locus-tag	class	description
ND011_00010	COG0592	DNA-directed DNA polymerase activity
ND011_00020	COG0187	DNA topoisomerase II activity
ND011_00025	COG0561	phosphatase activity
ND011_00030	COG0823	Involved in the tonB-independent uptake of proteins
ND011_00035	COG5645	(Lipo)protein
ND011_00050	COG0569	domain protein
ND011_00050	COG2985	domain, Protein
ND011_00055	COG3977	Valine--pyruvate aminotransferase
ND011_00060	COG2885	chlorophyll binding
ND011_00080	COG2818	Glycosylase
ND011_00130	COG2213	PTS system mannitol-specific
ND011_00130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND011_00140	COG3722	fumarate hydratase activity
ND011_00150	COG2258	MOSC domain
ND011_00155	COG0840	transmembrane signaling receptor activity
ND011_00160	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ND011_00175	COG0437	4 iron, 4 sulfur cluster binding
ND011_00180	COG2864	formate dehydrogenase
ND011_00190	COG1921	L-seryl-tRNASec selenium transferase activity
ND011_00195	COG3276	selenocysteine insertion sequence binding
ND011_00200	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
ND011_00210	COG3274	enterobacterial common antigen metabolic process
ND011_00220	COG0582	viral genome integration into host DNA
ND011_00255	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
ND011_00260	COG2986	histidine ammonia-lyase
ND011_00280	COG2194	sulfuric ester hydrolase activity
ND011_00285	COG2197	response regulator
ND011_00290	COG3851	Histidine kinase
ND011_00295	COG2271	Major facilitator Superfamily
ND011_00305	COG0747	negative chemotaxis
ND011_00310	COG0601	transmembrane transport
ND011_00315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ND011_00320	COG0444	Belongs to the ABC transporter superfamily
ND011_00325	COG4608	Belongs to the ABC transporter superfamily
ND011_00330	COG2194	sulfuric ester hydrolase activity
ND011_00355	COG1215	transferase activity, transferring glycosyl groups
ND011_00360	COG1215	transferase activity, transferring glycosyl groups
ND011_00365	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ND011_00370	COG3118	belongs to the thioredoxin family
ND011_00370	COG0457	Tetratricopeptide repeat
ND011_00375	COG2199	diguanylate cyclase activity
ND011_00375	COG2200	EAL domain
ND011_00380	COG1301	dicarboxylic acid transport
ND011_00385	COG0612	Peptidase, M16
ND011_00390	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ND011_00395	COG1942	4-Oxalocrotonate Tautomerase
ND011_00400	COG2200	EAL domain
ND011_00405	COG2134	cdp-diacylglycerol pyrophosphatase
ND011_00410	COG1295	ribonuclease BN
ND011_00420	COG1301	dicarboxylic acid transport
ND011_00425	COG0626	cystathionine gamma-synthase activity
ND011_00435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ND011_00440	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ND011_00445	COG0339	signal peptide processing
ND011_00450	COG0742	ribosomal rna small subunit methyltransferase
ND011_00460	COG0589	response to stress
ND011_00470	COG0306	phosphate transporter
ND011_00475	COG2081	HI0933 family
ND011_00485	COG1247	-acetyltransferase
ND011_00495	COG1741	Belongs to the pirin family
ND011_00500	COG1609	Transcriptional regulator
ND011_00505	COG2610	gluconate transmembrane transporter activity
ND011_00510	COG3265	gluconokinase activity
ND011_00515	COG2095	MarC family integral membrane protein
ND011_00520	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ND011_00525	COG3275	phosphorelay sensor kinase activity
ND011_00530	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ND011_00535	COG1523	belongs to the glycosyl hydrolase 13 family
ND011_00540	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ND011_00545	COG0297	glycogen (starch) synthase activity
ND011_00550	COG0058	SHG alpha-glucan phosphorylase activity
ND011_00555	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ND011_00560	COG1349	DNA-binding transcription factor activity
ND011_00565	COG0705	Rhomboid family
ND011_00575	COG2909	trisaccharide binding
ND011_00580	COG0058	SHG alpha-glucan phosphorylase activity
ND011_00585	COG1640	4-alpha-glucanotransferase
ND011_00595	COG1040	competence protein
ND011_00600	COG0596	Alpha beta hydrolase
ND011_00620	COG1918	ferrous iron import across plasma membrane
ND011_00625	COG2183	response to ionizing radiation
ND011_00650	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ND011_00665	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ND011_00675	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ND011_00680	COG1011	Hydrolase
ND011_00690	COG0494	nUDIX hydrolase
ND011_00695	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ND011_00720	COG4796	Type ii and iii secretion system protein
ND011_00725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ND011_00745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ND011_00755	COG0180	Tryptophanyl-tRNA synthetase
ND011_00775	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ND011_00780	COG0402	S-adenosylhomocysteine deaminase activity
ND011_00785	COG0738	Major facilitator superfamily
ND011_00800	COG1609	Transcriptional regulator
ND011_00805	COG1486	melibiose metabolic process
ND011_00810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ND011_00825	COG1289	transmembrane transporter activity
ND011_00830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ND011_00835	COG1765	OsmC-like protein
ND011_00860	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ND011_00865	COG3954	Phosphoribulokinase
ND011_00875	COG0429	hydrolase of the alpha beta-hydrolase fold
ND011_00885	COG0859	PFAM glycosyl transferase family 9
ND011_00890	COG1216	Glycosyl transferase, family 2
ND011_00895	COG0488	(ABC) transporter
ND011_00900	COG2249	NAD(P)H dehydrogenase (quinone) activity
ND011_00910	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
ND011_00915	COG1047	Peptidyl-prolyl cis-trans
ND011_00925	COG0545	Peptidyl-prolyl cis-trans isomerase
ND011_00930	COG2964	Protein conserved in bacteria
ND011_00940	COG2923	Belongs to the DsrF TusC family
ND011_00945	COG2168	tRNA wobble position uridine thiolation
ND011_00950	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ND011_00955	COG0049	tRNA binding
ND011_00965	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ND011_00980	COG0051	transcription antitermination factor activity, RNA binding
ND011_00985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ND011_00995	COG0089	rRNA binding
ND011_01000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ND011_01005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ND011_01010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ND011_01020	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ND011_01025	COG0255	Belongs to the universal ribosomal protein uL29 family
ND011_01030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ND011_01035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ND011_01045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ND011_01070	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ND011_01075	COG1841	ribosomal large subunit assembly
ND011_01080	COG0200	Binds to the 23S rRNA
ND011_01085	COG0201	protein transport
ND011_01090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ND011_01095	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ND011_01105	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ND011_01115	COG0203	ribosomal protein L17
ND011_01120	COG0789	Transcriptional regulator
ND011_01125	COG3036	rescue of stalled ribosome
ND011_01130	COG1970	mechanosensitive ion channel activity
ND011_01140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ND011_01140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ND011_01145	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ND011_01150	COG0242	peptide deformylase activity
ND011_01155	COG0758	DNA mediated transformation
ND011_01160	COG2922	Belongs to the Smg family
ND011_01165	COG0551	DNA topoisomerase type I activity
ND011_01170	COG0009	L-threonylcarbamoyladenylate synthase
ND011_01180	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
ND011_01210	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ND011_01215	COG3162	membrane
ND011_01220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ND011_01225	COG1301	dicarboxylic acid transport
ND011_01235	COG2391	methyltransferase activity
ND011_01240	COG0425	Belongs to the sulfur carrier protein TusA family
ND011_01245	COG1086	Polysaccharide biosynthesis protein
ND011_01250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ND011_01255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ND011_01260	COG2089	acid synthase
ND011_01280	COG1083	cytidylyl-transferase
ND011_01280	COG2755	lipolytic protein G-D-S-L family
ND011_01285	COG1028	Short-chain dehydrogenase reductase Sdr
ND011_01305	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ND011_01305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ND011_01310	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ND011_01330	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ND011_01350	COG1309	transcriptional regulator
ND011_01355	COG4232	protein-disulfide reductase activity
ND011_01365	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ND011_01395	COG1509	lysine 2,3-aminomutase activity
ND011_01405	COG3397	chitin binding
ND011_01425	COG3188	usher protein
ND011_01445	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ND011_01450	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
ND011_01455	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ND011_01460	COG1053	succinate dehydrogenase
ND011_01465	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
ND011_01470	COG3264	Mechanosensitive ion channel
ND011_01470	COG1511	domain protein
ND011_01475	COG0688	phosphatidylethanolamine metabolic process
ND011_01480	COG1162	GTPase activity
ND011_01485	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
ND011_01505	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ND011_01510	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ND011_01510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ND011_01515	COG0802	atpase or kinase
ND011_01520	COG0860	N-Acetylmuramoyl-L-alanine amidase
ND011_01530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ND011_01540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ND011_01545	COG0330	HflC and HflK could
ND011_01550	COG0330	HflC and HflK could
ND011_01555	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
ND011_01560	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ND011_01565	COG1959	2 iron, 2 sulfur cluster binding
ND011_01570	COG0557	exoribonuclease II activity
ND011_01575	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ND011_01595	COG3121	Chaperone
ND011_01600	COG3188	usher protein
ND011_01620	COG1073	alpha beta
ND011_01630	COG0360	Binds together with S18 to 16S ribosomal RNA
ND011_01635	COG2965	DNA replication, synthesis of RNA primer
ND011_01640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ND011_01645	COG0359	binds to the 23S rRNA
ND011_01650	COG3061	Opacity-associated protein A
ND011_01655	COG0545	Peptidyl-prolyl cis-trans isomerase
ND011_01665	COG0737	Belongs to the 5'-nucleotidase family
ND011_01670	COG1218	3'(2'),5'-bisphosphate nucleotidase
ND011_01675	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
ND011_01685	COG1253	flavin adenine dinucleotide binding
ND011_01690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ND011_01695	COG0729	surface antigen
ND011_01700	COG2911	Protein conserved in bacteria
ND011_01705	COG2105	PFAM AIG2 family protein
ND011_01710	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ND011_01720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ND011_01735	COG3423	Transcriptional regulator
ND011_01750	COG0142	geranyltranstransferase activity
ND011_01765	COG0697	spore germination
ND011_01770	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ND011_01775	COG0642	Histidine kinase
ND011_01780	COG0745	RESPONSE REGULATOR receiver
ND011_01785	COG2027	D-alanyl-D-alanine carboxypeptidase
ND011_01795	COG1534	Rna-binding protein
ND011_01800	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ND011_01810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ND011_01815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ND011_01820	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ND011_01840	COG0195	Participates in both transcription termination and antitermination
ND011_01850	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ND011_01865	COG1185	polyribonucleotide nucleotidyltransferase activity
ND011_01875	COG0513	Belongs to the DEAD box helicase family
ND011_01880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ND011_01895	COG0826	peptidase U32
ND011_01900	COG0826	peptidase U32
ND011_01905	COG3154	lipid carrier protein
ND011_01910	COG3153	acetyltransferase
ND011_01915	COG2827	Endonuclease containing a URI domain
ND011_01920	COG0531	amino acid
ND011_01925	COG1982	Orn Lys Arg decarboxylase major
ND011_01935	COG3787	Belongs to the UPF0306 family
ND011_01940	COG0702	epimerase
ND011_01945	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ND011_01950	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
ND011_01955	COG3454	Phosphonate metabolism
ND011_01960	COG4778	phosphonate C-P lyase system protein PhnL
ND011_01965	COG4107	phosphonate C-P lyase system protein PhnK
ND011_01970	COG3627	carbon phosphorus lyase activity
