locus-tag	class	description
A254_00002	ENOG4105C5H	ABC transporter
A254_00005	ENOG4105HFZ	Membrane
A254_00006	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
A254_00007	ENOG4105CEV	competence damage-inducible protein
A254_00008	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
A254_00009	ENOG4105C5W	Aldolase
A254_00011	ENOG4105CD8	aminopeptidase N
A254_00014	ENOG4105CGZ	zinc metallopeptidase
A254_00016	ENOG410829K	Lysine exporter protein (Lyse ygga)
A254_00018	ENOG4105CC0	LysR family Transcriptional regulator
A254_00020	ENOG4108YYC	ycei family
A254_00021	ENOG4105D8X	mechanosensitive ion channel
A254_00023	ENOG4108RWN	rrna methyltransferase
A254_00027	ENOG4107UZ6	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr)
A254_00028	ENOG4105EB3	Histidine kinase
A254_00029	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A254_00031	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A254_00033	ENOG4108GH0	ATP-binding protein yghT
A254_00034	ENOG4106FPV	ATP-binding protein YghR
A254_00035	ENOG4108S55	polysaccharide biosynthesis protein
A254_00039	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A254_00040	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A254_00041	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A254_00043	ENOG4107GFK	fumarate
A254_00044	ENOG4105DX0	Hemolysin A
A254_00049	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A254_00051	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A254_00052	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A254_00055	ENOG4105Y3U	Transglycosylase-associated protein
A254_00056	ENOG4106UW1	Major Facilitator superfamily
A254_00062	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A254_00063	ENOG4105HHA	aminodeoxychorismate lyase
A254_00065	ENOG4105C7B	Threonine dehydratase
A254_00067	ENOG4105C26	Dehydrogenase
A254_00068	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
A254_00069	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A254_00074	ENOG4105CXK	mandelate racemase muconate lactonizing
A254_00076	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
A254_00077	ENOG4105GVF	(ABC) transporter
A254_00078	ENOG4107ZSV	Receptor
A254_00079	ENOG41060IM	Heme exporter protein
A254_00082	ENOG4105DA4	cytochrome c-type biogenesis protein
A254_00083	ENOG4107QX9	Thiol disulfide interChange protein
A254_00084	ENOG4105KWW	Biogenesis protein
A254_00099	ENOG4108RDB	capsule polysaccharide export inner-membrane protein
A254_00100	ENOG4108TJN	glycosyl transferase group 1
A254_00102	ENOG4108DMA	Nad-dependent epimerase dehydratase
A254_00103	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
A254_00105	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A254_00106	ENOG4105EUJ	GTP cyclohydrolase i
A254_00107	ENOG4107S8C	mandelate racemase muconate lactonizing
A254_00111	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A254_00116	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A254_00120	ENOG4105C1J	atp-dependent rna helicase
A254_00123	ENOG4105DC8	reductase
A254_00127	ENOG4105ES4	Nitrilase
A254_00131	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
A254_00135	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A254_00136	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A254_00137	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A254_00139	ENOG4105C79	DNA protecting protein DprA
A254_00141	ENOG4105D06	uba thif-type nad fad binding protein
A254_00143	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A254_00144	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A254_00150	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
A254_00151	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
A254_00157	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A254_00158	ENOG4105E0F	Histidine kinase
A254_00162	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
A254_00164	ENOG4105RD7	BadF BadG BcrA BcrD
A254_00167	ENOG41081UC	Inherit from COG: Competence protein
A254_00168	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A254_00170	ENOG4105BZU	Histidine kinase
A254_00172	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
A254_00180	ENOG4105KNE	Phosphatidate cytidylyltransferase
A254_00182	ENOG4105DZP	Membrane-associated zinc metalloprotease
A254_00183	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A254_00189	ENOG4105C3M	thioredoxin reductase
A254_00192	ENOG4105C7K	acetolactate synthase
A254_00195	ENOG4105CA0	peroxidase
A254_00196	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A254_00200	ENOG4108Z1B	Cyclase dehydrase
A254_00201	ENOG4105CEV	competence damage-inducible protein
