locus-tag	class	description
UGYR_00010	COG0308	aminopeptidase N
UGYR_00015	COG0167	dihydroorotate dehydrogenase activity
UGYR_00025	COG3217	Mosc domain protein beta barrel domain protein
UGYR_00025	COG0633	Ferredoxin
UGYR_00030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
UGYR_00030	COG0116	Belongs to the methyltransferase superfamily
UGYR_00035	COG0488	(ABC) transporter
UGYR_00040	COG2995	paraquat-inducible protein a
UGYR_00045	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
UGYR_00045	COG3008	intermembrane lipid transfer
UGYR_00050	COG3009	Protein conserved in bacteria
UGYR_00055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
UGYR_00060	COG1067	ATP-dependent peptidase activity
UGYR_00065	COG3120	sequence-specific DNA binding
UGYR_00070	COG2885	chlorophyll binding
UGYR_00070	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
UGYR_00075	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
UGYR_00080	COG3070	regulator of competence-specific genes
UGYR_00085	COG1289	transmembrane transporter activity
UGYR_00090	COG3304	Inner membrane component domain
UGYR_00095	COG0210	DNA helicase
UGYR_00100	COG1803	Methylglyoxal synthase
UGYR_00110	COG1832	CoA-binding protein
UGYR_00115	COG3785	DNA binding
UGYR_00120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
UGYR_00125	COG1254	Belongs to the acylphosphatase family
UGYR_00130	COG2920	part of a sulfur-relay system
UGYR_00140	COG0288	reversible hydration of carbon dioxide
UGYR_00160	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
UGYR_00165	COG2943	transferase activity, transferring hexosyl groups
UGYR_00175	COG3104	oligopeptide transport
UGYR_00185	COG1560	Kdo2-lipid A biosynthetic process
UGYR_00195	COG0628	permease
UGYR_00220	COG0418	dihydroorotase activity
UGYR_00225	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
UGYR_00235	COG1530	ribonuclease E activity
UGYR_00240	COG0564	pseudouridine synthase activity
UGYR_00250	COG1399	metal-binding, possibly nucleic acid-binding protein
UGYR_00255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
UGYR_00265	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
UGYR_00270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
UGYR_00275	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_00280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UGYR_00285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UGYR_00290	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
UGYR_00295	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
UGYR_00300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
UGYR_00305	COG0470	DNA polymerase III
UGYR_00310	COG0084	hydrolase, TatD family'
UGYR_00315	COG1263	PTS System
UGYR_00315	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_00320	COG0537	adenosine 5'-monophosphoramidase activity
UGYR_00325	COG5633	Lipoprotein
UGYR_00330	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
UGYR_00335	COG0510	thiamine kinase activity
UGYR_00345	COG3150	esterase
UGYR_00350	COG1252	NADH dehydrogenase
UGYR_00355	COG3134	Outer membrane lipoprotein
UGYR_00360	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
UGYR_00365	COG4591	ABC-type transport system involved in lipoprotein release permease component
UGYR_00375	COG4591	ABC-type transport system involved in lipoprotein release permease component
UGYR_00385	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
UGYR_00395	COG2850	peptidyl-arginine hydroxylation
UGYR_00400	COG2205	protein histidine kinase activity
UGYR_00405	COG0745	RESPONSE REGULATOR receiver
UGYR_00415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
UGYR_00420	COG2915	High frequency lysogenization protein hflD homolog
UGYR_00425	COG0482	sulfurtransferase activity
UGYR_00435	COG1187	pseudouridine synthase activity
UGYR_00440	COG0538	isocitrate dehydrogenase activity
UGYR_00445	COG2771	luxR family
UGYR_00450	COG3916	Acyl-homoserine-lactone synthase
UGYR_00455	COG2723	6-phospho-beta-galactosidase activity
UGYR_00460	COG0339	signal peptide processing
UGYR_00470	COG3493	citrate carrier protein
UGYR_00475	COG4565	transcriptional regulatory protein
UGYR_00480	COG3290	protein histidine kinase activity
UGYR_00485	COG0471	metal ion transport
UGYR_00525	COG4977	sequence-specific DNA binding
UGYR_00530	COG1702	phosphate starvation-inducible protein PhoH
UGYR_00535	COG0387	Pfam Sodium calcium exchanger
UGYR_00540	COG2375	cellular response to nickel ion
UGYR_00545	COG3850	Histidine kinase
UGYR_00550	COG1294	oxidase, subunit
UGYR_00555	COG1271	oxidase subunit
UGYR_00560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UGYR_00565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
UGYR_00570	COG3138	arginine N-succinyltransferase
UGYR_00580	COG3724	N-succinylarginine dihydrolase activity
UGYR_00600	COG1228	amidohydrolase
UGYR_00610	COG0402	S-adenosylhomocysteine deaminase activity
UGYR_00630	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
UGYR_00635	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
UGYR_00640	COG3383	formate dehydrogenase (NAD+) activity
UGYR_00645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
UGYR_00650	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
UGYR_00660	COG3260	NADH ubiquinone oxidoreductase 20
UGYR_00665	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_00670	COG3261	NADH dehydrogenase
UGYR_00670	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
UGYR_00675	COG0650	Formate hydrogenlyase subunit 4
UGYR_00680	COG0651	ATP synthesis coupled electron transport
UGYR_00685	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
UGYR_00695	COG0375	protein maturation
UGYR_00700	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
UGYR_00705	COG0298	carbon dioxide binding
UGYR_00710	COG0409	Hydrogenase expression formation protein
UGYR_00715	COG0309	Hydrogenase expression formation protein (HypE)
UGYR_00755	COG2207	Transcriptional regulator
UGYR_00755	COG3708	Transcriptional regulator
UGYR_00760	COG0012	GTP binding
UGYR_00770	COG0193	aminoacyl-tRNA hydrolase activity
UGYR_00780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
UGYR_00790	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
UGYR_00795	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
UGYR_00800	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
UGYR_00805	COG2890	protein-(glutamine-N5) methyltransferase activity
UGYR_00810	COG3094	Invasion gene expression up-regulator, SirB
UGYR_00815	COG2912	Transglutaminase-like superfamily
UGYR_00820	COG2877	3-deoxy-8-phosphooctulonate synthase activity
UGYR_00825	COG0659	secondary active sulfate transmembrane transporter activity
UGYR_00840	COG3706	GGDEF domain
UGYR_00865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
UGYR_00875	COG3381	protein complex oligomerization
UGYR_00895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UGYR_00905	COG0673	inositol 2-dehydrogenase activity
UGYR_00910	COG0728	peptidoglycan biosynthetic process
UGYR_00935	COG3102	Protein conserved in bacteria
UGYR_00940	COG3142	Participates in the control of copper homeostasis
UGYR_00955	COG3788	relative of glutathione S-transferase, MAPEG superfamily
UGYR_00960	COG1801	Protein of unknown function DUF72
UGYR_00970	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
UGYR_00975	COG0494	nUDIX hydrolase
UGYR_00985	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
UGYR_00995	COG2255	four-way junction helicase activity
UGYR_01000	COG3104	oligopeptide transport
UGYR_01005	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UGYR_01010	COG1121	(ABC) transporter
UGYR_01015	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
UGYR_01020	COG0739	heme binding
UGYR_01025	COG1560	Kdo2-lipid A biosynthetic process
UGYR_01030	COG0469	pyruvate kinase activity
UGYR_01035	COG1737	Transcriptional regulator
UGYR_01040	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
UGYR_01045	COG0800	Aldolase
UGYR_01055	COG2076	Multidrug Resistance protein
UGYR_01060	COG0251	oxidation-reduction process
UGYR_01065	COG1199	ATP-dependent helicase activity
UGYR_01070	COG1214	PFAM Peptidase M22, glycoprotease
UGYR_01075	COG3065	identical protein binding
UGYR_01080	COG0318	PFAM AMP-dependent synthetase and ligase
UGYR_01085	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
UGYR_01090	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
UGYR_01095	COG2894	cell division
UGYR_01100	COG0850	regulation of cytokinetic process
UGYR_01105	COG3100	YcgL domain-containing protein
UGYR_01110	COG0179	Fumarylacetoacetate (FAA) hydrolase
UGYR_01115	COG2983	Belongs to the UPF0260 family
UGYR_01130	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
UGYR_01140	COG2719	SpoVR family
UGYR_01145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
UGYR_01150	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
UGYR_01165	COG2199	diguanylate cyclase activity
UGYR_01165	COG2200	EAL domain
UGYR_01165	COG2202	Pas domain
UGYR_01185	COG2718	Belongs to the UPF0229 family
UGYR_01190	COG2766	serine protein kinase
UGYR_01195	COG3713	MltA-interacting MipA family protein
UGYR_01215	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UGYR_01220	COG3139	Protein of unknown function (DUF1315)
UGYR_01225	COG1335	isochorismatase
UGYR_01230	COG0252	asparaginase activity
UGYR_01235	COG0616	signal peptide processing
UGYR_01240	COG0778	Nitroreductase
UGYR_01250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
UGYR_01260	COG0494	nUDIX hydrolase
UGYR_01265	COG0708	Exodeoxyribonuclease III
UGYR_01295	COG0788	formyltetrahydrofolate deformylase activity
UGYR_01305	COG1752	Esterase of the alpha-beta hydrolase superfamily
UGYR_01310	COG0745	RESPONSE REGULATOR receiver
UGYR_01325	COG1435	thymidine kinase activity
UGYR_01330	COG1012	belongs to the aldehyde dehydrogenase family
UGYR_01330	COG1454	alcohol dehydrogenase
UGYR_01335	COG2095	MarC family integral membrane protein
UGYR_01345	COG4166	transmembrane transport
UGYR_01360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UGYR_01375	COG3099	Belongs to the UPF0263 family
UGYR_01380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UGYR_01400	COG2350	Protein conserved in bacteria
UGYR_01450	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
UGYR_01455	COG1607	acyl-coa hydrolase
UGYR_01480	COG3047	cAMP biosynthetic process
UGYR_01495	COG0133	tryptophan synthase activity
UGYR_01500	COG0134	indole-3-glycerol-phosphate synthase activity
UGYR_01500	COG0135	phosphoribosylanthranilate isomerase activity
UGYR_01510	COG0512	Glutamine amidotransferase of anthranilate synthase
UGYR_01520	COG0613	PHP domain protein
UGYR_01525	COG0009	L-threonylcarbamoyladenylate synthase
UGYR_01530	COG1187	pseudouridine synthase activity
UGYR_01540	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_01545	COG0616	signal peptide processing
UGYR_01555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
UGYR_01560	COG0583	DNA-binding transcription factor activity
UGYR_01575	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
UGYR_01580	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
UGYR_01585	COG0671	phosphoesterase, PA-phosphatase related
UGYR_01590	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
UGYR_01595	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
UGYR_01615	COG0023	Translation Initiation Factor
UGYR_01625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
UGYR_01630	COG5001	Diguanylate cyclase
UGYR_01630	COG5002	protein histidine kinase activity
UGYR_01630	COG3447	MASE1 domain protein
UGYR_01635	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
UGYR_01640	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
UGYR_01650	COG4659	FMN binding
UGYR_01660	COG3708	Transcriptional regulator
UGYR_01660	COG2207	Transcriptional regulator
UGYR_01675	COG4657	Part of a membrane complex involved in electron transport
UGYR_01685	COG2759	Belongs to the formate--tetrahydrofolate ligase family
UGYR_01695	COG0673	inositol 2-dehydrogenase activity
UGYR_01700	COG0385	Bile acid
UGYR_01705	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
UGYR_01710	COG5339	Protein conserved in bacteria
UGYR_01715	COG1482	cell wall glycoprotein biosynthetic process
UGYR_01720	COG0114	fumarate hydratase activity
UGYR_01730	COG1940	carbohydrate kinase activity
UGYR_01735	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
UGYR_01755	COG1742	UPF0060 membrane protein
UGYR_01760	COG4221	oxidoreductase activity
UGYR_01765	COG3023	N-Acetylmuramoyl-L-alanine amidase
UGYR_01785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
UGYR_01825	COG1011	Hydrolase
UGYR_01835	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
UGYR_01840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
UGYR_01845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UGYR_01850	COG0589	response to stress
UGYR_01880	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
UGYR_01885	COG3623	hexulose-6-phosphate isomerase
UGYR_01890	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
UGYR_01895	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
UGYR_01905	COG0531	amino acid
UGYR_01915	COG0745	RESPONSE REGULATOR receiver
UGYR_01920	COG2205	protein histidine kinase activity
UGYR_01935	COG2207	Transcriptional regulator
UGYR_01940	COG1881	PFAM PEBP family protein
UGYR_01950	COG3591	Belongs to the peptidase S1B family
UGYR_01955	COG1643	Atp-dependent helicase
