease containing a URI domain
LGL86_01935	COG0531	amino acid
LGL86_01940	COG1982	Orn Lys Arg decarboxylase major
LGL86_01950	COG3787	Belongs to the UPF0306 family
LGL86_01955	COG0702	epimerase
LGL86_01960	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LGL86_01965	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
LGL86_01970	COG3454	Phosphonate metabolism
LGL86_01975	COG4778	phosphonate C-P lyase system protein PhnL
LGL86_01980	COG4107	phosphonate C-P lyase system protein PhnK
LGL86_01985	COG3627	carbon phosphorus lyase activity
LGL86_01990	COG3626	phosphonate metabolism
LGL86_01995	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
LGL86_02000	COG3624	Phosphonate C-P lyase system protein PhnG
LGL86_02020	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LGL86_02035	COG2927	DNA polymerase III (CHI subunit)
LGL86_02040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LGL86_02045	COG0795	lipopolysaccharide-transporting ATPase activity
LGL86_02050	COG0795	lipopolysaccharide-transporting ATPase activity
LGL86_02090	COG5492	domain, Protein
LGL86_02110	COG3119	arylsulfatase activity
LGL86_02115	COG1349	DNA-binding transcription factor activity
LGL86_02125	COG2222	sugar isomerase
LGL86_02130	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL86_02135	COG3715	PTS system
LGL86_02140	COG3716	PTS system mannose fructose sorbose family IID component
LGL86_02150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL86_02160	COG1028	Short-chain dehydrogenase reductase Sdr
LGL86_02170	COG0641	radical SAM
LGL86_02175	COG3119	arylsulfatase activity
LGL86_02200	COG0859	PFAM glycosyl transferase family 9
LGL86_02215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL86_02220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL86_02230	COG2376	Dihydroxyacetone kinase
LGL86_02235	COG1461	Dihydroxyacetone kinase
LGL86_02240	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LGL86_02240	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL86_02240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL86_02280	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
LGL86_02295	COG2823	Periplasmic or secreted lipoprotein
LGL86_02305	COG4667	esterase of the alpha-beta hydrolase superfamily
LGL86_02310	COG0084	hydrolase, TatD family'
LGL86_02315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL86_02330	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LGL86_02340	COG3726	membrane protein affecting hemolysin expression
LGL86_02345	COG0560	Phosphoserine phosphatase
LGL86_02360	COG0488	(ABC) transporter
LGL86_02385	COG0741	lytic transglycosylase activity
LGL86_02390	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
LGL86_02395	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
LGL86_02400	COG0406	alpha-ribazole phosphatase activity
LGL86_02405	COG2207	Transcriptional regulator
LGL86_02405	COG3708	Transcriptional regulator
LGL86_02410	COG3045	CreA protein
LGL86_02415	COG0745	RESPONSE REGULATOR receiver
LGL86_02450	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL86_02455	COG0521	Mo-molybdopterin cofactor biosynthetic process
LGL86_02460	COG0477	Major facilitator Superfamily
LGL86_02470	COG1584	GPR1 FUN34 yaaH family protein
LGL86_02475	COG0443	Heat shock 70 kDa protein
LGL86_02485	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL86_02490	COG0583	DNA-binding transcription factor activity
LGL86_02500	COG0196	riboflavin kinase activity
LGL86_02510	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LGL86_02515	COG1047	Peptidyl-prolyl cis-trans
LGL86_02520	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LGL86_02535	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LGL86_02545	COG2966	Psort location CytoplasmicMembrane, score
LGL86_02570	COG2967	ApaG domain
LGL86_02575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LGL86_02580	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LGL86_02590	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LGL86_02600	COG0564	pseudouridine synthase activity
LGL86_02605	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LGL86_02610	COG0417	DNA replication proofreading
LGL86_02615	COG0586	Pfam SNARE associated Golgi protein
LGL86_02625	COG1178	ABC-type Fe3 transport system permease component
LGL86_02630	COG4143	(ABC) transporter
LGL86_02645	COG2814	Major facilitator Superfamily
LGL86_02655	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LGL86_02660	COG0473	3-isopropylmalate dehydrogenase activity
LGL86_02675	COG1022	Amp-dependent synthetase and ligase
LGL86_02680	COG0028	Belongs to the TPP enzyme family
LGL86_02705	COG0275	rRNA processing
LGL86_02710	COG3116	cell division
LGL86_02715	COG0768	penicillin binding
LGL86_02720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LGL86_02725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LGL86_02740	COG0772	Belongs to the SEDS family
LGL86_02745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LGL86_02750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LGL86_02760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LGL86_02765	COG0849	cell division
LGL86_02770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LGL86_02795	COG0494	nUDIX hydrolase
LGL86_02815	COG0516	GMP reductase activity
LGL86_02820	COG1459	type II secretion system
LGL86_02825	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL86_02830	COG4969	Belongs to the N-Me-Phe pilin family
LGL86_02845	COG3725	Membrane protein required for beta-lactamase induction
LGL86_02850	COG1113	amino acid transport
LGL86_02855	COG2186	Transcriptional regulator
LGL86_02860	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LGL86_02865	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL86_02870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL86_02880	COG1049	propionate catabolic process, 2-methylcitrate cycle
LGL86_02885	COG3112	Uncharacterised protein family (UPF0231)
LGL86_02900	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LGL86_02910	COG2132	Multicopper oxidase
LGL86_02920	COG0288	reversible hydration of carbon dioxide
LGL86_02925	COG1131	(ABC) transporter
LGL86_02930	COG0842	Transport permease protein
LGL86_02935	COG0726	polysaccharide deacetylase
LGL86_02940	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LGL86_02945	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LGL86_02950	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LGL86_02955	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LGL86_02960	COG0617	tRNA 3'-terminal CCA addition
LGL86_02975	COG1489	DNA binding
LGL86_02980	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
LGL86_02985	COG1643	Atp-dependent helicase
LGL86_02990	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL86_02995	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LGL86_03005	COG0316	Belongs to the HesB IscA family
LGL86_03010	COG2860	membrane
LGL86_03020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL86_03025	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LGL86_03030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL86_03040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LGL86_03045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL86_03050	COG3956	TIGRFAM MazG family protein
LGL86_03055	COG0504	CTP synthase activity
LGL86_03065	COG0602	queuosine metabolic process
LGL86_03070	COG0720	synthase
LGL86_03075	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LGL86_03085	COG0175	sulfate reduction
LGL86_03100	COG2234	aminopeptidase activity
LGL86_03105	COG1648	precorrin-2 dehydrogenase activity
LGL86_03105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LGL86_03110	COG0175	sulfate reduction
LGL86_03115	COG2895	sulfate adenylyltransferase (ATP) activity
LGL86_03120	COG0529	Catalyzes the synthesis of activated sulfate
LGL86_03130	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LGL86_03140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LGL86_03145	COG0585	pseudouridine synthase activity
LGL86_03150	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LGL86_03160	COG4942	peptidase
LGL86_03160	COG1388	LysM domain
LGL86_03165	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LGL86_03170	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LGL86_03245	COG2205	protein histidine kinase activity
LGL86_03275	COG0741	lytic transglycosylase activity
LGL86_03405	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL86_03425	COG3397	chitin binding
LGL86_03435	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
LGL86_03480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL86_03490	COG3031	protein transport across the cell outer membrane
LGL86_03515	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL86_03515	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LGL86_03530	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LGL86_03535	COG2137	regulation of response to DNA damage stimulus
LGL86_03540	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LGL86_03545	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LGL86_03585	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL86_03590	COG1238	metal cluster binding
LGL86_03595	COG2918	glutathione biosynthetic process
LGL86_03600	COG1854	S-ribosylhomocysteine lyase activity
LGL86_03605	COG4536	flavin adenine dinucleotide binding
LGL86_03610	COG4137	Cytochrome C assembly protein
LGL86_03615	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LGL86_03625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LGL86_03630	COG0336	Belongs to the RNA methyltransferase TrmD family
LGL86_03635	COG0335	large ribosomal subunit rRNA binding
LGL86_03640	COG3137	Salt-induced outer membrane protein
LGL86_03645	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LGL86_03650	COG3279	Response regulator of the LytR AlgR family
LGL86_03655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL86_03660	COG1605	Chorismate mutase
LGL86_03660	COG0287	Prephenate dehydrogenase
LGL86_03665	COG1605	Chorismate mutase
LGL86_03665	COG0077	Prephenate dehydratase
LGL86_03675	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LGL86_03680	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL86_03685	COG0564	pseudouridine synthase activity
LGL86_03690	COG1496	oxidoreductase activity
LGL86_03695	COG0542	response to heat
LGL86_03730	COG3021	interspecies interaction between organisms
LGL86_03735	COG1388	LysM domain
LGL86_03735	COG0741	lytic transglycosylase activity
LGL86_03745	COG2226	methyltransferase
LGL86_03755	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL86_03765	COG1960	acyl-CoA dehydrogenase activity
LGL86_03770	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL86_03775	COG0121	glutamine amidotransferase
LGL86_03780	COG3034	peptidoglycan biosynthetic process
LGL86_03790	COG1805	sodium ion transport
LGL86_03795	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL86_03800	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL86_03805	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LGL86_03815	COG1477	protein flavinylation
LGL86_03820	COG2991	Protein conserved in bacteria
LGL86_03830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LGL86_03835	COG2195	Cleaves the N-terminal amino acid of tripeptides
LGL86_03840	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LGL86_03845	COG1073	alpha beta
LGL86_03860	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LGL86_03895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LGL86_03915	COG4126	flavin adenine dinucleotide binding
LGL86_03925	COG2974	May be involved in recombination
LGL86_03930	COG1940	carbohydrate kinase activity
