locus-tag	class	description
ZPR_0002	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
ZPR_0003	ENOG4105CDY	transcriptional regulatory protein
ZPR_0004	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
ZPR_0005	ENOG4105C8F	Beta-lactamase domain protein
ZPR_0008	ENOG4105C5I	Dehydrogenase
ZPR_0009	ENOG4105C5I	Dehydrogenase
ZPR_0010	ENOG41086JU	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
ZPR_0011	ENOG4105CN1	protease
ZPR_0012	ENOG4107YB6	acetyltransferase, (GNAT) family
ZPR_0013	ENOG4108YZG	isomerase
ZPR_0016	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
ZPR_0022	ENOG4107QHQ	amino acid
ZPR_0023	ENOG4105CX6	glutaminyL-tRNA synthetase
ZPR_0027	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
ZPR_0029	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
ZPR_0030	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
ZPR_0035	ENOG4107QRG	dna polymerase iii
ZPR_0036	ENOG4105BZA	Phosphoglycerate kinase
ZPR_0037	ENOG41068JE	domain protein
ZPR_0039	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ZPR_0043	ENOG4108IAJ	Nad-dependent epimerase dehydratase
ZPR_0044	ENOG4105K64	Glycosyl transferase, family 2
ZPR_0046	ENOG4107QNG	Phosphoribosylglycinamide synthetase
ZPR_0051	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
ZPR_0061	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
ZPR_0062	ENOG4105VHG	atp synthase
ZPR_0063	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
ZPR_0064	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
ZPR_0065	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
ZPR_0066	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
ZPR_0069	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
ZPR_0076	ENOG4105NAU	thioesterase Superfamily protein
ZPR_0079	ENOG4105C31	Tryptophanyl-tRNA synthetase
ZPR_0086	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
ZPR_0087	ENOG4105CFP	Peptidase U32
ZPR_0089	ENOG4105C72	UPF0176 protein
ZPR_0090	ENOG4105MA4	psp1 domain protein
ZPR_0091	ENOG410647Z	gliding motility-associated lipoprotein GldH
ZPR_0092	ENOG4108JQC	penicillin-binding protein 1A
ZPR_0093	ENOG4107QP7	CoA-transferase subunit A
ZPR_0098	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
ZPR_0101	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
ZPR_0105	ENOG4105D52	delta-aminolevulinic acid dehydratase
ZPR_0107	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
ZPR_0110	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
ZPR_0112	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
ZPR_0113	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
ZPR_0116	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
ZPR_0120	ENOG4105E39	Enoyl-CoA hydratase
ZPR_0123	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
ZPR_0127	ENOG4108Y6J	UPF0403 protein
ZPR_0128	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ZPR_0132	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
ZPR_0135	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
ZPR_0137	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
ZPR_0139	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ZPR_0140	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
ZPR_0141	ENOG4105D41	biosynthesis protein thiH
ZPR_0143	ENOG4107Y7Q	pfkb domain protein
ZPR_0144	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
ZPR_0145	ENOG4108HKT	sucrose-6-phosphate hydrolase
ZPR_0156	ENOG4105DAP	Nicotinate phosphoribosyltransferase
ZPR_0157	ENOG4108RWI	nicotinamidase
ZPR_0161	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
ZPR_0174	ENOG4105EQR	Transposase IS116 IS110 IS902
ZPR_0175	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
ZPR_0178	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ZPR_0180	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
ZPR_0182	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
ZPR_0184	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ZPR_0185	ENOG4105D78	K07001 NTE family protein
ZPR_0188	ENOG4105DEN	Luciferase family
ZPR_0189	ENOG4105F1J	Homogentisate 1,2-dioxygenase
ZPR_0190	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
ZPR_0192	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
ZPR_0194	ENOG4107QP8	phosphohexose isomerase
ZPR_0195	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ZPR_0197	ENOG4108K8S	endonuclease I
ZPR_0205	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
ZPR_0208	ENOG4105VG1	fes assembly suf system protein
ZPR_0209	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
ZPR_0217	ENOG4108Z4V	iron-sulfur cluster assembly
ZPR_0218	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
ZPR_0223	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0226	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
ZPR_0227	ENOG4107T6F	Xaa-Pro aminopeptidase
ZPR_0228	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
ZPR_0229	ENOG4105CAQ	asparagine synthetase
ZPR_0232	ENOG4105E33	succinate dehydrogenase
ZPR_0236	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
ZPR_0240	ENOG4107RPQ	ABC transporter
ZPR_0245	ENOG4105CE1	Ferrous iron transport protein b
ZPR_0248	ENOG4108KF3	Electron transport protein SCO1 SenC
ZPR_0249	ENOG4105DZP	Membrane-associated zinc metalloprotease
ZPR_0250	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
ZPR_0253	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0262	ENOG4105BZU	Histidine kinase
ZPR_0263	ENOG4107QI1	Mate efflux family protein
ZPR_0270	ENOG4105CDV	Ompa motb domain protein
ZPR_0271	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ZPR_0272	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
ZPR_0274	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
ZPR_0276	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ZPR_0277	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
ZPR_0278	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
ZPR_0279	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ZPR_0280	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
ZPR_0282	ENOG4105CA9	Pyruvate kinase
ZPR_0284	ENOG4105K4T	epimerase
ZPR_0285	ENOG41080ZE	Adenylate cyclase
ZPR_0289	ENOG4108Q35	Adenylate
ZPR_0291	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ZPR_0293	ENOG410624X	efflux transporter, rnd family, mfp subunit
ZPR_0296	ENOG4105D44	asparaginase
ZPR_0297	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
ZPR_0299	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ZPR_0302	ENOG4108NEV	two component transcriptional regulator, LytTR family
ZPR_0306	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
ZPR_0307	ENOG4105CN1	protease
ZPR_0312	ENOG4105EMU	Dehydrogenase
ZPR_0315	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ZPR_0318	ENOG4107QVM	von Willebrand factor, type A
ZPR_0323	ENOG41077A9	carbonic anhydrase
ZPR_0328	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
ZPR_0332	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
ZPR_0333	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
ZPR_0334	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
ZPR_0335	ENOG4105DSJ	YicC domain protein
ZPR_0336	ENOG4105DNZ	Alpha Beta Hydrolase
ZPR_0341	ENOG4105C28	cystathionine
ZPR_0344	ENOG4105C9B	Cysteine desulfurase
ZPR_0351	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0354	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
ZPR_0357	ENOG4105HY2	Glycosidase related protein
ZPR_0358	ENOG4105DFY	n-acylglucosamine 2-epimerase
ZPR_0359	ENOG4105EBR	Carboxylesterase
ZPR_0361	ENOG4105DYC	esterase
ZPR_0362	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
ZPR_0364	ENOG4105C8P	)-transporter
ZPR_0379	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
ZPR_0380	ENOG4105EMN	RNA polymerase sigma factor
ZPR_0384	ENOG4107ZT5	Thiol disulfide interchange protein
ZPR_0387	ENOG4107RAN	Peptidase, M16
ZPR_0390	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0392	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ZPR_0398	ENOG4106QJH	hemin transport protein
ZPR_0399	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
ZPR_0400	ENOG4105EHG	Permease protein
ZPR_0402	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ZPR_0411	ENOG4108Z6B	deaminase
ZPR_0412	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ZPR_0416	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
ZPR_0420	ENOG4105CN1	protease
ZPR_0426	ENOG4108XG2	Histidine kinase
ZPR_0427	ENOG4105WH1	Two component transcriptional regulator luxr family
ZPR_0443	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0448	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ZPR_0449	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
ZPR_0450	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
ZPR_0451	ENOG4105DTN	riboflavin biosynthesis protein ribF
ZPR_0453	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
ZPR_0457	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
ZPR_0458	ENOG4105CJW	magnesium transporter
ZPR_0459	ENOG4108JQ1	Dehydrogenase
ZPR_0462	ENOG4108UXE	Protein tyrosine phosphatase
ZPR_0465	ENOG4105CFH	Aspartokinase
ZPR_0468	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ZPR_0472	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
ZPR_0474	ENOG4107QRT	dEAD DEAH box helicase
ZPR_0476	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
ZPR_0481	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
ZPR_0482	ENOG4107YEV	ferritin
ZPR_0484	ENOG4108VVK	transcriptional Regulator, AsnC
ZPR_0486	ENOG4105M08	Membrane
ZPR_0487	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
ZPR_0490	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
ZPR_0491	ENOG4105CD3	dihydroorotase
ZPR_0494	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
ZPR_0499	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ZPR_0500	ENOG4105BZU	Histidine kinase
ZPR_0502	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
ZPR_0507	ENOG4105CAY	ferredoxin--nadp reductase
ZPR_0511	ENOG4105C1G	acyl-Coa dehydrogenase
ZPR_0512	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
ZPR_0513	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
ZPR_0514	ENOG4105CE9	30S ribosomal protein S2
ZPR_0515	ENOG4108UJD	30S ribosomal protein S9
ZPR_0516	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
ZPR_0517	ENOG4105C2M	dna polymerase I
ZPR_0521	ENOG4105K63	Thioredoxin
ZPR_0522	ENOG4108ZJ4	polysaccharide deacetylase
ZPR_0527	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0529	ENOG4105CS0	peptidase
ZPR_0538	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
ZPR_0539	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
ZPR_0540	ENOG4105C11	sulfate adenylyltransferase), subunit 2
