locus-tag	class	description
Za10_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Za10_0002	COG0488	(ABC) transporter
Za10_0003	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
Za10_0003	COG2885	chlorophyll binding
Za10_0004	COG4702	Belongs to the UPF0303 family
Za10_0005	COG0670	Belongs to the BI1 family
Za10_0007	COG1058	Belongs to the CinA family
Za10_0007	COG1546	Belongs to the CinA family
Za10_0008	COG0024	Methionine aminopeptidase
Za10_0011	COG0308	aminopeptidase N
Za10_0013	COG2321	neutral zinc metallopeptidase
Za10_0015	COG1280	lysine exporter protein (LysE YggA)
Za10_0016	COG1741	Belongs to the pirin family
Za10_0017	COG0583	DNA-binding transcription factor activity
Za10_0018	COG0655	NAD(P)H dehydrogenase (quinone) activity
Za10_0019	COG2353	YceI-like domain
Za10_0021	COG0668	transmembrane transport
Za10_0022	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Za10_0023	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Za10_0026	COG1660	Displays ATPase and GTPase activities
Za10_0027	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Za10_0028	COG0642	Histidine kinase
Za10_0029	COG0745	RESPONSE REGULATOR receiver
Za10_0031	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
Za10_0033	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Za10_0034	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Za10_0035	COG2244	polysaccharide biosynthetic process
Za10_0037	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Za10_0038	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Za10_0039	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Za10_0040	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Za10_0041	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Za10_0043	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Za10_0043	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Za10_0044	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
Za10_0047	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Za10_0048	COG0321	lipoyl(octanoyl) transferase activity
Za10_0051	COG0602	queuosine metabolic process
Za10_0052	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
Za10_0055	COG2261	transglycosylase associated protein
Za10_0056	COG2223	nitrite transmembrane transporter activity
Za10_0062	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Za10_0063	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Za10_0064	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Za10_0066	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Za10_0068	COG1012	belongs to the aldehyde dehydrogenase family
Za10_0069	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Za10_0069	COG1648	precorrin-2 dehydrogenase activity
Za10_0070	COG0156	8-amino-7-oxononanoate synthase activity
Za10_0073	COG0519	Catalyzes the synthesis of GMP from XMP
Za10_0073	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Za10_0075	COG4948	Mandelate Racemase Muconate Lactonizing
Za10_0076	COG1116	anion transmembrane transporter activity
Za10_0077	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Za10_0078	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Za10_0079	COG4771	TonB-dependent receptor
Za10_0080	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Za10_0082	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
Za10_0083	COG1138	Cytochrome C-type biogenesis protein
Za10_0084	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Za10_0085	COG3088	subunit of a heme lyase
Za10_0090	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Za10_0092	COG2866	Carboxypeptidase
Za10_0093	COG0588	phosphoglycerate mutase activity
Za10_0094	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Za10_0095	COG1064	alcohol dehydrogenase
Za10_0097	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Za10_0104	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Za10_0104	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
Za10_0105	COG0302	gtp cyclohydrolase
Za10_0106	COG4948	Mandelate Racemase Muconate Lactonizing
Za10_0107	COG0359	binds to the 23S rRNA
Za10_0108	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Za10_0109	COG0360	Binds together with S18 to 16S ribosomal RNA
Za10_0110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
Za10_0113	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Za10_0114	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Za10_0115	COG0805	protein transport
Za10_0119	COG0513	Belongs to the DEAD box helicase family
Za10_0121	COG0166	Belongs to the GPI family
Za10_0123	COG3158	transport of potassium into the cell
Za10_0124	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Za10_0128	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Za10_0129	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Za10_0131	COG0156	8-amino-7-oxononanoate synthase activity
Za10_0132	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Za10_0133	COG2814	Major facilitator Superfamily
Za10_0134	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Za10_0135	COG0758	DNA mediated transformation
Za10_0136	COG1754	DNA topoisomerase type I activity
Za10_0136	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Za10_0137	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Za10_0138	COG0756	dUTP diphosphatase activity
Za10_0139	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Za10_0140	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Za10_0141	COG2226	methyltransferase
Za10_0142	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Za10_0147	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Za10_0150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Za10_0151	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Za10_0153	COG2205	protein histidine kinase activity
Za10_0156	COG3724	N-succinylarginine dihydrolase activity
Za10_0157	COG1472	Belongs to the glycosyl hydrolase 3 family
Za10_0159	COG2971	BadF BadG BcrA BcrD
Za10_0161	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Za10_0162	COG1040	competence protein
Za10_0163	COG0745	RESPONSE REGULATOR receiver
Za10_0164	COG0704	Plays a role in the regulation of phosphate uptake
Za10_0166	COG0688	phosphatidylethanolamine metabolic process
Za10_0167	COG1183	phosphatidylcholine synthase activity
Za10_0168	COG1794	racemase activity, acting on amino acids and derivatives
Za10_0170	COG0052	Belongs to the universal ribosomal protein uS2 family
Za10_0171	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Za10_0172	COG0528	UMP kinase activity
Za10_0173	COG0233	cytoplasmic translational termination
Za10_0174	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Za10_0175	COG0575	Belongs to the CDS family
Za10_0176	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Za10_0177	COG0750	zinc metalloprotease
Za10_0178	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Za10_0180	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Za10_0181	COG0254	rRNA binding