LGL86_03935	COG0419	ATPase involved in DNA repair
LGL86_03940	COG0420	3'-5' exonuclease activity
LGL86_03945	COG0745	RESPONSE REGULATOR receiver
LGL86_03950	COG5002	protein histidine kinase activity
LGL86_03965	COG1113	amino acid transport
LGL86_03970	COG0366	Alpha amylase catalytic
LGL86_03975	COG0300	oxidoreductase activity
LGL86_03980	COG0450	alkyl hydroperoxide reductase
LGL86_03985	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LGL86_04000	COG1862	Preprotein translocase
LGL86_04005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL86_04010	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LGL86_04015	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LGL86_04020	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL86_04020	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LGL86_04025	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LGL86_04035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LGL86_04040	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LGL86_04045	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LGL86_04050	COG0142	geranyltranstransferase activity
LGL86_04085	COG0693	protein deglycase activity
LGL86_04090	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LGL86_04095	COG1666	GTP binding
LGL86_04100	COG2814	Major facilitator Superfamily
LGL86_04110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LGL86_04115	COG1845	cytochrome c oxidase, subunit III
LGL86_04120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LGL86_04125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LGL86_04135	COG2223	nitrite transmembrane transporter activity
LGL86_04140	COG3056	Lipoprotein
LGL86_04145	COG0271	Belongs to the BolA IbaG family
LGL86_04155	COG0740	serine-type endopeptidase activity
LGL86_04160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LGL86_04165	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LGL86_04170	COG0776	regulation of translation
LGL86_04175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL86_04180	COG1555	photosystem II stabilization
LGL86_04185	COG0824	Thioesterase
LGL86_04190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LGL86_04195	COG4533	DNA binding
LGL86_04210	COG1522	sequence-specific DNA binding
LGL86_04215	COG1132	(ABC) transporter
LGL86_04220	COG1132	(ABC) transporter
LGL86_04225	COG0347	Belongs to the P(II) protein family
LGL86_04230	COG0004	ammonium transporteR
LGL86_04235	COG1946	Acyl-CoA thioesterase
LGL86_04240	COG3695	enzyme binding
LGL86_04265	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LGL86_04270	COG0254	rRNA binding
LGL86_04275	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL86_04280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL86_04285	COG1309	transcriptional regulator
LGL86_04290	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LGL86_04295	COG3264	Mechanosensitive ion channel
LGL86_04295	COG1196	nuclear chromosome segregation
LGL86_04310	COG2832	Protein of unknown function (DUF454)
LGL86_04315	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LGL86_04355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LGL86_04360	COG0326	Molecular chaperone. Has ATPase activity
LGL86_04375	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL86_04380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL86_04385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL86_04385	COG4651	solute:proton antiporter activity
LGL86_04390	COG0737	Belongs to the 5'-nucleotidase family
LGL86_04395	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LGL86_04400	COG3735	TraB family
LGL86_04405	COG2217	Heavy metal translocating P-type atpase
LGL86_04410	COG0789	Transcriptional regulator
LGL86_04415	COG1585	Membrane protein implicated in regulation of membrane protease activity
LGL86_04420	COG0330	HflC and HflK could
LGL86_04425	COG3118	belongs to the thioredoxin family
LGL86_04430	COG0300	oxidoreductase activity
LGL86_04435	COG2755	lipolytic protein G-D-S-L family
LGL86_04440	COG4181	ATPase activity
LGL86_04445	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LGL86_04450	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LGL86_04455	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LGL86_04460	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL86_04465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LGL86_04495	COG3188	usher protein
LGL86_04500	COG3121	Chaperone
LGL86_04530	COG2501	S4 domain
LGL86_04535	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LGL86_04550	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LGL86_04555	COG1393	Belongs to the ArsC family
LGL86_04565	COG1022	Amp-dependent synthetase and ligase
LGL86_04590	COG3038	cytochrome b561
LGL86_04620	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LGL86_04630	COG1215	transferase activity, transferring glycosyl groups
LGL86_04650	COG3250	beta-galactosidase activity
LGL86_04665	COG1309	transcriptional regulator
LGL86_04695	COG2197	response regulator
LGL86_04700	COG1278	Cold shock
LGL86_04720	COG3706	GGDEF domain
LGL86_04730	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LGL86_04740	COG2921	Belongs to the UPF0250 family
LGL86_04745	COG1686	Belongs to the peptidase S11 family
LGL86_04750	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL86_04755	COG0772	Belongs to the SEDS family
LGL86_04760	COG0768	penicillin binding
LGL86_04765	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LGL86_04770	COG0799	negative regulation of ribosome biogenesis
LGL86_04775	COG0582	viral genome integration into host DNA
LGL86_04895	COG0305	Participates in initiation and elongation during chromosome replication
LGL86_04945	COG3646	Phage regulatory protein
LGL86_04970	COG3567	Phage-associated protein, HI1409 family
LGL86_04975	COG2369	cell adhesion
LGL86_05105	COG5301	cellulose 1,4-beta-cellobiosidase activity
LGL86_05115	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LGL86_05120	COG1466	dna polymerase III delta subunit
LGL86_05125	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
LGL86_05135	COG2888	peptidyl-tyrosine sulfation
LGL86_05140	COG1126	abc transporter atp-binding protein
LGL86_05145	COG0765	amino acid transport
LGL86_05150	COG0765	amino acid transport
LGL86_05160	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LGL86_05165	COG4535	Mg2 and Co2 transporter CorC
LGL86_05170	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LGL86_05175	COG1702	phosphate starvation-inducible protein PhoH
LGL86_05180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LGL86_05185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL86_05220	COG0367	asparagine synthase
LGL86_05225	COG0647	UMP catabolic process
LGL86_05230	COG1846	Transcriptional regulator
LGL86_05230	COG1940	carbohydrate kinase activity
LGL86_05235	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LGL86_05245	COG1263	PTS System
LGL86_05245	COG2190	(PTS) system
LGL86_05245	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL86_05270	COG0735	belongs to the Fur family
LGL86_05280	COG0840	transmembrane signaling receptor activity
LGL86_05290	COG0596	Alpha beta hydrolase
LGL86_05295	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LGL86_05300	COG0033	Phosphoglucomutase
LGL86_05310	COG0745	RESPONSE REGULATOR receiver
LGL86_05315	COG2205	protein histidine kinase activity
LGL86_05320	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LGL86_05325	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LGL86_05345	COG3272	Protein of unknown function (DUF1722)
LGL86_05350	COG0415	Belongs to the DNA photolyase family
LGL86_05355	COG5212	phosphodiesterase
LGL86_05360	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LGL86_05365	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
LGL86_05370	COG1984	allophanate hydrolase subunit 2
LGL86_05375	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
LGL86_05410	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LGL86_05415	COG1053	succinate dehydrogenase
LGL86_05420	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LGL86_05425	COG0567	Dehydrogenase, E1 component
LGL86_05430	COG0508	dehydrogenase complex catalyzes the overall conversion of
LGL86_05435	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL86_05440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LGL86_05445	COG0737	Belongs to the 5'-nucleotidase family
LGL86_05450	COG1271	oxidase subunit
LGL86_05455	COG1294	oxidase, subunit
LGL86_05460	COG4890	Cyd operon protein YbgT
LGL86_05465	COG3790	cyd operon protein YbgE
LGL86_05470	COG0824	Thioesterase
LGL86_05475	COG0811	peptide transport
LGL86_05480	COG0848	biopolymer transport protein
LGL86_05485	COG3064	Membrane
LGL86_05485	COG3064	Membrane
LGL86_05490	COG0823	Involved in the tonB-independent uptake of proteins
LGL86_05495	COG2885	chlorophyll binding
LGL86_05500	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LGL86_05540	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LGL86_05550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL86_05550	COG2205	protein histidine kinase activity
LGL86_05560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL86_05565	COG0588	phosphoglycerate mutase activity
LGL86_05575	COG2017	converts alpha-aldose to the beta-anomer
LGL86_05585	COG1085	galactose-1-phosphate uridylyltransferase
LGL86_05590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LGL86_05605	COG2005	Transcriptional regulator
LGL86_05605	COG3585	molybdate ion transport
LGL86_05615	COG0725	ABC transporter, periplasmic molybdate-binding protein
LGL86_05620	COG4149	molybdate abc transporter
LGL86_05630	COG0561	phosphatase activity
LGL86_05635	COG2706	6-phosphogluconolactonase activity
LGL86_05650	COG0156	8-amino-7-oxononanoate synthase activity
LGL86_05655	COG2226	methyltransferase
LGL86_05670	COG0556	nucleotide-excision repair
LGL86_05675	COG4628	conserved protein (DUF2132)
LGL86_05690	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL86_05695	COG1120	ATPase activity
LGL86_05700	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LGL86_05705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LGL86_05715	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LGL86_05720	COG0314	molybdopterin synthase activity
LGL86_05725	COG0670	Belongs to the BI1 family
LGL86_05730	COG0842	Transport permease protein
LGL86_05735	COG0842	Transport permease protein
LGL86_05740	COG1131	(ABC) transporter
LGL86_05745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL86_05750	COG1309	transcriptional regulator
LGL86_05755	COG0513	Belongs to the DEAD box helicase family
LGL86_05760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL86_05770	COG1686	Belongs to the peptidase S11 family
LGL86_05775	COG0277	FAD linked oxidase domain protein
LGL86_05795	COG2261	transglycosylase associated protein
LGL86_05805	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LGL86_05815	COG3639	organic phosphonate transmembrane transporter activity
LGL86_05820	COG4807	Protein conserved in bacteria
LGL86_05825	COG2897	thiosulfate sulfurtransferase activity
LGL86_05830	COG1732	Glycine betaine
LGL86_05835	COG1174	glycine betaine transport
LGL86_05840	COG1125	glycine betaine transport
LGL86_05845	COG1174	glycine betaine transport
LGL86_05850	COG0531	amino acid
LGL86_05855	COG1982	Orn Lys Arg decarboxylase major
LGL86_05865	COG0697	spore germination
LGL86_05880	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LGL86_05885	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LGL86_05890	COG1126	abc transporter atp-binding protein
LGL86_05895	COG0765	amino acid transport
