locus-tag	class	description
PBT91_00010	COG3263	regulation of cellular component size
PBT91_00015	COG0217	transcriptional regulatory protein
PBT91_00020	COG0481	GTPase activity
PBT91_00030	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PBT91_00035	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
PBT91_00040	COG1349	DNA-binding transcription factor activity
PBT91_00045	COG1629	transport
PBT91_00055	COG1649	PFAM Uncharacterised BCR, COG1649
PBT91_00060	COG4948	Mandelate Racemase Muconate Lactonizing
PBT91_00065	COG0791	NLP P60 protein
PBT91_00070	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PBT91_00080	COG0405	Gamma-glutamyltransferase
PBT91_00085	COG4206	TonB-dependent receptor
PBT91_00085	COG1629	transport
PBT91_00095	COG0363	glucosamine-6-phosphate deaminase activity
PBT91_00105	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT91_00120	COG4591	ABC-type transport system involved in lipoprotein release permease component
PBT91_00125	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
PBT91_00130	COG0346	lactoylglutathione lyase activity
PBT91_00205	COG0629	single-stranded DNA binding
PBT91_00210	COG2003	Belongs to the UPF0758 family
PBT91_00230	COG3279	Response regulator of the LytR AlgR family
PBT91_00235	COG2972	Histidine kinase
PBT91_00245	COG4771	TonB-dependent receptor
PBT91_00265	COG3177	Filamentation induced by cAMP protein fic
PBT91_00280	COG4585	Histidine kinase
PBT91_00315	COG4974	Belongs to the 'phage' integrase family
PBT91_00335	COG3250	beta-galactosidase activity
PBT91_00340	COG0519	Catalyzes the synthesis of GMP from XMP
PBT91_00350	COG0577	efflux transmembrane transporter activity
PBT91_00350	COG1136	(ABC) transporter
PBT91_00355	COG0577	efflux transmembrane transporter activity
PBT91_00360	COG0577	efflux transmembrane transporter activity
PBT91_00360	COG1136	(ABC) transporter
PBT91_00375	COG0577	efflux transmembrane transporter activity
PBT91_00375	COG1136	(ABC) transporter
PBT91_00380	COG0577	efflux transmembrane transporter activity
PBT91_00380	COG1136	(ABC) transporter
PBT91_00385	COG1136	(ABC) transporter
PBT91_00415	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
PBT91_00425	COG0333	Belongs to the bacterial ribosomal protein bL32 family
PBT91_00430	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBT91_00435	COG0511	ligase activity, forming carbon-carbon bonds
PBT91_00440	COG0439	Biotin carboxylase
PBT91_00450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
PBT91_00465	COG3842	ATPase activity
PBT91_00470	COG1505	serine-type exopeptidase activity
PBT91_00475	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
PBT91_00480	COG1970	mechanosensitive ion channel activity
PBT91_00485	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
PBT91_00490	COG1435	thymidine kinase activity
PBT91_00500	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PBT91_00520	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
PBT91_00530	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
PBT91_00530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
PBT91_00540	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT91_00545	COG0720	synthase
PBT91_00555	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
PBT91_00565	COG0352	thiamine-phosphate diphosphorylase activity
PBT91_00570	COG2022	thiamine diphosphate biosynthetic process
PBT91_00575	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PBT91_00610	COG0534	Mate efflux family protein
PBT91_00650	COG1074	ATP-dependent DNA helicase activity
PBT91_00670	COG0328	RNA-DNA hybrid ribonuclease activity
PBT91_00680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
PBT91_00685	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PBT91_00690	COG0571	ribonuclease III activity
PBT91_00700	COG0469	pyruvate kinase activity
PBT91_00705	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PBT91_00715	COG2954	triphosphatase activity
PBT91_00725	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
PBT91_00740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT91_00755	COG1446	asparaginase
PBT91_00765	COG1012	belongs to the aldehyde dehydrogenase family
PBT91_00795	COG2824	Alkylphosphonate utilization operon protein PhnA
PBT91_00800	COG3279	Response regulator of the LytR AlgR family
PBT91_00825	COG3339	Conserved Protein
PBT91_00835	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
PBT91_00845	COG4221	oxidoreductase activity
PBT91_00855	COG0714	Associated with various cellular activities
PBT91_00870	COG2304	oxidoreductase activity
PBT91_00875	COG2304	oxidoreductase activity
PBT91_00900	COG0659	secondary active sulfate transmembrane transporter activity
PBT91_00905	COG0288	reversible hydration of carbon dioxide
PBT91_00925	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
PBT91_00940	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
PBT91_00945	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
PBT91_00950	COG0194	GDP metabolic process
PBT91_00955	COG1561	YicC-like family, N-terminal region
PBT91_00960	COG0429	hydrolase of the alpha beta-hydrolase fold
PBT91_00985	COG0626	cystathionine gamma-synthase activity
PBT91_00990	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
PBT91_01015	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PBT91_01020	COG3720	iron ion transport
PBT91_01025	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
PBT91_01030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBT91_01075	COG0590	tRNA wobble adenosine to inosine editing
PBT91_01080	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PBT91_01090	COG0232	Belongs to the dGTPase family. Type 2 subfamily
PBT91_01100	COG2095	MarC family integral membrane protein
PBT91_01120	COG0793	Belongs to the peptidase S41A family
PBT91_01140	COG4585	Histidine kinase
PBT91_01145	COG2197	response regulator
PBT91_01165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
PBT91_01170	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
PBT91_01175	COG0193	aminoacyl-tRNA hydrolase activity
PBT91_01180	COG0196	riboflavin kinase activity
PBT91_01190	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
PBT91_01210	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
PBT91_01215	COG2239	Acts as a magnesium transporter
PBT91_01220	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
PBT91_01225	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PBT91_01230	COG0702	epimerase
PBT91_01240	COG0527	aspartate kinase activity
PBT91_01255	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
PBT91_01270	COG1793	dna ligase
PBT91_01275	COG1201	RNA secondary structure unwinding
PBT91_01305	COG0423	glycine-tRNA ligase activity
PBT91_01310	COG1528	Iron-storage protein
PBT91_01320	COG1522	sequence-specific DNA binding
PBT91_01330	COG2363	Small membrane protein
PBT91_01335	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
PBT91_01350	COG0463	Glycosyl transferase, family 2
PBT91_01355	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PBT91_01370	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
PBT91_01390	COG4771	TonB-dependent receptor
PBT91_01395	COG0745	RESPONSE REGULATOR receiver
PBT91_01400	COG5002	protein histidine kinase activity
PBT91_01410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PBT91_01425	COG0489	protein tyrosine kinase activity
PBT91_01435	COG0492	ferredoxin-NADP+ reductase activity
PBT91_01450	COG1960	acyl-CoA dehydrogenase activity
PBT91_01455	COG0513	Belongs to the DEAD box helicase family
PBT91_01460	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
PBT91_01465	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
PBT91_01470	COG0052	Belongs to the universal ribosomal protein uS2 family
PBT91_01475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
PBT91_01480	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
PBT91_01500	COG1446	asparaginase
PBT91_01530	COG3273	potassium ion transport
PBT91_01530	COG0471	metal ion transport
PBT91_01555	COG0662	Cupin 2, conserved barrel domain protein
PBT91_01555	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
PBT91_01560	COG0529	Catalyzes the synthesis of activated sulfate
PBT91_01565	COG0175	sulfate reduction
PBT91_01580	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
PBT91_01585	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT91_01590	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
PBT91_01615	COG0110	maltose O-acetyltransferase activity
PBT91_01630	COG0297	glycogen (starch) synthase activity
PBT91_01635	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
PBT91_01650	COG0438	transferase activity, transferring glycosyl groups
PBT91_01695	COG0589	response to stress
PBT91_01700	COG0779	Required for maturation of 30S ribosomal subunits
PBT91_01705	COG2251	uridine kinase activity
PBT91_01705	COG0195	Participates in both transcription termination and antitermination
PBT91_01710	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
PBT91_01725	COG0437	4 iron, 4 sulfur cluster binding
PBT91_01730	COG0052	Belongs to the universal ribosomal protein uS2 family
PBT91_01755	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
PBT91_01760	COG2255	four-way junction helicase activity
PBT91_01765	COG2124	cytochrome p450
PBT91_01770	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
PBT91_01775	COG0281	malic enzyme
PBT91_01775	COG0280	phosphate acetyltransferase
PBT91_01780	COG0632	four-way junction helicase activity
PBT91_01790	COG0509	glycine decarboxylation via glycine cleavage system
PBT91_01810	COG0109	protoheme IX farnesyltransferase activity
PBT91_01815	COG1845	cytochrome c oxidase, subunit III
PBT91_01835	COG1999	signal sequence binding
PBT91_01840	COG2322	membrane
PBT91_01850	COG1136	(ABC) transporter
PBT91_01855	COG1136	(ABC) transporter
PBT91_01855	COG0577	efflux transmembrane transporter activity
PBT91_01860	COG0577	efflux transmembrane transporter activity
PBT91_01860	COG1136	(ABC) transporter
PBT91_01865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT91_01880	COG1214	PFAM Peptidase M22, glycoprotease
PBT91_01885	COG0668	transmembrane transport
PBT91_01890	COG1331	Highly conserved protein containing a thioredoxin domain
PBT91_01910	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
PBT91_01925	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
PBT91_01940	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
PBT91_01950	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
PBT91_01955	COG0596	Alpha beta hydrolase
PBT91_01975	COG0544	peptidyl-prolyl cis-trans isomerase activity
