locus-tag	class	description
AZF00_00010	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AZF00_00015	ENOG4105E2X	shikimate dehydrogenase
AZF00_00025	ENOG4108Z0R	Transferase
AZF00_00030	ENOG4105DGW	oligopeptidase A
AZF00_00050	ENOG4105EG6	Saccharopine dehydrogenase
AZF00_00065	ENOG4105EUB	pirin domain protein
AZF00_00070	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AZF00_00075	ENOG4105CWB	LysR family transcriptional Regulator
AZF00_00085	ENOG4107R73	Mate efflux family protein
AZF00_00090	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AZF00_00125	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
AZF00_00130	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AZF00_00140	ENOG4105FAV	ABC, transporter
AZF00_00145	ENOG4105FDK	ABC transporter
AZF00_00150	ENOG4105MYN	Zinc uptake regulation protein
AZF00_00155	ENOG4105NXV	High-affinity zinc uptake system protein
AZF00_00170	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AZF00_00180	ENOG4106RE7	Cytochrome
AZF00_00200	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AZF00_00205	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AZF00_00210	ENOG4107SEY	Conserved Protein
AZF00_00215	ENOG4105MPD	Cytochrome
AZF00_00230	ENOG4108JPW	Aminotransferase
AZF00_00235	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
AZF00_00240	ENOG4105CZK	Aspartate kinase
AZF00_00270	ENOG4107QJR	hflk protein
AZF00_00275	ENOG4105EPW	hflc protein
AZF00_00285	ENOG4106HNH	Acyl-transferase
AZF00_00290	ENOG4105GRZ	Ycii-related protein
AZF00_00295	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
AZF00_00300	ENOG4108YYC	ycei family
AZF00_00305	ENOG4105CPD	ethanolamine ammonia-lyase
AZF00_00310	ENOG4107FQ9	ethanolamine ammonia-lyase
AZF00_00315	ENOG4105BZU	Histidine kinase
AZF00_00325	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AZF00_00355	ENOG410719E	cytochrome p450
AZF00_00370	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AZF00_00380	ENOG41067MG	lrgb family
AZF00_00390	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AZF00_00395	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
AZF00_00405	ENOG4105EZR	dyp-type peroxidase family protein
AZF00_00420	ENOG4107TPY	serine threonine protein kinase
AZF00_00435	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AZF00_00460	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AZF00_00480	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AZF00_00490	ENOG4105VN1	Heat shock protein
AZF00_00495	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AZF00_00515	ENOG4105BZM	domain protein
AZF00_00545	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
AZF00_00555	ENOG4105VEJ	Heat shock protein
AZF00_00560	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
AZF00_00575	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AZF00_00580	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AZF00_00610	ENOG4105EGS	Mechanosensitive ion channel
AZF00_00615	ENOG4107QPN	acyl-Coa dehydrogenase
AZF00_00625	ENOG4105C01	Dihydroxy-acid dehydratase
AZF00_00635	ENOG4105E09	nadh pyrophosphatase
AZF00_00640	ENOG4105CHR	reductase
AZF00_00650	ENOG4105CSA	Coproporphyrinogen iii oxidase
AZF00_00655	ENOG4105K6T	rare lipoprotein A
AZF00_00660	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AZF00_00665	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
AZF00_00670	ENOG4105K63	Thioredoxin
AZF00_00675	ENOG4105C9X	ppx gppa phosphatase
AZF00_00680	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
AZF00_00685	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AZF00_00690	ENOG4105DFG	type I secretion outer membrane protein
AZF00_00695	ENOG4108SX3	cytoplasmic protein
AZF00_00700	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
AZF00_00705	ENOG4105IPS	esterase
AZF00_00710	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AZF00_00725	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AZF00_00755	ENOG4105C4R	Atp-dependent dna helicase
AZF00_00760	ENOG4105C0P	Mg chelatase subunit ChlI
AZF00_00795	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AZF00_00815	ENOG4105W0Z	cytoplasmic protein
AZF00_00820	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AZF00_00825	ENOG4108YZ9	Urea amidohydrolase subunit gamma
AZF00_00830	ENOG4105KI2	Urea amidohydrolase subunit beta
AZF00_00835	ENOG4105CQM	Urea amidohydrolase subunit alpha
AZF00_00840	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
AZF00_00845	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
AZF00_00850	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
AZF00_00865	ENOG4105C32	Amino acid ABC transporter (Permease)
AZF00_00875	ENOG4105C0Z	ABC transporter
AZF00_00880	ENOG4108IV0	ABC, transporter
AZF00_00885	ENOG4105DS1	cytochrome b561
AZF00_00890	ENOG4108YYC	ycei family
AZF00_00905	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
AZF00_00920	ENOG4108YZA	Nitrogen regulatory protein pii
AZF00_00955	ENOG4108YZA	Nitrogen regulatory protein pii
AZF00_00970	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AZF00_00985	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AZF00_00990	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AZF00_01000	ENOG4105XQ6	frataxin-like protein
AZF00_01010	ENOG4107T0K	Adenylate cyclase
AZF00_01020	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AZF00_01025	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AZF00_01035	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AZF00_01040	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AZF00_01060	ENOG4105D75	Capsular exopolysaccharide family
AZF00_01065	ENOG4105DAY	polysaccharide export protein
AZF00_01090	ENOG4107QPH	glycogen) synthase
AZF00_01100	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AZF00_01120	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AZF00_01125	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AZF00_01140	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AZF00_01160	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AZF00_01180	ENOG4105D75	Capsular exopolysaccharide family
AZF00_01185	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AZF00_01190	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AZF00_01205	ENOG4105CMR	udp-glucose 4-epimerase
AZF00_01235	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AZF00_01260	ENOG4105DYW	oxidoreductase
AZF00_01265	ENOG4107ZSV	Receptor
AZF00_01275	ENOG4105D6S	protein involved in catabolism of external DNA
AZF00_01280	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AZF00_01290	ENOG4105FBW	Monooxygenase
AZF00_01295	ENOG4107RX3	Mg2 transporter protein cora family protein
AZF00_01300	ENOG4105KT7	mgtC SapB transporter
AZF00_01305	ENOG4105SYT	Methylenetetrahydrofolate reductase
AZF00_01310	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AZF00_01320	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AZF00_01330	ENOG4107ZF2	Phosphatase
AZF00_01335	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AZF00_01345	ENOG4105BZA	Phosphoglycerate kinase
AZF00_01350	ENOG4105D2N	Aldolase
AZF00_01370	ENOG4105BZU	Histidine kinase
AZF00_01385	ENOG4105BZU	Histidine kinase
AZF00_01490	ENOG4108KU3	Integrase
AZF00_01505	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AZF00_01510	ENOG4105CEN	a g-specific adenine glycosylase
AZF00_01520	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AZF00_01525	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AZF00_01530	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AZF00_01535	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AZF00_01540	ENOG4105CN1	protease
AZF00_01555	ENOG4107YZP	Rhodanese domain protein
AZF00_01560	ENOG4105VW4	glutaredoxin 3
AZF00_01565	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AZF00_01570	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AZF00_01575	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AZF00_01580	ENOG4105CUX	Signal transduction histidine kinase
AZF00_01590	ENOG4105C5F	glutamine synthetase
AZF00_01595	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AZF00_01610	ENOG4105C8J	)-transporter
AZF00_01625	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AZF00_01635	ENOG410630P	Transcriptional regulator
AZF00_01665	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
AZF00_01700	ENOG4105CIR	epoxide hydrolase
AZF00_01705	ENOG4107RGH	Aldehyde dehydrogenase
AZF00_01710	ENOG4108MIW	Induces the synthesis of acid phosphatase (AppA) and several other polypeptides (such as AppBC) during the deceleration phase of growth. It also acts as a transcriptional repressor for one group of proteins that are synthesized preferentially in exponential growth and for one group synthesized only in the stationary phase. Also involved in the stabilization of the sigma stress factor RpoS during stress conditions
AZF00_01715	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_01720	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AZF00_01740	ENOG4108UKI	Enoyl-CoA hydratase
AZF00_01750	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AZF00_01760	ENOG4107QX3	carboxylase
AZF00_01765	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_01770	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
AZF00_01785	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AZF00_01805	ENOG4108IPT	Naphthoate synthase
AZF00_01820	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
AZF00_01825	ENOG4105DYW	oxidoreductase
AZF00_01830	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
AZF00_01840	ENOG4107RET	Isocitrate lyase
AZF00_01845	ENOG4107QP3	malate synthase g
AZF00_01855	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AZF00_01865	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
AZF00_01870	ENOG4105C3Q	Glycosyl transferase, family 2
AZF00_01875	ENOG4107QW3	Sucrose phosphorylase
AZF00_01880	ENOG4105CSU	acyl-Coa dehydrogenase
AZF00_01885	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AZF00_01890	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AZF00_01895	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AZF00_01900	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AZF00_01910	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AZF00_01915	ENOG4105DJ0	Poly(A) Polymerase
AZF00_01920	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AZF00_01925	ENOG4105BZU	Histidine kinase
AZF00_01930	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AZF00_01935	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AZF00_01965	ENOG4105D52	delta-aminolevulinic acid dehydratase
AZF00_01970	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AZF00_01975	ENOG4108YXA	Membrane
AZF00_01980	ENOG4105CMQ	Chloride channel
AZF00_01985	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AZF00_01990	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AZF00_01995	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AZF00_02000	ENOG4105DR5	peptidase
AZF00_02005	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AZF00_02035	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AZF00_02070	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AZF00_02080	ENOG4105PM1	preprotein translocase subunit SecE
AZF00_02085	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AZF00_02090	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AZF00_02095	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AZF00_02100	ENOG4108VZM	50s ribosomal protein L10
AZF00_02105	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AZF00_02110	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AZF00_02115	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AZF00_02120	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AZF00_02125	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AZF00_02130	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AZF00_02135	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AZF00_02140	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AZF00_02145	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AZF00_02150	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AZF00_02155	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AZF00_02160	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AZF00_02165	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AZF00_02170	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AZF00_02175	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AZF00_02180	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AZF00_02185	ENOG41083MP	50s ribosomal protein l29
