locus-tag	class	description
FFE93_000005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FFE93_000010	COG0592	DNA-directed DNA polymerase activity
FFE93_000020	COG0187	DNA topoisomerase II activity
FFE93_000025	COG0561	phosphatase activity
FFE93_000035	COG0751	glycine-tRNA ligase activity
FFE93_000045	COG2818	Glycosylase
FFE93_000050	COG0456	acetyltransferase
FFE93_000060	COG2885	chlorophyll binding
FFE93_000080	COG0366	Alpha amylase catalytic
FFE93_000085	COG3977	Valine--pyruvate aminotransferase
FFE93_000090	COG0569	domain protein
FFE93_000090	COG2985	domain, Protein
FFE93_000105	COG5645	(Lipo)protein
FFE93_000110	COG0823	Involved in the tonB-independent uptake of proteins
FFE93_000120	COG3727	T/G mismatch-specific endonuclease activity
FFE93_000140	COG2423	ornithine cyclodeaminase activity
FFE93_000145	COG2213	PTS system mannitol-specific
FFE93_000145	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_000150	COG0246	Mannitol dehydrogenase
FFE93_000155	COG3722	fumarate hydratase activity
FFE93_000165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE93_000180	COG3077	Addiction module antitoxin, RelB DinJ family
FFE93_000185	COG2258	MOSC domain
FFE93_000190	COG0840	transmembrane signaling receptor activity
FFE93_000200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FFE93_000205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FFE93_000215	COG0437	4 iron, 4 sulfur cluster binding
FFE93_000220	COG2864	formate dehydrogenase
FFE93_000230	COG1921	L-seryl-tRNASec selenium transferase activity
FFE93_000235	COG3276	selenocysteine insertion sequence binding
FFE93_000240	COG3622	Belongs to the hyi family
FFE93_000255	COG3274	enterobacterial common antigen metabolic process
FFE93_000270	COG1070	Carbohydrate kinase
FFE93_000275	COG2115	Belongs to the xylose isomerase family
FFE93_000280	COG4213	ABC transporter substrate-binding protein
FFE93_000290	COG4214	carbohydrate transport
FFE93_000295	COG2207	Transcriptional regulator
FFE93_000295	COG1609	Transcriptional regulator
FFE93_000310	COG1393	Belongs to the ArsC family
FFE93_000335	COG1561	YicC-like family, N-terminal region
FFE93_000340	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FFE93_000345	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FFE93_000350	COG1301	dicarboxylic acid transport
FFE93_000355	COG0612	Peptidase, M16
FFE93_000360	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE93_000365	COG1942	4-Oxalocrotonate Tautomerase
FFE93_000370	COG2200	EAL domain
FFE93_000375	COG2982	Protein involved in outer membrane biogenesis
FFE93_000380	COG2134	cdp-diacylglycerol pyrophosphatase
FFE93_000385	COG1295	ribonuclease BN
FFE93_000395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE93_000400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FFE93_000410	COG0742	ribosomal rna small subunit methyltransferase
FFE93_000430	COG0583	DNA-binding transcription factor activity
FFE93_000465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFE93_000480	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FFE93_000485	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFE93_000510	COG2814	Major facilitator Superfamily
FFE93_000525	COG0589	response to stress
FFE93_000535	COG0306	phosphate transporter
FFE93_000540	COG2081	HI0933 family
FFE93_000565	COG3121	Chaperone
FFE93_000585	COG1247	-acetyltransferase
FFE93_000590	COG1741	Belongs to the pirin family
FFE93_000595	COG1609	Transcriptional regulator
FFE93_000600	COG2610	gluconate transmembrane transporter activity
FFE93_000605	COG3265	gluconokinase activity
FFE93_000610	COG2095	MarC family integral membrane protein
FFE93_000615	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FFE93_000620	COG3275	phosphorelay sensor kinase activity
FFE93_000625	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FFE93_000630	COG1523	belongs to the glycosyl hydrolase 13 family
FFE93_000640	COG0297	glycogen (starch) synthase activity
FFE93_000645	COG0058	SHG alpha-glucan phosphorylase activity
FFE93_000650	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FFE93_000655	COG1349	DNA-binding transcription factor activity
FFE93_000660	COG0705	Rhomboid family
FFE93_000680	COG2909	trisaccharide binding
FFE93_000685	COG0058	SHG alpha-glucan phosphorylase activity
FFE93_000690	COG1640	4-alpha-glucanotransferase
FFE93_000695	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FFE93_000695	COG0316	Belongs to the HesB IscA family
FFE93_000700	COG1040	competence protein
FFE93_000705	COG0596	Alpha beta hydrolase
FFE93_000715	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FFE93_000720	COG1918	ferrous iron import across plasma membrane
FFE93_000725	COG2183	response to ionizing radiation
FFE93_000735	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFE93_000740	COG0745	RESPONSE REGULATOR receiver
FFE93_000755	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FFE93_000765	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FFE93_000770	COG1011	Hydrolase
FFE93_000780	COG0494	nUDIX hydrolase
FFE93_000785	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FFE93_000810	COG4796	Type ii and iii secretion system protein
FFE93_000815	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FFE93_000835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FFE93_000845	COG0180	Tryptophanyl-tRNA synthetase
FFE93_000850	COG1648	precorrin-2 dehydrogenase activity
FFE93_000850	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FFE93_000860	COG2146	nitrite reductase [NAD(P)H] activity
FFE93_000865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFE93_000870	COG0402	S-adenosylhomocysteine deaminase activity
FFE93_000875	COG0738	Major facilitator superfamily
FFE93_000895	COG1486	melibiose metabolic process
FFE93_000900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FFE93_000905	COG0433	COG0433 Predicted ATPase
FFE93_000920	COG1289	transmembrane transporter activity
FFE93_000930	COG1765	OsmC-like protein
FFE93_000935	COG3954	Phosphoribulokinase
FFE93_000940	COG3089	Belongs to the UPF0270 family
FFE93_000945	COG0429	hydrolase of the alpha beta-hydrolase fold
FFE93_000960	COG4521	taurine ABC transporter
FFE93_000970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FFE93_000975	COG2175	clavaminate synthase activity
FFE93_000980	COG1216	Glycosyl transferase, family 2
FFE93_000985	COG0488	(ABC) transporter
FFE93_000990	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFE93_001000	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FFE93_001005	COG1047	Peptidyl-prolyl cis-trans
FFE93_001015	COG0545	Peptidyl-prolyl cis-trans isomerase
FFE93_001020	COG2964	Protein conserved in bacteria
FFE93_001025	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FFE93_001035	COG2168	tRNA wobble position uridine thiolation
FFE93_001040	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FFE93_001045	COG0049	tRNA binding
FFE93_001055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FFE93_001075	COG0051	transcription antitermination factor activity, RNA binding
FFE93_001080	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FFE93_001090	COG0089	rRNA binding
FFE93_001095	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FFE93_001100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FFE93_001105	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FFE93_001110	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FFE93_001115	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FFE93_001120	COG0255	Belongs to the universal ribosomal protein uL29 family
FFE93_001125	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FFE93_001130	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FFE93_001145	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FFE93_001155	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FFE93_001160	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FFE93_001165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FFE93_001170	COG1841	ribosomal large subunit assembly
FFE93_001175	COG0200	Binds to the 23S rRNA
FFE93_001180	COG0201	protein transport
FFE93_001185	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FFE93_001190	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FFE93_001195	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FFE93_001200	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FFE93_001210	COG0203	ribosomal protein L17
FFE93_001220	COG0789	Transcriptional regulator
FFE93_001225	COG3036	rescue of stalled ribosome
FFE93_001230	COG1970	mechanosensitive ion channel activity
FFE93_001235	COG0569	domain protein
FFE93_001240	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FFE93_001240	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FFE93_001245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FFE93_001250	COG0242	peptide deformylase activity
FFE93_001255	COG0758	DNA mediated transformation
FFE93_001265	COG0551	DNA topoisomerase type I activity
FFE93_001270	COG0009	L-threonylcarbamoyladenylate synthase
FFE93_001275	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FFE93_001280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FFE93_001325	COG1072	(Pantothenic acid kinase))
FFE93_001370	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFE93_001375	COG0250	Participates in transcription elongation, termination and antitermination
FFE93_001380	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FFE93_001385	COG0081	regulation of translation
FFE93_001390	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FFE93_001395	COG0222	ribosome binding
FFE93_001400	COG0085	RNA polymerase activity
FFE93_001405	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FFE93_001410	COG0823	Involved in the tonB-independent uptake of proteins
FFE93_001425	COG2022	thiamine diphosphate biosynthetic process
FFE93_001430	COG2104	thiamine diphosphate biosynthetic process
FFE93_001435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FFE93_001445	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FFE93_001450	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
FFE93_001455	COG2816	NAD+ diphosphatase activity
FFE93_001465	COG1515	deoxyribonuclease V activity
FFE93_001470	COG3068	Protein conserved in bacteria
FFE93_001485	COG0151	Belongs to the GarS family
FFE93_001535	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FFE93_001540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FFE93_001550	COG2224	Isocitrate lyase
FFE93_001555	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
FFE93_001560	COG1414	Transcriptional regulator
FFE93_001580	COG0527	aspartate kinase activity
FFE93_001585	COG0166	Belongs to the GPI family
FFE93_001590	COG3223	Belongs to the PsiE family
FFE93_001595	COG3833	ABC-type maltose transport systems, permease component
FFE93_001600	COG1175	transmembrane transport
FFE93_001630	COG3161	chorismate lyase activity
FFE93_001640	COG2937	Belongs to the GPAT DAPAT family
FFE93_001645	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FFE93_001650	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FFE93_001655	COG3237	CsbD-like
FFE93_001660	COG0735	belongs to the Fur family
FFE93_001665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFE93_001680	COG0604	alcohol dehydrogenase
FFE93_001685	COG0305	Participates in initiation and elongation during chromosome replication
FFE93_001690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFE93_001695	COG1448	Aminotransferase
FFE93_001700	COG2315	Protein conserved in bacteria
FFE93_001705	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FFE93_001730	COG2252	PERMEase
FFE93_001735	COG0025	NhaP-type Na H and K H
FFE93_001750	COG1126	abc transporter atp-binding protein
FFE93_001755	COG0765	amino acid transport
FFE93_001760	COG4597	amino acid ABC transporter
FFE93_001765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_001770	COG1560	Kdo2-lipid A biosynthetic process
FFE93_001780	COG1129	ABC transporter
FFE93_001785	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_001795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFE93_001805	COG0471	metal ion transport
FFE93_001810	COG1278	Cold shock
FFE93_001815	COG1278	Cold shock
FFE93_001820	COG3133	Outer membrane lipoprotein
FFE93_001825	COG3706	GGDEF domain
FFE93_001830	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FFE93_001835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFE93_001840	COG2264	protein methyltransferase activity
FFE93_001845	COG4145	pantothenate transmembrane transporter activity
FFE93_001850	COG3924	membrane
FFE93_001855	COG0439	Biotin carboxylase
FFE93_001860	COG0511	ligase activity, forming carbon-carbon bonds
FFE93_001865	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FFE93_001870	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FFE93_001880	COG0604	alcohol dehydrogenase
FFE93_001885	COG2199	diguanylate cyclase activity
FFE93_001885	COG2200	EAL domain
FFE93_001890	COG1077	Cell shape determining protein MreB Mrl
FFE93_001895	COG1792	Involved in formation and maintenance of cell shape
FFE93_001900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FFE93_001910	COG1530	ribonuclease E activity
FFE93_001915	COG3164	Protein of unknown function
FFE93_001920	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFE93_001925	COG0312	modulator of DNA gyrase
FFE93_001930	COG0583	DNA-binding transcription factor activity
FFE93_001940	COG1566	PFAM secretion protein HlyD family protein
FFE93_001945	COG1289	transmembrane transporter activity
FFE93_001950	COG1012	belongs to the aldehyde dehydrogenase family
FFE93_001960	COG2732	(Barnase) inhibitor
FFE93_001965	COG3028	Belongs to the UPF0307 family
FFE93_001970	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FFE93_002040	COG4695	Portal protein
FFE93_002200	COG3344	reverse transcriptase
FFE93_002210	COG0312	modulator of DNA gyrase
FFE93_002215	COG3783	Cytochrome b(562)
FFE93_002220	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFE93_002250	COG3964	amidohydrolase
FFE93_002265	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_002265	COG3711	transcriptional antiterminator
FFE93_002270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FFE93_002280	COG1263	PTS System
FFE93_002280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_002285	COG0366	Alpha amylase catalytic
FFE93_002305	COG2308	Evidence 4 Homologs of previously reported genes of
FFE93_002315	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
FFE93_002320	COG0540	Belongs to the ATCase OTCase family
FFE93_002325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_002335	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_002345	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FFE93_002350	COG1137	ATPase activity
FFE93_002355	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FFE93_002360	COG3117	lipopolysaccharide transmembrane transporter activity
FFE93_002365	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FFE93_002370	COG0517	IMP dehydrogenase activity
FFE93_002370	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FFE93_002375	COG0530	calcium, potassium:sodium antiporter activity
FFE93_002380	COG1127	ABC transporter
FFE93_002385	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FFE93_002390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FFE93_002395	COG2854	intermembrane phospholipid transfer
FFE93_002400	COG3113	response to antibiotic
FFE93_002405	COG5007	Belongs to the BolA IbaG family
FFE93_002415	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFE93_002420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFE93_002425	COG3105	Protein conserved in bacteria
FFE93_002430	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FFE93_002435	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FFE93_002440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FFE93_002450	COG0625	glutathione transferase activity
FFE93_002455	COG2969	positive regulation of protein catabolic process
FFE93_002470	COG0493	'glutamate synthase
FFE93_002475	COG0067	glutamate synthase
FFE93_002475	COG0069	glutamate synthase activity
FFE93_002475	COG0070	glutamate synthase
FFE93_002480	COG1242	4 iron, 4 sulfur cluster binding
FFE93_002485	COG5002	protein histidine kinase activity
FFE93_002485	COG0784	Response regulator, receiver
FFE93_002485	COG2198	Histidine kinase
FFE93_002495	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
FFE93_002500	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FFE93_002505	COG2823	Periplasmic or secreted lipoprotein
FFE93_002510	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FFE93_002515	COG0792	nuclease activity
FFE93_002525	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FFE93_002565	COG1064	alcohol dehydrogenase
FFE93_002570	COG1741	Belongs to the pirin family
FFE93_002575	COG0583	DNA-binding transcription factor activity
FFE93_002580	COG0435	Glutathione S-transferase