PBT91_01985	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
PBT91_01995	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT91_02000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBT91_02005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
PBT91_02010	COG0587	DNA-directed DNA polymerase activity
PBT91_02025	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
PBT91_02035	COG0457	Tetratricopeptide repeat
PBT91_02050	COG1253	flavin adenine dinucleotide binding
PBT91_02055	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PBT91_02070	COG1506	peptidase
PBT91_02070	COG0823	Involved in the tonB-independent uptake of proteins
PBT91_02075	COG3104	oligopeptide transport
PBT91_02085	COG2333	competence protein COMEC
PBT91_02085	COG0658	competence protein
PBT91_02090	COG0791	NLP P60 protein
PBT91_02095	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT91_02105	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
PBT91_02110	COG0793	Belongs to the peptidase S41A family
PBT91_02115	COG0772	Belongs to the SEDS family
PBT91_02120	COG0768	penicillin binding
PBT91_02135	COG1077	Cell shape determining protein MreB Mrl
PBT91_02140	COG0138	bifunctional purine biosynthesis protein purh
PBT91_02170	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
PBT91_02190	COG4977	sequence-specific DNA binding
PBT91_02190	COG1917	Cupin 2, conserved barrel domain protein
PBT91_02195	COG2217	Heavy metal translocating P-type atpase
PBT91_02200	COG0701	Predicted permease
PBT91_02215	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
PBT91_02220	COG0401	homolog of Blt101
PBT91_02225	COG0321	lipoyl(octanoyl) transferase activity
PBT91_02230	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
PBT91_02235	COG4771	TonB-dependent receptor
PBT91_02245	COG4771	TonB-dependent receptor
PBT91_02270	COG4771	TonB-dependent receptor
PBT91_02315	COG0070	glutamate synthase
PBT91_02315	COG0069	glutamate synthase activity
PBT91_02315	COG0067	glutamate synthase
PBT91_02320	COG1960	acyl-CoA dehydrogenase activity
PBT91_02325	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
PBT91_02330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PBT91_02335	COG0811	peptide transport
PBT91_02340	COG0848	biopolymer transport protein
PBT91_02350	COG0285	dihydrofolate synthase activity
PBT91_02365	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
PBT91_02370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT91_02380	COG0295	cytidine deaminase activity
PBT91_02385	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
PBT91_02415	COG1127	ABC transporter
PBT91_02420	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
PBT91_02430	COG1215	transferase activity, transferring glycosyl groups
PBT91_02445	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PBT91_02445	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
PBT91_02465	COG0339	signal peptide processing
PBT91_02470	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
PBT91_02475	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
PBT91_02485	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
PBT91_02515	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PBT91_02520	COG2003	Belongs to the UPF0758 family
PBT91_02540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
PBT91_02550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBT91_02565	COG4771	TonB-dependent receptor
PBT91_02580	COG4771	TonB-dependent receptor
PBT91_02585	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
PBT91_02590	COG0049	tRNA binding
PBT91_02595	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
PBT91_02600	COG0051	transcription antitermination factor activity, RNA binding
PBT91_02605	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
PBT91_02610	COG0088	Forms part of the polypeptide exit tunnel
PBT91_02615	COG0089	rRNA binding
PBT91_02620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
PBT91_02625	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
PBT91_02630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
PBT91_02635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
PBT91_02640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
PBT91_02645	COG0255	Belongs to the universal ribosomal protein uL29 family
PBT91_02650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
PBT91_02655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
PBT91_02660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
PBT91_02665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
PBT91_02670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
PBT91_02675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
PBT91_02680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
PBT91_02685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
PBT91_02690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
PBT91_02695	COG1841	ribosomal large subunit assembly
PBT91_02700	COG0200	Binds to the 23S rRNA
PBT91_02710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
PBT91_02715	COG0257	Belongs to the bacterial ribosomal protein bL36 family
PBT91_02720	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
PBT91_02725	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
PBT91_02730	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
PBT91_02735	COG0202	RNA polymerase activity
PBT91_02740	COG0203	ribosomal protein L17
PBT91_02745	COG0505	Belongs to the CarA family
PBT91_02750	COG0148	phosphopyruvate hydratase activity
PBT91_02755	COG0297	glycogen (starch) synthase activity
PBT91_02765	COG1834	amidinotransferase
PBT91_02775	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
PBT91_02780	COG1090	epimerase
PBT91_02790	COG2095	MarC family integral membrane protein
PBT91_02800	COG0018	arginyl-trna synthetase
PBT91_02805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
PBT91_02815	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
PBT91_02820	COG3339	Conserved Protein
PBT91_02860	COG0358	DNA primase activity
PBT91_02865	COG2197	response regulator
PBT91_02870	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
PBT91_02890	COG0218	Necessary for normal cell division and for the maintenance of normal septation
PBT91_02895	COG2267	carboxylic ester hydrolase activity
PBT91_02900	COG2001	Belongs to the MraZ family
PBT91_02905	COG0275	rRNA processing
PBT91_02920	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
PBT91_02925	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
PBT91_02930	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
PBT91_02940	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
PBT91_02945	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
PBT91_02960	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
PBT91_02965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PBT91_02975	COG1619	proteins homologs of microcin C7 resistance protein MccF
PBT91_02985	COG0602	queuosine metabolic process
PBT91_02995	COG0187	DNA topoisomerase II activity
PBT91_03005	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PBT91_03015	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
PBT91_03020	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
PBT91_03025	COG0215	cysteine-tRNA ligase activity
PBT91_03030	COG0302	gtp cyclohydrolase
PBT91_03050	COG0442	prolyl-tRNA aminoacylation
PBT91_03065	COG0268	Binds directly to 16S ribosomal RNA
PBT91_03070	COG2066	Belongs to the glutaminase family
PBT91_03075	COG3340	Belongs to the peptidase S51 family
PBT91_03110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PBT91_03115	COG0671	phosphoesterase, PA-phosphatase related
PBT91_03125	COG3844	kynureninase activity
PBT91_03145	COG3046	protein related to deoxyribodipyrimidine photolyase
PBT91_03150	COG0415	Belongs to the DNA photolyase family
PBT91_03170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
PBT91_03175	COG3263	regulation of cellular component size
PBT91_03195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
PBT91_03200	COG1663	tetraacyldisaccharide 4'-kinase activity
PBT91_03210	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PBT91_03215	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
PBT91_03240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
PBT91_03245	COG0436	Aminotransferase
PBT91_03255	COG0525	valine-tRNA ligase activity
PBT91_03265	COG0688	phosphatidylethanolamine metabolic process
PBT91_03270	COG4589	Belongs to the CDS family
PBT91_03280	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PBT91_03285	COG0799	negative regulation of ribosome biogenesis
PBT91_03300	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
PBT91_03305	COG1051	belongs to the nudix hydrolase family
PBT91_03335	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
PBT91_03345	COG1181	Belongs to the D-alanine--D-alanine ligase family
PBT91_03355	COG0564	pseudouridine synthase activity
PBT91_03360	COG3022	response to hydroperoxide
PBT91_03385	COG0159	tryptophan synthase activity
PBT91_03390	COG0133	tryptophan synthase activity
PBT91_03395	COG0135	phosphoribosylanthranilate isomerase activity
PBT91_03400	COG0134	indole-3-glycerol-phosphate synthase activity
PBT91_03405	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PBT91_03410	COG0512	Glutamine amidotransferase of anthranilate synthase
PBT91_03410	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
PBT91_03415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PBT91_03425	COG0778	Nitroreductase
PBT91_03435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBT91_03440	COG1054	Belongs to the UPF0176 family
PBT91_03450	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
PBT91_03455	COG0291	Belongs to the bacterial ribosomal protein bL35 family
PBT91_03460	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
PBT91_03465	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
PBT91_03530	COG2814	Major facilitator Superfamily
PBT91_03540	COG0335	large ribosomal subunit rRNA binding
PBT91_03545	COG0336	Belongs to the RNA methyltransferase TrmD family
PBT91_03555	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
PBT91_03560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
PBT91_03570	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
PBT91_03580	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
PBT91_03585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
PBT91_03590	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
PBT91_03595	COG0824	Thioesterase
PBT91_03600	COG1739	Uncharacterized protein family UPF0029
