locus-tag	class	description
OP863_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OP863_00010	COG0592	DNA-directed DNA polymerase activity
OP863_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OP863_00020	COG0187	DNA topoisomerase II activity
OP863_00025	COG0561	phosphatase activity
OP863_00030	COG2423	ornithine cyclodeaminase activity
OP863_00050	COG3727	T/G mismatch-specific endonuclease activity
OP863_00060	COG0823	Involved in the tonB-independent uptake of proteins
OP863_00065	COG5645	(Lipo)protein
OP863_00080	COG0569	domain protein
OP863_00080	COG2985	domain, Protein
OP863_00085	COG3977	Valine--pyruvate aminotransferase
OP863_00090	COG0366	Alpha amylase catalytic
OP863_00095	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OP863_00100	COG3668	Plasmid stabilization system
OP863_00105	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OP863_00135	COG0456	acetyltransferase
OP863_00140	COG2818	Glycosylase
OP863_00150	COG0752	glycyl-tRNA synthetase alpha subunit
OP863_00155	COG0751	glycine-tRNA ligase activity
OP863_00165	COG2213	PTS system mannitol-specific
OP863_00165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP863_00170	COG0246	Mannitol dehydrogenase
OP863_00175	COG3722	fumarate hydratase activity
OP863_00185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP863_00195	COG0840	transmembrane signaling receptor activity
OP863_00200	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OP863_00205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OP863_00215	COG0437	4 iron, 4 sulfur cluster binding
OP863_00220	COG2864	formate dehydrogenase
OP863_00225	COG3058	Necessary for formate dehydrogenase activity
OP863_00230	COG1921	L-seryl-tRNASec selenium transferase activity
OP863_00235	COG3276	selenocysteine insertion sequence binding
OP863_00255	COG3274	enterobacterial common antigen metabolic process
OP863_00265	COG1335	isochorismatase
OP863_00270	COG3121	Chaperone
OP863_00275	COG1070	Carbohydrate kinase
OP863_00280	COG2115	Belongs to the xylose isomerase family
OP863_00285	COG4213	ABC transporter substrate-binding protein
OP863_00295	COG4214	carbohydrate transport
OP863_00300	COG1609	Transcriptional regulator
OP863_00300	COG2207	Transcriptional regulator
OP863_00310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP863_00310	COG2205	protein histidine kinase activity
OP863_00330	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OP863_00335	COG2986	histidine ammonia-lyase
OP863_00355	COG1764	response to oxidative stress
OP863_00360	COG2194	sulfuric ester hydrolase activity
OP863_00365	COG2197	response regulator
OP863_00370	COG3851	Histidine kinase
OP863_00375	COG2271	Major facilitator Superfamily
OP863_00390	COG2831	hemolysin activation secretion protein
OP863_00395	COG3210	domain, Protein
OP863_00400	COG0747	negative chemotaxis
OP863_00405	COG0601	transmembrane transport
OP863_00410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OP863_00415	COG0444	Belongs to the ABC transporter superfamily
OP863_00420	COG4608	Belongs to the ABC transporter superfamily
OP863_00425	COG2194	sulfuric ester hydrolase activity
OP863_00445	COG1192	Involved in chromosome partitioning
OP863_00450	COG1215	transferase activity, transferring glycosyl groups
OP863_00455	COG1215	transferase activity, transferring glycosyl groups
OP863_00460	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OP863_00465	COG0457	Tetratricopeptide repeat
OP863_00465	COG3118	belongs to the thioredoxin family
OP863_00470	COG2199	diguanylate cyclase activity
OP863_00470	COG2200	EAL domain
OP863_00475	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OP863_00485	COG1301	dicarboxylic acid transport
OP863_00490	COG0612	Peptidase, M16
OP863_00495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OP863_00500	COG1942	4-Oxalocrotonate Tautomerase
OP863_00505	COG2200	EAL domain
OP863_00510	COG2982	Protein involved in outer membrane biogenesis
OP863_00515	COG2134	cdp-diacylglycerol pyrophosphatase
OP863_00525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OP863_00530	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OP863_00540	COG0742	ribosomal rna small subunit methyltransferase
OP863_00555	COG0589	response to stress
OP863_00565	COG0306	phosphate transporter
OP863_00570	COG2081	HI0933 family
OP863_00685	COG0488	(ABC) transporter
OP863_00700	COG3718	enzyme involved in inositol metabolism
OP863_00710	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OP863_00715	COG3962	Belongs to the TPP enzyme family
OP863_00720	COG0673	inositol 2-dehydrogenase activity
OP863_00725	COG1082	Xylose isomerase domain protein TIM barrel
OP863_00730	COG1082	Xylose isomerase domain protein TIM barrel
OP863_00735	COG1247	-acetyltransferase
OP863_00740	COG1741	Belongs to the pirin family
OP863_00745	COG1609	Transcriptional regulator
OP863_00750	COG2610	gluconate transmembrane transporter activity
OP863_00755	COG3265	gluconokinase activity
OP863_00760	COG2095	MarC family integral membrane protein
OP863_00765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OP863_00775	COG3275	phosphorelay sensor kinase activity
OP863_00780	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OP863_00785	COG1523	belongs to the glycosyl hydrolase 13 family
OP863_00795	COG0297	glycogen (starch) synthase activity
OP863_00800	COG0058	SHG alpha-glucan phosphorylase activity
OP863_00805	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OP863_00810	COG1349	DNA-binding transcription factor activity
OP863_00815	COG0705	Rhomboid family
OP863_00825	COG2909	trisaccharide binding
OP863_00830	COG0058	SHG alpha-glucan phosphorylase activity
OP863_00835	COG1640	4-alpha-glucanotransferase
OP863_00845	COG0316	Belongs to the HesB IscA family
OP863_00845	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OP863_00855	COG0596	Alpha beta hydrolase
OP863_00870	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OP863_00875	COG1918	ferrous iron import across plasma membrane
OP863_00880	COG2183	response to ionizing radiation
OP863_00905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OP863_00925	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OP863_00935	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
OP863_00940	COG1011	Hydrolase
OP863_00950	COG0494	nUDIX hydrolase
OP863_00955	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OP863_00980	COG4796	Type ii and iii secretion system protein
OP863_00985	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OP863_01005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OP863_01015	COG0180	Tryptophanyl-tRNA synthetase
OP863_01020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OP863_01020	COG1648	precorrin-2 dehydrogenase activity
OP863_01035	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OP863_01040	COG0402	S-adenosylhomocysteine deaminase activity
OP863_01045	COG0738	Major facilitator superfamily
OP863_01050	COG1609	Transcriptional regulator
OP863_01055	COG1486	melibiose metabolic process
OP863_01060	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OP863_01065	COG0433	COG0433 Predicted ATPase
OP863_01085	COG1289	transmembrane transporter activity
OP863_01095	COG1765	OsmC-like protein
OP863_01100	COG3954	Phosphoribulokinase
OP863_01105	COG3089	Belongs to the UPF0270 family
OP863_01110	COG0429	hydrolase of the alpha beta-hydrolase fold
OP863_01125	COG4521	taurine ABC transporter
OP863_01135	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OP863_01140	COG2175	clavaminate synthase activity
OP863_01160	COG0488	(ABC) transporter
OP863_01165	COG2249	NAD(P)H dehydrogenase (quinone) activity
OP863_01175	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OP863_01180	COG1047	Peptidyl-prolyl cis-trans
OP863_01185	COG2900	Belongs to the SlyX family
OP863_01190	COG0545	Peptidyl-prolyl cis-trans isomerase
OP863_01195	COG2964	Protein conserved in bacteria
OP863_01200	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OP863_01205	COG2923	Belongs to the DsrF TusC family
OP863_01210	COG2168	tRNA wobble position uridine thiolation
OP863_01215	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OP863_01220	COG0049	tRNA binding
OP863_01230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OP863_01245	COG0051	transcription antitermination factor activity, RNA binding
OP863_01250	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OP863_01260	COG0089	rRNA binding
OP863_01265	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OP863_01270	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OP863_01275	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OP863_01280	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OP863_01285	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OP863_01290	COG0255	Belongs to the universal ribosomal protein uL29 family
OP863_01295	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OP863_01300	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OP863_01305	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OP863_01315	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OP863_01325	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OP863_01330	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OP863_01340	COG1841	ribosomal large subunit assembly
OP863_01345	COG0200	Binds to the 23S rRNA
OP863_01350	COG0201	protein transport
OP863_01355	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OP863_01360	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OP863_01365	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OP863_01370	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OP863_01375	COG0202	RNA polymerase activity
OP863_01380	COG0203	ribosomal protein L17
OP863_01390	COG0789	Transcriptional regulator
OP863_01395	COG3036	rescue of stalled ribosome
OP863_01400	COG1970	mechanosensitive ion channel activity
OP863_01410	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OP863_01410	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OP863_01415	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OP863_01420	COG0242	peptide deformylase activity
OP863_01425	COG0758	DNA mediated transformation
OP863_01435	COG0551	DNA topoisomerase type I activity
OP863_01440	COG0009	L-threonylcarbamoyladenylate synthase
OP863_01445	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OP863_01450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OP863_01480	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OP863_01485	COG3162	membrane
OP863_01490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OP863_01495	COG1301	dicarboxylic acid transport
OP863_01660	COG2391	methyltransferase activity
OP863_01665	COG0425	Belongs to the sulfur carrier protein TusA family
OP863_01670	COG3264	Mechanosensitive ion channel
OP863_01670	COG1511	domain protein
OP863_01675	COG4774	siderophore transport
OP863_01685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP863_01690	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
OP863_01695	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP863_01700	COG4558	Periplasmic binding protein
OP863_01705	COG3720	iron ion transport
OP863_01770	COG2378	regulation of single-species biofilm formation
OP863_01785	COG3596	GTP binding
OP863_01840	COG3318	Belongs to the UPF0149 family
OP863_01840	COG3012	SEC-C Motif Domain Protein
OP863_01845	COG3547	Transposase (IS116 IS110 IS902 family)
OP863_01875	COG0288	reversible hydration of carbon dioxide
OP863_01895	COG0582	viral genome integration into host DNA
OP863_01905	COG1309	transcriptional regulator
OP863_01915	COG2084	Dehydrogenase
OP863_01920	COG1929	Belongs to the glycerate kinase type-1 family
OP863_01925	COG3835	regulator
OP863_01930	COG2721	sulfolactate sulfo-lyase activity
OP863_01935	COG2271	Major facilitator Superfamily
OP863_01940	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OP863_01940	COG0493	'glutamate synthase
OP863_01945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OP863_01950	COG3383	formate dehydrogenase (NAD+) activity
OP863_01955	COG4232	protein-disulfide reductase activity
OP863_01965	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OP863_01980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OP863_01985	COG0459	protein refolding
OP863_02000	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OP863_02020	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
OP863_02025	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
OP863_02030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OP863_02035	COG1053	succinate dehydrogenase
OP863_02040	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
OP863_02045	COG3264	Mechanosensitive ion channel
OP863_02045	COG1511	domain protein
OP863_02050	COG0688	phosphatidylethanolamine metabolic process
OP863_02055	COG1162	GTPase activity
OP863_02060	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OP863_02080	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
OP863_02085	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OP863_02085	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OP863_02090	COG0802	atpase or kinase
OP863_02095	COG0860	N-Acetylmuramoyl-L-alanine amidase
OP863_02100	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OP863_02105	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OP863_02115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OP863_02120	COG0330	HflC and HflK could
OP863_02125	COG0330	HflC and HflK could
OP863_02130	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
OP863_02135	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OP863_02140	COG1959	2 iron, 2 sulfur cluster binding
OP863_02145	COG0557	exoribonuclease II activity
OP863_02150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OP863_02155	COG1960	acyl-CoA dehydrogenase activity
OP863_02160	COG3650	response to hydrogen peroxide
OP863_02165	COG1073	alpha beta
OP863_02175	COG0360	Binds together with S18 to 16S ribosomal RNA
OP863_02180	COG2965	DNA replication, synthesis of RNA primer
OP863_02185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OP863_02190	COG0359	binds to the 23S rRNA
OP863_02200	COG3061	Opacity-associated protein A
OP863_02205	COG0545	Peptidyl-prolyl cis-trans isomerase
OP863_02215	COG0737	Belongs to the 5'-nucleotidase family
OP863_02220	COG1218	3'(2'),5'-bisphosphate nucleotidase
OP863_02225	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
OP863_02235	COG1253	flavin adenine dinucleotide binding
OP863_02240	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OP863_02245	COG0729	surface antigen
OP863_02250	COG2911	Protein conserved in bacteria
OP863_02255	COG2105	PFAM AIG2 family protein
OP863_02260	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OP863_02265	COG0840	transmembrane signaling receptor activity
OP863_02270	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OP863_02275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OP863_02290	COG1438	arginine binding
OP863_02295	COG0039	L-malate dehydrogenase activity
OP863_02300	COG3423	Transcriptional regulator
OP863_02310	COG0142	geranyltranstransferase activity
OP863_02325	COG0697	spore germination
OP863_02330	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OP863_02335	COG0642	Histidine kinase
OP863_02340	COG0745	RESPONSE REGULATOR receiver
OP863_02345	COG2027	D-alanyl-D-alanine carboxypeptidase
OP863_02355	COG1534	Rna-binding protein
OP863_02360	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OP863_02370	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OP863_02380	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OP863_02395	COG0779	Required for maturation of 30S ribosomal subunits
OP863_02400	COG0195	Participates in both transcription termination and antitermination
OP863_02405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OP863_02410	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OP863_02415	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OP863_02425	COG1185	polyribonucleotide nucleotidyltransferase activity
OP863_02435	COG0513	Belongs to the DEAD box helicase family
OP863_02440	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OP863_02445	COG0826	peptidase U32
OP863_02450	COG0826	peptidase U32
OP863_02455	COG3154	lipid carrier protein
OP863_02460	COG3153	acetyltransferase
OP863_02465	COG2827	Endonuclease containing a URI domain
OP863_02470	COG0531	amino acid
OP863_02475	COG1982	Orn Lys Arg decarboxylase major
OP863_02495	COG1653	transport
OP863_02500	COG1175	transmembrane transport
OP863_02505	COG0395	ABC-type sugar transport system, permease component
OP863_02510	COG3842	ATPase activity
OP863_02520	COG3787	Belongs to the UPF0306 family
OP863_02525	COG0702	epimerase
OP863_02530	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
OP863_02535	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
