locus-tag	class	description
FNA67_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FNA67_00010	COG0592	DNA-directed DNA polymerase activity
FNA67_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FNA67_00020	COG0187	DNA topoisomerase II activity
FNA67_00030	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNA67_00055	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FNA67_00070	COG0738	Major facilitator superfamily
FNA67_00085	COG0667	Aldo Keto reductase
FNA67_00090	COG2378	regulation of single-species biofilm formation
FNA67_00095	COG0596	Alpha beta hydrolase
FNA67_00120	COG3655	Transcriptional regulator
FNA67_00130	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNA67_00140	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FNA67_00155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNA67_00160	COG0840	transmembrane signaling receptor activity
FNA67_00165	COG1012	belongs to the aldehyde dehydrogenase family
FNA67_00175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_00180	COG0601	transmembrane transport
FNA67_00190	COG2186	Transcriptional regulator
FNA67_00215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNA67_00220	COG2159	amidohydrolase
FNA67_00235	COG0473	3-isopropylmalate dehydrogenase activity
FNA67_00235	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNA67_00240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNA67_00250	COG1448	Aminotransferase
FNA67_00280	COG0110	maltose O-acetyltransferase activity
FNA67_00285	COG0583	DNA-binding transcription factor activity
FNA67_00295	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNA67_00310	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNA67_00320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNA67_00330	COG2226	methyltransferase
FNA67_00350	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FNA67_00365	COG0367	asparagine synthase
FNA67_00375	COG0438	transferase activity, transferring glycosyl groups
FNA67_00380	COG0438	transferase activity, transferring glycosyl groups
FNA67_00385	COG0367	asparagine synthase
FNA67_00400	COG2226	methyltransferase
FNA67_00410	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNA67_00420	COG2226	methyltransferase
FNA67_00455	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FNA67_00500	COG4964	Belongs to the GSP D family
FNA67_00520	COG4964	Belongs to the GSP D family
FNA67_00540	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
FNA67_00545	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
FNA67_00550	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FNA67_00555	COG1012	belongs to the aldehyde dehydrogenase family
FNA67_00620	COG0469	pyruvate kinase activity
FNA67_00630	COG3750	Belongs to the UPF0335 family
FNA67_00635	COG1309	transcriptional regulator
FNA67_00640	COG0765	amino acid transport
FNA67_00645	COG0765	amino acid transport
FNA67_00655	COG1446	asparaginase
FNA67_00660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA67_00665	COG1609	Transcriptional regulator
FNA67_00670	COG1940	carbohydrate kinase activity
FNA67_00675	COG3142	Participates in the control of copper homeostasis
FNA67_00685	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FNA67_00690	COG3108	Peptidase M15
FNA67_00700	COG2989	Protein conserved in bacteria
FNA67_00705	COG0129	dihydroxy-acid dehydratase activity
FNA67_00710	COG0363	glucosamine-6-phosphate deaminase activity
FNA67_00715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FNA67_00720	COG2971	BadF BadG BcrA BcrD
FNA67_00735	COG1492	cobalamin metabolic process
FNA67_00740	COG1797	cobyrinic acid a,c-diamide synthase activity
FNA67_00750	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
FNA67_00780	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
FNA67_00790	COG0159	tryptophan synthase activity
FNA67_00795	COG0133	tryptophan synthase activity
FNA67_00800	COG0135	phosphoribosylanthranilate isomerase activity
FNA67_00810	COG0776	regulation of translation
FNA67_00815	COG0616	signal peptide processing
FNA67_00825	COG0539	negative regulation of cytoplasmic translation
FNA67_00830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FNA67_00875	COG3142	Participates in the control of copper homeostasis
FNA67_00880	COG2378	regulation of single-species biofilm formation
FNA67_00900	COG0667	Aldo Keto reductase
FNA67_00910	COG1216	Glycosyl transferase, family 2
FNA67_00910	COG1442	glycosyl transferase family 8
FNA67_00915	COG1442	glycosyl transferase family 8
FNA67_00925	COG0072	phenylalanine-tRNA ligase activity
FNA67_00925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNA67_00940	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FNA67_00945	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FNA67_00950	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FNA67_00955	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNA67_00975	COG0840	transmembrane signaling receptor activity
FNA67_00980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FNA67_01000	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FNA67_01010	COG1968	undecaprenyl-diphosphatase activity
FNA67_01060	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNA67_01065	COG1742	UPF0060 membrane protein
FNA67_01175	COG1598	PFAM Uncharacterised protein family UPF0150
FNA67_01395	COG3795	YCII-related domain
FNA67_01400	COG1376	ErfK ybiS ycfS ynhG family protein
FNA67_01425	COG1137	ATPase activity
FNA67_01430	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FNA67_01435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FNA67_01440	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA67_01450	COG0071	Belongs to the small heat shock protein (HSP20) family
FNA67_01475	COG2162	N-hydroxyarylamine O-acetyltransferase activity
FNA67_01485	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
FNA67_01490	COG0745	RESPONSE REGULATOR receiver
FNA67_01495	COG2205	protein histidine kinase activity
FNA67_01505	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
FNA67_01505	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
FNA67_01525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FNA67_01530	COG4952	isomerase
FNA67_01535	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_01535	COG3347	Dehydrogenase
FNA67_01540	COG1349	DNA-binding transcription factor activity
FNA67_01545	COG1879	ABC-type sugar transport system periplasmic component
FNA67_01550	COG1129	ABC transporter
FNA67_01555	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNA67_01575	COG1609	Transcriptional regulator
FNA67_01585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNA67_01585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FNA67_01595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNA67_01605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNA67_01610	COG3474	cytochrome
FNA67_01615	COG1605	Chorismate mutase
FNA67_01615	COG0077	Prephenate dehydratase
FNA67_01620	COG0519	Catalyzes the synthesis of GMP from XMP
FNA67_01620	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNA67_01625	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNA67_01630	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
FNA67_01645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FNA67_01650	COG1846	Transcriptional regulator
FNA67_01660	COG0477	Major facilitator Superfamily
FNA67_01690	COG2171	N-acyltransferase activity
FNA67_01700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNA67_01710	COG0101	tRNA pseudouridine synthase activity
FNA67_01720	COG0242	peptide deformylase activity
FNA67_01725	COG1322	Protein conserved in bacteria
FNA67_01735	COG0667	Aldo Keto reductase
FNA67_01740	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_01775	COG0583	DNA-binding transcription factor activity
FNA67_01815	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNA67_01830	COG3454	Phosphonate metabolism
FNA67_01835	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FNA67_01840	COG0583	DNA-binding transcription factor activity
FNA67_01845	COG2986	histidine ammonia-lyase
FNA67_01850	COG1732	Glycine betaine
FNA67_01855	COG1174	glycine betaine transport
FNA67_01860	COG1125	glycine betaine transport
FNA67_01865	COG1174	glycine betaine transport
FNA67_01870	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNA67_01890	COG0251	oxidation-reduction process
FNA67_01900	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FNA67_01905	COG1959	2 iron, 2 sulfur cluster binding
FNA67_01915	COG0803	Belongs to the bacterial solute-binding protein 9 family
FNA67_01920	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNA67_01940	COG0523	cobalamin synthesis protein
FNA67_01990	COG3795	YCII-related domain
FNA67_01995	COG4941	Belongs to the sigma-70 factor family
FNA67_02010	COG0789	Transcriptional regulator
FNA67_02015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FNA67_02025	COG0747	negative chemotaxis
FNA67_02030	COG1396	sequence-specific DNA binding
FNA67_02030	COG1917	Cupin 2, conserved barrel domain protein
FNA67_02035	COG0601	transmembrane transport
FNA67_02040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_02045	COG0444	Belongs to the ABC transporter superfamily
FNA67_02050	COG4608	Belongs to the ABC transporter superfamily
FNA67_02060	COG0729	surface antigen
FNA67_02085	COG2197	response regulator
FNA67_02120	COG0673	inositol 2-dehydrogenase activity
FNA67_02135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNA67_02140	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FNA67_02145	COG1596	polysaccharide export
FNA67_02170	COG1940	carbohydrate kinase activity
FNA67_02175	COG2182	Extracellular solute-binding protein
FNA67_02180	COG1175	transmembrane transport
FNA67_02185	COG0395	ABC-type sugar transport system, permease component
FNA67_02190	COG0165	Argininosuccinate lyase
FNA67_02195	COG3842	ATPase activity
FNA67_02210	COG3842	ATPase activity
FNA67_02215	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNA67_02220	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNA67_02235	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FNA67_02240	COG0583	DNA-binding transcription factor activity
FNA67_02245	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNA67_02260	COG3806	Anti-sigma factor
FNA67_02265	COG1595	DNA-templated transcription, initiation
FNA67_02280	COG0300	oxidoreductase activity
FNA67_02290	COG1121	(ABC) transporter
FNA67_02295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNA67_02300	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FNA67_02310	COG1802	Transcriptional regulator
FNA67_02320	COG1175	transmembrane transport
FNA67_02325	COG3833	ABC-type maltose transport systems, permease component
FNA67_02340	COG3707	response regulator
FNA67_02345	COG1116	anion transmembrane transporter activity
FNA67_02345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNA67_02350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNA67_02355	COG2146	nitrite reductase [NAD(P)H] activity
FNA67_02360	COG2116	formate transmembrane transporter activity
FNA67_02365	COG1648	precorrin-2 dehydrogenase activity
FNA67_02365	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNA67_02380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNA67_02400	COG0385	Bile acid
FNA67_02405	COG0747	negative chemotaxis
FNA67_02440	COG1024	Enoyl-CoA hydratase
FNA67_02445	COG1022	Amp-dependent synthetase and ligase
FNA67_02445	COG3320	Male sterility
FNA67_02480	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNA67_02500	COG0450	alkyl hydroperoxide reductase
FNA67_02515	COG0765	amino acid transport
FNA67_02525	COG3422	double-strand break repair
FNA67_02540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FNA67_02540	COG1017	nitric oxide dioxygenase activity
FNA67_02580	COG0481	GTPase activity
FNA67_02595	COG0667	Aldo Keto reductase
FNA67_02605	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_02625	COG2223	nitrite transmembrane transporter activity
FNA67_02640	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
FNA67_02650	COG0346	lactoylglutathione lyase activity
FNA67_02655	COG0747	negative chemotaxis
FNA67_02660	COG0601	transmembrane transport
FNA67_02665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_02670	COG0444	Belongs to the ABC transporter superfamily
FNA67_02675	COG4608	Belongs to the ABC transporter superfamily
FNA67_02695	COG2205	protein histidine kinase activity
FNA67_02700	COG0802	atpase or kinase
FNA67_02705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FNA67_02715	COG1074	ATP-dependent DNA helicase activity
FNA67_02720	COG3118	belongs to the thioredoxin family
FNA67_02730	COG3118	belongs to the thioredoxin family
FNA67_02735	COG0285	dihydrofolate synthase activity
FNA67_02740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FNA67_02745	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FNA67_02750	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FNA67_02765	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FNA67_02770	COG0706	membrane insertase activity
FNA67_02775	COG0594	ribonuclease P activity
FNA67_02780	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FNA67_02790	COG3852	Histidine kinase
FNA67_02830	COG0464	growth
FNA67_02895	COG4227	nucleotidyltransferase activity
FNA67_02955	COG1120	ATPase activity
FNA67_02960	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNA67_02965	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNA67_02980	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
FNA67_03015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_03020	COG0444	Belongs to the ABC transporter superfamily