PBT91_03610	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PBT91_03610	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
PBT91_03620	COG2890	protein-(glutamine-N5) methyltransferase activity
PBT91_03625	COG1611	Belongs to the LOG family
PBT91_03640	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBT91_03645	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBT91_03655	COG3279	Response regulator of the LytR AlgR family
PBT91_03665	COG5002	protein histidine kinase activity
PBT91_03675	COG4251	negative regulation of phosphorylation
PBT91_03685	COG0784	Response regulator, receiver
PBT91_03705	COG1309	transcriptional regulator
PBT91_03730	COG2327	Polysaccharide pyruvyl transferase
PBT91_03745	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
PBT91_03770	COG0438	transferase activity, transferring glycosyl groups
PBT91_03785	COG0438	transferase activity, transferring glycosyl groups
PBT91_03795	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT91_03800	COG1216	Glycosyl transferase, family 2
PBT91_03820	COG4771	TonB-dependent receptor
PBT91_03850	COG0745	RESPONSE REGULATOR receiver
PBT91_03850	COG2205	protein histidine kinase activity
PBT91_03850	COG3292	Two component regulator propeller
PBT91_03880	COG3590	peptidase
PBT91_03935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT91_03940	COG2877	3-deoxy-8-phosphooctulonate synthase activity
PBT91_03945	COG1217	gtp-binding protein TYPA
PBT91_03980	COG2884	Cell division ATP-binding protein ftsE
PBT91_04000	COG1574	metal-dependent hydrolase with the TIM-barrel fold
PBT91_04005	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBT91_04010	COG0450	alkyl hydroperoxide reductase
PBT91_04020	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBT91_04025	COG0569	domain protein
PBT91_04030	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PBT91_04045	COG1132	(ABC) transporter
PBT91_04055	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PBT91_04065	COG1862	Preprotein translocase
PBT91_04070	COG2195	Cleaves the N-terminal amino acid of tripeptides
PBT91_04075	COG0167	dihydroorotate dehydrogenase activity
PBT91_04095	COG0516	GMP reductase activity
PBT91_04095	COG0517	IMP dehydrogenase activity
PBT91_04110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
PBT91_04115	COG0714	Associated with various cellular activities
PBT91_04120	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
PBT91_04125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT91_04145	COG1233	COG1233 Phytoene dehydrogenase and related
PBT91_04155	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
PBT91_04165	COG0019	diaminopimelate decarboxylase activity
PBT91_04185	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
PBT91_04190	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PBT91_04195	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
PBT91_04210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
PBT91_04220	COG0343	queuine tRNA-ribosyltransferase activity
PBT91_04230	COG0825	malonyl-CoA metabolic process
PBT91_04235	COG0305	Participates in initiation and elongation during chromosome replication
PBT91_04245	COG0432	Pfam Uncharacterised protein family UPF0047
PBT91_04250	COG0657	acetylesterase activity
PBT91_04255	COG4677	pectinesterase activity
PBT91_04260	COG3292	Two component regulator propeller
PBT91_04260	COG2205	protein histidine kinase activity
PBT91_04260	COG0745	RESPONSE REGULATOR receiver
PBT91_04265	COG1629	transport
PBT91_04280	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
PBT91_04285	COG3250	beta-galactosidase activity
PBT91_04325	COG2814	Major facilitator Superfamily
PBT91_04340	COG0492	ferredoxin-NADP+ reductase activity
PBT91_04345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
PBT91_04350	COG0095	Lipoate-protein ligase
PBT91_04360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
PBT91_04365	COG1185	polyribonucleotide nucleotidyltransferase activity
PBT91_04370	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
PBT91_04375	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
PBT91_04380	COG0191	fructose-bisphosphate aldolase activity
PBT91_04390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBT91_04400	COG2226	methyltransferase
PBT91_04405	COG0569	domain protein
PBT91_04410	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PBT91_04415	COG0436	Aminotransferase
PBT91_04420	COG3239	Fatty acid desaturase
PBT91_04425	COG0357	Ribosomal RNA small subunit methyltransferase G
PBT91_04435	COG1012	belongs to the aldehyde dehydrogenase family
PBT91_04445	COG2967	ApaG domain
PBT91_04460	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PBT91_04465	COG1805	sodium ion transport
PBT91_04475	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PBT91_04480	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
PBT91_04495	COG1477	protein flavinylation
PBT91_04520	COG3118	belongs to the thioredoxin family
PBT91_04525	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
PBT91_04540	COG0740	serine-type endopeptidase activity
PBT91_04550	COG5002	protein histidine kinase activity
PBT91_04555	COG0745	RESPONSE REGULATOR receiver
PBT91_04575	COG0101	tRNA pseudouridine synthase activity
PBT91_04580	COG1132	(ABC) transporter
PBT91_04595	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
PBT91_04600	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
PBT91_04615	COG0149	triose-phosphate isomerase activity
PBT91_04620	COG2264	protein methyltransferase activity
PBT91_04635	COG3152	Membrane
PBT91_04640	COG2076	Multidrug Resistance protein
PBT91_04645	COG1785	Belongs to the alkaline phosphatase family
PBT91_04655	COG0523	cobalamin synthesis protein
PBT91_04670	COG4771	TonB-dependent receptor
PBT91_04680	COG0386	Belongs to the glutathione peroxidase family
PBT91_04715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT91_04730	COG2814	Major facilitator Superfamily
PBT91_04780	COG0174	glutamine synthetase
PBT91_04790	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
PBT91_04800	COG1131	(ABC) transporter
PBT91_04805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
PBT91_04810	COG0284	orotidine-5'-phosphate decarboxylase activity
PBT91_04815	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
PBT91_04830	COG0788	formyltetrahydrofolate deformylase activity
PBT91_04835	COG1703	isobutyryl-CoA mutase activity
PBT91_04835	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT91_04835	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT91_04840	COG2095	MarC family integral membrane protein
PBT91_04850	COG1522	sequence-specific DNA binding
PBT91_04880	COG0004	ammonium transporteR
PBT91_04885	COG0347	Belongs to the P(II) protein family
PBT91_04890	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
PBT91_04925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
PBT91_04925	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
PBT91_04940	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
PBT91_04945	COG0484	heat shock protein binding
PBT91_04950	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
PBT91_04955	COG4152	abc transporter atp-binding protein
PBT91_04960	COG1668	transmembrane transport
PBT91_04965	COG3264	Mechanosensitive ion channel
PBT91_04965	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
PBT91_04975	COG2204	response regulator
PBT91_04985	COG0556	nucleotide-excision repair
PBT91_05025	COG0517	IMP dehydrogenase activity
PBT91_05025	COG0617	tRNA 3'-terminal CCA addition
PBT91_05025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PBT91_05030	COG0009	L-threonylcarbamoyladenylate synthase
PBT91_05035	COG1216	Glycosyl transferase, family 2
PBT91_05060	COG2171	N-acyltransferase activity
PBT91_05065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
PBT91_05070	COG0242	peptide deformylase activity
PBT91_05085	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
PBT91_05100	COG4106	trans-aconitate 2-methyltransferase activity
PBT91_05105	COG1012	belongs to the aldehyde dehydrogenase family
PBT91_05125	COG0542	response to heat
PBT91_05130	COG3118	belongs to the thioredoxin family
PBT91_05145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
PBT91_05180	COG0300	oxidoreductase activity
PBT91_05185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
PBT91_05195	COG0488	(ABC) transporter
PBT91_05215	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
PBT91_05220	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT91_05225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
PBT91_05235	COG0179	Fumarylacetoacetate (FAA) hydrolase
PBT91_05245	COG1546	Belongs to the CinA family
PBT91_05245	COG1058	Belongs to the CinA family
PBT91_05250	COG0227	Belongs to the bacterial ribosomal protein bL28 family
PBT91_05255	COG0267	Belongs to the bacterial ribosomal protein bL33 family
PBT91_05265	COG0552	protein localization to endoplasmic reticulum
PBT91_05270	COG0154	amidase activity
PBT91_05290	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBT91_05315	COG0656	L-ascorbic acid biosynthetic process
PBT91_05325	COG4974	Belongs to the 'phage' integrase family
PBT91_05330	COG4974	Belongs to the 'phage' integrase family
PBT91_05365	COG1629	transport
PBT91_05370	COG0702	epimerase
PBT91_05415	COG4771	TonB-dependent receptor
PBT91_05420	COG0702	epimerase
PBT91_05450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
PBT91_05465	COG4771	TonB-dependent receptor
PBT91_05480	COG0612	Peptidase, M16
PBT91_05550	COG5002	protein histidine kinase activity
PBT91_05555	COG0745	RESPONSE REGULATOR receiver
PBT91_05560	COG0629	single-stranded DNA binding
PBT91_05565	COG2003	Belongs to the UPF0758 family
PBT91_05585	COG0038	chloride channel
PBT91_05595	COG2814	Major facilitator Superfamily
PBT91_05615	COG0517	IMP dehydrogenase activity
PBT91_05630	COG0640	Transcriptional regulator
PBT91_05640	COG4974	Belongs to the 'phage' integrase family
PBT91_05645	COG0517	IMP dehydrogenase activity
PBT91_05700	COG4974	Belongs to the 'phage' integrase family
PBT91_05705	COG0517	IMP dehydrogenase activity
PBT91_05760	COG4974	Belongs to the 'phage' integrase family
PBT91_05775	COG4974	Belongs to the 'phage' integrase family
PBT91_05875	COG5002	protein histidine kinase activity
PBT91_05890	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PBT91_05895	COG0569	domain protein
PBT91_05900	COG3850	Histidine kinase
PBT91_05905	COG2197	response regulator
PBT91_05935	COG1858	cytochrome C peroxidase
PBT91_05940	COG3608	succinylglutamate desuccinylase aspartoacylase
PBT91_05950	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PBT91_05950	COG2755	lipolytic protein G-D-S-L family