FFE93_002585	COG2259	Doxx family
FFE93_002595	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
FFE93_002600	COG4575	ribosome binding
FFE93_002615	COG0586	Pfam SNARE associated Golgi protein
FFE93_002630	COG2271	Major facilitator Superfamily
FFE93_002635	COG1904	glucuronate isomerase
FFE93_002640	COG0246	Mannitol dehydrogenase
FFE93_002645	COG2721	sulfolactate sulfo-lyase activity
FFE93_002655	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
FFE93_002660	COG0861	Integral membrane protein TerC family
FFE93_002665	COG0673	inositol 2-dehydrogenase activity
FFE93_002670	COG1451	nucleotide metabolic process
FFE93_002680	COG2813	Specifically methylates the guanine in position
FFE93_002690	COG1902	pentaerythritol trinitrate reductase activity
FFE93_002690	COG0446	pyridine nucleotide-disulphide oxidoreductase
FFE93_002695	COG3247	response to pH
FFE93_002730	COG1815	bacterial-type flagellum-dependent cell motility
FFE93_002735	COG1558	bacterial-type flagellum-dependent cell motility
FFE93_002740	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FFE93_002745	COG1749	Flagellar hook protein flgE
FFE93_002755	COG4786	Flagellar basal body rod
FFE93_002770	COG1705	Flagellar rod assembly protein muramidase FlgJ
FFE93_002770	COG3951	Flagellar rod assembly protein muramidase FlgJ
FFE93_002775	COG1256	bacterial-type flagellum assembly
FFE93_002780	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFE93_002785	COG0840	transmembrane signaling receptor activity
FFE93_002790	COG1191	sigma factor activity
FFE93_002815	COG0643	Histidine kinase
FFE93_002815	COG2198	Histidine kinase
FFE93_002820	COG0835	chemotaxis
FFE93_002825	COG0840	transmembrane signaling receptor activity
FFE93_002860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFE93_002875	COG0745	RESPONSE REGULATOR receiver
FFE93_002880	COG2201	protein-glutamate methylesterase activity
FFE93_002885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FFE93_002890	COG1677	Flagellar hook-basal body complex protein FliE
FFE93_002895	COG1766	The M ring may be actively involved in energy transduction
FFE93_002900	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFE93_002910	COG1157	protein secretion by the type III secretion system
FFE93_002915	COG2882	bacterial-type flagellum organization
FFE93_002925	COG1580	Controls the rotational direction of flagella during chemotaxis
FFE93_002940	COG3190	flagellar
FFE93_002950	COG1987	bacterial-type flagellum assembly
FFE93_002960	COG2197	response regulator
FFE93_002965	COG0840	transmembrane signaling receptor activity
FFE93_002975	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFE93_002980	COG0358	DNA primase activity
FFE93_002990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FFE93_002995	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FFE93_003000	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FFE93_003005	COG1968	undecaprenyl-diphosphatase activity
FFE93_003010	COG0617	tRNA 3'-terminal CCA addition
FFE93_003015	COG4991	sh3 domain protein
FFE93_003020	COG3025	triphosphatase activity
FFE93_003025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FFE93_003030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FFE93_003030	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FFE93_003035	COG0531	amino acid
FFE93_003045	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFE93_003050	COG3384	dioxygenase
FFE93_003055	COG0754	glutathionylspermidine amidase activity
FFE93_003060	COG5463	Belongs to the UPF0441 family
FFE93_003065	COG1538	Outer membrane efflux protein
FFE93_003070	COG0494	nUDIX hydrolase
FFE93_003075	COG3151	Protein conserved in bacteria
FFE93_003080	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FFE93_003085	COG3150	esterase
FFE93_003090	COG0187	DNA topoisomerase II activity
FFE93_003095	COG0583	DNA-binding transcription factor activity
FFE93_003100	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FFE93_003105	COG2249	NAD(P)H dehydrogenase (quinone) activity
FFE93_003120	COG0204	Acyl-transferase
FFE93_003125	COG2132	Multicopper oxidase
FFE93_003135	COG0656	L-ascorbic acid biosynthetic process
FFE93_003140	COG1979	alcohol dehydrogenase
FFE93_003145	COG2207	Transcriptional regulator
FFE93_003150	COG0586	Pfam SNARE associated Golgi protein
FFE93_003160	COG0811	peptide transport
FFE93_003165	COG0848	biopolymer transport protein
FFE93_003215	COG4964	Belongs to the GSP D family
FFE93_003240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE93_003245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_003270	COG1120	ATPase activity
FFE93_003275	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE93_003280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE93_003285	COG4592	Periplasmic binding protein
FFE93_003290	COG1595	DNA-templated transcription, initiation
FFE93_003295	COG3712	iron ion homeostasis
FFE93_003300	COG4771	TonB-dependent receptor
FFE93_003305	COG0612	Peptidase, M16
FFE93_003310	COG4178	(ABC) transporter
FFE93_003315	COG0840	transmembrane signaling receptor activity
FFE93_003335	COG3133	Outer membrane lipoprotein
FFE93_003340	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
FFE93_003345	COG0437	4 iron, 4 sulfur cluster binding
FFE93_003350	COG5557	Pfam Polysulphide reductase, NrfD
FFE93_003355	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FFE93_003360	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FFE93_003365	COG1773	rubredoxin
FFE93_003370	COG0375	protein maturation
FFE93_003375	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FFE93_003380	COG0298	carbon dioxide binding
FFE93_003385	COG0409	Hydrogenase expression formation protein
FFE93_003390	COG0309	Hydrogenase expression formation protein (HypE)
FFE93_003395	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FFE93_003400	COG5001	Diguanylate cyclase
FFE93_003410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_003420	COG0477	Major facilitator Superfamily
FFE93_003430	COG1283	sodium-dependent phosphate transmembrane transporter activity
FFE93_003440	COG1609	Transcriptional regulator
FFE93_003450	COG4607	ABC-type enterochelin transport system periplasmic component
FFE93_003460	COG4605	iron ion homeostasis
FFE93_003465	COG4604	ABC transporter, ATP-binding protein
FFE93_003470	COG0024	Methionine aminopeptidase
FFE93_003480	COG2831	hemolysin activation secretion protein
FFE93_003565	COG1289	transmembrane transporter activity
FFE93_003575	COG0288	reversible hydration of carbon dioxide
FFE93_003665	COG1360	Flagellar Motor Protein
FFE93_003700	COG3501	Rhs element vgr protein
FFE93_003725	COG2771	luxR family
FFE93_003735	COG0583	DNA-binding transcription factor activity
FFE93_003745	COG2373	Large extracellular alpha-helical protein
FFE93_003745	COG1388	LysM domain
FFE93_003745	COG4932	domain protein
FFE93_003775	COG0582	viral genome integration into host DNA
FFE93_003810	COG3539	Fimbrial protein
FFE93_003825	COG0583	DNA-binding transcription factor activity
FFE93_003880	COG1982	Orn Lys Arg decarboxylase major
FFE93_003890	COG0741	lytic transglycosylase activity
FFE93_003900	COG1194	a g-specific adenine glycosylase
FFE93_003905	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FFE93_003910	COG3171	Protein conserved in bacteria
FFE93_003965	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FFE93_004005	COG2184	nucleotidyltransferase activity
FFE93_004075	COG4695	Portal protein
FFE93_004140	COG4974	Belongs to the 'phage' integrase family
FFE93_004145	COG2066	Belongs to the glutaminase family
FFE93_004155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFE93_004160	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FFE93_004165	COG1872	DUF167
FFE93_004170	COG0762	integral membrane protein
FFE93_004175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FFE93_004180	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FFE93_004185	COG2805	Type II/IV secretion system protein
FFE93_004195	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFE93_004200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FFE93_004205	COG1678	Uncharacterized ACR, COG1678
FFE93_004210	COG0189	ligase activity
FFE93_004215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FFE93_004220	COG2356	endonuclease I
FFE93_004225	COG3091	SprT-like family
FFE93_004235	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FFE93_004240	COG1166	arginine decarboxylase activity
FFE93_004250	COG0501	Belongs to the peptidase M48B family
FFE93_004255	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FFE93_004265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FFE93_004270	COG0126	phosphoglycerate kinase activity
FFE93_004275	COG0191	fructose-bisphosphate aldolase activity
FFE93_004280	COG3344	reverse transcriptase
FFE93_004290	COG1279	arginine transmembrane transporter activity
FFE93_004300	COG0583	DNA-binding transcription factor activity
FFE93_004305	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FFE93_004310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFE93_004315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FFE93_004325	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
FFE93_004330	COG3079	Belongs to the UPF0149 family
FFE93_004335	COG0006	proline dipeptidase activity
FFE93_004340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFE93_004345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFE93_004350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FFE93_004360	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FFE93_004360	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FFE93_004365	COG1272	protein, Hemolysin III
FFE93_004370	COG0354	folic acid binding
FFE93_004375	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FFE93_004385	COG0745	RESPONSE REGULATOR receiver
FFE93_004390	COG2205	protein histidine kinase activity
FFE93_004395	COG4452	Inner membrane protein CreD
FFE93_004400	COG0716	FMN binding
FFE93_004405	COG4974	Belongs to the 'phage' integrase family
FFE93_004410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FFE93_004415	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FFE93_004425	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FFE93_004455	COG1215	transferase activity, transferring glycosyl groups
FFE93_004455	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
FFE93_004480	COG3706	GGDEF domain
FFE93_004485	COG1522	sequence-specific DNA binding
FFE93_004500	COG2271	Major facilitator Superfamily
FFE93_004510	COG0484	heat shock protein binding
FFE93_004520	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_004525	COG1733	regulation of RNA biosynthetic process
FFE93_004565	COG4795	General secretion pathway protein
FFE93_004615	COG0583	DNA-binding transcription factor activity
FFE93_004620	COG2814	Major facilitator Superfamily
FFE93_004625	COG0583	DNA-binding transcription factor activity
FFE93_004630	COG0019	diaminopimelate decarboxylase activity
FFE93_004635	COG1609	Transcriptional regulator
FFE93_004645	COG0204	Acyl-transferase
FFE93_004645	COG0318	PFAM AMP-dependent synthetase and ligase
FFE93_004650	COG0477	Major facilitator Superfamily
FFE93_004660	COG0667	Aldo Keto reductase
FFE93_004665	COG0861	Integral membrane protein TerC family
FFE93_004680	COG1051	belongs to the nudix hydrolase family
FFE93_004690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FFE93_004720	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FFE93_004725	COG1025	Belongs to the peptidase M16 family
FFE93_004730	COG1074	ATP-dependent DNA helicase activity
FFE93_004735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FFE93_004740	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FFE93_004740	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FFE93_004745	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFE93_004765	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
FFE93_004770	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FFE93_004775	COG2166	iron-sulfur cluster assembly
FFE93_004780	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FFE93_004790	COG0583	DNA-binding transcription factor activity
FFE93_004795	COG2363	Small membrane protein
FFE93_004800	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
FFE93_004810	COG1611	Belongs to the LOG family
FFE93_004815	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FFE93_004815	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FFE93_004825	COG3098	single-species biofilm formation
FFE93_004830	COG0564	pseudouridine synthase activity
FFE93_004850	COG2171	N-acyltransferase activity
FFE93_004855	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FFE93_004860	COG0024	Methionine aminopeptidase
FFE93_004865	COG0052	Belongs to the universal ribosomal protein uS2 family
FFE93_004870	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FFE93_004875	COG0528	UMP kinase activity
FFE93_004880	COG0233	cytoplasmic translational termination
FFE93_004885	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FFE93_004890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FFE93_004895	COG0575	Belongs to the CDS family
FFE93_004900	COG0750	zinc metalloprotease
FFE93_004910	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
FFE93_004925	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FFE93_004930	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FFE93_004935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FFE93_004940	COG0587	DNA-directed DNA polymerase activity
FFE93_004945	COG0825	malonyl-CoA metabolic process
FFE93_004950	COG0346	lactoylglutathione lyase activity
FFE93_004955	COG0037	tRNA processing
FFE93_004965	COG4568	rho-dependent transcription termination
FFE93_004975	COG4681	YaeQ
FFE93_004985	COG3015	lipoprotein NlpE involved in copper resistance
FFE93_004995	COG1720	tRNA m6t6A37 methyltransferase activity
FFE93_005005	COG1464	Belongs to the NlpA lipoprotein family
FFE93_005010	COG2011	ABC-type metal ion transport system permease component
FFE93_005020	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FFE93_005050	COG0656	L-ascorbic acid biosynthetic process
FFE93_005060	COG3021	interspecies interaction between organisms
FFE93_005065	COG1388	LysM domain
FFE93_005065	COG0741	lytic transglycosylase activity
FFE93_005070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE93_005075	COG2226	methyltransferase
FFE93_005080	COG0328	RNA-DNA hybrid ribonuclease activity
FFE93_005085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FFE93_005095	COG2113	Glycine betaine
FFE93_005100	COG4176	ABC-type proline glycine betaine transport system permease component
FFE93_005105	COG4175	Glycine betaine
FFE93_005110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFE93_005120	COG1780	Probably involved in ribonucleotide reductase function
FFE93_005125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FFE93_005130	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFE93_005140	COG4575	ribosome binding
FFE93_005165	COG1278	Cold shock
FFE93_005175	COG0601	transmembrane transport
FFE93_005180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE93_005205	COG0832	Belongs to the urease beta subunit family
FFE93_005210	COG0804	urea catabolic process
FFE93_005225	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FFE93_005235	COG4413	Urea transporter
FFE93_005240	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
FFE93_005250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FFE93_005255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FFE93_005265	COG2133	pyrroloquinoline quinone binding
FFE93_005270	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE93_005275	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE93_005280	COG2723	6-phospho-beta-galactosidase activity
FFE93_005285	COG1447	Phosphotransferase system cellobiose-specific component IIA
FFE93_005290	COG2169	Transcriptional regulator
FFE93_005290	COG1917	Cupin 2, conserved barrel domain protein
FFE93_005295	COG3394	polysaccharide catabolic process
FFE93_005305	COG3344	reverse transcriptase
FFE93_005390	COG0582	viral genome integration into host DNA
FFE93_005400	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FFE93_005405	COG2867	negative regulation of translational initiation
FFE93_005415	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFE93_005420	COG0497	DNA recombination
FFE93_005425	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FFE93_005430	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FFE93_005435	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
FFE93_005440	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
FFE93_005445	COG0513	Belongs to the DEAD box helicase family
FFE93_005450	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
FFE93_005455	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FFE93_005465	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
