locus-tag	class	description
ZMO0002	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ZMO0005	COG0175	sulfate reduction
ZMO0006	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ZMO0006	COG1648	precorrin-2 dehydrogenase activity
ZMO0007	COG0175	sulfate reduction
ZMO0008	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ZMO0009	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ZMO0012	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ZMO0013	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ZMO0014	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ZMO0015	COG1420	regulation of RNA biosynthetic process
ZMO0016	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ZMO0018	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ZMO0021	COG1139	Iron-sulfur cluster binding protein
ZMO0022	COG0247	lactate metabolic process
ZMO0027	COG0138	bifunctional purine biosynthesis protein purh
ZMO0028	COG1715	Restriction endonuclease
ZMO0033	COG2983	Belongs to the UPF0260 family
ZMO0037	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ZMO0038	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ZMO0039	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ZMO0040	COG0237	dephospho-CoA kinase activity
ZMO0043	COG0424	maF-like protein
ZMO0052	COG2807	transmembrane transport
ZMO0053	COG0596	Alpha beta hydrolase
ZMO0054	COG1846	Transcriptional regulator
ZMO0055	COG0730	response to heat
ZMO0056	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ZMO0059	COG1929	Belongs to the glycerate kinase type-1 family
ZMO0070	COG2999	glutathione oxidoreductase activity
ZMO0074	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ZMO0075	COG1702	phosphate starvation-inducible protein PhoH
ZMO0077	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ZMO0078	COG0835	chemotaxis
ZMO0080	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ZMO0081	COG2201	protein-glutamate methylesterase activity
ZMO0082	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ZMO0083	COG0643	Histidine kinase
ZMO0083	COG2198	Histidine kinase
ZMO0085	COG0840	transmembrane signaling receptor activity
ZMO0090	COG1028	Short-chain dehydrogenase reductase Sdr
ZMO0094	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ZMO0096	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ZMO0103	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ZMO0105	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ZMO0106	COG0066	3-isopropylmalate dehydratase activity
ZMO0113	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ZMO0114	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ZMO0114	COG0512	Glutamine amidotransferase of anthranilate synthase
ZMO0115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ZMO0116	COG1959	2 iron, 2 sulfur cluster binding
ZMO0117	COG1151	hydroxylamine reductase activity
ZMO0119	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ZMO0121	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ZMO0125	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ZMO0130	COG0671	phosphoesterase, PA-phosphatase related
ZMO0140	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ZMO0143	COG1131	(ABC) transporter
ZMO0149	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ZMO0152	COG0469	pyruvate kinase activity
ZMO0153	COG0217	transcriptional regulatory protein
ZMO0154	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ZMO0155	COG0632	four-way junction helicase activity
ZMO0157	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ZMO0158	COG2255	four-way junction helicase activity
ZMO0160	COG0824	Thioesterase
ZMO0161	COG0811	peptide transport
ZMO0162	COG0848	biopolymer transport protein
ZMO0165	COG0823	Involved in the tonB-independent uptake of proteins
ZMO0166	COG2885	chlorophyll binding
ZMO0169	COG1028	Short-chain dehydrogenase reductase Sdr
ZMO0170	COG0584	glycerophosphoryl diester phosphodiesterase
ZMO0172	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ZMO0177	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ZMO0178	COG0126	phosphoglycerate kinase activity
ZMO0179	COG1830	Aldolase
ZMO0180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ZMO0182	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ZMO0183	COG0488	(ABC) transporter
ZMO0186	COG0215	cysteine-tRNA ligase activity
ZMO0187	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ZMO0189	COG1760	l-serine dehydratase
ZMO0193	COG1530	ribonuclease E activity
ZMO0197	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ZMO0199	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ZMO0200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ZMO0202	COG0840	transmembrane signaling receptor activity
ZMO0203	COG0789	Transcriptional regulator
ZMO0206	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ZMO0207	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ZMO0209	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ZMO0211	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ZMO0214	COG0534	Mate efflux family protein
ZMO0216	COG0739	heme binding
ZMO0219	COG4581	dead DEAH box helicase
ZMO0220	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ZMO0221	COG1329	Transcriptional regulator
ZMO0224	COG2813	Specifically methylates the guanine in position
ZMO0224	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ZMO0225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ZMO0226	COG4221	oxidoreductase activity
ZMO0227	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ZMO0227	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ZMO0229	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ZMO0230	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ZMO0232	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ZMO0234	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ZMO0236	COG0489	protein tyrosine kinase activity
ZMO0238	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ZMO0239	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ZMO0240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ZMO0241	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ZMO0242	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ZMO0244	COG0776	regulation of translation
ZMO0246	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ZMO0247	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ZMO0249	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ZMO0255	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ZMO0256	COG0277	FAD linked oxidase domain protein