PBT91_05975	COG1132	(ABC) transporter
PBT91_05990	COG1272	protein, Hemolysin III
PBT91_06000	COG0419	ATPase involved in DNA repair
PBT91_06005	COG0420	3'-5' exonuclease activity
PBT91_06010	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PBT91_06030	COG0561	phosphatase activity
PBT91_06035	COG4771	TonB-dependent receptor
PBT91_06050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PBT91_06050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
PBT91_06065	COG1674	ftsk spoiiie
PBT91_06070	COG0596	Alpha beta hydrolase
PBT91_06090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT91_06095	COG0450	alkyl hydroperoxide reductase
PBT91_06100	COG1757	Na H antiporter
PBT91_06105	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBT91_06115	COG0513	Belongs to the DEAD box helicase family
PBT91_06130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
PBT91_06135	COG0037	tRNA processing
PBT91_06160	COG1085	galactose-1-phosphate uridylyltransferase
PBT91_06165	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
PBT91_06205	COG0561	phosphatase activity
PBT91_06210	COG4206	TonB-dependent receptor
PBT91_06210	COG1629	transport
PBT91_06225	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
PBT91_06230	COG1554	hydrolase, family 65, central catalytic
PBT91_06235	COG1082	Xylose isomerase domain protein TIM barrel
PBT91_06240	COG0366	Alpha amylase catalytic
PBT91_06245	COG0205	6-phosphofructokinase activity
PBT91_06250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
PBT91_06260	COG0606	chelatase, subunit chli
PBT91_06270	COG1914	H( )-stimulated, divalent metal cation uptake system
PBT91_06280	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
PBT91_06285	COG1984	allophanate hydrolase subunit 2
PBT91_06295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
PBT91_06295	COG3153	acetyltransferase
PBT91_06305	COG0028	Belongs to the TPP enzyme family
PBT91_06315	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
PBT91_06320	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PBT91_06330	COG0137	argininosuccinate synthase activity
PBT91_06335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
PBT91_06340	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PBT91_06345	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBT91_06350	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
PBT91_06355	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
PBT91_06360	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PBT91_06365	COG0165	Argininosuccinate lyase
PBT91_06380	COG0473	3-isopropylmalate dehydrogenase activity
PBT91_06385	COG0066	3-isopropylmalate dehydratase activity
PBT91_06390	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
PBT91_06395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
PBT91_06410	COG3387	PFAM Glycoside hydrolase 15-related
PBT91_06415	COG2321	neutral zinc metallopeptidase
PBT91_06430	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
PBT91_06445	COG1760	l-serine dehydratase
PBT91_06450	COG0443	Heat shock 70 kDa protein
PBT91_06480	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
PBT91_06495	COG2996	Protein conserved in bacteria
PBT91_06535	COG0022	dehydrogenase e1 component
PBT91_06545	COG1611	Belongs to the LOG family
PBT91_06550	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PBT91_06560	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PBT91_06585	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT91_06610	COG0668	transmembrane transport
PBT91_06615	COG0783	Belongs to the Dps family
PBT91_06635	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT91_06640	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
PBT91_06645	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PBT91_06650	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
PBT91_06655	COG1086	Polysaccharide biosynthesis protein
PBT91_06670	COG0643	Histidine kinase
PBT91_06670	COG2198	Histidine kinase
PBT91_06670	COG0784	Response regulator, receiver
PBT91_06690	COG0527	aspartate kinase activity
PBT91_06690	COG0460	homoserine dehydrogenase
PBT91_06695	COG0083	homoserine kinase activity
PBT91_06700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
PBT91_06715	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
PBT91_06720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
PBT91_06720	COG4651	solute:proton antiporter activity
PBT91_06730	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
PBT91_06735	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
PBT91_06740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
PBT91_06750	COG4251	negative regulation of phosphorylation
PBT91_06765	COG1187	pseudouridine synthase activity
PBT91_06785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT91_06800	COG0339	signal peptide processing
PBT91_06815	COG2084	Dehydrogenase
PBT91_06845	COG1215	transferase activity, transferring glycosyl groups
PBT91_06865	COG3278	Belongs to the heme-copper respiratory oxidase family
PBT91_06895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PBT91_06905	COG0738	Major facilitator superfamily
PBT91_06930	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PBT91_07000	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
PBT91_07060	COG1629	transport
PBT91_07060	COG4206	TonB-dependent receptor
PBT91_07085	COG4181	ATPase activity
PBT91_07115	COG3279	Response regulator of the LytR AlgR family
PBT91_07160	COG4771	TonB-dependent receptor
PBT91_07170	COG4206	TonB-dependent receptor
PBT91_07170	COG1629	transport
PBT91_07180	COG1785	Belongs to the alkaline phosphatase family
PBT91_07210	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
PBT91_07215	COG0351	phosphomethylpyrimidine kinase
PBT91_07220	COG0352	thiamine-phosphate diphosphorylase activity
PBT91_07225	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
PBT91_07240	COG1733	regulation of RNA biosynthetic process
PBT91_07255	COG0730	response to heat
PBT91_07260	COG1271	oxidase subunit
PBT91_07270	COG3940	Belongs to the glycosyl hydrolase 43 family
PBT91_07275	COG1476	TRANSCRIPTIONal
PBT91_07290	COG4771	TonB-dependent receptor
PBT91_07315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBT91_07325	COG0439	Biotin carboxylase
PBT91_07330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PBT91_07350	COG2860	membrane
PBT91_07355	COG0492	ferredoxin-NADP+ reductase activity
PBT91_07420	COG0714	Associated with various cellular activities
PBT91_07450	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBT91_07455	COG0494	nUDIX hydrolase
PBT91_07480	COG4206	TonB-dependent receptor
PBT91_07480	COG1629	transport
PBT91_07490	COG3275	phosphorelay sensor kinase activity
PBT91_07505	COG3279	Response regulator of the LytR AlgR family
PBT91_07515	COG1595	DNA-templated transcription, initiation
PBT91_07530	COG0673	inositol 2-dehydrogenase activity
PBT91_07535	COG2211	Major facilitator Superfamily
PBT91_07575	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PBT91_07580	COG4771	TonB-dependent receptor
PBT91_07585	COG1597	lipid kinase activity
PBT91_07620	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
PBT91_07625	COG3387	PFAM Glycoside hydrolase 15-related
PBT91_07640	COG1960	acyl-CoA dehydrogenase activity
PBT91_07650	COG0183	Belongs to the thiolase family
PBT91_07660	COG1250	3-hydroxyacyl-CoA dehydrogenase
PBT91_07660	COG1024	Enoyl-CoA hydratase
PBT91_07665	COG1846	Transcriptional regulator
PBT91_07670	COG1022	Amp-dependent synthetase and ligase
PBT91_07680	COG0047	phosphoribosylformylglycinamidine synthase activity
PBT91_07680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
PBT91_07685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
PBT91_07685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
PBT91_07710	COG1132	(ABC) transporter
PBT91_07715	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
PBT91_07720	COG0463	Glycosyl transferase, family 2
PBT91_07730	COG0254	rRNA binding
PBT91_07755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBT91_07765	COG1741	Belongs to the pirin family
PBT91_07780	COG2234	aminopeptidase activity
PBT91_07795	COG0230	Belongs to the bacterial ribosomal protein bL34 family
PBT91_07800	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
PBT91_07805	COG2363	Small membrane protein
PBT91_07820	COG1607	acyl-coa hydrolase
PBT91_07830	COG1322	Protein conserved in bacteria
PBT91_07840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
PBT91_07850	COG4206	TonB-dependent receptor
PBT91_07895	COG4206	TonB-dependent receptor
PBT91_07895	COG1629	transport
PBT91_07900	COG2936	dipeptidyl-peptidase activity
PBT91_07910	COG1045	serine acetyltransferase
PBT91_07950	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
PBT91_07960	COG0069	glutamate synthase activity
PBT91_07965	COG0589	response to stress
PBT91_07985	COG1396	sequence-specific DNA binding
PBT91_07995	COG1842	Phage shock protein A
PBT91_08035	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
PBT91_08045	COG0670	Belongs to the BI1 family
PBT91_08060	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
PBT91_08085	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
PBT91_08090	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
PBT91_08100	COG1295	ribonuclease BN
PBT91_08115	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
PBT91_08120	COG3279	Response regulator of the LytR AlgR family
PBT91_08125	COG0360	Binds together with S18 to 16S ribosomal RNA
PBT91_08130	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
PBT91_08135	COG0359	binds to the 23S rRNA
PBT91_08145	COG0577	efflux transmembrane transporter activity
PBT91_08150	COG0124	histidyl-tRNA synthetase
PBT91_08160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBT91_08190	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PBT91_08225	COG0739	heme binding
PBT91_08230	COG4974	Belongs to the 'phage' integrase family
PBT91_08285	COG3239	Fatty acid desaturase
PBT91_08295	COG4974	Belongs to the 'phage' integrase family
PBT91_08315	COG2986	histidine ammonia-lyase
PBT91_08320	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_08355	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PBT91_08380	COG1215	transferase activity, transferring glycosyl groups
PBT91_08425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
PBT91_08430	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
PBT91_08440	COG0205	6-phosphofructokinase activity
PBT91_08445	COG1803	Methylglyoxal synthase
PBT91_08455	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