ND011_01975	COG3626	phosphonate metabolism
ND011_01980	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ND011_01985	COG3624	Phosphonate C-P lyase system protein PhnG
ND011_02005	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
ND011_02020	COG2927	DNA polymerase III (CHI subunit)
ND011_02025	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ND011_02030	COG0795	lipopolysaccharide-transporting ATPase activity
ND011_02035	COG0795	lipopolysaccharide-transporting ATPase activity
ND011_02075	COG3077	Addiction module antitoxin, RelB DinJ family
ND011_02180	COG5492	domain, Protein
ND011_02200	COG3119	arylsulfatase activity
ND011_02205	COG1349	DNA-binding transcription factor activity
ND011_02215	COG2222	sugar isomerase
ND011_02220	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND011_02225	COG3715	PTS system
ND011_02230	COG3716	PTS system mannose fructose sorbose family IID component
ND011_02240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ND011_02250	COG1028	Short-chain dehydrogenase reductase Sdr
ND011_02260	COG0641	radical SAM
ND011_02265	COG3119	arylsulfatase activity
ND011_02290	COG0859	PFAM glycosyl transferase family 9
ND011_02305	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND011_02310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ND011_02320	COG2376	Dihydroxyacetone kinase
ND011_02325	COG1461	Dihydroxyacetone kinase
ND011_02330	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
ND011_02330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND011_02330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ND011_02370	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
ND011_02385	COG2823	Periplasmic or secreted lipoprotein
ND011_02395	COG4667	esterase of the alpha-beta hydrolase superfamily
ND011_02400	COG0084	hydrolase, TatD family'
ND011_02405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ND011_02420	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ND011_02430	COG3726	membrane protein affecting hemolysin expression
ND011_02435	COG0560	Phosphoserine phosphatase
ND011_02450	COG0488	(ABC) transporter
ND011_02475	COG0741	lytic transglycosylase activity
ND011_02480	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
ND011_02485	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
ND011_02490	COG0406	alpha-ribazole phosphatase activity
ND011_02495	COG3708	Transcriptional regulator
ND011_02495	COG2207	Transcriptional regulator
ND011_02500	COG3045	CreA protein
ND011_02505	COG0745	RESPONSE REGULATOR receiver
ND011_02540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ND011_02545	COG0521	Mo-molybdopterin cofactor biosynthetic process
ND011_02550	COG0477	Major facilitator Superfamily
ND011_02560	COG1584	GPR1 FUN34 yaaH family protein
ND011_02565	COG0443	Heat shock 70 kDa protein
ND011_02575	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ND011_02580	COG0583	DNA-binding transcription factor activity
ND011_02590	COG0196	riboflavin kinase activity
ND011_02600	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ND011_02605	COG1047	Peptidyl-prolyl cis-trans
ND011_02610	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ND011_02625	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ND011_02635	COG2966	Psort location CytoplasmicMembrane, score
ND011_02660	COG2967	ApaG domain
ND011_02665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ND011_02670	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ND011_02680	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ND011_02690	COG0564	pseudouridine synthase activity
ND011_02695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ND011_02700	COG0417	DNA replication proofreading
ND011_02705	COG0586	Pfam SNARE associated Golgi protein
ND011_02715	COG1178	ABC-type Fe3 transport system permease component
ND011_02720	COG4143	(ABC) transporter
ND011_02735	COG2814	Major facilitator Superfamily
ND011_02745	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ND011_02750	COG0473	3-isopropylmalate dehydrogenase activity
ND011_02765	COG1022	Amp-dependent synthetase and ligase
ND011_02770	COG0028	Belongs to the TPP enzyme family
ND011_02795	COG0275	rRNA processing
ND011_02800	COG3116	cell division
ND011_02805	COG0768	penicillin binding
ND011_02810	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ND011_02815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ND011_02830	COG0772	Belongs to the SEDS family
ND011_02835	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ND011_02840	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ND011_02850	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ND011_02855	COG0849	cell division
ND011_02860	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ND011_02885	COG0494	nUDIX hydrolase
ND011_02905	COG0516	GMP reductase activity
ND011_02910	COG1459	type II secretion system
ND011_02915	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ND011_02920	COG4969	Belongs to the N-Me-Phe pilin family
ND011_02935	COG3725	Membrane protein required for beta-lactamase induction
ND011_02940	COG1113	amino acid transport
ND011_02945	COG2186	Transcriptional regulator
ND011_02950	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ND011_02955	COG0508	dehydrogenase complex catalyzes the overall conversion of
ND011_02960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ND011_02970	COG1049	propionate catabolic process, 2-methylcitrate cycle
ND011_02975	COG3112	Uncharacterised protein family (UPF0231)
ND011_02990	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ND011_03000	COG2132	Multicopper oxidase
ND011_03010	COG0288	reversible hydration of carbon dioxide
ND011_03015	COG1131	(ABC) transporter
ND011_03020	COG0842	Transport permease protein
ND011_03025	COG0726	polysaccharide deacetylase
ND011_03030	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ND011_03035	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ND011_03040	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ND011_03045	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ND011_03050	COG0617	tRNA 3'-terminal CCA addition
ND011_03065	COG1489	DNA binding
ND011_03070	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ND011_03075	COG1643	Atp-dependent helicase
ND011_03080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ND011_03085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ND011_03095	COG0316	Belongs to the HesB IscA family
ND011_03100	COG2860	membrane
ND011_03110	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ND011_03115	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ND011_03120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ND011_03130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ND011_03135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ND011_03140	COG3956	TIGRFAM MazG family protein
ND011_03145	COG0504	CTP synthase activity
ND011_03155	COG0602	queuosine metabolic process
ND011_03160	COG0720	synthase
ND011_03165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ND011_03175	COG0175	sulfate reduction
ND011_03190	COG2234	aminopeptidase activity
ND011_03195	COG1648	precorrin-2 dehydrogenase activity
ND011_03195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ND011_03200	COG0175	sulfate reduction
ND011_03205	COG2895	sulfate adenylyltransferase (ATP) activity
ND011_03210	COG0529	Catalyzes the synthesis of activated sulfate
ND011_03220	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ND011_03230	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ND011_03235	COG0585	pseudouridine synthase activity
ND011_03240	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ND011_03250	COG1388	LysM domain
ND011_03250	COG4942	peptidase
ND011_03255	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ND011_03260	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ND011_03330	COG0784	Response regulator, receiver
ND011_03330	COG2205	protein histidine kinase activity
ND011_03350	COG0741	lytic transglycosylase activity
ND011_03480	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ND011_03500	COG3397	chitin binding
ND011_03510	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ND011_03555	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ND011_03565	COG3031	protein transport across the cell outer membrane
ND011_03590	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ND011_03590	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ND011_03605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ND011_03610	COG2137	regulation of response to DNA damage stimulus
ND011_03615	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ND011_03620	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ND011_03660	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ND011_03665	COG1238	metal cluster binding
ND011_03670	COG2918	glutathione biosynthetic process
ND011_03675	COG1854	S-ribosylhomocysteine lyase activity
ND011_03680	COG4536	flavin adenine dinucleotide binding
ND011_03685	COG4137	Cytochrome C assembly protein
ND011_03690	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ND011_03700	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ND011_03705	COG0336	Belongs to the RNA methyltransferase TrmD family
ND011_03710	COG0335	large ribosomal subunit rRNA binding
ND011_03715	COG3137	Salt-induced outer membrane protein
ND011_03720	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
ND011_03725	COG3279	Response regulator of the LytR AlgR family
ND011_03730	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ND011_03735	COG1605	Chorismate mutase
ND011_03735	COG0287	Prephenate dehydrogenase
ND011_03740	COG1605	Chorismate mutase
ND011_03740	COG0077	Prephenate dehydratase
ND011_03750	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ND011_03755	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ND011_03760	COG0564	pseudouridine synthase activity
ND011_03765	COG1496	oxidoreductase activity
ND011_03770	COG0542	response to heat
ND011_03805	COG3021	interspecies interaction between organisms
ND011_03810	COG0741	lytic transglycosylase activity
ND011_03810	COG1388	LysM domain
ND011_03820	COG2226	methyltransferase
ND011_03830	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND011_03840	COG1960	acyl-CoA dehydrogenase activity
ND011_03845	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ND011_03850	COG0121	glutamine amidotransferase
ND011_03855	COG3034	peptidoglycan biosynthetic process
ND011_03865	COG1805	sodium ion transport
ND011_03870	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ND011_03875	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ND011_03880	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
ND011_03890	COG1477	protein flavinylation
ND011_03895	COG2991	Protein conserved in bacteria
ND011_03905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ND011_03910	COG2195	Cleaves the N-terminal amino acid of tripeptides
ND011_03915	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ND011_03920	COG1073	alpha beta
ND011_03935	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ND011_03970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ND011_03990	COG4126	flavin adenine dinucleotide binding
ND011_04000	COG2974	May be involved in recombination
ND011_04005	COG1940	carbohydrate kinase activity
ND011_04010	COG0419	ATPase involved in DNA repair
ND011_04015	COG0420	3'-5' exonuclease activity
ND011_04020	COG0745	RESPONSE REGULATOR receiver
ND011_04025	COG5002	protein histidine kinase activity
ND011_04040	COG1113	amino acid transport
ND011_04045	COG0366	Alpha amylase catalytic
ND011_04050	COG0300	oxidoreductase activity
ND011_04055	COG0450	alkyl hydroperoxide reductase
ND011_04060	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
ND011_04075	COG1862	Preprotein translocase
ND011_04080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ND011_04085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ND011_04090	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ND011_04095	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ND011_04095	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ND011_04100	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ND011_04110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ND011_04115	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ND011_04120	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ND011_04125	COG0142	geranyltranstransferase activity
ND011_04160	COG0693	protein deglycase activity
ND011_04165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ND011_04170	COG1666	GTP binding
ND011_04175	COG2814	Major facilitator Superfamily
ND011_04185	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ND011_04190	COG1845	cytochrome c oxidase, subunit III
ND011_04195	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ND011_04200	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ND011_04210	COG2223	nitrite transmembrane transporter activity
ND011_04215	COG3056	Lipoprotein
ND011_04220	COG0271	Belongs to the BolA IbaG family
ND011_04230	COG0740	serine-type endopeptidase activity
ND011_04235	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ND011_04240	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ND011_04245	COG0776	regulation of translation
ND011_04250	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ND011_04255	COG1555	photosystem II stabilization
ND011_04260	COG0824	Thioesterase