FNA67_03040	COG3473	Maleate cis-trans isomerase
FNA67_03045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNA67_03050	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNA67_03060	COG1802	Transcriptional regulator
FNA67_03075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNA67_03080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNA67_03100	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_03105	COG4172	Belongs to the ABC transporter superfamily
FNA67_03110	COG0747	negative chemotaxis
FNA67_03135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNA67_03165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNA67_03170	COG4608	Belongs to the ABC transporter superfamily
FNA67_03180	COG4166	transmembrane transport
FNA67_03185	COG0601	transmembrane transport
FNA67_03190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_03205	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNA67_03210	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNA67_03215	COG1177	transmembrane transport
FNA67_03220	COG3842	ATPase activity
FNA67_03225	COG0402	S-adenosylhomocysteine deaminase activity
FNA67_03235	COG1473	amidohydrolase
FNA67_03240	COG1040	competence protein
FNA67_03255	COG2198	Histidine kinase
FNA67_03255	COG0643	Histidine kinase
FNA67_03260	COG0835	chemotaxis
FNA67_03265	COG0840	transmembrane signaling receptor activity
FNA67_03270	COG0835	chemotaxis
FNA67_03280	COG2201	protein-glutamate methylesterase activity
FNA67_03325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA67_03350	COG0714	Associated with various cellular activities
FNA67_03385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA67_03390	COG4166	transmembrane transport
FNA67_03395	COG4608	Belongs to the ABC transporter superfamily
FNA67_03400	COG0444	Belongs to the ABC transporter superfamily
FNA67_03405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_03410	COG0601	transmembrane transport
FNA67_03425	COG0514	ATP-dependent DNA helicase (RecQ)
FNA67_03430	COG1960	acyl-CoA dehydrogenase activity
FNA67_03445	COG1082	Xylose isomerase domain protein TIM barrel
FNA67_03450	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_03455	COG0745	RESPONSE REGULATOR receiver
FNA67_03460	COG5002	protein histidine kinase activity
FNA67_03475	COG1073	alpha beta
FNA67_03485	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_03525	COG3622	Belongs to the hyi family
FNA67_03540	COG3842	ATPase activity
FNA67_03545	COG0673	inositol 2-dehydrogenase activity
FNA67_03555	COG0395	ABC-type sugar transport system, permease component
FNA67_03560	COG1175	transmembrane transport
FNA67_03570	COG0583	DNA-binding transcription factor activity
FNA67_03575	COG1309	transcriptional regulator
FNA67_03580	COG0673	inositol 2-dehydrogenase activity
FNA67_03595	COG4821	SIS domain
FNA67_03605	COG0456	acetyltransferase
FNA67_03610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNA67_03630	COG4172	Belongs to the ABC transporter superfamily
FNA67_03635	COG1012	belongs to the aldehyde dehydrogenase family
FNA67_03645	COG2267	carboxylic ester hydrolase activity
FNA67_03655	COG3191	aminopeptidase activity
FNA67_03665	COG1063	alcohol dehydrogenase
FNA67_03670	COG2514	catechol 2,3-dioxygenase activity
FNA67_03685	COG2207	Transcriptional regulator
FNA67_03720	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_03725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA67_03740	COG0174	glutamine synthetase
FNA67_03745	COG0531	amino acid
FNA67_03760	COG0745	RESPONSE REGULATOR receiver
FNA67_03765	COG0704	Plays a role in the regulation of phosphate uptake
FNA67_03770	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FNA67_03780	COG0573	inorganic phosphate transmembrane transporter activity
FNA67_03785	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FNA67_03790	COG5002	protein histidine kinase activity
FNA67_03795	COG2326	polyphosphate kinase activity
FNA67_03805	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNA67_03810	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FNA67_03815	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FNA67_03825	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FNA67_03835	COG0717	Belongs to the dCTP deaminase family
FNA67_03840	COG1064	alcohol dehydrogenase
FNA67_03885	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_03905	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNA67_03915	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNA67_03945	COG4977	sequence-specific DNA binding
FNA67_03970	COG1846	Transcriptional regulator
FNA67_03975	COG2197	response regulator
FNA67_03985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA67_03990	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
FNA67_04010	COG0167	dihydroorotate dehydrogenase activity
FNA67_04020	COG0572	uridine kinase
FNA67_04025	COG1201	RNA secondary structure unwinding
FNA67_04050	COG0730	response to heat
FNA67_04070	COG1970	mechanosensitive ion channel activity
FNA67_04075	COG4566	intracellular signal transduction
FNA67_04080	COG0156	8-amino-7-oxononanoate synthase activity
FNA67_04085	COG0840	transmembrane signaling receptor activity
FNA67_04090	COG1917	Cupin 2, conserved barrel domain protein
FNA67_04090	COG4977	sequence-specific DNA binding
FNA67_04095	COG1486	melibiose metabolic process
FNA67_04110	COG2885	chlorophyll binding
FNA67_04130	COG1376	ErfK ybiS ycfS ynhG family protein
FNA67_04215	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FNA67_04230	COG0515	serine threonine protein kinase
FNA67_04250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FNA67_04255	COG0424	maF-like protein
FNA67_04260	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FNA67_04290	COG3685	Protein conserved in bacteria
FNA67_04295	COG1473	amidohydrolase
FNA67_04305	COG3237	CsbD-like
FNA67_04315	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_04325	COG1609	Transcriptional regulator
FNA67_04335	COG4209	transmembrane transport
FNA67_04340	COG3833	ABC-type maltose transport systems, permease component
FNA67_04350	COG3842	ATPase activity
FNA67_04355	COG1280	lysine exporter protein (LysE YggA)
FNA67_04360	COG1744	ABC transporter substrate-binding protein PnrA-like
FNA67_04405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNA67_04410	COG2084	Dehydrogenase
FNA67_04415	COG2207	Transcriptional regulator
FNA67_04420	COG0747	negative chemotaxis
FNA67_04425	COG0601	transmembrane transport
FNA67_04430	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_04435	COG4172	Belongs to the ABC transporter superfamily
FNA67_04440	COG1486	melibiose metabolic process
FNA67_04450	COG4977	sequence-specific DNA binding
FNA67_04470	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNA67_04505	COG0366	Alpha amylase catalytic
FNA67_04515	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FNA67_04520	COG0679	Auxin Efflux Carrier
FNA67_04530	COG1473	amidohydrolase
FNA67_04535	COG2086	electron transfer activity
FNA67_04540	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
FNA67_04550	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FNA67_04555	COG0489	protein tyrosine kinase activity
FNA67_04560	COG2723	6-phospho-beta-galactosidase activity
FNA67_04565	COG2226	methyltransferase
FNA67_04570	COG1653	transport
FNA67_04575	COG1175	transmembrane transport
FNA67_04580	COG0395	ABC-type sugar transport system, permease component
FNA67_04585	COG1609	Transcriptional regulator
FNA67_04590	COG0366	Alpha amylase catalytic
FNA67_04605	COG4172	Belongs to the ABC transporter superfamily
FNA67_04620	COG0747	negative chemotaxis
FNA67_04625	COG1178	ABC-type Fe3 transport system permease component
FNA67_04630	COG1840	ABC-type Fe3 transport system, periplasmic component
FNA67_04650	COG1388	LysM domain
FNA67_04650	COG1376	ErfK ybiS ycfS ynhG family protein
FNA67_04655	COG2818	Glycosylase
FNA67_04670	COG0124	histidyl-tRNA synthetase
FNA67_04675	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FNA67_04680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FNA67_04720	COG0459	protein refolding
FNA67_04725	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FNA67_04740	COG2204	response regulator
FNA67_04760	COG2267	carboxylic ester hydrolase activity
FNA67_04765	COG0742	ribosomal rna small subunit methyltransferase
FNA67_04780	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FNA67_04785	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FNA67_04790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FNA67_04805	COG0590	tRNA wobble adenosine to inosine editing
FNA67_04810	COG1752	Esterase of the alpha-beta hydrolase superfamily
FNA67_04815	COG0151	Belongs to the GarS family
FNA67_04820	COG1570	exodeoxyribonuclease VII activity
FNA67_04860	COG0785	Cytochrome C biogenesis protein
FNA67_04875	COG1309	transcriptional regulator
FNA67_04880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNA67_04890	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNA67_04900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNA67_04905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FNA67_04915	COG1116	anion transmembrane transporter activity
FNA67_04920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNA67_04940	COG0196	riboflavin kinase activity
FNA67_04945	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNA67_04955	COG3453	Protein conserved in bacteria
FNA67_04955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNA67_05000	COG3842	ATPase activity
FNA67_05020	COG1011	Hydrolase
FNA67_05025	COG0483	inositol monophosphate 1-phosphatase activity
FNA67_05035	COG1283	sodium-dependent phosphate transmembrane transporter activity
FNA67_05045	COG1609	Transcriptional regulator
FNA67_05050	COG2308	Evidence 4 Homologs of previously reported genes of
FNA67_05060	COG1305	Transglutaminase-like
FNA67_05070	COG2249	NAD(P)H dehydrogenase (quinone) activity
FNA67_05080	COG0402	S-adenosylhomocysteine deaminase activity
FNA67_05085	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNA67_05090	COG1116	anion transmembrane transporter activity
FNA67_05125	COG0446	pyridine nucleotide-disulphide oxidoreductase
FNA67_05155	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FNA67_05160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FNA67_05170	COG0667	Aldo Keto reductase
FNA67_05175	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FNA67_05205	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FNA67_05210	COG0109	protoheme IX farnesyltransferase activity
FNA67_05215	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
FNA67_05240	COG0612	Peptidase, M16
FNA67_05255	COG1678	Uncharacterized ACR, COG1678
FNA67_05265	COG0678	peroxiredoxin activity
FNA67_05275	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FNA67_05280	COG0509	glycine decarboxylation via glycine cleavage system
FNA67_05285	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNA67_05290	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FNA67_05305	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FNA67_05315	COG0356	it plays a direct role in the translocation of protons across the membrane
FNA67_05325	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FNA67_05345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FNA67_05350	COG1196	nuclear chromosome segregation
FNA67_05380	COG1573	uracil-dna glycosylase
FNA67_05395	COG0521	Mo-molybdopterin cofactor biosynthetic process
FNA67_05400	COG0142	geranyltranstransferase activity
FNA67_05420	COG0752	glycyl-tRNA synthetase alpha subunit
FNA67_05435	COG1704	LemA family
FNA67_05450	COG0751	glycine-tRNA ligase activity
FNA67_05455	COG0328	RNA-DNA hybrid ribonuclease activity
FNA67_05465	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FNA67_05470	COG0574	Belongs to the PEP-utilizing enzyme family
FNA67_05470	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNA67_05475	COG3773	Cell wall hydrolase
FNA67_05485	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
FNA67_05490	COG0354	folic acid binding
FNA67_05495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNA67_05520	COG0277	FAD linked oxidase domain protein
FNA67_05525	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
FNA67_05530	COG0406	alpha-ribazole phosphatase activity
FNA67_05535	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FNA67_05545	COG1722	exodeoxyribonuclease VII activity
FNA67_05550	COG0123	including yeast histone deacetylase and acetoin utilization protein
FNA67_05555	COG0009	L-threonylcarbamoyladenylate synthase
FNA67_05575	COG0259	pyridoxamine-phosphate oxidase activity
FNA67_05580	COG0484	heat shock protein binding
FNA67_05600	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNA67_05605	COG1129	ABC transporter
FNA67_05645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNA67_05650	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FNA67_05655	COG0747	negative chemotaxis
FNA67_05700	COG3118	belongs to the thioredoxin family
FNA67_05715	COG1091	dTDP-4-dehydrorhamnose reductase activity
FNA67_05760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNA67_05770	COG2373	Large extracellular alpha-helical protein
FNA67_05775	COG4953	penicillin-binding protein 1C
FNA67_05815	COG0640	Transcriptional regulator
FNA67_05835	COG3453	Protein conserved in bacteria
FNA67_05835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNA67_05850	COG0745	RESPONSE REGULATOR receiver
FNA67_05870	COG4166	transmembrane transport
FNA67_05880	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_05885	COG2186	Transcriptional regulator
