locus-tag	class	description
BZL39_A00150	COG3961	Belongs to the TPP enzyme family
BZL39_A00190	COG3961	Belongs to the TPP enzyme family
BZL39_A00240	COG0833	amino acid
BZL39_A00250	COG2040	homocysteine
BZL39_A00280	COG2271	Major facilitator Superfamily
BZL39_A00310	COG2814	Major facilitator Superfamily
BZL39_A00320	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BZL39_A00330	COG1063	alcohol dehydrogenase
BZL39_A00360	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_A00630	COG0644	oxidoreductase
BZL39_A00630	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BZL39_A00750	COG0833	amino acid
BZL39_A00760	COG0469	pyruvate kinase activity
BZL39_A00800	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BZL39_A00810	COG3266	domain, Protein
BZL39_A00810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BZL39_A00820	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BZL39_A00890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BZL39_A01090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_A01110	COG1643	Atp-dependent helicase
BZL39_A01270	COG1160	GTP binding
BZL39_A01280	COG0039	L-malate dehydrogenase activity
BZL39_A01290	COG0515	serine threonine protein kinase
BZL39_A01290	COG2815	serine threonine protein kinase
BZL39_A01310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BZL39_A01370	COG0513	Belongs to the DEAD box helicase family
BZL39_A01390	COG1252	NADH dehydrogenase
BZL39_A01420	COG0412	Dienelactone hydrolase
BZL39_A01570	COG4106	trans-aconitate 2-methyltransferase activity
BZL39_A01580	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BZL39_A01650	COG0617	tRNA 3'-terminal CCA addition
BZL39_A01700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_A01710	COG1129	ABC transporter
BZL39_A01890	COG0477	Major facilitator Superfamily
BZL39_A01890	COG2814	Major facilitator Superfamily
BZL39_A01900	COG0477	Major facilitator Superfamily
BZL39_A01900	COG2814	Major facilitator Superfamily
BZL39_A01940	COG0534	Mate efflux family protein
BZL39_A01950	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BZL39_A01960	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BZL39_A01980	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BZL39_A02020	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_A02040	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BZL39_A02050	COG0515	serine threonine protein kinase
BZL39_A02050	COG2815	serine threonine protein kinase
BZL39_A02120	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_A02130	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_A02150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BZL39_A02170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BZL39_A02220	COG4284	Utp--glucose-1-phosphate uridylyltransferase
BZL39_A02290	COG0003	Pfam Anion-transporting ATPase
BZL39_A02360	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
BZL39_A02520	COG0089	rRNA binding
BZL39_A02530	COG0670	Belongs to the BI1 family
BZL39_A02540	COG0039	L-malate dehydrogenase activity
BZL39_A02600	COG1914	H( )-stimulated, divalent metal cation uptake system
BZL39_A02720	COG0563	adenylate kinase activity
BZL39_A02820	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BZL39_A02840	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZL39_A02900	COG0200	Binds to the 23S rRNA
BZL39_A02970	COG0477	Major facilitator Superfamily
BZL39_A02970	COG2814	Major facilitator Superfamily
BZL39_A03090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZL39_A03090	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZL39_A03100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BZL39_A03120	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BZL39_A03140	COG0210	DNA helicase
BZL39_A03160	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZL39_A03160	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BZL39_A03190	COG0175	sulfate reduction
BZL39_A03200	COG0251	oxidation-reduction process
BZL39_A03210	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BZL39_A03260	COG0288	reversible hydration of carbon dioxide
BZL39_A03300	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_A03350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BZL39_A03430	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_A03500	COG0514	ATP-dependent DNA helicase (RecQ)
BZL39_A03510	COG2271	Major facilitator Superfamily
BZL39_A03520	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BZL39_A03520	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BZL39_A03540	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BZL39_A03620	COG0326	Molecular chaperone. Has ATPase activity
BZL39_A03670	COG0515	serine threonine protein kinase
BZL39_A03680	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BZL39_A03740	COG1131	(ABC) transporter
BZL39_A03740	COG1716	ATPase activity
BZL39_A03740	COG0842	Transport permease protein
BZL39_A03760	COG0736	holo-[acyl-carrier-protein] synthase activity
BZL39_A03800	COG0463	Glycosyl transferase, family 2
BZL39_A03830	COG1546	Belongs to the CinA family
BZL39_A03830	COG1058	Belongs to the CinA family
BZL39_A03900	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BZL39_A03910	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BZL39_A03950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BZL39_A04020	COG0352	thiamine-phosphate diphosphorylase activity
BZL39_A04100	COG0513	Belongs to the DEAD box helicase family
BZL39_A04130	COG0051	transcription antitermination factor activity, RNA binding
BZL39_A04140	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BZL39_A04160	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BZL39_A04180	COG0515	serine threonine protein kinase
BZL39_A04180	COG2815	serine threonine protein kinase
BZL39_A04230	COG1024	Enoyl-CoA hydratase
BZL39_A04260	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZL39_A04310	COG0534	Mate efflux family protein
BZL39_A04470	COG2119	membrane
BZL39_A04490	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_A04630	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZL39_A04870	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_A04950	COG0217	transcriptional regulatory protein
BZL39_A04980	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BZL39_A05000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZL39_A05120	COG0180	Tryptophanyl-tRNA synthetase
BZL39_A05350	COG0513	Belongs to the DEAD box helicase family
BZL39_A05640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZL39_A05710	COG0513	Belongs to the DEAD box helicase family
BZL39_A06010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BZL39_A06040	COG0564	pseudouridine synthase activity
BZL39_A06070	COG1218	3'(2'),5'-bisphosphate nucleotidase
BZL39_A06080	COG0482	sulfurtransferase activity
BZL39_A06090	COG0513	Belongs to the DEAD box helicase family
BZL39_A06120	COG0515	serine threonine protein kinase
BZL39_A06160	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZL39_A06180	COG1253	flavin adenine dinucleotide binding
BZL39_A06250	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BZL39_A06310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BZL39_A06330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZL39_A06350	COG0484	heat shock protein binding
BZL39_A06380	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BZL39_A06390	COG0081	regulation of translation
BZL39_A06440	COG0477	Major facilitator Superfamily
BZL39_A06460	COG1132	(ABC) transporter
BZL39_A06570	COG0328	RNA-DNA hybrid ribonuclease activity
BZL39_A06710	COG1657	PFAM Prenyltransferase squalene oxidase
BZL39_A06750	COG2815	serine threonine protein kinase
BZL39_A06750	COG0515	serine threonine protein kinase
BZL39_A06820	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_A07030	COG0203	ribosomal protein L17
BZL39_A07040	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BZL39_A07090	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BZL39_A07110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BZL39_A07210	COG0484	heat shock protein binding
BZL39_A07240	COG1196	nuclear chromosome segregation
BZL39_A07280	COG1185	polyribonucleotide nucleotidyltransferase activity
BZL39_A07380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_A07380	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_A07400	COG2814	Major facilitator Superfamily
BZL39_A07430	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BZL39_A07450	COG0386	Belongs to the glutathione peroxidase family
BZL39_A07460	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_A07480	COG1160	GTP binding
BZL39_A07500	COG2814	Major facilitator Superfamily
BZL39_A07510	COG0477	Major facilitator Superfamily
BZL39_A07550	COG0107	imidazoleglycerol-phosphate synthase activity
BZL39_A07560	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZL39_A07590	COG0724	RNA recognition motif
BZL39_A07660	COG0477	Major facilitator Superfamily
BZL39_A07700	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BZL39_A07700	COG0517	IMP dehydrogenase activity
BZL39_A07730	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BZL39_A07920	COG0525	valine-tRNA ligase activity
BZL39_A07950	COG0515	serine threonine protein kinase
BZL39_A08070	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BZL39_A08090	COG0515	serine threonine protein kinase
BZL39_A08140	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BZL39_A08170	COG1902	pentaerythritol trinitrate reductase activity
BZL39_A08180	COG1902	pentaerythritol trinitrate reductase activity
BZL39_A08220	COG0148	phosphopyruvate hydratase activity
BZL39_A08300	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BZL39_A08350	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BZL39_A08380	COG0363	glucosamine-6-phosphate deaminase activity
BZL39_A08430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BZL39_A08440	COG2217	Heavy metal translocating P-type atpase
BZL39_A08470	COG0180	Tryptophanyl-tRNA synthetase
BZL39_A08560	COG0612	Peptidase, M16
BZL39_A08660	COG0588	phosphoglycerate mutase activity