ND011_04265	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ND011_04270	COG4533	DNA binding
ND011_04285	COG1522	sequence-specific DNA binding
ND011_04290	COG1132	(ABC) transporter
ND011_04295	COG1132	(ABC) transporter
ND011_04300	COG0347	Belongs to the P(II) protein family
ND011_04305	COG0004	ammonium transporteR
ND011_04310	COG1946	Acyl-CoA thioesterase
ND011_04315	COG3695	enzyme binding
ND011_04340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ND011_04345	COG0254	rRNA binding
ND011_04350	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ND011_04355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND011_04360	COG1309	transcriptional regulator
ND011_04365	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
ND011_04370	COG1196	nuclear chromosome segregation
ND011_04370	COG3264	Mechanosensitive ion channel
ND011_04385	COG2832	Protein of unknown function (DUF454)
ND011_04390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ND011_04430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ND011_04435	COG0326	Molecular chaperone. Has ATPase activity
ND011_04450	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ND011_04455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ND011_04460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ND011_04460	COG4651	solute:proton antiporter activity
ND011_04465	COG0737	Belongs to the 5'-nucleotidase family
ND011_04470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ND011_04475	COG3735	TraB family
ND011_04480	COG2217	Heavy metal translocating P-type atpase
ND011_04485	COG0789	Transcriptional regulator
ND011_04490	COG1585	Membrane protein implicated in regulation of membrane protease activity
ND011_04495	COG0330	HflC and HflK could
ND011_04500	COG3118	belongs to the thioredoxin family
ND011_04505	COG0300	oxidoreductase activity
ND011_04510	COG2755	lipolytic protein G-D-S-L family
ND011_04515	COG4181	ATPase activity
ND011_04520	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
ND011_04525	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ND011_04530	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ND011_04535	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ND011_04540	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ND011_04565	COG3188	usher protein
ND011_04570	COG3121	Chaperone
ND011_04600	COG2501	S4 domain
ND011_04605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ND011_04620	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ND011_04625	COG1393	Belongs to the ArsC family
ND011_04635	COG1022	Amp-dependent synthetase and ligase
ND011_04660	COG3038	cytochrome b561
ND011_04690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ND011_04700	COG1215	transferase activity, transferring glycosyl groups
ND011_04720	COG3250	beta-galactosidase activity
ND011_04735	COG1309	transcriptional regulator
ND011_04765	COG2197	response regulator
ND011_04770	COG1278	Cold shock
ND011_04790	COG3706	GGDEF domain
ND011_04800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ND011_04810	COG2921	Belongs to the UPF0250 family
ND011_04815	COG1686	Belongs to the peptidase S11 family
ND011_04820	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ND011_04825	COG0772	Belongs to the SEDS family
ND011_04830	COG0768	penicillin binding
ND011_04835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ND011_04840	COG0799	negative regulation of ribosome biogenesis
ND011_04845	COG0582	viral genome integration into host DNA
ND011_04905	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ND011_04970	COG0305	Participates in initiation and elongation during chromosome replication
ND011_04995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ND011_05070	COG0616	signal peptide processing
ND011_05110	COG4386	tail sheath protein
ND011_05150	COG3299	homolog of phage Mu protein gp47
ND011_05165	COG5301	cellulose 1,4-beta-cellobiosidase activity
ND011_05175	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ND011_05180	COG1466	dna polymerase III delta subunit
ND011_05185	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
ND011_05195	COG2888	peptidyl-tyrosine sulfation
ND011_05200	COG1126	abc transporter atp-binding protein
ND011_05205	COG0765	amino acid transport
ND011_05210	COG0765	amino acid transport
ND011_05220	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ND011_05225	COG4535	Mg2 and Co2 transporter CorC
ND011_05230	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ND011_05235	COG1702	phosphate starvation-inducible protein PhoH
ND011_05240	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ND011_05245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ND011_05280	COG0367	asparagine synthase
ND011_05285	COG0647	UMP catabolic process
ND011_05290	COG1846	Transcriptional regulator
ND011_05290	COG1940	carbohydrate kinase activity
ND011_05295	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ND011_05305	COG1263	PTS System
ND011_05305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND011_05305	COG2190	(PTS) system
ND011_05330	COG0735	belongs to the Fur family
ND011_05340	COG0840	transmembrane signaling receptor activity
ND011_05350	COG0596	Alpha beta hydrolase
ND011_05355	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
ND011_05360	COG0033	Phosphoglucomutase
ND011_05370	COG0745	RESPONSE REGULATOR receiver
ND011_05375	COG2205	protein histidine kinase activity
ND011_05380	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ND011_05385	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ND011_05405	COG3272	Protein of unknown function (DUF1722)
ND011_05410	COG0415	Belongs to the DNA photolyase family
ND011_05415	COG5212	phosphodiesterase
ND011_05420	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ND011_05425	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ND011_05430	COG1984	allophanate hydrolase subunit 2
ND011_05435	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ND011_05470	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
ND011_05475	COG1053	succinate dehydrogenase
ND011_05480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ND011_05485	COG0567	Dehydrogenase, E1 component
ND011_05490	COG0508	dehydrogenase complex catalyzes the overall conversion of
ND011_05495	COG0045	succinate-CoA ligase (ADP-forming) activity
ND011_05500	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ND011_05505	COG0737	Belongs to the 5'-nucleotidase family
ND011_05510	COG1271	oxidase subunit
ND011_05515	COG1294	oxidase, subunit
ND011_05520	COG4890	Cyd operon protein YbgT
ND011_05525	COG3790	cyd operon protein YbgE
ND011_05530	COG0824	Thioesterase
ND011_05535	COG0811	peptide transport
ND011_05540	COG0848	biopolymer transport protein
ND011_05545	COG3064	Membrane
ND011_05545	COG3064	Membrane
ND011_05550	COG0823	Involved in the tonB-independent uptake of proteins
ND011_05555	COG2885	chlorophyll binding
ND011_05560	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
ND011_05600	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ND011_05610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND011_05610	COG2205	protein histidine kinase activity
ND011_05620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ND011_05625	COG0588	phosphoglycerate mutase activity
ND011_05635	COG2017	converts alpha-aldose to the beta-anomer
ND011_05645	COG1085	galactose-1-phosphate uridylyltransferase
ND011_05650	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ND011_05665	COG2005	Transcriptional regulator
ND011_05665	COG3585	molybdate ion transport
ND011_05675	COG0725	ABC transporter, periplasmic molybdate-binding protein
ND011_05680	COG4149	molybdate abc transporter
ND011_05690	COG0561	phosphatase activity
ND011_05695	COG2706	6-phosphogluconolactonase activity
ND011_05710	COG0156	8-amino-7-oxononanoate synthase activity
ND011_05715	COG2226	methyltransferase
ND011_05730	COG0556	nucleotide-excision repair
ND011_05735	COG4628	conserved protein (DUF2132)
ND011_05750	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ND011_05755	COG1120	ATPase activity
ND011_05760	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ND011_05765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ND011_05775	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
ND011_05780	COG0314	molybdopterin synthase activity
ND011_05785	COG0670	Belongs to the BI1 family
ND011_05790	COG0842	Transport permease protein
ND011_05795	COG0842	Transport permease protein
ND011_05800	COG1131	(ABC) transporter
ND011_05805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND011_05810	COG1309	transcriptional regulator
ND011_05815	COG0513	Belongs to the DEAD box helicase family
ND011_05820	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ND011_05830	COG1686	Belongs to the peptidase S11 family
ND011_05835	COG0277	FAD linked oxidase domain protein
ND011_05855	COG2261	transglycosylase associated protein
ND011_05865	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ND011_05875	COG3639	organic phosphonate transmembrane transporter activity
ND011_05880	COG4807	Protein conserved in bacteria
ND011_05885	COG2897	thiosulfate sulfurtransferase activity
ND011_05890	COG1732	Glycine betaine
ND011_05895	COG1174	glycine betaine transport
ND011_05900	COG1125	glycine betaine transport
ND011_05905	COG1174	glycine betaine transport
ND011_05910	COG0531	amino acid
ND011_05915	COG1982	Orn Lys Arg decarboxylase major
ND011_05925	COG0697	spore germination
ND011_05940	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ND011_05945	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
ND011_05950	COG1126	abc transporter atp-binding protein
ND011_05955	COG0765	amino acid transport
ND011_05960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND011_05980	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ND011_05985	COG2239	Acts as a magnesium transporter
ND011_05990	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ND011_05995	COG0488	(ABC) transporter
ND011_06000	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ND011_06005	COG0303	'Molybdopterin
ND011_06025	COG0583	DNA-binding transcription factor activity
ND011_06030	COG0477	Major facilitator Superfamily
ND011_06035	COG0302	gtp cyclohydrolase
ND011_06040	COG2311	Membrane
ND011_06065	COG2949	membrane
ND011_06070	COG0281	malic enzyme
ND011_06080	COG0583	DNA-binding transcription factor activity
ND011_06090	COG1346	cytolysis
ND011_06095	COG1380	Effector of murein hydrolase LrgA
ND011_06105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ND011_06105	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ND011_06110	COG0489	protein tyrosine kinase activity
ND011_06115	COG0572	uridine kinase
ND011_06120	COG0717	Belongs to the dCTP deaminase family
ND011_06125	COG2982	Protein involved in outer membrane biogenesis
ND011_06130	COG3069	C4-dicarboxylate transmembrane transporter activity
ND011_06135	COG1253	flavin adenine dinucleotide binding
ND011_06140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ND011_06145	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ND011_06150	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ND011_06160	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ND011_06160	COG0140	phosphoribosyl-ATP diphosphatase activity
ND011_06170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ND011_06180	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ND011_06180	COG0131	Imidazoleglycerol-phosphate dehydratase
ND011_06185	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ND011_06190	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ND011_06205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ND011_06210	COG0625	glutathione transferase activity
ND011_06225	COG0626	cystathionine gamma-synthase activity
ND011_06235	COG1686	Belongs to the peptidase S11 family
ND011_06240	COG1760	l-serine dehydratase
ND011_06245	COG0814	amino acid
ND011_06250	COG1349	DNA-binding transcription factor activity
ND011_06260	COG0671	phosphoesterase, PA-phosphatase related
ND011_06270	COG2985	domain, Protein
ND011_06270	COG0569	domain protein
ND011_06290	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
ND011_06295	COG3842	ATPase activity
ND011_06300	COG1176	ABC-type spermidine putrescine transport system, permease component I
ND011_06305	COG1177	transmembrane transport
ND011_06320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND011_06325	COG4160	amino acid transport
ND011_06330	COG4215	(ABC) transporter
ND011_06335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND011_06340	COG1126	abc transporter atp-binding protein
ND011_06350	COG0393	Putative heavy-metal-binding
ND011_06355	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ND011_06360	COG0702	epimerase
ND011_06365	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
ND011_06370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ND011_06375	COG1151	hydroxylamine reductase activity
ND011_06380	COG2431	L-lysine efflux transmembrane transporter activity
ND011_06385	COG3593	DNA synthesis involved in DNA repair
ND011_06390	COG2990	Protein conserved in bacteria
ND011_06395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND011_06405	COG1278	Cold shock
ND011_06410	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ND011_06415	COG0542	response to heat
ND011_06420	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ND011_06430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
ND011_06440	COG0492	ferredoxin-NADP+ reductase activity