LGL86_05900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL86_05920	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LGL86_05925	COG2239	Acts as a magnesium transporter
LGL86_05930	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL86_05935	COG0488	(ABC) transporter
LGL86_05940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL86_05945	COG0303	'Molybdopterin
LGL86_05965	COG0583	DNA-binding transcription factor activity
LGL86_05970	COG0477	Major facilitator Superfamily
LGL86_05975	COG0302	gtp cyclohydrolase
LGL86_05980	COG2311	Membrane
LGL86_06005	COG2949	membrane
LGL86_06010	COG0281	malic enzyme
LGL86_06020	COG0583	DNA-binding transcription factor activity
LGL86_06030	COG1346	cytolysis
LGL86_06035	COG1380	Effector of murein hydrolase LrgA
LGL86_06045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL86_06045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LGL86_06050	COG0489	protein tyrosine kinase activity
LGL86_06055	COG0572	uridine kinase
LGL86_06060	COG0717	Belongs to the dCTP deaminase family
LGL86_06065	COG2982	Protein involved in outer membrane biogenesis
LGL86_06070	COG3069	C4-dicarboxylate transmembrane transporter activity
LGL86_06075	COG1253	flavin adenine dinucleotide binding
LGL86_06080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL86_06085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LGL86_06090	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LGL86_06100	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LGL86_06100	COG0140	phosphoribosyl-ATP diphosphatase activity
LGL86_06110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LGL86_06120	COG0131	Imidazoleglycerol-phosphate dehydratase
LGL86_06120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL86_06125	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LGL86_06130	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LGL86_06145	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL86_06150	COG0625	glutathione transferase activity
LGL86_06165	COG0626	cystathionine gamma-synthase activity
LGL86_06175	COG1686	Belongs to the peptidase S11 family
LGL86_06180	COG1760	l-serine dehydratase
LGL86_06185	COG0814	amino acid
LGL86_06190	COG1349	DNA-binding transcription factor activity
LGL86_06200	COG0671	phosphoesterase, PA-phosphatase related
LGL86_06210	COG2985	domain, Protein
LGL86_06210	COG0569	domain protein
LGL86_06230	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LGL86_06235	COG3842	ATPase activity
LGL86_06240	COG1176	ABC-type spermidine putrescine transport system, permease component I
LGL86_06245	COG1177	transmembrane transport
LGL86_06260	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL86_06265	COG4160	amino acid transport
LGL86_06270	COG4215	(ABC) transporter
LGL86_06275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL86_06280	COG1126	abc transporter atp-binding protein
LGL86_06290	COG0393	Putative heavy-metal-binding
LGL86_06295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL86_06300	COG0702	epimerase
LGL86_06305	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
LGL86_06310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL86_06315	COG1151	hydroxylamine reductase activity
LGL86_06320	COG2431	L-lysine efflux transmembrane transporter activity
LGL86_06325	COG3593	DNA synthesis involved in DNA repair
LGL86_06330	COG2990	Protein conserved in bacteria
LGL86_06335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL86_06345	COG1278	Cold shock
LGL86_06350	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LGL86_06355	COG0542	response to heat
LGL86_06360	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LGL86_06370	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LGL86_06380	COG0492	ferredoxin-NADP+ reductase activity
LGL86_06385	COG1522	sequence-specific DNA binding
LGL86_06390	COG3107	peptidoglycan biosynthetic process
LGL86_06390	COG1674	ftsk spoiiie
LGL86_06395	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LGL86_06400	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LGL86_06405	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LGL86_06410	COG2814	Major facilitator Superfamily
LGL86_06415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LGL86_06420	COG1882	Formate acetyltransferase
LGL86_06425	COG2116	formate transmembrane transporter activity
LGL86_06430	COG1944	ATP diphosphatase activity
LGL86_06435	COG0252	asparaginase activity
LGL86_06445	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LGL86_06455	COG0539	negative regulation of cytoplasmic translation
LGL86_06465	COG2333	competence protein COMEC
LGL86_06465	COG0658	competence protein
LGL86_06475	COG1663	tetraacyldisaccharide 4'-kinase activity
LGL86_06480	COG5383	Protein conserved in bacteria
LGL86_06490	COG1278	Cold shock
LGL86_06495	COG2835	tetraacyldisaccharide 4'-kinase activity
LGL86_06500	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LGL86_06505	COG3173	Aminoglycoside phosphotransferase
LGL86_06510	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LGL86_06515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL86_06520	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
LGL86_06530	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LGL86_06535	COG2989	Protein conserved in bacteria
LGL86_06540	COG3108	Peptidase M15
LGL86_06545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LGL86_06550	COG1448	Aminotransferase
LGL86_06565	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LGL86_06570	COG0308	aminopeptidase N
LGL86_06575	COG0167	dihydroorotate dehydrogenase activity
LGL86_06585	COG0633	Ferredoxin
LGL86_06585	COG3217	Mosc domain protein beta barrel domain protein
LGL86_06590	COG0116	Belongs to the methyltransferase superfamily
LGL86_06590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL86_06595	COG0488	(ABC) transporter
LGL86_06600	COG2995	paraquat-inducible protein a
LGL86_06605	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL86_06605	COG3008	intermembrane lipid transfer
LGL86_06610	COG3009	Protein conserved in bacteria
LGL86_06615	COG3130	regulation of translation
LGL86_06620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LGL86_06625	COG1067	ATP-dependent peptidase activity
LGL86_06630	COG3120	sequence-specific DNA binding
LGL86_06640	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
LGL86_06645	COG3070	regulator of competence-specific genes
LGL86_06650	COG1289	transmembrane transporter activity
LGL86_06655	COG3304	Inner membrane component domain
LGL86_06660	COG0210	DNA helicase
LGL86_06665	COG1803	Methylglyoxal synthase
LGL86_06675	COG1832	CoA-binding protein
LGL86_06680	COG3785	DNA binding
LGL86_06685	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LGL86_06690	COG1254	Belongs to the acylphosphatase family
LGL86_06695	COG2920	part of a sulfur-relay system
LGL86_06705	COG0288	reversible hydration of carbon dioxide
LGL86_06725	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LGL86_06730	COG2943	transferase activity, transferring hexosyl groups
LGL86_06745	COG0675	Transposase, IS605 OrfB family
LGL86_06760	COG1560	Kdo2-lipid A biosynthetic process
LGL86_06770	COG0628	permease
LGL86_06795	COG0418	dihydroorotase activity
LGL86_06800	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LGL86_06810	COG1530	ribonuclease E activity
LGL86_06815	COG0564	pseudouridine synthase activity
LGL86_06820	COG0424	maF-like protein
LGL86_06825	COG1399	metal-binding, possibly nucleic acid-binding protein
LGL86_06830	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LGL86_06840	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LGL86_06845	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LGL86_06855	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LGL86_06860	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL86_06865	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LGL86_06870	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LGL86_06875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LGL86_06880	COG0470	DNA polymerase III
LGL86_06885	COG0084	hydrolase, TatD family'
LGL86_06890	COG1263	PTS System
LGL86_06890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL86_06895	COG0537	adenosine 5'-monophosphoramidase activity
LGL86_06900	COG5633	Lipoprotein
LGL86_06905	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LGL86_06920	COG3150	esterase
LGL86_06925	COG1252	NADH dehydrogenase
LGL86_06930	COG3134	Outer membrane lipoprotein
LGL86_06935	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LGL86_06940	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL86_06950	COG4591	ABC-type transport system involved in lipoprotein release permease component
LGL86_06970	COG2850	peptidyl-arginine hydroxylation
LGL86_06975	COG2205	protein histidine kinase activity
LGL86_06980	COG0745	RESPONSE REGULATOR receiver
LGL86_06990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LGL86_06995	COG2915	High frequency lysogenization protein hflD homolog
LGL86_07000	COG0482	sulfurtransferase activity
LGL86_07010	COG1187	pseudouridine synthase activity
LGL86_07015	COG0538	isocitrate dehydrogenase activity
LGL86_07020	COG0582	viral genome integration into host DNA
LGL86_07060	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL86_07065	COG5532	Uncharacterized conserved protein (DUF2303)
LGL86_07115	COG1802	Transcriptional regulator
LGL86_07115	COG4626	Terminase
LGL86_07140	COG1403	HNH endonuclease
LGL86_07175	COG3179	chitinase
LGL86_07185	COG3646	Phage regulatory protein
LGL86_07200	COG4626	Terminase
LGL86_07200	COG1802	Transcriptional regulator
LGL86_07280	COG1674	ftsk spoiiie
LGL86_07280	COG1178	ABC-type Fe3 transport system permease component
LGL86_07325	COG2771	luxR family
LGL86_07330	COG3916	Acyl-homoserine-lactone synthase
LGL86_07335	COG2723	6-phospho-beta-galactosidase activity
LGL86_07345	COG0339	signal peptide processing
LGL86_07350	COG0840	transmembrane signaling receptor activity
LGL86_07375	COG0675	Transposase, IS605 OrfB family
LGL86_07385	COG4565	transcriptional regulatory protein
LGL86_07390	COG3290	protein histidine kinase activity
LGL86_07395	COG0471	metal ion transport
LGL86_07440	COG4977	sequence-specific DNA binding
LGL86_07445	COG1702	phosphate starvation-inducible protein PhoH
LGL86_07450	COG0387	Pfam Sodium calcium exchanger
LGL86_07455	COG2375	cellular response to nickel ion
LGL86_07460	COG3850	Histidine kinase
LGL86_07470	COG1294	oxidase, subunit
LGL86_07475	COG1271	oxidase subunit
LGL86_07480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL86_07485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LGL86_07490	COG3138	arginine N-succinyltransferase
LGL86_07500	COG3724	N-succinylarginine dihydrolase activity
LGL86_07520	COG1228	amidohydrolase
LGL86_07530	COG0402	S-adenosylhomocysteine deaminase activity
LGL86_07550	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL86_07555	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LGL86_07560	COG3383	formate dehydrogenase (NAD+) activity
LGL86_07565	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL86_07570	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LGL86_07580	COG3260	NADH ubiquinone oxidoreductase 20
LGL86_07585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL86_07590	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LGL86_07590	COG3261	NADH dehydrogenase
LGL86_07595	COG0650	Formate hydrogenlyase subunit 4
LGL86_07600	COG0651	ATP synthesis coupled electron transport
LGL86_07605	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL86_07615	COG0375	protein maturation
LGL86_07620	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LGL86_07625	COG0298	carbon dioxide binding
LGL86_07630	COG0409	Hydrogenase expression formation protein