ZPR_0542	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
ZPR_0543	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
ZPR_0544	ENOG4105C30	Nad-dependent epimerase dehydratase
ZPR_0545	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
ZPR_0551	ENOG4107XU6	Glycosyl transferase (Group 1
ZPR_0553	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
ZPR_0557	ENOG4105CPK	Glycosyl transferase (Group 1
ZPR_0561	ENOG4106WTF	Glycosyl transferase, family 2
ZPR_0562	ENOG4108IAJ	Nad-dependent epimerase dehydratase
ZPR_0565	ENOG4105D3Q	Sugar transferase
ZPR_0573	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
ZPR_0574	ENOG4105CHV	Transcription elongation factor NusA
ZPR_0575	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
ZPR_0577	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
ZPR_0578	ENOG4107SFQ	iron-sulfur binding
ZPR_0579	ENOG4105CE9	30S ribosomal protein S2
ZPR_0584	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ZPR_0585	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
ZPR_0586	ENOG41068W2	Cytochrome p-450
ZPR_0587	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
ZPR_0588	ENOG4105C6K	Malic enzyme
ZPR_0589	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
ZPR_0591	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
ZPR_0595	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
ZPR_0596	ENOG4107R3R	Cytochrome o ubiquinol oxidase subunit III
ZPR_0597	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
ZPR_0600	ENOG4108KF3	Electron transport protein SCO1 SenC
ZPR_0601	ENOG4108SJC	Membrane
ZPR_0603	ENOG4105C19	ABC transporter
ZPR_0604	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ZPR_0605	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ZPR_0606	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
ZPR_0609	ENOG41072GX	Peptidase M22 Glycoprotease
ZPR_0611	ENOG4105C7Z	Conserved Protein
ZPR_0615	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
ZPR_0618	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ZPR_0619	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
ZPR_0621	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
ZPR_0623	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
ZPR_0624	ENOG4105EV9	Alpha Beta Hydrolase
ZPR_0627	ENOG41086DT	Membrane protein of unknown function
ZPR_0628	ENOG4107V87	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
ZPR_0630	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
ZPR_0631	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
ZPR_0632	ENOG4107QSN	dihydrolipoamide acetyltransferase
ZPR_0632	ENOG4107QSN	dihydrolipoamide acetyltransferase
ZPR_0633	ENOG4107QN2	dihydrolipoyl dehydrogenase
ZPR_0634	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
ZPR_0635	ENOG4105C0B	DNA polymerase III (alpha subunit)
ZPR_0638	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
ZPR_0640	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
ZPR_0643	ENOG4105C37	(CBS) domain
ZPR_0644	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
ZPR_0647	ENOG4105C5Z	peptidase
ZPR_0648	ENOG4105DUX	Transporter
ZPR_0650	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
ZPR_0653	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ZPR_0655	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
ZPR_0656	ENOG4105CN1	protease
ZPR_0657	ENOG4105CNI	cell division protein FtsW
ZPR_0658	ENOG4105CJN	penicillin-binding protein
ZPR_0661	ENOG4105DFF	Rod shape-determining protein mreb
ZPR_0662	ENOG4105DC1	bifunctional purine biosynthesis protein purh
ZPR_0663	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ZPR_0668	ENOG4108IJF	Heavy metal efflux pump, CzcA
ZPR_0673	ENOG4105ID8	Transcriptional regulator, ARAC family
ZPR_0675	ENOG4105C59	p-type ATPase
ZPR_0676	ENOG4108M4U	conserved membrane protein
ZPR_0679	ENOG4105CRK	lysyL-tRNA synthetase
ZPR_0680	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
ZPR_0681	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0683	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ZPR_0684	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0687	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
ZPR_0688	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0690	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0701	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0713	ENOG4105CGD	Nad-dependent epimerase dehydratase
ZPR_0714	ENOG4108Z9I	-acetyltransferase
ZPR_0727	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
ZPR_0734	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
ZPR_0741	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
ZPR_0748	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0750	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0754	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
ZPR_0755	ENOG4105BZU	Histidine kinase
ZPR_0759	ENOG4105D6J	arsenicaL-resistance protein
ZPR_0764	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
ZPR_0765	ENOG4105E98	transcriptional regulator DeoR family
ZPR_0768	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
ZPR_0771	ENOG4108V06	Glutathione peroxidase
ZPR_0772	ENOG4105K56	Transcriptional regulator
ZPR_0777	ENOG4105CHH	sulfate transporter
ZPR_0778	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
ZPR_0779	ENOG4105EEQ	Na H antiporter
ZPR_0780	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
ZPR_0786	ENOG4105DR5	peptidase
ZPR_0787	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
ZPR_0791	ENOG4105MIR	Phenylalanine 4-monooxygenase
ZPR_0793	ENOG4105CGP	Urocanate hydratase
ZPR_0795	ENOG4105K6H	D-cysteine desulfhydrase
ZPR_0796	ENOG41068JE	domain protein
ZPR_0797	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
ZPR_0801	ENOG4108UW5	maltose o-acetyltransferase
ZPR_0805	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
ZPR_0806	ENOG4105KNE	Phosphatidate cytidylyltransferase
ZPR_0808	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
ZPR_0809	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
ZPR_0810	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
ZPR_0812	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
ZPR_0813	ENOG4108Z4K	mutator MutT protein
ZPR_0816	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ZPR_0818	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
ZPR_0820	ENOG4105CPF	Cell wall formation (By similarity)
ZPR_0822	ENOG4105C34	Pseudouridine synthase
ZPR_0823	ENOG4105D1Q	UPF0246 protein
ZPR_0829	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
ZPR_0830	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
ZPR_0831	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
ZPR_0832	ENOG4105DK0	Indole-3-glycerol phosphate synthase
ZPR_0833	ENOG4107RI6	Anthranilate phosphoribosyltransferase
ZPR_0834	ENOG4105DDQ	anthranilate synthase
ZPR_0835	ENOG4105CRQ	synthase (Component I)
ZPR_0836	ENOG4108YYC	ycei family
ZPR_0837	ENOG4108RCM	Nitroreductase
ZPR_0839	ENOG41085GJ	domain protein
ZPR_0840	ENOG4105C72	UPF0176 protein
ZPR_0841	ENOG4105CAK	Cell division ATP-binding protein ftsE
ZPR_0845	ENOG4105EFZ	amidohydrolase
ZPR_0846	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
ZPR_0847	ENOG4105D3R	alkyl hydroperoxide reductase
ZPR_0849	ENOG4108Z7R	Chaperone CsaA
ZPR_0850	ENOG4107ZYR	domain protein
ZPR_0854	ENOG4105BZ1	(ABC) transporter
ZPR_0855	ENOG4107RDP	Dehydrogenase
ZPR_0856	ENOG4107R6T	Involved in the transcription termination process (By similarity)
ZPR_0858	ENOG4105VIE	preprotein translocase, subunit YajC
ZPR_0860	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
ZPR_0861	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
ZPR_0862	ENOG4108NIW	Leucine export protein LeuE
ZPR_0865	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ZPR_0868	ENOG41085KW	ppic-type peptidyL-prolyl cis-trans isomerase
ZPR_0869	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ZPR_0870	ENOG4108I0Z	Aconitate hydratase
ZPR_0872	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ZPR_0876	ENOG4105EWK	phytoene
ZPR_0882	ENOG4105DZR	Type I site-specific deoxyribonuclease
ZPR_0887	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
ZPR_0888	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
ZPR_0889	ENOG4105VEJ	Heat shock protein
ZPR_0892	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
ZPR_0893	ENOG4105CV1	Transketolase (EC 2.2.1.1)
ZPR_0894	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
ZPR_0896	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
ZPR_0897	ENOG4105CDU	Replicative dna helicase
ZPR_0899	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
ZPR_0904	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0905	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0907	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_0910	ENOG4105EP8	Glycosyl Hydrolase Family 88
ZPR_0911	ENOG4105CNT	hydrolase family 2
ZPR_0918	ENOG4105DT9	hydrolase family 43
ZPR_0922	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
ZPR_0923	ENOG4105DJV	ribulose-phosphate 3-epimerase
ZPR_0924	ENOG4105DF9	Lipoate-protein, ligase
ZPR_0926	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ZPR_0928	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
ZPR_0930	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
ZPR_0931	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
ZPR_0932	ENOG4105D2N	Aldolase
ZPR_0934	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
ZPR_0936	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ZPR_0937	ENOG4105C1A	potassium transporter peripheral membrane
ZPR_0938	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
ZPR_0939	ENOG4105CHM	Aminotransferase
ZPR_0941	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
ZPR_0943	ENOG4105C26	Dehydrogenase
ZPR_0945	ENOG4105NWN	ApaG protein
ZPR_0948	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ZPR_0949	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ZPR_0950	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ZPR_0951	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ZPR_0952	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
ZPR_0955	ENOG4105CJ2	(LipO)protein
ZPR_0956	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ZPR_0960	ENOG4105K63	Thioredoxin
ZPR_0961	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
ZPR_0964	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
ZPR_0968	ENOG4105GR3	Histidine kinase
ZPR_0969	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ZPR_0970	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
ZPR_0974	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
ZPR_0975	ENOG4105BZ1	(ABC) transporter