UGYR_01965	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
UGYR_01970	COG3784	Protein of unknown function (DUF1318)
UGYR_01985	COG2911	Protein conserved in bacteria
UGYR_01990	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
UGYR_01995	COG3187	Heat shock protein
UGYR_02000	COG3042	response to heat
UGYR_02005	COG1285	pathogenesis
UGYR_02015	COG0674	pyruvate-flavodoxin oxidoreductase activity
UGYR_02015	COG1013	pyruvate-flavodoxin oxidoreductase activity
UGYR_02015	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_02015	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
UGYR_02030	COG4166	transmembrane transport
UGYR_02035	COG2866	Carboxypeptidase
UGYR_02040	COG4948	Mandelate Racemase Muconate Lactonizing
UGYR_02045	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
UGYR_02065	COG3768	UPF0283 membrane protein
UGYR_02070	COG3106	COG3106 Predicted ATPase
UGYR_02080	COG1983	PspC domain protein
UGYR_02090	COG1842	Phage shock protein A
UGYR_02095	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
UGYR_02115	COG4166	transmembrane transport
UGYR_02120	COG4168	peptide transport system, permease
UGYR_02125	COG4171	peptide transport system, permease
UGYR_02130	COG4172	Belongs to the ABC transporter superfamily
UGYR_02135	COG4172	Belongs to the ABC transporter superfamily
UGYR_02145	COG3104	oligopeptide transport
UGYR_02155	COG0484	heat shock protein binding
UGYR_02200	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
UGYR_02205	COG3133	Outer membrane lipoprotein
UGYR_02210	COG1846	Transcriptional regulator
UGYR_02215	COG4989	oxidoreductase activity
UGYR_02220	COG3313	Fe-S protein
UGYR_02225	COG2194	sulfuric ester hydrolase activity
UGYR_02230	COG1309	transcriptional regulator
UGYR_02235	COG1902	pentaerythritol trinitrate reductase activity
UGYR_02240	COG0346	lactoylglutathione lyase activity
UGYR_02250	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
UGYR_02255	COG0791	NLP P60 protein
UGYR_02260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
UGYR_02265	COG1609	Transcriptional regulator
UGYR_02270	COG0583	DNA-binding transcription factor activity
UGYR_02275	COG2814	Major facilitator Superfamily
UGYR_02280	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
UGYR_02285	COG0307	riboflavin synthase, alpha
UGYR_02315	COG0469	pyruvate kinase activity
UGYR_02320	COG4238	major outer membrane lipoprotein
UGYR_02325	COG1388	LysM domain
UGYR_02325	COG1376	ErfK ybiS ycfS ynhG family protein
UGYR_02330	COG2166	iron-sulfur cluster assembly
UGYR_02340	COG0719	Fe-S assembly protein
UGYR_02345	COG0396	ATPase activity
UGYR_02350	COG0719	Fe-S assembly protein
UGYR_02355	COG0316	Belongs to the HesB IscA family
UGYR_02360	COG2050	protein possibly involved in aromatic compounds catabolism
UGYR_02365	COG0247	lactate metabolic process
UGYR_02365	COG0277	FAD linked oxidase domain protein
UGYR_02370	COG0628	permease
UGYR_02375	COG0574	Belongs to the PEP-utilizing enzyme family
UGYR_02375	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
UGYR_02380	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
UGYR_02385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UGYR_02390	COG4771	TonB-dependent receptor
UGYR_02395	COG3720	iron ion transport
UGYR_02400	COG4558	Periplasmic binding protein
UGYR_02405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UGYR_02410	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
UGYR_02420	COG0095	Lipoate-protein ligase
UGYR_02425	COG0791	NLP P60 protein
UGYR_02430	COG2076	Multidrug Resistance protein
UGYR_02435	COG2076	Multidrug Resistance protein
UGYR_02440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
UGYR_02455	COG0463	Glycosyl transferase, family 2
UGYR_02460	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UGYR_02465	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
UGYR_02470	COG4139	cobalamin transport
UGYR_02515	COG2314	TM2 domain
UGYR_02520	COG0776	regulation of translation
UGYR_02595	COG0803	Belongs to the bacterial solute-binding protein 9 family
UGYR_02600	COG1121	(ABC) transporter
UGYR_02605	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UGYR_02610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
UGYR_02625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UGYR_02630	COG1988	membrane-bound metal-dependent
UGYR_02640	COG3023	N-Acetylmuramoyl-L-alanine amidase
UGYR_02650	COG2814	Major facilitator Superfamily
UGYR_02655	COG0501	Belongs to the peptidase M48B family
UGYR_02660	COG0793	Belongs to the peptidase S41A family
UGYR_02670	COG1956	GAF domain-containing protein
UGYR_02675	COG2995	paraquat-inducible protein a
UGYR_02680	COG3008	intermembrane lipid transfer
UGYR_02685	COG4251	negative regulation of phosphorylation
UGYR_02685	COG5001	Diguanylate cyclase
UGYR_02685	COG2203	Gaf domain
UGYR_02685	COG3706	GGDEF domain
UGYR_02800	COG4695	Portal protein
UGYR_02895	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
UGYR_02940	COG4974	Belongs to the 'phage' integrase family
UGYR_02950	COG1276	copper resistance
UGYR_02955	COG2372	response to copper ion
UGYR_02960	COG1528	Iron-storage protein
UGYR_02975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
UGYR_02980	COG1770	oligopeptidase
UGYR_02995	COG3141	response to X-ray
UGYR_03000	COG0513	Belongs to the DEAD box helicase family
UGYR_03020	COG0494	nUDIX hydrolase
UGYR_03025	COG1760	l-serine dehydratase
UGYR_03030	COG1253	flavin adenine dinucleotide binding
UGYR_03035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_03035	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_03040	COG3715	PTS system
UGYR_03045	COG3716	PTS system mannose fructose sorbose family IID component
UGYR_03050	COG4811	Protein of unknown function (DUF986)
UGYR_03055	COG1971	Probably functions as a manganese efflux pump
UGYR_03075	COG1960	acyl-CoA dehydrogenase activity
UGYR_03085	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
UGYR_03115	COG2226	methyltransferase
UGYR_03120	COG0768	penicillin binding
UGYR_03130	COG1278	Cold shock
UGYR_03140	COG1113	amino acid transport
UGYR_03180	COG2207	Transcriptional regulator
UGYR_03195	COG1132	(ABC) transporter
UGYR_03205	COG3706	GGDEF domain
UGYR_03205	COG4251	negative regulation of phosphorylation
UGYR_03205	COG5001	Diguanylate cyclase
UGYR_03205	COG2203	Gaf domain
UGYR_03225	COG1181	Belongs to the D-alanine--D-alanine ligase family
UGYR_03245	COG1278	Cold shock
UGYR_03250	COG1278	Cold shock
UGYR_03265	COG1917	Cupin 2, conserved barrel domain protein
UGYR_03265	COG2169	Transcriptional regulator
UGYR_03270	COG1447	Phosphotransferase system cellobiose-specific component IIA
UGYR_03275	COG2723	6-phospho-beta-galactosidase activity
UGYR_03280	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
UGYR_03285	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
UGYR_03295	COG1187	pseudouridine synthase activity
UGYR_03305	COG3122	Protein conserved in bacteria
UGYR_03325	COG2235	arginine
UGYR_03340	COG0076	glutamate decarboxylase activity
UGYR_03345	COG0531	amino acid
UGYR_03380	COG2153	protein acetylation
UGYR_03390	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
UGYR_03425	COG0840	transmembrane signaling receptor activity
UGYR_03450	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
UGYR_03455	COG0322	excinuclease ABC activity
UGYR_03460	COG2197	response regulator
UGYR_03480	COG1113	amino acid transport
UGYR_03485	COG1982	Orn Lys Arg decarboxylase major
UGYR_03490	COG0531	amino acid
UGYR_03495	COG3710	Transcriptional regulator
UGYR_03500	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UGYR_03505	COG0506	proline dehydrogenase activity
UGYR_03505	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
UGYR_03505	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
UGYR_03525	COG2515	1-aminocyclopropane-1-carboxylate deaminase
UGYR_03535	COG1191	sigma factor activity
UGYR_03575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
UGYR_03580	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UGYR_03595	COG1677	Flagellar hook-basal body complex protein FliE
UGYR_03605	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
UGYR_03615	COG1157	protein secretion by the type III secretion system
UGYR_03620	COG2882	bacterial-type flagellum organization
UGYR_03630	COG1580	Controls the rotational direction of flagella during chemotaxis
UGYR_03670	COG1256	bacterial-type flagellum assembly
UGYR_03690	COG4786	Flagellar basal body rod
UGYR_03700	COG1749	Flagellar hook protein flgE
UGYR_03705	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
UGYR_03710	COG1558	bacterial-type flagellum-dependent cell motility
UGYR_03715	COG1815	bacterial-type flagellum-dependent cell motility
UGYR_03725	COG2747	anti-sigma28 factor FlgM
UGYR_03730	COG3418	PFAM FlgN family protein
UGYR_03745	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UGYR_03750	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
UGYR_03760	COG2197	response regulator
UGYR_03780	COG3188	usher protein
UGYR_03785	COG3121	Chaperone
UGYR_03795	COG3539	Fimbrial protein
UGYR_03825	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
UGYR_03830	COG0745	RESPONSE REGULATOR receiver
UGYR_03840	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
UGYR_03845	COG0840	transmembrane signaling receptor activity
UGYR_03850	COG0840	transmembrane signaling receptor activity
UGYR_03855	COG0835	chemotaxis
UGYR_03860	COG2198	Histidine kinase
UGYR_03860	COG0643	Histidine kinase
UGYR_03865	COG1360	Flagellar Motor Protein
UGYR_03890	COG0589	response to stress
UGYR_03895	COG1285	pathogenesis
UGYR_03900	COG0840	transmembrane signaling receptor activity
UGYR_03910	COG1278	Cold shock
UGYR_03920	COG1609	Transcriptional regulator
UGYR_03930	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_03930	COG3321	synthase
UGYR_03930	COG0604	alcohol dehydrogenase
UGYR_03975	COG0471	metal ion transport
UGYR_03990	COG3051	citrate lyase alpha subunit
UGYR_03995	COG2301	Belongs to the HpcH HpaI aldolase family
UGYR_04000	COG3052	prosthetic group binding
UGYR_04005	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
UGYR_04010	COG3290	protein histidine kinase activity
UGYR_04015	COG4565	transcriptional regulatory protein
UGYR_04030	COG2271	Major facilitator Superfamily
UGYR_04035	COG1840	ABC-type Fe3 transport system, periplasmic component
UGYR_04045	COG3842	ATPase activity
UGYR_04065	COG1289	transmembrane transporter activity
UGYR_04075	COG2925	Exonuclease
UGYR_04080	COG0531	amino acid
UGYR_04085	COG4771	TonB-dependent receptor
UGYR_04095	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UGYR_04105	COG0833	amino acid
UGYR_04110	COG0583	DNA-binding transcription factor activity
UGYR_04125	COG2855	membrane
UGYR_04130	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
UGYR_04135	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
UGYR_04135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
UGYR_04135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
UGYR_04140	COG1105	Belongs to the carbohydrate kinase PfkB family
UGYR_04155	COG3005	denitrification pathway
UGYR_04160	COG0243	molybdopterin cofactor binding
UGYR_04175	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
UGYR_04180	COG1312	Catalyzes the dehydration of D-mannonate
UGYR_04185	COG0246	Mannitol dehydrogenase
UGYR_04195	COG0523	cobalamin synthesis protein
UGYR_04200	COG0671	phosphoesterase, PA-phosphatase related
UGYR_04205	COG0791	NLP P60 protein
UGYR_04210	COG2200	EAL domain
UGYR_04215	COG4166	transmembrane transport
UGYR_04220	COG4174	ABC transporter (Permease)
UGYR_04225	COG4239	(ABC) transporter, permease
UGYR_04230	COG4172	Belongs to the ABC transporter superfamily
UGYR_04240	COG2814	Major facilitator Superfamily
UGYR_04245	COG1187	pseudouridine synthase activity
UGYR_04265	COG3082	Protein of unknown function (DUF1414)
UGYR_04275	COG3083	sulfuric ester hydrolase activity
UGYR_04280	COG3083	sulfuric ester hydrolase activity
UGYR_04295	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
UGYR_04315	COG3778	Protein conserved in bacteria
UGYR_04320	COG3299	homolog of phage Mu protein gp47
UGYR_04365	COG4386	tail sheath protein
UGYR_04405	COG0740	serine-type endopeptidase activity
UGYR_04415	COG4626	Terminase
UGYR_04415	COG1802	Transcriptional regulator
UGYR_04430	COG3646	Phage regulatory protein
UGYR_04465	COG1403	HNH endonuclease
UGYR_04495	COG4626	Terminase
UGYR_04495	COG1802	Transcriptional regulator
UGYR_04545	COG5532	Uncharacterized conserved protein (DUF2303)
UGYR_04550	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
UGYR_04585	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
UGYR_04590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UGYR_04610	COG2223	nitrite transmembrane transporter activity
UGYR_04615	COG0642	Histidine kinase
UGYR_04615	COG2198	Histidine kinase
UGYR_04625	COG0784	Response regulator, receiver
UGYR_04625	COG2205	protein histidine kinase activity
UGYR_04635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UGYR_04640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UGYR_04650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UGYR_04660	COG4574	serine-type endopeptidase inhibitor activity
UGYR_04670	COG2246	polysaccharide biosynthetic process
UGYR_04685	COG0814	amino acid
UGYR_04710	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
UGYR_04715	COG0596	Alpha beta hydrolase
UGYR_04720	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
UGYR_04725	COG1169	isochorismate synthase
