locus-tag	class	description
DSAG12_00002	COG0436	Aminotransferase
DSAG12_00005	COG0071	Belongs to the small heat shock protein (HSP20) family
DSAG12_00010	COG2986	histidine ammonia-lyase
DSAG12_00011	COG1228	amidohydrolase
DSAG12_00012	COG2759	Belongs to the formate--tetrahydrofolate ligase family
DSAG12_00018	COG2226	methyltransferase
DSAG12_00023	COG1606	tRNA processing
DSAG12_00033	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DSAG12_00039	COG2255	four-way junction helicase activity
DSAG12_00044	COG0318	PFAM AMP-dependent synthetase and ligase
DSAG12_00046	COG1086	Polysaccharide biosynthesis protein
DSAG12_00050	COG1073	alpha beta
DSAG12_00051	COG0673	inositol 2-dehydrogenase activity
DSAG12_00053	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSAG12_00053	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSAG12_00058	COG0456	acetyltransferase
DSAG12_00064	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DSAG12_00073	COG0655	NAD(P)H dehydrogenase (quinone) activity
DSAG12_00075	COG0148	phosphopyruvate hydratase activity
DSAG12_00081	COG1960	acyl-CoA dehydrogenase activity
DSAG12_00082	COG2030	dehydratase
DSAG12_00084	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DSAG12_00097	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DSAG12_00107	COG2226	methyltransferase
DSAG12_00110	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DSAG12_00117	COG0430	RNA-3'-phosphate cyclase activity
DSAG12_00118	COG1058	Belongs to the CinA family
DSAG12_00118	COG1546	Belongs to the CinA family
DSAG12_00119	COG1056	cytidyltransferase-related domain
DSAG12_00119	COG1051	belongs to the nudix hydrolase family
DSAG12_00127	COG0525	valine-tRNA ligase activity
DSAG12_00129	COG2267	carboxylic ester hydrolase activity
DSAG12_00132	COG0037	tRNA processing
DSAG12_00133	COG1042	CoA-binding domain protein
DSAG12_00133	COG0045	succinate-CoA ligase (ADP-forming) activity
DSAG12_00133	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSAG12_00137	COG0574	Belongs to the PEP-utilizing enzyme family
DSAG12_00137	COG3848	Pyruvate phosphate dikinase
DSAG12_00143	COG0495	leucyl-tRNA aminoacylation
DSAG12_00148	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DSAG12_00154	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSAG12_00155	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSAG12_00156	COG0427	acetyl-CoA hydrolase
DSAG12_00158	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DSAG12_00159	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DSAG12_00163	COG0312	modulator of DNA gyrase
DSAG12_00164	COG0045	succinate-CoA ligase (ADP-forming) activity
DSAG12_00164	COG1042	CoA-binding domain protein
DSAG12_00164	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSAG12_00165	COG0857	belongs to the CobB CobQ family
DSAG12_00174	COG0822	iron-sulfur transferase activity
DSAG12_00177	COG1136	(ABC) transporter
DSAG12_00183	COG0546	phosphoglycolate phosphatase activity
DSAG12_00187	COG1136	(ABC) transporter
DSAG12_00192	COG0006	proline dipeptidase activity
DSAG12_00195	COG1342	Belongs to the UPF0251 family
DSAG12_00197	COG1522	sequence-specific DNA binding
DSAG12_00200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DSAG12_00204	COG0318	PFAM AMP-dependent synthetase and ligase
DSAG12_00213	COG0640	Transcriptional regulator
DSAG12_00222	COG0596	Alpha beta hydrolase
DSAG12_00231	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DSAG12_00245	COG4555	ABC transporter
DSAG12_00252	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSAG12_00253	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSAG12_00254	COG1144	Oxidoreductase
DSAG12_00268	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSAG12_00271	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
DSAG12_00273	COG1122	ATPase activity
DSAG12_00278	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DSAG12_00279	COG1028	Short-chain dehydrogenase reductase Sdr
DSAG12_00285	COG0167	dihydroorotate dehydrogenase activity
DSAG12_00287	COG1032	radical SAM domain protein
DSAG12_00293	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DSAG12_00295	COG1111	helicase
DSAG12_00295	COG1205	dead DEAH box helicase
DSAG12_00302	COG2815	serine threonine protein kinase
DSAG12_00302	COG0515	serine threonine protein kinase
DSAG12_00305	COG0596	Alpha beta hydrolase
DSAG12_00311	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DSAG12_00325	COG0596	Alpha beta hydrolase
DSAG12_00329	COG0252	asparaginase activity
DSAG12_00330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DSAG12_00337	COG2414	aldehyde ferredoxin oxidoreductase
DSAG12_00339	COG0252	asparaginase activity
DSAG12_00349	COG0464	growth
