locus-tag	class	description
LO772_00040	COG4977	sequence-specific DNA binding
LO772_00060	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LO772_00060	COG5479	isomerase activity
LO772_00230	COG2201	protein-glutamate methylesterase activity
LO772_00235	COG4585	Histidine kinase
LO772_00240	COG0577	efflux transmembrane transporter activity
LO772_00240	COG1136	(ABC) transporter
LO772_00245	COG0577	efflux transmembrane transporter activity
LO772_00245	COG1136	(ABC) transporter
LO772_00265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_00280	COG2723	6-phospho-beta-galactosidase activity
LO772_00290	COG2814	Major facilitator Superfamily
LO772_00330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_00335	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_00345	COG1116	anion transmembrane transporter activity
LO772_00350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO772_00380	COG0601	transmembrane transport
LO772_00390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_00395	COG1414	Transcriptional regulator
LO772_00415	COG2267	carboxylic ester hydrolase activity
LO772_00460	COG2267	carboxylic ester hydrolase activity
LO772_00495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_00510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_00535	COG0444	Belongs to the ABC transporter superfamily
LO772_00540	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO772_00545	COG0601	transmembrane transport
LO772_00550	COG0747	negative chemotaxis
LO772_00560	COG1959	2 iron, 2 sulfur cluster binding
LO772_00585	COG2197	response regulator
LO772_00590	COG4585	Histidine kinase
LO772_00665	COG4106	trans-aconitate 2-methyltransferase activity
LO772_00675	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LO772_00695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LO772_00705	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_00710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LO772_00715	COG0604	alcohol dehydrogenase
LO772_00715	COG3321	synthase
LO772_00745	COG1051	belongs to the nudix hydrolase family
LO772_00750	COG2132	Multicopper oxidase
LO772_00760	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LO772_00800	COG0477	Major facilitator Superfamily
LO772_00815	COG1842	Phage shock protein A
LO772_00825	COG0501	Belongs to the peptidase M48B family
LO772_00845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_00850	COG1396	sequence-specific DNA binding
LO772_00855	COG0740	serine-type endopeptidase activity
LO772_00860	COG0740	serine-type endopeptidase activity
LO772_00870	COG1116	anion transmembrane transporter activity
LO772_00880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO772_00885	COG0601	transmembrane transport
LO772_00895	COG1652	LysM domain
LO772_00965	COG0587	DNA-directed DNA polymerase activity
LO772_00980	COG1960	acyl-CoA dehydrogenase activity
LO772_00985	COG1960	acyl-CoA dehydrogenase activity
LO772_01030	COG0714	Associated with various cellular activities
LO772_01035	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LO772_01050	COG1397	ADP-ribosylglycohydrolase
LO772_01060	COG0583	DNA-binding transcription factor activity
LO772_01090	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_01095	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_01110	COG3250	beta-galactosidase activity
LO772_01130	COG1674	ftsk spoiiie
LO772_01145	COG3030	protein affecting phage T7 exclusion by the F plasmid
LO772_01150	COG1216	Glycosyl transferase, family 2
LO772_01155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO772_01165	COG1574	metal-dependent hydrolase with the TIM-barrel fold
LO772_01195	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LO772_01245	COG2318	DinB family
LO772_01250	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_01265	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_01280	COG0714	Associated with various cellular activities
LO772_01290	COG1595	DNA-templated transcription, initiation
LO772_01315	COG4638	Rieske (2fe-2S)
LO772_01320	COG1960	acyl-CoA dehydrogenase activity
LO772_01325	COG1960	acyl-CoA dehydrogenase activity
LO772_01390	COG0739	heme binding
LO772_01390	COG0741	lytic transglycosylase activity
LO772_01390	COG1196	nuclear chromosome segregation
LO772_01465	COG0714	Associated with various cellular activities
LO772_01480	COG0488	(ABC) transporter
LO772_01500	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LO772_01515	COG2801	Transposase and inactivated derivatives
LO772_01515	COG3415	Transposase
LO772_01565	COG0667	Aldo Keto reductase
LO772_01570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO772_01595	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LO772_01600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LO772_01615	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_01640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_01645	COG3251	PFAM MbtH domain protein
LO772_01665	COG1609	Transcriptional regulator
LO772_01695	COG1012	belongs to the aldehyde dehydrogenase family
LO772_01715	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_01725	COG2188	Transcriptional regulator
LO772_01735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_01740	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_01745	COG1024	Enoyl-CoA hydratase
LO772_01755	COG0747	negative chemotaxis
LO772_01760	COG0583	DNA-binding transcription factor activity
LO772_01770	COG1053	succinate dehydrogenase
LO772_01775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LO772_01820	COG1309	transcriptional regulator
LO772_01835	COG1132	(ABC) transporter
LO772_01840	COG1132	(ABC) transporter
LO772_01840	COG2375	cellular response to nickel ion
LO772_01875	COG3433	isochorismatase activity
LO772_01875	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_01875	COG2226	methyltransferase
LO772_01880	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LO772_01880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_01885	COG1021	2,3-dihydroxybenzoate-AMP ligase
LO772_01895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_01900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LO772_01905	COG1942	4-Oxalocrotonate Tautomerase
LO772_01920	COG4172	Belongs to the ABC transporter superfamily
LO772_01925	COG4171	peptide transport system, permease
LO772_01935	COG0747	negative chemotaxis
LO772_01950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_01970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_01980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO772_01990	COG0747	negative chemotaxis
LO772_02005	COG3321	synthase
LO772_02005	COG0604	alcohol dehydrogenase
LO772_02010	COG3321	synthase
LO772_02010	COG0604	alcohol dehydrogenase
LO772_02025	COG0508	dehydrogenase complex catalyzes the overall conversion of
LO772_02040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LO772_02045	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LO772_02060	COG1672	PFAM Archaeal ATPase
LO772_02060	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LO772_02110	COG0604	alcohol dehydrogenase
LO772_02110	COG3321	synthase
LO772_02110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_02110	COG4221	oxidoreductase activity
LO772_02120	COG2070	2-Nitropropane dioxygenase
LO772_02120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LO772_02125	COG2409	Drug exporters of the RND superfamily
LO772_02130	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LO772_02140	COG1285	pathogenesis
LO772_02150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_02170	COG1024	Enoyl-CoA hydratase
LO772_02175	COG0549	Belongs to the carbamate kinase family
LO772_02205	COG1012	belongs to the aldehyde dehydrogenase family
LO772_02230	COG4638	Rieske (2fe-2S)
LO772_02245	COG0300	oxidoreductase activity
LO772_02255	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LO772_02270	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LO772_02310	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_02345	COG0583	DNA-binding transcription factor activity
LO772_02395	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_02400	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_02405	COG2124	cytochrome p450
LO772_02445	COG1012	belongs to the aldehyde dehydrogenase family
LO772_02450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_02455	COG0657	acetylesterase activity
LO772_02460	COG1960	acyl-CoA dehydrogenase activity
LO772_02480	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_02490	COG1024	Enoyl-CoA hydratase
LO772_02495	COG1024	Enoyl-CoA hydratase
LO772_02500	COG1802	Transcriptional regulator
LO772_02505	COG1024	Enoyl-CoA hydratase
LO772_02515	COG1024	Enoyl-CoA hydratase
LO772_02555	COG1960	acyl-CoA dehydrogenase activity
LO772_02570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_02570	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LO772_02570	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LO772_02570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_02575	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_02620	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LO772_02640	COG2814	Major facilitator Superfamily
LO772_02645	COG1309	transcriptional regulator
LO772_02665	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_02680	COG1960	acyl-CoA dehydrogenase activity
LO772_02690	COG1309	transcriptional regulator
LO772_02710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_02725	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO772_02730	COG0601	transmembrane transport
LO772_02750	COG2233	PERMEase
LO772_02760	COG1335	isochorismatase
LO772_02770	COG0531	amino acid
LO772_02775	COG3540	Alkaline phosphatase
LO772_02790	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_02795	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_02805	COG1472	Belongs to the glycosyl hydrolase 3 family
LO772_02825	COG0435	Glutathione S-transferase
LO772_02830	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_02835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO772_02840	COG1228	amidohydrolase
LO772_02850	COG4638	Rieske (2fe-2S)
LO772_02895	COG0509	glycine decarboxylation via glycine cleavage system
LO772_02905	COG2814	Major facilitator Superfamily
LO772_02910	COG1309	transcriptional regulator
LO772_02935	COG1309	transcriptional regulator
LO772_02950	COG0439	Biotin carboxylase
LO772_02955	COG1132	(ABC) transporter
LO772_02960	COG2186	Transcriptional regulator
LO772_02975	COG0443	Heat shock 70 kDa protein
LO772_02980	COG1309	transcriptional regulator
LO772_02995	COG0517	IMP dehydrogenase activity
LO772_02995	COG0516	GMP reductase activity
LO772_03015	COG0640	Transcriptional regulator
LO772_03025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LO772_03040	COG0657	acetylesterase activity
LO772_03060	COG0166	Belongs to the GPI family
LO772_03070	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_03155	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_03230	COG4106	trans-aconitate 2-methyltransferase activity
LO772_03275	COG0667	Aldo Keto reductase
LO772_03280	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_03310	COG0535	radical SAM domain protein
LO772_03320	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LO772_03355	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_03400	COG1278	Cold shock
LO772_03410	COG0747	negative chemotaxis
LO772_03420	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO772_03430	COG0477	Major facilitator Superfamily
LO772_03435	COG0667	Aldo Keto reductase
LO772_03455	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LO772_03465	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LO772_03490	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_03525	COG2124	cytochrome p450
LO772_03545	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
LO772_03560	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_03580	COG0783	Belongs to the Dps family
LO772_03600	COG1846	Transcriptional regulator
LO772_03630	COG2255	four-way junction helicase activity
LO772_03655	COG0829	nickel cation binding
LO772_03660	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LO772_03665	COG0830	nickel cation binding
LO772_03670	COG0804	urea catabolic process
LO772_03675	COG0832	Belongs to the urease beta subunit family
LO772_03695	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LO772_03700	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LO772_03735	COG2409	Drug exporters of the RND superfamily
LO772_03745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LO772_03750	COG1302	Protein conserved in bacteria
LO772_03755	COG0386	Belongs to the glutathione peroxidase family
LO772_03760	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LO772_03770	COG1215	transferase activity, transferring glycosyl groups
LO772_03800	COG1960	acyl-CoA dehydrogenase activity
LO772_03855	COG0433	COG0433 Predicted ATPase
LO772_03855	COG1674	ftsk spoiiie
LO772_03885	COG0464	growth
LO772_03915	COG1940	carbohydrate kinase activity
LO772_03940	COG2813	Specifically methylates the guanine in position
LO772_03945	COG3800	Transcriptional regulator
LO772_03945	COG1396	sequence-specific DNA binding
LO772_03960	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_03965	COG1960	acyl-CoA dehydrogenase activity
LO772_03985	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_04000	COG2124	cytochrome p450
LO772_04010	COG0604	alcohol dehydrogenase
LO772_04045	COG2723	6-phospho-beta-galactosidase activity
LO772_04075	COG1404	Belongs to the peptidase S8 family
LO772_04095	COG1309	transcriptional regulator
LO772_04110	COG1126	abc transporter atp-binding protein
LO772_04115	COG0765	amino acid transport
LO772_04120	COG0765	amino acid transport
LO772_04130	COG2409	Drug exporters of the RND superfamily
LO772_04135	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_04150	COG1191	sigma factor activity
LO772_04160	COG2197	response regulator
LO772_04165	COG4585	Histidine kinase
LO772_04170	COG2409	Drug exporters of the RND superfamily
LO772_04175	COG3290	protein histidine kinase activity
LO772_04185	COG0367	asparagine synthase
LO772_04215	COG1397	ADP-ribosylglycohydrolase
LO772_04240	COG3442	glutamine amidotransferase
LO772_04255	COG1309	transcriptional regulator
LO772_04265	COG0640	Transcriptional regulator
LO772_04275	COG4941	Belongs to the sigma-70 factor family
LO772_04280	COG3795	YCII-related domain
LO772_04365	COG2124	cytochrome p450
LO772_04390	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_04410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_04430	COG0477	Major facilitator Superfamily
LO772_04455	COG2197	response regulator
LO772_04460	COG4585	Histidine kinase
LO772_04490	COG0697	spore germination
LO772_04500	COG0204	Acyl-transferase
LO772_04500	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_04510	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LO772_04535	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LO772_04540	COG0667	Aldo Keto reductase
LO772_04550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LO772_04565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LO772_04585	COG1595	DNA-templated transcription, initiation
LO772_04590	COG2409	Drug exporters of the RND superfamily
LO772_04605	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LO772_04645	COG1191	sigma factor activity
LO772_04670	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LO772_04695	COG0514	ATP-dependent DNA helicase (RecQ)
LO772_04705	COG2271	Major facilitator Superfamily
LO772_04715	COG1755	Isoprenylcysteine carboxyl methyltransferase
LO772_04760	COG3959	Transketolase, thiamine diphosphate binding domain
LO772_04770	COG0693	protein deglycase activity
LO772_04790	COG0387	Pfam Sodium calcium exchanger
LO772_04810	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LO772_04815	COG0517	IMP dehydrogenase activity
LO772_04820	COG1793	dna ligase
LO772_04895	COG2267	carboxylic ester hydrolase activity
LO772_04900	COG2146	nitrite reductase [NAD(P)H] activity
LO772_04910	COG4638	Rieske (2fe-2S)
LO772_04930	COG1129	ABC transporter