ZPR_0978	ENOG4105C8B	TIGR00159 family
ZPR_0979	ENOG4105EEI	dihydropteroate synthase
ZPR_0982	ENOG4105CP7	Triose-phosphate isomerase
ZPR_0983	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
ZPR_0990	ENOG4108UUM	single-stranded DNA-binding protein
ZPR_0994	ENOG4105WH1	Two component transcriptional regulator luxr family
ZPR_1008	ENOG4105CNT	hydrolase family 2
ZPR_1012	ENOG4108IA2	Sodium pantothenate symporter
ZPR_1014	ENOG41073TP	transcriptional regulator
ZPR_1016	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_1020	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_1025	ENOG4105DYC	esterase
ZPR_1030	ENOG4107SYN	Glycosyl hydrolases family 43
ZPR_1031	ENOG4105CGS	Alpha-glucosidase
ZPR_1033	ENOG4105DSG	hydrolase family 43
ZPR_1035	ENOG4105BZU	Histidine kinase
ZPR_1043	ENOG4105CKW	Inner membrane protein yedI
ZPR_1045	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ZPR_1053	ENOG4108YYS	metal-dependent hydrolase (By similarity)
ZPR_1056	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
ZPR_1057	ENOG4108RR8	protoporphyrinogen oxidase
ZPR_1059	ENOG4105DEN	Luciferase family
ZPR_1060	ENOG4105BZU	Histidine kinase
ZPR_1062	ENOG41080HJ	6-phospho 3-hexuloisomerase
ZPR_1064	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
ZPR_1071	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ZPR_1073	ENOG4108IAJ	Nad-dependent epimerase dehydratase
ZPR_1074	ENOG4105DJT	lAO AO transport system ATPase
ZPR_1075	ENOG4108ZHJ	Organic hydroperoxide resistance protein
ZPR_1082	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
ZPR_1086	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ZPR_1090	ENOG4105C5H	ABC transporter
ZPR_1095	ENOG4105EY8	ABC transporter
ZPR_1100	ENOG4105K64	Glycosyl transferase, family 2
ZPR_1101	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
ZPR_1112	ENOG4105CAQ	asparagine synthetase
ZPR_1113	ENOG4105F0R	Cytidylyltransferase
ZPR_1114	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ZPR_1116	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
ZPR_1117	ENOG4105D2T	synthase
ZPR_1118	ENOG4108RJ9	Glycosyl transferase, family 2
ZPR_1120	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ZPR_1124	ENOG4107SBE	Glycosyl transferase (Group 1
ZPR_1125	ENOG4107T8Q	Glycosyl transferase (Group 1
ZPR_1128	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
ZPR_1131	ENOG4108IUZ	ABC transporter
ZPR_1133	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
ZPR_1134	ENOG4105C2X	Arabinose 5-phosphate isomerase
ZPR_1135	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ZPR_1141	ENOG4105EHZ	conserved protein UCP016719
ZPR_1142	ENOG4107R34	abc transporter permease protein
ZPR_1145	ENOG4105BZG	amino acid carrier protein
ZPR_1150	ENOG4105BZG	amino acid carrier protein
ZPR_1152	ENOG4105C1G	acyl-Coa dehydrogenase
ZPR_1153	ENOG41083X6	30S ribosomal protein S21
ZPR_1154	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ZPR_1160	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
ZPR_1163	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
ZPR_1164	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
ZPR_1165	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
ZPR_1166	ENOG4107VNI	ribosomal protein l10
ZPR_1167	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
ZPR_1168	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ZPR_1169	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ZPR_1171	ENOG4105C9X	ppx gppa phosphatase
ZPR_1172	ENOG4105BZG	amino acid carrier protein
ZPR_1173	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
ZPR_1174	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
ZPR_1178	ENOG4105DWT	malate dehydrogenase (quinone)
ZPR_1181	ENOG410667J	hydrolase
ZPR_1183	ENOG4105F6J	Alpha beta hydrolase fold
ZPR_1191	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
ZPR_1195	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ZPR_1210	ENOG4105CH2	amidohydrolase
ZPR_1214	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
ZPR_1215	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
ZPR_1219	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
ZPR_1222	ENOG4105EMN	RNA polymerase sigma factor
ZPR_1226	ENOG4105E1F	short-chain dehydrogenase reductase
ZPR_1227	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
ZPR_1229	ENOG4105C5H	ABC transporter
ZPR_1233	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
ZPR_1236	ENOG4105UMD	exodeoxyribonuclease X
ZPR_1240	ENOG4105CEV	competence damage-inducible protein
ZPR_1241	ENOG4105KDC	50s ribosomal protein l28
ZPR_1242	ENOG41083ND	50S ribosomal protein L33
ZPR_1244	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
ZPR_1245	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
ZPR_1253	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
ZPR_1261	ENOG4105C26	Dehydrogenase
ZPR_1263	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ZPR_1282	ENOG4107RAN	Peptidase, M16
ZPR_1284	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_1296	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
ZPR_1303	ENOG4105EKQ	RNA-directed DNA polymerase
ZPR_1312	ENOG4105F5W	AtP-binding protein
ZPR_1321	ENOG4105D5G	Transposase
ZPR_1346	ENOG4105ID8	Transcriptional regulator, ARAC family
ZPR_1347	ENOG4105CHR	reductase
ZPR_1352	ENOG4105D0C	transport protein
ZPR_1355	ENOG4108U51	Universal stress protein
ZPR_1356	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
ZPR_1360	ENOG4105E33	succinate dehydrogenase
ZPR_1362	ENOG4105EMU	Dehydrogenase
ZPR_1363	ENOG4105C1A	potassium transporter peripheral membrane
ZPR_1364	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
ZPR_1367	ENOG41065SU	Two-component system sensor kinase
ZPR_1369	ENOG4105FQP	Beta-lactamase
ZPR_1376	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
ZPR_1379	ENOG4105C5Z	peptidase
ZPR_1380	ENOG4105TT1	Ragb susd domain-containing protein
ZPR_1381	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_1382	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
ZPR_1383	ENOG4105CTU	Proline racemase
ZPR_1385	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ZPR_1386	ENOG4108R6W	Transcriptional regulator, ARAC family
ZPR_1388	ENOG4105CNT	hydrolase family 2
ZPR_1389	ENOG4107RAQ	aminopeptidase
ZPR_1401	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
ZPR_1402	ENOG4105BZ9	Cytochrome C oxidase, subunit I
ZPR_1403	ENOG4105CCU	oxidase (Subunit III)
ZPR_1406	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
ZPR_1407	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
ZPR_1408	ENOG4105CBC	glutamate synthase
ZPR_1428	ENOG4107QUT	magnesium and cobalt transport protein CorA
ZPR_1431	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
ZPR_1443	ENOG4107ZXU	DSBA oxidoreductase
ZPR_1454	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ZPR_1456	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
ZPR_1458	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
ZPR_1463	ENOG4105C3F	Signal peptidase i
ZPR_1464	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
ZPR_1466	ENOG4105FA0	parb-like partition protein
ZPR_1467	ENOG4107QJE	Chromosome Partitioning Protein
ZPR_1468	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
ZPR_1469	ENOG4105D5P	Methylmalonyl-coA mutase
ZPR_1470	ENOG4105CMN	Methylmalonyl-coA mutase
ZPR_1472	ENOG4105DBI	uridine monophosphokinase
ZPR_1473	ENOG4107TJ9	Cytochrome
ZPR_1474	ENOG4105D8V	Glucose sorbosone dehydrogenase
ZPR_1476	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ZPR_1479	ENOG4105GR3	Histidine kinase
ZPR_1482	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
ZPR_1496	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ZPR_1513	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ZPR_1521	ENOG4105DQ6	Transposase
ZPR_1541	ENOG4105CNT	hydrolase family 2
ZPR_1547	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_1548	ENOG4105CMD	Transcriptional regulator, GntR family
ZPR_1550	ENOG4105C9F	isomerase
ZPR_1552	ENOG4105DMF	Dehydrogenase
ZPR_1554	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_1565	ENOG4105M5P	UPF0310 protein
ZPR_1570	ENOG4105D05	Receptor
ZPR_1582	ENOG4105CA0	peroxidase
ZPR_1588	ENOG4107KET	secretion protein, HlyD family
ZPR_1589	ENOG4108IG5	Transcriptional regulator
ZPR_1590	ENOG4108V06	Glutathione peroxidase
ZPR_1604	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
ZPR_1605	ENOG4105CBG	Sulfatase
ZPR_1607	ENOG4105D05	Receptor
ZPR_1615	ENOG4105BZU	Histidine kinase
ZPR_1629	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_1637	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ZPR_1640	ENOG4107VIJ	nudix hydrolase
ZPR_1642	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
ZPR_1643	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
ZPR_1644	ENOG4105F27	Major Facilitator
ZPR_1645	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
ZPR_1647	ENOG4107T8T	UPF0173 metal-dependent hydrolase
ZPR_1651	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
ZPR_1654	ENOG4105CI2	imidazolone-5-propionate hydrolase
ZPR_1655	ENOG4105KWG	Pfam:DUF1696
ZPR_1656	ENOG4105DQ4	alcohol dehydrogenase
ZPR_1657	ENOG4105C7K	acetolactate synthase
ZPR_1658	ENOG4105C28	cystathionine
ZPR_1659	ENOG4105FJR	Lmbe family
ZPR_1663	ENOG4105DXN	mazG family
ZPR_1664	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
ZPR_1666	ENOG4105E2X	shikimate dehydrogenase
ZPR_1670	ENOG4105C8Y	Acetylornithine aminotransferase
ZPR_1674	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ZPR_1675	ENOG41090R7	Ferric uptake
ZPR_1676	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
ZPR_1678	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
ZPR_1679	ENOG4108RWN	rrna methyltransferase
ZPR_1681	ENOG4105CI2	imidazolone-5-propionate hydrolase
ZPR_1684	ENOG4105CIN	aminoacyl-histidine dipeptidase
ZPR_1686	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
ZPR_1688	ENOG4105SFS	phosphoesterase RecJ domain protein
ZPR_1690	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
ZPR_1691	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
ZPR_1692	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ZPR_1693	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ZPR_1694	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
ZPR_1697	ENOG4105BZP	glycoside hydrolase 15-related
ZPR_1698	ENOG4105BZP	glycoside hydrolase 15-related
ZPR_1701	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
ZPR_1707	ENOG4105EJQ	L-serine dehydratase
ZPR_1708	ENOG4105CFG	Acts as a chaperone (By similarity)
ZPR_1710	ENOG4105K3M	)-transporter
ZPR_1713	ENOG4105KA0	thioesterase Superfamily protein
