locus-tag class description BF17_00030 ENOG4105MDZ Transcriptional activator rfaH BF17_00095 ENOG4107QJE Chromosome Partitioning Protein BF17_00150 ENOG4105RT5 Toxic component of a toxin-antitoxin (TA) module. An mRNA interferase which has been reported to be translation- independent (PubMed 19690171, PubMed 19943910) and translation- dependent (PubMed 20041169). Cleavage has been reported to occur on either side of G in the sequence GCU (PubMed 19690171) but also after C in GC(A U) sequences (PubMed 19943910). There are only 14 genes in E.coli W3110 (and probably also MG1655) that do not have a GCU sequence and thus are resistant to the mRNA interferase activity. Overexpression causes cessation of cell growth and inhibits cell proliferation via inhibition of translation as well as increasing persister cell formation BF17_00155 ENOG4105WJ3 XRE family Transcriptional regulator BF17_00310 ENOG4105CZX twitching motility protein BF17_00335 ENOG4105K5T PilT protein BF17_00350 ENOG4107QHF type ii secretion system protein e BF17_00380 ENOG4108C80 FliB family BF17_00390 ENOG4105E2Z phosphate ABC transporter (Permease BF17_00395 ENOG4105C8U phosphate abc transporter BF17_00400 ENOG4105CUU Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity) BF17_00405 ENOG4105C9X ppx gppa phosphatase BF17_00415 ENOG4105CJW magnesium transporter BF17_00420 ENOG4105R8A Heat shock protein BF17_00445 ENOG4105EB3 Histidine kinase BF17_00450 ENOG4105E3W Two component transcriptional regulator (Winged helix family BF17_00455 ENOG4105KWI UPF0339 protein BF17_00460 ENOG4105CFP Peptidase U32 BF17_00475 ENOG4108ZGU inhibitor of vertebrate lysozyme BF17_00485 ENOG4105DWF phosphomethylpyrimidine kinase BF17_00525 ENOG4108WC9 type VI secretion system effector, hcp1 family BF17_00545 ENOG4105CP4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity) BF17_00565 ENOG4105CNE Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BF17_00570 ENOG4105N21 Membrane BF17_00610 ENOG4107F1U Beta/Gamma crystallin BF17_00620 ENOG4108MGN ATP-binding component of a transport system BF17_00625 ENOG4108MGN ATP-binding component of a transport system BF17_00630 ENOG4105YYA enhanced serine sensitivity protein SseB BF17_00640 ENOG4105WVQ Fe-S assembly protein IscX BF17_00645 ENOG4108ZIT Ferredoxin, 2FE-2S BF17_00665 ENOG4107XTC May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins BF17_00670 ENOG4105C3J Cysteine desulfurase BF17_00685 ENOG4105ECY inositol monophosphatase BF17_00690 ENOG4105D7X high-affinity nickel-transporter BF17_00695 ENOG41065CD Exported protein BF17_00700 ENOG4108MN2 Stationary phase inducible protein CsiE BF17_00705 ENOG4105D8G Major Facilitator superfamily BF17_00725 ENOG4108EGH Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BF17_00735 ENOG4108M21 BF17_00740 ENOG4108YZA Nitrogen regulatory protein pii BF17_00745 ENOG4105C4K Nad synthetase BF17_00760 ENOG4108SKK alpha helix protein BF17_00765 ENOG4107WP9 Histidine kinase BF17_00795 ENOG4108Z6B deaminase BF17_00800 ENOG4105HYY HAD superfamily (Subfamily IF) hydrolase, YfhB BF17_00810 ENOG4106G6Q Transcriptional regulator BF17_00815 ENOG4105K5D 4fe-4S ferredoxin iroN-sulfur binding BF17_00825 ENOG4105CSZ Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity) BF17_00845 ENOG4105C3F Signal peptidase i BF17_00860 ENOG4105WMJ Positive regulator of sigma E, RseC MucC BF17_00865 ENOG4105VQK sigma E regulatory protein, MucB RseB BF17_00870 ENOG41069PW sigma-e factor negative regulatory protein BF17_00880 ENOG4108IYU L-aspartate oxidase BF17_00890 ENOG4105C1J atp-dependent rna helicase BF17_00935 ENOG4107R7A Allophanate hydrolase subunit 2 BF17_00940 ENOG4105P4J Allophanate hydrolase, subunit 1 BF17_00945 ENOG4107QNR UPF0135 protein BF17_00950 ENOG4107RF4 Phosphodiesterase BF17_00955 ENOG4105CVP deoxyribo-dipyrimidine photolyase BF17_00960 ENOG4107SEY Conserved Protein BF17_00965 ENOG4105XIQ Protein of unknown function (DUF2517) BF17_00995 ENOG4105C08 Histidine kinase BF17_01010 ENOG4105EEX Two component transcriptional regulator (Winged helix family BF17_01040 ENOG4107QIX Phosphoglucomutase (EC 5.4.2.2 BF17_01065 ENOG4105EZV Transcriptional regulator BF17_01070 ENOG4105VCP PTS System BF17_01075 ENOG4105CK1 PTS System BF17_01080 ENOG4105VZJ PTS System BF17_01110 ENOG41086WQ Protein CrcB homolog BF17_01115 ENOG4107SVH Potassium channel protein BF17_01120 ENOG4105XXV Acid-resistance protein BF17_01140 ENOG4105E8T Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity) BF17_01170 ENOG4105EFJ Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system (By similarity) BF17_01175 ENOG4108IPX Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity) BF17_01180 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF17_01185 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF17_01190 ENOG4107RNA Nickel ABC transporter, periplasmic nickel-binding protein BF17_01195 ENOG4105VEQ Cold shock protein BF17_01205 ENOG4108SAJ Protein of unknown function (DUF1198) BF17_01210 ENOG4108WMJ Protein of unknown function (DUF2002) BF17_01235 ENOG4107R25 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF17_01240 ENOG4108IJ7 Glycine betaine BF17_01245 ENOG4108HQS Glycine betaine BF17_01250 ENOG4105GIJ Glycine betaine BF17_01260 ENOG4105EW8 cytosine purines, uracil, thiamine, allantoin permease BF17_01270 ENOG4108JDX DNA polymerase iii, epsilon subunit BF17_01280 ENOG4105D1A Methyltransferase BF17_01290 ENOG4105E9H Lytic Murein transglycosylase BF17_01305 ENOG4105CV8 reductase BF17_01340 ENOG4108ZI0 d,d-heptose 1,7-bisphosphate phosphatase BF17_01350 ENOG4108UMI ABC transporter, permease BF17_01355 ENOG4105D01 (LipO)protein BF17_01360 ENOG4108R8X outer membrane lipoprotein BF17_01365 ENOG4108R96 Methyltransferase, YaeB family BF17_01375 ENOG4107EII Lipoprotein involved with copper homeostasis and adhesion BF17_01380 ENOG4108YZN class I peptide chain release factor BF17_01395 ENOG4105M1T rho-binding antiterminator BF17_01405 ENOG4105D3U Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity) BF17_01410 ENOG4108YZK glyoxalase bleomycin resistance protein dioxygenase BF17_01420 ENOG4105C0B DNA polymerase III (alpha subunit) BF17_01430 ENOG4105D0V Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity) BF17_01450 ENOG4108RFI Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity) BF17_01460 ENOG4105DZP Membrane-associated zinc metalloprotease BF17_01465 ENOG4105KNE Phosphatidate cytidylyltransferase BF17_01470 ENOG4105CR3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity) BF17_01500 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BF17_01520 ENOG4105QDK Flavodoxin BF17_01525 ENOG4105DR9 pseudouridine synthase BF17_01530 ENOG4105WP7 tRNA pseudouridine synthase C BF17_01545 ENOG4105EWT decarboxylase family BF17_01565 ENOG4105M08 Membrane BF17_01570 ENOG4105ETT transcriptional Regulator, LysR family BF17_01575 ENOG4105C9B Cysteine desulfurase BF17_01580 ENOG4105P9C Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity) BF17_01585 ENOG4105CUZ uba thif-type nad fad binding protein BF17_01590 ENOG4105CA3 membrane-bound lytic murein transglycosylase BF17_01610 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BF17_01620 ENOG4107QYX exodeoxyribonuclease v alpha BF17_01625 ENOG4107QKA exodeoxyribonuclease V beta BF17_01630 ENOG4107QXK peptidase BF17_01635 ENOG4105DSY exodeoxyribonuclease V, gamma BF17_01670 ENOG4108HRM phosphoenolpyruvate--protein phosphotransferase BF17_01685 ENOG4105CPC Aldo Keto reductase BF17_01715 ENOG41060NJ transcriptional regulator BF17_01720 ENOG4105CU5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity) BF17_01725 ENOG4105RQF LysR family Transcriptional regulator BF17_01730 ENOG4105F27 Major Facilitator BF17_01810 ENOG4105D7Q type ii secretion system BF17_01815 ENOG4107QHF type ii secretion system protein e BF17_01835 ENOG4107B2H carbonic anhydrase BF17_01860 ENOG4105CBG Sulfatase BF17_01870 ENOG4105E98 transcriptional regulator DeoR family BF17_01875 ENOG4105C6Q that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of BF17_01880 ENOG4105E70 isomerase BF17_01885 ENOG4108RG5 PTS system N-acetylgalactosamine-specific transporter subunit IIB BF17_01890 ENOG4105ETZ PTS System BF17_01895 ENOG4105F3R pts system mannose fructose sorbose family iid BF17_01900 ENOG4108YTN IIa component BF17_01905 ENOG4105CE4 GlcNAc 6-P deacetylase BF17_01910 ENOG4105CHR reductase BF17_01920 ENOG4105C4X radical SAM domain protein BF17_01925 ENOG4105ENH Sulfatase BF17_01935 ENOG4105D2N Aldolase BF17_01945 ENOG4105ETE Transcriptional regulator (LacI family BF17_01950 ENOG4105DPW Major facilitator superfamily MFS_1 BF17_01960 ENOG4105ETE Transcriptional regulator (LacI family BF17_01970 ENOG4105CI1 PTS System BF17_01975 ENOG4105C4C beta-galactosidase BF17_01985 ENOG4105EG2 ABC transporter, permease BF17_01995 ENOG4107FKK extracellular solute-binding protein family 1 BF17_02010 ENOG4105CNN ABC, transporter BF17_02015 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BF17_02025 ENOG4108UY0 (LipO)protein BF17_02030 ENOG4105NTW Transcriptional regulator BF17_02105 ENOG4105GMB type VI secretion system effector, hcp1 family BF17_02125 ENOG4105C2R Single-stranded-DNA-specific exonuclease (RecJ) BF17_02130 ENOG4105T95 Thiol disulfide interChange protein BF17_02135 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF17_02140 ENOG41071R3 Low-potential electron donor to a number of redox enzymes (By similarity) BF17_02155 ENOG4105EB3 Histidine kinase BF17_02160 ENOG4105E3W Two component transcriptional regulator (Winged helix family BF17_02170 ENOG4105Y75 tpr repeat protein BF17_02185 ENOG4108UT2 hemolysin iii BF17_02220 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BF17_02225 ENOG4105D0A hydroxylase BF17_02230 ENOG4107RAQ aminopeptidase BF17_02245 ENOG4105MK2 5-formyltetrahydrofolate cyclo-ligase BF17_02250 ENOG4108JQ1 Dehydrogenase BF17_02255 ENOG4105E66 phosphoriboisomerase A BF17_02265 ENOG4105MPN Membrane BF17_02275 ENOG4105D64 Mechanosensitive ion channel BF17_02280 ENOG4105D2N Aldolase BF17_02295 ENOG4105CV1 Transketolase (EC 2.2.1.1) BF17_02300 ENOG4108K0D peptidase, M48 BF17_02310 ENOG4105DP5 Catalyzes the biosynthesis of agmatine from arginine (By similarity) BF17_02325 ENOG4105RWS endonuclease I BF17_02330 ENOG4105QF0 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity) BF17_02335 ENOG4105D7Z glutathione synthase BF17_02350 ENOG4105DCY Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity) BF17_02360 ENOG4105CZX twitching motility protein BF17_02365 ENOG4105DFA alanine racemase domain protein BF17_02370 ENOG4105II7 pyrroline-5-carboxylate reductase BF17_02375 ENOG4108VIA integral membrane protein BF17_02385 ENOG4108V82 Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity) BF17_02390 ENOG4105CSA Coproporphyrinogen iii oxidase BF17_02395 ENOG4105EUK rtx toxin RtxA BF17_02400 ENOG4105K33 Periplasmic Protein BF17_02405 ENOG4105CSV Glutaminase BF17_02410 ENOG41090ED Protein with unknown function (DUF469) BF17_02445 ENOG4105CNN ABC, transporter BF17_02455 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BF17_02460 ENOG4105CXN decarboxylase BF17_02685 ENOG4105VUH addiction module killer protein BF17_02740 ENOG4107QHF type ii secretion system protein e BF17_02820 ENOG4105CDU Replicative dna helicase BF17_02860 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures BF17_03000 ENOG4105VT3 DNA binding domain protein, excisionase family BF17_03170 ENOG4105C7V phospho-2-dehydro-3-deoxyheptonate aldolase BF17_03200 ENOG4107T9Z Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity) BF17_03205 ENOG4105F1A Pyruvate formate-lyase BF17_03210 ENOG4105C6N Formate acetyltransferase BF17_03215 ENOG4105N2W Transcriptional regulator BF17_03345 ENOG4105DUU IucA IucC family protein BF17_03350 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BF17_03360 ENOG4105CT4 transporter BF17_03370 ENOG4105ETE Transcriptional regulator (LacI family BF17_03375 ENOG4105C8P )-transporter BF17_03380 ENOG41062WK cellular response to acidity BF17_03395 ENOG4108WC9 type VI secretion system effector, hcp1 family BF17_03415 ENOG4105CNA YD repeat protein BF17_03435 ENOG41067QW Transcriptional regulator BF17_03465 ENOG4105CNA YD repeat protein BF17_03475 ENOG4105CNA YD repeat protein BF17_03485 ENOG4105CS6 Rhs element vgr protein BF17_03505 ENOG4105C26 Dehydrogenase BF17_03510 ENOG4108Q27 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity) BF17_03515 ENOG4105CHR reductase BF17_03530 ENOG4108I5G Major Facilitator superfamily BF17_03545 ENOG4108FUF Transcriptional regulator, IclR family BF17_03550 ENOG41061TZ Short-chain dehydrogenase reductase Sdr BF17_03570 ENOG4107EFN gluconate transport system permease 3 BF17_03585 ENOG4105BZ1 (ABC) transporter BF17_03615 ENOG4105C0W non-ribosomal peptide synthetase BF17_03635 ENOG4107ZSV Receptor BF17_03640 ENOG4105D42 Cleaves the N-terminal amino acid of tripeptides (By similarity) BF17_03645 ENOG4105CFC Transporter BF17_03655 ENOG4108QHK Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway BF17_03700 ENOG4105C1P efflux transporter, rnd family, mfp subunit BF17_03705 ENOG4105BZU Histidine kinase BF17_03720 ENOG4108XTF Outer Membrane Lipoprotein BF17_03745 ENOG4107RD7 Flagellar Motor Protein, MotA BF17_03775 ENOG4107BRV flagellar capping protein BF17_03780 ENOG4105I03 Flagellin BF17_03785 ENOG4105I03 Flagellin BF17_03795 ENOG4105I03 Flagellin BF17_03800 