BZL39_A08670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BZL39_A08700	COG1053	succinate dehydrogenase
BZL39_A08770	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BZL39_A08920	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZL39_A09110	COG0484	heat shock protein binding
BZL39_A09150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BZL39_A09180	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BZL39_A09180	COG0473	3-isopropylmalate dehydrogenase activity
BZL39_A09320	COG3961	Belongs to the TPP enzyme family
BZL39_A09330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BZL39_A09380	COG0493	'glutamate synthase
BZL39_A09400	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_A09460	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BZL39_A09590	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BZL39_A09630	COG0557	exoribonuclease II activity
BZL39_A09640	COG0488	(ABC) transporter
BZL39_A09660	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BZL39_A09740	COG1252	NADH dehydrogenase
BZL39_A09800	COG0165	Argininosuccinate lyase
BZL39_A09810	COG0017	Asparaginyl-tRNA synthetase
BZL39_A09820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BZL39_A09890	COG2815	serine threonine protein kinase
BZL39_A09890	COG0515	serine threonine protein kinase
BZL39_A09930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BZL39_A09940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZL39_A10000	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_A10010	COG0626	cystathionine gamma-synthase activity
BZL39_A10050	COG0154	amidase activity
BZL39_A10090	COG2814	Major facilitator Superfamily
BZL39_A10120	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BZL39_A10120	COG4106	trans-aconitate 2-methyltransferase activity
BZL39_A10150	COG4106	trans-aconitate 2-methyltransferase activity
BZL39_B00140	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_B00150	COG0833	amino acid
BZL39_B00170	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BZL39_B00220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BZL39_B00260	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BZL39_B00280	COG3579	cysteine-type endopeptidase activity
BZL39_B00290	COG1404	Belongs to the peptidase S8 family
BZL39_B00390	COG0625	glutathione transferase activity
BZL39_B00400	COG0484	heat shock protein binding
BZL39_B00480	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BZL39_B00510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZL39_B00530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BZL39_B00760	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BZL39_B00760	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BZL39_B00960	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BZL39_B01020	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BZL39_B01070	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BZL39_B01190	COG0277	FAD linked oxidase domain protein
BZL39_B01200	COG0656	L-ascorbic acid biosynthetic process
BZL39_B01250	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BZL39_B01290	COG0167	dihydroorotate dehydrogenase activity
BZL39_B01320	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BZL39_B01370	COG0006	proline dipeptidase activity
BZL39_B01440	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_B01490	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZL39_B01490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BZL39_B01540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BZL39_B01580	COG2224	Isocitrate lyase
BZL39_B01620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZL39_B01630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZL39_B01670	COG0251	oxidation-reduction process
BZL39_B01710	COG0659	secondary active sulfate transmembrane transporter activity
BZL39_B01720	COG0114	fumarate hydratase activity
BZL39_B01820	COG1741	Belongs to the pirin family
BZL39_B02200	COG1335	isochorismatase
BZL39_B02230	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_B02230	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_B02250	COG0113	porphobilinogen synthase activity
BZL39_B02290	COG0724	RNA recognition motif
BZL39_B02340	COG0724	RNA recognition motif
BZL39_B02500	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BZL39_B02520	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BZL39_B02550	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BZL39_B02620	COG0667	Aldo Keto reductase
BZL39_B02640	COG3265	gluconokinase activity
BZL39_B02700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_B02700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_B02970	COG0473	3-isopropylmalate dehydrogenase activity
BZL39_B02980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BZL39_B02980	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BZL39_B03000	COG0515	serine threonine protein kinase
BZL39_B03000	COG2815	serine threonine protein kinase
BZL39_B03020	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BZL39_B03070	COG0473	3-isopropylmalate dehydrogenase activity
BZL39_B03200	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BZL39_B03340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BZL39_B03470	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BZL39_B03480	COG2040	homocysteine
BZL39_B03600	COG1252	NADH dehydrogenase
BZL39_B03640	COG0484	heat shock protein binding
BZL39_B03690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BZL39_B03700	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BZL39_B03770	COG0459	protein refolding
BZL39_B03820	COG0187	DNA topoisomerase II activity
BZL39_B04130	COG0484	heat shock protein binding
BZL39_B04320	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_B04350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BZL39_B04360	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BZL39_B04420	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BZL39_B04500	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BZL39_B04520	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
BZL39_B04580	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BZL39_B04600	COG1113	amino acid transport
BZL39_B04860	COG0753	catalase activity
BZL39_B04890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZL39_B05160	COG1053	succinate dehydrogenase
BZL39_B05270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BZL39_B05280	COG2814	Major facilitator Superfamily
BZL39_B05320	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZL39_B05330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BZL39_B05330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BZL39_B05340	COG4285	Biotin-protein ligase, N terminal
BZL39_B05350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BZL39_B05360	COG0459	protein refolding
BZL39_B05450	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BZL39_B05550	COG1610	YqeY-like protein
BZL39_B05570	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BZL39_B05610	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BZL39_B05670	COG0822	iron-sulfur transferase activity
BZL39_B05720	COG0515	serine threonine protein kinase
BZL39_B05720	COG2815	serine threonine protein kinase
BZL39_B05730	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BZL39_B05740	COG0515	serine threonine protein kinase
BZL39_B05810	COG3842	ATPase activity
BZL39_B05880	COG2815	serine threonine protein kinase
BZL39_B05880	COG0515	serine threonine protein kinase
BZL39_B05890	COG0285	dihydrofolate synthase activity
BZL39_B05910	COG0585	pseudouridine synthase activity
BZL39_B06020	COG0495	leucyl-tRNA aminoacylation
BZL39_B06070	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BZL39_B06100	COG2897	thiosulfate sulfurtransferase activity
BZL39_B06130	COG0417	DNA replication proofreading
BZL39_B06210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZL39_B06230	COG4221	oxidoreductase activity
BZL39_B06250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BZL39_B06330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BZL39_B06350	COG0515	serine threonine protein kinase
BZL39_B06360	COG0724	RNA recognition motif
BZL39_B06420	COG0753	catalase activity
BZL39_B06460	COG1785	Belongs to the alkaline phosphatase family
BZL39_B06580	COG2815	serine threonine protein kinase
BZL39_B06580	COG0515	serine threonine protein kinase
BZL39_B06620	COG1131	(ABC) transporter
BZL39_B06620	COG1716	ATPase activity
BZL39_B06620	COG0842	Transport permease protein
BZL39_B06630	COG0842	Transport permease protein
BZL39_B06630	COG1131	(ABC) transporter
BZL39_B06630	COG1716	ATPase activity
BZL39_B06650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BZL39_B06820	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BZL39_B06870	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BZL39_B06910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BZL39_B07010	COG0626	cystathionine gamma-synthase activity
BZL39_B07020	COG1362	aminopeptidase activity
BZL39_B07040	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BZL39_B07120	COG0656	L-ascorbic acid biosynthetic process
BZL39_B07320	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZL39_B07390	COG0513	Belongs to the DEAD box helicase family
BZL39_B07470	COG1648	precorrin-2 dehydrogenase activity
BZL39_B07470	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BZL39_B07510	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BZL39_B07580	COG2815	serine threonine protein kinase
BZL39_B07580	COG0515	serine threonine protein kinase
BZL39_B07600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BZL39_B07620	COG0450	alkyl hydroperoxide reductase
BZL39_B07650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZL39_B07710	COG0443	Heat shock 70 kDa protein
BZL39_B07720	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BZL39_B07770	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BZL39_B07960	COG0024	Methionine aminopeptidase
BZL39_B07990	COG0367	asparagine synthase
BZL39_B08070	COG0004	ammonium transporteR
BZL39_B08200	COG0667	Aldo Keto reductase