LO772_04935	COG4211	Belongs to the binding-protein-dependent transport system permease family
LO772_04970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LO772_05035	COG1309	transcriptional regulator
LO772_05055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LO772_05055	COG2308	Evidence 4 Homologs of previously reported genes of
LO772_05120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LO772_05150	COG2226	methyltransferase
LO772_05170	COG0702	epimerase
LO772_05205	COG0477	Major facilitator Superfamily
LO772_05240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LO772_05255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LO772_05280	COG1522	sequence-specific DNA binding
LO772_05300	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_05305	COG2508	Transcriptional regulator
LO772_05320	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LO772_05325	COG0140	phosphoribosyl-ATP diphosphatase activity
LO772_05330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LO772_05335	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LO772_05335	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LO772_05350	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LO772_05360	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LO772_05365	COG0242	peptide deformylase activity
LO772_05380	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LO772_05395	COG1758	RNA polymerase activity
LO772_05410	COG0284	orotidine-5'-phosphate decarboxylase activity
LO772_05415	COG0167	dihydroorotate dehydrogenase activity
LO772_05420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LO772_05425	COG0505	Belongs to the CarA family
LO772_05435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LO772_05440	COG0540	Belongs to the ATCase OTCase family
LO772_05445	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LO772_05455	COG1609	Transcriptional regulator
LO772_05475	COG2211	Major facilitator Superfamily
LO772_05480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LO772_05485	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LO772_05490	COG0006	proline dipeptidase activity
LO772_05500	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LO772_05505	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LO772_05510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LO772_05515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LO772_05520	COG1683	Conserved Protein
LO772_05530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LO772_05535	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LO772_05545	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LO772_05560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LO772_05590	COG1063	alcohol dehydrogenase
LO772_05600	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_05610	COG0515	serine threonine protein kinase
LO772_05610	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LO772_05625	COG0488	(ABC) transporter
LO772_05640	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LO772_05675	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LO772_05680	COG0492	ferredoxin-NADP+ reductase activity
LO772_05685	COG1309	transcriptional regulator
LO772_05710	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LO772_05715	COG0254	rRNA binding
LO772_05730	COG1253	flavin adenine dinucleotide binding
LO772_05745	COG0180	Tryptophanyl-tRNA synthetase
LO772_05755	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_05765	COG0596	Alpha beta hydrolase
LO772_05770	COG0432	Pfam Uncharacterised protein family UPF0047
LO772_05775	COG0667	Aldo Keto reductase
LO772_05785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LO772_05815	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_05820	COG1309	transcriptional regulator
LO772_05825	COG0667	Aldo Keto reductase
LO772_05835	COG3973	AAA domain
LO772_05870	COG0726	polysaccharide deacetylase
LO772_05875	COG1132	(ABC) transporter
LO772_05950	COG2124	cytochrome p450
LO772_05955	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LO772_05990	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_05995	COG1960	acyl-CoA dehydrogenase activity
LO772_06000	COG0183	Belongs to the thiolase family
LO772_06005	COG1024	Enoyl-CoA hydratase
LO772_06015	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_06020	COG1960	acyl-CoA dehydrogenase activity
LO772_06025	COG1960	acyl-CoA dehydrogenase activity
LO772_06030	COG1024	Enoyl-CoA hydratase
LO772_06035	COG2186	Transcriptional regulator
LO772_06040	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_06075	COG1012	belongs to the aldehyde dehydrogenase family
LO772_06080	COG1012	belongs to the aldehyde dehydrogenase family
LO772_06135	COG1309	transcriptional regulator
LO772_06190	COG1960	acyl-CoA dehydrogenase activity
LO772_06205	COG1960	acyl-CoA dehydrogenase activity
LO772_06210	COG1960	acyl-CoA dehydrogenase activity
LO772_06220	COG1946	Acyl-CoA thioesterase
LO772_06225	COG0183	Belongs to the thiolase family
LO772_06230	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_06245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_06250	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_06260	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_06265	COG1024	Enoyl-CoA hydratase
LO772_06285	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_06295	COG0443	Heat shock 70 kDa protein
LO772_06335	COG1012	belongs to the aldehyde dehydrogenase family
LO772_06370	COG1309	transcriptional regulator
LO772_06375	COG0667	Aldo Keto reductase
LO772_06380	COG3415	Transposase
LO772_06380	COG2801	Transposase and inactivated derivatives
LO772_06405	COG1070	Carbohydrate kinase
LO772_06415	COG1070	Carbohydrate kinase
LO772_06425	COG1904	glucuronate isomerase
LO772_06435	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
LO772_06440	COG0657	acetylesterase activity
LO772_06475	COG0583	DNA-binding transcription factor activity
LO772_06485	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_06500	COG2226	methyltransferase
LO772_06525	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LO772_06525	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LO772_06540	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LO772_06570	COG1733	regulation of RNA biosynthetic process
LO772_06575	COG1024	Enoyl-CoA hydratase
LO772_06590	COG1181	Belongs to the D-alanine--D-alanine ligase family
LO772_06595	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LO772_06600	COG0745	RESPONSE REGULATOR receiver
LO772_06610	COG0640	Transcriptional regulator
LO772_06630	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LO772_06640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LO772_06715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LO772_06735	COG1960	acyl-CoA dehydrogenase activity
LO772_06740	COG1960	acyl-CoA dehydrogenase activity
LO772_06790	COG2197	response regulator
LO772_06815	COG2208	phosphoserine phosphatase activity
LO772_06860	COG1960	acyl-CoA dehydrogenase activity
LO772_06875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LO772_06875	COG4651	solute:proton antiporter activity
LO772_06885	COG1309	transcriptional regulator
LO772_06895	COG2188	Transcriptional regulator
LO772_06920	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LO772_06940	COG1181	Belongs to the D-alanine--D-alanine ligase family
LO772_06950	COG0596	Alpha beta hydrolase
LO772_06955	COG0477	Major facilitator Superfamily
LO772_07015	COG0183	Belongs to the thiolase family
LO772_07060	COG2895	sulfate adenylyltransferase (ATP) activity
LO772_07060	COG0529	Catalyzes the synthesis of activated sulfate
LO772_07065	COG0175	sulfate reduction
LO772_07070	COG1063	alcohol dehydrogenase
LO772_07090	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_07110	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LO772_07115	COG2188	Transcriptional regulator
LO772_07120	COG1012	belongs to the aldehyde dehydrogenase family
LO772_07125	COG0431	NADPH-dependent FMN reductase
LO772_07125	COG3976	FMN-binding domain protein
LO772_07125	COG1053	succinate dehydrogenase
LO772_07130	COG2084	Dehydrogenase
LO772_07145	COG3973	AAA domain
LO772_07200	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LO772_07205	COG1309	transcriptional regulator
LO772_07230	COG2986	histidine ammonia-lyase
LO772_07255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_07265	COG1414	Transcriptional regulator
LO772_07270	COG0431	NADPH-dependent FMN reductase
LO772_07290	COG0601	transmembrane transport
LO772_07300	COG1819	glycosyl
LO772_07310	COG4166	transmembrane transport
LO772_07320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO772_07350	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LO772_07360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO772_07380	COG3321	synthase
LO772_07380	COG0604	alcohol dehydrogenase
LO772_07385	COG0546	phosphoglycolate phosphatase activity
LO772_07400	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LO772_07415	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LO772_07425	COG3629	intracellular signal transduction
LO772_07425	COG3903	Transcriptional regulator
LO772_07435	COG0477	Major facilitator Superfamily
LO772_07445	COG2197	response regulator
LO772_07455	COG2409	Drug exporters of the RND superfamily
LO772_07465	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LO772_07470	COG1595	DNA-templated transcription, initiation
LO772_07495	COG1968	undecaprenyl-diphosphatase activity
LO772_07500	COG0747	negative chemotaxis
LO772_07510	COG0444	Belongs to the ABC transporter superfamily
LO772_07545	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
LO772_07555	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LO772_07560	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LO772_07565	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LO772_07580	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LO772_07605	COG4166	transmembrane transport
LO772_07610	COG0601	transmembrane transport
LO772_07615	COG4171	peptide transport system, permease
LO772_07625	COG0745	RESPONSE REGULATOR receiver
LO772_07635	COG0586	Pfam SNARE associated Golgi protein
LO772_07740	COG0270	DNA (cytosine-5-)-methyltransferase activity
LO772_07750	COG2376	Dihydroxyacetone kinase
LO772_07760	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LO772_07760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LO772_07760	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LO772_07765	COG1461	Dihydroxyacetone kinase
LO772_07770	COG2376	Dihydroxyacetone kinase
LO772_07775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LO772_07785	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
LO772_07805	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LO772_08180	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_08300	COG1652	LysM domain
LO772_08410	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LO772_08470	COG2340	Cysteine-rich secretory protein family
LO772_08480	COG0477	Major facilitator Superfamily
LO772_08500	COG0183	Belongs to the thiolase family
LO772_08525	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_08550	COG0477	Major facilitator Superfamily
LO772_08555	COG1960	acyl-CoA dehydrogenase activity
LO772_08570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LO772_08575	COG1309	transcriptional regulator
LO772_08580	COG1024	Enoyl-CoA hydratase
LO772_08600	COG1278	Cold shock
LO772_08605	COG0588	phosphoglycerate mutase activity
LO772_08620	COG0656	L-ascorbic acid biosynthetic process
LO772_08700	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LO772_08715	COG1309	transcriptional regulator
LO772_08720	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_08740	COG2814	Major facilitator Superfamily
LO772_08755	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LO772_08755	COG2308	Evidence 4 Homologs of previously reported genes of
LO772_08775	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_08790	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_08835	COG1657	PFAM Prenyltransferase squalene oxidase
LO772_08845	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LO772_08855	COG1562	ergosterol biosynthetic process
LO772_08860	COG4608	Belongs to the ABC transporter superfamily
LO772_08865	COG0444	Belongs to the ABC transporter superfamily
LO772_08875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO772_08880	COG0601	transmembrane transport
LO772_08885	COG5398	heme oxygenase
LO772_08900	COG2814	Major facilitator Superfamily
LO772_08910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LO772_08945	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LO772_08950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LO772_08995	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LO772_09000	COG0745	RESPONSE REGULATOR receiver
LO772_09015	COG1653	transport
LO772_09025	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LO772_09045	COG2409	Drug exporters of the RND superfamily
LO772_09075	COG0515	serine threonine protein kinase
LO772_09095	COG1119	ATPase activity
LO772_09135	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LO772_09180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_09195	COG2197	response regulator
LO772_09200	COG4585	Histidine kinase
LO772_09225	COG0804	urea catabolic process
LO772_09245	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LO772_09255	COG2124	cytochrome p450
LO772_09260	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LO772_09265	COG1162	GTPase activity
LO772_09290	COG0175	sulfate reduction
LO772_09310	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LO772_09315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO772_09345	COG0745	RESPONSE REGULATOR receiver
LO772_09375	COG2326	polyphosphate kinase activity
LO772_09395	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LO772_09400	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LO772_09425	COG3253	May function as heme-dependent peroxidase
LO772_09430	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
LO772_09440	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LO772_09450	COG2197	response regulator
LO772_09460	COG0183	Belongs to the thiolase family
LO772_09465	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO772_09465	COG1024	Enoyl-CoA hydratase
LO772_09480	COG0531	amino acid
LO772_09490	COG1595	DNA-templated transcription, initiation
LO772_09495	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LO772_09500	COG4213	ABC transporter substrate-binding protein
LO772_09510	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LO772_09515	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_09530	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_09550	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO772_09550	COG1902	pentaerythritol trinitrate reductase activity
LO772_09555	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_09560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LO772_09580	COG1595	DNA-templated transcription, initiation
LO772_09660	COG0235	Class ii aldolase
LO772_09665	COG1131	(ABC) transporter
LO772_09695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LO772_09700	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LO772_09710	COG2814	Major facilitator Superfamily
LO772_09735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LO772_09740	COG0531	amino acid
LO772_09745	COG0569	domain protein
LO772_09775	COG0756	dUTP diphosphatase activity
LO772_09785	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_09805	COG4152	abc transporter atp-binding protein
LO772_09810	COG1668	transmembrane transport
LO772_09820	COG2205	protein histidine kinase activity
LO772_09825	COG0745	RESPONSE REGULATOR receiver
LO772_09840	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LO772_09885	COG2313	pseudouridylate synthase activity
LO772_09890	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LO772_09900	COG0612	Peptidase, M16
LO772_09910	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LO772_09915	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LO772_09925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LO772_09935	COG0187	DNA topoisomerase II activity