DSAG12_00353	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DSAG12_00358	COG4166	transmembrane transport
DSAG12_00362	COG1132	(ABC) transporter
DSAG12_00363	COG1132	(ABC) transporter
DSAG12_00377	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DSAG12_00381	COG0085	RNA polymerase activity
DSAG12_00384	COG1335	isochorismatase
DSAG12_00385	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DSAG12_00392	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DSAG12_00397	COG0640	Transcriptional regulator
DSAG12_00400	COG2226	methyltransferase
DSAG12_00403	COG1131	(ABC) transporter
DSAG12_00405	COG0604	alcohol dehydrogenase
DSAG12_00417	COG0455	bacterial-type flagellum organization
DSAG12_00418	COG0489	protein tyrosine kinase activity
DSAG12_00439	COG1085	galactose-1-phosphate uridylyltransferase
DSAG12_00441	COG0318	PFAM AMP-dependent synthetase and ligase
DSAG12_00448	COG1924	4 iron, 4 sulfur cluster binding
DSAG12_00449	COG0714	Associated with various cellular activities
DSAG12_00451	COG1970	mechanosensitive ion channel activity
DSAG12_00455	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSAG12_00456	COG1144	Oxidoreductase
DSAG12_00457	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSAG12_00458	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSAG12_00465	COG1215	transferase activity, transferring glycosyl groups
DSAG12_00466	COG0646	methionine synthase
DSAG12_00466	COG1410	methionine synthase
DSAG12_00468	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DSAG12_00469	COG1607	acyl-coa hydrolase
DSAG12_00470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSAG12_00474	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DSAG12_00476	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DSAG12_00477	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DSAG12_00487	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DSAG12_00495	COG1640	4-alpha-glucanotransferase
DSAG12_00497	COG1196	nuclear chromosome segregation
DSAG12_00497	COG1196	nuclear chromosome segregation
DSAG12_00502	COG1278	Cold shock
DSAG12_00508	COG1362	aminopeptidase activity
DSAG12_00511	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSAG12_00511	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DSAG12_00512	COG0531	amino acid
DSAG12_00516	COG0481	GTPase activity
DSAG12_00531	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DSAG12_00532	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
DSAG12_00539	COG1185	polyribonucleotide nucleotidyltransferase activity
DSAG12_00540	COG1185	polyribonucleotide nucleotidyltransferase activity
DSAG12_00546	COG0456	acetyltransferase
DSAG12_00549	COG0308	aminopeptidase N
DSAG12_00551	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DSAG12_00552	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSAG12_00553	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DSAG12_00554	COG1193	negative regulation of DNA recombination
DSAG12_00557	COG0604	alcohol dehydrogenase
DSAG12_00566	COG1760	l-serine dehydratase
DSAG12_00567	COG1760	l-serine dehydratase
DSAG12_00568	COG3246	L-lysine catabolic process to acetate
DSAG12_00569	COG1607	acyl-coa hydrolase
DSAG12_00574	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DSAG12_00579	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DSAG12_00581	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DSAG12_00589	COG0023	Translation Initiation Factor
DSAG12_00590	COG1078	dGTPase activity
DSAG12_00596	COG0528	UMP kinase activity
DSAG12_00615	COG1078	dGTPase activity
DSAG12_00623	COG1794	racemase activity, acting on amino acids and derivatives
DSAG12_00642	COG1694	Mazg nucleotide pyrophosphohydrolase
DSAG12_00646	COG0438	transferase activity, transferring glycosyl groups
DSAG12_00648	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DSAG12_00656	COG0037	tRNA processing
DSAG12_00659	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSAG12_00660	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DSAG12_00661	COG0301	tRNA thio-modification
DSAG12_00667	COG0459	protein refolding
DSAG12_00675	COG1100	Small GTP-binding protein
DSAG12_00693	COG0089	rRNA binding
DSAG12_00699	COG1404	Belongs to the peptidase S8 family
DSAG12_00712	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
DSAG12_00716	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DSAG12_00717	COG0537	adenosine 5'-monophosphoramidase activity
DSAG12_00721	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DSAG12_00731	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DSAG12_00732	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
DSAG12_00734	COG0288	reversible hydration of carbon dioxide
DSAG12_00735	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DSAG12_00738	COG3842	ATPase activity