BZL39_B08250	COG3346	SURF1 family
BZL39_B08350	COG0058	SHG alpha-glucan phosphorylase activity
BZL39_B08360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZL39_B08380	COG1183	phosphatidylcholine synthase activity
BZL39_B08630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BZL39_B08680	COG0588	phosphoglycerate mutase activity
BZL39_B08690	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BZL39_B08720	COG1053	succinate dehydrogenase
BZL39_B08780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BZL39_B08790	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BZL39_B08940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZL39_B09070	COG0484	heat shock protein binding
BZL39_B09110	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BZL39_B09280	COG3961	Belongs to the TPP enzyme family
BZL39_B09290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BZL39_B09340	COG0493	'glutamate synthase
BZL39_B09360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_B09420	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BZL39_B09550	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BZL39_B09590	COG0557	exoribonuclease II activity
BZL39_B09600	COG0488	(ABC) transporter
BZL39_B09620	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BZL39_B09700	COG1252	NADH dehydrogenase
BZL39_B09750	COG0165	Argininosuccinate lyase
BZL39_B09760	COG0017	Asparaginyl-tRNA synthetase
BZL39_B09770	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BZL39_B09840	COG2815	serine threonine protein kinase
BZL39_B09840	COG0515	serine threonine protein kinase
BZL39_B09880	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BZL39_B09890	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BZL39_B09960	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_B09970	COG0626	cystathionine gamma-synthase activity
BZL39_B10020	COG0154	amidase activity
BZL39_B10060	COG2814	Major facilitator Superfamily
BZL39_C00140	COG3961	Belongs to the TPP enzyme family
BZL39_C00150	COG0798	PFAM Bile acid sodium symporter
BZL39_C00230	COG0667	Aldo Keto reductase
BZL39_C00240	COG1064	alcohol dehydrogenase
BZL39_C00250	COG0667	Aldo Keto reductase
BZL39_C00270	COG0667	Aldo Keto reductase
BZL39_C00300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BZL39_C00440	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BZL39_C00490	COG0039	L-malate dehydrogenase activity
BZL39_C00610	COG1643	Atp-dependent helicase
BZL39_C00620	COG2814	Major facilitator Superfamily
BZL39_C00630	COG2814	Major facilitator Superfamily
BZL39_C00640	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BZL39_C00740	COG0443	Heat shock 70 kDa protein
BZL39_C00780	COG1956	GAF domain-containing protein
BZL39_C00820	COG2226	methyltransferase
BZL39_C00910	COG0443	Heat shock 70 kDa protein
BZL39_C01030	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZL39_C01130	COG0564	pseudouridine synthase activity
BZL39_C01190	COG0408	coproporphyrinogen oxidase activity
BZL39_C01290	COG2816	NAD+ diphosphatase activity
BZL39_C01310	COG0515	serine threonine protein kinase
BZL39_C01320	COG2815	serine threonine protein kinase
BZL39_C01320	COG0515	serine threonine protein kinase
BZL39_C01330	COG0222	ribosome binding
BZL39_C01420	COG0513	Belongs to the DEAD box helicase family
BZL39_C01590	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BZL39_C01640	COG0489	protein tyrosine kinase activity
BZL39_C01830	COG2815	serine threonine protein kinase
BZL39_C01830	COG0515	serine threonine protein kinase
BZL39_C01900	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BZL39_C01950	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BZL39_C01960	COG0205	6-phosphofructokinase activity
BZL39_C02040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BZL39_C02040	COG1017	nitric oxide dioxygenase activity
BZL39_C02210	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BZL39_C02220	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BZL39_C02280	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BZL39_C02330	COG0181	hydroxymethylbilane synthase activity
BZL39_C02340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BZL39_C02360	COG0156	8-amino-7-oxononanoate synthase activity
BZL39_C02410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BZL39_C02430	COG2814	Major facilitator Superfamily
BZL39_C02690	COG0459	protein refolding
BZL39_C02730	COG3844	kynureninase activity
BZL39_C02760	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BZL39_C02760	COG0551	DNA topoisomerase type I activity
BZL39_C02830	COG0321	lipoyl(octanoyl) transferase activity
BZL39_C02990	COG0024	Methionine aminopeptidase
BZL39_C03150	COG0612	Peptidase, M16
BZL39_C03200	COG2814	Major facilitator Superfamily
BZL39_C03220	COG0673	inositol 2-dehydrogenase activity
BZL39_C03350	COG0089	rRNA binding
BZL39_C03360	COG0670	Belongs to the BI1 family
BZL39_C03370	COG0039	L-malate dehydrogenase activity
BZL39_C03420	COG1914	H( )-stimulated, divalent metal cation uptake system
BZL39_C03560	COG0563	adenylate kinase activity
BZL39_C03690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZL39_C03750	COG0200	Binds to the 23S rRNA
BZL39_C03820	COG2814	Major facilitator Superfamily
BZL39_C03820	COG0477	Major facilitator Superfamily
BZL39_C03940	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZL39_C03940	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZL39_C03950	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BZL39_C03990	COG0210	DNA helicase
BZL39_C04010	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZL39_C04010	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BZL39_C04050	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BZL39_C04060	COG0656	L-ascorbic acid biosynthetic process
BZL39_C04150	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BZL39_C04200	COG0513	Belongs to the DEAD box helicase family
BZL39_C04500	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BZL39_C04530	COG0564	pseudouridine synthase activity
BZL39_C04560	COG1218	3'(2'),5'-bisphosphate nucleotidase
BZL39_C04570	COG0482	sulfurtransferase activity
BZL39_C04580	COG0513	Belongs to the DEAD box helicase family
BZL39_C04610	COG0515	serine threonine protein kinase
BZL39_C04650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZL39_C04670	COG1253	flavin adenine dinucleotide binding
BZL39_C04740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BZL39_C04800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BZL39_C04820	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BZL39_C04880	COG0133	tryptophan synthase activity
BZL39_C04910	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BZL39_C05000	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BZL39_C05010	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BZL39_C05040	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BZL39_C05130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BZL39_C05140	COG1064	alcohol dehydrogenase
BZL39_C05160	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BZL39_C05470	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BZL39_C05550	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BZL39_C05590	COG0662	Cupin 2, conserved barrel domain protein
BZL39_C05600	COG0235	Class ii aldolase
BZL39_C05640	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BZL39_C05650	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BZL39_C05710	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
BZL39_C05830	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZL39_C05840	COG2046	Belongs to the sulfate adenylyltransferase family
BZL39_C05840	COG0529	Catalyzes the synthesis of activated sulfate
BZL39_C06020	COG0142	geranyltranstransferase activity
BZL39_C06100	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BZL39_C06170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BZL39_C06190	COG0833	amino acid
BZL39_C06290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BZL39_C06350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZL39_C06390	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BZL39_C06400	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BZL39_C06480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BZL39_C06550	COG2815	serine threonine protein kinase
BZL39_C06550	COG0515	serine threonine protein kinase
BZL39_C06570	COG1069	ribulokinase activity
BZL39_C06680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BZL39_C06740	COG4106	trans-aconitate 2-methyltransferase activity
BZL39_C06760	COG1605	Chorismate mutase
BZL39_C06760	COG0077	Prephenate dehydratase
BZL39_C06800	COG0738	Major facilitator superfamily
BZL39_C06810	COG2814	Major facilitator Superfamily
BZL39_C06830	COG1073	alpha beta
BZL39_C06870	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BZL39_C06940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_C06950	COG0123	including yeast histone deacetylase and acetoin utilization protein
BZL39_C06960	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BZL39_C07040	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
BZL39_C07110	COG0003	Pfam Anion-transporting ATPase
BZL39_C07180	COG4284	Utp--glucose-1-phosphate uridylyltransferase
BZL39_C07230	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BZL39_C07250	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BZL39_C07270	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_C07280	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_C07360	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BZL39_C07380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_C07420	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BZL39_C07440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BZL39_C07450	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BZL39_C07460	COG0534	Mate efflux family protein
BZL39_C07500	COG0477	Major facilitator Superfamily
BZL39_C07500	COG2814	Major facilitator Superfamily
BZL39_C07520	COG0477	Major facilitator Superfamily
BZL39_C07520	COG2814	Major facilitator Superfamily