AZF00_02190	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AZF00_02195	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AZF00_02200	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AZF00_02205	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AZF00_02210	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AZF00_02215	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AZF00_02220	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AZF00_02225	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AZF00_02230	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AZF00_02235	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AZF00_02240	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AZF00_02245	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AZF00_02250	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AZF00_02255	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AZF00_02260	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AZF00_02265	ENOG4108ZT0	50S ribosomal protein l17
AZF00_02270	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AZF00_02275	ENOG4107RDB	Major Facilitator
AZF00_02280	ENOG4108UUM	single-stranded DNA-binding protein
AZF00_02290	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AZF00_02295	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AZF00_02305	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AZF00_02310	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AZF00_02320	ENOG4107QP8	phosphohexose isomerase
AZF00_02325	ENOG4105EAH	synthase
AZF00_02330	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AZF00_02340	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AZF00_02345	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AZF00_02350	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AZF00_02355	ENOG41080IJ	Diacylglycerol kinase
AZF00_02360	ENOG4105D1S	lipid A biosynthesis
AZF00_02395	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AZF00_02405	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AZF00_02430	ENOG4107S6X	Glycosyl transferase, family 2
AZF00_02445	ENOG4108UT6	Transferase hexapeptide repeat containing protein
AZF00_02455	ENOG4105CHH	sulfate transporter
AZF00_02475	ENOG4105VPX	protein, conserved in bacteria
AZF00_02480	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
AZF00_02490	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AZF00_02495	ENOG4105DNH	Major Facilitator
AZF00_02505	ENOG4106A3M	Cytochrome p-450
AZF00_02525	ENOG4105CHR	reductase
AZF00_02550	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AZF00_02605	ENOG4105F95	Monooxygenase
AZF00_02610	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
AZF00_02635	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_02640	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AZF00_02645	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_02650	ENOG4105E39	Enoyl-CoA hydratase
AZF00_02655	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AZF00_02670	ENOG4105VTR	Integrase
AZF00_02775	ENOG4108Z0R	Transferase
AZF00_02785	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_02795	ENOG4105C26	Dehydrogenase
AZF00_02825	ENOG4107SP2	The ortholog in A.thaliana is involved in photosystem II (PSII) assembly, but knockout of the corresponding gene in Synechoccus PCC 7002 has no effect on PSII activity
AZF00_02845	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AZF00_02850	ENOG4105DXM	phenylacetic acid degradation protein
AZF00_02855	ENOG4108UKI	Enoyl-CoA hydratase
AZF00_02860	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_02865	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
AZF00_02870	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
AZF00_02875	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
AZF00_02880	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
AZF00_02885	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
AZF00_02890	ENOG4108ZJI	phenylacetic acid degradation protein
AZF00_02895	ENOG4108Z40	Transcriptional regulator
AZF00_02905	ENOG4105ECQ	AraC Family Transcriptional Regulator
AZF00_02910	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AZF00_02920	ENOG4105VCQ	rubredoxin
AZF00_02935	ENOG4105EQR	Transposase IS116 IS110 IS902
AZF00_02945	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AZF00_02950	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AZF00_02975	ENOG4105VTR	Integrase
AZF00_03000	ENOG4105ENA	helicase
AZF00_03045	ENOG4106HFR	
AZF00_03090	ENOG4105CMM	transposase
AZF00_03105	ENOG4105CMM	transposase
AZF00_03120	ENOG4107WZZ	SMC domain protein
AZF00_03130	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AZF00_03195	ENOG4105EGS	Mechanosensitive ion channel
AZF00_03220	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AZF00_03245	ENOG4105DGI	Alkaline phosphatase
AZF00_03275	ENOG4108HFV	
AZF00_03280	ENOG4107XZC	Restriction modification system DNA (Specificity
AZF00_03285	ENOG4105CVR	type I restriction-modification system
AZF00_03290	ENOG4107R3N	Filamentation induced by cAMP protein fic
AZF00_03295	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
AZF00_03335	ENOG4105C9X	ppx gppa phosphatase
AZF00_03355	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AZF00_03365	ENOG4108Z1B	Cyclase dehydrase
AZF00_03370	ENOG4105VDB	UPF0125 protein
AZF00_03380	ENOG41090R7	Ferric uptake
AZF00_03385	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AZF00_03390	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AZF00_03395	ENOG4105CFG	Acts as a chaperone (By similarity)
AZF00_03400	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AZF00_03405	ENOG4107S2Z	UPF0761 membrane protein
AZF00_03410	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AZF00_03415	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AZF00_03420	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AZF00_03425	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AZF00_03430	ENOG4105HBR	Rna-binding protein
AZF00_03435	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AZF00_03445	ENOG4105EEI	dihydropteroate synthase
AZF00_03450	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AZF00_03460	ENOG4107EJC	Preprotein translocase subunit SecG
AZF00_03470	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AZF00_03475	ENOG4105CHV	Transcription elongation factor NusA
AZF00_03480	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AZF00_03485	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AZF00_03490	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AZF00_03495	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AZF00_03500	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AZF00_03515	ENOG4107XM9	(LipO)protein
AZF00_03520	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AZF00_03535	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AZF00_03545	ENOG4105EAC	phosphoserine phosphatase
AZF00_03560	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AZF00_03565	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AZF00_03570	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AZF00_03580	ENOG4105KHC	sulfurtransferase
AZF00_03585	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AZF00_03590	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AZF00_03595	ENOG4107SUD	Esterase
AZF00_03600	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AZF00_03610	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AZF00_03615	ENOG4105K8N	protein family UPF0079, ATPase
AZF00_03620	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AZF00_03625	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AZF00_03630	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AZF00_03635	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AZF00_03640	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AZF00_03645	ENOG4107QJR	hflk protein
AZF00_03650	ENOG4105EPW	hflc protein
AZF00_03660	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
AZF00_03695	ENOG4105C26	Dehydrogenase
AZF00_03715	ENOG4108X3M	OsmC Ohr family protein
AZF00_03725	ENOG4105CEY	Amp-dependent synthetase and ligase
AZF00_03740	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
AZF00_03760	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
AZF00_03770	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_03775	ENOG4105CYC	Transferase
AZF00_03795	ENOG4105D05	Receptor
AZF00_03815	ENOG4107Z7P	Ferredoxin
AZF00_03820	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
AZF00_03840	ENOG4105K56	Transcriptional regulator
AZF00_03850	ENOG41090TK	Short-chain dehydrogenase reductase Sdr
AZF00_03855	ENOG4105VQD	rieske 2fe-2S domain-containing protein
AZF00_03860	ENOG4108JNI	Alpha beta hydrolase
AZF00_03870	ENOG4105DF3	Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity)
AZF00_03880	ENOG4105FUY	alpha subunit
AZF00_03885	ENOG4105KRG	Aromatic-ring-hydroxylating dioxygenase beta subunit
AZF00_03910	ENOG4105CCU	oxidase (Subunit III)
AZF00_03920	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AZF00_03930	ENOG4108J2R	molybdopterin oxidoreductase
AZF00_03940	ENOG4105EQH	reductase
AZF00_03945	ENOG4105BZU	Histidine kinase
AZF00_03950	ENOG4108RF4	Tetr family transcriptional regulator
AZF00_03975	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_03985	ENOG4108UKI	Enoyl-CoA hydratase
AZF00_03990	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
AZF00_04000	ENOG4105C26	Dehydrogenase
AZF00_04010	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AZF00_04025	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_04030	ENOG4108KB2	LysR family Transcriptional regulator
AZF00_04035	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AZF00_04040	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_04055	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
AZF00_04080	ENOG4108IPT	Naphthoate synthase
AZF00_04090	ENOG4107ZSV	Receptor
AZF00_04100	ENOG4108M7F	enoyl-CoA hydratase isomerase
AZF00_04115	ENOG4108IJ2	phosphate acetyltransferase
AZF00_04130	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AZF00_04135	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_04160	ENOG4105DZG	Dehydrogenase
AZF00_04180	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AZF00_04185	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AZF00_04190	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AZF00_04195	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AZF00_04205	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AZF00_04210	ENOG4105CDU	Replicative dna helicase
AZF00_04225	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AZF00_04235	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AZF00_04240	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AZF00_04250	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AZF00_04265	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AZF00_04270	ENOG4108JQC	penicillin-binding protein 1A
AZF00_04295	ENOG4105E4G	Type IV pilus
AZF00_04305	ENOG4105D49	3-dehydroquinate synthase
AZF00_04310	ENOG4105CBC	glutamate synthase
AZF00_04315	ENOG4105BZ8	glutamate synthase
AZF00_04340	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AZF00_04345	ENOG4105ERG	peptidase m48, ste24p
AZF00_04350	ENOG4105D7W	serine acetyltransferase
AZF00_04355	ENOG4108UW5	maltose o-acetyltransferase
AZF00_04370	ENOG4105DA5	(ABC) transporter
AZF00_04375	ENOG4105E3A	(ABC) transporter
AZF00_04380	ENOG4105NXH	GreA GreB family elongation factor
AZF00_04400	ENOG4105E27	serine threonine protein kinase
AZF00_04405	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AZF00_04410	ENOG4105E0C	molybdate abc transporter
AZF00_04415	ENOG4105MJ2	Competence protein
AZF00_04425	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AZF00_04450	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AZF00_04455	ENOG4105CSU	acyl-Coa dehydrogenase
AZF00_04460	ENOG4105CSU	acyl-Coa dehydrogenase
AZF00_04480	ENOG4105HUJ	glyoxalase bleomycin resistance protein dioxygenase
AZF00_04495	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AZF00_04500	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AZF00_04505	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AZF00_04510	ENOG41063TF	transcriptional regulator (AraC
AZF00_04515	ENOG4108EKI	Dehydrogenase
AZF00_04520	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_04525	ENOG4105E39	Enoyl-CoA hydratase
AZF00_04530	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AZF00_04535	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AZF00_04540	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AZF00_04550	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
AZF00_04555	ENOG4105CYN	Serine protein kinase
AZF00_04560	ENOG4106AKX	UPF0229 protein
AZF00_04565	ENOG4105ED1	spovr family
AZF00_04570	ENOG4105CGU	Enoyl-CoA hydratase
AZF00_04585	ENOG4105BZU	Histidine kinase
AZF00_04590	ENOG4105BZU	Histidine kinase
AZF00_04600	ENOG4105D3G	Pseudouridine synthase
AZF00_04610	ENOG4106A3M	Cytochrome p-450