UGYR_04730	COG4575	ribosome binding
UGYR_04745	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_04750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
UGYR_04760	COG0839	Belongs to the complex I subunit 6 family
UGYR_04765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_04770	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
UGYR_04775	COG1034	ATP synthesis coupled electron transport
UGYR_04785	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
UGYR_04795	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_04800	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
UGYR_04805	COG0583	DNA-binding transcription factor activity
UGYR_04815	COG0436	Aminotransferase
UGYR_04820	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
UGYR_04825	COG0490	domain, Protein
UGYR_04825	COG0471	metal ion transport
UGYR_04835	COG3013	Belongs to the UPF0304 family
UGYR_04840	COG3092	negative regulation of chromosome organization
UGYR_04850	COG0857	belongs to the CobB CobQ family
UGYR_04850	COG0280	phosphate acetyltransferase
UGYR_04855	COG1609	Transcriptional regulator
UGYR_04870	COG3037	sugar-specific permease SgaT UlaA
UGYR_04875	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
UGYR_04880	COG0622	Phosphoesterase
UGYR_04890	COG0625	glutathione transferase activity
UGYR_04895	COG1090	epimerase
UGYR_04905	COG4160	amino acid transport
UGYR_04910	COG4215	(ABC) transporter
UGYR_04915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_04920	COG0163	prenyltransferase activity
UGYR_04925	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
UGYR_04930	COG1286	toxin biosynthetic process
UGYR_04935	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
UGYR_04940	COG0285	dihydrofolate synthase activity
UGYR_04950	COG0586	Pfam SNARE associated Golgi protein
UGYR_04960	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
UGYR_04985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
UGYR_04990	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UGYR_05030	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
UGYR_05045	COG3101	peptidyl-lysine hydroxylation
UGYR_05050	COG0730	response to heat
UGYR_05055	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
UGYR_05065	COG2890	protein-(glutamine-N5) methyltransferase activity
UGYR_05070	COG2840	Smr protein MutS2
UGYR_05075	COG2062	phosphohistidine phosphatase, SixA
UGYR_05080	COG1250	3-hydroxyacyl-CoA dehydrogenase
UGYR_05080	COG1024	Enoyl-CoA hydratase
UGYR_05085	COG0183	Belongs to the thiolase family
UGYR_05090	COG3691	Protein conserved in bacteria
UGYR_05105	COG3088	subunit of a heme lyase
UGYR_05105	COG4235	cytochrome complex assembly
UGYR_05110	COG3088	subunit of a heme lyase
UGYR_05110	COG4235	cytochrome complex assembly
UGYR_05115	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
UGYR_05120	COG1138	Cytochrome C-type biogenesis protein
UGYR_05125	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
UGYR_05130	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UGYR_05135	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UGYR_05140	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
UGYR_05160	COG2824	Alkylphosphonate utilization operon protein PhnA
UGYR_05165	COG2951	lytic endotransglycosylase activity
UGYR_05170	COG1598	PFAM Uncharacterised protein family UPF0150
UGYR_05175	COG3038	cytochrome b561
UGYR_05180	COG0436	Aminotransferase
UGYR_05190	COG3275	phosphorelay sensor kinase activity
UGYR_05195	COG3279	Response regulator of the LytR AlgR family
UGYR_05200	COG2223	nitrite transmembrane transporter activity
UGYR_05205	COG0837	glucose binding
UGYR_05225	COG1914	H( )-stimulated, divalent metal cation uptake system
UGYR_05230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
UGYR_05295	COG3530	Putative quorum-sensing-regulated virulence factor
UGYR_05300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
UGYR_05310	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
UGYR_05315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
UGYR_05320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_05330	COG2190	(PTS) system
UGYR_05335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
UGYR_05345	COG4208	sulfate ABC transporter
UGYR_05350	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
UGYR_05365	COG1737	Transcriptional regulator
UGYR_05370	COG2731	YhcH YjgK YiaL family protein
UGYR_05385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UGYR_05390	COG2837	iron assimilation
UGYR_05400	COG3111	PFAM Bacterial OB fold (BOF) protein
UGYR_05415	COG1671	Belongs to the UPF0178 family
UGYR_05420	COG0280	phosphate acetyltransferase
UGYR_05420	COG0281	malic enzyme
UGYR_05425	COG0494	nUDIX hydrolase
UGYR_05430	COG3005	denitrification pathway
UGYR_05435	COG3043	anaerobic respiration
UGYR_05440	COG0243	molybdopterin cofactor binding
UGYR_05445	COG3062	negative regulation of establishment of protein localization
UGYR_05450	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
UGYR_05450	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UGYR_05460	COG2197	response regulator
UGYR_05470	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UGYR_05480	COG1605	Chorismate mutase
UGYR_05485	COG1393	Belongs to the ArsC family
UGYR_05490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
UGYR_05495	COG1876	peptidase activity
UGYR_05505	COG0400	carboxylic ester hydrolase activity
UGYR_05525	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
UGYR_05530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
UGYR_05535	COG2716	regulation of RNA biosynthetic process
UGYR_05540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
UGYR_05545	COG0628	permease
UGYR_05550	COG4783	chaperone-mediated protein folding
UGYR_05555	COG1393	Belongs to the ArsC family
UGYR_05560	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
UGYR_05565	COG2233	PERMEase
UGYR_05570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
UGYR_05575	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
UGYR_05580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
UGYR_05585	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UGYR_05595	COG0581	inorganic phosphate transmembrane transporter activity
UGYR_05600	COG0573	inorganic phosphate transmembrane transporter activity
UGYR_05610	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
UGYR_05615	COG0248	Ppx GppA phosphatase
UGYR_05625	COG2239	Acts as a magnesium transporter
UGYR_05630	COG0443	Heat shock 70 kDa protein
UGYR_05640	COG3121	Chaperone
UGYR_05660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UGYR_05670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UGYR_05675	COG0477	Major facilitator Superfamily
UGYR_05680	COG2205	protein histidine kinase activity
UGYR_05685	COG0745	RESPONSE REGULATOR receiver
UGYR_05690	COG3422	double-strand break repair
UGYR_05700	COG1597	lipid kinase activity
UGYR_05715	COG0351	phosphomethylpyrimidine kinase
UGYR_05800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
UGYR_05800	COG0519	Catalyzes the synthesis of GMP from XMP
UGYR_05805	COG0517	IMP dehydrogenase activity
UGYR_05805	COG0516	GMP reductase activity
UGYR_05810	COG1570	exodeoxyribonuclease VII activity
UGYR_05820	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UGYR_05825	COG2976	Protein conserved in bacteria
UGYR_05830	COG0124	histidyl-tRNA synthetase
UGYR_05865	COG4953	penicillin-binding protein 1C
UGYR_05870	COG2373	Large extracellular alpha-helical protein
UGYR_05885	COG2975	iron-sulfur cluster assembly
UGYR_05890	COG0633	Ferredoxin
UGYR_05895	COG0443	Heat shock 70 kDa protein
UGYR_05910	COG0822	iron-sulfur transferase activity
UGYR_05920	COG1959	2 iron, 2 sulfur cluster binding
UGYR_05925	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
UGYR_05935	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
UGYR_05940	COG3683	transport system, periplasmic component
UGYR_05945	COG3711	transcriptional antiterminator
UGYR_05950	COG2814	Major facilitator Superfamily
UGYR_05960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UGYR_05960	COG1017	nitric oxide dioxygenase activity
UGYR_05965	COG2188	Transcriptional regulator
UGYR_05975	COG3457	Alanine racemase
UGYR_05980	COG1735	metal-dependent hydrolase with the TIM-barrel fold
UGYR_05995	COG0347	Belongs to the P(II) protein family
UGYR_06000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UGYR_06000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
UGYR_06005	COG2204	response regulator
UGYR_06010	COG3170	Tfp pilus assembly protein FimV
UGYR_06015	COG2205	protein histidine kinase activity
UGYR_06035	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
UGYR_06040	COG0590	tRNA wobble adenosine to inosine editing
UGYR_06045	COG0560	Phosphoserine phosphatase
UGYR_06050	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_06050	COG1263	PTS System
UGYR_06060	COG1737	Transcriptional regulator
UGYR_06065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
UGYR_06075	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
UGYR_06085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
UGYR_06095	COG0681	Belongs to the peptidase S26 family
UGYR_06100	COG0481	GTPase activity
UGYR_06105	COG3086	response to oxidative stress
UGYR_06115	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
UGYR_06125	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
UGYR_06135	COG0513	Belongs to the DEAD box helicase family
UGYR_06150	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
UGYR_06160	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
UGYR_06165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
UGYR_06170	COG0497	DNA recombination
UGYR_06175	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UGYR_06185	COG2867	negative regulation of translational initiation
UGYR_06190	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
UGYR_06195	COG0582	viral genome integration into host DNA
UGYR_06205	COG2963	transposase activity
UGYR_06225	COG2856	Zn peptidase
UGYR_06235	COG3596	GTP binding
UGYR_06255	COG1204	response to ionizing radiation
UGYR_06265	COG0582	viral genome integration into host DNA
UGYR_06280	COG3121	Chaperone
UGYR_06300	COG0583	DNA-binding transcription factor activity
UGYR_06340	COG2963	transposase activity
UGYR_06350	COG1069	ribulokinase activity
UGYR_06360	COG1172	Belongs to the binding-protein-dependent transport system permease family
UGYR_06365	COG1129	ABC transporter
UGYR_06385	COG1620	l-lactate permease
UGYR_06390	COG1304	FMN binding
UGYR_06395	COG0579	oxidoreductase
UGYR_06400	COG1278	Cold shock
UGYR_06430	COG1780	Probably involved in ribonucleotide reductase function
UGYR_06435	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
UGYR_06445	COG4175	Glycine betaine
UGYR_06450	COG4176	ABC-type proline glycine betaine transport system permease component
UGYR_06455	COG2113	Glycine betaine
UGYR_06465	COG2814	Major facilitator Superfamily
UGYR_06470	COG1846	Transcriptional regulator
UGYR_06480	COG1566	PFAM secretion protein HlyD family protein
UGYR_06485	COG2814	Major facilitator Superfamily
UGYR_06490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UGYR_06495	COG3118	belongs to the thioredoxin family
UGYR_06505	COG0045	succinate-CoA ligase (ADP-forming) activity
UGYR_06505	COG1042	CoA-binding domain protein
UGYR_06505	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
UGYR_06510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
UGYR_06515	COG5544	Lipoprotein
UGYR_06540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
UGYR_06550	COG2011	ABC-type metal ion transport system permease component
UGYR_06555	COG1464	Belongs to the NlpA lipoprotein family
UGYR_06565	COG1720	tRNA m6t6A37 methyltransferase activity
UGYR_06570	COG0442	prolyl-tRNA aminoacylation
UGYR_06575	COG3015	lipoprotein NlpE involved in copper resistance
UGYR_06585	COG4681	YaeQ
UGYR_06595	COG4568	rho-dependent transcription termination
UGYR_06605	COG0037	tRNA processing
UGYR_06610	COG0346	lactoylglutathione lyase activity
UGYR_06625	COG0825	malonyl-CoA metabolic process
UGYR_06630	COG0587	DNA-directed DNA polymerase activity
UGYR_06635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
UGYR_06640	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UGYR_06655	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
UGYR_06660	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
UGYR_06670	COG0750	zinc metalloprotease
UGYR_06675	COG0575	Belongs to the CDS family
UGYR_06680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
UGYR_06695	COG0528	UMP kinase activity
UGYR_06700	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
UGYR_06710	COG0024	Methionine aminopeptidase
UGYR_06715	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
UGYR_06720	COG2171	N-acyltransferase activity
UGYR_06735	COG0564	pseudouridine synthase activity
UGYR_06740	COG3098	single-species biofilm formation
UGYR_06755	COG1611	Belongs to the LOG family
UGYR_06765	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
UGYR_06770	COG2363	Small membrane protein
UGYR_06775	COG0583	DNA-binding transcription factor activity
UGYR_06785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
UGYR_06790	COG2166	iron-sulfur cluster assembly
UGYR_06795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
UGYR_06800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
UGYR_06820	COG0860	N-Acetylmuramoyl-L-alanine amidase