A254_00205	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A254_00206	ENOG4105ES5	Histidine kinase
A254_00207	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A254_00210	ENOG4105WJX	transcriptional regulator MERR family
A254_00216	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A254_00217	ENOG4105CEP	NADH dehydrogenase
A254_00218	ENOG4107835	probably involved in intracellular septation (By similarity)
A254_00219	ENOG4105DJ2	Major Facilitator Superfamily
A254_00221	ENOG4105F7P	transcriptional regulator AsnC family
A254_00224	ENOG4105I8F	Histidine kinase
A254_00225	ENOG4108097	ATP-binding protein
A254_00226	ENOG4108S0S	Nucleotidyl transferase
A254_00228	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
A254_00229	ENOG4105K63	Thioredoxin
A254_00230	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A254_00231	ENOG4105DXN	mazG family
A254_00233	ENOG4105F8V	Hydrolase, tatD family
A254_00235	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A254_00236	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A254_00237	ENOG4105DZ1	carboxypeptidase
A254_00239	ENOG4105CVE	Lytic murein transglycosylase
A254_00240	ENOG4105K2Z	endo-1,4-d-glucanase (EC 3.2.1.4)
A254_00241	ENOG4105EJG	cellulose synthase
A254_00244	ENOG4107QZ7	Cellulose synthase catalytic subunit
A254_00251	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
A254_00253	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
A254_00254	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A254_00256	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A254_00258	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
A254_00262	ENOG41087YS	Phage shock protein A
A254_00264	ENOG4105E51	psp operon transcriptional activator
A254_00265	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A254_00268	ENOG4105DJ0	Poly(A) Polymerase
A254_00270	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A254_00273	ENOG4105E2Z	phosphate ABC transporter (Permease
A254_00274	ENOG4105C8U	phosphate abc transporter
A254_00275	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
A254_00279	ENOG4105HA9	of methanol dehydrogenase type
A254_00283	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A254_00287	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A254_00295	ENOG4105C3J	Cysteine desulfurase
A254_00296	ENOG4105DHZ	alpha beta
A254_00299	ENOG4105CY3	ABC transporter, permease
A254_00300	ENOG4105DHJ	ABC, transporter
A254_00307	ENOG4105M0C	cytoplasmic protein
A254_00309	ENOG4105CQB	FAD linked oxidase domain protein
A254_00310	ENOG4105FFC	UPF0187 protein
A254_00311	ENOG4105EEI	dihydropteroate synthase
A254_00312	ENOG4105CEC	DNA methylase N-4 N-6
A254_00314	ENOG4105DWF	phosphomethylpyrimidine kinase
A254_00316	ENOG4105DUX	Transporter
A254_00317	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
A254_00318	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A254_00319	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A254_00321	ENOG4105D64	Mechanosensitive ion channel
A254_00324	ENOG4108ZNX	Heat shock protein
A254_00327	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A254_00332	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
A254_00333	ENOG4108JQ5	ABC transporter
A254_00334	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A254_00335	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A254_00337	ENOG4108FN7	Aldo keto reductase
A254_00340	ENOG410901P	UPF0249 protein
A254_00345	ENOG4105C7N	Xanthine uracil vitamin C permease
A254_00347	ENOG4105D9N	nucleoside
A254_00348	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A254_00349	ENOG4105CW7	secretion protein, HlyD family
A254_00351	ENOG41064MX	Tetr family transcriptional regulator
A254_00352	ENOG4105CE4	GlcNAc 6-P deacetylase
A254_00354	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
A254_00357	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
A254_00358	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
A254_00359	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
A254_00363	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
A254_00368	ENOG4107R3K	hydrolase
A254_00371	ENOG41090HR	transcriptional regulator
A254_00372	ENOG4107QUY	Guanine deaminase
A254_00374	ENOG4105CGF	Aromatic amino acid aminotransferase
A254_00375	ENOG4107Y9U	Membrane
A254_00381	ENOG4105KXX	peptidase s58 dmpa
A254_00385	ENOG4105VEQ	Cold shock protein
A254_00391	ENOG4105BZU	Histidine kinase
A254_00398	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A254_00401	ENOG4105EY8	ABC transporter
A254_00403	ENOG4105ECX	polysaccharide export
A254_00405	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