DSAG12_00739	COG3842	ATPase activity
DSAG12_00756	COG0515	serine threonine protein kinase
DSAG12_00756	COG2815	serine threonine protein kinase
DSAG12_00760	COG0343	queuine tRNA-ribosyltransferase activity
DSAG12_00771	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DSAG12_00774	COG1260	myo-inositol-1-phosphate synthase
DSAG12_00785	COG2030	dehydratase
DSAG12_00786	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DSAG12_00787	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSAG12_00789	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DSAG12_00791	COG0009	L-threonylcarbamoyladenylate synthase
DSAG12_00800	COG2814	Major facilitator Superfamily
DSAG12_00808	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSAG12_00809	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSAG12_00816	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DSAG12_00820	COG1196	nuclear chromosome segregation
DSAG12_00820	COG1196	nuclear chromosome segregation
DSAG12_00837	COG2211	Major facilitator Superfamily
DSAG12_00845	COG0647	UMP catabolic process
DSAG12_00846	COG0243	molybdopterin cofactor binding
DSAG12_00855	COG1011	Hydrolase
DSAG12_00859	COG1924	4 iron, 4 sulfur cluster binding
DSAG12_00866	COG2084	Dehydrogenase
DSAG12_00867	COG2814	Major facilitator Superfamily
DSAG12_00870	COG0300	oxidoreductase activity
DSAG12_00873	COG1121	(ABC) transporter
DSAG12_00874	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DSAG12_00876	COG1321	iron dependent repressor
DSAG12_00879	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DSAG12_00879	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
DSAG12_00883	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSAG12_00883	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSAG12_00884	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DSAG12_00885	COG0396	ATPase activity
DSAG12_00886	COG0719	Fe-S assembly protein
DSAG12_00889	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DSAG12_00893	COG1363	Peptidase, m42
DSAG12_00901	COG0037	tRNA processing
DSAG12_00904	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DSAG12_00907	COG0322	excinuclease ABC activity
DSAG12_00909	COG2190	(PTS) system
DSAG12_00909	COG2211	Major facilitator Superfamily
DSAG12_00910	COG0006	proline dipeptidase activity
DSAG12_00916	COG0432	Pfam Uncharacterised protein family UPF0047
DSAG12_00917	COG0180	Tryptophanyl-tRNA synthetase
DSAG12_00921	COG4279	zinc finger
DSAG12_00922	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DSAG12_00925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DSAG12_00943	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DSAG12_00944	COG0489	protein tyrosine kinase activity
DSAG12_00950	COG0584	glycerophosphoryl diester phosphodiesterase
DSAG12_00956	COG5277	cytoskeleton organization
DSAG12_00962	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DSAG12_00969	COG0424	maF-like protein
DSAG12_00971	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSAG12_00973	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DSAG12_00980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DSAG12_00986	COG0546	phosphoglycolate phosphatase activity
DSAG12_00989	COG1872	DUF167
DSAG12_00998	COG1028	Short-chain dehydrogenase reductase Sdr
DSAG12_01007	COG0667	Aldo Keto reductase
DSAG12_01028	COG1028	Short-chain dehydrogenase reductase Sdr
DSAG12_01042	COG0318	PFAM AMP-dependent synthetase and ligase
DSAG12_01046	COG0017	Asparaginyl-tRNA synthetase
DSAG12_01050	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSAG12_01052	COG2814	Major facilitator Superfamily
DSAG12_01066	COG0215	cysteine-tRNA ligase activity
DSAG12_01072	COG2270	Major facilitator Superfamily
DSAG12_01076	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DSAG12_01077	COG2217	Heavy metal translocating P-type atpase
DSAG12_01081	COG1131	(ABC) transporter
DSAG12_01082	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DSAG12_01083	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSAG12_01084	COG1846	Transcriptional regulator
DSAG12_01085	COG1136	(ABC) transporter
DSAG12_01087	COG0028	Belongs to the TPP enzyme family
DSAG12_01095	COG0822	iron-sulfur transferase activity
DSAG12_01107	COG1592	Rubrerythrin
DSAG12_01108	COG2033	superoxide reductase activity
DSAG12_01112	COG1013	pyruvate-flavodoxin oxidoreductase activity
DSAG12_01118	COG1331	Highly conserved protein containing a thioredoxin domain
DSAG12_01122	COG1960	acyl-CoA dehydrogenase activity
DSAG12_01128	COG0426	domain, Protein
DSAG12_01128	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DSAG12_01131	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DSAG12_01134	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DSAG12_01137	COG2048	Heterodisulfide reductase, subunit B