ND011_06445	COG1522	sequence-specific DNA binding
ND011_06450	COG1674	ftsk spoiiie
ND011_06450	COG3107	peptidoglycan biosynthetic process
ND011_06455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ND011_06460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ND011_06465	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ND011_06470	COG2814	Major facilitator Superfamily
ND011_06475	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ND011_06480	COG1882	Formate acetyltransferase
ND011_06485	COG2116	formate transmembrane transporter activity
ND011_06490	COG1944	ATP diphosphatase activity
ND011_06495	COG0252	asparaginase activity
ND011_06505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ND011_06515	COG0539	negative regulation of cytoplasmic translation
ND011_06525	COG2333	competence protein COMEC
ND011_06525	COG0658	competence protein
ND011_06535	COG1663	tetraacyldisaccharide 4'-kinase activity
ND011_06540	COG5383	Protein conserved in bacteria
ND011_06550	COG1278	Cold shock
ND011_06555	COG2835	tetraacyldisaccharide 4'-kinase activity
ND011_06560	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ND011_06565	COG3173	Aminoglycoside phosphotransferase
ND011_06570	COG1434	Gram-negative-bacterium-type cell wall biogenesis
ND011_06575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ND011_06580	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
ND011_06590	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ND011_06595	COG2989	Protein conserved in bacteria
ND011_06600	COG3108	Peptidase M15
ND011_06605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ND011_06610	COG1448	Aminotransferase
ND011_06625	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ND011_06630	COG0308	aminopeptidase N
ND011_06635	COG0167	dihydroorotate dehydrogenase activity
ND011_06645	COG3217	Mosc domain protein beta barrel domain protein
ND011_06645	COG0633	Ferredoxin
ND011_06650	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ND011_06650	COG0116	Belongs to the methyltransferase superfamily
ND011_06655	COG0488	(ABC) transporter
ND011_06660	COG2995	paraquat-inducible protein a
ND011_06665	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ND011_06665	COG3008	intermembrane lipid transfer
ND011_06670	COG3009	Protein conserved in bacteria
ND011_06675	COG3130	regulation of translation
ND011_06680	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ND011_06685	COG1067	ATP-dependent peptidase activity
ND011_06690	COG3120	sequence-specific DNA binding
ND011_06700	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
ND011_06705	COG3070	regulator of competence-specific genes
ND011_06710	COG1289	transmembrane transporter activity
ND011_06715	COG3304	Inner membrane component domain
ND011_06720	COG0210	DNA helicase
ND011_06725	COG1803	Methylglyoxal synthase
ND011_06735	COG1832	CoA-binding protein
ND011_06740	COG3785	DNA binding
ND011_06745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ND011_06750	COG1254	Belongs to the acylphosphatase family
ND011_06755	COG2920	part of a sulfur-relay system
ND011_06765	COG0288	reversible hydration of carbon dioxide
ND011_06785	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ND011_06790	COG2943	transferase activity, transferring hexosyl groups
ND011_06805	COG0675	Transposase, IS605 OrfB family
ND011_06820	COG1560	Kdo2-lipid A biosynthetic process
ND011_06830	COG0628	permease
ND011_06855	COG0418	dihydroorotase activity
ND011_06860	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ND011_06870	COG1530	ribonuclease E activity
ND011_06875	COG0564	pseudouridine synthase activity
ND011_06880	COG0424	maF-like protein
ND011_06885	COG1399	metal-binding, possibly nucleic acid-binding protein
ND011_06890	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ND011_06900	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ND011_06905	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ND011_06915	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ND011_06920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ND011_06925	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ND011_06930	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ND011_06935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ND011_06940	COG0470	DNA polymerase III
ND011_06945	COG0084	hydrolase, TatD family'
ND011_06950	COG1263	PTS System
ND011_06950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND011_06955	COG0537	adenosine 5'-monophosphoramidase activity
ND011_06960	COG5633	Lipoprotein
ND011_06965	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
ND011_06980	COG3150	esterase
ND011_06985	COG1252	NADH dehydrogenase
ND011_06990	COG3134	Outer membrane lipoprotein
ND011_06995	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ND011_07000	COG4591	ABC-type transport system involved in lipoprotein release permease component
ND011_07010	COG4591	ABC-type transport system involved in lipoprotein release permease component
ND011_07030	COG2850	peptidyl-arginine hydroxylation
ND011_07035	COG2205	protein histidine kinase activity
ND011_07040	COG0745	RESPONSE REGULATOR receiver
ND011_07050	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ND011_07055	COG2915	High frequency lysogenization protein hflD homolog
ND011_07060	COG0482	sulfurtransferase activity
ND011_07070	COG1187	pseudouridine synthase activity
ND011_07075	COG0538	isocitrate dehydrogenase activity
ND011_07080	COG2771	luxR family
ND011_07085	COG3916	Acyl-homoserine-lactone synthase
ND011_07090	COG2723	6-phospho-beta-galactosidase activity
ND011_07100	COG0339	signal peptide processing
ND011_07105	COG0840	transmembrane signaling receptor activity
ND011_07130	COG0675	Transposase, IS605 OrfB family
ND011_07140	COG4565	transcriptional regulatory protein
ND011_07145	COG3290	protein histidine kinase activity
ND011_07150	COG0471	metal ion transport
ND011_07190	COG4977	sequence-specific DNA binding
ND011_07195	COG1702	phosphate starvation-inducible protein PhoH
ND011_07200	COG0387	Pfam Sodium calcium exchanger
ND011_07205	COG2375	cellular response to nickel ion
ND011_07210	COG3850	Histidine kinase
ND011_07220	COG1294	oxidase, subunit
ND011_07225	COG1271	oxidase subunit
ND011_07230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ND011_07235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ND011_07240	COG3138	arginine N-succinyltransferase
ND011_07250	COG3724	N-succinylarginine dihydrolase activity
ND011_07270	COG1228	amidohydrolase
ND011_07280	COG0402	S-adenosylhomocysteine deaminase activity
ND011_07300	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
ND011_07305	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ND011_07310	COG3383	formate dehydrogenase (NAD+) activity
ND011_07315	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND011_07320	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
ND011_07330	COG3260	NADH ubiquinone oxidoreductase 20
ND011_07335	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ND011_07340	COG3261	NADH dehydrogenase
ND011_07340	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
ND011_07345	COG0650	Formate hydrogenlyase subunit 4
ND011_07350	COG0651	ATP synthesis coupled electron transport
ND011_07355	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND011_07365	COG0375	protein maturation
ND011_07370	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ND011_07375	COG0298	carbon dioxide binding
ND011_07380	COG0409	Hydrogenase expression formation protein
ND011_07385	COG0309	Hydrogenase expression formation protein (HypE)
ND011_07420	COG2207	Transcriptional regulator
ND011_07420	COG3708	Transcriptional regulator
ND011_07425	COG0012	GTP binding
ND011_07435	COG0193	aminoacyl-tRNA hydrolase activity
ND011_07445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ND011_07455	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
ND011_07460	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ND011_07465	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ND011_07470	COG2890	protein-(glutamine-N5) methyltransferase activity
ND011_07485	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ND011_07490	COG0659	secondary active sulfate transmembrane transporter activity
ND011_07495	COG3706	GGDEF domain
ND011_07520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ND011_07530	COG3381	protein complex oligomerization
ND011_07550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ND011_07560	COG0673	inositol 2-dehydrogenase activity
ND011_07565	COG0728	peptidoglycan biosynthetic process
ND011_07590	COG3102	Protein conserved in bacteria
ND011_07595	COG3142	Participates in the control of copper homeostasis
ND011_07610	COG3788	relative of glutathione S-transferase, MAPEG superfamily
ND011_07615	COG1801	Protein of unknown function DUF72
ND011_07625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ND011_07630	COG0494	nUDIX hydrolase
ND011_07640	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ND011_07650	COG2255	four-way junction helicase activity
ND011_07655	COG3104	oligopeptide transport
ND011_07660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ND011_07665	COG1121	(ABC) transporter
ND011_07670	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ND011_07675	COG0739	heme binding
ND011_07680	COG1560	Kdo2-lipid A biosynthetic process
ND011_07685	COG0469	pyruvate kinase activity
ND011_07690	COG1737	Transcriptional regulator
ND011_07695	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ND011_07700	COG0800	Aldolase
ND011_07710	COG2076	Multidrug Resistance protein
ND011_07715	COG0251	oxidation-reduction process
ND011_07720	COG1199	ATP-dependent helicase activity
ND011_07725	COG1214	PFAM Peptidase M22, glycoprotease
ND011_07730	COG3065	identical protein binding
ND011_07735	COG0318	PFAM AMP-dependent synthetase and ligase
ND011_07740	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ND011_07745	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
ND011_07750	COG2894	cell division
ND011_07755	COG0850	regulation of cytokinetic process
ND011_07760	COG3100	YcgL domain-containing protein
ND011_07765	COG0179	Fumarylacetoacetate (FAA) hydrolase
ND011_07770	COG2983	Belongs to the UPF0260 family
ND011_07790	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ND011_07800	COG2719	SpoVR family
ND011_07805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ND011_07810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ND011_07815	COG2814	Major facilitator Superfamily
ND011_07825	COG2200	EAL domain
ND011_07825	COG2202	Pas domain
ND011_07825	COG2199	diguanylate cyclase activity
ND011_07845	COG2718	Belongs to the UPF0229 family
ND011_07850	COG2766	serine protein kinase
ND011_07860	COG3713	MltA-interacting MipA family protein
ND011_07865	COG2194	sulfuric ester hydrolase activity
ND011_07880	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ND011_07885	COG3139	Protein of unknown function (DUF1315)
ND011_07890	COG1335	isochorismatase
ND011_07895	COG0252	asparaginase activity
ND011_07900	COG0616	signal peptide processing
ND011_07905	COG0778	Nitroreductase
ND011_07915	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ND011_07925	COG0494	nUDIX hydrolase
ND011_07930	COG0708	Exodeoxyribonuclease III
ND011_07960	COG0788	formyltetrahydrofolate deformylase activity
ND011_07970	COG1752	Esterase of the alpha-beta hydrolase superfamily
ND011_07975	COG0745	RESPONSE REGULATOR receiver
ND011_07995	COG1454	alcohol dehydrogenase
ND011_07995	COG1012	belongs to the aldehyde dehydrogenase family
ND011_08005	COG2095	MarC family integral membrane protein
ND011_08010	COG4166	transmembrane transport
ND011_08025	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ND011_08040	COG3099	Belongs to the UPF0263 family
ND011_08045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ND011_08065	COG2350	Protein conserved in bacteria
ND011_08080	COG3710	Transcriptional regulator
ND011_08115	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ND011_08140	COG0727	PFAM Uncharacterised protein family (UPF0153)
ND011_08145	COG3047	cAMP biosynthetic process
ND011_08160	COG0133	tryptophan synthase activity
ND011_08165	COG0134	indole-3-glycerol-phosphate synthase activity
ND011_08165	COG0135	phosphoribosylanthranilate isomerase activity
ND011_08175	COG0512	Glutamine amidotransferase of anthranilate synthase
ND011_08185	COG0613	PHP domain protein
ND011_08190	COG0009	L-threonylcarbamoyladenylate synthase
ND011_08210	COG1187	pseudouridine synthase activity
ND011_08220	COG1028	Short-chain dehydrogenase reductase Sdr
ND011_08225	COG0616	signal peptide processing
ND011_08240	COG0583	DNA-binding transcription factor activity
ND011_08255	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ND011_08265	COG0671	phosphoesterase, PA-phosphatase related
ND011_08270	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
ND011_08275	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
ND011_08295	COG0023	Translation Initiation Factor
ND011_08305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ND011_08310	COG5001	Diguanylate cyclase
ND011_08310	COG5002	protein histidine kinase activity
ND011_08310	COG3447	MASE1 domain protein
ND011_08315	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
ND011_08320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ND011_08330	COG4659	FMN binding
ND011_08340	COG2207	Transcriptional regulator