A254_00406	ENOG4105DJ9	glucan biosynthesis protein
A254_00408	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A254_00409	ENOG4108KPZ	tonB-dependent Receptor
A254_00412	ENOG4105C4K	Nad synthetase
A254_00418	ENOG4105DVT	helicase
A254_00419	ENOG4105DK7	lysyl-tRNA synthetase
A254_00420	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A254_00421	ENOG4108C33	Resolvase
A254_00424	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A254_00425	ENOG4108UJD	30S ribosomal protein S9
A254_00426	ENOG4105C8Q	Methyl-accepting chemotaxis
A254_00427	ENOG4105CBS	Chea signal transduction histidine kinase
A254_00428	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A254_00435	ENOG4107S11	squalene-associated FAD-dependent desaturase
A254_00436	ENOG4105FE1	phytoene synthase
A254_00437	ENOG4105FBD	synthase
A254_00438	ENOG4107R8N	Glycosyl transferase, family 2
A254_00440	ENOG4105PGM	cation diffusion facilitator family transporter
A254_00442	ENOG4105KG3	cytidine deaminase
A254_00443	ENOG4105DHP	deoxycytidine triphosphate deaminase
A254_00444	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
A254_00445	ENOG4107QMP	dna polymerase iii subunits gamma and tau
A254_00446	ENOG4108ZIT	Ferredoxin, 2FE-2S
A254_00450	ENOG4105CTB	Polyprenyl synthetase
A254_00452	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A254_00455	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A254_00457	ENOG4105TW1	Carbohydrate-selective porin OprB
A254_00458	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
A254_00461	ENOG4105C75	arginyL-tRNA synthetase
A254_00465	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A254_00466	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A254_00481	ENOG4105C6T	cysteine synthase
A254_00483	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A254_00484	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A254_00491	ENOG410856B	UPF0235 protein
A254_00493	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A254_00495	ENOG4107SQ0	N-acetyl-gamma-glutamyl-phosphate reductase
A254_00498	ENOG4105CJ1	ABC, transporter
A254_00499	ENOG4105CMI	transporter
A254_00500	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A254_00501	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
A254_00506	ENOG4105CD3	dihydroorotase
A254_00514	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
A254_00517	ENOG410642W	LysR family Transcriptional regulator
A254_00518	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A254_00521	ENOG4105C5X	domain protein
A254_00522	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
A254_00524	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A254_00525	ENOG4105CJW	magnesium transporter
A254_00534	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A254_00539	ENOG4105VW4	glutaredoxin 3
A254_00550	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A254_00552	ENOG41061CK	Antibiotic biosynthesis monooxygenase
A254_00554	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A254_00555	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A254_00556	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A254_00557	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
A254_00565	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A254_00568	ENOG4105C9K	Endothelin-converting enzyme 1
A254_00571	ENOG4105E4C	Lytic transglycosylase catalytic
A254_00572	ENOG4108RRZ	Transcription elongation factor GreB
A254_00573	ENOG4105CSR	polyphosphate kinase 2
A254_00577	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
A254_00580	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
A254_00581	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A254_00585	ENOG4107RCI	amp-dependent synthetase and ligase
A254_00589	ENOG4105KPY	Small multidrug resistance protein
A254_00594	ENOG4108ZHJ	Organic hydroperoxide resistance protein
A254_00598	ENOG4107TT2	Auxin Efflux Carrier
A254_00599	ENOG4105C7K	acetolactate synthase
A254_00612	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
A254_00614	ENOG4108505	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A254_00615	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
A254_00618	ENOG4107PQ6	Inherit from NOG: atp synthase
A254_00622	ENOG4105W5Q	DNA repair protein (RadC
A254_00623	ENOG4105C83	adenylosuccinate lyase
A254_00627	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A254_00628	ENOG4105F4X	arginine
A254_00631	ENOG4108ZJ4	polysaccharide deacetylase
A254_00632	ENOG4105IPI	Membrane
A254_00635	ENOG4105D00	flagellar biosynthetic protein flhB
A254_00636	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
A254_00637	ENOG4105VS8	Flagellar biosynthetic protein fliq