FFE93_005475	COG3086	response to oxidative stress
FFE93_005485	COG0481	GTPase activity
FFE93_005490	COG0681	Belongs to the peptidase S26 family
FFE93_005500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FFE93_005505	COG1381	Involved in DNA repair and RecF pathway recombination
FFE93_005510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FFE93_005520	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_005525	COG1737	Transcriptional regulator
FFE93_005535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_005535	COG1263	PTS System
FFE93_005540	COG0560	Phosphoserine phosphatase
FFE93_005550	COG0590	tRNA wobble adenosine to inosine editing
FFE93_005555	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FFE93_005570	COG2205	protein histidine kinase activity
FFE93_005575	COG3170	Tfp pilus assembly protein FimV
FFE93_005580	COG2204	response regulator
FFE93_005585	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FFE93_005585	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FFE93_005590	COG0347	Belongs to the P(II) protein family
FFE93_005605	COG1735	metal-dependent hydrolase with the TIM-barrel fold
FFE93_005610	COG3457	Alanine racemase
FFE93_005620	COG2188	Transcriptional regulator
FFE93_005625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFE93_005625	COG1017	nitric oxide dioxygenase activity
FFE93_005635	COG2814	Major facilitator Superfamily
FFE93_005640	COG3711	transcriptional antiterminator
FFE93_005645	COG3683	transport system, periplasmic component
FFE93_005650	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FFE93_005655	COG0483	inositol monophosphate 1-phosphatase activity
FFE93_005660	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
FFE93_005675	COG0822	iron-sulfur transferase activity
FFE93_005690	COG0443	Heat shock 70 kDa protein
FFE93_005695	COG0633	Ferredoxin
FFE93_005700	COG2975	iron-sulfur cluster assembly
FFE93_005715	COG3468	outer membrane autotransporter barrel domain protein
FFE93_005720	COG2373	Large extracellular alpha-helical protein
FFE93_005725	COG4953	penicillin-binding protein 1C
FFE93_005765	COG2976	Protein conserved in bacteria
FFE93_005770	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFE93_005775	COG1160	GTP binding
FFE93_005785	COG1645	bacterial-type flagellum-dependent swarming motility
FFE93_005790	COG1570	exodeoxyribonuclease VII activity
FFE93_005795	COG0516	GMP reductase activity
FFE93_005795	COG0517	IMP dehydrogenase activity
FFE93_005800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FFE93_005800	COG0519	Catalyzes the synthesis of GMP from XMP
FFE93_005810	COG0351	phosphomethylpyrimidine kinase
FFE93_005825	COG0517	IMP dehydrogenase activity
FFE93_005825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FFE93_005830	COG1349	DNA-binding transcription factor activity
FFE93_005835	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_005840	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_005855	COG3730	PTS system glucitol sorbitol-specific
FFE93_005860	COG1597	lipid kinase activity
FFE93_005870	COG3422	double-strand break repair
FFE93_005875	COG0745	RESPONSE REGULATOR receiver
FFE93_005880	COG2205	protein histidine kinase activity
FFE93_005885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE93_005895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_005900	COG0443	Heat shock 70 kDa protein
FFE93_005905	COG3447	MASE1 domain protein
FFE93_005905	COG5002	protein histidine kinase activity
FFE93_005905	COG5001	Diguanylate cyclase
FFE93_005910	COG2239	Acts as a magnesium transporter
FFE93_005920	COG0248	Ppx GppA phosphatase
FFE93_005925	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FFE93_005930	COG0573	inorganic phosphate transmembrane transporter activity
FFE93_005935	COG0581	inorganic phosphate transmembrane transporter activity
FFE93_005955	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE93_005960	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FFE93_005975	COG2233	PERMEase
FFE93_005980	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FFE93_005985	COG1393	Belongs to the ArsC family
FFE93_005990	COG4783	chaperone-mediated protein folding
FFE93_005995	COG0628	permease
FFE93_006000	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FFE93_006005	COG2716	regulation of RNA biosynthetic process
FFE93_006010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFE93_006015	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FFE93_006020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FFE93_006025	COG2321	neutral zinc metallopeptidase
FFE93_006030	COG2707	UPF0756 membrane protein
FFE93_006035	COG1444	tRNA N-acetyltransferase activity
FFE93_006040	COG0400	carboxylic ester hydrolase activity
FFE93_006050	COG1876	peptidase activity
FFE93_006055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFE93_006060	COG1393	Belongs to the ArsC family
FFE93_006075	COG1175	transmembrane transport
FFE93_006080	COG3842	ATPase activity
FFE93_006090	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE93_006100	COG2197	response regulator
FFE93_006105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_006105	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_006110	COG3062	negative regulation of establishment of protein localization
FFE93_006115	COG0243	molybdopterin cofactor binding
FFE93_006120	COG3043	anaerobic respiration
FFE93_006125	COG3005	denitrification pathway
FFE93_006150	COG1671	Belongs to the UPF0178 family
FFE93_006155	COG0408	coproporphyrinogen oxidase activity
FFE93_006160	COG0456	acetyltransferase
FFE93_006170	COG3111	PFAM Bacterial OB fold (BOF) protein
FFE93_006180	COG2837	iron assimilation
FFE93_006185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FFE93_006200	COG2731	YhcH YjgK YiaL family protein
FFE93_006205	COG1737	Transcriptional regulator
FFE93_006220	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FFE93_006225	COG4208	sulfate ABC transporter
FFE93_006245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_006250	COG0745	RESPONSE REGULATOR receiver
FFE93_006255	COG2205	protein histidine kinase activity
FFE93_006260	COG2190	(PTS) system
FFE93_006270	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_006275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FFE93_006330	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
FFE93_006340	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FFE93_006345	COG3530	Putative quorum-sensing-regulated virulence factor
FFE93_006375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFE93_006405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FFE93_006410	COG1914	H( )-stimulated, divalent metal cation uptake system
FFE93_006420	COG0667	Aldo Keto reductase
FFE93_006435	COG0837	glucose binding
FFE93_006440	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FFE93_006450	COG2223	nitrite transmembrane transporter activity
FFE93_006455	COG3279	Response regulator of the LytR AlgR family
FFE93_006460	COG3275	phosphorelay sensor kinase activity
FFE93_006475	COG0436	Aminotransferase
FFE93_006480	COG3038	cytochrome b561
FFE93_006490	COG1598	PFAM Uncharacterised protein family UPF0150
FFE93_006530	COG2951	lytic endotransglycosylase activity
FFE93_006535	COG0531	amino acid
FFE93_006555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FFE93_006560	COG1127	ABC transporter
FFE93_006575	COG3038	cytochrome b561
FFE93_006580	COG2353	YceI-like domain
FFE93_006585	COG1609	Transcriptional regulator
FFE93_006590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_006590	COG1263	PTS System
FFE93_006595	COG2723	6-phospho-beta-galactosidase activity
FFE93_006605	COG1695	Transcriptional regulator
FFE93_006610	COG2824	Alkylphosphonate utilization operon protein PhnA
FFE93_006625	COG2116	formate transmembrane transporter activity
FFE93_006635	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFE93_006640	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFE93_006645	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FFE93_006650	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FFE93_006655	COG1138	Cytochrome C-type biogenesis protein
FFE93_006660	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE93_006665	COG4235	cytochrome complex assembly
FFE93_006665	COG3088	subunit of a heme lyase
FFE93_006670	COG3088	subunit of a heme lyase
FFE93_006670	COG4235	cytochrome complex assembly
FFE93_006685	COG3691	Protein conserved in bacteria
FFE93_006690	COG0183	Belongs to the thiolase family
FFE93_006695	COG1250	3-hydroxyacyl-CoA dehydrogenase
FFE93_006695	COG1024	Enoyl-CoA hydratase
FFE93_006700	COG2062	phosphohistidine phosphatase, SixA
FFE93_006710	COG2840	Smr protein MutS2
FFE93_006715	COG2890	protein-(glutamine-N5) methyltransferase activity
FFE93_006725	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FFE93_006730	COG0730	response to heat
FFE93_006735	COG3101	peptidyl-lysine hydroxylation
FFE93_006745	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FFE93_006745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FFE93_006750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFE93_006755	COG0745	RESPONSE REGULATOR receiver
FFE93_006755	COG3706	GGDEF domain
FFE93_006760	COG1794	racemase activity, acting on amino acids and derivatives
FFE93_006785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE93_006790	COG0697	spore germination
FFE93_006815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FFE93_006825	COG0586	Pfam SNARE associated Golgi protein
FFE93_006835	COG0285	dihydrofolate synthase activity
FFE93_006840	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
FFE93_006845	COG1286	toxin biosynthetic process
FFE93_006850	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FFE93_006855	COG0163	prenyltransferase activity
FFE93_006860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_006865	COG4215	(ABC) transporter
FFE93_006870	COG4160	amino acid transport
FFE93_006885	COG1090	epimerase
FFE93_006895	COG0622	Phosphoesterase
FFE93_006900	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
FFE93_006905	COG0561	phosphatase activity
FFE93_006910	COG2706	6-phosphogluconolactonase activity
FFE93_006920	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FFE93_006925	COG0156	8-amino-7-oxononanoate synthase activity
FFE93_006930	COG2226	methyltransferase
FFE93_006935	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FFE93_006945	COG0556	nucleotide-excision repair
FFE93_006950	COG4628	conserved protein (DUF2132)
FFE93_006955	COG0391	Required for morphogenesis under gluconeogenic growth conditions
FFE93_006960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FFE93_006965	COG0315	cyclic pyranopterin monophosphate synthase activity
FFE93_006970	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FFE93_006975	COG0314	molybdopterin synthase activity
FFE93_006980	COG0670	Belongs to the BI1 family
FFE93_006985	COG0842	Transport permease protein
FFE93_006990	COG0842	Transport permease protein
FFE93_006995	COG1131	(ABC) transporter
FFE93_007000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_007005	COG1309	transcriptional regulator
FFE93_007010	COG0513	Belongs to the DEAD box helicase family
FFE93_007015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FFE93_007030	COG1686	Belongs to the peptidase S11 family
FFE93_007035	COG0277	FAD linked oxidase domain protein
FFE93_007045	COG1403	HNH endonuclease
FFE93_007055	COG2261	transglycosylase associated protein
FFE93_007065	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FFE93_007080	COG4807	Protein conserved in bacteria
FFE93_007100	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FFE93_007110	COG2897	thiosulfate sulfurtransferase activity
FFE93_007160	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FFE93_007180	COG0681	Belongs to the peptidase S26 family
FFE93_007200	COG1802	Transcriptional regulator
FFE93_007200	COG4626	Terminase
FFE93_007205	COG4725	Belongs to the MT-A70-like family
FFE93_007215	COG3646	Phage regulatory protein
FFE93_007215	COG3645	SOS response
FFE93_007220	COG1403	HNH endonuclease
FFE93_007240	COG3772	lysozyme
FFE93_007265	COG4626	Terminase
FFE93_007265	COG1802	Transcriptional regulator
FFE93_007275	COG4695	Portal protein
FFE93_007320	COG4386	tail sheath protein
FFE93_007370	COG3299	homolog of phage Mu protein gp47
FFE93_007375	COG3778	Protein conserved in bacteria
FFE93_007405	COG3082	Protein of unknown function (DUF1414)
FFE93_007410	COG3081	Nucleoid-associated protein
FFE93_007420	COG1061	Type III restriction enzyme res subunit
FFE93_007425	COG1187	pseudouridine synthase activity
FFE93_007430	COG2814	Major facilitator Superfamily
FFE93_007440	COG4172	Belongs to the ABC transporter superfamily
FFE93_007445	COG4239	(ABC) transporter, permease
FFE93_007450	COG4174	ABC transporter (Permease)
FFE93_007455	COG4166	transmembrane transport
FFE93_007460	COG2200	EAL domain
FFE93_007465	COG0791	NLP P60 protein
FFE93_007470	COG0671	phosphoesterase, PA-phosphatase related
FFE93_007475	COG0523	cobalamin synthesis protein
FFE93_007485	COG2186	Transcriptional regulator
FFE93_007490	COG0246	Mannitol dehydrogenase
FFE93_007500	COG1312	Catalyzes the dehydration of D-mannonate
FFE93_007505	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FFE93_007520	COG0243	molybdopterin cofactor binding
FFE93_007525	COG3005	denitrification pathway
FFE93_007540	COG1105	Belongs to the carbohydrate kinase PfkB family
FFE93_007545	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFE93_007545	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FFE93_007545	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FFE93_007550	COG3344	reverse transcriptase
FFE93_007555	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
FFE93_007560	COG2855	membrane
FFE93_007570	COG0583	DNA-binding transcription factor activity
FFE93_007575	COG0833	amino acid
FFE93_007590	COG4771	TonB-dependent receptor
FFE93_007595	COG0625	glutathione transferase activity
FFE93_007620	COG2011	ABC-type metal ion transport system permease component
FFE93_007635	COG0626	cystathionine gamma-synthase activity
FFE93_007645	COG1686	Belongs to the peptidase S11 family
FFE93_007650	COG1760	l-serine dehydratase
FFE93_007655	COG0814	amino acid
FFE93_007660	COG1349	DNA-binding transcription factor activity
FFE93_007665	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FFE93_007670	COG0671	phosphoesterase, PA-phosphatase related
FFE93_007750	COG4695	Portal protein
FFE93_007775	COG0569	domain protein
FFE93_007775	COG2985	domain, Protein
FFE93_007780	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FFE93_007800	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FFE93_007805	COG3842	ATPase activity
FFE93_007810	COG1176	ABC-type spermidine putrescine transport system, permease component I
FFE93_007815	COG1177	transmembrane transport
FFE93_007830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_007835	COG4160	amino acid transport
FFE93_007840	COG4215	(ABC) transporter
FFE93_007845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_007850	COG1126	abc transporter atp-binding protein
FFE93_007855	COG1605	Chorismate mutase
FFE93_007865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE93_007870	COG0702	epimerase
FFE93_007875	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
FFE93_007880	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FFE93_007885	COG0028	Belongs to the TPP enzyme family
FFE93_007890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFE93_007895	COG1151	hydroxylamine reductase activity
FFE93_007900	COG2431	L-lysine efflux transmembrane transporter activity
FFE93_007905	COG3593	DNA synthesis involved in DNA repair
FFE93_007910	COG2990	Protein conserved in bacteria
FFE93_007915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_007925	COG1278	Cold shock
FFE93_007930	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FFE93_007935	COG0542	response to heat
FFE93_007940	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FFE93_007945	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FFE93_007950	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FFE93_007960	COG0492	ferredoxin-NADP+ reductase activity
FFE93_007970	COG3107	peptidoglycan biosynthetic process
FFE93_007970	COG1674	ftsk spoiiie
FFE93_007975	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FFE93_007980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FFE93_007985	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FFE93_007990	COG2814	Major facilitator Superfamily
FFE93_007995	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FFE93_008000	COG1882	Formate acetyltransferase
FFE93_008005	COG2116	formate transmembrane transporter activity
FFE93_008010	COG1944	ATP diphosphatase activity
FFE93_008015	COG0252	asparaginase activity