ZMO0257	COG0745	RESPONSE REGULATOR receiver
ZMO0258	COG2205	protein histidine kinase activity
ZMO0260	COG4133	protoheme IX ABC transporter activity
ZMO0262	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ZMO0271	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ZMO0273	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ZMO0274	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ZMO0275	COG1137	ATPase activity
ZMO0279	COG1278	Cold shock
ZMO0282	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ZMO0285	COG1538	Outer membrane efflux protein
ZMO0290	COG2733	membrane
ZMO0291	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ZMO0293	COG2814	Major facilitator Superfamily
ZMO0294	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ZMO0296	COG0590	tRNA wobble adenosine to inosine editing
ZMO0297	COG1253	flavin adenine dinucleotide binding
ZMO0299	COG0151	Belongs to the GarS family
ZMO0300	COG1570	exodeoxyribonuclease VII activity
ZMO0303	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ZMO0309	COG1028	Short-chain dehydrogenase reductase Sdr
ZMO0314	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ZMO0318	COG1028	Short-chain dehydrogenase reductase Sdr
ZMO0322	COG0196	riboflavin kinase activity
ZMO0323	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ZMO0324	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ZMO0326	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ZMO0327	COG0626	cystathionine gamma-synthase activity
ZMO0328	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ZMO0329	COG0483	inositol monophosphate 1-phosphatase activity
ZMO0331	COG3108	Peptidase M15
ZMO0332	COG0352	thiamine-phosphate diphosphorylase activity
ZMO0335	COG2894	cell division
ZMO0344	COG0312	modulator of DNA gyrase
ZMO0346	COG0004	ammonium transporteR
ZMO0347	COG1923	regulation of RNA biosynthetic process
ZMO0348	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ZMO0349	COG1678	Uncharacterized ACR, COG1678
ZMO0354	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ZMO0356	COG1792	Involved in formation and maintenance of cell shape
ZMO0360	COG0772	Belongs to the SEDS family
ZMO0362	COG0556	nucleotide-excision repair
ZMO0363	COG0343	queuine tRNA-ribosyltransferase activity
ZMO0364	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ZMO0366	COG0477	Major facilitator Superfamily
ZMO0367	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ZMO0368	COG0129	dihydroxy-acid dehydratase activity
ZMO0369	COG0837	glucose binding
ZMO0371	COG1794	racemase activity, acting on amino acids and derivatives
ZMO0372	COG1522	sequence-specific DNA binding
ZMO0374	COG1621	beta-fructofuranosidase activity
ZMO0375	COG1621	beta-fructofuranosidase activity
ZMO0401	COG5001	Diguanylate cyclase
ZMO0402	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ZMO0403	COG0248	Ppx GppA phosphatase
ZMO0406	COG0842	Transport permease protein
ZMO0408	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ZMO0409	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ZMO0410	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ZMO0411	COG0187	DNA topoisomerase II activity
ZMO0412	COG2095	MarC family integral membrane protein
ZMO0416	COG2884	Cell division ATP-binding protein ftsE
ZMO0420	COG0287	Prephenate dehydrogenase
ZMO0421	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ZMO0423	COG0719	Fe-S assembly protein
ZMO0425	COG0396	ATPase activity
ZMO0426	COG0719	Fe-S assembly protein
ZMO0427	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ZMO0428	COG2151	metal-sulfur cluster biosynthetic enzyme
ZMO0429	COG0316	Belongs to the HesB IscA family
ZMO0431	COG2171	N-acyltransferase activity
ZMO0433	COG0194	GDP metabolic process
ZMO0442	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ZMO0443	COG1372	Participates in initiation and elongation during chromosome replication
ZMO0443	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ZMO0446	COG1696	Membrane protein involved in D-alanine export
ZMO0453	COG1160	GTP binding
ZMO0454	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ZMO0457	COG1522	sequence-specific DNA binding
ZMO0458	COG1136	(ABC) transporter
ZMO0460	COG0442	prolyl-tRNA aminoacylation
ZMO0462	COG0504	CTP synthase activity
ZMO0465	COG0149	triose-phosphate isomerase activity
ZMO0468	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ZMO0471	COG0583	DNA-binding transcription factor activity
ZMO0473	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ZMO0476	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ZMO0476	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ZMO0480	COG5002	protein histidine kinase activity
ZMO0482	COG1494	fructose-1,6-bisphosphatase
ZMO0485	COG1960	acyl-CoA dehydrogenase activity
ZMO0486	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ZMO0491	COG0006	proline dipeptidase activity
ZMO0492	COG0347	Belongs to the P(II) protein family
ZMO0493	COG0174	glutamine synthetase
ZMO0497	COG0546	phosphoglycolate phosphatase activity
ZMO0498	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ZMO0499	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ZMO0503	COG0463	Glycosyl transferase, family 2
ZMO0505	COG0564	pseudouridine synthase activity
ZMO0507	COG1956	GAF domain-containing protein
ZMO0510	COG0508	dehydrogenase complex catalyzes the overall conversion of
ZMO0511	COG1607	acyl-coa hydrolase
ZMO0512	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ZMO0513	COG0671	phosphoesterase, PA-phosphatase related
ZMO0514	COG0049	tRNA binding
ZMO0515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ZMO0516	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ZMO0517	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ZMO0518	COG0088	Forms part of the polypeptide exit tunnel
ZMO0519	COG0089	rRNA binding
ZMO0520	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ZMO0521	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ZMO0522	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ZMO0523	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ZMO0524	COG0255	Belongs to the universal ribosomal protein uL29 family
ZMO0525	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ZMO0526	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ZMO0527	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ZMO0528	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ZMO0529	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ZMO0530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ZMO0531	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ZMO0532	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ZMO0533	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ZMO0534	COG1841	ribosomal large subunit assembly