LGL86_07635	COG0309	Hydrogenase expression formation protein (HypE)
LGL86_07670	COG2207	Transcriptional regulator
LGL86_07670	COG3708	Transcriptional regulator
LGL86_07675	COG0012	GTP binding
LGL86_07685	COG0193	aminoacyl-tRNA hydrolase activity
LGL86_07695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LGL86_07705	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LGL86_07710	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LGL86_07715	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LGL86_07720	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL86_07735	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LGL86_07740	COG0659	secondary active sulfate transmembrane transporter activity
LGL86_07745	COG3706	GGDEF domain
LGL86_07770	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL86_07780	COG3381	protein complex oligomerization
LGL86_07800	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL86_07810	COG0673	inositol 2-dehydrogenase activity
LGL86_07815	COG0728	peptidoglycan biosynthetic process
LGL86_07840	COG3102	Protein conserved in bacteria
LGL86_07845	COG3142	Participates in the control of copper homeostasis
LGL86_07860	COG3788	relative of glutathione S-transferase, MAPEG superfamily
LGL86_07865	COG1801	Protein of unknown function DUF72
LGL86_07875	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LGL86_07880	COG0494	nUDIX hydrolase
LGL86_07890	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LGL86_07900	COG2255	four-way junction helicase activity
LGL86_07905	COG3104	oligopeptide transport
LGL86_07910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL86_07915	COG1121	(ABC) transporter
LGL86_07920	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LGL86_07925	COG0739	heme binding
LGL86_07930	COG1560	Kdo2-lipid A biosynthetic process
LGL86_07935	COG0469	pyruvate kinase activity
LGL86_07940	COG1737	Transcriptional regulator
LGL86_07945	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LGL86_07950	COG0800	Aldolase
LGL86_07960	COG2076	Multidrug Resistance protein
LGL86_07965	COG0251	oxidation-reduction process
LGL86_07970	COG1199	ATP-dependent helicase activity
LGL86_07975	COG1214	PFAM Peptidase M22, glycoprotease
LGL86_07980	COG3065	identical protein binding
LGL86_07985	COG0318	PFAM AMP-dependent synthetase and ligase
LGL86_07990	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LGL86_07995	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LGL86_08000	COG2894	cell division
LGL86_08005	COG0850	regulation of cytokinetic process
LGL86_08010	COG3100	YcgL domain-containing protein
LGL86_08015	COG0179	Fumarylacetoacetate (FAA) hydrolase
LGL86_08020	COG2983	Belongs to the UPF0260 family
LGL86_08040	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LGL86_08050	COG2719	SpoVR family
LGL86_08055	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LGL86_08060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LGL86_08065	COG2814	Major facilitator Superfamily
LGL86_08075	COG2202	Pas domain
LGL86_08075	COG2199	diguanylate cyclase activity
LGL86_08075	COG2200	EAL domain
LGL86_08095	COG2718	Belongs to the UPF0229 family
LGL86_08100	COG2766	serine protein kinase
LGL86_08105	COG3713	MltA-interacting MipA family protein
LGL86_08110	COG2194	sulfuric ester hydrolase activity
LGL86_08125	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LGL86_08130	COG3139	Protein of unknown function (DUF1315)
LGL86_08135	COG1335	isochorismatase
LGL86_08140	COG0252	asparaginase activity
LGL86_08145	COG0616	signal peptide processing
LGL86_08150	COG0778	Nitroreductase
LGL86_08160	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LGL86_08170	COG0494	nUDIX hydrolase
LGL86_08175	COG0708	Exodeoxyribonuclease III
LGL86_08205	COG0788	formyltetrahydrofolate deformylase activity
LGL86_08215	COG1752	Esterase of the alpha-beta hydrolase superfamily
LGL86_08220	COG0745	RESPONSE REGULATOR receiver
LGL86_08240	COG1454	alcohol dehydrogenase
LGL86_08240	COG1012	belongs to the aldehyde dehydrogenase family
LGL86_08245	COG2095	MarC family integral membrane protein
LGL86_08250	COG4166	transmembrane transport
LGL86_08265	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LGL86_08280	COG3099	Belongs to the UPF0263 family
LGL86_08285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL86_08305	COG2350	Protein conserved in bacteria
LGL86_08320	COG3710	Transcriptional regulator
LGL86_08355	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LGL86_08380	COG0727	PFAM Uncharacterised protein family (UPF0153)
LGL86_08385	COG3047	cAMP biosynthetic process
LGL86_08400	COG0133	tryptophan synthase activity
LGL86_08405	COG0135	phosphoribosylanthranilate isomerase activity
LGL86_08405	COG0134	indole-3-glycerol-phosphate synthase activity
LGL86_08415	COG0512	Glutamine amidotransferase of anthranilate synthase
LGL86_08425	COG0613	PHP domain protein
LGL86_08430	COG0009	L-threonylcarbamoyladenylate synthase
LGL86_08445	COG1187	pseudouridine synthase activity
LGL86_08455	COG1028	Short-chain dehydrogenase reductase Sdr
LGL86_08460	COG0616	signal peptide processing
LGL86_08475	COG0583	DNA-binding transcription factor activity
LGL86_08490	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LGL86_08500	COG0671	phosphoesterase, PA-phosphatase related
LGL86_08505	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
LGL86_08510	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LGL86_08530	COG0023	Translation Initiation Factor
LGL86_08540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LGL86_08545	COG3447	MASE1 domain protein
LGL86_08545	COG5001	Diguanylate cyclase
LGL86_08545	COG5002	protein histidine kinase activity
LGL86_08550	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LGL86_08555	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LGL86_08565	COG4659	FMN binding
LGL86_08575	COG2207	Transcriptional regulator
LGL86_08575	COG3708	Transcriptional regulator
LGL86_08590	COG4657	Part of a membrane complex involved in electron transport
LGL86_08600	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LGL86_08610	COG0673	inositol 2-dehydrogenase activity
LGL86_08615	COG0385	Bile acid
LGL86_08620	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LGL86_08625	COG5339	Protein conserved in bacteria
LGL86_08630	COG1482	cell wall glycoprotein biosynthetic process
LGL86_08635	COG0114	fumarate hydratase activity
LGL86_08645	COG1940	carbohydrate kinase activity
LGL86_08650	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LGL86_08670	COG1742	UPF0060 membrane protein
LGL86_08675	COG4221	oxidoreductase activity
LGL86_08680	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL86_08700	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LGL86_08740	COG1011	Hydrolase
LGL86_08750	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LGL86_08755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LGL86_08760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LGL86_08765	COG0589	response to stress
LGL86_08795	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
LGL86_08800	COG3623	hexulose-6-phosphate isomerase
LGL86_08805	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LGL86_08810	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LGL86_08820	COG0531	amino acid
LGL86_08830	COG0745	RESPONSE REGULATOR receiver
LGL86_08835	COG2205	protein histidine kinase activity
LGL86_08850	COG2207	Transcriptional regulator
LGL86_08855	COG1881	PFAM PEBP family protein
LGL86_08865	COG3591	Belongs to the peptidase S1B family
LGL86_08870	COG1643	Atp-dependent helicase
LGL86_08875	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LGL86_08880	COG3784	Protein of unknown function (DUF1318)
LGL86_08895	COG2911	Protein conserved in bacteria
LGL86_08900	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LGL86_08905	COG3187	Heat shock protein
LGL86_08910	COG3042	response to heat
LGL86_08915	COG1285	pathogenesis
LGL86_08925	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL86_08925	COG0674	pyruvate-flavodoxin oxidoreductase activity
LGL86_08925	COG1013	pyruvate-flavodoxin oxidoreductase activity
LGL86_08925	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LGL86_08940	COG4166	transmembrane transport
LGL86_08945	COG2866	Carboxypeptidase
LGL86_08950	COG4948	Mandelate Racemase Muconate Lactonizing
LGL86_08955	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LGL86_08965	COG5642	Protein of unknown function (DUF2384)
LGL86_08970	COG5654	RES domain protein
LGL86_08975	COG3768	UPF0283 membrane protein
LGL86_08980	COG3106	COG3106 Predicted ATPase
LGL86_08990	COG1983	PspC domain protein
LGL86_09000	COG1842	Phage shock protein A
LGL86_09005	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LGL86_09020	COG4166	transmembrane transport
LGL86_09030	COG4171	peptide transport system, permease
LGL86_09035	COG4172	Belongs to the ABC transporter superfamily
LGL86_09040	COG4172	Belongs to the ABC transporter superfamily
LGL86_09050	COG3104	oligopeptide transport
LGL86_09060	COG0484	heat shock protein binding
LGL86_09105	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LGL86_09110	COG3133	Outer membrane lipoprotein
LGL86_09115	COG1846	Transcriptional regulator
LGL86_09125	COG4989	oxidoreductase activity
LGL86_09130	COG3313	Fe-S protein
LGL86_09135	COG2194	sulfuric ester hydrolase activity
LGL86_09140	COG1309	transcriptional regulator
LGL86_09145	COG1902	pentaerythritol trinitrate reductase activity
LGL86_09160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LGL86_09165	COG0791	NLP P60 protein
LGL86_09170	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LGL86_09180	COG1609	Transcriptional regulator
LGL86_09185	COG0583	DNA-binding transcription factor activity
LGL86_09190	COG2814	Major facilitator Superfamily
LGL86_09195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LGL86_09200	COG0307	riboflavin synthase, alpha
LGL86_09235	COG1376	ErfK ybiS ycfS ynhG family protein
LGL86_09235	COG1388	LysM domain
LGL86_09240	COG2166	iron-sulfur cluster assembly
LGL86_09250	COG0719	Fe-S assembly protein
LGL86_09255	COG0396	ATPase activity
LGL86_09260	COG0719	Fe-S assembly protein
LGL86_09265	COG0316	Belongs to the HesB IscA family
LGL86_09270	COG2050	protein possibly involved in aromatic compounds catabolism
LGL86_09275	COG0247	lactate metabolic process
LGL86_09275	COG0277	FAD linked oxidase domain protein
LGL86_09280	COG0628	permease
LGL86_09290	COG0574	Belongs to the PEP-utilizing enzyme family
LGL86_09290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LGL86_09295	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LGL86_09300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LGL86_09310	COG4771	TonB-dependent receptor
LGL86_09315	COG3720	iron ion transport
LGL86_09320	COG4558	Periplasmic binding protein
LGL86_09325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL86_09330	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LGL86_09340	COG0095	Lipoate-protein ligase
LGL86_09345	COG0791	NLP P60 protein
LGL86_09350	COG2076	Multidrug Resistance protein
LGL86_09355	COG2076	Multidrug Resistance protein
LGL86_09360	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LGL86_09375	COG0463	Glycosyl transferase, family 2
LGL86_09380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL86_09390	COG4139	cobalamin transport
LGL86_09435	COG2184	nucleotidyltransferase activity
LGL86_09450	COG2314	TM2 domain
LGL86_09455	COG0776	regulation of translation
LGL86_09530	COG0803	Belongs to the bacterial solute-binding protein 9 family
LGL86_09535	COG1121	(ABC) transporter