UGYR_06825	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
UGYR_06825	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
UGYR_06830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
UGYR_06835	COG1074	ATP-dependent DNA helicase activity
UGYR_06840	COG1025	Belongs to the peptidase M16 family
UGYR_06845	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
UGYR_06850	COG4967	type IV pilus modification protein PilV
UGYR_06880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
UGYR_06885	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
UGYR_06895	COG3066	DNA modification
UGYR_06900	COG0861	Integral membrane protein TerC family
UGYR_06905	COG0667	Aldo Keto reductase
UGYR_06910	COG0477	Major facilitator Superfamily
UGYR_06915	COG0318	PFAM AMP-dependent synthetase and ligase
UGYR_06915	COG0204	Acyl-transferase
UGYR_06920	COG1609	Transcriptional regulator
UGYR_06925	COG0019	diaminopimelate decarboxylase activity
UGYR_06930	COG0583	DNA-binding transcription factor activity
UGYR_06935	COG0583	DNA-binding transcription factor activity
UGYR_06975	COG4795	General secretion pathway protein
UGYR_06990	COG2165	general secretion pathway protein
UGYR_07000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UGYR_07030	COG1127	ABC transporter
UGYR_07035	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
UGYR_07045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
UGYR_07050	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
UGYR_07055	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
UGYR_07060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UGYR_07065	COG4974	Belongs to the 'phage' integrase family
UGYR_07070	COG0716	FMN binding
UGYR_07080	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
UGYR_07090	COG1272	protein, Hemolysin III
UGYR_07105	COG0404	The glycine cleavage system catalyzes the degradation of glycine
UGYR_07110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UGYR_07115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UGYR_07120	COG0006	proline dipeptidase activity
UGYR_07130	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
UGYR_07135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
UGYR_07140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
UGYR_07145	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
UGYR_07160	COG1279	arginine transmembrane transporter activity
UGYR_07170	COG0191	fructose-bisphosphate aldolase activity
UGYR_07175	COG0126	phosphoglycerate kinase activity
UGYR_07180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
UGYR_07185	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
UGYR_07195	COG1166	arginine decarboxylase activity
UGYR_07200	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
UGYR_07215	COG0640	Transcriptional regulator
UGYR_07220	COG3091	SprT-like family
UGYR_07225	COG2356	endonuclease I
UGYR_07230	COG1385	rRNA (uridine-N3-)-methyltransferase activity
UGYR_07235	COG0189	ligase activity
UGYR_07240	COG1678	Uncharacterized ACR, COG1678
UGYR_07245	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
UGYR_07250	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UGYR_07260	COG2805	Type II/IV secretion system protein
UGYR_07265	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
UGYR_07270	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
UGYR_07275	COG0762	integral membrane protein
UGYR_07280	COG1872	DUF167
UGYR_07285	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
UGYR_07290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UGYR_07300	COG2066	Belongs to the glutaminase family
UGYR_07305	COG3171	Protein conserved in bacteria
UGYR_07315	COG1194	a g-specific adenine glycosylase
UGYR_07320	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
UGYR_07325	COG0741	lytic transglycosylase activity
UGYR_07350	COG3730	PTS system glucitol sorbitol-specific
UGYR_07355	COG3732	PTS system glucitol sorbitol-specific
UGYR_07360	COG3731	PTS system glucitol sorbitol-specific IIA component
UGYR_07365	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_07370	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_07375	COG1349	DNA-binding transcription factor activity
UGYR_07385	COG1105	Belongs to the carbohydrate kinase PfkB family
UGYR_07390	COG1882	Formate acetyltransferase
UGYR_07395	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
UGYR_07400	COG0814	amino acid
UGYR_07415	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_07420	COG3433	isochorismatase activity
UGYR_07420	COG1535	isochorismatase
UGYR_07425	COG1021	2,3-dihydroxybenzoate-AMP ligase
UGYR_07430	COG1169	isochorismate synthase
UGYR_07435	COG4592	Periplasmic binding protein
UGYR_07445	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UGYR_07450	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
UGYR_07455	COG1120	ATPase activity
UGYR_07465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
UGYR_07470	COG3251	PFAM MbtH domain protein
UGYR_07480	COG4774	siderophore transport
UGYR_07485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
UGYR_07510	COG4964	Belongs to the GSP D family
UGYR_07560	COG0848	biopolymer transport protein
UGYR_07565	COG0811	peptide transport
UGYR_07570	COG0626	cystathionine gamma-synthase activity
UGYR_07575	COG0586	Pfam SNARE associated Golgi protein
UGYR_07580	COG2207	Transcriptional regulator
UGYR_07585	COG1979	alcohol dehydrogenase
UGYR_07590	COG0656	L-ascorbic acid biosynthetic process
UGYR_07600	COG2132	Multicopper oxidase
UGYR_07605	COG0204	Acyl-transferase
UGYR_07610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
UGYR_07615	COG2249	NAD(P)H dehydrogenase (quinone) activity
UGYR_07620	COG0583	DNA-binding transcription factor activity
UGYR_07625	COG0187	DNA topoisomerase II activity
UGYR_07630	COG3150	esterase
UGYR_07640	COG3151	Protein conserved in bacteria
UGYR_07645	COG0494	nUDIX hydrolase
UGYR_07650	COG1538	Outer membrane efflux protein
UGYR_07655	COG5463	Belongs to the UPF0441 family
UGYR_07660	COG0754	glutathionylspermidine amidase activity
UGYR_07665	COG3384	dioxygenase
UGYR_07670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
UGYR_07680	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
UGYR_07680	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
UGYR_07690	COG3025	triphosphatase activity
UGYR_07695	COG4991	sh3 domain protein
UGYR_07700	COG0617	tRNA 3'-terminal CCA addition
UGYR_07705	COG1968	undecaprenyl-diphosphatase activity
UGYR_07710	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
UGYR_07715	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
UGYR_07720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
UGYR_07730	COG0358	DNA primase activity
UGYR_07735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UGYR_07755	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_07770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
UGYR_07785	COG3210	domain, Protein
UGYR_07825	COG3210	domain, Protein
UGYR_07830	COG2831	hemolysin activation secretion protein
UGYR_07835	COG1902	pentaerythritol trinitrate reductase activity
UGYR_07835	COG0446	pyridine nucleotide-disulphide oxidoreductase
UGYR_07850	COG1451	nucleotide metabolic process
UGYR_07855	COG0673	inositol 2-dehydrogenase activity
UGYR_07860	COG0861	Integral membrane protein TerC family
UGYR_07865	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
UGYR_07875	COG2721	sulfolactate sulfo-lyase activity
UGYR_07880	COG0246	Mannitol dehydrogenase
UGYR_07890	COG2271	Major facilitator Superfamily
UGYR_07905	COG0586	Pfam SNARE associated Golgi protein
UGYR_07920	COG4575	ribosome binding
UGYR_07925	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
UGYR_07935	COG2259	Doxx family
UGYR_07940	COG0583	DNA-binding transcription factor activity
UGYR_07945	COG1741	Belongs to the pirin family
UGYR_07950	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
UGYR_07965	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
UGYR_07970	COG2823	Periplasmic or secreted lipoprotein
UGYR_07975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UGYR_07980	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
UGYR_07985	COG0784	Response regulator, receiver
UGYR_07985	COG5002	protein histidine kinase activity
UGYR_07985	COG2198	Histidine kinase
UGYR_07990	COG1242	4 iron, 4 sulfur cluster binding
UGYR_07995	COG0070	glutamate synthase
UGYR_07995	COG0069	glutamate synthase activity
UGYR_07995	COG0067	glutamate synthase
UGYR_08000	COG0493	'glutamate synthase
UGYR_08010	COG2969	positive regulation of protein catabolic process
UGYR_08015	COG0625	glutathione transferase activity
UGYR_08020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
UGYR_08025	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
UGYR_08030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
UGYR_08035	COG3105	Protein conserved in bacteria
UGYR_08040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UGYR_08050	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
UGYR_08055	COG5007	Belongs to the BolA IbaG family
UGYR_08060	COG3113	response to antibiotic
UGYR_08065	COG2854	intermembrane phospholipid transfer
UGYR_08070	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
UGYR_08075	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
UGYR_08080	COG1127	ABC transporter
UGYR_08085	COG0530	calcium, potassium:sodium antiporter activity
UGYR_08090	COG0517	IMP dehydrogenase activity
UGYR_08090	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
UGYR_08095	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
UGYR_08100	COG3117	lipopolysaccharide transmembrane transporter activity
UGYR_08105	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
UGYR_08110	COG1137	ATPase activity
UGYR_08115	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
UGYR_08125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_08135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_08140	COG0540	Belongs to the ATCase OTCase family
UGYR_08145	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
UGYR_08155	COG0366	Alpha amylase catalytic
UGYR_08160	COG1263	PTS System
UGYR_08160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_08170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
UGYR_08185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UGYR_08190	COG3783	Cytochrome b(562)
UGYR_08195	COG0312	modulator of DNA gyrase
UGYR_08200	COG3028	Belongs to the UPF0307 family
UGYR_08205	COG2732	(Barnase) inhibitor
UGYR_08210	COG4290	ribonuclease
UGYR_08220	COG1289	transmembrane transporter activity
UGYR_08225	COG1566	PFAM secretion protein HlyD family protein
UGYR_08235	COG0583	DNA-binding transcription factor activity
UGYR_08240	COG0312	modulator of DNA gyrase
UGYR_08245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
UGYR_08250	COG3164	Protein of unknown function
UGYR_08255	COG1530	ribonuclease E activity
UGYR_08265	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
UGYR_08270	COG1792	Involved in formation and maintenance of cell shape
UGYR_08275	COG1077	Cell shape determining protein MreB Mrl
UGYR_08280	COG2200	EAL domain
UGYR_08280	COG2199	diguanylate cyclase activity
UGYR_08285	COG0604	alcohol dehydrogenase
UGYR_08290	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
UGYR_08295	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
UGYR_08305	COG0511	ligase activity, forming carbon-carbon bonds
UGYR_08310	COG0439	Biotin carboxylase
UGYR_08315	COG3924	membrane
UGYR_08320	COG4145	pantothenate transmembrane transporter activity
UGYR_08325	COG2264	protein methyltransferase activity
UGYR_08330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
UGYR_08335	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
UGYR_08345	COG1560	Kdo2-lipid A biosynthetic process
UGYR_08355	COG1346	cytolysis
UGYR_08360	COG1380	Effector of murein hydrolase LrgA
UGYR_08365	COG0583	DNA-binding transcription factor activity
UGYR_08370	COG0025	NhaP-type Na H and K H
UGYR_08375	COG2252	PERMEase
UGYR_08390	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
UGYR_08395	COG2315	Protein conserved in bacteria
UGYR_08400	COG1448	Aminotransferase
UGYR_08405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
UGYR_08410	COG0305	Participates in initiation and elongation during chromosome replication
UGYR_08415	COG0604	alcohol dehydrogenase
UGYR_08425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
UGYR_08430	COG0735	belongs to the Fur family
UGYR_08435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
UGYR_08440	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
UGYR_08445	COG2937	Belongs to the GPAT DAPAT family
UGYR_08465	COG4580	involved in the transport of maltose and maltodextrins
UGYR_08480	COG2182	Extracellular solute-binding protein
UGYR_08485	COG1175	transmembrane transport
UGYR_08490	COG3833	ABC-type maltose transport systems, permease component
UGYR_08495	COG3223	Belongs to the PsiE family
UGYR_08505	COG0527	aspartate kinase activity
UGYR_08520	COG3328	transposase activity
UGYR_08545	COG1222	aaa ATPase
UGYR_08620	COG0583	DNA-binding transcription factor activity
UGYR_08655	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
UGYR_08695	COG0138	bifunctional purine biosynthesis protein purh
UGYR_08700	COG0151	Belongs to the GarS family
UGYR_08710	COG0776	regulation of translation
UGYR_08715	COG3068	Protein conserved in bacteria
UGYR_08720	COG1515	deoxyribonuclease V activity
UGYR_08725	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