LO772_09950	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LO772_09965	COG1131	(ABC) transporter
LO772_09995	COG0514	ATP-dependent DNA helicase (RecQ)
LO772_10025	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LO772_10040	COG0477	Major facilitator Superfamily
LO772_10060	COG0242	peptide deformylase activity
LO772_10065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LO772_10070	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LO772_10075	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LO772_10085	COG2755	lipolytic protein G-D-S-L family
LO772_10090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LO772_10105	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LO772_10110	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LO772_10115	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LO772_10130	COG0406	alpha-ribazole phosphatase activity
LO772_10135	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LO772_10145	COG2815	serine threonine protein kinase
LO772_10145	COG0515	serine threonine protein kinase
LO772_10150	COG2205	protein histidine kinase activity
LO772_10160	COG1126	abc transporter atp-binding protein
LO772_10170	COG0765	amino acid transport
LO772_10175	COG0765	amino acid transport
LO772_10210	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LO772_10300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LO772_10305	COG1121	(ABC) transporter
LO772_10315	COG0803	Belongs to the bacterial solute-binding protein 9 family
LO772_10330	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LO772_10335	COG0523	cobalamin synthesis protein
LO772_10340	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LO772_10345	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LO772_10370	COG1609	Transcriptional regulator
LO772_10380	COG1609	Transcriptional regulator
LO772_10405	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LO772_10420	COG2272	Belongs to the type-B carboxylesterase lipase family
LO772_10425	COG3507	Belongs to the glycosyl hydrolase 43 family
LO772_10440	COG0667	Aldo Keto reductase
LO772_10445	COG0604	alcohol dehydrogenase
LO772_10445	COG3321	synthase
LO772_10450	COG2267	carboxylic ester hydrolase activity
LO772_10475	COG3119	arylsulfatase activity
LO772_10510	COG3022	response to hydroperoxide
LO772_10525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LO772_10530	COG0515	serine threonine protein kinase
LO772_10545	COG1132	(ABC) transporter
LO772_10550	COG1132	(ABC) transporter
LO772_10560	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_10570	COG2030	dehydratase
LO772_10580	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_10585	COG0515	serine threonine protein kinase
LO772_10585	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LO772_10650	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_10655	COG0183	Belongs to the thiolase family
LO772_10670	COG0860	N-Acetylmuramoyl-L-alanine amidase
LO772_10685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_10705	COG2226	methyltransferase
LO772_10710	COG0438	transferase activity, transferring glycosyl groups
LO772_10715	COG1309	transcriptional regulator
LO772_10745	COG0604	alcohol dehydrogenase
LO772_10750	COG1024	Enoyl-CoA hydratase
LO772_10755	COG0427	acetyl-CoA hydrolase
LO772_10765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_10775	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_10805	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_10810	COG2072	flavoprotein involved in K transport
LO772_10815	COG4638	Rieske (2fe-2S)
LO772_10820	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_10830	COG1802	Transcriptional regulator
LO772_10835	COG1960	acyl-CoA dehydrogenase activity
LO772_10845	COG1024	Enoyl-CoA hydratase
LO772_10850	COG1960	acyl-CoA dehydrogenase activity
LO772_10855	COG1960	acyl-CoA dehydrogenase activity
LO772_10905	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LO772_10955	COG0659	secondary active sulfate transmembrane transporter activity
LO772_10970	COG1472	Belongs to the glycosyl hydrolase 3 family
LO772_11050	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LO772_11060	COG0395	ABC-type sugar transport system, permease component
LO772_11065	COG1175	transmembrane transport
LO772_11080	COG0667	Aldo Keto reductase
LO772_11085	COG0789	Transcriptional regulator
LO772_11100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO772_11105	COG1120	ATPase activity
LO772_11125	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LO772_11130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LO772_11135	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LO772_11190	COG1070	Carbohydrate kinase
LO772_11205	COG0358	DNA primase activity
LO772_11210	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LO772_11215	COG1191	sigma factor activity
LO772_11230	COG0792	nuclease activity
LO772_11240	COG1051	belongs to the nudix hydrolase family
LO772_11245	COG0681	Belongs to the peptidase S26 family
LO772_11255	COG0681	Belongs to the peptidase S26 family
LO772_11260	COG0335	large ribosomal subunit rRNA binding
LO772_11265	COG0336	Belongs to the RNA methyltransferase TrmD family
LO772_11270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LO772_11275	COG1837	Belongs to the UPF0109 family
LO772_11280	COG0228	four-way junction DNA binding
LO772_11285	COG0442	prolyl-tRNA aminoacylation
LO772_11300	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LO772_11340	COG1196	nuclear chromosome segregation
LO772_11350	COG2340	Cysteine-rich secretory protein family
LO772_11355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LO772_11360	COG0571	ribonuclease III activity
LO772_11365	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LO772_11380	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LO772_11385	COG0742	ribosomal rna small subunit methyltransferase
LO772_11395	COG1461	Dihydroxyacetone kinase
LO772_11400	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LO772_11405	COG0351	phosphomethylpyrimidine kinase
LO772_11425	COG1181	Belongs to the D-alanine--D-alanine ligase family
LO772_11430	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LO772_11440	COG1920	GTP binding
LO772_11450	COG0776	regulation of translation
LO772_11460	COG0066	3-isopropylmalate dehydratase activity
LO772_11465	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LO772_11490	COG2018	Roadblock/LC7 domain
LO772_11495	COG0642	Histidine kinase
LO772_11505	COG0179	Fumarylacetoacetate (FAA) hydrolase
LO772_11510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LO772_11530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LO772_11535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LO772_11540	COG0473	3-isopropylmalate dehydrogenase activity
LO772_11545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LO772_11585	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LO772_11590	COG0440	acetolactate synthase activity
LO772_11605	COG2133	pyrroloquinoline quinone binding
LO772_11610	COG1672	PFAM Archaeal ATPase
LO772_11610	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LO772_11620	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LO772_11630	COG0154	amidase activity
LO772_11635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LO772_11645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LO772_11675	COG2188	Transcriptional regulator
LO772_11700	COG0596	Alpha beta hydrolase
LO772_11705	COG0482	sulfurtransferase activity
LO772_11735	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LO772_11740	COG0509	glycine decarboxylation via glycine cleavage system
LO772_11745	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LO772_11755	COG3654	unkown
LO772_11760	COG0477	Major facilitator Superfamily
LO772_11770	COG1376	ErfK ybiS ycfS ynhG family protein
LO772_11785	COG2365	Tyrosine phosphatase family
LO772_11830	COG0366	Alpha amylase catalytic
LO772_11835	COG0366	Alpha amylase catalytic
LO772_11840	COG3281	Trehalose synthase
LO772_11845	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LO772_11880	COG0183	Belongs to the thiolase family
LO772_11885	COG0346	lactoylglutathione lyase activity
LO772_11940	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO772_11955	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
LO772_12030	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LO772_12030	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LO772_12040	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO772_12065	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LO772_12070	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LO772_12075	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LO772_12080	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LO772_12085	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LO772_12090	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LO772_12095	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LO772_12120	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LO772_12135	COG2890	protein-(glutamine-N5) methyltransferase activity
LO772_12140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LO772_12145	COG0254	rRNA binding
LO772_12155	COG0083	homoserine kinase activity
LO772_12160	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LO772_12165	COG0460	homoserine dehydrogenase
LO772_12170	COG0019	diaminopimelate decarboxylase activity
LO772_12175	COG0018	arginyl-trna synthetase
LO772_12190	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LO772_12310	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LO772_12310	COG4106	trans-aconitate 2-methyltransferase activity
LO772_12350	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO772_12390	COG1902	pentaerythritol trinitrate reductase activity
LO772_12425	COG0300	oxidoreductase activity
LO772_12445	COG0559	Belongs to the binding-protein-dependent transport system permease family
LO772_12460	COG2508	Transcriptional regulator
LO772_12470	COG4166	transmembrane transport
LO772_12500	COG0582	viral genome integration into host DNA
LO772_12515	COG1372	Participates in initiation and elongation during chromosome replication
LO772_12515	COG0305	Participates in initiation and elongation during chromosome replication
LO772_12580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LO772_12590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LO772_12595	COG2172	sigma factor antagonist activity
LO772_12610	COG1597	lipid kinase activity
LO772_12625	COG0156	8-amino-7-oxononanoate synthase activity
LO772_12640	COG2188	Transcriptional regulator
LO772_12645	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LO772_12650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LO772_12655	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
LO772_12660	COG1595	DNA-templated transcription, initiation
LO772_12675	COG5662	AntiSigma factor
LO772_12680	COG1595	DNA-templated transcription, initiation
LO772_12690	COG2135	peptidase activity
LO772_12695	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LO772_12720	COG0483	inositol monophosphate 1-phosphatase activity
LO772_12730	COG0753	catalase activity
LO772_12765	COG1615	UPF0182 protein
LO772_12775	COG3480	Lon protease (S16) C-terminal proteolytic domain
LO772_12785	COG0314	molybdopterin synthase activity
LO772_12790	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LO772_12830	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LO772_12875	COG0210	DNA helicase
LO772_12940	COG0513	Belongs to the DEAD box helicase family
LO772_12950	COG1432	Conserved Protein
LO772_12960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO772_12970	COG0613	PHP domain protein
LO772_12985	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LO772_13000	COG0589	response to stress
LO772_13015	COG0598	Magnesium transport protein CorA
LO772_13025	COG1960	acyl-CoA dehydrogenase activity
LO772_13030	COG1228	amidohydrolase
LO772_13045	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LO772_13065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LO772_13080	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LO772_13090	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LO772_13090	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LO772_13095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LO772_13105	COG0424	maF-like protein
LO772_13130	COG4770	biotin carboxylase activity
LO772_13155	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LO772_13160	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_13200	COG1012	belongs to the aldehyde dehydrogenase family
LO772_13205	COG1012	belongs to the aldehyde dehydrogenase family
LO772_13215	COG1595	DNA-templated transcription, initiation
LO772_13220	COG0745	RESPONSE REGULATOR receiver
LO772_13225	COG2205	protein histidine kinase activity
LO772_13250	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LO772_13255	COG0583	DNA-binding transcription factor activity
LO772_13260	COG2814	Major facilitator Superfamily
LO772_13275	COG1079	Belongs to the binding-protein-dependent transport system permease family
LO772_13280	COG4603	Belongs to the binding-protein-dependent transport system permease family
LO772_13285	COG3845	ABC transporter
LO772_13290	COG1744	ABC transporter substrate-binding protein PnrA-like
LO772_13295	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LO772_13295	COG1473	amidohydrolase
LO772_13315	COG2009	succinate dehydrogenase
LO772_13330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LO772_13345	COG1674	ftsk spoiiie
LO772_13440	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LO772_13440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LO772_13450	COG0515	serine threonine protein kinase
LO772_13465	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LO772_13470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LO772_13475	COG0673	inositol 2-dehydrogenase activity
LO772_13490	COG0193	aminoacyl-tRNA hydrolase activity
LO772_13495	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LO772_13500	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LO772_13505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LO772_13520	COG1309	transcriptional regulator
LO772_13530	COG4106	trans-aconitate 2-methyltransferase activity
LO772_13535	COG1846	Transcriptional regulator
LO772_13540	COG1252	NADH dehydrogenase
LO772_13545	COG1595	DNA-templated transcription, initiation
LO772_13555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LO772_13560	COG2124	cytochrome p450
LO772_13570	COG1686	Belongs to the peptidase S11 family
LO772_13575	COG1295	ribonuclease BN
LO772_13585	COG0180	Tryptophanyl-tRNA synthetase
LO772_13590	COG1834	amidinotransferase
LO772_13595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LO772_13605	COG1522	sequence-specific DNA binding
LO772_13610	COG0039	L-malate dehydrogenase activity
LO772_13645	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LO772_13655	COG0138	bifunctional purine biosynthesis protein purh
LO772_13695	COG0045	succinate-CoA ligase (ADP-forming) activity
LO772_13700	COG3552	Protein containing von Willebrand factor type A (VWA) domain
LO772_13710	COG0714	Associated with various cellular activities
LO772_13725	COG2197	response regulator
LO772_13765	COG2197	response regulator
LO772_13790	COG1703	isobutyryl-CoA mutase activity
LO772_13790	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LO772_13790	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
LO772_13795	COG0738	Major facilitator superfamily
LO772_13800	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LO772_13800	COG0519	Catalyzes the synthesis of GMP from XMP
LO772_13805	COG1605	Chorismate mutase
LO772_13825	COG0515	serine threonine protein kinase
LO772_13830	COG0515	serine threonine protein kinase
LO772_13830	COG2815	serine threonine protein kinase
LO772_13835	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LO772_13840	COG0516	GMP reductase activity
LO772_13855	COG1595	DNA-templated transcription, initiation