ND011_08340	COG3708	Transcriptional regulator
ND011_08355	COG4657	Part of a membrane complex involved in electron transport
ND011_08365	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ND011_08375	COG0673	inositol 2-dehydrogenase activity
ND011_08380	COG0385	Bile acid
ND011_08385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ND011_08390	COG5339	Protein conserved in bacteria
ND011_08395	COG1482	cell wall glycoprotein biosynthetic process
ND011_08400	COG0114	fumarate hydratase activity
ND011_08410	COG1940	carbohydrate kinase activity
ND011_08415	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ND011_08435	COG1742	UPF0060 membrane protein
ND011_08440	COG4221	oxidoreductase activity
ND011_08445	COG3023	N-Acetylmuramoyl-L-alanine amidase
ND011_08465	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ND011_08505	COG1011	Hydrolase
ND011_08515	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
ND011_08520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ND011_08525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ND011_08530	COG0589	response to stress
ND011_08560	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ND011_08565	COG3623	hexulose-6-phosphate isomerase
ND011_08570	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ND011_08575	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ND011_08585	COG0531	amino acid
ND011_08595	COG0745	RESPONSE REGULATOR receiver
ND011_08600	COG2205	protein histidine kinase activity
ND011_08615	COG2207	Transcriptional regulator
ND011_08620	COG1881	PFAM PEBP family protein
ND011_08630	COG3591	Belongs to the peptidase S1B family
ND011_08635	COG1643	Atp-dependent helicase
ND011_08640	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ND011_08645	COG3784	Protein of unknown function (DUF1318)
ND011_08660	COG2911	Protein conserved in bacteria
ND011_08665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ND011_08670	COG3187	Heat shock protein
ND011_08675	COG3042	response to heat
ND011_08680	COG1285	pathogenesis
ND011_08690	COG0674	pyruvate-flavodoxin oxidoreductase activity
ND011_08690	COG1013	pyruvate-flavodoxin oxidoreductase activity
ND011_08690	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ND011_08690	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ND011_08705	COG4166	transmembrane transport
ND011_08710	COG2866	Carboxypeptidase
ND011_08715	COG4948	Mandelate Racemase Muconate Lactonizing
ND011_08720	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ND011_08730	COG5642	Protein of unknown function (DUF2384)
ND011_08735	COG5654	RES domain protein
ND011_08740	COG3768	UPF0283 membrane protein
ND011_08745	COG3106	COG3106 Predicted ATPase
ND011_08755	COG1983	PspC domain protein
ND011_08765	COG1842	Phage shock protein A
ND011_08770	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ND011_08785	COG4166	transmembrane transport
ND011_08795	COG4171	peptide transport system, permease
ND011_08800	COG4172	Belongs to the ABC transporter superfamily
ND011_08805	COG4172	Belongs to the ABC transporter superfamily
ND011_08815	COG3104	oligopeptide transport
ND011_08825	COG0484	heat shock protein binding
ND011_08870	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ND011_08875	COG3133	Outer membrane lipoprotein
ND011_08880	COG1846	Transcriptional regulator
ND011_08890	COG4989	oxidoreductase activity
ND011_08895	COG3313	Fe-S protein
ND011_08900	COG2194	sulfuric ester hydrolase activity
ND011_08905	COG1309	transcriptional regulator
ND011_08910	COG1902	pentaerythritol trinitrate reductase activity
ND011_08925	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ND011_08930	COG0791	NLP P60 protein
ND011_08935	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ND011_08945	COG1609	Transcriptional regulator
ND011_08950	COG0583	DNA-binding transcription factor activity
ND011_08955	COG2814	Major facilitator Superfamily
ND011_08960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ND011_08965	COG0307	riboflavin synthase, alpha
ND011_09000	COG1376	ErfK ybiS ycfS ynhG family protein
ND011_09000	COG1388	LysM domain
ND011_09005	COG2166	iron-sulfur cluster assembly
ND011_09015	COG0719	Fe-S assembly protein
ND011_09020	COG0396	ATPase activity
ND011_09025	COG0719	Fe-S assembly protein
ND011_09030	COG0316	Belongs to the HesB IscA family
ND011_09035	COG2050	protein possibly involved in aromatic compounds catabolism
ND011_09040	COG0277	FAD linked oxidase domain protein
ND011_09040	COG0247	lactate metabolic process
ND011_09045	COG0628	permease
ND011_09055	COG0574	Belongs to the PEP-utilizing enzyme family
ND011_09055	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ND011_09060	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ND011_09065	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ND011_09075	COG4771	TonB-dependent receptor
ND011_09080	COG3720	iron ion transport
ND011_09085	COG4558	Periplasmic binding protein
ND011_09090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ND011_09095	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ND011_09105	COG0095	Lipoate-protein ligase
ND011_09110	COG0791	NLP P60 protein
ND011_09115	COG2076	Multidrug Resistance protein
ND011_09120	COG2076	Multidrug Resistance protein
ND011_09125	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
ND011_09140	COG0463	Glycosyl transferase, family 2
ND011_09145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ND011_09155	COG4139	cobalamin transport
ND011_09200	COG2184	nucleotidyltransferase activity
ND011_09215	COG2314	TM2 domain
ND011_09220	COG0776	regulation of translation
ND011_09290	COG0803	Belongs to the bacterial solute-binding protein 9 family
ND011_09295	COG1121	(ABC) transporter
ND011_09300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ND011_09305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ND011_09310	COG3001	Fructosamine kinase
ND011_09320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ND011_09325	COG1988	membrane-bound metal-dependent
ND011_09330	COG1823	symporter activity
ND011_09335	COG3023	N-Acetylmuramoyl-L-alanine amidase
ND011_09345	COG2814	Major facilitator Superfamily
ND011_09355	COG0501	Belongs to the peptidase M48B family
ND011_09360	COG0793	Belongs to the peptidase S41A family
ND011_09370	COG1956	GAF domain-containing protein
ND011_09375	COG2995	paraquat-inducible protein a
ND011_09380	COG3008	intermembrane lipid transfer
ND011_09385	COG4251	negative regulation of phosphorylation
ND011_09385	COG2203	Gaf domain
ND011_09385	COG5001	Diguanylate cyclase
ND011_09385	COG3706	GGDEF domain
ND011_09595	COG3772	lysozyme
ND011_09645	COG1674	ftsk spoiiie
ND011_09645	COG1178	ABC-type Fe3 transport system permease component
ND011_09765	COG1276	copper resistance
ND011_09770	COG2372	response to copper ion
ND011_09775	COG1528	Iron-storage protein
ND011_09795	COG1770	oligopeptidase
ND011_09805	COG3097	Belongs to the UPF0267 family
ND011_09810	COG3141	response to X-ray
ND011_09815	COG0513	Belongs to the DEAD box helicase family
ND011_09835	COG0494	nUDIX hydrolase
ND011_09840	COG1760	l-serine dehydratase
ND011_09845	COG1253	flavin adenine dinucleotide binding
ND011_09850	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND011_09850	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND011_09855	COG3715	PTS system
ND011_09860	COG3716	PTS system mannose fructose sorbose family IID component
ND011_09865	COG4811	Protein of unknown function (DUF986)
ND011_09870	COG1971	Probably functions as a manganese efflux pump
ND011_09890	COG1960	acyl-CoA dehydrogenase activity
ND011_09900	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ND011_09930	COG2226	methyltransferase
ND011_09935	COG0768	penicillin binding
ND011_09940	COG1496	oxidoreductase activity
ND011_09960	COG1113	amino acid transport
ND011_09995	COG2207	Transcriptional regulator
ND011_10015	COG1132	(ABC) transporter
ND011_10025	COG2203	Gaf domain
ND011_10025	COG3706	GGDEF domain
ND011_10025	COG4251	negative regulation of phosphorylation
ND011_10025	COG5001	Diguanylate cyclase
ND011_10045	COG1181	Belongs to the D-alanine--D-alanine ligase family
ND011_10065	COG1278	Cold shock
ND011_10070	COG1278	Cold shock
ND011_10075	COG1278	Cold shock
ND011_10090	COG1917	Cupin 2, conserved barrel domain protein
ND011_10090	COG2169	Transcriptional regulator
ND011_10095	COG1447	Phosphotransferase system cellobiose-specific component IIA
ND011_10100	COG2723	6-phospho-beta-galactosidase activity
ND011_10105	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ND011_10110	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ND011_10115	COG1187	pseudouridine synthase activity
ND011_10125	COG3122	Protein conserved in bacteria
ND011_10130	COG1757	Na H antiporter
ND011_10145	COG2235	arginine
ND011_10160	COG0076	glutamate decarboxylase activity
ND011_10165	COG0531	amino acid
ND011_10200	COG2153	protein acetylation
ND011_10205	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ND011_10235	COG0840	transmembrane signaling receptor activity
ND011_10240	COG2801	Transposase and inactivated derivatives
ND011_10260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ND011_10265	COG0322	excinuclease ABC activity
ND011_10270	COG2197	response regulator
ND011_10295	COG1113	amino acid transport
ND011_10305	COG0531	amino acid
ND011_10310	COG3710	Transcriptional regulator
ND011_10315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ND011_10320	COG0506	proline dehydrogenase activity
ND011_10320	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ND011_10320	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ND011_10325	COG1126	abc transporter atp-binding protein
ND011_10330	COG0765	amino acid transport
ND011_10335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND011_10340	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ND011_10350	COG1191	sigma factor activity
ND011_10390	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ND011_10395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ND011_10410	COG1677	Flagellar hook-basal body complex protein FliE
ND011_10420	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ND011_10425	COG1317	bacterial-type flagellum organization
ND011_10430	COG1157	protein secretion by the type III secretion system
ND011_10445	COG1580	Controls the rotational direction of flagella during chemotaxis
ND011_10525	COG1558	bacterial-type flagellum-dependent cell motility
ND011_10530	COG1815	bacterial-type flagellum-dependent cell motility
ND011_10540	COG2747	anti-sigma28 factor FlgM
ND011_10545	COG3418	PFAM FlgN family protein
ND011_10555	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ND011_10560	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ND011_10565	COG4935	Belongs to the peptidase S8 family
ND011_10565	COG1404	Belongs to the peptidase S8 family
ND011_10570	COG2197	response regulator
ND011_10585	COG3188	usher protein
ND011_10590	COG3121	Chaperone
ND011_10600	COG3539	Fimbrial protein
ND011_10630	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
ND011_10635	COG0745	RESPONSE REGULATOR receiver
ND011_10645	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ND011_10650	COG0840	transmembrane signaling receptor activity
ND011_10655	COG0840	transmembrane signaling receptor activity
ND011_10660	COG0835	chemotaxis
ND011_10665	COG0643	Histidine kinase
ND011_10665	COG2198	Histidine kinase
ND011_10670	COG1360	Flagellar Motor Protein
ND011_10690	COG0589	response to stress
ND011_10695	COG1285	pathogenesis
ND011_10700	COG0840	transmembrane signaling receptor activity
ND011_10720	COG1609	Transcriptional regulator
ND011_10730	COG0604	alcohol dehydrogenase
ND011_10730	COG1028	Short-chain dehydrogenase reductase Sdr
ND011_10730	COG3321	synthase
ND011_10765	COG0582	viral genome integration into host DNA
ND011_10780	COG3423	Transcriptional regulator
ND011_10815	COG3451	type IV secretory pathway VirB4
ND011_10835	COG3736	Type IV secretory pathway, component VirB8
ND011_10850	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
ND011_10865	COG4227	nucleotidyltransferase activity
ND011_10925	COG0471	metal ion transport
ND011_10940	COG3051	citrate lyase alpha subunit
ND011_10945	COG2301	Belongs to the HpcH HpaI aldolase family
ND011_10950	COG3052	prosthetic group binding
ND011_10955	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
ND011_10960	COG3290	protein histidine kinase activity
ND011_10965	COG4565	transcriptional regulatory protein
ND011_10980	COG2271	Major facilitator Superfamily
ND011_10985	COG1840	ABC-type Fe3 transport system, periplasmic component
ND011_10995	COG3842	ATPase activity
ND011_11015	COG1289	transmembrane transporter activity
ND011_11025	COG2925	Exonuclease
ND011_11030	COG0531	amino acid
ND011_11035	COG4771	TonB-dependent receptor
ND011_11045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ND011_11055	COG0833	amino acid
ND011_11060	COG0583	DNA-binding transcription factor activity
ND011_11070	COG2855	membrane
ND011_11075	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ND011_11080	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
ND011_11080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND011_11080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ND011_11085	COG1105	Belongs to the carbohydrate kinase PfkB family
ND011_11100	COG3005	denitrification pathway
ND011_11105	COG0243	molybdopterin cofactor binding
ND011_11125	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ND011_11135	COG0246	Mannitol dehydrogenase