ZPR_1714	ENOG4105E4F	Isochorismate synthase
ZPR_1715	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
ZPR_1718	ENOG4105QNR	S1 RNA binding domain protein
ZPR_1730	ENOG4105CPP	Dehydrogenase, E1 component
ZPR_1732	ENOG4108URH	decarboxylase
ZPR_1733	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ZPR_1735	ENOG4107QKV	phosphomannomutase
ZPR_1740	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ZPR_1748	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
ZPR_1749	ENOG4105KME	endoribonuclease L-psp
ZPR_1751	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_1756	ENOG4105EE1	crotonyl-CoA reductase
ZPR_1757	ENOG4105FA0	parb-like partition protein
ZPR_1759	ENOG4107XMK	single-stranded DNA-binding protein
ZPR_1768	ENOG4105CB5	ATP-dependent DNA helicase recG
ZPR_1776	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
ZPR_1784	ENOG4105JD4	ATPase yjob
ZPR_1794	ENOG4107TPS	domain protein
ZPR_1796	ENOG4105D3R	alkyl hydroperoxide reductase
ZPR_1797	ENOG4105C72	UPF0176 protein
ZPR_1798	ENOG4105C72	UPF0176 protein
ZPR_1804	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
ZPR_1810	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
ZPR_1811	ENOG4108RMU	ferritin dps family protein
ZPR_1812	ENOG4108RMU	ferritin dps family protein
ZPR_1814	ENOG4105CGH	5'-nucleotidase
ZPR_1817	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ZPR_1818	ENOG4105CGH	5'-nucleotidase
ZPR_1828	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ZPR_1829	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
ZPR_1831	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
ZPR_1836	ENOG4105C9A	Phoh family
ZPR_1837	ENOG4107QWK	SAICAR synthetase
ZPR_1838	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
ZPR_1855	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
ZPR_1856	ENOG4105C8Y	Acetylornithine aminotransferase
ZPR_1863	ENOG4105C3J	Cysteine desulfurase
ZPR_1867	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
ZPR_1869	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ZPR_1872	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
ZPR_1876	ENOG4105E0X	reductase
ZPR_1877	ENOG4105E0X	reductase
ZPR_1880	ENOG4105DEU	major facilitator superfamily
ZPR_1884	ENOG4105GFR	rna polymerase sigma factor
ZPR_1885	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
ZPR_1886	ENOG4105CAT	Cytidine monophosphate kinase
ZPR_1889	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
ZPR_1891	ENOG4107QQR	Sporulation
ZPR_1892	ENOG4105BZU	Histidine kinase
ZPR_1896	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
ZPR_1897	ENOG4107FQ9	ethanolamine ammonia-lyase
ZPR_1898	ENOG4105CPD	ethanolamine ammonia-lyase
ZPR_1899	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
ZPR_1900	ENOG4108ZHJ	Organic hydroperoxide resistance protein
ZPR_1901	ENOG4105K56	Transcriptional regulator
ZPR_1902	ENOG4107TRE	AP endonuclease, family 2
ZPR_1903	ENOG4107Y2X	deaminase
ZPR_1905	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
ZPR_1906	ENOG4105CXT	aspartate transcarbamylase
ZPR_1908	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
ZPR_1909	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
ZPR_1912	ENOG4107R33	ppx gppa phosphatase
ZPR_1914	ENOG4105C6E	dna polymerase iii
ZPR_1917	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
ZPR_1918	ENOG4105GR3	Histidine kinase
ZPR_1921	ENOG4105CJ2	(LipO)protein
ZPR_1936	ENOG4108I0Y	(ABC) transporter
ZPR_1937	ENOG4105K5X	acetyltransferase
ZPR_1938	ENOG4108UJV	acyl-CoA thioesterase i
ZPR_1944	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
ZPR_1945	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
ZPR_1947	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ZPR_1954	ENOG4105DY9	regulatoR
ZPR_1960	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
ZPR_1963	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_1965	ENOG4105G6Z	alkaline phosphatase
ZPR_1966	ENOG4105G6Z	alkaline phosphatase
ZPR_1973	ENOG4105ETU	transcriptional activator (TenA
ZPR_1975	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
ZPR_1976	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
ZPR_1979	ENOG4105KVH	Transcriptional regulator
ZPR_1980	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
ZPR_1984	ENOG4108VCT	Sulfite exporter TauE/SafE
ZPR_1987	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
ZPR_1988	ENOG4105VZ8	Transcriptional regulator
ZPR_1996	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
ZPR_1998	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ZPR_1999	ENOG4107QX3	carboxylase
ZPR_2000	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
ZPR_2001	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
ZPR_2003	ENOG4105EUB	pirin domain protein
ZPR_2005	ENOG41090U3	tautomerase
ZPR_2006	ENOG41076HS	cation diffusion facilitator family transporter
ZPR_2009	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ZPR_2010	ENOG4105D7N	magnesium and cobalt transport protein CorA
ZPR_2011	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
ZPR_2015	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
ZPR_2017	ENOG4105D64	Mechanosensitive ion channel
ZPR_2018	ENOG4105DWY	Agmatine deiminase
ZPR_2019	ENOG4105ES4	Nitrilase
ZPR_2020	ENOG4108V1T	peptidylprolyl cis-trans isomerase
ZPR_2024	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
ZPR_2028	ENOG4105EMN	RNA polymerase sigma factor
ZPR_2029	ENOG4105BZ1	(ABC) transporter
ZPR_2031	ENOG4105CKK	Glycosyl transferase, family 2
ZPR_2033	ENOG41081WG	50s ribosomal protein l31
ZPR_2038	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ZPR_2040	ENOG4105C2I	pirin domain protein
ZPR_2047	ENOG4105VG0	50S ribosomal protein l34
ZPR_2053	ENOG4105NAU	thioesterase Superfamily protein
ZPR_2056	ENOG4105CGY	Dna recombination protein
ZPR_2057	ENOG4105E0A	ABC, transporter
ZPR_2058	ENOG4108IHU	transport system permease protein
ZPR_2060	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
ZPR_2069	ENOG4105CPN	adenine deaminase
ZPR_2072	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_2073	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
ZPR_2074	ENOG4105GYP	Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline (By similarity)
ZPR_2075	ENOG4105D7W	serine acetyltransferase
ZPR_2076	ENOG4105C6T	cysteine synthase
ZPR_2080	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
ZPR_2084	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
ZPR_2086	ENOG4105CBC	glutamate synthase
ZPR_2087	ENOG41081QV	Universal stress protein
ZPR_2093	ENOG41087YS	Phage shock protein A
ZPR_2100	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
ZPR_2101	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
ZPR_2103	ENOG4105HFZ	Membrane
ZPR_2104	ENOG4107QTF	adenylosuccinate lyase
ZPR_2106	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
ZPR_2108	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
ZPR_2111	ENOG4105C1J	atp-dependent rna helicase
ZPR_2112	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
ZPR_2113	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
ZPR_2114	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
ZPR_2115	ENOG4107U9T	Pfam:Ribonuclease_BN
ZPR_2118	ENOG4105C25	Primosomal protein n'
ZPR_2119	ENOG4108NEV	two component transcriptional regulator, LytTR family
ZPR_2120	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
ZPR_2121	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
ZPR_2122	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
ZPR_2124	ENOG4107RBB	ABC transporter, permease
ZPR_2125	ENOG4105CUT	histidyl-tRNA synthetase
ZPR_2129	ENOG4107ENK	receptor
ZPR_2134	ENOG4108JQ1	Dehydrogenase
ZPR_2135	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
ZPR_2137	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
ZPR_2141	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
ZPR_2144	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
ZPR_2146	ENOG4105EF1	ribulokinase
ZPR_2147	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
ZPR_2148	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
ZPR_2149	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
ZPR_2153	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_2159	ENOG4105CWX	Alpha-1,2-mannosidase
ZPR_2194	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
ZPR_2200	ENOG4105DC8	reductase
ZPR_2203	ENOG4105KAF	membrAne
ZPR_2206	ENOG4108XG2	Histidine kinase
ZPR_2208	ENOG4105D82	Glutamate dehydrogenase
ZPR_2210	ENOG4105BZU	Histidine kinase
ZPR_2212	ENOG4105KPY	Small multidrug resistance protein
ZPR_2213	ENOG4108HRK	Histidine kinase
ZPR_2214	ENOG4105DY9	regulatoR
ZPR_2216	ENOG4105DG6	mannose-6-phosphate isomerase
ZPR_2218	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ZPR_2223	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
ZPR_2226	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
ZPR_2236	ENOG4105T16	Transcriptional regulator (AraC family)
ZPR_2240	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_2251	ENOG4105D8X	mechanosensitive ion channel
ZPR_2252	ENOG4108RMU	ferritin dps family protein
ZPR_2255	ENOG4105ETE	Transcriptional regulator (LacI family
ZPR_2256	ENOG4108IAJ	Nad-dependent epimerase dehydratase
ZPR_2257	ENOG4107QQG	Dehydrogenase
ZPR_2258	ENOG4105D3Q	Sugar transferase
ZPR_2259	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ZPR_2267	ENOG4105CFH	Aspartokinase
ZPR_2268	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
ZPR_2269	ENOG4105D98	threonine synthase
ZPR_2275	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
ZPR_2277	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
ZPR_2278	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
ZPR_2279	ENOG4105II7	pyrroline-5-carboxylate reductase
ZPR_2280	ENOG4105BZU	Histidine kinase
ZPR_2281	ENOG4105BZU	Histidine kinase
ZPR_2284	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
ZPR_2288	ENOG4105DGW	oligopeptidase A
ZPR_2291	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
ZPR_2292	ENOG4105S64	Formate nitrite transporter
ZPR_2293	ENOG4105BZU	Histidine kinase
ZPR_2297	ENOG4107QJZ	Glycosyl transferase, family 2
ZPR_2299	ENOG4105C59	p-type ATPase
ZPR_2301	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
ZPR_2303	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
ZPR_2304	ENOG4105C58	cytochrome c oxidase accessory protein ccog
ZPR_2312	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
ZPR_2313	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
ZPR_2314	ENOG4105CHR	reductase
ZPR_2321	ENOG4105D64	Mechanosensitive ion channel
ZPR_2323	ENOG4108Z03	MAF-like protein
ZPR_2327	ENOG4105CRE	cytochrome C
ZPR_2328	ENOG4105C9Q	fumarate hydratase class II