FNA67_05890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNA67_05890	COG0473	3-isopropylmalate dehydrogenase activity
FNA67_05895	COG1414	Transcriptional regulator
FNA67_05900	COG1461	Dihydroxyacetone kinase
FNA67_05905	COG2376	Dihydroxyacetone kinase
FNA67_05910	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNA67_05935	COG0747	negative chemotaxis
FNA67_05945	COG0444	Belongs to the ABC transporter superfamily
FNA67_05955	COG2188	Transcriptional regulator
FNA67_05960	COG1363	Peptidase, m42
FNA67_05965	COG1846	Transcriptional regulator
FNA67_05975	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FNA67_05980	COG1917	Cupin 2, conserved barrel domain protein
FNA67_05985	COG5285	phytanoyl-CoA dioxygenase
FNA67_05990	COG0527	aspartate kinase activity
FNA67_05995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA67_06000	COG0765	amino acid transport
FNA67_06005	COG0765	amino acid transport
FNA67_06010	COG1126	abc transporter atp-binding protein
FNA67_06020	COG0583	DNA-binding transcription factor activity
FNA67_06025	COG2226	methyltransferase
FNA67_06030	COG3119	arylsulfatase activity
FNA67_06055	COG0583	DNA-binding transcription factor activity
FNA67_06070	COG0673	inositol 2-dehydrogenase activity
FNA67_06080	COG0444	Belongs to the ABC transporter superfamily
FNA67_06100	COG0601	transmembrane transport
FNA67_06105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_06110	COG0405	Gamma-glutamyltransferase
FNA67_06115	COG3842	ATPase activity
FNA67_06120	COG0395	ABC-type sugar transport system, permease component
FNA67_06135	COG1053	succinate dehydrogenase
FNA67_06135	COG3976	FMN-binding domain protein
FNA67_06140	COG1609	Transcriptional regulator
FNA67_06155	COG0673	inositol 2-dehydrogenase activity
FNA67_06160	COG2186	Transcriptional regulator
FNA67_06165	COG0747	negative chemotaxis
FNA67_06180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNA67_06185	COG0444	Belongs to the ABC transporter superfamily
FNA67_06195	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FNA67_06195	COG1940	carbohydrate kinase activity
FNA67_06200	COG1136	(ABC) transporter
FNA67_06225	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FNA67_06240	COG1396	sequence-specific DNA binding
FNA67_06250	COG1063	alcohol dehydrogenase
FNA67_06255	COG0673	inositol 2-dehydrogenase activity
FNA67_06260	COG1802	Transcriptional regulator
FNA67_06270	COG1760	l-serine dehydratase
FNA67_06295	COG1175	transmembrane transport
FNA67_06300	COG0395	ABC-type sugar transport system, permease component
FNA67_06305	COG3842	ATPase activity
FNA67_06310	COG0584	glycerophosphoryl diester phosphodiesterase
FNA67_06315	COG1349	DNA-binding transcription factor activity
FNA67_06325	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNA67_06350	COG0433	COG0433 Predicted ATPase
FNA67_06360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FNA67_06375	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FNA67_06385	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNA67_06400	COG1006	Multisubunit Na H antiporter MnhC subunit
FNA67_06415	COG2212	antiporter activity
FNA67_06420	COG1320	monovalent cation:proton antiporter activity
FNA67_06425	COG4957	zinc ion binding
FNA67_06440	COG2166	iron-sulfur cluster assembly
FNA67_06450	COG2205	protein histidine kinase activity
FNA67_06470	COG2226	methyltransferase
FNA67_06520	COG4695	Portal protein
FNA67_06570	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FNA67_06600	COG1388	LysM domain
FNA67_06600	COG0791	NLP P60 protein
FNA67_06620	COG0745	RESPONSE REGULATOR receiver
FNA67_06625	COG5002	protein histidine kinase activity
FNA67_06655	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
FNA67_06660	COG1138	Cytochrome C-type biogenesis protein
FNA67_06665	COG3088	subunit of a heme lyase
FNA67_06675	COG0745	RESPONSE REGULATOR receiver
FNA67_06680	COG2205	protein histidine kinase activity
FNA67_06685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FNA67_06695	COG1136	(ABC) transporter
FNA67_06705	COG2202	Pas domain
FNA67_06705	COG2205	protein histidine kinase activity
FNA67_06710	COG0308	aminopeptidase N
FNA67_06715	COG1132	(ABC) transporter
FNA67_06720	COG1132	(ABC) transporter
FNA67_06725	COG1132	(ABC) transporter
FNA67_06740	COG3250	beta-galactosidase activity
FNA67_06745	COG0697	spore germination
FNA67_06755	COG2271	Major facilitator Superfamily
FNA67_06760	COG1309	transcriptional regulator
FNA67_06785	COG1233	COG1233 Phytoene dehydrogenase and related
FNA67_06790	COG2814	Major facilitator Superfamily
FNA67_06795	COG1846	Transcriptional regulator
FNA67_06800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNA67_06815	COG0625	glutathione transferase activity
FNA67_06820	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
FNA67_06825	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FNA67_06830	COG2202	Pas domain
FNA67_06830	COG2205	protein histidine kinase activity
FNA67_06840	COG1522	sequence-specific DNA binding
FNA67_06845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FNA67_06850	COG1376	ErfK ybiS ycfS ynhG family protein
FNA67_06855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FNA67_06870	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
FNA67_06875	COG0784	Response regulator, receiver
FNA67_06890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNA67_06905	COG0215	cysteine-tRNA ligase activity
FNA67_06925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNA67_06940	COG5265	(ABC) transporter
FNA67_06975	COG1609	Transcriptional regulator
FNA67_06985	COG3842	ATPase activity
FNA67_07000	COG0395	ABC-type sugar transport system, permease component
FNA67_07010	COG2186	Transcriptional regulator
FNA67_07020	COG0535	radical SAM domain protein
FNA67_07025	COG0535	radical SAM domain protein
FNA67_07030	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
FNA67_07035	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FNA67_07045	COG0583	DNA-binding transcription factor activity
FNA67_07050	COG0583	DNA-binding transcription factor activity
FNA67_07070	COG0191	fructose-bisphosphate aldolase activity
FNA67_07095	COG0546	phosphoglycolate phosphatase activity
FNA67_07105	COG1228	amidohydrolase
FNA67_07110	COG4608	Belongs to the ABC transporter superfamily
FNA67_07115	COG0444	Belongs to the ABC transporter superfamily
FNA67_07135	COG0006	proline dipeptidase activity
FNA67_07150	COG0667	Aldo Keto reductase
FNA67_07155	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNA67_07165	COG0789	Transcriptional regulator
FNA67_07175	COG0738	Major facilitator superfamily
FNA67_07195	COG0395	ABC-type sugar transport system, permease component
FNA67_07210	COG1737	Transcriptional regulator
FNA67_07240	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FNA67_07245	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FNA67_07250	COG0346	lactoylglutathione lyase activity
FNA67_07255	COG2111	Na H antiporter
FNA67_07255	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FNA67_07260	COG1006	Multisubunit Na H antiporter MnhC subunit
FNA67_07265	COG0651	ATP synthesis coupled electron transport
FNA67_07270	COG1863	multisubunit Na H antiporter MnhE subunit
FNA67_07275	COG2212	antiporter activity
FNA67_07280	COG1320	monovalent cation:proton antiporter activity
FNA67_07285	COG0586	Pfam SNARE associated Golgi protein
FNA67_07305	COG2207	Transcriptional regulator
FNA67_07310	COG1120	ATPase activity
FNA67_07340	COG1012	belongs to the aldehyde dehydrogenase family
FNA67_07350	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_07360	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNA67_07365	COG1012	belongs to the aldehyde dehydrogenase family
FNA67_07375	COG5441	Belongs to the UPF0261 family
FNA67_07400	COG3842	ATPase activity
FNA67_07415	COG0410	ABC transporter
FNA67_07420	COG0411	ABC transporter
FNA67_07435	COG0523	cobalamin synthesis protein
FNA67_07440	COG1228	amidohydrolase
FNA67_07450	COG3273	potassium ion transport
FNA67_07450	COG0471	metal ion transport
FNA67_07460	COG3971	2-oxopent-4-enoate hydratase activity
FNA67_07495	COG1846	Transcriptional regulator
FNA67_07505	COG0531	amino acid
FNA67_07515	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FNA67_07545	COG1177	transmembrane transport
FNA67_07550	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNA67_07555	COG3842	ATPase activity
FNA67_07560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNA67_07595	COG1609	Transcriptional regulator
FNA67_07605	COG1609	Transcriptional regulator
FNA67_07610	COG0363	glucosamine-6-phosphate deaminase activity
FNA67_07615	COG4821	SIS domain
FNA67_07635	COG1175	transmembrane transport
FNA67_07640	COG0395	ABC-type sugar transport system, permease component
FNA67_07650	COG3842	ATPase activity
FNA67_07655	COG0246	Mannitol dehydrogenase
FNA67_07660	COG1312	Catalyzes the dehydration of D-mannonate
FNA67_07690	COG0642	Histidine kinase
FNA67_07695	COG3842	ATPase activity
FNA67_07705	COG0395	ABC-type sugar transport system, permease component
FNA67_07710	COG1175	transmembrane transport
FNA67_07715	COG1653	transport
FNA67_07720	COG1609	Transcriptional regulator
FNA67_07730	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FNA67_07735	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FNA67_07740	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
FNA67_07745	COG2205	protein histidine kinase activity
FNA67_07750	COG0745	RESPONSE REGULATOR receiver
FNA67_07770	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNA67_07780	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
FNA67_07785	COG0395	ABC-type sugar transport system, permease component
FNA67_07795	COG1653	transport
FNA67_07805	COG0747	negative chemotaxis
FNA67_07810	COG0601	transmembrane transport
FNA67_07815	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_07820	COG4172	Belongs to the ABC transporter superfamily
FNA67_07825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FNA67_07830	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FNA67_07835	COG0454	-acetyltransferase
FNA67_07845	COG1215	transferase activity, transferring glycosyl groups
FNA67_07855	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
FNA67_07865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FNA67_07880	COG0747	negative chemotaxis
FNA67_07885	COG0601	transmembrane transport
FNA67_07915	COG1175	transmembrane transport
FNA67_07920	COG0395	ABC-type sugar transport system, permease component
FNA67_07925	COG0402	S-adenosylhomocysteine deaminase activity
FNA67_07930	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FNA67_07945	COG0402	S-adenosylhomocysteine deaminase activity
FNA67_07965	COG4266	Belongs to the allantoicase family
FNA67_08020	COG1175	transmembrane transport
FNA67_08040	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FNA67_08045	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNA67_08050	COG4948	Mandelate Racemase Muconate Lactonizing
FNA67_08055	COG3842	ATPase activity
FNA67_08060	COG0395	ABC-type sugar transport system, permease component
FNA67_08080	COG4948	Mandelate Racemase Muconate Lactonizing
FNA67_08085	COG4948	Mandelate Racemase Muconate Lactonizing
FNA67_08105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNA67_08145	COG1744	ABC transporter substrate-binding protein PnrA-like
FNA67_08160	COG0747	negative chemotaxis
FNA67_08165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_08170	COG0601	transmembrane transport
FNA67_08185	COG1737	Transcriptional regulator
FNA67_08195	COG0747	negative chemotaxis
FNA67_08200	COG0601	transmembrane transport
FNA67_08205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_08210	COG0444	Belongs to the ABC transporter superfamily
FNA67_08215	COG4608	Belongs to the ABC transporter superfamily
FNA67_08220	COG0596	Alpha beta hydrolase
FNA67_08230	COG1132	(ABC) transporter
FNA67_08235	COG1132	(ABC) transporter
FNA67_08295	COG2814	Major facilitator Superfamily
FNA67_08300	COG0583	DNA-binding transcription factor activity
FNA67_08305	COG0667	Aldo Keto reductase
FNA67_08320	COG3842	ATPase activity
FNA67_08325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FNA67_08330	COG3540	Alkaline phosphatase
FNA67_08335	COG0584	glycerophosphoryl diester phosphodiesterase
FNA67_08340	COG0395	ABC-type sugar transport system, permease component
FNA67_08345	COG1175	transmembrane transport
FNA67_08350	COG1653	transport
FNA67_08355	COG0783	Belongs to the Dps family
FNA67_08360	COG2140	Oxalate decarboxylase
FNA67_08370	COG0745	RESPONSE REGULATOR receiver
FNA67_08375	COG4566	intracellular signal transduction
FNA67_08380	COG4191	Histidine kinase
FNA67_08385	COG2205	protein histidine kinase activity
FNA67_08400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNA67_08410	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_08440	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNA67_08450	COG0583	DNA-binding transcription factor activity
FNA67_08475	COG0477	Major facilitator Superfamily
FNA67_08480	COG0477	Major facilitator Superfamily
FNA67_08500	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FNA67_08500	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNA67_08505	COG1490	D-aminoacyl-tRNA deacylase activity
FNA67_08510	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FNA67_08520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FNA67_08520	COG0519	Catalyzes the synthesis of GMP from XMP
FNA67_08535	COG1309	transcriptional regulator
FNA67_08565	COG1253	flavin adenine dinucleotide binding
FNA67_08570	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_08575	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