LO772_13860	COG2197	response regulator
LO772_13870	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_13875	COG0459	protein refolding
LO772_13880	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LO772_13910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LO772_13915	COG0802	atpase or kinase
LO772_13925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LO772_13940	COG0736	holo-[acyl-carrier-protein] synthase activity
LO772_13945	COG0697	spore germination
LO772_13950	COG1846	Transcriptional regulator
LO772_13960	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LO772_13965	COG1072	(Pantothenic acid kinase))
LO772_13970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LO772_13975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LO772_13980	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LO772_13990	COG0101	tRNA pseudouridine synthase activity
LO772_13995	COG0203	ribosomal protein L17
LO772_14005	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LO772_14010	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LO772_14015	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LO772_14020	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LO772_14025	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LO772_14040	COG0563	adenylate kinase activity
LO772_14050	COG0200	Binds to the 23S rRNA
LO772_14055	COG1841	ribosomal large subunit assembly
LO772_14060	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LO772_14065	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LO772_14070	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LO772_14075	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LO772_14080	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LO772_14085	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LO772_14090	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LO772_14095	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LO772_14100	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LO772_14105	COG0255	Belongs to the universal ribosomal protein uL29 family
LO772_14110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LO772_14115	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LO772_14120	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LO772_14125	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LO772_14130	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LO772_14135	COG0089	rRNA binding
LO772_14140	COG0088	Forms part of the polypeptide exit tunnel
LO772_14145	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LO772_14150	COG0051	transcription antitermination factor activity, RNA binding
LO772_14155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LO772_14160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LO772_14165	COG0049	tRNA binding
LO772_14170	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LO772_14175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LO772_14180	COG0085	RNA polymerase activity
LO772_14185	COG0222	ribosome binding
LO772_14190	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LO772_14195	COG0081	regulation of translation
LO772_14200	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LO772_14210	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LO772_14220	COG0436	Aminotransferase
LO772_14225	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LO772_14230	COG0477	Major facilitator Superfamily
LO772_14240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LO772_14250	COG2030	dehydratase
LO772_14255	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LO772_14280	COG0714	Associated with various cellular activities
LO772_14330	COG0577	efflux transmembrane transporter activity
LO772_14330	COG1136	(ABC) transporter
LO772_14375	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO772_14380	COG1846	Transcriptional regulator
LO772_14395	COG1666	GTP binding
LO772_14405	COG3304	Inner membrane component domain
LO772_14410	COG0501	Belongs to the peptidase M48B family
LO772_14425	COG0713	ATP synthesis coupled electron transport
LO772_14430	COG0839	Belongs to the complex I subunit 6 family
LO772_14435	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LO772_14440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LO772_14445	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LO772_14450	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LO772_14455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LO772_14460	COG4585	Histidine kinase
LO772_14465	COG2201	protein-glutamate methylesterase activity
LO772_14470	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LO772_14470	COG0674	pyruvate-flavodoxin oxidoreductase activity
LO772_14475	COG1013	pyruvate-flavodoxin oxidoreductase activity
LO772_14585	COG0142	geranyltranstransferase activity
LO772_14600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LO772_14615	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LO772_14620	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LO772_14625	COG1034	ATP synthesis coupled electron transport
LO772_14630	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LO772_14640	COG0649	NAD binding
LO772_14645	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LO772_14650	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LO772_14660	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
LO772_14680	COG1309	transcriptional regulator
LO772_14685	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_14720	COG2258	MOSC domain
LO772_14725	COG2226	methyltransferase
LO772_14735	COG1228	amidohydrolase
LO772_14740	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LO772_14750	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LO772_14770	COG1301	dicarboxylic acid transport
LO772_14780	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LO772_14790	COG0163	prenyltransferase activity
LO772_14805	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LO772_14810	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LO772_14875	COG2318	DinB family
LO772_14925	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_14945	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LO772_14950	COG1333	cytochrome c biogenesis protein
LO772_14955	COG0785	Cytochrome C biogenesis protein
LO772_14960	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LO772_14965	COG0406	alpha-ribazole phosphatase activity
LO772_14970	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LO772_14985	COG2175	clavaminate synthase activity
LO772_15000	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_15005	COG0778	Nitroreductase
LO772_15015	COG1690	Belongs to the RtcB family
LO772_15040	COG0745	RESPONSE REGULATOR receiver
LO772_15045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO772_15045	COG2146	nitrite reductase [NAD(P)H] activity
LO772_15075	COG2223	nitrite transmembrane transporter activity
LO772_15090	COG0477	Major facilitator Superfamily
LO772_15130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_15155	COG0259	pyridoxamine-phosphate oxidase activity
LO772_15165	COG2890	protein-(glutamine-N5) methyltransferase activity
LO772_15170	COG0247	lactate metabolic process
LO772_15170	COG0277	FAD linked oxidase domain protein
LO772_15175	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LO772_15190	COG1595	DNA-templated transcription, initiation
LO772_15230	COG2814	Major facilitator Superfamily
LO772_15240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LO772_15245	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
LO772_15280	COG1131	(ABC) transporter
LO772_15285	COG1061	Type III restriction enzyme res subunit
LO772_15290	COG3973	AAA domain
LO772_15300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LO772_15380	COG1278	Cold shock
LO772_15385	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LO772_15390	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LO772_15395	COG1215	transferase activity, transferring glycosyl groups
LO772_15445	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
LO772_15470	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO772_15620	COG1063	alcohol dehydrogenase
LO772_15685	COG3842	ATPase activity
LO772_15695	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LO772_15700	COG0215	cysteine-tRNA ligase activity
LO772_15705	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LO772_15710	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LO772_15715	COG1329	Transcriptional regulator
LO772_15730	COG5002	protein histidine kinase activity
LO772_15735	COG0588	phosphoglycerate mutase activity
LO772_15745	COG0438	transferase activity, transferring glycosyl groups
LO772_15785	COG1733	regulation of RNA biosynthetic process
LO772_15800	COG1490	D-aminoacyl-tRNA deacylase activity
LO772_15810	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LO772_15820	COG1316	TRANSCRIPTIONal
LO772_15825	COG4044	May play a role in the intracellular transport of hydrophobic ligands
LO772_15850	COG2897	thiosulfate sulfurtransferase activity
LO772_15880	COG0745	RESPONSE REGULATOR receiver
LO772_15885	COG1609	Transcriptional regulator
LO772_15905	COG0456	acetyltransferase
LO772_15910	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LO772_15945	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LO772_15950	COG0306	phosphate transporter
LO772_15960	COG1937	Protein conserved in bacteria
LO772_15980	COG0671	phosphoesterase, PA-phosphatase related
LO772_16035	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_16050	COG1309	transcriptional regulator
LO772_16065	COG0579	oxidoreductase
LO772_16070	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LO772_16110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LO772_16130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_16145	COG0454	-acetyltransferase
LO772_16145	COG0456	acetyltransferase
LO772_16160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LO772_16165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO772_16170	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO772_16175	COG1120	ATPase activity
LO772_16200	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
LO772_16205	COG1518	maintenance of DNA repeat elements
LO772_16375	COG0791	NLP P60 protein
LO772_16375	COG3883	PFAM NLP P60 protein
LO772_16445	COG4974	Belongs to the 'phage' integrase family
LO772_16470	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LO772_16475	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LO772_16485	COG0513	Belongs to the DEAD box helicase family
LO772_16585	COG2188	Transcriptional regulator
LO772_16660	COG0702	epimerase
LO772_16680	COG0175	sulfate reduction
LO772_16685	COG2895	sulfate adenylyltransferase (ATP) activity
LO772_16685	COG0529	Catalyzes the synthesis of activated sulfate
LO772_16695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_16715	COG1802	Transcriptional regulator
LO772_16720	COG1024	Enoyl-CoA hydratase
LO772_16725	COG3467	pyridoxamine 5'-phosphate
LO772_16745	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_16810	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LO772_16830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LO772_16835	COG0047	phosphoribosylformylglycinamidine synthase activity
LO772_16840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LO772_16860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LO772_16875	COG0151	Belongs to the GarS family
LO772_16900	COG1802	Transcriptional regulator
LO772_16910	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LO772_16925	COG0191	fructose-bisphosphate aldolase activity
LO772_16930	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO772_16935	COG0586	Pfam SNARE associated Golgi protein
LO772_16940	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LO772_16950	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LO772_16970	COG0542	response to heat
LO772_16990	COG0789	Transcriptional regulator
LO772_16995	COG0484	heat shock protein binding
LO772_17000	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LO772_17005	COG0443	Heat shock 70 kDa protein
LO772_17015	COG0247	lactate metabolic process
LO772_17015	COG2181	nitrate reductase activity
LO772_17045	COG4106	trans-aconitate 2-methyltransferase activity
LO772_17145	COG0717	Belongs to the dCTP deaminase family
LO772_17155	COG3842	ATPase activity
LO772_17165	COG1175	transmembrane transport
LO772_17175	COG1234	tRNA 3'-trailer cleavage
LO772_17180	COG0583	DNA-binding transcription factor activity
LO772_17190	COG0189	ligase activity
LO772_17205	COG1959	2 iron, 2 sulfur cluster binding
LO772_17220	COG0300	oxidoreductase activity
LO772_17250	COG1741	Belongs to the pirin family
LO772_17270	COG0837	glucose binding
LO772_17275	COG0800	Aldolase
LO772_17280	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LO772_17310	COG1960	acyl-CoA dehydrogenase activity
LO772_17315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LO772_17325	COG1362	aminopeptidase activity
LO772_17345	COG0508	dehydrogenase complex catalyzes the overall conversion of
LO772_17350	COG0022	dehydrogenase e1 component
LO772_17360	COG4988	ABC transporter
LO772_17365	COG1294	oxidase, subunit
LO772_17370	COG1271	oxidase subunit
LO772_17375	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LO772_17380	COG1609	Transcriptional regulator
LO772_17385	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LO772_17390	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LO772_17400	COG0583	DNA-binding transcription factor activity
LO772_17415	COG2304	oxidoreductase activity
LO772_17435	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
LO772_17470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LO772_17490	COG0653	protein targeting
LO772_17525	COG3852	Histidine kinase
LO772_17555	COG2837	iron assimilation
LO772_17565	COG0077	Prephenate dehydratase
LO772_17570	COG1597	lipid kinase activity
LO772_17575	COG0671	phosphoesterase, PA-phosphatase related
LO772_17580	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LO772_17585	COG0561	phosphatase activity
LO772_17595	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LO772_17600	COG1733	regulation of RNA biosynthetic process
LO772_17605	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_17640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_17660	COG0561	phosphatase activity
LO772_17670	COG0515	serine threonine protein kinase
LO772_17695	COG3321	synthase
LO772_17695	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_17695	COG0604	alcohol dehydrogenase
LO772_17700	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LO772_17710	COG0746	molybdenum cofactor guanylyltransferase activity
LO772_17730	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_17735	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LO772_17735	COG0425	Belongs to the sulfur carrier protein TusA family
LO772_17745	COG1309	transcriptional regulator
LO772_17760	COG1764	response to oxidative stress
LO772_17775	COG1716	ATPase activity
LO772_17780	COG1716	ATPase activity
LO772_17795	COG0768	penicillin binding
LO772_17800	COG0515	serine threonine protein kinase
LO772_17805	COG3764	Sortase (surface protein transpeptidase)
LO772_17810	COG3764	Sortase (surface protein transpeptidase)
LO772_17825	COG3764	Sortase (surface protein transpeptidase)
LO772_17840	COG0705	Rhomboid family
LO772_17880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LO772_17885	COG0187	DNA topoisomerase II activity
LO772_17890	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
LO772_17895	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LO772_17900	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LO772_17905	COG0592	DNA-directed DNA polymerase activity
LO772_17915	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LO772_17925	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LO772_17930	COG0706	membrane insertase activity
LO772_17940	COG0357	Ribosomal RNA small subunit methyltransferase G
LO772_17945	COG1192	Involved in chromosome partitioning
LO772_17955	COG1181	Belongs to the D-alanine--D-alanine ligase family