OP863_02540	COG3454	Phosphonate metabolism
OP863_02545	COG4778	phosphonate C-P lyase system protein PhnL
OP863_02550	COG4107	phosphonate C-P lyase system protein PhnK
OP863_02555	COG3627	carbon phosphorus lyase activity
OP863_02560	COG3626	phosphonate metabolism
OP863_02565	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
OP863_02570	COG3624	Phosphonate C-P lyase system protein PhnG
OP863_02575	COG2188	Transcriptional regulator
OP863_02590	COG4608	Belongs to the ABC transporter superfamily
OP863_02595	COG0444	Belongs to the ABC transporter superfamily
OP863_02600	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OP863_02605	COG0601	transmembrane transport
OP863_02615	COG2731	YhcH YjgK YiaL family protein
OP863_02625	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
OP863_02640	COG2927	DNA polymerase III (CHI subunit)
OP863_02645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OP863_02650	COG0795	lipopolysaccharide-transporting ATPase activity
OP863_02655	COG0795	lipopolysaccharide-transporting ATPase activity
OP863_02665	COG0582	viral genome integration into host DNA
OP863_02670	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OP863_02690	COG1401	restriction endodeoxyribonuclease activity
OP863_02700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OP863_02795	COG0583	DNA-binding transcription factor activity
OP863_02805	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
OP863_02815	COG1301	dicarboxylic acid transport
OP863_02820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OP863_02830	COG2831	hemolysin activation secretion protein
OP863_02865	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OP863_02870	COG1830	Aldolase
OP863_02875	COG1879	ABC-type sugar transport system periplasmic component
OP863_02880	COG1172	Belongs to the binding-protein-dependent transport system permease family
OP863_02885	COG1172	Belongs to the binding-protein-dependent transport system permease family
OP863_02890	COG1129	ABC transporter
OP863_02895	COG2390	Transcriptional regulator
OP863_02900	COG1070	Carbohydrate kinase
OP863_02905	COG0859	PFAM glycosyl transferase family 9
OP863_02920	COG2235	arginine
OP863_02925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP863_02930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OP863_02940	COG2376	Dihydroxyacetone kinase
OP863_02945	COG1461	Dihydroxyacetone kinase
OP863_02950	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
OP863_02950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP863_02950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OP863_02960	COG2192	nodulation
OP863_02985	COG3284	Transcriptional regulator
OP863_03015	COG0583	DNA-binding transcription factor activity
OP863_03020	COG0667	Aldo Keto reductase
OP863_03025	COG2813	Specifically methylates the guanine in position
OP863_03030	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
OP863_03035	COG0456	acetyltransferase
OP863_03040	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OP863_03045	COG2823	Periplasmic or secreted lipoprotein
OP863_03055	COG4667	esterase of the alpha-beta hydrolase superfamily
OP863_03060	COG0084	hydrolase, TatD family'
OP863_03065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OP863_03075	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OP863_03080	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OP863_03090	COG3726	membrane protein affecting hemolysin expression
OP863_03095	COG0560	Phosphoserine phosphatase
OP863_03120	COG0604	alcohol dehydrogenase
OP863_03130	COG0488	(ABC) transporter
OP863_03135	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OP863_03140	COG0741	lytic transglycosylase activity
OP863_03145	COG2973	This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region
OP863_03150	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
OP863_03160	COG3708	Transcriptional regulator
OP863_03160	COG2207	Transcriptional regulator
OP863_03165	COG3045	CreA protein
OP863_03170	COG0745	RESPONSE REGULATOR receiver
OP863_03190	COG0083	homoserine kinase activity
OP863_03200	COG3022	response to hydroperoxide
OP863_03205	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OP863_03210	COG0521	Mo-molybdopterin cofactor biosynthetic process
OP863_03215	COG0477	Major facilitator Superfamily
OP863_03225	COG1584	GPR1 FUN34 yaaH family protein
OP863_03235	COG0484	heat shock protein binding
OP863_03240	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OP863_03245	COG0583	DNA-binding transcription factor activity
OP863_03255	COG0196	riboflavin kinase activity
OP863_03260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OP863_03265	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OP863_03270	COG1047	Peptidyl-prolyl cis-trans
OP863_03275	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OP863_03280	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OP863_03290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OP863_03295	COG1280	lysine exporter protein (LysE YggA)
OP863_03300	COG2966	Psort location CytoplasmicMembrane, score
OP863_03310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
OP863_03325	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OP863_03330	COG2967	ApaG domain
OP863_03340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OP863_03350	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OP863_03360	COG0564	pseudouridine synthase activity
OP863_03365	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OP863_03370	COG0417	DNA replication proofreading
OP863_03375	COG0586	Pfam SNARE associated Golgi protein
OP863_03385	COG1178	ABC-type Fe3 transport system permease component
OP863_03390	COG4143	(ABC) transporter
OP863_03395	COG4533	DNA binding
OP863_03400	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OP863_03405	COG1882	Formate acetyltransferase
OP863_03410	COG3077	Addiction module antitoxin, RelB DinJ family
OP863_03420	COG2814	Major facilitator Superfamily
OP863_03425	COG3033	Beta-eliminating lyase
OP863_03440	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OP863_03445	COG0473	3-isopropylmalate dehydrogenase activity
OP863_03450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OP863_03460	COG1022	Amp-dependent synthetase and ligase
OP863_03465	COG0028	Belongs to the TPP enzyme family
OP863_03485	COG2001	Belongs to the MraZ family
OP863_03490	COG0275	rRNA processing
OP863_03495	COG3116	cell division
OP863_03500	COG0768	penicillin binding
OP863_03505	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OP863_03510	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OP863_03525	COG0772	Belongs to the SEDS family
OP863_03530	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OP863_03535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OP863_03545	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OP863_03550	COG0849	cell division
OP863_03555	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OP863_03575	COG0653	protein targeting
OP863_03580	COG0494	nUDIX hydrolase
OP863_03585	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OP863_03600	COG0516	GMP reductase activity
OP863_03605	COG1459	type II secretion system
OP863_03610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OP863_03615	COG4969	Belongs to the N-Me-Phe pilin family
OP863_03630	COG3725	Membrane protein required for beta-lactamase induction
OP863_03635	COG1113	amino acid transport
OP863_03640	COG2186	Transcriptional regulator
OP863_03645	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OP863_03650	COG0508	dehydrogenase complex catalyzes the overall conversion of
OP863_03655	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OP863_03665	COG4977	sequence-specific DNA binding
OP863_03675	COG1049	propionate catabolic process, 2-methylcitrate cycle
OP863_03680	COG3112	Uncharacterised protein family (UPF0231)
OP863_03685	COG0697	spore germination
OP863_03690	COG3210	domain, Protein
OP863_03690	COG3210	domain, Protein
OP863_03715	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
OP863_03720	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
OP863_03730	COG2132	Multicopper oxidase
OP863_03740	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
OP863_03745	COG0288	reversible hydration of carbon dioxide
OP863_03750	COG1131	(ABC) transporter
OP863_03755	COG0842	Transport permease protein
OP863_03760	COG0726	polysaccharide deacetylase
OP863_03765	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
OP863_03770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OP863_03775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OP863_03780	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OP863_03785	COG0617	tRNA 3'-terminal CCA addition
OP863_03800	COG1489	DNA binding
OP863_03805	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
OP863_03810	COG1643	Atp-dependent helicase
OP863_03815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OP863_03820	COG1120	ATPase activity
OP863_03825	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OP863_03830	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP863_03835	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OP863_03845	COG0316	Belongs to the HesB IscA family
OP863_03855	COG2860	membrane
OP863_03865	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OP863_03870	COG0232	Belongs to the dGTPase family. Type 2 subfamily
OP863_03875	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OP863_03880	COG2205	protein histidine kinase activity
OP863_03880	COG3437	response regulator, receiver
OP863_03880	COG3850	Histidine kinase
OP863_03880	COG4999	Histidine kinase
OP863_03885	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OP863_03890	COG3956	TIGRFAM MazG family protein
OP863_03895	COG0504	CTP synthase activity
OP863_03900	COG0148	phosphopyruvate hydratase activity
OP863_03930	COG0602	queuosine metabolic process
OP863_03935	COG0720	synthase
OP863_03940	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OP863_03945	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OP863_03950	COG0175	sulfate reduction
OP863_03965	COG2234	aminopeptidase activity
OP863_03970	COG1648	precorrin-2 dehydrogenase activity
OP863_03970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OP863_03975	COG0175	sulfate reduction
OP863_03980	COG2895	sulfate adenylyltransferase (ATP) activity
OP863_03985	COG0529	Catalyzes the synthesis of activated sulfate
OP863_04000	COG0765	amino acid transport
OP863_04010	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OP863_04020	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
OP863_04025	COG0585	pseudouridine synthase activity
OP863_04030	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OP863_04035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OP863_04040	COG1388	LysM domain
OP863_04040	COG4942	peptidase
OP863_04045	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OP863_04050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OP863_04075	COG3188	usher protein
OP863_04080	COG3121	Chaperone
OP863_04095	COG3539	Fimbrial protein
OP863_04100	COG3539	Fimbrial protein
OP863_04130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP863_04135	COG0577	efflux transmembrane transporter activity
OP863_04135	COG1136	(ABC) transporter
OP863_04140	COG1538	Outer membrane efflux protein
OP863_04160	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_04170	COG1858	cytochrome C peroxidase
OP863_04175	COG3158	transport of potassium into the cell
OP863_04180	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OP863_04185	COG0640	Transcriptional regulator
OP863_04245	COG0410	ABC transporter
OP863_04250	COG1137	ATPase activity
OP863_04255	COG4177	L-phenylalanine transmembrane transporter activity
OP863_04270	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
OP863_04270	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
OP863_04275	COG0243	molybdopterin cofactor binding
OP863_04280	COG0437	4 iron, 4 sulfur cluster binding
OP863_04285	COG3302	dmso reductase anchor subunit
OP863_04290	COG3381	protein complex oligomerization
OP863_04305	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OP863_04310	COG2137	regulation of response to DNA damage stimulus
OP863_04315	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OP863_04320	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OP863_04345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OP863_04350	COG1238	metal cluster binding
OP863_04355	COG2918	glutathione biosynthetic process
OP863_04360	COG1854	S-ribosylhomocysteine lyase activity
OP863_04365	COG4536	flavin adenine dinucleotide binding
OP863_04370	COG4137	Cytochrome C assembly protein
OP863_04375	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OP863_04385	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OP863_04390	COG0336	Belongs to the RNA methyltransferase TrmD family
OP863_04395	COG0335	large ribosomal subunit rRNA binding
OP863_04400	COG3137	Salt-induced outer membrane protein
OP863_04405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OP863_04410	COG3279	Response regulator of the LytR AlgR family
OP863_04415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OP863_04420	COG0287	Prephenate dehydrogenase
OP863_04420	COG1605	Chorismate mutase
OP863_04425	COG0077	Prephenate dehydratase
OP863_04425	COG1605	Chorismate mutase
OP863_04430	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OP863_04435	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OP863_04440	COG0564	pseudouridine synthase activity
OP863_04445	COG1496	oxidoreductase activity
OP863_04450	COG0542	response to heat
OP863_04480	COG0656	L-ascorbic acid biosynthetic process
OP863_04485	COG0583	DNA-binding transcription factor activity
OP863_04490	COG2814	Major facilitator Superfamily
OP863_04495	COG3021	interspecies interaction between organisms
OP863_04500	COG1388	LysM domain
OP863_04500	COG0741	lytic transglycosylase activity
OP863_04505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OP863_04510	COG2226	methyltransferase
OP863_04515	COG0328	RNA-DNA hybrid ribonuclease activity
OP863_04520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OP863_04530	COG2113	Glycine betaine
OP863_04535	COG4176	ABC-type proline glycine betaine transport system permease component
OP863_04545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OP863_04555	COG1780	Probably involved in ribonucleotide reductase function
OP863_04560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OP863_04565	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OP863_04575	COG4575	ribosome binding
OP863_04605	COG1278	Cold shock
OP863_04625	COG0747	negative chemotaxis
OP863_04635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OP863_04645	COG1124	(ABC) transporter
OP863_04650	COG0831	urea catabolic process
OP863_04655	COG0832	Belongs to the urease beta subunit family
OP863_04660	COG0804	urea catabolic process
OP863_04665	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
OP863_04675	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OP863_04680	COG0829	nickel cation binding
OP863_04685	COG4413	Urea transporter
OP863_04690	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
OP863_04700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OP863_04715	COG0667	Aldo Keto reductase
OP863_04720	COG2133	pyrroloquinoline quinone binding
OP863_04730	COG3423	Transcriptional regulator
OP863_04735	COG2801	Transposase and inactivated derivatives
OP863_04740	COG2842	Transposition protein
OP863_04785	COG5566	PFAM Mor transcription activator
OP863_04820	COG0640	Transcriptional regulator
OP863_04835	COG4373	Mu-like prophage FluMu protein gp28
OP863_04840	COG4383	Mu-like prophage protein gp29
OP863_04845	COG2369	cell adhesion
OP863_04855	COG4388	Caudovirus prohead serine protease
OP863_04860	COG4397	Mu-like prophage major head subunit gpT
OP863_04870	COG4387	Mu-like prophage protein GP36
OP863_04875	COG5003	unkown
OP863_04885	COG4386	tail sheath protein
OP863_04895	COG4518	Phage tail assembly chaperone proteins, E, or 41 or 14
OP863_04905	COG4228	DNA circulation
OP863_04915	COG4384	Bacteriophage Mu Gp45 protein
OP863_04920	COG4381	Mu-like prophage protein gp46
OP863_04925	COG3299	homolog of phage Mu protein gp47
OP863_04930	COG3778	Protein conserved in bacteria
OP863_04935	COG5301	cellulose 1,4-beta-cellobiosidase activity
OP863_04945	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OP863_04950	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OP863_04955	COG2723	6-phospho-beta-galactosidase activity
OP863_04960	COG1447	Phosphotransferase system cellobiose-specific component IIA
OP863_04965	COG1917	Cupin 2, conserved barrel domain protein
OP863_04965	COG2169	Transcriptional regulator
OP863_04970	COG3394	polysaccharide catabolic process