A254_00638	ENOG4105CN7	Flagellar biosynthetic protein FliP
A254_00640	ENOG4105DD5	Flagellar motor switch protein
A254_00641	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A254_00645	ENOG4108JIR	Flagellum-specific ATP synthase
A254_00647	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A254_00648	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
A254_00649	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
A254_00650	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A254_00651	ENOG4105I03	Flagellin
A254_00654	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A254_00656	ENOG4105D7B	Flagellar biosynthesis protein flha
A254_00661	ENOG4105E14	MotA TolQ exbB proton channel
A254_00663	ENOG4108ZC9	flagellar basal-body rod protein flgc
A254_00664	ENOG4105W00	Flagellar hook capping protein
A254_00665	ENOG4105BZE	flagellar hook protein, FlgE
A254_00666	ENOG4108KPB	Flagellar basal-body rod protein FlgF
A254_00667	ENOG4105CGA	flagellar basal-body rod protein FlgG
A254_00673	ENOG4107RD7	Flagellar Motor Protein, MotA
A254_00674	ENOG4105ER2	Ompa motb domain protein
A254_00677	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A254_00684	ENOG4105E96	Colicin v production protein
A254_00687	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
A254_00689	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A254_00691	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
A254_00692	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
A254_00693	ENOG4105EYM	Major Facilitator superfamily
A254_00694	ENOG4105CK2	sodium dicarboxylate symporter
A254_00695	ENOG4105FE9	pseudouridine synthase
A254_00696	ENOG4106H78	methyltransferase
A254_00698	ENOG4105E9S	glutaredoxin 2
A254_00700	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A254_00702	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A254_00706	ENOG4105D94	Major Facilitator Superfamily
A254_00707	ENOG4105CQ7	ATP-dependent helicase
A254_00708	ENOG4105EAH	synthase
A254_00709	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
A254_00723	ENOG4107R4J	Chloride channel
A254_00724	ENOG4105CHH	sulfate transporter
A254_00726	ENOG4108HMX	isocitrate dehydrogenase (NADP)
A254_00727	ENOG4108I0Z	Aconitate hydratase
A254_00750	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
A254_00755	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
A254_00759	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
A254_00760	ENOG4105YVM	Phosphoesterase, PA-phosphatase related
A254_00767	ENOG4108YZN	class I peptide chain release factor
A254_00769	ENOG4105CKK	Glycosyl transferase, family 2
A254_00773	ENOG4108JQC	penicillin-binding protein 1A
A254_00775	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A254_00779	ENOG4105C5F	glutamine synthetase
A254_00780	ENOG4108YZA	Nitrogen regulatory protein pii
A254_00781	ENOG4105DC7	peptidase M24
A254_00787	ENOG4108M9J	MaoC like domain protein
A254_00788	ENOG4105C1G	acyl-Coa dehydrogenase
A254_00790	ENOG4105D6E	homoserine dehydrogenase
A254_00791	ENOG4105CBT	Fructose-1,6-bisphosphatase
A254_00793	ENOG4105BZU	Histidine kinase
A254_00797	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
A254_00802	ENOG4105HEI	LysR family (Transcriptional regulator
A254_00804	ENOG4105CRQ	synthase (Component I)
A254_00806	ENOG4105CP7	Triose-phosphate isomerase
A254_00809	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
A254_00810	ENOG4105D60	lipoprotein releasing system transmembrane protein
A254_00815	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A254_00821	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
A254_00824	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A254_00825	ENOG4107VXZ	Hydrolase
A254_00837	ENOG4108Z4V	iron-sulfur cluster assembly
A254_00838	ENOG4105VG1	fes assembly suf system protein
A254_00839	ENOG4105C9B	Cysteine desulfurase
A254_00840	ENOG4105JRK	feS assembly protein SufD
A254_00846	ENOG4105E9Q	Acyl-transferase
A254_00849	ENOG4105CAK	Cell division ATP-binding protein ftsE
A254_00852	ENOG41081FY	multiple antibiotic resistance (MarC)-related
A254_00853	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A254_00854	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A254_00855	ENOG4105DBV	ornithine carbamoyltransferase
A254_00856	ENOG4105C8Y	Acetylornithine aminotransferase
A254_00858	ENOG4105E3A	(ABC) transporter
A254_00861	ENOG4105C9X	ppx gppa phosphatase
A254_00888	ENOG4105EDQ	levansucrase EC 2.4.1.10
A254_00889	ENOG4105EDQ	levansucrase EC 2.4.1.10
A254_00892	ENOG4108UYU	AsnC family transcriptional regulator
A254_00902	ENOG4105CNI	cell division protein FtsW
A254_00905	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