UGYR_08730	COG2816	NAD+ diphosphatase activity
UGYR_08735	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
UGYR_08740	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
UGYR_08750	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
UGYR_08755	COG2104	thiamine diphosphate biosynthetic process
UGYR_08760	COG2022	thiamine diphosphate biosynthetic process
UGYR_08770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
UGYR_08775	COG0085	RNA polymerase activity
UGYR_08780	COG0222	ribosome binding
UGYR_08785	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
UGYR_08795	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
UGYR_08800	COG0250	Participates in transcription elongation, termination and antitermination
UGYR_08805	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
UGYR_08845	COG0812	UDP-N-acetylmuramate dehydrogenase activity
UGYR_08875	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
UGYR_08880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
UGYR_08885	COG1739	Uncharacterized protein family UPF0029
UGYR_08895	COG1250	3-hydroxyacyl-CoA dehydrogenase
UGYR_08895	COG1024	Enoyl-CoA hydratase
UGYR_08905	COG0543	2 iron, 2 sulfur cluster binding
UGYR_08920	COG0250	Participates in transcription elongation, termination and antitermination
UGYR_08935	COG0805	protein transport
UGYR_08945	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
UGYR_08950	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
UGYR_08955	COG3165	ubiquinone biosynthetic process from chorismate
UGYR_08960	COG2226	methyltransferase
UGYR_08965	COG1322	Protein conserved in bacteria
UGYR_08970	COG0586	Pfam SNARE associated Golgi protein
UGYR_08975	COG1966	Carbon starvation protein
UGYR_08990	COG0412	Dienelactone hydrolase
UGYR_08995	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
UGYR_09000	COG0583	DNA-binding transcription factor activity
UGYR_09015	COG0584	glycerophosphoryl diester phosphodiesterase
UGYR_09025	COG0395	ABC-type sugar transport system, permease component
UGYR_09030	COG1175	transmembrane transport
UGYR_09035	COG1653	transport
UGYR_09070	COG0410	ABC transporter
UGYR_09075	COG0411	ABC transporter
UGYR_09080	COG4177	L-phenylalanine transmembrane transporter activity
UGYR_09085	COG0559	Belongs to the binding-protein-dependent transport system permease family
UGYR_09100	COG1929	Belongs to the glycerate kinase type-1 family
UGYR_09105	COG2610	gluconate transmembrane transporter activity
UGYR_09110	COG3835	regulator
UGYR_09120	COG2177	Part of the ABC transporter FtsEX involved in
UGYR_09125	COG2884	Cell division ATP-binding protein ftsE
UGYR_09130	COG0552	protein localization to endoplasmic reticulum
UGYR_09130	COG0552	protein localization to endoplasmic reticulum
UGYR_09135	COG0742	ribosomal rna small subunit methyltransferase
UGYR_09140	COG3776	membrane
UGYR_09155	COG3714	YhhN family
UGYR_09170	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
UGYR_09180	COG0247	lactate metabolic process
UGYR_09190	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
UGYR_09200	COG2271	Major facilitator Superfamily
UGYR_09205	COG0584	glycerophosphoryl diester phosphodiesterase
UGYR_09210	COG0561	phosphatase activity
UGYR_09215	COG2267	carboxylic ester hydrolase activity
UGYR_09220	COG1280	lysine exporter protein (LysE YggA)
UGYR_09225	COG0514	ATP-dependent DNA helicase (RecQ)
UGYR_09230	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
UGYR_09235	COG2050	protein possibly involved in aromatic compounds catabolism
UGYR_09245	COG0598	Magnesium transport protein CorA
UGYR_09255	COG5564	TIM-barrel signal transduction protein
UGYR_09260	COG5441	Belongs to the UPF0261 family
UGYR_09270	COG0210	DNA helicase
UGYR_09275	COG1011	Hydrolase
UGYR_09280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
UGYR_09285	COG3159	Protein conserved in bacteria
UGYR_09290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
UGYR_09295	COG5567	small periplasmic lipoprotein
UGYR_09305	COG3072	Adenylate cyclase
UGYR_09310	COG0181	hydroxymethylbilane synthase activity
UGYR_09315	COG1587	Uroporphyrinogen-III synthase
UGYR_09320	COG2959	enzyme of heme biosynthesis
UGYR_09325	COG3071	HemY protein
UGYR_09355	COG1113	amino acid transport
UGYR_09375	COG2244	polysaccharide biosynthetic process
UGYR_09380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
UGYR_09385	COG0456	acetyltransferase
UGYR_09390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
UGYR_09395	COG1088	dTDP-glucose 4,6-dehydratase activity
UGYR_09400	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
UGYR_09405	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
UGYR_09410	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
UGYR_09415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
UGYR_09420	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
UGYR_09425	COG3118	belongs to the thioredoxin family
UGYR_09435	COG0248	Ppx GppA phosphatase
UGYR_09445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UGYR_09455	COG0583	DNA-binding transcription factor activity
UGYR_09460	COG3397	chitin binding
UGYR_09470	COG0129	dihydroxy-acid dehydratase activity
UGYR_09475	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
UGYR_09480	COG3978	acetolactate synthase activity
UGYR_09495	COG3085	chromosome segregation
UGYR_09500	COG0583	DNA-binding transcription factor activity
UGYR_09565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UGYR_09575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
UGYR_09575	COG0678	peroxiredoxin activity
UGYR_09580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UGYR_09615	COG1629	transport
UGYR_09620	COG0165	Argininosuccinate lyase
UGYR_09625	COG0137	argininosuccinate synthase activity
UGYR_09630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
UGYR_09635	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
UGYR_09670	COG0460	homoserine dehydrogenase
UGYR_09670	COG0527	aspartate kinase activity
UGYR_09675	COG0626	cystathionine gamma-synthase activity
UGYR_09680	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
UGYR_09690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
UGYR_09695	COG1609	Transcriptional regulator
UGYR_09700	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
UGYR_09705	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
UGYR_09710	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
UGYR_09715	COG1575	Belongs to the MenA family. Type 1 subfamily
UGYR_09720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
UGYR_09725	COG3074	FtsZ-dependent cytokinesis
UGYR_09730	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
UGYR_09735	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
UGYR_09740	COG1494	fructose-1,6-bisphosphatase
UGYR_09745	COG2814	Major facilitator Superfamily
UGYR_09755	COG3152	Membrane
UGYR_09770	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
UGYR_09780	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
UGYR_09785	COG3678	ATP-independent chaperone mediated protein folding
UGYR_09790	COG0745	RESPONSE REGULATOR receiver
UGYR_09795	COG2205	protein histidine kinase activity
UGYR_09800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
UGYR_09805	COG1045	serine acetyltransferase
UGYR_09810	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
UGYR_09815	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
UGYR_09820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
UGYR_09825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
UGYR_09830	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
UGYR_09835	COG4942	peptidase
UGYR_09840	COG2861	carbohydrate metabolic process
UGYR_09855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UGYR_09860	COG0859	PFAM glycosyl transferase family 9
UGYR_09865	COG0859	PFAM glycosyl transferase family 9
UGYR_09870	COG1519	Transferase
UGYR_09890	COG0267	Belongs to the bacterial ribosomal protein bL33 family
UGYR_09895	COG0227	Belongs to the bacterial ribosomal protein bL28 family
UGYR_09900	COG2003	Belongs to the UPF0758 family
UGYR_09905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
UGYR_09910	COG0756	dUTP diphosphatase activity
UGYR_09915	COG1309	transcriptional regulator
UGYR_09920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
UGYR_09925	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
UGYR_09930	COG1561	YicC-like family, N-terminal region
UGYR_09945	COG5001	Diguanylate cyclase
UGYR_09965	COG1024	Enoyl-CoA hydratase
UGYR_09970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
UGYR_09980	COG2860	membrane
UGYR_09985	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
UGYR_09995	COG1758	RNA polymerase activity
UGYR_10000	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
UGYR_10005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UGYR_10010	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
UGYR_10015	COG0786	glutamate:sodium symporter activity
UGYR_10020	COG2233	PERMEase
UGYR_10025	COG2982	Protein involved in outer membrane biogenesis
UGYR_10030	COG0456	acetyltransferase
UGYR_10045	COG1011	Hydrolase
UGYR_10055	COG0174	glutamine synthetase
UGYR_10060	COG3852	Histidine kinase
UGYR_10070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
UGYR_10080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
UGYR_10085	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UGYR_10085	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
UGYR_10090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
UGYR_10095	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
UGYR_10100	COG3084	Protein conserved in bacteria
UGYR_10110	COG1763	Mo-molybdopterin cofactor biosynthetic process
UGYR_10135	COG2186	Transcriptional regulator
UGYR_10140	COG1609	Transcriptional regulator
UGYR_10145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UGYR_10150	COG1879	ABC-type sugar transport system periplasmic component
UGYR_10155	COG1172	Belongs to the binding-protein-dependent transport system permease family
UGYR_10160	COG1129	ABC transporter
UGYR_10165	COG1869	D-ribose catabolic process
UGYR_10170	COG3158	transport of potassium into the cell
UGYR_10175	COG0714	Associated with various cellular activities
UGYR_10180	COG2425	protein containing a von Willebrand factor type A (vWA) domain
UGYR_10190	COG2502	aspartate--ammonia ligase
UGYR_10195	COG1522	sequence-specific DNA binding
UGYR_10200	COG0716	FMN binding
UGYR_10205	COG0445	tRNA wobble uridine modification
UGYR_10210	COG0357	Ribosomal RNA small subunit methyltransferase G
UGYR_10215	COG3312	ion transport
UGYR_10220	COG0356	it plays a direct role in the translocation of protons across the membrane
UGYR_10230	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
UGYR_10240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
UGYR_10245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
UGYR_10255	COG0355	proton-transporting ATP synthase activity, rotational mechanism
UGYR_10265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
UGYR_10270	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
UGYR_10275	COG0573	inorganic phosphate transmembrane transporter activity
UGYR_10280	COG0581	inorganic phosphate transmembrane transporter activity
UGYR_10290	COG0704	Plays a role in the regulation of phosphate uptake
UGYR_10295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_10300	COG0765	amino acid transport
UGYR_10305	COG0765	amino acid transport
UGYR_10310	COG2252	PERMEase
UGYR_10315	COG0840	transmembrane signaling receptor activity
UGYR_10325	COG3121	Chaperone
UGYR_10340	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
UGYR_10345	COG0706	membrane insertase activity
UGYR_10355	COG0594	ribonuclease P activity
UGYR_10360	COG0230	Belongs to the bacterial ribosomal protein bL34 family
UGYR_10370	COG0592	DNA-directed DNA polymerase activity
UGYR_10380	COG0187	DNA topoisomerase II activity
UGYR_10385	COG0561	phosphatase activity
UGYR_10390	COG0823	Involved in the tonB-independent uptake of proteins
UGYR_10395	COG5645	(Lipo)protein
UGYR_10410	COG2985	domain, Protein
UGYR_10410	COG0569	domain protein
UGYR_10415	COG3977	Valine--pyruvate aminotransferase
UGYR_10420	COG2885	chlorophyll binding
UGYR_10440	COG2818	Glycosylase
UGYR_10490	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_10490	COG2213	PTS system mannitol-specific
UGYR_10500	COG3722	fumarate hydratase activity
UGYR_10510	COG2258	MOSC domain
UGYR_10515	COG0840	transmembrane signaling receptor activity
UGYR_10520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
UGYR_10530	COG0243	molybdopterin cofactor binding
UGYR_10530	COG3383	formate dehydrogenase (NAD+) activity
UGYR_10535	COG0243	molybdopterin cofactor binding
UGYR_10535	COG3383	formate dehydrogenase (NAD+) activity
UGYR_10540	COG0437	4 iron, 4 sulfur cluster binding
UGYR_10545	COG2864	formate dehydrogenase
UGYR_10555	COG1921	L-seryl-tRNASec selenium transferase activity
UGYR_10560	COG3276	selenocysteine insertion sequence binding
UGYR_10565	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
UGYR_10575	COG3274	enterobacterial common antigen metabolic process
UGYR_10580	COG2801	Transposase and inactivated derivatives
UGYR_10605	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
UGYR_10610	COG2986	histidine ammonia-lyase
UGYR_10630	COG2194	sulfuric ester hydrolase activity
UGYR_10635	COG2197	response regulator
UGYR_10640	COG3851	Histidine kinase