Za10_0184	COG0492	ferredoxin-NADP+ reductase activity
Za10_0185	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Za10_0186	COG0440	acetolactate synthase activity
Za10_0187	COG0028	Belongs to the TPP enzyme family
Za10_0188	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Za10_0190	COG1858	cytochrome C peroxidase
Za10_0191	COG0312	modulator of DNA gyrase
Za10_0193	COG0288	reversible hydration of carbon dioxide
Za10_0194	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Za10_0195	COG2867	negative regulation of translational initiation
Za10_0196	COG1546	Belongs to the CinA family
Za10_0196	COG1058	Belongs to the CinA family
Za10_0198	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Za10_0198	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Za10_0201	COG5000	phosphorelay sensor kinase activity
Za10_0202	COG2204	response regulator
Za10_0203	COG0776	regulation of translation
Za10_0208	COG1968	undecaprenyl-diphosphatase activity
Za10_0209	COG1573	uracil-dna glycosylase
Za10_0210	COG1252	NADH dehydrogenase
Za10_0211	COG2917	probably involved in intracellular septation
Za10_0212	COG2807	transmembrane transport
Za10_0214	COG1522	sequence-specific DNA binding
Za10_0216	COG2205	protein histidine kinase activity
Za10_0217	COG0802	atpase or kinase
Za10_0218	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
Za10_0220	COG1074	ATP-dependent DNA helicase activity
Za10_0222	COG0557	exoribonuclease II activity
Za10_0223	COG3956	TIGRFAM MazG family protein
Za10_0225	COG0084	hydrolase, TatD family'
Za10_0227	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Za10_0228	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Za10_0229	COG1686	Belongs to the peptidase S11 family
Za10_0231	COG2951	lytic endotransglycosylase activity
Za10_0232	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
Za10_0233	COG1215	transferase activity, transferring glycosyl groups
Za10_0234	COG1215	transferase activity, transferring glycosyl groups
Za10_0237	COG0335	large ribosomal subunit rRNA binding
Za10_0238	COG0336	Belongs to the RNA methyltransferase TrmD family
Za10_0239	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Za10_0240	COG0228	four-way junction DNA binding
Za10_0241	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Za10_0242	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Za10_0243	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Za10_0244	COG0552	protein localization to endoplasmic reticulum
Za10_0245	COG0484	heat shock protein binding
Za10_0251	COG1842	Phage shock protein A
Za10_0253	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
Za10_0254	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Za10_0257	COG0617	tRNA 3'-terminal CCA addition
Za10_0258	COG5001	Diguanylate cyclase
Za10_0259	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Za10_0260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Za10_0261	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Za10_0262	COG0581	inorganic phosphate transmembrane transporter activity
Za10_0263	COG0573	inorganic phosphate transmembrane transporter activity
Za10_0264	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Za10_0266	COG1970	mechanosensitive ion channel activity
Za10_0268	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
Za10_0271	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Za10_0273	COG0137	argininosuccinate synthase activity
Za10_0275	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Za10_0276	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Za10_0282	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Za10_0283	COG1104	cysteine desulfurase activity
Za10_0284	COG2945	thiolester hydrolase activity
Za10_0285	COG0019	diaminopimelate decarboxylase activity
Za10_0287	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Za10_0288	COG1127	ABC transporter
Za10_0291	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Za10_0292	COG0424	maF-like protein
Za10_0294	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
Za10_0297	COG0277	FAD linked oxidase domain protein
Za10_0298	COG3781	membrane
Za10_0299	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Za10_0301	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Za10_0302	COG0352	thiamine-phosphate diphosphorylase activity
Za10_0302	COG0351	phosphomethylpyrimidine kinase
Za10_0303	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Za10_0304	COG3104	oligopeptide transport
Za10_0305	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Za10_0306	COG0009	L-threonylcarbamoyladenylate synthase
Za10_0307	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Za10_0308	COG0800	Aldolase
Za10_0309	COG0668	transmembrane transport
Za10_0312	COG0071	Belongs to the small heat shock protein (HSP20) family
Za10_0315	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Za10_0316	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Za10_0317	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Za10_0321	COG4172	Belongs to the ABC transporter superfamily
Za10_0322	COG0592	DNA-directed DNA polymerase activity
Za10_0323	COG4206	TonB-dependent receptor
Za10_0325	COG0667	Aldo Keto reductase
Za10_0327	COG3394	polysaccharide catabolic process
Za10_0330	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Za10_0332	COG2252	PERMEase
Za10_0334	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
Za10_0335	COG2814	Major facilitator Superfamily
Za10_0336	COG1566	PFAM secretion protein HlyD family protein
Za10_0339	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
Za10_0342	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Za10_0343	COG2857	Cytochrome c1
Za10_0344	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Za10_0345	COG0723	plastoquinol--plastocyanin reductase activity
Za10_0348	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Za10_0349	COG0408	coproporphyrinogen oxidase activity
Za10_0351	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Za10_0352	COG0740	serine-type endopeptidase activity
Za10_0354	COG0544	peptidyl-prolyl cis-trans isomerase activity
Za10_0356	COG1621	beta-fructofuranosidase activity
Za10_0358	COG1846	Transcriptional regulator
Za10_0359	COG0402	S-adenosylhomocysteine deaminase activity
Za10_0360	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
Za10_0361	COG1448	Aminotransferase
Za10_0362	COG0697	spore germination
Za10_0369	COG3191	aminopeptidase activity
Za10_0370	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Za10_0373	COG1278	Cold shock
Za10_0374	COG0653	protein targeting
Za10_0375	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Za10_0384	COG2217	Heavy metal translocating P-type atpase
Za10_0385	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Za10_0386	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Za10_0392	COG2943	transferase activity, transferring hexosyl groups