OP863_04985	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OP863_04990	COG2867	negative regulation of translational initiation
OP863_05000	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OP863_05005	COG0497	DNA recombination
OP863_05010	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OP863_05015	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OP863_05020	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OP863_05025	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
OP863_05035	COG0513	Belongs to the DEAD box helicase family
OP863_05040	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OP863_05045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OP863_05055	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
OP863_05065	COG3086	response to oxidative stress
OP863_05075	COG0481	GTPase activity
OP863_05090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
OP863_05095	COG1381	Involved in DNA repair and RecF pathway recombination
OP863_05100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OP863_05105	COG0736	holo-[acyl-carrier-protein] synthase activity
OP863_05110	COG2610	gluconate transmembrane transporter activity
OP863_05115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OP863_05120	COG1737	Transcriptional regulator
OP863_05125	COG2771	luxR family
OP863_05130	COG3423	Transcriptional regulator
OP863_05140	COG0560	Phosphoserine phosphatase
OP863_05155	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OP863_05170	COG2205	protein histidine kinase activity
OP863_05175	COG3170	Tfp pilus assembly protein FimV
OP863_05180	COG2204	response regulator
OP863_05185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OP863_05185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OP863_05190	COG0347	Belongs to the P(II) protein family
OP863_05200	COG2188	Transcriptional regulator
OP863_05205	COG1017	nitric oxide dioxygenase activity
OP863_05205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OP863_05210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OP863_05215	COG2814	Major facilitator Superfamily
OP863_05220	COG3711	transcriptional antiterminator
OP863_05225	COG3683	transport system, periplasmic component
OP863_05230	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
OP863_05235	COG0483	inositol monophosphate 1-phosphatase activity
OP863_05240	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
OP863_05245	COG1959	2 iron, 2 sulfur cluster binding
OP863_05255	COG0822	iron-sulfur transferase activity
OP863_05265	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OP863_05270	COG0443	Heat shock 70 kDa protein
OP863_05275	COG0633	Ferredoxin
OP863_05280	COG2975	iron-sulfur cluster assembly
OP863_05295	COG3468	outer membrane autotransporter barrel domain protein
OP863_05300	COG2373	Large extracellular alpha-helical protein
OP863_05305	COG4953	penicillin-binding protein 1C
OP863_05320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OP863_05330	COG1426	Protein conserved in bacteria
OP863_05340	COG0124	histidyl-tRNA synthetase
OP863_05345	COG2976	Protein conserved in bacteria
OP863_05350	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OP863_05355	COG1160	GTP binding
OP863_05365	COG1645	bacterial-type flagellum-dependent swarming motility
OP863_05370	COG1570	exodeoxyribonuclease VII activity
OP863_05375	COG0517	IMP dehydrogenase activity
OP863_05375	COG0516	GMP reductase activity
OP863_05380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OP863_05380	COG0519	Catalyzes the synthesis of GMP from XMP
OP863_05405	COG0351	phosphomethylpyrimidine kinase
OP863_05425	COG1349	DNA-binding transcription factor activity
OP863_05430	COG4578	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP863_05435	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_05450	COG3730	PTS system glucitol sorbitol-specific
OP863_05455	COG1597	lipid kinase activity
OP863_05460	COG0826	peptidase U32
OP863_05465	COG3422	double-strand break repair
OP863_05470	COG0745	RESPONSE REGULATOR receiver
OP863_05475	COG2205	protein histidine kinase activity
OP863_05480	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OP863_05490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP863_05500	COG0443	Heat shock 70 kDa protein
OP863_05505	COG5001	Diguanylate cyclase
OP863_05505	COG5002	protein histidine kinase activity
OP863_05505	COG3447	MASE1 domain protein
OP863_05510	COG2239	Acts as a magnesium transporter
OP863_05525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OP863_05530	COG0573	inorganic phosphate transmembrane transporter activity
OP863_05535	COG0581	inorganic phosphate transmembrane transporter activity
OP863_05550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP863_05555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OP863_05560	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OP863_05565	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OP863_05570	COG2233	PERMEase
OP863_05575	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OP863_05580	COG1393	Belongs to the ArsC family
OP863_05585	COG4783	chaperone-mediated protein folding
OP863_05590	COG0628	permease
OP863_05595	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OP863_05600	COG2716	regulation of RNA biosynthetic process
OP863_05605	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OP863_05610	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
OP863_05615	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OP863_05620	COG2321	neutral zinc metallopeptidase
OP863_05625	COG2707	UPF0756 membrane protein
OP863_05630	COG1444	tRNA N-acetyltransferase activity
OP863_05635	COG0400	carboxylic ester hydrolase activity
OP863_05645	COG1876	peptidase activity
OP863_05650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OP863_05655	COG1393	Belongs to the ArsC family
OP863_05685	COG3842	ATPase activity
OP863_05690	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OP863_05700	COG2197	response regulator
OP863_05705	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OP863_05705	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
OP863_05710	COG3062	negative regulation of establishment of protein localization
OP863_05715	COG0243	molybdopterin cofactor binding
OP863_05720	COG3043	anaerobic respiration
OP863_05725	COG3005	denitrification pathway
OP863_05740	COG0494	nUDIX hydrolase
OP863_05750	COG1671	Belongs to the UPF0178 family
OP863_05755	COG0408	coproporphyrinogen oxidase activity
OP863_05760	COG0456	acetyltransferase
OP863_05765	COG3111	PFAM Bacterial OB fold (BOF) protein
OP863_05775	COG2837	iron assimilation
OP863_05780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OP863_05795	COG2731	YhcH YjgK YiaL family protein
OP863_05800	COG1737	Transcriptional regulator
OP863_05810	COG4150	thiosulfate binding
OP863_05815	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OP863_05820	COG4208	sulfate ABC transporter
OP863_05835	COG0745	RESPONSE REGULATOR receiver
OP863_05840	COG2205	protein histidine kinase activity
OP863_05850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OP863_05855	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP863_05875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OP863_05880	COG3530	Putative quorum-sensing-regulated virulence factor
OP863_05905	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OP863_05940	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OP863_05955	COG0667	Aldo Keto reductase
OP863_05965	COG0583	DNA-binding transcription factor activity
OP863_05975	COG0837	glucose binding
OP863_05980	COG2223	nitrite transmembrane transporter activity
OP863_05985	COG3279	Response regulator of the LytR AlgR family
OP863_05990	COG3275	phosphorelay sensor kinase activity
OP863_06005	COG0436	Aminotransferase
OP863_06010	COG3038	cytochrome b561
OP863_06030	COG3381	protein complex oligomerization
OP863_06035	COG3302	dmso reductase anchor subunit
OP863_06040	COG0437	4 iron, 4 sulfur cluster binding
OP863_06045	COG0243	molybdopterin cofactor binding
OP863_06055	COG1280	lysine exporter protein (LysE YggA)
OP863_06075	COG2951	lytic endotransglycosylase activity
OP863_06080	COG0531	amino acid
OP863_06100	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OP863_06105	COG1127	ABC transporter
OP863_06120	COG3038	cytochrome b561
OP863_06125	COG2353	YceI-like domain
OP863_06130	COG1609	Transcriptional regulator
OP863_06135	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP863_06135	COG1263	PTS System
OP863_06140	COG2723	6-phospho-beta-galactosidase activity
OP863_06160	COG2824	Alkylphosphonate utilization operon protein PhnA
OP863_06165	COG2850	peptidyl-arginine hydroxylation
OP863_06170	COG5265	(ABC) transporter
OP863_06195	COG2197	response regulator
OP863_06200	COG1278	Cold shock
OP863_06215	COG3706	GGDEF domain
OP863_06220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OP863_06225	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OP863_06230	COG0321	lipoyl(octanoyl) transferase activity
OP863_06235	COG2921	Belongs to the UPF0250 family
OP863_06240	COG1686	Belongs to the peptidase S11 family
OP863_06245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OP863_06250	COG0772	Belongs to the SEDS family
OP863_06255	COG0768	penicillin binding
OP863_06265	COG0799	negative regulation of ribosome biogenesis
OP863_06270	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OP863_06275	COG1466	dna polymerase III delta subunit
OP863_06280	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
OP863_06290	COG2888	peptidyl-tyrosine sulfation
OP863_06300	COG1126	abc transporter atp-binding protein
OP863_06305	COG0765	amino acid transport
OP863_06310	COG0765	amino acid transport
OP863_06325	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OP863_06330	COG4535	Mg2 and Co2 transporter CorC
OP863_06335	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OP863_06340	COG1702	phosphate starvation-inducible protein PhoH
OP863_06345	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OP863_06350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OP863_06385	COG0367	asparagine synthase
OP863_06390	COG0647	UMP catabolic process
OP863_06395	COG1940	carbohydrate kinase activity
OP863_06395	COG1846	Transcriptional regulator
OP863_06400	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OP863_06405	COG0363	glucosamine-6-phosphate deaminase activity
OP863_06410	COG1263	PTS System
OP863_06410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP863_06410	COG2190	(PTS) system
OP863_06415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OP863_06435	COG0735	belongs to the Fur family
OP863_06445	COG0840	transmembrane signaling receptor activity
OP863_06455	COG0596	Alpha beta hydrolase
OP863_06460	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
OP863_06465	COG0033	Phosphoglucomutase
OP863_06485	COG0745	RESPONSE REGULATOR receiver
OP863_06490	COG2205	protein histidine kinase activity
OP863_06495	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
OP863_06500	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
OP863_06505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
OP863_06525	COG2994	toxin metabolic process
OP863_06530	COG3064	Membrane
OP863_06530	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
OP863_06530	COG1073	alpha beta
OP863_06530	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
OP863_06530	COG1073	alpha beta
OP863_06530	COG3064	Membrane
OP863_06535	COG3272	Protein of unknown function (DUF1722)
OP863_06545	COG5212	phosphodiesterase
OP863_06550	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OP863_06555	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
OP863_06560	COG1984	allophanate hydrolase subunit 2
OP863_06565	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
OP863_06580	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
OP863_06590	COG2009	succinate dehydrogenase
OP863_06595	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OP863_06600	COG1053	succinate dehydrogenase
OP863_06610	COG0567	Dehydrogenase, E1 component
OP863_06615	COG0508	dehydrogenase complex catalyzes the overall conversion of
OP863_06625	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OP863_06630	COG0737	Belongs to the 5'-nucleotidase family
OP863_06635	COG1271	oxidase subunit
OP863_06640	COG1294	oxidase, subunit
OP863_06645	COG4890	Cyd operon protein YbgT
OP863_06650	COG3790	cyd operon protein YbgE
OP863_06655	COG0824	Thioesterase
OP863_06660	COG0811	peptide transport
OP863_06665	COG0848	biopolymer transport protein
OP863_06670	COG3064	Membrane
OP863_06670	COG3064	Membrane
OP863_06675	COG0823	Involved in the tonB-independent uptake of proteins
OP863_06680	COG2885	chlorophyll binding
OP863_06685	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
OP863_06740	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OP863_06750	COG1230	cation diffusion facilitator family transporter
OP863_06755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OP863_06760	COG0588	phosphoglycerate mutase activity
OP863_06770	COG2017	converts alpha-aldose to the beta-anomer
OP863_06775	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OP863_06785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OP863_06795	COG1119	ATPase activity
OP863_06800	COG2005	Transcriptional regulator
OP863_06800	COG3585	molybdate ion transport
OP863_06810	COG0725	ABC transporter, periplasmic molybdate-binding protein
OP863_06815	COG4149	molybdate abc transporter
OP863_06825	COG0561	phosphatase activity
OP863_06830	COG2706	6-phosphogluconolactonase activity
OP863_06840	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OP863_06845	COG0156	8-amino-7-oxononanoate synthase activity
OP863_06850	COG2226	methyltransferase
OP863_06865	COG0556	nucleotide-excision repair
OP863_06870	COG4628	conserved protein (DUF2132)
OP863_06875	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OP863_06880	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OP863_06885	COG0315	cyclic pyranopterin monophosphate synthase activity
OP863_06890	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OP863_06895	COG0314	molybdopterin synthase activity
OP863_06900	COG0670	Belongs to the BI1 family
OP863_06905	COG0842	Transport permease protein
OP863_06910	COG0842	Transport permease protein
OP863_06915	COG1131	(ABC) transporter
OP863_06920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP863_06925	COG1309	transcriptional regulator
OP863_06930	COG0513	Belongs to the DEAD box helicase family
OP863_06935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OP863_06945	COG2239	Acts as a magnesium transporter
OP863_06955	COG1686	Belongs to the peptidase S11 family
OP863_06960	COG0277	FAD linked oxidase domain protein
OP863_06980	COG2261	transglycosylase associated protein
OP863_06990	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
OP863_07005	COG4807	Protein conserved in bacteria
OP863_07010	COG2897	thiosulfate sulfurtransferase activity
OP863_07025	COG1732	Glycine betaine
OP863_07030	COG1174	glycine betaine transport
OP863_07035	COG1125	glycine betaine transport
OP863_07040	COG1174	glycine betaine transport
OP863_07055	COG0697	spore germination
OP863_07070	COG1199	ATP-dependent helicase activity
OP863_07075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OP863_07080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OP863_07095	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
OP863_07105	COG1126	abc transporter atp-binding protein
OP863_07110	COG0765	amino acid transport
OP863_07115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP863_07120	COG0783	Belongs to the Dps family
OP863_07125	COG4106	trans-aconitate 2-methyltransferase activity
OP863_07140	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
OP863_07155	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
OP863_07165	COG0488	(ABC) transporter
OP863_07175	COG0303	'Molybdopterin
OP863_07190	COG0577	efflux transmembrane transporter activity
OP863_07190	COG1136	(ABC) transporter
OP863_07220	COG0583	DNA-binding transcription factor activity
OP863_07225	COG0477	Major facilitator Superfamily
OP863_07230	COG0302	gtp cyclohydrolase
OP863_07235	COG2311	Membrane
OP863_07260	COG2116	formate transmembrane transporter activity
OP863_07265	COG3604	Transcriptional regulator
OP863_07270	COG3383	formate dehydrogenase (NAD+) activity
OP863_07275	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OP863_07280	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OP863_07290	COG3260	NADH ubiquinone oxidoreductase 20
OP863_07295	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OP863_07300	COG3261	NADH dehydrogenase
OP863_07300	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
OP863_07305	COG0651	ATP synthesis coupled electron transport
OP863_07310	COG4237	Hydrogenase 4 membrane