PBT91_08465	COG0667	Aldo Keto reductase
PBT91_08470	COG0251	oxidation-reduction process
PBT91_08480	COG0860	N-Acetylmuramoyl-L-alanine amidase
PBT91_08490	COG0247	lactate metabolic process
PBT91_08490	COG2181	nitrate reductase activity
PBT91_08495	COG0247	lactate metabolic process
PBT91_08495	COG2181	nitrate reductase activity
PBT91_08505	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT91_08510	COG0438	transferase activity, transferring glycosyl groups
PBT91_08520	COG0247	lactate metabolic process
PBT91_08535	COG3537	Alpha-1,2-mannosidase
PBT91_08550	COG2226	methyltransferase
PBT91_08580	COG1970	mechanosensitive ion channel activity
PBT91_08600	COG1522	sequence-specific DNA binding
PBT91_08605	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
PBT91_08620	COG0693	protein deglycase activity
PBT91_08630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
PBT91_08645	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
PBT91_08665	COG3011	Protein conserved in bacteria
PBT91_08670	COG1193	negative regulation of DNA recombination
PBT91_08675	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
PBT91_08700	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PBT91_08705	COG0813	purine-nucleoside phosphorylase activity
PBT91_08715	COG0023	Translation Initiation Factor
PBT91_08725	COG0022	dehydrogenase e1 component
PBT91_08775	COG1278	Cold shock
PBT91_08780	COG2723	6-phospho-beta-galactosidase activity
PBT91_08795	COG3384	dioxygenase
PBT91_08800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
PBT91_08810	COG0363	glucosamine-6-phosphate deaminase activity
PBT91_08815	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
PBT91_08820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
PBT91_08825	COG0698	ribose 5-phosphate isomerase
PBT91_08830	COG2855	membrane
PBT91_08835	COG0583	DNA-binding transcription factor activity
PBT91_08865	COG1902	pentaerythritol trinitrate reductase activity
PBT91_08875	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PBT91_08890	COG1289	transmembrane transporter activity
PBT91_08895	COG2130	NADP-dependent
PBT91_08900	COG4221	oxidoreductase activity
PBT91_08905	COG2072	flavoprotein involved in K transport
PBT91_08935	COG0401	homolog of Blt101
PBT91_08945	COG2814	Major facilitator Superfamily
PBT91_08950	COG0668	transmembrane transport
PBT91_08960	COG0668	transmembrane transport
PBT91_08965	COG1607	acyl-coa hydrolase
PBT91_08970	COG1051	belongs to the nudix hydrolase family
PBT91_08980	COG1012	belongs to the aldehyde dehydrogenase family
PBT91_09010	COG0183	Belongs to the thiolase family
PBT91_09020	COG3063	Type IV pilus biogenesis stability protein PilW
PBT91_09025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
PBT91_09030	COG0542	response to heat
PBT91_09035	COG2986	histidine ammonia-lyase
PBT91_09040	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
PBT91_09040	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
PBT91_09045	COG0404	The glycine cleavage system catalyzes the degradation of glycine
PBT91_09055	COG2154	pterin-4-alpha-carbinolamine dehydratase
PBT91_09060	COG0217	transcriptional regulatory protein
PBT91_09070	COG3265	gluconokinase activity
PBT91_09075	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PBT91_09085	COG0527	aspartate kinase activity
PBT91_09110	COG1047	Peptidyl-prolyl cis-trans
PBT91_09115	COG1764	response to oxidative stress
PBT91_09125	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
PBT91_09165	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PBT91_09195	COG1506	peptidase
PBT91_09195	COG0823	Involved in the tonB-independent uptake of proteins
PBT91_09200	COG0561	phosphatase activity
PBT91_09205	COG1629	transport
PBT91_09205	COG4206	TonB-dependent receptor
PBT91_09215	COG3938	Belongs to the proline racemase family
PBT91_09225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBT91_09230	COG2207	Transcriptional regulator
PBT91_09240	COG3250	beta-galactosidase activity
PBT91_09245	COG0006	proline dipeptidase activity
PBT91_09260	COG1858	cytochrome C peroxidase
PBT91_09295	COG1482	cell wall glycoprotein biosynthetic process
PBT91_09305	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_09310	COG4974	Belongs to the 'phage' integrase family
PBT91_09330	COG0517	IMP dehydrogenase activity
PBT91_09335	COG4974	Belongs to the 'phage' integrase family
PBT91_09395	COG0517	IMP dehydrogenase activity
PBT91_09400	COG4974	Belongs to the 'phage' integrase family
PBT91_09435	COG1131	(ABC) transporter
PBT91_09460	COG2160	L-arabinose isomerase activity
PBT91_09465	COG0235	Class ii aldolase
PBT91_09475	COG3940	Belongs to the glycosyl hydrolase 43 family
PBT91_09480	COG3507	Belongs to the glycosyl hydrolase 43 family
PBT91_09485	COG3507	Belongs to the glycosyl hydrolase 43 family
PBT91_09495	COG3507	Belongs to the glycosyl hydrolase 43 family
PBT91_09500	COG3534	alpha-L-arabinofuranosidase
PBT91_09505	COG0702	epimerase
PBT91_09510	COG1629	transport
PBT91_09530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
PBT91_09540	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
PBT91_09545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PBT91_09570	COG4771	TonB-dependent receptor
PBT91_09580	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBT91_09585	COG1136	(ABC) transporter
PBT91_09605	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
PBT91_09620	COG0280	phosphate acetyltransferase
PBT91_09620	COG0857	belongs to the CobB CobQ family
PBT91_09625	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
PBT91_09640	COG0321	lipoyl(octanoyl) transferase activity
PBT91_09640	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
PBT91_09650	COG4774	siderophore transport
PBT91_09660	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
PBT91_09680	COG0514	ATP-dependent DNA helicase (RecQ)
PBT91_09685	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
PBT91_09695	COG1678	Uncharacterized ACR, COG1678
PBT91_09725	COG0438	transferase activity, transferring glycosyl groups
PBT91_09745	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
PBT91_09765	COG4974	Belongs to the 'phage' integrase family
PBT91_09780	COG4974	Belongs to the 'phage' integrase family
PBT91_09790	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_09795	COG1733	regulation of RNA biosynthetic process
PBT91_09810	COG1994	Peptidase M50
PBT91_09825	COG0629	single-stranded DNA binding
PBT91_09830	COG2003	Belongs to the UPF0758 family
PBT91_09870	COG0401	homolog of Blt101
PBT91_09920	COG2204	response regulator
PBT91_09925	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
PBT91_09930	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
PBT91_09935	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
PBT91_09955	COG2205	protein histidine kinase activity
PBT91_09960	COG5002	protein histidine kinase activity
PBT91_09965	COG1477	protein flavinylation
PBT91_09985	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
PBT91_09990	COG0569	domain protein
PBT91_10015	COG1674	ftsk spoiiie
PBT91_10030	COG4974	Belongs to the 'phage' integrase family
PBT91_10035	COG0517	IMP dehydrogenase activity
PBT91_10080	COG4771	TonB-dependent receptor
PBT91_10115	COG0156	8-amino-7-oxononanoate synthase activity
PBT91_10215	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_10230	COG4977	sequence-specific DNA binding
PBT91_10230	COG1917	Cupin 2, conserved barrel domain protein
PBT91_10235	COG1733	regulation of RNA biosynthetic process
PBT91_10240	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_10250	COG4221	oxidoreductase activity
PBT91_10290	COG1846	Transcriptional regulator
PBT91_10300	COG0583	DNA-binding transcription factor activity
PBT91_10305	COG1280	lysine exporter protein (LysE YggA)
PBT91_10315	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
PBT91_10325	COG1054	Belongs to the UPF0176 family
PBT91_10340	COG2814	Major facilitator Superfamily
PBT91_10350	COG0667	Aldo Keto reductase
PBT91_10360	COG0300	oxidoreductase activity
PBT91_10365	COG2378	regulation of single-species biofilm formation
PBT91_10375	COG0517	IMP dehydrogenase activity
PBT91_10380	COG4974	Belongs to the 'phage' integrase family
PBT91_10395	COG3547	Transposase (IS116 IS110 IS902 family)
PBT91_10415	COG4771	TonB-dependent receptor
PBT91_10435	COG1278	Cold shock
PBT91_10440	COG2706	6-phosphogluconolactonase activity
PBT91_10445	COG0598	Magnesium transport protein CorA
PBT91_10475	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
PBT91_10485	COG1741	Belongs to the pirin family
PBT91_10505	COG1629	transport
PBT91_10505	COG4206	TonB-dependent receptor
PBT91_10525	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
PBT91_10525	COG0140	phosphoribosyl-ATP diphosphatase activity
PBT91_10530	COG0107	imidazoleglycerol-phosphate synthase activity
PBT91_10535	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
PBT91_10545	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
PBT91_10550	COG0131	Imidazoleglycerol-phosphate dehydratase
PBT91_10555	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
PBT91_10565	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
PBT91_10570	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
PBT91_10585	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_10590	COG0612	Peptidase, M16
PBT91_10620	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT91_10625	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
PBT91_10630	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT91_10635	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
PBT91_10635	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
PBT91_10640	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT91_10645	COG1078	dGTPase activity
PBT91_10650	COG2204	response regulator
PBT91_10655	COG0802	atpase or kinase
PBT91_10665	COG0686	Belongs to the AlaDH PNT family
PBT91_10675	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
PBT91_10680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
PBT91_10685	COG0655	NAD(P)H dehydrogenase (quinone) activity
PBT91_10700	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
PBT91_10735	COG0156	8-amino-7-oxononanoate synthase activity
PBT91_10750	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
PBT91_10770	COG2308	Evidence 4 Homologs of previously reported genes of
PBT91_10785	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PBT91_10790	COG1393	Belongs to the ArsC family
PBT91_10815	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
PBT91_10815	COG1333	cytochrome c biogenesis protein