ENOG4108M3R transcriptional activator CadC BF17_03820 ENOG4105E1Q flagellar hook-associated protein BF17_03830 ENOG4105D92 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity) BF17_03840 ENOG4105CGA flagellar basal-body rod protein FlgG BF17_03845 ENOG4108KPB Flagellar basal-body rod protein FlgF BF17_03850 ENOG4105BZE flagellar hook protein, FlgE BF17_03855 ENOG4105W00 Flagellar hook capping protein BF17_03860 ENOG4108ZC9 flagellar basal-body rod protein flgc BF17_03865 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BF17_03870 ENOG4105XZC flagellar basal body P-ring biosynthesis protein FlgA BF17_03890 ENOG4108JIR Flagellum-specific ATP synthase BF17_03905 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BF17_03915 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BF17_03925 ENOG4105DD5 Flagellar motor switch protein BF17_03930 ENOG4105CN7 Flagellar biosynthetic protein FliP BF17_03935 ENOG4105VS8 Flagellar biosynthetic protein fliq BF17_03940 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BF17_03945 ENOG4105D00 flagellar biosynthetic protein flhB BF17_03965 ENOG4105PEC Iron-enterobactin transporter periplasmic binding protein BF17_03975 ENOG4106P2F Pfam:Pili_assembly_C BF17_03980 ENOG4106PG1 outer membrane usher protein BF17_03990 ENOG4105E03 chitinase BF17_03995 ENOG4108M1A Chitin-binding protein BF17_04020 ENOG4108IJF Heavy metal efflux pump, CzcA BF17_04095 ENOG4108ZZF transport protein (ExbD) BF17_04100 ENOG4105CWK Biopolymer transport protein, ExbB BF17_04105 ENOG4105C28 cystathionine BF17_04110 ENOG4108K81 inner membrane protein YghB BF17_04115 ENOG4105CF7 AraC family transcriptional regulator BF17_04125 ENOG4108I6A alcohol dehydrogenase BF17_04130 ENOG4105CV8 reductase BF17_04145 ENOG4107TZ2 Cell division protein that is required for growth during stress conditions. May be involved in protecting or stabilizing the divisomal assembly under conditions of stress (By similarity) BF17_04155 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF17_04165 ENOG4105NF4 modulator of drug activity BF17_04170 ENOG4105HEI LysR family (Transcriptional regulator BF17_04175 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF17_04180 ENOG4105IPS esterase BF17_04185 ENOG41070EG Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity) BF17_04190 ENOG4108SX3 cytoplasmic protein BF17_04195 ENOG41087AY ADP-Ribose pyrophosphatase BF17_04200 ENOG4105DFG type I secretion outer membrane protein BF17_04215 ENOG4106032 Glutathionylspermidine synthase BF17_04220 ENOG4105C8E extradiol ring-cleavage dioxygenase class IIi protein subunit b BF17_04235 ENOG4105W0Z cytoplasmic protein BF17_04240 ENOG4105DVH amino acid BF17_04255 ENOG4105I7R Adenylate cyclase BF17_04260 ENOG4106MWK domain protein BF17_04275 ENOG4107ZVW dihydroneopterin aldolase BF17_04295 ENOG4105VCC 30S ribosomal protein S21 BF17_04300 ENOG4105C9G DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity) BF17_04305 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF17_04400 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles BF17_04415 ENOG4105MFG Antirestriction protein BF17_04420 ENOG4106H6R UPF0380 protein BF17_04420 ENOG4106H6R UPF0380 protein BF17_04425 ENOG4106J9S Prophage BF17_04440 ENOG4108KZE transcriptional regulator BF17_04445 ENOG4108MXD gtp-binding protein BF17_04475 ENOG4105JXR Protein of unknown function (DUF3296) BF17_04480 ENOG410693A DNA-binding protein BF17_04510 ENOG4105MZU cell filamentation protein BF17_04560 ENOG4105J12 Multidrug resistance protein mdtN BF17_04565 ENOG4108MI0 Resistance protein BF17_04575 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BF17_04585 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BF17_04595 ENOG4108IJG ABC transporter substrate-binding protein BF17_04600 ENOG4107KJX Transcriptional regulator BF17_04605 ENOG4107T40 Inherit from COG: Glycosyltransferase 36 BF17_04610 ENOG4108IJ9 (ABC) transporter BF17_04630 ENOG4105BZ3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity) BF17_04635 ENOG4105DM4 PTS System BF17_04640 ENOG4108YRF PTS System BF17_04645 ENOG4105C6N Formate acetyltransferase BF17_04650 ENOG4108AHH pyruvate formate lyase II activase BF17_04655 ENOG4108XCZ PTS System BF17_04660 ENOG4106R3P AraC family transcriptional regulator BF17_04670 ENOG4105CKT filamentous hemagglutinin BF17_04730 ENOG4105CKT filamentous hemagglutinin BF17_04745 ENOG4105CKT filamentous hemagglutinin BF17_04765 ENOG4105CKT filamentous hemagglutinin BF17_04775 ENOG4105CKT filamentous hemagglutinin BF17_04785 ENOG4105CKT filamentous hemagglutinin BF17_04790 ENOG4105D5K Hemolysin activator protein BF17_04840 ENOG4108M24 von Willebrand factor, type A BF17_04855 ENOG4108M24 von Willebrand factor, type A BF17_04870 ENOG4105CKA Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity) BF17_04875 ENOG4105CE4 GlcNAc 6-P deacetylase BF17_04880 ENOG4105CSH Transporter BF17_04890 ENOG4108YK4 Acid-resistance membrane protein BF17_04895 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BF17_04915 ENOG4108VKG metal-dependent hydrolase BF17_04920 ENOG4105EE0 oxidoreductase BF17_04930 ENOG4105P66 Membrane BF17_04935 ENOG4105CTX dehydratase BF17_04940 ENOG4107QZW Altronate oxidoreductase BF17_04950 ENOG4105DPW Major facilitator superfamily MFS_1 BF17_04970 ENOG4106W5V Membrane BF17_04985 ENOG4105NE1 Conserved Protein BF17_04990 ENOG41090KG Inner membrane protein YqjE BF17_05000 ENOG4108VBZ doxx family BF17_05005 ENOG4105CHF Glutathione S-transferase BF17_05010 ENOG4105CWB LysR family transcriptional Regulator BF17_05020 ENOG4108CNN domain protein BF17_05030 ENOG4105CU0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity) BF17_05050 ENOG4105W4M Transport-associated protein BF17_05065 ENOG4108556 Isoprenoid biosynthesis protein with amidotransferase-like domain BF17_05070 ENOG4105BZU Histidine kinase BF17_05075 ENOG4105N5T Radical SAM Protein BF17_05080 ENOG4105CBC glutamate synthase BF17_05085 ENOG4105BZ8 glutamate synthase BF17_05095 ENOG4105KB2 stringent starvation protein b BF17_05100 ENOG4107MKT Stringent starvation protein a BF17_05120 ENOG4105D6Z AFG1 family ATPase BF17_05125 ENOG4108W2Q Cytochrome d ubiquinol oxidase subunit III BF17_05130 ENOG4105C0H protease BF17_05135 ENOG4105C0H protease BF17_05150 ENOG4105VFK BolA family BF17_05155 ENOG4105UE2 Part of the ABC transporter complex MlaFEDB that actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane BF17_05160 ENOG4105E3I toluene tolerance BF17_05165 ENOG4107PE3 Mammalian cell entry related domain protein BF17_05170 ENOG4105CY3 ABC transporter, permease BF17_05175 ENOG4105DHJ ABC, transporter BF17_05180 ENOG4105FEU K -dependent Na -Ca exchanger BF17_05185 ENOG4105C2X Arabinose 5-phosphate isomerase BF17_05190 ENOG4108Z4R 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase BF17_05195 ENOG4108P1K Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane (By similarity) BF17_05200 ENOG4105WI0 lipopolysaccharide transport periplasmic protein lptA BF17_05205 ENOG4108IUZ ABC transporter BF17_05210 ENOG4105DTW Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF17_05215 ENOG41080QH sigma 54 modulation protein ribosomal protein S30EA BF17_05220 ENOG4107RM2 PTS IIA-like nitrogen-regulatory protein PtsN BF17_05230 ENOG41080Z8 PHOSPHOCARRIER protein BF17_05245 ENOG4105KME endoribonuclease L-psp BF17_05255 ENOG4105D4X repressor BF17_05260 ENOG4105C5Y PTS System BF17_05265 ENOG4105CG3 alpha amylase, catalytic region BF17_05270 ENOG4105NXH GreA GreB family elongation factor BF17_05275 ENOG4108XVM Cytochrome b(562) BF17_05290 ENOG4105CMS peptidase U62, modulator of DNA gyrase BF17_05300 ENOG4105UNR (Barnase) inhibitor BF17_05305 ENOG4105GGE ribonuclease BF17_05310 ENOG4105C26 Dehydrogenase BF17_05335 ENOG4105CR8 Transcriptional regulator BF17_05395 ENOG4105D1U peptidase U62 modulator of DNA gyrase BF17_05405 ENOG4105QD6 exported protein BF17_05410 ENOG4105C03 ribonuclease BF17_05420 ENOG4105VQ7 Rod shape-determining protein MreD BF17_05425 ENOG4105N3I Involved in formation and maintenance of cell shape (By similarity) BF17_05430 ENOG4105DFF Rod shape-determining protein mreb BF17_05435 ENOG41062P1 Diguanylate cyclase phosphodiesterase BF17_05440 ENOG4105D3Z quinone oxidoreductase, yhdh yhfp family BF17_05460 ENOG4105KM4 Acetyl-CoA carboxylase, biotin carboxyl carrier protein BF17_05465 ENOG4105CER acetyl-CoA carboxylase biotin carboxylase BF17_05470 ENOG4105RG0 Membrane BF17_05475 ENOG4108IA2 Sodium pantothenate symporter BF17_05485 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BF17_05490 ENOG4105VY0 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity) BF17_05510 ENOG4108XTF Outer Membrane Lipoprotein BF17_05515 ENOG41076YT nitrate reductase, gamma subunit BF17_05520 ENOG4105R3A Nitrate reductase BF17_05525 ENOG4108IUE nitrate reductase beta subunit BF17_05530 ENOG4105CRU nitrate reductase, alpha subunit BF17_05535 ENOG4105DQQ Major facilitator superfamily MFS_1 BF17_05550 ENOG4105VEQ Cold shock protein BF17_05555 ENOG4105VEQ Cold shock protein BF17_05570 ENOG4105CYM Glutathione S-transferase BF17_05575 ENOG4105C2X Arabinose 5-phosphate isomerase BF17_05580 ENOG4105EF1 ribulokinase BF17_05590 ENOG4105CNN ABC, transporter BF17_05595 ENOG4105C2J ABC transporter BF17_05605 ENOG4105D1S lipid A biosynthesis BF17_05615 ENOG4105EEQ Na H antiporter BF17_05620 ENOG4105C7N Xanthine uracil vitamin C permease BF17_05640 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BF17_05650 ENOG4105GVF (ABC) transporter BF17_05685 ENOG4105CNA YD repeat protein BF17_05725 ENOG4105CNA YD repeat protein BF17_05750 ENOG4105CS6 Rhs element vgr protein BF17_05765 ENOG4105TIV Cryptic phage CTXphi transcriptional repressor RstR BF17_05800 ENOG4105CS6 Rhs element vgr protein BF17_05830 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BF17_05880 ENOG4108WC9 type VI secretion system effector, hcp1 family BF17_05890 ENOG4107W52 maltose operon periplasmic protein BF17_05910 ENOG4107FKK extracellular solute-binding protein family 1 BF17_05915 ENOG4105D56 permease protein BF17_05920 ENOG4105EG2 ABC transporter, permease BF17_05935 ENOG4105CFH Aspartokinase BF17_05940 ENOG4105C09 Bile acid BF17_05955 ENOG4105C3R Methionine synthase BF17_05960 ENOG41069M3 Transcriptional regulator BF17_05975 ENOG4108I9X Isocitrate lyase BF17_05980 ENOG4107QP3 malate synthase g BF17_06040 ENOG4108WI1 Dna topoisomerase BF17_06050 ENOG4105C79 DNA protecting protein DprA BF17_06070 ENOG4105C1A potassium transporter peripheral membrane BF17_06080 ENOG4105VCN Rescues the ribosomes stalled at the 3' end of non-stop mRNAs. May induce hydrolysis of the ribosome-bound peptidyl-tRNA. This activity is crucial when the stalled ribosome can not be rescued by the SsrA(tmRNA)-SmpB quality control system BF17_06085 ENOG4105W1Y Transcriptional regulator BF17_06110 ENOG4108ZT0 50S ribosomal protein l17 BF17_06120 ENOG4105G6W One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity) BF17_06135 ENOG41067V7 50S ribosomal protein L36 BF17_06140 ENOG4105CGG The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity) BF17_06150 ENOG4105VPB 50S ribosomal protein L30 BF17_06155 ENOG4108RA9 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity) BF17_06195 ENOG4105K87 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal BF17_06205 ENOG4108R70 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity) BF17_06210 ENOG4105CKE Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity) BF17_06220 ENOG4105K7S Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity) BF17_06280 ENOG4108UHY One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity) BF17_06305 ENOG4105WWK YheO domain protein BF17_06310 ENOG4108V1T peptidylprolyl cis-trans isomerase BF17_06325 ENOG4108YZY peptidylprolyl cis-trans isomerase BF17_06330 ENOG4105VKU nucleicacid-binding protein BF17_06345 ENOG4105C5H ABC transporter BF17_06350 ENOG4105K64 Glycosyl transferase, family 2 BF17_06360 ENOG4105E2B Taurine dioxygenase BF17_06365 ENOG4105EUS Binding-protein-dependent transport systems, inner membrane component BF17_06375 ENOG4106FTQ Taurine ABC transporter, periplasmic BF17_06385 ENOG4105DNZ Alpha Beta Hydrolase BF17_06395 ENOG4105CJE phosphoribulokinase (EC 2.7.1.19) BF17_06415 ENOG410613R integral membrane protein, YccS YhfK family BF17_06420 ENOG4105C8Y Acetylornithine aminotransferase BF17_06440 ENOG4105D7A ATP-binding protein BF17_06445 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BF17_06455 ENOG4105F8D glycoside hydrolase family 4 BF17_06460 ENOG4105DDV Transcriptional regulator (LacI family BF17_06480 ENOG4105DZC cytosine deaminase BF17_06490 ENOG4105MP0 transposase BF17_06550 ENOG4107QZF nitrite reductase NADPH large subunit BF17_06555 ENOG4105WZK nitrite reductase NADPH small subunit BF17_06560 ENOG4107V9H nitrite transporter BF17_06570 ENOG4105C31 Tryptophanyl-tRNA synthetase BF17_06580 ENOG4105DJV ribulose-phosphate 3-epimerase BF17_06605 ENOG4105E4G Type IV pilus BF17_06630 ENOG4108JQC penicillin-binding protein 1A BF17_06635 ENOG4107RK2 ADP-ribose diphosphatase NudE BF17_06640 ENOG4105DQY intracellular growth attenuator BF17_06645 ENOG4107Y3D HAD-superfamily hydrolase subfamily IA variant 3 BF17_06650 ENOG4105VEJ Heat shock protein BF17_06665 ENOG4105E0F Histidine kinase BF17_06670 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF17_06675 ENOG4108RRZ Transcription elongation factor GreB BF17_06690 ENOG4105XFK