Za10_0393	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
Za10_0395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Za10_0398	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Za10_0398	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Za10_0404	COG1199	ATP-dependent helicase activity
Za10_0405	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Za10_0410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Za10_0411	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Za10_0412	COG0840	transmembrane signaling receptor activity
Za10_0413	COG2198	Histidine kinase
Za10_0413	COG0643	Histidine kinase
Za10_0414	COG2201	protein-glutamate methylesterase activity
Za10_0417	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Za10_0420	COG1657	PFAM Prenyltransferase squalene oxidase
Za10_0421	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Za10_0422	COG1562	ergosterol biosynthetic process
Za10_0423	COG1562	ergosterol biosynthetic process
Za10_0424	COG1215	transferase activity, transferring glycosyl groups
Za10_0425	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Za10_0427	COG0305	Participates in initiation and elongation during chromosome replication
Za10_0428	COG0295	cytidine deaminase activity
Za10_0429	COG0717	Belongs to the dCTP deaminase family
Za10_0430	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Za10_0431	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Za10_0433	COG1104	cysteine desulfurase activity
Za10_0435	COG1722	exodeoxyribonuclease VII activity
Za10_0436	COG0142	geranyltranstransferase activity
Za10_0437	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Za10_0438	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Za10_0439	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Za10_0440	COG0259	pyridoxamine-phosphate oxidase activity
Za10_0441	COG2204	response regulator
Za10_0445	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Za10_0447	COG0018	arginyl-trna synthetase
Za10_0448	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Za10_0449	COG0038	chloride channel
Za10_0451	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Za10_0452	COG0849	cell division
Za10_0453	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Za10_0454	COG1181	Belongs to the D-alanine--D-alanine ligase family
Za10_0455	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Za10_0456	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Za10_0457	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Za10_0459	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Za10_0460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Za10_0462	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Za10_0465	COG0275	rRNA processing
Za10_0468	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Za10_0469	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
Za10_0470	COG0720	synthase
Za10_0472	COG1322	Protein conserved in bacteria
Za10_0473	COG0242	peptide deformylase activity
Za10_0474	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Za10_0475	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Za10_0476	COG0101	tRNA pseudouridine synthase activity
Za10_0477	COG1872	DUF167
Za10_0478	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Za10_0479	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Za10_0481	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Za10_0484	COG1129	ABC transporter
Za10_0484	COG0842	Transport permease protein
Za10_0485	COG0842	Transport permease protein
Za10_0487	COG1028	Short-chain dehydrogenase reductase Sdr
Za10_0489	COG1505	serine-type exopeptidase activity
Za10_0491	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Za10_0492	COG0540	Belongs to the ATCase OTCase family
Za10_0497	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Za10_0498	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Za10_0499	COG0154	amidase activity
Za10_0500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Za10_0501	COG0583	DNA-binding transcription factor activity
Za10_0502	COG1538	Outer membrane efflux protein
Za10_0505	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Za10_0508	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Za10_0509	COG2239	Acts as a magnesium transporter
Za10_0510	COG0482	sulfurtransferase activity
Za10_0513	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Za10_0514	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Za10_0518	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Za10_0523	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Za10_0526	COG0564	pseudouridine synthase activity
Za10_0527	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Za10_0533	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Za10_0535	COG2329	Antibiotic biosynthesis monooxygenase
Za10_0536	COG2022	thiamine diphosphate biosynthetic process
Za10_0537	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Za10_0538	COG0511	ligase activity, forming carbon-carbon bonds
Za10_0539	COG0439	Biotin carboxylase
Za10_0542	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Za10_0543	COG0085	RNA polymerase activity
Za10_0545	COG0222	ribosome binding
Za10_0546	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Za10_0547	COG0081	regulation of translation
Za10_0548	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Za10_0551	COG3590	peptidase
Za10_0552	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Za10_0553	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Za10_0554	COG0741	lytic transglycosylase activity
Za10_0556	COG2326	polyphosphate kinase activity
Za10_0557	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Za10_0558	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Za10_0559	COG0248	Ppx GppA phosphatase
Za10_0560	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Za10_0563	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Za10_0564	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Za10_0565	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Za10_0568	COG0318	PFAM AMP-dependent synthetase and ligase
Za10_0572	COG2076	Multidrug Resistance protein
Za10_0575	COG1764	response to oxidative stress
Za10_0576	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Za10_0577	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
Za10_0578	COG0673	inositol 2-dehydrogenase activity
Za10_0579	COG0679	Auxin Efflux Carrier
Za10_0589	COG0473	3-isopropylmalate dehydrogenase activity
Za10_0591	COG0583	DNA-binding transcription factor activity
Za10_0593	COG1381	Involved in DNA repair and RecF pathway recombination
Za10_0594	COG0322	excinuclease ABC activity
Za10_0595	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Za10_0596	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Za10_0598	COG0356	it plays a direct role in the translocation of protons across the membrane
Za10_0603	COG2003	Belongs to the UPF0758 family