ZMO0536	COG0200	Binds to the 23S rRNA
ZMO0537	COG0201	protein transport
ZMO0538	COG0563	adenylate kinase activity
ZMO0539	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ZMO0540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ZMO0541	COG0202	RNA polymerase activity
ZMO0542	COG0203	ribosomal protein L17
ZMO0543	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ZMO0544	COG0538	isocitrate dehydrogenase activity
ZMO0545	COG0134	indole-3-glycerol-phosphate synthase activity
ZMO0546	COG0659	secondary active sulfate transmembrane transporter activity
ZMO0547	COG0038	chloride channel
ZMO0549	COG1185	polyribonucleotide nucleotidyltransferase activity
ZMO0550	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ZMO0551	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ZMO0552	COG1435	thymidine kinase activity
ZMO0553	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ZMO0554	COG3064	Membrane
ZMO0554	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ZMO0557	COG0779	Required for maturation of 30S ribosomal subunits
ZMO0558	COG2133	pyrroloquinoline quinone binding
ZMO0560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ZMO0561	COG4771	TonB-dependent receptor
ZMO0562	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ZMO0563	COG0287	Prephenate dehydrogenase
ZMO0563	COG1605	Chorismate mutase
ZMO0564	COG0142	geranyltranstransferase activity
ZMO0565	COG1643	Atp-dependent helicase
ZMO0566	COG2814	Major facilitator Superfamily
ZMO0570	COG2264	protein methyltransferase activity
ZMO0571	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ZMO0572	COG1116	anion transmembrane transporter activity
ZMO0573	COG2999	glutathione oxidoreductase activity
ZMO0575	COG0742	ribosomal rna small subunit methyltransferase
ZMO0576	COG1187	pseudouridine synthase activity
ZMO0578	COG1301	dicarboxylic acid transport
ZMO0581	COG2223	nitrite transmembrane transporter activity
ZMO0582	COG0285	dihydrofolate synthase activity
ZMO0583	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ZMO0584	COG0159	tryptophan synthase activity
ZMO0585	COG0133	tryptophan synthase activity
ZMO0586	COG0135	phosphoribosylanthranilate isomerase activity
ZMO0587	COG0284	orotidine-5'-phosphate decarboxylase activity
ZMO0590	COG1286	toxin biosynthetic process
ZMO0593	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ZMO0594	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ZMO0598	COG4974	Belongs to the 'phage' integrase family
ZMO0599	COG0825	malonyl-CoA metabolic process
ZMO0607	COG1706	bacterial-type flagellum-dependent cell motility
ZMO0608	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ZMO0609	COG4786	Flagellar basal body rod
ZMO0611	COG1749	Flagellar hook protein flgE
ZMO0612	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ZMO0613	COG1558	bacterial-type flagellum-dependent cell motility
ZMO0616	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ZMO0625	COG0455	bacterial-type flagellum organization
ZMO0632	COG1677	Flagellar hook-basal body complex protein FliE
ZMO0635	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ZMO0643	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ZMO0648	COG1987	bacterial-type flagellum assembly
ZMO0649	COG1684	flagellar biosynthetic protein fliR
ZMO0650	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ZMO0653	COG0628	permease
ZMO0654	COG0726	polysaccharide deacetylase
ZMO0657	COG3138	arginine N-succinyltransferase
ZMO0660	COG0443	Heat shock 70 kDa protein
ZMO0661	COG0484	heat shock protein binding
ZMO0662	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ZMO0663	COG2003	Belongs to the UPF0758 family
ZMO0667	COG0356	it plays a direct role in the translocation of protons across the membrane
ZMO0669	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ZMO0671	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ZMO0672	COG0322	excinuclease ABC activity
ZMO0673	COG1381	Involved in DNA repair and RecF pathway recombination
ZMO0675	COG0583	DNA-binding transcription factor activity
ZMO0677	COG0473	3-isopropylmalate dehydrogenase activity
ZMO0688	COG0679	Auxin Efflux Carrier
ZMO0689	COG0673	inositol 2-dehydrogenase activity
ZMO0691	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ZMO0692	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ZMO0693	COG1764	response to oxidative stress
ZMO0697	COG2076	Multidrug Resistance protein
ZMO0704	COG0318	PFAM AMP-dependent synthetase and ligase
ZMO0707	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ZMO0708	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ZMO0709	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ZMO0712	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ZMO0713	COG0248	Ppx GppA phosphatase
ZMO0714	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ZMO0715	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ZMO0716	COG2326	polyphosphate kinase activity
ZMO0719	COG0741	lytic transglycosylase activity
ZMO0720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ZMO0721	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ZMO0722	COG3590	peptidase
ZMO0725	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ZMO0726	COG0081	regulation of translation
ZMO0727	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ZMO0728	COG0222	ribosome binding
ZMO0731	COG0085	RNA polymerase activity
ZMO0732	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ZMO0735	COG0439	Biotin carboxylase
ZMO0736	COG0511	ligase activity, forming carbon-carbon bonds
ZMO0737	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ZMO0738	COG2022	thiamine diphosphate biosynthetic process
ZMO0739	COG2329	Antibiotic biosynthesis monooxygenase
ZMO0743	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ZMO0749	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ZMO0750	COG0564	pseudouridine synthase activity
ZMO0753	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
ZMO0759	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ZMO0765	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ZMO0766	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ZMO0769	COG0482	sulfurtransferase activity
ZMO0770	COG2239	Acts as a magnesium transporter