DSAG12_01138	COG0247	lactate metabolic process
DSAG12_01138	COG2181	nitrate reductase activity
DSAG12_01139	COG0425	Belongs to the sulfur carrier protein TusA family
DSAG12_01143	COG2210	Belongs to the sulfur carrier protein TusA family
DSAG12_01146	COG2048	Heterodisulfide reductase, subunit B
DSAG12_01157	COG0473	3-isopropylmalate dehydrogenase activity
DSAG12_01161	COG2048	Heterodisulfide reductase, subunit B
DSAG12_01169	COG0200	Binds to the 23S rRNA
DSAG12_01171	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DSAG12_01175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DSAG12_01176	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DSAG12_01178	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DSAG12_01181	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DSAG12_01182	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DSAG12_01184	COG0255	Belongs to the universal ribosomal protein uL29 family
DSAG12_01185	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DSAG12_01188	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DSAG12_01199	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DSAG12_01204	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DSAG12_01206	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DSAG12_01209	COG1304	FMN binding
DSAG12_01211	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DSAG12_01214	COG3425	synthase
DSAG12_01215	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DSAG12_01221	COG2030	dehydratase
DSAG12_01222	COG0110	maltose O-acetyltransferase activity
DSAG12_01228	COG1012	belongs to the aldehyde dehydrogenase family
DSAG12_01228	COG1454	alcohol dehydrogenase
DSAG12_01229	COG0318	PFAM AMP-dependent synthetase and ligase
DSAG12_01232	COG2267	carboxylic ester hydrolase activity
DSAG12_01251	COG1850	ribulose-bisphosphate carboxylase activity
DSAG12_01252	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DSAG12_01253	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DSAG12_01255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DSAG12_01256	COG0459	protein refolding
DSAG12_01264	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DSAG12_01265	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
DSAG12_01271	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
DSAG12_01271	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSAG12_01276	COG1131	(ABC) transporter
DSAG12_01280	COG1418	mRNA catabolic process
DSAG12_01288	COG1047	Peptidyl-prolyl cis-trans
DSAG12_01289	COG0561	phosphatase activity
DSAG12_01291	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DSAG12_01296	COG1024	Enoyl-CoA hydratase
DSAG12_01297	COG1960	acyl-CoA dehydrogenase activity
DSAG12_01298	COG2211	Major facilitator Superfamily
DSAG12_01301	COG0492	ferredoxin-NADP+ reductase activity
DSAG12_01303	COG0318	PFAM AMP-dependent synthetase and ligase
DSAG12_01304	COG1404	Belongs to the peptidase S8 family
DSAG12_01306	COG0649	NAD binding
DSAG12_01309	COG0756	dUTP diphosphatase activity
DSAG12_01312	COG1104	cysteine desulfurase activity
DSAG12_01313	COG0018	arginyl-trna synthetase
DSAG12_01314	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DSAG12_01317	COG0442	prolyl-tRNA aminoacylation
DSAG12_01322	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DSAG12_01325	COG1960	acyl-CoA dehydrogenase activity
DSAG12_01329	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
DSAG12_01333	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DSAG12_01334	COG2204	response regulator
DSAG12_01335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DSAG12_01335	COG4191	Histidine kinase
DSAG12_01338	COG0827	DNA restriction-modification system
DSAG12_01343	COG0697	spore germination
DSAG12_01346	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSAG12_01346	COG0731	radical SAM domain protein
DSAG12_01347	COG2211	Major facilitator Superfamily
DSAG12_01351	COG2211	Major facilitator Superfamily
DSAG12_01355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DSAG12_01359	COG0745	RESPONSE REGULATOR receiver
DSAG12_01367	COG1363	Peptidase, m42
DSAG12_01377	COG0300	oxidoreductase activity
DSAG12_01378	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSAG12_01381	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
DSAG12_01389	COG0384	phenazine biosynthesis protein PhzF
DSAG12_01406	COG4991	sh3 domain protein
DSAG12_01406	COG0515	serine threonine protein kinase
DSAG12_01406	COG3064	Membrane
DSAG12_01410	COG0460	homoserine dehydrogenase
DSAG12_01413	COG0708	Exodeoxyribonuclease III
DSAG12_01417	COG1028	Short-chain dehydrogenase reductase Sdr