UGYR_10645	COG2271	Major facilitator Superfamily
UGYR_10655	COG0747	negative chemotaxis
UGYR_10660	COG0601	transmembrane transport
UGYR_10665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
UGYR_10670	COG0444	Belongs to the ABC transporter superfamily
UGYR_10675	COG4608	Belongs to the ABC transporter superfamily
UGYR_10680	COG2194	sulfuric ester hydrolase activity
UGYR_10705	COG1215	transferase activity, transferring glycosyl groups
UGYR_10710	COG1215	transferase activity, transferring glycosyl groups
UGYR_10715	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
UGYR_10720	COG3118	belongs to the thioredoxin family
UGYR_10720	COG0457	Tetratricopeptide repeat
UGYR_10725	COG2199	diguanylate cyclase activity
UGYR_10725	COG2200	EAL domain
UGYR_10730	COG1301	dicarboxylic acid transport
UGYR_10735	COG0612	Peptidase, M16
UGYR_10740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UGYR_10745	COG1942	4-Oxalocrotonate Tautomerase
UGYR_10750	COG2200	EAL domain
UGYR_10755	COG2134	cdp-diacylglycerol pyrophosphatase
UGYR_10760	COG1295	ribonuclease BN
UGYR_10770	COG1301	dicarboxylic acid transport
UGYR_10775	COG0626	cystathionine gamma-synthase activity
UGYR_10780	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UGYR_10785	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
UGYR_10790	COG0339	signal peptide processing
UGYR_10795	COG0742	ribosomal rna small subunit methyltransferase
UGYR_10805	COG0589	response to stress
UGYR_10815	COG0306	phosphate transporter
UGYR_10820	COG2081	HI0933 family
UGYR_10830	COG1247	-acetyltransferase
UGYR_10835	COG1741	Belongs to the pirin family
UGYR_10840	COG1609	Transcriptional regulator
UGYR_10845	COG2610	gluconate transmembrane transporter activity
UGYR_10850	COG3265	gluconokinase activity
UGYR_10855	COG2095	MarC family integral membrane protein
UGYR_10860	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
UGYR_10865	COG3275	phosphorelay sensor kinase activity
UGYR_10870	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
UGYR_10875	COG1523	belongs to the glycosyl hydrolase 13 family
UGYR_10880	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
UGYR_10885	COG0297	glycogen (starch) synthase activity
UGYR_10890	COG0058	SHG alpha-glucan phosphorylase activity
UGYR_10895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
UGYR_10900	COG1349	DNA-binding transcription factor activity
UGYR_10905	COG0705	Rhomboid family
UGYR_10915	COG2909	trisaccharide binding
UGYR_10920	COG0058	SHG alpha-glucan phosphorylase activity
UGYR_10925	COG1640	4-alpha-glucanotransferase
UGYR_10935	COG1040	competence protein
UGYR_10940	COG0596	Alpha beta hydrolase
UGYR_10960	COG1918	ferrous iron import across plasma membrane
UGYR_10965	COG2183	response to ionizing radiation
UGYR_10990	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UGYR_10995	COG0745	RESPONSE REGULATOR receiver
UGYR_11005	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
UGYR_11015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
UGYR_11020	COG1011	Hydrolase
UGYR_11030	COG0494	nUDIX hydrolase
UGYR_11035	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
UGYR_11060	COG4796	Type ii and iii secretion system protein
UGYR_11065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
UGYR_11085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
UGYR_11095	COG0180	Tryptophanyl-tRNA synthetase
UGYR_11110	COG2146	nitrite reductase [NAD(P)H] activity
UGYR_11115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
UGYR_11120	COG0402	S-adenosylhomocysteine deaminase activity
UGYR_11125	COG0738	Major facilitator superfamily
UGYR_11140	COG1609	Transcriptional regulator
UGYR_11145	COG1486	melibiose metabolic process
UGYR_11155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UGYR_11170	COG1289	transmembrane transporter activity
UGYR_11175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
UGYR_11180	COG1765	OsmC-like protein
UGYR_11205	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
UGYR_11210	COG3954	Phosphoribulokinase
UGYR_11220	COG0429	hydrolase of the alpha beta-hydrolase fold
UGYR_11230	COG0859	PFAM glycosyl transferase family 9
UGYR_11235	COG1216	Glycosyl transferase, family 2
UGYR_11240	COG0488	(ABC) transporter
UGYR_11245	COG2249	NAD(P)H dehydrogenase (quinone) activity
UGYR_11255	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
UGYR_11260	COG1047	Peptidyl-prolyl cis-trans
UGYR_11270	COG0545	Peptidyl-prolyl cis-trans isomerase
UGYR_11275	COG2964	Protein conserved in bacteria
UGYR_11285	COG2923	Belongs to the DsrF TusC family
UGYR_11290	COG2168	tRNA wobble position uridine thiolation
UGYR_11295	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
UGYR_11300	COG0049	tRNA binding
UGYR_11310	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
UGYR_11320	COG0051	transcription antitermination factor activity, RNA binding
UGYR_11325	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
UGYR_11335	COG0089	rRNA binding
UGYR_11340	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
UGYR_11345	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
UGYR_11350	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
UGYR_11355	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
UGYR_11360	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
UGYR_11365	COG0255	Belongs to the universal ribosomal protein uL29 family
UGYR_11370	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
UGYR_11375	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
UGYR_11385	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
UGYR_11410	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
UGYR_11415	COG1841	ribosomal large subunit assembly
UGYR_11420	COG0200	Binds to the 23S rRNA
UGYR_11425	COG0201	protein transport
UGYR_11430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
UGYR_11435	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
UGYR_11445	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
UGYR_11455	COG0203	ribosomal protein L17
UGYR_11460	COG0789	Transcriptional regulator
UGYR_11465	COG3036	rescue of stalled ribosome
UGYR_11470	COG1970	mechanosensitive ion channel activity
UGYR_11475	COG0569	domain protein
UGYR_11480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
UGYR_11480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
UGYR_11485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
UGYR_11490	COG0242	peptide deformylase activity
UGYR_11495	COG0758	DNA mediated transformation
UGYR_11500	COG2922	Belongs to the Smg family
UGYR_11505	COG0009	L-threonylcarbamoyladenylate synthase
UGYR_11515	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
UGYR_11545	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
UGYR_11550	COG3162	membrane
UGYR_11555	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
UGYR_11560	COG1301	dicarboxylic acid transport
UGYR_11570	COG1309	transcriptional regulator
UGYR_11575	COG4232	protein-disulfide reductase activity
UGYR_11585	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
UGYR_11615	COG1509	lysine 2,3-aminomutase activity
UGYR_11625	COG3397	chitin binding
UGYR_11645	COG3188	usher protein
UGYR_11655	COG2076	Multidrug Resistance protein
UGYR_11665	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
UGYR_11670	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
UGYR_11675	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
UGYR_11680	COG1053	succinate dehydrogenase
UGYR_11685	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
UGYR_11690	COG1511	domain protein
UGYR_11690	COG3264	Mechanosensitive ion channel
UGYR_11695	COG0688	phosphatidylethanolamine metabolic process
UGYR_11700	COG1162	GTPase activity
UGYR_11705	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
UGYR_11725	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
UGYR_11730	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
UGYR_11730	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
UGYR_11735	COG0802	atpase or kinase
UGYR_11740	COG0860	N-Acetylmuramoyl-L-alanine amidase
UGYR_11750	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
UGYR_11760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
UGYR_11765	COG0330	HflC and HflK could
UGYR_11770	COG0330	HflC and HflK could
UGYR_11775	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
UGYR_11780	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
UGYR_11785	COG1959	2 iron, 2 sulfur cluster binding
UGYR_11790	COG0557	exoribonuclease II activity
UGYR_11795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
UGYR_11815	COG3121	Chaperone
UGYR_11820	COG3188	usher protein
UGYR_11840	COG1073	alpha beta
UGYR_11850	COG0360	Binds together with S18 to 16S ribosomal RNA
UGYR_11855	COG2965	DNA replication, synthesis of RNA primer
UGYR_11865	COG0359	binds to the 23S rRNA
UGYR_11870	COG3061	Opacity-associated protein A
UGYR_11875	COG0545	Peptidyl-prolyl cis-trans isomerase
UGYR_11885	COG0737	Belongs to the 5'-nucleotidase family
UGYR_11890	COG1218	3'(2'),5'-bisphosphate nucleotidase
UGYR_11895	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
UGYR_11905	COG1253	flavin adenine dinucleotide binding
UGYR_11910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
UGYR_11915	COG0729	surface antigen
UGYR_11920	COG2911	Protein conserved in bacteria
UGYR_11925	COG2105	PFAM AIG2 family protein
UGYR_11930	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
UGYR_11940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
UGYR_11955	COG3423	Transcriptional regulator
UGYR_11970	COG0142	geranyltranstransferase activity
UGYR_11985	COG0697	spore germination
UGYR_11990	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
UGYR_11995	COG0642	Histidine kinase
UGYR_12000	COG0745	RESPONSE REGULATOR receiver
UGYR_12005	COG2027	D-alanyl-D-alanine carboxypeptidase
UGYR_12010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
UGYR_12015	COG1534	Rna-binding protein
UGYR_12020	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
UGYR_12025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
UGYR_12030	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
UGYR_12035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
UGYR_12040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
UGYR_12060	COG0195	Participates in both transcription termination and antitermination
UGYR_12070	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
UGYR_12085	COG1185	polyribonucleotide nucleotidyltransferase activity
UGYR_12095	COG0513	Belongs to the DEAD box helicase family
UGYR_12100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
UGYR_12105	COG0814	amino acid
UGYR_12130	COG3153	acetyltransferase
UGYR_12135	COG2827	Endonuclease containing a URI domain
UGYR_12140	COG0531	amino acid
UGYR_12145	COG1982	Orn Lys Arg decarboxylase major
UGYR_12155	COG3787	Belongs to the UPF0306 family
UGYR_12160	COG0702	epimerase
UGYR_12165	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
UGYR_12170	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
UGYR_12175	COG3454	Phosphonate metabolism
UGYR_12180	COG4778	phosphonate C-P lyase system protein PhnL
UGYR_12185	COG4107	phosphonate C-P lyase system protein PhnK
UGYR_12190	COG3627	carbon phosphorus lyase activity
UGYR_12195	COG3626	phosphonate metabolism
UGYR_12200	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
UGYR_12205	COG3624	Phosphonate C-P lyase system protein PhnG
UGYR_12220	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
UGYR_12225	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
UGYR_12240	COG2927	DNA polymerase III (CHI subunit)
UGYR_12245	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
UGYR_12250	COG0795	lipopolysaccharide-transporting ATPase activity
UGYR_12255	COG0795	lipopolysaccharide-transporting ATPase activity
UGYR_12265	COG0582	viral genome integration into host DNA
UGYR_12270	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
UGYR_12290	COG1196	nuclear chromosome segregation
UGYR_12300	COG1401	restriction endodeoxyribonuclease activity
UGYR_12380	COG2963	transposase activity
UGYR_12385	COG2801	Transposase and inactivated derivatives
UGYR_12455	COG3077	Addiction module antitoxin, RelB DinJ family
UGYR_12515	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
UGYR_12540	COG3119	arylsulfatase activity
UGYR_12550	COG1349	DNA-binding transcription factor activity
UGYR_12560	COG2222	sugar isomerase
UGYR_12565	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_12570	COG3715	PTS system
UGYR_12575	COG3716	PTS system mannose fructose sorbose family IID component
UGYR_12585	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
UGYR_12595	COG1028	Short-chain dehydrogenase reductase Sdr
UGYR_12605	COG0641	radical SAM
UGYR_12610	COG3119	arylsulfatase activity
UGYR_12620	COG0191	fructose-bisphosphate aldolase activity
UGYR_12635	COG0859	PFAM glycosyl transferase family 9
UGYR_12650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UGYR_12655	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UGYR_12665	COG2376	Dihydroxyacetone kinase
UGYR_12670	COG1461	Dihydroxyacetone kinase
UGYR_12675	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
UGYR_12675	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
UGYR_12675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
UGYR_12685	COG3706	GGDEF domain
UGYR_12715	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
UGYR_12730	COG2823	Periplasmic or secreted lipoprotein