FNA67_08610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FNA67_08615	COG0305	Participates in initiation and elongation during chromosome replication
FNA67_08625	COG2855	membrane
FNA67_08645	COG1846	Transcriptional regulator
FNA67_08650	COG0583	DNA-binding transcription factor activity
FNA67_08665	COG0798	PFAM Bile acid sodium symporter
FNA67_08670	COG1393	Belongs to the ArsC family
FNA67_08680	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FNA67_08685	COG0360	Binds together with S18 to 16S ribosomal RNA
FNA67_08695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FNA67_08705	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FNA67_08710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNA67_08715	COG2207	Transcriptional regulator
FNA67_08720	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_08725	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FNA67_08730	COG1561	YicC-like family, N-terminal region
FNA67_08735	COG0194	GDP metabolic process
FNA67_08750	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FNA67_08755	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FNA67_08780	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FNA67_08810	COG0488	(ABC) transporter
FNA67_08825	COG0513	Belongs to the DEAD box helicase family
FNA67_08830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNA67_08855	COG0243	molybdopterin cofactor binding
FNA67_08860	COG0730	response to heat
FNA67_08870	COG0625	glutathione transferase activity
FNA67_08880	COG1228	amidohydrolase
FNA67_08905	COG0444	Belongs to the ABC transporter superfamily
FNA67_08910	COG0601	transmembrane transport
FNA67_08915	COG0747	negative chemotaxis
FNA67_08920	COG0667	Aldo Keto reductase
FNA67_08925	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_08945	COG1349	DNA-binding transcription factor activity
FNA67_08960	COG3842	ATPase activity
FNA67_08990	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FNA67_09020	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_09030	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_09050	COG0601	transmembrane transport
FNA67_09060	COG0444	Belongs to the ABC transporter superfamily
FNA67_09065	COG4608	Belongs to the ABC transporter superfamily
FNA67_09085	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FNA67_09095	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
FNA67_09100	COG4988	ABC transporter
FNA67_09110	COG1294	oxidase, subunit
FNA67_09145	COG0662	Cupin 2, conserved barrel domain protein
FNA67_09145	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FNA67_09165	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FNA67_09175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FNA67_09180	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
FNA67_09185	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_09195	COG2885	chlorophyll binding
FNA67_09195	COG3047	cAMP biosynthetic process
FNA67_09200	COG3743	rRNA binding
FNA67_09200	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FNA67_09210	COG0741	lytic transglycosylase activity
FNA67_09220	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FNA67_09225	COG1573	uracil-dna glycosylase
FNA67_09235	COG1758	RNA polymerase activity
FNA67_09245	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FNA67_09250	COG0736	holo-[acyl-carrier-protein] synthase activity
FNA67_09255	COG0681	Belongs to the peptidase S26 family
FNA67_09260	COG0571	ribonuclease III activity
FNA67_09265	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FNA67_09275	COG1381	Involved in DNA repair and RecF pathway recombination
FNA67_09280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNA67_09295	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FNA67_09315	COG1609	Transcriptional regulator
FNA67_09320	COG0113	porphobilinogen synthase activity
FNA67_09360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FNA67_09370	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNA67_09390	COG0416	fatty acid biosynthetic process
FNA67_09395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FNA67_09400	COG0776	regulation of translation
FNA67_09420	COG0477	Major facilitator Superfamily
FNA67_09435	COG0582	viral genome integration into host DNA
FNA67_09505	COG3750	Belongs to the UPF0335 family
FNA67_09515	COG0592	DNA-directed DNA polymerase activity
FNA67_09575	COG3567	Phage-associated protein, HI1409 family
FNA67_09760	COG4566	intracellular signal transduction
FNA67_09780	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_09785	COG3254	rhamnose metabolic process
FNA67_09810	COG1596	polysaccharide export
FNA67_09830	COG1612	heme a metabolic process
FNA67_09835	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FNA67_09845	COG5658	integral membrane protein
FNA67_09855	COG1819	glycosyl
FNA67_09860	COG0436	Aminotransferase
FNA67_09870	COG1494	fructose-1,6-bisphosphatase
FNA67_09885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNA67_09890	COG4221	oxidoreductase activity
FNA67_09900	COG0129	dihydroxy-acid dehydratase activity
FNA67_09920	COG2197	response regulator
FNA67_09930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNA67_09935	COG0579	oxidoreductase
FNA67_09975	COG2207	Transcriptional regulator
FNA67_09980	COG0300	oxidoreductase activity
FNA67_09985	COG0412	Dienelactone hydrolase
FNA67_10005	COG0346	lactoylglutathione lyase activity
FNA67_10010	COG1278	Cold shock
FNA67_10020	COG1272	protein, Hemolysin III
FNA67_10040	COG0052	Belongs to the universal ribosomal protein uS2 family
FNA67_10045	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FNA67_10050	COG0528	UMP kinase activity
FNA67_10055	COG0233	cytoplasmic translational termination
FNA67_10060	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FNA67_10065	COG0575	Belongs to the CDS family
FNA67_10070	COG0750	zinc metalloprotease
FNA67_10080	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNA67_10085	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNA67_10090	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNA67_10095	COG3494	Protein of unknown function (DUF1009)
FNA67_10100	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FNA67_10105	COG0372	Belongs to the citrate synthase family
FNA67_10125	COG3386	PFAM SMP-30 Gluconolaconase
FNA67_10130	COG0800	Aldolase
FNA67_10135	COG3734	2-keto-3-deoxy-galactonokinase
FNA67_10140	COG0129	dihydroxy-acid dehydratase activity
FNA67_10145	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FNA67_10160	COG1289	transmembrane transporter activity
FNA67_10175	COG0303	'Molybdopterin
FNA67_10180	COG0315	cyclic pyranopterin monophosphate synthase activity
FNA67_10185	COG0134	indole-3-glycerol-phosphate synthase activity
FNA67_10190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FNA67_10200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FNA67_10210	COG0149	triose-phosphate isomerase activity
FNA67_10215	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNA67_10220	COG0504	CTP synthase activity
FNA67_10230	COG3920	Histidine kinase
FNA67_10230	COG2202	Pas domain
FNA67_10235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FNA67_10240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FNA67_10245	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FNA67_10270	COG1253	flavin adenine dinucleotide binding
FNA67_10295	COG1984	allophanate hydrolase subunit 2
FNA67_10300	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
FNA67_10305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FNA67_10345	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNA67_10355	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNA67_10360	COG1940	carbohydrate kinase activity
FNA67_10365	COG1215	transferase activity, transferring glycosyl groups
FNA67_10380	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
FNA67_10420	COG4176	ABC-type proline glycine betaine transport system permease component
FNA67_10425	COG4175	Glycine betaine
FNA67_10425	COG0517	IMP dehydrogenase activity
FNA67_10430	COG1942	4-Oxalocrotonate Tautomerase
FNA67_10445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FNA67_10450	COG2072	flavoprotein involved in K transport
FNA67_10455	COG1737	Transcriptional regulator
FNA67_10460	COG1116	anion transmembrane transporter activity
FNA67_10465	COG2011	ABC-type metal ion transport system permease component
FNA67_10475	COG0673	inositol 2-dehydrogenase activity
FNA67_10480	COG3964	amidohydrolase
FNA67_10490	COG5002	protein histidine kinase activity
FNA67_10500	COG0745	RESPONSE REGULATOR receiver
FNA67_10505	COG3800	Transcriptional regulator
FNA67_10505	COG1396	sequence-specific DNA binding
FNA67_10515	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNA67_10525	COG1129	ABC transporter
FNA67_10555	COG1609	Transcriptional regulator
FNA67_10560	COG1522	sequence-specific DNA binding
FNA67_10590	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNA67_10595	COG4948	Mandelate Racemase Muconate Lactonizing
FNA67_10610	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNA67_10620	COG1137	ATPase activity
FNA67_10630	COG1012	belongs to the aldehyde dehydrogenase family
FNA67_10650	COG0183	Belongs to the thiolase family
FNA67_10655	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FNA67_10660	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FNA67_10665	COG3485	protocatechuate 3,4-dioxygenase
FNA67_10670	COG3485	protocatechuate 3,4-dioxygenase
FNA67_10675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNA67_10685	COG0583	DNA-binding transcription factor activity
FNA67_10690	COG0410	ABC transporter
FNA67_10695	COG0411	ABC transporter
FNA67_10710	COG0683	leucine binding
FNA67_10740	COG0084	hydrolase, TatD family'
FNA67_10755	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FNA67_10760	COG1686	Belongs to the peptidase S11 family
FNA67_10775	COG3956	TIGRFAM MazG family protein
FNA67_10780	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FNA67_10790	COG2204	response regulator
FNA67_10795	COG5000	phosphorelay sensor kinase activity
FNA67_10800	COG2204	response regulator
FNA67_10805	COG3852	Histidine kinase
FNA67_10810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FNA67_10815	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FNA67_10815	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FNA67_10820	COG1058	Belongs to the CinA family
FNA67_10820	COG1546	Belongs to the CinA family
FNA67_10830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FNA67_10840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNA67_10850	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNA67_10855	COG0022	dehydrogenase e1 component
FNA67_10855	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNA67_10860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FNA67_10880	COG0148	phosphopyruvate hydratase activity
FNA67_10895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FNA67_10935	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FNA67_10950	COG0024	Methionine aminopeptidase
FNA67_10955	COG0166	Belongs to the GPI family
FNA67_10960	COG0343	queuine tRNA-ribosyltransferase activity
FNA67_10970	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FNA67_10975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNA67_10980	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FNA67_10985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FNA67_11005	COG0587	DNA-directed DNA polymerase activity
FNA67_11010	COG1136	(ABC) transporter
FNA67_11020	COG0442	prolyl-tRNA aminoacylation
FNA67_11025	COG2264	protein methyltransferase activity
FNA67_11045	COG1007	ATP synthesis coupled electron transport
FNA67_11060	COG0713	ATP synthesis coupled electron transport
FNA67_11070	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNA67_11075	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FNA67_11095	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FNA67_11100	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
FNA67_11110	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNA67_11120	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FNA67_11145	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_11150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA67_11155	COG1879	ABC-type sugar transport system periplasmic component
FNA67_11170	COG1132	(ABC) transporter
FNA67_11175	COG1132	(ABC) transporter
FNA67_11210	COG0776	regulation of translation
FNA67_11225	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_11235	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNA67_11240	COG0372	Belongs to the citrate synthase family
FNA67_11255	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FNA67_11260	COG0740	serine-type endopeptidase activity
FNA67_11270	COG2124	cytochrome p450
FNA67_11285	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FNA67_11285	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FNA67_11300	COG0347	Belongs to the P(II) protein family
FNA67_11305	COG0174	glutamine synthetase
FNA67_11315	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FNA67_11320	COG1733	regulation of RNA biosynthetic process
FNA67_11340	COG0629	single-stranded DNA binding
FNA67_11345	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNA67_11355	COG0625	glutathione transferase activity
FNA67_11360	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
FNA67_11410	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FNA67_11415	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FNA67_11420	COG0805	protein transport
FNA67_11425	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FNA67_11435	COG3842	ATPase activity