Ferrous iron transport protein A BF17_06695 ENOG4105CE1 Ferrous iron transport protein b BF17_06725 ENOG4105MJ2 Competence protein BF17_06735 ENOG4107RTM 4-alpha-glucanotransferase (EC 2.4.1.25) BF17_06740 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BF17_06760 ENOG4105E98 transcriptional regulator DeoR family BF17_06780 ENOG4105C6V Glycerol-3-phosphate dehydrogenase BF17_06785 ENOG4107QQN Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) BF17_06810 ENOG4108HRK Histidine kinase BF17_06835 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BF17_06840 ENOG41076UM multiple antibiotic resistance (MarC)-related protein BF17_06855 ENOG4108Z67 carbohydrate kinase, thermoresistant glucokinase family BF17_06860 ENOG4105C6Z Gluconate BF17_06865 ENOG4105DIQ Transcriptional regulator BF17_06870 ENOG4105C2I pirin domain protein BF17_06875 ENOG4105CBX hi0933 family BF17_06880 ENOG4105CJ3 phosphate transporter BF17_06890 ENOG4108M6U Universal stress protein A BF17_06910 ENOG4105DGW oligopeptidase A BF17_06915 ENOG4105D6S protein involved in catabolism of external DNA BF17_06920 ENOG4105DC8 reductase BF17_06925 ENOG4107VHA regulatoR BF17_06930 ENOG4107QQ0 gntp family BF17_06935 ENOG4105BZW Glycerate kinase BF17_06945 ENOG4105CMM transposase BF17_06975 ENOG4107H3J ribonuclease BF17_06980 ENOG4105EAF CDP-diacylglycerol pyrophosphatase (EC 3.6.1.26) BF17_06985 ENOG41066T0 asmA family BF17_06990 ENOG4105CMB EAL domain-containing protein BF17_06995 ENOG4105VSH 4-oxalocrotonate tautomerase BF17_07000 ENOG4107SS6 2-dehydro-3-deoxygluconokinase BF17_07005 ENOG4105CS0 peptidase BF17_07025 ENOG4108PU9 oligogalacturonate-specific porin BF17_07030 ENOG4105BZU Histidine kinase BF17_07035 ENOG4105K2Z endo-1,4-d-glucanase (EC 3.2.1.4) BF17_07040 ENOG4108JQ7 (ABC) transporter BF17_07045 ENOG4105C3U ABC transporter BF17_07050 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF17_07055 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF17_07060 ENOG4105DEF Extracellular solute-binding protein, family 5 BF17_07080 ENOG4105CKT filamentous hemagglutinin BF17_07090 ENOG4105CXY transporter BF17_07095 ENOG4105BZU Histidine kinase BF17_07100 ENOG4108KX4 response regulator BF17_07105 ENOG4105DIJ Phosphoethanolamine transferase BF17_07125 ENOG4105C85 amino acid BF17_07140 ENOG4105C6T cysteine synthase BF17_07170 ENOG4105CM4 permease protein BF17_07175 ENOG4108IPW abc transporter atp-binding protein BF17_07315 ENOG4105ZTC transcriptional activator, Ogr delta BF17_07345 ENOG4105T16 Transcriptional regulator (AraC family) BF17_07350 ENOG4107RNG ABC transporter BF17_07360 ENOG4105DFW ABC transporter BF17_07370 ENOG4105CMG Carbohydrate kinase BF17_07380 ENOG4108TTM chaperone BF17_07390 ENOG4106EAR Fimbrial protein BF17_07395 ENOG4105MEV Acyl-transferase BF17_07425 ENOG4105EM7 Selenocysteine-specific translation elongation factor BF17_07440 ENOG4108MG3 formate dehydrogenase BF17_07445 ENOG4105QA4 4Fe-4S Ferredoxin, iron-sulfur binding domain protein BF17_07450 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BF17_07455 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BF17_07465 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF17_07470 ENOG4105C8Q Methyl-accepting chemotaxis BF17_07485 ENOG4108YYI Protein of unknown function (DUF2810) BF17_07515 ENOG4105E61 Mannitol repressor protein BF17_07525 ENOG4105CTS PTS system mannitol-specific BF17_07530 ENOG4106JH6 (LipO)protein BF17_07545 ENOG4108R3E Dna-3-methyladenine glycosylase i BF17_07555 ENOG4108ZG0 Ompa motb domain protein BF17_07570 ENOG4107T9C Alpha amylase catalytic region BF17_07585 ENOG4105JKW Valine--pyruvate aminotransferase BF17_07610 ENOG4105R2A (LipO)protein BF17_07615 ENOG4105D99 atp gtp-binding protein BF17_07620 ENOG4105C7B Threonine dehydratase BF17_07635 ENOG410667J hydrolase BF17_07640 ENOG4105C7D DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF17_07655 ENOG4105CZ8 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity) BF17_07670 ENOG4105NVJ RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity) BF17_07680 ENOG4105DHW Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins BF17_07695 ENOG4105C7N Xanthine uracil vitamin C permease BF17_07700 ENOG4107UB3 HAD-superfamily hydrolase subfamily IA variant 3 BF17_07705 ENOG4105DRP amino acid AbC transporter BF17_07710 ENOG4105EAD ABC transporter BF17_07715 ENOG4106PMH Extracellular solute-binding protein family 3 BF17_07735 ENOG4105E2Z phosphate ABC transporter (Permease BF17_07740 ENOG4105C8U phosphate abc transporter BF17_07745 ENOG4107QMV Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity) BF17_07750 ENOG4105C46 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity) BF17_07790 ENOG4105KY6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity) BF17_07800 ENOG4105GXX Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I associates with the membrane and may be involved with cation translocation BF17_07815 ENOG4105QTB Flavodoxin BF17_07820 ENOG4108VVK transcriptional Regulator, AsnC BF17_07845 ENOG4105MRB Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity) BF17_07850 ENOG4105C2J ABC transporter BF17_07855 ENOG4105CNN ABC, transporter BF17_07860 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BF17_07865 ENOG4108RVA ribokinase BF17_07870 ENOG4105ETE Transcriptional regulator (LacI family BF17_07875 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF17_07880 ENOG4107EJG GntR family transcriptional regulator BF17_07920 ENOG4105FNP Molybdopterin-guanine dinucleotide biosynthesis protein b BF17_07930 ENOG4105PC1 Conserved Protein BF17_07935 ENOG4105E27 serine threonine protein kinase BF17_07940 ENOG4108Z33 Thiol disulfide Interchange Protein BF17_07970 ENOG4105D4P Coproporphyrinogen iii oxidase BF17_07975 ENOG4105C1W two component, sigma54 specific, transcriptional regulator, Fis family BF17_07980 ENOG4105CUX Signal transduction histidine kinase BF17_07985 ENOG4105C5F glutamine synthetase BF17_07995 ENOG4105EJU HAD-superfamily hydrolase subfamily IA variant 3 BF17_08010 ENOG4105SUU thioesterase domain BF17_08015 ENOG4105JV1 AsmA family BF17_08020 ENOG4105C2W permease BF17_08025 ENOG4105D6U Sodium Glutamate Symporter BF17_08030 ENOG4105CB5 ATP-dependent DNA helicase recG BF17_08035 ENOG4105FE8 tRNA (Guanosine-2'-O-)-methyltransferase BF17_08040 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BF17_08045 ENOG4105VFG Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity) BF17_08060 ENOG4105EN6 Membrane BF17_08075 ENOG4105CMM transposase BF17_08080 ENOG4105DQ6 Transposase BF17_08085 ENOG4105F5P DNA-damage-inducible protein d BF17_08120 ENOG4105GMB type VI secretion system effector, hcp1 family BF17_08135 ENOG4105DSJ YicC domain protein BF17_08160 ENOG4105CJS Phosphopantothenoylcysteine decarboxylase BF17_08175 ENOG4105W0E 50S ribosomal protein L33 BF17_08195 ENOG4105D8A 3-Deoxy-D-manno-octulosonic-acid transferase BF17_08200 ENOG4105D16 lipopolysaccharide heptosyltransferase i BF17_08205 ENOG4105XA0 heptosyltransferase ii BF17_08215 ENOG4107EEK Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity) BF17_08225 ENOG4105PXI polysaccharide deacetylase BF17_08245 ENOG4107YZP Rhodanese domain protein BF17_08250 ENOG4105VW4 glutaredoxin 3 BF17_08265 ENOG4105D7W serine acetyltransferase BF17_08270 ENOG4108UIQ Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity) BF17_08275 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BF17_08280 ENOG4105E0F Histidine kinase BF17_08285 ENOG4105E3W Two component transcriptional regulator (Winged helix family BF17_08290 ENOG4105FMW periplasmic BF17_08320 ENOG4105DE7 Sulfate ABC transporter periplasmic sulfate-binding protein BF17_08330 ENOG4105EBK exported protein BF17_08335 ENOG4108VTS Membrane BF17_08340 ENOG4105DP0 ferredoxin-NADP reductase BF17_08345 ENOG4105CBT Fructose-1,6-bisphosphatase BF17_08350 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BF17_08355 ENOG4105D8C Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity) BF17_08385 ENOG4105MP0 transposase BF17_08390 ENOG4108JJA ABC, transporter BF17_08395 ENOG4108MBX Secretion Protein BF17_08420 ENOG4105EIS 1,4-dihydroxy-2-naphthoate octaprenyltransferase BF17_08435 ENOG41063M6 Cell Division Protein BF17_08440 ENOG4105ETE Transcriptional regulator (LacI family BF17_08450 ENOG4105C25 Primosomal protein n' BF17_08465 ENOG4108Z12 YiaAB two helix domain-containing protein BF17_08470 ENOG4105GGQ This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis (By similarity) BF17_08475 ENOG4105C28 cystathionine BF17_08480 ENOG4105CFH Aspartokinase BF17_08485 ENOG4105SYT Methylenetetrahydrofolate reductase BF17_08500 ENOG4105C0N N-acetylglutamate semialdehyde dehydrogenase BF17_08520 ENOG4105X58 receptor BF17_08535 ENOG4107QZV Type I secretion membrane fusion protein BF17_08545 ENOG4107QN2 dihydrolipoyl dehydrogenase BF17_08550 ENOG4105EHV domain protein BF17_08555 ENOG4105C5Q Transcriptional regulator BF17_08570 ENOG4108Y73 Membrane BF17_08625 ENOG4107R5U Periplasmic binding protein LacI transcriptional regulator BF17_08630 ENOG4105C2J ABC transporter BF17_08635 ENOG4107R9N ABC transporter BF17_08640 ENOG41062B0 ABC transporter, permease BF17_08650 ENOG4108WFC UPF0438 protein yifE BF17_08655 ENOG4105C0P Mg chelatase subunit ChlI BF17_08670 ENOG4105P3Y Acetolactate synthase 2 regulatory subunit BF17_08675 ENOG4105CM2 brancheD-chain amino acid aminotransferase BF17_08685 ENOG4105C7B Threonine dehydratase BF17_08705 ENOG4105EMY transcriptional regulator BF17_08715 ENOG4108MA7 Inherit from COG: YD repeat protein BF17_08770 ENOG4108VEV chaperone BF17_08780 ENOG4105CW0 outer membrane usher protein BF17_08785 ENOG4105GQR Chaperone BF17_08795 ENOG4105KQ5 peptidylprolyl cis-trans isomerase BF17_08805 ENOG4105C4R Atp-dependent dna helicase BF17_08825 ENOG4105K63 Thioredoxin BF17_08835 ENOG4105ESV Glycosyl transferase, family 4 BF17_08840 ENOG4105SFE lipopolysaccharide biosynthesis protein BF17_08845 ENOG4105EAG UDP-N-acetylglucosamine 2-epimerase BF17_08850 ENOG4108IJ1 Dehydrogenase BF17_08855 ENOG4105C1B dTDP-glucose 4-6-dehydratase BF17_08860 ENOG4108I19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity) BF17_08865 ENOG4108WJ1 acetyltransferase BF17_08870 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BF17_08875 ENOG4105EGZ biosynthesis protein BF17_08895 ENOG4105C85 amino acid BF17_08930 ENOG4105ECF c-methyltransferase BF17_08935 ENOG41076E6 Uroporphyrinogen-III Synthase BF17_08950 ENOG4107T0K Adenylate cyclase BF17_08955 ENOG4107T0K Adenylate cyclase BF17_08980 ENOG4105S7Z (LipO)protein BF17_08990 ENOG4105CT0 Protein of unknown function, DUF484 BF17_08995 ENOG4108IYS Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF17_09000 ENOG4105DFC had-superfamily hydrolase, subfamily ia, variant BF17_09005 ENOG4105C4R Atp-dependent dna helicase BF17_09015 ENOG4105EQN UPF0261 protein BF17_09025 ENOG4107QUT magnesium and cobalt transport protein CorA BF17_09030 ENOG4105FR1 rard protein BF17_09035 ENOG4108VUY thioesterase Superfamily protein BF17_09040 ENOG4105HDD phospholipase BF17_09045 ENOG4105C9U ATP-dependent DNA helicase RecQ BF17_09050 ENOG4105CCF Lysine exporter protein (Lyse ygga) BF17_09055 ENOG410829K Lysine exporter protein (Lyse ygga) BF17_09060 ENOG4108EUD Lysophospholipase BF17_09065 ENOG4105DQF Hydrolase BF17_09075 ENOG4106MZZ glycerophosphoryl diester phosphodiesterase BF17_09080 ENOG4105CXY transporter BF17_09090 ENOG4107R5Y anaerobic glycerol-3-phosphate dehydrogenase, subunit A BF17_09100 ENOG4105CHG glycolate oxidase (iron-sulfur subunit) BF17_09105 ENOG4108W1V Lipoprotein BF17_09110 ENOG4105EX9 Membrane BF17_09130 ENOG4107FS9 Membrane BF17_09145 ENOG4105MG3 Membrane BF17_09150 ENOG4106H78 methyltransferase BF17_09155 ENOG4105CCP Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) BF17_09160 ENOG4105CAK Cell division ATP-binding protein ftsE BF17_09165 ENOG4105CRP Part of the ABC transporter FtsEX involved in BF17_09175 ENOG4105U59 -acetyltransferase BF17_09180 ENOG4105CP9 extracellular ligand-binding receptor BF17_09185 ENOG4105C32 Amino acid ABC transporter (Permease) BF17_09190 ENOG4105CF8 branched-chain amino acid ABC transporter, permease BF17_09195 ENOG4105C0Z ABC transporter BF17_09200 ENOG4108IV0 ABC, transporter BF17_09260 ENOG4107T6V glycerophosphoryl diester phosphodiesterase BF17_09280 ENOG4105EMK carboxylate amino acid amine transporter BF17_09285 ENOG4105DZ2 Transcriptional regulator BF17_09295 ENOG4105CDZ Carboxymethylenebutenolidase (EC 3.1.1.45) BF17_09300 ENOG4108I5U Uridine phosphorylase BF17_09315 ENOG4108KF1 Membrane BF17_09320 ENOG4105CGY Dna recombination protein BF17_09330 ENOG4105JC1 sterol-binding domain protein BF17_09340 ENOG4105WKS Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity) BF17_09350 ENOG4105DCX Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity) BF17_09360 ENOG4105D52 delta-aminolevulinic acid dehydratase BF17_09365 ENOG4105MDZ Transcriptional activator rfaH BF17_09375 ENOG4107QK7 reductase BF17_09395 ENOG4108ZK7 protein family UPF0029, Impact, N-terminal protein BF17_09400 ENOG4105D37 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity) BF17_09405 ENOG4108RR8 protoporphyrinogen oxidase BF17_09440 ENOG4105HJX Biotin- acetyl-CoA-carboxylase ligase BF17_09475 ENOG4105PM1 preprotein translocase subunit SecE BF17_09480 ENOG4105E5V Participates in transcription elongation, termination and antitermination (By