ZMO0773	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ZMO0777	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ZMO0780	COG1538	Outer membrane efflux protein
ZMO0781	COG0583	DNA-binding transcription factor activity
ZMO0782	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ZMO0783	COG0154	amidase activity
ZMO0784	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ZMO0785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ZMO0791	COG0540	Belongs to the ATCase OTCase family
ZMO0792	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ZMO0794	COG1505	serine-type exopeptidase activity
ZMO0797	COG1028	Short-chain dehydrogenase reductase Sdr
ZMO0799	COG0842	Transport permease protein
ZMO0800	COG1129	ABC transporter
ZMO0800	COG0842	Transport permease protein
ZMO0804	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ZMO0806	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ZMO0807	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ZMO0809	COG1872	DUF167
ZMO0810	COG0101	tRNA pseudouridine synthase activity
ZMO0811	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ZMO0812	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ZMO0813	COG0242	peptide deformylase activity
ZMO0814	COG1322	Protein conserved in bacteria
ZMO0818	COG0720	synthase
ZMO0819	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ZMO0820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ZMO0823	COG0275	rRNA processing
ZMO0826	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ZMO0828	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ZMO0829	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ZMO0831	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ZMO0832	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ZMO0833	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ZMO0834	COG1181	Belongs to the D-alanine--D-alanine ligase family
ZMO0835	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ZMO0836	COG0849	cell division
ZMO0837	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ZMO0841	COG0038	chloride channel
ZMO0842	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ZMO0843	COG0018	arginyl-trna synthetase
ZMO0845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ZMO0850	COG2204	response regulator
ZMO0851	COG0259	pyridoxamine-phosphate oxidase activity
ZMO0852	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ZMO0853	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ZMO0854	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ZMO0855	COG0142	geranyltranstransferase activity
ZMO0856	COG1722	exodeoxyribonuclease VII activity
ZMO0859	COG1104	cysteine desulfurase activity
ZMO0861	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ZMO0862	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ZMO0863	COG0717	Belongs to the dCTP deaminase family
ZMO0864	COG0295	cytidine deaminase activity
ZMO0865	COG0305	Participates in initiation and elongation during chromosome replication
ZMO0867	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ZMO0868	COG1215	transferase activity, transferring glycosyl groups
ZMO0869	COG1562	ergosterol biosynthetic process
ZMO0870	COG1562	ergosterol biosynthetic process
ZMO0871	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ZMO0872	COG1657	PFAM Prenyltransferase squalene oxidase
ZMO0875	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ZMO0878	COG2201	protein-glutamate methylesterase activity
ZMO0880	COG0643	Histidine kinase
ZMO0880	COG2198	Histidine kinase
ZMO0882	COG0840	transmembrane signaling receptor activity
ZMO0883	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ZMO0884	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ZMO0890	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ZMO0892	COG1199	ATP-dependent helicase activity
ZMO0892	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ZMO0900	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ZMO0900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ZMO0903	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ZMO0905	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
ZMO0907	COG2943	transferase activity, transferring hexosyl groups
ZMO0913	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ZMO0914	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ZMO0915	COG2217	Heavy metal translocating P-type atpase
ZMO0919	COG0745	RESPONSE REGULATOR receiver
ZMO0919	COG3706	GGDEF domain
ZMO0923	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ZMO0924	COG0653	protein targeting
ZMO0925	COG1278	Cold shock
ZMO0927	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ZMO0928	COG3191	aminopeptidase activity
ZMO0936	COG0697	spore germination
ZMO0937	COG1448	Aminotransferase
ZMO0938	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
ZMO0939	COG0402	S-adenosylhomocysteine deaminase activity
ZMO0940	COG1846	Transcriptional regulator
ZMO0942	COG1621	beta-fructofuranosidase activity
ZMO0946	COG0544	peptidyl-prolyl cis-trans isomerase activity
ZMO0948	COG0740	serine-type endopeptidase activity
ZMO0949	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ZMO0951	COG0408	coproporphyrinogen oxidase activity
ZMO0952	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ZMO0956	COG0723	plastoquinol--plastocyanin reductase activity
ZMO0957	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ZMO0958	COG2857	Cytochrome c1
ZMO0959	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ZMO0962	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ZMO0965	COG1566	PFAM secretion protein HlyD family protein
ZMO0966	COG2814	Major facilitator Superfamily
ZMO0967	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ZMO0969	COG2252	PERMEase
ZMO0971	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ZMO0974	COG3394	polysaccharide catabolic process
ZMO0976	COG0667	Aldo Keto reductase
ZMO0979	COG4206	TonB-dependent receptor
ZMO0980	COG0592	DNA-directed DNA polymerase activity
ZMO0981	COG4172	Belongs to the ABC transporter superfamily
ZMO0985	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ZMO0986	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ZMO0987	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ZMO0989	COG0071	Belongs to the small heat shock protein (HSP20) family
ZMO0996	COG0668	transmembrane transport
ZMO0997	COG0800	Aldolase
ZMO0998	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ZMO0999	COG0009	L-threonylcarbamoyladenylate synthase