A254_00907	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
A254_00913	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
A254_00914	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
A254_00915	ENOG4105BZU	Histidine kinase
A254_00917	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A254_00919	ENOG4105CHM	Aminotransferase
A254_00923	ENOG4107QMS	site-determining protein
A254_00924	ENOG4106HMZ	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A254_00926	ENOG4105ECY	inositol monophosphatase
A254_00928	ENOG4105C28	cystathionine
A254_00931	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A254_00933	ENOG4105DTN	riboflavin biosynthesis protein ribF
A254_00937	ENOG4108KEZ	Dehydrogenase
A254_00939	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A254_00941	ENOG4105CH2	amidohydrolase
A254_00943	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A254_00944	ENOG4105E12	capsule polysaccharide
A254_00953	ENOG4105EE5	Membrane protein terC
A254_00954	ENOG4108Z6B	deaminase
A254_00957	ENOG4107QNK	)-transporter
A254_00959	ENOG4106BRA	Membrane
A254_00961	ENOG4105MPN	Membrane
A254_00962	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A254_00963	ENOG4105BZS	acriflavin resistance protein
A254_00964	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A254_00970	ENOG4108IUZ	ABC transporter
A254_00971	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A254_00973	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A254_00983	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
A254_00985	ENOG4105IFJ	Histidine kinase
A254_00986	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
A254_00987	ENOG4105CXG	d-lactate dehydrogenase
A254_00993	ENOG4108UXN	response regulator
A254_00995	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A254_00997	ENOG4105K70	DNA-binding protein
A254_00999	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
A254_01005	ENOG4105C0H	protease
A254_01008	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A254_01010	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A254_01011	ENOG4105EHG	Permease protein
A254_01013	ENOG4105C2M	dna polymerase I
A254_01014	ENOG4105EMU	Dehydrogenase
A254_01016	ENOG4105DWV	Homoserine O-trans-acetylase
A254_01019	ENOG4108VJ1	Transcriptional regulator (CarD family
A254_01020	ENOG4108Z4U	Ferredoxin
A254_01021	ENOG4105CQR	helicase
A254_01022	ENOG4105DR5	peptidase
A254_01024	ENOG4107R73	Mate efflux family protein
A254_01033	ENOG4107SWG	transcriptional regulator MERR family
A254_01034	ENOG4105C8Q	Methyl-accepting chemotaxis
A254_01035	ENOG4105DDQ	anthranilate synthase
A254_01036	ENOG4108I0Q	anthranilate phosphoribosyltransferase
A254_01038	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A254_01039	ENOG4108JQC	penicillin-binding protein 1A
A254_01041	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
A254_01044	ENOG4105C03	ribonuclease
A254_01048	ENOG4105EJQ	L-serine dehydratase
A254_01051	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
A254_01054	ENOG4105C5H	ABC transporter
A254_01057	ENOG4105EIE	fructose-bisphosphate aldolase
A254_01060	ENOG4105CV1	Transketolase (EC 2.2.1.1)
A254_01066	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
A254_01067	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A254_01070	ENOG4108ZZF	transport protein (ExbD)
A254_01071	ENOG4105CWK	Biopolymer transport protein, ExbB
A254_01072	ENOG4107YD3	Thioesterase
A254_01074	ENOG4105C5I	Dehydrogenase
A254_01079	ENOG4105Y2X	UPF0335 protein
A254_01080	ENOG4105CA9	Pyruvate kinase
A254_01085	ENOG4108IYU	L-aspartate oxidase
A254_01086	ENOG4105DA5	(ABC) transporter
A254_01087	ENOG4105DFA	alanine racemase domain protein
A254_01088	ENOG4105KJF	protein tyrosine phosphatase
A254_01104	ENOG4108Z66	YbaK ebsC protein
A254_01107	ENOG4105D1H	recombination factor protein RarA
A254_01108	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
A254_01114	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
A254_01115	ENOG4105DDQ	anthranilate synthase
A254_01116	ENOG4105CRQ	synthase (Component I)
A254_01118	ENOG4105C5H	ABC transporter
A254_01121	ENOG410814C	multidrug resistance protein
A254_01125	ENOG4105FQP	Beta-lactamase
A254_01133	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
A254_01137	ENOG4105C8Q	Methyl-accepting chemotaxis
A254_01139	ENOG4105CBS	Chea signal transduction histidine kinase
A254_01140	ENOG4105BZU	Histidine kinase
A254_01141	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A254_01143	ENOG4108VYJ	response regulator receiver protein
A254_01144	ENOG4108V3W	Chemotaxis protein, CheW
A254_01146	ENOG4105C9A	Phoh family