UGYR_12735	COG4667	esterase of the alpha-beta hydrolase superfamily
UGYR_12740	COG0084	hydrolase, TatD family'
UGYR_12745	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
UGYR_12750	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
UGYR_12760	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
UGYR_12770	COG3726	membrane protein affecting hemolysin expression
UGYR_12775	COG0560	Phosphoserine phosphatase
UGYR_12790	COG0488	(ABC) transporter
UGYR_12810	COG0741	lytic transglycosylase activity
UGYR_12815	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
UGYR_12820	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
UGYR_12825	COG0406	alpha-ribazole phosphatase activity
UGYR_12830	COG2207	Transcriptional regulator
UGYR_12830	COG3708	Transcriptional regulator
UGYR_12835	COG3045	CreA protein
UGYR_12840	COG0745	RESPONSE REGULATOR receiver
UGYR_12865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
UGYR_12870	COG0521	Mo-molybdopterin cofactor biosynthetic process
UGYR_12875	COG0477	Major facilitator Superfamily
UGYR_12885	COG1584	GPR1 FUN34 yaaH family protein
UGYR_12890	COG0443	Heat shock 70 kDa protein
UGYR_12900	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
UGYR_12905	COG0583	DNA-binding transcription factor activity
UGYR_12915	COG0196	riboflavin kinase activity
UGYR_12925	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
UGYR_12930	COG1047	Peptidyl-prolyl cis-trans
UGYR_12935	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
UGYR_12945	COG0505	Belongs to the CarA family
UGYR_12950	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
UGYR_12960	COG2966	Psort location CytoplasmicMembrane, score
UGYR_12985	COG2967	ApaG domain
UGYR_12990	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
UGYR_12995	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
UGYR_13000	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UGYR_13005	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
UGYR_13015	COG0564	pseudouridine synthase activity
UGYR_13020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
UGYR_13025	COG0417	DNA replication proofreading
UGYR_13030	COG0586	Pfam SNARE associated Golgi protein
UGYR_13040	COG1178	ABC-type Fe3 transport system permease component
UGYR_13045	COG4143	(ABC) transporter
UGYR_13055	COG2814	Major facilitator Superfamily
UGYR_13065	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
UGYR_13070	COG0473	3-isopropylmalate dehydrogenase activity
UGYR_13085	COG1022	Amp-dependent synthetase and ligase
UGYR_13090	COG0028	Belongs to the TPP enzyme family
UGYR_13100	COG1609	Transcriptional regulator
UGYR_13105	COG1943	Transposase
UGYR_13110	COG0675	Transposase, IS605 OrfB family
UGYR_13125	COG0275	rRNA processing
UGYR_13130	COG3116	cell division
UGYR_13135	COG0768	penicillin binding
UGYR_13140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
UGYR_13145	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
UGYR_13160	COG0772	Belongs to the SEDS family
UGYR_13165	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
UGYR_13170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
UGYR_13180	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
UGYR_13185	COG0849	cell division
UGYR_13190	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
UGYR_13215	COG0494	nUDIX hydrolase
UGYR_13230	COG0237	dephospho-CoA kinase activity
UGYR_13235	COG0516	GMP reductase activity
UGYR_13240	COG1459	type II secretion system
UGYR_13245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
UGYR_13250	COG4969	Belongs to the N-Me-Phe pilin family
UGYR_13265	COG3725	Membrane protein required for beta-lactamase induction
UGYR_13270	COG1113	amino acid transport
UGYR_13275	COG2186	Transcriptional regulator
UGYR_13280	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
UGYR_13285	COG0508	dehydrogenase complex catalyzes the overall conversion of
UGYR_13290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
UGYR_13300	COG1049	propionate catabolic process, 2-methylcitrate cycle
UGYR_13305	COG3112	Uncharacterised protein family (UPF0231)
UGYR_13320	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
UGYR_13330	COG2132	Multicopper oxidase
UGYR_13340	COG0288	reversible hydration of carbon dioxide
UGYR_13345	COG1131	(ABC) transporter
UGYR_13350	COG0842	Transport permease protein
UGYR_13355	COG0726	polysaccharide deacetylase
UGYR_13360	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
UGYR_13365	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
UGYR_13370	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
UGYR_13375	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
UGYR_13380	COG0617	tRNA 3'-terminal CCA addition
UGYR_13390	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
UGYR_13395	COG1489	DNA binding
UGYR_13400	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
UGYR_13405	COG1643	Atp-dependent helicase
UGYR_13410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
UGYR_13415	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
UGYR_13425	COG0316	Belongs to the HesB IscA family
UGYR_13430	COG2860	membrane
UGYR_13440	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
UGYR_13445	COG0232	Belongs to the dGTPase family. Type 2 subfamily
UGYR_13450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
UGYR_13460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
UGYR_13465	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
UGYR_13470	COG3956	TIGRFAM MazG family protein
UGYR_13475	COG0504	CTP synthase activity
UGYR_13485	COG0602	queuosine metabolic process
UGYR_13490	COG0720	synthase
UGYR_13495	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
UGYR_13520	COG2234	aminopeptidase activity
UGYR_13525	COG1648	precorrin-2 dehydrogenase activity
UGYR_13525	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
UGYR_13530	COG0175	sulfate reduction
UGYR_13535	COG2895	sulfate adenylyltransferase (ATP) activity
UGYR_13540	COG0529	Catalyzes the synthesis of activated sulfate
UGYR_13550	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
UGYR_13560	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
UGYR_13565	COG0585	pseudouridine synthase activity
UGYR_13570	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
UGYR_13580	COG4942	peptidase
UGYR_13580	COG1388	LysM domain
UGYR_13585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
UGYR_13590	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
UGYR_13650	COG0784	Response regulator, receiver
UGYR_13650	COG2205	protein histidine kinase activity
UGYR_13670	COG0741	lytic transglycosylase activity
UGYR_13725	COG4789	Type iii secretion
UGYR_13735	COG1157	protein secretion by the type III secretion system
UGYR_13800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
UGYR_13820	COG3397	chitin binding
UGYR_13830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
UGYR_13885	COG3031	protein transport across the cell outer membrane
UGYR_13910	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
UGYR_13910	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
UGYR_13925	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
UGYR_13930	COG2137	regulation of response to DNA damage stimulus
UGYR_13935	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
UGYR_13940	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
UGYR_13965	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
UGYR_13970	COG1238	metal cluster binding
UGYR_13975	COG2918	glutathione biosynthetic process
UGYR_13980	COG1854	S-ribosylhomocysteine lyase activity
UGYR_13985	COG4536	flavin adenine dinucleotide binding
UGYR_13990	COG4137	Cytochrome C assembly protein
UGYR_13995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
UGYR_14000	COG0228	four-way junction DNA binding
UGYR_14005	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
UGYR_14010	COG0336	Belongs to the RNA methyltransferase TrmD family
UGYR_14015	COG0335	large ribosomal subunit rRNA binding
UGYR_14020	COG3137	Salt-induced outer membrane protein
UGYR_14025	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
UGYR_14030	COG3279	Response regulator of the LytR AlgR family
UGYR_14035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UGYR_14040	COG1605	Chorismate mutase
UGYR_14040	COG0287	Prephenate dehydrogenase
UGYR_14045	COG1605	Chorismate mutase
UGYR_14045	COG0077	Prephenate dehydratase
UGYR_14050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
UGYR_14055	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
UGYR_14060	COG0564	pseudouridine synthase activity
UGYR_14105	COG3021	interspecies interaction between organisms
UGYR_14110	COG0741	lytic transglycosylase activity
UGYR_14110	COG1388	LysM domain
UGYR_14120	COG2226	methyltransferase
UGYR_14130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
UGYR_14140	COG1960	acyl-CoA dehydrogenase activity
UGYR_14145	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
UGYR_14150	COG0121	glutamine amidotransferase
UGYR_14155	COG3034	peptidoglycan biosynthetic process
UGYR_14160	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UGYR_14165	COG1805	sodium ion transport
UGYR_14170	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UGYR_14175	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UGYR_14180	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
UGYR_14190	COG1477	protein flavinylation
UGYR_14195	COG2991	Protein conserved in bacteria
UGYR_14205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
UGYR_14210	COG2195	Cleaves the N-terminal amino acid of tripeptides
UGYR_14215	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
UGYR_14270	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
UGYR_14290	COG4126	flavin adenine dinucleotide binding
UGYR_14300	COG2974	May be involved in recombination
UGYR_14305	COG1940	carbohydrate kinase activity
UGYR_14310	COG0419	ATPase involved in DNA repair
UGYR_14320	COG0745	RESPONSE REGULATOR receiver
UGYR_14325	COG5002	protein histidine kinase activity
UGYR_14335	COG1114	Component of the transport system for branched-chain amino acids
UGYR_14340	COG1113	amino acid transport
UGYR_14345	COG0366	Alpha amylase catalytic
UGYR_14350	COG0300	oxidoreductase activity
UGYR_14355	COG0450	alkyl hydroperoxide reductase
UGYR_14360	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
UGYR_14365	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
UGYR_14375	COG1862	Preprotein translocase
UGYR_14380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UGYR_14385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
UGYR_14390	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
UGYR_14395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UGYR_14395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
UGYR_14400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
UGYR_14410	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
UGYR_14415	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
UGYR_14420	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
UGYR_14425	COG0142	geranyltranstransferase activity
UGYR_14450	COG1840	ABC-type Fe3 transport system, periplasmic component
UGYR_14460	COG0693	protein deglycase activity
UGYR_14465	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
UGYR_14470	COG1666	GTP binding
UGYR_14475	COG2814	Major facilitator Superfamily
UGYR_14485	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
UGYR_14490	COG1845	cytochrome c oxidase, subunit III
UGYR_14495	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
UGYR_14500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
UGYR_14510	COG2223	nitrite transmembrane transporter activity
UGYR_14515	COG3056	Lipoprotein
UGYR_14520	COG0271	Belongs to the BolA IbaG family
UGYR_14530	COG0740	serine-type endopeptidase activity
UGYR_14535	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
UGYR_14540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
UGYR_14545	COG0776	regulation of translation
UGYR_14550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
UGYR_14555	COG1555	photosystem II stabilization
UGYR_14560	COG0824	Thioesterase
UGYR_14565	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
UGYR_14570	COG4533	DNA binding
UGYR_14585	COG1522	sequence-specific DNA binding
UGYR_14590	COG1132	(ABC) transporter
UGYR_14595	COG1132	(ABC) transporter
UGYR_14600	COG0347	Belongs to the P(II) protein family
UGYR_14605	COG0004	ammonium transporteR
UGYR_14610	COG1946	Acyl-CoA thioesterase
UGYR_14615	COG3695	enzyme binding
UGYR_14635	COG0254	rRNA binding
UGYR_14640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
UGYR_14645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UGYR_14650	COG1309	transcriptional regulator
UGYR_14655	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
UGYR_14660	COG3264	Mechanosensitive ion channel
UGYR_14660	COG1196	nuclear chromosome segregation
UGYR_14670	COG2832	Protein of unknown function (DUF454)
UGYR_14675	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
UGYR_14700	COG0642	Histidine kinase
UGYR_14715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
UGYR_14720	COG0326	Molecular chaperone. Has ATPase activity
UGYR_14735	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
UGYR_14740	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
UGYR_14745	COG4651	solute:proton antiporter activity
UGYR_14745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
UGYR_14750	COG0737	Belongs to the 5'-nucleotidase family