ND011_11145	COG0523	cobalamin synthesis protein
ND011_11150	COG0671	phosphoesterase, PA-phosphatase related
ND011_11155	COG0791	NLP P60 protein
ND011_11160	COG2200	EAL domain
ND011_11165	COG4166	transmembrane transport
ND011_11170	COG4174	ABC transporter (Permease)
ND011_11175	COG4239	(ABC) transporter, permease
ND011_11180	COG4172	Belongs to the ABC transporter superfamily
ND011_11190	COG2814	Major facilitator Superfamily
ND011_11195	COG1187	pseudouridine synthase activity
ND011_11200	COG1061	Type III restriction enzyme res subunit
ND011_11215	COG3082	Protein of unknown function (DUF1414)
ND011_11220	COG3083	sulfuric ester hydrolase activity
ND011_11245	COG3778	Protein conserved in bacteria
ND011_11250	COG3299	homolog of phage Mu protein gp47
ND011_11295	COG4386	tail sheath protein
ND011_11345	COG4626	Terminase
ND011_11345	COG1802	Transcriptional regulator
ND011_11370	COG1876	peptidase activity
ND011_11400	COG2815	serine threonine protein kinase
ND011_11400	COG0515	serine threonine protein kinase
ND011_11415	COG1403	HNH endonuclease
ND011_11430	COG4725	Belongs to the MT-A70-like family
ND011_11435	COG4626	Terminase
ND011_11435	COG1802	Transcriptional regulator
ND011_11470	COG5532	Uncharacterized conserved protein (DUF2303)
ND011_11475	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ND011_11525	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ND011_11530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ND011_11550	COG2223	nitrite transmembrane transporter activity
ND011_11555	COG0642	Histidine kinase
ND011_11555	COG2198	Histidine kinase
ND011_11565	COG0784	Response regulator, receiver
ND011_11565	COG2205	protein histidine kinase activity
ND011_11575	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ND011_11580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ND011_11590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ND011_11600	COG4574	serine-type endopeptidase inhibitor activity
ND011_11610	COG2246	polysaccharide biosynthetic process
ND011_11625	COG0814	amino acid
ND011_11650	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
ND011_11655	COG0596	Alpha beta hydrolase
ND011_11660	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
ND011_11665	COG1169	isochorismate synthase
ND011_11670	COG4575	ribosome binding
ND011_11685	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ND011_11690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ND011_11700	COG0839	Belongs to the complex I subunit 6 family
ND011_11705	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ND011_11710	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ND011_11715	COG1034	ATP synthesis coupled electron transport
ND011_11735	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ND011_11740	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ND011_11745	COG0583	DNA-binding transcription factor activity
ND011_11750	COG0436	Aminotransferase
ND011_11755	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ND011_11760	COG0471	metal ion transport
ND011_11760	COG0490	domain, Protein
ND011_11770	COG3013	Belongs to the UPF0304 family
ND011_11775	COG3092	negative regulation of chromosome organization
ND011_11785	COG0280	phosphate acetyltransferase
ND011_11785	COG0857	belongs to the CobB CobQ family
ND011_11790	COG1609	Transcriptional regulator
ND011_11805	COG3037	sugar-specific permease SgaT UlaA
ND011_11810	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ND011_11815	COG0622	Phosphoesterase
ND011_11830	COG0625	glutathione transferase activity
ND011_11835	COG1090	epimerase
ND011_11845	COG4160	amino acid transport
ND011_11850	COG4215	(ABC) transporter
ND011_11865	COG0163	prenyltransferase activity
ND011_11870	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ND011_11875	COG1286	toxin biosynthetic process
ND011_11880	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
ND011_11885	COG0285	dihydrofolate synthase activity
ND011_11895	COG0586	Pfam SNARE associated Golgi protein
ND011_11905	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ND011_11930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ND011_11935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ND011_11965	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ND011_11980	COG3101	peptidyl-lysine hydroxylation
ND011_11985	COG0730	response to heat
ND011_11990	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ND011_12000	COG2890	protein-(glutamine-N5) methyltransferase activity
ND011_12005	COG2840	Smr protein MutS2
ND011_12010	COG2062	phosphohistidine phosphatase, SixA
ND011_12015	COG1250	3-hydroxyacyl-CoA dehydrogenase
ND011_12015	COG1024	Enoyl-CoA hydratase
ND011_12020	COG0183	Belongs to the thiolase family
ND011_12025	COG3691	Protein conserved in bacteria
ND011_12040	COG4235	cytochrome complex assembly
ND011_12040	COG3088	subunit of a heme lyase
ND011_12045	COG3088	subunit of a heme lyase
ND011_12045	COG4235	cytochrome complex assembly
ND011_12050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ND011_12055	COG1138	Cytochrome C-type biogenesis protein
ND011_12060	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ND011_12065	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ND011_12070	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ND011_12075	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ND011_12090	COG0582	viral genome integration into host DNA
ND011_12095	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ND011_12150	COG2824	Alkylphosphonate utilization operon protein PhnA
ND011_12155	COG2951	lytic endotransglycosylase activity
ND011_12160	COG1598	PFAM Uncharacterised protein family UPF0150
ND011_12170	COG3038	cytochrome b561
ND011_12175	COG0436	Aminotransferase
ND011_12185	COG3275	phosphorelay sensor kinase activity
ND011_12190	COG3279	Response regulator of the LytR AlgR family
ND011_12195	COG2223	nitrite transmembrane transporter activity
ND011_12200	COG0837	glucose binding
ND011_12220	COG1914	H( )-stimulated, divalent metal cation uptake system
ND011_12225	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ND011_12290	COG3530	Putative quorum-sensing-regulated virulence factor
ND011_12295	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ND011_12305	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
ND011_12315	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND011_12330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ND011_12340	COG4208	sulfate ABC transporter
ND011_12345	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ND011_12350	COG4150	thiosulfate binding
ND011_12360	COG1737	Transcriptional regulator
ND011_12365	COG2731	YhcH YjgK YiaL family protein
ND011_12380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ND011_12385	COG2837	iron assimilation
ND011_12395	COG3111	PFAM Bacterial OB fold (BOF) protein
ND011_12455	COG1671	Belongs to the UPF0178 family
ND011_12460	COG0281	malic enzyme
ND011_12460	COG0280	phosphate acetyltransferase
ND011_12465	COG0494	nUDIX hydrolase
ND011_12470	COG3005	denitrification pathway
ND011_12475	COG3043	anaerobic respiration
ND011_12480	COG0243	molybdopterin cofactor binding
ND011_12485	COG3062	negative regulation of establishment of protein localization
ND011_12490	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND011_12490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND011_12495	COG2197	response regulator
ND011_12505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ND011_12515	COG1605	Chorismate mutase
ND011_12520	COG1393	Belongs to the ArsC family
ND011_12525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ND011_12530	COG1876	peptidase activity
ND011_12540	COG0400	carboxylic ester hydrolase activity
ND011_12560	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
ND011_12565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ND011_12570	COG2716	regulation of RNA biosynthetic process
ND011_12575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ND011_12580	COG0628	permease
ND011_12585	COG4783	chaperone-mediated protein folding
ND011_12590	COG1393	Belongs to the ArsC family
ND011_12595	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ND011_12600	COG2233	PERMEase
ND011_12605	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ND011_12610	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ND011_12615	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ND011_12620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ND011_12630	COG0581	inorganic phosphate transmembrane transporter activity
ND011_12635	COG0573	inorganic phosphate transmembrane transporter activity
ND011_12640	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ND011_12655	COG2239	Acts as a magnesium transporter
ND011_12660	COG0443	Heat shock 70 kDa protein
ND011_12670	COG3121	Chaperone
ND011_12690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ND011_12700	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ND011_12705	COG0477	Major facilitator Superfamily
ND011_12710	COG2205	protein histidine kinase activity
ND011_12715	COG0745	RESPONSE REGULATOR receiver
ND011_12720	COG3422	double-strand break repair
ND011_12725	COG0826	peptidase U32
ND011_12730	COG1597	lipid kinase activity
ND011_12745	COG0351	phosphomethylpyrimidine kinase
ND011_12760	COG0519	Catalyzes the synthesis of GMP from XMP
ND011_12760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ND011_12765	COG0517	IMP dehydrogenase activity
ND011_12765	COG0516	GMP reductase activity
ND011_12770	COG1570	exodeoxyribonuclease VII activity
ND011_12775	COG1645	bacterial-type flagellum-dependent swarming motility
ND011_12785	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ND011_12790	COG2976	Protein conserved in bacteria
ND011_12795	COG0124	histidyl-tRNA synthetase
ND011_12815	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ND011_12830	COG4953	penicillin-binding protein 1C
ND011_12835	COG2373	Large extracellular alpha-helical protein
ND011_12850	COG2975	iron-sulfur cluster assembly
ND011_12855	COG0633	Ferredoxin
ND011_12860	COG0443	Heat shock 70 kDa protein
ND011_12875	COG0822	iron-sulfur transferase activity
ND011_12885	COG1959	2 iron, 2 sulfur cluster binding
ND011_12890	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
ND011_12900	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ND011_12905	COG3683	transport system, periplasmic component
ND011_12910	COG3711	transcriptional antiterminator
ND011_12915	COG2814	Major facilitator Superfamily
ND011_12925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ND011_12925	COG1017	nitric oxide dioxygenase activity
ND011_12930	COG2188	Transcriptional regulator
ND011_12940	COG3457	Alanine racemase
ND011_12945	COG1735	metal-dependent hydrolase with the TIM-barrel fold
ND011_12960	COG0347	Belongs to the P(II) protein family
ND011_12965	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ND011_12965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ND011_12970	COG2204	response regulator
ND011_12975	COG3170	Tfp pilus assembly protein FimV
ND011_12980	COG2205	protein histidine kinase activity
ND011_12995	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
ND011_13005	COG0560	Phosphoserine phosphatase
ND011_13010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND011_13010	COG1263	PTS System
ND011_13020	COG1737	Transcriptional regulator
ND011_13025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ND011_13035	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ND011_13045	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ND011_13060	COG0481	GTPase activity
ND011_13065	COG3086	response to oxidative stress
ND011_13075	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
ND011_13085	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ND011_13095	COG0513	Belongs to the DEAD box helicase family
ND011_13110	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
ND011_13120	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ND011_13125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ND011_13130	COG0497	DNA recombination
ND011_13135	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ND011_13145	COG2867	negative regulation of translational initiation
ND011_13150	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ND011_13160	COG0582	viral genome integration into host DNA
ND011_13190	COG3596	GTP binding
ND011_13195	COG2378	regulation of single-species biofilm formation
ND011_13205	COG2378	regulation of single-species biofilm formation
ND011_13230	COG2003	Belongs to the UPF0758 family
ND011_13285	COG3121	Chaperone
ND011_13290	COG3188	usher protein
ND011_13315	COG0583	DNA-binding transcription factor activity
ND011_13390	COG1069	ribulokinase activity
ND011_13400	COG1172	Belongs to the binding-protein-dependent transport system permease family
ND011_13405	COG1129	ABC transporter
ND011_13425	COG1620	l-lactate permease
ND011_13430	COG1304	FMN binding
ND011_13435	COG0579	oxidoreductase
ND011_13440	COG1278	Cold shock
ND011_13470	COG1780	Probably involved in ribonucleotide reductase function
ND011_13475	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ND011_13485	COG4175	Glycine betaine
ND011_13490	COG4176	ABC-type proline glycine betaine transport system permease component
ND011_13495	COG2113	Glycine betaine
ND011_13505	COG2814	Major facilitator Superfamily
ND011_13510	COG1846	Transcriptional regulator