ZMO1000	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
ZMO1001	COG3104	oligopeptide transport
ZMO1002	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ZMO1003	COG0351	phosphomethylpyrimidine kinase
ZMO1003	COG0352	thiamine-phosphate diphosphorylase activity
ZMO1004	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ZMO1006	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ZMO1007	COG3781	membrane
ZMO1008	COG0277	FAD linked oxidase domain protein
ZMO1011	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ZMO1013	COG0424	maF-like protein
ZMO1014	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ZMO1017	COG1127	ABC transporter
ZMO1018	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ZMO1020	COG0019	diaminopimelate decarboxylase activity
ZMO1021	COG2945	thiolester hydrolase activity
ZMO1022	COG1104	cysteine desulfurase activity
ZMO1023	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ZMO1032	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ZMO1033	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ZMO1036	COG0137	argininosuccinate synthase activity
ZMO1039	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ZMO1039	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ZMO1042	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
ZMO1044	COG1970	mechanosensitive ion channel activity
ZMO1047	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ZMO1048	COG0573	inorganic phosphate transmembrane transporter activity
ZMO1049	COG0581	inorganic phosphate transmembrane transporter activity
ZMO1050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ZMO1052	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ZMO1054	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ZMO1055	COG5001	Diguanylate cyclase
ZMO1056	COG0617	tRNA 3'-terminal CCA addition
ZMO1060	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ZMO1061	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
ZMO1063	COG1842	Phage shock protein A
ZMO1069	COG0484	heat shock protein binding
ZMO1070	COG0552	protein localization to endoplasmic reticulum
ZMO1071	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ZMO1072	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ZMO1075	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ZMO1076	COG0228	four-way junction DNA binding
ZMO1077	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ZMO1078	COG0336	Belongs to the RNA methyltransferase TrmD family
ZMO1079	COG0335	large ribosomal subunit rRNA binding
ZMO1084	COG1215	transferase activity, transferring glycosyl groups
ZMO1085	COG0457	Tetratricopeptide repeat
ZMO1086	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
ZMO1087	COG2951	lytic endotransglycosylase activity
ZMO1089	COG1686	Belongs to the peptidase S11 family
ZMO1090	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ZMO1091	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ZMO1093	COG0084	hydrolase, TatD family'
ZMO1095	COG3956	TIGRFAM MazG family protein
ZMO1096	COG0557	exoribonuclease II activity
ZMO1098	COG1074	ATP-dependent DNA helicase activity
ZMO1100	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ZMO1101	COG0802	atpase or kinase
ZMO1102	COG2205	protein histidine kinase activity
ZMO1107	COG1522	sequence-specific DNA binding
ZMO1111	COG2807	transmembrane transport
ZMO1112	COG2917	probably involved in intracellular septation
ZMO1113	COG1252	NADH dehydrogenase
ZMO1114	COG1573	uracil-dna glycosylase
ZMO1115	COG1968	undecaprenyl-diphosphatase activity
ZMO1122	COG0776	regulation of translation
ZMO1124	COG2204	response regulator
ZMO1125	COG5000	phosphorelay sensor kinase activity
ZMO1126	COG2204	response regulator
ZMO1128	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ZMO1128	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ZMO1130	COG1546	Belongs to the CinA family
ZMO1130	COG1058	Belongs to the CinA family
ZMO1131	COG2867	negative regulation of translational initiation
ZMO1132	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ZMO1133	COG0288	reversible hydration of carbon dioxide
ZMO1135	COG0312	modulator of DNA gyrase
ZMO1136	COG1858	cytochrome C peroxidase
ZMO1138	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ZMO1139	COG0028	Belongs to the TPP enzyme family
ZMO1140	COG0440	acetolactate synthase activity
ZMO1141	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ZMO1142	COG0492	ferredoxin-NADP+ reductase activity
ZMO1145	COG0254	rRNA binding
ZMO1146	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ZMO1148	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ZMO1149	COG0750	zinc metalloprotease
ZMO1150	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ZMO1151	COG0575	Belongs to the CDS family
ZMO1152	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ZMO1153	COG0233	cytoplasmic translational termination
ZMO1154	COG0528	UMP kinase activity
ZMO1155	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ZMO1156	COG0052	Belongs to the universal ribosomal protein uS2 family
ZMO1158	COG1794	racemase activity, acting on amino acids and derivatives
ZMO1159	COG1183	phosphatidylcholine synthase activity
ZMO1160	COG0688	phosphatidylethanolamine metabolic process
ZMO1163	COG0704	Plays a role in the regulation of phosphate uptake
ZMO1164	COG0745	RESPONSE REGULATOR receiver
ZMO1165	COG1040	competence protein
ZMO1166	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ZMO1169	COG2971	BadF BadG BcrA BcrD
ZMO1171	COG1472	Belongs to the glycosyl hydrolase 3 family
ZMO1172	COG3724	N-succinylarginine dihydrolase activity
ZMO1176	COG2205	protein histidine kinase activity
ZMO1178	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ZMO1179	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ZMO1182	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ZMO1187	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ZMO1188	COG2226	methyltransferase
ZMO1189	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ZMO1190	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ZMO1191	COG0756	dUTP diphosphatase activity
ZMO1192	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ZMO1193	COG1754	DNA topoisomerase type I activity
ZMO1193	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ZMO1194	COG0758	DNA mediated transformation
ZMO1195	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ZMO1196	COG2814	Major facilitator Superfamily
ZMO1197	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ZMO1198	COG0156	8-amino-7-oxononanoate synthase activity