FFE93_008020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FFE93_008025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FFE93_008035	COG0539	negative regulation of cytoplasmic translation
FFE93_008040	COG0776	regulation of translation
FFE93_008045	COG2333	competence protein COMEC
FFE93_008045	COG0658	competence protein
FFE93_008060	COG5383	Protein conserved in bacteria
FFE93_008070	COG1278	Cold shock
FFE93_008075	COG2835	tetraacyldisaccharide 4'-kinase activity
FFE93_008085	COG3173	Aminoglycoside phosphotransferase
FFE93_008090	COG1434	Gram-negative-bacterium-type cell wall biogenesis
FFE93_008095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FFE93_008100	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
FFE93_008105	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
FFE93_008115	COG2989	Protein conserved in bacteria
FFE93_008120	COG3108	Peptidase M15
FFE93_008125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FFE93_008130	COG2200	EAL domain
FFE93_008135	COG1448	Aminotransferase
FFE93_008145	COG0017	Asparaginyl-tRNA synthetase
FFE93_008150	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
FFE93_008155	COG0308	aminopeptidase N
FFE93_008160	COG0167	dihydroorotate dehydrogenase activity
FFE93_008170	COG0633	Ferredoxin
FFE93_008170	COG3217	Mosc domain protein beta barrel domain protein
FFE93_008175	COG0116	Belongs to the methyltransferase superfamily
FFE93_008175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FFE93_008180	COG0488	(ABC) transporter
FFE93_008185	COG2995	paraquat-inducible protein a
FFE93_008190	COG3008	intermembrane lipid transfer
FFE93_008190	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FFE93_008195	COG3009	Protein conserved in bacteria
FFE93_008200	COG3130	regulation of translation
FFE93_008205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFE93_008215	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FFE93_008220	COG1067	ATP-dependent peptidase activity
FFE93_008225	COG3120	sequence-specific DNA binding
FFE93_008230	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FFE93_008230	COG2885	chlorophyll binding
FFE93_008235	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
FFE93_008240	COG3070	regulator of competence-specific genes
FFE93_008245	COG1289	transmembrane transporter activity
FFE93_008250	COG3304	Inner membrane component domain
FFE93_008255	COG0210	DNA helicase
FFE93_008265	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FFE93_008270	COG1832	CoA-binding protein
FFE93_008275	COG3785	DNA binding
FFE93_008285	COG1254	Belongs to the acylphosphatase family
FFE93_008290	COG2920	part of a sulfur-relay system
FFE93_008315	COG0463	Glycosyl transferase, family 2
FFE93_008345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FFE93_008350	COG0543	2 iron, 2 sulfur cluster binding
FFE93_008350	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFE93_008390	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
FFE93_008395	COG0437	4 iron, 4 sulfur cluster binding
FFE93_008400	COG3301	Polysulphide reductase, NrfD
FFE93_008405	COG1138	Cytochrome C-type biogenesis protein
FFE93_008410	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FFE93_008415	COG3088	subunit of a heme lyase
FFE93_008420	COG4235	cytochrome complex assembly
FFE93_008425	COG2771	luxR family
FFE93_008430	COG3916	Acyl-homoserine-lactone synthase
FFE93_008440	COG3263	regulation of cellular component size
FFE93_008455	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FFE93_008460	COG2943	transferase activity, transferring hexosyl groups
FFE93_008465	COG5645	(Lipo)protein
FFE93_008475	COG3104	oligopeptide transport
FFE93_008480	COG2259	Doxx family
FFE93_008485	COG1560	Kdo2-lipid A biosynthetic process
FFE93_008525	COG0628	permease
FFE93_008555	COG0418	dihydroorotase activity
FFE93_008560	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FFE93_008565	COG1530	ribonuclease E activity
FFE93_008570	COG0564	pseudouridine synthase activity
FFE93_008580	COG1399	metal-binding, possibly nucleic acid-binding protein
FFE93_008585	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FFE93_008590	COG0416	fatty acid biosynthetic process
FFE93_008600	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FFE93_008605	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_008615	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FFE93_008620	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFE93_008625	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FFE93_008630	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FFE93_008635	COG0470	DNA polymerase III
FFE93_008640	COG0084	hydrolase, TatD family'
FFE93_008645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_008645	COG1263	PTS System
FFE93_008665	COG0641	radical SAM
FFE93_008675	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FFE93_008680	COG0537	adenosine 5'-monophosphoramidase activity
FFE93_008685	COG5633	Lipoprotein
FFE93_008690	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
FFE93_008705	COG3150	esterase
FFE93_008710	COG1252	NADH dehydrogenase
FFE93_008715	COG3134	Outer membrane lipoprotein
FFE93_008720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FFE93_008725	COG4591	ABC-type transport system involved in lipoprotein release permease component
FFE93_008735	COG4591	ABC-type transport system involved in lipoprotein release permease component
FFE93_008740	COG1940	carbohydrate kinase activity
FFE93_008745	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FFE93_008760	COG2850	peptidyl-arginine hydroxylation
FFE93_008770	COG0745	RESPONSE REGULATOR receiver
FFE93_008775	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FFE93_008780	COG2915	High frequency lysogenization protein hflD homolog
FFE93_008785	COG0482	sulfurtransferase activity
FFE93_008795	COG1187	pseudouridine synthase activity
FFE93_008800	COG0538	isocitrate dehydrogenase activity
FFE93_008810	COG0561	phosphatase activity
FFE93_008825	COG3493	citrate carrier protein
FFE93_008830	COG4565	transcriptional regulatory protein
FFE93_008835	COG3290	protein histidine kinase activity
FFE93_008840	COG2066	Belongs to the glutaminase family
FFE93_008850	COG1609	Transcriptional regulator
FFE93_008855	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE93_008860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
FFE93_008865	COG2723	6-phospho-beta-galactosidase activity
FFE93_008870	COG1447	Phosphotransferase system cellobiose-specific component IIA
FFE93_008880	COG0672	)-iron permease
FFE93_008895	COG1136	(ABC) transporter
FFE93_008895	COG0577	efflux transmembrane transporter activity
FFE93_008905	COG1136	(ABC) transporter
FFE93_008905	COG0577	efflux transmembrane transporter activity
FFE93_008925	COG4114	ferric iron reductase
FFE93_008930	COG0006	proline dipeptidase activity
FFE93_008935	COG0457	Tetratricopeptide repeat
FFE93_008940	COG1649	PFAM Uncharacterised BCR, COG1649
FFE93_008940	COG0726	polysaccharide deacetylase
FFE93_008945	COG1215	transferase activity, transferring glycosyl groups
FFE93_008950	COG3658	cytochrome
FFE93_008965	COG1702	phosphate starvation-inducible protein PhoH
FFE93_008970	COG0387	Pfam Sodium calcium exchanger
FFE93_008985	COG0583	DNA-binding transcription factor activity
FFE93_008990	COG3850	Histidine kinase
FFE93_009000	COG1294	oxidase, subunit
FFE93_009005	COG1271	oxidase subunit
FFE93_009010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE93_009015	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FFE93_009020	COG3138	arginine N-succinyltransferase
FFE93_009030	COG3724	N-succinylarginine dihydrolase activity
FFE93_009035	COG2988	succinylglutamate desuccinylase activity
FFE93_009050	COG1228	amidohydrolase
FFE93_009060	COG0402	S-adenosylhomocysteine deaminase activity
FFE93_009070	COG3443	Belongs to the bacterial solute-binding protein 9 family
FFE93_009080	COG4942	peptidase
FFE93_009085	COG0667	Aldo Keto reductase
FFE93_009090	COG0656	L-ascorbic acid biosynthetic process
FFE93_009120	COG1073	alpha beta
FFE93_009130	COG0012	GTP binding
FFE93_009140	COG0193	aminoacyl-tRNA hydrolase activity
FFE93_009150	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FFE93_009160	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FFE93_009165	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FFE93_009175	COG2890	protein-(glutamine-N5) methyltransferase activity
FFE93_009180	COG3094	Invasion gene expression up-regulator, SirB
FFE93_009185	COG2912	Transglutaminase-like superfamily
FFE93_009195	COG0659	secondary active sulfate transmembrane transporter activity
FFE93_009200	COG3706	GGDEF domain
FFE93_009215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FFE93_009225	COG3381	protein complex oligomerization
FFE93_009235	COG0477	Major facilitator Superfamily
FFE93_009240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE93_009250	COG0673	inositol 2-dehydrogenase activity
FFE93_009265	COG3102	Protein conserved in bacteria
FFE93_009270	COG3142	Participates in the control of copper homeostasis
FFE93_009280	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FFE93_009290	COG3788	relative of glutathione S-transferase, MAPEG superfamily
FFE93_009295	COG1335	isochorismatase
FFE93_009305	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FFE93_009310	COG0494	nUDIX hydrolase
FFE93_009315	COG0217	transcriptional regulatory protein
FFE93_009325	COG0632	four-way junction helicase activity
FFE93_009330	COG2255	four-way junction helicase activity
FFE93_009335	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE93_009340	COG1121	(ABC) transporter
FFE93_009345	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
FFE93_009350	COG0739	heme binding
FFE93_009355	COG1560	Kdo2-lipid A biosynthetic process
FFE93_009360	COG0469	pyruvate kinase activity
FFE93_009365	COG1737	Transcriptional regulator
FFE93_009370	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FFE93_009375	COG0800	Aldolase
FFE93_009380	COG2076	Multidrug Resistance protein
FFE93_009385	COG2076	Multidrug Resistance protein
FFE93_009390	COG0251	oxidation-reduction process
FFE93_009395	COG1199	ATP-dependent helicase activity
FFE93_009405	COG3065	identical protein binding
FFE93_009410	COG0318	PFAM AMP-dependent synthetase and ligase
FFE93_009415	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FFE93_009420	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
FFE93_009425	COG2894	cell division
FFE93_009430	COG0850	regulation of cytokinetic process
FFE93_009440	COG0179	Fumarylacetoacetate (FAA) hydrolase
FFE93_009445	COG2983	Belongs to the UPF0260 family
FFE93_009460	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FFE93_009465	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FFE93_009475	COG2186	Transcriptional regulator
FFE93_009480	COG4139	cobalamin transport
FFE93_009485	COG0386	Belongs to the glutathione peroxidase family
FFE93_009490	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
FFE93_009495	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFE93_009500	COG0463	Glycosyl transferase, family 2
FFE93_009510	COG0726	polysaccharide deacetylase
FFE93_009515	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
FFE93_009520	COG2076	Multidrug Resistance protein
FFE93_009525	COG2076	Multidrug Resistance protein
FFE93_009530	COG0791	NLP P60 protein
FFE93_009535	COG0095	Lipoate-protein ligase
FFE93_009545	COG4771	TonB-dependent receptor
FFE93_009560	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
FFE93_009570	COG0574	Belongs to the PEP-utilizing enzyme family
FFE93_009570	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFE93_009580	COG0628	permease
FFE93_009585	COG0277	FAD linked oxidase domain protein
FFE93_009585	COG0247	lactate metabolic process
FFE93_009590	COG2050	protein possibly involved in aromatic compounds catabolism
FFE93_009600	COG0316	Belongs to the HesB IscA family
FFE93_009605	COG0719	Fe-S assembly protein
FFE93_009610	COG0396	ATPase activity
FFE93_009615	COG0719	Fe-S assembly protein
FFE93_009625	COG2166	iron-sulfur cluster assembly
FFE93_009630	COG1376	ErfK ybiS ycfS ynhG family protein
FFE93_009630	COG1388	LysM domain
FFE93_009635	COG4238	major outer membrane lipoprotein
FFE93_009655	COG0534	Mate efflux family protein
FFE93_009660	COG0307	riboflavin synthase, alpha
FFE93_009665	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FFE93_009670	COG2814	Major facilitator Superfamily
FFE93_009675	COG0583	DNA-binding transcription factor activity
FFE93_009680	COG1609	Transcriptional regulator
FFE93_009690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FFE93_009695	COG0791	NLP P60 protein
FFE93_009700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FFE93_009705	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FFE93_009710	COG0346	lactoylglutathione lyase activity
FFE93_009715	COG1902	pentaerythritol trinitrate reductase activity
FFE93_009720	COG1309	transcriptional regulator
FFE93_009725	COG2194	sulfuric ester hydrolase activity
FFE93_009730	COG3313	Fe-S protein
FFE93_009735	COG4989	oxidoreductase activity
FFE93_009750	COG1846	Transcriptional regulator
FFE93_009755	COG3133	Outer membrane lipoprotein
FFE93_009760	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FFE93_009765	COG3895	Periplasmic Protein
FFE93_009775	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FFE93_009785	COG0625	glutathione transferase activity
FFE93_009805	COG3104	oligopeptide transport
FFE93_009810	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFE93_009810	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FFE93_009820	COG4172	Belongs to the ABC transporter superfamily
FFE93_009830	COG4171	peptide transport system, permease
FFE93_009835	COG4168	peptide transport system, permease
FFE93_009840	COG4166	transmembrane transport
FFE93_009850	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
FFE93_009855	COG1842	Phage shock protein A
FFE93_009865	COG1983	PspC domain protein
FFE93_009875	COG3106	COG3106 Predicted ATPase
FFE93_009880	COG3768	UPF0283 membrane protein
FFE93_009900	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FFE93_009905	COG4948	Mandelate Racemase Muconate Lactonizing
FFE93_009910	COG2866	Carboxypeptidase
FFE93_009915	COG4166	transmembrane transport
FFE93_009935	COG0037	tRNA processing
FFE93_009940	COG3711	transcriptional antiterminator
FFE93_009945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_009945	COG2190	(PTS) system
FFE93_009945	COG1263	PTS System
FFE93_009950	COG2723	6-phospho-beta-galactosidase activity
FFE93_009955	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FFE93_009955	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_009955	COG1013	pyruvate-flavodoxin oxidoreductase activity
FFE93_009955	COG0674	pyruvate-flavodoxin oxidoreductase activity
FFE93_009965	COG1285	pathogenesis
FFE93_009970	COG3042	response to heat
FFE93_009975	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFE93_009980	COG2911	Protein conserved in bacteria
FFE93_009990	COG3784	Protein of unknown function (DUF1318)
FFE93_010010	COG0477	Major facilitator Superfamily
FFE93_010015	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FFE93_010020	COG1643	Atp-dependent helicase
FFE93_010040	COG3591	Belongs to the peptidase S1B family
FFE93_010045	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FFE93_010050	COG2205	protein histidine kinase activity
FFE93_010055	COG0745	RESPONSE REGULATOR receiver
FFE93_010065	COG0531	amino acid
FFE93_010075	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FFE93_010080	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FFE93_010085	COG0589	response to stress
FFE93_010090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FFE93_010095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FFE93_010105	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FFE93_010135	COG1011	Hydrolase
FFE93_010145	COG0531	amino acid
FFE93_010150	COG0076	glutamate decarboxylase activity
FFE93_010155	COG3023	N-Acetylmuramoyl-L-alanine amidase
FFE93_010175	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FFE93_010195	COG4215	(ABC) transporter
FFE93_010205	COG1522	sequence-specific DNA binding
FFE93_010215	COG0625	glutathione transferase activity
FFE93_010235	COG0640	Transcriptional regulator
FFE93_010240	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FFE93_010255	COG4221	oxidoreductase activity
FFE93_010310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
FFE93_010315	COG1940	carbohydrate kinase activity
FFE93_010340	COG0583	DNA-binding transcription factor activity
FFE93_010345	COG2814	Major facilitator Superfamily
FFE93_010365	COG2814	Major facilitator Superfamily
FFE93_010375	COG4644	lycopene metabolic process
FFE93_010385	COG0114	fumarate hydratase activity
FFE93_010390	COG1482	cell wall glycoprotein biosynthetic process
FFE93_010395	COG5339	Protein conserved in bacteria
FFE93_010405	COG1609	Transcriptional regulator
FFE93_010410	COG1263	PTS System