ND011_13520	COG1566	PFAM secretion protein HlyD family protein
ND011_13525	COG2814	Major facilitator Superfamily
ND011_13530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ND011_13535	COG3118	belongs to the thioredoxin family
ND011_13540	COG3148	PFAM DTW domain containing protein
ND011_13545	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ND011_13545	COG1042	CoA-binding domain protein
ND011_13545	COG0045	succinate-CoA ligase (ADP-forming) activity
ND011_13550	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ND011_13555	COG5544	Lipoprotein
ND011_13580	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ND011_13590	COG2011	ABC-type metal ion transport system permease component
ND011_13595	COG1464	Belongs to the NlpA lipoprotein family
ND011_13605	COG1720	tRNA m6t6A37 methyltransferase activity
ND011_13610	COG0442	prolyl-tRNA aminoacylation
ND011_13615	COG3015	lipoprotein NlpE involved in copper resistance
ND011_13625	COG4681	YaeQ
ND011_13635	COG4568	rho-dependent transcription termination
ND011_13650	COG0346	lactoylglutathione lyase activity
ND011_13665	COG0825	malonyl-CoA metabolic process
ND011_13670	COG0587	DNA-directed DNA polymerase activity
ND011_13675	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ND011_13695	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ND011_13700	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
ND011_13710	COG0750	zinc metalloprotease
ND011_13715	COG0575	Belongs to the CDS family
ND011_13735	COG0528	UMP kinase activity
ND011_13740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ND011_13755	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ND011_13760	COG2171	N-acyltransferase activity
ND011_13775	COG0564	pseudouridine synthase activity
ND011_13780	COG3098	single-species biofilm formation
ND011_13795	COG1611	Belongs to the LOG family
ND011_13805	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
ND011_13810	COG2363	Small membrane protein
ND011_13815	COG0583	DNA-binding transcription factor activity
ND011_13825	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ND011_13830	COG2166	iron-sulfur cluster assembly
ND011_13835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ND011_13840	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ND011_13860	COG0860	N-Acetylmuramoyl-L-alanine amidase
ND011_13865	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ND011_13865	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ND011_13870	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ND011_13875	COG1074	ATP-dependent DNA helicase activity
ND011_13880	COG1025	Belongs to the peptidase M16 family
ND011_13885	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
ND011_13890	COG4967	type IV pilus modification protein PilV
ND011_13915	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ND011_13920	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
ND011_13930	COG3066	DNA modification
ND011_13935	COG0861	Integral membrane protein TerC family
ND011_13940	COG0667	Aldo Keto reductase
ND011_13945	COG0477	Major facilitator Superfamily
ND011_13950	COG0318	PFAM AMP-dependent synthetase and ligase
ND011_13950	COG0204	Acyl-transferase
ND011_13955	COG1609	Transcriptional regulator
ND011_13965	COG0583	DNA-binding transcription factor activity
ND011_13970	COG0583	DNA-binding transcription factor activity
ND011_14025	COG2165	general secretion pathway protein
ND011_14035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ND011_14065	COG1127	ABC transporter
ND011_14070	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ND011_14080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ND011_14090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ND011_14095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ND011_14100	COG4974	Belongs to the 'phage' integrase family
ND011_14105	COG0716	FMN binding
ND011_14115	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
ND011_14125	COG1272	protein, Hemolysin III
ND011_14145	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ND011_14150	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ND011_14155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ND011_14160	COG0006	proline dipeptidase activity
ND011_14170	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ND011_14180	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ND011_14185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ND011_14190	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ND011_14205	COG1279	arginine transmembrane transporter activity
ND011_14215	COG0191	fructose-bisphosphate aldolase activity
ND011_14220	COG0126	phosphoglycerate kinase activity
ND011_14225	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ND011_14230	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ND011_14240	COG1166	arginine decarboxylase activity
ND011_14245	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ND011_14260	COG0640	Transcriptional regulator
ND011_14265	COG3091	SprT-like family
ND011_14270	COG2356	endonuclease I
ND011_14275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ND011_14280	COG0189	ligase activity
ND011_14285	COG1678	Uncharacterized ACR, COG1678
ND011_14290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ND011_14295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ND011_14305	COG2805	Type II/IV secretion system protein
ND011_14310	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ND011_14315	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ND011_14320	COG0762	integral membrane protein
ND011_14325	COG1872	DUF167
ND011_14330	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ND011_14335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ND011_14350	COG3171	Protein conserved in bacteria
ND011_14360	COG1194	a g-specific adenine glycosylase
ND011_14365	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
ND011_14370	COG0741	lytic transglycosylase activity
ND011_14415	COG1105	Belongs to the carbohydrate kinase PfkB family
ND011_14420	COG1882	Formate acetyltransferase
ND011_14425	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ND011_14430	COG0814	amino acid
ND011_14445	COG1028	Short-chain dehydrogenase reductase Sdr
ND011_14450	COG1535	isochorismatase
ND011_14450	COG3433	isochorismatase activity
ND011_14455	COG1021	2,3-dihydroxybenzoate-AMP ligase
ND011_14460	COG1169	isochorismate synthase
ND011_14465	COG4592	Periplasmic binding protein
ND011_14475	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ND011_14480	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ND011_14485	COG1120	ATPase activity
ND011_14495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ND011_14500	COG3251	PFAM MbtH domain protein
ND011_14510	COG4774	siderophore transport
ND011_14515	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ND011_14540	COG4964	Belongs to the GSP D family
ND011_14600	COG0848	biopolymer transport protein
ND011_14605	COG0811	peptide transport
ND011_14610	COG0626	cystathionine gamma-synthase activity
ND011_14615	COG0586	Pfam SNARE associated Golgi protein
ND011_14620	COG2207	Transcriptional regulator
ND011_14625	COG1979	alcohol dehydrogenase
ND011_14630	COG0656	L-ascorbic acid biosynthetic process
ND011_14640	COG2132	Multicopper oxidase
ND011_14655	COG2249	NAD(P)H dehydrogenase (quinone) activity
ND011_14660	COG0583	DNA-binding transcription factor activity
ND011_14665	COG0187	DNA topoisomerase II activity
ND011_14670	COG3150	esterase
ND011_14675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
ND011_14680	COG3151	Protein conserved in bacteria
ND011_14685	COG0494	nUDIX hydrolase
ND011_14690	COG1538	Outer membrane efflux protein
ND011_14695	COG5463	Belongs to the UPF0441 family
ND011_14700	COG0754	glutathionylspermidine amidase activity
ND011_14705	COG3384	dioxygenase
ND011_14710	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ND011_14725	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ND011_14725	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ND011_14735	COG3025	triphosphatase activity
ND011_14740	COG4991	sh3 domain protein
ND011_14745	COG0617	tRNA 3'-terminal CCA addition
ND011_14750	COG1968	undecaprenyl-diphosphatase activity
ND011_14755	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ND011_14760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ND011_14765	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ND011_14770	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ND011_14775	COG0358	DNA primase activity
ND011_14805	COG1028	Short-chain dehydrogenase reductase Sdr
ND011_14835	COG0463	Glycosyl transferase, family 2
ND011_14870	COG3210	domain, Protein
ND011_14875	COG3210	domain, Protein
ND011_14885	COG2831	hemolysin activation secretion protein
ND011_14890	COG0446	pyridine nucleotide-disulphide oxidoreductase
ND011_14890	COG1902	pentaerythritol trinitrate reductase activity
ND011_14905	COG1451	nucleotide metabolic process
ND011_14910	COG0673	inositol 2-dehydrogenase activity
ND011_14915	COG0861	Integral membrane protein TerC family
ND011_14920	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
ND011_14930	COG2721	sulfolactate sulfo-lyase activity
ND011_14945	COG2271	Major facilitator Superfamily
ND011_14960	COG0586	Pfam SNARE associated Golgi protein
ND011_14975	COG4575	ribosome binding
ND011_14980	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
ND011_14990	COG2259	Doxx family
ND011_14995	COG0583	DNA-binding transcription factor activity
ND011_15000	COG1741	Belongs to the pirin family
ND011_15015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ND011_15030	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ND011_15035	COG2823	Periplasmic or secreted lipoprotein
ND011_15040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ND011_15045	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
ND011_15050	COG5002	protein histidine kinase activity
ND011_15050	COG2198	Histidine kinase
ND011_15050	COG0784	Response regulator, receiver
ND011_15055	COG1242	4 iron, 4 sulfur cluster binding
ND011_15060	COG0070	glutamate synthase
ND011_15060	COG0069	glutamate synthase activity
ND011_15060	COG0067	glutamate synthase
ND011_15065	COG0493	'glutamate synthase
ND011_15075	COG2969	positive regulation of protein catabolic process
ND011_15080	COG0625	glutathione transferase activity
ND011_15085	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ND011_15090	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ND011_15095	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ND011_15100	COG3105	Protein conserved in bacteria
ND011_15105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ND011_15115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ND011_15120	COG5007	Belongs to the BolA IbaG family
ND011_15125	COG3113	response to antibiotic
ND011_15130	COG2854	intermembrane phospholipid transfer
ND011_15135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
ND011_15140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ND011_15145	COG1127	ABC transporter
ND011_15150	COG0530	calcium, potassium:sodium antiporter activity
ND011_15155	COG0517	IMP dehydrogenase activity
ND011_15155	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ND011_15160	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ND011_15165	COG3117	lipopolysaccharide transmembrane transporter activity
ND011_15170	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
ND011_15175	COG1137	ATPase activity
ND011_15180	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ND011_15200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ND011_15205	COG0540	Belongs to the ATCase OTCase family
ND011_15210	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
ND011_15220	COG0366	Alpha amylase catalytic
ND011_15225	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ND011_15225	COG1263	PTS System
ND011_15235	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ND011_15245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ND011_15250	COG3783	Cytochrome b(562)
ND011_15255	COG0312	modulator of DNA gyrase
ND011_15260	COG3028	Belongs to the UPF0307 family
ND011_15265	COG2732	(Barnase) inhibitor
ND011_15270	COG4290	ribonuclease
ND011_15280	COG1289	transmembrane transporter activity
ND011_15285	COG1566	PFAM secretion protein HlyD family protein
ND011_15295	COG0583	DNA-binding transcription factor activity
ND011_15300	COG0312	modulator of DNA gyrase
ND011_15305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ND011_15310	COG3164	Protein of unknown function
ND011_15320	COG0424	maF-like protein
ND011_15325	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
ND011_15330	COG1792	Involved in formation and maintenance of cell shape
ND011_15335	COG1077	Cell shape determining protein MreB Mrl
ND011_15340	COG2199	diguanylate cyclase activity
ND011_15340	COG2200	EAL domain
ND011_15345	COG0604	alcohol dehydrogenase
ND011_15350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ND011_15355	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ND011_15365	COG0511	ligase activity, forming carbon-carbon bonds
ND011_15370	COG0439	Biotin carboxylase
ND011_15375	COG3924	membrane
ND011_15380	COG4145	pantothenate transmembrane transporter activity
ND011_15385	COG2264	protein methyltransferase activity
ND011_15390	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ND011_15395	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