AZF00_04615	ENOG4105BZU	Histidine kinase
AZF00_04620	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AZF00_04655	ENOG4105CGU	Enoyl-CoA hydratase
AZF00_04660	ENOG4108IG5	Transcriptional regulator
AZF00_04665	ENOG4105C4R	Atp-dependent dna helicase
AZF00_04680	ENOG4105DEN	Luciferase family
AZF00_04695	ENOG4107IFA	Lipase (EC 3.1.1.3)
AZF00_04720	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AZF00_04740	ENOG41061WM	D-Alanyl-D-Alanine
AZF00_04780	ENOG4105E5H	Transposase
AZF00_04795	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
AZF00_04800	ENOG4108CAF	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway (By similarity)
AZF00_04805	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
AZF00_04810	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AZF00_04830	ENOG4108V0P	LemA family
AZF00_04840	ENOG4105C6T	cysteine synthase
AZF00_04850	ENOG4105K6V	RNA polymerase
AZF00_04860	ENOG4107ZSV	Receptor
AZF00_04870	ENOG4105BZU	Histidine kinase
AZF00_04880	ENOG4105EJ9	Membrane
AZF00_04885	ENOG4108YZN	class I peptide chain release factor
AZF00_04890	ENOG4105CRQ	synthase (Component I)
AZF00_04895	ENOG4105DDQ	anthranilate synthase
AZF00_04900	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AZF00_04905	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AZF00_04910	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
AZF00_04915	ENOG4108UKZ	OsmC family
AZF00_04925	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
AZF00_04930	ENOG4105BZU	Histidine kinase
AZF00_04935	ENOG4105C12	Phosphoribosylglycinamide synthetase
AZF00_04940	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AZF00_04945	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AZF00_04950	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AZF00_04960	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AZF00_04965	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AZF00_04970	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AZF00_04975	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AZF00_04980	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AZF00_05000	ENOG4105K63	Thioredoxin
AZF00_05010	ENOG4105BZ4	penicillin-binding protein
AZF00_05015	ENOG4105DKW	ABC transporter
AZF00_05025	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AZF00_05035	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AZF00_05065	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AZF00_05075	ENOG4108W15	Protein of unknown function (DUF1456)
AZF00_05080	ENOG4105DZB	Electron transport complex
AZF00_05085	ENOG4108UQQ	Electron transport complex
AZF00_05090	ENOG4105D6A	Electron transport complex
AZF00_05100	ENOG4108R3D	Electron transport complex
AZF00_05105	ENOG4105DGN	Electron transport complex
AZF00_05110	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AZF00_05120	ENOG4105DHP	deoxycytidine triphosphate deaminase
AZF00_05130	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AZF00_05135	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AZF00_05145	ENOG4105C02	permease
AZF00_05155	ENOG4108WHA	ompa motb domain protein
AZF00_05160	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AZF00_05165	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AZF00_05170	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AZF00_05175	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
AZF00_05190	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AZF00_05195	ENOG4105BZU	Histidine kinase
AZF00_05200	ENOG4107EFR	Flavocytochrome c
AZF00_05205	ENOG4107ZSV	Receptor
AZF00_05210	ENOG4105RKW	reductase (By
AZF00_05215	ENOG4107QI1	Mate efflux family protein
AZF00_05225	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AZF00_05230	ENOG4105DCF	alanine dehydrogenase
AZF00_05245	ENOG4105CEY	Amp-dependent synthetase and ligase
AZF00_05255	ENOG4105EW9	transcriptional regulator AsnC family
AZF00_05270	ENOG4107R1I	NAD-dependent malic enzyme
AZF00_05285	ENOG4105EA8	2-Nitropropane dioxygenase
AZF00_05290	ENOG4105E39	Enoyl-CoA hydratase
AZF00_05295	ENOG4105CC9	acyl-Coa dehydrogenase
AZF00_05305	ENOG4105F2C	Acetyl-CoA acetyltransferase
AZF00_05325	ENOG4105CC9	acyl-Coa dehydrogenase
AZF00_05335	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_05375	ENOG4108VKG	metal-dependent hydrolase
AZF00_05380	ENOG4105CNG	UPF0061 protein
AZF00_05385	ENOG4105E55	glycerol-3-phosphate acyltransferase
AZF00_05395	ENOG4107ZSV	Receptor
AZF00_05400	ENOG4105D9U	N-acetyltransferase
AZF00_05410	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AZF00_05420	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
AZF00_05425	ENOG4105QUC	reductase
AZF00_05430	ENOG41081F0	Precorrin-8x methylmutase
AZF00_05435	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
AZF00_05440	ENOG4105DVK	Precorrin-2 c20-methyltransferase
AZF00_05445	ENOG4108P62	biosynthesis protein (CbiG)
AZF00_05455	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
AZF00_05460	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
AZF00_05480	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AZF00_05485	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AZF00_05520	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
AZF00_05545	ENOG4105EQD	regulatoR
AZF00_05560	ENOG4105BZU	Histidine kinase
AZF00_05565	ENOG4105KK4	UPF0060 membrane protein
AZF00_05580	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AZF00_05600	ENOG4105C9M	aspartyl-trna synthetase
AZF00_05605	ENOG4105CDY	transcriptional regulatory protein
AZF00_05610	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AZF00_05615	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AZF00_05620	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AZF00_05625	ENOG4107YD3	Thioesterase
AZF00_05630	ENOG4105E02	MotA TolQ exbB proton channel
AZF00_05635	ENOG4105M8F	Biopolymer transport protein exbD tolR
AZF00_05645	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AZF00_05650	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AZF00_05655	ENOG4105UFD	tol-pal system protein YbgF
AZF00_05660	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AZF00_05665	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AZF00_05680	ENOG4105C01	Dihydroxy-acid dehydratase
AZF00_05685	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AZF00_05700	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_05705	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_05750	ENOG4105D05	Receptor
AZF00_05760	ENOG4105VRT	cytoplasmic protein
AZF00_05765	ENOG4105EJ2	Transcriptional regulator
AZF00_05785	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AZF00_05800	ENOG4105E39	Enoyl-CoA hydratase
AZF00_05815	ENOG4105EA8	2-Nitropropane dioxygenase
AZF00_05820	ENOG4106AXJ	AraC family transcriptional regulator
AZF00_05845	ENOG4108UHU	Aldolase
AZF00_05850	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AZF00_05855	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AZF00_05880	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AZF00_05885	ENOG4108ZC9	flagellar basal-body rod protein flgc
AZF00_05890	ENOG4105W00	Flagellar hook capping protein
AZF00_05895	ENOG4105BZE	flagellar hook protein, FlgE
AZF00_05900	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AZF00_05905	ENOG4105CGA	flagellar basal-body rod protein FlgG
AZF00_05910	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AZF00_05915	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AZF00_05920	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AZF00_05925	ENOG4105E1Q	flagellar hook-associated protein
AZF00_05930	ENOG4105DTJ	flagellar hook-associated protein
AZF00_05935	ENOG4105D7B	Flagellar biosynthesis protein flha
AZF00_05940	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AZF00_05950	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AZF00_05960	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AZF00_05965	ENOG4105EW9	transcriptional regulator AsnC family
AZF00_05990	ENOG4105CEP	NADH dehydrogenase
AZF00_05995	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AZF00_06010	ENOG4105CSU	acyl-Coa dehydrogenase
AZF00_06035	ENOG4105F2C	Acetyl-CoA acetyltransferase
AZF00_06040	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_06060	ENOG4107ZSV	Receptor
AZF00_06095	ENOG4105X7H	acyl-CoA dehydrogenase
AZF00_06100	ENOG4108KC2	acyl-Coa dehydrogenase
AZF00_06115	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_06120	ENOG4105X7H	acyl-CoA dehydrogenase
AZF00_06170	ENOG4105ENR	peptidase, M24
AZF00_06175	ENOG4108JPW	Aminotransferase
AZF00_06180	ENOG4105CH2	amidohydrolase
AZF00_06190	ENOG4107RK0	Sucrose phosphorylase
AZF00_06195	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
AZF00_06205	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
AZF00_06215	ENOG4108ESX	Receptor
AZF00_06225	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AZF00_06230	ENOG4105CW7	secretion protein, HlyD family
AZF00_06245	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AZF00_06265	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AZF00_06280	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AZF00_06295	ENOG4108RG0	uracil-dna glycosylase
AZF00_06300	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AZF00_06315	ENOG4108RRZ	Transcription elongation factor GreB
AZF00_06325	ENOG4105W49	UPF0434 protein
AZF00_06330	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AZF00_06335	ENOG4105CFH	Aspartokinase
AZF00_06340	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AZF00_06350	ENOG410624X	efflux transporter, rnd family, mfp subunit
AZF00_06355	ENOG4105BZS	acriflavin resistance protein
AZF00_06360	ENOG4105NBK	UPF0345 protein
AZF00_06365	ENOG4105CDV	Ompa motb domain protein
AZF00_06375	ENOG4108R6G	acetyltransferase
AZF00_06380	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AZF00_06430	ENOG4105M6W	Crispr-associated protein, Csy3 family
AZF00_06445	ENOG4105CIR	epoxide hydrolase
AZF00_06450	ENOG4105CSU	acyl-Coa dehydrogenase
AZF00_06460	ENOG4105KF3	Short-chain dehydrogenase reductase Sdr
AZF00_06465	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_06470	ENOG4105C0B	DNA polymerase III (alpha subunit)
AZF00_06475	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
AZF00_06500	ENOG4105UBK	short-chain dehydrogenase reductase
AZF00_06505	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AZF00_06510	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AZF00_06515	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AZF00_06520	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AZF00_06525	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AZF00_06530	ENOG4105CQC	Prephenate dehydratase
AZF00_06535	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AZF00_06540	ENOG4105EVN	Prephenate dehydrogenase
AZF00_06545	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AZF00_06550	ENOG4105CAT	Cytidine monophosphate kinase
AZF00_06555	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AZF00_06560	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AZF00_06570	ENOG4105CFV	Tetratricopeptide repeat protein
AZF00_06575	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AZF00_06600	ENOG4106W5V	Membrane
AZF00_06610	ENOG4105VTR	Integrase
AZF00_06620	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AZF00_06645	ENOG4105C22	threonyL-tRNA synthetase
AZF00_06650	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AZF00_06655	ENOG41082NX	50s ribosomal protein l35
AZF00_06660	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AZF00_06665	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AZF00_06670	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AZF00_06675	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AZF00_06705	ENOG4105M2Z	protein tyrosine serine phosphatase
AZF00_06710	ENOG4105BZU	Histidine kinase
AZF00_06715	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AZF00_06725	ENOG4105D00	flagellar biosynthetic protein flhB
AZF00_06735	ENOG4108V06	Glutathione peroxidase
AZF00_06740	ENOG4105K56	Transcriptional regulator
AZF00_06745	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AZF00_06750	ENOG4105W8H	transhydrogenase (subunit alpha
AZF00_06755	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
AZF00_06760	ENOG4105BZU	Histidine kinase
AZF00_06790	ENOG4105T16	Transcriptional regulator (AraC family)
AZF00_06795	ENOG4107RX2	synthase
AZF00_06810	ENOG41069NU	Nitroreductase
AZF00_06815	ENOG4105E39	Enoyl-CoA hydratase
AZF00_06835	ENOG4105C0A	alcohol dehydrogenase
AZF00_06840	ENOG4105EUZ	Beta-lactamase domain protein
AZF00_06850	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AZF00_06890	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AZF00_06900	ENOG4105VUT	cytoplasmic protein