FFE93_010410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_010415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FFE93_010425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FFE93_010430	COG0385	Bile acid
FFE93_010435	COG0673	inositol 2-dehydrogenase activity
FFE93_010445	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_010455	COG1879	ABC-type sugar transport system periplasmic component
FFE93_010470	COG2274	protein secretion by the type I secretion system
FFE93_010480	COG2274	protein secretion by the type I secretion system
FFE93_010485	COG2759	Belongs to the formate--tetrahydrofolate ligase family
FFE93_010495	COG4657	Part of a membrane complex involved in electron transport
FFE93_010505	COG4656	Part of a membrane complex involved in electron transport
FFE93_010510	COG3708	Transcriptional regulator
FFE93_010510	COG2207	Transcriptional regulator
FFE93_010520	COG4659	FMN binding
FFE93_010530	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FFE93_010535	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
FFE93_010540	COG1966	Carbon starvation protein
FFE93_010545	COG2879	small protein
FFE93_010550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FFE93_010555	COG1349	DNA-binding transcription factor activity
FFE93_010560	COG0235	Class ii aldolase
FFE93_010570	COG0023	Translation Initiation Factor
FFE93_010575	COG0284	orotidine-5'-phosphate decarboxylase activity
FFE93_010590	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FFE93_010595	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
FFE93_010600	COG0671	phosphoesterase, PA-phosphatase related
FFE93_010605	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FFE93_010610	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FFE93_010625	COG0583	DNA-binding transcription factor activity
FFE93_010630	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FFE93_010645	COG0616	signal peptide processing
FFE93_010650	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_010665	COG1187	pseudouridine synthase activity
FFE93_010680	COG0009	L-threonylcarbamoyladenylate synthase
FFE93_010685	COG0613	PHP domain protein
FFE93_010700	COG0512	Glutamine amidotransferase of anthranilate synthase
FFE93_010710	COG0134	indole-3-glycerol-phosphate synthase activity
FFE93_010710	COG0135	phosphoribosylanthranilate isomerase activity
FFE93_010715	COG0133	tryptophan synthase activity
FFE93_010730	COG3047	cAMP biosynthetic process
FFE93_010750	COG2917	probably involved in intracellular septation
FFE93_010755	COG1607	acyl-coa hydrolase
FFE93_010760	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
FFE93_010765	COG2350	Protein conserved in bacteria
FFE93_010780	COG2200	EAL domain
FFE93_010790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FFE93_010805	COG0444	Belongs to the ABC transporter superfamily
FFE93_010810	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE93_010830	COG2095	MarC family integral membrane protein
FFE93_010840	COG1454	alcohol dehydrogenase
FFE93_010840	COG1012	belongs to the aldehyde dehydrogenase family
FFE93_010845	COG1435	thymidine kinase activity
FFE93_010855	COG2916	Histone family protein nucleoid-structuring protein H-NS
FFE93_010865	COG0745	RESPONSE REGULATOR receiver
FFE93_010870	COG1752	Esterase of the alpha-beta hydrolase superfamily
FFE93_010880	COG3012	SEC-C Motif Domain Protein
FFE93_010885	COG0788	formyltetrahydrofolate deformylase activity
FFE93_010925	COG0583	DNA-binding transcription factor activity
FFE93_010930	COG0708	Exodeoxyribonuclease III
FFE93_010935	COG0494	nUDIX hydrolase
FFE93_010945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FFE93_010960	COG0778	Nitroreductase
FFE93_010965	COG0616	signal peptide processing
FFE93_010970	COG0252	asparaginase activity
FFE93_010975	COG1335	isochorismatase
FFE93_010980	COG3139	Protein of unknown function (DUF1315)
FFE93_011005	COG3713	MltA-interacting MipA family protein
FFE93_011015	COG2766	serine protein kinase
FFE93_011020	COG2718	Belongs to the UPF0229 family
FFE93_011030	COG0583	DNA-binding transcription factor activity
FFE93_011040	COG2202	Pas domain
FFE93_011040	COG2199	diguanylate cyclase activity
FFE93_011040	COG2200	EAL domain
FFE93_011045	COG2814	Major facilitator Superfamily
FFE93_011050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_011060	COG1538	Outer membrane efflux protein
FFE93_011065	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FFE93_011075	COG2719	SpoVR family
FFE93_011145	COG2314	TM2 domain
FFE93_011150	COG0776	regulation of translation
FFE93_011170	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FFE93_011175	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FFE93_011185	COG4249	Peptidase C14 caspase catalytic subunit p20
FFE93_011190	COG1811	Na channel or pump
FFE93_011225	COG0803	Belongs to the bacterial solute-binding protein 9 family
FFE93_011230	COG1121	(ABC) transporter
FFE93_011235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE93_011240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE93_011260	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFE93_011265	COG1917	Cupin 2, conserved barrel domain protein
FFE93_011270	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_011280	COG1175	transmembrane transport
FFE93_011285	COG0395	ABC-type sugar transport system, permease component
FFE93_011290	COG3842	ATPase activity
FFE93_011300	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FFE93_011305	COG1988	membrane-bound metal-dependent
FFE93_011315	COG3023	N-Acetylmuramoyl-L-alanine amidase
FFE93_011325	COG0823	Involved in the tonB-independent uptake of proteins
FFE93_011330	COG2814	Major facilitator Superfamily
FFE93_011335	COG0501	Belongs to the peptidase M48B family
FFE93_011340	COG0793	Belongs to the peptidase S41A family
FFE93_011350	COG1956	GAF domain-containing protein
FFE93_011355	COG2995	paraquat-inducible protein a
FFE93_011360	COG3008	intermembrane lipid transfer
FFE93_011370	COG2814	Major facilitator Superfamily
FFE93_011405	COG4251	negative regulation of phosphorylation
FFE93_011405	COG5001	Diguanylate cyclase
FFE93_011405	COG3706	GGDEF domain
FFE93_011405	COG2203	Gaf domain
FFE93_011425	COG0625	glutathione transferase activity
FFE93_011445	COG3122	Protein conserved in bacteria
FFE93_011500	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FFE93_011615	COG3566	protein conserved in bacteria
FFE93_011625	COG3567	Phage-associated protein, HI1409 family
FFE93_011635	COG3077	Addiction module antitoxin, RelB DinJ family
FFE93_011640	COG2026	Addiction module toxin, RelE StbE family
FFE93_011660	COG1475	DNA binding
FFE93_011670	COG0515	serine threonine protein kinase
FFE93_011670	COG2815	serine threonine protein kinase
FFE93_011685	COG3772	lysozyme
FFE93_011765	COG1396	sequence-specific DNA binding
FFE93_011805	COG0582	viral genome integration into host DNA
FFE93_011815	COG1276	copper resistance
FFE93_011820	COG2372	response to copper ion
FFE93_011825	COG1528	Iron-storage protein
FFE93_011850	COG1770	oligopeptidase
FFE93_011865	COG3141	response to X-ray
FFE93_011870	COG0513	Belongs to the DEAD box helicase family
FFE93_011875	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
FFE93_011880	COG3140	Belongs to the UPF0181 family
FFE93_011890	COG0494	nUDIX hydrolase
FFE93_011895	COG1760	l-serine dehydratase
FFE93_011900	COG1253	flavin adenine dinucleotide binding
FFE93_011905	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_011905	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_011910	COG3715	PTS system
FFE93_011915	COG3716	PTS system mannose fructose sorbose family IID component
FFE93_011920	COG4811	Protein of unknown function (DUF986)
FFE93_011925	COG1971	Probably functions as a manganese efflux pump
FFE93_011935	COG3447	MASE1 domain protein
FFE93_011935	COG5001	Diguanylate cyclase
FFE93_011935	COG5002	protein histidine kinase activity
FFE93_011945	COG2226	methyltransferase
FFE93_011955	COG3344	reverse transcriptase
FFE93_011960	COG1278	Cold shock
FFE93_011975	COG1113	amino acid transport
FFE93_012010	COG2207	Transcriptional regulator
FFE93_012030	COG1132	(ABC) transporter
FFE93_012050	COG2203	Gaf domain
FFE93_012050	COG4251	negative regulation of phosphorylation
FFE93_012050	COG5001	Diguanylate cyclase
FFE93_012050	COG3706	GGDEF domain
FFE93_012060	COG1733	regulation of RNA biosynthetic process
FFE93_012065	COG0702	epimerase
FFE93_012070	COG0840	transmembrane signaling receptor activity
FFE93_012090	COG4974	Belongs to the 'phage' integrase family
FFE93_012165	COG4695	Portal protein
FFE93_012355	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FFE93_012405	COG1196	nuclear chromosome segregation
FFE93_012405	COG0741	lytic transglycosylase activity
FFE93_012405	COG0739	heme binding
FFE93_012505	COG3772	lysozyme
FFE93_012555	COG0305	Participates in initiation and elongation during chromosome replication
FFE93_012585	COG3344	reverse transcriptase
FFE93_012640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FFE93_012645	COG0322	excinuclease ABC activity
FFE93_012650	COG2197	response regulator
FFE93_012660	COG3136	membrane protein required for alginate biosynthesis
FFE93_012670	COG0840	transmembrane signaling receptor activity
FFE93_012705	COG1113	amino acid transport
FFE93_012710	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
FFE93_012725	COG0477	Major facilitator Superfamily
FFE93_012750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFE93_012755	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FFE93_012755	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FFE93_012755	COG0506	proline dehydrogenase activity
FFE93_012785	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FFE93_012795	COG1191	sigma factor activity
FFE93_012830	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
FFE93_012840	COG1677	Flagellar hook-basal body complex protein FliE
FFE93_012850	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FFE93_012855	COG1317	bacterial-type flagellum organization
FFE93_012865	COG2882	bacterial-type flagellum organization
FFE93_012910	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FFE93_012915	COG1256	bacterial-type flagellum assembly
FFE93_012935	COG4786	Flagellar basal body rod
FFE93_012945	COG1749	Flagellar hook protein flgE
FFE93_012950	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FFE93_012955	COG1558	bacterial-type flagellum-dependent cell motility
FFE93_012960	COG1815	bacterial-type flagellum-dependent cell motility
FFE93_012970	COG2747	anti-sigma28 factor FlgM
FFE93_012975	COG3418	PFAM FlgN family protein
FFE93_012985	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFE93_012990	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FFE93_012995	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FFE93_013000	COG0745	RESPONSE REGULATOR receiver
FFE93_013010	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FFE93_013015	COG0840	transmembrane signaling receptor activity
FFE93_013020	COG0840	transmembrane signaling receptor activity
FFE93_013035	COG0835	chemotaxis
FFE93_013040	COG0643	Histidine kinase
FFE93_013040	COG2198	Histidine kinase
FFE93_013045	COG1360	Flagellar Motor Protein
FFE93_013065	COG0589	response to stress
FFE93_013075	COG1285	pathogenesis
FFE93_013080	COG0840	transmembrane signaling receptor activity
FFE93_013090	COG1278	Cold shock
FFE93_013095	COG1609	Transcriptional regulator
FFE93_013100	COG3250	beta-galactosidase activity
FFE93_013105	COG0604	alcohol dehydrogenase
FFE93_013105	COG3321	synthase
FFE93_013105	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_013135	COG3121	Chaperone
FFE93_013150	COG3228	Belongs to the MtfA family
FFE93_013170	COG0471	metal ion transport
FFE93_013185	COG3051	citrate lyase alpha subunit
FFE93_013190	COG2301	Belongs to the HpcH HpaI aldolase family
FFE93_013195	COG3052	prosthetic group binding
FFE93_013200	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
FFE93_013205	COG3290	protein histidine kinase activity
FFE93_013210	COG4565	transcriptional regulatory protein
FFE93_013225	COG2271	Major facilitator Superfamily
FFE93_013230	COG1840	ABC-type Fe3 transport system, periplasmic component
FFE93_013240	COG3842	ATPase activity
FFE93_013255	COG2205	protein histidine kinase activity
FFE93_013255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_013265	COG3121	Chaperone
FFE93_013270	COG3188	usher protein
FFE93_013280	COG3121	Chaperone
FFE93_013285	COG1187	pseudouridine synthase activity
FFE93_013295	COG0488	(ABC) transporter
FFE93_013300	COG0784	Response regulator, receiver
FFE93_013300	COG0835	chemotaxis
FFE93_013305	COG0534	Mate efflux family protein
FFE93_013310	COG0137	argininosuccinate synthase activity
FFE93_013315	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FFE93_013325	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FFE93_013335	COG1492	cobalamin metabolic process
FFE93_013385	COG2875	Belongs to the precorrin methyltransferase family
FFE93_013395	COG2241	protein methyltransferase activity
FFE93_013400	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FFE93_013410	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
FFE93_013430	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FFE93_013465	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
FFE93_013495	COG1012	belongs to the aldehyde dehydrogenase family
FFE93_013505	COG4656	Part of a membrane complex involved in electron transport
FFE93_013515	COG4810	utilization protein
FFE93_013525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FFE93_013530	COG1648	precorrin-2 dehydrogenase activity
FFE93_013530	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FFE93_013535	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FFE93_013545	COG1879	ABC-type sugar transport system periplasmic component
FFE93_013555	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_013565	COG2926	Belongs to the UPF0265 family
FFE93_013575	COG2925	Exonuclease
FFE93_013580	COG0531	amino acid
FFE93_013590	COG0371	Dehydrogenase
FFE93_013595	COG1129	ABC transporter
FFE93_013600	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_013605	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE93_013615	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FFE93_013620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FFE93_013625	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FFE93_013630	COG0131	Imidazoleglycerol-phosphate dehydratase
FFE93_013630	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FFE93_013635	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FFE93_013640	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FFE93_013645	COG0107	imidazoleglycerol-phosphate synthase activity
FFE93_013650	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FFE93_013650	COG0140	phosphoribosyl-ATP diphosphatase activity
FFE93_013655	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FFE93_013660	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FFE93_013665	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FFE93_013675	COG0438	transferase activity, transferring glycosyl groups
FFE93_013685	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
FFE93_013720	COG1253	flavin adenine dinucleotide binding
FFE93_013725	COG3069	C4-dicarboxylate transmembrane transporter activity
FFE93_013730	COG2982	Protein involved in outer membrane biogenesis
FFE93_013740	COG0572	uridine kinase
FFE93_013745	COG0489	protein tyrosine kinase activity
FFE93_013750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFE93_013750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FFE93_013765	COG2814	Major facilitator Superfamily
FFE93_013770	COG1380	Effector of murein hydrolase LrgA
FFE93_013775	COG1346	cytolysis
FFE93_013785	COG0281	malic enzyme
FFE93_013795	COG2949	membrane
FFE93_013805	COG0298	carbon dioxide binding
FFE93_013810	COG0375	protein maturation
FFE93_013815	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_013820	COG0651	ATP synthesis coupled electron transport
FFE93_013825	COG0650	Formate hydrogenlyase subunit 4
FFE93_013830	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FFE93_013835	COG4237	Hydrogenase 4 membrane
FFE93_013840	COG0651	ATP synthesis coupled electron transport
FFE93_013845	COG3261	NADH dehydrogenase
FFE93_013845	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
FFE93_013850	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_013855	COG3260	NADH ubiquinone oxidoreductase 20
FFE93_013865	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
FFE93_013870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_013875	COG3383	formate dehydrogenase (NAD+) activity
FFE93_013880	COG3604	Transcriptional regulator
FFE93_013905	COG2311	Membrane
FFE93_013910	COG0302	gtp cyclohydrolase
FFE93_013915	COG0477	Major facilitator Superfamily
FFE93_013920	COG0583	DNA-binding transcription factor activity
FFE93_013950	COG1136	(ABC) transporter
FFE93_013965	COG0303	'Molybdopterin
FFE93_013970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FFE93_013975	COG0488	(ABC) transporter
FFE93_013995	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FFE93_014010	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FFE93_014030	COG0783	Belongs to the Dps family
FFE93_014035	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FFE93_014040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_014045	COG0765	amino acid transport
FFE93_014050	COG1126	abc transporter atp-binding protein
FFE93_014055	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
FFE93_014070	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FFE93_014075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FFE93_014095	COG0697	spore germination
FFE93_014105	COG1982	Orn Lys Arg decarboxylase major
FFE93_014110	COG0531	amino acid
FFE93_014115	COG1174	glycine betaine transport
FFE93_014120	COG1125	glycine betaine transport
FFE93_014125	COG1174	glycine betaine transport
FFE93_014130	COG1732	Glycine betaine
FFE93_014135	COG2723	6-phospho-beta-galactosidase activity
FFE93_014140	COG1263	PTS System
FFE93_014140	COG2190	(PTS) system
FFE93_014140	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_014145	COG1737	Transcriptional regulator
FFE93_014180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FFE93_014195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
FFE93_014205	COG2223	nitrite transmembrane transporter activity
FFE93_014210	COG2198	Histidine kinase
FFE93_014210	COG0642	Histidine kinase
FFE93_014220	COG2205	protein histidine kinase activity
FFE93_014220	COG0784	Response regulator, receiver
FFE93_014230	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FFE93_014235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FFE93_014245	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FFE93_014250	COG4574	serine-type endopeptidase inhibitor activity
FFE93_014280	COG0814	amino acid
FFE93_014300	COG1441	menaquinone biosynthetic process
FFE93_014305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
FFE93_014315	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FFE93_014320	COG1169	isochorismate synthase
FFE93_014335	COG4575	ribosome binding
FFE93_014340	COG0129	dihydroxy-acid dehydratase activity
FFE93_014355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FFE93_014360	COG1609	Transcriptional regulator
FFE93_014365	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_014370	COG3265	gluconokinase activity
FFE93_014385	COG1007	ATP synthesis coupled electron transport
FFE93_014390	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_014395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FFE93_014400	COG0713	ATP synthesis coupled electron transport
FFE93_014405	COG0839	Belongs to the complex I subunit 6 family
FFE93_014410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_014415	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FFE93_014420	COG1034	ATP synthesis coupled electron transport
FFE93_014425	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FFE93_014430	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FFE93_014435	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_014435	COG0649	NAD binding
FFE93_014440	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_014445	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FFE93_014450	COG0583	DNA-binding transcription factor activity
FFE93_014455	COG0436	Aminotransferase
FFE93_014460	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FFE93_014470	COG0490	domain, Protein
FFE93_014470	COG0471	metal ion transport
FFE93_014480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFE93_014485	COG3013	Belongs to the UPF0304 family
FFE93_014490	COG3092	negative regulation of chromosome organization
FFE93_014500	COG0280	phosphate acetyltransferase
FFE93_014500	COG0857	belongs to the CobB CobQ family
FFE93_014505	COG1609	Transcriptional regulator
FFE93_014520	COG3037	sugar-specific permease SgaT UlaA
FFE93_014530	COG4149	molybdate abc transporter
FFE93_014535	COG0725	ABC transporter, periplasmic molybdate-binding protein
FFE93_014545	COG3585	molybdate ion transport
FFE93_014545	COG2005	Transcriptional regulator
FFE93_014550	COG1119	ATPase activity
FFE93_014560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FFE93_014565	COG1085	galactose-1-phosphate uridylyltransferase
FFE93_014570	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FFE93_014575	COG2017	converts alpha-aldose to the beta-anomer
FFE93_014585	COG0588	phosphoglycerate mutase activity
FFE93_014590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FFE93_014595	COG1230	cation diffusion facilitator family transporter
FFE93_014605	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FFE93_014635	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FFE93_014640	COG2885	chlorophyll binding
FFE93_014645	COG0823	Involved in the tonB-independent uptake of proteins
FFE93_014650	COG3064	Membrane
FFE93_014650	COG3064	Membrane
FFE93_014655	COG0848	biopolymer transport protein
FFE93_014660	COG0811	peptide transport
FFE93_014665	COG0824	Thioesterase
FFE93_014670	COG3790	cyd operon protein YbgE
FFE93_014675	COG4890	Cyd operon protein YbgT
FFE93_014680	COG1294	oxidase, subunit
FFE93_014685	COG1271	oxidase subunit
FFE93_014690	COG0737	Belongs to the 5'-nucleotidase family
FFE93_014695	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FFE93_014700	COG0045	succinate-CoA ligase (ADP-forming) activity
FFE93_014705	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFE93_014710	COG0567	Dehydrogenase, E1 component
FFE93_014715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FFE93_014720	COG1053	succinate dehydrogenase
FFE93_014725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FFE93_014730	COG2009	succinate dehydrogenase
FFE93_014760	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FFE93_014765	COG1984	allophanate hydrolase subunit 2
FFE93_014770	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
FFE93_014775	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FFE93_014780	COG5212	phosphodiesterase
FFE93_014785	COG0415	Belongs to the DNA photolyase family
FFE93_014790	COG3272	Protein of unknown function (DUF1722)
FFE93_014805	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FFE93_014810	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FFE93_014815	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FFE93_014820	COG2205	protein histidine kinase activity
FFE93_014825	COG0745	RESPONSE REGULATOR receiver
FFE93_014845	COG0033	Phosphoglucomutase
FFE93_014850	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
FFE93_014855	COG0596	Alpha beta hydrolase
FFE93_014865	COG0840	transmembrane signaling receptor activity
FFE93_014875	COG0735	belongs to the Fur family
FFE93_014895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFE93_014900	COG1263	PTS System
FFE93_014900	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FFE93_014900	COG2190	(PTS) system
FFE93_014910	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FFE93_014915	COG1846	Transcriptional regulator
FFE93_014915	COG1940	carbohydrate kinase activity
FFE93_014920	COG0647	UMP catabolic process
FFE93_014925	COG0367	asparagine synthase
FFE93_014960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FFE93_014965	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FFE93_014970	COG1702	phosphate starvation-inducible protein PhoH
FFE93_014975	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FFE93_014980	COG4535	Mg2 and Co2 transporter CorC
FFE93_014985	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FFE93_015005	COG0765	amino acid transport
FFE93_015010	COG0765	amino acid transport
FFE93_015015	COG1126	abc transporter atp-binding protein
FFE93_015020	COG2888	peptidyl-tyrosine sulfation
FFE93_015025	COG0495	leucyl-tRNA aminoacylation
FFE93_015030	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
FFE93_015035	COG1466	dna polymerase III delta subunit
FFE93_015040	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FFE93_015045	COG0799	negative regulation of ribosome biogenesis
FFE93_015055	COG0768	penicillin binding
FFE93_015060	COG0772	Belongs to the SEDS family
FFE93_015065	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FFE93_015070	COG1686	Belongs to the peptidase S11 family
FFE93_015075	COG2921	Belongs to the UPF0250 family
FFE93_015080	COG0321	lipoyl(octanoyl) transferase activity
FFE93_015085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FFE93_015090	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFE93_015095	COG3706	GGDEF domain
FFE93_015100	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FFE93_015105	COG1278	Cold shock
FFE93_015110	COG1278	Cold shock
FFE93_015115	COG2197	response regulator
FFE93_015125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FFE93_015140	COG5265	(ABC) transporter
FFE93_015145	COG2850	peptidyl-arginine hydroxylation
FFE93_015150	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
FFE93_015180	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FFE93_015235	COG4386	tail sheath protein
FFE93_015400	COG0582	viral genome integration into host DNA
FFE93_015410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FFE93_015415	COG2501	S4 domain
FFE93_015420	COG0215	cysteine-tRNA ligase activity
FFE93_015425	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FFE93_015430	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FFE93_015435	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FFE93_015440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FFE93_015445	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FFE93_015450	COG4181	ATPase activity
FFE93_015455	COG2755	lipolytic protein G-D-S-L family
FFE93_015460	COG0300	oxidoreductase activity
FFE93_015465	COG3118	belongs to the thioredoxin family
FFE93_015470	COG0330	HflC and HflK could
FFE93_015475	COG1585	Membrane protein implicated in regulation of membrane protease activity
FFE93_015480	COG0789	Transcriptional regulator
FFE93_015485	COG2217	Heavy metal translocating P-type atpase
FFE93_015490	COG3735	TraB family
FFE93_015495	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FFE93_015515	COG0737	Belongs to the 5'-nucleotidase family
FFE93_015520	COG2223	nitrite transmembrane transporter activity
FFE93_015525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FFE93_015525	COG4651	solute:proton antiporter activity
FFE93_015530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE93_015535	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FFE93_015550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE93_015590	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FFE93_015595	COG0563	adenylate kinase activity
FFE93_015600	COG0326	Molecular chaperone. Has ATPase activity
FFE93_015605	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FFE93_015620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FFE93_015625	COG2832	Protein of unknown function (DUF454)
FFE93_015640	COG1196	nuclear chromosome segregation
FFE93_015640	COG3264	Mechanosensitive ion channel
FFE93_015645	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FFE93_015650	COG1309	transcriptional regulator
FFE93_015655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_015660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE93_015670	COG3457	Alanine racemase
FFE93_015675	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FFE93_015680	COG0254	rRNA binding
FFE93_015685	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FFE93_015690	COG0803	Belongs to the bacterial solute-binding protein 9 family
FFE93_015695	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FFE93_015700	COG1121	(ABC) transporter
FFE93_015725	COG3695	enzyme binding
FFE93_015730	COG3126	Type III secretion system lipoprotein chaperone (YscW)
FFE93_015735	COG1946	Acyl-CoA thioesterase
FFE93_015740	COG0004	ammonium transporteR
FFE93_015745	COG0347	Belongs to the P(II) protein family
FFE93_015750	COG1132	(ABC) transporter
FFE93_015755	COG1132	(ABC) transporter
FFE93_015760	COG1522	sequence-specific DNA binding
FFE93_015770	COG0561	phosphatase activity
FFE93_015775	COG4533	DNA binding
FFE93_015780	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FFE93_015785	COG0824	Thioesterase
FFE93_015790	COG1555	photosystem II stabilization
FFE93_015795	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFE93_015800	COG0776	regulation of translation
FFE93_015805	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FFE93_015810	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FFE93_015815	COG0740	serine-type endopeptidase activity
FFE93_015820	COG0544	peptidyl-prolyl cis-trans isomerase activity
FFE93_015830	COG0271	Belongs to the BolA IbaG family
FFE93_015835	COG3056	Lipoprotein
FFE93_015840	COG2223	nitrite transmembrane transporter activity
FFE93_015850	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FFE93_015855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FFE93_015860	COG1845	cytochrome c oxidase, subunit III
FFE93_015865	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FFE93_015870	COG0109	protoheme IX farnesyltransferase activity
FFE93_015875	COG2814	Major facilitator Superfamily
FFE93_015880	COG1666	GTP binding
FFE93_015885	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FFE93_015890	COG0693	protein deglycase activity
FFE93_015895	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFE93_015895	COG0301	tRNA thio-modification
FFE93_015900	COG1722	exodeoxyribonuclease VII activity
FFE93_015905	COG0142	geranyltranstransferase activity
FFE93_015910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FFE93_015915	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FFE93_015920	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FFE93_015930	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FFE93_015935	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FFE93_015935	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FFE93_015940	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FFE93_015950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFE93_015955	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FFE93_015960	COG1862	Preprotein translocase
FFE93_015965	COG0343	queuine tRNA-ribosyltransferase activity
FFE93_015970	COG0546	phosphoglycolate phosphatase activity
FFE93_015970	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FFE93_016265	COG0582	viral genome integration into host DNA
FFE93_016270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FFE93_016275	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
FFE93_016280	COG0450	alkyl hydroperoxide reductase
FFE93_016300	COG0366	Alpha amylase catalytic
FFE93_016310	COG1114	Component of the transport system for branched-chain amino acids
FFE93_016320	COG5002	protein histidine kinase activity
FFE93_016325	COG0745	RESPONSE REGULATOR receiver
FFE93_016330	COG0420	3'-5' exonuclease activity
FFE93_016335	COG0419	ATPase involved in DNA repair
FFE93_016340	COG1940	carbohydrate kinase activity
FFE93_016345	COG2974	May be involved in recombination
FFE93_016350	COG3123	guanosine phosphorylase activity
FFE93_016355	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FFE93_016400	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FFE93_016405	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FFE93_016425	COG2195	Cleaves the N-terminal amino acid of tripeptides
FFE93_016430	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FFE93_016440	COG2991	Protein conserved in bacteria
FFE93_016445	COG1477	protein flavinylation
FFE93_016450	COG2871	sodium ion transport
FFE93_016455	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FFE93_016460	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FFE93_016465	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FFE93_016470	COG1805	sodium ion transport
FFE93_016475	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
FFE93_016480	COG3034	peptidoglycan biosynthetic process
FFE93_016485	COG0121	glutamine amidotransferase
FFE93_016495	COG1960	acyl-CoA dehydrogenase activity
FFE93_016500	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
FFE93_016510	COG2831	hemolysin activation secretion protein
FFE93_016515	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
FFE93_016525	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
FFE93_016535	COG0235	Class ii aldolase
FFE93_016540	COG0436	Aminotransferase
FFE93_016550	COG2814	Major facilitator Superfamily
FFE93_016555	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FFE93_016565	COG1846	Transcriptional regulator
FFE93_016570	COG1566	PFAM secretion protein HlyD family protein
FFE93_016575	COG2814	Major facilitator Superfamily