PBT91_10835	COG0424	maF-like protein
PBT91_10850	COG0668	transmembrane transport
PBT91_10885	COG0415	Belongs to the DNA photolyase family
PBT91_10890	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
PBT91_10925	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
PBT91_10940	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
PBT91_10950	COG0259	pyridoxamine-phosphate oxidase activity
PBT91_10955	COG1234	tRNA 3'-trailer cleavage
PBT91_10965	COG0540	Belongs to the ATCase OTCase family
PBT91_10970	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
PBT91_10980	COG3781	membrane
PBT91_10985	COG0590	tRNA wobble adenosine to inosine editing
PBT91_10990	COG1082	Xylose isomerase domain protein TIM barrel
PBT91_10995	COG1846	Transcriptional regulator
PBT91_11000	COG1764	response to oxidative stress
PBT91_11015	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
PBT91_11020	COG4303	Ethanolamine ammonia lyase large subunit
PBT91_11025	COG4302	ethanolamine ammonia-lyase activity
PBT91_11065	COG2814	Major facilitator Superfamily
PBT91_11070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
PBT91_11080	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
PBT91_11085	COG1595	DNA-templated transcription, initiation
PBT91_11105	COG2270	Major facilitator Superfamily
PBT91_11125	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
PBT91_11135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBT91_11150	COG3279	Response regulator of the LytR AlgR family
PBT91_11160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
PBT91_11175	COG4974	Belongs to the 'phage' integrase family
PBT91_11180	COG0656	L-ascorbic acid biosynthetic process
PBT91_11185	COG1418	mRNA catabolic process
PBT91_11210	COG1104	cysteine desulfurase activity
PBT91_11245	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBT91_11250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
PBT91_11265	COG0116	Belongs to the methyltransferase superfamily
PBT91_11315	COG1363	Peptidase, m42
PBT91_11335	COG2176	DNA-directed DNA polymerase activity
PBT91_11340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
PBT91_11345	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
PBT91_11350	COG1702	phosphate starvation-inducible protein PhoH
PBT91_11375	COG0592	DNA-directed DNA polymerase activity
PBT91_11385	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
PBT91_11455	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
PBT91_11460	COG4680	protein conserved in bacteria
PBT91_11475	COG0604	alcohol dehydrogenase
PBT91_11475	COG3321	synthase
PBT91_11495	COG2133	pyrroloquinoline quinone binding
PBT91_11505	COG0572	uridine kinase
PBT91_11515	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT91_11520	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT91_11520	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
PBT91_11535	COG2201	protein-glutamate methylesterase activity
PBT91_11540	COG3275	phosphorelay sensor kinase activity
PBT91_11545	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_11550	COG1192	Involved in chromosome partitioning
PBT91_11555	COG1475	DNA binding
PBT91_11565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
PBT91_11570	COG0681	Belongs to the peptidase S26 family
PBT91_11595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
PBT91_11605	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
PBT91_11615	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
PBT91_11630	COG0105	UTP biosynthetic process
PBT91_11635	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
PBT91_11645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
PBT91_11650	COG2195	Cleaves the N-terminal amino acid of tripeptides
PBT91_11660	COG1228	amidohydrolase
PBT91_11670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
PBT91_11675	COG0501	Belongs to the peptidase M48B family
PBT91_11690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
PBT91_11710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
PBT91_11730	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
PBT91_11740	COG3956	TIGRFAM MazG family protein
PBT91_11765	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
PBT91_11770	COG0626	cystathionine gamma-synthase activity
PBT91_11775	COG0028	Belongs to the TPP enzyme family
PBT91_11780	COG1064	alcohol dehydrogenase
PBT91_11795	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_11815	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PBT91_11825	COG0045	succinate-CoA ligase (ADP-forming) activity
PBT91_11830	COG2814	Major facilitator Superfamily
PBT91_11835	COG0019	diaminopimelate decarboxylase activity
PBT91_11845	COG0516	GMP reductase activity
PBT91_11850	COG0494	nUDIX hydrolase
PBT91_11905	COG3530	Putative quorum-sensing-regulated virulence factor
PBT91_11910	COG0504	CTP synthase activity
PBT91_11915	COG0706	membrane insertase activity
PBT91_11930	COG0482	sulfurtransferase activity
PBT91_11960	COG0519	Catalyzes the synthesis of GMP from XMP
PBT91_11960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
PBT91_11975	COG0076	glutamate decarboxylase activity
PBT91_11980	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
PBT91_11990	COG0612	Peptidase, M16
PBT91_12000	COG1785	Belongs to the alkaline phosphatase family
PBT91_12005	COG0702	epimerase
PBT91_12010	COG4771	TonB-dependent receptor
PBT91_12015	COG2207	Transcriptional regulator
PBT91_12020	COG3250	beta-galactosidase activity
PBT91_12025	COG0702	epimerase
PBT91_12035	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
PBT91_12070	COG1304	FMN binding
PBT91_12080	COG4952	isomerase
PBT91_12085	COG3347	Dehydrogenase
PBT91_12085	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_12095	COG0738	Major facilitator superfamily
PBT91_12100	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_12110	COG3254	rhamnose metabolic process
PBT91_12115	COG1063	alcohol dehydrogenase
PBT91_12120	COG3250	beta-galactosidase activity
PBT91_12125	COG3250	beta-galactosidase activity
PBT91_12135	COG3408	Glycogen debranching enzyme
PBT91_12155	COG3408	Glycogen debranching enzyme
PBT91_12200	COG0702	epimerase
PBT91_12205	COG1629	transport
PBT91_12205	COG4206	TonB-dependent receptor
PBT91_12250	COG3940	Belongs to the glycosyl hydrolase 43 family
PBT91_12255	COG3250	beta-galactosidase activity
PBT91_12275	COG0673	inositol 2-dehydrogenase activity
PBT91_12310	COG3119	arylsulfatase activity
PBT91_12310	COG3408	Glycogen debranching enzyme
PBT91_12320	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT91_12335	COG3250	beta-galactosidase activity
PBT91_12340	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
PBT91_12345	COG4206	TonB-dependent receptor
PBT91_12345	COG1629	transport
PBT91_12350	COG0702	epimerase
PBT91_12355	COG1629	transport
PBT91_12370	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT91_12375	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBT91_12380	COG0179	Fumarylacetoacetate (FAA) hydrolase
PBT91_12415	COG2755	lipolytic protein G-D-S-L family
PBT91_12435	COG2755	lipolytic protein G-D-S-L family
PBT91_12445	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
PBT91_12460	COG4771	TonB-dependent receptor
PBT91_12480	COG0702	epimerase
PBT91_12485	COG1629	transport
PBT91_12490	COG1609	Transcriptional regulator
PBT91_12495	COG2721	sulfolactate sulfo-lyase activity
PBT91_12500	COG0246	Mannitol dehydrogenase
PBT91_12510	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
PBT91_12520	COG0800	Aldolase
PBT91_12530	COG1904	glucuronate isomerase
PBT91_12535	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_12540	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
PBT91_12545	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_12550	COG1312	Catalyzes the dehydration of D-mannonate
PBT91_12560	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PBT91_12565	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
PBT91_12575	COG2115	Belongs to the xylose isomerase family
PBT91_12585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
PBT91_12585	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
PBT91_12610	COG0477	Major facilitator Superfamily
PBT91_12610	COG2814	Major facilitator Superfamily
PBT91_12615	COG0671	phosphoesterase, PA-phosphatase related
PBT91_12625	COG0534	Mate efflux family protein
PBT91_12640	COG0071	Belongs to the small heat shock protein (HSP20) family
PBT91_12650	COG4585	Histidine kinase
PBT91_12655	COG2197	response regulator
PBT91_12660	COG0488	(ABC) transporter
PBT91_12675	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
PBT91_12700	COG1266	CAAX protease self-immunity
PBT91_12705	COG4948	Mandelate Racemase Muconate Lactonizing
PBT91_12710	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
PBT91_12715	COG1575	Belongs to the MenA family. Type 1 subfamily
PBT91_12730	COG0463	Glycosyl transferase, family 2
PBT91_12735	COG1360	Flagellar Motor Protein
PBT91_12740	COG0009	L-threonylcarbamoyladenylate synthase
PBT91_12755	COG1473	amidohydrolase
PBT91_12780	COG0308	aminopeptidase N
PBT91_12785	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
PBT91_12800	COG3852	Histidine kinase
PBT91_12835	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
PBT91_12840	COG1506	peptidase
PBT91_12855	COG0326	Molecular chaperone. Has ATPase activity
PBT91_12860	COG2198	Histidine kinase
PBT91_12860	COG5002	protein histidine kinase activity
PBT91_12860	COG0784	Response regulator, receiver
PBT91_12900	COG0561	phosphatase activity
PBT91_12915	COG0579	oxidoreductase
PBT91_12940	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
PBT91_12945	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
PBT91_12950	COG1115	amino acid carrier protein
PBT91_12955	COG0248	Ppx GppA phosphatase
PBT91_12965	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
PBT91_12970	COG0085	RNA polymerase activity
PBT91_12975	COG0222	ribosome binding
PBT91_12980	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
PBT91_12985	COG0081	regulation of translation
PBT91_12990	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
PBT91_13010	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
PBT91_13035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
PBT91_13040	COG4974	Belongs to the 'phage' integrase family
PBT91_13045	COG0828	Belongs to the bacterial ribosomal protein bS21 family
PBT91_13050	COG1960	acyl-CoA dehydrogenase activity
PBT91_13060	COG1115	amino acid carrier protein
PBT91_13080	COG1115	amino acid carrier protein
PBT91_13095	COG0577	efflux transmembrane transporter activity
PBT91_13100	COG3876	Protein conserved in bacteria