Za10_0604	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Za10_0605	COG0484	heat shock protein binding
Za10_0606	COG0443	Heat shock 70 kDa protein
Za10_0609	COG3138	arginine N-succinyltransferase
Za10_0612	COG0726	polysaccharide deacetylase
Za10_0613	COG0628	permease
Za10_0616	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Za10_0617	COG1684	flagellar biosynthetic protein fliR
Za10_0618	COG1987	bacterial-type flagellum assembly
Za10_0622	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Za10_0628	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Za10_0630	COG1677	Flagellar hook-basal body complex protein FliE
Za10_0633	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
Za10_0637	COG0455	bacterial-type flagellum organization
Za10_0643	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Za10_0645	COG1558	bacterial-type flagellum-dependent cell motility
Za10_0646	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Za10_0647	COG1749	Flagellar hook protein flgE
Za10_0649	COG4786	Flagellar basal body rod
Za10_0650	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Za10_0651	COG1706	bacterial-type flagellum-dependent cell motility
Za10_0656	COG1360	Flagellar Motor Protein
Za10_0659	COG0825	malonyl-CoA metabolic process
Za10_0660	COG4974	Belongs to the 'phage' integrase family
Za10_0663	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Za10_0664	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Za10_0667	COG1286	toxin biosynthetic process
Za10_0670	COG0284	orotidine-5'-phosphate decarboxylase activity
Za10_0671	COG0135	phosphoribosylanthranilate isomerase activity
Za10_0672	COG0133	tryptophan synthase activity
Za10_0673	COG0159	tryptophan synthase activity
Za10_0674	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Za10_0676	COG2223	nitrite transmembrane transporter activity
Za10_0677	COG1301	dicarboxylic acid transport
Za10_0678	COG1187	pseudouridine synthase activity
Za10_0679	COG0742	ribosomal rna small subunit methyltransferase
Za10_0681	COG2999	glutathione oxidoreductase activity
Za10_0682	COG1116	anion transmembrane transporter activity
Za10_0683	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Za10_0684	COG2264	protein methyltransferase activity
Za10_0688	COG2814	Major facilitator Superfamily
Za10_0690	COG1643	Atp-dependent helicase
Za10_0691	COG0142	geranyltranstransferase activity
Za10_0692	COG1605	Chorismate mutase
Za10_0692	COG0287	Prephenate dehydrogenase
Za10_0693	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Za10_0695	COG2133	pyrroloquinoline quinone binding
Za10_0696	COG0779	Required for maturation of 30S ribosomal subunits
Za10_0699	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Za10_0699	COG3064	Membrane
Za10_0700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Za10_0701	COG1435	thymidine kinase activity
Za10_0702	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Za10_0703	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Za10_0704	COG1185	polyribonucleotide nucleotidyltransferase activity
Za10_0706	COG0038	chloride channel
Za10_0707	COG0659	secondary active sulfate transmembrane transporter activity
Za10_0708	COG0134	indole-3-glycerol-phosphate synthase activity
Za10_0709	COG0538	isocitrate dehydrogenase activity
Za10_0710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Za10_0711	COG0203	ribosomal protein L17
Za10_0712	COG0202	RNA polymerase activity
Za10_0713	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Za10_0714	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Za10_0715	COG0563	adenylate kinase activity
Za10_0716	COG0201	protein transport
Za10_0717	COG0200	Binds to the 23S rRNA
Za10_0718	COG1841	ribosomal large subunit assembly
Za10_0719	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Za10_0720	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Za10_0721	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Za10_0722	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Za10_0723	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Za10_0724	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Za10_0725	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Za10_0726	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Za10_0727	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Za10_0728	COG0255	Belongs to the universal ribosomal protein uL29 family
Za10_0729	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Za10_0730	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Za10_0731	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Za10_0732	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Za10_0733	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Za10_0734	COG0089	rRNA binding
Za10_0735	COG0088	Forms part of the polypeptide exit tunnel
Za10_0736	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Za10_0737	COG0051	transcription antitermination factor activity, RNA binding
Za10_0738	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Za10_0739	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Za10_0740	COG0049	tRNA binding
Za10_0741	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Za10_0742	COG0671	phosphoesterase, PA-phosphatase related
Za10_0743	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Za10_0744	COG1607	acyl-coa hydrolase
Za10_0745	COG0508	dehydrogenase complex catalyzes the overall conversion of
Za10_0748	COG1956	GAF domain-containing protein
Za10_0750	COG0564	pseudouridine synthase activity
Za10_0751	COG0463	Glycosyl transferase, family 2
Za10_0755	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Za10_0756	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Za10_0757	COG0546	phosphoglycolate phosphatase activity
Za10_0761	COG0174	glutamine synthetase
Za10_0762	COG0347	Belongs to the P(II) protein family
Za10_0763	COG0006	proline dipeptidase activity
Za10_0768	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
Za10_0769	COG1960	acyl-CoA dehydrogenase activity
Za10_0772	COG1494	fructose-1,6-bisphosphatase
Za10_0774	COG5002	protein histidine kinase activity
Za10_0778	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Za10_0778	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Za10_0781	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Za10_0783	COG0583	DNA-binding transcription factor activity
Za10_0785	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Za10_0787	COG0149	triose-phosphate isomerase activity
Za10_0789	COG0504	CTP synthase activity
Za10_0790	COG0442	prolyl-tRNA aminoacylation
Za10_0792	COG1136	(ABC) transporter
Za10_0793	COG1522	sequence-specific DNA binding
Za10_0795	COG2759	Belongs to the formate--tetrahydrofolate ligase family
Za10_0796	COG1160	GTP binding
Za10_0804	COG1372	Participates in initiation and elongation during chromosome replication