ND011_15405	COG1560	Kdo2-lipid A biosynthetic process
ND011_15415	COG1346	cytolysis
ND011_15420	COG1380	Effector of murein hydrolase LrgA
ND011_15425	COG0583	DNA-binding transcription factor activity
ND011_15430	COG0025	NhaP-type Na H and K H
ND011_15435	COG2252	PERMEase
ND011_15450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ND011_15455	COG2315	Protein conserved in bacteria
ND011_15460	COG1448	Aminotransferase
ND011_15485	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ND011_15490	COG0735	belongs to the Fur family
ND011_15495	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ND011_15500	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
ND011_15505	COG2937	Belongs to the GPAT DAPAT family
ND011_15525	COG4580	involved in the transport of maltose and maltodextrins
ND011_15540	COG2182	Extracellular solute-binding protein
ND011_15545	COG1175	transmembrane transport
ND011_15550	COG3833	ABC-type maltose transport systems, permease component
ND011_15555	COG3223	Belongs to the PsiE family
ND011_15565	COG0527	aspartate kinase activity
ND011_15580	COG3328	transposase activity
ND011_15590	COG3328	transposase activity
ND011_15615	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ND011_15695	COG0583	DNA-binding transcription factor activity
ND011_15735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ND011_15775	COG0138	bifunctional purine biosynthesis protein purh
ND011_15780	COG0151	Belongs to the GarS family
ND011_15800	COG1515	deoxyribonuclease V activity
ND011_15805	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ND011_15810	COG2816	NAD+ diphosphatase activity
ND011_15815	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
ND011_15830	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ND011_15835	COG2104	thiamine diphosphate biosynthetic process
ND011_15840	COG2022	thiamine diphosphate biosynthetic process
ND011_15850	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ND011_15855	COG0085	RNA polymerase activity
ND011_15860	COG0222	ribosome binding
ND011_15865	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ND011_15875	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ND011_15880	COG0250	Participates in transcription elongation, termination and antitermination
ND011_15925	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ND011_15950	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
ND011_15955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ND011_15960	COG1739	Uncharacterized protein family UPF0029
ND011_15970	COG1024	Enoyl-CoA hydratase
ND011_15970	COG1250	3-hydroxyacyl-CoA dehydrogenase
ND011_15980	COG0543	2 iron, 2 sulfur cluster binding
ND011_15995	COG0250	Participates in transcription elongation, termination and antitermination
ND011_16010	COG0805	protein transport
ND011_16015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ND011_16020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ND011_16025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ND011_16030	COG3165	ubiquinone biosynthetic process from chorismate
ND011_16035	COG2226	methyltransferase
ND011_16040	COG1322	Protein conserved in bacteria
ND011_16045	COG0586	Pfam SNARE associated Golgi protein
ND011_16050	COG1966	Carbon starvation protein
ND011_16065	COG0412	Dienelactone hydrolase
ND011_16070	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ND011_16075	COG0583	DNA-binding transcription factor activity
ND011_16080	COG0697	spore germination
ND011_16090	COG0584	glycerophosphoryl diester phosphodiesterase
ND011_16100	COG0395	ABC-type sugar transport system, permease component
ND011_16105	COG1175	transmembrane transport
ND011_16110	COG1653	transport
ND011_16145	COG0410	ABC transporter
ND011_16155	COG4177	L-phenylalanine transmembrane transporter activity
ND011_16175	COG1929	Belongs to the glycerate kinase type-1 family
ND011_16180	COG2610	gluconate transmembrane transporter activity
ND011_16185	COG3835	regulator
ND011_16195	COG2177	Part of the ABC transporter FtsEX involved in
ND011_16200	COG2884	Cell division ATP-binding protein ftsE
ND011_16205	COG0552	protein localization to endoplasmic reticulum
ND011_16205	COG0552	protein localization to endoplasmic reticulum
ND011_16210	COG0742	ribosomal rna small subunit methyltransferase
ND011_16215	COG3776	membrane
ND011_16230	COG3714	YhhN family
ND011_16245	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ND011_16255	COG0247	lactate metabolic process
ND011_16265	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ND011_16275	COG2271	Major facilitator Superfamily
ND011_16280	COG0584	glycerophosphoryl diester phosphodiesterase
ND011_16285	COG0561	phosphatase activity
ND011_16290	COG2267	carboxylic ester hydrolase activity
ND011_16295	COG1280	lysine exporter protein (LysE YggA)
ND011_16300	COG0514	ATP-dependent DNA helicase (RecQ)
ND011_16305	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
ND011_16310	COG2050	protein possibly involved in aromatic compounds catabolism
ND011_16330	COG5564	TIM-barrel signal transduction protein
ND011_16335	COG5441	Belongs to the UPF0261 family
ND011_16345	COG0210	DNA helicase
ND011_16350	COG1011	Hydrolase
ND011_16355	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ND011_16360	COG3159	Protein conserved in bacteria
ND011_16365	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ND011_16370	COG5567	small periplasmic lipoprotein
ND011_16380	COG3072	Adenylate cyclase
ND011_16385	COG0181	hydroxymethylbilane synthase activity
ND011_16390	COG1587	Uroporphyrinogen-III synthase
ND011_16395	COG2959	enzyme of heme biosynthesis
ND011_16400	COG3071	HemY protein
ND011_16445	COG2244	polysaccharide biosynthetic process
ND011_16450	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ND011_16455	COG0456	acetyltransferase
ND011_16460	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
ND011_16465	COG1088	dTDP-glucose 4,6-dehydratase activity
ND011_16470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ND011_16475	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ND011_16480	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
ND011_16485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ND011_16490	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ND011_16495	COG3118	belongs to the thioredoxin family
ND011_16505	COG0248	Ppx GppA phosphatase
ND011_16515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ND011_16530	COG3397	chitin binding
ND011_16540	COG0129	dihydroxy-acid dehydratase activity
ND011_16550	COG3978	acetolactate synthase activity
ND011_16570	COG3085	chromosome segregation
ND011_16575	COG0583	DNA-binding transcription factor activity
ND011_16650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ND011_16660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ND011_16660	COG0678	peroxiredoxin activity
ND011_16665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ND011_16700	COG1629	transport
ND011_16705	COG0165	Argininosuccinate lyase
ND011_16710	COG0137	argininosuccinate synthase activity
ND011_16715	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ND011_16760	COG0460	homoserine dehydrogenase
ND011_16760	COG0527	aspartate kinase activity
ND011_16765	COG0626	cystathionine gamma-synthase activity
ND011_16770	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
ND011_16780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ND011_16785	COG1609	Transcriptional regulator
ND011_16790	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
ND011_16795	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ND011_16800	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ND011_16805	COG1575	Belongs to the MenA family. Type 1 subfamily
ND011_16810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ND011_16815	COG3074	FtsZ-dependent cytokinesis
ND011_16820	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ND011_16825	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ND011_16830	COG1494	fructose-1,6-bisphosphatase
ND011_16835	COG2814	Major facilitator Superfamily
ND011_16845	COG3152	Membrane
ND011_16860	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ND011_16870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ND011_16875	COG3678	ATP-independent chaperone mediated protein folding
ND011_16880	COG0745	RESPONSE REGULATOR receiver
ND011_16885	COG2205	protein histidine kinase activity
ND011_16890	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ND011_16895	COG1045	serine acetyltransferase
ND011_16900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ND011_16905	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ND011_16910	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ND011_16915	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ND011_16920	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ND011_16925	COG4942	peptidase
ND011_16930	COG2861	carbohydrate metabolic process
ND011_16945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ND011_16950	COG0859	PFAM glycosyl transferase family 9
ND011_16955	COG0859	PFAM glycosyl transferase family 9
ND011_16960	COG1519	Transferase
ND011_16980	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ND011_16985	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ND011_16990	COG2003	Belongs to the UPF0758 family
ND011_16995	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ND011_17000	COG0756	dUTP diphosphatase activity
ND011_17005	COG1309	transcriptional regulator
ND011_17010	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ND011_17015	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ND011_17020	COG1561	YicC-like family, N-terminal region
ND011_17035	COG5001	Diguanylate cyclase
ND011_17040	COG1024	Enoyl-CoA hydratase
ND011_17045	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ND011_17055	COG2860	membrane
ND011_17060	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ND011_17070	COG1758	RNA polymerase activity
ND011_17075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ND011_17080	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ND011_17085	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ND011_17090	COG0786	glutamate:sodium symporter activity
ND011_17095	COG2233	PERMEase
ND011_17100	COG2982	Protein involved in outer membrane biogenesis
ND011_17105	COG0456	acetyltransferase
ND011_17120	COG1011	Hydrolase
ND011_17135	COG3852	Histidine kinase
ND011_17145	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ND011_17155	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ND011_17160	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ND011_17160	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ND011_17165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ND011_17170	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ND011_17175	COG3084	Protein conserved in bacteria
ND011_17185	COG1763	Mo-molybdopterin cofactor biosynthetic process
ND011_17210	COG2186	Transcriptional regulator
ND011_17215	COG1609	Transcriptional regulator
ND011_17220	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ND011_17230	COG1172	Belongs to the binding-protein-dependent transport system permease family
ND011_17235	COG1129	ABC transporter
ND011_17240	COG1869	D-ribose catabolic process
ND011_17245	COG3158	transport of potassium into the cell
ND011_17250	COG0714	Associated with various cellular activities
ND011_17255	COG2425	protein containing a von Willebrand factor type A (vWA) domain
ND011_17265	COG2502	aspartate--ammonia ligase
ND011_17270	COG1522	sequence-specific DNA binding
ND011_17275	COG0716	FMN binding
ND011_17280	COG0445	tRNA wobble uridine modification
ND011_17285	COG0357	Ribosomal RNA small subunit methyltransferase G
ND011_17290	COG3312	ion transport
ND011_17295	COG0356	it plays a direct role in the translocation of protons across the membrane
ND011_17305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ND011_17315	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ND011_17320	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ND011_17330	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ND011_17345	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ND011_17350	COG0573	inorganic phosphate transmembrane transporter activity
ND011_17355	COG0581	inorganic phosphate transmembrane transporter activity
ND011_17365	COG0704	Plays a role in the regulation of phosphate uptake
ND011_17370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ND011_17375	COG0765	amino acid transport
ND011_17380	COG0765	amino acid transport
ND011_17385	COG2252	PERMEase
ND011_17390	COG0840	transmembrane signaling receptor activity
ND011_17400	COG3121	Chaperone
ND011_17415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ND011_17420	COG0706	membrane insertase activity
ND011_17430	COG0594	ribonuclease P activity
ND011_17435	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ND011_17490	COG4386	tail sheath protein
ND011_17515	COG4397	Mu-like prophage major head subunit gpT
ND011_17540	COG4383	Mu-like prophage protein gp29
ND011_17595	COG4382	Mu-like prophage protein Gp16
ND011_17660	COG3423	Transcriptional regulator
ND011_17825	COG2944	sequence-specific DNA binding
ND011_17895	COG1192	Involved in chromosome partitioning
ND011_17970	COG1454	alcohol dehydrogenase
ND011_18075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ND011_18090	COG0741	lytic transglycosylase activity
ND011_18105	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs