locus-tag	class	description
F0T03_00010	COG0716	FMN binding
F0T03_00015	COG1522	sequence-specific DNA binding
F0T03_00020	COG2502	aspartate--ammonia ligase
F0T03_00030	COG2425	protein containing a von Willebrand factor type A (vWA) domain
F0T03_00035	COG0714	Associated with various cellular activities
F0T03_00040	COG3158	transport of potassium into the cell
F0T03_00045	COG1869	D-ribose catabolic process
F0T03_00055	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_00060	COG1879	ABC-type sugar transport system periplasmic component
F0T03_00065	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0T03_00070	COG1609	Transcriptional regulator
F0T03_00075	COG0477	Major facilitator Superfamily
F0T03_00080	COG2186	Transcriptional regulator
F0T03_00110	COG1763	Mo-molybdopterin cofactor biosynthetic process
F0T03_00120	COG3084	Protein conserved in bacteria
F0T03_00125	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F0T03_00130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0T03_00135	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0T03_00135	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0T03_00140	COG0218	Necessary for normal cell division and for the maintenance of normal septation
F0T03_00145	COG3078	GTPase activator activity
F0T03_00155	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0T03_00165	COG3852	Histidine kinase
F0T03_00170	COG0174	glutamine synthetase
F0T03_00180	COG1011	Hydrolase
F0T03_00185	COG1295	ribonuclease BN
F0T03_00190	COG1490	D-aminoacyl-tRNA deacylase activity
F0T03_00195	COG0456	acetyltransferase
F0T03_00200	COG3423	Transcriptional regulator
F0T03_00215	COG2982	Protein involved in outer membrane biogenesis
F0T03_00220	COG2233	PERMEase
F0T03_00225	COG0786	glutamate:sodium symporter activity
F0T03_00230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F0T03_00235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0T03_00240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0T03_00245	COG1758	RNA polymerase activity
F0T03_00255	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F0T03_00260	COG2860	membrane
F0T03_00270	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F0T03_00275	COG1024	Enoyl-CoA hydratase
F0T03_00280	COG5001	Diguanylate cyclase
F0T03_00290	COG1561	YicC-like family, N-terminal region
F0T03_00300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
F0T03_00305	COG1309	transcriptional regulator
F0T03_00310	COG0756	dUTP diphosphatase activity
F0T03_00315	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F0T03_00330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
F0T03_00335	COG0267	Belongs to the bacterial ribosomal protein bL33 family
F0T03_00340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
F0T03_00345	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
F0T03_00355	COG1519	Transferase
F0T03_00360	COG0859	PFAM glycosyl transferase family 9
F0T03_00365	COG0859	PFAM glycosyl transferase family 9
F0T03_00370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0T03_00375	COG0156	8-amino-7-oxononanoate synthase activity
F0T03_00385	COG2861	carbohydrate metabolic process
F0T03_00390	COG4942	peptidase
F0T03_00395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F0T03_00400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0T03_00405	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F0T03_00410	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
F0T03_00415	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
F0T03_00420	COG1045	serine acetyltransferase
F0T03_00425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F0T03_00430	COG2169	Transcriptional regulator
F0T03_00430	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0T03_00435	COG2205	protein histidine kinase activity
F0T03_00440	COG0745	RESPONSE REGULATOR receiver
F0T03_00445	COG3678	ATP-independent chaperone mediated protein folding
F0T03_00450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F0T03_00460	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F0T03_00470	COG0149	triose-phosphate isomerase activity
F0T03_00480	COG3152	Membrane
F0T03_00490	COG2814	Major facilitator Superfamily
F0T03_00495	COG1494	fructose-1,6-bisphosphatase
F0T03_00505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F0T03_00520	COG3074	FtsZ-dependent cytokinesis
F0T03_00525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F0T03_00530	COG1575	Belongs to the MenA family. Type 1 subfamily
F0T03_00535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
F0T03_00540	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
F0T03_00545	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F0T03_00550	COG1609	Transcriptional regulator
F0T03_00555	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F0T03_00560	COG0254	rRNA binding
F0T03_00565	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
F0T03_00570	COG0626	cystathionine gamma-synthase activity
F0T03_00575	COG0527	aspartate kinase activity
F0T03_00575	COG0460	homoserine dehydrogenase
F0T03_00590	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
F0T03_00600	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
F0T03_00605	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F0T03_00610	COG0165	Argininosuccinate lyase
F0T03_00645	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0T03_00650	COG0678	peroxiredoxin activity
F0T03_00650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F0T03_00660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0T03_00665	COG1309	transcriptional regulator
F0T03_00675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0T03_00685	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F0T03_00730	COG1879	ABC-type sugar transport system periplasmic component
F0T03_00735	COG1129	ABC transporter
F0T03_00740	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_00745	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_00750	COG0583	DNA-binding transcription factor activity
F0T03_00755	COG3085	chromosome segregation
F0T03_00775	COG3978	acetolactate synthase activity
F0T03_00780	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0T03_00785	COG0129	dihydroxy-acid dehydratase activity
F0T03_00790	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0T03_00795	COG0583	DNA-binding transcription factor activity
F0T03_00800	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
F0T03_00810	COG3121	Chaperone
F0T03_00825	COG3121	Chaperone
F0T03_00835	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0T03_00850	COG0248	Ppx GppA phosphatase
F0T03_00860	COG3118	belongs to the thioredoxin family
F0T03_00865	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
F0T03_00870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F0T03_00875	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
F0T03_00880	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F0T03_00885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F0T03_00890	COG1088	dTDP-glucose 4,6-dehydratase activity
F0T03_00895	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
F0T03_00900	COG0456	acetyltransferase
F0T03_00905	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0T03_00910	COG2244	polysaccharide biosynthetic process
F0T03_00915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F0T03_00930	COG1113	amino acid transport
F0T03_00955	COG3071	HemY protein
F0T03_00960	COG2959	enzyme of heme biosynthesis
F0T03_00965	COG1587	Uroporphyrinogen-III synthase
F0T03_00970	COG0181	hydroxymethylbilane synthase activity
F0T03_00975	COG3072	Adenylate cyclase
F0T03_00980	COG1965	Belongs to the frataxin family
F0T03_00985	COG5567	small periplasmic lipoprotein
F0T03_00990	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F0T03_00995	COG3159	Protein conserved in bacteria
F0T03_01000	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F0T03_01005	COG1011	Hydrolase
F0T03_01010	COG0210	DNA helicase
F0T03_01020	COG5441	Belongs to the UPF0261 family
F0T03_01025	COG5564	TIM-barrel signal transduction protein
F0T03_01035	COG0598	Magnesium transport protein CorA
F0T03_01045	COG2050	protein possibly involved in aromatic compounds catabolism
F0T03_01050	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
F0T03_01055	COG0514	ATP-dependent DNA helicase (RecQ)
F0T03_01060	COG1280	lysine exporter protein (LysE YggA)
F0T03_01070	COG2267	carboxylic ester hydrolase activity
F0T03_01075	COG0561	phosphatase activity
F0T03_01080	COG0584	glycerophosphoryl diester phosphodiesterase
F0T03_01085	COG2271	Major facilitator Superfamily
F0T03_01090	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F0T03_01095	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
F0T03_01100	COG0247	lactate metabolic process
F0T03_01110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
F0T03_01115	COG0425	Belongs to the sulfur carrier protein TusA family
F0T03_01125	COG3714	YhhN family
F0T03_01140	COG3776	membrane
F0T03_01145	COG0742	ribosomal rna small subunit methyltransferase
F0T03_01150	COG0552	protein localization to endoplasmic reticulum
F0T03_01155	COG2884	Cell division ATP-binding protein ftsE
F0T03_01160	COG2177	Part of the ABC transporter FtsEX involved in
F0T03_01175	COG0683	leucine binding
F0T03_01180	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0T03_01185	COG4177	L-phenylalanine transmembrane transporter activity
F0T03_01190	COG0411	ABC transporter
F0T03_01195	COG0410	ABC transporter
F0T03_01230	COG1653	transport
F0T03_01235	COG1175	transmembrane transport
F0T03_01240	COG0395	ABC-type sugar transport system, permease component
F0T03_01245	COG3842	ATPase activity
F0T03_01250	COG0584	glycerophosphoryl diester phosphodiesterase
F0T03_01255	COG0679	Auxin Efflux Carrier
F0T03_01265	COG0583	DNA-binding transcription factor activity
F0T03_01270	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F0T03_01275	COG0412	Dienelactone hydrolase
F0T03_01280	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
F0T03_01290	COG1966	Carbon starvation protein
F0T03_01295	COG0586	Pfam SNARE associated Golgi protein
F0T03_01300	COG1322	Protein conserved in bacteria
F0T03_01305	COG2226	methyltransferase
F0T03_01315	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F0T03_01320	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0T03_01325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0T03_01330	COG0805	protein transport
F0T03_01350	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
F0T03_01360	COG0183	Belongs to the thiolase family
F0T03_01365	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0T03_01365	COG1024	Enoyl-CoA hydratase
F0T03_01375	COG1739	Uncharacterized protein family UPF0029
F0T03_01380	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F0T03_01420	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F0T03_01425	COG3162	membrane
F0T03_01430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F0T03_01435	COG1301	dicarboxylic acid transport
F0T03_01600	COG2391	methyltransferase activity
F0T03_01605	COG0425	Belongs to the sulfur carrier protein TusA family
F0T03_01610	COG1511	domain protein
F0T03_01610	COG3264	Mechanosensitive ion channel
F0T03_01615	COG4774	siderophore transport
F0T03_01620	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F0T03_01650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0T03_01655	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F0T03_01660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0T03_01665	COG4558	Periplasmic binding protein
F0T03_01670	COG3720	iron ion transport
F0T03_01690	COG3721	Heme iron utilization protein
F0T03_01725	COG2831	hemolysin activation secretion protein
F0T03_01730	COG3210	domain, Protein
F0T03_01780	COG3210	domain, Protein
F0T03_01850	COG0305	Participates in initiation and elongation during chromosome replication
F0T03_01885	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F0T03_01950	COG1192	Involved in chromosome partitioning
F0T03_02010	COG1204	response to ionizing radiation
F0T03_02120	COG2132	Multicopper oxidase
F0T03_02135	COG2205	protein histidine kinase activity
F0T03_02140	COG0745	RESPONSE REGULATOR receiver
F0T03_02145	COG1276	copper resistance
F0T03_02150	COG2372	response to copper ion
F0T03_02155	COG3667	copper resistance
F0T03_02160	COG2132	Multicopper oxidase
F0T03_02175	COG0739	heme binding
F0T03_02205	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_02220	COG0745	RESPONSE REGULATOR receiver
F0T03_02250	COG1309	transcriptional regulator
F0T03_02260	COG2084	Dehydrogenase
F0T03_02265	COG1929	Belongs to the glycerate kinase type-1 family
F0T03_02270	COG3835	regulator
F0T03_02280	COG0493	'glutamate synthase
F0T03_02280	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F0T03_02285	COG3383	formate dehydrogenase (NAD+) activity
F0T03_02290	COG4232	protein-disulfide reductase activity
F0T03_02300	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F0T03_02315	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
F0T03_02320	COG0459	protein refolding
F0T03_02340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F0T03_02350	COG2076	Multidrug Resistance protein
F0T03_02360	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
F0T03_02365	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
F0T03_02370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F0T03_02375	COG1053	succinate dehydrogenase
F0T03_02380	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F0T03_02385	COG1511	domain protein
F0T03_02385	COG3264	Mechanosensitive ion channel
F0T03_02390	COG0688	phosphatidylethanolamine metabolic process
F0T03_02395	COG1162	GTPase activity
F0T03_02400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F0T03_02425	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F0T03_02430	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F0T03_02430	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F0T03_02435	COG0802	atpase or kinase
F0T03_02440	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0T03_02445	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F0T03_02450	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
F0T03_02455	COG1923	regulation of RNA biosynthetic process
F0T03_02460	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F0T03_02465	COG0330	HflC and HflK could
F0T03_02470	COG0330	HflC and HflK could
F0T03_02475	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
F0T03_02480	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F0T03_02485	COG1959	2 iron, 2 sulfur cluster binding
F0T03_02490	COG0557	exoribonuclease II activity
F0T03_02495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0T03_02500	COG1960	acyl-CoA dehydrogenase activity
F0T03_02505	COG3650	response to hydrogen peroxide
F0T03_02510	COG1073	alpha beta
F0T03_02525	COG0360	Binds together with S18 to 16S ribosomal RNA
F0T03_02530	COG2965	DNA replication, synthesis of RNA primer
F0T03_02535	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
F0T03_02540	COG0359	binds to the 23S rRNA
F0T03_02550	COG3061	Opacity-associated protein A
F0T03_02555	COG0545	Peptidyl-prolyl cis-trans isomerase
F0T03_02565	COG0737	Belongs to the 5'-nucleotidase family
F0T03_02570	COG1218	3'(2'),5'-bisphosphate nucleotidase
F0T03_02575	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
F0T03_02585	COG1253	flavin adenine dinucleotide binding
F0T03_02590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
F0T03_02595	COG0729	surface antigen
F0T03_02605	COG2105	PFAM AIG2 family protein
F0T03_02610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F0T03_02615	COG0840	transmembrane signaling receptor activity
F0T03_02620	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
F0T03_02625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F0T03_02640	COG1438	arginine binding
F0T03_02645	COG0039	L-malate dehydrogenase activity
F0T03_02650	COG3423	Transcriptional regulator
F0T03_02660	COG0142	geranyltranstransferase activity
F0T03_02675	COG0697	spore germination
F0T03_02680	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
F0T03_02685	COG0642	Histidine kinase
F0T03_02690	COG0745	RESPONSE REGULATOR receiver
F0T03_02695	COG2027	D-alanyl-D-alanine carboxypeptidase
F0T03_02700	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0T03_02705	COG1534	Rna-binding protein
F0T03_02710	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
F0T03_02715	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F0T03_02720	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F0T03_02725	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F0T03_02730	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F0T03_02745	COG0779	Required for maturation of 30S ribosomal subunits
F0T03_02750	COG0195	Participates in both transcription termination and antitermination
F0T03_02755	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
F0T03_02760	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
F0T03_02765	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F0T03_02775	COG1185	polyribonucleotide nucleotidyltransferase activity
F0T03_02790	COG0513	Belongs to the DEAD box helicase family
F0T03_02795	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F0T03_02805	COG0814	amino acid
F0T03_02810	COG3681	Belongs to the UPF0597 family
F0T03_02835	COG3153	acetyltransferase
F0T03_02845	COG0531	amino acid
F0T03_02850	COG1982	Orn Lys Arg decarboxylase major
F0T03_02870	COG1653	transport
F0T03_02880	COG0395	ABC-type sugar transport system, permease component
F0T03_02885	COG3842	ATPase activity
F0T03_02895	COG3787	Belongs to the UPF0306 family
F0T03_02900	COG0702	epimerase
F0T03_02905	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
F0T03_02910	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
F0T03_02915	COG3454	Phosphonate metabolism
F0T03_02920	COG4778	phosphonate C-P lyase system protein PhnL
F0T03_02925	COG4107	phosphonate C-P lyase system protein PhnK
F0T03_02930	COG3627	carbon phosphorus lyase activity
F0T03_02935	COG3626	phosphonate metabolism
F0T03_02940	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
F0T03_02945	COG3624	Phosphonate C-P lyase system protein PhnG
F0T03_02950	COG2188	Transcriptional regulator
F0T03_02965	COG0583	DNA-binding transcription factor activity
F0T03_02970	COG2249	NAD(P)H dehydrogenase (quinone) activity
F0T03_02975	COG4608	Belongs to the ABC transporter superfamily
F0T03_02980	COG0444	Belongs to the ABC transporter superfamily
F0T03_02990	COG0601	transmembrane transport
F0T03_03000	COG2731	YhcH YjgK YiaL family protein
F0T03_03010	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
F0T03_03030	COG2927	DNA polymerase III (CHI subunit)
F0T03_03035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
F0T03_03040	COG0795	lipopolysaccharide-transporting ATPase activity
F0T03_03045	COG0795	lipopolysaccharide-transporting ATPase activity
F0T03_03055	COG0582	viral genome integration into host DNA
F0T03_03125	COG3596	GTP binding
F0T03_03135	COG2378	regulation of single-species biofilm formation
F0T03_03155	COG2003	Belongs to the UPF0758 family
F0T03_03205	COG0454	-acetyltransferase
F0T03_03225	COG3272	Protein of unknown function (DUF1722)
F0T03_03230	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F0T03_03235	COG1830	Aldolase
F0T03_03240	COG1879	ABC-type sugar transport system periplasmic component
F0T03_03245	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_03250	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_03255	COG1129	ABC transporter
F0T03_03265	COG2390	Transcriptional regulator
F0T03_03270	COG1070	Carbohydrate kinase
F0T03_03275	COG0859	PFAM glycosyl transferase family 9
F0T03_03290	COG2235	arginine
F0T03_03300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_03305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0T03_03315	COG2376	Dihydroxyacetone kinase
F0T03_03320	COG1461	Dihydroxyacetone kinase
F0T03_03325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F0T03_03325	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0T03_03325	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
F0T03_03335	COG2192	nodulation
F0T03_03395	COG3706	GGDEF domain
F0T03_03420	COG0583	DNA-binding transcription factor activity
F0T03_03425	COG0667	Aldo Keto reductase
F0T03_03430	COG2813	Specifically methylates the guanine in position
F0T03_03435	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
F0T03_03440	COG0456	acetyltransferase
F0T03_03445	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F0T03_03450	COG2823	Periplasmic or secreted lipoprotein
F0T03_03460	COG4667	esterase of the alpha-beta hydrolase superfamily
F0T03_03465	COG0084	hydrolase, TatD family'
F0T03_03470	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F0T03_03475	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F0T03_03480	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
F0T03_03485	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F0T03_03495	COG3726	membrane protein affecting hemolysin expression
F0T03_03500	COG0560	Phosphoserine phosphatase
F0T03_03515	COG0604	alcohol dehydrogenase
F0T03_03525	COG0488	(ABC) transporter
F0T03_03530	COG2885	chlorophyll binding
F0T03_03535	COG2199	diguanylate cyclase activity
F0T03_03545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F0T03_03550	COG0741	lytic transglycosylase activity
F0T03_03555	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
F0T03_03560	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
F0T03_03565	COG0406	alpha-ribazole phosphatase activity
F0T03_03570	COG2207	Transcriptional regulator
F0T03_03570	COG3708	Transcriptional regulator
F0T03_03575	COG3045	CreA protein
F0T03_03580	COG0745	RESPONSE REGULATOR receiver
F0T03_03595	COG0083	homoserine kinase activity
F0T03_03605	COG3022	response to hydroperoxide
F0T03_03615	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F0T03_03620	COG0521	Mo-molybdopterin cofactor biosynthetic process
F0T03_03635	COG1584	GPR1 FUN34 yaaH family protein
F0T03_03645	COG0484	heat shock protein binding
F0T03_03650	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F0T03_03655	COG0583	DNA-binding transcription factor activity
F0T03_03675	COG0196	riboflavin kinase activity
F0T03_03680	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F0T03_03685	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
F0T03_03690	COG1047	Peptidyl-prolyl cis-trans
F0T03_03695	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
F0T03_03700	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
F0T03_03705	COG0505	Belongs to the CarA family
F0T03_03710	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
F0T03_03715	COG1280	lysine exporter protein (LysE YggA)
F0T03_03720	COG2966	Psort location CytoplasmicMembrane, score
F0T03_03725	COG3610	response to peptide
F0T03_03730	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F0T03_03740	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F0T03_03745	COG2967	ApaG domain
F0T03_03755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F0T03_03760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0T03_03765	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F0T03_03780	COG0564	pseudouridine synthase activity
F0T03_03785	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
F0T03_03790	COG0417	DNA replication proofreading
F0T03_03795	COG0586	Pfam SNARE associated Golgi protein
F0T03_03805	COG1178	ABC-type Fe3 transport system permease component
F0T03_03810	COG4143	(ABC) transporter
F0T03_03815	COG4533	DNA binding
F0T03_03820	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F0T03_03830	COG2814	Major facilitator Superfamily
F0T03_03835	COG0814	amino acid
F0T03_03840	COG3033	Beta-eliminating lyase
F0T03_03855	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
F0T03_03860	COG0473	3-isopropylmalate dehydrogenase activity
F0T03_03865	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F0T03_03880	COG1022	Amp-dependent synthetase and ligase
F0T03_03885	COG0028	Belongs to the TPP enzyme family
F0T03_03895	COG1609	Transcriptional regulator
F0T03_03905	COG2001	Belongs to the MraZ family
F0T03_03910	COG0275	rRNA processing
F0T03_03915	COG3116	cell division
F0T03_03920	COG0768	penicillin binding
F0T03_03925	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F0T03_03930	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F0T03_03935	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F0T03_03945	COG0772	Belongs to the SEDS family
F0T03_03950	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
F0T03_03955	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F0T03_03965	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F0T03_03970	COG0849	cell division
F0T03_03975	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F0T03_03995	COG0653	protein targeting
F0T03_04005	COG0494	nUDIX hydrolase
F0T03_04010	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F0T03_04020	COG0237	dephospho-CoA kinase activity
F0T03_04030	COG0516	GMP reductase activity
F0T03_04040	COG1459	type II secretion system
F0T03_04045	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F0T03_04050	COG4969	Belongs to the N-Me-Phe pilin family
F0T03_04060	COG3023	N-Acetylmuramoyl-L-alanine amidase
F0T03_04065	COG3725	Membrane protein required for beta-lactamase induction
F0T03_04070	COG1113	amino acid transport
F0T03_04080	COG2186	Transcriptional regulator
F0T03_04085	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
F0T03_04090	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0T03_04095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0T03_04105	COG4977	sequence-specific DNA binding
F0T03_04115	COG1049	propionate catabolic process, 2-methylcitrate cycle
F0T03_04120	COG3112	Uncharacterised protein family (UPF0231)
F0T03_04125	COG0697	spore germination
F0T03_04130	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
F0T03_04135	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
F0T03_04145	COG2132	Multicopper oxidase
F0T03_04150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
F0T03_04155	COG0288	reversible hydration of carbon dioxide
F0T03_04160	COG1131	(ABC) transporter
F0T03_04165	COG0842	Transport permease protein
F0T03_04170	COG0726	polysaccharide deacetylase
F0T03_04175	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
F0T03_04180	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
F0T03_04185	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
F0T03_04190	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F0T03_04195	COG0617	tRNA 3'-terminal CCA addition
F0T03_04205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F0T03_04210	COG1489	DNA binding
F0T03_04215	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
F0T03_04220	COG1643	Atp-dependent helicase
F0T03_04225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0T03_04230	COG1120	ATPase activity
F0T03_04235	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0T03_04240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0T03_04245	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
F0T03_04255	COG0316	Belongs to the HesB IscA family
F0T03_04265	COG2860	membrane
F0T03_04275	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F0T03_04280	COG0232	Belongs to the dGTPase family. Type 2 subfamily
F0T03_04285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0T03_04290	COG4999	Histidine kinase
F0T03_04290	COG3850	Histidine kinase
F0T03_04290	COG3437	response regulator, receiver
F0T03_04290	COG2205	protein histidine kinase activity
F0T03_04295	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0T03_04300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F0T03_04305	COG3956	TIGRFAM MazG family protein
F0T03_04310	COG0504	CTP synthase activity
F0T03_04315	COG0148	phosphopyruvate hydratase activity
F0T03_04325	COG0602	queuosine metabolic process
F0T03_04330	COG0720	synthase
F0T03_04340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F0T03_04345	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0T03_04350	COG0175	sulfate reduction
F0T03_04355	COG2234	aminopeptidase activity
F0T03_04360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F0T03_04360	COG1648	precorrin-2 dehydrogenase activity
F0T03_04365	COG0175	sulfate reduction
F0T03_04370	COG2895	sulfate adenylyltransferase (ATP) activity
F0T03_04375	COG0529	Catalyzes the synthesis of activated sulfate
F0T03_04390	COG0765	amino acid transport
F0T03_04400	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F0T03_04410	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
F0T03_04415	COG0585	pseudouridine synthase activity
F0T03_04420	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F0T03_04425	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F0T03_04430	COG1388	LysM domain
F0T03_04430	COG4942	peptidase
F0T03_04435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F0T03_04440	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
F0T03_04465	COG3188	usher protein
F0T03_04470	COG3121	Chaperone
F0T03_04485	COG3539	Fimbrial protein
F0T03_04490	COG3539	Fimbrial protein
F0T03_04505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0T03_04520	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_04525	COG0577	efflux transmembrane transporter activity
F0T03_04525	COG1136	(ABC) transporter
F0T03_04530	COG1538	Outer membrane efflux protein
F0T03_04550	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_04555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0T03_04565	COG1858	cytochrome C peroxidase
F0T03_04570	COG4948	Mandelate Racemase Muconate Lactonizing
F0T03_04575	COG0747	negative chemotaxis
F0T03_04580	COG0601	transmembrane transport
F0T03_04590	COG0444	Belongs to the ABC transporter superfamily
F0T03_04595	COG4608	Belongs to the ABC transporter superfamily
F0T03_04600	COG0583	DNA-binding transcription factor activity
F0T03_04605	COG2610	gluconate transmembrane transporter activity
F0T03_04610	COG3048	D-serine ammonia-lyase activity
F0T03_04620	COG0765	amino acid transport
F0T03_04625	COG0765	amino acid transport
F0T03_04630	COG1126	abc transporter atp-binding protein
F0T03_04635	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0T03_04650	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
F0T03_04655	COG0640	Transcriptional regulator
F0T03_04715	COG0410	ABC transporter
F0T03_04720	COG1137	ATPase activity
F0T03_04725	COG4177	L-phenylalanine transmembrane transporter activity
F0T03_04730	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0T03_04740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F0T03_04740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F0T03_04745	COG1070	Carbohydrate kinase
F0T03_04750	COG3623	hexulose-6-phosphate isomerase
F0T03_04760	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_04765	COG1129	ABC transporter
F0T03_04775	COG1349	DNA-binding transcription factor activity
F0T03_04780	COG0235	Class ii aldolase
F0T03_04785	COG1349	DNA-binding transcription factor activity
F0T03_04795	COG1070	Carbohydrate kinase
F0T03_04805	COG0738	Major facilitator superfamily
F0T03_04810	COG0235	Class ii aldolase
F0T03_04815	COG1454	alcohol dehydrogenase
F0T03_04820	COG0243	molybdopterin cofactor binding
F0T03_04825	COG0437	4 iron, 4 sulfur cluster binding
F0T03_04830	COG3302	dmso reductase anchor subunit
F0T03_04835	COG3381	protein complex oligomerization
F0T03_04845	COG1609	Transcriptional regulator
F0T03_04855	COG1129	ABC transporter
F0T03_04860	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_04865	COG3959	Transketolase, thiamine diphosphate binding domain
F0T03_04870	COG3958	Transketolase
F0T03_04875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F0T03_04900	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
F0T03_04905	COG2137	regulation of response to DNA damage stimulus
F0T03_04910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F0T03_04915	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
F0T03_04940	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0T03_04945	COG1238	metal cluster binding
F0T03_04950	COG2918	glutathione biosynthetic process
F0T03_04955	COG1854	S-ribosylhomocysteine lyase activity
F0T03_04960	COG4536	flavin adenine dinucleotide binding
F0T03_04965	COG4137	Cytochrome C assembly protein
F0T03_04970	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F0T03_04975	COG0228	four-way junction DNA binding
F0T03_04980	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F0T03_04985	COG0336	Belongs to the RNA methyltransferase TrmD family
F0T03_04990	COG0335	large ribosomal subunit rRNA binding
F0T03_04995	COG3137	Salt-induced outer membrane protein
F0T03_05000	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
F0T03_05005	COG3279	Response regulator of the LytR AlgR family
F0T03_05010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F0T03_05015	COG0287	Prephenate dehydrogenase
F0T03_05015	COG1605	Chorismate mutase
F0T03_05020	COG0077	Prephenate dehydratase
F0T03_05020	COG1605	Chorismate mutase
F0T03_05025	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F0T03_05030	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0T03_05040	COG0564	pseudouridine synthase activity
F0T03_05050	COG0542	response to heat
F0T03_05085	COG0656	L-ascorbic acid biosynthetic process
F0T03_05095	COG3021	interspecies interaction between organisms
F0T03_05100	COG1388	LysM domain
F0T03_05100	COG0741	lytic transglycosylase activity
F0T03_05105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0T03_05110	COG2226	methyltransferase
F0T03_05115	COG0328	RNA-DNA hybrid ribonuclease activity
F0T03_05120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F0T03_05130	COG2113	Glycine betaine
F0T03_05135	COG4176	ABC-type proline glycine betaine transport system permease component
F0T03_05145	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F0T03_05155	COG1780	Probably involved in ribonucleotide reductase function
F0T03_05165	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0T03_05175	COG4575	ribosome binding
F0T03_05190	COG2207	Transcriptional regulator
F0T03_05210	COG1278	Cold shock
F0T03_05250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0T03_05255	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F0T03_05280	COG0804	urea catabolic process
F0T03_05285	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
F0T03_05290	COG0830	nickel cation binding
F0T03_05295	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F0T03_05300	COG0829	nickel cation binding
F0T03_05305	COG4413	Urea transporter
F0T03_05315	COG3039	Transposase
F0T03_05330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F0T03_05335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0T03_05345	COG0667	Aldo Keto reductase
F0T03_05350	COG2133	pyrroloquinoline quinone binding
F0T03_05355	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F0T03_05360	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F0T03_05365	COG2723	6-phospho-beta-galactosidase activity
F0T03_05370	COG1447	Phosphotransferase system cellobiose-specific component IIA
F0T03_05375	COG1917	Cupin 2, conserved barrel domain protein
F0T03_05375	COG2169	Transcriptional regulator
F0T03_05380	COG3394	polysaccharide catabolic process
F0T03_05440	COG0582	viral genome integration into host DNA
F0T03_05455	COG2867	negative regulation of translational initiation
F0T03_05465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0T03_05470	COG0497	DNA recombination
F0T03_05475	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F0T03_05480	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
F0T03_05485	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
F0T03_05490	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
F0T03_05505	COG0513	Belongs to the DEAD box helicase family
F0T03_05510	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
F0T03_05515	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
F0T03_05525	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
F0T03_05535	COG3086	response to oxidative stress
F0T03_05545	COG3039	Transposase
F0T03_05550	COG0481	GTPase activity
F0T03_05555	COG0681	Belongs to the peptidase S26 family
F0T03_05560	COG0571	ribonuclease III activity
F0T03_05565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F0T03_05570	COG1381	Involved in DNA repair and RecF pathway recombination
F0T03_05575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F0T03_05585	COG2610	gluconate transmembrane transporter activity
F0T03_05590	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F0T03_05595	COG1737	Transcriptional regulator
F0T03_05605	COG0560	Phosphoserine phosphatase
F0T03_05615	COG0590	tRNA wobble adenosine to inosine editing
F0T03_05620	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
F0T03_05635	COG2205	protein histidine kinase activity
F0T03_05640	COG3170	Tfp pilus assembly protein FimV
F0T03_05645	COG2204	response regulator
F0T03_05650	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F0T03_05650	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0T03_05655	COG0347	Belongs to the P(II) protein family
F0T03_05670	COG1735	metal-dependent hydrolase with the TIM-barrel fold
F0T03_05675	COG3457	Alanine racemase
F0T03_05690	COG3039	Transposase
F0T03_05700	COG1017	nitric oxide dioxygenase activity
F0T03_05700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0T03_05705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
F0T03_05710	COG2814	Major facilitator Superfamily
F0T03_05715	COG3711	transcriptional antiterminator
F0T03_05720	COG3683	transport system, periplasmic component
F0T03_05725	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
F0T03_05730	COG0483	inositol monophosphate 1-phosphatase activity
F0T03_05735	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
F0T03_05740	COG1959	2 iron, 2 sulfur cluster binding
F0T03_05750	COG0822	iron-sulfur transferase activity
F0T03_05760	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
F0T03_05765	COG0443	Heat shock 70 kDa protein
F0T03_05770	COG0633	Ferredoxin
F0T03_05775	COG2975	iron-sulfur cluster assembly
F0T03_05790	COG2373	Large extracellular alpha-helical protein
F0T03_05795	COG4953	penicillin-binding protein 1C
F0T03_05820	COG1426	Protein conserved in bacteria
F0T03_05825	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
F0T03_05830	COG0124	histidyl-tRNA synthetase
F0T03_05835	COG2976	Protein conserved in bacteria
F0T03_05840	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F0T03_05845	COG1160	GTP binding
F0T03_05855	COG1645	bacterial-type flagellum-dependent swarming motility
F0T03_05860	COG1570	exodeoxyribonuclease VII activity
F0T03_05870	COG0516	GMP reductase activity
F0T03_05870	COG0517	IMP dehydrogenase activity
F0T03_05875	COG0519	Catalyzes the synthesis of GMP from XMP
F0T03_05875	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F0T03_05905	COG0351	phosphomethylpyrimidine kinase
F0T03_05925	COG1349	DNA-binding transcription factor activity
F0T03_05930	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0T03_05935	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_05950	COG3730	PTS system glucitol sorbitol-specific
F0T03_05955	COG1597	lipid kinase activity
F0T03_05965	COG3422	double-strand break repair
F0T03_05970	COG0745	RESPONSE REGULATOR receiver
F0T03_05975	COG2205	protein histidine kinase activity
F0T03_05980	COG0477	Major facilitator Superfamily
F0T03_05990	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0T03_06000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_06005	COG3539	Fimbrial protein
F0T03_06015	COG3121	Chaperone
F0T03_06025	COG0443	Heat shock 70 kDa protein
F0T03_06030	COG5001	Diguanylate cyclase
F0T03_06030	COG3447	MASE1 domain protein
F0T03_06030	COG5002	protein histidine kinase activity
F0T03_06035	COG2239	Acts as a magnesium transporter
F0T03_06045	COG0248	Ppx GppA phosphatase
F0T03_06050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F0T03_06055	COG0573	inorganic phosphate transmembrane transporter activity
F0T03_06060	COG0581	inorganic phosphate transmembrane transporter activity
F0T03_06070	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0T03_06075	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F0T03_06080	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
F0T03_06085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
F0T03_06090	COG2233	PERMEase
F0T03_06095	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F0T03_06100	COG1393	Belongs to the ArsC family
F0T03_06105	COG4783	chaperone-mediated protein folding
F0T03_06110	COG0628	permease
F0T03_06115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F0T03_06120	COG2716	regulation of RNA biosynthetic process
F0T03_06125	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0T03_06130	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
F0T03_06135	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
F0T03_06140	COG2321	neutral zinc metallopeptidase
F0T03_06145	COG2707	UPF0756 membrane protein
F0T03_06150	COG1444	tRNA N-acetyltransferase activity
F0T03_06155	COG0400	carboxylic ester hydrolase activity
F0T03_06165	COG1876	peptidase activity
F0T03_06170	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F0T03_06175	COG1393	Belongs to the ArsC family
F0T03_06185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0T03_06195	COG2197	response regulator
F0T03_06205	COG3062	negative regulation of establishment of protein localization
F0T03_06210	COG0243	molybdopterin cofactor binding
F0T03_06215	COG3043	anaerobic respiration
F0T03_06220	COG3005	denitrification pathway
F0T03_06225	COG0494	nUDIX hydrolase
F0T03_06235	COG1671	Belongs to the UPF0178 family
F0T03_06240	COG0408	coproporphyrinogen oxidase activity
F0T03_06245	COG0456	acetyltransferase
F0T03_06335	COG3111	PFAM Bacterial OB fold (BOF) protein
F0T03_06345	COG2837	iron assimilation
F0T03_06350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F0T03_06365	COG2731	YhcH YjgK YiaL family protein
F0T03_06370	COG1737	Transcriptional regulator
F0T03_06385	COG4150	thiosulfate binding
F0T03_06390	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F0T03_06395	COG4208	sulfate ABC transporter
F0T03_06415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_06420	COG0745	RESPONSE REGULATOR receiver
F0T03_06425	COG2205	protein histidine kinase activity
F0T03_06430	COG2190	(PTS) system
F0T03_06435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F0T03_06440	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0T03_06445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F0T03_06450	COG0582	viral genome integration into host DNA
F0T03_06495	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F0T03_06500	COG5532	Uncharacterized conserved protein (DUF2303)
F0T03_06565	COG3645	SOS response
F0T03_06565	COG3646	Phage regulatory protein
F0T03_06570	COG1403	HNH endonuclease
F0T03_06580	COG1724	mRNA binding
F0T03_06585	COG1598	PFAM Uncharacterised protein family UPF0150
F0T03_06600	COG3179	chitinase
F0T03_06680	COG4386	tail sheath protein
F0T03_06720	COG4381	Mu-like prophage protein gp46
F0T03_06725	COG3299	homolog of phage Mu protein gp47
F0T03_06755	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
F0T03_06765	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F0T03_06770	COG3530	Putative quorum-sensing-regulated virulence factor
F0T03_06800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0T03_06830	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F0T03_06835	COG1914	H( )-stimulated, divalent metal cation uptake system
F0T03_06845	COG0667	Aldo Keto reductase
F0T03_06850	COG3961	Belongs to the TPP enzyme family
F0T03_06865	COG0837	glucose binding
F0T03_06870	COG2223	nitrite transmembrane transporter activity
F0T03_06875	COG3279	Response regulator of the LytR AlgR family
F0T03_06880	COG3275	phosphorelay sensor kinase activity
F0T03_06895	COG0436	Aminotransferase
F0T03_06900	COG3038	cytochrome b561
F0T03_06910	COG1598	PFAM Uncharacterised protein family UPF0150
F0T03_06935	COG3381	protein complex oligomerization
F0T03_06945	COG0437	4 iron, 4 sulfur cluster binding
F0T03_06950	COG0243	molybdopterin cofactor binding
F0T03_06965	COG2723	6-phospho-beta-galactosidase activity
F0T03_06980	COG1280	lysine exporter protein (LysE YggA)
F0T03_07000	COG2951	lytic endotransglycosylase activity
F0T03_07005	COG0531	amino acid
F0T03_07025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F0T03_07030	COG1127	ABC transporter
F0T03_07045	COG3038	cytochrome b561
F0T03_07050	COG2353	YceI-like domain
F0T03_07055	COG1609	Transcriptional regulator
F0T03_07060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0T03_07060	COG1263	PTS System
F0T03_07065	COG2723	6-phospho-beta-galactosidase activity
F0T03_07075	COG1695	Transcriptional regulator
F0T03_07080	COG2824	Alkylphosphonate utilization operon protein PhnA
F0T03_07085	COG0583	DNA-binding transcription factor activity
F0T03_07110	COG1674	ftsk spoiiie
F0T03_07125	COG3423	Transcriptional regulator
F0T03_07150	COG2003	Belongs to the UPF0758 family
F0T03_07155	COG4974	Belongs to the 'phage' integrase family
F0T03_07205	COG2826	transposase and inactivated derivatives, IS30 family
F0T03_07215	COG1902	pentaerythritol trinitrate reductase activity
F0T03_07220	COG1073	alpha beta
F0T03_07240	COG0583	DNA-binding transcription factor activity
F0T03_07260	COG0582	viral genome integration into host DNA
F0T03_07270	COG2116	formate transmembrane transporter activity
F0T03_07280	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F0T03_07285	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F0T03_07290	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
F0T03_07295	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
F0T03_07300	COG1138	Cytochrome C-type biogenesis protein
F0T03_07305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T03_07315	COG3088	subunit of a heme lyase
F0T03_07315	COG4235	cytochrome complex assembly
F0T03_07330	COG3691	Protein conserved in bacteria
F0T03_07335	COG0183	Belongs to the thiolase family
F0T03_07340	COG1024	Enoyl-CoA hydratase
F0T03_07340	COG1250	3-hydroxyacyl-CoA dehydrogenase
F0T03_07345	COG2062	phosphohistidine phosphatase, SixA
F0T03_07350	COG2840	Smr protein MutS2
F0T03_07355	COG2890	protein-(glutamine-N5) methyltransferase activity
F0T03_07360	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
F0T03_07365	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
F0T03_07370	COG0730	response to heat
F0T03_07375	COG3101	peptidyl-lysine hydroxylation
F0T03_07385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0T03_07385	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
F0T03_07390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0T03_07395	COG0745	RESPONSE REGULATOR receiver
F0T03_07395	COG3706	GGDEF domain
F0T03_07400	COG1794	racemase activity, acting on amino acids and derivatives
F0T03_07410	COG1447	Phosphotransferase system cellobiose-specific component IIA
F0T03_07415	COG2723	6-phospho-beta-galactosidase activity
F0T03_07420	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
F0T03_07430	COG1609	Transcriptional regulator
F0T03_07440	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F0T03_07455	COG4232	protein-disulfide reductase activity
F0T03_07465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T03_07470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0T03_07480	COG0697	spore germination
F0T03_07490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0T03_07495	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F0T03_07505	COG0586	Pfam SNARE associated Golgi protein
F0T03_07510	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
F0T03_07515	COG0285	dihydrofolate synthase activity
F0T03_07520	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
F0T03_07525	COG1286	toxin biosynthetic process
F0T03_07530	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
F0T03_07535	COG0163	prenyltransferase activity
F0T03_07540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0T03_07545	COG4215	(ABC) transporter
F0T03_07550	COG4160	amino acid transport
F0T03_07555	COG4598	ABC transporter
F0T03_07560	COG1090	epimerase
F0T03_07570	COG0622	Phosphoesterase
F0T03_07575	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
F0T03_07580	COG3037	sugar-specific permease SgaT UlaA
F0T03_07590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0T03_07595	COG1609	Transcriptional regulator
F0T03_07600	COG0280	phosphate acetyltransferase
F0T03_07600	COG0857	belongs to the CobB CobQ family
F0T03_07610	COG3092	negative regulation of chromosome organization
F0T03_07615	COG3013	Belongs to the UPF0304 family
F0T03_07620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0T03_07630	COG0471	metal ion transport
F0T03_07630	COG0490	domain, Protein
F0T03_07635	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F0T03_07640	COG0436	Aminotransferase
F0T03_07645	COG0583	DNA-binding transcription factor activity
F0T03_07650	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T03_07655	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T03_07660	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T03_07660	COG0649	NAD binding
F0T03_07665	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
F0T03_07670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F0T03_07675	COG1034	ATP synthesis coupled electron transport
F0T03_07680	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
F0T03_07685	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T03_07690	COG0839	Belongs to the complex I subunit 6 family
F0T03_07695	COG0713	ATP synthesis coupled electron transport
F0T03_07700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F0T03_07705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T03_07710	COG1007	ATP synthesis coupled electron transport
F0T03_07740	COG3265	gluconokinase activity
F0T03_07745	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_07750	COG1609	Transcriptional regulator
F0T03_07755	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0T03_07765	COG4702	Belongs to the UPF0303 family
F0T03_07770	COG0129	dihydroxy-acid dehydratase activity
F0T03_07775	COG4575	ribosome binding
F0T03_07780	COG1169	isochorismate synthase
F0T03_07785	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
F0T03_07790	COG0596	Alpha beta hydrolase
F0T03_07795	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
F0T03_07800	COG1441	menaquinone biosynthetic process
F0T03_07820	COG0814	amino acid
F0T03_07830	COG4574	serine-type endopeptidase inhibitor activity
F0T03_07835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0T03_07845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F0T03_07850	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F0T03_07860	COG0784	Response regulator, receiver
F0T03_07860	COG2205	protein histidine kinase activity
F0T03_07870	COG2198	Histidine kinase
F0T03_07870	COG0642	Histidine kinase
F0T03_07875	COG2223	nitrite transmembrane transporter activity
F0T03_07880	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
F0T03_07895	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F0T03_07940	COG1263	PTS System
F0T03_07940	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0T03_07940	COG2190	(PTS) system
F0T03_07945	COG2723	6-phospho-beta-galactosidase activity
F0T03_07950	COG3338	carbonate dehydratase activity
F0T03_07995	COG3082	Protein of unknown function (DUF1414)
F0T03_08000	COG3081	Nucleoid-associated protein
F0T03_08010	COG1061	Type III restriction enzyme res subunit
F0T03_08015	COG1187	pseudouridine synthase activity
F0T03_08020	COG2814	Major facilitator Superfamily
F0T03_08030	COG4172	Belongs to the ABC transporter superfamily
F0T03_08035	COG4239	(ABC) transporter, permease
F0T03_08040	COG4174	ABC transporter (Permease)
F0T03_08045	COG4166	transmembrane transport
F0T03_08050	COG2200	EAL domain
F0T03_08060	COG0791	NLP P60 protein
F0T03_08065	COG0671	phosphoesterase, PA-phosphatase related
F0T03_08070	COG0523	cobalamin synthesis protein
F0T03_08080	COG2186	Transcriptional regulator
F0T03_08085	COG0246	Mannitol dehydrogenase
F0T03_08090	COG1312	Catalyzes the dehydration of D-mannonate
F0T03_08095	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
F0T03_08110	COG0243	molybdopterin cofactor binding
F0T03_08115	COG3005	denitrification pathway
F0T03_08130	COG1105	Belongs to the carbohydrate kinase PfkB family
F0T03_08135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F0T03_08135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F0T03_08135	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F0T03_08140	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
F0T03_08145	COG2855	membrane
F0T03_08160	COG0583	DNA-binding transcription factor activity
F0T03_08165	COG0833	amino acid
F0T03_08170	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0T03_08180	COG4771	TonB-dependent receptor
F0T03_08185	COG0625	glutathione transferase activity
F0T03_08210	COG2011	ABC-type metal ion transport system permease component
F0T03_08215	COG0626	cystathionine gamma-synthase activity
F0T03_08225	COG1686	Belongs to the peptidase S11 family
F0T03_08230	COG1760	l-serine dehydratase
F0T03_08235	COG0814	amino acid
F0T03_08240	COG1349	DNA-binding transcription factor activity
F0T03_08245	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
F0T03_08250	COG0671	phosphoesterase, PA-phosphatase related
F0T03_08260	COG0569	domain protein
F0T03_08260	COG2985	domain, Protein
F0T03_08265	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F0T03_08280	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
F0T03_08285	COG3842	ATPase activity
F0T03_08290	COG1176	ABC-type spermidine putrescine transport system, permease component I
F0T03_08295	COG1177	transmembrane transport
F0T03_08305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F0T03_08310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0T03_08315	COG4160	amino acid transport
F0T03_08320	COG4215	(ABC) transporter
F0T03_08325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0T03_08330	COG1126	abc transporter atp-binding protein
F0T03_08345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0T03_08350	COG0702	epimerase
F0T03_08355	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
F0T03_08360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
F0T03_08365	COG0028	Belongs to the TPP enzyme family
F0T03_08370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0T03_08375	COG1151	hydroxylamine reductase activity
F0T03_08380	COG2431	L-lysine efflux transmembrane transporter activity
F0T03_08385	COG3593	DNA synthesis involved in DNA repair
F0T03_08390	COG2990	Protein conserved in bacteria
F0T03_08395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_08405	COG1278	Cold shock
F0T03_08410	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F0T03_08415	COG0542	response to heat
F0T03_08420	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
F0T03_08425	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F0T03_08430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
F0T03_08440	COG0492	ferredoxin-NADP+ reductase activity
F0T03_08450	COG3107	peptidoglycan biosynthetic process
F0T03_08450	COG1674	ftsk spoiiie
F0T03_08455	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F0T03_08460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F0T03_08470	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
F0T03_08475	COG2814	Major facilitator Superfamily
F0T03_08480	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F0T03_08485	COG1882	Formate acetyltransferase
F0T03_08490	COG2116	formate transmembrane transporter activity
F0T03_08495	COG1944	ATP diphosphatase activity
F0T03_08500	COG0252	asparaginase activity
F0T03_08510	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F0T03_08515	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F0T03_08520	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
F0T03_08525	COG0539	negative regulation of cytoplasmic translation
F0T03_08530	COG0776	regulation of translation
F0T03_08535	COG0658	competence protein
F0T03_08535	COG2333	competence protein COMEC
F0T03_08545	COG1663	tetraacyldisaccharide 4'-kinase activity
F0T03_08550	COG5383	Protein conserved in bacteria
F0T03_08560	COG1278	Cold shock
F0T03_08565	COG2835	tetraacyldisaccharide 4'-kinase activity
F0T03_08575	COG3173	Aminoglycoside phosphotransferase
F0T03_08580	COG1434	Gram-negative-bacterium-type cell wall biogenesis
F0T03_08585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F0T03_08590	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
F0T03_08595	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
F0T03_08600	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
F0T03_08605	COG2989	Protein conserved in bacteria
F0T03_08610	COG3108	Peptidase M15
F0T03_08615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F0T03_08620	COG2200	EAL domain
F0T03_08625	COG1448	Aminotransferase
F0T03_08640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
F0T03_08645	COG0308	aminopeptidase N
F0T03_08650	COG0167	dihydroorotate dehydrogenase activity
F0T03_08660	COG0633	Ferredoxin
F0T03_08660	COG3217	Mosc domain protein beta barrel domain protein
F0T03_08665	COG0116	Belongs to the methyltransferase superfamily
F0T03_08665	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F0T03_08670	COG0488	(ABC) transporter
F0T03_08675	COG2995	paraquat-inducible protein a
F0T03_08680	COG3008	intermembrane lipid transfer
F0T03_08680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F0T03_08685	COG3009	Protein conserved in bacteria
F0T03_08690	COG3130	regulation of translation
F0T03_08695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0T03_08705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0T03_08710	COG1067	ATP-dependent peptidase activity
F0T03_08715	COG3120	sequence-specific DNA binding
F0T03_08720	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F0T03_08720	COG2885	chlorophyll binding
F0T03_08725	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
F0T03_08730	COG3070	regulator of competence-specific genes
F0T03_08735	COG1289	transmembrane transporter activity
F0T03_08740	COG3304	Inner membrane component domain
F0T03_08745	COG0210	DNA helicase
F0T03_08755	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
F0T03_08760	COG1832	CoA-binding protein
F0T03_08765	COG3785	DNA binding
F0T03_08770	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
F0T03_08785	COG1254	Belongs to the acylphosphatase family
F0T03_08790	COG2920	part of a sulfur-relay system
F0T03_08805	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
F0T03_08810	COG0437	4 iron, 4 sulfur cluster binding
F0T03_08815	COG3301	Polysulphide reductase, NrfD
F0T03_08820	COG1138	Cytochrome C-type biogenesis protein
F0T03_08825	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F0T03_08830	COG4235	cytochrome complex assembly
F0T03_08830	COG3088	subunit of a heme lyase
F0T03_08840	COG2771	luxR family
F0T03_08845	COG3916	Acyl-homoserine-lactone synthase
F0T03_08855	COG3263	regulation of cellular component size
F0T03_08870	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
F0T03_08875	COG2943	transferase activity, transferring hexosyl groups
F0T03_08880	COG5645	(Lipo)protein
F0T03_08895	COG3104	oligopeptide transport
F0T03_08900	COG2814	Major facilitator Superfamily
F0T03_08905	COG2259	Doxx family
F0T03_08910	COG1560	Kdo2-lipid A biosynthetic process
F0T03_08945	COG0628	permease
F0T03_08975	COG0418	dihydroorotase activity
F0T03_08980	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F0T03_08985	COG1530	ribonuclease E activity
F0T03_08990	COG0564	pseudouridine synthase activity
F0T03_09000	COG1399	metal-binding, possibly nucleic acid-binding protein
F0T03_09005	COG0333	Belongs to the bacterial ribosomal protein bL32 family
F0T03_09010	COG0416	fatty acid biosynthetic process
F0T03_09020	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F0T03_09025	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_09035	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
F0T03_09040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F0T03_09045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F0T03_09050	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
F0T03_09055	COG0470	DNA polymerase III
F0T03_09060	COG0084	hydrolase, TatD family'
F0T03_09065	COG1263	PTS System
F0T03_09065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0T03_09075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0T03_09080	COG0537	adenosine 5'-monophosphoramidase activity
F0T03_09085	COG5633	Lipoprotein
F0T03_09090	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
F0T03_09095	COG0510	thiamine kinase activity
F0T03_09105	COG3150	esterase
F0T03_09110	COG1252	NADH dehydrogenase
F0T03_09115	COG3134	Outer membrane lipoprotein
F0T03_09120	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F0T03_09125	COG4591	ABC-type transport system involved in lipoprotein release permease component
F0T03_09135	COG4591	ABC-type transport system involved in lipoprotein release permease component
F0T03_09140	COG1940	carbohydrate kinase activity
F0T03_09145	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F0T03_09155	COG2850	peptidyl-arginine hydroxylation
F0T03_09165	COG0745	RESPONSE REGULATOR receiver
F0T03_09175	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F0T03_09180	COG2915	High frequency lysogenization protein hflD homolog
F0T03_09185	COG0482	sulfurtransferase activity
F0T03_09195	COG1187	pseudouridine synthase activity
F0T03_09200	COG0538	isocitrate dehydrogenase activity
F0T03_09205	COG0582	viral genome integration into host DNA
F0T03_09225	COG2814	Major facilitator Superfamily
F0T03_09245	COG2826	transposase and inactivated derivatives, IS30 family
F0T03_09290	COG0538	isocitrate dehydrogenase activity
F0T03_09325	COG0840	transmembrane signaling receptor activity
F0T03_09335	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F0T03_09345	COG2873	o-acetylhomoserine
F0T03_09350	COG0702	epimerase
F0T03_09355	COG1733	regulation of RNA biosynthetic process
F0T03_09365	COG0697	spore germination
F0T03_09375	COG3755	Protein conserved in bacteria
F0T03_09390	COG5001	Diguanylate cyclase
F0T03_09390	COG4251	negative regulation of phosphorylation
F0T03_09390	COG3706	GGDEF domain
F0T03_09390	COG2203	Gaf domain
F0T03_09400	COG1132	(ABC) transporter
F0T03_09420	COG2207	Transcriptional regulator
F0T03_09455	COG1113	amino acid transport
F0T03_09470	COG1278	Cold shock
F0T03_09480	COG0768	penicillin binding
F0T03_09485	COG2226	methyltransferase
F0T03_09495	COG5002	protein histidine kinase activity
F0T03_09495	COG3447	MASE1 domain protein
F0T03_09495	COG5001	Diguanylate cyclase
F0T03_09505	COG1971	Probably functions as a manganese efflux pump
F0T03_09510	COG4811	Protein of unknown function (DUF986)
F0T03_09515	COG3716	PTS system mannose fructose sorbose family IID component
F0T03_09520	COG3715	PTS system
F0T03_09525	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0T03_09525	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0T03_09530	COG1253	flavin adenine dinucleotide binding
F0T03_09540	COG1760	l-serine dehydratase
F0T03_09545	COG0494	nUDIX hydrolase
F0T03_09555	COG3140	Belongs to the UPF0181 family
F0T03_09560	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
F0T03_09565	COG0513	Belongs to the DEAD box helicase family
F0T03_09570	COG3141	response to X-ray
F0T03_09585	COG1770	oligopeptidase
F0T03_09590	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F0T03_09605	COG1528	Iron-storage protein
F0T03_09610	COG2372	response to copper ion
F0T03_09615	COG1276	copper resistance
F0T03_09685	COG0668	transmembrane transport
F0T03_09695	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
F0T03_09700	COG0589	response to stress
F0T03_09715	COG1187	pseudouridine synthase activity
F0T03_09735	COG0625	glutathione transferase activity
F0T03_09755	COG3706	GGDEF domain
F0T03_09755	COG5001	Diguanylate cyclase
F0T03_09755	COG2203	Gaf domain
F0T03_09755	COG4251	negative regulation of phosphorylation
F0T03_09800	COG3008	intermembrane lipid transfer
F0T03_09805	COG2995	paraquat-inducible protein a
F0T03_09810	COG1956	GAF domain-containing protein
F0T03_09820	COG0793	Belongs to the peptidase S41A family
F0T03_09825	COG0501	Belongs to the peptidase M48B family
F0T03_09830	COG2814	Major facilitator Superfamily
F0T03_09835	COG0823	Involved in the tonB-independent uptake of proteins
F0T03_09845	COG3023	N-Acetylmuramoyl-L-alanine amidase
F0T03_09855	COG1988	membrane-bound metal-dependent
F0T03_09865	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F0T03_09870	COG1653	transport
F0T03_09875	COG3842	ATPase activity
F0T03_09880	COG0395	ABC-type sugar transport system, permease component
F0T03_09885	COG1175	transmembrane transport
F0T03_09895	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_09900	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
F0T03_09905	COG1917	Cupin 2, conserved barrel domain protein
F0T03_09910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0T03_09920	COG0583	DNA-binding transcription factor activity
F0T03_09925	COG0427	acetyl-CoA hydrolase
F0T03_09930	COG1024	Enoyl-CoA hydratase
F0T03_09935	COG1703	isobutyryl-CoA mutase activity
F0T03_09940	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0T03_09940	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0T03_09950	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F0T03_09955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F0T03_09960	COG1121	(ABC) transporter
F0T03_09965	COG0803	Belongs to the bacterial solute-binding protein 9 family
F0T03_10000	COG1811	Na channel or pump
F0T03_10010	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
F0T03_10015	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F0T03_10020	COG0291	Belongs to the bacterial ribosomal protein bL35 family
F0T03_10025	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
F0T03_10045	COG0776	regulation of translation
F0T03_10055	COG4139	cobalamin transport
F0T03_10060	COG0386	Belongs to the glutathione peroxidase family
F0T03_10065	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
F0T03_10070	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F0T03_10075	COG0463	Glycosyl transferase, family 2
F0T03_10080	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F0T03_10080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0T03_10085	COG0726	polysaccharide deacetylase
F0T03_10090	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
F0T03_10095	COG2076	Multidrug Resistance protein
F0T03_10100	COG2076	Multidrug Resistance protein
F0T03_10105	COG0791	NLP P60 protein
F0T03_10110	COG0095	Lipoate-protein ligase
F0T03_10120	COG4558	Periplasmic binding protein
F0T03_10125	COG3720	iron ion transport
F0T03_10145	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
F0T03_10150	COG0574	Belongs to the PEP-utilizing enzyme family
F0T03_10150	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F0T03_10160	COG0628	permease
F0T03_10165	COG0277	FAD linked oxidase domain protein
F0T03_10165	COG0247	lactate metabolic process
F0T03_10170	COG2050	protein possibly involved in aromatic compounds catabolism
F0T03_10180	COG0316	Belongs to the HesB IscA family
F0T03_10185	COG0719	Fe-S assembly protein
F0T03_10190	COG0396	ATPase activity
F0T03_10195	COG0719	Fe-S assembly protein
F0T03_10205	COG2166	iron-sulfur cluster assembly
F0T03_10210	COG1388	LysM domain
F0T03_10210	COG1376	ErfK ybiS ycfS ynhG family protein
F0T03_10215	COG4238	major outer membrane lipoprotein
F0T03_10240	COG0534	Mate efflux family protein
F0T03_10245	COG0307	riboflavin synthase, alpha
F0T03_10250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F0T03_10255	COG2814	Major facilitator Superfamily
F0T03_10260	COG0583	DNA-binding transcription factor activity
F0T03_10265	COG1609	Transcriptional regulator
F0T03_10275	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F0T03_10280	COG0791	NLP P60 protein
F0T03_10290	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F0T03_10295	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F0T03_10300	COG0346	lactoylglutathione lyase activity
F0T03_10310	COG1902	pentaerythritol trinitrate reductase activity
F0T03_10315	COG1309	transcriptional regulator
F0T03_10320	COG2194	sulfuric ester hydrolase activity
F0T03_10325	COG3313	Fe-S protein
F0T03_10330	COG4989	oxidoreductase activity
F0T03_10340	COG1566	PFAM secretion protein HlyD family protein
F0T03_10350	COG1846	Transcriptional regulator
F0T03_10355	COG3133	Outer membrane lipoprotein
F0T03_10360	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F0T03_10365	COG3895	Periplasmic Protein
F0T03_10375	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F0T03_10385	COG0625	glutathione transferase activity
F0T03_10405	COG3104	oligopeptide transport
F0T03_10415	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0T03_10415	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F0T03_10425	COG4172	Belongs to the ABC transporter superfamily
F0T03_10435	COG4171	peptide transport system, permease
F0T03_10440	COG4168	peptide transport system, permease
F0T03_10445	COG4166	transmembrane transport
F0T03_10460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
F0T03_10465	COG1842	Phage shock protein A
F0T03_10475	COG1983	PspC domain protein
F0T03_10485	COG3106	COG3106 Predicted ATPase
F0T03_10490	COG3768	UPF0283 membrane protein
F0T03_10510	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
F0T03_10515	COG4948	Mandelate Racemase Muconate Lactonizing
F0T03_10520	COG2866	Carboxypeptidase
F0T03_10525	COG4166	transmembrane transport
F0T03_10540	COG0598	Magnesium transport protein CorA
F0T03_10545	COG0037	tRNA processing
F0T03_10550	COG0823	Involved in the tonB-independent uptake of proteins
F0T03_10560	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T03_10560	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
F0T03_10560	COG1013	pyruvate-flavodoxin oxidoreductase activity
F0T03_10560	COG0674	pyruvate-flavodoxin oxidoreductase activity
F0T03_10570	COG1285	pathogenesis
F0T03_10580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F0T03_10585	COG2911	Protein conserved in bacteria
F0T03_10595	COG3784	Protein of unknown function (DUF1318)
F0T03_10600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F0T03_10610	COG1643	Atp-dependent helicase
F0T03_10615	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
F0T03_10625	COG3591	Belongs to the peptidase S1B family
F0T03_10635	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
F0T03_10640	COG2205	protein histidine kinase activity
F0T03_10645	COG0745	RESPONSE REGULATOR receiver
F0T03_10655	COG0531	amino acid
F0T03_10665	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F0T03_10670	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F0T03_10675	COG0589	response to stress
F0T03_10680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F0T03_10685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F0T03_10700	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
F0T03_10705	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_10715	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0T03_10720	COG0738	Major facilitator superfamily
F0T03_10735	COG0583	DNA-binding transcription factor activity
F0T03_10745	COG1011	Hydrolase
F0T03_10750	COG0440	acetolactate synthase activity
F0T03_10755	COG0028	Belongs to the TPP enzyme family
F0T03_10770	COG3023	N-Acetylmuramoyl-L-alanine amidase
F0T03_10790	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F0T03_10805	COG4215	(ABC) transporter
F0T03_10815	COG1522	sequence-specific DNA binding
F0T03_10830	COG1773	rubredoxin
F0T03_10830	COG0426	domain, Protein
F0T03_10835	COG3604	Transcriptional regulator
F0T03_10840	COG0625	glutathione transferase activity
F0T03_10860	COG0477	Major facilitator Superfamily
F0T03_10865	COG4221	oxidoreductase activity
F0T03_10870	COG1742	UPF0060 membrane protein
F0T03_10890	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F0T03_10900	COG1940	carbohydrate kinase activity
F0T03_10905	COG0583	DNA-binding transcription factor activity
F0T03_10910	COG2814	Major facilitator Superfamily
F0T03_10930	COG0114	fumarate hydratase activity
F0T03_10940	COG5339	Protein conserved in bacteria
F0T03_10945	COG1609	Transcriptional regulator
F0T03_10950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0T03_10950	COG1263	PTS System
F0T03_10955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F0T03_10960	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F0T03_10965	COG0385	Bile acid
F0T03_10970	COG0673	inositol 2-dehydrogenase activity
F0T03_10980	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_10990	COG1879	ABC-type sugar transport system periplasmic component
F0T03_11000	COG2160	L-arabinose isomerase activity
F0T03_11015	COG2274	protein secretion by the type I secretion system
F0T03_11020	COG2759	Belongs to the formate--tetrahydrofolate ligase family
F0T03_11030	COG4657	Part of a membrane complex involved in electron transport
F0T03_11040	COG4656	Part of a membrane complex involved in electron transport
F0T03_11045	COG2207	Transcriptional regulator
F0T03_11045	COG3708	Transcriptional regulator
F0T03_11050	COG4658	electron transport chain
F0T03_11055	COG4659	FMN binding
F0T03_11065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F0T03_11085	COG0243	molybdopterin cofactor binding
F0T03_11090	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
F0T03_11095	COG1966	Carbon starvation protein
F0T03_11100	COG2879	small protein
F0T03_11105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F0T03_11110	COG1349	DNA-binding transcription factor activity
F0T03_11130	COG0023	Translation Initiation Factor
F0T03_11135	COG0284	orotidine-5'-phosphate decarboxylase activity
F0T03_11145	COG3135	benzoate transporter
F0T03_11150	COG1396	sequence-specific DNA binding
F0T03_11160	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
F0T03_11165	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
F0T03_11170	COG0671	phosphoesterase, PA-phosphatase related
F0T03_11175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F0T03_11180	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F0T03_11195	COG0583	DNA-binding transcription factor activity
F0T03_11200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F0T03_11210	COG0616	signal peptide processing
F0T03_11215	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_11220	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
F0T03_11225	COG1187	pseudouridine synthase activity
F0T03_11230	COG2197	response regulator
F0T03_11245	COG1388	LysM domain
F0T03_11245	COG4932	domain protein
F0T03_11245	COG2373	Large extracellular alpha-helical protein
F0T03_11265	COG0009	L-threonylcarbamoyladenylate synthase
F0T03_11270	COG0613	PHP domain protein
F0T03_11285	COG0512	Glutamine amidotransferase of anthranilate synthase
F0T03_11295	COG0134	indole-3-glycerol-phosphate synthase activity
F0T03_11295	COG0135	phosphoribosylanthranilate isomerase activity
F0T03_11300	COG0133	tryptophan synthase activity
F0T03_11305	COG0159	tryptophan synthase activity
F0T03_11315	COG3047	cAMP biosynthetic process
F0T03_11335	COG2917	probably involved in intracellular septation
F0T03_11340	COG1607	acyl-coa hydrolase
F0T03_11345	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
F0T03_11350	COG2350	Protein conserved in bacteria
F0T03_11375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0T03_11390	COG0444	Belongs to the ABC transporter superfamily
F0T03_11395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0T03_11410	COG2095	MarC family integral membrane protein
F0T03_11420	COG1454	alcohol dehydrogenase
F0T03_11420	COG1012	belongs to the aldehyde dehydrogenase family
F0T03_11425	COG1435	thymidine kinase activity
F0T03_11435	COG2916	Histone family protein nucleoid-structuring protein H-NS
F0T03_11445	COG0745	RESPONSE REGULATOR receiver
F0T03_11450	COG1752	Esterase of the alpha-beta hydrolase superfamily
F0T03_11460	COG3012	SEC-C Motif Domain Protein
F0T03_11465	COG0788	formyltetrahydrofolate deformylase activity
F0T03_11480	COG0583	DNA-binding transcription factor activity
F0T03_11485	COG0708	Exodeoxyribonuclease III
F0T03_11490	COG0494	nUDIX hydrolase
F0T03_11500	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F0T03_11510	COG0778	Nitroreductase
F0T03_11515	COG0616	signal peptide processing
F0T03_11520	COG0252	asparaginase activity
F0T03_11530	COG3139	Protein of unknown function (DUF1315)
F0T03_11550	COG3713	MltA-interacting MipA family protein
F0T03_11560	COG2766	serine protein kinase
F0T03_11565	COG2718	Belongs to the UPF0229 family
F0T03_11580	COG0583	DNA-binding transcription factor activity
F0T03_11590	COG2202	Pas domain
F0T03_11590	COG2199	diguanylate cyclase activity
F0T03_11590	COG2200	EAL domain
F0T03_11595	COG2814	Major facilitator Superfamily
F0T03_11600	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F0T03_11605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F0T03_11610	COG2719	SpoVR family
F0T03_11615	COG2186	Transcriptional regulator
F0T03_11620	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F0T03_11625	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
F0T03_11635	COG2983	Belongs to the UPF0260 family
F0T03_11640	COG0179	Fumarylacetoacetate (FAA) hydrolase
F0T03_11645	COG2951	lytic endotransglycosylase activity
F0T03_11650	COG3100	YcgL domain-containing protein
F0T03_11660	COG0850	regulation of cytokinetic process
F0T03_11665	COG2894	cell division
F0T03_11670	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
F0T03_11675	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
F0T03_11680	COG0318	PFAM AMP-dependent synthetase and ligase
F0T03_11685	COG3065	identical protein binding
F0T03_11695	COG1199	ATP-dependent helicase activity
F0T03_11700	COG0251	oxidation-reduction process
F0T03_11705	COG2076	Multidrug Resistance protein
F0T03_11710	COG2076	Multidrug Resistance protein
F0T03_11715	COG0800	Aldolase
F0T03_11720	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
F0T03_11730	COG1737	Transcriptional regulator
F0T03_11735	COG0469	pyruvate kinase activity
F0T03_11740	COG1560	Kdo2-lipid A biosynthetic process
F0T03_11745	COG0739	heme binding
F0T03_11750	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
F0T03_11755	COG1121	(ABC) transporter
F0T03_11760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F0T03_11765	COG3104	oligopeptide transport
F0T03_11770	COG2255	four-way junction helicase activity
F0T03_11775	COG0632	four-way junction helicase activity
F0T03_11785	COG0217	transcriptional regulatory protein
F0T03_11790	COG0494	nUDIX hydrolase
F0T03_11795	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
F0T03_11805	COG1335	isochorismatase
F0T03_11810	COG1801	Protein of unknown function DUF72
F0T03_11815	COG3788	relative of glutathione S-transferase, MAPEG superfamily
F0T03_11825	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F0T03_11830	COG3142	Participates in the control of copper homeostasis
F0T03_11835	COG3102	Protein conserved in bacteria
F0T03_11840	COG0018	arginyl-trna synthetase
F0T03_11845	COG0728	peptidoglycan biosynthetic process
F0T03_11850	COG0673	inositol 2-dehydrogenase activity
F0T03_11860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0T03_11865	COG0477	Major facilitator Superfamily
F0T03_11875	COG3381	protein complex oligomerization
F0T03_11880	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
F0T03_11885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0T03_11905	COG3706	GGDEF domain
F0T03_11910	COG0659	secondary active sulfate transmembrane transporter activity
F0T03_11915	COG2877	3-deoxy-8-phosphooctulonate synthase activity
F0T03_11920	COG2912	Transglutaminase-like superfamily
F0T03_11925	COG3094	Invasion gene expression up-regulator, SirB
F0T03_11930	COG2890	protein-(glutamine-N5) methyltransferase activity
F0T03_11935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
F0T03_11940	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
F0T03_11945	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
F0T03_11955	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F0T03_11975	COG0193	aminoacyl-tRNA hydrolase activity
F0T03_11985	COG0012	GTP binding
F0T03_11990	COG0582	viral genome integration into host DNA
F0T03_11995	COG2267	carboxylic ester hydrolase activity
F0T03_12000	COG0583	DNA-binding transcription factor activity
F0T03_12010	COG0582	viral genome integration into host DNA
F0T03_12090	COG2003	Belongs to the UPF0758 family
F0T03_12115	COG3423	Transcriptional regulator
F0T03_12155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_12160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0T03_12195	COG0640	Transcriptional regulator
F0T03_12200	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
F0T03_12205	COG1393	Belongs to the ArsC family
F0T03_12215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0T03_12220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_12225	COG0745	RESPONSE REGULATOR receiver
F0T03_12230	COG2205	protein histidine kinase activity
F0T03_12240	COG1349	DNA-binding transcription factor activity
F0T03_12250	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0T03_12260	COG3716	PTS system mannose fructose sorbose family IID component
F0T03_12265	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0T03_12270	COG2222	sugar isomerase
F0T03_12280	COG4942	peptidase
F0T03_12290	COG3443	Belongs to the bacterial solute-binding protein 9 family
F0T03_12295	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_12300	COG1129	ABC transporter
F0T03_12315	COG0402	S-adenosylhomocysteine deaminase activity
F0T03_12325	COG1228	amidohydrolase
F0T03_12340	COG2988	succinylglutamate desuccinylase activity
F0T03_12345	COG3724	N-succinylarginine dihydrolase activity
F0T03_12355	COG3138	arginine N-succinyltransferase
F0T03_12360	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F0T03_12370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0T03_12375	COG1271	oxidase subunit
F0T03_12380	COG1294	oxidase, subunit
F0T03_12390	COG3850	Histidine kinase
F0T03_12395	COG0583	DNA-binding transcription factor activity
F0T03_12400	COG2814	Major facilitator Superfamily
F0T03_12410	COG0387	Pfam Sodium calcium exchanger
F0T03_12415	COG1702	phosphate starvation-inducible protein PhoH
F0T03_12430	COG3658	cytochrome
F0T03_12435	COG1215	transferase activity, transferring glycosyl groups
F0T03_12440	COG0726	polysaccharide deacetylase
F0T03_12440	COG1649	PFAM Uncharacterised BCR, COG1649
F0T03_12445	COG0457	Tetratricopeptide repeat
F0T03_12450	COG0006	proline dipeptidase activity
F0T03_12460	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
F0T03_12485	COG0577	efflux transmembrane transporter activity
F0T03_12485	COG1136	(ABC) transporter
F0T03_12495	COG1136	(ABC) transporter
F0T03_12495	COG0577	efflux transmembrane transporter activity
F0T03_12510	COG0672	)-iron permease
F0T03_12525	COG2066	Belongs to the glutaminase family
F0T03_12530	COG3622	Belongs to the hyi family
F0T03_12535	COG0235	Class ii aldolase
F0T03_12540	COG3395	kinase activity
F0T03_12545	COG1349	DNA-binding transcription factor activity
F0T03_12550	COG3290	protein histidine kinase activity
F0T03_12555	COG4565	transcriptional regulatory protein
F0T03_12560	COG3493	citrate carrier protein
F0T03_12580	COG0346	lactoylglutathione lyase activity
F0T03_12590	COG2223	nitrite transmembrane transporter activity
F0T03_12595	COG0561	phosphatase activity
F0T03_12600	COG0488	(ABC) transporter
F0T03_12610	COG3122	Protein conserved in bacteria
F0T03_12680	COG0251	oxidation-reduction process
F0T03_12690	COG3772	lysozyme
F0T03_12725	COG2801	Transposase and inactivated derivatives
F0T03_12740	COG2826	transposase and inactivated derivatives, IS30 family
F0T03_12755	COG1403	HNH endonuclease
F0T03_12820	COG5532	Uncharacterized conserved protein (DUF2303)
F0T03_12825	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
F0T03_12875	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F0T03_12880	COG0322	excinuclease ABC activity
F0T03_12885	COG2197	response regulator
F0T03_12895	COG3136	membrane protein required for alginate biosynthesis
F0T03_12920	COG2226	methyltransferase
F0T03_12940	COG1113	amino acid transport
F0T03_12950	COG1881	PFAM PEBP family protein
F0T03_12955	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
F0T03_12965	COG0655	NAD(P)H dehydrogenase (quinone) activity
F0T03_12990	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F0T03_12990	COG0506	proline dehydrogenase activity
F0T03_12990	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F0T03_13020	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F0T03_13030	COG1191	sigma factor activity
F0T03_13060	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
F0T03_13075	COG1677	Flagellar hook-basal body complex protein FliE
F0T03_13085	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
F0T03_13090	COG1317	bacterial-type flagellum organization
F0T03_13095	COG1157	protein secretion by the type III secretion system
F0T03_13100	COG2882	bacterial-type flagellum organization
F0T03_13110	COG1580	Controls the rotational direction of flagella during chemotaxis
F0T03_13130	COG1338	Plays a role in the flagellum-specific transport system
F0T03_13140	COG1684	flagellar biosynthetic protein fliR
F0T03_13150	COG1256	bacterial-type flagellum assembly
F0T03_13170	COG4786	Flagellar basal body rod
F0T03_13180	COG1749	Flagellar hook protein flgE
F0T03_13185	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
F0T03_13190	COG1558	bacterial-type flagellum-dependent cell motility
F0T03_13195	COG1815	bacterial-type flagellum-dependent cell motility
F0T03_13205	COG2747	anti-sigma28 factor FlgM
F0T03_13210	COG3418	PFAM FlgN family protein
F0T03_13220	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F0T03_13225	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
F0T03_13230	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
F0T03_13235	COG0745	RESPONSE REGULATOR receiver
F0T03_13245	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
F0T03_13250	COG0840	transmembrane signaling receptor activity
F0T03_13255	COG0840	transmembrane signaling receptor activity
F0T03_13260	COG0835	chemotaxis
F0T03_13265	COG0643	Histidine kinase
F0T03_13265	COG2198	Histidine kinase
F0T03_13270	COG1360	Flagellar Motor Protein
F0T03_13290	COG0589	response to stress
F0T03_13295	COG2130	NADP-dependent
F0T03_13305	COG1285	pathogenesis
F0T03_13310	COG0840	transmembrane signaling receptor activity
F0T03_13320	COG1278	Cold shock
F0T03_13325	COG1609	Transcriptional regulator
F0T03_13330	COG3250	beta-galactosidase activity
F0T03_13335	COG0604	alcohol dehydrogenase
F0T03_13335	COG3321	synthase
F0T03_13335	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_13365	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
F0T03_13375	COG0671	phosphoesterase, PA-phosphatase related
F0T03_13375	COG2453	phosphatase
F0T03_13380	COG2267	carboxylic ester hydrolase activity
F0T03_13390	COG4589	Belongs to the CDS family
F0T03_13395	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F0T03_13400	COG3121	Chaperone
F0T03_13415	COG3121	Chaperone
F0T03_13425	COG3121	Chaperone
F0T03_13450	COG3228	Belongs to the MtfA family
F0T03_13460	COG0582	viral genome integration into host DNA
F0T03_13470	COG1902	pentaerythritol trinitrate reductase activity
F0T03_13485	COG0583	DNA-binding transcription factor activity
F0T03_13490	COG0583	DNA-binding transcription factor activity
F0T03_13500	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_13515	COG0583	DNA-binding transcription factor activity
F0T03_13530	COG0300	oxidoreductase activity
F0T03_13560	COG2189	Belongs to the N(4) N(6)-methyltransferase family
F0T03_13570	COG2826	transposase and inactivated derivatives, IS30 family
F0T03_13580	COG5290	Psort location Cytoplasmic, score
F0T03_13585	COG3547	Transposase (IS116 IS110 IS902 family)
F0T03_13590	COG4227	nucleotidyltransferase activity
F0T03_13630	COG2315	Protein conserved in bacteria
F0T03_13635	COG2814	Major facilitator Superfamily
F0T03_13670	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
F0T03_13685	COG0471	metal ion transport
F0T03_13700	COG3051	citrate lyase alpha subunit
F0T03_13705	COG2301	Belongs to the HpcH HpaI aldolase family
F0T03_13710	COG3052	prosthetic group binding
F0T03_13715	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
F0T03_13720	COG3290	protein histidine kinase activity
F0T03_13725	COG4565	transcriptional regulatory protein
F0T03_13740	COG2271	Major facilitator Superfamily
F0T03_13745	COG1840	ABC-type Fe3 transport system, periplasmic component
F0T03_13755	COG3842	ATPase activity
F0T03_13770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0T03_13770	COG2205	protein histidine kinase activity
F0T03_13780	COG3121	Chaperone
F0T03_13785	COG3188	usher protein
F0T03_13795	COG3121	Chaperone
F0T03_13805	COG4221	oxidoreductase activity
F0T03_13820	COG0835	chemotaxis
F0T03_13820	COG0784	Response regulator, receiver
F0T03_13825	COG1349	DNA-binding transcription factor activity
F0T03_13830	COG0561	phosphatase activity
F0T03_13835	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F0T03_13845	COG0534	Mate efflux family protein
F0T03_13855	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F0T03_13865	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
F0T03_13875	COG1492	cobalamin metabolic process
F0T03_13925	COG2875	Belongs to the precorrin methyltransferase family
F0T03_13935	COG2241	protein methyltransferase activity
F0T03_13940	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
F0T03_13950	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
F0T03_13970	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
F0T03_14005	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
F0T03_14035	COG1012	belongs to the aldehyde dehydrogenase family
F0T03_14045	COG4656	Part of a membrane complex involved in electron transport
F0T03_14055	COG4810	utilization protein
F0T03_14065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F0T03_14075	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0T03_14090	COG1879	ABC-type sugar transport system periplasmic component
F0T03_14100	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_14115	COG1289	transmembrane transporter activity
F0T03_14120	COG1022	Amp-dependent synthetase and ligase
F0T03_14120	COG3320	Male sterility
F0T03_14125	COG2925	Exonuclease
F0T03_14130	COG0531	amino acid
F0T03_14140	COG0371	Dehydrogenase
F0T03_14145	COG1129	ABC transporter
F0T03_14150	COG1172	Belongs to the binding-protein-dependent transport system permease family
F0T03_14155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0T03_14165	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F0T03_14175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
F0T03_14180	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F0T03_14180	COG0131	Imidazoleglycerol-phosphate dehydratase
F0T03_14185	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F0T03_14190	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
F0T03_14195	COG0107	imidazoleglycerol-phosphate synthase activity
F0T03_14200	COG0140	phosphoribosyl-ATP diphosphatase activity
F0T03_14200	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F0T03_14205	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F0T03_14215	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F0T03_14220	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F0T03_14230	COG0438	transferase activity, transferring glycosyl groups
F0T03_14240	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
F0T03_14260	COG3039	Transposase
F0T03_14285	COG1253	flavin adenine dinucleotide binding
F0T03_14290	COG3069	C4-dicarboxylate transmembrane transporter activity
F0T03_14295	COG2982	Protein involved in outer membrane biogenesis
F0T03_14305	COG0572	uridine kinase
F0T03_14310	COG0489	protein tyrosine kinase activity
F0T03_14315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0T03_14315	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F0T03_14335	COG2814	Major facilitator Superfamily
F0T03_14340	COG1380	Effector of murein hydrolase LrgA
F0T03_14345	COG1346	cytolysis
F0T03_14355	COG0281	malic enzyme
F0T03_14360	COG2949	membrane
F0T03_14365	COG0298	carbon dioxide binding
F0T03_14370	COG0375	protein maturation
F0T03_14375	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F0T03_14380	COG0651	ATP synthesis coupled electron transport
F0T03_14385	COG0650	Formate hydrogenlyase subunit 4
F0T03_14390	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F0T03_14395	COG4237	Hydrogenase 4 membrane
F0T03_14400	COG0651	ATP synthesis coupled electron transport
F0T03_14405	COG3261	NADH dehydrogenase
F0T03_14405	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
F0T03_14410	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F0T03_14415	COG3260	NADH ubiquinone oxidoreductase 20
F0T03_14425	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F0T03_14430	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F0T03_14435	COG3383	formate dehydrogenase (NAD+) activity
F0T03_14440	COG3604	Transcriptional regulator
F0T03_14445	COG2116	formate transmembrane transporter activity
F0T03_14465	COG1609	Transcriptional regulator
F0T03_14470	COG2311	Membrane
F0T03_14475	COG0302	gtp cyclohydrolase
F0T03_14480	COG0477	Major facilitator Superfamily
F0T03_14485	COG0583	DNA-binding transcription factor activity
F0T03_14515	COG0577	efflux transmembrane transporter activity
F0T03_14515	COG1136	(ABC) transporter
F0T03_14525	COG0477	Major facilitator Superfamily
F0T03_14575	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
F0T03_14665	COG4695	Portal protein
F0T03_14730	COG4974	Belongs to the 'phage' integrase family
F0T03_14740	COG0303	'Molybdopterin
F0T03_14745	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F0T03_14750	COG3397	chitin binding
F0T03_14755	COG0488	(ABC) transporter
F0T03_14775	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F0T03_14795	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
F0T03_14810	COG4106	trans-aconitate 2-methyltransferase activity
F0T03_14815	COG0783	Belongs to the Dps family
F0T03_14820	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F0T03_14825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0T03_14830	COG0765	amino acid transport
F0T03_14835	COG1126	abc transporter atp-binding protein
F0T03_14845	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
F0T03_14860	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F0T03_14865	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F0T03_14885	COG0697	spore germination
F0T03_14900	COG1174	glycine betaine transport
F0T03_14905	COG1125	glycine betaine transport
F0T03_14910	COG1174	glycine betaine transport
F0T03_14915	COG1732	Glycine betaine
F0T03_14925	COG0673	inositol 2-dehydrogenase activity
F0T03_14930	COG2897	thiosulfate sulfurtransferase activity
F0T03_14935	COG0410	ABC transporter
F0T03_14940	COG0411	ABC transporter
F0T03_14950	COG0559	Belongs to the binding-protein-dependent transport system permease family
F0T03_14960	COG4807	Protein conserved in bacteria
F0T03_14975	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
F0T03_14985	COG2261	transglycosylase associated protein
F0T03_14995	COG1403	HNH endonuclease
F0T03_15005	COG0277	FAD linked oxidase domain protein
F0T03_15010	COG1686	Belongs to the peptidase S11 family
F0T03_15020	COG2239	Acts as a magnesium transporter
F0T03_15030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F0T03_15035	COG0513	Belongs to the DEAD box helicase family
F0T03_15040	COG1309	transcriptional regulator
F0T03_15045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_15050	COG1131	(ABC) transporter
F0T03_15055	COG0842	Transport permease protein
F0T03_15060	COG0842	Transport permease protein
F0T03_15065	COG0670	Belongs to the BI1 family
F0T03_15070	COG0314	molybdopterin synthase activity
F0T03_15075	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
F0T03_15080	COG0315	cyclic pyranopterin monophosphate synthase activity
F0T03_15085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F0T03_15090	COG0391	Required for morphogenesis under gluconeogenic growth conditions
F0T03_15095	COG4628	conserved protein (DUF2132)
F0T03_15100	COG0556	nucleotide-excision repair
F0T03_15110	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
F0T03_15115	COG2226	methyltransferase
F0T03_15120	COG0156	8-amino-7-oxononanoate synthase activity
F0T03_15125	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F0T03_15135	COG2706	6-phosphogluconolactonase activity
F0T03_15140	COG0561	phosphatase activity
F0T03_15150	COG4149	molybdate abc transporter
F0T03_15155	COG0725	ABC transporter, periplasmic molybdate-binding protein
F0T03_15165	COG2005	Transcriptional regulator
F0T03_15165	COG3585	molybdate ion transport
F0T03_15170	COG1119	ATPase activity
F0T03_15180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F0T03_15185	COG1085	galactose-1-phosphate uridylyltransferase
F0T03_15190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
F0T03_15195	COG2017	converts alpha-aldose to the beta-anomer
F0T03_15220	COG0588	phosphoglycerate mutase activity
F0T03_15225	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F0T03_15230	COG1230	cation diffusion facilitator family transporter
F0T03_15240	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F0T03_15265	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
F0T03_15270	COG2885	chlorophyll binding
F0T03_15275	COG0823	Involved in the tonB-independent uptake of proteins
F0T03_15280	COG3064	Membrane
F0T03_15280	COG3064	Membrane
F0T03_15285	COG0848	biopolymer transport protein
F0T03_15290	COG0811	peptide transport
F0T03_15295	COG0824	Thioesterase
F0T03_15300	COG3790	cyd operon protein YbgE
F0T03_15305	COG4890	Cyd operon protein YbgT
F0T03_15310	COG1294	oxidase, subunit
F0T03_15315	COG1271	oxidase subunit
F0T03_15320	COG0737	Belongs to the 5'-nucleotidase family
F0T03_15330	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
F0T03_15340	COG0508	dehydrogenase complex catalyzes the overall conversion of
F0T03_15345	COG0567	Dehydrogenase, E1 component
F0T03_15355	COG1053	succinate dehydrogenase
F0T03_15360	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F0T03_15365	COG2009	succinate dehydrogenase
F0T03_15375	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
F0T03_15390	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
F0T03_15395	COG1984	allophanate hydrolase subunit 2
F0T03_15400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
F0T03_15405	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F0T03_15410	COG5212	phosphodiesterase
F0T03_15420	COG3272	Protein of unknown function (DUF1722)
F0T03_15435	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F0T03_15440	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F0T03_15445	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
F0T03_15450	COG2205	protein histidine kinase activity
F0T03_15455	COG0745	RESPONSE REGULATOR receiver
F0T03_15470	COG0033	Phosphoglucomutase
F0T03_15475	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
F0T03_15480	COG0596	Alpha beta hydrolase
F0T03_15490	COG0840	transmembrane signaling receptor activity
F0T03_15500	COG0735	belongs to the Fur family
F0T03_15520	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F0T03_15525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0T03_15525	COG1263	PTS System
F0T03_15525	COG2190	(PTS) system
F0T03_15530	COG0363	glucosamine-6-phosphate deaminase activity
F0T03_15535	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
F0T03_15540	COG1940	carbohydrate kinase activity
F0T03_15540	COG1846	Transcriptional regulator
F0T03_15545	COG0647	UMP catabolic process
F0T03_15550	COG0367	asparagine synthase
F0T03_15585	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0T03_15590	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
F0T03_15595	COG1702	phosphate starvation-inducible protein PhoH
F0T03_15600	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
F0T03_15605	COG4535	Mg2 and Co2 transporter CorC
F0T03_15610	COG0815	Transfers the fatty acyl group on membrane lipoproteins
F0T03_15625	COG0765	amino acid transport
F0T03_15630	COG0765	amino acid transport
F0T03_15635	COG1126	abc transporter atp-binding protein
F0T03_15645	COG2888	peptidyl-tyrosine sulfation
F0T03_15650	COG0495	leucyl-tRNA aminoacylation
F0T03_15655	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
F0T03_15660	COG1466	dna polymerase III delta subunit
F0T03_15665	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F0T03_15670	COG0799	negative regulation of ribosome biogenesis
F0T03_15680	COG0768	penicillin binding
F0T03_15685	COG0772	Belongs to the SEDS family
F0T03_15690	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F0T03_15695	COG1686	Belongs to the peptidase S11 family
F0T03_15700	COG2921	Belongs to the UPF0250 family
F0T03_15705	COG0321	lipoyl(octanoyl) transferase activity
F0T03_15710	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F0T03_15715	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
F0T03_15720	COG3706	GGDEF domain
F0T03_15725	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
F0T03_15730	COG1278	Cold shock
F0T03_15735	COG1278	Cold shock
F0T03_15740	COG2197	response regulator
F0T03_15750	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F0T03_15765	COG5265	(ABC) transporter
F0T03_15770	COG2850	peptidyl-arginine hydroxylation
F0T03_15790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0T03_15830	COG1943	Transposase
F0T03_15850	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
F0T03_15855	COG2501	S4 domain
F0T03_15860	COG0215	cysteine-tRNA ligase activity
F0T03_15865	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F0T03_15870	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0T03_15875	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F0T03_15880	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F0T03_15885	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F0T03_15890	COG4181	ATPase activity
F0T03_15895	COG2755	lipolytic protein G-D-S-L family
F0T03_15900	COG0300	oxidoreductase activity
F0T03_15905	COG3118	belongs to the thioredoxin family
F0T03_15910	COG0330	HflC and HflK could
F0T03_15915	COG1585	Membrane protein implicated in regulation of membrane protease activity
F0T03_15920	COG0789	Transcriptional regulator
F0T03_15925	COG2217	Heavy metal translocating P-type atpase
F0T03_15930	COG3735	TraB family
F0T03_15935	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F0T03_15985	COG0582	viral genome integration into host DNA
F0T03_15990	COG0737	Belongs to the 5'-nucleotidase family
F0T03_15995	COG2223	nitrite transmembrane transporter activity
F0T03_16005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F0T03_16005	COG4651	solute:proton antiporter activity
F0T03_16010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0T03_16040	COG0438	transferase activity, transferring glycosyl groups
F0T03_16045	COG1215	transferase activity, transferring glycosyl groups
F0T03_16050	COG1442	glycosyl transferase family 8
F0T03_16050	COG1216	Glycosyl transferase, family 2
F0T03_16055	COG2244	polysaccharide biosynthetic process
F0T03_16060	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
F0T03_16065	COG0563	adenylate kinase activity
F0T03_16070	COG0326	Molecular chaperone. Has ATPase activity
F0T03_16075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F0T03_16080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
F0T03_16090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
F0T03_16095	COG2832	Protein of unknown function (DUF454)
F0T03_16110	COG3264	Mechanosensitive ion channel
F0T03_16110	COG1196	nuclear chromosome segregation
F0T03_16115	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F0T03_16120	COG1309	transcriptional regulator
F0T03_16125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_16130	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0T03_16140	COG3457	Alanine racemase
F0T03_16145	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
F0T03_16150	COG0254	rRNA binding
F0T03_16155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0T03_16160	COG0803	Belongs to the bacterial solute-binding protein 9 family
F0T03_16165	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F0T03_16170	COG1121	(ABC) transporter
F0T03_16195	COG3695	enzyme binding
F0T03_16200	COG3126	Type III secretion system lipoprotein chaperone (YscW)
F0T03_16205	COG1946	Acyl-CoA thioesterase
F0T03_16210	COG0004	ammonium transporteR
F0T03_16215	COG0347	Belongs to the P(II) protein family
F0T03_16220	COG1132	(ABC) transporter
F0T03_16225	COG1132	(ABC) transporter
F0T03_16230	COG1522	sequence-specific DNA binding
F0T03_16235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F0T03_16240	COG0561	phosphatase activity
F0T03_16245	COG4533	DNA binding
F0T03_16250	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F0T03_16255	COG0824	Thioesterase
F0T03_16260	COG1555	photosystem II stabilization
F0T03_16265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F0T03_16270	COG0776	regulation of translation
F0T03_16275	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
F0T03_16280	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
F0T03_16290	COG0544	peptidyl-prolyl cis-trans isomerase activity
F0T03_16300	COG0271	Belongs to the BolA IbaG family
F0T03_16305	COG3056	Lipoprotein
F0T03_16310	COG2223	nitrite transmembrane transporter activity
F0T03_16320	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F0T03_16325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F0T03_16330	COG1845	cytochrome c oxidase, subunit III
F0T03_16335	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F0T03_16340	COG0109	protoheme IX farnesyltransferase activity
F0T03_16345	COG2814	Major facilitator Superfamily
F0T03_16350	COG1666	GTP binding
F0T03_16355	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
F0T03_16360	COG0693	protein deglycase activity
F0T03_16365	COG0301	tRNA thio-modification
F0T03_16365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
F0T03_16370	COG1722	exodeoxyribonuclease VII activity
F0T03_16375	COG0142	geranyltranstransferase activity
F0T03_16380	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F0T03_16385	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F0T03_16390	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F0T03_16395	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0T03_16400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
F0T03_16405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0T03_16405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F0T03_16410	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F0T03_16420	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0T03_16425	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F0T03_16430	COG1862	Preprotein translocase
F0T03_16435	COG0343	queuine tRNA-ribosyltransferase activity
F0T03_16445	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
F0T03_16450	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
F0T03_16455	COG0450	alkyl hydroperoxide reductase
F0T03_16470	COG0366	Alpha amylase catalytic
F0T03_16480	COG1114	Component of the transport system for branched-chain amino acids
F0T03_16490	COG5002	protein histidine kinase activity
F0T03_16495	COG0745	RESPONSE REGULATOR receiver
F0T03_16500	COG0420	3'-5' exonuclease activity
F0T03_16505	COG0419	ATPase involved in DNA repair
F0T03_16510	COG1940	carbohydrate kinase activity
F0T03_16515	COG2974	May be involved in recombination
F0T03_16520	COG3123	guanosine phosphorylase activity
F0T03_16525	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F0T03_16535	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
F0T03_16550	COG2226	methyltransferase
F0T03_16565	COG3459	Glycosyltransferase 36 associated
F0T03_16585	COG2188	Transcriptional regulator
F0T03_16590	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
F0T03_16595	COG2313	pseudouridylate synthase activity
F0T03_16600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0T03_16605	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
F0T03_16610	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
F0T03_16625	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
F0T03_16630	COG2195	Cleaves the N-terminal amino acid of tripeptides
F0T03_16635	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F0T03_16650	COG2964	Protein conserved in bacteria
F0T03_16655	COG1181	Belongs to the D-alanine--D-alanine ligase family
F0T03_16660	COG0584	glycerophosphoryl diester phosphodiesterase
F0T03_16665	COG2991	Protein conserved in bacteria
F0T03_16670	COG1477	protein flavinylation
F0T03_16675	COG2871	sodium ion transport
F0T03_16680	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F0T03_16685	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F0T03_16690	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F0T03_16695	COG1805	sodium ion transport
F0T03_16700	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
F0T03_16705	COG3034	peptidoglycan biosynthetic process
F0T03_16710	COG0121	glutamine amidotransferase
F0T03_16715	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
F0T03_16720	COG1960	acyl-CoA dehydrogenase activity
F0T03_16725	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
F0T03_16740	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
F0T03_16745	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
F0T03_16750	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
F0T03_16755	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
F0T03_16760	COG0235	Class ii aldolase
F0T03_16765	COG0436	Aminotransferase
F0T03_16775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F0T03_16780	COG0583	DNA-binding transcription factor activity
F0T03_16785	COG2814	Major facilitator Superfamily
F0T03_16790	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F0T03_16800	COG1846	Transcriptional regulator
F0T03_16805	COG1538	Outer membrane efflux protein
F0T03_16810	COG1566	PFAM secretion protein HlyD family protein
F0T03_16815	COG2814	Major facilitator Superfamily
F0T03_16820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F0T03_16825	COG3118	belongs to the thioredoxin family
F0T03_16835	COG0045	succinate-CoA ligase (ADP-forming) activity
F0T03_16835	COG1042	CoA-binding domain protein
F0T03_16835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F0T03_16840	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F0T03_16845	COG5544	Lipoprotein
F0T03_16880	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
F0T03_16890	COG2011	ABC-type metal ion transport system permease component
F0T03_16895	COG1464	Belongs to the NlpA lipoprotein family
F0T03_16905	COG1720	tRNA m6t6A37 methyltransferase activity
F0T03_16910	COG0442	prolyl-tRNA aminoacylation
F0T03_16915	COG3015	lipoprotein NlpE involved in copper resistance
F0T03_16925	COG4681	YaeQ
F0T03_16935	COG4568	rho-dependent transcription termination
F0T03_16945	COG0037	tRNA processing
F0T03_16950	COG0346	lactoylglutathione lyase activity
F0T03_16960	COG0825	malonyl-CoA metabolic process
F0T03_16965	COG0587	DNA-directed DNA polymerase activity
F0T03_16970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F0T03_16975	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0T03_16980	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0T03_16985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
F0T03_16990	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F0T03_16995	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
F0T03_17005	COG0750	zinc metalloprotease
F0T03_17010	COG0575	Belongs to the CDS family
F0T03_17015	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F0T03_17020	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
F0T03_17030	COG0528	UMP kinase activity
F0T03_17035	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
F0T03_17040	COG0052	Belongs to the universal ribosomal protein uS2 family
F0T03_17050	COG0024	Methionine aminopeptidase
F0T03_17055	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F0T03_17060	COG2171	N-acyltransferase activity
F0T03_17075	COG0564	pseudouridine synthase activity
F0T03_17080	COG3098	single-species biofilm formation
F0T03_17090	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F0T03_17090	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
F0T03_17095	COG1611	Belongs to the LOG family
F0T03_17100	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
F0T03_17105	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
F0T03_17110	COG2363	Small membrane protein
F0T03_17115	COG0583	DNA-binding transcription factor activity
F0T03_17125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F0T03_17130	COG2166	iron-sulfur cluster assembly
F0T03_17135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F0T03_17140	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
F0T03_17160	COG0860	N-Acetylmuramoyl-L-alanine amidase
F0T03_17165	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
F0T03_17165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
F0T03_17170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F0T03_17175	COG1074	ATP-dependent DNA helicase activity
F0T03_17180	COG1025	Belongs to the peptidase M16 family
F0T03_17185	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F0T03_17210	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
F0T03_17215	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
F0T03_17225	COG1051	belongs to the nudix hydrolase family
F0T03_17235	COG3066	DNA modification
F0T03_17240	COG0861	Integral membrane protein TerC family
F0T03_17245	COG0667	Aldo Keto reductase
F0T03_17250	COG0477	Major facilitator Superfamily
F0T03_17255	COG0204	Acyl-transferase
F0T03_17255	COG0318	PFAM AMP-dependent synthetase and ligase
F0T03_17265	COG1609	Transcriptional regulator
F0T03_17270	COG0019	diaminopimelate decarboxylase activity
F0T03_17275	COG0583	DNA-binding transcription factor activity
F0T03_17280	COG2814	Major facilitator Superfamily
F0T03_17285	COG0583	DNA-binding transcription factor activity
F0T03_17345	COG2165	general secretion pathway protein
F0T03_17375	COG0288	reversible hydration of carbon dioxide
F0T03_17380	COG1733	regulation of RNA biosynthetic process
F0T03_17385	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_17400	COG0484	heat shock protein binding
F0T03_17405	COG1609	Transcriptional regulator
F0T03_17410	COG2271	Major facilitator Superfamily
F0T03_17425	COG1522	sequence-specific DNA binding
F0T03_17430	COG3706	GGDEF domain
F0T03_17470	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F0T03_17480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F0T03_17485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F0T03_17490	COG4974	Belongs to the 'phage' integrase family
F0T03_17495	COG0716	FMN binding
F0T03_17500	COG4452	Inner membrane protein CreD
F0T03_17505	COG2205	protein histidine kinase activity
F0T03_17510	COG0745	RESPONSE REGULATOR receiver
F0T03_17520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F0T03_17525	COG0354	folic acid binding
F0T03_17530	COG1272	protein, Hemolysin III
F0T03_17540	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_17550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0T03_17550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
F0T03_17555	COG0509	glycine decarboxylation via glycine cleavage system
F0T03_17560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
F0T03_17570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0T03_17575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F0T03_17580	COG0006	proline dipeptidase activity
F0T03_17585	COG3079	Belongs to the UPF0149 family
F0T03_17590	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
F0T03_17600	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F0T03_17605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F0T03_17610	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
F0T03_17615	COG0583	DNA-binding transcription factor activity
F0T03_17625	COG1279	arginine transmembrane transporter activity
F0T03_17640	COG0191	fructose-bisphosphate aldolase activity
F0T03_17645	COG0126	phosphoglycerate kinase activity
F0T03_17650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F0T03_17660	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F0T03_17665	COG0501	Belongs to the peptidase M48B family
F0T03_17675	COG1166	arginine decarboxylase activity
F0T03_17695	COG0640	Transcriptional regulator
F0T03_17700	COG3091	SprT-like family
F0T03_17705	COG2356	endonuclease I
F0T03_17710	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F0T03_17715	COG0189	ligase activity
F0T03_17720	COG1678	Uncharacterized ACR, COG1678
F0T03_17725	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F0T03_17730	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0T03_17740	COG2805	Type II/IV secretion system protein
F0T03_17745	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F0T03_17750	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F0T03_17755	COG0762	integral membrane protein
F0T03_17760	COG1872	DUF167
F0T03_17765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
F0T03_17770	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F0T03_17780	COG2066	Belongs to the glutaminase family
F0T03_17785	COG3171	Protein conserved in bacteria
F0T03_17790	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F0T03_17795	COG1194	a g-specific adenine glycosylase
F0T03_17805	COG0741	lytic transglycosylase activity
F0T03_17815	COG1982	Orn Lys Arg decarboxylase major
F0T03_17980	COG2885	chlorophyll binding
F0T03_18010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F0T03_18075	COG1157	protein secretion by the type III secretion system
F0T03_18085	COG4789	Type iii secretion
F0T03_18160	COG5002	protein histidine kinase activity
F0T03_18175	COG1289	transmembrane transporter activity
F0T03_18200	COG0024	Methionine aminopeptidase
F0T03_18205	COG4604	ABC transporter, ATP-binding protein
F0T03_18210	COG4605	iron ion homeostasis
F0T03_18220	COG4607	ABC-type enterochelin transport system periplasmic component
F0T03_18225	COG1017	nitric oxide dioxygenase activity
F0T03_18225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F0T03_18235	COG0477	Major facilitator Superfamily
F0T03_18240	COG1609	Transcriptional regulator
F0T03_18250	COG1283	sodium-dependent phosphate transmembrane transporter activity
F0T03_18255	COG2195	Cleaves the N-terminal amino acid of tripeptides
F0T03_18260	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
F0T03_18275	COG0477	Major facilitator Superfamily
F0T03_18290	COG0583	DNA-binding transcription factor activity
F0T03_18305	COG0471	metal ion transport
F0T03_18315	COG5001	Diguanylate cyclase
F0T03_18325	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
F0T03_18335	COG0477	Major facilitator Superfamily
F0T03_18340	COG1566	PFAM secretion protein HlyD family protein
F0T03_18345	COG2197	response regulator
F0T03_18350	COG0784	Response regulator, receiver
F0T03_18350	COG2205	protein histidine kinase activity
F0T03_18350	COG2198	Histidine kinase
F0T03_18350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0T03_18355	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F0T03_18360	COG0679	Auxin Efflux Carrier
F0T03_18365	COG0028	Belongs to the TPP enzyme family
F0T03_18390	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
F0T03_18395	COG0309	Hydrogenase expression formation protein (HypE)
F0T03_18400	COG0409	Hydrogenase expression formation protein
F0T03_18405	COG0298	carbon dioxide binding
F0T03_18410	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
F0T03_18415	COG0375	protein maturation
F0T03_18420	COG1773	rubredoxin
F0T03_18425	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
F0T03_18430	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
F0T03_18435	COG5557	Pfam Polysulphide reductase, NrfD
F0T03_18440	COG0437	4 iron, 4 sulfur cluster binding
F0T03_18445	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
F0T03_18450	COG3133	Outer membrane lipoprotein
F0T03_18460	COG3710	Transcriptional regulator
F0T03_18460	COG0457	Tetratricopeptide repeat
F0T03_18465	COG3829	transcription factor binding
F0T03_18470	COG0840	transmembrane signaling receptor activity
F0T03_18475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F0T03_18480	COG2271	Major facilitator Superfamily
F0T03_18485	COG1028	Short-chain dehydrogenase reductase Sdr
F0T03_18490	COG3433	isochorismatase activity
F0T03_18490	COG1535	isochorismatase
F0T03_18495	COG1021	2,3-dihydroxybenzoate-AMP ligase
F0T03_18500	COG1169	isochorismate synthase
F0T03_18505	COG4592	Periplasmic binding protein
F0T03_18515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0T03_18520	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F0T03_18525	COG1120	ATPase activity
F0T03_18530	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F0T03_18545	COG4774	siderophore transport
F0T03_18555	COG5569	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_18565	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F0T03_18570	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F0T03_18645	COG0848	biopolymer transport protein
F0T03_18650	COG0811	peptide transport
F0T03_18660	COG0586	Pfam SNARE associated Golgi protein
F0T03_18665	COG2207	Transcriptional regulator
F0T03_18675	COG1979	alcohol dehydrogenase
F0T03_18680	COG0656	L-ascorbic acid biosynthetic process
F0T03_18690	COG2132	Multicopper oxidase
F0T03_18695	COG0204	Acyl-transferase
F0T03_18700	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F0T03_18710	COG2249	NAD(P)H dehydrogenase (quinone) activity
F0T03_18725	COG0187	DNA topoisomerase II activity
F0T03_18730	COG3150	esterase
F0T03_18735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F0T03_18740	COG3151	Protein conserved in bacteria
F0T03_18745	COG0494	nUDIX hydrolase
F0T03_18750	COG1538	Outer membrane efflux protein
F0T03_18760	COG0754	glutathionylspermidine amidase activity
F0T03_18765	COG3384	dioxygenase
F0T03_18770	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F0T03_18780	COG0531	amino acid
F0T03_18785	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
F0T03_18785	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F0T03_18790	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F0T03_18795	COG3025	triphosphatase activity
F0T03_18800	COG4991	sh3 domain protein
F0T03_18805	COG0617	tRNA 3'-terminal CCA addition
F0T03_18810	COG1968	undecaprenyl-diphosphatase activity
F0T03_18815	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F0T03_18820	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
F0T03_18825	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
F0T03_18835	COG0358	DNA primase activity
F0T03_18840	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F0T03_18865	COG2003	Belongs to the UPF0758 family
F0T03_18870	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
F0T03_18900	COG2378	regulation of single-species biofilm formation
F0T03_18910	COG3596	GTP binding
F0T03_18940	COG1479	Protein of unknown function DUF262
F0T03_18950	COG1204	response to ionizing radiation
F0T03_18995	COG0542	response to heat
F0T03_19010	COG4983	Phage plasmid primase, P4 family domain protein
F0T03_19050	COG2066	Belongs to the glutaminase family
F0T03_19055	COG0531	amino acid
F0T03_19060	COG0076	glutamate decarboxylase activity
F0T03_19070	COG2814	Major facilitator Superfamily
F0T03_19075	COG3247	response to pH
F0T03_19085	COG2378	regulation of single-species biofilm formation
F0T03_19095	COG1902	pentaerythritol trinitrate reductase activity
F0T03_19095	COG0446	pyridine nucleotide-disulphide oxidoreductase
F0T03_19100	COG2813	Specifically methylates the guanine in position
F0T03_19110	COG1451	nucleotide metabolic process
F0T03_19115	COG0673	inositol 2-dehydrogenase activity
F0T03_19120	COG0861	Integral membrane protein TerC family
F0T03_19125	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
F0T03_19135	COG2721	sulfolactate sulfo-lyase activity
F0T03_19140	COG0246	Mannitol dehydrogenase
F0T03_19145	COG1904	glucuronate isomerase
F0T03_19150	COG2271	Major facilitator Superfamily
F0T03_19165	COG0586	Pfam SNARE associated Golgi protein
F0T03_19180	COG4575	ribosome binding
F0T03_19185	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
F0T03_19195	COG2259	Doxx family
F0T03_19200	COG0435	Glutathione S-transferase
F0T03_19205	COG0583	DNA-binding transcription factor activity
F0T03_19210	COG1741	Belongs to the pirin family
F0T03_19215	COG1064	alcohol dehydrogenase
F0T03_19220	COG0667	Aldo Keto reductase
F0T03_19250	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
F0T03_19260	COG0792	nuclease activity
F0T03_19265	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
F0T03_19270	COG2823	Periplasmic or secreted lipoprotein
F0T03_19275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F0T03_19280	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
F0T03_19285	COG5002	protein histidine kinase activity
F0T03_19285	COG2198	Histidine kinase
F0T03_19285	COG0784	Response regulator, receiver
F0T03_19290	COG1242	4 iron, 4 sulfur cluster binding
F0T03_19295	COG0070	glutamate synthase
F0T03_19295	COG0069	glutamate synthase activity
F0T03_19295	COG0067	glutamate synthase
F0T03_19300	COG0493	'glutamate synthase
F0T03_19310	COG2969	positive regulation of protein catabolic process
F0T03_19315	COG0625	glutathione transferase activity
F0T03_19320	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F0T03_19325	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
F0T03_19330	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F0T03_19335	COG3105	Protein conserved in bacteria
F0T03_19340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0T03_19345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F0T03_19350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F0T03_19355	COG5007	Belongs to the BolA IbaG family
F0T03_19360	COG3113	response to antibiotic
F0T03_19365	COG2854	intermembrane phospholipid transfer
F0T03_19370	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F0T03_19375	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F0T03_19380	COG1127	ABC transporter
F0T03_19385	COG0530	calcium, potassium:sodium antiporter activity
F0T03_19390	COG0517	IMP dehydrogenase activity
F0T03_19390	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F0T03_19395	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F0T03_19400	COG3117	lipopolysaccharide transmembrane transporter activity
F0T03_19405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F0T03_19410	COG1137	ATPase activity
F0T03_19415	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
F0T03_19425	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0T03_19430	COG1660	Displays ATPase and GTPase activities
F0T03_19435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0T03_19445	COG0540	Belongs to the ATCase OTCase family
F0T03_19450	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
F0T03_19460	COG2308	Evidence 4 Homologs of previously reported genes of
F0T03_19480	COG0366	Alpha amylase catalytic
F0T03_19485	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
F0T03_19485	COG1263	PTS System
F0T03_19490	COG1609	Transcriptional regulator
F0T03_19495	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F0T03_19500	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0T03_19500	COG3711	transcriptional antiterminator
F0T03_19505	COG2706	6-phosphogluconolactonase activity
F0T03_19520	COG3964	amidohydrolase