BZL39_C07670	COG0656	L-ascorbic acid biosynthetic process
BZL39_C07690	COG0492	ferredoxin-NADP+ reductase activity
BZL39_C07720	COG0484	heat shock protein binding
BZL39_C07750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BZL39_C07750	COG0519	Catalyzes the synthesis of GMP from XMP
BZL39_C07860	COG0588	phosphoglycerate mutase activity
BZL39_C07990	COG1196	nuclear chromosome segregation
BZL39_C08020	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BZL39_C08170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZL39_C08260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BZL39_C08280	COG0049	tRNA binding
BZL39_C08400	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BZL39_C08400	COG2857	Cytochrome c1
BZL39_C08410	COG0435	Glutathione S-transferase
BZL39_C08450	COG1234	tRNA 3'-trailer cleavage
BZL39_C08520	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BZL39_C08570	COG1643	Atp-dependent helicase
BZL39_C08610	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_C08690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_C08730	COG0167	dihydroorotate dehydrogenase activity
BZL39_C08740	COG2267	carboxylic ester hydrolase activity
BZL39_C08770	COG0833	amino acid
BZL39_C08800	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BZL39_D00270	COG0626	cystathionine gamma-synthase activity
BZL39_D00280	COG2119	membrane
BZL39_D00290	COG0626	cystathionine gamma-synthase activity
BZL39_D00320	COG0384	phenazine biosynthesis protein PhzF
BZL39_D00360	COG0563	adenylate kinase activity
BZL39_D00470	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BZL39_D00550	COG0463	Glycosyl transferase, family 2
BZL39_D00730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BZL39_D00740	COG0656	L-ascorbic acid biosynthetic process
BZL39_D00830	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BZL39_D00870	COG0443	Heat shock 70 kDa protein
BZL39_D00990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_D01010	COG0443	Heat shock 70 kDa protein
BZL39_D01150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZL39_D01190	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BZL39_D01200	COG0123	including yeast histone deacetylase and acetoin utilization protein
BZL39_D01230	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BZL39_D01240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZL39_D01280	COG0513	Belongs to the DEAD box helicase family
BZL39_D01480	COG0515	serine threonine protein kinase
BZL39_D01480	COG2815	serine threonine protein kinase
BZL39_D01500	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BZL39_D01550	COG1793	dna ligase
BZL39_D01560	COG5398	heme oxygenase
BZL39_D01620	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BZL39_D01710	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_D01870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BZL39_D01890	COG0626	cystathionine gamma-synthase activity
BZL39_D01920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BZL39_D01920	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BZL39_D02070	COG1132	(ABC) transporter
BZL39_D02080	COG2815	serine threonine protein kinase
BZL39_D02080	COG0515	serine threonine protein kinase
BZL39_D02100	COG0678	peroxiredoxin activity
BZL39_D02100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZL39_D02320	COG2815	serine threonine protein kinase
BZL39_D02320	COG0515	serine threonine protein kinase
BZL39_D02370	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
BZL39_D02460	COG5265	(ABC) transporter
BZL39_D02540	COG0156	8-amino-7-oxononanoate synthase activity
BZL39_D02570	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BZL39_D02590	COG0154	amidase activity
BZL39_D02600	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_D02630	COG0302	gtp cyclohydrolase
BZL39_D02640	COG1357	PFAM Pentapeptide repeats (8 copies)
BZL39_D02640	COG0515	serine threonine protein kinase
BZL39_D02670	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_D02670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_D02800	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BZL39_D02900	COG0204	Acyl-transferase
BZL39_D02990	COG0443	Heat shock 70 kDa protein
BZL39_D03040	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BZL39_D03100	COG0513	Belongs to the DEAD box helicase family
BZL39_D03200	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BZL39_D03210	COG3961	Belongs to the TPP enzyme family
BZL39_D03230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZL39_D03240	COG3830	Belongs to the UPF0237 family
BZL39_D03240	COG0560	Phosphoserine phosphatase
BZL39_D03255	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_D03255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_D03270	COG0688	phosphatidylethanolamine metabolic process
BZL39_D03300	COG0513	Belongs to the DEAD box helicase family
BZL39_D03330	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BZL39_D03420	COG0475	glutathione-regulated potassium exporter activity
BZL39_D03430	COG0210	DNA helicase
BZL39_D03480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BZL39_D03550	COG0513	Belongs to the DEAD box helicase family
BZL39_D03640	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BZL39_D03760	COG1612	heme a metabolic process
BZL39_D03820	COG0156	8-amino-7-oxononanoate synthase activity
BZL39_D03830	COG1119	ATPase activity
BZL39_D03920	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BZL39_D03980	COG0515	serine threonine protein kinase
BZL39_D04010	COG2873	o-acetylhomoserine
BZL39_D04020	COG1132	(ABC) transporter
BZL39_D04030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BZL39_D04110	COG0017	Asparaginyl-tRNA synthetase
BZL39_D04180	COG2217	Heavy metal translocating P-type atpase
BZL39_D04220	COG0443	Heat shock 70 kDa protein
BZL39_D04250	COG0542	response to heat
BZL39_D04270	COG0316	Belongs to the HesB IscA family
BZL39_D04280	COG2814	Major facilitator Superfamily
BZL39_D04290	COG2814	Major facilitator Superfamily
BZL39_D04410	COG0052	Belongs to the universal ribosomal protein uS2 family
BZL39_D04510	COG0529	Catalyzes the synthesis of activated sulfate
BZL39_D04620	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_D04680	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BZL39_D04720	COG0281	malic enzyme
BZL39_D04770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BZL39_D04860	COG2116	formate transmembrane transporter activity
BZL39_D04890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZL39_D05020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BZL39_D05040	COG2814	Major facilitator Superfamily
BZL39_D05070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BZL39_D05080	COG0473	3-isopropylmalate dehydrogenase activity
BZL39_D05130	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BZL39_D05210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_D05270	COG1957	nucleoside hydrolase
BZL39_D05280	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BZL39_D05280	COG2124	cytochrome p450
BZL39_D05310	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BZL39_D05320	COG0085	RNA polymerase activity
BZL39_D05350	COG0842	Transport permease protein
BZL39_D05350	COG1716	ATPase activity
BZL39_D05350	COG1131	(ABC) transporter
BZL39_D05360	COG1716	ATPase activity
BZL39_D05360	COG1131	(ABC) transporter
BZL39_D05360	COG0842	Transport permease protein
BZL39_D05370	COG1716	ATPase activity
BZL39_D05370	COG0842	Transport permease protein
BZL39_D05370	COG1131	(ABC) transporter
BZL39_D05440	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BZL39_D05450	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BZL39_D05530	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BZL39_D05550	COG1394	ATPase activity, coupled to movement of substances
BZL39_D05570	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BZL39_D05590	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BZL39_D05600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BZL39_D05760	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BZL39_D05870	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BZL39_D05940	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BZL39_D05960	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BZL39_D05990	COG0386	Belongs to the glutathione peroxidase family
BZL39_D06000	COG2814	Major facilitator Superfamily
BZL39_D06020	COG0277	FAD linked oxidase domain protein
BZL39_D06080	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BZL39_D06110	COG0450	alkyl hydroperoxide reductase
BZL39_D06140	COG0194	GDP metabolic process
BZL39_D06150	COG0025	NhaP-type Na H and K H
BZL39_D06290	COG2124	cytochrome p450
BZL39_D06320	COG0475	glutathione-regulated potassium exporter activity
BZL39_D06380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BZL39_D06430	COG0513	Belongs to the DEAD box helicase family
BZL39_D06440	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BZL39_D06470	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BZL39_D06550	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BZL39_D06570	COG0481	GTPase activity
BZL39_D06750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BZL39_D06780	COG0488	(ABC) transporter
BZL39_D06850	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BZL39_D06890	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BZL39_D06990	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BZL39_D07010	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BZL39_D07020	COG0445	tRNA wobble uridine modification
BZL39_D07070	COG0157	Belongs to the NadC ModD family
BZL39_D07090	COG0666	response to abiotic stimulus
BZL39_D07130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BZL39_D07180	COG5212	phosphodiesterase
BZL39_D07190	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BZL39_D07220	COG1111	helicase
BZL39_D07220	COG1205	dead DEAH box helicase
BZL39_E00160	COG0753	catalase activity
BZL39_E00310	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BZL39_E00390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BZL39_E00420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BZL39_E00460	COG0459	protein refolding