OP863_07315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OP863_07320	COG0650	Formate hydrogenlyase subunit 4
OP863_07325	COG0651	ATP synthesis coupled electron transport
OP863_07330	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
OP863_07335	COG0375	protein maturation
OP863_07340	COG0298	carbon dioxide binding
OP863_07345	COG2949	membrane
OP863_07350	COG0281	malic enzyme
OP863_07365	COG1346	cytolysis
OP863_07370	COG1380	Effector of murein hydrolase LrgA
OP863_07375	COG2814	Major facilitator Superfamily
OP863_07395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OP863_07395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OP863_07400	COG0489	protein tyrosine kinase activity
OP863_07405	COG0572	uridine kinase
OP863_07410	COG0717	Belongs to the dCTP deaminase family
OP863_07415	COG2982	Protein involved in outer membrane biogenesis
OP863_07420	COG3069	C4-dicarboxylate transmembrane transporter activity
OP863_07425	COG1253	flavin adenine dinucleotide binding
OP863_07435	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OP863_07440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OP863_07450	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OP863_07450	COG0140	phosphoribosyl-ATP diphosphatase activity
OP863_07455	COG0107	imidazoleglycerol-phosphate synthase activity
OP863_07460	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OP863_07470	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OP863_07470	COG0131	Imidazoleglycerol-phosphate dehydratase
OP863_07475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OP863_07485	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OP863_07495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP863_07500	COG1172	Belongs to the binding-protein-dependent transport system permease family
OP863_07505	COG1129	ABC transporter
OP863_07510	COG0371	Dehydrogenase
OP863_07515	COG0531	amino acid
OP863_07520	COG2925	Exonuclease
OP863_07525	COG3320	Male sterility
OP863_07525	COG1022	Amp-dependent synthetase and ligase
OP863_07530	COG1289	transmembrane transporter activity
OP863_07545	COG1172	Belongs to the binding-protein-dependent transport system permease family
OP863_07550	COG1129	ABC transporter
OP863_07565	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OP863_07570	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OP863_07570	COG1648	precorrin-2 dehydrogenase activity
OP863_07575	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OP863_07595	COG4656	Part of a membrane complex involved in electron transport
OP863_07605	COG1012	belongs to the aldehyde dehydrogenase family
OP863_07615	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
OP863_07690	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
OP863_07700	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
OP863_07765	COG1492	cobalamin metabolic process
OP863_07785	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
OP863_07790	COG0583	DNA-binding transcription factor activity
OP863_07800	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
OP863_07805	COG2211	Major facilitator Superfamily
OP863_07810	COG0137	argininosuccinate synthase activity
OP863_07815	COG0534	Mate efflux family protein
OP863_07825	COG0352	thiamine-phosphate diphosphorylase activity
OP863_07830	COG0561	phosphatase activity
OP863_07835	COG1349	DNA-binding transcription factor activity
OP863_07850	COG0583	DNA-binding transcription factor activity
OP863_07855	COG0784	Response regulator, receiver
OP863_07855	COG0835	chemotaxis
OP863_07870	COG3121	Chaperone
OP863_07885	COG3121	Chaperone
OP863_07895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP863_07895	COG2205	protein histidine kinase activity
OP863_07910	COG3842	ATPase activity
OP863_07920	COG1840	ABC-type Fe3 transport system, periplasmic component
OP863_07925	COG2271	Major facilitator Superfamily
OP863_07940	COG4565	transcriptional regulatory protein
OP863_07945	COG3290	protein histidine kinase activity
OP863_07950	COG3053	Acetylation of prosthetic group (2-(5''-phosphoribosyl)- 3'-dephosphocoenzyme-A) of the gamma subunit of citrate lyase
OP863_07955	COG3052	prosthetic group binding
OP863_07960	COG2301	Belongs to the HpcH HpaI aldolase family
OP863_07965	COG3051	citrate lyase alpha subunit
OP863_07970	COG3697	Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase
OP863_07970	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
OP863_07980	COG0471	metal ion transport
OP863_07995	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
OP863_08030	COG3228	Belongs to the MtfA family
OP863_08050	COG3121	Chaperone
OP863_08055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OP863_08060	COG4589	Belongs to the CDS family
OP863_08070	COG2267	carboxylic ester hydrolase activity
OP863_08075	COG0671	phosphoesterase, PA-phosphatase related
OP863_08075	COG2453	phosphatase
OP863_08085	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
OP863_08115	COG0604	alcohol dehydrogenase
OP863_08115	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_08115	COG3321	synthase
OP863_08120	COG3250	beta-galactosidase activity
OP863_08125	COG1609	Transcriptional regulator
OP863_08140	COG0840	transmembrane signaling receptor activity
OP863_08145	COG1285	pathogenesis
OP863_08160	COG0589	response to stress
OP863_08180	COG1360	Flagellar Motor Protein
OP863_08185	COG0643	Histidine kinase
OP863_08185	COG2198	Histidine kinase
OP863_08190	COG0835	chemotaxis
OP863_08195	COG0840	transmembrane signaling receptor activity
OP863_08200	COG0840	transmembrane signaling receptor activity
OP863_08205	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OP863_08215	COG0745	RESPONSE REGULATOR receiver
OP863_08220	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
OP863_08225	COG1404	Belongs to the peptidase S8 family
OP863_08225	COG4935	Belongs to the peptidase S8 family
OP863_08230	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OP863_08235	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OP863_08245	COG3418	PFAM FlgN family protein
OP863_08250	COG2747	anti-sigma28 factor FlgM
OP863_08260	COG1815	bacterial-type flagellum-dependent cell motility
OP863_08265	COG1558	bacterial-type flagellum-dependent cell motility
OP863_08270	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
OP863_08305	COG1256	bacterial-type flagellum assembly
OP863_08345	COG1580	Controls the rotational direction of flagella during chemotaxis
OP863_08365	COG1317	bacterial-type flagellum organization
OP863_08380	COG1677	Flagellar hook-basal body complex protein FliE
OP863_08390	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
OP863_08395	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OP863_08425	COG1191	sigma factor activity
OP863_08435	COG2515	1-aminocyclopropane-1-carboxylate deaminase
OP863_08440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP863_08445	COG0765	amino acid transport
OP863_08450	COG1126	abc transporter atp-binding protein
OP863_08465	COG0506	proline dehydrogenase activity
OP863_08465	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OP863_08465	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OP863_08475	COG0672	)-iron permease
OP863_08490	COG0655	NAD(P)H dehydrogenase (quinone) activity
OP863_08500	COG3055	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses
OP863_08505	COG1113	amino acid transport
OP863_08545	COG2246	polysaccharide biosynthetic process
OP863_08580	COG0366	Alpha amylase catalytic
OP863_08590	COG3136	membrane protein required for alginate biosynthesis
OP863_08600	COG2197	response regulator
OP863_08605	COG0322	excinuclease ABC activity
OP863_08610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OP863_08660	COG3493	citrate carrier protein
OP863_08665	COG4565	transcriptional regulatory protein
OP863_08670	COG3290	protein histidine kinase activity
OP863_08685	COG3622	Belongs to the hyi family
OP863_08690	COG2066	Belongs to the glutaminase family
OP863_08710	COG0672	)-iron permease
OP863_08725	COG0577	efflux transmembrane transporter activity
OP863_08725	COG1136	(ABC) transporter
OP863_08735	COG0577	efflux transmembrane transporter activity
OP863_08735	COG1136	(ABC) transporter
OP863_08760	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OP863_08765	COG4114	ferric iron reductase
OP863_08770	COG0006	proline dipeptidase activity
OP863_08775	COG0457	Tetratricopeptide repeat
OP863_08780	COG0726	polysaccharide deacetylase
OP863_08780	COG1649	PFAM Uncharacterised BCR, COG1649
OP863_08785	COG1215	transferase activity, transferring glycosyl groups
OP863_08790	COG3658	cytochrome
OP863_08800	COG1702	phosphate starvation-inducible protein PhoH
OP863_08805	COG0387	Pfam Sodium calcium exchanger
OP863_08815	COG0583	DNA-binding transcription factor activity
OP863_08820	COG3850	Histidine kinase
OP863_08830	COG1294	oxidase, subunit
OP863_08835	COG1271	oxidase subunit
OP863_08840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP863_08845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OP863_08850	COG3138	arginine N-succinyltransferase
OP863_08860	COG3724	N-succinylarginine dihydrolase activity
OP863_08865	COG2988	succinylglutamate desuccinylase activity
OP863_08880	COG1228	amidohydrolase
OP863_08890	COG0402	S-adenosylhomocysteine deaminase activity
OP863_08905	COG1129	ABC transporter
OP863_08910	COG4211	Belongs to the binding-protein-dependent transport system permease family
OP863_08915	COG3443	Belongs to the bacterial solute-binding protein 9 family
OP863_08925	COG4942	peptidase
OP863_08930	COG0012	GTP binding
OP863_08940	COG0193	aminoacyl-tRNA hydrolase activity
OP863_08950	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OP863_08960	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OP863_08965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OP863_08970	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OP863_08975	COG2890	protein-(glutamine-N5) methyltransferase activity
OP863_08990	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OP863_08995	COG0659	secondary active sulfate transmembrane transporter activity
OP863_09025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OP863_09030	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OP863_09035	COG3381	protein complex oligomerization
OP863_09045	COG0477	Major facilitator Superfamily
OP863_09050	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP863_09060	COG0673	inositol 2-dehydrogenase activity
OP863_09065	COG0728	peptidoglycan biosynthetic process
OP863_09070	COG0018	arginyl-trna synthetase
OP863_09075	COG3102	Protein conserved in bacteria
OP863_09080	COG3142	Participates in the control of copper homeostasis
OP863_09085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OP863_09090	COG2226	methyltransferase
OP863_09095	COG3788	relative of glutathione S-transferase, MAPEG superfamily
OP863_09100	COG1801	Protein of unknown function DUF72
OP863_09105	COG1335	isochorismatase
OP863_09110	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OP863_09115	COG0494	nUDIX hydrolase
OP863_09120	COG0217	transcriptional regulatory protein
OP863_09125	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OP863_09130	COG0632	four-way junction helicase activity
OP863_09135	COG2255	four-way junction helicase activity
OP863_09140	COG3104	oligopeptide transport
OP863_09145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OP863_09150	COG1121	(ABC) transporter
OP863_09155	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
OP863_09160	COG0739	heme binding
OP863_09165	COG1560	Kdo2-lipid A biosynthetic process
OP863_09170	COG0469	pyruvate kinase activity
OP863_09175	COG1737	Transcriptional regulator
OP863_09180	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
OP863_09185	COG0800	Aldolase
OP863_09190	COG2076	Multidrug Resistance protein
OP863_09195	COG2076	Multidrug Resistance protein
OP863_09200	COG0251	oxidation-reduction process
OP863_09205	COG1199	ATP-dependent helicase activity
OP863_09215	COG3065	identical protein binding
OP863_09220	COG0318	PFAM AMP-dependent synthetase and ligase
OP863_09225	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
OP863_09230	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OP863_09235	COG2894	cell division
OP863_09240	COG0850	regulation of cytokinetic process
OP863_09250	COG3100	YcgL domain-containing protein
OP863_09255	COG2951	lytic endotransglycosylase activity
OP863_09260	COG0179	Fumarylacetoacetate (FAA) hydrolase
OP863_09265	COG2983	Belongs to the UPF0260 family
OP863_09280	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OP863_09285	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OP863_09290	COG2186	Transcriptional regulator
OP863_09295	COG2719	SpoVR family
OP863_09300	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OP863_09305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OP863_09310	COG2814	Major facilitator Superfamily
OP863_09315	COG2199	diguanylate cyclase activity
OP863_09315	COG2200	EAL domain
OP863_09315	COG2202	Pas domain
OP863_09325	COG0583	DNA-binding transcription factor activity
OP863_09335	COG2718	Belongs to the UPF0229 family
OP863_09340	COG2766	serine protein kinase
OP863_09345	COG3713	MltA-interacting MipA family protein
OP863_09360	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OP863_09365	COG3139	Protein of unknown function (DUF1315)
OP863_09370	COG1335	isochorismatase
OP863_09375	COG0252	asparaginase activity
OP863_09380	COG0616	signal peptide processing
OP863_09385	COG0778	Nitroreductase
OP863_09395	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OP863_09405	COG0494	nUDIX hydrolase
OP863_09410	COG0708	Exodeoxyribonuclease III
OP863_09415	COG0583	DNA-binding transcription factor activity
OP863_09435	COG0788	formyltetrahydrofolate deformylase activity
OP863_09440	COG3012	SEC-C Motif Domain Protein
OP863_09450	COG1752	Esterase of the alpha-beta hydrolase superfamily
OP863_09455	COG0745	RESPONSE REGULATOR receiver
OP863_09465	COG2916	Histone family protein nucleoid-structuring protein H-NS
OP863_09475	COG1012	belongs to the aldehyde dehydrogenase family
OP863_09475	COG1454	alcohol dehydrogenase
OP863_09480	COG2095	MarC family integral membrane protein
OP863_09500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OP863_09505	COG0444	Belongs to the ABC transporter superfamily
OP863_09510	COG4608	Belongs to the ABC transporter superfamily
OP863_09515	COG3099	Belongs to the UPF0263 family
OP863_09520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OP863_09530	COG2200	EAL domain
OP863_09545	COG2350	Protein conserved in bacteria
OP863_09550	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
OP863_09560	COG2917	probably involved in intracellular septation
OP863_09575	COG3047	cAMP biosynthetic process
OP863_09585	COG0159	tryptophan synthase activity
OP863_09590	COG0133	tryptophan synthase activity
OP863_09595	COG0134	indole-3-glycerol-phosphate synthase activity
OP863_09595	COG0135	phosphoribosylanthranilate isomerase activity
OP863_09610	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OP863_09615	COG0613	PHP domain protein
OP863_09620	COG0009	L-threonylcarbamoyladenylate synthase
OP863_09645	COG1388	LysM domain
OP863_09645	COG2373	Large extracellular alpha-helical protein
OP863_09645	COG4932	domain protein
OP863_09675	COG1187	pseudouridine synthase activity
OP863_09685	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
OP863_09690	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_09695	COG0616	signal peptide processing
OP863_09710	COG0583	DNA-binding transcription factor activity
OP863_09735	COG0671	phosphoesterase, PA-phosphatase related
OP863_09740	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
OP863_09745	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OP863_09760	COG0284	orotidine-5'-phosphate decarboxylase activity
OP863_09765	COG0023	Translation Initiation Factor
OP863_09775	COG0235	Class ii aldolase
OP863_09785	COG1349	DNA-binding transcription factor activity
OP863_09790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OP863_09795	COG2879	small protein
OP863_09800	COG1966	Carbon starvation protein
OP863_09805	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
OP863_09810	COG0243	molybdopterin cofactor binding
OP863_09830	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OP863_09840	COG4659	FMN binding
OP863_09845	COG4658	electron transport chain
OP863_09850	COG3708	Transcriptional regulator
OP863_09850	COG2207	Transcriptional regulator
OP863_09855	COG4656	Part of a membrane complex involved in electron transport
OP863_09875	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OP863_09895	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
OP863_09900	COG2160	L-arabinose isomerase activity
OP863_09930	COG0673	inositol 2-dehydrogenase activity
OP863_09935	COG0385	Bile acid