F0T03_19550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0T03_19555	COG3783	Cytochrome b(562)
F0T03_19560	COG0312	modulator of DNA gyrase
F0T03_19565	COG3028	Belongs to the UPF0307 family
F0T03_19570	COG2732	(Barnase) inhibitor
F0T03_19585	COG1289	transmembrane transporter activity
F0T03_19590	COG1566	PFAM secretion protein HlyD family protein
F0T03_19600	COG0583	DNA-binding transcription factor activity
F0T03_19605	COG0312	modulator of DNA gyrase
F0T03_19610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F0T03_19615	COG3164	Protein of unknown function
F0T03_19620	COG1530	ribonuclease E activity
F0T03_19630	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F0T03_19635	COG1792	Involved in formation and maintenance of cell shape
F0T03_19640	COG1077	Cell shape determining protein MreB Mrl
F0T03_19645	COG2200	EAL domain
F0T03_19645	COG2199	diguanylate cyclase activity
F0T03_19650	COG0604	alcohol dehydrogenase
F0T03_19660	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
F0T03_19665	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F0T03_19670	COG0511	ligase activity, forming carbon-carbon bonds
F0T03_19675	COG0439	Biotin carboxylase
F0T03_19680	COG3924	membrane
F0T03_19685	COG4145	pantothenate transmembrane transporter activity
F0T03_19690	COG2264	protein methyltransferase activity
F0T03_19695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F0T03_19700	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F0T03_19705	COG0745	RESPONSE REGULATOR receiver
F0T03_19705	COG3706	GGDEF domain
F0T03_19710	COG3133	Outer membrane lipoprotein
F0T03_19715	COG1278	Cold shock
F0T03_19720	COG1278	Cold shock
F0T03_19725	COG0471	metal ion transport
F0T03_19730	COG1560	Kdo2-lipid A biosynthetic process
F0T03_19740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0T03_19745	COG4597	amino acid ABC transporter
F0T03_19750	COG0765	amino acid transport
F0T03_19755	COG1126	abc transporter atp-binding protein
F0T03_19765	COG1380	Effector of murein hydrolase LrgA
F0T03_19770	COG0583	DNA-binding transcription factor activity
F0T03_19775	COG0025	NhaP-type Na H and K H
F0T03_19780	COG2252	PERMEase
F0T03_19790	COG0629	single-stranded DNA binding
F0T03_19795	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F0T03_19800	COG2315	Protein conserved in bacteria
F0T03_19805	COG1448	Aminotransferase
F0T03_19810	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F0T03_19815	COG0305	Participates in initiation and elongation during chromosome replication
F0T03_19835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F0T03_19845	COG0735	belongs to the Fur family
F0T03_19850	COG3237	CsbD-like
F0T03_19855	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F0T03_19860	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
F0T03_19865	COG2937	Belongs to the GPAT DAPAT family
F0T03_19870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F0T03_19875	COG3161	chorismate lyase activity
F0T03_19890	COG4580	involved in the transport of maltose and maltodextrins
F0T03_19905	COG2182	Extracellular solute-binding protein
F0T03_19910	COG1175	transmembrane transport
F0T03_19915	COG3833	ABC-type maltose transport systems, permease component
F0T03_19920	COG3223	Belongs to the PsiE family
F0T03_19930	COG0527	aspartate kinase activity
F0T03_19950	COG3852	Histidine kinase
F0T03_19955	COG2204	response regulator
F0T03_19960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F0T03_19965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F0T03_19970	COG2031	fatty acid transporter
F0T03_19975	COG0183	Belongs to the thiolase family
F0T03_19980	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
F0T03_19985	COG2224	Isocitrate lyase
F0T03_19990	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F0T03_19995	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
F0T03_20045	COG0138	bifunctional purine biosynthesis protein purh
F0T03_20050	COG0151	Belongs to the GarS family
F0T03_20065	COG3068	Protein conserved in bacteria
F0T03_20070	COG1515	deoxyribonuclease V activity
F0T03_20075	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
F0T03_20080	COG2816	NAD+ diphosphatase activity
F0T03_20085	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
F0T03_20090	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
F0T03_20100	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
F0T03_20105	COG2104	thiamine diphosphate biosynthetic process
F0T03_20110	COG2022	thiamine diphosphate biosynthetic process
F0T03_20115	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
F0T03_20120	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
F0T03_20125	COG0085	RNA polymerase activity
F0T03_20130	COG0222	ribosome binding
F0T03_20135	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
F0T03_20140	COG0081	regulation of translation
F0T03_20145	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
F0T03_20150	COG0250	Participates in transcription elongation, termination and antitermination
F0T03_20155	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F0T03_20165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F0T03_20195	COG1072	(Pantothenic acid kinase))
F0T03_20200	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
F0T03_20200	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
F0T03_20235	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F0T03_20240	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
F0T03_20245	COG0009	L-threonylcarbamoyladenylate synthase
F0T03_20250	COG0551	DNA topoisomerase type I activity
F0T03_20260	COG0758	DNA mediated transformation
F0T03_20265	COG0242	peptide deformylase activity
F0T03_20270	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
F0T03_20275	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
F0T03_20275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
F0T03_20280	COG0569	domain protein
F0T03_20285	COG1970	mechanosensitive ion channel activity
F0T03_20290	COG3036	rescue of stalled ribosome
F0T03_20295	COG0789	Transcriptional regulator
F0T03_20305	COG0203	ribosomal protein L17
F0T03_20310	COG0202	RNA polymerase activity
F0T03_20315	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
F0T03_20320	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
F0T03_20325	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
F0T03_20330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
F0T03_20335	COG0201	protein transport
F0T03_20340	COG0200	Binds to the 23S rRNA
F0T03_20345	COG1841	ribosomal large subunit assembly
F0T03_20350	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
F0T03_20355	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
F0T03_20360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
F0T03_20370	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
F0T03_20380	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
F0T03_20385	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
F0T03_20390	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
F0T03_20395	COG0255	Belongs to the universal ribosomal protein uL29 family
F0T03_20400	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
F0T03_20405	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
F0T03_20415	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
F0T03_20425	COG0089	rRNA binding
F0T03_20435	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
F0T03_20440	COG0051	transcription antitermination factor activity, RNA binding
F0T03_20455	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
F0T03_20465	COG0049	tRNA binding
F0T03_20470	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
F0T03_20475	COG2168	tRNA wobble position uridine thiolation
F0T03_20480	COG2923	Belongs to the DsrF TusC family
F0T03_20485	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F0T03_20490	COG2964	Protein conserved in bacteria
F0T03_20495	COG0545	Peptidyl-prolyl cis-trans isomerase
F0T03_20505	COG1047	Peptidyl-prolyl cis-trans
F0T03_20510	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F0T03_20520	COG2249	NAD(P)H dehydrogenase (quinone) activity
F0T03_20525	COG0488	(ABC) transporter
F0T03_20535	COG2175	clavaminate synthase activity
F0T03_20540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F0T03_20550	COG4521	taurine ABC transporter
F0T03_20565	COG0429	hydrolase of the alpha beta-hydrolase fold
F0T03_20570	COG3089	Belongs to the UPF0270 family
F0T03_20575	COG3954	Phosphoribulokinase
F0T03_20580	COG1765	OsmC-like protein
F0T03_20590	COG1289	transmembrane transporter activity
F0T03_20605	COG0433	COG0433 Predicted ATPase
F0T03_20610	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F0T03_20615	COG1486	melibiose metabolic process
F0T03_20620	COG1609	Transcriptional regulator
F0T03_20635	COG0738	Major facilitator superfamily
F0T03_20640	COG0402	S-adenosylhomocysteine deaminase activity
F0T03_20645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F0T03_20650	COG2146	nitrite reductase [NAD(P)H] activity
F0T03_20660	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F0T03_20660	COG1648	precorrin-2 dehydrogenase activity
F0T03_20665	COG0180	Tryptophanyl-tRNA synthetase
F0T03_20675	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F0T03_20695	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
F0T03_20700	COG4796	Type ii and iii secretion system protein
F0T03_20725	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
F0T03_20730	COG0494	nUDIX hydrolase
F0T03_20740	COG1011	Hydrolase
F0T03_20745	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F0T03_20755	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
F0T03_20765	COG0745	RESPONSE REGULATOR receiver
F0T03_20770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F0T03_20775	COG2183	response to ionizing radiation
F0T03_20785	COG1918	ferrous iron import across plasma membrane
F0T03_20790	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
F0T03_20805	COG0596	Alpha beta hydrolase
F0T03_20810	COG1040	competence protein
F0T03_20815	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
F0T03_20815	COG0316	Belongs to the HesB IscA family
F0T03_20820	COG1640	4-alpha-glucanotransferase
F0T03_20825	COG0058	SHG alpha-glucan phosphorylase activity
F0T03_20830	COG2909	trisaccharide binding
F0T03_20840	COG0705	Rhomboid family
F0T03_20845	COG1349	DNA-binding transcription factor activity
F0T03_20850	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
F0T03_20855	COG0058	SHG alpha-glucan phosphorylase activity
F0T03_20860	COG0297	glycogen (starch) synthase activity
F0T03_20870	COG1523	belongs to the glycosyl hydrolase 13 family
F0T03_20875	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
F0T03_20880	COG3275	phosphorelay sensor kinase activity
F0T03_20900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
F0T03_20905	COG2095	MarC family integral membrane protein
F0T03_20910	COG3265	gluconokinase activity
F0T03_20915	COG2610	gluconate transmembrane transporter activity
F0T03_20920	COG1609	Transcriptional regulator
F0T03_20925	COG1741	Belongs to the pirin family
F0T03_20935	COG1247	-acetyltransferase
F0T03_20940	COG1082	Xylose isomerase domain protein TIM barrel
F0T03_20950	COG0673	inositol 2-dehydrogenase activity
F0T03_20955	COG3962	Belongs to the TPP enzyme family
F0T03_20960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0T03_20970	COG3718	enzyme involved in inositol metabolism
F0T03_20980	COG0477	Major facilitator Superfamily
F0T03_20980	COG2814	Major facilitator Superfamily
F0T03_20990	COG2814	Major facilitator Superfamily
F0T03_20995	COG0583	DNA-binding transcription factor activity
F0T03_21000	COG0561	phosphatase activity
F0T03_21005	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
F0T03_21010	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F0T03_21010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F0T03_21015	COG0583	DNA-binding transcription factor activity
F0T03_21020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F0T03_21020	COG1648	precorrin-2 dehydrogenase activity
F0T03_21030	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
F0T03_21040	COG4865	methylaspartate mutase activity
F0T03_21045	COG3799	methylaspartate ammonia-lyase activity
F0T03_21060	COG1301	dicarboxylic acid transport
F0T03_21065	COG2081	HI0933 family
F0T03_21070	COG0306	phosphate transporter
F0T03_21080	COG0589	response to stress
F0T03_21095	COG0742	ribosomal rna small subunit methyltransferase
F0T03_21105	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F0T03_21110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F0T03_21135	COG1295	ribonuclease BN
F0T03_21140	COG2134	cdp-diacylglycerol pyrophosphatase
F0T03_21145	COG2982	Protein involved in outer membrane biogenesis
F0T03_21150	COG2200	EAL domain
F0T03_21155	COG1942	4-Oxalocrotonate Tautomerase
F0T03_21160	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F0T03_21165	COG0612	Peptidase, M16
F0T03_21170	COG1301	dicarboxylic acid transport
F0T03_21180	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
F0T03_21185	COG2200	EAL domain
F0T03_21185	COG2199	diguanylate cyclase activity
F0T03_21195	COG3118	belongs to the thioredoxin family
F0T03_21195	COG0457	Tetratricopeptide repeat
F0T03_21200	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
F0T03_21205	COG1215	transferase activity, transferring glycosyl groups
F0T03_21210	COG1215	transferase activity, transferring glycosyl groups
F0T03_21235	COG2194	sulfuric ester hydrolase activity
F0T03_21240	COG4608	Belongs to the ABC transporter superfamily
F0T03_21245	COG0444	Belongs to the ABC transporter superfamily
F0T03_21250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F0T03_21255	COG0601	transmembrane transport
F0T03_21260	COG0747	negative chemotaxis
F0T03_21265	COG3210	domain, Protein
F0T03_21270	COG2831	hemolysin activation secretion protein
F0T03_21290	COG3851	Histidine kinase
F0T03_21295	COG2197	response regulator
F0T03_21300	COG2194	sulfuric ester hydrolase activity
F0T03_21305	COG1764	response to oxidative stress
F0T03_21325	COG0463	Glycosyl transferase, family 2
F0T03_21330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F0T03_21340	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
F0T03_21355	COG2986	histidine ammonia-lyase
F0T03_21360	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
F0T03_21385	COG0288	reversible hydration of carbon dioxide
F0T03_21390	COG0786	glutamate:sodium symporter activity
F0T03_21400	COG2207	Transcriptional regulator
F0T03_21400	COG1609	Transcriptional regulator
F0T03_21405	COG4214	carbohydrate transport
F0T03_21415	COG4213	ABC transporter substrate-binding protein
F0T03_21420	COG2115	Belongs to the xylose isomerase family
F0T03_21425	COG1070	Carbohydrate kinase
F0T03_21430	COG3121	Chaperone
F0T03_21435	COG1335	isochorismatase
F0T03_21445	COG3274	enterobacterial common antigen metabolic process
F0T03_21455	COG3276	selenocysteine insertion sequence binding
F0T03_21460	COG1921	L-seryl-tRNASec selenium transferase activity
F0T03_21465	COG3058	Necessary for formate dehydrogenase activity
F0T03_21470	COG2864	formate dehydrogenase
F0T03_21475	COG0437	4 iron, 4 sulfur cluster binding
F0T03_21485	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F0T03_21490	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F0T03_21495	COG0840	transmembrane signaling receptor activity
F0T03_21500	COG2258	MOSC domain
F0T03_21510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F0T03_21520	COG3722	fumarate hydratase activity
F0T03_21525	COG0246	Mannitol dehydrogenase
F0T03_21530	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F0T03_21530	COG2213	PTS system mannitol-specific
F0T03_21540	COG0751	glycine-tRNA ligase activity
F0T03_21545	COG0752	glycyl-tRNA synthetase alpha subunit
F0T03_21550	COG2818	Glycosylase
F0T03_21555	COG0456	acetyltransferase
F0T03_21580	COG0366	Alpha amylase catalytic
F0T03_21585	COG3977	Valine--pyruvate aminotransferase
F0T03_21590	COG2985	domain, Protein
F0T03_21590	COG0569	domain protein
F0T03_21605	COG5645	(Lipo)protein
F0T03_21610	COG0823	Involved in the tonB-independent uptake of proteins
F0T03_21620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F0T03_21625	COG2423	ornithine cyclodeaminase activity
F0T03_21630	COG0561	phosphatase activity
F0T03_21635	COG0187	DNA topoisomerase II activity
F0T03_21640	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
F0T03_21645	COG0592	DNA-directed DNA polymerase activity
F0T03_21650	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
F0T03_21665	COG0230	Belongs to the bacterial ribosomal protein bL34 family
F0T03_21670	COG0594	ribonuclease P activity
F0T03_21680	COG0706	membrane insertase activity
F0T03_21685	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
F0T03_21690	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
F0T03_21700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F0T03_21705	COG2011	ABC-type metal ion transport system permease component
F0T03_21710	COG0840	transmembrane signaling receptor activity
F0T03_21715	COG0431	NADPH-dependent FMN reductase
F0T03_21735	COG2252	PERMEase
F0T03_21740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F0T03_21745	COG0765	amino acid transport
F0T03_21750	COG0765	amino acid transport
F0T03_21755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F0T03_21765	COG0704	Plays a role in the regulation of phosphate uptake
F0T03_21775	COG0581	inorganic phosphate transmembrane transporter activity
F0T03_21780	COG0573	inorganic phosphate transmembrane transporter activity
F0T03_21785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F0T03_21790	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F0T03_21795	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
F0T03_21800	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F0T03_21805	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
F0T03_21815	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
F0T03_21820	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
F0T03_21825	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
F0T03_21835	COG0356	it plays a direct role in the translocation of protons across the membrane
F0T03_21840	COG3312	ion transport
F0T03_21845	COG0357	Ribosomal RNA small subunit methyltransferase G
F0T03_21850	COG0445	tRNA wobble uridine modification