FNA67_11440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FNA67_11445	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FNA67_11460	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FNA67_11465	COG0316	Belongs to the HesB IscA family
FNA67_11485	COG0129	dihydroxy-acid dehydratase activity
FNA67_11495	COG0525	valine-tRNA ligase activity
FNA67_11510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FNA67_11525	COG3842	ATPase activity
FNA67_11530	COG0395	ABC-type sugar transport system, permease component
FNA67_11565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNA67_11575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNA67_11580	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FNA67_11600	COG1999	signal sequence binding
FNA67_11635	COG0625	glutathione transferase activity
FNA67_11640	COG3135	benzoate transporter
FNA67_11645	COG0746	molybdenum cofactor guanylyltransferase activity
FNA67_11675	COG2274	protein secretion by the type I secretion system
FNA67_11685	COG1271	oxidase subunit
FNA67_11690	COG1294	oxidase, subunit
FNA67_11700	COG0175	sulfate reduction
FNA67_11705	COG0415	Belongs to the DNA photolyase family
FNA67_11710	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FNA67_11715	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNA67_11720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNA67_11725	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA67_11730	COG1126	abc transporter atp-binding protein
FNA67_11735	COG0765	amino acid transport
FNA67_11740	COG4597	amino acid ABC transporter
FNA67_11745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA67_11750	COG0626	cystathionine gamma-synthase activity
FNA67_11755	COG0671	phosphoesterase, PA-phosphatase related
FNA67_11775	COG0673	inositol 2-dehydrogenase activity
FNA67_11795	COG3842	ATPase activity
FNA67_11810	COG1653	transport
FNA67_11815	COG1609	Transcriptional regulator
FNA67_11835	COG0187	DNA topoisomerase II activity
FNA67_11840	COG0513	Belongs to the DEAD box helicase family
FNA67_11845	COG3706	GGDEF domain
FNA67_11850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FNA67_11855	COG0316	Belongs to the HesB IscA family
FNA67_11865	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FNA67_11870	COG0719	Fe-S assembly protein
FNA67_11875	COG0396	ATPase activity
FNA67_11885	COG0719	Fe-S assembly protein
FNA67_11895	COG2945	thiolester hydrolase activity
FNA67_11900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FNA67_11910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FNA67_11915	COG0739	heme binding
FNA67_11925	COG0242	peptide deformylase activity
FNA67_11930	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
FNA67_11940	COG1530	ribonuclease E activity
FNA67_11955	COG0436	Aminotransferase
FNA67_11970	COG0511	ligase activity, forming carbon-carbon bonds
FNA67_11980	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FNA67_12015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNA67_12020	COG4325	translation initiation factor activity
FNA67_12030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FNA67_12035	COG1780	Probably involved in ribonucleotide reductase function
FNA67_12045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FNA67_12055	COG0640	Transcriptional regulator
FNA67_12070	COG3210	domain, Protein
FNA67_12070	COG2911	Protein conserved in bacteria
FNA67_12095	COG0395	ABC-type sugar transport system, permease component
FNA67_12100	COG1175	transmembrane transport
FNA67_12110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNA67_12115	COG0183	Belongs to the thiolase family
FNA67_12125	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNA67_12145	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_12150	COG2204	response regulator
FNA67_12170	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNA67_12175	COG1653	transport
FNA67_12195	COG1653	transport
FNA67_12205	COG0395	ABC-type sugar transport system, permease component
FNA67_12215	COG3842	ATPase activity
FNA67_12220	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FNA67_12245	COG0356	it plays a direct role in the translocation of protons across the membrane
FNA67_12270	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FNA67_12275	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNA67_12290	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_12300	COG4191	Histidine kinase
FNA67_12300	COG0784	Response regulator, receiver
FNA67_12305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FNA67_12310	COG0574	Belongs to the PEP-utilizing enzyme family
FNA67_12310	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FNA67_12315	COG0837	glucose binding
FNA67_12320	COG0517	IMP dehydrogenase activity
FNA67_12330	COG1830	Aldolase
FNA67_12395	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNA67_12410	COG1596	polysaccharide export
FNA67_12415	COG2273	Hydrolase Family 16
FNA67_12440	COG1215	transferase activity, transferring glycosyl groups
FNA67_12455	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNA67_12460	COG3206	protein involved in exopolysaccharide biosynthesis
FNA67_12460	COG0489	protein tyrosine kinase activity
FNA67_12465	COG1215	transferase activity, transferring glycosyl groups
FNA67_12480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FNA67_12480	COG0473	3-isopropylmalate dehydrogenase activity
FNA67_12485	COG0747	negative chemotaxis
FNA67_12495	COG4174	ABC transporter (Permease)
FNA67_12505	COG0444	Belongs to the ABC transporter superfamily
FNA67_12510	COG4608	Belongs to the ABC transporter superfamily
FNA67_12515	COG1414	Transcriptional regulator
FNA67_12520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNA67_12525	COG3971	2-oxopent-4-enoate hydratase activity
FNA67_12540	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
FNA67_12555	COG0659	secondary active sulfate transmembrane transporter activity
FNA67_12560	COG5001	Diguanylate cyclase
FNA67_12560	COG3300	MHYT domain
FNA67_12570	COG0395	ABC-type sugar transport system, permease component
FNA67_12575	COG1175	transmembrane transport
FNA67_12585	COG2188	Transcriptional regulator
FNA67_12610	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
FNA67_12630	COG0444	Belongs to the ABC transporter superfamily
FNA67_12635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_12640	COG0601	transmembrane transport
FNA67_12645	COG0747	negative chemotaxis
FNA67_12680	COG0246	Mannitol dehydrogenase
FNA67_12700	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNA67_12710	COG3842	ATPase activity
FNA67_12720	COG0483	inositol monophosphate 1-phosphatase activity
FNA67_12725	COG0671	phosphoesterase, PA-phosphatase related
FNA67_12740	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FNA67_12745	COG3416	Protein conserved in bacteria
FNA67_12755	COG1215	transferase activity, transferring glycosyl groups
FNA67_12760	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNA67_12765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FNA67_12775	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FNA67_12780	COG0281	malic enzyme
FNA67_12780	COG0280	phosphate acetyltransferase
FNA67_12785	COG2200	EAL domain
FNA67_12790	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FNA67_12795	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
FNA67_12805	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FNA67_12815	COG0628	permease
FNA67_12820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FNA67_12830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FNA67_12835	COG0456	acetyltransferase
FNA67_12850	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNA67_12870	COG3811	Belongs to the UPF0386 family
FNA67_12885	COG0154	amidase activity
FNA67_12895	COG0454	-acetyltransferase
FNA67_12900	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FNA67_12925	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FNA67_12935	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FNA67_12940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FNA67_12945	COG0758	DNA mediated transformation
FNA67_12955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FNA67_12955	COG1754	DNA topoisomerase type I activity
FNA67_12960	COG0557	exoribonuclease II activity
FNA67_12970	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FNA67_12975	COG3706	GGDEF domain
FNA67_12975	COG0745	RESPONSE REGULATOR receiver
FNA67_12990	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNA67_13015	COG0537	adenosine 5'-monophosphoramidase activity
FNA67_13045	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FNA67_13050	COG1686	Belongs to the peptidase S11 family
FNA67_13060	COG3706	GGDEF domain
FNA67_13065	COG1192	Involved in chromosome partitioning
FNA67_13075	COG0625	glutathione transferase activity
FNA67_13080	COG2239	Acts as a magnesium transporter
FNA67_13105	COG0386	Belongs to the glutathione peroxidase family
FNA67_13130	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FNA67_13135	COG0321	lipoyl(octanoyl) transferase activity
FNA67_13145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNA67_13150	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FNA67_13160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FNA67_13170	COG0546	phosphoglycolate phosphatase activity
FNA67_13180	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FNA67_13195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FNA67_13200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNA67_13215	COG0203	ribosomal protein L17
FNA67_13220	COG0202	RNA polymerase activity
FNA67_13225	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FNA67_13230	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FNA67_13235	COG0563	adenylate kinase activity
FNA67_13240	COG0201	protein transport
FNA67_13245	COG0200	Binds to the 23S rRNA
FNA67_13255	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FNA67_13260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FNA67_13265	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FNA67_13270	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FNA67_13275	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FNA67_13280	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FNA67_13285	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FNA67_13290	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FNA67_13295	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FNA67_13300	COG0255	Belongs to the universal ribosomal protein uL29 family
FNA67_13305	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FNA67_13310	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FNA67_13315	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FNA67_13325	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FNA67_13330	COG0089	rRNA binding
FNA67_13335	COG0088	Forms part of the polypeptide exit tunnel
FNA67_13340	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FNA67_13345	COG0051	transcription antitermination factor activity, RNA binding
FNA67_13350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FNA67_13355	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FNA67_13360	COG0049	tRNA binding
FNA67_13365	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FNA67_13375	COG4122	O-methyltransferase activity
FNA67_13380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FNA67_13385	COG0085	RNA polymerase activity
FNA67_13390	COG0222	ribosome binding
FNA67_13395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FNA67_13400	COG0081	regulation of translation
FNA67_13405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FNA67_13415	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FNA67_13420	COG0589	response to stress
FNA67_13455	COG2261	transglycosylase associated protein
FNA67_13490	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FNA67_13500	COG1671	Belongs to the UPF0178 family
FNA67_13515	COG4214	carbohydrate transport
FNA67_13520	COG4213	ABC transporter substrate-binding protein
FNA67_13525	COG1940	carbohydrate kinase activity
FNA67_13525	COG1846	Transcriptional regulator
FNA67_13530	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNA67_13570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FNA67_13595	COG0745	RESPONSE REGULATOR receiver
FNA67_13600	COG2205	protein histidine kinase activity
FNA67_13620	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FNA67_13625	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FNA67_13635	COG0302	gtp cyclohydrolase
FNA67_13640	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FNA67_13690	COG2267	carboxylic ester hydrolase activity
FNA67_13710	COG0454	-acetyltransferase
FNA67_13710	COG0456	acetyltransferase
FNA67_13720	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_13725	COG3265	gluconokinase activity
FNA67_13755	COG2814	Major facilitator Superfamily
FNA67_13760	COG0583	DNA-binding transcription factor activity
FNA67_13780	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
FNA67_13785	COG1546	Belongs to the CinA family
FNA67_13785	COG1058	Belongs to the CinA family
FNA67_13790	COG0024	Methionine aminopeptidase
FNA67_13795	COG2003	Belongs to the UPF0758 family
FNA67_13805	COG0785	Cytochrome C biogenesis protein
FNA67_13815	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FNA67_13835	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FNA67_13840	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNA67_13850	COG0047	phosphoribosylformylglycinamidine synthase activity
FNA67_13860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FNA67_13895	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FNA67_13905	COG2814	Major facilitator Superfamily