Za10_0804	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Za10_0805	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Za10_0813	COG0194	GDP metabolic process
Za10_0816	COG2171	N-acyltransferase activity
Za10_0818	COG0316	Belongs to the HesB IscA family
Za10_0819	COG2151	metal-sulfur cluster biosynthetic enzyme
Za10_0820	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Za10_0821	COG0719	Fe-S assembly protein
Za10_0822	COG0396	ATPase activity
Za10_0823	COG0719	Fe-S assembly protein
Za10_0825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Za10_0826	COG0287	Prephenate dehydrogenase
Za10_0830	COG2884	Cell division ATP-binding protein ftsE
Za10_0833	COG2095	MarC family integral membrane protein
Za10_0834	COG0187	DNA topoisomerase II activity
Za10_0835	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Za10_0836	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Za10_0837	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Za10_0839	COG0842	Transport permease protein
Za10_0841	COG0248	Ppx GppA phosphatase
Za10_0842	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Za10_0844	COG5001	Diguanylate cyclase
Za10_0866	COG1621	beta-fructofuranosidase activity
Za10_0867	COG1621	beta-fructofuranosidase activity
Za10_0869	COG1522	sequence-specific DNA binding
Za10_0870	COG1794	racemase activity, acting on amino acids and derivatives
Za10_0871	COG0837	glucose binding
Za10_0872	COG0129	dihydroxy-acid dehydratase activity
Za10_0873	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Za10_0874	COG0477	Major facilitator Superfamily
Za10_0875	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Za10_0876	COG0343	queuine tRNA-ribosyltransferase activity
Za10_0877	COG0556	nucleotide-excision repair
Za10_0879	COG0772	Belongs to the SEDS family
Za10_0882	COG1792	Involved in formation and maintenance of cell shape
Za10_0884	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Za10_0889	COG1678	Uncharacterized ACR, COG1678
Za10_0890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Za10_0891	COG1923	regulation of RNA biosynthetic process
Za10_0892	COG0004	ammonium transporteR
Za10_0894	COG0312	modulator of DNA gyrase
Za10_0900	COG2894	cell division
Za10_0901	COG0352	thiamine-phosphate diphosphorylase activity
Za10_0902	COG3108	Peptidase M15
Za10_0903	COG0483	inositol monophosphate 1-phosphatase activity
Za10_0904	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Za10_0905	COG0626	cystathionine gamma-synthase activity
Za10_0906	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Za10_0908	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
Za10_0909	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Za10_0910	COG0196	riboflavin kinase activity
Za10_0913	COG1028	Short-chain dehydrogenase reductase Sdr
Za10_0915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Za10_0919	COG1028	Short-chain dehydrogenase reductase Sdr
Za10_0923	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Za10_0926	COG1570	exodeoxyribonuclease VII activity
Za10_0927	COG0151	Belongs to the GarS family
Za10_0929	COG1253	flavin adenine dinucleotide binding
Za10_0930	COG0590	tRNA wobble adenosine to inosine editing
Za10_0931	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Za10_0932	COG2814	Major facilitator Superfamily
Za10_0933	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Za10_0934	COG2733	membrane
Za10_0937	COG1538	Outer membrane efflux protein
Za10_0939	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Za10_0941	COG1278	Cold shock
Za10_0945	COG1137	ATPase activity
Za10_0946	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Za10_0947	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Za10_0948	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Za10_0958	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Za10_0959	COG4133	protoheme IX ABC transporter activity
Za10_0960	COG2205	protein histidine kinase activity
Za10_0961	COG0745	RESPONSE REGULATOR receiver
Za10_0962	COG0277	FAD linked oxidase domain protein
Za10_0963	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Za10_0969	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Za10_0970	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Za10_0971	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Za10_0972	COG0776	regulation of translation
Za10_0974	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Za10_0975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Za10_0976	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Za10_0977	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Za10_0978	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Za10_0979	COG0489	protein tyrosine kinase activity
Za10_0980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Za10_0982	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Za10_0984	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Za10_0985	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Za10_0987	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Za10_0987	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Za10_0988	COG4221	oxidoreductase activity
Za10_0989	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Za10_0990	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Za10_0990	COG2813	Specifically methylates the guanine in position
Za10_0993	COG1329	Transcriptional regulator
Za10_0994	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Za10_0995	COG4581	dead DEAH box helicase
Za10_0996	COG0739	heme binding
Za10_0998	COG0534	Mate efflux family protein
Za10_1000	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Za10_1001	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Za10_1003	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Za10_1004	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Za10_1007	COG0789	Transcriptional regulator
Za10_1008	COG0840	transmembrane signaling receptor activity
Za10_1009	COG0512	Glutamine amidotransferase of anthranilate synthase
Za10_1010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Za10_1011	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Za10_1013	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
Za10_1017	COG1530	ribonuclease E activity
Za10_1021	COG1760	l-serine dehydratase
Za10_1023	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Za10_1024	COG0215	cysteine-tRNA ligase activity
Za10_1026	COG0488	(ABC) transporter
Za10_1027	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Za10_1028	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Za10_1029	COG1830	Aldolase
Za10_1031	COG0126	phosphoglycerate kinase activity
Za10_1032	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Za10_1037	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Za10_1040	COG0584	glycerophosphoryl diester phosphodiesterase
Za10_1041	COG2885	chlorophyll binding
Za10_1042	COG0823	Involved in the tonB-independent uptake of proteins
Za10_1044	COG0848	biopolymer transport protein