AZF00_06910	ENOG4105CD8	aminopeptidase N
AZF00_06915	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AZF00_06920	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AZF00_06925	ENOG41081FY	multiple antibiotic resistance (MarC)-related
AZF00_06940	ENOG4105BZU	Histidine kinase
AZF00_06945	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AZF00_06950	ENOG4105BZU	Histidine kinase
AZF00_06955	ENOG4105BZU	Histidine kinase
AZF00_06980	ENOG4105FBT	Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (By similarity)
AZF00_07005	ENOG4107QHF	type ii secretion system protein e
AZF00_07010	ENOG4105D7Q	type ii secretion system
AZF00_07015	ENOG4108VAU	general secretion pathway protein G
AZF00_07025	ENOG4105X5Z	General secretion pathway protein I
AZF00_07030	ENOG4108WWZ	General secretion pathway protein J
AZF00_07055	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_07060	ENOG4105CC9	acyl-Coa dehydrogenase
AZF00_07065	ENOG4105CHR	reductase
AZF00_07070	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AZF00_07075	ENOG4105BZU	Histidine kinase
AZF00_07095	ENOG4105V9V	Short-chain dehydrogenase reductase Sdr
AZF00_07105	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AZF00_07150	ENOG4105Y75	tpr repeat protein
AZF00_07160	ENOG4108IYU	L-aspartate oxidase
AZF00_07165	ENOG4105EMN	RNA polymerase sigma factor
AZF00_07170	ENOG41069E1	anti sigma-E protein RseA
AZF00_07175	ENOG4105VQK	sigma E regulatory protein, MucB RseB
AZF00_07180	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
AZF00_07185	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AZF00_07190	ENOG4105C3F	Signal peptidase i
AZF00_07200	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AZF00_07205	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AZF00_07215	ENOG4105BZU	Histidine kinase
AZF00_07220	ENOG4105C6T	cysteine synthase
AZF00_07225	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AZF00_07230	ENOG4105DXN	mazG family
AZF00_07240	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AZF00_07245	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AZF00_07255	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AZF00_07260	ENOG41072GX	Peptidase M22 Glycoprotease
AZF00_07265	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AZF00_07270	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
AZF00_07275	ENOG4105DFM	M18 family aminopeptidase
AZF00_07280	ENOG4108UKI	Enoyl-CoA hydratase
AZF00_07295	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AZF00_07330	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AZF00_07340	ENOG4108Z0R	Transferase
AZF00_07350	ENOG4108JU6	CBS domain protein
AZF00_07360	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AZF00_07365	ENOG4105K5M	30s ribosomal protein S16
AZF00_07370	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AZF00_07375	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AZF00_07380	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AZF00_07385	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AZF00_07390	ENOG4105T95	Thiol disulfide interChange protein
AZF00_07395	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AZF00_07400	ENOG4108ETH	Formylglycinamide ribotide synthetase
AZF00_07405	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AZF00_07410	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AZF00_07415	ENOG4105ECY	inositol monophosphatase
AZF00_07420	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AZF00_07425	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AZF00_07430	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AZF00_07435	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AZF00_07440	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
AZF00_07445	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
AZF00_07450	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AZF00_07455	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AZF00_07465	ENOG4108K5P	(LipO)protein
AZF00_07470	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AZF00_07475	ENOG4108Z4U	Ferredoxin
AZF00_07490	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AZF00_07495	ENOG4105CZX	twitching motility protein
AZF00_07555	ENOG4105Y3E	Modulates RecA activity (By similarity)
AZF00_07575	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AZF00_07580	ENOG4108J59	Extracellular solute-binding protein, family 5
AZF00_07585	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AZF00_07590	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AZF00_07595	ENOG4105C3U	ABC transporter
AZF00_07600	ENOG4108JQ7	(ABC) transporter
AZF00_07610	ENOG4105CEY	Amp-dependent synthetase and ligase
AZF00_07615	ENOG4105CQ7	ATP-dependent helicase
AZF00_07625	ENOG4105E18	UPF0276 protein
AZF00_07635	ENOG410903C	(LipO)protein
AZF00_07655	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
AZF00_07660	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AZF00_07665	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AZF00_07680	ENOG4105C0H	protease
AZF00_07695	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AZF00_07700	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AZF00_07705	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AZF00_07715	ENOG4105VNG	YcgL domain-containing protein
AZF00_07720	ENOG4108ZZ3	UPF0260 protein
AZF00_07730	ENOG4105IDI	abc transporter atp-binding protein
AZF00_07750	ENOG4105D9P	serine threonine protein kinase
AZF00_07755	ENOG4105C6T	cysteine synthase
AZF00_07770	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AZF00_07775	ENOG4105BZU	Histidine kinase
AZF00_07785	ENOG4105QVC	MOSC domain-containing protein
AZF00_07790	ENOG4107SC1	transglycosylase
AZF00_07795	ENOG4105C5H	ABC transporter
AZF00_07800	ENOG41081QV	Universal stress protein
AZF00_07815	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AZF00_07835	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AZF00_07845	ENOG4105D64	Mechanosensitive ion channel
AZF00_07850	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AZF00_07860	ENOG4108JA2	transcriptioN-repair coupling factor
AZF00_07870	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AZF00_07875	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AZF00_07880	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AZF00_07890	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
AZF00_07900	ENOG4105CJ2	(LipO)protein
AZF00_07910	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AZF00_07920	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AZF00_07935	ENOG4108EC8	DNA internalization-related competence protein ComEC
AZF00_07945	ENOG4109015	Biopolymer transport protein exbD tolR
AZF00_07950	ENOG4105BZ1	(ABC) transporter
AZF00_07955	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AZF00_07970	ENOG4105D4A	Cell wall formation (By similarity)
AZF00_07985	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AZF00_08025	ENOG4105C5X	domain protein
AZF00_08030	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AZF00_08035	ENOG4105M00	molybdopterin converting factor, subunit 1
AZF00_08040	ENOG4108ZAF	Molybdopterin
AZF00_08050	ENOG4108JW7	Maf-like protein
AZF00_08055	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AZF00_08060	ENOG4105CGY	Dna recombination protein
AZF00_08065	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AZF00_08085	ENOG4105CGK	Exodeoxyribonuclease III
AZF00_08090	ENOG4105VIE	preprotein translocase, subunit YajC
AZF00_08095	ENOG4105K6H	D-cysteine desulfhydrase
AZF00_08100	ENOG4105BZG	amino acid carrier protein
AZF00_08105	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
AZF00_08120	ENOG4107R11	Transcriptional regulator
AZF00_08125	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
AZF00_08130	ENOG4105CRQ	synthase (Component I)
AZF00_08135	ENOG4105D8K	carboxyl transferase
AZF00_08140	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AZF00_08155	ENOG4105DJT	lAO AO transport system ATPase
AZF00_08170	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
AZF00_08180	ENOG4105CKW	Inner membrane protein yedI
AZF00_08215	ENOG4105F95	Monooxygenase
AZF00_08230	ENOG4105EEF	Alkane 1-monooxygenase
AZF00_08240	ENOG4105E39	Enoyl-CoA hydratase
AZF00_08245	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AZF00_08250	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AZF00_08280	ENOG4105EZE	Cupin 4 family protein
AZF00_08285	ENOG4107QTF	adenylosuccinate lyase
AZF00_08290	ENOG41075W9	High frequency lysogenization protein HflD homolog
AZF00_08305	ENOG4108R99	pseudouridine synthase
AZF00_08315	ENOG4105VEQ	Cold shock protein
AZF00_08320	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AZF00_08325	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AZF00_08330	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AZF00_08335	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
AZF00_08340	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AZF00_08345	ENOG4105C3M	thioredoxin reductase
AZF00_08350	ENOG4105CNU	cell division protein FtsK
AZF00_08355	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AZF00_08360	ENOG4105D1H	recombination factor protein RarA
AZF00_08365	ENOG4105WMR	Protein CrcB homolog
AZF00_08370	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AZF00_08375	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AZF00_08380	ENOG4105DC8	reductase
AZF00_08385	ENOG4105CN1	protease
AZF00_08390	ENOG4105X1P	Steroid delta-isomerase
AZF00_08395	ENOG4105CEY	Amp-dependent synthetase and ligase
AZF00_08420	ENOG410903C	(LipO)protein
AZF00_08455	ENOG4108Z6Z	Transcriptional regulator
AZF00_08460	ENOG4105C59	p-type ATPase
AZF00_08465	ENOG4105C59	p-type ATPase
AZF00_08480	ENOG4107Z6A	sulfate abc transporter permease
AZF00_08485	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
AZF00_08490	ENOG4108JUA	Transcriptional regulator
AZF00_08525	ENOG4105PGM	cation diffusion facilitator family transporter
AZF00_08545	ENOG4108I6A	alcohol dehydrogenase
AZF00_08575	ENOG4105C5X	domain protein
AZF00_08580	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AZF00_08635	ENOG4105W1Y	Transcriptional regulator
AZF00_08660	ENOG4105PGM	cation diffusion facilitator family transporter
AZF00_08665	ENOG4105KK4	UPF0060 membrane protein
AZF00_08740	ENOG4105E3B	Multicopper oxidase
AZF00_08745	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AZF00_08780	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AZF00_08805	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
AZF00_08815	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AZF00_08820	ENOG4105DHQ	Histidine kinase
AZF00_08825	ENOG41080IJ	Diacylglycerol kinase
AZF00_08830	ENOG4105DIJ	Phosphoethanolamine transferase
AZF00_08880	ENOG4108IJF	Heavy metal efflux pump, CzcA
AZF00_08945	ENOG4105GR3	Histidine kinase
AZF00_08950	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AZF00_08980	ENOG4105W1Y	Transcriptional regulator
AZF00_08985	ENOG4105PGM	cation diffusion facilitator family transporter
AZF00_09075	ENOG4105C4R	Atp-dependent dna helicase
AZF00_09100	ENOG4105F5W	AtP-binding protein
AZF00_09105	ENOG4105D70	Integrase catalytic subunit
AZF00_09140	ENOG4105KJM	monovalent cation h antiporter subunit g
AZF00_09150	ENOG4105MKQ	Monovalent cation H antiporter subunit C
AZF00_09155	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AZF00_09160	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AZF00_09170	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AZF00_09180	ENOG4105ERU	peptidase
AZF00_09195	ENOG4108JDX	DNA polymerase iii, epsilon subunit
AZF00_09200	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AZF00_09205	ENOG4105D1A	Methyltransferase
AZF00_09210	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AZF00_09215	ENOG4105E9H	Lytic Murein transglycosylase
AZF00_09220	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
AZF00_09225	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
AZF00_09230	ENOG4108J59	Extracellular solute-binding protein, family 5
AZF00_09240	ENOG4108JQ7	(ABC) transporter
AZF00_09245	ENOG4105EQD	regulatoR
AZF00_09250	ENOG4105M2Z	protein tyrosine serine phosphatase
AZF00_09255	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AZF00_09265	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AZF00_09275	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AZF00_09280	ENOG4105X23	Endonuclease Exonuclease phosphatase
AZF00_09295	ENOG4107RUK	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins (By similarity)
AZF00_09300	ENOG4105C3R	Methionine synthase
AZF00_09325	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AZF00_09330	ENOG4105WH1	Two component transcriptional regulator luxr family