FNA67_13910	COG0483	inositol monophosphate 1-phosphatase activity
FNA67_13915	COG0037	tRNA processing
FNA67_13920	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FNA67_13925	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FNA67_13935	COG2814	Major facilitator Superfamily
FNA67_13940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FNA67_13975	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FNA67_13985	COG0693	protein deglycase activity
FNA67_13995	COG0538	isocitrate dehydrogenase activity
FNA67_14005	COG4221	oxidoreductase activity
FNA67_14030	COG0697	spore germination
FNA67_14035	COG0697	spore germination
FNA67_14040	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FNA67_14045	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FNA67_14055	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNA67_14080	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FNA67_14085	COG1684	flagellar biosynthetic protein fliR
FNA67_14090	COG1987	bacterial-type flagellum assembly
FNA67_14095	COG1677	Flagellar hook-basal body complex protein FliE
FNA67_14100	COG1558	bacterial-type flagellum-dependent cell motility
FNA67_14105	COG1815	bacterial-type flagellum-dependent cell motility
FNA67_14110	COG3190	flagellar
FNA67_14115	COG1338	Plays a role in the flagellum-specific transport system
FNA67_14145	COG4786	Flagellar basal body rod
FNA67_14150	COG4786	Flagellar basal body rod
FNA67_14160	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FNA67_14165	COG0625	glutathione transferase activity
FNA67_14170	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
FNA67_14180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FNA67_14190	COG1706	bacterial-type flagellum-dependent cell motility
FNA67_14210	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
FNA67_14215	COG5443	negative regulation of bacterial-type flagellum assembly
FNA67_14235	COG1749	Flagellar hook protein flgE
FNA67_14245	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FNA67_14255	COG3106	COG3106 Predicted ATPase
FNA67_14260	COG3768	UPF0283 membrane protein
FNA67_14270	COG1733	regulation of RNA biosynthetic process
FNA67_14285	COG0492	ferredoxin-NADP+ reductase activity
FNA67_14290	COG0175	sulfate reduction
FNA67_14295	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FNA67_14305	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FNA67_14305	COG1648	precorrin-2 dehydrogenase activity
FNA67_14310	COG0395	ABC-type sugar transport system, permease component
FNA67_14315	COG0633	Ferredoxin
FNA67_14365	COG0438	transferase activity, transferring glycosyl groups
FNA67_14380	COG1472	Belongs to the glycosyl hydrolase 3 family
FNA67_14390	COG2259	Doxx family
FNA67_14395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FNA67_14415	COG0861	Integral membrane protein TerC family
FNA67_14420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FNA67_14425	COG4174	ABC transporter (Permease)
FNA67_14430	COG4239	(ABC) transporter, permease
FNA67_14435	COG4172	Belongs to the ABC transporter superfamily
FNA67_14440	COG4166	transmembrane transport
FNA67_14450	COG0668	transmembrane transport
FNA67_14455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FNA67_14460	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNA67_14465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FNA67_14475	COG0384	phenazine biosynthesis protein PhzF
FNA67_14480	COG4702	Belongs to the UPF0303 family
FNA67_14490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FNA67_14495	COG1309	transcriptional regulator
FNA67_14505	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FNA67_14520	COG1278	Cold shock
FNA67_14525	COG2249	NAD(P)H dehydrogenase (quinone) activity
FNA67_14530	COG0640	Transcriptional regulator
FNA67_14560	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FNA67_14570	COG2814	Major facilitator Superfamily
FNA67_14595	COG0440	acetolactate synthase activity
FNA67_14600	COG0028	Belongs to the TPP enzyme family
FNA67_14620	COG1280	lysine exporter protein (LysE YggA)
FNA67_14630	COG5002	protein histidine kinase activity
FNA67_14635	COG0745	RESPONSE REGULATOR receiver
FNA67_14645	COG1278	Cold shock
FNA67_14670	COG0534	Mate efflux family protein
FNA67_14675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FNA67_14680	COG0560	Phosphoserine phosphatase
FNA67_14680	COG3830	Belongs to the UPF0237 family
FNA67_14690	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNA67_14695	COG0330	HflC and HflK could
FNA67_14700	COG0330	HflC and HflK could
FNA67_14710	COG0456	acetyltransferase
FNA67_14725	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FNA67_14755	COG0443	Heat shock 70 kDa protein
FNA67_14780	COG2186	Transcriptional regulator
FNA67_14795	COG2983	Belongs to the UPF0260 family
FNA67_14850	COG2264	protein methyltransferase activity
FNA67_14855	COG0006	proline dipeptidase activity
FNA67_14880	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNA67_14890	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FNA67_14900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FNA67_14910	COG0849	cell division
FNA67_14915	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FNA67_14920	COG1181	Belongs to the D-alanine--D-alanine ligase family
FNA67_14925	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FNA67_14930	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FNA67_14940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FNA67_14945	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FNA67_14950	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FNA67_14965	COG0275	rRNA processing
FNA67_14985	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FNA67_15015	COG0640	Transcriptional regulator
FNA67_15020	COG1785	Belongs to the alkaline phosphatase family
FNA67_15040	COG2962	Rard protein
FNA67_15050	COG2267	carboxylic ester hydrolase activity
FNA67_15055	COG4106	trans-aconitate 2-methyltransferase activity
FNA67_15060	COG0488	(ABC) transporter
FNA67_15090	COG1522	sequence-specific DNA binding
FNA67_15095	COG0686	Belongs to the AlaDH PNT family
FNA67_15140	COG0559	Belongs to the binding-protein-dependent transport system permease family
FNA67_15150	COG0411	ABC transporter
FNA67_15160	COG0829	nickel cation binding
FNA67_15165	COG0831	urea catabolic process
FNA67_15170	COG0832	Belongs to the urease beta subunit family
FNA67_15175	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
FNA67_15190	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNA67_15195	COG1523	belongs to the glycosyl hydrolase 13 family
FNA67_15200	COG0033	Phosphoglucomutase
FNA67_15205	COG0297	glycogen (starch) synthase activity
FNA67_15210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FNA67_15215	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FNA67_15220	COG0058	SHG alpha-glucan phosphorylase activity
FNA67_15225	COG0475	glutathione-regulated potassium exporter activity
FNA67_15225	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FNA67_15235	COG1957	nucleoside hydrolase
FNA67_15240	COG1280	lysine exporter protein (LysE YggA)
FNA67_15245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNA67_15250	COG2094	Belongs to the DNA glycosylase MPG family
FNA67_15255	COG1215	transferase activity, transferring glycosyl groups
FNA67_15275	COG2755	lipolytic protein G-D-S-L family
FNA67_15275	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FNA67_15280	COG3458	cephalosporin-C deacetylase activity
FNA67_15285	COG1132	(ABC) transporter
FNA67_15320	COG1609	Transcriptional regulator
FNA67_15325	COG1129	ABC transporter
FNA67_15330	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNA67_15335	COG1879	ABC-type sugar transport system periplasmic component
FNA67_15360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FNA67_15365	COG0471	metal ion transport
FNA67_15365	COG0490	domain, Protein
FNA67_15370	COG2195	Cleaves the N-terminal amino acid of tripeptides
FNA67_15375	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
FNA67_15395	COG1278	Cold shock
FNA67_15420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNA67_15425	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FNA67_15445	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FNA67_15455	COG3454	Phosphonate metabolism
FNA67_15465	COG3639	organic phosphonate transmembrane transporter activity
FNA67_15470	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
FNA67_15475	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FNA67_15485	COG4778	phosphonate C-P lyase system protein PhnL
FNA67_15490	COG4107	phosphonate C-P lyase system protein PhnK
FNA67_15495	COG3627	carbon phosphorus lyase activity
FNA67_15500	COG3626	phosphonate metabolism
FNA67_15505	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
FNA67_15510	COG3624	Phosphonate C-P lyase system protein PhnG
FNA67_15515	COG2188	Transcriptional regulator
FNA67_15520	COG1012	belongs to the aldehyde dehydrogenase family
FNA67_15540	COG0432	Pfam Uncharacterised protein family UPF0047
FNA67_15555	COG0640	Transcriptional regulator
FNA67_15565	COG2862	Uncharacterized protein family, UPF0114
FNA67_15600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNA67_15620	COG2814	Major facilitator Superfamily
FNA67_15630	COG0505	Belongs to the CarA family
FNA67_15640	COG2321	neutral zinc metallopeptidase
FNA67_15645	COG0737	Belongs to the 5'-nucleotidase family
FNA67_15650	COG1846	Transcriptional regulator
FNA67_15655	COG1764	response to oxidative stress
FNA67_15660	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FNA67_15670	COG2814	Major facilitator Superfamily
FNA67_15685	COG0656	L-ascorbic acid biosynthetic process
FNA67_15715	COG3706	GGDEF domain
FNA67_15725	COG1278	Cold shock
FNA67_15730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNA67_15735	COG0492	ferredoxin-NADP+ reductase activity
FNA67_15740	COG0583	DNA-binding transcription factor activity
FNA67_15750	COG0598	Magnesium transport protein CorA
FNA67_15780	COG0516	GMP reductase activity
FNA67_15780	COG0517	IMP dehydrogenase activity
FNA67_15795	COG0745	RESPONSE REGULATOR receiver
FNA67_15800	COG2205	protein histidine kinase activity
FNA67_15805	COG1435	thymidine kinase activity
FNA67_15810	COG1607	acyl-coa hydrolase
FNA67_15815	COG4941	Belongs to the sigma-70 factor family
FNA67_15850	COG2267	carboxylic ester hydrolase activity
FNA67_15870	COG0556	nucleotide-excision repair
FNA67_15915	COG5342	invasion associated locus B
FNA67_15925	COG0322	excinuclease ABC activity
FNA67_15930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FNA67_15935	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FNA67_15945	COG0314	molybdopterin synthase activity
FNA67_15955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FNA67_15960	COG1846	Transcriptional regulator
FNA67_15970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FNA67_15975	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FNA67_15995	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
FNA67_16015	COG3795	YCII-related domain
FNA67_16020	COG3795	YCII-related domain
FNA67_16025	COG3795	YCII-related domain
FNA67_16040	COG0193	aminoacyl-tRNA hydrolase activity
FNA67_16045	COG0012	GTP binding
FNA67_16080	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FNA67_16090	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FNA67_16095	COG2857	Cytochrome c1
FNA67_16095	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNA67_16100	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FNA67_16100	COG2857	Cytochrome c1
FNA67_16105	COG0723	plastoquinol--plastocyanin reductase activity
FNA67_16110	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FNA67_16145	COG0435	Glutathione S-transferase
FNA67_16150	COG2814	Major facilitator Superfamily
FNA67_16160	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FNA67_16180	COG1365	unkown
FNA67_16185	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FNA67_16205	COG0439	Biotin carboxylase
FNA67_16210	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FNA67_16215	COG0604	alcohol dehydrogenase
FNA67_16230	COG3300	MHYT domain
FNA67_16230	COG5001	Diguanylate cyclase
FNA67_16245	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_16250	COG1063	alcohol dehydrogenase
FNA67_16275	COG5001	Diguanylate cyclase
FNA67_16275	COG3300	MHYT domain
FNA67_16280	COG5001	Diguanylate cyclase
FNA67_16280	COG3300	MHYT domain
FNA67_16295	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FNA67_16300	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FNA67_16305	COG0402	S-adenosylhomocysteine deaminase activity
FNA67_16330	COG1129	ABC transporter
FNA67_16350	COG2351	hydroxyisourate hydrolase activity
FNA67_16360	COG0737	Belongs to the 5'-nucleotidase family
FNA67_16375	COG0640	Transcriptional regulator
FNA67_16390	COG4266	Belongs to the allantoicase family
FNA67_16395	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FNA67_16415	COG0513	Belongs to the DEAD box helicase family
FNA67_16420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FNA67_16445	COG2261	transglycosylase associated protein
FNA67_16450	COG0673	inositol 2-dehydrogenase activity
FNA67_16480	COG3693	PFAM glycoside hydrolase, family 10
FNA67_16480	COG2382	esterase
FNA67_16500	COG3842	ATPase activity
FNA67_16505	COG2897	thiosulfate sulfurtransferase activity
FNA67_16515	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FNA67_16520	COG4214	carbohydrate transport
FNA67_16525	COG1129	ABC transporter
FNA67_16530	COG4213	ABC transporter substrate-binding protein
FNA67_16545	COG1012	belongs to the aldehyde dehydrogenase family