similarity) BF17_09520 ENOG4105D41 biosynthesis protein thiH BF17_09530 ENOG4105WHD thiamine biosynthesis protein ThiS BF17_09535 ENOG4105D06 uba thif-type nad fad binding protein BF17_09545 ENOG4105CBF Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity) BF17_09565 ENOG4105Y7X Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity) BF17_09570 ENOG4105R2J Conserved Protein BF17_09580 ENOG4108T8B Protein of unknown function (DUF1481) BF17_09585 ENOG4105C12 Phosphoribosylglycinamide synthetase BF17_09650 ENOG41062QD Membrane BF17_09660 ENOG4105CK2 sodium dicarboxylate symporter BF17_09665 ENOG4105WH1 Two component transcriptional regulator luxr family BF17_09735 ENOG4108JIR Flagellum-specific ATP synthase BF17_09750 ENOG41063Q7 Type III secretion system protein BF17_09760 ENOG41083GP type iii secretion BF17_09765 ENOG4108TN6 type iii secretion BF17_09770 ENOG4108IUF type iii secretion BF17_09780 ENOG41066VF YeeE YedE family protein BF17_09785 ENOG4105KSU Redox protein BF17_09800 ENOG4105EHG Permease protein BF17_09805 ENOG4107R4I Periplasmic binding protein BF17_09810 ENOG4106QJH hemin transport protein BF17_09815 ENOG4107ENK receptor BF17_09820 ENOG4107F3C Hemin uptake protein BF17_09830 ENOG41090JE Utilization Protein BF17_09835 ENOG4105D4P Coproporphyrinogen iii oxidase BF17_09855 ENOG4105DAX Pfam:DUF2983 BF17_09915 ENOG4108S1B Periplasmic chaperone protein BF17_09950 ENOG41080IJ Diacylglycerol kinase BF17_09960 ENOG4105MYN Zinc uptake regulation protein BF17_09965 ENOG4105CEH Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity) BF17_09970 ENOG4105P4Z Phage shock protein G BF17_09975 ENOG4105EE6 Alcohol dehydrogenase zinc-binding domain protein BF17_09980 ENOG4105CDU Replicative dna helicase BF17_09985 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BF17_09990 ENOG4105CGF Aromatic amino acid aminotransferase BF17_09995 ENOG4105MSB protein, conserved in bacteria BF17_10000 ENOG4105C5U The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity) BF17_10005 ENOG4108UUM single-stranded DNA-binding protein BF17_10045 ENOG4105CMM transposase BF17_10055 ENOG4105C0A alcohol dehydrogenase BF17_10145 ENOG4108T1M outer membrane protein x BF17_10170 ENOG4108SIC Transcriptional regulator BF17_10175 ENOG4105BZ8 glutamate synthase BF17_10180 ENOG4108RC0 Electron transport protein BF17_10185 ENOG4107QIW Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity) BF17_10225 ENOG4108ZVF (LipO)protein BF17_10230 ENOG4105CK3 Lysine 2,3-aminomutase YodO family protein BF17_10240 ENOG4105KPY Small multidrug resistance protein BF17_10250 ENOG4108VP9 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane (By similarity) BF17_10275 ENOG4105EGS Mechanosensitive ion channel BF17_10290 ENOG4108RBP 3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity) BF17_10310 ENOG4105EH2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity) BF17_10315 ENOG4105DR1 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) BF17_10320 ENOG4105K8N protein family UPF0079, ATPase BF17_10325 ENOG4105C5C n-acetylmuramoyl-l-alanine amidase BF17_10340 ENOG4105KW8 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity) BF17_10345 ENOG4105C1N GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity) BF17_10350 ENOG4107QJR hflk protein BF17_10355 ENOG4105EPW hflc protein BF17_10375 ENOG4105C40 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity) BF17_10380 ENOG4105C2N RNA methyltransferase TrmH family group 3 BF17_10385 ENOG4105CSU acyl-Coa dehydrogenase BF17_10390 ENOG4105WSB biofilm stress and motility protein A BF17_10395 ENOG4108MXZ Esterase BF17_10400 ENOG4108ZDX Binds together with S18 to 16S ribosomal RNA (By similarity) BF17_10410 ENOG4105VH8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity) BF17_10425 ENOG4105FHY Opacity-associated protein A BF17_10435 ENOG4108V1T peptidylprolyl cis-trans isomerase BF17_10455 ENOG4108RNI 3'(2')5'-bisphosphate nucleotidase BF17_10460 ENOG4108UUE Transcriptional regulator BF17_10465 ENOG41061GZ Protein of unknown function (DUF1107) BF17_10470 ENOG4105C37 (CBS) domain BF17_10480 ENOG4105CFU surface antigen BF17_10485 ENOG4105MA0 exported protein BF17_10490 ENOG4108ZHD aig2 family BF17_10495 ENOG4105F0N pyrophosphate phospho-hydrolase BF17_10505 ENOG4105DFU Cell wall formation (By similarity) BF17_10520 ENOG4105HVQ Regulatory factor of maltose metabolism BF17_10530 ENOG4105EAH synthase BF17_10545 ENOG4105QYV Membrane BF17_10570 ENOG4105GMB type VI secretion system effector, hcp1 family BF17_10600 ENOG4106HRJ d-alanyl-d-alanine carboxypeptidase BF17_10605 ENOG4108UKH Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity) BF17_10610 ENOG4105HBR Rna-binding protein BF17_10620 ENOG4105C3H Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity) BF17_10625 ENOG4105EEI dihydropteroate synthase BF17_10655 ENOG4105CHV Transcription elongation factor NusA BF17_10690 ENOG4105C1J atp-dependent rna helicase BF17_10695 ENOG4105DEN Luciferase family BF17_10700 ENOG4106RZ4 Peptidase U32 BF17_10705 ENOG4105CFP Peptidase U32 BF17_10710 ENOG4105XPQ lipid carrier protein BF17_10715 ENOG4108YYD acetyltransferase BF17_10720 ENOG41082IR Excinuclease ABC C subunit domain protein BF17_10740 ENOG4105EQ7 Binding-protein-dependent transport systems, inner membrane component BF17_10745 ENOG4105DRS transport system, permease BF17_10770 ENOG4105K4T epimerase BF17_10775 ENOG4107SA6 carbon-phosphorus lyase complex accessory protein BF17_10780 ENOG4105MFQ Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) (By similarity) BF17_10785 ENOG4105FD8 phosphonate metabolism protein PhnM BF17_10790 ENOG4105HRV phosphonate c-p lyase system protein phnl BF17_10795 ENOG4105ENV phosphonate C-P lyase system protein PhnK BF17_10800 ENOG4105FT8 Phosphonate metabolism BF17_10805 ENOG4105EKV Phosphonate metabolism protein BF17_10810 ENOG4105KZ6 phosphonate C-P lyase system protein PhnH BF17_10815 ENOG4105KQZ Phosphonate C-P lyase system protein PhnG BF17_10820 ENOG4107RJJ Transcriptional regulator BF17_10825 ENOG4108RDD Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity) BF17_10830 ENOG4105CJD (Anaerobic) ribonucleoside-triphosphate reductase BF17_10835 ENOG4108JQ7 (ABC) transporter BF17_10840 ENOG4105C3U ABC transporter BF17_10845 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF17_10850 ENOG4105CJM Binding-protein-dependent transport systems, inner membrane component BF17_10860 ENOG4105XEP YhcH YjgK YiaL family protein BF17_10875 ENOG4105KQT Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity) BF17_10880 ENOG4108MJ3 acetyltransferase BF17_10890 ENOG4105MYG DNA polymerase iii, chi subunit BF17_10900 ENOG4108M8S permease YjgP YjgQ family protein BF17_10905 ENOG4108K5H permease YjgP YjgQ family protein BF17_10920 ENOG4105GMB type VI secretion system effector, hcp1 family BF17_10965 ENOG4108M3P Membrane BF17_10975 ENOG4105RI1 glycoprotein receptor BF17_11000 ENOG4105DHQ Histidine kinase BF17_11040 ENOG4105DKT Transcriptional regulator BF17_11050 ENOG4105DKP glycosyl transferase, family 9 BF17_11065 ENOG410624X efflux transporter, rnd family, mfp subunit BF17_11070 ENOG4105BZS acriflavin resistance protein BF17_11085 ENOG4105VDH Dihydroxyacetone kinase BF17_11110 ENOG4105BZU Histidine kinase BF17_11140 ENOG4108WPU DNA polymerase III subunit psi BF17_11145 ENOG4105KEG ribosomal-protein-alanine acetyltransferase BF17_11155 ENOG4105K3G Periplasmic Protein BF17_11165 ENOG4108NRW Phospholipase, patatin family BF17_11170 ENOG4105EYA deoxyribonuclease BF17_11175 ENOG4105D9N nucleoside BF17_11180 ENOG4105FCI Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity) BF17_11200 ENOG41062Z9 Membrane BF17_11205 ENOG4105EAC phosphoserine phosphatase BF17_11210 ENOG4105DNJ May play a role in the repair of endogenous alkylation damage (By similarity) BF17_11215 ENOG4107VZS Nicotinamide-nucleotide adenylyltransferase BF17_11230 ENOG4105C5H ABC transporter BF17_11235 ENOG41090EK ompa motb domain protein BF17_11240 ENOG4108KHX Diguanylate cyclase BF17_11255 ENOG4107SC1 transglycosylase BF17_11260 ENOG4105R9M This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region (By similarity) BF17_11275 ENOG4105UEI Transcriptional Regulator AraC Family BF17_11280 ENOG4108RH0 Crea protein BF17_11285 ENOG41065U4 response regulator BF17_11315 ENOG4108RIR Molybdenum cofactor biosynthesis protein BF17_11325 ENOG4107F1U Beta/Gamma crystallin BF17_11330 ENOG4106HK8 GPR1 FUN34 yaaH family protein BF17_11350 ENOG41063Z6 transcriptional regulator, lysR family BF17_11360 ENOG4105DTN riboflavin biosynthesis protein ribF BF17_11375 ENOG41090X3 Peptidyl-prolyl cis-trans isomerase BF17_11390 ENOG4105C1M carbamoyl-phosphate synthetase glutamine chain BF17_11395 ENOG4105CU6 carbamoyl-phosphate synthetase ammonia chain BF17_11400 ENOG4105N14 lysine exporter protein LysE YggA BF17_11405 ENOG4105DWK Membrane BF17_11415 ENOG4108YYV Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity) BF17_11455 ENOG4105DBD Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity) BF17_11470 ENOG4105D3G Pseudouridine synthase BF17_11515 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BF17_11520 ENOG4105CS6 Rhs element vgr protein BF17_11580 ENOG4105CQ2 DNA polymerase BF17_11585 ENOG4108KF1 Membrane BF17_11595 ENOG4106SMU thiamine transporter membrane protein BF17_11600 ENOG4105DP9 ABC transporter BF17_11625 ENOG4105S8Q sugar efflux transporter BF17_11640 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BF17_11650 ENOG41064T2 transcriptional regulator, lysR family BF17_11660 ENOG4108IQE Amp-dependent synthetase and ligase BF17_11665 ENOG4105C7K acetolactate synthase BF17_11670 ENOG4108ZP8 Acetolactate synthase small subunit BF17_11675 ENOG4107B7Y DNA-binding transcriptional regulator FruR BF17_11680 ENOG4108RNS Exports L-alanine (By similarity) BF17_11695 ENOG41063Y6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity) BF17_11700 ENOG4105CJN penicillin-binding protein BF17_11705 ENOG4107EEN Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity) BF17_11710 ENOG4108EQQ Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity) BF17_11725 ENOG4105CNI cell division protein FtsW BF17_11745 ENOG4105K7E Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity) BF17_11750 ENOG4105CIT This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity) BF17_11755 ENOG4105CDK Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity) BF17_11780 ENOG4105M6F mutator MutT protein BF17_11795 ENOG4108ZQD Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity) BF17_11805 ENOG4105D7Q type ii secretion system BF17_11810 ENOG4107QHF type ii secretion system protein e BF17_11815 ENOG4108ZUW Major pilin subunit BF17_11820 ENOG4105D18 nicotinate-nucleotide pyrophosphorylase BF17_11825 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BF17_11830 ENOG4106A72 regulatory protein AmpE BF17_11835 ENOG4105C85 amino acid BF17_11840 ENOG41073TP transcriptional regulator BF17_11845 ENOG4105DAQ Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity) BF17_11850 ENOG4107QSN dihydrolipoamide acetyltransferase BF17_11855 ENOG4107QN2 dihydrolipoyl dehydrogenase BF17_11860 ENOG4107QIJ Aconitate hydratase 2 BF17_11870 ENOG4105RPH Inner membrane protein YddG BF17_11890 ENOG4108ZRK uncharacterized protein yacC BF17_11895 ENOG4105E3B Multicopper oxidase BF17_11905 ENOG4108UGV hypoxanthine phosphoribosyltransferase BF17_11910 ENOG41077A9 carbonic anhydrase BF17_11915 ENOG4105DA5 (ABC) transporter BF17_11920 ENOG4105E3A (ABC) transporter BF17_11925 ENOG4107BJW polysaccharide deacetylase BF17_11950 ENOG4105K8U 2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase BF17_11955 ENOG4105DJ0 Poly(A) Polymerase BF17_11960 ENOG4106F3G Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity) BF17_11965 ENOG4108V7X Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters BF17_11975 ENOG4107XID 2'-5' rna ligase BF17_11980 ENOG4105CQ7 ATP-dependent helicase BF17_11985 ENOG4105BZ4 penicillin-binding protein BF17_11990 ENOG4105E0A ABC, transporter BF17_11995 ENOG4105J76 Periplasmic binding protein BF17_12000 ENOG4105S6R Iron-hydroxamate transporter permease subunit BF17_12020 ENOG4105EN6 Membrane BF17_12040 ENOG4105C0H protease BF17_12060 ENOG4105BZT Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity) BF17_12065 ENOG4105CWR In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity) BF17_12070 ENOG4105DXN mazG family BF17_12090 ENOG4105EIZ Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity) BF17_12095 ENOG4107ZIF 6-carboxy-5,6,7,8-tetrahydropterin synthase BF17_12140 ENOG4108I67 Catalyzes the synthesis of activated sulfate (By similarity) BF17_12145 ENOG4105N0Z inner membrane protein ygbE BF17_12180 ENOG4108K5P (LipO)protein BF17_12185 ENOG4105DG1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF17_12190 ENOG4105D86 that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity) BF17_12225 ENOG4105CMM transposase BF17_12240 ENOG4108YZG isomerase BF17_12245 ENOG4105CPQ Dehydrogenase BF17_12250 ENOG4105CHR reductase BF17_12255 ENOG4105CMT Dihydroxyacetone kinase BF17_12265 ENOG4105DKT Transcriptional regulator BF17_12295 ENOG4105E89 ABC transporter BF17_12300 ENOG4105CA0 peroxidase BF17_12310 ENOG4105D05 Receptor BF17_12320 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BF17_12330 ENOG4107GFK fumarate BF17_12335 ENOG4105CMG Carbohydrate kinase BF17_12340 ENOG41064BZ L-xylulose 5-phosphate 3-epimerase