OP863_09940	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OP863_09945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OP863_09950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP863_09950	COG1263	PTS System
OP863_09955	COG1609	Transcriptional regulator
OP863_09970	COG5339	Protein conserved in bacteria
OP863_09980	COG0114	fumarate hydratase activity
OP863_10000	COG2814	Major facilitator Superfamily
OP863_10005	COG0583	DNA-binding transcription factor activity
OP863_10010	COG1940	carbohydrate kinase activity
OP863_10015	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OP863_10040	COG1742	UPF0060 membrane protein
OP863_10045	COG4221	oxidoreductase activity
OP863_10060	COG1393	Belongs to the ArsC family
OP863_10065	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OP863_10070	COG0640	Transcriptional regulator
OP863_10095	COG0625	glutathione transferase activity
OP863_10100	COG3604	Transcriptional regulator
OP863_10105	COG0426	domain, Protein
OP863_10105	COG1773	rubredoxin
OP863_10110	COG0446	pyridine nucleotide-disulphide oxidoreductase
OP863_10120	COG1522	sequence-specific DNA binding
OP863_10150	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OP863_10170	COG3023	N-Acetylmuramoyl-L-alanine amidase
OP863_10185	COG0028	Belongs to the TPP enzyme family
OP863_10190	COG0440	acetolactate synthase activity
OP863_10195	COG1011	Hydrolase
OP863_10210	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_10220	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
OP863_10235	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OP863_10240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OP863_10245	COG0589	response to stress
OP863_10250	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
OP863_10255	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OP863_10265	COG0531	amino acid
OP863_10275	COG0745	RESPONSE REGULATOR receiver
OP863_10280	COG2205	protein histidine kinase activity
OP863_10285	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OP863_10305	COG3591	Belongs to the peptidase S1B family
OP863_10315	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
OP863_10320	COG1643	Atp-dependent helicase
OP863_10325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OP863_10330	COG3784	Protein of unknown function (DUF1318)
OP863_10340	COG2911	Protein conserved in bacteria
OP863_10345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OP863_10350	COG3042	response to heat
OP863_10355	COG1285	pathogenesis
OP863_10365	COG0674	pyruvate-flavodoxin oxidoreductase activity
OP863_10365	COG1013	pyruvate-flavodoxin oxidoreductase activity
OP863_10365	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OP863_10365	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OP863_10375	COG0037	tRNA processing
OP863_10380	COG0598	Magnesium transport protein CorA
OP863_10395	COG4166	transmembrane transport
OP863_10400	COG2866	Carboxypeptidase
OP863_10405	COG4948	Mandelate Racemase Muconate Lactonizing
OP863_10410	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
OP863_10420	COG5642	Protein of unknown function (DUF2384)
OP863_10425	COG5654	RES domain protein
OP863_10430	COG3768	UPF0283 membrane protein
OP863_10435	COG3106	COG3106 Predicted ATPase
OP863_10445	COG1983	PspC domain protein
OP863_10455	COG1842	Phage shock protein A
OP863_10460	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OP863_10475	COG4166	transmembrane transport
OP863_10480	COG4168	peptide transport system, permease
OP863_10485	COG4171	peptide transport system, permease
OP863_10495	COG4172	Belongs to the ABC transporter superfamily
OP863_10505	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OP863_10505	COG4950	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OP863_10515	COG3104	oligopeptide transport
OP863_10535	COG0625	glutathione transferase activity
OP863_10545	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OP863_10555	COG3895	Periplasmic Protein
OP863_10560	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OP863_10565	COG3133	Outer membrane lipoprotein
OP863_10570	COG1846	Transcriptional regulator
OP863_10580	COG1566	PFAM secretion protein HlyD family protein
OP863_10585	COG1289	transmembrane transporter activity
OP863_10590	COG4989	oxidoreductase activity
OP863_10595	COG3313	Fe-S protein
OP863_10600	COG2194	sulfuric ester hydrolase activity
OP863_10605	COG1309	transcriptional regulator
OP863_10610	COG1902	pentaerythritol trinitrate reductase activity
OP863_10615	COG0346	lactoylglutathione lyase activity
OP863_10620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OP863_10625	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OP863_10630	COG0791	NLP P60 protein
OP863_10645	COG1609	Transcriptional regulator
OP863_10650	COG0583	DNA-binding transcription factor activity
OP863_10655	COG2814	Major facilitator Superfamily
OP863_10660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OP863_10665	COG0307	riboflavin synthase, alpha
OP863_10670	COG0534	Mate efflux family protein
OP863_10700	COG1376	ErfK ybiS ycfS ynhG family protein
OP863_10700	COG1388	LysM domain
OP863_10705	COG2166	iron-sulfur cluster assembly
OP863_10715	COG0719	Fe-S assembly protein
OP863_10720	COG0396	ATPase activity
OP863_10725	COG0719	Fe-S assembly protein
OP863_10730	COG0316	Belongs to the HesB IscA family
OP863_10735	COG2050	protein possibly involved in aromatic compounds catabolism
OP863_10740	COG0277	FAD linked oxidase domain protein
OP863_10740	COG0247	lactate metabolic process
OP863_10745	COG0628	permease
OP863_10755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OP863_10755	COG0574	Belongs to the PEP-utilizing enzyme family
OP863_10760	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OP863_10780	COG3720	iron ion transport
OP863_10785	COG4558	Periplasmic binding protein
OP863_10795	COG0095	Lipoate-protein ligase
OP863_10800	COG0791	NLP P60 protein
OP863_10805	COG2076	Multidrug Resistance protein
OP863_10810	COG2076	Multidrug Resistance protein
OP863_10815	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OP863_10820	COG0726	polysaccharide deacetylase
OP863_10825	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OP863_10825	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP863_10830	COG0463	Glycosyl transferase, family 2
OP863_10835	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OP863_10840	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
OP863_10845	COG0386	Belongs to the glutathione peroxidase family
OP863_10850	COG4139	cobalamin transport
OP863_10860	COG3122	Protein conserved in bacteria
OP863_10865	COG0776	regulation of translation
OP863_10885	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OP863_10890	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OP863_10895	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OP863_10920	COG4249	Peptidase C14 caspase catalytic subunit p20
OP863_10925	COG1811	Na channel or pump
OP863_10960	COG0803	Belongs to the bacterial solute-binding protein 9 family
OP863_10965	COG1121	(ABC) transporter
OP863_10970	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OP863_10975	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OP863_10980	COG3001	Fructosamine kinase
OP863_10990	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OP863_10995	COG1917	Cupin 2, conserved barrel domain protein
OP863_11000	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
OP863_11005	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_11015	COG1175	transmembrane transport
OP863_11020	COG0395	ABC-type sugar transport system, permease component
OP863_11025	COG3842	ATPase activity
OP863_11030	COG1653	transport
OP863_11035	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OP863_11040	COG1988	membrane-bound metal-dependent
OP863_11045	COG1823	symporter activity
OP863_11050	COG3023	N-Acetylmuramoyl-L-alanine amidase
OP863_11060	COG0823	Involved in the tonB-independent uptake of proteins
OP863_11065	COG2814	Major facilitator Superfamily
OP863_11070	COG0501	Belongs to the peptidase M48B family
OP863_11075	COG0793	Belongs to the peptidase S41A family
OP863_11085	COG1956	GAF domain-containing protein
OP863_11090	COG2995	paraquat-inducible protein a
OP863_11095	COG3008	intermembrane lipid transfer
OP863_11105	COG2814	Major facilitator Superfamily
OP863_11145	COG2203	Gaf domain
OP863_11145	COG4251	negative regulation of phosphorylation
OP863_11145	COG5001	Diguanylate cyclase
OP863_11145	COG3706	GGDEF domain
OP863_11185	COG0668	transmembrane transport
OP863_11205	COG0786	glutamate:sodium symporter activity
OP863_11210	COG1187	pseudouridine synthase activity
OP863_11225	COG3077	Addiction module antitoxin, RelB DinJ family
OP863_11230	COG2026	Addiction module toxin, RelE StbE family
OP863_11250	COG0582	viral genome integration into host DNA
OP863_11270	COG3646	Phage regulatory protein
OP863_11375	COG3772	lysozyme
OP863_11470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OP863_11590	COG1276	copper resistance
OP863_11595	COG2372	response to copper ion
OP863_11600	COG1528	Iron-storage protein
OP863_11615	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OP863_11620	COG1770	oligopeptidase
OP863_11630	COG3097	Belongs to the UPF0267 family
OP863_11635	COG3141	response to X-ray
OP863_11640	COG0513	Belongs to the DEAD box helicase family
OP863_11645	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OP863_11650	COG3140	Belongs to the UPF0181 family
OP863_11660	COG0494	nUDIX hydrolase
OP863_11665	COG1760	l-serine dehydratase
OP863_11675	COG1253	flavin adenine dinucleotide binding
OP863_11680	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP863_11680	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP863_11685	COG3715	PTS system
OP863_11690	COG3716	PTS system mannose fructose sorbose family IID component
OP863_11695	COG4811	Protein of unknown function (DUF986)
OP863_11700	COG1971	Probably functions as a manganese efflux pump
OP863_11710	COG5002	protein histidine kinase activity
OP863_11710	COG5001	Diguanylate cyclase
OP863_11710	COG3447	MASE1 domain protein
OP863_11720	COG2226	methyltransferase
OP863_11725	COG0768	penicillin binding
OP863_11730	COG1496	oxidoreductase activity
OP863_11750	COG1113	amino acid transport
OP863_11785	COG2207	Transcriptional regulator
OP863_11810	COG1132	(ABC) transporter
OP863_11820	COG4251	negative regulation of phosphorylation
OP863_11820	COG5001	Diguanylate cyclase
OP863_11820	COG3706	GGDEF domain
OP863_11820	COG2203	Gaf domain
OP863_11830	COG3755	Protein conserved in bacteria
OP863_11855	COG1733	regulation of RNA biosynthetic process
OP863_11860	COG0702	epimerase
OP863_11865	COG2873	o-acetylhomoserine
OP863_11875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OP863_11880	COG0840	transmembrane signaling receptor activity
OP863_11905	COG0538	isocitrate dehydrogenase activity
OP863_11910	COG1187	pseudouridine synthase activity
OP863_11920	COG0482	sulfurtransferase activity
OP863_11925	COG2915	High frequency lysogenization protein hflD homolog
OP863_11930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OP863_11940	COG0745	RESPONSE REGULATOR receiver
OP863_11950	COG2850	peptidyl-arginine hydroxylation
OP863_11965	COG1940	carbohydrate kinase activity
OP863_11970	COG4591	ABC-type transport system involved in lipoprotein release permease component
OP863_11980	COG4591	ABC-type transport system involved in lipoprotein release permease component
OP863_11985	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OP863_11990	COG3134	Outer membrane lipoprotein
OP863_11995	COG1252	NADH dehydrogenase
OP863_12000	COG3150	esterase
OP863_12010	COG0510	thiamine kinase activity
OP863_12015	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
OP863_12020	COG5633	Lipoprotein
OP863_12025	COG0537	adenosine 5'-monophosphoramidase activity
OP863_12030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OP863_12045	COG0641	radical SAM
OP863_12065	COG1263	PTS System
OP863_12065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP863_12070	COG0084	hydrolase, TatD family'
OP863_12075	COG0470	DNA polymerase III
OP863_12080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OP863_12085	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OP863_12090	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OP863_12095	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OP863_12105	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_12110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
OP863_12120	COG0416	fatty acid biosynthetic process
OP863_12125	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OP863_12130	COG1399	metal-binding, possibly nucleic acid-binding protein
OP863_12140	COG0564	pseudouridine synthase activity
OP863_12145	COG1530	ribonuclease E activity
OP863_12145	COG1530	ribonuclease E activity
OP863_12150	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OP863_12155	COG0418	dihydroorotase activity
OP863_12185	COG0628	permease
OP863_12190	COG1054	Belongs to the UPF0176 family
OP863_12200	COG1560	Kdo2-lipid A biosynthetic process
OP863_12205	COG2259	Doxx family
OP863_12210	COG2814	Major facilitator Superfamily
OP863_12230	COG5645	(Lipo)protein
OP863_12235	COG2943	transferase activity, transferring hexosyl groups
OP863_12240	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
OP863_12255	COG3263	regulation of cellular component size
OP863_12270	COG4235	cytochrome complex assembly
OP863_12275	COG3088	subunit of a heme lyase
OP863_12275	COG4235	cytochrome complex assembly
OP863_12280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP863_12285	COG1138	Cytochrome C-type biogenesis protein
OP863_12290	COG3301	Polysulphide reductase, NrfD
OP863_12295	COG0437	4 iron, 4 sulfur cluster binding
OP863_12300	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
OP863_12315	COG2920	part of a sulfur-relay system
OP863_12320	COG1254	Belongs to the acylphosphatase family
OP863_12330	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OP863_12335	COG3785	DNA binding
OP863_12340	COG1832	CoA-binding protein
OP863_12355	COG0210	DNA helicase
OP863_12360	COG3304	Inner membrane component domain
OP863_12365	COG1289	transmembrane transporter activity
OP863_12370	COG3070	regulator of competence-specific genes
OP863_12375	COG5404	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division
OP863_12385	COG3120	sequence-specific DNA binding
OP863_12390	COG1067	ATP-dependent peptidase activity
OP863_12395	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OP863_12405	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OP863_12415	COG3130	regulation of translation
OP863_12420	COG3009	Protein conserved in bacteria
OP863_12425	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OP863_12425	COG3008	intermembrane lipid transfer
OP863_12430	COG2995	paraquat-inducible protein a
OP863_12435	COG0488	(ABC) transporter
OP863_12440	COG0116	Belongs to the methyltransferase superfamily
OP863_12440	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OP863_12445	COG3217	Mosc domain protein beta barrel domain protein
OP863_12445	COG0633	Ferredoxin
OP863_12455	COG0167	dihydroorotate dehydrogenase activity
OP863_12460	COG0308	aminopeptidase N
OP863_12465	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
OP863_12470	COG0017	Asparaginyl-tRNA synthetase
OP863_12480	COG1448	Aminotransferase
OP863_12485	COG2200	EAL domain
OP863_12490	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OP863_12495	COG3108	Peptidase M15
OP863_12500	COG2989	Protein conserved in bacteria
OP863_12505	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OP863_12515	COG3006	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity
OP863_12520	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OP863_12525	COG1434	Gram-negative-bacterium-type cell wall biogenesis
OP863_12530	COG3173	Aminoglycoside phosphotransferase
OP863_12535	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OP863_12540	COG2835	tetraacyldisaccharide 4'-kinase activity
OP863_12545	COG1278	Cold shock
OP863_12550	COG5383	Protein conserved in bacteria
OP863_12555	COG1663	tetraacyldisaccharide 4'-kinase activity
OP863_12565	COG0658	competence protein
OP863_12565	COG2333	competence protein COMEC
OP863_12575	COG0539	negative regulation of cytoplasmic translation
OP863_12580	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OP863_12585	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OP863_12595	COG2323	membrane
OP863_12600	COG0252	asparaginase activity
OP863_12605	COG1944	ATP diphosphatase activity
OP863_12610	COG2116	formate transmembrane transporter activity
OP863_12615	COG1882	Formate acetyltransferase
OP863_12620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OP863_12625	COG2814	Major facilitator Superfamily