ZPR_2330	ENOG4107RNH	Outer membrane receptor FepA
ZPR_2332	ENOG4105K89	arsenate reductase
ZPR_2333	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
ZPR_2341	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
ZPR_2344	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ZPR_2351	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ZPR_2354	ENOG4105CS1	NAD(P)H quinone oxidoreductase
ZPR_2355	ENOG4105CSM	endonuclease III
ZPR_2356	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ZPR_2358	ENOG4105DCF	alanine dehydrogenase
ZPR_2361	ENOG4105K8N	protein family UPF0079, ATPase
ZPR_2362	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ZPR_2363	ENOG4105DCI	Phosphohydrolase
ZPR_2364	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ZPR_2365	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ZPR_2366	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ZPR_2367	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
ZPR_2368	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
ZPR_2378	ENOG4105CHR	reductase
ZPR_2381	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
ZPR_2387	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
ZPR_2388	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ZPR_2389	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
ZPR_2390	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
ZPR_2392	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
ZPR_2394	ENOG4105C5I	Dehydrogenase
ZPR_2397	ENOG4105EN6	Membrane
ZPR_2398	ENOG4105C3M	thioredoxin reductase
ZPR_2411	ENOG4105C5Q	Transcriptional regulator
ZPR_2414	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
ZPR_2421	ENOG4105P8F	nudix hydrolase
ZPR_2422	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
ZPR_2427	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_2429	ENOG4108HRK	Histidine kinase
ZPR_2432	ENOG4105DY9	regulatoR
ZPR_2435	ENOG4105K6V	RNA polymerase
ZPR_2440	ENOG4105EAA	nucleoside
ZPR_2449	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_2459	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
ZPR_2461	ENOG4105BZP	glycoside hydrolase 15-related
ZPR_2467	ENOG4105C1G	acyl-Coa dehydrogenase
ZPR_2468	ENOG4105CHU	acetyl-coa acetyltransferase
ZPR_2470	ENOG4105FS7	Transcriptional regulator
ZPR_2471	ENOG4108IQE	Amp-dependent synthetase and ligase
ZPR_2473	ENOG4108ETH	Formylglycinamide ribotide synthetase
ZPR_2474	ENOG4108K8S	endonuclease I
ZPR_2475	ENOG4105E1F	short-chain dehydrogenase reductase
ZPR_2487	ENOG4105BZU	Histidine kinase
ZPR_2488	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_2491	ENOG4105CNT	hydrolase family 2
ZPR_2492	ENOG4105CJQ	hydrolase, family 31
ZPR_2494	ENOG4105DKQ	ROK family
ZPR_2507	ENOG4105FTV	AraC Family Transcriptional Regulator
ZPR_2511	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
ZPR_2515	ENOG4108Q35	Adenylate
ZPR_2522	ENOG4105F0I	Aminotransferase
ZPR_2525	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
ZPR_2526	ENOG4105C9U	ATP-dependent DNA helicase RecQ
ZPR_2528	ENOG4108D64	Protein of unknown function (DUF493)
ZPR_2530	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
ZPR_2532	ENOG4105E0K	tonB-dependent siderophore receptor
ZPR_2534	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
ZPR_2537	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
ZPR_2538	ENOG4105C6K	Malic enzyme
ZPR_2541	ENOG4105CD3	dihydroorotase
ZPR_2543	ENOG4105C08	Histidine kinase
ZPR_2546	ENOG4107V8H	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ZPR_2547	ENOG4105EUJ	GTP cyclohydrolase i
ZPR_2549	ENOG4105QIV	RNA polymerase
ZPR_2551	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
ZPR_2553	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
ZPR_2555	ENOG4107ZT5	Thiol disulfide interchange protein
ZPR_2556	ENOG4108JQC	penicillin-binding protein 1A
ZPR_2557	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
ZPR_2558	ENOG4105GR3	Histidine kinase
ZPR_2567	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
ZPR_2569	ENOG4108Z9K	Osmotically inducible protein
ZPR_2571	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
ZPR_2572	ENOG4105D9R	oxidoreductase
ZPR_2577	ENOG4105CFH	Aspartokinase
ZPR_2581	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ZPR_2582	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
ZPR_2583	ENOG4105C6Z	Gluconate
ZPR_2585	ENOG4105CDY	transcriptional regulatory protein
ZPR_2586	ENOG4105KZX	Pterin carbinolamine dehydratase
ZPR_2588	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
ZPR_2589	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
ZPR_2590	ENOG4105C84	Histidine ammonia-lyase
ZPR_2593	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ZPR_2596	ENOG4105CHU	acetyl-coa acetyltransferase
ZPR_2605	ENOG4108S4H	thioesterase Superfamily protein
ZPR_2606	ENOG4105D64	Mechanosensitive ion channel
ZPR_2608	ENOG4105CUY	Mechanosensitive ion channel
ZPR_2609	ENOG4105VCH	membrane
ZPR_2610	ENOG4105CMR	udp-glucose 4-epimerase
ZPR_2616	ENOG4105CHR	reductase
ZPR_2618	ENOG4105H3G	oxidoreductase
ZPR_2619	ENOG4105EMU	Dehydrogenase
ZPR_2620	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
ZPR_2622	ENOG4105EM2	membrane
ZPR_2626	ENOG4105CIH	Imidazole acetol-phosphate transaminase
ZPR_2629	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
ZPR_2631	ENOG4105CIS	alcohol dehydrogenase
ZPR_2634	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
ZPR_2638	ENOG4105DUM	transcriptional regulator, lysR family
ZPR_2639	ENOG4105HMI	Membrane
ZPR_2640	ENOG4108YZG	isomerase
ZPR_2641	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
ZPR_2642	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
ZPR_2647	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
ZPR_2648	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
ZPR_2654	ENOG4105VEQ	Cold shock protein
ZPR_2691	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
ZPR_2693	ENOG4105UYK	outer membrane protein a
ZPR_2700	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
ZPR_2701	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
ZPR_2704	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
ZPR_2705	ENOG4105C98	muts2 protein
ZPR_2706	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
ZPR_2710	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
ZPR_2713	ENOG4105D49	3-dehydroquinate synthase
ZPR_2715	ENOG4108Z0Z	intracellular protease Pfpi family
ZPR_2718	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
ZPR_2719	ENOG4108VVK	transcriptional Regulator, AsnC
ZPR_2723	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
ZPR_2724	ENOG4105DF5	DNA topoisomerase IV, subunit A
ZPR_2726	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
ZPR_2727	ENOG4105C3G	gtp-binding protein
ZPR_2729	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ZPR_2730	ENOG4106Z5D	Glycoside Hydrolase Family 43
ZPR_2731	ENOG4105CWX	Alpha-1,2-mannosidase
ZPR_2732	ENOG4105CWX	Alpha-1,2-mannosidase
ZPR_2734	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
ZPR_2736	ENOG4105CPK	Glycosyl transferase (Group 1
ZPR_2737	ENOG4105D17	glycoside hydrolase, family 3 domain protein
ZPR_2739	ENOG4105DF6	Fe-S oxidoreductase
ZPR_2740	ENOG4105DF6	Fe-S oxidoreductase
ZPR_2742	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
ZPR_2746	ENOG4105CPC	Aldo Keto reductase
ZPR_2748	ENOG4108ZIE	5 nucleotidase deoxy cytosolic type C
ZPR_2750	ENOG4108Z5K	methylglyoxal synthase
ZPR_2751	ENOG4105CTQ	phosphohexokinase
ZPR_2753	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ZPR_2763	ENOG4107QJZ	Glycosyl transferase, family 2
ZPR_2764	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ZPR_2766	ENOG4108ZJ4	polysaccharide deacetylase
ZPR_2768	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ZPR_2773	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
ZPR_2775	ENOG4105CHR	reductase
ZPR_2776	ENOG4105C84	Histidine ammonia-lyase
ZPR_2780	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ZPR_2793	ENOG4107REN	Carbamoyltransferase
ZPR_2794	ENOG4105C8Y	Acetylornithine aminotransferase
ZPR_2796	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
ZPR_2797	ENOG4105CDH	Citrulline--aspartate ligase
ZPR_2799	ENOG4105C7B	Threonine dehydratase
ZPR_2800	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
ZPR_2802	ENOG4105C7K	acetolactate synthase
ZPR_2804	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
ZPR_2807	ENOG4105P4J	Allophanate hydrolase, subunit 1
ZPR_2809	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
ZPR_2811	ENOG4105C0P	Mg chelatase subunit ChlI
ZPR_2813	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
ZPR_2814	ENOG4105CTQ	phosphohexokinase
ZPR_2815	ENOG4105CG3	alpha amylase, catalytic region
ZPR_2816	ENOG4108IUK	alpha amylase, catalytic
ZPR_2819	ENOG4107URF	beta-phospho-glucomutase
ZPR_2822	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_2825	ENOG4105E5K	Alpha-amylase
ZPR_2833	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
ZPR_2834	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
ZPR_2836	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
ZPR_2839	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
ZPR_2840	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
ZPR_2841	ENOG4105CRQ	synthase (Component I)
ZPR_2844	ENOG4105C1J	atp-dependent rna helicase
ZPR_2846	ENOG4108HRK	Histidine kinase
ZPR_2848	ENOG4108NEV	two component transcriptional regulator, LytTR family
ZPR_2851	ENOG4107QN2	dihydrolipoyl dehydrogenase
ZPR_2853	ENOG4105DFD	Na H antiporter
ZPR_2854	ENOG4105D3R	alkyl hydroperoxide reductase
ZPR_2857	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
ZPR_2860	ENOG4105CNU	cell division protein FtsK
ZPR_2864	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
ZPR_2871	ENOG4108HCJ	Hydrolase
ZPR_2876	ENOG4108JQ1	Dehydrogenase
ZPR_2877	ENOG4107RH8	nuclease SbcCD subunit D
ZPR_2878	ENOG4105EYH	Exonuclease
ZPR_2880	ENOG4108UT2	hemolysin iii
ZPR_2895	ENOG4105EPC	oxidoreductase
ZPR_2898	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_2902	ENOG4105ETE	Transcriptional regulator (LacI family
ZPR_2906	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
ZPR_2907	ENOG4105VRT	cytoplasmic protein
ZPR_2908	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
ZPR_2909	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
ZPR_2913	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ZPR_2914	ENOG41068JE	domain protein
ZPR_2917	ENOG4108W2Y	isochorismatase
ZPR_2920	ENOG4105EA8	2-Nitropropane dioxygenase
ZPR_2921	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
ZPR_2926	ENOG4105DUM	transcriptional regulator, lysR family