Za10_1045	COG0811	peptide transport
Za10_1046	COG0824	Thioesterase
Za10_1047	COG2255	four-way junction helicase activity
Za10_1048	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Za10_1050	COG0632	four-way junction helicase activity
Za10_1051	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Za10_1052	COG0217	transcriptional regulatory protein
Za10_1053	COG3750	Belongs to the UPF0335 family
Za10_1054	COG0469	pyruvate kinase activity
Za10_1056	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Za10_1060	COG1131	(ABC) transporter
Za10_1062	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Za10_1072	COG0671	phosphoesterase, PA-phosphatase related
Za10_1075	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Za10_1078	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Za10_1081	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Za10_1082	COG1151	hydroxylamine reductase activity
Za10_1083	COG1959	2 iron, 2 sulfur cluster binding
Za10_1084	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Za10_1085	COG0512	Glutamine amidotransferase of anthranilate synthase
Za10_1085	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Za10_1086	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Za10_1093	COG0066	3-isopropylmalate dehydratase activity
Za10_1094	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Za10_1095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
Za10_1100	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Za10_1102	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Za10_1104	COG1028	Short-chain dehydrogenase reductase Sdr
Za10_1109	COG0840	transmembrane signaling receptor activity
Za10_1111	COG0643	Histidine kinase
Za10_1111	COG2198	Histidine kinase
Za10_1112	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
Za10_1113	COG2201	protein-glutamate methylesterase activity
Za10_1114	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
Za10_1116	COG0835	chemotaxis
Za10_1117	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Za10_1118	COG1702	phosphate starvation-inducible protein PhoH
Za10_1119	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Za10_1122	COG2999	glutathione oxidoreductase activity
Za10_1130	COG1929	Belongs to the glycerate kinase type-1 family
Za10_1132	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Za10_1133	COG0730	response to heat
Za10_1135	COG0424	maF-like protein
Za10_1137	COG0237	dephospho-CoA kinase activity
Za10_1138	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Za10_1139	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Za10_1140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
Za10_1143	COG2983	Belongs to the UPF0260 family
Za10_1147	COG1715	Restriction endonuclease
Za10_1148	COG0138	bifunctional purine biosynthesis protein purh
Za10_1152	COG0247	lactate metabolic process
Za10_1153	COG1139	Iron-sulfur cluster binding protein
Za10_1159	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Za10_1161	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Za10_1162	COG1420	regulation of RNA biosynthetic process
Za10_1163	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Za10_1164	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Za10_1165	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Za10_1168	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
Za10_1169	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Za10_1170	COG0175	sulfate reduction
Za10_1171	COG1648	precorrin-2 dehydrogenase activity
Za10_1171	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Za10_1172	COG0175	sulfate reduction
Za10_1175	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Za10_1178	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Za10_1180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Za10_1182	COG0412	Dienelactone hydrolase
Za10_1183	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Za10_1184	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Za10_1185	COG4771	TonB-dependent receptor
Za10_1187	COG0667	Aldo Keto reductase
Za10_1188	COG3386	PFAM SMP-30 Gluconolaconase
Za10_1189	COG0445	tRNA wobble uridine modification
Za10_1190	COG0357	Ribosomal RNA small subunit methyltransferase G
Za10_1191	COG1192	Involved in chromosome partitioning
Za10_1192	COG1475	DNA binding
Za10_1193	COG0477	Major facilitator Superfamily
Za10_1196	COG0583	DNA-binding transcription factor activity
Za10_1198	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Za10_1199	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Za10_1204	COG0658	competence protein
Za10_1204	COG2333	competence protein COMEC
Za10_1205	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Za10_1206	COG0372	Belongs to the citrate synthase family
Za10_1207	COG5002	protein histidine kinase activity
Za10_1212	COG0438	transferase activity, transferring glycosyl groups
Za10_1212	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Za10_1213	COG0497	DNA recombination
Za10_1215	COG0459	protein refolding
Za10_1216	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Za10_1217	COG0616	signal peptide processing
Za10_1220	COG1368	sulfuric ester hydrolase activity
Za10_1225	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Za10_1226	COG0156	8-amino-7-oxononanoate synthase activity
Za10_1228	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Za10_1228	COG4106	trans-aconitate 2-methyltransferase activity
Za10_1230	COG0189	ligase activity
Za10_1231	COG0012	GTP binding
Za10_1232	COG0193	aminoacyl-tRNA hydrolase activity
Za10_1233	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Za10_1236	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Za10_1237	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Za10_1238	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Za10_1239	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Za10_1240	COG0181	hydroxymethylbilane synthase activity
Za10_1243	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Za10_1244	COG0416	fatty acid biosynthetic process
Za10_1245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Za10_1247	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Za10_1249	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Za10_1252	COG0612	Peptidase, M16
Za10_1254	COG1335	isochorismatase
Za10_1255	COG3180	Ammonia monooxygenase
Za10_1256	COG1902	pentaerythritol trinitrate reductase activity
Za10_1257	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Za10_1258	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Za10_1259	COG3180	Ammonia monooxygenase
Za10_1261	COG0113	porphobilinogen synthase activity
Za10_1262	COG0525	valine-tRNA ligase activity
Za10_1267	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Za10_1273	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Za10_1287	COG0681	Belongs to the peptidase S26 family
Za10_1291	COG0583	DNA-binding transcription factor activity
Za10_1294	COG0464	growth