LO772_17960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO772_17970	COG0860	N-Acetylmuramoyl-L-alanine amidase
LO772_17970	COG3409	Peptidoglycan-binding domain 1 protein
LO772_17975	COG3118	belongs to the thioredoxin family
LO772_17980	COG0492	ferredoxin-NADP+ reductase activity
LO772_17990	COG1595	DNA-templated transcription, initiation
LO772_18015	COG0617	tRNA 3'-terminal CCA addition
LO772_18040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LO772_18075	COG0360	Binds together with S18 to 16S ribosomal RNA
LO772_18085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LO772_18090	COG0359	binds to the 23S rRNA
LO772_18130	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_18135	COG4585	Histidine kinase
LO772_18140	COG2197	response regulator
LO772_18145	COG4585	Histidine kinase
LO772_18150	COG2197	response regulator
LO772_18165	COG0626	cystathionine gamma-synthase activity
LO772_18170	COG1950	PFAM Membrane protein of
LO772_18175	COG0662	Cupin 2, conserved barrel domain protein
LO772_18185	COG2268	Band 7 protein
LO772_18195	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LO772_18235	COG1960	acyl-CoA dehydrogenase activity
LO772_18255	COG0183	Belongs to the thiolase family
LO772_18270	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_18275	COG1309	transcriptional regulator
LO772_18280	COG0745	RESPONSE REGULATOR receiver
LO772_18355	COG2080	2 iron, 2 sulfur cluster binding
LO772_18360	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LO772_18365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LO772_18380	COG2197	response regulator
LO772_18385	COG4585	Histidine kinase
LO772_18410	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_18435	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_18445	COG2409	Drug exporters of the RND superfamily
LO772_18450	COG4585	Histidine kinase
LO772_18455	COG2197	response regulator
LO772_18470	COG0667	Aldo Keto reductase
LO772_18495	COG0183	Belongs to the thiolase family
LO772_18505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO772_18515	COG1366	Belongs to the anti-sigma-factor antagonist family
LO772_18555	COG0420	3'-5' exonuclease activity
LO772_18570	COG0463	Glycosyl transferase, family 2
LO772_18610	COG1191	sigma factor activity
LO772_18620	COG1191	sigma factor activity
LO772_18640	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LO772_18655	COG0590	tRNA wobble adenosine to inosine editing
LO772_18755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_18845	COG0714	Associated with various cellular activities
LO772_18870	COG1335	isochorismatase
LO772_18880	COG0154	amidase activity
LO772_18885	COG0747	negative chemotaxis
LO772_18890	COG4608	Belongs to the ABC transporter superfamily
LO772_18905	COG0601	transmembrane transport
LO772_18940	COG2267	carboxylic ester hydrolase activity
LO772_18955	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LO772_18980	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LO772_18985	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LO772_19005	COG1595	DNA-templated transcription, initiation
LO772_19055	COG0456	acetyltransferase
LO772_19060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LO772_19065	COG1917	Cupin 2, conserved barrel domain protein
LO772_19070	COG5285	phytanoyl-CoA dioxygenase
LO772_19110	COG1011	Hydrolase
LO772_19115	COG2319	Wd-40 repeat
LO772_19115	COG4249	Peptidase C14 caspase catalytic subunit p20
LO772_19130	COG1408	metallophosphoesterase
LO772_19140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LO772_19175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO772_19200	COG0596	Alpha beta hydrolase
LO772_19210	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LO772_19220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO772_19225	COG0288	reversible hydration of carbon dioxide
LO772_19290	COG1366	Belongs to the anti-sigma-factor antagonist family
LO772_19295	COG2172	sigma factor antagonist activity
LO772_19300	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LO772_19315	COG1754	DNA topoisomerase type I activity
LO772_19315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LO772_19320	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LO772_19325	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LO772_19395	COG2154	pterin-4-alpha-carbinolamine dehydratase
LO772_19440	COG0745	RESPONSE REGULATOR receiver
LO772_19445	COG2205	protein histidine kinase activity
LO772_19460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LO772_19470	COG1132	(ABC) transporter
LO772_19485	COG1129	ABC transporter
LO772_19495	COG1172	Belongs to the binding-protein-dependent transport system permease family
LO772_19510	COG4952	isomerase
LO772_19515	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_19515	COG3347	Dehydrogenase
LO772_19520	COG2160	L-arabinose isomerase activity
LO772_19525	COG1070	Carbohydrate kinase
LO772_19535	COG1556	Lactate utilization protein
LO772_19540	COG1139	Iron-sulfur cluster binding protein
LO772_19545	COG0247	lactate metabolic process
LO772_19550	COG2186	Transcriptional regulator
LO772_19585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_19600	COG0586	Pfam SNARE associated Golgi protein
LO772_19615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LO772_19620	COG2027	D-alanyl-D-alanine carboxypeptidase
LO772_19630	COG0037	tRNA processing
LO772_19635	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LO772_19645	COG0302	gtp cyclohydrolase
LO772_19650	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LO772_19660	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LO772_19680	COG0649	NAD binding
LO772_19715	COG2197	response regulator
LO772_19735	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LO772_19745	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LO772_19755	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LO772_19775	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LO772_19790	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LO772_19825	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO772_19830	COG2409	Drug exporters of the RND superfamily
LO772_19845	COG1194	a g-specific adenine glycosylase
LO772_19855	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
LO772_19860	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LO772_19875	COG0248	Ppx GppA phosphatase
LO772_19880	COG1082	Xylose isomerase domain protein TIM barrel
LO772_19885	COG0129	dihydroxy-acid dehydratase activity
LO772_19890	COG0506	proline dehydrogenase activity
LO772_19895	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LO772_19900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LO772_19910	COG0123	including yeast histone deacetylase and acetoin utilization protein
LO772_19960	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LO772_19965	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LO772_19970	COG0181	hydroxymethylbilane synthase activity
LO772_19975	COG1648	precorrin-2 dehydrogenase activity
LO772_19975	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LO772_19980	COG0113	porphobilinogen synthase activity
LO772_20005	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_20020	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_20025	COG1960	acyl-CoA dehydrogenase activity
LO772_20030	COG1960	acyl-CoA dehydrogenase activity
LO772_20050	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_20055	COG3386	PFAM SMP-30 Gluconolaconase
LO772_20060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LO772_20065	COG0800	Aldolase
LO772_20070	COG4948	Mandelate Racemase Muconate Lactonizing
LO772_20075	COG2186	Transcriptional regulator
LO772_20085	COG1063	alcohol dehydrogenase
LO772_20090	COG1172	Belongs to the binding-protein-dependent transport system permease family
LO772_20095	COG1129	ABC transporter
LO772_20100	COG1879	ABC-type sugar transport system periplasmic component
LO772_20115	COG1960	acyl-CoA dehydrogenase activity
LO772_20135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_20140	COG1960	acyl-CoA dehydrogenase activity
LO772_20150	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_20155	COG1960	acyl-CoA dehydrogenase activity
LO772_20160	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_20175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO772_20180	COG1024	Enoyl-CoA hydratase
LO772_20195	COG1960	acyl-CoA dehydrogenase activity
LO772_20210	COG1309	transcriptional regulator
LO772_20215	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_20220	COG1024	Enoyl-CoA hydratase
LO772_20280	COG0183	Belongs to the thiolase family
LO772_20285	COG1960	acyl-CoA dehydrogenase activity
LO772_20305	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LO772_20310	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_20325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_20335	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
LO772_20345	COG0110	maltose O-acetyltransferase activity
LO772_20350	COG1960	acyl-CoA dehydrogenase activity
LO772_20355	COG1960	acyl-CoA dehydrogenase activity
LO772_20360	COG1063	alcohol dehydrogenase
LO772_20370	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_20380	COG0596	Alpha beta hydrolase
LO772_20405	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LO772_20415	COG0183	Belongs to the thiolase family
LO772_20425	COG2070	2-Nitropropane dioxygenase
LO772_20445	COG0477	Major facilitator Superfamily
LO772_20455	COG2124	cytochrome p450
LO772_20495	COG1970	mechanosensitive ion channel activity
LO772_20505	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LO772_20515	COG3263	regulation of cellular component size
LO772_20525	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LO772_20530	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LO772_20545	COG0521	Mo-molybdopterin cofactor biosynthetic process
LO772_20585	COG0084	hydrolase, TatD family'
LO772_20595	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LO772_20600	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LO772_20605	COG0488	(ABC) transporter
LO772_20610	COG1086	Polysaccharide biosynthesis protein
LO772_20620	COG0148	phosphopyruvate hydratase activity
LO772_20640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO772_20640	COG2146	nitrite reductase [NAD(P)H] activity
LO772_20645	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LO772_20670	COG0183	Belongs to the thiolase family
LO772_20675	COG2755	lipolytic protein G-D-S-L family
LO772_20700	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_20715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LO772_20755	COG2188	Transcriptional regulator
LO772_20775	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LO772_20795	COG1846	Transcriptional regulator
LO772_20800	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LO772_20815	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LO772_20825	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LO772_20835	COG1331	Highly conserved protein containing a thioredoxin domain
LO772_20840	COG5650	phosphatidylinositol metabolic process
LO772_20850	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LO772_20855	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LO772_20860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LO772_20870	COG0183	Belongs to the thiolase family
LO772_20880	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LO772_20885	COG0450	alkyl hydroperoxide reductase
LO772_20900	COG0114	fumarate hydratase activity
LO772_20905	COG1556	Lactate utilization protein
LO772_20910	COG1139	Iron-sulfur cluster binding protein
LO772_20915	COG0247	lactate metabolic process
LO772_20920	COG1131	(ABC) transporter
LO772_20935	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LO772_20935	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LO772_20940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO772_20995	COG1722	exodeoxyribonuclease VII activity
LO772_21005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LO772_21015	COG0640	Transcriptional regulator
LO772_21025	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_21075	COG1570	exodeoxyribonuclease VII activity
LO772_21080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LO772_21095	COG0012	GTP binding
LO772_21130	COG2154	pterin-4-alpha-carbinolamine dehydratase
LO772_21135	COG0494	nUDIX hydrolase
LO772_21150	COG1053	succinate dehydrogenase
LO772_21170	COG1217	gtp-binding protein TYPA
LO772_21180	COG4166	transmembrane transport
LO772_21190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO772_21200	COG4608	Belongs to the ABC transporter superfamily
LO772_21205	COG0747	negative chemotaxis
LO772_21210	COG0601	transmembrane transport
LO772_21215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO772_21225	COG4608	Belongs to the ABC transporter superfamily
LO772_21240	COG2226	methyltransferase
LO772_21245	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
LO772_21265	COG2226	methyltransferase
LO772_21270	COG3979	chitinase
LO772_21305	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LO772_21310	COG1611	Belongs to the LOG family
LO772_21330	COG0519	Catalyzes the synthesis of GMP from XMP
LO772_21335	COG1024	Enoyl-CoA hydratase
LO772_21350	COG1595	DNA-templated transcription, initiation
LO772_21360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LO772_21365	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LO772_21385	COG2239	Acts as a magnesium transporter
LO772_21405	COG2301	Belongs to the HpcH HpaI aldolase family
LO772_21460	COG0745	RESPONSE REGULATOR receiver
LO772_21465	COG2205	protein histidine kinase activity
LO772_21495	COG1832	CoA-binding protein
LO772_21500	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
LO772_21505	COG1960	acyl-CoA dehydrogenase activity
LO772_21540	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_21545	COG1316	TRANSCRIPTIONal
LO772_21550	COG1316	TRANSCRIPTIONal
LO772_21585	COG0297	glycogen (starch) synthase activity
LO772_21615	COG0673	inositol 2-dehydrogenase activity
LO772_21665	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
LO772_21665	COG0778	Nitroreductase
LO772_21670	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LO772_21715	COG2835	tetraacyldisaccharide 4'-kinase activity
LO772_21725	COG1482	cell wall glycoprotein biosynthetic process
LO772_21735	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LO772_21795	COG0714	Associated with various cellular activities
LO772_21815	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LO772_21820	COG0745	RESPONSE REGULATOR receiver
LO772_21825	COG5002	protein histidine kinase activity
LO772_21830	COG0823	Involved in the tonB-independent uptake of proteins
LO772_21835	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LO772_21845	COG3214	Protein conserved in bacteria
LO772_21855	COG0653	protein targeting
LO772_21875	COG1012	belongs to the aldehyde dehydrogenase family
LO772_21890	COG1674	ftsk spoiiie
LO772_21895	COG0515	serine threonine protein kinase
LO772_21895	COG0515	serine threonine protein kinase
LO772_21900	COG0515	serine threonine protein kinase
LO772_21905	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
LO772_21920	COG2884	Cell division ATP-binding protein ftsE
LO772_21925	COG2177	Part of the ABC transporter FtsEX involved in
LO772_21930	COG0739	heme binding
LO772_21935	COG0793	Belongs to the peptidase S41A family
LO772_21940	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LO772_21960	COG0776	regulation of translation
LO772_21965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LO772_21970	COG1678	Uncharacterized ACR, COG1678
LO772_21990	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LO772_22005	COG3480	Lon protease (S16) C-terminal proteolytic domain
LO772_22010	COG1522	sequence-specific DNA binding
LO772_22015	COG3185	4-Hydroxyphenylpyruvate dioxygenase
LO772_22030	COG1335	isochorismatase
LO772_22040	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LO772_22065	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LO772_22070	COG1234	tRNA 3'-trailer cleavage