FFE93_016580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFE93_016585	COG3118	belongs to the thioredoxin family
FFE93_016595	COG0045	succinate-CoA ligase (ADP-forming) activity
FFE93_016595	COG1042	CoA-binding domain protein
FFE93_016595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FFE93_016600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FFE93_016640	COG0542	response to heat
FFE93_016650	COG0564	pseudouridine synthase activity
FFE93_016660	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FFE93_016665	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FFE93_016670	COG0077	Prephenate dehydratase
FFE93_016670	COG1605	Chorismate mutase
FFE93_016675	COG1605	Chorismate mutase
FFE93_016675	COG0287	Prephenate dehydrogenase
FFE93_016680	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FFE93_016685	COG3279	Response regulator of the LytR AlgR family
FFE93_016690	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FFE93_016695	COG3137	Salt-induced outer membrane protein
FFE93_016700	COG0335	large ribosomal subunit rRNA binding
FFE93_016710	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FFE93_016720	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FFE93_016725	COG4137	Cytochrome C assembly protein
FFE93_016730	COG4536	flavin adenine dinucleotide binding
FFE93_016735	COG1854	S-ribosylhomocysteine lyase activity
FFE93_016740	COG2918	glutathione biosynthetic process
FFE93_016745	COG1238	metal cluster binding
FFE93_016750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFE93_016785	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FFE93_016790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FFE93_016795	COG2137	regulation of response to DNA damage stimulus
FFE93_016800	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FFE93_016825	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFE93_016830	COG3958	Transketolase
FFE93_016835	COG3959	Transketolase, thiamine diphosphate binding domain
FFE93_016840	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_016845	COG1129	ABC transporter
FFE93_016855	COG1609	Transcriptional regulator
FFE93_016870	COG3381	protein complex oligomerization
FFE93_016875	COG3302	dmso reductase anchor subunit
FFE93_016880	COG0437	4 iron, 4 sulfur cluster binding
FFE93_016885	COG0243	molybdopterin cofactor binding
FFE93_016890	COG1454	alcohol dehydrogenase
FFE93_016895	COG0235	Class ii aldolase
FFE93_016900	COG0738	Major facilitator superfamily
FFE93_016910	COG1070	Carbohydrate kinase
FFE93_016920	COG1349	DNA-binding transcription factor activity
FFE93_016925	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FFE93_016925	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FFE93_016930	COG0640	Transcriptional regulator
FFE93_016935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FFE93_016950	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FFE93_016955	COG4598	ABC transporter
FFE93_016965	COG0765	amino acid transport
FFE93_016980	COG0444	Belongs to the ABC transporter superfamily
FFE93_016990	COG0601	transmembrane transport
FFE93_016995	COG0747	negative chemotaxis
FFE93_017000	COG4948	Mandelate Racemase Muconate Lactonizing
FFE93_017005	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_017025	COG1538	Outer membrane efflux protein
FFE93_017030	COG0577	efflux transmembrane transporter activity
FFE93_017030	COG1136	(ABC) transporter
FFE93_017035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_017070	COG3539	Fimbrial protein
FFE93_017080	COG3121	Chaperone
FFE93_017085	COG3188	usher protein
FFE93_017110	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FFE93_017115	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FFE93_017120	COG1388	LysM domain
FFE93_017120	COG4942	peptidase
FFE93_017125	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FFE93_017130	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FFE93_017135	COG0585	pseudouridine synthase activity
FFE93_017140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FFE93_017150	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FFE93_017155	COG2390	Transcriptional regulator
FFE93_017160	COG1461	Dihydroxyacetone kinase
FFE93_017165	COG2376	Dihydroxyacetone kinase
FFE93_017170	COG1028	Short-chain dehydrogenase reductase Sdr
FFE93_017175	COG2814	Major facilitator Superfamily
FFE93_017180	COG1063	alcohol dehydrogenase
FFE93_017185	COG0698	ribose 5-phosphate isomerase
FFE93_017195	COG0529	Catalyzes the synthesis of activated sulfate
FFE93_017200	COG2895	sulfate adenylyltransferase (ATP) activity
FFE93_017205	COG0175	sulfate reduction
FFE93_017210	COG1648	precorrin-2 dehydrogenase activity
FFE93_017210	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FFE93_017215	COG2234	aminopeptidase activity
FFE93_017220	COG0175	sulfate reduction
FFE93_017225	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FFE93_017230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FFE93_017235	COG0720	synthase
FFE93_017240	COG0602	queuosine metabolic process
FFE93_017255	COG0148	phosphopyruvate hydratase activity
FFE93_017260	COG0504	CTP synthase activity
FFE93_017265	COG3956	TIGRFAM MazG family protein
FFE93_017270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FFE93_017275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FFE93_017285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FFE93_017290	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FFE93_017295	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FFE93_017305	COG2860	membrane
FFE93_017315	COG0316	Belongs to the HesB IscA family
FFE93_017325	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FFE93_017335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE93_017340	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FFE93_017345	COG1120	ATPase activity
FFE93_017350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FFE93_017355	COG1643	Atp-dependent helicase
FFE93_017360	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FFE93_017365	COG1489	DNA binding
FFE93_017370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FFE93_017375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FFE93_017380	COG0617	tRNA 3'-terminal CCA addition
FFE93_017385	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FFE93_017390	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FFE93_017395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FFE93_017400	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FFE93_017405	COG0726	polysaccharide deacetylase
FFE93_017410	COG0842	Transport permease protein
FFE93_017415	COG1131	(ABC) transporter
FFE93_017420	COG0288	reversible hydration of carbon dioxide
FFE93_017425	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FFE93_017430	COG2132	Multicopper oxidase
FFE93_017440	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FFE93_017505	COG3112	Uncharacterised protein family (UPF0231)
FFE93_017520	COG2207	Transcriptional regulator
FFE93_017525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE93_017530	COG0508	dehydrogenase complex catalyzes the overall conversion of
FFE93_017535	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
FFE93_017545	COG2186	Transcriptional regulator
FFE93_017550	COG1113	amino acid transport
FFE93_017555	COG3725	Membrane protein required for beta-lactamase induction
FFE93_017560	COG3023	N-Acetylmuramoyl-L-alanine amidase
FFE93_017570	COG4969	Belongs to the N-Me-Phe pilin family
FFE93_017575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FFE93_017580	COG1459	type II secretion system
FFE93_017585	COG0516	GMP reductase activity
FFE93_017595	COG0237	dephospho-CoA kinase activity
FFE93_017605	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FFE93_017610	COG0494	nUDIX hydrolase
FFE93_017635	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FFE93_017640	COG0849	cell division
FFE93_017645	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FFE93_017655	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FFE93_017660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FFE93_017665	COG0772	Belongs to the SEDS family
FFE93_017675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFE93_017680	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FFE93_017685	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FFE93_017690	COG0768	penicillin binding
FFE93_017695	COG3116	cell division
FFE93_017700	COG0275	rRNA processing
FFE93_017715	COG1609	Transcriptional regulator
FFE93_017725	COG0028	Belongs to the TPP enzyme family
FFE93_017730	COG1022	Amp-dependent synthetase and ligase
FFE93_017750	COG0473	3-isopropylmalate dehydrogenase activity
FFE93_017755	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FFE93_017765	COG2814	Major facilitator Superfamily
FFE93_017775	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FFE93_017780	COG4533	DNA binding
FFE93_017785	COG4143	(ABC) transporter
FFE93_017790	COG1178	ABC-type Fe3 transport system permease component
FFE93_017800	COG0586	Pfam SNARE associated Golgi protein
FFE93_017805	COG0417	DNA replication proofreading
FFE93_017815	COG0564	pseudouridine synthase activity
FFE93_017825	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FFE93_017830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FFE93_017835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFE93_017845	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FFE93_017850	COG2967	ApaG domain
FFE93_017855	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FFE93_017860	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FFE93_017870	COG2966	Psort location CytoplasmicMembrane, score
FFE93_017875	COG1280	lysine exporter protein (LysE YggA)
FFE93_017880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FFE93_017885	COG0505	Belongs to the CarA family
FFE93_017890	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FFE93_017895	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FFE93_017900	COG1047	Peptidyl-prolyl cis-trans
FFE93_017905	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FFE93_017910	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FFE93_017915	COG0196	riboflavin kinase activity
FFE93_017935	COG0583	DNA-binding transcription factor activity
FFE93_017940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FFE93_017945	COG0484	heat shock protein binding
FFE93_017955	COG1584	GPR1 FUN34 yaaH family protein
FFE93_017965	COG0477	Major facilitator Superfamily
FFE93_017970	COG0521	Mo-molybdopterin cofactor biosynthetic process
FFE93_017975	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FFE93_017985	COG3022	response to hydroperoxide
FFE93_017995	COG0083	homoserine kinase activity
FFE93_018010	COG0745	RESPONSE REGULATOR receiver
FFE93_018015	COG3045	CreA protein
FFE93_018020	COG2207	Transcriptional regulator
FFE93_018020	COG3708	Transcriptional regulator
FFE93_018030	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
FFE93_018035	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
FFE93_018040	COG0741	lytic transglycosylase activity
FFE93_018045	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FFE93_018055	COG2199	diguanylate cyclase activity
FFE93_018060	COG2885	chlorophyll binding
FFE93_018065	COG0488	(ABC) transporter
FFE93_018075	COG0583	DNA-binding transcription factor activity
FFE93_018080	COG0604	alcohol dehydrogenase
FFE93_018095	COG0560	Phosphoserine phosphatase
FFE93_018100	COG3726	membrane protein affecting hemolysin expression
FFE93_018105	COG3550	peptidyl-serine autophosphorylation
FFE93_018115	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FFE93_018120	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FFE93_018125	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
FFE93_018130	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FFE93_018135	COG0084	hydrolase, TatD family'
FFE93_018140	COG4667	esterase of the alpha-beta hydrolase superfamily
FFE93_018150	COG2823	Periplasmic or secreted lipoprotein
FFE93_018155	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FFE93_018165	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
FFE93_018185	COG0667	Aldo Keto reductase
FFE93_018215	COG3706	GGDEF domain
FFE93_018250	COG3284	Transcriptional regulator
FFE93_018275	COG2192	nodulation
FFE93_018285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FFE93_018285	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
FFE93_018285	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FFE93_018290	COG1461	Dihydroxyacetone kinase
FFE93_018295	COG2376	Dihydroxyacetone kinase
FFE93_018305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FFE93_018310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FFE93_018320	COG2235	arginine
FFE93_018335	COG0859	PFAM glycosyl transferase family 9
FFE93_018340	COG1070	Carbohydrate kinase
FFE93_018345	COG2390	Transcriptional regulator
FFE93_018355	COG1129	ABC transporter
FFE93_018360	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_018365	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_018370	COG1879	ABC-type sugar transport system periplasmic component
FFE93_018375	COG1830	Aldolase
FFE93_018410	COG1401	restriction endodeoxyribonuclease activity
FFE93_018520	COG4619	ABC transporter
FFE93_018540	COG0582	viral genome integration into host DNA
FFE93_018550	COG0795	lipopolysaccharide-transporting ATPase activity
FFE93_018555	COG0795	lipopolysaccharide-transporting ATPase activity
FFE93_018560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FFE93_018565	COG2927	DNA polymerase III (CHI subunit)
FFE93_018580	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
FFE93_018590	COG2731	YhcH YjgK YiaL family protein
FFE93_018600	COG0601	transmembrane transport
FFE93_018605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE93_018610	COG0444	Belongs to the ABC transporter superfamily
FFE93_018615	COG4608	Belongs to the ABC transporter superfamily
FFE93_018625	COG0602	queuosine metabolic process
FFE93_018640	COG2188	Transcriptional regulator
FFE93_018645	COG3624	Phosphonate C-P lyase system protein PhnG
FFE93_018650	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FFE93_018655	COG3626	phosphonate metabolism
FFE93_018660	COG3627	carbon phosphorus lyase activity
FFE93_018665	COG4107	phosphonate C-P lyase system protein PhnK
FFE93_018670	COG4778	phosphonate C-P lyase system protein PhnL
FFE93_018675	COG3454	Phosphonate metabolism
FFE93_018680	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FFE93_018685	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FFE93_018690	COG0702	epimerase
FFE93_018695	COG3787	Belongs to the UPF0306 family
FFE93_018705	COG3842	ATPase activity
FFE93_018710	COG0395	ABC-type sugar transport system, permease component
FFE93_018720	COG1653	transport
FFE93_018740	COG1982	Orn Lys Arg decarboxylase major
FFE93_018745	COG0531	amino acid
FFE93_018750	COG2827	Endonuclease containing a URI domain
FFE93_018755	COG3153	acetyltransferase
FFE93_018775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FFE93_018780	COG0513	Belongs to the DEAD box helicase family
FFE93_018795	COG1185	polyribonucleotide nucleotidyltransferase activity
FFE93_018805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FFE93_018810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FFE93_018820	COG0195	Participates in both transcription termination and antitermination
FFE93_018840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FFE93_018850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FFE93_018855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FFE93_018860	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FFE93_018865	COG1534	Rna-binding protein
FFE93_018870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FFE93_018875	COG2027	D-alanyl-D-alanine carboxypeptidase
FFE93_018880	COG0745	RESPONSE REGULATOR receiver
FFE93_018885	COG0642	Histidine kinase
FFE93_018890	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FFE93_018895	COG0697	spore germination
FFE93_018910	COG0142	geranyltranstransferase activity
FFE93_018920	COG3423	Transcriptional regulator
FFE93_018940	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FFE93_018945	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FFE93_018955	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FFE93_018960	COG2105	PFAM AIG2 family protein
FFE93_018965	COG2911	Protein conserved in bacteria
FFE93_018975	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FFE93_018980	COG1253	flavin adenine dinucleotide binding
FFE93_018990	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
FFE93_018995	COG1218	3'(2'),5'-bisphosphate nucleotidase
FFE93_019000	COG0737	Belongs to the 5'-nucleotidase family
FFE93_019010	COG0545	Peptidyl-prolyl cis-trans isomerase
FFE93_019015	COG3061	Opacity-associated protein A
FFE93_019025	COG0359	binds to the 23S rRNA
FFE93_019030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FFE93_019040	COG0360	Binds together with S18 to 16S ribosomal RNA