LGL86_09540	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL86_09545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LGL86_09550	COG3001	Fructosamine kinase
LGL86_09560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LGL86_09565	COG1988	membrane-bound metal-dependent
LGL86_09570	COG1823	symporter activity
LGL86_09575	COG3023	N-Acetylmuramoyl-L-alanine amidase
LGL86_09585	COG2814	Major facilitator Superfamily
LGL86_09595	COG0501	Belongs to the peptidase M48B family
LGL86_09600	COG0793	Belongs to the peptidase S41A family
LGL86_09610	COG1956	GAF domain-containing protein
LGL86_09615	COG2995	paraquat-inducible protein a
LGL86_09620	COG3008	intermembrane lipid transfer
LGL86_09625	COG3706	GGDEF domain
LGL86_09625	COG5001	Diguanylate cyclase
LGL86_09625	COG4251	negative regulation of phosphorylation
LGL86_09625	COG2203	Gaf domain
LGL86_09705	COG1276	copper resistance
LGL86_09710	COG2372	response to copper ion
LGL86_09715	COG1528	Iron-storage protein
LGL86_09730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LGL86_09735	COG1770	oligopeptidase
LGL86_09745	COG3097	Belongs to the UPF0267 family
LGL86_09750	COG3141	response to X-ray
LGL86_09755	COG0513	Belongs to the DEAD box helicase family
LGL86_09775	COG0494	nUDIX hydrolase
LGL86_09780	COG1760	l-serine dehydratase
LGL86_09785	COG1253	flavin adenine dinucleotide binding
LGL86_09790	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL86_09790	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL86_09795	COG3715	PTS system
LGL86_09800	COG3716	PTS system mannose fructose sorbose family IID component
LGL86_09805	COG4811	Protein of unknown function (DUF986)
LGL86_09810	COG1971	Probably functions as a manganese efflux pump
LGL86_09830	COG1960	acyl-CoA dehydrogenase activity
LGL86_09840	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LGL86_09870	COG2226	methyltransferase
LGL86_09875	COG0768	penicillin binding
LGL86_09880	COG1496	oxidoreductase activity
LGL86_09900	COG1113	amino acid transport
LGL86_09935	COG2207	Transcriptional regulator
LGL86_09955	COG1132	(ABC) transporter
LGL86_09965	COG2203	Gaf domain
LGL86_09965	COG3706	GGDEF domain
LGL86_09965	COG4251	negative regulation of phosphorylation
LGL86_09965	COG5001	Diguanylate cyclase
LGL86_09985	COG1181	Belongs to the D-alanine--D-alanine ligase family
LGL86_10005	COG1278	Cold shock
LGL86_10010	COG1278	Cold shock
LGL86_10015	COG1278	Cold shock
LGL86_10030	COG1917	Cupin 2, conserved barrel domain protein
LGL86_10030	COG2169	Transcriptional regulator
LGL86_10035	COG1447	Phosphotransferase system cellobiose-specific component IIA
LGL86_10040	COG2723	6-phospho-beta-galactosidase activity
LGL86_10045	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL86_10050	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
LGL86_10055	COG1187	pseudouridine synthase activity
LGL86_10065	COG3122	Protein conserved in bacteria
LGL86_10070	COG1757	Na H antiporter
LGL86_10085	COG2235	arginine
LGL86_10100	COG0076	glutamate decarboxylase activity
LGL86_10105	COG0531	amino acid
LGL86_10140	COG2153	protein acetylation
LGL86_10145	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LGL86_10175	COG0840	transmembrane signaling receptor activity
LGL86_10180	COG2801	Transposase and inactivated derivatives
LGL86_10205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LGL86_10210	COG0322	excinuclease ABC activity
LGL86_10215	COG2197	response regulator
LGL86_10240	COG1113	amino acid transport
LGL86_10250	COG0531	amino acid
LGL86_10255	COG3710	Transcriptional regulator
LGL86_10260	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LGL86_10265	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL86_10265	COG0506	proline dehydrogenase activity
LGL86_10265	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LGL86_10270	COG1126	abc transporter atp-binding protein
LGL86_10275	COG0765	amino acid transport
LGL86_10280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL86_10285	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LGL86_10295	COG1191	sigma factor activity
LGL86_10335	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LGL86_10340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LGL86_10355	COG1677	Flagellar hook-basal body complex protein FliE
LGL86_10365	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LGL86_10370	COG1317	bacterial-type flagellum organization
LGL86_10375	COG1157	protein secretion by the type III secretion system
LGL86_10390	COG1580	Controls the rotational direction of flagella during chemotaxis
LGL86_10470	COG1558	bacterial-type flagellum-dependent cell motility
LGL86_10475	COG1815	bacterial-type flagellum-dependent cell motility
LGL86_10485	COG2747	anti-sigma28 factor FlgM
LGL86_10490	COG3418	PFAM FlgN family protein
LGL86_10500	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL86_10505	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LGL86_10510	COG1404	Belongs to the peptidase S8 family
LGL86_10510	COG4935	Belongs to the peptidase S8 family
LGL86_10515	COG2197	response regulator
LGL86_10530	COG3188	usher protein
LGL86_10535	COG3121	Chaperone
LGL86_10545	COG3539	Fimbrial protein
LGL86_10575	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LGL86_10580	COG0745	RESPONSE REGULATOR receiver
LGL86_10590	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LGL86_10595	COG0840	transmembrane signaling receptor activity
LGL86_10600	COG0840	transmembrane signaling receptor activity
LGL86_10605	COG0835	chemotaxis
LGL86_10610	COG2198	Histidine kinase
LGL86_10610	COG0643	Histidine kinase
LGL86_10615	COG1360	Flagellar Motor Protein
LGL86_10635	COG0589	response to stress
LGL86_10640	COG1285	pathogenesis
LGL86_10645	COG0840	transmembrane signaling receptor activity
LGL86_10665	COG1609	Transcriptional regulator
LGL86_10675	COG0604	alcohol dehydrogenase
LGL86_10675	COG3321	synthase
LGL86_10675	COG1028	Short-chain dehydrogenase reductase Sdr
LGL86_10710	COG0582	viral genome integration into host DNA
LGL86_10725	COG3423	Transcriptional regulator
LGL86_10760	COG3451	type IV secretory pathway VirB4
LGL86_10780	COG3736	Type IV secretory pathway, component VirB8
LGL86_10795	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LGL86_10810	COG4227	nucleotidyltransferase activity
LGL86_10860	COG0471	metal ion transport
LGL86_10875	COG3051	citrate lyase alpha subunit
LGL86_10880	COG2301	Belongs to the HpcH HpaI aldolase family
LGL86_10885	COG3052	prosthetic group binding
LGL86_10890	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
LGL86_10895	COG3290	protein histidine kinase activity
LGL86_10900	COG4565	transcriptional regulatory protein
LGL86_10915	COG2271	Major facilitator Superfamily
LGL86_10920	COG1840	ABC-type Fe3 transport system, periplasmic component
LGL86_10930	COG3842	ATPase activity
LGL86_10950	COG1289	transmembrane transporter activity
LGL86_10960	COG2925	Exonuclease
LGL86_10965	COG0531	amino acid
LGL86_10970	COG4771	TonB-dependent receptor
LGL86_10980	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL86_10990	COG0833	amino acid
LGL86_10995	COG0583	DNA-binding transcription factor activity
LGL86_11005	COG2855	membrane
LGL86_11010	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LGL86_11015	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LGL86_11015	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL86_11015	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LGL86_11020	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL86_11035	COG3005	denitrification pathway
LGL86_11040	COG0243	molybdopterin cofactor binding
LGL86_11055	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LGL86_11065	COG0246	Mannitol dehydrogenase
LGL86_11075	COG0523	cobalamin synthesis protein
LGL86_11080	COG0671	phosphoesterase, PA-phosphatase related
LGL86_11085	COG0791	NLP P60 protein
LGL86_11090	COG2200	EAL domain
LGL86_11095	COG4166	transmembrane transport
LGL86_11100	COG4174	ABC transporter (Permease)
LGL86_11105	COG4239	(ABC) transporter, permease
LGL86_11110	COG4172	Belongs to the ABC transporter superfamily
LGL86_11120	COG2814	Major facilitator Superfamily
LGL86_11125	COG1187	pseudouridine synthase activity
LGL86_11130	COG1061	Type III restriction enzyme res subunit
LGL86_11145	COG3082	Protein of unknown function (DUF1414)
LGL86_11150	COG3083	sulfuric ester hydrolase activity
LGL86_11175	COG3778	Protein conserved in bacteria
LGL86_11180	COG3299	homolog of phage Mu protein gp47
LGL86_11225	COG4386	tail sheath protein
LGL86_11275	COG1802	Transcriptional regulator
LGL86_11275	COG4626	Terminase
LGL86_11330	COG1403	HNH endonuclease
LGL86_11355	COG4626	Terminase
LGL86_11355	COG1802	Transcriptional regulator
LGL86_11405	COG5532	Uncharacterized conserved protein (DUF2303)
LGL86_11410	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL86_11460	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LGL86_11465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL86_11485	COG2223	nitrite transmembrane transporter activity
LGL86_11490	COG0642	Histidine kinase
LGL86_11490	COG2198	Histidine kinase
LGL86_11500	COG0784	Response regulator, receiver
LGL86_11500	COG2205	protein histidine kinase activity
LGL86_11510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LGL86_11515	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL86_11525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL86_11535	COG4574	serine-type endopeptidase inhibitor activity
LGL86_11545	COG2246	polysaccharide biosynthetic process
LGL86_11560	COG0814	amino acid
LGL86_11585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LGL86_11590	COG0596	Alpha beta hydrolase
LGL86_11595	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LGL86_11600	COG1169	isochorismate synthase
LGL86_11605	COG4575	ribosome binding
LGL86_11620	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL86_11625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LGL86_11635	COG0839	Belongs to the complex I subunit 6 family
LGL86_11640	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL86_11645	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LGL86_11650	COG1034	ATP synthesis coupled electron transport
LGL86_11670	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL86_11675	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LGL86_11680	COG0583	DNA-binding transcription factor activity
LGL86_11685	COG0436	Aminotransferase
LGL86_11690	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LGL86_11695	COG0490	domain, Protein
LGL86_11695	COG0471	metal ion transport
LGL86_11705	COG3013	Belongs to the UPF0304 family
LGL86_11710	COG3092	negative regulation of chromosome organization
LGL86_11720	COG0857	belongs to the CobB CobQ family
LGL86_11720	COG0280	phosphate acetyltransferase
LGL86_11725	COG1609	Transcriptional regulator
LGL86_11740	COG3037	sugar-specific permease SgaT UlaA
LGL86_11745	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LGL86_11750	COG0622	Phosphoesterase
LGL86_11765	COG0625	glutathione transferase activity
LGL86_11770	COG1090	epimerase
LGL86_11780	COG4160	amino acid transport
LGL86_11785	COG4215	(ABC) transporter
LGL86_11800	COG0163	prenyltransferase activity
LGL86_11805	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LGL86_11810	COG1286	toxin biosynthetic process
LGL86_11815	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LGL86_11820	COG0285	dihydrofolate synthase activity
LGL86_11830	COG0586	Pfam SNARE associated Golgi protein
LGL86_11840	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LGL86_11865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LGL86_11870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL86_11900	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LGL86_11915	COG3101	peptidyl-lysine hydroxylation