ZPR_2927	ENOG4105EVH	UPF0753 protein
ZPR_2928	ENOG4108TWJ	NADH dehydrogenase subunit 5
ZPR_2929	ENOG4105DY8	decarboxylase
ZPR_2930	ENOG41074B2	UPF0747 protein
ZPR_2936	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_2938	ENOG4105CNT	hydrolase family 2
ZPR_2943	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
ZPR_2951	ENOG4105ETE	Transcriptional regulator (LacI family
ZPR_2952	ENOG4105CTX	dehydratase
ZPR_2953	ENOG4107QZW	Altronate oxidoreductase
ZPR_2954	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ZPR_2955	ENOG41069H7	transport system small permease component
ZPR_2956	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ZPR_2958	ENOG4105DMF	Dehydrogenase
ZPR_2960	ENOG4105D2H	Uronic isomerase
ZPR_2961	ENOG4105CHR	reductase
ZPR_2962	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
ZPR_2968	ENOG4105DMW	Dehydrogenase reductase
ZPR_2970	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
ZPR_2971	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
ZPR_2973	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
ZPR_2974	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
ZPR_2975	ENOG4108XHQ	(2Fe-2S)-binding domain protein
ZPR_2977	ENOG4108ZAF	Molybdopterin
ZPR_2978	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ZPR_2979	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
ZPR_2981	ENOG4105D06	uba thif-type nad fad binding protein
ZPR_2982	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
ZPR_2984	ENOG4105E0C	molybdate abc transporter
ZPR_2985	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
ZPR_2987	ENOG4105C7W	Xanthine dehydrogenase
ZPR_2988	ENOG4105DIP	Molybdopterin dehydrogenase FAD-binding
ZPR_2989	ENOG4107XKX	isoquinoline 1-oxidoreductase, alpha subunit
ZPR_2991	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ZPR_2995	ENOG4105C93	Xylose Isomerase
ZPR_2996	ENOG4105CMG	Carbohydrate kinase
ZPR_2997	ENOG4105E6M	Sulphatase-modifying factor protein
ZPR_3019	ENOG4107TPS	domain protein
ZPR_3024	ENOG4107QNK	)-transporter
ZPR_3027	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
ZPR_3030	ENOG4105DT9	hydrolase family 43
ZPR_3031	ENOG4105ETE	Transcriptional regulator (LacI family
ZPR_3032	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
ZPR_3033	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
ZPR_3034	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
ZPR_3035	ENOG4105D2H	Uronic isomerase
ZPR_3037	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
ZPR_3038	ENOG4105CHR	reductase
ZPR_3039	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
ZPR_3042	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3045	ENOG4107QI1	Mate efflux family protein
ZPR_3049	ENOG4105VN1	Heat shock protein
ZPR_3051	ENOG4105ENE	Histidine kinase
ZPR_3052	ENOG4105WH1	Two component transcriptional regulator luxr family
ZPR_3053	ENOG4105C5H	ABC transporter
ZPR_3056	ENOG4107QX3	carboxylase
ZPR_3062	ENOG4107FCW	Abortive infection protein
ZPR_3063	ENOG4105DTQ	mandelate racemase muconate lactonizing
ZPR_3064	ENOG4107W2A	UPF0173 metal-dependent hydrolase
ZPR_3065	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
ZPR_3069	ENOG4105ER2	Ompa motb domain protein
ZPR_3073	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3075	ENOG4105KCK	Peptidoglycan-associated lipoprotein
ZPR_3081	ENOG4105D8X	mechanosensitive ion channel
ZPR_3084	ENOG4108UY2	Chloramphenicol acetyltransferase
ZPR_3085	ENOG4105VDW	Csbd family
ZPR_3088	ENOG4105C26	Dehydrogenase
ZPR_3090	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
ZPR_3093	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
ZPR_3096	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
ZPR_3097	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
ZPR_3098	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
ZPR_3103	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
ZPR_3104	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
ZPR_3113	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
ZPR_3115	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ZPR_3117	ENOG4105EGS	Mechanosensitive ion channel
ZPR_3118	ENOG4105RHA	ABC transporter, permease
ZPR_3119	ENOG4108IUX	(ABC) transporter
ZPR_3121	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
ZPR_3122	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ZPR_3125	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
ZPR_3127	ENOG4105CM2	brancheD-chain amino acid aminotransferase
ZPR_3132	ENOG41083GQ	Protein CrcB homolog
ZPR_3133	ENOG4108YZA	Nitrogen regulatory protein pii
ZPR_3142	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
ZPR_3143	ENOG4105D5P	Methylmalonyl-coA mutase
ZPR_3145	ENOG4105CH6	catalase
ZPR_3148	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
ZPR_3149	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
ZPR_3150	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
ZPR_3151	ENOG4105CZV	ABC transporter
ZPR_3153	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
ZPR_3155	ENOG4107R5B	glutamine synthetase
ZPR_3162	ENOG4105WH1	Two component transcriptional regulator luxr family
ZPR_3169	ENOG4105TT1	Ragb susd domain-containing protein
ZPR_3170	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3171	ENOG4105C2C	drug resistance transporter, Bcr CflA
ZPR_3176	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3183	ENOG4105CKI	cobalamin synthesis protein
ZPR_3185	ENOG4105G6Z	alkaline phosphatase
ZPR_3188	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3194	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3196	ENOG4108HKT	sucrose-6-phosphate hydrolase
ZPR_3197	ENOG4105C54	Major Facilitator superfamily
ZPR_3217	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ZPR_3218	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
ZPR_3224	ENOG4107VAM	peptidase, m28
ZPR_3227	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
ZPR_3230	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
ZPR_3232	ENOG4105DFA	alanine racemase domain protein
ZPR_3233	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
ZPR_3235	ENOG4105EYW	Ion transport protein
ZPR_3236	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
ZPR_3241	ENOG4107QJZ	Glycosyl transferase, family 2
ZPR_3242	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
ZPR_3243	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
ZPR_3248	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
ZPR_3252	ENOG4105CGH	5'-nucleotidase
ZPR_3254	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
ZPR_3266	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3282	ENOG4105CMM	transposase
ZPR_3293	ENOG4107S1E	Beta-lactamase
ZPR_3303	ENOG4105D29	Helix-turn-helix type 11 domain protein
ZPR_3312	ENOG4105EKQ	RNA-directed DNA polymerase
ZPR_3325	ENOG4105M4P	Tetr family transcriptional regulator
ZPR_3328	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ZPR_3329	ENOG4105ID8	Transcriptional regulator, ARAC family
ZPR_3330	ENOG4105E1F	short-chain dehydrogenase reductase
ZPR_3341	ENOG4107QRI	Phosphoketolase
ZPR_3344	ENOG4108Z9Z	response to DNA damage stimulus
ZPR_3352	ENOG4107XVH	Transcriptional regulator
ZPR_3356	ENOG4105CMM	transposase
ZPR_3358	ENOG4105VPI	YqaE family transport protein
ZPR_3360	ENOG4108Z9Z	response to DNA damage stimulus
ZPR_3361	ENOG4107S5I	aldo keto reductase
ZPR_3364	ENOG4105BZU	Histidine kinase
ZPR_3370	ENOG4105C59	p-type ATPase
ZPR_3375	ENOG41080HT	Transcriptional regulator, arsr family
ZPR_3378	ENOG410624X	efflux transporter, rnd family, mfp subunit
ZPR_3384	ENOG4105E3B	Multicopper oxidase
ZPR_3386	ENOG4108IJF	Heavy metal efflux pump, CzcA
ZPR_3399	ENOG4105CUB	amino acid
ZPR_3401	ENOG4105EIE	fructose-bisphosphate aldolase
ZPR_3403	ENOG4108JSS	Haloalkane dehalogenase
ZPR_3404	ENOG4105CTQ	phosphohexokinase
ZPR_3405	ENOG4105C5I	Dehydrogenase
ZPR_3409	ENOG4105CY0	Metallo-Beta-Lactamase
ZPR_3410	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
ZPR_3411	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
ZPR_3425	ENOG4105Q33	Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency
ZPR_3431	ENOG4105DZR	Type I site-specific deoxyribonuclease
ZPR_3432	ENOG4105DFS	Conserved Protein
ZPR_3433	ENOG4105DB4	
ZPR_3434	ENOG4105EKX	Restriction modification system DNA (Specificity
ZPR_3435	ENOG4105CVR	type I restriction-modification system
ZPR_3443	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3447	ENOG4108W3Q	Transcriptional regulator
ZPR_3450	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ZPR_3470	ENOG4105CBG	Sulfatase
ZPR_3471	ENOG4105DYC	esterase
ZPR_3473	ENOG4105EBR	Carboxylesterase
ZPR_3474	ENOG4105DFY	n-acylglucosamine 2-epimerase
ZPR_3475	ENOG4105HY2	Glycosidase related protein
ZPR_3482	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3484	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3498	ENOG4105VC4	domain protein
ZPR_3499	ENOG4105KTH	gatB Yqey
ZPR_3503	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
ZPR_3504	ENOG4105CBG	Sulfatase
ZPR_3515	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
ZPR_3516	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
ZPR_3517	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
ZPR_3522	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
ZPR_3523	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
ZPR_3524	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
ZPR_3526	ENOG4105CHM	Aminotransferase
ZPR_3527	ENOG4105CQC	Prephenate dehydratase
ZPR_3528	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
ZPR_3529	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ZPR_3539	ENOG4107P26	
ZPR_3541	ENOG4105C9K	Endothelin-converting enzyme 1
ZPR_3545	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
ZPR_3548	ENOG4105DQ6	Transposase
ZPR_3552	ENOG4107RAN	Peptidase, M16
ZPR_3555	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3561	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
ZPR_3570	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
ZPR_3575	ENOG4105BZU	Histidine kinase
ZPR_3577	ENOG4105DY9	regulatoR
ZPR_3579	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ZPR_3580	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
ZPR_3583	ENOG4108URH	decarboxylase
ZPR_3584	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
ZPR_3585	ENOG4108MJ3	acetyltransferase
ZPR_3586	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
ZPR_3587	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
ZPR_3588	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
ZPR_3590	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
ZPR_3592	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