OP863_12630	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OP863_12635	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OP863_12640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OP863_12645	COG1674	ftsk spoiiie
OP863_12645	COG3107	peptidoglycan biosynthetic process
OP863_12655	COG0492	ferredoxin-NADP+ reductase activity
OP863_12665	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OP863_12670	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OP863_12675	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OP863_12680	COG0542	response to heat
OP863_12685	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OP863_12690	COG1278	Cold shock
OP863_12700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP863_12705	COG2990	Protein conserved in bacteria
OP863_12710	COG3593	DNA synthesis involved in DNA repair
OP863_12715	COG2431	L-lysine efflux transmembrane transporter activity
OP863_12720	COG1151	hydroxylamine reductase activity
OP863_12725	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OP863_12730	COG0028	Belongs to the TPP enzyme family
OP863_12740	COG2008	Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde
OP863_12745	COG0702	epimerase
OP863_12750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP863_12760	COG1126	abc transporter atp-binding protein
OP863_12765	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP863_12770	COG4215	(ABC) transporter
OP863_12775	COG4160	amino acid transport
OP863_12780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP863_12785	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OP863_12795	COG1177	transmembrane transport
OP863_12800	COG1176	ABC-type spermidine putrescine transport system, permease component I
OP863_12805	COG3842	ATPase activity
OP863_12810	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OP863_12830	COG2985	domain, Protein
OP863_12830	COG0569	domain protein
OP863_12840	COG0671	phosphoesterase, PA-phosphatase related
OP863_12845	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OP863_12850	COG1349	DNA-binding transcription factor activity
OP863_12855	COG0814	amino acid
OP863_12860	COG1760	l-serine dehydratase
OP863_12865	COG1686	Belongs to the peptidase S11 family
OP863_12875	COG0626	cystathionine gamma-synthase activity
OP863_12890	COG2011	ABC-type metal ion transport system permease component
OP863_12915	COG0625	glutathione transferase activity
OP863_12920	COG4771	TonB-dependent receptor
OP863_12930	COG0833	amino acid
OP863_12935	COG0583	DNA-binding transcription factor activity
OP863_12945	COG2855	membrane
OP863_12950	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OP863_12955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OP863_12955	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OP863_12955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OP863_12960	COG1105	Belongs to the carbohydrate kinase PfkB family
OP863_12990	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OP863_13000	COG0246	Mannitol dehydrogenase
OP863_13005	COG2186	Transcriptional regulator
OP863_13015	COG0523	cobalamin synthesis protein
OP863_13025	COG0791	NLP P60 protein
OP863_13030	COG2200	EAL domain
OP863_13035	COG4166	transmembrane transport
OP863_13040	COG4174	ABC transporter (Permease)
OP863_13045	COG4239	(ABC) transporter, permease
OP863_13050	COG4172	Belongs to the ABC transporter superfamily
OP863_13060	COG2814	Major facilitator Superfamily
OP863_13065	COG1187	pseudouridine synthase activity
OP863_13070	COG1061	Type III restriction enzyme res subunit
OP863_13080	COG3081	Nucleoid-associated protein
OP863_13085	COG3082	Protein of unknown function (DUF1414)
OP863_13100	COG2723	6-phospho-beta-galactosidase activity
OP863_13105	COG2190	(PTS) system
OP863_13105	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP863_13105	COG1263	PTS System
OP863_13155	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
OP863_13170	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
OP863_13180	COG1132	(ABC) transporter
OP863_13195	COG2223	nitrite transmembrane transporter activity
OP863_13200	COG0642	Histidine kinase
OP863_13200	COG2198	Histidine kinase
OP863_13210	COG0784	Response regulator, receiver
OP863_13210	COG2205	protein histidine kinase activity
OP863_13220	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OP863_13225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OP863_13235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OP863_13240	COG4574	serine-type endopeptidase inhibitor activity
OP863_13250	COG0814	amino acid
OP863_13270	COG1441	menaquinone biosynthetic process
OP863_13275	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OP863_13280	COG0596	Alpha beta hydrolase
OP863_13285	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OP863_13290	COG1169	isochorismate synthase
OP863_13300	COG4575	ribosome binding
OP863_13305	COG0129	dihydroxy-acid dehydratase activity
OP863_13310	COG4702	Belongs to the UPF0303 family
OP863_13320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OP863_13325	COG1609	Transcriptional regulator
OP863_13330	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_13335	COG3265	gluconokinase activity
OP863_13340	COG2731	YhcH YjgK YiaL family protein
OP863_13355	COG1007	ATP synthesis coupled electron transport
OP863_13360	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OP863_13365	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
OP863_13370	COG0713	ATP synthesis coupled electron transport
OP863_13375	COG0839	Belongs to the complex I subunit 6 family
OP863_13380	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OP863_13390	COG1034	ATP synthesis coupled electron transport
OP863_13405	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OP863_13405	COG0649	NAD binding
OP863_13410	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OP863_13420	COG0583	DNA-binding transcription factor activity
OP863_13425	COG0436	Aminotransferase
OP863_13430	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
OP863_13435	COG0490	domain, Protein
OP863_13435	COG0471	metal ion transport
OP863_13445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OP863_13450	COG3013	Belongs to the UPF0304 family
OP863_13455	COG3092	negative regulation of chromosome organization
OP863_13465	COG0280	phosphate acetyltransferase
OP863_13465	COG0857	belongs to the CobB CobQ family
OP863_13470	COG1609	Transcriptional regulator
OP863_13475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP863_13485	COG3037	sugar-specific permease SgaT UlaA
OP863_13490	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
OP863_13495	COG0622	Phosphoesterase
OP863_13505	COG1090	epimerase
OP863_13510	COG4598	ABC transporter
OP863_13515	COG4160	amino acid transport
OP863_13520	COG4215	(ABC) transporter
OP863_13525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP863_13535	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OP863_13540	COG1286	toxin biosynthetic process
OP863_13545	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
OP863_13550	COG0285	dihydrofolate synthase activity
OP863_13560	COG0586	Pfam SNARE associated Golgi protein
OP863_13570	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OP863_13575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OP863_13580	COG2207	Transcriptional regulator
OP863_13585	COG0697	spore germination
OP863_13595	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OP863_13600	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP863_13610	COG4232	protein-disulfide reductase activity
OP863_13625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
OP863_13635	COG1609	Transcriptional regulator
OP863_13645	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OP863_13650	COG2723	6-phospho-beta-galactosidase activity
OP863_13655	COG1447	Phosphotransferase system cellobiose-specific component IIA
OP863_13665	COG1794	racemase activity, acting on amino acids and derivatives
OP863_13670	COG3706	GGDEF domain
OP863_13675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OP863_13680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OP863_13680	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OP863_13690	COG3101	peptidyl-lysine hydroxylation
OP863_13695	COG0730	response to heat
OP863_13700	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
OP863_13705	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OP863_13710	COG2890	protein-(glutamine-N5) methyltransferase activity
OP863_13715	COG2840	Smr protein MutS2
OP863_13720	COG2062	phosphohistidine phosphatase, SixA
OP863_13725	COG1024	Enoyl-CoA hydratase
OP863_13725	COG1250	3-hydroxyacyl-CoA dehydrogenase
OP863_13730	COG0183	Belongs to the thiolase family
OP863_13735	COG3691	Protein conserved in bacteria
OP863_13740	COG2067	long-chain fatty acid transport protein
OP863_13750	COG3088	subunit of a heme lyase
OP863_13750	COG4235	cytochrome complex assembly
OP863_13755	COG4235	cytochrome complex assembly
OP863_13755	COG3088	subunit of a heme lyase
OP863_13760	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OP863_13765	COG1138	Cytochrome C-type biogenesis protein
OP863_13770	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OP863_13775	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OP863_13780	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OP863_13785	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OP863_13795	COG2116	formate transmembrane transporter activity
OP863_13940	COG2205	protein histidine kinase activity
OP863_13945	COG0745	RESPONSE REGULATOR receiver
OP863_13950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP863_13955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OP863_13960	COG3708	Transcriptional regulator
OP863_13960	COG2207	Transcriptional regulator
OP863_13970	COG0582	viral genome integration into host DNA
OP863_13980	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OP863_13985	COG2501	S4 domain
OP863_13990	COG0215	cysteine-tRNA ligase activity
OP863_13995	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OP863_14000	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OP863_14005	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OP863_14010	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OP863_14015	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OP863_14020	COG4181	ATPase activity
OP863_14025	COG2755	lipolytic protein G-D-S-L family
OP863_14030	COG0300	oxidoreductase activity
OP863_14035	COG3118	belongs to the thioredoxin family
OP863_14040	COG0330	HflC and HflK could
OP863_14045	COG1585	Membrane protein implicated in regulation of membrane protease activity
OP863_14050	COG0789	Transcriptional regulator
OP863_14055	COG2217	Heavy metal translocating P-type atpase
OP863_14060	COG3735	TraB family
OP863_14065	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OP863_14075	COG0737	Belongs to the 5'-nucleotidase family
OP863_14085	COG2223	nitrite transmembrane transporter activity
OP863_14090	COG4651	solute:proton antiporter activity
OP863_14090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OP863_14095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OP863_14115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OP863_14120	COG0438	transferase activity, transferring glycosyl groups
OP863_14125	COG0438	transferase activity, transferring glycosyl groups
OP863_14130	COG1215	transferase activity, transferring glycosyl groups
OP863_14135	COG1216	Glycosyl transferase, family 2
OP863_14135	COG1442	glycosyl transferase family 8
OP863_14140	COG2244	polysaccharide biosynthetic process
OP863_14145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OP863_14150	COG0563	adenylate kinase activity
OP863_14155	COG0326	Molecular chaperone. Has ATPase activity
OP863_14160	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OP863_14165	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OP863_14170	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
OP863_14175	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OP863_14180	COG2832	Protein of unknown function (DUF454)
OP863_14195	COG1196	nuclear chromosome segregation
OP863_14195	COG3264	Mechanosensitive ion channel
OP863_14200	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OP863_14205	COG1309	transcriptional regulator
OP863_14210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP863_14215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OP863_14225	COG3457	Alanine racemase
OP863_14230	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OP863_14245	COG0254	rRNA binding
OP863_14250	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OP863_14255	COG0803	Belongs to the bacterial solute-binding protein 9 family
OP863_14260	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OP863_14265	COG1121	(ABC) transporter
OP863_14290	COG3695	enzyme binding
OP863_14295	COG3126	Type III secretion system lipoprotein chaperone (YscW)
OP863_14300	COG1946	Acyl-CoA thioesterase
OP863_14305	COG0004	ammonium transporteR
OP863_14310	COG0347	Belongs to the P(II) protein family
OP863_14320	COG1132	(ABC) transporter
OP863_14325	COG1132	(ABC) transporter
OP863_14330	COG1522	sequence-specific DNA binding
OP863_14340	COG0561	phosphatase activity
OP863_14345	COG4533	DNA binding
OP863_14350	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OP863_14355	COG0824	Thioesterase
OP863_14360	COG1555	photosystem II stabilization
OP863_14365	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OP863_14370	COG0776	regulation of translation
OP863_14375	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OP863_14380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OP863_14390	COG0544	peptidyl-prolyl cis-trans isomerase activity
OP863_14395	COG0271	Belongs to the BolA IbaG family
OP863_14400	COG3056	Lipoprotein
OP863_14405	COG2223	nitrite transmembrane transporter activity
OP863_14415	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OP863_14420	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OP863_14425	COG1845	cytochrome c oxidase, subunit III
OP863_14430	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OP863_14435	COG0109	protoheme IX farnesyltransferase activity
OP863_14440	COG2814	Major facilitator Superfamily
OP863_14445	COG1666	GTP binding
OP863_14450	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
OP863_14460	COG0301	tRNA thio-modification
OP863_14460	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OP863_14465	COG1722	exodeoxyribonuclease VII activity
OP863_14470	COG0142	geranyltranstransferase activity
OP863_14475	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OP863_14480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OP863_14485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OP863_14490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OP863_14495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OP863_14500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OP863_14500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OP863_14515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OP863_14520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OP863_14525	COG1862	Preprotein translocase
OP863_14530	COG0343	queuine tRNA-ribosyltransferase activity
OP863_14545	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
OP863_14550	COG0450	alkyl hydroperoxide reductase
OP863_14565	COG0366	Alpha amylase catalytic
OP863_14585	COG5002	protein histidine kinase activity
OP863_14590	COG0745	RESPONSE REGULATOR receiver
OP863_14595	COG0420	3'-5' exonuclease activity
OP863_14600	COG0419	ATPase involved in DNA repair
OP863_14605	COG1940	carbohydrate kinase activity
OP863_14610	COG2974	May be involved in recombination
OP863_14615	COG3123	guanosine phosphorylase activity
OP863_14620	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OP863_14655	COG2226	methyltransferase
OP863_14670	COG3459	Glycosyltransferase 36 associated
OP863_14690	COG2188	Transcriptional regulator
OP863_14695	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OP863_14700	COG2313	pseudouridylate synthase activity
OP863_14705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OP863_14710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OP863_14715	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
OP863_14725	COG1073	alpha beta
OP863_14730	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
OP863_14735	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OP863_14750	COG0438	transferase activity, transferring glycosyl groups
OP863_14775	COG1086	Polysaccharide biosynthesis protein
OP863_14795	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
OP863_14800	COG2195	Cleaves the N-terminal amino acid of tripeptides
OP863_14805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OP863_14820	COG2964	Protein conserved in bacteria
OP863_14835	COG2991	Protein conserved in bacteria
OP863_14840	COG1477	protein flavinylation