FNA67_16550	COG1177	transmembrane transport
FNA67_16555	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNA67_16560	COG3842	ATPase activity
FNA67_16565	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNA67_16570	COG0583	DNA-binding transcription factor activity
FNA67_16600	COG3920	Histidine kinase
FNA67_16600	COG2202	Pas domain
FNA67_16635	COG0784	Response regulator, receiver
FNA67_16655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FNA67_16660	COG4215	(ABC) transporter
FNA67_16665	COG4160	amino acid transport
FNA67_16675	COG3300	MHYT domain
FNA67_16675	COG5001	Diguanylate cyclase
FNA67_16680	COG0156	8-amino-7-oxononanoate synthase activity
FNA67_16690	COG0784	Response regulator, receiver
FNA67_16690	COG5002	protein histidine kinase activity
FNA67_16700	COG2860	membrane
FNA67_16705	COG3842	ATPase activity
FNA67_16720	COG1653	transport
FNA67_16725	COG1609	Transcriptional regulator
FNA67_16730	COG2301	Belongs to the HpcH HpaI aldolase family
FNA67_16735	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FNA67_16745	COG1397	ADP-ribosylglycohydrolase
FNA67_16755	COG0395	ABC-type sugar transport system, permease component
FNA67_16760	COG4209	transmembrane transport
FNA67_16765	COG1609	Transcriptional regulator
FNA67_16775	COG2378	regulation of single-species biofilm formation
FNA67_16795	COG1957	nucleoside hydrolase
FNA67_16845	COG1131	(ABC) transporter
FNA67_16875	COG0583	DNA-binding transcription factor activity
FNA67_16890	COG0395	ABC-type sugar transport system, permease component
FNA67_16950	COG0395	ABC-type sugar transport system, permease component
FNA67_16955	COG1175	transmembrane transport
FNA67_16965	COG5265	(ABC) transporter
FNA67_17025	COG0387	Pfam Sodium calcium exchanger
FNA67_17045	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNA67_17055	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNA67_17070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNA67_17075	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_17080	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNA67_17085	COG0251	oxidation-reduction process
FNA67_17090	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
FNA67_17110	COG4608	Belongs to the ABC transporter superfamily
FNA67_17115	COG0444	Belongs to the ABC transporter superfamily
FNA67_17120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_17125	COG0601	transmembrane transport
FNA67_17130	COG4166	transmembrane transport
FNA67_17175	COG0523	cobalamin synthesis protein
FNA67_17210	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
FNA67_17215	COG2223	nitrite transmembrane transporter activity
FNA67_17220	COG1733	regulation of RNA biosynthetic process
FNA67_17230	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNA67_17235	COG3842	ATPase activity
FNA67_17240	COG0395	ABC-type sugar transport system, permease component
FNA67_17245	COG1175	transmembrane transport
FNA67_17265	COG1609	Transcriptional regulator
FNA67_17275	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNA67_17285	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNA67_17305	COG4608	Belongs to the ABC transporter superfamily
FNA67_17310	COG0444	Belongs to the ABC transporter superfamily
FNA67_17315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_17320	COG0601	transmembrane transport
FNA67_17330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FNA67_17335	COG0747	negative chemotaxis
FNA67_17350	COG0300	oxidoreductase activity
FNA67_17355	COG4948	Mandelate Racemase Muconate Lactonizing
FNA67_17360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNA67_17365	COG0395	ABC-type sugar transport system, permease component
FNA67_17370	COG1175	transmembrane transport
FNA67_17400	COG3734	2-keto-3-deoxy-galactonokinase
FNA67_17425	COG4453	Protein conserved in bacteria
FNA67_17430	COG3153	acetyltransferase
FNA67_17445	COG0625	glutathione transferase activity
FNA67_17450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNA67_17455	COG1595	DNA-templated transcription, initiation
FNA67_17460	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_17510	COG0346	lactoylglutathione lyase activity
FNA67_17515	COG3706	GGDEF domain
FNA67_17535	COG2304	oxidoreductase activity
FNA67_17540	COG1595	DNA-templated transcription, initiation
FNA67_17545	COG0482	sulfurtransferase activity
FNA67_17570	COG1766	The M ring may be actively involved in energy transduction
FNA67_17575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FNA67_17585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
FNA67_17590	COG2204	response regulator
FNA67_17600	COG2153	protein acetylation
FNA67_17605	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FNA67_17630	COG1157	protein secretion by the type III secretion system
FNA67_17645	COG1609	Transcriptional regulator
FNA67_17680	COG0564	pseudouridine synthase activity
FNA67_17685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FNA67_17690	COG3093	addiction module antidote protein HigA
FNA67_17710	COG4143	(ABC) transporter
FNA67_17730	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FNA67_17745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FNA67_17755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNA67_17775	COG1737	Transcriptional regulator
FNA67_17805	COG0444	Belongs to the ABC transporter superfamily
FNA67_17855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNA67_17865	COG0583	DNA-binding transcription factor activity
FNA67_17880	COG5342	invasion associated locus B
FNA67_17885	COG3214	Protein conserved in bacteria
FNA67_17900	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FNA67_17905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FNA67_17910	COG0037	tRNA processing
FNA67_17925	COG2885	chlorophyll binding
FNA67_17930	COG0823	Involved in the tonB-independent uptake of proteins
FNA67_17940	COG0848	biopolymer transport protein
FNA67_17950	COG0824	Thioesterase
FNA67_17960	COG2255	four-way junction helicase activity
FNA67_17965	COG0632	four-way junction helicase activity
FNA67_17970	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FNA67_17975	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FNA67_17995	COG1692	metallophosphoesterase
FNA67_18000	COG0217	transcriptional regulatory protein
FNA67_18005	COG5002	protein histidine kinase activity
FNA67_18005	COG5001	Diguanylate cyclase
FNA67_18005	COG3447	MASE1 domain protein
FNA67_18035	COG0126	phosphoglycerate kinase activity
FNA67_18040	COG3588	fructose-bisphosphate aldolase
FNA67_18055	COG0483	inositol monophosphate 1-phosphatase activity
FNA67_18075	COG1132	(ABC) transporter
FNA67_18080	COG0254	rRNA binding
FNA67_18130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FNA67_18135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FNA67_18150	COG0745	RESPONSE REGULATOR receiver
FNA67_18175	COG0789	Transcriptional regulator
FNA67_18180	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FNA67_18185	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FNA67_18190	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FNA67_18205	COG2204	response regulator
FNA67_18215	COG0257	Belongs to the bacterial ribosomal protein bL36 family
FNA67_18235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_18240	COG0601	transmembrane transport
FNA67_18245	COG4166	transmembrane transport
FNA67_18250	COG0183	Belongs to the thiolase family
FNA67_18255	COG1024	Enoyl-CoA hydratase
FNA67_18255	COG1250	3-hydroxyacyl-CoA dehydrogenase
FNA67_18265	COG0318	PFAM AMP-dependent synthetase and ligase
FNA67_18270	COG0789	Transcriptional regulator
FNA67_18275	COG0322	excinuclease ABC activity
FNA67_18300	COG0667	Aldo Keto reductase
FNA67_18305	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FNA67_18310	COG1643	Atp-dependent helicase
FNA67_18325	COG2203	Gaf domain
FNA67_18325	COG2199	diguanylate cyclase activity
FNA67_18365	COG0070	glutamate synthase
FNA67_18365	COG0069	glutamate synthase activity
FNA67_18365	COG0067	glutamate synthase
FNA67_18370	COG0625	glutathione transferase activity
FNA67_18400	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FNA67_18410	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNA67_18415	COG0330	HflC and HflK could
FNA67_18420	COG1585	Membrane protein implicated in regulation of membrane protease activity
FNA67_18425	COG1360	Flagellar Motor Protein
FNA67_18430	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FNA67_18440	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FNA67_18445	COG1914	H( )-stimulated, divalent metal cation uptake system
FNA67_18450	COG0210	DNA helicase
FNA67_18455	COG0708	Exodeoxyribonuclease III
FNA67_18470	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
FNA67_18485	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
FNA67_18490	COG0583	DNA-binding transcription factor activity
FNA67_18500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FNA67_18505	COG0800	Aldolase
FNA67_18520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FNA67_18535	COG2721	sulfolactate sulfo-lyase activity
FNA67_18540	COG1254	Belongs to the acylphosphatase family
FNA67_18545	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FNA67_18565	COG1396	sequence-specific DNA binding
FNA67_18600	COG1304	FMN binding
FNA67_18640	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FNA67_18645	COG0179	Fumarylacetoacetate (FAA) hydrolase
FNA67_18665	COG0251	oxidation-reduction process
FNA67_18670	COG0586	Pfam SNARE associated Golgi protein
FNA67_18675	COG0457	Tetratricopeptide repeat
FNA67_18690	COG1454	alcohol dehydrogenase
FNA67_18695	COG0400	carboxylic ester hydrolase activity
FNA67_18700	COG0346	lactoylglutathione lyase activity
FNA67_18705	COG2375	cellular response to nickel ion
FNA67_18720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FNA67_18745	COG2183	response to ionizing radiation
FNA67_18750	COG3264	Mechanosensitive ion channel
FNA67_18750	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FNA67_18755	COG3938	Belongs to the proline racemase family
FNA67_18765	COG1609	Transcriptional regulator
FNA67_18770	COG0747	negative chemotaxis
FNA67_18775	COG0601	transmembrane transport
FNA67_18780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_18790	COG4608	Belongs to the ABC transporter superfamily
FNA67_18815	COG1802	Transcriptional regulator
FNA67_18820	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
FNA67_18830	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
FNA67_18835	COG1312	Catalyzes the dehydration of D-mannonate
FNA67_18885	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FNA67_18920	COG0739	heme binding
FNA67_18925	COG0477	Major facilitator Superfamily
FNA67_18935	COG0542	response to heat
FNA67_18945	COG2890	protein-(glutamine-N5) methyltransferase activity
FNA67_18950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FNA67_18960	COG0527	aspartate kinase activity
FNA67_18965	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FNA67_18990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FNA67_18995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FNA67_19005	COG2226	methyltransferase
FNA67_19015	COG0494	nUDIX hydrolase
FNA67_19020	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FNA67_19035	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FNA67_19040	COG0653	protein targeting
FNA67_19045	COG3034	peptidoglycan biosynthetic process
FNA67_19050	COG0825	malonyl-CoA metabolic process
FNA67_19055	COG4974	Belongs to the 'phage' integrase family
FNA67_19065	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FNA67_19070	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FNA67_19095	COG2226	methyltransferase
FNA67_19110	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
FNA67_19115	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FNA67_19145	COG1329	Transcriptional regulator
FNA67_19150	COG4783	chaperone-mediated protein folding
FNA67_19170	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNA67_19175	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FNA67_19180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNA67_19185	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FNA67_19190	COG1120	ATPase activity
FNA67_19205	COG2885	chlorophyll binding
FNA67_19235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNA67_19240	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FNA67_19245	COG0444	Belongs to the ABC transporter superfamily
FNA67_19250	COG4608	Belongs to the ABC transporter superfamily
FNA67_19255	COG3395	kinase activity
FNA67_19260	COG2186	Transcriptional regulator
FNA67_19275	COG4166	transmembrane transport
FNA67_19280	COG0601	transmembrane transport
FNA67_19285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FNA67_19290	COG1454	alcohol dehydrogenase
FNA67_19310	COG0071	Belongs to the small heat shock protein (HSP20) family
FNA67_19315	COG1686	Belongs to the peptidase S11 family
FNA67_19320	COG2378	regulation of single-species biofilm formation
FNA67_19335	COG1733	regulation of RNA biosynthetic process
FNA67_19345	COG0534	Mate efflux family protein
FNA67_19420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FNA67_19440	COG2096	Adenosyltransferase
FNA67_19460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNA67_19465	COG0165	Argininosuccinate lyase
FNA67_19470	COG0019	diaminopimelate decarboxylase activity
FNA67_19475	COG1346	cytolysis
FNA67_19495	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FNA67_19500	COG4208	sulfate ABC transporter
FNA67_19505	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FNA67_19510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FNA67_19515	COG1959	2 iron, 2 sulfur cluster binding