ZPR_3594	ENOG4105HHA	aminodeoxychorismate lyase
ZPR_3596	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
ZPR_3597	ENOG4105C0H	protease
ZPR_3602	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
ZPR_3603	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
ZPR_3604	ENOG4105E9K	Isocitrate dehydrogenase
ZPR_3605	ENOG4105C2C	drug resistance transporter, Bcr CflA
ZPR_3614	ENOG4105C22	threonyL-tRNA synthetase
ZPR_3615	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
ZPR_3617	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
ZPR_3619	ENOG4105CI3	gtp-binding protein typa
ZPR_3623	ENOG4105CFH	Aspartokinase
ZPR_3624	ENOG4105SYT	Methylenetetrahydrofolate reductase
ZPR_3625	ENOG4105C3R	Methionine synthase
ZPR_3626	ENOG4105C3R	Methionine synthase
ZPR_3627	ENOG4108UKZ	OsmC family
ZPR_3628	ENOG4105CAY	ferredoxin--nadp reductase
ZPR_3629	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
ZPR_3631	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
ZPR_3633	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
ZPR_3634	ENOG4105C28	cystathionine
ZPR_3636	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
ZPR_3639	ENOG4105C1G	acyl-Coa dehydrogenase
ZPR_3640	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
ZPR_3649	ENOG4105C26	Dehydrogenase
ZPR_3650	ENOG41075H3	AraC family transcriptional regulator
ZPR_3651	ENOG4105ZMH	deoxynucleoside kinase
ZPR_3654	ENOG4105DQE	DNA ligase
ZPR_3655	ENOG4105FDF	Could be involved in DNA repair (By similarity)
ZPR_3656	ENOG4105F0N	pyrophosphate phospho-hydrolase
ZPR_3658	ENOG4105CPP	Dehydrogenase, E1 component
ZPR_3660	ENOG4105C10	Electron transfer flavoprotein
ZPR_3662	ENOG4105D9N	nucleoside
ZPR_3665	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
ZPR_3674	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
ZPR_3675	ENOG4105FGM	Fructosamine kinase
ZPR_3677	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
ZPR_3684	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
ZPR_3685	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
ZPR_3690	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
ZPR_3694	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3697	ENOG4108UQS	dipeptidase
ZPR_3703	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
ZPR_3710	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
ZPR_3719	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ZPR_3722	ENOG4105DKW	ABC transporter
ZPR_3726	ENOG4105BZ1	(ABC) transporter
ZPR_3734	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
ZPR_3740	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
ZPR_3742	ENOG4105CHM	Aminotransferase
ZPR_3743	ENOG4107R0I	Cell wall formation (By similarity)
ZPR_3746	ENOG4107S6X	Glycosyl transferase, family 2
ZPR_3748	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
ZPR_3751	ENOG4105BZU	Histidine kinase
ZPR_3752	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
ZPR_3753	ENOG4105EGD	dinuclear metal center protein, YbgI family
ZPR_3756	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
ZPR_3757	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
ZPR_3758	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
ZPR_3762	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
ZPR_3763	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
ZPR_3764	ENOG4105CHR	reductase
ZPR_3767	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
ZPR_3769	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
ZPR_3770	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
ZPR_3777	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
ZPR_3778	ENOG4105CSV	Glutaminase
ZPR_3781	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
ZPR_3785	ENOG4105EUJ	GTP cyclohydrolase i
ZPR_3786	ENOG4105C8N	cysteinyl-tRNA synthetase
ZPR_3787	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
ZPR_3788	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
ZPR_3791	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
ZPR_3793	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
ZPR_3795	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
ZPR_3800	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
ZPR_3804	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
ZPR_3805	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
ZPR_3807	ENOG4105DFU	Cell wall formation (By similarity)
ZPR_3808	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
ZPR_3810	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
ZPR_3811	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
ZPR_3812	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
ZPR_3813	ENOG4105CJN	penicillin-binding protein
ZPR_3815	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
ZPR_3816	ENOG4107YM1	mraZ protein
ZPR_3818	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
ZPR_3823	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
ZPR_3824	ENOG4105WH1	Two component transcriptional regulator luxr family
ZPR_3825	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
ZPR_3830	ENOG4105FE9	pseudouridine synthase
ZPR_3835	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
ZPR_3837	ENOG4105C75	arginyL-tRNA synthetase
ZPR_3839	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
ZPR_3842	ENOG4105C94	Transporter
ZPR_3846	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
ZPR_3847	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
ZPR_3848	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
ZPR_3849	ENOG4108ZT0	50S ribosomal protein l17
ZPR_3850	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
ZPR_3851	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
ZPR_3852	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
ZPR_3853	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ZPR_3854	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
ZPR_3855	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
ZPR_3856	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
ZPR_3857	ENOG41084HK	50S ribosomal protein L30
ZPR_3858	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
ZPR_3859	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
ZPR_3860	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
ZPR_3861	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
ZPR_3862	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
ZPR_3863	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ZPR_3864	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
ZPR_3865	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
ZPR_3866	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
ZPR_3867	ENOG4105WNB	50s ribosomal protein l29
ZPR_3868	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
ZPR_3869	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
ZPR_3870	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
ZPR_3871	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
ZPR_3872	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ZPR_3873	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
ZPR_3874	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
ZPR_3875	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
ZPR_3876	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
ZPR_3877	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
ZPR_3878	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
ZPR_3879	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
ZPR_3880	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_3882	ENOG4105C2N	RNA methyltransferase TrmH family group 3
ZPR_3888	ENOG4105D1H	recombination factor protein RarA
ZPR_3892	ENOG4105W5Q	DNA repair protein (RadC
ZPR_3893	ENOG4105DFU	Cell wall formation (By similarity)
ZPR_3897	ENOG4105KCK	Peptidoglycan-associated lipoprotein
ZPR_3898	ENOG4107S85	alpha-2-macroglobulin domain protein
ZPR_3900	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ZPR_3901	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ZPR_3902	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
ZPR_3903	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
ZPR_3904	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
ZPR_3906	ENOG4105DGW	oligopeptidase A
ZPR_3910	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ZPR_3911	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ZPR_3915	ENOG4107R8N	Glycosyl transferase, family 2
ZPR_3918	ENOG4105DHJ	ABC, transporter
ZPR_3921	ENOG4108IXY	short-chain dehydrogenase reductase
ZPR_3925	ENOG4105KG3	cytidine deaminase
ZPR_3927	ENOG4105E6M	Sulphatase-modifying factor protein
ZPR_3928	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
ZPR_3931	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
ZPR_3933	ENOG4109015	Biopolymer transport protein exbD tolR
ZPR_3935	ENOG4105D82	Glutamate dehydrogenase
ZPR_3937	ENOG4105C1G	acyl-Coa dehydrogenase
ZPR_3942	ENOG4105KR8	Inherit from COG: Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
ZPR_3981	ENOG4105E5H	Transposase
ZPR_3982	ENOG4105EKQ	RNA-directed DNA polymerase
ZPR_4008	ENOG4105CB5	ATP-dependent DNA helicase recG
ZPR_4014	ENOG4105W5Q	DNA repair protein (RadC
ZPR_4015	ENOG4107XMK	single-stranded DNA-binding protein
ZPR_4033	ENOG4105D94	Major Facilitator Superfamily
ZPR_4047	ENOG4105DKB	L-sorbosone dehydrogenase
ZPR_4052	ENOG4108UDB	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
ZPR_4058	ENOG4107RY6	amino acid
ZPR_4061	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
ZPR_4063	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
ZPR_4064	ENOG4107QN2	dihydrolipoyl dehydrogenase
ZPR_4067	ENOG4105E3B	Multicopper oxidase
ZPR_4068	ENOG4105C59	p-type ATPase
ZPR_4071	ENOG4105FFC	UPF0187 protein
ZPR_4080	ENOG4108YZA	Nitrogen regulatory protein pii
ZPR_4093	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_4095	ENOG4107RAN	Peptidase, M16
ZPR_4097	ENOG4105T16	Transcriptional regulator (AraC family)
ZPR_4102	ENOG4108ETV	ABC transporter
ZPR_4106	ENOG4107KET	secretion protein, HlyD family
ZPR_4107	ENOG4105BZS	acriflavin resistance protein
ZPR_4109	ENOG4108Q35	Adenylate
ZPR_4122	ENOG4105CVR	type I restriction-modification system
ZPR_4133	ENOG4105W5Q	DNA repair protein (RadC
ZPR_4134	ENOG4108UUM	single-stranded DNA-binding protein
ZPR_4144	ENOG4105C5H	ABC transporter
ZPR_4146	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
ZPR_4150	ENOG4105E6M	Sulphatase-modifying factor protein
ZPR_4152	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
ZPR_4153	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
ZPR_4154	ENOG4108JU7	Transcriptional regulator
ZPR_4158	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