UGYR_14765	COG0500	methyltransferase
UGYR_14790	COG1086	Polysaccharide biosynthesis protein
UGYR_14805	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
UGYR_14810	COG3735	TraB family
UGYR_14815	COG2217	Heavy metal translocating P-type atpase
UGYR_14820	COG0789	Transcriptional regulator
UGYR_14825	COG1585	Membrane protein implicated in regulation of membrane protease activity
UGYR_14830	COG0330	HflC and HflK could
UGYR_14835	COG3118	belongs to the thioredoxin family
UGYR_14840	COG0300	oxidoreductase activity
UGYR_14845	COG2755	lipolytic protein G-D-S-L family
UGYR_14850	COG4181	ATPase activity
UGYR_14855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
UGYR_14860	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
UGYR_14865	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
UGYR_14875	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
UGYR_14900	COG3188	usher protein
UGYR_14905	COG3121	Chaperone
UGYR_14935	COG2501	S4 domain
UGYR_14940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
UGYR_14955	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
UGYR_14960	COG1393	Belongs to the ArsC family
UGYR_14970	COG1022	Amp-dependent synthetase and ligase
UGYR_14995	COG3038	cytochrome b561
UGYR_15015	COG0745	RESPONSE REGULATOR receiver
UGYR_15025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
UGYR_15035	COG1215	transferase activity, transferring glycosyl groups
UGYR_15065	COG3706	GGDEF domain
UGYR_15065	COG0745	RESPONSE REGULATOR receiver
UGYR_15070	COG1309	transcriptional regulator
UGYR_15095	COG2197	response regulator
UGYR_15100	COG1278	Cold shock
UGYR_15105	COG1278	Cold shock
UGYR_15120	COG3706	GGDEF domain
UGYR_15130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
UGYR_15145	COG1686	Belongs to the peptidase S11 family
UGYR_15150	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
UGYR_15155	COG0772	Belongs to the SEDS family
UGYR_15160	COG0768	penicillin binding
UGYR_15165	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
UGYR_15170	COG0799	negative regulation of ribosome biogenesis
UGYR_15175	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
UGYR_15180	COG1466	dna polymerase III delta subunit
UGYR_15185	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
UGYR_15195	COG2888	peptidyl-tyrosine sulfation
UGYR_15200	COG1126	abc transporter atp-binding protein
UGYR_15205	COG0765	amino acid transport
UGYR_15210	COG0765	amino acid transport
UGYR_15225	COG0815	Transfers the fatty acyl group on membrane lipoproteins
UGYR_15230	COG4535	Mg2 and Co2 transporter CorC
UGYR_15235	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
UGYR_15240	COG1702	phosphate starvation-inducible protein PhoH
UGYR_15245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
UGYR_15250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
UGYR_15285	COG0367	asparagine synthase
UGYR_15290	COG0647	UMP catabolic process
UGYR_15295	COG1846	Transcriptional regulator
UGYR_15295	COG1940	carbohydrate kinase activity
UGYR_15300	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
UGYR_15305	COG0363	glucosamine-6-phosphate deaminase activity
UGYR_15310	COG1263	PTS System
UGYR_15310	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
UGYR_15310	COG2190	(PTS) system
UGYR_15335	COG0735	belongs to the Fur family
UGYR_15345	COG0840	transmembrane signaling receptor activity
UGYR_15355	COG0596	Alpha beta hydrolase
UGYR_15360	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
UGYR_15365	COG0033	Phosphoglucomutase
UGYR_15375	COG0745	RESPONSE REGULATOR receiver
UGYR_15380	COG2205	protein histidine kinase activity
UGYR_15385	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
UGYR_15390	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
UGYR_15410	COG3272	Protein of unknown function (DUF1722)
UGYR_15415	COG0415	Belongs to the DNA photolyase family
UGYR_15420	COG5212	phosphodiesterase
UGYR_15425	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
UGYR_15430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
UGYR_15435	COG1984	allophanate hydrolase subunit 2
UGYR_15440	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
UGYR_15470	COG2009	succinate dehydrogenase
UGYR_15475	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
UGYR_15480	COG1053	succinate dehydrogenase
UGYR_15485	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
UGYR_15490	COG0567	Dehydrogenase, E1 component
UGYR_15495	COG0508	dehydrogenase complex catalyzes the overall conversion of
UGYR_15500	COG0045	succinate-CoA ligase (ADP-forming) activity
UGYR_15505	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
UGYR_15510	COG0737	Belongs to the 5'-nucleotidase family
UGYR_15515	COG1271	oxidase subunit
UGYR_15520	COG1294	oxidase, subunit
UGYR_15525	COG4890	Cyd operon protein YbgT
UGYR_15530	COG3790	cyd operon protein YbgE
UGYR_15535	COG0824	Thioesterase
UGYR_15540	COG0811	peptide transport
UGYR_15545	COG0848	biopolymer transport protein
UGYR_15550	COG3064	Membrane
UGYR_15550	COG3064	Membrane
UGYR_15555	COG0823	Involved in the tonB-independent uptake of proteins
UGYR_15560	COG2885	chlorophyll binding
UGYR_15565	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
UGYR_15590	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
UGYR_15600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_15600	COG2205	protein histidine kinase activity
UGYR_15610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
UGYR_15615	COG0588	phosphoglycerate mutase activity
UGYR_15625	COG2017	converts alpha-aldose to the beta-anomer
UGYR_15635	COG1085	galactose-1-phosphate uridylyltransferase
UGYR_15640	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
UGYR_15650	COG2005	Transcriptional regulator
UGYR_15650	COG3585	molybdate ion transport
UGYR_15660	COG0725	ABC transporter, periplasmic molybdate-binding protein
UGYR_15665	COG4149	molybdate abc transporter
UGYR_15675	COG0561	phosphatase activity
UGYR_15680	COG2706	6-phosphogluconolactonase activity
UGYR_15695	COG0156	8-amino-7-oxononanoate synthase activity
UGYR_15700	COG2226	methyltransferase
UGYR_15705	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
UGYR_15715	COG0556	nucleotide-excision repair
UGYR_15720	COG4628	conserved protein (DUF2132)
UGYR_15745	COG0391	Required for morphogenesis under gluconeogenic growth conditions
UGYR_15750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
UGYR_15760	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
UGYR_15765	COG0314	molybdopterin synthase activity
UGYR_15770	COG0670	Belongs to the BI1 family
UGYR_15775	COG0842	Transport permease protein
UGYR_15780	COG0842	Transport permease protein
UGYR_15785	COG1131	(ABC) transporter
UGYR_15790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UGYR_15795	COG1309	transcriptional regulator
UGYR_15800	COG0513	Belongs to the DEAD box helicase family
UGYR_15805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
UGYR_15815	COG1686	Belongs to the peptidase S11 family
UGYR_15820	COG0277	FAD linked oxidase domain protein
UGYR_15830	COG1403	HNH endonuclease
UGYR_15840	COG2261	transglycosylase associated protein
UGYR_15850	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
UGYR_15860	COG3639	organic phosphonate transmembrane transporter activity
UGYR_15865	COG4807	Protein conserved in bacteria
UGYR_15870	COG2897	thiosulfate sulfurtransferase activity
UGYR_15875	COG1732	Glycine betaine
UGYR_15880	COG1174	glycine betaine transport
UGYR_15885	COG1125	glycine betaine transport
UGYR_15890	COG1174	glycine betaine transport
UGYR_15895	COG0531	amino acid
UGYR_15900	COG1982	Orn Lys Arg decarboxylase major
UGYR_15910	COG0697	spore germination
UGYR_15925	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
UGYR_15930	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
UGYR_15935	COG1126	abc transporter atp-binding protein
UGYR_15940	COG0765	amino acid transport
UGYR_15945	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_15960	COG5006	permease, DMT superfamily
UGYR_15965	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
UGYR_15970	COG2239	Acts as a magnesium transporter
UGYR_15985	COG0488	(ABC) transporter
UGYR_15990	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
UGYR_15995	COG0303	'Molybdopterin
UGYR_16015	COG0583	DNA-binding transcription factor activity
UGYR_16020	COG0477	Major facilitator Superfamily
UGYR_16025	COG0302	gtp cyclohydrolase
UGYR_16030	COG2311	Membrane
UGYR_16055	COG2949	membrane
UGYR_16060	COG0281	malic enzyme
UGYR_16070	COG0583	DNA-binding transcription factor activity
UGYR_16080	COG1346	cytolysis
UGYR_16085	COG1380	Effector of murein hydrolase LrgA
UGYR_16095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UGYR_16095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
UGYR_16100	COG0489	protein tyrosine kinase activity
UGYR_16105	COG0572	uridine kinase
UGYR_16110	COG0717	Belongs to the dCTP deaminase family
UGYR_16115	COG2982	Protein involved in outer membrane biogenesis
UGYR_16120	COG3069	C4-dicarboxylate transmembrane transporter activity
UGYR_16125	COG1253	flavin adenine dinucleotide binding
UGYR_16130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
UGYR_16135	COG1210	Utp--glucose-1-phosphate uridylyltransferase
UGYR_16140	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
UGYR_16145	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
UGYR_16145	COG0140	phosphoribosyl-ATP diphosphatase activity
UGYR_16155	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
UGYR_16160	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
UGYR_16165	COG0131	Imidazoleglycerol-phosphate dehydratase
UGYR_16165	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
UGYR_16170	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
UGYR_16175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
UGYR_16185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UGYR_16190	COG0625	glutathione transferase activity
UGYR_16205	COG0626	cystathionine gamma-synthase activity
UGYR_16215	COG1686	Belongs to the peptidase S11 family
UGYR_16220	COG1760	l-serine dehydratase
UGYR_16225	COG0814	amino acid
UGYR_16230	COG1349	DNA-binding transcription factor activity
UGYR_16240	COG0671	phosphoesterase, PA-phosphatase related
UGYR_16250	COG0569	domain protein
UGYR_16250	COG2985	domain, Protein
UGYR_16255	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
UGYR_16270	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
UGYR_16275	COG3842	ATPase activity
UGYR_16280	COG1176	ABC-type spermidine putrescine transport system, permease component I
UGYR_16285	COG1177	transmembrane transport
UGYR_16300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_16305	COG4160	amino acid transport
UGYR_16310	COG4215	(ABC) transporter
UGYR_16315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
UGYR_16320	COG1126	abc transporter atp-binding protein
UGYR_16330	COG0393	Putative heavy-metal-binding
UGYR_16335	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
UGYR_16340	COG0702	epimerase
UGYR_16345	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
UGYR_16350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
UGYR_16355	COG1151	hydroxylamine reductase activity
UGYR_16360	COG2431	L-lysine efflux transmembrane transporter activity
UGYR_16365	COG3593	DNA synthesis involved in DNA repair
UGYR_16375	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
UGYR_16385	COG1278	Cold shock
UGYR_16390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
UGYR_16395	COG0542	response to heat
UGYR_16400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
UGYR_16410	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
UGYR_16420	COG0492	ferredoxin-NADP+ reductase activity
UGYR_16425	COG1522	sequence-specific DNA binding
UGYR_16430	COG3107	peptidoglycan biosynthetic process
UGYR_16430	COG1674	ftsk spoiiie
UGYR_16435	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
UGYR_16440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
UGYR_16445	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
UGYR_16450	COG2814	Major facilitator Superfamily
UGYR_16455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
UGYR_16460	COG1882	Formate acetyltransferase
UGYR_16465	COG2116	formate transmembrane transporter activity
UGYR_16470	COG1944	ATP diphosphatase activity
UGYR_16475	COG0252	asparaginase activity
UGYR_16485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
UGYR_16495	COG0539	negative regulation of cytoplasmic translation
UGYR_16505	COG2333	competence protein COMEC
UGYR_16505	COG0658	competence protein
UGYR_16515	COG1663	tetraacyldisaccharide 4'-kinase activity
UGYR_16520	COG5383	Protein conserved in bacteria
UGYR_16525	COG1278	Cold shock
UGYR_16530	COG1278	Cold shock
UGYR_16535	COG2835	tetraacyldisaccharide 4'-kinase activity
UGYR_16540	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
UGYR_16545	COG3173	Aminoglycoside phosphotransferase
UGYR_16550	COG1434	Gram-negative-bacterium-type cell wall biogenesis
UGYR_16555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
UGYR_16560	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
UGYR_16565	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
UGYR_16570	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
UGYR_16575	COG2989	Protein conserved in bacteria
UGYR_16580	COG3108	Peptidase M15
UGYR_16585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
UGYR_16590	COG1448	Aminotransferase