AZF00_09335	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AZF00_09345	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AZF00_09355	ENOG4105C10	Electron transfer flavoprotein
AZF00_09360	ENOG4105BZJ	Electron transfer flavoprotein
AZF00_09365	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AZF00_09370	ENOG4105CHR	reductase
AZF00_09395	ENOG4105F5W	AtP-binding protein
AZF00_09400	ENOG4105D70	Integrase catalytic subunit
AZF00_09430	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AZF00_09435	ENOG4105K70	DNA-binding protein
AZF00_09440	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AZF00_09445	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AZF00_09450	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AZF00_09455	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AZF00_09465	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_09470	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AZF00_09475	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
AZF00_09480	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AZF00_09485	ENOG4105F8V	Hydrolase, tatD family
AZF00_09495	ENOG4107QRG	dna polymerase iii
AZF00_09500	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AZF00_09505	ENOG4105HHA	aminodeoxychorismate lyase
AZF00_09510	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
AZF00_09515	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AZF00_09520	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AZF00_09525	ENOG4105CHR	reductase
AZF00_09530	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AZF00_09535	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AZF00_09540	ENOG4105VGS	50s ribosomal protein l32
AZF00_09550	ENOG4108UHJ	MAF-like protein
AZF00_09555	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AZF00_09560	ENOG4105EI2	Pseudouridine synthase
AZF00_09565	ENOG4105C03	ribonuclease
AZF00_09575	ENOG4105D58	Diguanylate phosphodiesterase
AZF00_09580	ENOG4108MN8	Membrane
AZF00_09585	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
AZF00_09600	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
AZF00_09605	ENOG4107QYG	anthranilate phosphoribosyltransferase
AZF00_09610	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
AZF00_09615	ENOG4105KZX	Pterin carbinolamine dehydratase
AZF00_09645	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AZF00_09650	ENOG4105E3A	(ABC) transporter
AZF00_09655	ENOG4105DA5	(ABC) transporter
AZF00_09680	ENOG4105E0X	reductase
AZF00_09685	ENOG4105CHM	Aminotransferase
AZF00_09690	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AZF00_09700	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AZF00_09705	ENOG4108BPE	-transporting atpase
AZF00_09725	ENOG4105YP7	UPF0270 protein
AZF00_09755	ENOG4105D8G	Major Facilitator superfamily
AZF00_09760	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AZF00_09765	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AZF00_09770	ENOG4105EUJ	GTP cyclohydrolase i
AZF00_09785	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AZF00_09790	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AZF00_09795	ENOG4105CSU	acyl-Coa dehydrogenase
AZF00_09805	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AZF00_09810	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AZF00_09815	ENOG4107QN2	dihydrolipoyl dehydrogenase
AZF00_09820	ENOG4105C7S	Dehydrogenase
AZF00_09825	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
AZF00_09830	ENOG4105E33	succinate dehydrogenase
AZF00_09835	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AZF00_09840	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
AZF00_09845	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
AZF00_09850	ENOG4105BZN	citrate synthase
AZF00_09875	ENOG4108DQR	cina-like protein
AZF00_09895	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AZF00_09910	ENOG4108W1A	pseudouridine synthase
AZF00_09930	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AZF00_09935	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AZF00_09940	ENOG4105E2Z	phosphate ABC transporter (Permease
AZF00_09945	ENOG4105C8U	phosphate abc transporter
AZF00_09955	ENOG4105BZU	Histidine kinase
AZF00_09960	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AZF00_09965	ENOG4105CIY	formyltetrahydrofolate deformylase
AZF00_09980	ENOG4105CCT	upf0313 protein
AZF00_09990	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AZF00_09995	ENOG4105WFT	During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) (By similarity)
AZF00_10000	ENOG4105FE9	pseudouridine synthase
AZF00_10005	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AZF00_10015	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AZF00_10020	ENOG4105DB7	PHP domain protein
AZF00_10030	ENOG4105K9H	YciI-like protein
AZF00_10040	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AZF00_10045	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AZF00_10055	ENOG4105CDV	Ompa motb domain protein
AZF00_10070	ENOG4105CDV	Ompa motb domain protein
AZF00_10095	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AZF00_10110	ENOG4105C8N	cysteinyl-tRNA synthetase
AZF00_10115	ENOG4105CX6	glutaminyL-tRNA synthetase
AZF00_10120	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AZF00_10125	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AZF00_10140	ENOG4105D7T	ABC transporter
AZF00_10155	ENOG4105FR9	TRNA-(Ms 2 io 6 A)-hydroxylase
AZF00_10165	ENOG4107QIJ	Aconitate hydratase 2
AZF00_10175	ENOG4108Z6B	deaminase
AZF00_10180	ENOG4105EGS	Mechanosensitive ion channel
AZF00_10195	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AZF00_10235	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AZF00_10240	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AZF00_10245	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AZF00_10250	ENOG4108IG5	Transcriptional regulator
AZF00_10260	ENOG4105D70	Integrase catalytic subunit
AZF00_10265	ENOG4105F5W	AtP-binding protein
AZF00_10270	ENOG4105IJJ	transcriptional regulator, crp fnr family
AZF00_10275	ENOG4105CRK	lysyL-tRNA synthetase
AZF00_10285	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
AZF00_10290	ENOG4105D98	threonine synthase
AZF00_10295	ENOG4105D6E	homoserine dehydrogenase
AZF00_10300	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_10305	ENOG4106YT9	Enoyl-CoA hydratase
AZF00_10320	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_10325	ENOG4105DH7	May be involved in recombination (By similarity)
AZF00_10360	ENOG4108J2P	Alpha beta hydrolase fold
AZF00_10375	ENOG4105K59	histidine triad (HIT) protein
AZF00_10415	ENOG4105HDK	L-asparaginase
AZF00_10435	ENOG41082YX	Transcriptional regulator, arsr family
AZF00_10445	ENOG4105D6J	arsenicaL-resistance protein
AZF00_10450	ENOG4108YYI	Protein of unknown function (DUF2810)
AZF00_10475	ENOG4105F8C	transglutaminase domain-containing protein
AZF00_10485	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AZF00_10490	ENOG4105C28	cystathionine
AZF00_10495	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AZF00_10500	ENOG4105E96	Colicin v production protein
AZF00_10510	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AZF00_10515	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AZF00_10520	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AZF00_10525	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AZF00_10530	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AZF00_10545	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AZF00_10550	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AZF00_10555	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AZF00_10560	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AZF00_10565	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AZF00_10570	ENOG4108MP6	LysR family Transcriptional regulator
AZF00_10575	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AZF00_10600	ENOG4108UYE	Lactoylglutathione lyase
AZF00_10610	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AZF00_10615	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AZF00_10620	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AZF00_10630	ENOG4105KWW	Biogenesis protein
AZF00_10635	ENOG4107QX9	Thiol disulfide interChange protein
AZF00_10640	ENOG4105DA4	cytochrome c-type biogenesis protein
AZF00_10645	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
AZF00_10655	ENOG41060IM	Heme exporter protein
AZF00_10660	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
AZF00_10665	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
AZF00_10675	ENOG4108VYJ	response regulator receiver protein
AZF00_10680	ENOG4107R21	site-determining protein
AZF00_10690	ENOG4105DD5	Flagellar motor switch protein
AZF00_10695	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AZF00_10705	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AZF00_10715	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AZF00_10720	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AZF00_10730	ENOG4107QJZ	Glycosyl transferase, family 2
AZF00_10750	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AZF00_10760	ENOG4107WP9	Histidine kinase
AZF00_10770	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AZF00_10785	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AZF00_10795	ENOG4105CFU	surface antigen
AZF00_10805	ENOG4105CHR	reductase
AZF00_10815	ENOG4105CV6	ABC transporter, permease
AZF00_10820	ENOG4108I0Y	(ABC) transporter
AZF00_10825	ENOG4108UJV	acyl-CoA thioesterase i
AZF00_10850	ENOG4105C9Q	fumarate hydratase class II
AZF00_10855	ENOG4105C8Y	Acetylornithine aminotransferase
AZF00_10860	ENOG4105EYW	Ion transport protein
AZF00_10875	ENOG4105EB3	Histidine kinase
AZF00_10885	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AZF00_10895	ENOG4105EBR	Carboxylesterase
AZF00_10930	ENOG4105DR9	pseudouridine synthase
AZF00_10945	ENOG4105EV9	Alpha Beta Hydrolase
AZF00_10975	ENOG4105CHF	Glutathione S-transferase
AZF00_10990	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AZF00_10995	ENOG4105IFJ	Histidine kinase
AZF00_11010	ENOG4105CDV	Ompa motb domain protein
AZF00_11055	ENOG4107STQ	Multicopper oxidase
AZF00_11065	ENOG4105C72	UPF0176 protein
AZF00_11080	ENOG4105EFT	decarboxylase
AZF00_11085	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AZF00_11110	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
AZF00_11125	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AZF00_11130	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_11135	ENOG4105EQD	regulatoR
AZF00_11145	ENOG4105BZU	Histidine kinase
AZF00_11150	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AZF00_11165	ENOG4108K5H	permease YjgP YjgQ family protein
AZF00_11170	ENOG4108M8S	permease YjgP YjgQ family protein
AZF00_11175	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AZF00_11180	ENOG4105MYG	DNA polymerase iii, chi subunit
AZF00_11190	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AZF00_11195	ENOG4105VEQ	Cold shock protein
AZF00_11200	ENOG4105BZU	Histidine kinase
AZF00_11205	ENOG4105VEQ	Cold shock protein
AZF00_11215	ENOG4108ZJT	translation initiation factor, Sui1
AZF00_11220	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AZF00_11225	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AZF00_11235	ENOG4105BZU	Histidine kinase
AZF00_11245	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AZF00_11260	ENOG4105CHR	reductase
AZF00_11270	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_11300	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AZF00_11305	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_11310	ENOG4105CEY	Amp-dependent synthetase and ligase
AZF00_11330	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
AZF00_11335	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AZF00_11345	ENOG4105CDY	transcriptional regulatory protein
AZF00_11355	ENOG4105CSV	Glutaminase
AZF00_11360	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AZF00_11380	ENOG4105CCU	oxidase (Subunit III)
AZF00_11385	ENOG4105CCU	oxidase (Subunit III)
AZF00_11390	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AZF00_11395	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
AZF00_11400	ENOG4108XM1	transcriptional regulator AsnC family
AZF00_11410	ENOG4105CHR	reductase
AZF00_11425	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
AZF00_11440	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AZF00_11450	ENOG4105NPQ	Pfam:DUF403
AZF00_11465	ENOG4107QSN	dihydrolipoamide acetyltransferase
AZF00_11470	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AZF00_11475	ENOG4107QXK	peptidase
AZF00_11485	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AZF00_11490	ENOG4105ERG	peptidase m48, ste24p
AZF00_11500	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
AZF00_11505	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AZF00_11510	ENOG4107RIQ	Sulfate adenylate transferase