LO772_22075	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LO772_22085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LO772_22090	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LO772_22120	COG1122	ATPase activity
LO772_22130	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LO772_22150	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_22155	COG1132	(ABC) transporter
LO772_22160	COG1132	(ABC) transporter
LO772_22200	COG0508	dehydrogenase complex catalyzes the overall conversion of
LO772_22200	COG0567	Dehydrogenase, E1 component
LO772_22205	COG2205	protein histidine kinase activity
LO772_22210	COG0745	RESPONSE REGULATOR receiver
LO772_22240	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LO772_22255	COG1799	cell septum assembly
LO772_22270	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LO772_22275	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_22300	COG1515	deoxyribonuclease V activity
LO772_22305	COG0577	efflux transmembrane transporter activity
LO772_22310	COG0577	efflux transmembrane transporter activity
LO772_22310	COG1136	(ABC) transporter
LO772_22315	COG0577	efflux transmembrane transporter activity
LO772_22315	COG1136	(ABC) transporter
LO772_22325	COG3226	Transcriptional regulator
LO772_22355	COG1595	DNA-templated transcription, initiation
LO772_22365	COG0702	epimerase
LO772_22440	COG0714	Associated with various cellular activities
LO772_22465	COG0739	heme binding
LO772_22465	COG1196	nuclear chromosome segregation
LO772_22465	COG0741	lytic transglycosylase activity
LO772_22520	COG3284	Transcriptional regulator
LO772_22525	COG2207	Transcriptional regulator
LO772_22555	COG2124	cytochrome p450
LO772_22625	COG1473	amidohydrolase
LO772_22625	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LO772_22715	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LO772_22730	COG0515	serine threonine protein kinase
LO772_22790	COG1316	TRANSCRIPTIONal
LO772_22840	COG4585	Histidine kinase
LO772_22845	COG2197	response regulator
LO772_22865	COG0673	inositol 2-dehydrogenase activity
LO772_22870	COG1160	GTP binding
LO772_22880	COG0629	single-stranded DNA binding
LO772_22885	COG3415	Transposase
LO772_22885	COG2801	Transposase and inactivated derivatives
LO772_22915	COG2409	Drug exporters of the RND superfamily
LO772_22920	COG0366	Alpha amylase catalytic
LO772_22925	COG2346	COG2346, Truncated hemoglobins
LO772_22930	COG0668	transmembrane transport
LO772_22935	COG1505	serine-type exopeptidase activity
LO772_22965	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LO772_22975	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LO772_22980	COG1268	BioY protein
LO772_23005	COG0386	Belongs to the glutathione peroxidase family
LO772_23030	COG0544	peptidyl-prolyl cis-trans isomerase activity
LO772_23035	COG0740	serine-type endopeptidase activity
LO772_23040	COG0740	serine-type endopeptidase activity
LO772_23045	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LO772_23055	COG0525	valine-tRNA ligase activity
LO772_23060	COG0285	dihydrofolate synthase activity
LO772_23070	COG0105	UTP biosynthetic process
LO772_23075	COG1077	Cell shape determining protein MreB Mrl
LO772_23090	COG0768	penicillin binding
LO772_23095	COG0772	Belongs to the SEDS family
LO772_23105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LO772_23110	COG0438	transferase activity, transferring glycosyl groups
LO772_23115	COG0110	maltose O-acetyltransferase activity
LO772_23120	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LO772_23180	COG0535	radical SAM domain protein
LO772_23215	COG1530	ribonuclease E activity
LO772_23220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LO772_23225	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LO772_23230	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LO772_23235	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LO772_23245	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LO772_23280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LO772_23290	COG0799	negative regulation of ribosome biogenesis
LO772_23320	COG1012	belongs to the aldehyde dehydrogenase family
LO772_23330	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LO772_23340	COG0495	leucyl-tRNA aminoacylation
LO772_23350	COG1307	EDD domain protein, DegV family
LO772_23355	COG1596	polysaccharide export
LO772_23355	COG1555	photosystem II stabilization
LO772_23370	COG0268	Binds directly to 16S ribosomal RNA
LO772_23380	COG0481	GTPase activity
LO772_23410	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
LO772_23435	COG3119	arylsulfatase activity
LO772_23435	COG3408	Glycogen debranching enzyme
LO772_23455	COG0601	transmembrane transport
LO772_23460	COG0747	negative chemotaxis
LO772_23475	COG1420	regulation of RNA biosynthetic process
LO772_23480	COG0484	heat shock protein binding
LO772_23490	COG0537	adenosine 5'-monophosphoramidase activity
LO772_23495	COG1234	tRNA 3'-trailer cleavage
LO772_23505	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LO772_23525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LO772_23530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LO772_23540	COG1381	Involved in DNA repair and RecF pathway recombination
LO772_23545	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LO772_23550	COG0701	Predicted permease
LO772_23565	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LO772_23570	COG1120	ATPase activity
LO772_23575	COG0803	Belongs to the bacterial solute-binding protein 9 family
LO772_23575	COG3443	Belongs to the bacterial solute-binding protein 9 family
LO772_23580	COG0423	glycine-tRNA ligase activity
LO772_23595	COG0574	Belongs to the PEP-utilizing enzyme family
LO772_23595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LO772_23610	COG0052	Belongs to the universal ribosomal protein uS2 family
LO772_23615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LO772_23620	COG0528	UMP kinase activity
LO772_23625	COG0233	cytoplasmic translational termination
LO772_23630	COG0575	Belongs to the CDS family
LO772_23635	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LO772_23645	COG1012	belongs to the aldehyde dehydrogenase family
LO772_23710	COG0750	zinc metalloprotease
LO772_23715	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LO772_23720	COG0596	Alpha beta hydrolase
LO772_23740	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
LO772_23755	COG0779	Required for maturation of 30S ribosomal subunits
LO772_23770	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LO772_23780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LO772_23785	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LO772_23790	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LO772_23830	COG1404	Belongs to the peptidase S8 family
LO772_23835	COG1674	ftsk spoiiie
LO772_23845	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LO772_23850	COG1185	polyribonucleotide nucleotidyltransferase activity
LO772_23855	COG0612	Peptidase, M16
LO772_23860	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LO772_23880	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
LO772_23885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO772_23890	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
LO772_23900	COG2770	Histidine kinase
LO772_23900	COG2208	phosphoserine phosphatase activity
LO772_23905	COG2205	protein histidine kinase activity
LO772_23905	COG3437	response regulator, receiver
LO772_23905	COG3850	Histidine kinase
LO772_23905	COG4999	Histidine kinase
LO772_23915	COG1674	ftsk spoiiie
LO772_23925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LO772_23935	COG1058	Belongs to the CinA family
LO772_23935	COG1546	Belongs to the CinA family
LO772_23940	COG1396	sequence-specific DNA binding
LO772_23945	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_23955	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LO772_23960	COG1201	RNA secondary structure unwinding
LO772_23970	COG1994	Peptidase M50
LO772_23975	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LO772_23980	COG0477	Major facilitator Superfamily
LO772_23985	COG1309	transcriptional regulator
LO772_24000	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LO772_24000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LO772_24005	COG1595	DNA-templated transcription, initiation
LO772_24010	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LO772_24025	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LO772_24065	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LO772_24070	COG0321	lipoyl(octanoyl) transferase activity
LO772_24095	COG0508	dehydrogenase complex catalyzes the overall conversion of
LO772_24100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LO772_24110	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LO772_24115	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
LO772_24120	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LO772_24135	COG0667	Aldo Keto reductase
LO772_24160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LO772_24175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LO772_24185	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LO772_24190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LO772_24205	COG1376	ErfK ybiS ycfS ynhG family protein
LO772_24210	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LO772_24215	COG0723	plastoquinol--plastocyanin reductase activity
LO772_24220	COG2010	Cytochrome c
LO772_24225	COG1845	cytochrome c oxidase, subunit III
LO772_24240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LO772_24245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LO772_24280	COG0501	Belongs to the peptidase M48B family
LO772_24290	COG0438	transferase activity, transferring glycosyl groups
LO772_24310	COG0003	Pfam Anion-transporting ATPase
LO772_24320	COG1940	carbohydrate kinase activity
LO772_24340	COG4585	Histidine kinase
LO772_24350	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LO772_24355	COG0205	6-phosphofructokinase activity
LO772_24365	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LO772_24385	COG2193	ferroxidase activity
LO772_24390	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LO772_24395	COG0515	serine threonine protein kinase
LO772_24395	COG2815	serine threonine protein kinase
LO772_24400	COG2022	thiamine diphosphate biosynthetic process
LO772_24410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LO772_24410	COG2022	thiamine diphosphate biosynthetic process
LO772_24425	COG0352	thiamine-phosphate diphosphorylase activity
LO772_24435	COG0142	geranyltranstransferase activity
LO772_24450	COG0584	glycerophosphoryl diester phosphodiesterase
LO772_24475	COG2186	Transcriptional regulator
LO772_24575	COG0587	DNA-directed DNA polymerase activity
LO772_24580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LO772_24585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LO772_24610	COG0714	Associated with various cellular activities
LO772_24620	COG2001	Belongs to the MraZ family
LO772_24625	COG0275	rRNA processing
LO772_24635	COG0768	penicillin binding
LO772_24640	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LO772_24650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LO772_24655	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LO772_24665	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LO772_24675	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LO772_24690	COG1799	cell septum assembly
LO772_24700	COG3599	regulation of cell shape
LO772_24705	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LO772_24750	COG0587	DNA-directed DNA polymerase activity
LO772_24790	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LO772_24800	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LO772_24805	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LO772_24810	COG0131	Imidazoleglycerol-phosphate dehydratase
LO772_24815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LO772_24820	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LO772_24825	COG0251	oxidation-reduction process
LO772_24830	COG0107	imidazoleglycerol-phosphate synthase activity
LO772_24835	COG1968	undecaprenyl-diphosphatase activity
LO772_24845	COG1132	(ABC) transporter
LO772_24850	COG1132	(ABC) transporter
LO772_24870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LO772_24875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LO772_24900	COG0134	indole-3-glycerol-phosphate synthase activity
LO772_24905	COG0133	tryptophan synthase activity
LO772_24910	COG0159	tryptophan synthase activity
LO772_24925	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LO772_24935	COG0067	glutamate synthase
LO772_24935	COG0069	glutamate synthase activity
LO772_24935	COG0070	glutamate synthase
LO772_24990	COG2226	methyltransferase
LO772_24995	COG0539	negative regulation of cytoplasmic translation
LO772_25010	COG0671	phosphoesterase, PA-phosphatase related
LO772_25015	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LO772_25020	COG0277	FAD linked oxidase domain protein
LO772_25030	COG0237	dephospho-CoA kinase activity
LO772_25040	COG0556	nucleotide-excision repair
LO772_25055	COG1199	ATP-dependent helicase activity
LO772_25055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO772_25075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LO772_25085	COG0322	excinuclease ABC activity
LO772_25090	COG1660	Displays ATPase and GTPase activities
LO772_25100	COG1481	regulation of sporulation
LO772_25105	COG4552	Acetyltransferase involved in intracellular survival and related
LO772_25115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LO772_25120	COG0126	phosphoglycerate kinase activity
LO772_25125	COG0149	triose-phosphate isomerase activity
LO772_25130	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LO772_25155	COG0702	epimerase
LO772_25160	COG1595	DNA-templated transcription, initiation
LO772_25165	COG2151	metal-sulfur cluster biosynthetic enzyme
LO772_25170	COG0822	iron-sulfur transferase activity
LO772_25175	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LO772_25180	COG0396	ATPase activity
LO772_25190	COG0719	Fe-S assembly protein
LO772_25215	COG1131	(ABC) transporter
LO772_25235	COG0109	protoheme IX farnesyltransferase activity
LO772_25245	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LO772_25265	COG0363	glucosamine-6-phosphate deaminase activity
LO772_25290	COG0488	(ABC) transporter
LO772_25300	COG1024	Enoyl-CoA hydratase
LO772_25310	COG1302	Protein conserved in bacteria
LO772_25340	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_25350	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LO772_25355	COG3346	SURF1 family
LO772_25385	COG0300	oxidoreductase activity
LO772_25465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LO772_25480	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
LO772_25495	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_25500	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LO772_25510	COG2409	Drug exporters of the RND superfamily
LO772_25520	COG0560	Phosphoserine phosphatase
LO772_25520	COG3830	Belongs to the UPF0237 family
LO772_25530	COG1716	ATPase activity
LO772_25530	COG1131	(ABC) transporter
LO772_25530	COG0842	Transport permease protein
LO772_25540	COG2018	Roadblock/LC7 domain
LO772_25555	COG1129	ABC transporter
LO772_25570	COG1119	ATPase activity
LO772_25590	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LO772_25595	COG1492	cobalamin metabolic process
LO772_25610	COG2409	Drug exporters of the RND superfamily
LO772_25645	COG2094	Belongs to the DNA glycosylase MPG family
LO772_25650	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LO772_25690	COG0647	UMP catabolic process
LO772_25715	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LO772_25720	COG0497	DNA recombination
LO772_25745	COG0438	transferase activity, transferring glycosyl groups
LO772_25750	COG3387	PFAM Glycoside hydrolase 15-related
LO772_25755	COG0504	CTP synthase activity
LO772_25760	COG0494	nUDIX hydrolase
LO772_25765	COG1309	transcriptional regulator