A254_01148	ENOG4105C37	(CBS) domain
A254_01150	ENOG4105E9S	glutaredoxin 2
A254_01157	ENOG4105BZW	Glycerate kinase
A254_01160	ENOG4107TSN	permease
A254_01161	ENOG4108ZT1	Transcriptional regulator
A254_01163	ENOG4105DJ2	Major Facilitator Superfamily
A254_01169	ENOG4105E2X	shikimate dehydrogenase
A254_01171	ENOG4107RZZ	dna polymerase iii epsilon subunit
A254_01172	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
A254_01173	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A254_01176	ENOG4108ZZ3	UPF0260 protein
A254_01179	ENOG4106H3A	restriction
A254_01180	ENOG4105DC1	bifunctional purine biosynthesis protein purh
A254_01184	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A254_01185	ENOG4107QR9	Iron-sulfur cluster binding protein
A254_01188	ENOG4105DJV	ribulose-phosphate 3-epimerase
A254_01194	ENOG4105CSA	Coproporphyrinogen iii oxidase
A254_01202	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
A254_01203	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
A254_01204	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A254_01205	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A254_01206	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A254_01208	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A254_01209	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A254_01211	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A254_01213	ENOG4105D05	Receptor
A254_01214	ENOG4105CPC	Aldo Keto reductase
A254_01215	ENOG4108TY5	Exhibits lactonase activity. Acts in cells with perturbed membrane integrity and is possibly related to the membrane homeostasis
A254_01218	ENOG4107QJE	Chromosome Partitioning Protein
A254_01219	ENOG4105FA0	parb-like partition protein
A254_01220	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A254_01222	ENOG4105F84	Ornithine cyclodeaminase
A254_01223	ENOG4105CXD	Specific inhibitor of chromosomal initiation of replication in vitro. Binds the three 13-mers in the origin (oriC) to block initiation of replication (By similarity)
A254_01230	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
A254_01232	ENOG4105BZN	citrate synthase
A254_01233	ENOG4105BZU	Histidine kinase
A254_01238	ENOG4105BZF	Glycosyl transferase (Group 1
A254_01239	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A254_01240	ENOG4107R1I	NAD-dependent malic enzyme
A254_01243	ENOG4105D07	Signal peptide peptidase, SppA
A254_01244	ENOG4105CFP	Peptidase U32
A254_01246	ENOG4107T7U	Sulfatase
A254_01247	ENOG41084CK	capsule polysaccharide
A254_01248	ENOG4105C25	Primosomal protein n'
A254_01251	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A254_01252	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A254_01254	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
A254_01256	ENOG4105D7Z	glutathione synthase
A254_01257	ENOG4105C3G	gtp-binding protein
A254_01267	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A254_01270	ENOG41082R8	50S ribosomal protein l32
A254_01272	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A254_01275	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A254_01276	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A254_01279	ENOG4105D98	threonine synthase
A254_01283	ENOG4105D3W	isochorismatase
A254_01284	ENOG4108KK1	membrane protein AbrB duplication
A254_01285	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A254_01286	ENOG4105WPN	DNA integration recombination invertion protein
A254_01287	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
A254_01288	ENOG4108KK1	membrane protein AbrB duplication
A254_01291	ENOG4105D52	delta-aminolevulinic acid dehydratase
A254_01299	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A254_01300	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A254_01313	ENOG4105EA8	2-Nitropropane dioxygenase
A254_01325	ENOG41089BK	Glutamine amido-transferase
A254_01327	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
A254_01332	ENOG4105EHG	Permease protein
A254_01333	ENOG4105E0A	ABC, transporter
A254_01334	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
A254_01335	ENOG4105D9R	oxidoreductase
A254_01339	ENOG4105X1Q	TOBE domain protein
A254_01340	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A254_01342	ENOG4107S73	homocitrate synthase
A254_01343	ENOG4105C3J	Cysteine desulfurase
A254_01345	ENOG4105QAS	Iron-sulfur cluster assembly accessory protein
A254_01346	ENOG4105PS4	nifq family
A254_01347	ENOG4105WCA	Ferredoxin
A254_01348	ENOG4108VQE	nitrogen fixation protein
A254_01350	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
A254_01355	ENOG4105E0K	tonB-dependent siderophore receptor
A254_01358	ENOG4105XV5	nifz family
A254_01361	ENOG4107WT5	transcriptional regulator (NifA
A254_01363	ENOG4105DGN	Electron transport complex
A254_01364	ENOG4108R3D	Electron transport complex
A254_01365	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
A254_01366	ENOG4105D6A	Electron transport complex
A254_01367	ENOG4108UQQ	Electron transport complex
A254_01368	ENOG4108E8M	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
A254_01369	ENOG4105VDB	UPF0125 protein
A254_01371	ENOG4108UW5	maltose o-acetyltransferase
A254_01372	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A254_01373	ENOG4105CUB	amino acid
A254_01374	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A254_01375	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A254_01376	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A254_01377	ENOG4105CAT	Cytidine monophosphate kinase
A254_01381	ENOG4106NZI	LysR family Transcriptional regulator
A254_01384	ENOG4105BZ1	(ABC) transporter
A254_01388	ENOG4105D64	Mechanosensitive ion channel
A254_01396	ENOG4105CV8	reductase
A254_01397	ENOG4105CPQ	Dehydrogenase
A254_01398	ENOG4108I6A	alcohol dehydrogenase
A254_01403	ENOG4107RX3	Mg2 transporter protein cora family protein
A254_01404	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
A254_01406	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
A254_01408	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A254_01409	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
A254_01412	ENOG4105C26	Dehydrogenase
A254_01413	ENOG4105DP0	ferredoxin-NADP reductase
A254_01417	ENOG410903C	(LipO)protein
A254_01419	ENOG4105SYT	Methylenetetrahydrofolate reductase
A254_01420	ENOG4105C3R	Methionine synthase
A254_01421	ENOG4105C3R	Methionine synthase
A254_01425	ENOG4108HRK	Histidine kinase
A254_01426	ENOG4108VAC	response regulator
A254_01429	ENOG4105C5Q	Transcriptional regulator
A254_01431	ENOG4105D7W	serine acetyltransferase
A254_01434	ENOG4105CHM	Aminotransferase
A254_01439	ENOG4107QPD	alcohol dehydrogenase
A254_01449	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A254_01451	ENOG4105C3F	Signal peptidase i
A254_01454	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A254_01456	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A254_01458	ENOG4105CNU	cell division protein FtsK
A254_01459	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
A254_01461	ENOG4105CGK	Exodeoxyribonuclease III
A254_01462	ENOG4107QJN	gtp cyclohydrolase ii
A254_01463	ENOG4105KVH	Transcriptional regulator
A254_01468	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A254_01469	ENOG4107U9T	Pfam:Ribonuclease_BN
A254_01470	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A254_01471	ENOG4105CD3	dihydroorotase
A254_01472	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
A254_01474	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
A254_01477	ENOG4105HDK	L-asparaginase
A254_01478	ENOG4105CEB	Aspartate aminotransferase
A254_01482	ENOG4105CQC	Prephenate dehydratase
A254_01483	ENOG4105CEN	a g-specific adenine glycosylase
A254_01486	ENOG4105CV8	reductase
A254_01493	ENOG4105CN1	protease
A254_01497	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
A254_01505	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A254_01506	ENOG4105CFH	Aspartokinase
A254_01508	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
A254_01509	ENOG4107S1E	Beta-lactamase
A254_01511	ENOG4105E50	uracil-dna glycosylase
A254_01514	ENOG4108JA2	transcriptioN-repair coupling factor
A254_01515	ENOG4105CB5	ATP-dependent DNA helicase recG
A254_01520	ENOG4105C31	Tryptophanyl-tRNA synthetase
A254_01521	ENOG4105CJR	Integral membrane protein (MviN
A254_01525	ENOG4105CA3	membrane-bound lytic murein transglycosylase
A254_01529	ENOG4105E0K	tonB-dependent siderophore receptor
A254_01535	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
A254_01536	ENOG4105C0P	Mg chelatase subunit ChlI
A254_01537	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A254_01538	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A254_01554	ENOG4107S76	domain protein
A254_01562	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A254_01563	ENOG4105CY3	ABC transporter, permease
A254_01564	ENOG4105DHJ	ABC, transporter
A254_01565	ENOG4108Z7R	Chaperone CsaA
A254_01566	ENOG4105EJ9	Membrane
A254_01569	ENOG4108UQY	Iron-storage protein
A254_01570	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A254_01571	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A254_01580	ENOG4105ENX	hydrolase
A254_01581	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
A254_01582	ENOG4107RTG	Major Facilitator superfamily
A254_01583	ENOG4105EMU	Dehydrogenase