BZL39_E00540	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_E00560	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BZL39_E00690	COG0724	RNA recognition motif
BZL39_E00720	COG0688	phosphatidylethanolamine metabolic process
BZL39_E00740	COG0179	Fumarylacetoacetate (FAA) hydrolase
BZL39_E00810	COG0481	GTPase activity
BZL39_E00850	COG0515	serine threonine protein kinase
BZL39_E00880	COG0004	ammonium transporteR
BZL39_E00930	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BZL39_E01050	COG0175	sulfate reduction
BZL39_E01070	COG0537	adenosine 5'-monophosphoramidase activity
BZL39_E01080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_E01100	COG0109	protoheme IX farnesyltransferase activity
BZL39_E01160	COG3064	Membrane
BZL39_E01160	COG4991	sh3 domain protein
BZL39_E01160	COG0515	serine threonine protein kinase
BZL39_E01210	COG0505	Belongs to the CarA family
BZL39_E01360	COG1230	cation diffusion facilitator family transporter
BZL39_E01450	COG0076	glutamate decarboxylase activity
BZL39_E01460	COG0667	Aldo Keto reductase
BZL39_E01490	COG0724	RNA recognition motif
BZL39_E01600	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BZL39_E01640	COG0022	dehydrogenase e1 component
BZL39_E01640	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZL39_E01650	COG0318	PFAM AMP-dependent synthetase and ligase
BZL39_E01670	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BZL39_E01690	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BZL39_E01750	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BZL39_E01780	COG1643	Atp-dependent helicase
BZL39_E01940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZL39_E02040	COG2351	hydroxyisourate hydrolase activity
BZL39_E02170	COG1129	ABC transporter
BZL39_E02180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_E02230	COG0617	tRNA 3'-terminal CCA addition
BZL39_E02300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BZL39_E02460	COG0412	Dienelactone hydrolase
BZL39_E02490	COG1252	NADH dehydrogenase
BZL39_E02510	COG0513	Belongs to the DEAD box helicase family
BZL39_E02570	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BZL39_E02590	COG2815	serine threonine protein kinase
BZL39_E02590	COG0515	serine threonine protein kinase
BZL39_E02600	COG0039	L-malate dehydrogenase activity
BZL39_E02610	COG1160	GTP binding
BZL39_E02760	COG1643	Atp-dependent helicase
BZL39_E02780	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_E02970	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BZL39_E02980	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BZL39_E03130	COG0443	Heat shock 70 kDa protein
BZL39_E03150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_E03200	COG0459	protein refolding
BZL39_E03270	COG0443	Heat shock 70 kDa protein
BZL39_E03330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BZL39_E03620	COG0513	Belongs to the DEAD box helicase family
BZL39_E03780	COG0180	Tryptophanyl-tRNA synthetase
BZL39_E03900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZL39_E03920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BZL39_E04030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_E04270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BZL39_E04410	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_E04430	COG2119	membrane
BZL39_E04440	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_E04580	COG0655	NAD(P)H dehydrogenase (quinone) activity
BZL39_E04590	COG0534	Mate efflux family protein
BZL39_E04640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZL39_E04670	COG1024	Enoyl-CoA hydratase
BZL39_E04720	COG0515	serine threonine protein kinase
BZL39_E04720	COG2815	serine threonine protein kinase
BZL39_E04740	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BZL39_E04760	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BZL39_E04770	COG0051	transcription antitermination factor activity, RNA binding
BZL39_E04880	COG0352	thiamine-phosphate diphosphorylase activity
BZL39_E04950	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BZL39_E04990	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BZL39_E05000	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BZL39_E05070	COG1546	Belongs to the CinA family
BZL39_E05070	COG1058	Belongs to the CinA family
BZL39_E05100	COG0463	Glycosyl transferase, family 2
BZL39_E05140	COG0736	holo-[acyl-carrier-protein] synthase activity
BZL39_E05160	COG1131	(ABC) transporter
BZL39_E05160	COG0842	Transport permease protein
BZL39_E05160	COG1716	ATPase activity
BZL39_E05210	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BZL39_E05220	COG0515	serine threonine protein kinase
BZL39_E05270	COG0326	Molecular chaperone. Has ATPase activity
BZL39_E05350	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BZL39_E05380	COG2271	Major facilitator Superfamily
BZL39_E05390	COG0514	ATP-dependent DNA helicase (RecQ)
BZL39_E05460	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_E05540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BZL39_E05590	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_E05630	COG0288	reversible hydration of carbon dioxide
BZL39_E05690	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BZL39_E05700	COG0251	oxidation-reduction process
BZL39_E05780	COG0484	heat shock protein binding
BZL39_E05830	COG0612	Peptidase, M16
BZL39_E05910	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BZL39_E05970	COG1643	Atp-dependent helicase
BZL39_E06000	COG0318	PFAM AMP-dependent synthetase and ligase
BZL39_E06020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_E06040	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BZL39_E06050	COG0756	dUTP diphosphatase activity
BZL39_E06130	COG0307	riboflavin synthase, alpha
BZL39_E06170	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BZL39_E06180	COG1196	nuclear chromosome segregation
BZL39_E06190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BZL39_E06370	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_E06380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZL39_E06380	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZL39_E06410	COG2815	serine threonine protein kinase
BZL39_E06410	COG0515	serine threonine protein kinase
BZL39_E06480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_E06500	COG0484	heat shock protein binding
BZL39_E06560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BZL39_E06590	COG0527	aspartate kinase activity
BZL39_E06660	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BZL39_E06680	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BZL39_E06850	COG3118	belongs to the thioredoxin family
BZL39_E06870	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BZL39_E06990	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BZL39_E07090	COG1131	(ABC) transporter
BZL39_E07090	COG0842	Transport permease protein
BZL39_E07090	COG1716	ATPase activity
BZL39_F00110	COG0833	amino acid
BZL39_F00120	COG0469	pyruvate kinase activity
BZL39_F00160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BZL39_F00170	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BZL39_F00170	COG3266	domain, Protein
BZL39_F00180	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BZL39_F00250	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BZL39_F00380	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BZL39_F00470	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_F00630	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BZL39_F00650	COG0626	cystathionine gamma-synthase activity
BZL39_F00680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BZL39_F00820	COG1132	(ABC) transporter
BZL39_F00830	COG2815	serine threonine protein kinase
BZL39_F00830	COG0515	serine threonine protein kinase
BZL39_F00850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BZL39_F00850	COG0678	peroxiredoxin activity
BZL39_F01060	COG0515	serine threonine protein kinase
BZL39_F01060	COG2815	serine threonine protein kinase
BZL39_F01110	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
BZL39_F01210	COG5265	(ABC) transporter
BZL39_F01320	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BZL39_F01340	COG0154	amidase activity
BZL39_F01350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_F01380	COG0302	gtp cyclohydrolase
BZL39_F01390	COG1357	PFAM Pentapeptide repeats (8 copies)
BZL39_F01390	COG0515	serine threonine protein kinase
BZL39_F01420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_F01420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_F01550	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BZL39_F01620	COG0204	Acyl-transferase
BZL39_F01710	COG0443	Heat shock 70 kDa protein
BZL39_F01760	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BZL39_F01920	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BZL39_F01930	COG3961	Belongs to the TPP enzyme family
BZL39_F01950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZL39_F01960	COG0560	Phosphoserine phosphatase
BZL39_F01960	COG3830	Belongs to the UPF0237 family
BZL39_F02000	COG0688	phosphatidylethanolamine metabolic process
BZL39_F02030	COG0513	Belongs to the DEAD box helicase family
BZL39_F02060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BZL39_F02150	COG0475	glutathione-regulated potassium exporter activity
BZL39_F02160	COG0210	DNA helicase
BZL39_F02210	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BZL39_F02280	COG0513	Belongs to the DEAD box helicase family
BZL39_F02370	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BZL39_F02490	COG1612	heme a metabolic process
BZL39_F02550	COG0156	8-amino-7-oxononanoate synthase activity
BZL39_F02560	COG1119	ATPase activity
BZL39_F02640	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_F02650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BZL39_F02680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZL39_F02680	COG1752	Esterase of the alpha-beta hydrolase superfamily