LGL86_11920	COG0730	response to heat
LGL86_11925	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
LGL86_11935	COG2890	protein-(glutamine-N5) methyltransferase activity
LGL86_11940	COG2840	Smr protein MutS2
LGL86_11945	COG2062	phosphohistidine phosphatase, SixA
LGL86_11950	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL86_11950	COG1024	Enoyl-CoA hydratase
LGL86_11955	COG0183	Belongs to the thiolase family
LGL86_11960	COG3691	Protein conserved in bacteria
LGL86_11975	COG4235	cytochrome complex assembly
LGL86_11975	COG3088	subunit of a heme lyase
LGL86_11980	COG4235	cytochrome complex assembly
LGL86_11980	COG3088	subunit of a heme lyase
LGL86_11985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LGL86_11990	COG1138	Cytochrome C-type biogenesis protein
LGL86_11995	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LGL86_12000	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL86_12005	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL86_12010	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LGL86_12025	COG0582	viral genome integration into host DNA
LGL86_12030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LGL86_12085	COG2824	Alkylphosphonate utilization operon protein PhnA
LGL86_12090	COG2951	lytic endotransglycosylase activity
LGL86_12095	COG1598	PFAM Uncharacterised protein family UPF0150
LGL86_12105	COG3038	cytochrome b561
LGL86_12110	COG0436	Aminotransferase
LGL86_12120	COG3275	phosphorelay sensor kinase activity
LGL86_12125	COG3279	Response regulator of the LytR AlgR family
LGL86_12130	COG2223	nitrite transmembrane transporter activity
LGL86_12135	COG0837	glucose binding
LGL86_12155	COG1914	H( )-stimulated, divalent metal cation uptake system
LGL86_12160	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL86_12235	COG3530	Putative quorum-sensing-regulated virulence factor
LGL86_12240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL86_12250	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
LGL86_12260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL86_12275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LGL86_12285	COG4208	sulfate ABC transporter
LGL86_12290	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LGL86_12295	COG4150	thiosulfate binding
LGL86_12305	COG1737	Transcriptional regulator
LGL86_12310	COG2731	YhcH YjgK YiaL family protein
LGL86_12325	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL86_12330	COG2837	iron assimilation
LGL86_12340	COG3111	PFAM Bacterial OB fold (BOF) protein
LGL86_12395	COG1671	Belongs to the UPF0178 family
LGL86_12400	COG0281	malic enzyme
LGL86_12400	COG0280	phosphate acetyltransferase
LGL86_12405	COG0494	nUDIX hydrolase
LGL86_12410	COG3005	denitrification pathway
LGL86_12415	COG3043	anaerobic respiration
LGL86_12420	COG0243	molybdopterin cofactor binding
LGL86_12425	COG3062	negative regulation of establishment of protein localization
LGL86_12430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL86_12430	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL86_12435	COG2197	response regulator
LGL86_12445	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL86_12455	COG1605	Chorismate mutase
LGL86_12460	COG1393	Belongs to the ArsC family
LGL86_12465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LGL86_12470	COG1876	peptidase activity
LGL86_12480	COG0400	carboxylic ester hydrolase activity
LGL86_12500	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LGL86_12505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LGL86_12510	COG2716	regulation of RNA biosynthetic process
LGL86_12515	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LGL86_12520	COG0628	permease
LGL86_12525	COG4783	chaperone-mediated protein folding
LGL86_12530	COG1393	Belongs to the ArsC family
LGL86_12535	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LGL86_12540	COG2233	PERMEase
LGL86_12545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LGL86_12550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LGL86_12555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LGL86_12560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL86_12570	COG0581	inorganic phosphate transmembrane transporter activity
LGL86_12575	COG0573	inorganic phosphate transmembrane transporter activity
LGL86_12580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LGL86_12595	COG2239	Acts as a magnesium transporter
LGL86_12600	COG0443	Heat shock 70 kDa protein
LGL86_12610	COG3121	Chaperone
LGL86_12630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LGL86_12640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LGL86_12645	COG0477	Major facilitator Superfamily
LGL86_12650	COG2205	protein histidine kinase activity
LGL86_12655	COG0745	RESPONSE REGULATOR receiver
LGL86_12660	COG3422	double-strand break repair
LGL86_12665	COG0826	peptidase U32
LGL86_12670	COG1597	lipid kinase activity
LGL86_12685	COG0351	phosphomethylpyrimidine kinase
LGL86_12700	COG0519	Catalyzes the synthesis of GMP from XMP
LGL86_12700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LGL86_12705	COG0516	GMP reductase activity
LGL86_12705	COG0517	IMP dehydrogenase activity
LGL86_12710	COG1570	exodeoxyribonuclease VII activity
LGL86_12715	COG1645	bacterial-type flagellum-dependent swarming motility
LGL86_12725	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL86_12730	COG2976	Protein conserved in bacteria
LGL86_12735	COG0124	histidyl-tRNA synthetase
LGL86_12755	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LGL86_12770	COG4953	penicillin-binding protein 1C
LGL86_12775	COG2373	Large extracellular alpha-helical protein
LGL86_12790	COG2975	iron-sulfur cluster assembly
LGL86_12795	COG0633	Ferredoxin
LGL86_12800	COG0443	Heat shock 70 kDa protein
LGL86_12815	COG0822	iron-sulfur transferase activity
LGL86_12825	COG1959	2 iron, 2 sulfur cluster binding
LGL86_12830	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LGL86_12840	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
LGL86_12845	COG3683	transport system, periplasmic component
LGL86_12850	COG3711	transcriptional antiterminator
LGL86_12855	COG2814	Major facilitator Superfamily
LGL86_12865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LGL86_12865	COG1017	nitric oxide dioxygenase activity
LGL86_12870	COG2188	Transcriptional regulator
LGL86_12880	COG3457	Alanine racemase
LGL86_12885	COG1735	metal-dependent hydrolase with the TIM-barrel fold
LGL86_12900	COG0347	Belongs to the P(II) protein family
LGL86_12905	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LGL86_12905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL86_12910	COG2204	response regulator
LGL86_12915	COG3170	Tfp pilus assembly protein FimV
LGL86_12920	COG2205	protein histidine kinase activity
LGL86_12935	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LGL86_12945	COG0560	Phosphoserine phosphatase
LGL86_12950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL86_12950	COG1263	PTS System
LGL86_12960	COG1737	Transcriptional regulator
LGL86_12965	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LGL86_12975	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LGL86_12985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LGL86_13000	COG0481	GTPase activity
LGL86_13005	COG3086	response to oxidative stress
LGL86_13015	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LGL86_13025	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LGL86_13035	COG0513	Belongs to the DEAD box helicase family
LGL86_13050	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
LGL86_13060	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LGL86_13065	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LGL86_13070	COG0497	DNA recombination
LGL86_13075	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LGL86_13085	COG2867	negative regulation of translational initiation
LGL86_13090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LGL86_13100	COG0582	viral genome integration into host DNA
LGL86_13135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL86_13230	COG3121	Chaperone
LGL86_13260	COG0583	DNA-binding transcription factor activity
LGL86_13335	COG1069	ribulokinase activity
LGL86_13345	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL86_13350	COG1129	ABC transporter
LGL86_13370	COG1620	l-lactate permease
LGL86_13375	COG1304	FMN binding
LGL86_13380	COG0579	oxidoreductase
LGL86_13385	COG1278	Cold shock
LGL86_13415	COG1780	Probably involved in ribonucleotide reductase function
LGL86_13420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LGL86_13430	COG4175	Glycine betaine
LGL86_13435	COG4176	ABC-type proline glycine betaine transport system permease component
LGL86_13440	COG2113	Glycine betaine
LGL86_13450	COG2814	Major facilitator Superfamily
LGL86_13455	COG1846	Transcriptional regulator
LGL86_13465	COG1566	PFAM secretion protein HlyD family protein
LGL86_13470	COG2814	Major facilitator Superfamily
LGL86_13475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL86_13480	COG3118	belongs to the thioredoxin family
LGL86_13485	COG3148	PFAM DTW domain containing protein
LGL86_13490	COG0045	succinate-CoA ligase (ADP-forming) activity
LGL86_13490	COG1042	CoA-binding domain protein
LGL86_13490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LGL86_13495	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LGL86_13500	COG5544	Lipoprotein
LGL86_13525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LGL86_13535	COG2011	ABC-type metal ion transport system permease component
LGL86_13540	COG1464	Belongs to the NlpA lipoprotein family
LGL86_13550	COG1720	tRNA m6t6A37 methyltransferase activity
LGL86_13555	COG0442	prolyl-tRNA aminoacylation
LGL86_13560	COG3015	lipoprotein NlpE involved in copper resistance
LGL86_13570	COG4681	YaeQ
LGL86_13580	COG4568	rho-dependent transcription termination
LGL86_13595	COG0346	lactoylglutathione lyase activity
LGL86_13610	COG0825	malonyl-CoA metabolic process
LGL86_13615	COG0587	DNA-directed DNA polymerase activity
LGL86_13620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LGL86_13640	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LGL86_13645	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
LGL86_13655	COG0750	zinc metalloprotease
LGL86_13660	COG0575	Belongs to the CDS family
LGL86_13680	COG0528	UMP kinase activity
LGL86_13685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LGL86_13700	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LGL86_13705	COG2171	N-acyltransferase activity
LGL86_13720	COG0564	pseudouridine synthase activity
LGL86_13725	COG3098	single-species biofilm formation
LGL86_13740	COG1611	Belongs to the LOG family
LGL86_13750	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LGL86_13755	COG2363	Small membrane protein
LGL86_13760	COG0583	DNA-binding transcription factor activity
LGL86_13770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LGL86_13775	COG2166	iron-sulfur cluster assembly
LGL86_13780	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LGL86_13785	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LGL86_13805	COG0860	N-Acetylmuramoyl-L-alanine amidase
LGL86_13810	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL86_13810	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LGL86_13815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LGL86_13820	COG1074	ATP-dependent DNA helicase activity
LGL86_13825	COG1025	Belongs to the peptidase M16 family
LGL86_13830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LGL86_13835	COG4967	type IV pilus modification protein PilV