AZF00_11515	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
AZF00_11520	ENOG4105DUM	transcriptional regulator, lysR family
AZF00_11535	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
AZF00_11540	ENOG4105KA0	thioesterase Superfamily protein
AZF00_11545	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_11565	ENOG4108JIR	Flagellum-specific ATP synthase
AZF00_11575	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AZF00_11580	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AZF00_11585	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
AZF00_11590	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AZF00_11600	ENOG4108JUA	Transcriptional regulator
AZF00_11610	ENOG4105MQ3	flagellar protein FliS
AZF00_11615	ENOG4105DTS	flagellar hook-associated
AZF00_11620	ENOG41063QE	flagellar protein FlaG
AZF00_11630	ENOG4105D00	flagellar biosynthetic protein flhB
AZF00_11635	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AZF00_11640	ENOG4105VS8	Flagellar biosynthetic protein fliq
AZF00_11645	ENOG4105CN7	Flagellar biosynthetic protein FliP
AZF00_11650	ENOG4105K0P	flagellar biosynthesis protein
AZF00_11655	ENOG4105DD5	Flagellar motor switch protein
AZF00_11670	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
AZF00_11680	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
AZF00_11690	ENOG4107QSA	Oxaloacetate decarboxylase
AZF00_11695	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AZF00_11705	ENOG4105K8R	UPF0145 protein
AZF00_11730	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AZF00_11740	ENOG4105D3G	Pseudouridine synthase
AZF00_11755	ENOG4105E5H	Transposase
AZF00_11795	ENOG4105CTK	cobaltochelatase, cobn subunit
AZF00_11835	ENOG4108Z66	YbaK ebsC protein
AZF00_11840	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AZF00_11845	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AZF00_11850	ENOG4105DNH	Major Facilitator
AZF00_11875	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AZF00_11880	ENOG4105BZ8	glutamate synthase
AZF00_11885	ENOG4107QM5	aconitate hydratase
AZF00_11895	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AZF00_11900	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
AZF00_11905	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AZF00_11910	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AZF00_11915	ENOG4105CXN	decarboxylase
AZF00_11920	ENOG4105CDV	Ompa motb domain protein
AZF00_11950	ENOG4105D0M	Protease HtpX homolog
AZF00_11955	ENOG4107W7X	Aldolase
AZF00_11965	ENOG4105CQ7	ATP-dependent helicase
AZF00_11970	ENOG4105I08	Pseudouridine synthase
AZF00_11975	ENOG4105QNF	Outer membrane lipoprotein
AZF00_11985	ENOG4105UGU	tonB-dependent Receptor
AZF00_11995	ENOG4105C8V	SAICAR synthetase
AZF00_12000	ENOG4105Q2H	domain protein
AZF00_12005	ENOG4105GJM	(LipO)protein
AZF00_12010	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AZF00_12035	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AZF00_12040	ENOG4105ME0	Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor (By similarity)
AZF00_12050	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
AZF00_12060	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
AZF00_12070	ENOG4105CA9	Pyruvate kinase
AZF00_12080	ENOG4105H37	Glyoxalase Bleomycin resistance protein (Dioxygenase
AZF00_12095	ENOG4105CBX	hi0933 family
AZF00_12100	ENOG4105DZ0	fad dependent oxidoreductase
AZF00_12110	ENOG4105DTD	Dehydrogenase
AZF00_12120	ENOG4108IA2	Sodium pantothenate symporter
AZF00_12125	ENOG4107ZSV	Receptor
AZF00_12140	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_12145	ENOG4107QX3	carboxylase
AZF00_12155	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
AZF00_12170	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AZF00_12195	ENOG410642W	LysR family Transcriptional regulator
AZF00_12200	ENOG4105ECP	epimerase
AZF00_12220	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_12230	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_12245	ENOG4105C0A	alcohol dehydrogenase
AZF00_12255	ENOG4105C29	acyl-CoA thioesterase
AZF00_12265	ENOG4105E39	Enoyl-CoA hydratase
AZF00_12270	ENOG4108TKH	Nitroreductase
AZF00_12275	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AZF00_12280	ENOG4105E39	Enoyl-CoA hydratase
AZF00_12310	ENOG4105WD1	Membrane
AZF00_12320	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AZF00_12325	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AZF00_12330	ENOG4105N21	Membrane
AZF00_12335	ENOG4105CUT	histidyl-tRNA synthetase
AZF00_12340	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
AZF00_12355	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AZF00_12360	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AZF00_12365	ENOG4105WVQ	Fe-S assembly protein IscX
AZF00_12370	ENOG4108ZIT	Ferredoxin, 2FE-2S
AZF00_12375	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
AZF00_12380	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
AZF00_12385	ENOG4108Z4V	iron-sulfur cluster assembly
AZF00_12390	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
AZF00_12395	ENOG4105C3J	Cysteine desulfurase
AZF00_12400	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AZF00_12410	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AZF00_12415	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AZF00_12420	ENOG4105C0B	DNA polymerase III (alpha subunit)
AZF00_12425	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AZF00_12430	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AZF00_12435	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AZF00_12440	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AZF00_12460	ENOG4105DZP	Membrane-associated zinc metalloprotease
AZF00_12465	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
AZF00_12470	ENOG4105KNE	Phosphatidate cytidylyltransferase
AZF00_12475	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AZF00_12480	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AZF00_12485	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AZF00_12490	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AZF00_12495	ENOG4105CE9	30S ribosomal protein S2
AZF00_12500	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AZF00_12510	ENOG4105CHM	Aminotransferase
AZF00_12515	ENOG4105CSM	endonuclease III
AZF00_12520	ENOG4105KUZ	arsenate reductase
AZF00_12525	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AZF00_12540	ENOG41064T2	transcriptional regulator, lysR family
AZF00_12550	ENOG4105F95	Monooxygenase
AZF00_12555	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AZF00_12575	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
AZF00_12590	ENOG4107MKT	Stringent starvation protein a
AZF00_12600	ENOG41061MV	Arylsulfatase
AZF00_12615	ENOG4105CYM	Glutathione S-transferase
AZF00_12625	ENOG4105CHR	reductase
AZF00_12635	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AZF00_12655	ENOG4108Z86	Glutamine amidotransferase
AZF00_12665	ENOG4108VWS	Yaeq family
AZF00_12715	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AZF00_12735	ENOG4105C94	Transporter
AZF00_12750	ENOG4106HB6	Alpha beta hydrolase
AZF00_12765	ENOG4106A3M	Cytochrome p-450
AZF00_12775	ENOG4108ZX5	transcriptional regulator
AZF00_12785	ENOG4105C0A	alcohol dehydrogenase
AZF00_12835	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AZF00_12865	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AZF00_12880	ENOG4105NXH	GreA GreB family elongation factor
AZF00_12885	ENOG4107R37	Glutamate dehydrogenase
AZF00_12890	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AZF00_12895	ENOG4107ZSV	Receptor
AZF00_12905	ENOG4108QIU	Dehydrogenase
AZF00_12915	ENOG4107ZQV	short-chain dehydrogenase reductase
AZF00_12925	ENOG4105NXH	GreA GreB family elongation factor
AZF00_12930	ENOG4105CHR	reductase
AZF00_12935	ENOG4108IG5	Transcriptional regulator
AZF00_12940	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AZF00_12945	ENOG4105EXW	epimerase dehydratase
AZF00_12950	ENOG4107ZSV	Receptor
AZF00_12955	ENOG4105CHR	reductase
AZF00_12980	ENOG4105C7I	Dehydrogenase
AZF00_12985	ENOG4105D8X	mechanosensitive ion channel
AZF00_12990	ENOG4105F2V	VRR-NUC domain-containing protein
AZF00_12995	ENOG4105DVT	helicase
AZF00_12995	ENOG4105DVT	helicase
AZF00_13010	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
AZF00_13020	ENOG4105CA9	Pyruvate kinase
AZF00_13025	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AZF00_13030	ENOG4106KNT	transcriptional regulator
AZF00_13035	ENOG4108UHU	Aldolase
AZF00_13040	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AZF00_13045	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AZF00_13050	ENOG4105C01	Dihydroxy-acid dehydratase
AZF00_13055	ENOG4107QP8	phosphohexose isomerase
AZF00_13065	ENOG4105DEI	Mannitol dehydrogenase
AZF00_13075	ENOG4105DKT	Transcriptional regulator
AZF00_13080	ENOG4107UB3	HAD-superfamily hydrolase subfamily IA variant 3
AZF00_13095	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AZF00_13100	ENOG410846T	CoA-transferase family III
AZF00_13105	ENOG4105E39	Enoyl-CoA hydratase
AZF00_13140	ENOG4105CKK	Glycosyl transferase, family 2
AZF00_13165	ENOG4105BZU	Histidine kinase
AZF00_13170	ENOG4105BZU	Histidine kinase
AZF00_13190	ENOG4105CHR	reductase
AZF00_13235	ENOG4105PDP	Short chain dehydrogenase
AZF00_13260	ENOG4108UT2	hemolysin iii
AZF00_13280	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AZF00_13290	ENOG4105F1S	paraquat-inducible protein a
AZF00_13295	ENOG4105DY2	Paraquat-inducible protein b
AZF00_13300	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AZF00_13315	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
AZF00_13320	ENOG4105D07	Signal peptide peptidase, SppA
AZF00_13330	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AZF00_13340	ENOG4107QX9	Thiol disulfide interChange protein
AZF00_13355	ENOG4105EE5	Membrane protein terC
AZF00_13365	ENOG4105BZU	Histidine kinase
AZF00_13385	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AZF00_13390	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AZF00_13395	ENOG4105BZU	Histidine kinase
AZF00_13400	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
AZF00_13425	ENOG4108RJ9	Glycosyl transferase, family 2
AZF00_13445	ENOG4108SHN	Glycosyl transferase, family 2
AZF00_13460	ENOG4105BZU	Histidine kinase
AZF00_13465	ENOG4105BZU	Histidine kinase
AZF00_13580	ENOG4105MP9	class II Aldolase
AZF00_13595	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AZF00_13615	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AZF00_13630	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AZF00_13655	ENOG4105G6Z	alkaline phosphatase
AZF00_13665	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AZF00_13670	ENOG4105DJV	ribulose-phosphate 3-epimerase
AZF00_13675	ENOG4108S0S	Nucleotidyl transferase
AZF00_13680	ENOG4105EHM	Aminoglycoside phosphotransferase
AZF00_13685	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
AZF00_13690	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AZF00_13695	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AZF00_13700	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AZF00_13705	ENOG4105NWN	ApaG protein
AZF00_13710	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AZF00_13715	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AZF00_13730	ENOG4105EUJ	GTP cyclohydrolase i
AZF00_13735	ENOG4107ZVW	dihydroneopterin aldolase
AZF00_13740	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AZF00_13745	ENOG4105VCC	30S ribosomal protein S21
AZF00_13755	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AZF00_13760	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AZF00_13770	ENOG4105BZU	Histidine kinase
AZF00_13775	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AZF00_13780	ENOG4105F8J	Adenylate Guanylate cyclase
AZF00_13790	ENOG4105CSH	Transporter
AZF00_13795	ENOG4105E2S	oxidase) subunit II
AZF00_13800	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AZF00_13805	ENOG4105CCU	oxidase (Subunit III)
AZF00_13810	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
AZF00_13815	ENOG4108R6F	Surfeit locus 1 family protein
AZF00_13820	ENOG4105TX3	Histidine kinase
AZF00_13825	ENOG4108UYB	regulatoR
AZF00_13875	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
AZF00_13880	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
AZF00_13885	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AZF00_13890	ENOG4105EMY	transcriptional regulator
AZF00_13895	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AZF00_13930	ENOG4107Z7P	Ferredoxin
AZF00_13935	ENOG4107ZSV	Receptor
AZF00_13945	ENOG4105C0A	alcohol dehydrogenase
AZF00_13955	ENOG4108UQN	AraC family transcriptional regulator
AZF00_13975	ENOG4107QN1	sodium solute