A254_01584	ENOG4105EQ2	LysR family Transcriptional regulator
A254_01587	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A254_01588	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A254_01590	ENOG4105F1A	Pyruvate formate-lyase
A254_01598	ENOG4105PDP	Short chain dehydrogenase
A254_01599	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A254_01602	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A254_01607	ENOG4105EWU	Squalene--hopene cyclase
A254_01612	ENOG4108UUM	single-stranded DNA-binding protein
A254_01613	ENOG4105CE1	Ferrous iron transport protein b
A254_01615	ENOG4105C0B	DNA polymerase III (alpha subunit)
A254_01618	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
A254_01619	ENOG4105C2X	Arabinose 5-phosphate isomerase
A254_01623	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A254_01634	ENOG4108JJ7	ABC transporter
A254_01636	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A254_01638	ENOG4105CUT	histidyl-tRNA synthetase
A254_01639	ENOG4105F0N	pyrophosphate phospho-hydrolase
A254_01647	ENOG4105K59	histidine triad (HIT) protein
A254_01648	ENOG4105CUB	amino acid
A254_01649	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
A254_01650	ENOG4108WBT	adenosyltransferase
A254_01655	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
A254_01656	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
A254_01657	ENOG4108KMM	Diguanylate cyclase
A254_01660	ENOG4105C4R	Atp-dependent dna helicase
A254_01663	ENOG4105BZJ	Electron transfer flavoprotein
A254_01664	ENOG4105C10	Electron transfer flavoprotein
A254_01665	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
A254_01667	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A254_01672	ENOG4105C44	Serine transporter
A254_01677	ENOG4108C33	Resolvase
A254_01678	ENOG4105F27	Major Facilitator
A254_01680	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
A254_01681	ENOG4105DEI	Mannitol dehydrogenase
A254_01687	ENOG4108S55	polysaccharide biosynthesis protein
A254_01689	ENOG4105FC8	fad dependent oxidoreductase
A254_01691	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
A254_01692	ENOG4105EW9	transcriptional regulator AsnC family
A254_01694	ENOG4105TXM	Domain of unknown function (DUF3576)
A254_01702	ENOG4105CBD	Diacylglycerol kinase
A254_01703	ENOG4105W5Q	DNA repair protein (RadC
A254_01704	ENOG4108UB3	Thiamine monophosphate
A254_01708	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
A254_01709	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
A254_01710	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
A254_01711	ENOG4105C1J	atp-dependent rna helicase
A254_01714	ENOG41072GX	Peptidase M22 Glycoprotease
A254_01716	ENOG4108YXV	Transcriptional regulator
A254_01717	ENOG41090R7	Ferric uptake
A254_01718	ENOG4108UQY	Iron-storage protein
A254_01721	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A254_01723	ENOG41074H6	response regulator
A254_01725	ENOG4105DR5	peptidase
A254_01726	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A254_01727	ENOG4105CGK	Exodeoxyribonuclease III
A254_01739	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A254_01740	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
A254_01743	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A254_01757	ENOG4106TD9	Diguanylate cyclase
A254_01758	ENOG4105D4P	Coproporphyrinogen iii oxidase
A254_01764	ENOG4105KVH	Transcriptional regulator
A254_01772	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
A254_01775	ENOG4105C26	Dehydrogenase
A254_01779	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
A254_01781	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
A254_01782	ENOG4105D2N	Aldolase
A254_01783	ENOG4108MGF	sugar kinase
A254_01784	ENOG4107SCQ	Iron-containing alcohol dehydrogenase
A254_01787	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A254_01791	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A254_01801	ENOG4105VXN	addiction module toxin, RelE StbE family
A254_01802	ENOG4107QJE	Chromosome Partitioning Protein
A254_01823	ENOG4105Y2X	UPF0335 protein
A254_01834	ENOG4105VXN	addiction module toxin, RelE StbE family
A254_01865	ENOG4105ED4	portal protein
A254_01867	ENOG4107QJE	Chromosome Partitioning Protein
A254_01887	ENOG4105BZ1	(ABC) transporter
A254_01888	ENOG4105BZ1	(ABC) transporter
A254_01893	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
A254_01897	ENOG41086VY	Fic/DOC family
A254_01912	ENOG4105QUW	
A254_01914	ENOG410802X	bacteriophage n4 adsorption protein b
A254_01915	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A254_01916	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A254_10004	ENOG41082FP	UPF0102 protein