OP863_14845	COG2871	sodium ion transport
OP863_14850	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OP863_14855	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OP863_14860	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OP863_14865	COG1805	sodium ion transport
OP863_14870	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OP863_14875	COG3034	peptidoglycan biosynthetic process
OP863_14880	COG0121	glutamine amidotransferase
OP863_14885	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OP863_14890	COG1960	acyl-CoA dehydrogenase activity
OP863_14895	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
OP863_14900	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
OP863_14905	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OP863_14910	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
OP863_14915	COG0235	Class ii aldolase
OP863_14920	COG0436	Aminotransferase
OP863_14930	COG2814	Major facilitator Superfamily
OP863_14935	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
OP863_14945	COG1846	Transcriptional regulator
OP863_14955	COG1566	PFAM secretion protein HlyD family protein
OP863_14960	COG2814	Major facilitator Superfamily
OP863_14965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OP863_14970	COG3118	belongs to the thioredoxin family
OP863_14975	COG3148	PFAM DTW domain containing protein
OP863_14980	COG1042	CoA-binding domain protein
OP863_14980	COG0045	succinate-CoA ligase (ADP-forming) activity
OP863_14980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OP863_14985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OP863_14990	COG5544	Lipoprotein
OP863_15020	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OP863_15030	COG2011	ABC-type metal ion transport system permease component
OP863_15035	COG1464	Belongs to the NlpA lipoprotein family
OP863_15045	COG1720	tRNA m6t6A37 methyltransferase activity
OP863_15050	COG0442	prolyl-tRNA aminoacylation
OP863_15055	COG3015	lipoprotein NlpE involved in copper resistance
OP863_15065	COG4681	YaeQ
OP863_15075	COG4568	rho-dependent transcription termination
OP863_15090	COG0346	lactoylglutathione lyase activity
OP863_15105	COG0825	malonyl-CoA metabolic process
OP863_15110	COG0587	DNA-directed DNA polymerase activity
OP863_15115	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OP863_15125	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OP863_15130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OP863_15135	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OP863_15140	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
OP863_15150	COG0750	zinc metalloprotease
OP863_15155	COG0575	Belongs to the CDS family
OP863_15165	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OP863_15170	COG0233	cytoplasmic translational termination
OP863_15175	COG0528	UMP kinase activity
OP863_15180	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OP863_15185	COG0052	Belongs to the universal ribosomal protein uS2 family
OP863_15195	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OP863_15200	COG2171	N-acyltransferase activity
OP863_15215	COG0564	pseudouridine synthase activity
OP863_15220	COG3098	single-species biofilm formation
OP863_15230	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OP863_15230	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OP863_15235	COG1611	Belongs to the LOG family
OP863_15240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OP863_15245	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OP863_15250	COG2363	Small membrane protein
OP863_15255	COG0583	DNA-binding transcription factor activity
OP863_15265	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OP863_15270	COG2166	iron-sulfur cluster assembly
OP863_15275	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OP863_15280	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
OP863_15300	COG0860	N-Acetylmuramoyl-L-alanine amidase
OP863_15305	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OP863_15305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OP863_15310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OP863_15315	COG1074	ATP-dependent DNA helicase activity
OP863_15320	COG1025	Belongs to the peptidase M16 family
OP863_15325	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OP863_15330	COG4967	type IV pilus modification protein PilV
OP863_15350	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OP863_15355	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OP863_15365	COG1051	belongs to the nudix hydrolase family
OP863_15370	COG3066	DNA modification
OP863_15375	COG0861	Integral membrane protein TerC family
OP863_15380	COG0667	Aldo Keto reductase
OP863_15385	COG0477	Major facilitator Superfamily
OP863_15390	COG0204	Acyl-transferase
OP863_15390	COG0318	PFAM AMP-dependent synthetase and ligase
OP863_15400	COG1609	Transcriptional regulator
OP863_15410	COG0583	DNA-binding transcription factor activity
OP863_15415	COG2814	Major facilitator Superfamily
OP863_15420	COG0583	DNA-binding transcription factor activity
OP863_15460	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OP863_15490	COG2165	general secretion pathway protein
OP863_15500	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OP863_15520	COG0288	reversible hydration of carbon dioxide
OP863_15525	COG1733	regulation of RNA biosynthetic process
OP863_15530	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_15540	COG0484	heat shock protein binding
OP863_15545	COG1609	Transcriptional regulator
OP863_15550	COG2271	Major facilitator Superfamily
OP863_15565	COG1522	sequence-specific DNA binding
OP863_15695	COG0582	viral genome integration into host DNA
OP863_15705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OP863_15715	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OP863_15720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OP863_15725	COG4974	Belongs to the 'phage' integrase family
OP863_15730	COG0716	FMN binding
OP863_15735	COG4452	Inner membrane protein CreD
OP863_15740	COG2205	protein histidine kinase activity
OP863_15745	COG0745	RESPONSE REGULATOR receiver
OP863_15760	COG0354	folic acid binding
OP863_15765	COG1272	protein, Hemolysin III
OP863_15775	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_15780	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OP863_15780	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OP863_15785	COG0509	glycine decarboxylation via glycine cleavage system
OP863_15790	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OP863_15795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OP863_15800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OP863_15805	COG0006	proline dipeptidase activity
OP863_15810	COG3079	Belongs to the UPF0149 family
OP863_15815	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
OP863_15825	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OP863_15830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OP863_15835	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OP863_15840	COG0583	DNA-binding transcription factor activity
OP863_15850	COG1279	arginine transmembrane transporter activity
OP863_15860	COG0191	fructose-bisphosphate aldolase activity
OP863_15865	COG0126	phosphoglycerate kinase activity
OP863_15870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OP863_15875	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OP863_15880	COG0501	Belongs to the peptidase M48B family
OP863_15890	COG1166	arginine decarboxylase activity
OP863_15895	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
OP863_15910	COG0640	Transcriptional regulator
OP863_15915	COG3091	SprT-like family
OP863_15920	COG2356	endonuclease I
OP863_15925	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OP863_15930	COG0189	ligase activity
OP863_15935	COG1678	Uncharacterized ACR, COG1678
OP863_15940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OP863_15945	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OP863_15955	COG2805	Type II/IV secretion system protein
OP863_15960	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OP863_15965	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OP863_15970	COG0762	integral membrane protein
OP863_15975	COG1872	DUF167
OP863_15980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OP863_15985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OP863_16000	COG3171	Protein conserved in bacteria
OP863_16005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OP863_16010	COG1194	a g-specific adenine glycosylase
OP863_16015	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
OP863_16020	COG0741	lytic transglycosylase activity
OP863_16030	COG1982	Orn Lys Arg decarboxylase major
OP863_16040	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OP863_16110	COG3657	addiction module killer protein
OP863_16155	COG0497	DNA recombination
OP863_16335	COG2211	Major facilitator Superfamily
OP863_16380	COG2197	response regulator
OP863_16385	COG0784	Response regulator, receiver
OP863_16385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP863_16385	COG2198	Histidine kinase
OP863_16385	COG2205	protein histidine kinase activity
OP863_16390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OP863_16400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OP863_16405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OP863_16545	COG3179	chitinase
OP863_16565	COG2885	chlorophyll binding
OP863_16600	COG1289	transmembrane transporter activity
OP863_16630	COG4604	ABC transporter, ATP-binding protein
OP863_16635	COG4605	iron ion homeostasis
OP863_16645	COG4607	ABC-type enterochelin transport system periplasmic component
OP863_16660	COG0477	Major facilitator Superfamily
OP863_16665	COG1609	Transcriptional regulator
OP863_16675	COG1283	sodium-dependent phosphate transmembrane transporter activity
OP863_16680	COG2195	Cleaves the N-terminal amino acid of tripeptides
OP863_16685	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OP863_16725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP863_16730	COG5001	Diguanylate cyclase
OP863_16740	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
OP863_16745	COG0309	Hydrogenase expression formation protein (HypE)
OP863_16750	COG0409	Hydrogenase expression formation protein
OP863_16755	COG0298	carbon dioxide binding
OP863_16760	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
OP863_16770	COG1773	rubredoxin
OP863_16775	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OP863_16780	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
OP863_16785	COG5557	Pfam Polysulphide reductase, NrfD
OP863_16790	COG0437	4 iron, 4 sulfur cluster binding
OP863_16795	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
OP863_16800	COG3133	Outer membrane lipoprotein
OP863_16820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP863_16825	COG2271	Major facilitator Superfamily
OP863_16830	COG1028	Short-chain dehydrogenase reductase Sdr
OP863_16835	COG3433	isochorismatase activity
OP863_16835	COG1535	isochorismatase
OP863_16840	COG1021	2,3-dihydroxybenzoate-AMP ligase
OP863_16845	COG1169	isochorismate synthase
OP863_16850	COG4592	Periplasmic binding protein
OP863_16855	COG1120	ATPase activity
OP863_16860	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP863_16865	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OP863_16875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OP863_16890	COG4774	siderophore transport
OP863_16910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OP863_16915	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OP863_16945	COG4964	Belongs to the GSP D family
OP863_16990	COG0848	biopolymer transport protein
OP863_17005	COG0586	Pfam SNARE associated Golgi protein
OP863_17010	COG2207	Transcriptional regulator
OP863_17015	COG1979	alcohol dehydrogenase
OP863_17020	COG0656	L-ascorbic acid biosynthetic process
OP863_17030	COG2132	Multicopper oxidase
OP863_17045	COG2249	NAD(P)H dehydrogenase (quinone) activity
OP863_17050	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
OP863_17055	COG0583	DNA-binding transcription factor activity
OP863_17065	COG3150	esterase
OP863_17070	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
OP863_17075	COG3151	Protein conserved in bacteria
OP863_17080	COG0494	nUDIX hydrolase
OP863_17085	COG1538	Outer membrane efflux protein
OP863_17090	COG5463	Belongs to the UPF0441 family
OP863_17095	COG0754	glutathionylspermidine amidase activity
OP863_17100	COG3384	dioxygenase
OP863_17105	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OP863_17115	COG0531	amino acid
OP863_17120	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OP863_17120	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OP863_17125	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OP863_17130	COG3025	triphosphatase activity
OP863_17135	COG4991	sh3 domain protein
OP863_17140	COG0617	tRNA 3'-terminal CCA addition
OP863_17145	COG1968	undecaprenyl-diphosphatase activity
OP863_17150	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OP863_17155	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OP863_17160	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OP863_17165	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OP863_17170	COG0358	DNA primase activity
OP863_17185	COG3876	Protein conserved in bacteria
OP863_17195	COG1472	Belongs to the glycosyl hydrolase 3 family
OP863_17205	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OP863_17210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP863_17210	COG1263	PTS System
OP863_17220	COG0531	amino acid
OP863_17225	COG0076	glutamate decarboxylase activity
OP863_17235	COG3247	response to pH
OP863_17245	COG1902	pentaerythritol trinitrate reductase activity
OP863_17245	COG0446	pyridine nucleotide-disulphide oxidoreductase
OP863_17250	COG2813	Specifically methylates the guanine in position
OP863_17260	COG1451	nucleotide metabolic process
OP863_17265	COG0673	inositol 2-dehydrogenase activity
OP863_17270	COG0861	Integral membrane protein TerC family
OP863_17275	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OP863_17285	COG2721	sulfolactate sulfo-lyase activity
OP863_17290	COG0246	Mannitol dehydrogenase
OP863_17295	COG1904	glucuronate isomerase
OP863_17300	COG2271	Major facilitator Superfamily
OP863_17315	COG0586	Pfam SNARE associated Golgi protein
OP863_17330	COG4575	ribosome binding
OP863_17335	COG5393	Putative Actinobacterial Holin-X, holin superfamily III
OP863_17345	COG2259	Doxx family
OP863_17350	COG0435	Glutathione S-transferase
OP863_17355	COG0583	DNA-binding transcription factor activity
OP863_17360	COG1741	Belongs to the pirin family
OP863_17365	COG1064	alcohol dehydrogenase
OP863_17370	COG4221	oxidoreductase activity
OP863_17380	COG0667	Aldo Keto reductase
OP863_17415	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OP863_17425	COG0792	nuclease activity
OP863_17430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OP863_17435	COG2823	Periplasmic or secreted lipoprotein
OP863_17440	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OP863_17445	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
OP863_17450	COG5002	protein histidine kinase activity
OP863_17450	COG2198	Histidine kinase
OP863_17450	COG0784	Response regulator, receiver
OP863_17455	COG1242	4 iron, 4 sulfur cluster binding
OP863_17460	COG0070	glutamate synthase
OP863_17460	COG0069	glutamate synthase activity
OP863_17460	COG0067	glutamate synthase
OP863_17465	COG0493	'glutamate synthase
OP863_17475	COG2969	positive regulation of protein catabolic process
OP863_17480	COG0625	glutathione transferase activity
OP863_17485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OP863_17490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OP863_17495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OP863_17500	COG3105	Protein conserved in bacteria
OP863_17505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OP863_17510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OP863_17515	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OP863_17520	COG5007	Belongs to the BolA IbaG family
OP863_17525	COG3113	response to antibiotic
OP863_17530	COG2854	intermembrane phospholipid transfer
OP863_17535	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OP863_17540	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OP863_17545	COG1127	ABC transporter
OP863_17550	COG0530	calcium, potassium:sodium antiporter activity
OP863_17555	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OP863_17555	COG0517	IMP dehydrogenase activity
OP863_17560	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OP863_17565	COG3117	lipopolysaccharide transmembrane transporter activity
OP863_17570	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OP863_17575	COG1137	ATPase activity