PBT91_13125	COG0514	ATP-dependent DNA helicase (RecQ)
PBT91_13130	COG0517	IMP dehydrogenase activity
PBT91_13130	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PBT91_13135	COG0805	protein transport
PBT91_13145	COG1137	ATPase activity
PBT91_13155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
PBT91_13160	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
PBT91_13165	COG0438	transferase activity, transferring glycosyl groups
PBT91_13200	COG0297	glycogen (starch) synthase activity
PBT91_13200	COG0438	transferase activity, transferring glycosyl groups
PBT91_13210	COG2089	acid synthase
PBT91_13215	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
PBT91_13255	COG0463	Glycosyl transferase, family 2
PBT91_13265	COG0463	Glycosyl transferase, family 2
PBT91_13265	COG1216	Glycosyl transferase, family 2
PBT91_13295	COG2226	methyltransferase
PBT91_13300	COG0489	protein tyrosine kinase activity
PBT91_13310	COG0488	(ABC) transporter
PBT91_13320	COG1136	(ABC) transporter
PBT91_13340	COG0653	protein targeting
PBT91_13375	COG1764	response to oxidative stress
PBT91_13380	COG1703	isobutyryl-CoA mutase activity
PBT91_13385	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT91_13390	COG0463	Glycosyl transferase, family 2
PBT91_13395	COG3952	Lipid A Biosynthesis
PBT91_13395	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
PBT91_13415	COG1595	DNA-templated transcription, initiation
PBT91_13435	COG1917	Cupin 2, conserved barrel domain protein
PBT91_13435	COG2169	Transcriptional regulator
PBT91_13440	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
PBT91_13450	COG3781	membrane
PBT91_13455	COG2205	protein histidine kinase activity
PBT91_13455	COG3437	response regulator, receiver
PBT91_13455	COG4999	Histidine kinase
PBT91_13455	COG3850	Histidine kinase
PBT91_13460	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBT91_13470	COG0584	glycerophosphoryl diester phosphodiesterase
PBT91_13485	COG2318	DinB family
PBT91_13525	COG0745	RESPONSE REGULATOR receiver
PBT91_13535	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
PBT91_13545	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT91_13550	COG1082	Xylose isomerase domain protein TIM barrel
PBT91_13555	COG1501	Belongs to the glycosyl hydrolase 31 family
PBT91_13560	COG3250	beta-galactosidase activity
PBT91_13570	COG0702	epimerase
PBT91_13575	COG4771	TonB-dependent receptor
PBT91_13580	COG2205	protein histidine kinase activity
PBT91_13580	COG3292	Two component regulator propeller
PBT91_13580	COG0745	RESPONSE REGULATOR receiver
PBT91_13590	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT91_13600	COG2942	2-epimerase
PBT91_13605	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
PBT91_13620	COG2207	Transcriptional regulator
PBT91_13630	COG3345	alpha-galactosidase
PBT91_13640	COG0702	epimerase
PBT91_13645	COG0561	phosphatase activity
PBT91_13650	COG4771	TonB-dependent receptor
PBT91_13680	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
PBT91_13690	COG1250	3-hydroxyacyl-CoA dehydrogenase
PBT91_13700	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
PBT91_13715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PBT91_13720	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
PBT91_13735	COG0237	dephospho-CoA kinase activity
PBT91_13750	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
PBT91_13755	COG0497	DNA recombination
PBT91_13780	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
PBT91_13785	COG0737	Belongs to the 5'-nucleotidase family
PBT91_13790	COG0737	Belongs to the 5'-nucleotidase family
PBT91_13795	COG0778	Nitroreductase
PBT91_13800	COG3119	arylsulfatase activity
PBT91_13805	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT91_13825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT91_13830	COG3119	arylsulfatase activity
PBT91_13860	COG1610	YqeY-like protein
PBT91_13870	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT91_13885	COG0702	epimerase
PBT91_13890	COG4771	TonB-dependent receptor
PBT91_13925	COG0820	rRNA (adenine-C2-)-methyltransferase activity
PBT91_13930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
PBT91_13960	COG1490	D-aminoacyl-tRNA deacylase activity
PBT91_13965	COG1162	GTPase activity
PBT91_13975	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
PBT91_13980	COG0287	Prephenate dehydrogenase
PBT91_13985	COG0436	Aminotransferase
PBT91_13990	COG0077	Prephenate dehydratase
PBT91_13990	COG1605	Chorismate mutase
PBT91_13995	COG1131	(ABC) transporter
PBT91_14000	COG0460	homoserine dehydrogenase
PBT91_14000	COG0527	aspartate kinase activity
PBT91_14005	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
PBT91_14015	COG0646	methionine synthase
PBT91_14015	COG1410	methionine synthase
PBT91_14020	COG1765	OsmC-like protein
PBT91_14025	COG0492	ferredoxin-NADP+ reductase activity
PBT91_14030	COG1648	precorrin-2 dehydrogenase activity
PBT91_14030	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
PBT91_14040	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBT91_14050	COG1959	2 iron, 2 sulfur cluster binding
PBT91_14070	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
PBT91_14080	COG1960	acyl-CoA dehydrogenase activity
PBT91_14085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
PBT91_14090	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
PBT91_14105	COG3273	potassium ion transport
PBT91_14105	COG0471	metal ion transport
PBT91_14120	COG1428	Deoxynucleoside kinase
PBT91_14130	COG0612	Peptidase, M16
PBT91_14135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
PBT91_14140	COG0702	epimerase
PBT91_14145	COG4771	TonB-dependent receptor
PBT91_14160	COG1595	DNA-templated transcription, initiation
PBT91_14175	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
PBT91_14180	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
PBT91_14190	COG0022	dehydrogenase e1 component
PBT91_14190	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT91_14200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
PBT91_14210	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
PBT91_14225	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
PBT91_14240	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT91_14290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
PBT91_14300	COG1519	Transferase
PBT91_14300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
PBT91_14360	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
PBT91_14375	COG0506	proline dehydrogenase activity
PBT91_14385	COG2249	NAD(P)H dehydrogenase (quinone) activity
PBT91_14550	COG3392	D12 class N6 adenine-specific DNA methyltransferase
PBT91_14615	COG3179	chitinase
PBT91_14680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PBT91_14685	COG1119	ATPase activity
PBT91_14690	COG2755	lipolytic protein G-D-S-L family
PBT91_14690	COG0657	acetylesterase activity
PBT91_14700	COG0823	Involved in the tonB-independent uptake of proteins
PBT91_14710	COG1428	Deoxynucleoside kinase
PBT91_14730	COG0110	maltose O-acetyltransferase activity
PBT91_14750	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
PBT91_14760	COG2515	1-aminocyclopropane-1-carboxylate deaminase
PBT91_14780	COG3186	Phenylalanine-4-hydroxylase
PBT91_14795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
PBT91_14800	COG0739	heme binding
PBT91_14830	COG1160	GTP binding
PBT91_14840	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
PBT91_14845	COG0659	secondary active sulfate transmembrane transporter activity
PBT91_14870	COG1846	Transcriptional regulator
PBT91_14875	COG0386	Belongs to the glutathione peroxidase family
PBT91_14885	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
PBT91_14890	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
PBT91_14895	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
PBT91_14900	COG1349	DNA-binding transcription factor activity
PBT91_14905	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
PBT91_14935	COG0798	PFAM Bile acid sodium symporter
PBT91_14955	COG0668	transmembrane transport
PBT91_14990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT91_14995	COG0488	(ABC) transporter
PBT91_15025	COG1262	PFAM Formylglycine-generating sulfatase enzyme
PBT91_15035	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
PBT91_15035	COG1754	DNA topoisomerase type I activity
PBT91_15040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
PBT91_15065	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
PBT91_15070	COG0459	protein refolding
PBT91_15080	COG3142	Participates in the control of copper homeostasis
PBT91_15105	COG0471	metal ion transport
PBT91_15130	COG1472	Belongs to the glycosyl hydrolase 3 family
PBT91_15145	COG1629	transport
PBT91_15155	COG3525	Glycosyl hydrolase, family 20, catalytic domain
PBT91_15160	COG3537	Alpha-1,2-mannosidase
PBT91_15175	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
PBT91_15185	COG3537	Alpha-1,2-mannosidase
PBT91_15195	COG3279	Response regulator of the LytR AlgR family
PBT91_15220	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
PBT91_15235	COG0463	Glycosyl transferase, family 2
PBT91_15245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
PBT91_15255	COG0463	Glycosyl transferase, family 2
PBT91_15260	COG1215	transferase activity, transferring glycosyl groups
PBT91_15285	COG0010	Belongs to the arginase family
PBT91_15290	COG1166	arginine decarboxylase activity
PBT91_15295	COG1187	pseudouridine synthase activity
PBT91_15320	COG2081	HI0933 family
PBT91_15325	COG0584	glycerophosphoryl diester phosphodiesterase
PBT91_15330	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_15335	COG2323	membrane
PBT91_15340	COG2808	Putative FMN-binding domain
PBT91_15345	COG0861	Integral membrane protein TerC family
PBT91_15355	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
PBT91_15365	COG0666	response to abiotic stimulus
PBT91_15375	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
PBT91_15380	COG0739	heme binding
PBT91_15400	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PBT91_15405	COG2315	Protein conserved in bacteria
PBT91_15430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
PBT91_15440	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
PBT91_15445	COG0463	Glycosyl transferase, family 2
PBT91_15490	COG0784	Response regulator, receiver
PBT91_15490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
PBT91_15490	COG2198	Histidine kinase
PBT91_15490	COG2205	protein histidine kinase activity
PBT91_15500	COG1346	cytolysis
PBT91_15505	COG1380	Effector of murein hydrolase LrgA