ZMO1201	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ZMO1202	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ZMO1207	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ZMO1209	COG3158	transport of potassium into the cell
ZMO1212	COG0166	Belongs to the GPI family
ZMO1214	COG0513	Belongs to the DEAD box helicase family
ZMO1218	COG0805	protein transport
ZMO1219	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ZMO1220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ZMO1223	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ZMO1225	COG0360	Binds together with S18 to 16S ribosomal RNA
ZMO1226	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ZMO1227	COG0359	binds to the 23S rRNA
ZMO1228	COG4948	Mandelate Racemase Muconate Lactonizing
ZMO1229	COG0302	gtp cyclohydrolase
ZMO1231	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ZMO1231	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ZMO1234	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ZMO1236	COG1064	alcohol dehydrogenase
ZMO1237	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ZMO1240	COG0588	phosphoglycerate mutase activity
ZMO1242	COG2866	Carboxypeptidase
ZMO1246	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ZMO1253	COG3088	subunit of a heme lyase
ZMO1254	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ZMO1255	COG1138	Cytochrome C-type biogenesis protein
ZMO1256	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ZMO1258	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ZMO1260	COG4771	TonB-dependent receptor
ZMO1261	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ZMO1262	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ZMO1263	COG1116	anion transmembrane transporter activity
ZMO1264	COG4948	Mandelate Racemase Muconate Lactonizing
ZMO1267	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ZMO1267	COG0519	Catalyzes the synthesis of GMP from XMP
ZMO1270	COG0156	8-amino-7-oxononanoate synthase activity
ZMO1271	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ZMO1271	COG1648	precorrin-2 dehydrogenase activity
ZMO1272	COG1012	belongs to the aldehyde dehydrogenase family
ZMO1275	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ZMO1277	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ZMO1278	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ZMO1279	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ZMO1287	COG0438	transferase activity, transferring glycosyl groups
ZMO1288	COG2223	nitrite transmembrane transporter activity
ZMO1289	COG2261	transglycosylase associated protein
ZMO1294	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
ZMO1295	COG0602	queuosine metabolic process
ZMO1302	COG0321	lipoyl(octanoyl) transferase activity
ZMO1303	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ZMO1306	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ZMO1307	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
ZMO1307	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
ZMO1309	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ZMO1311	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ZMO1312	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ZMO1313	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ZMO1314	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ZMO1316	COG2244	polysaccharide biosynthetic process
ZMO1317	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ZMO1318	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ZMO1320	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ZMO1322	COG0745	RESPONSE REGULATOR receiver
ZMO1323	COG0642	Histidine kinase
ZMO1324	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ZMO1325	COG1660	Displays ATPase and GTPase activities
ZMO1328	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ZMO1329	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ZMO1331	COG0668	transmembrane transport
ZMO1334	COG2353	YceI-like domain
ZMO1335	COG0655	NAD(P)H dehydrogenase (quinone) activity
ZMO1336	COG0583	DNA-binding transcription factor activity
ZMO1337	COG1741	Belongs to the pirin family
ZMO1338	COG1280	lysine exporter protein (LysE YggA)
ZMO1341	COG2321	neutral zinc metallopeptidase
ZMO1345	COG0308	aminopeptidase N
ZMO1348	COG0024	Methionine aminopeptidase
ZMO1350	COG1058	Belongs to the CinA family
ZMO1350	COG1546	Belongs to the CinA family
ZMO1352	COG0670	Belongs to the BI1 family
ZMO1353	COG4702	Belongs to the UPF0303 family
ZMO1354	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
ZMO1354	COG2885	chlorophyll binding
ZMO1355	COG0488	(ABC) transporter
ZMO1356	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ZMO1358	COG0268	Binds directly to 16S ribosomal RNA
ZMO1360	COG3961	Belongs to the TPP enzyme family
ZMO1364	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ZMO1365	COG3706	GGDEF domain
ZMO1366	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ZMO1372	COG0300	oxidoreductase activity
ZMO1374	COG1090	epimerase
ZMO1375	COG0571	ribonuclease III activity
ZMO1382	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ZMO1384	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ZMO1388	COG0405	Gamma-glutamyltransferase
ZMO1401	COG0708	Exodeoxyribonuclease III
ZMO1402	COG0316	Belongs to the HesB IscA family
ZMO1403	COG0739	heme binding
ZMO1405	COG0784	Response regulator, receiver
ZMO1406	COG0596	Alpha beta hydrolase
ZMO1407	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ZMO1410	COG2193	ferroxidase activity
ZMO1412	COG4957	zinc ion binding
ZMO1414	COG1214	PFAM Peptidase M22, glycoprotease
ZMO1417	COG0513	Belongs to the DEAD box helicase family
ZMO1419	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ZMO1420	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ZMO1421	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ZMO1422	COG0612	Peptidase, M16
ZMO1423	COG0612	Peptidase, M16
ZMO1425	COG0352	thiamine-phosphate diphosphorylase activity
ZMO1426	COG2003	Belongs to the UPF0758 family
ZMO1428	COG1597	lipid kinase activity
ZMO1435	COG0495	leucyl-tRNA aminoacylation
ZMO1439	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ZMO1443	COG2244	polysaccharide biosynthetic process
ZMO1446	COG0752	glycyl-tRNA synthetase alpha subunit
ZMO1449	COG0246	Mannitol dehydrogenase
ZMO1450	COG0415	Belongs to the DNA photolyase family
ZMO1452	COG2814	Major facilitator Superfamily
ZMO1455	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ZMO1465	COG0814	amino acid