AZF00_13995	ENOG4105BZU	Histidine kinase
AZF00_14000	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
AZF00_14020	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
AZF00_14055	ENOG4105CHU	acetyl-coa acetyltransferase
AZF00_14060	ENOG4105C1G	acyl-Coa dehydrogenase
AZF00_14065	ENOG4108ZX5	transcriptional regulator
AZF00_14100	ENOG4108ZP8	Acetolactate synthase small subunit
AZF00_14105	ENOG4105C7K	acetolactate synthase
AZF00_14135	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AZF00_14140	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AZF00_14145	ENOG4105C34	Pseudouridine synthase
AZF00_14150	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AZF00_14155	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
AZF00_14160	ENOG4105C4K	Nad synthetase
AZF00_14165	ENOG4107TUY	Histidine kinase
AZF00_14170	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AZF00_14230	ENOG4106855	Competence protein
AZF00_14240	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
AZF00_14245	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AZF00_14250	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AZF00_14255	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AZF00_14260	ENOG4105DTN	riboflavin biosynthesis protein ribF
AZF00_14265	ENOG4105CJR	Integral membrane protein (MviN
AZF00_14270	ENOG41087AY	ADP-Ribose pyrophosphatase
AZF00_14275	ENOG4105CXT	aspartate transcarbamylase
AZF00_14280	ENOG4105BZ1	(ABC) transporter
AZF00_14285	ENOG41082IR	Excinuclease ABC C subunit domain protein
AZF00_14290	ENOG4105CJB	Exodeoxyribonuclease I
AZF00_14320	ENOG4105DSB	aldose 1-epimerase
AZF00_14335	ENOG4108UW5	maltose o-acetyltransferase
AZF00_14340	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AZF00_14345	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AZF00_14355	ENOG4105HDD	phospholipase
AZF00_14360	ENOG4108V9Q	carbonic anhydrase
AZF00_14370	ENOG4105EYM	Major Facilitator superfamily
AZF00_14375	ENOG4108VPT	UPF0234 protein
AZF00_14380	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AZF00_14385	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AZF00_14390	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AZF00_14400	ENOG4105EHG	Permease protein
AZF00_14405	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AZF00_14410	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
AZF00_14415	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AZF00_14435	ENOG4105CVJ	phosphoglycerate mutase
AZF00_14445	ENOG4108YZT	Adenosylcobinamide kinase
AZF00_14450	ENOG4108WBT	adenosyltransferase
AZF00_14455	ENOG4105DKQ	ROK family
AZF00_14460	ENOG4106A72	regulatory protein AmpE
AZF00_14465	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AZF00_14475	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AZF00_14490	ENOG4107QHF	type ii secretion system protein e
AZF00_14500	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
AZF00_14505	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AZF00_14510	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
AZF00_14515	ENOG4105M6F	mutator MutT protein
AZF00_14520	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AZF00_14525	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AZF00_14530	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AZF00_14535	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AZF00_14540	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AZF00_14545	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AZF00_14550	ENOG4105CPF	Cell wall formation (By similarity)
AZF00_14555	ENOG4105DFU	Cell wall formation (By similarity)
AZF00_14560	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AZF00_14565	ENOG4105CNI	cell division protein FtsW
AZF00_14570	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AZF00_14575	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AZF00_14580	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AZF00_14585	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AZF00_14590	ENOG4105CJN	penicillin-binding protein
AZF00_14595	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
AZF00_14600	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AZF00_14605	ENOG4108V6E	Cell division protein mraZ
AZF00_14615	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AZF00_14620	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
AZF00_14625	ENOG41082RQ	UPF0102 protein
AZF00_14630	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AZF00_14635	ENOG4105W4M	Transport-associated protein
AZF00_14640	ENOG4105KB2	stringent starvation protein b
AZF00_14645	ENOG4107MKT	Stringent starvation protein a
AZF00_14650	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AZF00_14655	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AZF00_14660	ENOG4108UJD	30S ribosomal protein S9
AZF00_14665	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AZF00_14670	ENOG4105D6Z	AFG1 family ATPase
AZF00_14680	ENOG4107QNR	UPF0135 protein
AZF00_14685	ENOG4105C0H	protease
AZF00_14690	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AZF00_14695	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AZF00_14700	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AZF00_14705	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AZF00_14720	ENOG4105C2X	Arabinose 5-phosphate isomerase
AZF00_14725	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AZF00_14740	ENOG4108IUZ	ABC transporter
AZF00_14745	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AZF00_14750	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AZF00_14755	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
AZF00_14760	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
AZF00_14765	ENOG41080Z8	PHOSPHOCARRIER protein
AZF00_14770	ENOG4105CJW	magnesium transporter
AZF00_14775	ENOG4105N42	UPF0307 protein
AZF00_14785	ENOG4105QD6	exported protein
AZF00_14790	ENOG4105C03	ribonuclease
AZF00_14795	ENOG4108Z03	MAF-like protein
AZF00_14800	ENOG4105VQ7	Rod shape-determining protein MreD
AZF00_14805	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AZF00_14810	ENOG4105DFF	Rod shape-determining protein mreb
AZF00_14815	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AZF00_14820	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AZF00_14825	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AZF00_14835	ENOG4108DG9	Smr protein MutS2
AZF00_14865	ENOG4105D06	uba thif-type nad fad binding protein
AZF00_14870	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AZF00_14875	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AZF00_14880	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AZF00_14885	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
AZF00_14895	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AZF00_14905	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AZF00_14910	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AZF00_14915	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AZF00_14920	ENOG4105C3G	gtp-binding protein
AZF00_14940	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AZF00_14945	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AZF00_14955	ENOG4105XT2	Transcriptional regulator
AZF00_14965	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AZF00_14970	ENOG4105C9A	Phoh family
AZF00_14975	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AZF00_14980	ENOG4108JU5	Magnesium and cobalt efflux protein
AZF00_14990	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AZF00_14995	ENOG4105C8T	Leucyl-tRNA synthetase
AZF00_15000	ENOG4108U2H	Rare lipoprotein B
AZF00_15015	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AZF00_15020	ENOG4108Z43	UPF0250 protein
AZF00_15025	ENOG4105DZ1	carboxypeptidase
AZF00_15030	ENOG4105K6T	rare lipoprotein A
AZF00_15035	ENOG4105CVE	Lytic murein transglycosylase
AZF00_15040	ENOG4105CNI	cell division protein FtsW
AZF00_15045	ENOG4105CJN	penicillin-binding protein
AZF00_15050	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AZF00_15060	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AZF00_15065	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AZF00_15080	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
AZF00_15085	ENOG4105DFU	Cell wall formation (By similarity)
AZF00_15140	ENOG4107R3J	Transporter
AZF00_15145	ENOG4107QZF	nitrite reductase NADPH large subunit
AZF00_15150	ENOG4105WZK	nitrite reductase NADPH small subunit
AZF00_15155	ENOG4105F0N	pyrophosphate phospho-hydrolase
AZF00_15165	ENOG4105D7W	serine acetyltransferase
AZF00_15175	ENOG4105D78	K07001 NTE family protein
AZF00_15185	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AZF00_15200	ENOG4105I08	Pseudouridine synthase
AZF00_15215	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AZF00_15220	ENOG4105C1J	atp-dependent rna helicase
AZF00_15225	ENOG4108TEB	UPF0114 protein
AZF00_15235	ENOG4108Z6Z	Transcriptional regulator
AZF00_15245	ENOG4105C1J	atp-dependent rna helicase
AZF00_15250	ENOG4105VEQ	Cold shock protein
AZF00_15255	ENOG4105CHM	Aminotransferase
AZF00_15265	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
AZF00_15275	ENOG4105TMB	Formate nitrite transporter
AZF00_15285	ENOG4107Z3H	Transcriptional regulator, TetR family
AZF00_15295	ENOG4105CR8	Transcriptional regulator
AZF00_15325	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
AZF00_15330	ENOG4107T9Q	phosphonate abc transporter
AZF00_15335	ENOG4105D5T	phosphonate abc transporter
AZF00_15345	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
AZF00_15360	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AZF00_15370	ENOG4105BZU	Histidine kinase
AZF00_15380	ENOG4105TX3	Histidine kinase
AZF00_15385	ENOG4108UYB	regulatoR
AZF00_15395	ENOG4105CDH	Citrulline--aspartate ligase
AZF00_15400	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AZF00_15405	ENOG4105F38	ABC transporter, permease
AZF00_15410	ENOG4105D38	putrescine abc transporter
AZF00_15420	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
AZF00_15425	ENOG4105EKE	dihydroorotase
AZF00_15430	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AZF00_15435	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AZF00_15440	ENOG4105D3R	alkyl hydroperoxide reductase
AZF00_15450	ENOG4108UQY	Iron-storage protein
AZF00_15470	ENOG41079HR	Phosphate-Selective Porin O and P
AZF00_15475	ENOG4105M2J	Glutaredoxin
AZF00_15485	ENOG4105D05	Receptor
AZF00_15495	ENOG4105C8Y	Acetylornithine aminotransferase
AZF00_15505	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AZF00_15510	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AZF00_15515	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AZF00_15545	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AZF00_15565	ENOG4107RGH	Aldehyde dehydrogenase
AZF00_15575	ENOG4105C09	Bile acid
AZF00_15585	ENOG4107RNH	Outer membrane receptor FepA
AZF00_15630	ENOG4108RAV	Conserved protein
AZF00_15635	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AZF00_15640	ENOG4105G2Y	Transcriptional regulator
AZF00_15645	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AZF00_15665	ENOG4105KPV	Transcriptional regulator
AZF00_15680	ENOG4106032	Glutathionylspermidine synthase
AZF00_15685	ENOG4105CYM	Glutathione S-transferase
AZF00_15695	ENOG4108IPJ	Membrane
AZF00_15770	ENOG4106VK6	Flagellar motor protein
AZF00_15775	ENOG4105E14	MotA TolQ exbB proton channel
AZF00_15810	ENOG4105CHR	reductase
AZF00_15825	ENOG4105CC0	LysR family Transcriptional regulator
AZF00_15845	ENOG4107RN6	Monooxygenase
AZF00_15860	ENOG4107ZSV	Receptor
AZF00_15880	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AZF00_15890	ENOG4105DR5	peptidase
AZF00_15895	ENOG4105DGU	Histone deacetylase
AZF00_15925	ENOG4108JJ7	ABC transporter
AZF00_15940	ENOG4105DHI	Methyltransferase
AZF00_15950	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AZF00_15980	ENOG4105DFI	Membrane
AZF00_16005	ENOG4105BZU	Histidine kinase
AZF00_16045	ENOG4105BZU	Histidine kinase
AZF00_16050	ENOG4105BZU	Histidine kinase
AZF00_16055	ENOG4108ZXC	Two component transcriptional regulator, luxr family
AZF00_16060	ENOG4105DR9	pseudouridine synthase
AZF00_16065	ENOG4105DVT	helicase
AZF00_16080	ENOG4105BZU	Histidine kinase
AZF00_16095	ENOG4105CA0	peroxidase
AZF00_16105	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AZF00_16155	ENOG4105CAU	Arsenical resistance protein, ArsH
AZF00_16165	ENOG4105CEY	Amp-dependent synthetase and ligase
AZF00_16215	ENOG4105DMF	Dehydrogenase
AZF00_16220	ENOG4107E2E	PKHD-type hydroxylase
AZF00_16225	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AZF00_16230	ENOG4107QMS	site-determining protein
AZF00_16235	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AZF00_16250	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AZF00_16255	ENOG4108UPT	UPF0178 protein