DSAG12_01425	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DSAG12_01427	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DSAG12_01434	COG1378	Sugar-specific transcriptional regulator TrmB
DSAG12_01435	COG0709	Synthesizes selenophosphate from selenide and ATP
DSAG12_01462	COG2267	carboxylic ester hydrolase activity
DSAG12_01466	COG0519	Catalyzes the synthesis of GMP from XMP
DSAG12_01466	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DSAG12_01471	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
DSAG12_01476	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DSAG12_01487	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DSAG12_01495	COG1132	(ABC) transporter
DSAG12_01503	COG1543	Belongs to the glycosyl hydrolase 57 family
DSAG12_01504	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSAG12_01505	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DSAG12_01514	COG2078	PFAM AMMECR1 domain protein
DSAG12_01516	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DSAG12_01522	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DSAG12_01525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DSAG12_01527	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DSAG12_01528	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSAG12_01534	COG0519	Catalyzes the synthesis of GMP from XMP
DSAG12_01536	COG4412	M6 family metalloprotease domain protein
DSAG12_01536	COG3291	Pkd domain containing protein
DSAG12_01544	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DSAG12_01545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DSAG12_01548	COG0312	modulator of DNA gyrase
DSAG12_01549	COG0312	modulator of DNA gyrase
DSAG12_01552	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSAG12_01563	COG1132	(ABC) transporter
DSAG12_01569	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DSAG12_01583	COG0601	transmembrane transport
DSAG12_01588	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DSAG12_01592	COG0202	RNA polymerase activity
DSAG12_01595	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSAG12_01596	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DSAG12_01597	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DSAG12_01605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DSAG12_01613	COG1615	UPF0182 protein
DSAG12_01617	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DSAG12_01619	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DSAG12_01621	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
DSAG12_01621	COG0028	Belongs to the TPP enzyme family
DSAG12_01625	COG0459	protein refolding
DSAG12_01629	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DSAG12_01632	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DSAG12_01638	COG2962	Rard protein
DSAG12_01642	COG1918	ferrous iron import across plasma membrane
DSAG12_01642	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DSAG12_01644	COG3360	Dodecin
DSAG12_01649	COG1122	ATPase activity
DSAG12_01652	COG0310	cobalt ion transport
DSAG12_01657	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DSAG12_01660	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
DSAG12_01661	COG2252	PERMEase
DSAG12_01686	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DSAG12_01693	COG1269	ATP hydrolysis coupled proton transport
DSAG12_01694	COG1394	ATPase activity, coupled to movement of substances
DSAG12_01695	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
DSAG12_01716	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DSAG12_01717	COG2211	Major facilitator Superfamily
DSAG12_01720	COG0463	Glycosyl transferase, family 2
DSAG12_01721	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
DSAG12_01725	COG2211	Major facilitator Superfamily
DSAG12_01733	COG1136	(ABC) transporter
DSAG12_01736	COG0281	malic enzyme
DSAG12_01738	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSAG12_01740	COG1473	amidohydrolase
DSAG12_01745	COG1028	Short-chain dehydrogenase reductase Sdr
DSAG12_01746	COG0584	glycerophosphoryl diester phosphodiesterase
DSAG12_01759	COG3875	lactate racemase activity
DSAG12_01763	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DSAG12_01763	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DSAG12_01770	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DSAG12_01784	COG1304	FMN binding
DSAG12_01786	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DSAG12_01787	COG0081	regulation of translation
DSAG12_01808	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DSAG12_01809	COG0052	Belongs to the universal ribosomal protein uS2 family
DSAG12_01816	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DSAG12_01819	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DSAG12_01819	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DSAG12_01822	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DSAG12_01832	COG0438	transferase activity, transferring glycosyl groups