FFE93_019055	COG1073	alpha beta
FFE93_019060	COG3650	response to hydrogen peroxide
FFE93_019065	COG1960	acyl-CoA dehydrogenase activity
FFE93_019070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFE93_019075	COG0557	exoribonuclease II activity
FFE93_019080	COG1959	2 iron, 2 sulfur cluster binding
FFE93_019085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FFE93_019090	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
FFE93_019095	COG0330	HflC and HflK could
FFE93_019100	COG0330	HflC and HflK could
FFE93_019105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FFE93_019125	COG0860	N-Acetylmuramoyl-L-alanine amidase
FFE93_019130	COG0802	atpase or kinase
FFE93_019135	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FFE93_019135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FFE93_019140	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FFE93_019165	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FFE93_019170	COG1162	GTPase activity
FFE93_019175	COG0688	phosphatidylethanolamine metabolic process
FFE93_019180	COG1511	domain protein
FFE93_019180	COG3264	Mechanosensitive ion channel
FFE93_019190	COG1053	succinate dehydrogenase
FFE93_019195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FFE93_019200	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FFE93_019205	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
FFE93_019215	COG2076	Multidrug Resistance protein
FFE93_019240	COG0459	protein refolding
FFE93_019245	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FFE93_019260	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
FFE93_019270	COG4232	protein-disulfide reductase activity
FFE93_019275	COG0493	'glutamate synthase
FFE93_019275	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FFE93_019280	COG2271	Major facilitator Superfamily
FFE93_019285	COG2721	sulfolactate sulfo-lyase activity
FFE93_019290	COG3835	regulator
FFE93_019295	COG1929	Belongs to the glycerate kinase type-1 family
FFE93_019300	COG2084	Dehydrogenase
FFE93_019310	COG1309	transcriptional regulator
FFE93_019325	COG0489	protein tyrosine kinase activity
FFE93_019335	COG1215	transferase activity, transferring glycosyl groups
FFE93_019340	COG0457	Tetratricopeptide repeat
FFE93_019350	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FFE93_019370	COG3720	iron ion transport
FFE93_019375	COG4558	Periplasmic binding protein
FFE93_019380	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FFE93_019385	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FFE93_019390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FFE93_019400	COG4774	siderophore transport
FFE93_019405	COG3264	Mechanosensitive ion channel
FFE93_019405	COG1511	domain protein
FFE93_019415	COG0612	Peptidase, M16
FFE93_019420	COG4178	(ABC) transporter
FFE93_019425	COG4771	TonB-dependent receptor
FFE93_019430	COG3712	iron ion homeostasis
FFE93_019435	COG1191	sigma factor activity
FFE93_019445	COG0425	Belongs to the sulfur carrier protein TusA family
FFE93_019450	COG2391	methyltransferase activity
FFE93_019605	COG2205	protein histidine kinase activity
FFE93_019605	COG0784	Response regulator, receiver
FFE93_019605	COG5002	protein histidine kinase activity
FFE93_019615	COG1301	dicarboxylic acid transport
FFE93_019620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FFE93_019625	COG3162	membrane
FFE93_019630	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FFE93_019675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FFE93_019690	COG1024	Enoyl-CoA hydratase
FFE93_019690	COG1250	3-hydroxyacyl-CoA dehydrogenase
FFE93_019695	COG0183	Belongs to the thiolase family
FFE93_019705	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FFE93_019725	COG0805	protein transport
FFE93_019730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFE93_019735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FFE93_019740	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FFE93_019750	COG2226	methyltransferase
FFE93_019755	COG1322	Protein conserved in bacteria
FFE93_019760	COG0586	Pfam SNARE associated Golgi protein
FFE93_019765	COG1966	Carbon starvation protein
FFE93_019775	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
FFE93_019780	COG0412	Dienelactone hydrolase
FFE93_019790	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FFE93_019795	COG0583	DNA-binding transcription factor activity
FFE93_019805	COG0679	Auxin Efflux Carrier
FFE93_019810	COG0584	glycerophosphoryl diester phosphodiesterase
FFE93_019815	COG3842	ATPase activity
FFE93_019820	COG0395	ABC-type sugar transport system, permease component
FFE93_019825	COG1175	transmembrane transport
FFE93_019830	COG1653	transport
FFE93_019870	COG0410	ABC transporter
FFE93_019875	COG0411	ABC transporter
FFE93_019880	COG4177	L-phenylalanine transmembrane transporter activity
FFE93_019885	COG0559	Belongs to the binding-protein-dependent transport system permease family
FFE93_019890	COG0683	leucine binding
FFE93_019895	COG0456	acetyltransferase
FFE93_019905	COG2177	Part of the ABC transporter FtsEX involved in
FFE93_019910	COG2884	Cell division ATP-binding protein ftsE
FFE93_019915	COG0552	protein localization to endoplasmic reticulum
FFE93_019920	COG0742	ribosomal rna small subunit methyltransferase
FFE93_019925	COG3776	membrane
FFE93_019940	COG3714	YhhN family
FFE93_019950	COG0425	Belongs to the sulfur carrier protein TusA family
FFE93_019955	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FFE93_019965	COG0247	lactate metabolic process
FFE93_019975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
FFE93_019980	COG2271	Major facilitator Superfamily
FFE93_019985	COG0584	glycerophosphoryl diester phosphodiesterase
FFE93_019990	COG0561	phosphatase activity
FFE93_019995	COG2267	carboxylic ester hydrolase activity
FFE93_020000	COG1280	lysine exporter protein (LysE YggA)
FFE93_020005	COG1280	lysine exporter protein (LysE YggA)
FFE93_020010	COG0514	ATP-dependent DNA helicase (RecQ)
FFE93_020015	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
FFE93_020020	COG2050	protein possibly involved in aromatic compounds catabolism
FFE93_020030	COG0598	Magnesium transport protein CorA
FFE93_020040	COG5564	TIM-barrel signal transduction protein
FFE93_020045	COG5441	Belongs to the UPF0261 family
FFE93_020055	COG0210	DNA helicase
FFE93_020060	COG1011	Hydrolase
FFE93_020065	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FFE93_020070	COG3159	Protein conserved in bacteria
FFE93_020075	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FFE93_020080	COG5567	small periplasmic lipoprotein
FFE93_020085	COG1965	Belongs to the frataxin family
FFE93_020090	COG3072	Adenylate cyclase
FFE93_020095	COG0181	hydroxymethylbilane synthase activity
FFE93_020100	COG1587	Uroporphyrinogen-III synthase
FFE93_020105	COG2959	enzyme of heme biosynthesis
FFE93_020110	COG3071	HemY protein
FFE93_020135	COG1113	amino acid transport
FFE93_020150	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFE93_020155	COG2244	polysaccharide biosynthetic process
FFE93_020160	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FFE93_020165	COG0456	acetyltransferase
FFE93_020170	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FFE93_020175	COG1088	dTDP-glucose 4,6-dehydratase activity
FFE93_020180	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FFE93_020185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FFE93_020190	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
FFE93_020195	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FFE93_020200	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FFE93_020205	COG3118	belongs to the thioredoxin family
FFE93_020215	COG0248	Ppx GppA phosphatase
FFE93_020230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FFE93_020240	COG3121	Chaperone
FFE93_020255	COG3121	Chaperone
FFE93_020315	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FFE93_020320	COG0583	DNA-binding transcription factor activity
FFE93_020335	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FFE93_020340	COG0129	dihydroxy-acid dehydratase activity
FFE93_020345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FFE93_020350	COG3978	acetolactate synthase activity
FFE93_020375	COG3085	chromosome segregation
FFE93_020380	COG0583	DNA-binding transcription factor activity
FFE93_020385	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_020390	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_020395	COG1129	ABC transporter
FFE93_020400	COG1879	ABC-type sugar transport system periplasmic component
FFE93_020440	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FFE93_020450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FFE93_020460	COG1309	transcriptional regulator
FFE93_020465	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE93_020475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FFE93_020475	COG0678	peroxiredoxin activity
FFE93_020480	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FFE93_020515	COG0165	Argininosuccinate lyase
FFE93_020535	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FFE93_020545	COG2814	Major facilitator Superfamily
FFE93_020550	COG1494	fructose-1,6-bisphosphatase
FFE93_020555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FFE93_020560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FFE93_020570	COG3074	FtsZ-dependent cytokinesis
FFE93_020575	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FFE93_020580	COG1575	Belongs to the MenA family. Type 1 subfamily
FFE93_020585	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FFE93_020590	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FFE93_020595	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FFE93_020600	COG1609	Transcriptional regulator
FFE93_020605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FFE93_020615	COG0254	rRNA binding
FFE93_020620	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
FFE93_020625	COG0626	cystathionine gamma-synthase activity
FFE93_020630	COG0527	aspartate kinase activity
FFE93_020630	COG0460	homoserine dehydrogenase
FFE93_020640	COG3152	Membrane
FFE93_020660	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FFE93_020665	COG3344	reverse transcriptase
FFE93_020675	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FFE93_020680	COG3678	ATP-independent chaperone mediated protein folding
FFE93_020685	COG0745	RESPONSE REGULATOR receiver
FFE93_020690	COG2205	protein histidine kinase activity
FFE93_020695	COG2169	Transcriptional regulator
FFE93_020695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FFE93_020700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FFE93_020710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FFE93_020715	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FFE93_020720	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FFE93_020725	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FFE93_020730	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FFE93_020735	COG4942	peptidase
FFE93_020740	COG2861	carbohydrate metabolic process
FFE93_020750	COG0156	8-amino-7-oxononanoate synthase activity
FFE93_020755	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FFE93_020760	COG0859	PFAM glycosyl transferase family 9
FFE93_020765	COG0859	PFAM glycosyl transferase family 9
FFE93_020770	COG1519	Transferase
FFE93_020790	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FFE93_020795	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FFE93_020810	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FFE93_020815	COG0756	dUTP diphosphatase activity
FFE93_020820	COG1309	transcriptional regulator
FFE93_020830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FFE93_020835	COG2199	diguanylate cyclase activity
FFE93_020835	COG2200	EAL domain
FFE93_020840	COG4608	Belongs to the ABC transporter superfamily
FFE93_020845	COG0444	Belongs to the ABC transporter superfamily
FFE93_020850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FFE93_020855	COG0601	transmembrane transport
FFE93_020860	COG0747	negative chemotaxis
FFE93_020865	COG3210	domain, Protein
FFE93_020870	COG2831	hemolysin activation secretion protein
FFE93_020880	COG2271	Major facilitator Superfamily
FFE93_020885	COG3851	Histidine kinase
FFE93_020890	COG2197	response regulator
FFE93_020895	COG2194	sulfuric ester hydrolase activity
FFE93_020900	COG1764	response to oxidative stress
FFE93_020915	COG2986	histidine ammonia-lyase
FFE93_020920	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
FFE93_020925	COG5001	Diguanylate cyclase
FFE93_020930	COG1024	Enoyl-CoA hydratase
FFE93_020935	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
FFE93_020945	COG2860	membrane
FFE93_020950	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FFE93_020965	COG1758	RNA polymerase activity
FFE93_020970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FFE93_020975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FFE93_020980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FFE93_020985	COG0786	glutamate:sodium symporter activity
FFE93_020990	COG2233	PERMEase
FFE93_020995	COG2982	Protein involved in outer membrane biogenesis
FFE93_021030	COG3423	Transcriptional regulator
FFE93_021045	COG2204	response regulator
FFE93_021050	COG0456	acetyltransferase
FFE93_021055	COG1490	D-aminoacyl-tRNA deacylase activity
FFE93_021060	COG1295	ribonuclease BN
FFE93_021065	COG1011	Hydrolase
FFE93_021075	COG0174	glutamine synthetase
FFE93_021080	COG3852	Histidine kinase
FFE93_021090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FFE93_021100	COG3078	GTPase activator activity
FFE93_021110	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FFE93_021115	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFE93_021115	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FFE93_021120	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FFE93_021125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FFE93_021130	COG3084	Protein conserved in bacteria
FFE93_021140	COG1763	Mo-molybdopterin cofactor biosynthetic process
FFE93_021170	COG2186	Transcriptional regulator
FFE93_021175	COG0477	Major facilitator Superfamily
FFE93_021180	COG1609	Transcriptional regulator
FFE93_021185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FFE93_021190	COG1879	ABC-type sugar transport system periplasmic component
FFE93_021195	COG1172	Belongs to the binding-protein-dependent transport system permease family
FFE93_021200	COG1129	ABC transporter
FFE93_021205	COG1869	D-ribose catabolic process
FFE93_021210	COG3158	transport of potassium into the cell
FFE93_021215	COG0714	Associated with various cellular activities
FFE93_021220	COG2425	protein containing a von Willebrand factor type A (vWA) domain
FFE93_021230	COG2502	aspartate--ammonia ligase
FFE93_021235	COG1522	sequence-specific DNA binding
FFE93_021240	COG0716	FMN binding
FFE93_021245	COG0445	tRNA wobble uridine modification
FFE93_021250	COG0357	Ribosomal RNA small subunit methyltransferase G
FFE93_021255	COG3312	ion transport
FFE93_021260	COG0356	it plays a direct role in the translocation of protons across the membrane
FFE93_021270	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FFE93_021275	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FFE93_021280	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FFE93_021285	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FFE93_021290	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FFE93_021295	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FFE93_021300	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FFE93_021305	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FFE93_021310	COG0659	secondary active sulfate transmembrane transporter activity
FFE93_021315	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FFE93_021320	COG0573	inorganic phosphate transmembrane transporter activity
FFE93_021325	COG0581	inorganic phosphate transmembrane transporter activity
FFE93_021335	COG0704	Plays a role in the regulation of phosphate uptake
FFE93_021345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FFE93_021350	COG0765	amino acid transport
FFE93_021355	COG0765	amino acid transport
FFE93_021360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FFE93_021365	COG2252	PERMEase
FFE93_021380	COG4191	Histidine kinase
FFE93_021385	COG0431	NADPH-dependent FMN reductase
FFE93_021390	COG0840	transmembrane signaling receptor activity
FFE93_021395	COG2011	ABC-type metal ion transport system permease component
FFE93_021400	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FFE93_021410	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FFE93_021415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FFE93_021420	COG0706	membrane insertase activity
FFE93_021430	COG0594	ribonuclease P activity
FFE93_021435	COG0230	Belongs to the bacterial ribosomal protein bL34 family