FNA67_19535	COG4948	Mandelate Racemase Muconate Lactonizing
FNA67_19540	COG1028	Short-chain dehydrogenase reductase Sdr
FNA67_19555	COG0395	ABC-type sugar transport system, permease component
FNA67_19560	COG1175	transmembrane transport
FNA67_19580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FNA67_19615	COG3254	rhamnose metabolic process
FNA67_19630	COG2186	Transcriptional regulator
FNA67_19635	COG1846	Transcriptional regulator
FNA67_19655	COG0840	transmembrane signaling receptor activity
FNA67_19675	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNA67_19680	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
FNA67_19690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
FNA67_19710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FNA67_19715	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FNA67_19720	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FNA67_19730	COG0799	negative regulation of ribosome biogenesis
FNA67_19735	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FNA67_19740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FNA67_19745	COG0277	FAD linked oxidase domain protein
FNA67_19750	COG1695	Transcriptional regulator
FNA67_19755	COG0335	large ribosomal subunit rRNA binding
FNA67_19770	COG1999	signal sequence binding
FNA67_19775	COG0336	Belongs to the RNA methyltransferase TrmD family
FNA67_19780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FNA67_19785	COG0228	four-way junction DNA binding
FNA67_19790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FNA67_19810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FNA67_19815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNA67_19820	COG0552	protein localization to endoplasmic reticulum
FNA67_19825	COG2917	probably involved in intracellular septation
FNA67_19835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FNA67_19845	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNA67_19850	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FNA67_19855	COG4133	protoheme IX ABC transporter activity
FNA67_19860	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FNA67_19885	COG0670	Belongs to the BI1 family
FNA67_19890	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
FNA67_19905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FNA67_19920	COG0793	Belongs to the peptidase S41A family
FNA67_19925	COG2861	carbohydrate metabolic process
FNA67_19930	COG0494	nUDIX hydrolase
FNA67_19940	COG1794	racemase activity, acting on amino acids and derivatives
FNA67_19950	COG0840	transmembrane signaling receptor activity
FNA67_19960	COG2201	protein-glutamate methylesterase activity
FNA67_19965	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FNA67_19970	COG0840	transmembrane signaling receptor activity
FNA67_19975	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
FNA67_19985	COG0835	chemotaxis
FNA67_19990	COG0643	Histidine kinase
FNA67_19990	COG2198	Histidine kinase
FNA67_20005	COG1024	Enoyl-CoA hydratase
FNA67_20030	COG0842	Transport permease protein
FNA67_20035	COG1131	(ABC) transporter
FNA67_20045	COG1309	transcriptional regulator
FNA67_20055	COG1309	transcriptional regulator
FNA67_20075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA67_20080	COG2313	pseudouridylate synthase activity
FNA67_20085	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
FNA67_20090	COG3842	ATPase activity
FNA67_20095	COG1176	ABC-type spermidine putrescine transport system, permease component I
FNA67_20100	COG1177	transmembrane transport
FNA67_20110	COG0697	spore germination
FNA67_20115	COG0673	inositol 2-dehydrogenase activity
FNA67_20120	COG1879	ABC-type sugar transport system periplasmic component
FNA67_20125	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNA67_20140	COG0673	inositol 2-dehydrogenase activity
FNA67_20145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA67_20150	COG3962	Belongs to the TPP enzyme family
FNA67_20155	COG1082	Xylose isomerase domain protein TIM barrel
FNA67_20165	COG3718	enzyme involved in inositol metabolism
FNA67_20170	COG1956	GAF domain-containing protein
FNA67_20190	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FNA67_20195	COG1280	lysine exporter protein (LysE YggA)
FNA67_20205	COG0137	argininosuccinate synthase activity
FNA67_20210	COG5001	Diguanylate cyclase
FNA67_20220	COG0586	Pfam SNARE associated Golgi protein
FNA67_20225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FNA67_20235	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FNA67_20240	COG0287	Prephenate dehydrogenase
FNA67_20250	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
FNA67_20270	COG2884	Cell division ATP-binding protein ftsE
FNA67_20280	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FNA67_20285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FNA67_20300	COG2258	MOSC domain
FNA67_20310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FNA67_20325	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
FNA67_20335	COG3300	MHYT domain
FNA67_20335	COG5001	Diguanylate cyclase
FNA67_20365	COG0410	ABC transporter
FNA67_20380	COG0840	transmembrane signaling receptor activity
FNA67_20380	COG0840	transmembrane signaling receptor activity
FNA67_20385	COG0840	transmembrane signaling receptor activity
FNA67_20390	COG0840	transmembrane signaling receptor activity
FNA67_20395	COG0840	transmembrane signaling receptor activity
FNA67_20400	COG0840	transmembrane signaling receptor activity
FNA67_20405	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FNA67_20410	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FNA67_20415	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FNA67_20420	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FNA67_20425	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FNA67_20435	COG4974	Belongs to the 'phage' integrase family
FNA67_20440	COG0697	spore germination
FNA67_20445	COG3300	MHYT domain
FNA67_20445	COG5001	Diguanylate cyclase
FNA67_20465	COG0395	ABC-type sugar transport system, permease component
FNA67_20480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FNA67_20520	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
FNA67_20525	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FNA67_20530	COG2350	Protein conserved in bacteria
FNA67_20550	COG0501	Belongs to the peptidase M48B family
FNA67_20555	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FNA67_20555	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
FNA67_20575	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FNA67_20600	COG1872	DUF167
FNA67_20605	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FNA67_20630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FNA67_20665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FNA67_20670	COG0587	DNA-directed DNA polymerase activity
FNA67_20675	COG2154	pterin-4-alpha-carbinolamine dehydratase
FNA67_20685	COG1280	lysine exporter protein (LysE YggA)
FNA67_20695	COG0508	dehydrogenase complex catalyzes the overall conversion of
FNA67_20705	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FNA67_20710	COG0662	Cupin 2, conserved barrel domain protein
FNA67_20715	COG0045	succinate-CoA ligase (ADP-forming) activity
FNA67_20720	COG0039	L-malate dehydrogenase activity
FNA67_20725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FNA67_20775	COG0494	nUDIX hydrolase
FNA67_20785	COG0288	reversible hydration of carbon dioxide
FNA67_20805	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FNA67_20810	COG2081	HI0933 family
FNA67_20825	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FNA67_20830	COG0473	3-isopropylmalate dehydrogenase activity
FNA67_20835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FNA67_20845	COG0251	oxidation-reduction process
FNA67_20850	COG0066	3-isopropylmalate dehydratase activity
FNA67_20855	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FNA67_20865	COG0813	purine-nucleoside phosphorylase activity
FNA67_20880	COG1172	Belongs to the binding-protein-dependent transport system permease family
FNA67_20885	COG4941	Belongs to the sigma-70 factor family
FNA67_20895	COG3795	YCII-related domain
FNA67_20915	COG3795	YCII-related domain
FNA67_20935	COG3118	belongs to the thioredoxin family
FNA67_20940	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FNA67_20945	COG2835	tetraacyldisaccharide 4'-kinase activity
FNA67_20950	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FNA67_20955	COG0347	Belongs to the P(II) protein family
FNA67_20960	COG0004	ammonium transporteR
FNA67_20995	COG0745	RESPONSE REGULATOR receiver
FNA67_21000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FNA67_21015	COG1466	dna polymerase III delta subunit
FNA67_21020	COG1475	DNA binding
FNA67_21025	COG1192	Involved in chromosome partitioning
FNA67_21030	COG0357	Ribosomal RNA small subunit methyltransferase G
FNA67_21040	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FNA67_21045	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
FNA67_21055	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FNA67_21060	COG0424	maF-like protein
FNA67_21065	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FNA67_21070	COG0237	dephospho-CoA kinase activity
FNA67_21075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FNA67_21080	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FNA67_21090	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
FNA67_21105	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FNA67_21110	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FNA67_21120	COG0107	imidazoleglycerol-phosphate synthase activity
FNA67_21125	COG0140	phosphoribosyl-ATP diphosphatase activity
FNA67_21130	COG1072	(Pantothenic acid kinase))
FNA67_21150	COG0284	orotidine-5'-phosphate decarboxylase activity
FNA67_21155	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FNA67_21160	COG0588	phosphoglycerate mutase activity
FNA67_21165	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FNA67_21185	COG1309	transcriptional regulator
FNA67_21190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FNA67_21195	COG0484	heat shock protein binding
FNA67_21205	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FNA67_21230	COG1335	isochorismatase
FNA67_21235	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FNA67_21240	COG1420	regulation of RNA biosynthetic process
FNA67_21245	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FNA67_21250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FNA67_21255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FNA67_21270	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
FNA67_21275	COG0792	nuclease activity
FNA67_21280	COG0189	ligase activity
FNA67_21285	COG2095	MarC family integral membrane protein
FNA67_21295	COG0606	chelatase, subunit chli
FNA67_21325	COG0402	S-adenosylhomocysteine deaminase activity
FNA67_21340	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FNA67_21345	COG1609	Transcriptional regulator
FNA67_21355	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FNA67_21385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FNA67_21390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNA67_21395	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FNA67_21410	COG2852	Protein conserved in bacteria
FNA67_21430	COG1309	transcriptional regulator
FNA67_21450	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FNA67_21455	COG1959	2 iron, 2 sulfur cluster binding
FNA67_21465	COG0493	'glutamate synthase
FNA67_21470	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FNA67_21480	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FNA67_21485	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FNA67_21490	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FNA67_21500	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FNA67_21505	COG1702	phosphate starvation-inducible protein PhoH
FNA67_21510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FNA67_21525	COG0456	acetyltransferase
FNA67_21525	COG0454	-acetyltransferase
FNA67_21530	COG1214	PFAM Peptidase M22, glycoprotease
FNA67_21535	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
FNA67_21550	COG0180	Tryptophanyl-tRNA synthetase
FNA67_21560	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FNA67_21565	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FNA67_21570	COG3507	Belongs to the glycosyl hydrolase 43 family
FNA67_21575	COG2115	Belongs to the xylose isomerase family
FNA67_21580	COG1070	Carbohydrate kinase
FNA67_21595	COG0667	Aldo Keto reductase
FNA67_21600	COG0779	Required for maturation of 30S ribosomal subunits
FNA67_21605	COG0195	Participates in both transcription termination and antitermination
FNA67_21605	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FNA67_21615	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FNA67_21620	COG1376	ErfK ybiS ycfS ynhG family protein
FNA67_21625	COG0740	serine-type endopeptidase activity
FNA67_21640	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FNA67_21645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FNA67_21655	COG3920	Histidine kinase
FNA67_21670	COG0640	Transcriptional regulator
FNA67_21700	COG0477	Major facilitator Superfamily
FNA67_21720	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FNA67_21740	COG0756	dUTP diphosphatase activity
FNA67_21750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FNA67_21755	COG2226	methyltransferase
FNA67_21760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FNA67_21765	COG0268	Binds directly to 16S ribosomal RNA