ZPR_4159	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
ZPR_4161	ENOG4106N3A	copper homeostasis protein cutc
ZPR_4168	ENOG4105C8P	)-transporter
ZPR_4173	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
ZPR_4176	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_4178	ENOG4105E2D	ec 3.2.1.52
ZPR_4179	ENOG4105CWX	Alpha-1,2-mannosidase
ZPR_4182	ENOG4105CKB	glycosidase
ZPR_4184	ENOG4105CWX	Alpha-1,2-mannosidase
ZPR_4186	ENOG4105DY9	regulatoR
ZPR_4187	ENOG4107XVH	Transcriptional regulator
ZPR_4191	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
ZPR_4192	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
ZPR_4195	ENOG4108IFG	nitrite reductase, (NAD(P)H)
ZPR_4198	ENOG4107XCH	Cyclase family
ZPR_4199	ENOG4106WTF	Glycosyl transferase, family 2
ZPR_4200	ENOG4105CND	Glycosyl transferase, family 2
ZPR_4207	ENOG4105FE9	pseudouridine synthase
ZPR_4211	ENOG4105KAV	tspo and mbr like protein
ZPR_4212	ENOG4105CBX	hi0933 family
ZPR_4214	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
ZPR_4215	ENOG410900G	Protein of unknown function (DUF421)
ZPR_4217	ENOG4105EE5	Membrane protein terC
ZPR_4221	ENOG4105E6M	Sulphatase-modifying factor protein
ZPR_4224	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_4227	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_4234	ENOG4105C59	p-type ATPase
ZPR_4235	ENOG41075H3	AraC family transcriptional regulator
ZPR_4240	ENOG4105C59	p-type ATPase
ZPR_4249	ENOG4105CBC	glutamate synthase
ZPR_4257	ENOG4105E3B	Multicopper oxidase
ZPR_4260	ENOG4108IJF	Heavy metal efflux pump, CzcA
ZPR_4275	ENOG4107Y80	Major Facilitator superfamily
ZPR_4284	ENOG4105FA0	parb-like partition protein
ZPR_4287	ENOG4105DR5	peptidase
ZPR_4291	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ZPR_4292	ENOG4105UNS	Pfam:DUF419
ZPR_4297	ENOG4105CSA	Coproporphyrinogen iii oxidase
ZPR_4298	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
ZPR_4302	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
ZPR_4304	ENOG4105CCN	Peptidase M56
ZPR_4309	ENOG4105BZU	Histidine kinase
ZPR_4311	ENOG41067MG	lrgb family
ZPR_4312	ENOG4105VAW	lrga family
ZPR_4314	ENOG4105E2D	ec 3.2.1.52
ZPR_4315	ENOG4105H3G	oxidoreductase
ZPR_4317	ENOG4107S2Z	UPF0761 membrane protein
ZPR_4322	ENOG4105EMU	Dehydrogenase
ZPR_4333	ENOG4105CNT	hydrolase family 2
ZPR_4336	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
ZPR_4338	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
ZPR_4343	ENOG4105BZU	Histidine kinase
ZPR_4346	ENOG4105D0S	secretion protein (HlyD
ZPR_4352	ENOG4108XM1	transcriptional regulator AsnC family
ZPR_4354	ENOG4108DBC	nitroreductase
ZPR_4358	ENOG4105QJH	Domain of unknown function (DUF718)
ZPR_4359	ENOG4105EDR	glucose galactose transporter
ZPR_4362	ENOG4105CPQ	Dehydrogenase
ZPR_4364	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
ZPR_4365	ENOG4105CF7	AraC family transcriptional regulator
ZPR_4366	ENOG4105DIA	mandelate racemase muconate lactonizing
ZPR_4368	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
ZPR_4369	ENOG4105ERH	Fumarylacetoacetate hydrolase
ZPR_4371	ENOG4105DTD	Dehydrogenase
ZPR_4383	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_4384	ENOG4105CWX	Alpha-1,2-mannosidase
ZPR_4385	ENOG4105FDP	GntR family transcriptional regulator
ZPR_4386	ENOG4105CBG	Sulfatase
ZPR_4389	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_4416	ENOG4105W5Q	DNA repair protein (RadC
ZPR_4417	ENOG4108UUM	single-stranded DNA-binding protein
ZPR_4424	ENOG4105VC4	domain protein
ZPR_4425	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
ZPR_4430	ENOG4105K63	Thioredoxin
ZPR_4431	ENOG4105C0B	DNA polymerase III (alpha subunit)
ZPR_4432	ENOG4108HRK	Histidine kinase
ZPR_4433	ENOG4108VAC	response regulator
ZPR_4435	ENOG4105K5M	30s ribosomal protein S16
ZPR_4436	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
ZPR_4437	ENOG4105C8T	Leucyl-tRNA synthetase
ZPR_4439	ENOG4107RJ9	Cell division protein FtsX
ZPR_4441	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
ZPR_4442	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
ZPR_4445	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
ZPR_4446	ENOG4105C09	Bile acid
ZPR_4447	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
ZPR_4449	ENOG4107XWI	flavin reductase domain protein, FMN-binding
ZPR_4450	ENOG4105GR3	Histidine kinase
ZPR_4453	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
ZPR_4456	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
ZPR_4458	ENOG4105BZU	Histidine kinase
ZPR_4459	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ZPR_4461	ENOG4108S2Y	peptide Chain Release factor
ZPR_4467	ENOG4105KVH	Transcriptional regulator
ZPR_4468	ENOG4105ECR	NmrA family
ZPR_4469	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
ZPR_4471	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
ZPR_4479	ENOG4105DY9	regulatoR
ZPR_4480	ENOG4105ENE	Histidine kinase
ZPR_4481	ENOG4105DY9	regulatoR
ZPR_4482	ENOG4105K46	50S ribosomal protein l27
ZPR_4483	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
ZPR_4489	ENOG4105C37	(CBS) domain
ZPR_4492	ENOG4105K70	DNA-binding protein
ZPR_4493	ENOG4105C03	ribonuclease
ZPR_4495	ENOG4105Y3E	Modulates RecA activity (By similarity)
ZPR_4499	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
ZPR_4500	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
ZPR_4501	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
ZPR_4502	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
ZPR_4503	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
ZPR_4504	ENOG4105KJM	monovalent cation h antiporter subunit g
ZPR_4505	ENOG4105W4C	monovalent cation H antiporter subunit F
ZPR_4506	ENOG4105SC1	monovalent cation H antiporter subunit E
ZPR_4507	ENOG4108JPZ	Monovalent cation H antiporter subunit D
ZPR_4508	ENOG4108ZE9	Monovalent cation H antiporter subunit C
ZPR_4509	ENOG4105HC0	Na H antiporter
ZPR_4510	ENOG4105D65	subunit l
ZPR_4512	ENOG4105VMP	Transcriptional regulator
ZPR_4514	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
ZPR_4515	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
ZPR_4516	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
ZPR_4518	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
ZPR_4519	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
ZPR_4520	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
ZPR_4523	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
ZPR_4527	ENOG4105CPC	Aldo Keto reductase
ZPR_4528	ENOG4105ER2	Ompa motb domain protein
ZPR_4529	ENOG4105CGK	Exodeoxyribonuclease III
ZPR_4532	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
ZPR_4533	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
ZPR_4536	ENOG4105C5S	asparaginyl-tRNA synthetase
ZPR_4538	ENOG4105C34	Pseudouridine synthase
ZPR_4539	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
ZPR_4543	ENOG4109015	Biopolymer transport protein exbD tolR
ZPR_4547	ENOG4105HDK	L-asparaginase
ZPR_4549	ENOG4105F8V	Hydrolase, tatD family
ZPR_4552	ENOG4105C7S	Dehydrogenase
ZPR_4553	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
ZPR_4561	ENOG4105C9M	aspartyl-trna synthetase
ZPR_4564	ENOG4105VEQ	Cold shock protein
ZPR_4565	ENOG4105EXW	epimerase dehydratase
ZPR_4568	ENOG4105C9K	Endothelin-converting enzyme 1
ZPR_4571	ENOG41080R2	UPF0102 protein
ZPR_4573	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
ZPR_4574	ENOG4105CMQ	Chloride channel
ZPR_4577	ENOG4105DGU	Histone deacetylase
ZPR_4579	ENOG4107QN1	sodium solute
ZPR_4580	ENOG4108UUM	single-stranded DNA-binding protein
ZPR_4587	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
ZPR_4596	ENOG4105W87	Cbs domain
ZPR_4599	ENOG4108JA2	transcriptioN-repair coupling factor
ZPR_4601	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
ZPR_4605	ENOG4105CPN	adenine deaminase
ZPR_4607	ENOG4108RG0	uracil-dna glycosylase
ZPR_4610	ENOG4107T8J	thymidine kinase
ZPR_4611	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
ZPR_4612	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
ZPR_4613	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
ZPR_4618	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
ZPR_4620	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
ZPR_4621	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
ZPR_4622	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
ZPR_4623	ENOG4105WXV	50S ribosomal protein L32
ZPR_4625	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
ZPR_4626	ENOG4108R6K	riboflavin synthase, subunit alpha
ZPR_4629	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
ZPR_4631	ENOG4105C19	ABC transporter
ZPR_4633	ENOG4107RBB	ABC transporter, permease
ZPR_4634	ENOG4107RBB	ABC transporter, permease
ZPR_4635	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ZPR_4637	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ZPR_4639	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ZPR_4640	ENOG4107RBB	ABC transporter, permease
ZPR_4641	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ZPR_4642	ENOG4107RBB	ABC transporter, permease
ZPR_4644	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
ZPR_4652	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_4655	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_4657	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
ZPR_4662	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_4664	ENOG4105C2F	Histidine kinase
ZPR_4665	ENOG4105DY9	regulatoR
ZPR_4669	ENOG4105EQR	Transposase IS116 IS110 IS902
ZPR_4672	ENOG4105DZR	Type I site-specific deoxyribonuclease
ZPR_4673	ENOG4105EKX	Restriction modification system DNA (Specificity
ZPR_4675	ENOG4105CVR	type I restriction-modification system
ZPR_4677	ENOG410756H	nucleotidyltransferase
ZPR_4679	ENOG4105DY9	regulatoR
ZPR_4680	ENOG4108HRK	Histidine kinase
ZPR_4684	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
ZPR_4689	ENOG4108ZVT	methylmalonyl-coA epimerase
ZPR_4690	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
ZPR_4691	ENOG4105D60	lipoprotein releasing system transmembrane protein
ZPR_4693	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
ZPR_4696	ENOG4105D17	glycoside hydrolase, family 3 domain protein
ZPR_4698	ENOG4105E2R	ROK family
ZPR_4699	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
ZPR_4703	ENOG4105C27	TonB-dependent Receptor Plug
ZPR_4704	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
ZPR_4705	ENOG4107SN7	NLP P60 protein
ZPR_4706	ENOG4105DTQ	mandelate racemase muconate lactonizing
ZPR_4707	ENOG4105F32	YngK protein
ZPR_4716	ENOG4105E98	transcriptional regulator DeoR family
ZPR_4717	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ZPR_4718	ENOG4105E2D	ec 3.2.1.52