BF17_12350 ENOG4105CNN ABC, transporter BF17_12355 ENOG4105C2J ABC transporter BF17_12365 ENOG4105E98 transcriptional regulator DeoR family BF17_12370 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BF17_12375 ENOG4107QY8 reductase BF17_12380 ENOG4105QAX Iron-sulfur BF17_12385 ENOG4107KGK dmso reductase anchor subunit BF17_12390 ENOG4108NEM leader-binding protein dmsD BF17_12395 ENOG4105CPW cytochrome b561 BF17_12400 ENOG4108XVM Cytochrome b(562) BF17_12420 ENOG4105C2J ABC transporter BF17_12425 ENOG4105CNN ABC, transporter BF17_12430 ENOG4108HHA Transketolase BF17_12435 ENOG4108IUS Transketolase BF17_12440 ENOG4107QVN Key enzyme in the regulation of glycerol uptake and metabolism (By similarity) BF17_12455 ENOG4108ISG Major Facilitator BF17_12485 ENOG4105VM8 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity) BF17_12510 ENOG4107VXZ Hydrolase BF17_12515 ENOG4105W39 Membrane BF17_12530 ENOG4108JU6 CBS domain protein BF17_12535 ENOG4106KVJ cytochrome C assembly protein BF17_12540 ENOG4105CB9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY BF17_12565 ENOG4108NE3 Salt-induced outer membrane protein BF17_12570 ENOG4105DS2 Anaerobic c4-dicarboxylate transporter BF17_12575 ENOG4108NEV two component transcriptional regulator, LytTR family BF17_12580 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BF17_12595 ENOG4108WPH sigma 54 modulation protein ribosomal protein S30EA BF17_12600 ENOG4106SNF Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane BF17_12605 ENOG4105C34 Pseudouridine synthase BF17_12610 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BF17_12615 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BF17_12655 ENOG4105T42 (LipO)protein BF17_12660 ENOG4105JIM Phosphatidylserine synthase BF17_12665 ENOG4105CD5 CoA-binding domain protein BF17_12670 ENOG4106IUH DTW domain containing protein BF17_12675 ENOG4105K63 Thioredoxin BF17_12680 ENOG4105EIB trna rrna methyltransferase BF17_12685 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF17_12690 ENOG4105CW7 secretion protein, HlyD family BF17_12695 ENOG4105NTK Transcriptional repressor Mpra BF17_12700 ENOG4105ZED uncharacterized protein ygaH BF17_12705 ENOG4108UMN azlc family BF17_12725 ENOG4105F87 Dehydratase BF17_12730 ENOG4105DRP amino acid AbC transporter BF17_12735 ENOG4105E5Q amino acid AbC transporter BF17_12745 ENOG4105C5R Aminotransferase BF17_12760 ENOG4105CHM Aminotransferase BF17_12800 ENOG4106YJS accessory processing protein BF17_12810 ENOG4107QPN acyl-Coa dehydrogenase BF17_12820 ENOG4105E7A Glutamine amidotransferase BF17_12825 ENOG4105F7V ErfK ybiS ycfS ynhG family protein BF17_12830 ENOG4105DWQ NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BF17_12835 ENOG4108J5C NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BF17_12840 ENOG4106I92 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BF17_12850 ENOG4108IUB NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BF17_12860 ENOG4105CJ2 (LipO)protein BF17_12880 ENOG4105CIN aminoacyl-histidine dipeptidase BF17_12945 ENOG4105F2W methyltransferase BF17_12975 ENOG4105DKQ ROK family BF17_12980 ENOG4105EYH Exonuclease BF17_12985 ENOG4107RH8 nuclease SbcCD subunit D BF17_12990 ENOG4105CK6 Two component transcriptional regulator (Winged helix family BF17_12995 ENOG4105BZU Histidine kinase BF17_13005 ENOG4105CWM branched-chain amino acid transport system II carrier protein BF17_13010 ENOG4105C85 amino acid BF17_13015 ENOG4107R28 alpha amylase, catalytic region BF17_13020 ENOG4105CHR reductase BF17_13030 ENOG4105D3R alkyl hydroperoxide reductase BF17_13035 ENOG4108ZYK Acyl carrier protein phosphodiesterase BF17_13040 ENOG4105E2N Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity) BF17_13050 ENOG4105VIE preprotein translocase, subunit YajC BF17_13055 ENOG4107QN8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BF17_13060 ENOG4107RAB Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity) BF17_13080 ENOG4105D1W Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity) BF17_13095 ENOG4105CG2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity) BF17_13100 ENOG4108ZAI phosphatidylglycerophosphatase a BF17_13110 ENOG4105CTB Polyprenyl synthetase BF17_13125 ENOG4107S0N DJ-1 family BF17_13130 ENOG4108JZF Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity) BF17_13140 ENOG4107RDB Major Facilitator BF17_13150 ENOG41090KH cytochrome o ubiquinol oxidase (subunit iv) BF17_13155 ENOG4105CCU oxidase (Subunit III) BF17_13160 ENOG4105BZ9 Cytochrome C oxidase, subunit I BF17_13165 ENOG4105E2S oxidase) subunit II BF17_13170 ENOG4108NFH Sugar hydrolase BF17_13180 ENOG4105EYM Major Facilitator superfamily BF17_13185 ENOG4105IEY (LipO)protein BF17_13190 ENOG4105M85 Bola protein BF17_13210 ENOG4105C6P ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity) BF17_13215 ENOG4105K70 DNA-binding protein BF17_13220 ENOG4105EIN peptidylprolyl cis-trans isomerase BF17_13230 ENOG4108TGP Thioesterase superfamily protein BF17_13240 ENOG4108NFA extracellular solute-binding protein BF17_13255 ENOG4108XM1 transcriptional regulator AsnC family BF17_13260 ENOG4105BZ1 (ABC) transporter BF17_13265 ENOG4105BZ1 (ABC) transporter BF17_13270 ENOG4108YZA Nitrogen regulatory protein pii BF17_13275 ENOG4105BZU Histidine kinase BF17_13280 ENOG4105C29 acyl-CoA thioesterase BF17_13285 ENOG4108MNP Glycoprotein polysaccharide metabolism BF17_13290 ENOG41080UX Methyltransferase BF17_13300 ENOG4105KF5 hemolysin expression-modulating protein BF17_13305 ENOG4108UKR Biofilm formation regulator YbaJ BF17_13320 ENOG4105BZS acriflavin resistance protein BF17_13325 ENOG4105C1P efflux transporter, rnd family, mfp subunit BF17_13330 ENOG4108IG5 Transcriptional regulator BF17_13335 ENOG41090EX DsrE family BF17_13340 ENOG4105EGS Mechanosensitive ion channel BF17_13355 ENOG4105WD1 Membrane BF17_13365 ENOG4107QMP dna polymerase iii subunits gamma and tau BF17_13375 ENOG4105F3K May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity) BF17_13395 ENOG4108EX3 reductase BF17_13400 ENOG4105EJZ Glucose-1-phosphate cytidylyltransferase BF17_13405 ENOG4105FAW cDP-glucose 4,6-dehydratase BF17_13410 ENOG4105CF4 DegT DnrJ EryC1 StrS aminotransferase BF17_13415 ENOG4105C7K acetolactate synthase BF17_13435 ENOG4105C0K Gdp-mannose 4,6-dehydratase BF17_13450 ENOG4105CJT Mannose-1-phosphate guanylyltransferase BF17_13485 ENOG4105K64 Glycosyl transferase, family 2 BF17_13490 ENOG4108QY5 Ferric enterobactin transport protein BF17_13495 ENOG4105DMT epimerase dehydratase BF17_13505 ENOG4105CMR udp-glucose 4-epimerase BF17_13510 ENOG4107RE1 Inosine-guanosine kinase BF17_13525 ENOG4105EU0 Major facilitator Superfamily BF17_13530 ENOG4105CGH 5'-nucleotidase BF17_13540 ENOG4108Z66 YbaK ebsC protein BF17_13545 ENOG4105MBR gumn family BF17_13550 ENOG4105C59 p-type ATPase BF17_13555 ENOG4108Z6Z Transcriptional regulator BF17_13560 ENOG4105G5H Membrane BF17_13565 ENOG4107QX8 SPFH domain, Band 7 family protein BF17_13570 ENOG4107QR8 Thioredoxin BF17_13575 ENOG4105E1F short-chain dehydrogenase reductase BF17_13580 ENOG4108UJV acyl-CoA thioesterase i BF17_13585 ENOG4108I0Y (ABC) transporter BF17_13590 ENOG4105CV6 ABC transporter, permease BF17_13595 ENOG4105CY8 phosphoribosylaminoimidazole carboxylase atpase subunit BF17_13600 ENOG4108UM6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity) BF17_13610 ENOG4108R5K PPIases accelerate the folding of proteins (By similarity) BF17_13620 ENOG4105WQ3 Rna-binding protein BF17_13670 ENOG4105C3X it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity) BF17_13675 ENOG4105C4R Atp-dependent dna helicase BF17_13680 ENOG4105T40 surface antigen msp4 family protein BF17_13705 ENOG4108MXD gtp-binding protein BF17_13710 ENOG4108KZE transcriptional regulator BF17_13730 ENOG4106H6R UPF0380 protein BF17_13735 ENOG4105MFG Antirestriction protein BF17_13740 ENOG4105W5Q DNA repair protein (RadC BF17_13750 ENOG4108X3P Toxic component of a toxin-antitoxin (TA) module. Overexpression results in inhibition of growth in liquid cultures BF17_13755 ENOG4105MAW Antitoxin component of a toxin-antitoxin (TA) module. Labile antitoxin that counteracts the effect of the CbtA (YeeV) toxin. It does not bind to the cognate toxin but instead binds to MreB and FtsZ (the toxin targets), enhancing their polymerization by forming higher-order bundles BF17_13765 ENOG4108KU3 Integrase BF17_13800 ENOG4107QK4 glycoside hydrolase, family 3 domain protein BF17_13815 ENOG4105FE9 pseudouridine synthase BF17_13820 ENOG4105EZE Cupin 4 family protein BF17_13855 ENOG4108WC9 type VI secretion system effector, hcp1 family BF17_13870 ENOG4105HVQ Regulatory factor of maltose metabolism BF17_13875 ENOG4108JQB penicillin-binding protein 1C BF17_13880 ENOG4105DN3 alpha-2-macroglobulin domain protein BF17_13890 ENOG4105C26 Dehydrogenase BF17_13895 ENOG4108HRG Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity) BF17_13905 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BF17_13910 ENOG4105C2J ABC transporter BF17_13915 ENOG4105CNN ABC, transporter BF17_13920 ENOG4105CK5 oxidoreductase BF17_13925 ENOG4105EDK PfkB domain protein BF17_13935 ENOG4105DH8 myo-inositol catabolism BF17_13945 ENOG4108JJ7 ABC transporter BF17_13965 ENOG4105C5A transporter BF17_13975 ENOG4108N8T regulatoR BF17_13990 ENOG4105VEQ Cold shock protein BF17_13995 ENOG4107Z6W Protein CrcB homolog BF17_14000 ENOG410607N Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatE shares overlapping functions with TatA (By similarity) BF17_14020 ENOG4105DZ1 carboxypeptidase BF17_14025 ENOG4105K6T rare lipoprotein A BF17_14030 ENOG4105CNI cell division protein FtsW BF17_14035 ENOG4105CJN penicillin-binding protein BF17_14045 ENOG4105KEM Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity) BF17_14055 ENOG4105DJF DNA polymerase III, delta' subunit BF17_14070 ENOG4107PAI alpha helical protein BF17_14075 ENOG4105CDA abc transporter atp-binding protein BF17_14080 ENOG4105DRP amino acid AbC transporter BF17_14085 ENOG4105EAD ABC transporter BF17_14090 ENOG4107RP9 extracellular solute-binding protein, family 3 BF17_14095 ENOG4105CE8 Transfers the fatty acyl group on membrane lipoproteins (By similarity) BF17_14100 ENOG4108JU5 Magnesium and cobalt efflux protein BF17_14110 ENOG4105C9A Phoh family BF17_14120 ENOG4105EAK ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family BF17_14155 ENOG4105CAQ asparagine synthetase BF17_14160 ENOG4105D4U had-superfamily hydrolase, subfamily iia BF17_14165 ENOG4105E2R ROK family BF17_14170 ENOG4105CE4 GlcNAc 6-P deacetylase BF17_14180 ENOG4105CI1 PTS System BF17_14205 ENOG41090R7 Ferric uptake BF17_14210 ENOG4105MHQ Low-potential electron donor to a number of redox enzymes (By similarity) BF17_14215 ENOG4105NNH LexA regulated protein BF17_14240 ENOG4107R08 Integrase BF17_14265 ENOG4108R7K Metal Dependent Phosphohydrolase BF17_14270 ENOG4108HJ1 Uncharacterized conserved protein (DUF2303) BF17_14275 ENOG4105H40 BF17_14305 ENOG4108S1U BF17_14315 ENOG4105YQ0 BF17_14340 ENOG4108ZUE Phage regulatory protein rha BF17_14345 ENOG4108MXB Protein of unknown function (DUF968) BF17_14350 ENOG4105HRS Antitermination protein BF17_14515 ENOG4108X9F tail fiber protein BF17_14520 ENOG4105UZW Tail fiber assembly protein BF17_14530 ENOG4108Z1B Cyclase dehydrase BF17_14540 ENOG4105YRI Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BF17_14545 ENOG4105C4F May be involved in recombinational repair of damaged DNA (By similarity) BF17_14550 ENOG4105F91 Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity) BF17_14560 ENOG4105BZN citrate synthase BF17_14565 ENOG4108UTY succinate dehydrogenase, cytochrome b556 subunit BF17_14570 ENOG4105N1I succinate dehydrogenase, hydrophobic membrane anchor protein BF17_14580 ENOG4105E33 succinate dehydrogenase BF17_14585 ENOG4105C7P 2-oxoglutarate dehydrogenase, E1 BF17_14590 ENOG4105C7S Dehydrogenase BF17_14600 ENOG4105CH8 Succinyl-CoA ligase ADP-forming subunit alpha BF17_14605 ENOG4105C4M (Ubiquinol oxidase) subunit I BF17_14610 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BF17_14620 ENOG4105KJB cyd operon protein YbgE BF17_14625 ENOG4107YD3 Thioesterase BF17_14630 ENOG4105E02 MotA TolQ exbB proton channel BF17_14635 ENOG4105M8F Biopolymer transport protein exbD tolR BF17_14640 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BF17_14640 ENOG4108Z82 Cell envelope integrity inner membrane protein TolA BF17_14650 ENOG4105KCK Peptidoglycan-associated lipoprotein BF17_14655 ENOG4105UFD tol-pal system protein YbgF BF17_14705 ENOG4106Z1T Nicotinamide Mononucleotide Transporter BF17_14710 ENOG4105PGM cation diffusion facilitator family transporter BF17_14715 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BF17_14730 ENOG4105ENN converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) BF17_14740 ENOG4105F0Z galactose-1-phosphate uridylyltransferase BF17_14745 ENOG4105CMR udp-glucose 4-epimerase BF17_14760 ENOG4105DKW ABC transporter BF17_14765 ENOG4105F4R Transcriptional regulator mode BF17_14770 ENOG410680R Protein of unknown function (DUF2592) BF17_14775 ENOG4108S6J ABC transporter, periplasmic molybdate-binding protein BF17_14780 ENOG4105E0C molybdate abc transporter BF17_14790 ENOG4108K4B hydrolase BF17_14815 ENOG410626R Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity) BF17_14820 ENOG4105E78 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BF17_14840 ENOG4105VYA Uncharacterized