ZMO1478	COG0363	glucosamine-6-phosphate deaminase activity
ZMO1481	COG0045	succinate-CoA ligase (ADP-forming) activity
ZMO1484	COG0210	DNA helicase
ZMO1487	COG2200	EAL domain
ZMO1487	COG2199	diguanylate cyclase activity
ZMO1488	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ZMO1489	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ZMO1494	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ZMO1495	COG2096	Adenosyltransferase
ZMO1496	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ZMO1497	COG0531	amino acid
ZMO1499	COG0140	phosphoribosyl-ATP diphosphatase activity
ZMO1500	COG0107	imidazoleglycerol-phosphate synthase activity
ZMO1501	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ZMO1502	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ZMO1503	COG0131	Imidazoleglycerol-phosphate dehydratase
ZMO1507	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ZMO1508	COG0124	histidyl-tRNA synthetase
ZMO1509	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ZMO1510	COG2890	protein-(glutamine-N5) methyltransferase activity
ZMO1512	COG5265	(ABC) transporter
ZMO1513	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ZMO1513	COG0072	phenylalanine-tRNA ligase activity
ZMO1514	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ZMO1515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ZMO1516	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ZMO1519	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ZMO1525	COG1538	Outer membrane efflux protein
ZMO1529	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ZMO1530	COG0517	IMP dehydrogenase activity
ZMO1530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ZMO1531	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ZMO1532	COG0047	phosphoribosylformylglycinamidine synthase activity
ZMO1538	COG0587	DNA-directed DNA polymerase activity
ZMO1542	COG0629	single-stranded DNA binding
ZMO1548	COG1657	PFAM Prenyltransferase squalene oxidase
ZMO1550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ZMO1551	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ZMO1552	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ZMO1553	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ZMO1557	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ZMO1561	COG4221	oxidoreductase activity
ZMO1562	COG1051	belongs to the nudix hydrolase family
ZMO1566	COG1742	UPF0060 membrane protein
ZMO1569	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ZMO1571	COG1271	oxidase subunit
ZMO1572	COG1294	oxidase, subunit
ZMO1576	COG4221	oxidoreductase activity
ZMO1583	COG0187	DNA topoisomerase II activity
ZMO1584	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ZMO1588	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ZMO1590	COG1127	ABC transporter
ZMO1591	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ZMO1592	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ZMO1596	COG1454	alcohol dehydrogenase
ZMO1598	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ZMO1600	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ZMO1601	COG0328	RNA-DNA hybrid ribonuclease activity
ZMO1603	COG3453	Protein conserved in bacteria
ZMO1603	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ZMO1605	COG0508	dehydrogenase complex catalyzes the overall conversion of
ZMO1605	COG0022	dehydrogenase e1 component
ZMO1606	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ZMO1608	COG0148	phosphopyruvate hydratase activity
ZMO1615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ZMO1618	COG0505	Belongs to the CarA family
ZMO1623	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ZMO1625	COG0594	ribonuclease P activity
ZMO1626	COG0706	membrane insertase activity
ZMO1627	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ZMO1631	COG4774	siderophore transport
ZMO1632	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ZMO1638	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ZMO1639	COG0728	peptidoglycan biosynthetic process
ZMO1640	COG0180	Tryptophanyl-tRNA synthetase
ZMO1642	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ZMO1643	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ZMO1646	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ZMO1648	COG1573	uracil-dna glycosylase
ZMO1649	COG3386	PFAM SMP-30 Gluconolaconase
ZMO1651	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ZMO1654	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ZMO1658	COG0037	tRNA processing
ZMO1661	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ZMO1662	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ZMO1663	COG0799	negative regulation of ribosome biogenesis
ZMO1664	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ZMO1667	COG0793	Belongs to the peptidase S41A family
ZMO1673	COG0656	L-ascorbic acid biosynthetic process
ZMO1677	COG1194	a g-specific adenine glycosylase
ZMO1678	COG0077	Prephenate dehydratase
ZMO1681	COG2985	domain, Protein
ZMO1683	COG0252	asparaginase activity
ZMO1685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ZMO1687	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ZMO1688	COG0354	folic acid binding
ZMO1689	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ZMO1690	COG0484	heat shock protein binding
ZMO1691	COG1295	ribonuclease BN
ZMO1692	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ZMO1693	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ZMO1697	COG1733	regulation of RNA biosynthetic process
ZMO1699	COG0708	Exodeoxyribonuclease III
ZMO1701	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ZMO1702	COG1674	ftsk spoiiie
ZMO1703	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ZMO1707	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ZMO1708	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ZMO1709	COG0736	holo-[acyl-carrier-protein] synthase activity
ZMO1710	COG0681	Belongs to the peptidase S26 family
ZMO1711	COG0628	permease
ZMO1713	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ZMO1719	COG1940	carbohydrate kinase activity
ZMO1720	COG1758	RNA polymerase activity
ZMO1722	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ZMO1724	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ZMO1725	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ZMO1727	COG0436	Aminotransferase
ZMO1730	COG1045	serine acetyltransferase
ZMO1733	COG0583	DNA-binding transcription factor activity
ZMO1738	COG3279	Response regulator of the LytR AlgR family