PBT91_15515	COG2072	flavoprotein involved in K transport
PBT91_15545	COG1607	acyl-coa hydrolase
PBT91_15550	COG4221	oxidoreductase activity
PBT91_15585	COG1538	Outer membrane efflux protein
PBT91_15595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
PBT91_15610	COG1629	transport
PBT91_15620	COG3292	Two component regulator propeller
PBT91_15620	COG2205	protein histidine kinase activity
PBT91_15620	COG0745	RESPONSE REGULATOR receiver
PBT91_15625	COG1629	transport
PBT91_15625	COG4206	TonB-dependent receptor
PBT91_15630	COG0702	epimerase
PBT91_15645	COG3250	beta-galactosidase activity
PBT91_15655	COG1082	Xylose isomerase domain protein TIM barrel
PBT91_15660	COG0545	Peptidyl-prolyl cis-trans isomerase
PBT91_15665	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
PBT91_15670	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
PBT91_15695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
PBT91_15700	COG0745	RESPONSE REGULATOR receiver
PBT91_15705	COG5002	protein histidine kinase activity
PBT91_15730	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_15750	COG1994	Peptidase M50
PBT91_15770	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
PBT91_15775	COG1335	isochorismatase
PBT91_15790	COG4974	Belongs to the 'phage' integrase family
PBT91_15810	COG1629	transport
PBT91_15820	COG1595	DNA-templated transcription, initiation
PBT91_15835	COG3118	belongs to the thioredoxin family
PBT91_15850	COG0228	four-way junction DNA binding
PBT91_15855	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
PBT91_15865	COG0495	leucyl-tRNA aminoacylation
PBT91_15875	COG2177	Part of the ABC transporter FtsEX involved in
PBT91_15885	COG1968	undecaprenyl-diphosphatase activity
PBT91_15890	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
PBT91_15905	COG0519	Catalyzes the synthesis of GMP from XMP
PBT91_15910	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
PBT91_15920	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
PBT91_15925	COG5002	protein histidine kinase activity
PBT91_15940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
PBT91_15970	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
PBT91_15985	COG1733	regulation of RNA biosynthetic process
PBT91_15990	COG0702	epimerase
PBT91_15995	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
PBT91_16005	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
PBT91_16030	COG1629	transport
PBT91_16040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
PBT91_16045	COG0261	This protein binds to 23S rRNA in the presence of protein L20
PBT91_16055	COG0612	Peptidase, M16
PBT91_16060	COG0612	Peptidase, M16
PBT91_16080	COG0629	single-stranded DNA binding
PBT91_16090	COG0776	regulation of translation
PBT91_16095	COG1530	ribonuclease E activity
PBT91_16105	COG2137	regulation of response to DNA damage stimulus
PBT91_16125	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
PBT91_16130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
PBT91_16135	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
PBT91_16140	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
PBT91_16145	COG0156	8-amino-7-oxononanoate synthase activity
PBT91_16150	COG1320	monovalent cation:proton antiporter activity
PBT91_16155	COG2212	antiporter activity
PBT91_16160	COG1863	multisubunit Na H antiporter MnhE subunit
PBT91_16165	COG0651	ATP synthesis coupled electron transport
PBT91_16170	COG1006	Multisubunit Na H antiporter MnhC subunit
PBT91_16175	COG2111	Na H antiporter
PBT91_16180	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
PBT91_16180	COG2111	Na H antiporter
PBT91_16190	COG3655	Transcriptional regulator
PBT91_16200	COG0355	proton-transporting ATP synthase activity, rotational mechanism
PBT91_16205	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
PBT91_16210	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
PBT91_16220	COG0297	glycogen (starch) synthase activity
PBT91_16225	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
PBT91_16230	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
PBT91_16245	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
PBT91_16255	COG0667	Aldo Keto reductase
PBT91_16260	COG1360	Flagellar Motor Protein
PBT91_16265	COG0708	Exodeoxyribonuclease III
PBT91_16275	COG2738	Putative neutral zinc metallopeptidase
PBT91_16280	COG0528	UMP kinase activity
PBT91_16285	COG0233	cytoplasmic translational termination
PBT91_16300	COG0017	Asparaginyl-tRNA synthetase
PBT91_16305	COG0564	pseudouridine synthase activity
PBT91_16310	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
PBT91_16330	COG0848	biopolymer transport protein
PBT91_16340	COG0811	peptide transport
PBT91_16350	COG0252	asparaginase activity
PBT91_16360	COG0084	hydrolase, TatD family'
PBT91_16370	COG0508	dehydrogenase complex catalyzes the overall conversion of
PBT91_16375	COG0567	Dehydrogenase, E1 component
PBT91_16385	COG1309	transcriptional regulator
PBT91_16410	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
PBT91_16440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
PBT91_16455	COG3590	peptidase
PBT91_16465	COG0792	nuclease activity
PBT91_16475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBT91_16475	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
PBT91_16480	COG0123	including yeast histone deacetylase and acetoin utilization protein
PBT91_16495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
PBT91_16500	COG0629	single-stranded DNA binding
PBT91_16515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
PBT91_16550	COG4109	DRTGG domain
PBT91_16575	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
PBT91_16580	COG2259	Doxx family
PBT91_16585	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_16590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
PBT91_16615	COG1061	Type III restriction enzyme res subunit
PBT91_16625	COG1053	succinate dehydrogenase
PBT91_16635	COG0367	asparagine synthase
PBT91_16640	COG1028	Short-chain dehydrogenase reductase Sdr
PBT91_16645	COG0006	proline dipeptidase activity
PBT91_16660	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
PBT91_16675	COG0719	Fe-S assembly protein
PBT91_16685	COG0396	ATPase activity
PBT91_16690	COG0719	Fe-S assembly protein
PBT91_16705	COG2166	iron-sulfur cluster assembly
PBT91_16710	COG2151	metal-sulfur cluster biosynthetic enzyme
PBT91_16725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
PBT91_16775	COG4771	TonB-dependent receptor
PBT91_16780	COG4771	TonB-dependent receptor
PBT91_16785	COG0166	Belongs to the GPI family
PBT91_16795	COG3483	tryptophan 2,3-dioxygenase activity
PBT91_16805	COG3185	4-Hydroxyphenylpyruvate dioxygenase
PBT91_16810	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
PBT91_16815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
PBT91_16830	COG0322	excinuclease ABC activity
PBT91_16840	COG0189	ligase activity
PBT91_16850	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
PBT91_16855	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
PBT91_16870	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
PBT91_16880	COG4206	TonB-dependent receptor
PBT91_16885	COG1381	Involved in DNA repair and RecF pathway recombination
PBT91_16890	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
PBT91_16905	COG1335	isochorismatase
PBT91_16910	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
PBT91_16935	COG1621	beta-fructofuranosidase activity
PBT91_16940	COG0024	Methionine aminopeptidase
PBT91_16945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
PBT91_16950	COG0750	zinc metalloprotease
PBT91_16955	COG1999	signal sequence binding
PBT91_16985	COG1321	iron dependent repressor
PBT91_16985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
PBT91_16990	COG4771	TonB-dependent receptor
PBT91_17005	COG0484	heat shock protein binding
PBT91_17020	COG1418	mRNA catabolic process
PBT91_17030	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
PBT91_17040	COG2312	Erythromycin esterase
PBT91_17050	COG1024	Enoyl-CoA hydratase
PBT91_17060	COG1981	membrane
PBT91_17075	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
PBT91_17090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
PBT91_17095	COG0181	hydroxymethylbilane synthase activity
PBT91_17105	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
PBT91_17120	COG0408	coproporphyrinogen oxidase activity
PBT91_17125	COG0113	porphobilinogen synthase activity
PBT91_17140	COG1253	flavin adenine dinucleotide binding
PBT91_17155	COG0823	Involved in the tonB-independent uptake of proteins
PBT91_17155	COG1506	peptidase
PBT91_17180	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
PBT91_17185	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
PBT91_17195	COG1774	PSP1 C-terminal conserved region
PBT91_17200	COG1054	Belongs to the UPF0176 family
PBT91_17210	COG0826	peptidase U32
PBT91_17215	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
PBT91_17240	COG0180	Tryptophanyl-tRNA synthetase
PBT91_17245	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
PBT91_17245	COG0758	DNA mediated transformation
PBT91_17255	COG1607	acyl-coa hydrolase
PBT91_17290	COG0756	dUTP diphosphatase activity
PBT91_17305	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
PBT91_17310	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
PBT91_17315	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PBT91_17320	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
PBT91_17325	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
PBT91_17330	COG0356	it plays a direct role in the translocation of protons across the membrane
PBT91_17375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
PBT91_17400	COG0151	Belongs to the GarS family
PBT91_17410	COG1215	transferase activity, transferring glycosyl groups
PBT91_17435	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
PBT91_17450	COG0126	phosphoglycerate kinase activity
PBT91_17455	COG0470	DNA polymerase III
PBT91_17480	COG0445	tRNA wobble uridine modification
PBT91_17485	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
PBT91_17495	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBT91_17515	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
PBT91_17520	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
PBT91_17540	COG0557	exoribonuclease II activity
PBT91_17545	COG0698	ribose 5-phosphate isomerase
PBT91_17550	COG2153	protein acetylation
PBT91_17555	COG0793	Belongs to the peptidase S41A family
PBT91_17560	COG0594	ribonuclease P activity
PBT91_17565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family