conserved protein (DUF2132) BF17_14845 ENOG4105CHW UPF0052 protein BF17_14850 ENOG4105CM1 Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity) BF17_14860 ENOG4105M00 molybdopterin converting factor, subunit 1 BF17_14865 ENOG4108ZAF Molybdopterin BF17_14870 ENOG4105HFZ Membrane BF17_14890 ENOG4105C94 Transporter BF17_14895 ENOG4105CN8 Transcriptional regulator BF17_14905 ENOG4107U5R The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity) BF17_14910 ENOG4105EAA nucleoside BF17_14920 ENOG4105BZU Histidine kinase BF17_14930 ENOG4107QWP ABC-2 type transporter BF17_14935 ENOG4107QWP ABC-2 type transporter BF17_14940 ENOG4105CJ1 ABC, transporter BF17_14950 ENOG4107MVR Transcriptional regulator BF17_14955 ENOG4105C1J atp-dependent rna helicase BF17_14960 ENOG4105EQR Transposase IS116 IS110 IS902 BF17_14995 ENOG4105C1J atp-dependent rna helicase BF17_15005 ENOG4105FBT Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity) BF17_15020 ENOG41061WM D-Alanyl-D-Alanine BF17_15025 ENOG4105CXG d-lactate dehydrogenase BF17_15035 ENOG4105N1F Hnh endonuclease BF17_15045 ENOG4105Y3U Transglycosylase-associated protein BF17_15055 ENOG4106ZX3 phosphonate ABC transporter, periplasmic phosphonate-binding protein BF17_15070 ENOG4108W15 Protein of unknown function (DUF1456) BF17_15080 ENOG4105C32 Amino acid ABC transporter (Permease) BF17_15085 ENOG4105CNN ABC, transporter BF17_15090 ENOG4108JJB ABC transporter BF17_15095 ENOG4108IV0 ABC, transporter BF17_15110 ENOG4105KHC sulfurtransferase BF17_15115 ENOG4107SI7 Substrate-binding region of abc-type glycine betaine transport system BF17_15120 ENOG4107T5X Binding-protein-dependent transport systems, inner membrane component BF17_15125 ENOG4108IJ8 ABC transporter BF17_15130 ENOG4105WJV Binding-protein-dependent transport systems, inner membrane component BF17_15135 ENOG4105D5Q Arginine ornithine antiporter BF17_15140 ENOG4105CXN decarboxylase BF17_15150 ENOG4105FDR Membrane BF17_15165 ENOG4105DVT helicase BF17_15185 ENOG4108UII YfaZ family BF17_15190 ENOG4105E0U tyrosine-specific transport protein BF17_15205 ENOG4105XPH Ferredoxin BF17_15210 ENOG4105E05 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF17_15215 ENOG4105BZH Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity) BF17_15225 ENOG4105C24 DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity) BF17_15235 ENOG4105BZU Histidine kinase BF17_15240 ENOG41068CG regulatoR BF17_15245 ENOG4105E3G Phosphotransfer intermediate protein in two-component regulatory system with RcsBC BF17_15250 ENOG4106UW1 Major Facilitator superfamily BF17_15260 ENOG4105FCK Membrane BF17_15285 ENOG4107R6D beta-lactam binding protein AmpH BF17_15290 ENOG4105CT4 transporter BF17_15300 ENOG4105C8Q Methyl-accepting chemotaxis BF17_15310 ENOG4105Y50 Virulence Protein BF17_15320 ENOG4105HRS Antitermination protein BF17_15325 ENOG4105G63 Type III effector Hrp-dependent BF17_15335 ENOG4105MVE transcriptional regulator BF17_15365 ENOG4105TKZ Tail Sheath BF17_15405 ENOG4108T86 baseplate J family protein BF17_15420 ENOG4108Q3X Transcriptional regulator BF17_15430 ENOG4105CS2 ec 3.2.1.21 BF17_15450 ENOG4105E68 Sulfatase BF17_15455 ENOG4105PAN UPF0352 protein BF17_15470 ENOG4105CFI type iii restriction protein res subunit BF17_15475 ENOG4105I08 Pseudouridine synthase BF17_15480 ENOG4105C2C drug resistance transporter, Bcr CflA BF17_15485 ENOG4105HG6 BF17_15490 ENOG4108JQ5 ABC transporter BF17_15495 ENOG4108IYQ Binding-protein-dependent transport systems inner membrane component BF17_15500 ENOG4108I5X binding-protein-dependent transport systems inner membrane Component BF17_15505 ENOG4105E43 Extracellular solute-binding protein, family 5 BF17_15510 ENOG4105CXC rtn protein BF17_15525 ENOG4107TT5 NLP P60 protein BF17_15530 ENOG41076MN Phosphoesterase, PA-phosphatase related BF17_15535 ENOG4105CKI cobalamin synthesis protein BF17_15550 ENOG4107YCY Transcriptional regulator BF17_15555 ENOG4105DEI Mannitol dehydrogenase BF17_15575 ENOG4105KRS Proteinase inhibitor BF17_15580 ENOG4105CHR reductase BF17_15595 ENOG4105C26 Dehydrogenase BF17_15615 ENOG4105E66 phosphoriboisomerase A BF17_15625 ENOG4105C2J ABC transporter BF17_15640 ENOG4105DTZ bifunctional PTS system fructose-specific transporter subunit IIA HPr protein BF17_15645 ENOG4105DE4 1-phosphofructokinase BF17_15650 ENOG4105DM4 PTS System BF17_15655 ENOG4108SGD regulatory protein BF17_15670 ENOG4108UIF Chaperone BF17_15690 ENOG4105HMI Membrane BF17_15695 ENOG4105DUM transcriptional regulator, lysR family BF17_15700 ENOG4108IQI permease BF17_15710 ENOG4105EHG Permease protein BF17_15720 ENOG4105D05 Receptor BF17_15725 ENOG4108TGY Glutathione S-transferase BF17_15740 ENOG4105D01 (LipO)protein BF17_15750 ENOG4108UMI ABC transporter, permease BF17_15755 ENOG4105DZ1 carboxypeptidase BF17_15775 ENOG4107FB0 transcriptional regulator DeoR family BF17_15785 ENOG4105D1E Undecaprenyl pyrophosphate phosphatase BF17_15800 ENOG4105D0C transport protein BF17_15805 ENOG41090BQ Glutaredoxin BF17_15815 ENOG4105X20 member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress BF17_15820 ENOG4108RMJ sensory transduction regulator BF17_15825 ENOG4107RUE extracellular solute-binding protein family 1 BF17_15830 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF17_15835 ENOG4105F38 ABC transporter, permease BF17_15840 ENOG4105D38 putrescine abc transporter BF17_15845 ENOG4105RBQ inner membrane protein ybjO BF17_15855 ENOG4106TNF Periplasmic binding protein BF17_15870 ENOG4105D13 transposase BF17_15900 ENOG4108I9K permease protein BF17_15905 ENOG4105E0A ABC, transporter BF17_15910 ENOG410642S Nicotianamine synthase protein BF17_15915 ENOG4108MRU Uncharacterized protein conserved in bacteria (DUF2338) BF17_15920 ENOG4108I0N Transporter, RarD family, DMT superfamily protein BF17_15925 ENOG4105DMR ABC, transporter BF17_15930 ENOG4105GBT ABC transporter BF17_15935 ENOG4106PMH Extracellular solute-binding protein family 3 BF17_15940 ENOG4105E5Z arginine transporter ATP-binding subunit BF17_15945 ENOG4105G7T Catalyzes the Claisen rearrangement of chorismate to prephenate (By similarity) BF17_15950 ENOG41064MM (LipO)protein BF17_15955 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BF17_15960 ENOG4105CGD Nad-dependent epimerase dehydratase BF17_15965 ENOG4105C5W Aldolase BF17_15970 ENOG4105C7K acetolactate synthase BF17_15975 ENOG4105CJJ Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity) BF17_15985 ENOG4105DWU Membrane BF17_15990 ENOG4105CPB ATP-dependent endonuclease of the OLD family BF17_15995 ENOG4108MJ5 VirK protein BF17_16005 ENOG4105DJY efflux transporter, rnd family, mfp subunit BF17_16015 ENOG4105VEQ Cold shock protein BF17_16025 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BF17_16030 ENOG4105K9U however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity) BF17_16040 ENOG4108JJ8 (ABC) transporter BF17_16045 ENOG4108JJ9 ABC, transporter BF17_16050 ENOG4105C3M thioredoxin reductase BF17_16055 ENOG4105EW9 transcriptional regulator AsnC family BF17_16075 ENOG4105D1H recombination factor protein RarA BF17_16085 ENOG4108ISG Major Facilitator BF17_16090 ENOG4105F1A Pyruvate formate-lyase BF17_16100 ENOG4105C6N Formate acetyltransferase BF17_16105 ENOG4105TMB Formate nitrite transporter BF17_16110 ENOG4105DDY UPF0142 protein ycaO BF17_16115 ENOG4105HDK L-asparaginase BF17_16145 ENOG4105CAV thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity) BF17_16160 ENOG4108EQH DNA internalization-related competence protein ComEC Rec2 BF17_16175 ENOG4105E32 cytoplasmic protein BF17_16180 ENOG4105VEQ Cold shock protein BF17_16185 ENOG4105W49 UPF0434 protein BF17_16195 ENOG4107VR7 transferase activity, transferring phosphorus-containing groups BF17_16205 ENOG4106371 Methyltransferase BF17_16210 ENOG4105GHU Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity (By similarity) BF17_16215 ENOG4105DAH Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF (By similarity) BF17_16270 ENOG4105DIT ErfK YbiS YcfS YnhG family protein BF17_16275 ENOG4105EAQ (twin-arginine translocation) pathway signal BF17_16280 ENOG4105C5X domain protein BF17_16285 ENOG4105CGF Aromatic amino acid aminotransferase BF17_16310 ENOG4105CD8 aminopeptidase N BF17_16320 ENOG4108T7E Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ (By similarity) BF17_16325 ENOG4105QVC MOSC domain-containing protein BF17_16335 ENOG4105C5H ABC transporter BF17_16340 ENOG4105F1S paraquat-inducible protein a BF17_16345 ENOG4105DY2 Paraquat-inducible protein b BF17_16350 ENOG4108Q2G (LipO)protein BF17_16355 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BF17_16370 ENOG4105DAN ATP-dependent protease BF17_16380 ENOG4105UYK outer membrane protein a BF17_16390 ENOG4108RZ1 DNA transformation protein BF17_16395 ENOG4105EM2 membrane BF17_16400 ENOG410901E Membrane BF17_16405 ENOG41088T4 Helicase IV BF17_16415 ENOG4108Q67 UPF0319 protein BF17_16420 ENOG4105K4P CoA-binding domain protein BF17_16435 ENOG4108I1J Integrase BF17_16665 ENOG41063XI Toxic component of a toxin-antitoxin (TA) module. A BF17_16670 ENOG4105PF0 Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin BF17_16805 ENOG4108Z0T Part of a sulfur-relay system (By similarity) BF17_16820 ENOG4108YXN Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity) BF17_16825 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BF17_16830 ENOG4105CHR reductase BF17_16835 ENOG4105F99 Hydroxymethylglutaryl-CoA synthase BF17_16845 ENOG4108KQ6 Enoyl-CoA hydratase BF17_16850 ENOG4105CHR reductase BF17_16860 ENOG41062T2 Acyl carrier protein BF17_16865 ENOG4107QKG PfaD family BF17_16880 ENOG4105C5H ABC transporter BF17_16890 ENOG4105D06 uba thif-type nad fad binding protein BF17_16895 ENOG4105CVM Molybdenum cofactor synthesis domain protein BF17_16900 ENOG4105CSH Transporter BF17_16910 ENOG4105C19 ABC transporter BF17_16915 ENOG4105ENT Efflux transporter rnd family, mfp subunit BF17_16940 ENOG4105EGI Transcriptional regulator BF17_16945 ENOG4105CBP Major Facilitator BF17_16955 ENOG4105DHF Membrane BF17_16970 ENOG4108HWV )-transporter BF17_16975 ENOG4107GZ4 SanA protein BF17_16990 ENOG41067MG lrgb family BF17_17000 ENOG4105E5W Transporter BF17_17025 ENOG4105D1F ATP-binding protein BF17_17040 ENOG4108GAE asmA family BF17_17045 ENOG4105EE5 Membrane protein terC BF17_17050 ENOG4108819 ferric iron reductase BF17_17060 ENOG4105F1Y L-lysine 6-monooxygenase (NADPH) BF17_17070 ENOG4105DUU IucA IucC family protein BF17_17075 ENOG4105E0A ABC, transporter BF17_17080 ENOG4105TVJ transport system, permease BF17_17085 ENOG4105DQ5 transport system permease protein BF17_17090 ENOG4105JKQ Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity) BF17_17095 ENOG4105CNM Receptor BF17_17100 ENOG4105DUU IucA IucC family protein BF17_17110 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BF17_17115 ENOG4105C3Y UTP-glucose-1-phosphate uridylyltransferase BF17_17120 ENOG4105C7Q Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity) BF17_17125 ENOG4105K8F Phosphoribosyl-amp cyclohydrolase BF17_17140 ENOG4108UJE IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity) BF17_17145 ENOG4105ECC imidazole-glycerol-phosphate dehydratase BF17_17155 ENOG4105CEK Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity) BF17_17165 ENOG4108535 NAD dependent epimerase/dehydratase family BF17_17175 ENOG4105CNN ABC, transporter BF17_17180 ENOG4105C2J ABC transporter BF17_17185 ENOG4107SCQ Iron-containing alcohol dehydrogenase BF17_17195 ENOG4105CUB amino acid BF17_17200 ENOG4105CJB Exodeoxyribonuclease I BF17_17215 ENOG4105TNG K13735 adhesin invasin BF17_17225 ENOG4105CSP Major Facilitator Superfamily BF17_17230 ENOG4105KIR Thiol-disulfide oxidoreductase dcc BF17_17240 ENOG4105I7Z Short-chain dehydrogenase reductase Sdr BF17_17250 ENOG4105DIA mandelate racemase muconate lactonizing BF17_17270 ENOG4105UQX Mate efflux family protein BF17_17290 ENOG4105IUQ nucleoprotein polynucleotide-associated enzyme BF17_17305 ENOG4105CG6 trap dicarboxylate transporter dctm subunit BF17_17315 ENOG4105DR6 Trap dicarboxylate transporter, dctp subunit BF17_17320 ENOG4108TSE Transferase BF17_17345 ENOG4105BZ1 (ABC) transporter BF17_17370 ENOG4105N4N Protein of unknown function (DUF2766) BF17_17375 ENOG4105TIK BF17_17380 ENOG41064PC BF17_17400 ENOG4105C85 amino acid BF17_17410 ENOG4105VEQ Cold shock protein BF17_17415 ENOG4105DBW Multi-copper polyphenol oxidoreductase laccase BF17_17420 ENOG4105DHI Methyltransferase BF17_17430 ENOG4105BZU Histidine kinase BF17_17450 ENOG4105F3R pts system mannose fructose sorbose family iid BF17_17455 ENOG4105ETZ PTS System BF17_17460 ENOG4108EQA pts system BF17_17465 ENOG4105EE5 Membrane protein terC BF17_17500 ENOG4105C1J atp-dependent rna helicase BF17_17505 ENOG4105X2V dna damage-inducible protein BF17_17520 ENOG4105CUG Oligopeptidase b BF17_17535 ENOG4105MPK DNA polymerase III subunit theta BF17_17540 ENOG41090A1 ferritin BF17_17545 ENOG4105FXM Copper resistance protein BF17_17550 ENOG4108PNC copper resistance BF17_17555 ENOG4105NKT exported protein BF17_17585 ENOG4105D00 flagellar biosynthetic protein flhB BF17_17590 ENOG4105D7B Flagellar biosynthesis protein flha BF17_17595 ENOG4105W13 flagellar protein BF17_17605 ENOG4105QVD Flagella synthesis protein FlgN BF17_17610 ENOG4105M9M anti-sigma28 factor FlgM BF17_17615 ENOG4105CKS Flagella basal body P-ring formation protein flgA BF17_17620 ENOG4105K88 