Za10_1295	COG1404	Belongs to the peptidase S8 family
Za10_1297	COG4221	oxidoreductase activity
Za10_1299	COG1028	Short-chain dehydrogenase reductase Sdr
Za10_1302	COG2070	2-Nitropropane dioxygenase
Za10_1311	COG2176	DNA-directed DNA polymerase activity
Za10_1316	COG4227	nucleotidyltransferase activity
Za10_1327	COG5433	transposase activity
Za10_1330	COG5433	transposase activity
Za10_1333	COG5489	Protein of unknown function (DUF736)
Za10_1334	COG3550	peptidyl-serine autophosphorylation
Za10_1335	COG3620	sequence-specific DNA binding
Za10_1342	COG1192	Involved in chromosome partitioning
Za10_1347	COG0741	lytic transglycosylase activity
Za10_1356	COG4962	Type ii secretion system protein e
Za10_1359	COG3451	type IV secretory pathway VirB4
Za10_1362	COG3846	protein secretion by the type IV secretion system
Za10_1365	COG2948	multi-organism process
Za10_1368	COG0583	DNA-binding transcription factor activity
Za10_1369	COG0419	ATPase involved in DNA repair
Za10_1370	COG0420	3'-5' exonuclease activity
Za10_1381	COG0583	DNA-binding transcription factor activity
Za10_1385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Za10_1386	COG0716	FMN binding
Za10_1391	COG1120	ATPase activity
Za10_1392	COG2824	Alkylphosphonate utilization operon protein PhnA
Za10_1393	COG0673	inositol 2-dehydrogenase activity
Za10_1397	COG3585	molybdate ion transport
Za10_1400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Za10_1401	COG1104	cysteine desulfurase activity
Za10_1407	COG1433	Dinitrogenase iron-molybdenum cofactor
Za10_1408	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Za10_1409	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Za10_1410	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Za10_1411	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
Za10_1412	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
Za10_1415	COG5554	nitrogen fixation
Za10_1417	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Za10_1418	COG0535	radical SAM domain protein
Za10_1419	COG3604	Transcriptional regulator
Za10_1421	COG4657	Part of a membrane complex involved in electron transport
Za10_1422	COG2878	Part of a membrane complex involved in electron transport
Za10_1424	COG4658	electron transport chain
Za10_1429	COG0110	maltose O-acetyltransferase activity
Za10_1430	COG0546	phosphoglycolate phosphatase activity
Za10_1431	COG0531	amino acid
Za10_1433	COG0776	regulation of translation
Za10_1435	COG0539	negative regulation of cytoplasmic translation
Za10_1436	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Za10_1437	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Za10_1439	COG0583	DNA-binding transcription factor activity
Za10_1440	COG0129	dihydroxy-acid dehydratase activity
Za10_1442	COG1132	(ABC) transporter
Za10_1446	COG0668	transmembrane transport
Za10_1453	COG0656	L-ascorbic acid biosynthetic process
Za10_1454	COG1063	alcohol dehydrogenase
Za10_1455	COG1979	alcohol dehydrogenase
Za10_1456	COG0165	Argininosuccinate lyase
Za10_1458	COG0019	diaminopimelate decarboxylase activity
Za10_1461	COG2989	Protein conserved in bacteria
Za10_1463	COG0792	nuclease activity
Za10_1464	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
Za10_1466	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Za10_1467	COG3265	gluconokinase activity
Za10_1468	COG2610	gluconate transmembrane transporter activity
Za10_1469	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Za10_1470	COG1012	belongs to the aldehyde dehydrogenase family
Za10_1476	COG2853	Lipoprotein
Za10_1480	COG1410	methionine synthase
Za10_1480	COG0646	methionine synthase
Za10_1482	COG0481	GTPase activity
Za10_1484	COG3275	phosphorelay sensor kinase activity
Za10_1485	COG3279	Response regulator of the LytR AlgR family
Za10_1488	COG0583	DNA-binding transcription factor activity
Za10_1490	COG1045	serine acetyltransferase
Za10_1493	COG0436	Aminotransferase
Za10_1494	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Za10_1495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Za10_1498	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
Za10_1500	COG1758	RNA polymerase activity
Za10_1501	COG1940	carbohydrate kinase activity
Za10_1507	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Za10_1509	COG0628	permease
Za10_1510	COG0681	Belongs to the peptidase S26 family
Za10_1511	COG0736	holo-[acyl-carrier-protein] synthase activity
Za10_1512	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Za10_1513	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Za10_1516	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Za10_1517	COG1674	ftsk spoiiie
Za10_1518	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Za10_1520	COG0708	Exodeoxyribonuclease III
Za10_1522	COG1733	regulation of RNA biosynthetic process
Za10_1526	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Za10_1527	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
Za10_1528	COG1295	ribonuclease BN
Za10_1529	COG0484	heat shock protein binding
Za10_1530	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Za10_1531	COG0354	folic acid binding
Za10_1532	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Za10_1534	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Za10_1536	COG0252	asparaginase activity
Za10_1538	COG2985	domain, Protein
Za10_1541	COG0077	Prephenate dehydratase
Za10_1542	COG1194	a g-specific adenine glycosylase
Za10_1545	COG0656	L-ascorbic acid biosynthetic process
Za10_1551	COG0793	Belongs to the peptidase S41A family
Za10_1553	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Za10_1554	COG0799	negative regulation of ribosome biogenesis
Za10_1555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Za10_1556	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Za10_1559	COG0037	tRNA processing
Za10_1563	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Za10_1566	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Za10_1568	COG3386	PFAM SMP-30 Gluconolaconase
Za10_1569	COG1573	uracil-dna glycosylase
Za10_1571	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Za10_1573	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Za10_1574	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
Za10_1576	COG0180	Tryptophanyl-tRNA synthetase
Za10_1578	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Za10_1581	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
Za10_1584	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Za10_1589	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Za10_1590	COG0706	membrane insertase activity
Za10_1591	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Za10_1592	COG0594	ribonuclease P activity
Za10_1594	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Za10_1598	COG0505	Belongs to the CarA family
Za10_1600	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Za10_1606	COG0148	phosphopyruvate hydratase activity