OP863_17580	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OP863_17595	COG1660	Displays ATPase and GTPase activities
OP863_17600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP863_17605	COG0540	Belongs to the ATCase OTCase family
OP863_17610	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
OP863_17620	COG0366	Alpha amylase catalytic
OP863_17625	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OP863_17625	COG1263	PTS System
OP863_17635	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
OP863_17640	COG3711	transcriptional antiterminator
OP863_17640	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OP863_17645	COG2706	6-phosphogluconolactonase activity
OP863_17660	COG3964	amidohydrolase
OP863_17690	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OP863_17695	COG3783	Cytochrome b(562)
OP863_17700	COG0312	modulator of DNA gyrase
OP863_17705	COG3028	Belongs to the UPF0307 family
OP863_17710	COG2732	(Barnase) inhibitor
OP863_17725	COG1289	transmembrane transporter activity
OP863_17730	COG1566	PFAM secretion protein HlyD family protein
OP863_17740	COG0583	DNA-binding transcription factor activity
OP863_17780	COG0312	modulator of DNA gyrase
OP863_17785	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OP863_17790	COG3164	Protein of unknown function
OP863_17795	COG1530	ribonuclease E activity
OP863_17800	COG0424	maF-like protein
OP863_17805	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OP863_17810	COG1792	Involved in formation and maintenance of cell shape
OP863_17815	COG1077	Cell shape determining protein MreB Mrl
OP863_17820	COG2200	EAL domain
OP863_17820	COG2199	diguanylate cyclase activity
OP863_17825	COG0604	alcohol dehydrogenase
OP863_17835	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
OP863_17840	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OP863_17845	COG0511	ligase activity, forming carbon-carbon bonds
OP863_17850	COG0439	Biotin carboxylase
OP863_17855	COG3924	membrane
OP863_17860	COG4145	pantothenate transmembrane transporter activity
OP863_17865	COG2264	protein methyltransferase activity
OP863_17870	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OP863_17875	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OP863_17880	COG3706	GGDEF domain
OP863_17885	COG3133	Outer membrane lipoprotein
OP863_17890	COG1278	Cold shock
OP863_17895	COG1278	Cold shock
OP863_17900	COG1278	Cold shock
OP863_17905	COG0471	metal ion transport
OP863_17910	COG1560	Kdo2-lipid A biosynthetic process
OP863_17925	COG1380	Effector of murein hydrolase LrgA
OP863_17930	COG0583	DNA-binding transcription factor activity
OP863_17935	COG0025	NhaP-type Na H and K H
OP863_17940	COG2252	PERMEase
OP863_17965	COG0629	single-stranded DNA binding
OP863_17970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OP863_17975	COG2315	Protein conserved in bacteria
OP863_17980	COG1448	Aminotransferase
OP863_18010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OP863_18015	COG0735	belongs to the Fur family
OP863_18020	COG3237	CsbD-like
OP863_18025	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OP863_18030	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OP863_18035	COG2937	Belongs to the GPAT DAPAT family
OP863_18040	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OP863_18045	COG3161	chorismate lyase activity
OP863_18070	COG2182	Extracellular solute-binding protein
OP863_18075	COG1175	transmembrane transport
OP863_18080	COG3833	ABC-type maltose transport systems, permease component
OP863_18085	COG3223	Belongs to the PsiE family
OP863_18095	COG0527	aspartate kinase activity
OP863_18120	COG1414	Transcriptional regulator
OP863_18125	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OP863_18130	COG2224	Isocitrate lyase
OP863_18135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OP863_18140	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OP863_18185	COG0138	bifunctional purine biosynthesis protein purh
OP863_18190	COG0151	Belongs to the GarS family
OP863_18210	COG1515	deoxyribonuclease V activity
OP863_18215	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OP863_18220	COG2816	NAD+ diphosphatase activity
OP863_18225	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
OP863_18240	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OP863_18245	COG2104	thiamine diphosphate biosynthetic process
OP863_18250	COG2022	thiamine diphosphate biosynthetic process
OP863_18255	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OP863_18265	COG0085	RNA polymerase activity
OP863_18275	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OP863_18280	COG0081	regulation of translation
OP863_18285	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OP863_18290	COG0250	Participates in transcription elongation, termination and antitermination
OP863_18300	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OP863_18330	COG1072	(Pantothenic acid kinase))
OP863_18370	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OP863_18375	COG1739	Uncharacterized protein family UPF0029
OP863_18380	COG0006	proline dipeptidase activity
OP863_18385	COG1250	3-hydroxyacyl-CoA dehydrogenase
OP863_18385	COG1024	Enoyl-CoA hydratase
OP863_18390	COG0183	Belongs to the thiolase family
OP863_18400	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OP863_18420	COG0805	protein transport
OP863_18425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OP863_18430	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OP863_18435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OP863_18445	COG2226	methyltransferase
OP863_18450	COG1322	Protein conserved in bacteria
OP863_18455	COG0586	Pfam SNARE associated Golgi protein
OP863_18460	COG1966	Carbon starvation protein
OP863_18475	COG0412	Dienelactone hydrolase
OP863_18480	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OP863_18485	COG0583	DNA-binding transcription factor activity
OP863_18490	COG0697	spore germination
OP863_18495	COG0679	Auxin Efflux Carrier
OP863_18500	COG0584	glycerophosphoryl diester phosphodiesterase
OP863_18505	COG3842	ATPase activity
OP863_18510	COG0395	ABC-type sugar transport system, permease component
OP863_18515	COG1175	transmembrane transport
OP863_18520	COG1653	transport
OP863_18555	COG0410	ABC transporter
OP863_18565	COG4177	L-phenylalanine transmembrane transporter activity
OP863_18575	COG0683	leucine binding
OP863_18590	COG2177	Part of the ABC transporter FtsEX involved in
OP863_18595	COG2884	Cell division ATP-binding protein ftsE
OP863_18600	COG0552	protein localization to endoplasmic reticulum
OP863_18605	COG0742	ribosomal rna small subunit methyltransferase
OP863_18610	COG3776	membrane
OP863_18625	COG3714	YhhN family
OP863_18635	COG0425	Belongs to the sulfur carrier protein TusA family
OP863_18640	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OP863_18650	COG0247	lactate metabolic process
OP863_18660	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OP863_18670	COG2271	Major facilitator Superfamily
OP863_18675	COG0584	glycerophosphoryl diester phosphodiesterase
OP863_18680	COG0561	phosphatase activity
OP863_18685	COG2267	carboxylic ester hydrolase activity
OP863_18690	COG1280	lysine exporter protein (LysE YggA)
OP863_18695	COG1280	lysine exporter protein (LysE YggA)
OP863_18700	COG0514	ATP-dependent DNA helicase (RecQ)
OP863_18705	COG2829	1-acyl-2-lysophosphatidylserine acylhydrolase activity
OP863_18710	COG2050	protein possibly involved in aromatic compounds catabolism
OP863_18730	COG5564	TIM-barrel signal transduction protein
OP863_18735	COG5441	Belongs to the UPF0261 family
OP863_18745	COG0210	DNA helicase
OP863_18750	COG1011	Hydrolase
OP863_18755	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
OP863_18760	COG3159	Protein conserved in bacteria
OP863_18765	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OP863_18770	COG5567	small periplasmic lipoprotein
OP863_18775	COG1965	Belongs to the frataxin family
OP863_18780	COG3072	Adenylate cyclase
OP863_18785	COG0181	hydroxymethylbilane synthase activity
OP863_18790	COG1587	Uroporphyrinogen-III synthase
OP863_18795	COG2959	enzyme of heme biosynthesis
OP863_18800	COG3071	HemY protein
OP863_18840	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OP863_18845	COG2244	polysaccharide biosynthetic process
OP863_18850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OP863_18855	COG0456	acetyltransferase
OP863_18860	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
OP863_18865	COG1088	dTDP-glucose 4,6-dehydratase activity
OP863_18870	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
OP863_18875	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
OP863_18880	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
OP863_18885	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OP863_18890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
OP863_18895	COG3118	belongs to the thioredoxin family
OP863_18905	COG0248	Ppx GppA phosphatase
OP863_18915	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OP863_18925	COG3121	Chaperone
OP863_18940	COG3121	Chaperone
OP863_18970	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OP863_18975	COG0583	DNA-binding transcription factor activity
OP863_18980	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
OP863_18985	COG0129	dihydroxy-acid dehydratase activity
OP863_18990	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OP863_18995	COG3978	acetolactate synthase activity
OP863_19015	COG3085	chromosome segregation
OP863_19020	COG0583	DNA-binding transcription factor activity
OP863_19065	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
OP863_19075	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OP863_19090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OP863_19100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OP863_19100	COG0678	peroxiredoxin activity
OP863_19105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OP863_19145	COG1629	transport
OP863_19150	COG0165	Argininosuccinate lyase
OP863_19155	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OP863_19170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OP863_19180	COG0527	aspartate kinase activity
OP863_19180	COG0460	homoserine dehydrogenase
OP863_19185	COG0626	cystathionine gamma-synthase activity
OP863_19190	COG3060	This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis
OP863_19195	COG0254	rRNA binding
OP863_19200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OP863_19205	COG1609	Transcriptional regulator
OP863_19210	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OP863_19215	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OP863_19220	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OP863_19225	COG1575	Belongs to the MenA family. Type 1 subfamily
OP863_19230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OP863_19235	COG3074	FtsZ-dependent cytokinesis
OP863_19240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OP863_19245	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OP863_19250	COG1494	fructose-1,6-bisphosphatase
OP863_19255	COG2814	Major facilitator Superfamily
OP863_19265	COG3152	Membrane
OP863_19285	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
OP863_19295	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
OP863_19300	COG3678	ATP-independent chaperone mediated protein folding
OP863_19305	COG0745	RESPONSE REGULATOR receiver
OP863_19310	COG2205	protein histidine kinase activity
OP863_19315	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
OP863_19315	COG2169	Transcriptional regulator
OP863_19320	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OP863_19325	COG1045	serine acetyltransferase
OP863_19330	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OP863_19340	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OP863_19345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OP863_19350	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OP863_19355	COG4942	peptidase
OP863_19360	COG2861	carbohydrate metabolic process
OP863_19365	COG1063	alcohol dehydrogenase
OP863_19370	COG0156	8-amino-7-oxononanoate synthase activity
OP863_19375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OP863_19380	COG0859	PFAM glycosyl transferase family 9
OP863_19385	COG0859	PFAM glycosyl transferase family 9
OP863_19390	COG1519	Transferase
OP863_19405	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OP863_19410	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OP863_19415	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OP863_19420	COG2003	Belongs to the UPF0758 family
OP863_19425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OP863_19430	COG0756	dUTP diphosphatase activity
OP863_19435	COG1309	transcriptional regulator
OP863_19450	COG1561	YicC-like family, N-terminal region
OP863_19455	COG0519	Catalyzes the synthesis of GMP from XMP
OP863_19480	COG5001	Diguanylate cyclase
OP863_19485	COG1024	Enoyl-CoA hydratase
OP863_19500	COG2860	membrane
OP863_19505	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OP863_19515	COG1758	RNA polymerase activity
OP863_19520	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OP863_19525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OP863_19530	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OP863_19535	COG0786	glutamate:sodium symporter activity
OP863_19540	COG2233	PERMEase
OP863_19545	COG2982	Protein involved in outer membrane biogenesis
OP863_19560	COG3423	Transcriptional regulator
OP863_19565	COG0456	acetyltransferase
OP863_19570	COG1490	D-aminoacyl-tRNA deacylase activity
OP863_19575	COG1295	ribonuclease BN
OP863_19580	COG1011	Hydrolase
OP863_19595	COG3852	Histidine kinase
OP863_19605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OP863_19610	COG3078	GTPase activator activity
OP863_19615	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OP863_19620	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OP863_19620	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OP863_19625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OP863_19630	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OP863_19635	COG3084	Protein conserved in bacteria
OP863_19645	COG1763	Mo-molybdopterin cofactor biosynthetic process
OP863_19670	COG2186	Transcriptional regulator
OP863_19675	COG0477	Major facilitator Superfamily
OP863_19680	COG1609	Transcriptional regulator
OP863_19685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OP863_19690	COG1879	ABC-type sugar transport system periplasmic component
OP863_19695	COG1172	Belongs to the binding-protein-dependent transport system permease family
OP863_19705	COG1869	D-ribose catabolic process
OP863_19710	COG3158	transport of potassium into the cell
OP863_19715	COG0714	Associated with various cellular activities
OP863_19720	COG2425	protein containing a von Willebrand factor type A (vWA) domain
OP863_19730	COG2502	aspartate--ammonia ligase
OP863_19735	COG1522	sequence-specific DNA binding
OP863_19740	COG0716	FMN binding
OP863_19745	COG0445	tRNA wobble uridine modification
OP863_19750	COG0357	Ribosomal RNA small subunit methyltransferase G
OP863_19755	COG3312	ion transport
OP863_19760	COG0356	it plays a direct role in the translocation of protons across the membrane
OP863_19770	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OP863_19775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OP863_19780	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OP863_19790	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OP863_19795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OP863_19800	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OP863_19810	COG0659	secondary active sulfate transmembrane transporter activity
OP863_19815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
OP863_19820	COG0573	inorganic phosphate transmembrane transporter activity
OP863_19825	COG0581	inorganic phosphate transmembrane transporter activity
OP863_19835	COG0704	Plays a role in the regulation of phosphate uptake
OP863_19845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OP863_19850	COG0765	amino acid transport
OP863_19855	COG0765	amino acid transport
OP863_19860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OP863_19865	COG2252	PERMEase
OP863_19875	COG4566	intracellular signal transduction
OP863_19880	COG4191	Histidine kinase
OP863_19885	COG0431	NADPH-dependent FMN reductase
OP863_19890	COG0840	transmembrane signaling receptor activity
OP863_19895	COG2011	ABC-type metal ion transport system permease component
OP863_19910	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OP863_19915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OP863_19920	COG0706	membrane insertase activity
OP863_19930	COG0594	ribonuclease P activity
OP863_19935	COG0230	Belongs to the bacterial ribosomal protein bL34 family