LO772_25770	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_25775	COG3629	intracellular signal transduction
LO772_25775	COG3903	Transcriptional regulator
LO772_25780	COG0686	Belongs to the AlaDH PNT family
LO772_25795	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LO772_25805	COG1187	pseudouridine synthase activity
LO772_25830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LO772_25840	COG1160	GTP binding
LO772_25900	COG1960	acyl-CoA dehydrogenase activity
LO772_25910	COG1960	acyl-CoA dehydrogenase activity
LO772_25915	COG1960	acyl-CoA dehydrogenase activity
LO772_25920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LO772_25935	COG2733	membrane
LO772_25970	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LO772_25970	COG0515	serine threonine protein kinase
LO772_25990	COG2171	N-acyltransferase activity
LO772_26025	COG1605	Chorismate mutase
LO772_26025	COG0287	Prephenate dehydrogenase
LO772_26030	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LO772_26045	COG1024	Enoyl-CoA hydratase
LO772_26050	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LO772_26100	COG1366	Belongs to the anti-sigma-factor antagonist family
LO772_26115	COG1946	Acyl-CoA thioesterase
LO772_26130	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LO772_26130	COG0515	serine threonine protein kinase
LO772_26180	COG0612	Peptidase, M16
LO772_26195	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LO772_26210	COG2197	response regulator
LO772_26225	COG0688	phosphatidylethanolamine metabolic process
LO772_26255	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LO772_26260	COG0121	glutamine amidotransferase
LO772_26265	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LO772_26270	COG3572	ergothioneine biosynthetic process
LO772_26285	COG2205	protein histidine kinase activity
LO772_26315	COG2124	cytochrome p450
LO772_26335	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LO772_26395	COG2183	response to ionizing radiation
LO772_26405	COG0714	Associated with various cellular activities
LO772_26420	COG2813	Specifically methylates the guanine in position
LO772_26425	COG1674	ftsk spoiiie
LO772_26460	COG3012	SEC-C Motif Domain Protein
LO772_26465	COG0488	(ABC) transporter
LO772_26475	COG4585	Histidine kinase
LO772_26480	COG2197	response regulator
LO772_26505	COG0137	argininosuccinate synthase activity
LO772_26555	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LO772_26580	COG2197	response regulator
LO772_26585	COG4585	Histidine kinase
LO772_26595	COG0577	efflux transmembrane transporter activity
LO772_26595	COG1136	(ABC) transporter
LO772_26635	COG1131	(ABC) transporter
LO772_26645	COG2197	response regulator
LO772_26650	COG4221	oxidoreductase activity
LO772_26655	COG1309	transcriptional regulator
LO772_26670	COG1408	metallophosphoesterase
LO772_26675	COG2315	Protein conserved in bacteria
LO772_26680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO772_26695	COG0584	glycerophosphoryl diester phosphodiesterase
LO772_26700	COG2181	nitrate reductase activity
LO772_26700	COG0247	lactate metabolic process
LO772_26705	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LO772_26710	COG2086	electron transfer activity
LO772_26725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_26745	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_26765	COG0673	inositol 2-dehydrogenase activity
LO772_26780	COG4638	Rieske (2fe-2S)
LO772_26785	COG0583	DNA-binding transcription factor activity
LO772_26795	COG1309	transcriptional regulator
LO772_26800	COG1595	DNA-templated transcription, initiation
LO772_26830	COG3250	beta-galactosidase activity
LO772_26835	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LO772_26835	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LO772_26855	COG4585	Histidine kinase
LO772_26865	COG4221	oxidoreductase activity
LO772_26935	COG3250	beta-galactosidase activity
LO772_26970	COG2226	methyltransferase
LO772_26975	COG0640	Transcriptional regulator
LO772_26985	COG0640	Transcriptional regulator
LO772_27015	COG2072	flavoprotein involved in K transport
LO772_27020	COG1742	UPF0060 membrane protein
LO772_27040	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LO772_27055	COG0798	PFAM Bile acid sodium symporter
LO772_27060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LO772_27065	COG0492	ferredoxin-NADP+ reductase activity
LO772_27070	COG2226	methyltransferase
LO772_27090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LO772_27095	COG0581	inorganic phosphate transmembrane transporter activity
LO772_27100	COG0573	inorganic phosphate transmembrane transporter activity
LO772_27105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LO772_27125	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_27150	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LO772_27155	COG0483	inositol monophosphate 1-phosphatase activity
LO772_27185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LO772_27200	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LO772_27210	COG0602	queuosine metabolic process
LO772_27225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LO772_27385	COG1388	LysM domain
LO772_27385	COG0791	NLP P60 protein
LO772_27385	COG3103	Sh3 type 3 domain protein
LO772_27465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LO772_27495	COG0667	Aldo Keto reductase
LO772_27500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_27510	COG0598	Magnesium transport protein CorA
LO772_27540	COG0215	cysteine-tRNA ligase activity
LO772_27570	COG0438	transferase activity, transferring glycosyl groups
LO772_27575	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
LO772_27585	COG0438	transferase activity, transferring glycosyl groups
LO772_27610	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LO772_27620	COG0500	methyltransferase
LO772_27665	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LO772_27685	COG0726	polysaccharide deacetylase
LO772_27700	COG0438	transferase activity, transferring glycosyl groups
LO772_27705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LO772_27760	COG1024	Enoyl-CoA hydratase
LO772_27785	COG1278	Cold shock
LO772_27800	COG2910	NAD(P)H-binding
LO772_27820	COG1077	Cell shape determining protein MreB Mrl
LO772_27835	COG0183	Belongs to the thiolase family
LO772_27845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_27855	COG4865	methylaspartate mutase activity
LO772_28015	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LO772_28045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LO772_28050	COG1560	Kdo2-lipid A biosynthetic process
LO772_28055	COG0438	transferase activity, transferring glycosyl groups
LO772_28065	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
LO772_28070	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
LO772_28075	COG0217	transcriptional regulatory protein
LO772_28090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LO772_28095	COG0632	four-way junction helicase activity
LO772_28100	COG2255	four-way junction helicase activity
LO772_28110	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LO772_28115	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LO772_28120	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LO772_28125	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LO772_28130	COG1196	nuclear chromosome segregation
LO772_28135	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LO772_28140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO772_28145	COG0124	histidyl-tRNA synthetase
LO772_28150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LO772_28175	COG0765	amino acid transport
LO772_28180	COG0765	amino acid transport
LO772_28185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LO772_28190	COG1126	abc transporter atp-binding protein
LO772_28195	COG0300	oxidoreductase activity
LO772_28205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LO772_28210	COG0492	ferredoxin-NADP+ reductase activity
LO772_28220	COG0646	methionine synthase
LO772_28220	COG1410	methionine synthase
LO772_28235	COG4585	Histidine kinase
LO772_28240	COG2197	response regulator
LO772_28250	COG0517	IMP dehydrogenase activity
LO772_28250	COG1994	Peptidase M50
LO772_28270	COG1222	aaa ATPase
LO772_28275	COG4122	O-methyltransferase activity
LO772_28290	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LO772_28295	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LO772_28300	COG1609	Transcriptional regulator
LO772_28310	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
LO772_28315	COG0545	Peptidyl-prolyl cis-trans isomerase
LO772_28355	COG0805	protein transport
LO772_28370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LO772_28395	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LO772_28400	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LO772_28405	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LO772_28410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LO772_28415	COG5002	protein histidine kinase activity
LO772_28420	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LO772_28425	COG0072	phenylalanine-tRNA ligase activity
LO772_28425	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO772_28430	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_28435	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LO772_28440	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LO772_28445	COG2838	Isocitrate dehydrogenase
LO772_28450	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LO772_28455	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LO772_28460	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LO772_28465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LO772_28470	COG1438	arginine binding
LO772_28475	COG0165	Argininosuccinate lyase
LO772_28490	COG2011	ABC-type metal ion transport system permease component
LO772_28495	COG1464	Belongs to the NlpA lipoprotein family
LO772_28520	COG1797	cobyrinic acid a,c-diamide synthase activity
LO772_28540	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LO772_28545	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LO772_28545	COG1648	precorrin-2 dehydrogenase activity
LO772_28565	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LO772_28630	COG0076	glutamate decarboxylase activity
LO772_28655	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO772_28660	COG1051	belongs to the nudix hydrolase family
LO772_28665	COG1051	belongs to the nudix hydrolase family
LO772_28675	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LO772_28725	COG2949	membrane
LO772_28730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LO772_28755	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LO772_28755	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LO772_28770	COG0726	polysaccharide deacetylase
LO772_28790	COG0384	phenazine biosynthesis protein PhzF
LO772_28800	COG0436	Aminotransferase
LO772_28815	COG1695	Transcriptional regulator
LO772_28865	COG2329	Antibiotic biosynthesis monooxygenase
LO772_28870	COG0662	Cupin 2, conserved barrel domain protein
LO772_28880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LO772_28885	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LO772_28890	COG2867	negative regulation of translational initiation
LO772_28900	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LO772_28900	COG0825	malonyl-CoA metabolic process
LO772_28905	COG0511	ligase activity, forming carbon-carbon bonds
LO772_28910	COG0439	Biotin carboxylase
LO772_28920	COG1077	Cell shape determining protein MreB Mrl
LO772_28930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LO772_28940	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
LO772_28940	COG2308	Evidence 4 Homologs of previously reported genes of
LO772_28950	COG1966	Carbon starvation protein
LO772_28960	COG0649	NAD binding
LO772_28965	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LO772_28965	COG1796	DNA polymerase
LO772_28975	COG2124	cytochrome p450
LO772_29010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO772_29015	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO772_29020	COG1120	ATPase activity
LO772_29025	COG1169	isochorismate synthase
LO772_29030	COG3486	L-lysine 6-monooxygenase (NADPH) activity
LO772_29035	COG0477	Major facilitator Superfamily
LO772_29045	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LO772_29055	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO772_29080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_29085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_29090	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LO772_29090	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO772_29095	COG1021	2,3-dihydroxybenzoate-AMP ligase
LO772_29105	COG1116	anion transmembrane transporter activity
LO772_29110	COG1695	Transcriptional regulator
LO772_29130	COG1609	Transcriptional regulator
LO772_29140	COG1846	Transcriptional regulator
LO772_29145	COG0477	Major facilitator Superfamily
LO772_29180	COG1609	Transcriptional regulator
LO772_29190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LO772_29195	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LO772_29205	COG3386	PFAM SMP-30 Gluconolaconase
LO772_29210	COG1414	Transcriptional regulator
LO772_29225	COG4948	Mandelate Racemase Muconate Lactonizing
LO772_29240	COG0477	Major facilitator Superfamily
LO772_29245	COG1609	Transcriptional regulator
LO772_29250	COG3250	beta-galactosidase activity
LO772_29255	COG1606	tRNA processing
LO772_29260	COG1691	(AIR) carboxylase
LO772_29265	COG2267	carboxylic ester hydrolase activity
LO772_29285	COG0542	response to heat
LO772_29305	COG1643	Atp-dependent helicase
LO772_29350	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LO772_29350	COG5479	isomerase activity
LO772_29360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LO772_29390	COG2076	Multidrug Resistance protein
LO772_29400	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_29420	COG4264	IucA IucC family
LO772_29520	COG1857	crispr-associated protein
LO772_29535	COG1518	maintenance of DNA repeat elements
LO772_29540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO772_29635	COG4974	Belongs to the 'phage' integrase family
LO772_29800	COG0302	gtp cyclohydrolase
LO772_29915	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_29940	COG0175	sulfate reduction
LO772_29950	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_29960	COG0346	lactoylglutathione lyase activity
LO772_30005	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_30080	COG1960	acyl-CoA dehydrogenase activity
LO772_30090	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_30095	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_30115	COG3250	beta-galactosidase activity
LO772_30120	COG3507	Belongs to the glycosyl hydrolase 43 family
LO772_30130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LO772_30140	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LO772_30235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LO772_30240	COG1121	(ABC) transporter
LO772_30250	COG0803	Belongs to the bacterial solute-binding protein 9 family
LO772_30250	COG0803	Belongs to the bacterial solute-binding protein 9 family
LO772_30255	COG0735	belongs to the Fur family
LO772_30270	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LO772_30275	COG0523	cobalamin synthesis protein
LO772_30280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LO772_30285	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LO772_30505	COG2072	flavoprotein involved in K transport
LO772_30510	COG2124	cytochrome p450
LO772_30540	COG2130	NADP-dependent
LO772_30560	COG2301	Belongs to the HpcH HpaI aldolase family
LO772_30565	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LO772_30570	COG1960	acyl-CoA dehydrogenase activity
LO772_30575	COG1960	acyl-CoA dehydrogenase activity
LO772_30580	COG2124	cytochrome p450
LO772_30585	COG1012	belongs to the aldehyde dehydrogenase family
LO772_30595	COG1024	Enoyl-CoA hydratase
LO772_30605	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_30620	COG1024	Enoyl-CoA hydratase
LO772_30685	COG1024	Enoyl-CoA hydratase