DSAG12_01833	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
DSAG12_01833	COG0662	Cupin 2, conserved barrel domain protein
DSAG12_01835	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DSAG12_01836	COG1091	dTDP-4-dehydrorhamnose reductase activity
DSAG12_01838	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
DSAG12_01846	COG0463	Glycosyl transferase, family 2
DSAG12_01847	COG3594	Acyltransferase
DSAG12_01848	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DSAG12_01849	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSAG12_01856	COG2089	acid synthase
DSAG12_01857	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DSAG12_01858	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DSAG12_01860	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSAG12_01861	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DSAG12_01862	COG1086	Polysaccharide biosynthesis protein
DSAG12_01865	COG1216	Glycosyl transferase, family 2
DSAG12_01866	COG0463	Glycosyl transferase, family 2
DSAG12_01875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSAG12_01876	COG1088	dTDP-glucose 4,6-dehydratase activity
DSAG12_01877	COG0438	transferase activity, transferring glycosyl groups
DSAG12_01883	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSAG12_01886	COG0495	leucyl-tRNA aminoacylation
DSAG12_01888	COG2244	polysaccharide biosynthetic process
DSAG12_01892	COG1215	transferase activity, transferring glycosyl groups
DSAG12_01895	COG4750	Nucleotidyl transferase
DSAG12_01897	COG0494	nUDIX hydrolase
DSAG12_01901	COG0535	radical SAM domain protein
DSAG12_01909	COG1574	metal-dependent hydrolase with the TIM-barrel fold
DSAG12_01914	COG2314	TM2 domain
DSAG12_01915	COG0500	methyltransferase
DSAG12_01916	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DSAG12_01919	COG1250	3-hydroxyacyl-CoA dehydrogenase
DSAG12_01921	COG0126	phosphoglycerate kinase activity
DSAG12_01922	COG2183	response to ionizing radiation
DSAG12_01923	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
DSAG12_01923	COG0316	Belongs to the HesB IscA family
DSAG12_01935	COG1691	(AIR) carboxylase
DSAG12_01941	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DSAG12_01942	COG0427	acetyl-CoA hydrolase
DSAG12_01954	COG0546	phosphoglycolate phosphatase activity
DSAG12_01955	COG0123	including yeast histone deacetylase and acetoin utilization protein
DSAG12_01976	COG0604	alcohol dehydrogenase
DSAG12_01980	COG0123	including yeast histone deacetylase and acetoin utilization protein
DSAG12_01984	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSAG12_01993	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DSAG12_01994	COG2211	Major facilitator Superfamily
DSAG12_02000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DSAG12_02001	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DSAG12_02005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DSAG12_02008	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DSAG12_02017	COG0028	Belongs to the TPP enzyme family
DSAG12_02019	COG0129	dihydroxy-acid dehydratase activity
DSAG12_02021	COG2211	Major facilitator Superfamily
DSAG12_02038	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DSAG12_02043	COG0714	Associated with various cellular activities
DSAG12_02054	COG1022	Amp-dependent synthetase and ligase
DSAG12_02055	COG1022	Amp-dependent synthetase and ligase
DSAG12_02057	COG1045	serine acetyltransferase
DSAG12_02060	COG0095	Lipoate-protein ligase
DSAG12_02067	COG0312	modulator of DNA gyrase
DSAG12_02071	COG3118	belongs to the thioredoxin family
DSAG12_02076	COG0149	triose-phosphate isomerase activity
DSAG12_02081	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSAG12_02088	COG1199	ATP-dependent helicase activity
DSAG12_02090	COG0438	transferase activity, transferring glycosyl groups
DSAG12_02094	COG1228	amidohydrolase
DSAG12_02111	COG1132	(ABC) transporter
DSAG12_02112	COG1132	(ABC) transporter
DSAG12_02122	COG2890	protein-(glutamine-N5) methyltransferase activity
DSAG12_02140	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
DSAG12_02152	COG1100	Small GTP-binding protein
DSAG12_02172	COG0513	Belongs to the DEAD box helicase family
DSAG12_02182	COG0017	Asparaginyl-tRNA synthetase
DSAG12_02183	COG0585	pseudouridine synthase activity
DSAG12_02184	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DSAG12_02185	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DSAG12_02186	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DSAG12_02188	COG0215	cysteine-tRNA ligase activity
DSAG12_02195	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DSAG12_02196	COG0047	phosphoribosylformylglycinamidine synthase activity