BZL39_F02690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BZL39_F02880	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BZL39_F02910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BZL39_F02930	COG1058	Belongs to the CinA family
BZL39_F02930	COG1546	Belongs to the CinA family
BZL39_F02950	COG0418	dihydroorotase activity
BZL39_F02980	COG1621	beta-fructofuranosidase activity
BZL39_F02990	COG1643	Atp-dependent helicase
BZL39_F03030	COG4178	(ABC) transporter
BZL39_F03110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZL39_F03240	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZL39_F03290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_F03520	COG0495	leucyl-tRNA aminoacylation
BZL39_F03570	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BZL39_F03590	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BZL39_F03600	COG1902	pentaerythritol trinitrate reductase activity
BZL39_F03710	COG0515	serine threonine protein kinase
BZL39_F03710	COG2815	serine threonine protein kinase
BZL39_F03750	COG0523	cobalamin synthesis protein
BZL39_F03760	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZL39_F03790	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BZL39_F03960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BZL39_F04020	COG0439	Biotin carboxylase
BZL39_F04030	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BZL39_F04090	COG0572	uridine kinase
BZL39_F04120	COG1113	amino acid transport
BZL39_F04140	COG0205	6-phosphofructokinase activity
BZL39_F04210	COG0489	protein tyrosine kinase activity
BZL39_F04290	COG0724	RNA recognition motif
BZL39_F04390	COG1185	polyribonucleotide nucleotidyltransferase activity
BZL39_F04410	COG0833	amino acid
BZL39_F04540	COG0149	triose-phosphate isomerase activity
BZL39_F04590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BZL39_F04660	COG0154	amidase activity
BZL39_F04690	COG1222	aaa ATPase
BZL39_F04770	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BZL39_F04870	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZL39_F04870	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BZL39_F04920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BZL39_F04950	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BZL39_F05130	COG0417	DNA replication proofreading
BZL39_F05210	COG0424	maF-like protein
BZL39_F05340	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BZL39_F05400	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BZL39_F05430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BZL39_F05540	COG1444	tRNA N-acetyltransferase activity
BZL39_F05610	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BZL39_F05710	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BZL39_F05830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BZL39_F05830	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BZL39_F05840	COG3104	oligopeptide transport
BZL39_F05940	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BZL39_F05980	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BZL39_F06050	COG0183	Belongs to the thiolase family
BZL39_F06110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BZL39_F06110	COG0519	Catalyzes the synthesis of GMP from XMP
BZL39_F06120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BZL39_F06170	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BZL39_F06180	COG2814	Major facilitator Superfamily
BZL39_F06290	COG0798	PFAM Bile acid sodium symporter
BZL39_F06300	COG3961	Belongs to the TPP enzyme family
BZL39_G00140	COG3961	Belongs to the TPP enzyme family
BZL39_G00150	COG3961	Belongs to the TPP enzyme family
BZL39_G00160	COG0154	amidase activity
BZL39_G00170	COG0439	Biotin carboxylase
BZL39_G00190	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BZL39_G00340	COG0339	signal peptide processing
BZL39_G00380	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BZL39_G00530	COG0545	Peptidyl-prolyl cis-trans isomerase
BZL39_G00560	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BZL39_G00710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BZL39_G00770	COG0833	amino acid
BZL39_G00790	COG0515	serine threonine protein kinase
BZL39_G00790	COG2815	serine threonine protein kinase
BZL39_G00840	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BZL39_G00930	COG1132	(ABC) transporter
BZL39_G00940	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BZL39_G00950	COG1819	glycosyl
BZL39_G01010	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZL39_G01020	COG1902	pentaerythritol trinitrate reductase activity
BZL39_G01060	COG1404	Belongs to the peptidase S8 family
BZL39_G01110	COG0833	amino acid
BZL39_G01120	COG0833	amino acid
BZL39_G01200	COG0484	heat shock protein binding
BZL39_G01310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZL39_G01320	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BZL39_G01410	COG0484	heat shock protein binding
BZL39_G01430	COG0215	cysteine-tRNA ligase activity
BZL39_G01680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BZL39_G01710	COG0753	catalase activity
BZL39_G01970	COG1113	amino acid transport
BZL39_G01990	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BZL39_G02050	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
BZL39_G02070	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BZL39_G02150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BZL39_G02250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BZL39_G02260	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BZL39_G02290	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_G02320	COG0494	nUDIX hydrolase
BZL39_G02490	COG0484	heat shock protein binding
BZL39_G02800	COG0187	DNA topoisomerase II activity
BZL39_G02850	COG0459	protein refolding
BZL39_G02920	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BZL39_G02930	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BZL39_G02980	COG0484	heat shock protein binding
BZL39_G03030	COG1252	NADH dehydrogenase
BZL39_G03150	COG2040	homocysteine
BZL39_G03160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BZL39_G03290	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BZL39_G03430	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BZL39_G03560	COG0473	3-isopropylmalate dehydrogenase activity
BZL39_G03610	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BZL39_G03630	COG2815	serine threonine protein kinase
BZL39_G03630	COG0515	serine threonine protein kinase
BZL39_G03650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BZL39_G03650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BZL39_G03660	COG0473	3-isopropylmalate dehydrogenase activity
BZL39_G03900	COG2091	lysine biosynthetic process via aminoadipic acid
BZL39_G03930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_G03930	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_G03990	COG3265	gluconokinase activity
BZL39_G04010	COG0667	Aldo Keto reductase
BZL39_G04080	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BZL39_G04110	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BZL39_G04130	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BZL39_G04290	COG0724	RNA recognition motif
BZL39_G04340	COG0724	RNA recognition motif
BZL39_G04380	COG0113	porphobilinogen synthase activity
BZL39_G04400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_G04400	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_G04430	COG1335	isochorismatase
BZL39_G04800	COG1741	Belongs to the pirin family
BZL39_G04900	COG0114	fumarate hydratase activity
BZL39_G04910	COG0659	secondary active sulfate transmembrane transporter activity
BZL39_G04950	COG0251	oxidation-reduction process
BZL39_G04990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BZL39_G05000	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BZL39_G05050	COG2224	Isocitrate lyase
BZL39_G05090	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BZL39_G05140	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BZL39_G05140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BZL39_G05190	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_G05260	COG0006	proline dipeptidase activity
BZL39_G05300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BZL39_G05330	COG0167	dihydroorotate dehydrogenase activity
BZL39_G05370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BZL39_G05420	COG0656	L-ascorbic acid biosynthetic process
BZL39_G05430	COG0277	FAD linked oxidase domain protein
BZL39_G05450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_G05560	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
BZL39_G05610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BZL39_G05670	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BZL39_G05860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BZL39_G05860	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BZL39_G05960	COG0443	Heat shock 70 kDa protein
BZL39_G06090	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BZL39_G06110	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BZL39_G06140	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BZL39_G06220	COG0484	heat shock protein binding
BZL39_G06230	COG0625	glutathione transferase activity
BZL39_G06330	COG1404	Belongs to the peptidase S8 family
BZL39_G06340	COG3579	cysteine-type endopeptidase activity
BZL39_G06360	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BZL39_G06400	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BZL39_G06450	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BZL39_G06470	COG0833	amino acid
BZL39_G06480	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_H00130	COG1716	ATPase activity
BZL39_H00130	COG1131	(ABC) transporter
BZL39_H00130	COG0842	Transport permease protein
BZL39_H00350	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BZL39_H00370	COG3118	belongs to the thioredoxin family
BZL39_H00530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BZL39_H00550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BZL39_H00610	COG0527	aspartate kinase activity
BZL39_H00640	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BZL39_H00700	COG0484	heat shock protein binding