Za10_1608	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
Za10_1609	COG0508	dehydrogenase complex catalyzes the overall conversion of
Za10_1609	COG0022	dehydrogenase e1 component
Za10_1611	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Za10_1611	COG3453	Protein conserved in bacteria
Za10_1613	COG0328	RNA-DNA hybrid ribonuclease activity
Za10_1614	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Za10_1616	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Za10_1617	COG1454	alcohol dehydrogenase
Za10_1619	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Za10_1620	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Za10_1621	COG1127	ABC transporter
Za10_1623	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Za10_1626	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Za10_1627	COG0187	DNA topoisomerase II activity
Za10_1631	COG1028	Short-chain dehydrogenase reductase Sdr
Za10_1633	COG4221	oxidoreductase activity
Za10_1637	COG1294	oxidase, subunit
Za10_1638	COG1271	oxidase subunit
Za10_1640	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
Za10_1643	COG1742	UPF0060 membrane protein
Za10_1646	COG1051	belongs to the nudix hydrolase family
Za10_1647	COG4221	oxidoreductase activity
Za10_1650	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Za10_1653	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
Za10_1654	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Za10_1655	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Za10_1656	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Za10_1658	COG1657	PFAM Prenyltransferase squalene oxidase
Za10_1663	COG0629	single-stranded DNA binding
Za10_1666	COG0587	DNA-directed DNA polymerase activity
Za10_1672	COG0047	phosphoribosylformylglycinamidine synthase activity
Za10_1673	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Za10_1674	COG0517	IMP dehydrogenase activity
Za10_1674	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
Za10_1675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Za10_1678	COG1538	Outer membrane efflux protein
Za10_1683	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Za10_1685	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Za10_1686	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Za10_1688	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Za10_1689	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Za10_1689	COG0072	phenylalanine-tRNA ligase activity
Za10_1690	COG5265	(ABC) transporter
Za10_1692	COG2890	protein-(glutamine-N5) methyltransferase activity
Za10_1693	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Za10_1694	COG0124	histidyl-tRNA synthetase
Za10_1695	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Za10_1698	COG0131	Imidazoleglycerol-phosphate dehydratase
Za10_1699	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Za10_1700	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Za10_1701	COG0107	imidazoleglycerol-phosphate synthase activity
Za10_1702	COG0140	phosphoribosyl-ATP diphosphatase activity
Za10_1704	COG0531	amino acid
Za10_1705	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Za10_1706	COG2096	Adenosyltransferase
Za10_1707	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Za10_1711	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Za10_1712	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Za10_1713	COG2199	diguanylate cyclase activity
Za10_1713	COG2200	EAL domain
Za10_1716	COG0210	DNA helicase
Za10_1718	COG0045	succinate-CoA ligase (ADP-forming) activity
Za10_1721	COG0363	glucosamine-6-phosphate deaminase activity
Za10_1727	COG0814	amino acid
Za10_1737	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Za10_1738	COG2814	Major facilitator Superfamily
Za10_1740	COG0415	Belongs to the DNA photolyase family
Za10_1741	COG0246	Mannitol dehydrogenase
Za10_1744	COG0752	glycyl-tRNA synthetase alpha subunit
Za10_1746	COG2244	polysaccharide biosynthetic process
Za10_1750	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Za10_1754	COG0495	leucyl-tRNA aminoacylation
Za10_1761	COG1597	lipid kinase activity
Za10_1762	COG2003	Belongs to the UPF0758 family
Za10_1763	COG0352	thiamine-phosphate diphosphorylase activity
Za10_1765	COG0612	Peptidase, M16
Za10_1766	COG0612	Peptidase, M16
Za10_1767	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Za10_1768	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Za10_1769	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Za10_1770	COG0513	Belongs to the DEAD box helicase family
Za10_1772	COG1214	PFAM Peptidase M22, glycoprotease
Za10_1774	COG4957	zinc ion binding
Za10_1776	COG2193	ferroxidase activity
Za10_1780	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Za10_1781	COG0596	Alpha beta hydrolase
Za10_1782	COG0784	Response regulator, receiver
Za10_1784	COG0739	heme binding
Za10_1785	COG0316	Belongs to the HesB IscA family
Za10_1786	COG0708	Exodeoxyribonuclease III
Za10_1798	COG0405	Gamma-glutamyltransferase
Za10_1802	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Za10_1803	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Za10_1808	COG0571	ribonuclease III activity
Za10_1810	COG0300	oxidoreductase activity
Za10_1813	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Za10_1814	COG3706	GGDEF domain
Za10_1815	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Za10_1819	COG3961	Belongs to the TPP enzyme family
Za10_1820	COG0268	Binds directly to 16S ribosomal RNA
Za10_1826	COG3077	Addiction module antitoxin, RelB DinJ family
Za10_1828	COG3654	unkown
Za10_1832	COG1192	Involved in chromosome partitioning
Za10_1838	COG1002	Type II restriction enzyme, methylase subunits
Za10_1839	COG1061	Type III restriction enzyme res subunit
Za10_1840	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Za10_1844	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Za10_1846	COG3041	Addiction module toxin RelE StbE family
Za10_1847	COG1192	Involved in chromosome partitioning
Za10_1850	COG3311	Transcriptional regulator
Za10_1863	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Za10_1868	COG1215	transferase activity, transferring glycosyl groups
Za10_1869	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
Za10_1872	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
Za10_1877	COG1132	(ABC) transporter
Za10_1878	COG1132	(ABC) transporter
Za10_1883	COG1028	Short-chain dehydrogenase reductase Sdr
Za10_1885	COG3041	Addiction module toxin RelE StbE family
Za10_1895	COG3293	Transposase
Za10_1896	COG3077	Addiction module antitoxin, RelB DinJ family
Za10_1897	COG2026	Addiction module toxin, RelE StbE family
Za10_1903	COG1518	maintenance of DNA repeat elements
Za10_1904	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Za10_1905	COG3293	Transposase
Za10_1912	COG3041	Addiction module toxin RelE StbE family
Za10_1913	COG3077	Addiction module antitoxin, RelB DinJ family