AZF00_16260	ENOG4105BZU	Histidine kinase
AZF00_16280	ENOG4105CPC	Aldo Keto reductase
AZF00_16295	ENOG4105Q26	Siderophore-interacting protein
AZF00_16315	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AZF00_16320	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AZF00_16330	ENOG4105CIS	alcohol dehydrogenase
AZF00_16335	ENOG4105EJC	lysr family transcriptional regulator
AZF00_16355	ENOG4105D6N	CoA-transferase, subunit a
AZF00_16360	ENOG4107QNJ	CoA-transferase subunit B
AZF00_16370	ENOG4107RKG	DJ-1/PfpI family
AZF00_16385	ENOG4105EV8	ectoine hydroxylase
AZF00_16390	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AZF00_16405	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AZF00_16410	ENOG4105M08	Membrane
AZF00_16415	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AZF00_16425	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
AZF00_16430	ENOG4105CAK	Cell division ATP-binding protein ftsE
AZF00_16440	ENOG4106H78	methyltransferase
AZF00_16460	ENOG4108IJF	Heavy metal efflux pump, CzcA
AZF00_16465	ENOG4108IG5	Transcriptional regulator
AZF00_16510	ENOG4109015	Biopolymer transport protein exbD tolR
AZF00_16535	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AZF00_16540	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AZF00_16545	ENOG4105HF0	Membrane
AZF00_16555	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
AZF00_16570	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AZF00_16575	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
AZF00_16580	ENOG4107QKW	extracellular solute-binding protein family 1
AZF00_16585	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AZF00_16590	ENOG4105D0A	hydroxylase
AZF00_16595	ENOG4107RAQ	aminopeptidase
AZF00_16600	ENOG4105E07	UPF0149 protein
AZF00_16610	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
AZF00_16625	ENOG4105C7B	Threonine dehydratase
AZF00_16630	ENOG4105E66	phosphoriboisomerase A
AZF00_16635	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
AZF00_16640	ENOG4105CQB	FAD linked oxidase domain protein
AZF00_16645	ENOG4108JQ1	Dehydrogenase
AZF00_16660	ENOG4105EMU	Dehydrogenase
AZF00_16675	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AZF00_16695	ENOG4105CTB	Polyprenyl synthetase
AZF00_16700	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
AZF00_16725	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
AZF00_16735	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AZF00_16740	ENOG4105I93	response regulator
AZF00_16760	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AZF00_16765	ENOG4105EUB	pirin domain protein
AZF00_16795	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AZF00_16810	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AZF00_16835	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AZF00_16840	ENOG4108ZAI	phosphatidylglycerophosphatase a
AZF00_16845	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AZF00_16850	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AZF00_16855	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AZF00_16860	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AZF00_16870	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AZF00_16875	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AZF00_16880	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AZF00_16890	ENOG4105C5H	ABC transporter
AZF00_16910	ENOG4105CHR	reductase
AZF00_16925	ENOG4105C6K	Malic enzyme
AZF00_16930	ENOG4105VFB	Binds the 23S rRNA (By similarity)
AZF00_16940	ENOG4105C25	Primosomal protein n'
AZF00_16955	ENOG4105C75	arginyL-tRNA synthetase
AZF00_16965	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AZF00_16970	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AZF00_16985	ENOG4108IAB	Phoh family
AZF00_16990	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AZF00_17010	ENOG4106371	Methyltransferase
AZF00_17025	ENOG4108R6K	riboflavin synthase, subunit alpha
AZF00_17045	ENOG4108ZG0	Ompa motb domain protein
AZF00_17065	ENOG4105DP0	ferredoxin-NADP reductase
AZF00_17070	ENOG4105DUM	transcriptional regulator, lysR family
AZF00_17075	ENOG4105C2C	drug resistance transporter, Bcr CflA
AZF00_17090	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AZF00_17110	ENOG4105MPN	Membrane
AZF00_17115	ENOG4107RGH	Aldehyde dehydrogenase
AZF00_17120	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AZF00_17125	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AZF00_17150	ENOG41060I7	thioesterase Superfamily protein
AZF00_17170	ENOG41084HI	prevent-host-death family
AZF00_17175	ENOG4105VV5	Plasmid stabilization system
AZF00_17195	ENOG4105CP2	von willebrand factor, type a
AZF00_17200	ENOG4108JU3	Alkyl hydroperoxide reductase
AZF00_17205	ENOG4105D3R	alkyl hydroperoxide reductase
AZF00_17215	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AZF00_17225	ENOG4105C5H	ABC transporter
AZF00_17230	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AZF00_17235	ENOG4105D05	Receptor
AZF00_17265	ENOG4107ZSV	Receptor
AZF00_17285	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AZF00_17300	ENOG4105C5H	ABC transporter
AZF00_17305	ENOG4105IU3	Glutathione S-transferase
AZF00_17320	ENOG4107QZM	n-acetylglutamate synthase
AZF00_17325	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AZF00_17335	ENOG4105CBS	Chea signal transduction histidine kinase
AZF00_17340	ENOG4105C8Q	Methyl-accepting chemotaxis
AZF00_17345	ENOG4108ZGA	chew protein
AZF00_17350	ENOG4105M3Z	response regulator
AZF00_17355	ENOG4108UNF	response regulator
AZF00_17360	ENOG4105D7Z	glutathione synthase
AZF00_17365	ENOG410822N	TonB family
AZF00_17370	ENOG4108UJU	UPF0301 protein
AZF00_17375	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AZF00_17380	ENOG4105CZX	twitching motility protein
AZF00_17385	ENOG4105CZX	twitching motility protein
AZF00_17390	ENOG4105DFA	alanine racemase domain protein
AZF00_17395	ENOG4105II7	pyrroline-5-carboxylate reductase
AZF00_17400	ENOG4108VIA	integral membrane protein
AZF00_17405	ENOG4105VZ9	UPF0235 protein
AZF00_17410	ENOG4105DWV	Homoserine O-trans-acetylase
AZF00_17415	ENOG4105DWV	Homoserine O-trans-acetylase
AZF00_17425	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AZF00_17455	ENOG4108IQE	Amp-dependent synthetase and ligase
AZF00_17465	ENOG4105C2C	drug resistance transporter, Bcr CflA
AZF00_17470	ENOG4105FQ6	thiopurine methyltransferase
AZF00_17485	ENOG4105WAP	TPR repeat-containing protein
AZF00_17495	ENOG4105ECF	c-methyltransferase
AZF00_17500	ENOG41076E6	Uroporphyrinogen-III Synthase
AZF00_17510	ENOG4108NEV	two component transcriptional regulator, LytTR family
AZF00_17515	ENOG4108HRK	Histidine kinase
AZF00_17525	ENOG4105CH7	arginosuccinase
AZF00_17530	ENOG4105K6T	rare lipoprotein A
AZF00_17580	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
AZF00_17600	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AZF00_17610	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AZF00_17615	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AZF00_17620	ENOG4107QHF	type ii secretion system protein e
AZF00_17625	ENOG4107IX6	phosphate transport regulator
AZF00_17630	ENOG4105CJ3	phosphate transporter
AZF00_17635	ENOG4105CWC	Acetylornithine deacetylase
AZF00_17655	ENOG4107TB6	phosphoglycerate mutase
AZF00_17675	ENOG4105VDW	Csbd family
AZF00_17685	ENOG4105W0E	50S ribosomal protein L33
AZF00_17690	ENOG4105KDC	50s ribosomal protein l28
AZF00_17695	ENOG4105W5Q	DNA repair protein (RadC
AZF00_17700	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AZF00_17705	ENOG4107QKV	phosphomannomutase
AZF00_17710	ENOG4105CAS	nag kinase
AZF00_17715	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
AZF00_17740	ENOG4105DSJ	YicC domain protein
AZF00_17765	ENOG4105GKE	subunit e
AZF00_17770	ENOG4107QIZ	NADH dehydrogenase
AZF00_17775	ENOG4108JB9	formate dehydrogenase
AZF00_17780	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AZF00_17790	ENOG4105HF0	Membrane
AZF00_17800	ENOG4105D2S	major facilitator superfamily
AZF00_17815	ENOG4105DIV	Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD( ) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds (By similarity)
AZF00_17825	ENOG4108JNI	Alpha beta hydrolase
AZF00_17845	ENOG4105VQD	rieske 2fe-2S domain-containing protein
AZF00_17850	ENOG41090TK	Short-chain dehydrogenase reductase Sdr
AZF00_17860	ENOG4105FUY	alpha subunit
AZF00_17865	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AZF00_17965	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AZF00_17970	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AZF00_17975	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AZF00_17980	ENOG4105KME	endoribonuclease L-psp
AZF00_17995	ENOG4105C5Q	Transcriptional regulator
AZF00_18000	ENOG4105CB5	ATP-dependent DNA helicase recG
AZF00_18010	ENOG4105KAF	membrAne
AZF00_18020	ENOG4105N1F	Hnh endonuclease
AZF00_18045	ENOG4105DHQ	Histidine kinase
AZF00_18050	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AZF00_18090	ENOG4106KNT	transcriptional regulator
AZF00_18100	ENOG4105C4R	Atp-dependent dna helicase
AZF00_18105	ENOG4105CH5	extracellular solute-binding protein, family 7
AZF00_18110	ENOG4105EJ2	Transcriptional regulator
AZF00_18115	ENOG410680H	amp-dependent synthetase and ligase
AZF00_18145	ENOG4105NAU	thioesterase Superfamily protein
AZF00_18150	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AZF00_18170	ENOG4105D1Q	UPF0246 protein
AZF00_18185	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
AZF00_18195	ENOG4105CFP	Peptidase U32
AZF00_18210	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AZF00_18215	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
AZF00_18220	ENOG4107QZF	nitrite reductase NADPH large subunit
AZF00_18235	ENOG4108ZF3	Phosphatase
AZF00_18245	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AZF00_18250	ENOG4105CK2	sodium dicarboxylate symporter
AZF00_18260	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AZF00_18265	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AZF00_18270	ENOG4105DXX	methyltransferase
AZF00_18290	ENOG4108JUA	Transcriptional regulator
AZF00_18295	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AZF00_18300	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AZF00_18315	ENOG4107ZSV	Receptor
AZF00_18325	ENOG4105EBR	Carboxylesterase
AZF00_18335	ENOG4105C8P	)-transporter
AZF00_18365	ENOG4105BZU	Histidine kinase
AZF00_18370	ENOG4108U5N	UPF0316 protein
AZF00_18380	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
AZF00_18405	ENOG4107RN6	Monooxygenase
AZF00_18435	ENOG4105CXG	d-lactate dehydrogenase
AZF00_18500	ENOG4107ZSV	Receptor
AZF00_18580	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AZF00_18585	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AZF00_18605	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AZF00_18610	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AZF00_18615	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AZF00_18620	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AZF00_18625	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
AZF00_18630	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AZF00_18635	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AZF00_18640	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AZF00_18645	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AZF00_18650	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AZF00_18660	ENOG4105FA0	parb-like partition protein
AZF00_18665	ENOG4107QJE	Chromosome Partitioning Protein
AZF00_18670	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AZF00_18675	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AZF00_18680	ENOG4105BZU	Histidine kinase
AZF00_18690	ENOG4107RNH	Outer membrane receptor FepA
AZF00_18695	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AZF00_18700	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AZF00_18710	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AZF00_18715	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AZF00_18720	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AZF00_18725	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AZF00_18735	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AZF00_18740	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AZF00_18745	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
AZF00_18750	ENOG4105X2V	dna damage-inducible protein
AZF00_18755	ENOG4105BZU	Histidine kinase
AZF00_18765	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AZF00_18770	ENOG4105C1A	potassium transporter peripheral membrane
AZF00_18775	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AZF00_18785	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AZF00_18795	ENOG4105C79	DNA protecting protein DprA