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity) BF17_17625 ENOG4108ZC9 flagellar basal-body rod protein flgc BF17_17630 ENOG4105W00 Flagellar hook capping protein BF17_17635 ENOG4105BZE flagellar hook protein, FlgE BF17_17640 ENOG4108KPB Flagellar basal-body rod protein FlgF BF17_17645 ENOG4105CGA flagellar basal-body rod protein FlgG BF17_17660 ENOG4108ZW7 flagellar rod assembly protein muramidase flgj BF17_17665 ENOG4105E1Q flagellar hook-associated protein BF17_17670 ENOG4105DTJ flagellar hook-associated protein BF17_17675 ENOG4105DKT Transcriptional regulator BF17_17685 ENOG4105CNN ABC, transporter BF17_17695 ENOG4105C2J ABC transporter BF17_17705 ENOG4108MGF sugar kinase BF17_17715 ENOG4105D19 Role in flagellar biosynthesis (By similarity) BF17_17720 ENOG4105VS8 Flagellar biosynthetic protein fliq BF17_17725 ENOG4105CN7 Flagellar biosynthetic protein FliP BF17_17735 ENOG4105DD5 Flagellar motor switch protein BF17_17740 ENOG4105D24 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BF17_17745 ENOG4107ZI8 flagellar basal body-associated protein flil BF17_17750 ENOG4105WF4 Flagellar hook-length control protein BF17_17755 ENOG4105GSA Flagellar export protein flij BF17_17760 ENOG4108JIR Flagellum-specific ATP synthase BF17_17765 ENOG41090PJ Flagellar assembly protein BF17_17770 ENOG4105CS3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity) BF17_17775 ENOG4105C1F The M ring may be actively involved in energy transduction (By similarity) BF17_17780 ENOG4105VQ0 flagellar hook-basal body complex protein fliE BF17_17805 ENOG4105DHT Metal Dependent Phosphohydrolase BF17_17820 ENOG4105MQ3 flagellar protein FliS BF17_17825 ENOG4105DTS flagellar hook-associated BF17_17840 ENOG4105DN4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity) BF17_17845 ENOG4108M9K flagella biosynthesis protein FliZ BF17_17850 ENOG4105K6H D-cysteine desulfhydrase BF17_17855 ENOG4105EAB amino acid AbC transporter BF17_17860 ENOG4105E5Q amino acid AbC transporter BF17_17865 ENOG4105CDA abc transporter atp-binding protein BF17_17885 ENOG4105C26 Dehydrogenase BF17_17890 ENOG4105CK7 Sodium proline symporter BF17_17920 ENOG4105C85 amino acid BF17_17930 ENOG4108T1M outer membrane protein x BF17_17940 ENOG4105XVG cytoplasmic protein BF17_17945 ENOG4105WH1 Two component transcriptional regulator luxr family BF17_18120 ENOG4105DH7 May be involved in recombination (By similarity) BF17_18150 ENOG4105RWQ Protein of unknown function (DUF1364) BF17_18175 ENOG4105QFS Lysis protein S homolog from lambdoid prophage BF17_18180 ENOG4105KUS lysozyme BF17_18260 ENOG4105UZW Tail fiber assembly protein BF17_18290 ENOG4108WC9 type VI secretion system effector, hcp1 family BF17_18370 ENOG4108MQF Chaperone BF17_18380 ENOG4105CW0 outer membrane usher protein BF17_18415 ENOG4108Q9V regulatoR BF17_18430 ENOG4105CYC Transferase BF17_18435 ENOG4105DJG MaoC domain protein dehydratase BF17_18460 ENOG4106MMI NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity) BF17_18465 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BF17_18470 ENOG4105C85 amino acid BF17_18475 ENOG4105MVE transcriptional regulator BF17_18495 ENOG4105CSV Glutaminase BF17_18505 ENOG4107SJW iron permease, FTR1 BF17_18520 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BF17_18530 ENOG4105D6C Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity) BF17_18550 ENOG4105H1N peptidase, M24 BF17_18555 ENOG4108TUY outer membrane protein PgaA BF17_18560 ENOG4107BJW polysaccharide deacetylase BF17_18565 ENOG4105CND Glycosyl transferase, family 2 BF17_18590 ENOG4105D5M phosphate starvation-inducible protein BF17_18595 ENOG4105EWV Sodium calcium exchanger membrane region BF17_18600 ENOG4105BZU Histidine kinase BF17_18610 ENOG4105CFY cytochrome d ubiquinol oxidase, subunit ii BF17_18615 ENOG4105C4M (Ubiquinol oxidase) subunit I BF17_18620 ENOG4105C1I TRANSCRIPTIONAl REGULATOR GntR family BF17_18680 ENOG4105CZE histidine utilization repressor BF17_18690 ENOG41090B9 response to stress BF17_18710 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BF17_18745 ENOG4107VBM 3-beta hydroxysteroid dehydrogenase isomerase BF17_18795 ENOG4108WF3 methyltransferase BF17_18860 ENOG4105GR3 Histidine kinase BF17_18885 ENOG4105ENX hydrolase BF17_18935 ENOG4105CNU cell division protein FtsK BF17_18950 ENOG4105HVQ Regulatory factor of maltose metabolism BF17_18970 ENOG4108YGG dna repair protein BF17_18975 ENOG4105C13 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity) BF17_19020 ENOG4105DFP Integrase BF17_19025 ENOG4105C3G gtp-binding protein BF17_19035 ENOG4105MGX transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria BF17_19045 ENOG4105C5T Phosphoribosyl pyrophosphate synthase BF17_19085 ENOG4108YY7 Invasion gene expression up-regulator SirB BF17_19090 ENOG41063JG Transcriptional regulator BF17_19100 ENOG4105CHH sulfate transporter BF17_19125 ENOG4105JPG D-isomer specific 2-hydroxyacid dehydrogenase BF17_19135 ENOG4107XHZ cytoplasmic chaperone TorD family protein BF17_19140 ENOG4105F3T (LipO)protein BF17_19150 ENOG4105D9U N-acetyltransferase BF17_19160 ENOG4105EP9 oxidoreductase BF17_19165 ENOG4105CJR Integral membrane protein (MviN BF17_19185 ENOG4106ZCM YecM protein BF17_19205 ENOG4105WJG Glutathione BF17_19210 ENOG41081XQ Conserved Protein BF17_19220 ENOG4108TIT dATP pyrophosphohydrolase BF17_19245 ENOG4105FAV ABC, transporter BF17_19255 ENOG4105NXV High-affinity zinc uptake system protein BF17_19260 ENOG4105DR5 peptidase BF17_19265 ENOG4105NWR lipid A biosynthesis (Kdo)2-(Lauroyl)-lipid IVA acyltransferase BF17_19270 ENOG4105CA9 Pyruvate kinase BF17_19275 ENOG4106KNT transcriptional regulator BF17_19280 ENOG4105D8W glucose-6-phosphate 1-dehydrogenase BF17_19285 ENOG4108UHU Aldolase BF17_19300 ENOG4105M4H endoribonuclease L-psp BF17_19305 ENOG4105DVT helicase BF17_19310 ENOG41072GX Peptidase M22 Glycoprotease BF17_19315 ENOG4105Y4Z Outer Membrane Lipoprotein BF17_19320 ENOG4105CEY Amp-dependent synthetase and ligase BF17_19325 ENOG4105ZIE Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity) BF17_19330 ENOG4105VJP Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity) BF17_19335 ENOG4107QMS site-determining protein BF17_19350 ENOG4105CVE Lytic murein transglycosylase BF17_19355 ENOG4105FBJ fumarylacetoacetate (faa) hydrolase BF17_19370 ENOG4105C3J Cysteine desulfurase BF17_19410 ENOG4105ED1 spovr family BF17_19420 ENOG4105CNH Multidrug resistance protein MdtL BF17_19445 ENOG4105CYN Serine protein kinase BF17_19450 ENOG4105GNX MltA-interacting MipA family protein BF17_19455 ENOG4105DSB aldose 1-epimerase BF17_19470 ENOG4105VUT cytoplasmic protein BF17_19475 ENOG4108RWI nicotinamidase BF17_19480 ENOG4105HDK L-asparaginase BF17_19485 ENOG4105D07 Signal peptide peptidase, SppA BF17_19490 ENOG41069NU Nitroreductase BF17_19500 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BF17_19505 ENOG4105MTM Protein of unknown function (DUF1496) BF17_19510 ENOG4105M6F mutator MutT protein BF17_19515 ENOG4105CGK Exodeoxyribonuclease III BF17_19520 ENOG4105SKE transcriptional Regulator LysR family BF17_19535 ENOG4105CIY formyltetrahydrofolate deformylase BF17_19545 ENOG4105I93 response regulator BF17_19565 ENOG4105CMM transposase BF17_19570 ENOG4107104 thymidine kinase BF17_19575 ENOG4108EKI Dehydrogenase BF17_19580 ENOG4105EZI multiple antibiotic resistance (MarC)-related protein BF17_19585 ENOG4107QSI ABC, transporter BF17_19595 ENOG4105C2T Binding-protein-dependent transport systems, inner membrane component BF17_19600 ENOG4105C3U ABC transporter BF17_19605 ENOG4108JQ7 (ABC) transporter BF17_19630 ENOG4105K9H YciI-like protein BF17_19635 ENOG410822N TonB family BF17_19640 ENOG4105NAU thioesterase Superfamily protein BF17_19660 ENOG4105EIF outer membrane protein W BF17_19680 ENOG4105DK0 Indole-3-glycerol phosphate synthase BF17_19690 ENOG4105DDQ anthranilate synthase BF17_19715 ENOG4107RTD sua5 ycio yrdc ywlc family protein BF17_19720 ENOG4105FE9 pseudouridine synthase BF17_19725 ENOG41068B1 Cob-I-yrinic acid a,c-diamide adenosyltransferase BF17_19730 ENOG4105UBK short-chain dehydrogenase reductase BF17_19735 ENOG4105ERU peptidase BF17_19740 ENOG4105RKX Protein of unknown function (DUF2498) BF17_19745 ENOG4105C73 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity) BF17_19750 ENOG4107R11 Transcriptional regulator BF17_19760 ENOG4107QM5 aconitate hydratase BF17_19765 ENOG4107T1C Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity) BF17_19770 ENOG4105EYK Phosphatidylglycerophosphatase B BF17_19775 ENOG4105Q4A inner membrane protein yciS BF17_19780 ENOG4105CFV Tetratricopeptide repeat protein BF17_19795 ENOG4108ZJT translation initiation factor, Sui1 BF17_19800 ENOG41061RM osmotically inducible lipoprotein BF17_19805 ENOG4107R0P L-ribulose-5-phosphate 4-epimerase BF17_19820 ENOG4105VCD cytoplasmic protein BF17_19825 ENOG4105D22 carbon starvation protein BF17_19840 ENOG4105CSP Major Facilitator Superfamily BF17_19845 ENOG4105EXW epimerase dehydratase BF17_19850 ENOG4105CSM endonuclease III BF17_19860 ENOG4108UQQ Electron transport complex BF17_19870 ENOG4105UEI Transcriptional Regulator AraC Family BF17_19890 ENOG4105M9B inner membrane protein ydgK BF17_19895 ENOG4108JJA ABC, transporter BF17_19910 ENOG4108JJA ABC, transporter BF17_19925 ENOG4105DMK Periplasmic binding protein LacI transcriptional regulator BF17_19935 ENOG4105CNN ABC, transporter BF17_19945 ENOG4105D9R oxidoreductase BF17_19950 ENOG4105DHU Bile acid BF17_19965 ENOG4105FDP GntR family transcriptional regulator BF17_19970 ENOG4106J39 exported protein BF17_19975 ENOG4105EIP mannose-6-phosphate isomerase BF17_19995 ENOG4105D94 Major Facilitator Superfamily BF17_20005 ENOG4106NZI LysR family Transcriptional regulator BF17_20010 ENOG4105DAG ROK family BF17_20015 ENOG4105EWW Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity) BF17_20025 ENOG4105KBG Protein of unknown function (DUF1161) BF17_20035 ENOG4105EMU Dehydrogenase BF17_20040 ENOG4108JU9 GAF modulated sigma54 specific transcriptional regulator Fis family BF17_20045 ENOG4105C26 Dehydrogenase BF17_20050 ENOG4105DWP Membrane BF17_20075 ENOG4105DFD Na H antiporter BF17_20080 ENOG41060NJ transcriptional regulator BF17_20090 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BF17_20095 ENOG4105CNN ABC, transporter BF17_20100 ENOG4105C2J ABC transporter BF17_20110 ENOG4107UWC ABC, transporter BF17_20115 ENOG4105EFS Binding-protein-dependent transport systems, inner membrane component BF17_20125 ENOG4105FYV Amp nucleosidase BF17_20150 ENOG4105C7K acetolactate synthase BF17_20155 ENOG4105M71 acetolactate synthase 1 regulatory subunit BF17_20160 ENOG4105PAD Hydrolase BF17_20175 ENOG4105K85 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity) BF17_20180 ENOG4105DS0 Transcriptional regulator, Crp Fnr family BF17_20185 ENOG4105Q9Y Universal stress protein BF17_20190 ENOG4105C15 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BF17_20195 ENOG4108IIE The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity) BF17_20200 ENOG4105C5D exported protein BF17_20205 ENOG4105D5Q Arginine ornithine antiporter BF17_20215 ENOG4107EXC regulatoR BF17_20220 ENOG4105JJR Histidine kinase BF17_20225 ENOG4105CTD carboxy-peptidase BF17_20240 ENOG4105DS1 cytochrome b561 BF17_20255 ENOG4105CVW peptidase s1 and s6 chymotrypsin hap BF17_20270 ENOG4105CQ7 ATP-dependent helicase BF17_20280 ENOG4105DKT Transcriptional regulator BF17_20285 ENOG4105DEI Mannitol dehydrogenase BF17_20290 ENOG4105WXT Conserved Protein BF17_20295 ENOG410689M (LipO)protein BF17_20300 ENOG4107H52 Dicarboxylate transport BF17_20325 ENOG41090X5 Heat shock protein hslJ BF17_20340 ENOG4105D95 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity) BF17_20355 ENOG4107QSI ABC, transporter BF17_20360 ENOG4105KXI murein peptide amidase A BF17_20365 ENOG4107S8C mandelate racemase muconate lactonizing BF17_20370 ENOG4108V1J Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity) BF17_20395 ENOG4105CM6 amino acid regulated cytosolic protein BF17_20405 ENOG4105FM1 phage shock protein C BF17_20410 ENOG4105YYT phage shock protein B BF17_20415 ENOG41087YS Phage shock protein A BF17_20420 ENOG4105E51 psp operon transcriptional activator BF17_20425 ENOG4108HIY periplasmic BF17_20430 ENOG4108I5W peptide transport system, permease protein BF17_20435 ENOG4108EU3 peptide transport system, permease BF17_20440 ENOG4108JQ3 Peptide ABC transporter ATP-binding protein BF17_20445 ENOG4108JQ2 peptide transport system atp-binding protein BF17_20450 ENOG4105Q4T oxidoreductase BF17_20455 ENOG4105DUX Transporter BF17_20465 ENOG41069YE inner membrane protein yohC BF17_20470 ENOG4108ZR5 Conserved Protein BF17_20480 ENOG4108K3A Glutathione S-transferase BF17_20500 ENOG410642K Lysozyme inhibitor BF17_20510 ENOG4108XTF Outer Membrane Lipoprotein BF17_20520 ENOG4107RGM aldo keto reductase BF17_20525 ENOG4105XZD Fe-S protein BF17_20530 ENOG4105DIJ Phosphoethanolamine transferase BF17_20535 ENOG4108WUH Transcriptional regulator, TetR family BF17_20540 ENOG4105CCY NADH flavin oxidoreductase, NADH oxidase BF17_20550 ENOG4108UYE Lactoylglutathione lyase BF17_20560 ENOG4105M2J Glutaredoxin BF17_20565 ENOG4105K4H Nlp p60 protein BF17_20570 ENOG4105CK4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity) BF17_20585 ENOG4105F52 Transcriptional regulator BF17_20590 ENOG4105CZQ inner membrane transport protein YdhC BF17_20595 ENOG4105CV9 cyclopropane-fatty-acyl-phospholipid