LO772_30695	COG2072	flavoprotein involved in K transport
LO772_30715	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_30720	COG1012	belongs to the aldehyde dehydrogenase family
LO772_30730	COG0667	Aldo Keto reductase
LO772_30735	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LO772_30755	COG0596	Alpha beta hydrolase
LO772_30770	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_30795	COG0493	'glutamate synthase
LO772_30795	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LO772_30820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LO772_30910	COG0673	inositol 2-dehydrogenase activity
LO772_30920	COG0444	Belongs to the ABC transporter superfamily
LO772_30940	COG1082	Xylose isomerase domain protein TIM barrel
LO772_30950	COG1609	Transcriptional regulator
LO772_30960	COG0673	inositol 2-dehydrogenase activity
LO772_30970	COG1929	Belongs to the glycerate kinase type-1 family
LO772_30980	COG1024	Enoyl-CoA hydratase
LO772_30985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_31005	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_31015	COG1024	Enoyl-CoA hydratase
LO772_31035	COG1012	belongs to the aldehyde dehydrogenase family
LO772_31040	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
LO772_31050	COG2124	cytochrome p450
LO772_31100	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_31125	COG1960	acyl-CoA dehydrogenase activity
LO772_31135	COG1024	Enoyl-CoA hydratase
LO772_31150	COG1960	acyl-CoA dehydrogenase activity
LO772_31170	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_31175	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
LO772_31195	COG0183	Belongs to the thiolase family
LO772_31205	COG1960	acyl-CoA dehydrogenase activity
LO772_31215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LO772_31220	COG0183	Belongs to the thiolase family
LO772_31225	COG1024	Enoyl-CoA hydratase
LO772_31230	COG0477	Major facilitator Superfamily
LO772_31235	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_31255	COG1024	Enoyl-CoA hydratase
LO772_31260	COG1960	acyl-CoA dehydrogenase activity
LO772_31265	COG1960	acyl-CoA dehydrogenase activity
LO772_31270	COG2188	Transcriptional regulator
LO772_31290	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_31315	COG1960	acyl-CoA dehydrogenase activity
LO772_31320	COG1960	acyl-CoA dehydrogenase activity
LO772_31330	COG0183	Belongs to the thiolase family
LO772_31345	COG1946	Acyl-CoA thioesterase
LO772_31350	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_31360	COG1960	acyl-CoA dehydrogenase activity
LO772_31365	COG0300	oxidoreductase activity
LO772_31370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LO772_31375	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_31380	COG1960	acyl-CoA dehydrogenase activity
LO772_31400	COG1024	Enoyl-CoA hydratase
LO772_31405	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_31410	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_31415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_31430	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_31435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_31445	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_31450	COG1960	acyl-CoA dehydrogenase activity
LO772_31455	COG0515	serine threonine protein kinase
LO772_31455	COG2815	serine threonine protein kinase
LO772_31465	COG2815	serine threonine protein kinase
LO772_31465	COG0515	serine threonine protein kinase
LO772_31470	COG0515	serine threonine protein kinase
LO772_31600	COG1982	Orn Lys Arg decarboxylase major
LO772_31620	COG1335	isochorismatase
LO772_31640	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LO772_31650	COG2030	dehydratase
LO772_31670	COG0318	PFAM AMP-dependent synthetase and ligase
LO772_31680	COG2207	Transcriptional regulator
LO772_31715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LO772_31765	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO772_31790	COG0445	tRNA wobble uridine modification
LO772_31795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LO772_31805	COG3408	Glycogen debranching enzyme
LO772_31805	COG3119	arylsulfatase activity
LO772_31830	COG0515	serine threonine protein kinase
LO772_31830	COG2815	serine threonine protein kinase
LO772_31850	COG1278	Cold shock
LO772_31885	COG1476	TRANSCRIPTIONal
LO772_31915	COG1349	DNA-binding transcription factor activity
LO772_31920	COG0531	amino acid
LO772_31925	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LO772_31970	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_31980	COG1595	DNA-templated transcription, initiation
LO772_32000	COG3250	beta-galactosidase activity
LO772_32005	COG1309	transcriptional regulator
LO772_32010	COG0546	phosphoglycolate phosphatase activity
LO772_32020	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_32040	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO772_32070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO772_32165	COG1595	DNA-templated transcription, initiation
LO772_32180	COG1120	ATPase activity
LO772_32185	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO772_32190	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO772_32195	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LO772_32200	COG1132	(ABC) transporter
LO772_32200	COG2375	cellular response to nickel ion
LO772_32205	COG1132	(ABC) transporter
LO772_32225	COG2267	carboxylic ester hydrolase activity
LO772_32230	COG2084	Dehydrogenase
LO772_32245	COG1929	Belongs to the glycerate kinase type-1 family
LO772_32280	COG1309	transcriptional regulator
LO772_32285	COG1021	2,3-dihydroxybenzoate-AMP ligase
LO772_32310	COG0183	Belongs to the thiolase family
LO772_32315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_32325	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_32340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LO772_32370	COG1024	Enoyl-CoA hydratase
LO772_32385	COG1024	Enoyl-CoA hydratase
LO772_32390	COG1960	acyl-CoA dehydrogenase activity
LO772_32400	COG1960	acyl-CoA dehydrogenase activity
LO772_32445	COG0667	Aldo Keto reductase
LO772_32470	COG0640	Transcriptional regulator
LO772_32490	COG2801	Transposase and inactivated derivatives
LO772_32540	COG0477	Major facilitator Superfamily
LO772_32560	COG0159	tryptophan synthase activity
LO772_32595	COG2217	Heavy metal translocating P-type atpase
LO772_32625	COG2197	response regulator
LO772_32635	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_32675	COG2124	cytochrome p450
LO772_32680	COG4565	transcriptional regulatory protein
LO772_32685	COG3290	protein histidine kinase activity
LO772_32690	COG1301	dicarboxylic acid transport
LO772_32695	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LO772_32695	COG1024	Enoyl-CoA hydratase
LO772_32700	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LO772_32725	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LO772_32750	COG0298	carbon dioxide binding
LO772_32755	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LO772_32760	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LO772_32765	COG0375	protein maturation
LO772_32840	COG1595	DNA-templated transcription, initiation
LO772_32845	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LO772_32850	COG0657	acetylesterase activity
LO772_32865	COG0454	-acetyltransferase
LO772_32865	COG0456	acetyltransferase
LO772_32885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO772_32930	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LO772_32930	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LO772_32935	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LO772_32945	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LO772_32950	COG0523	cobalamin synthesis protein
LO772_32955	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LO772_32960	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LO772_32990	COG1302	Protein conserved in bacteria
LO772_33005	COG1595	DNA-templated transcription, initiation
LO772_33015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO772_33040	COG1024	Enoyl-CoA hydratase
LO772_33045	COG1309	transcriptional regulator
LO772_33055	COG3250	beta-galactosidase activity
LO772_33110	COG1116	anion transmembrane transporter activity
LO772_33115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO772_33120	COG1802	Transcriptional regulator
LO772_33160	COG1595	DNA-templated transcription, initiation
LO772_33165	COG2409	Drug exporters of the RND superfamily
LO772_33175	COG0745	RESPONSE REGULATOR receiver
LO772_33180	COG5002	protein histidine kinase activity
LO772_33195	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LO772_33210	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LO772_33245	COG2124	cytochrome p450
LO772_33290	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_33315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_33320	COG1024	Enoyl-CoA hydratase
LO772_33345	COG1960	acyl-CoA dehydrogenase activity
LO772_33350	COG1960	acyl-CoA dehydrogenase activity
LO772_33360	COG1024	Enoyl-CoA hydratase
LO772_33365	COG0183	Belongs to the thiolase family
LO772_33370	COG1960	acyl-CoA dehydrogenase activity
LO772_33375	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_33385	COG0183	Belongs to the thiolase family
LO772_33400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO772_33430	COG0277	FAD linked oxidase domain protein
LO772_33440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LO772_33450	COG1733	regulation of RNA biosynthetic process
LO772_33455	COG0702	epimerase
LO772_33465	COG1252	NADH dehydrogenase
LO772_33470	COG1595	DNA-templated transcription, initiation
LO772_33515	COG4221	oxidoreductase activity
LO772_33550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO772_33595	COG1131	(ABC) transporter
LO772_33610	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LO772_33620	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LO772_33635	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_33640	COG3386	PFAM SMP-30 Gluconolaconase
LO772_33650	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_33695	COG2197	response regulator
LO772_33700	COG3851	Histidine kinase
LO772_33705	COG0577	efflux transmembrane transporter activity
LO772_33705	COG1136	(ABC) transporter
LO772_33710	COG0672	)-iron permease
LO772_33715	COG2837	iron assimilation
LO772_33720	COG2822	iron ion transport
LO772_33760	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LO772_33790	COG0667	Aldo Keto reductase
LO772_33795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LO772_33805	COG0583	DNA-binding transcription factor activity
LO772_33830	COG1063	alcohol dehydrogenase
LO772_33850	COG0330	HflC and HflK could
LO772_33855	COG0586	Pfam SNARE associated Golgi protein
LO772_33905	COG2079	MmgE PrpD family protein
LO772_33910	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LO772_33920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LO772_33945	COG1024	Enoyl-CoA hydratase
LO772_34015	COG1012	belongs to the aldehyde dehydrogenase family
LO772_34040	COG0110	maltose O-acetyltransferase activity
LO772_34055	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_34095	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_34100	COG3250	beta-galactosidase activity
LO772_34120	COG3507	Belongs to the glycosyl hydrolase 43 family
LO772_34155	COG0583	DNA-binding transcription factor activity
LO772_34165	COG3540	Alkaline phosphatase
LO772_34170	COG0515	serine threonine protein kinase
LO772_34170	COG2815	serine threonine protein kinase
LO772_34180	COG3467	pyridoxamine 5'-phosphate
LO772_34210	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_34215	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LO772_34235	COG0243	molybdopterin cofactor binding
LO772_34245	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LO772_34260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_34270	COG1960	acyl-CoA dehydrogenase activity
LO772_34315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LO772_34325	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LO772_34355	COG4585	Histidine kinase
LO772_34360	COG2197	response regulator
LO772_34370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LO772_34405	COG0028	Belongs to the TPP enzyme family
LO772_34425	COG2124	cytochrome p450
LO772_34435	COG1132	(ABC) transporter
LO772_34450	COG2124	cytochrome p450
LO772_34465	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO772_34480	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LO772_34505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LO772_34515	COG2188	Transcriptional regulator
LO772_34520	COG1063	alcohol dehydrogenase
LO772_34530	COG1942	4-Oxalocrotonate Tautomerase
LO772_34565	COG1116	anion transmembrane transporter activity
LO772_34570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO772_34575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO772_34580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO772_34590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LO772_34595	COG4569	acetaldehyde dehydrogenase (acetylating) activity
LO772_34605	COG1414	Transcriptional regulator
LO772_34640	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO772_34655	COG3540	Alkaline phosphatase
LO772_34665	COG1024	Enoyl-CoA hydratase
LO772_34675	COG1960	acyl-CoA dehydrogenase activity
LO772_34700	COG0179	Fumarylacetoacetate (FAA) hydrolase
LO772_34740	COG0477	Major facilitator Superfamily
LO772_34750	COG1742	UPF0060 membrane protein
LO772_34765	COG1309	transcriptional regulator
LO772_34770	COG0673	inositol 2-dehydrogenase activity
LO772_34790	COG1028	Short-chain dehydrogenase reductase Sdr
LO772_34825	COG1063	alcohol dehydrogenase
LO772_34860	COG1946	Acyl-CoA thioesterase
LO772_34885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LO772_34890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_34900	COG0243	molybdopterin cofactor binding
LO772_34905	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LO772_34910	COG1309	transcriptional regulator
LO772_34925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO772_34930	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
LO772_34935	COG0477	Major facilitator Superfamily
LO772_34940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LO772_34960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LO772_34980	COG3654	unkown
LO772_35020	COG0739	heme binding
LO772_35045	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LO772_35055	COG1960	acyl-CoA dehydrogenase activity
LO772_35060	COG1960	acyl-CoA dehydrogenase activity
LO772_35080	COG1021	2,3-dihydroxybenzoate-AMP ligase
LO772_35085	COG1960	acyl-CoA dehydrogenase activity
LO772_35090	COG1960	acyl-CoA dehydrogenase activity
LO772_35095	COG1960	acyl-CoA dehydrogenase activity
LO772_35110	COG0183	Belongs to the thiolase family
LO772_35130	COG2072	flavoprotein involved in K transport
LO772_35150	COG1960	acyl-CoA dehydrogenase activity
LO772_35155	COG1960	acyl-CoA dehydrogenase activity
LO772_35180	COG1960	acyl-CoA dehydrogenase activity
LO772_35185	COG0640	Transcriptional regulator
LO772_35205	COG1609	Transcriptional regulator
LO772_35265	COG0477	Major facilitator Superfamily
LO772_35295	COG0187	DNA topoisomerase II activity
LO772_35300	COG0583	DNA-binding transcription factor activity
LO772_35310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO772_35320	COG0601	transmembrane transport
LO772_35325	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO772_35345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO772_35350	COG0492	ferredoxin-NADP+ reductase activity
LO772_35385	COG3804	dihydrodipicolinate reductase
LO772_35415	COG1695	Transcriptional regulator
LO772_35440	COG2205	protein histidine kinase activity
LO772_35570	COG3290	protein histidine kinase activity
LO772_35575	COG4565	transcriptional regulatory protein
LO772_35600	COG4221	oxidoreductase activity
LO772_35610	COG1304	FMN binding
LO772_35620	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LO772_35630	COG1609	Transcriptional regulator
LO772_35640	COG0655	NAD(P)H dehydrogenase (quinone) activity