LGL86_13860	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LGL86_13865	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LGL86_13875	COG3066	DNA modification
LGL86_13880	COG0861	Integral membrane protein TerC family
LGL86_13885	COG0667	Aldo Keto reductase
LGL86_13890	COG0477	Major facilitator Superfamily
LGL86_13895	COG0318	PFAM AMP-dependent synthetase and ligase
LGL86_13895	COG0204	Acyl-transferase
LGL86_13900	COG1609	Transcriptional regulator
LGL86_13910	COG0583	DNA-binding transcription factor activity
LGL86_13915	COG0583	DNA-binding transcription factor activity
LGL86_13975	COG2165	general secretion pathway protein
LGL86_13985	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LGL86_14015	COG1127	ABC transporter
LGL86_14020	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL86_14030	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LGL86_14040	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LGL86_14045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL86_14050	COG4974	Belongs to the 'phage' integrase family
LGL86_14055	COG0716	FMN binding
LGL86_14065	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LGL86_14075	COG1272	protein, Hemolysin III
LGL86_14095	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LGL86_14100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL86_14105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LGL86_14110	COG0006	proline dipeptidase activity
LGL86_14120	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
LGL86_14130	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LGL86_14135	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LGL86_14140	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LGL86_14155	COG1279	arginine transmembrane transporter activity
LGL86_14165	COG0191	fructose-bisphosphate aldolase activity
LGL86_14170	COG0126	phosphoglycerate kinase activity
LGL86_14175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LGL86_14180	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LGL86_14190	COG1166	arginine decarboxylase activity
LGL86_14195	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LGL86_14210	COG0640	Transcriptional regulator
LGL86_14215	COG3091	SprT-like family
LGL86_14220	COG2356	endonuclease I
LGL86_14225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LGL86_14230	COG0189	ligase activity
LGL86_14235	COG1678	Uncharacterized ACR, COG1678
LGL86_14240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LGL86_14245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL86_14255	COG2805	Type II/IV secretion system protein
LGL86_14260	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LGL86_14265	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LGL86_14270	COG0762	integral membrane protein
LGL86_14275	COG1872	DUF167
LGL86_14280	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LGL86_14285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL86_14300	COG3171	Protein conserved in bacteria
LGL86_14310	COG1194	a g-specific adenine glycosylase
LGL86_14315	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LGL86_14320	COG0741	lytic transglycosylase activity
LGL86_14365	COG1105	Belongs to the carbohydrate kinase PfkB family
LGL86_14370	COG1882	Formate acetyltransferase
LGL86_14375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LGL86_14380	COG0814	amino acid
LGL86_14395	COG1028	Short-chain dehydrogenase reductase Sdr
LGL86_14400	COG1535	isochorismatase
LGL86_14400	COG3433	isochorismatase activity
LGL86_14405	COG1021	2,3-dihydroxybenzoate-AMP ligase
LGL86_14410	COG1169	isochorismate synthase
LGL86_14415	COG4592	Periplasmic binding protein
LGL86_14425	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL86_14430	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LGL86_14435	COG1120	ATPase activity
LGL86_14445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LGL86_14450	COG3251	PFAM MbtH domain protein
LGL86_14460	COG4774	siderophore transport
LGL86_14465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LGL86_14490	COG4964	Belongs to the GSP D family
LGL86_14535	COG0848	biopolymer transport protein
LGL86_14540	COG0811	peptide transport
LGL86_14545	COG0626	cystathionine gamma-synthase activity
LGL86_14550	COG0586	Pfam SNARE associated Golgi protein
LGL86_14555	COG2207	Transcriptional regulator
LGL86_14560	COG1979	alcohol dehydrogenase
LGL86_14565	COG0656	L-ascorbic acid biosynthetic process
LGL86_14575	COG2132	Multicopper oxidase
LGL86_14590	COG2249	NAD(P)H dehydrogenase (quinone) activity
LGL86_14595	COG0583	DNA-binding transcription factor activity
LGL86_14600	COG0187	DNA topoisomerase II activity
LGL86_14605	COG3150	esterase
LGL86_14610	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LGL86_14615	COG3151	Protein conserved in bacteria
LGL86_14620	COG0494	nUDIX hydrolase
LGL86_14625	COG1538	Outer membrane efflux protein
LGL86_14630	COG5463	Belongs to the UPF0441 family
LGL86_14635	COG0754	glutathionylspermidine amidase activity
LGL86_14640	COG3384	dioxygenase
LGL86_14645	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LGL86_14660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LGL86_14660	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LGL86_14670	COG3025	triphosphatase activity
LGL86_14675	COG4991	sh3 domain protein
LGL86_14680	COG0617	tRNA 3'-terminal CCA addition
LGL86_14685	COG1968	undecaprenyl-diphosphatase activity
LGL86_14690	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LGL86_14695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LGL86_14700	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LGL86_14705	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LGL86_14710	COG0358	DNA primase activity
LGL86_14740	COG1028	Short-chain dehydrogenase reductase Sdr
LGL86_14775	COG0463	Glycosyl transferase, family 2
LGL86_14810	COG3210	domain, Protein
LGL86_14820	COG2831	hemolysin activation secretion protein
LGL86_14825	COG1902	pentaerythritol trinitrate reductase activity
LGL86_14825	COG0446	pyridine nucleotide-disulphide oxidoreductase
LGL86_14840	COG1451	nucleotide metabolic process
LGL86_14845	COG0673	inositol 2-dehydrogenase activity
LGL86_14850	COG0861	Integral membrane protein TerC family
LGL86_14855	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LGL86_14865	COG2721	sulfolactate sulfo-lyase activity
LGL86_14880	COG2271	Major facilitator Superfamily
LGL86_14895	COG0586	Pfam SNARE associated Golgi protein
LGL86_14910	COG4575	ribosome binding
LGL86_14915	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
LGL86_14925	COG2259	Doxx family
LGL86_14930	COG0583	DNA-binding transcription factor activity
LGL86_14935	COG1741	Belongs to the pirin family
LGL86_14950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LGL86_14965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LGL86_14970	COG2823	Periplasmic or secreted lipoprotein
LGL86_14975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LGL86_14980	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LGL86_14985	COG2198	Histidine kinase
LGL86_14985	COG0784	Response regulator, receiver
LGL86_14985	COG5002	protein histidine kinase activity
LGL86_14990	COG1242	4 iron, 4 sulfur cluster binding
LGL86_14995	COG0069	glutamate synthase activity
LGL86_14995	COG0070	glutamate synthase
LGL86_14995	COG0067	glutamate synthase
LGL86_15000	COG0493	'glutamate synthase
LGL86_15010	COG2969	positive regulation of protein catabolic process
LGL86_15015	COG0625	glutathione transferase activity
LGL86_15020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LGL86_15025	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LGL86_15030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LGL86_15035	COG3105	Protein conserved in bacteria
LGL86_15040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LGL86_15050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LGL86_15055	COG5007	Belongs to the BolA IbaG family
LGL86_15060	COG3113	response to antibiotic
LGL86_15065	COG2854	intermembrane phospholipid transfer
LGL86_15070	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LGL86_15075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LGL86_15080	COG1127	ABC transporter
LGL86_15085	COG0530	calcium, potassium:sodium antiporter activity
LGL86_15090	COG0517	IMP dehydrogenase activity
LGL86_15090	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LGL86_15095	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LGL86_15100	COG3117	lipopolysaccharide transmembrane transporter activity
LGL86_15105	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LGL86_15110	COG1137	ATPase activity
LGL86_15115	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LGL86_15135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LGL86_15140	COG0540	Belongs to the ATCase OTCase family
LGL86_15145	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LGL86_15155	COG0366	Alpha amylase catalytic
LGL86_15160	COG1263	PTS System
LGL86_15160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LGL86_15170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LGL86_15180	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LGL86_15185	COG3783	Cytochrome b(562)
LGL86_15190	COG0312	modulator of DNA gyrase
LGL86_15195	COG3028	Belongs to the UPF0307 family
LGL86_15200	COG2732	(Barnase) inhibitor
LGL86_15205	COG4290	ribonuclease
LGL86_15215	COG1289	transmembrane transporter activity
LGL86_15220	COG1566	PFAM secretion protein HlyD family protein
LGL86_15230	COG0583	DNA-binding transcription factor activity
LGL86_15235	COG0312	modulator of DNA gyrase
LGL86_15240	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LGL86_15245	COG3164	Protein of unknown function
LGL86_15255	COG0424	maF-like protein
LGL86_15260	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LGL86_15265	COG1792	Involved in formation and maintenance of cell shape
LGL86_15270	COG1077	Cell shape determining protein MreB Mrl
LGL86_15275	COG2199	diguanylate cyclase activity
LGL86_15275	COG2200	EAL domain
LGL86_15280	COG0604	alcohol dehydrogenase
LGL86_15285	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LGL86_15290	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LGL86_15300	COG0511	ligase activity, forming carbon-carbon bonds
LGL86_15305	COG0439	Biotin carboxylase
LGL86_15310	COG3924	membrane
LGL86_15315	COG4145	pantothenate transmembrane transporter activity
LGL86_15320	COG2264	protein methyltransferase activity
LGL86_15325	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL86_15330	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LGL86_15340	COG1560	Kdo2-lipid A biosynthetic process
LGL86_15350	COG1346	cytolysis
LGL86_15355	COG1380	Effector of murein hydrolase LrgA
LGL86_15360	COG0583	DNA-binding transcription factor activity
LGL86_15365	COG0025	NhaP-type Na H and K H
LGL86_15370	COG2252	PERMEase
LGL86_15385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LGL86_15390	COG2315	Protein conserved in bacteria
LGL86_15395	COG1448	Aminotransferase
LGL86_15420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LGL86_15425	COG0735	belongs to the Fur family
LGL86_15430	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LGL86_15435	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LGL86_15440	COG2937	Belongs to the GPAT DAPAT family
LGL86_15460	COG4580	involved in the transport of maltose and maltodextrins
LGL86_15475	COG2182	Extracellular solute-binding protein
LGL86_15480	COG1175	transmembrane transport
LGL86_15485	COG3833	ABC-type maltose transport systems, permease component
LGL86_15490	COG3223	Belongs to the PsiE family
LGL86_15500	COG0527	aspartate kinase activity
LGL86_15515	COG3328	transposase activity