synthase BF17_20600 ENOG4108R6K riboflavin synthase, subunit alpha BF17_20625 ENOG4105CA9 Pyruvate kinase BF17_20630 ENOG4105KMX major outer membrane lipoprotein BF17_20635 ENOG4107N1Q ErfK YbiS YcfS YnhG family protein BF17_20650 ENOG4105JRK feS assembly protein SufD BF17_20655 ENOG4105C3K feS assembly ATPase SufC BF17_20660 ENOG4105DIW FeS assembly protein SUFB BF17_20665 ENOG4108Z4V iron-sulfur cluster assembly BF17_20670 ENOG4105KA0 thioesterase Superfamily protein BF17_20685 ENOG4105IPI Membrane BF17_20690 ENOG4108HRN Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity) BF17_20700 ENOG4105E99 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity) BF17_20715 ENOG4108QBX (LipO)protein BF17_20755 ENOG41080WI Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system (By similarity) BF17_20760 ENOG4108V06 Glutathione peroxidase BF17_20770 ENOG4108ZUF This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity) BF17_20815 ENOG41087WU BF17_20835 ENOG4105DSE periplasmic solute binding protein BF17_20840 ENOG4105DIK (ABC) transporter BF17_20845 ENOG4105CC5 ABC transporter BF17_20850 ENOG4105CC5 ABC transporter BF17_20860 ENOG4105CMM transposase BF17_20865 ENOG4105FGM Fructosamine kinase BF17_20870 ENOG4107PN8 YfeABCD locus regulator BF17_20900 ENOG4107UW8 HAD-superfamily hydrolase subfamily IA variant 3 BF17_20905 ENOG4105M5J Cupin 2, conserved barrel domain protein BF17_20915 ENOG4105CHR reductase BF17_20920 ENOG41061NF Pectate lyase BF17_20925 ENOG4105DB9 Binding-protein-dependent transport systems inner membrane component BF17_20930 ENOG4105F66 Binding-protein-dependent transport systems inner membrane component BF17_20940 ENOG4105WEM extracellular solute-binding protein BF17_20945 ENOG4108PU9 oligogalacturonate-specific porin BF17_20950 ENOG4107K5X Membrane-bound metal-dependent hydrolase BF17_20955 ENOG4108ETY sodium dicarboxylate symporter BF17_20960 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BF17_20970 ENOG4105CAZ oligogalacturonide lyase BF17_20975 ENOG4105C0R drug resistance transporter emrb qaca subfamily BF17_20980 ENOG4108VEV chaperone BF17_20995 ENOG4108VEV chaperone BF17_21000 ENOG4106UBK fimbrial-like adhesin protein BF17_21010 ENOG4105CN1 protease BF17_21020 ENOG4108ZGC gaf domain protein BF17_21025 ENOG4105H2K paraquat-inducible protein a BF17_21070 ENOG4105WT8 Protein of unknown function (DUF1480) BF17_21095 ENOG4108YYQ gCN5-related N-acetyltransferase BF17_21115 ENOG4105CJ4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity) BF17_21135 ENOG4105EUR Domain-Containing protein BF17_21160 ENOG4105EUR Domain-Containing protein BF17_21165 ENOG4108VBV N-Acetylmuramoyl-L-alanine amidase BF17_21170 ENOG4108KCC Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity) BF17_21175 ENOG4108VYJ response regulator receiver protein BF17_21185 ENOG4105BZU Histidine kinase BF17_21190 ENOG4105C8Q Methyl-accepting chemotaxis BF17_21210 ENOG4108V3W Chemotaxis protein, CheW BF17_21215 ENOG4105CBS Chea signal transduction histidine kinase BF17_21225 ENOG4107RD7 Flagellar Motor Protein, MotA BF17_21230 ENOG4106CIA Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region BF17_21240 ENOG4105C52 Atpase, p-type (Transporting), had superfamily, subfamily ic BF17_21245 ENOG4105KT7 mgtC SapB transporter BF17_21250 ENOG4105C8Q Methyl-accepting chemotaxis BF17_21260 ENOG4105VEQ Cold shock protein BF17_21275 ENOG4105GSJ Inner membrane protein ylaC BF17_21280 ENOG4108XM1 transcriptional regulator AsnC family BF17_21290 ENOG41061EV selenium-binding protein YdfZ BF17_21295 ENOG4105D6F Phosphatase BF17_21300 ENOG4108IQK o-acetylhomoserine BF17_21305 ENOG4107RHT methyl-accepting chemotaxis sensory transducer with Pas Pac sensor BF17_21315 ENOG4106NDP Transcriptional regulator BF17_21320 ENOG4108HMX isocitrate dehydrogenase (NADP) BF17_21360 ENOG4108X9F tail fiber protein BF17_21365 ENOG4105K64 Glycosyl transferase, family 2 BF17_21370 ENOG4105UZW Tail fiber assembly protein BF17_21375 ENOG410685N tail fiber protein BF17_21465 ENOG4105HRS Antitermination protein BF17_21470 ENOG4105RWQ Protein of unknown function (DUF1364) BF17_21530 ENOG4105XB7 anti-repressor protein BF17_21560 ENOG4108I1J Integrase BF17_21565 ENOG4108HMX isocitrate dehydrogenase (NADP) BF17_21570 ENOG4108R99 pseudouridine synthase BF17_21590 ENOG4107QTF adenylosuccinate lyase BF17_21600 ENOG4105XJC Two component transcriptional regulator (Winged helix family BF17_21610 ENOG4105EZE Cupin 4 family protein BF17_21620 ENOG4105NDF NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity) BF17_21630 ENOG4105D60 lipoprotein releasing system transmembrane protein BF17_21640 ENOG4105D60 lipoprotein releasing system transmembrane protein BF17_21645 ENOG4108JA2 transcriptioN-repair coupling factor BF17_21650 ENOG4107MBR 17 kDa surface antigen BF17_21665 ENOG4105CEP NADH dehydrogenase BF17_21690 ENOG41090DQ Lipoprotein BF17_21695 ENOG4105K59 histidine triad (HIT) protein BF17_21700 ENOG4105F9E Shikimate 5-dehydrogenase BF17_21705 ENOG4105CI1 PTS System BF17_21710 ENOG4105F8V Hydrolase, tatD family BF17_21715 ENOG4107QRG dna polymerase iii BF17_21725 ENOG4105HHA aminodeoxychorismate lyase BF17_21730 ENOG4105YAZ 4-amino-4-deoxychorismate lyase BF17_21735 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BF17_21745 ENOG4105CHR reductase BF17_21750 ENOG4105CJF Malonyl coA-acyl carrier protein transacylase BF17_21765 ENOG4105VGS 50s ribosomal protein l32 BF17_21770 ENOG4105FCQ metal-binding, possibly nucleic acid-binding protein BF17_21780 ENOG4105EI2 Pseudouridine synthase BF17_21785 ENOG4107QQB Ribonuclease E BF17_21805 ENOG4105PVA Biofilm formation regulatory protein BssS BF17_21820 ENOG4105DSF transport protein BF17_21850 ENOG4105D1S lipid A biosynthesis BF17_21855 ENOG4105DUX Transporter BF17_21860 ENOG4105NAC (LipO)protein BF17_21865 ENOG4105C3A Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity) BF17_21870 ENOG4105DJ9 glucan biosynthesis protein BF17_21905 ENOG4105VJY transcriptional regulator BF17_21915 ENOG4108Y1S CRISPR-associated protein, Csy4 family BF17_21920 ENOG4105M6W Crispr-associated protein, Csy3 family BF17_21925 ENOG4105DZX CRISPR-associated protein, Csy2 family BF17_21930 ENOG4105ENG CRISPR-associated protein, Csy1 family BF17_21935 ENOG4107IIZ CRISPR-associated helicase, Cas3 BF17_21940 ENOG4107SV5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity) BF17_21945 ENOG4105CUY Mechanosensitive ion channel BF17_21965 ENOG4105HY2 Glycosidase related protein BF17_21970 ENOG4105DRS transport system, permease BF17_21985 ENOG4105ETE Transcriptional regulator (LacI family BF17_21995 ENOG4108IJ9 (ABC) transporter BF17_22020 ENOG4105CKT filamentous hemagglutinin BF17_22050 ENOG4105CKT filamentous hemagglutinin BF17_22060 ENOG4105CKT filamentous hemagglutinin BF17_22075 ENOG4105CKT filamentous hemagglutinin BF17_22080 ENOG4105CKT filamentous hemagglutinin BF17_22090 ENOG4105CKT filamentous hemagglutinin BF17_22110 ENOG4105E3J oxidoreductase BF17_22115 ENOG4105DVW rieske (2Fe-2S) BF17_22120 ENOG4105C94 Transporter BF17_22125 ENOG4105C0C Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity) BF17_22135 ENOG4105FKQ transcriptional regulator BF17_22140 ENOG4105CNN ABC, transporter BF17_22145 ENOG4105C2J ABC transporter BF17_22150 ENOG4105E9V Periplasmic binding protein LacI transcriptional regulator BF17_22155 ENOG4105CPQ Dehydrogenase BF17_22175 ENOG4108T1M outer membrane protein x BF17_22215 ENOG4107R0W ABC transporter BF17_22220 ENOG4105E5Q amino acid AbC transporter BF17_22225 ENOG4105CDA abc transporter atp-binding protein BF17_22230 ENOG4107SDU Methyl-accepting chemotaxis BF17_22250 ENOG4108MTB glycosyl transferase family BF17_22265 ENOG4108IPT Naphthoate synthase BF17_22280 ENOG4105E4F Isochorismate synthase BF17_22290 ENOG4105TNS Conserved Protein BF17_22295 ENOG4105C01 Dihydroxy-acid dehydratase BF17_22300 ENOG4105F32 YngK protein BF17_22310 ENOG4105KHV Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity) BF17_22325 ENOG4105C8S subunit m BF17_22330 ENOG4105D65 subunit l BF17_22340 ENOG4107UFS subunit j BF17_22355 ENOG4108IEH NADH dehydrogenase subunit g BF17_22360 ENOG4107QIZ NADH dehydrogenase BF17_22365 ENOG4105GKE subunit e BF17_22390 ENOG4107NQ8 LysR family Transcriptional regulator BF17_22400 ENOG4105CHM Aminotransferase BF17_22415 ENOG4107QWE )-transporter BF17_22420 ENOG4105EVE HAD-superfamily hydrolase subfamily IA variant 3 BF17_22440 ENOG4105C6K Malic enzyme BF17_22445 ENOG4107P2S Transcriptional regulator BF17_22460 ENOG4105CZC PTS system ascorbate-specific transporter subunit IIC BF17_22465 ENOG4105PTV Nudix Hydrolase BF17_22470 ENOG4108RE9 Phosphodiesterase BF17_22475 ENOG4108TC0 Diguanylate phosphodiesterase BF17_22485 ENOG4105ECP epimerase BF17_22490 ENOG4108JEH abc transporter atp-binding protein BF17_22495 ENOG4106YG3 ABC transporter BF17_22500 ENOG4105DSP amino acid AbC transporter BF17_22505 ENOG4105E89 ABC transporter BF17_22510 ENOG4108UMA 3-octaprenyl-4-hydroxybenzoate carboxy-lyase BF17_22515 ENOG4105CBA glutamine phosphoribosylpyrophosphate amidotransferase BF17_22520 ENOG4105E96 Colicin v production protein BF17_22525 ENOG4108S3P Sporulation domain protein BF17_22530 ENOG4105DPM folylpolyglutamate synthase Dihydrofolate synthase BF17_22540 ENOG4105DQR SNARE associated Golgi BF17_22550 ENOG4105CM3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity) BF17_22565 ENOG410631K Membrane BF17_22570 ENOG4106WZ1 flagella biosynthesis regulator BF17_22585 ENOG4105BZU Histidine kinase BF17_22590 ENOG4105C0Q Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity) BF17_22600 ENOG4105MH2 YfcL protein BF17_22605 ENOG4108BPE -transporting atpase BF17_22610 ENOG4105EJ9 Membrane BF17_22625 ENOG4105C76 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity) BF17_22640 ENOG4108BY2 phosphohistidine phosphatase BF17_22660 ENOG4105KZW UPF0381 protein BF17_22665 ENOG4105CKF membrane protein involved in aromatic hydrocarbon degradation BF17_22670 ENOG410903C (LipO)protein BF17_22675 ENOG4105KWW Biogenesis protein BF17_22680 ENOG4105KWW Biogenesis protein BF17_22685 ENOG4107QX9 Thiol disulfide interChange protein BF17_22690 ENOG4105DA4 cytochrome c-type biogenesis protein BF17_22700 ENOG4105X3C heme exporter protein BF17_22705 ENOG41060IM Heme exporter protein BF17_22710 ENOG4105CA5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity) BF17_22735 ENOG4108V0P LemA family BF17_22745 ENOG4108Z8G Alkylphosphonate utilization operon protein PhnA BF17_22825 ENOG4105CW0 outer membrane usher protein BF17_22835 ENOG4108VEV chaperone BF17_22850 ENOG4105C2Z ATP-dependent CLP protease ATP-binding subunit BF17_22905 ENOG4105CUB amino acid BF17_22910 ENOG4105CVE Lytic murein transglycosylase BF17_22935 ENOG4108WC9 type VI secretion system effector, hcp1 family BF17_22960 ENOG4105QAX Iron-sulfur BF17_22965 ENOG4107KGK dmso reductase anchor subunit BF17_22970 ENOG4108NEM leader-binding protein dmsD BF17_22985 ENOG4108VKM cytochrome b561 BF17_22990 ENOG4105CHM Aminotransferase BF17_22995 ENOG41072TH Protein of unknown function (DUF1479) BF17_23010 ENOG4105C5Q Transcriptional regulator BF17_23015 ENOG4105CPC Aldo Keto reductase BF17_23035 ENOG4105D9N nucleoside BF17_23085 ENOG4105VRT cytoplasmic protein BF17_23100 ENOG4105EXN Sulfate transport protein CysZ BF17_23105 ENOG4105C6T cysteine synthase BF17_23110 ENOG4105KZ7 phosphocarrier protein hpr BF17_23120 ENOG4105C5Y PTS System BF17_23130 ENOG4105E1V na solute symporter BF17_23140 ENOG4105CA1 Removes the N-terminal methionine from nascent proteins (By similarity) BF17_23145 ENOG4105C87 Aminotransferase class I and II BF17_23155 ENOG41062D9 Histidine kinase BF17_23160 ENOG4105DPZ Two component transcriptional regulator (Winged helix family BF17_23165 ENOG4105C6T cysteine synthase BF17_23175 ENOG4105ECW sulfate abc transporter BF17_23180 ENOG4108I5D sulfate abc transporter BF17_23185 ENOG4108J2H Sulfate ABC transporter periplasmic sulfate-binding protein BF17_23195 ENOG4105QEK Transcriptional regulator BF17_23200 ENOG4108R66 Conserved Protein BF17_23220 ENOG4105EZR dyp-type peroxidase family protein BF17_23225 ENOG4105E7K (LipO)protein BF17_23230 ENOG4105H4F exported protein BF17_23245 ENOG4108R6G acetyltransferase BF17_23290 ENOG4105C6K Malic enzyme BF17_23315 ENOG4105CUW cytochrome C-TYPE protein BF17_23320 ENOG4108ZMS Electron transfer subunit of the periplasmic nitrate reductase complex NapAB (By similarity) BF17_23330 ENOG41061Q0 Assembly protein for periplasmic nitrate reductase BF17_23335 ENOG4108ZNS ferredoxin-type protein NapF BF17_23355 ENOG4105BZS acriflavin resistance protein BF17_23360 ENOG4105S2T inner membrane protein YbcI BF17_23365 ENOG4105C4X radical SAM domain protein BF17_23370 ENOG4105ENH Sulfatase BF17_23375 ENOG4105C53 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity) BF17_23380 ENOG4107Z33 ABC transporter, permease BF17_23385 ENOG4106JDA Phosphoglycerate transport regulatory protein PGTC BF17_23400 ENOG4105KUZ arsenate reductase BF17_23445 ENOG4107EG0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity) BF17_23455 ENOG4105RH4 Glycine cleavage system transcriptional repressor BF17_23460 ENOG4108YXY alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen BF17_23480 ENOG4105C02 permease BF17_23495 ENOG4105K89 arsenate reductase BF17_23505 ENOG4105C2W permease BF17_23525 ENOG4108V3E phosphoribosylglycinamide formyltransferase