BZL39_H00720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_H00790	COG2815	serine threonine protein kinase
BZL39_H00790	COG0515	serine threonine protein kinase
BZL39_H00820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BZL39_H00820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BZL39_H00830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_H01010	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BZL39_H01020	COG1196	nuclear chromosome segregation
BZL39_H01030	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BZL39_H01070	COG0307	riboflavin synthase, alpha
BZL39_H01150	COG0756	dUTP diphosphatase activity
BZL39_H01160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BZL39_H01180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_H01200	COG0318	PFAM AMP-dependent synthetase and ligase
BZL39_H01230	COG1643	Atp-dependent helicase
BZL39_H01290	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BZL39_H01570	COG1183	phosphatidylcholine synthase activity
BZL39_H01590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BZL39_H01600	COG0058	SHG alpha-glucan phosphorylase activity
BZL39_H01700	COG3346	SURF1 family
BZL39_H01750	COG0667	Aldo Keto reductase
BZL39_H01890	COG0004	ammonium transporteR
BZL39_H01970	COG0367	asparagine synthase
BZL39_H02000	COG0024	Methionine aminopeptidase
BZL39_H02190	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BZL39_H02240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BZL39_H02250	COG0443	Heat shock 70 kDa protein
BZL39_H02310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BZL39_H02340	COG0450	alkyl hydroperoxide reductase
BZL39_H02360	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BZL39_H02400	COG0515	serine threonine protein kinase
BZL39_H02400	COG2815	serine threonine protein kinase
BZL39_H02470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BZL39_H02510	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BZL39_H02510	COG1648	precorrin-2 dehydrogenase activity
BZL39_H02590	COG0513	Belongs to the DEAD box helicase family
BZL39_H02670	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZL39_H02870	COG0656	L-ascorbic acid biosynthetic process
BZL39_H02950	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BZL39_H02970	COG1362	aminopeptidase activity
BZL39_H02980	COG0626	cystathionine gamma-synthase activity
BZL39_H03080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BZL39_H03120	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BZL39_H03170	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BZL39_H03340	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BZL39_H03360	COG0842	Transport permease protein
BZL39_H03360	COG1716	ATPase activity
BZL39_H03360	COG1131	(ABC) transporter
BZL39_H03370	COG1131	(ABC) transporter
BZL39_H03370	COG0842	Transport permease protein
BZL39_H03370	COG1716	ATPase activity
BZL39_H03410	COG0515	serine threonine protein kinase
BZL39_H03410	COG2815	serine threonine protein kinase
BZL39_H03420	COG4221	oxidoreductase activity
BZL39_H03530	COG1785	Belongs to the alkaline phosphatase family
BZL39_H03570	COG0753	catalase activity
BZL39_H03630	COG0724	RNA recognition motif
BZL39_H03640	COG0515	serine threonine protein kinase
BZL39_H03660	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BZL39_H03740	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BZL39_H03780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BZL39_H03860	COG0417	DNA replication proofreading
BZL39_H03890	COG2897	thiosulfate sulfurtransferase activity
BZL39_H03920	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BZL39_H03970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BZL39_H04080	COG0585	pseudouridine synthase activity
BZL39_H04100	COG0285	dihydrofolate synthase activity
BZL39_H04110	COG0515	serine threonine protein kinase
BZL39_H04110	COG2815	serine threonine protein kinase
BZL39_H04180	COG3842	ATPase activity
BZL39_H04250	COG0515	serine threonine protein kinase
BZL39_H04260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BZL39_H04270	COG0515	serine threonine protein kinase
BZL39_H04270	COG2815	serine threonine protein kinase
BZL39_H04320	COG0822	iron-sulfur transferase activity
BZL39_H04380	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BZL39_H04420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BZL39_H04440	COG1610	YqeY-like protein
BZL39_H04540	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BZL39_H04630	COG0459	protein refolding
BZL39_H04640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BZL39_H04650	COG4285	Biotin-protein ligase, N terminal
BZL39_H04660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BZL39_H04660	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BZL39_H04670	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZL39_H04710	COG2814	Major facilitator Superfamily
BZL39_H04720	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BZL39_H04830	COG1053	succinate dehydrogenase
BZL39_H04890	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BZL39_H04910	COG3474	cytochrome
BZL39_H04920	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
BZL39_H04970	COG4221	oxidoreductase activity
BZL39_H05020	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BZL39_H05040	COG0443	Heat shock 70 kDa protein
BZL39_H05060	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BZL39_H05100	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_H05180	COG2224	Isocitrate lyase
BZL39_H05210	COG0006	proline dipeptidase activity
BZL39_H05310	COG0101	tRNA pseudouridine synthase activity
BZL39_H05320	COG0513	Belongs to the DEAD box helicase family
BZL39_H05400	COG0228	four-way junction DNA binding
BZL39_H05450	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BZL39_H05500	COG1196	nuclear chromosome segregation
BZL39_H05590	COG0484	heat shock protein binding
BZL39_H05660	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BZL39_H05710	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BZL39_H05860	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BZL39_H05890	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BZL39_H06030	COG2814	Major facilitator Superfamily
BZL39_H06080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BZL39_H06090	COG2132	Multicopper oxidase
BZL39_H06310	COG4336	lyase activity
BZL39_H06330	COG0154	amidase activity
BZL39_H06370	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BZL39_H06380	COG1454	alcohol dehydrogenase
BZL39_H06390	COG3961	Belongs to the TPP enzyme family
BZL39_H06400	COG3961	Belongs to the TPP enzyme family
BZL39_I00140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BZL39_I00180	COG1132	(ABC) transporter
BZL39_I00230	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BZL39_I00330	COG0105	UTP biosynthetic process
BZL39_I00350	COG0667	Aldo Keto reductase
BZL39_I00610	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_I00690	COG0191	fructose-bisphosphate aldolase activity
BZL39_I00730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BZL39_I00850	COG2124	cytochrome p450
BZL39_I00980	COG0012	GTP binding
BZL39_I01040	COG0515	serine threonine protein kinase
BZL39_I01040	COG1357	PFAM Pentapeptide repeats (8 copies)
BZL39_I01110	COG0405	Gamma-glutamyltransferase
BZL39_I01150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BZL39_I01240	COG2815	serine threonine protein kinase
BZL39_I01240	COG0515	serine threonine protein kinase
BZL39_I01250	COG0488	(ABC) transporter
BZL39_I01280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BZL39_I01300	COG0538	isocitrate dehydrogenase activity
BZL39_I01310	COG0440	acetolactate synthase activity
BZL39_I01320	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BZL39_I01390	COG1104	cysteine desulfurase activity
BZL39_I01400	COG0473	3-isopropylmalate dehydrogenase activity
BZL39_I01440	COG0484	heat shock protein binding
BZL39_I01450	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BZL39_I01550	COG0655	NAD(P)H dehydrogenase (quinone) activity
BZL39_I01600	COG1584	GPR1 FUN34 yaaH family protein
BZL39_I01620	COG1584	GPR1 FUN34 yaaH family protein
BZL39_I01650	COG1136	(ABC) transporter
BZL39_I01710	COG2814	Major facilitator Superfamily
BZL39_I01740	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BZL39_I01820	COG0481	GTPase activity
BZL39_I01830	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_I01920	COG0515	serine threonine protein kinase
BZL39_I02080	COG2233	PERMEase
BZL39_I02090	COG0085	RNA polymerase activity
BZL39_I02110	COG0009	L-threonylcarbamoyladenylate synthase
BZL39_I02240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_I02270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZL39_I02330	COG0028	Belongs to the TPP enzyme family
BZL39_I02340	COG0017	Asparaginyl-tRNA synthetase
BZL39_I02380	COG2814	Major facilitator Superfamily
BZL39_I02400	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BZL39_I02430	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BZL39_I02530	COG0515	serine threonine protein kinase
BZL39_I02530	COG2815	serine threonine protein kinase
BZL39_I02810	COG0656	L-ascorbic acid biosynthetic process
BZL39_I02880	COG0504	CTP synthase activity
BZL39_I02940	COG1953	Uracil, thiamine, allantoin
BZL39_I03180	COG0484	heat shock protein binding
BZL39_I03210	COG0515	serine threonine protein kinase
BZL39_I03210	COG2815	serine threonine protein kinase
BZL39_I03250	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BZL39_I03470	COG2815	serine threonine protein kinase
BZL39_I03470	COG0515	serine threonine protein kinase
BZL39_I03520	COG0626	cystathionine gamma-synthase activity
BZL39_I03530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BZL39_I03590	COG0123	including yeast histone deacetylase and acetoin utilization protein
BZL39_I03700	COG0515	serine threonine protein kinase
BZL39_I03790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BZL39_I04050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BZL39_I04110	COG2264	protein methyltransferase activity
BZL39_I04120	COG4266	Belongs to the allantoicase family