ZMO1739	COG3275	phosphorelay sensor kinase activity
ZMO1741	COG0481	GTPase activity
ZMO1745	COG0646	methionine synthase
ZMO1745	COG1410	methionine synthase
ZMO1749	COG2853	Lipoprotein
ZMO1754	COG1012	belongs to the aldehyde dehydrogenase family
ZMO1755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ZMO1756	COG2610	gluconate transmembrane transporter activity
ZMO1757	COG3265	gluconokinase activity
ZMO1758	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ZMO1761	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ZMO1762	COG0792	nuclease activity
ZMO1764	COG2989	Protein conserved in bacteria
ZMO1767	COG1210	Utp--glucose-1-phosphate uridylyltransferase
ZMO1768	COG0019	diaminopimelate decarboxylase activity
ZMO1770	COG0165	Argininosuccinate lyase
ZMO1771	COG1979	alcohol dehydrogenase
ZMO1772	COG1063	alcohol dehydrogenase
ZMO1773	COG0656	L-ascorbic acid biosynthetic process
ZMO1781	COG0668	transmembrane transport
ZMO1790	COG1132	(ABC) transporter
ZMO1792	COG0129	dihydroxy-acid dehydratase activity
ZMO1793	COG0583	DNA-binding transcription factor activity
ZMO1796	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ZMO1797	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ZMO1798	COG0539	negative regulation of cytoplasmic translation
ZMO1801	COG0776	regulation of translation
ZMO1804	COG0531	amino acid
ZMO1805	COG0546	phosphoglycolate phosphatase activity
ZMO1806	COG0110	maltose O-acetyltransferase activity
ZMO1811	COG4658	electron transport chain
ZMO1813	COG2878	Part of a membrane complex involved in electron transport
ZMO1814	COG4657	Part of a membrane complex involved in electron transport
ZMO1816	COG3604	Transcriptional regulator
ZMO1817	COG0535	radical SAM domain protein
ZMO1818	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
ZMO1820	COG5554	nitrogen fixation
ZMO1822	COG4774	siderophore transport
ZMO1823	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
ZMO1824	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ZMO1825	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ZMO1826	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ZMO1827	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
ZMO1828	COG1433	Dinitrogenase iron-molybdenum cofactor
ZMO1834	COG1104	cysteine desulfurase activity
ZMO1835	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ZMO1838	COG3585	molybdate ion transport
ZMO1844	COG0673	inositol 2-dehydrogenase activity
ZMO1845	COG2824	Alkylphosphonate utilization operon protein PhnA
ZMO1846	COG1120	ATPase activity
ZMO1851	COG0716	FMN binding
ZMO1853	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ZMO1857	COG0583	DNA-binding transcription factor activity
ZMO1861	COG2070	2-Nitropropane dioxygenase
ZMO1862	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ZMO1867	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ZMO1873	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ZMO1878	COG0525	valine-tRNA ligase activity
ZMO1879	COG0113	porphobilinogen synthase activity
ZMO1882	COG3180	Ammonia monooxygenase
ZMO1883	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ZMO1884	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ZMO1885	COG1902	pentaerythritol trinitrate reductase activity
ZMO1886	COG3180	Ammonia monooxygenase
ZMO1887	COG1335	isochorismatase
ZMO1890	COG0612	Peptidase, M16
ZMO1895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ZMO1897	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ZMO1899	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ZMO1900	COG0416	fatty acid biosynthetic process
ZMO1903	COG0181	hydroxymethylbilane synthase activity
ZMO1904	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ZMO1905	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ZMO1906	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ZMO1907	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ZMO1910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ZMO1911	COG0193	aminoacyl-tRNA hydrolase activity
ZMO1912	COG0012	GTP binding
ZMO1913	COG0189	ligase activity
ZMO1915	COG4106	trans-aconitate 2-methyltransferase activity
ZMO1915	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ZMO1917	COG0156	8-amino-7-oxononanoate synthase activity
ZMO1918	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ZMO1923	COG1368	sulfuric ester hydrolase activity
ZMO1927	COG0616	signal peptide processing
ZMO1928	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ZMO1929	COG0459	protein refolding
ZMO1931	COG4804	nuclease activity
ZMO1944	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ZMO1945	COG0384	phenazine biosynthesis protein PhzF
ZMO1948	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ZMO1949	COG2249	NAD(P)H dehydrogenase (quinone) activity
ZMO1952	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ZMO1954	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ZMO1955	COG0281	malic enzyme
ZMO1956	COG0497	DNA recombination
ZMO1957	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ZMO1957	COG0438	transferase activity, transferring glycosyl groups
ZMO1962	COG5002	protein histidine kinase activity
ZMO1963	COG0372	Belongs to the citrate synthase family
ZMO1964	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ZMO1965	COG2333	competence protein COMEC
ZMO1965	COG0658	competence protein
ZMO1970	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ZMO1974	COG0583	DNA-binding transcription factor activity
ZMO1977	COG0477	Major facilitator Superfamily
ZMO1978	COG1475	DNA binding
ZMO1979	COG1192	Involved in chromosome partitioning
ZMO1980	COG0357	Ribosomal RNA small subunit methyltransferase G
ZMO1981	COG0445	tRNA wobble uridine modification
ZMO1983	COG3386	PFAM SMP-30 Gluconolaconase
ZMO1984	COG0667	Aldo Keto reductase
ZMO1986	COG4771	TonB-dependent receptor
ZMO1988	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ZMO1989	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ZMO1992	COG0412	Dienelactone hydrolase
ZMO1996	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ZMO1998	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ZMO2002	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ZMO2003	COG0051	transcription antitermination factor activity, RNA binding
ZMO2004	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ZMO2023	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
ZMO2031	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ZMO2032	COG2003	Belongs to the UPF0758 family