LGL86_15540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LGL86_15625	COG0583	DNA-binding transcription factor activity
LGL86_15660	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LGL86_15700	COG0138	bifunctional purine biosynthesis protein purh
LGL86_15705	COG0151	Belongs to the GarS family
LGL86_15725	COG1515	deoxyribonuclease V activity
LGL86_15730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LGL86_15735	COG2816	NAD+ diphosphatase activity
LGL86_15740	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LGL86_15755	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LGL86_15760	COG2104	thiamine diphosphate biosynthetic process
LGL86_15765	COG2022	thiamine diphosphate biosynthetic process
LGL86_15775	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LGL86_15780	COG0085	RNA polymerase activity
LGL86_15785	COG0222	ribosome binding
LGL86_15790	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LGL86_15800	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LGL86_15805	COG0250	Participates in transcription elongation, termination and antitermination
LGL86_15850	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LGL86_15875	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LGL86_15880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LGL86_15885	COG1739	Uncharacterized protein family UPF0029
LGL86_15895	COG1250	3-hydroxyacyl-CoA dehydrogenase
LGL86_15895	COG1024	Enoyl-CoA hydratase
LGL86_15905	COG0543	2 iron, 2 sulfur cluster binding
LGL86_15920	COG0250	Participates in transcription elongation, termination and antitermination
LGL86_15935	COG0805	protein transport
LGL86_15940	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL86_15945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LGL86_15950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LGL86_15955	COG3165	ubiquinone biosynthetic process from chorismate
LGL86_15960	COG2226	methyltransferase
LGL86_15965	COG1322	Protein conserved in bacteria
LGL86_15970	COG0586	Pfam SNARE associated Golgi protein
LGL86_15975	COG1966	Carbon starvation protein
LGL86_15990	COG0412	Dienelactone hydrolase
LGL86_15995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LGL86_16000	COG0583	DNA-binding transcription factor activity
LGL86_16005	COG0697	spore germination
LGL86_16015	COG0584	glycerophosphoryl diester phosphodiesterase
LGL86_16025	COG0395	ABC-type sugar transport system, permease component
LGL86_16030	COG1175	transmembrane transport
LGL86_16035	COG1653	transport
LGL86_16070	COG0410	ABC transporter
LGL86_16080	COG4177	L-phenylalanine transmembrane transporter activity
LGL86_16100	COG1929	Belongs to the glycerate kinase type-1 family
LGL86_16105	COG2610	gluconate transmembrane transporter activity
LGL86_16110	COG3835	regulator
LGL86_16120	COG2177	Part of the ABC transporter FtsEX involved in
LGL86_16125	COG2884	Cell division ATP-binding protein ftsE
LGL86_16130	COG0552	protein localization to endoplasmic reticulum
LGL86_16130	COG0552	protein localization to endoplasmic reticulum
LGL86_16135	COG0742	ribosomal rna small subunit methyltransferase
LGL86_16140	COG3776	membrane
LGL86_16155	COG3714	YhhN family
LGL86_16170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LGL86_16180	COG0247	lactate metabolic process
LGL86_16190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LGL86_16200	COG2271	Major facilitator Superfamily
LGL86_16205	COG0584	glycerophosphoryl diester phosphodiesterase
LGL86_16210	COG0561	phosphatase activity
LGL86_16215	COG2267	carboxylic ester hydrolase activity
LGL86_16220	COG1280	lysine exporter protein (LysE YggA)
LGL86_16225	COG0514	ATP-dependent DNA helicase (RecQ)
LGL86_16230	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
LGL86_16235	COG2050	protein possibly involved in aromatic compounds catabolism
LGL86_16255	COG5564	TIM-barrel signal transduction protein
LGL86_16260	COG5441	Belongs to the UPF0261 family
LGL86_16270	COG0210	DNA helicase
LGL86_16275	COG1011	Hydrolase
LGL86_16280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LGL86_16285	COG3159	Protein conserved in bacteria
LGL86_16290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LGL86_16295	COG5567	small periplasmic lipoprotein
LGL86_16305	COG3072	Adenylate cyclase
LGL86_16310	COG0181	hydroxymethylbilane synthase activity
LGL86_16315	COG1587	Uroporphyrinogen-III synthase
LGL86_16320	COG2959	enzyme of heme biosynthesis
LGL86_16325	COG3071	HemY protein
LGL86_16375	COG2244	polysaccharide biosynthetic process
LGL86_16380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LGL86_16385	COG0456	acetyltransferase
LGL86_16390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LGL86_16395	COG1088	dTDP-glucose 4,6-dehydratase activity
LGL86_16400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LGL86_16405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LGL86_16410	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LGL86_16415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LGL86_16420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LGL86_16425	COG3118	belongs to the thioredoxin family
LGL86_16435	COG0248	Ppx GppA phosphatase
LGL86_16445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LGL86_16460	COG3397	chitin binding
LGL86_16470	COG0129	dihydroxy-acid dehydratase activity
LGL86_16480	COG3978	acetolactate synthase activity
LGL86_16500	COG3085	chromosome segregation
LGL86_16505	COG0583	DNA-binding transcription factor activity
LGL86_16580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL86_16590	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL86_16590	COG0678	peroxiredoxin activity
LGL86_16595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LGL86_16630	COG1629	transport
LGL86_16635	COG0165	Argininosuccinate lyase
LGL86_16640	COG0137	argininosuccinate synthase activity
LGL86_16645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LGL86_16690	COG0460	homoserine dehydrogenase
LGL86_16690	COG0527	aspartate kinase activity
LGL86_16695	COG0626	cystathionine gamma-synthase activity
LGL86_16700	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
LGL86_16710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LGL86_16715	COG1609	Transcriptional regulator
LGL86_16720	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LGL86_16725	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LGL86_16730	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LGL86_16735	COG1575	Belongs to the MenA family. Type 1 subfamily
LGL86_16740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LGL86_16745	COG3074	FtsZ-dependent cytokinesis
LGL86_16750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LGL86_16755	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LGL86_16760	COG1494	fructose-1,6-bisphosphatase
LGL86_16765	COG2814	Major facilitator Superfamily
LGL86_16775	COG3152	Membrane
LGL86_16790	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LGL86_16800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LGL86_16805	COG3678	ATP-independent chaperone mediated protein folding
LGL86_16810	COG0745	RESPONSE REGULATOR receiver
LGL86_16815	COG2205	protein histidine kinase activity
LGL86_16820	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LGL86_16825	COG1045	serine acetyltransferase
LGL86_16830	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LGL86_16835	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LGL86_16840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LGL86_16845	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LGL86_16850	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LGL86_16855	COG4942	peptidase
LGL86_16860	COG2861	carbohydrate metabolic process
LGL86_16875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LGL86_16880	COG0859	PFAM glycosyl transferase family 9
LGL86_16885	COG0859	PFAM glycosyl transferase family 9
LGL86_16890	COG1519	Transferase
LGL86_16910	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LGL86_16915	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LGL86_16920	COG2003	Belongs to the UPF0758 family
LGL86_16925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LGL86_16930	COG0756	dUTP diphosphatase activity
LGL86_16935	COG1309	transcriptional regulator
LGL86_16940	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LGL86_16945	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LGL86_16950	COG1561	YicC-like family, N-terminal region
LGL86_16965	COG5001	Diguanylate cyclase
LGL86_16970	COG1024	Enoyl-CoA hydratase
LGL86_16975	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LGL86_16990	COG2860	membrane
LGL86_16995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LGL86_17005	COG1758	RNA polymerase activity
LGL86_17010	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LGL86_17015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LGL86_17020	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LGL86_17025	COG0786	glutamate:sodium symporter activity
LGL86_17030	COG2233	PERMEase
LGL86_17035	COG2982	Protein involved in outer membrane biogenesis
LGL86_17040	COG0456	acetyltransferase
LGL86_17055	COG1011	Hydrolase
LGL86_17070	COG3852	Histidine kinase
LGL86_17080	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LGL86_17090	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LGL86_17095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL86_17095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LGL86_17100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LGL86_17105	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LGL86_17110	COG3084	Protein conserved in bacteria
LGL86_17120	COG1763	Mo-molybdopterin cofactor biosynthetic process
LGL86_17145	COG2186	Transcriptional regulator
LGL86_17150	COG1609	Transcriptional regulator
LGL86_17155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LGL86_17165	COG1172	Belongs to the binding-protein-dependent transport system permease family
LGL86_17170	COG1129	ABC transporter
LGL86_17175	COG1869	D-ribose catabolic process
LGL86_17180	COG3158	transport of potassium into the cell
LGL86_17185	COG0714	Associated with various cellular activities
LGL86_17190	COG2425	protein containing a von Willebrand factor type A (vWA) domain
LGL86_17200	COG2502	aspartate--ammonia ligase
LGL86_17205	COG1522	sequence-specific DNA binding
LGL86_17210	COG0716	FMN binding
LGL86_17215	COG0445	tRNA wobble uridine modification
LGL86_17220	COG0357	Ribosomal RNA small subunit methyltransferase G
LGL86_17225	COG3312	ion transport
LGL86_17230	COG0356	it plays a direct role in the translocation of protons across the membrane
LGL86_17240	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LGL86_17250	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LGL86_17255	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LGL86_17265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LGL86_17280	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LGL86_17285	COG0573	inorganic phosphate transmembrane transporter activity
LGL86_17290	COG0581	inorganic phosphate transmembrane transporter activity
LGL86_17300	COG0704	Plays a role in the regulation of phosphate uptake
LGL86_17305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LGL86_17310	COG0765	amino acid transport
LGL86_17315	COG0765	amino acid transport
LGL86_17320	COG2252	PERMEase
LGL86_17325	COG0840	transmembrane signaling receptor activity
LGL86_17335	COG3121	Chaperone
LGL86_17350	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LGL86_17355	COG0706	membrane insertase activity
LGL86_17365	COG0594	ribonuclease P activity
LGL86_17370	COG0230	Belongs to the bacterial ribosomal protein bL34 family