BZL39_I04140	COG0626	cystathionine gamma-synthase activity
BZL39_I04290	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BZL39_I04330	COG0460	homoserine dehydrogenase
BZL39_I04330	COG0527	aspartate kinase activity
BZL39_I04410	COG0095	Lipoate-protein ligase
BZL39_I04490	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BZL39_I04750	COG0070	glutamate synthase
BZL39_I04750	COG0067	glutamate synthase
BZL39_I04750	COG0069	glutamate synthase activity
BZL39_I04780	COG0277	FAD linked oxidase domain protein
BZL39_I04820	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BZL39_I04830	COG0442	prolyl-tRNA aminoacylation
BZL39_I04930	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BZL39_I05000	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BZL39_I05220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BZL39_I05270	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BZL39_I05270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BZL39_I05300	COG0484	heat shock protein binding
BZL39_I05310	COG2814	Major facilitator Superfamily
BZL39_I05340	COG0300	oxidoreductase activity
BZL39_I05360	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BZL39_I05380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_I05440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BZL39_I05470	COG0508	dehydrogenase complex catalyzes the overall conversion of
BZL39_I05480	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BZL39_I05520	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BZL39_I05550	COG0193	aminoacyl-tRNA hydrolase activity
BZL39_I05570	COG0477	Major facilitator Superfamily
BZL39_I05630	COG3425	synthase
BZL39_I05820	COG3961	Belongs to the TPP enzyme family
BZL39_I05830	COG0277	FAD linked oxidase domain protein
BZL39_I05840	COG0667	Aldo Keto reductase
BZL39_I05850	COG2271	Major facilitator Superfamily
BZL39_I05890	COG0798	PFAM Bile acid sodium symporter
BZL39_J00120	COG1454	alcohol dehydrogenase
BZL39_J00130	COG0523	cobalamin synthesis protein
BZL39_J00140	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BZL39_J00220	COG0415	Belongs to the DNA photolyase family
BZL39_J00240	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_J00450	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BZL39_J00570	COG0833	amino acid
BZL39_J00660	COG1902	pentaerythritol trinitrate reductase activity
BZL39_J00670	COG0045	succinate-CoA ligase (ADP-forming) activity
BZL39_J00750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BZL39_J00800	COG2815	serine threonine protein kinase
BZL39_J00800	COG0515	serine threonine protein kinase
BZL39_J00830	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BZL39_J00900	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_J00910	COG0557	exoribonuclease II activity
BZL39_J00930	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_J00980	COG1205	dead DEAH box helicase
BZL39_J00980	COG1111	helicase
BZL39_J01050	COG0483	inositol monophosphate 1-phosphatase activity
BZL39_J01070	COG2124	cytochrome p450
BZL39_J01070	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BZL39_J01140	COG0483	inositol monophosphate 1-phosphatase activity
BZL39_J01190	COG1914	H( )-stimulated, divalent metal cation uptake system
BZL39_J01250	COG0534	Mate efflux family protein
BZL39_J01260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BZL39_J01280	COG0823	Involved in the tonB-independent uptake of proteins
BZL39_J01280	COG1506	peptidase
BZL39_J01310	COG0083	homoserine kinase activity
BZL39_J01370	COG0542	response to heat
BZL39_J01440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BZL39_J01500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BZL39_J01530	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BZL39_J01540	COG0137	argininosuccinate synthase activity
BZL39_J01550	COG0588	phosphoglycerate mutase activity
BZL39_J01570	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BZL39_J01570	COG0352	thiamine-phosphate diphosphorylase activity
BZL39_J01570	COG0351	phosphomethylpyrimidine kinase
BZL39_J01600	COG0515	serine threonine protein kinase
BZL39_J01600	COG2815	serine threonine protein kinase
BZL39_J01620	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BZL39_J01650	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BZL39_J01670	COG0457	Tetratricopeptide repeat
BZL39_J01670	COG0515	serine threonine protein kinase
BZL39_J01740	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BZL39_J01750	COG0135	phosphoribosylanthranilate isomerase activity
BZL39_J01820	COG1012	belongs to the aldehyde dehydrogenase family
BZL39_J01850	COG0142	geranyltranstransferase activity
BZL39_J02000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_J02010	COG1085	galactose-1-phosphate uridylyltransferase
BZL39_J02020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BZL39_J02030	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BZL39_J02170	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BZL39_J02200	COG0572	uridine kinase
BZL39_J02210	COG0459	protein refolding
BZL39_J02250	COG0318	PFAM AMP-dependent synthetase and ligase
BZL39_J02270	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BZL39_J02310	COG0259	pyridoxamine-phosphate oxidase activity
BZL39_J02340	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BZL39_J02380	COG0575	Belongs to the CDS family
BZL39_J02390	COG0515	serine threonine protein kinase
BZL39_J02420	COG0012	GTP binding
BZL39_J02430	COG1999	signal sequence binding
BZL39_J02490	COG1716	ATPase activity
BZL39_J02490	COG0842	Transport permease protein
BZL39_J02490	COG1131	(ABC) transporter
BZL39_J02530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BZL39_J02550	COG2815	serine threonine protein kinase
BZL39_J02550	COG0515	serine threonine protein kinase
BZL39_J02560	COG1362	aminopeptidase activity
BZL39_J02570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BZL39_J02610	COG2814	Major facilitator Superfamily
BZL39_J02620	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BZL39_J02680	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BZL39_J02710	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BZL39_J02770	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BZL39_J02780	COG2815	serine threonine protein kinase
BZL39_J02780	COG0515	serine threonine protein kinase
BZL39_J02840	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BZL39_J02900	COG0515	serine threonine protein kinase
BZL39_J02910	COG0033	Phosphoglucomutase
BZL39_J02950	COG0028	Belongs to the TPP enzyme family
BZL39_J03000	COG0285	dihydrofolate synthase activity
BZL39_J03340	COG0203	ribosomal protein L17
BZL39_J03350	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BZL39_J03400	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BZL39_J03420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BZL39_J03520	COG0484	heat shock protein binding
BZL39_J03540	COG1196	nuclear chromosome segregation
BZL39_J03680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_J03680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BZL39_J03700	COG2814	Major facilitator Superfamily
BZL39_J03750	COG0386	Belongs to the glutathione peroxidase family
BZL39_J03760	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BZL39_J03780	COG1160	GTP binding
BZL39_J03800	COG0477	Major facilitator Superfamily
BZL39_J03810	COG0477	Major facilitator Superfamily
BZL39_J03850	COG0107	imidazoleglycerol-phosphate synthase activity
BZL39_J03860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BZL39_J03890	COG0724	RNA recognition motif
BZL39_J03960	COG0477	Major facilitator Superfamily
BZL39_J04000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BZL39_J04000	COG0517	IMP dehydrogenase activity
BZL39_J04030	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BZL39_J04210	COG0525	valine-tRNA ligase activity
BZL39_J04240	COG0515	serine threonine protein kinase
BZL39_J04360	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BZL39_J04380	COG0515	serine threonine protein kinase
BZL39_J04420	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BZL39_J04450	COG1902	pentaerythritol trinitrate reductase activity
BZL39_J04460	COG1902	pentaerythritol trinitrate reductase activity
BZL39_J04500	COG0148	phosphopyruvate hydratase activity
BZL39_J04540	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BZL39_J04580	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BZL39_J04630	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BZL39_J04660	COG0363	glucosamine-6-phosphate deaminase activity
BZL39_J04720	COG2217	Heavy metal translocating P-type atpase
BZL39_J04750	COG0180	Tryptophanyl-tRNA synthetase
BZL39_J04850	COG0556	nucleotide-excision repair
BZL39_J05000	COG0515	serine threonine protein kinase
BZL39_J05020	COG1028	Short-chain dehydrogenase reductase Sdr
BZL39_J05090	COG2815	serine threonine protein kinase
BZL39_J05090	COG0515	serine threonine protein kinase
BZL39_J05130	COG1657	PFAM Prenyltransferase squalene oxidase
BZL39_J05270	COG0328	RNA-DNA hybrid ribonuclease activity
BZL39_J05380	COG1132	(ABC) transporter
BZL39_J05400	COG0477	Major facilitator Superfamily
BZL39_J05450	COG0081	regulation of translation
BZL39_J05460	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BZL39_J05490	COG0484	heat shock protein binding
BZL39_J05510	COG0459	protein refolding
BZL39_J05550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BZL39_J05590	COG3118	belongs to the thioredoxin family
BZL39_J05610	COG4221	oxidoreductase activity
BZL39_J05620	COG0076	glutamate decarboxylase activity
BZL39_J05780	COG1902	pentaerythritol trinitrate reductase activity
BZL39_J05810	COG0154	amidase activity
BZL39_J05860	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BZL39_J05870	COG2814	Major facilitator Superfamily
BZL39_J05880	COG2814	Major facilitator Superfamily
BZL39_K00160	COG0667	Aldo Keto reductase
BZL39_K00170	COG1064	alcohol dehydrogenase
BZL39_K00180	COG0667	Aldo Keto reductase
BZL39_K00210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family