DSAG12_02197	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSAG12_02201	COG2267	carboxylic ester hydrolase activity
DSAG12_02204	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DSAG12_02205	COG0187	DNA topoisomerase II activity
DSAG12_02206	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DSAG12_02216	COG4895	conserved protein (DUF2196)
DSAG12_02225	COG1605	Chorismate mutase
DSAG12_02225	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DSAG12_02226	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DSAG12_02228	COG0017	Asparaginyl-tRNA synthetase
DSAG12_02229	COG3604	Transcriptional regulator
DSAG12_02232	COG4335	DNA alkylation repair
DSAG12_02235	COG1793	dna ligase
DSAG12_02236	COG1899	peptidyl-lysine modification to peptidyl-hypusine
DSAG12_02237	COG1945	arginine decarboxylase activity
DSAG12_02240	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSAG12_02241	COG1181	Belongs to the D-alanine--D-alanine ligase family
DSAG12_02254	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DSAG12_02259	COG1136	(ABC) transporter
DSAG12_02260	COG1122	ATPase activity
DSAG12_02286	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DSAG12_02294	COG0151	Belongs to the GarS family
DSAG12_02297	COG0492	ferredoxin-NADP+ reductase activity
DSAG12_02300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSAG12_02308	COG1305	Transglutaminase-like
DSAG12_02318	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DSAG12_02322	COG1193	negative regulation of DNA recombination
DSAG12_02326	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DSAG12_02328	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DSAG12_02332	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSAG12_02333	COG3345	alpha-galactosidase
DSAG12_02336	COG0671	phosphoesterase, PA-phosphatase related
DSAG12_02337	COG0183	Belongs to the thiolase family
DSAG12_02339	COG1136	(ABC) transporter
DSAG12_02341	COG1902	pentaerythritol trinitrate reductase activity
DSAG12_02341	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSAG12_02346	COG1160	GTP binding
DSAG12_02347	COG3250	beta-galactosidase activity
DSAG12_02358	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DSAG12_02363	COG2234	aminopeptidase activity
DSAG12_02364	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DSAG12_02366	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DSAG12_02385	COG0306	phosphate transporter
DSAG12_02387	COG0517	IMP dehydrogenase activity
DSAG12_02387	COG0516	GMP reductase activity
DSAG12_02404	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DSAG12_02414	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DSAG12_02415	COG1741	Belongs to the pirin family
DSAG12_02419	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
DSAG12_02429	COG2442	InterPro IPR007367
DSAG12_02431	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSAG12_02436	COG0561	phosphatase activity
DSAG12_02442	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DSAG12_02443	COG0784	Response regulator, receiver
DSAG12_02443	COG2205	protein histidine kinase activity
DSAG12_02443	COG5002	protein histidine kinase activity
DSAG12_02445	COG0745	RESPONSE REGULATOR receiver
DSAG12_02447	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSAG12_02450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DSAG12_02451	COG2205	protein histidine kinase activity
DSAG12_02458	COG2205	protein histidine kinase activity
DSAG12_02458	COG2202	Pas domain
DSAG12_02459	COG4172	Belongs to the ABC transporter superfamily
DSAG12_02467	COG0045	succinate-CoA ligase (ADP-forming) activity
DSAG12_02468	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSAG12_02471	COG1047	Peptidyl-prolyl cis-trans
DSAG12_02473	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DSAG12_02490	COG0551	DNA topoisomerase type I activity
DSAG12_02490	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DSAG12_02498	COG0673	inositol 2-dehydrogenase activity
DSAG12_02503	COG1703	isobutyryl-CoA mutase activity
DSAG12_02504	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
DSAG12_02511	COG0300	oxidoreductase activity
DSAG12_02521	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSAG12_02522	COG0483	inositol monophosphate 1-phosphatase activity
DSAG12_02533	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSAG12_02534	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSAG12_02534	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSAG12_02537	COG3250	beta-galactosidase activity
DSAG12_02570	COG2205	protein histidine kinase activity
DSAG12_02589	COG3384	dioxygenase
DSAG12_02594	COG1136	(ABC) transporter
DSAG12_02596	COG1136	(ABC) transporter
DSAG12_02608	COG1100	Small GTP-binding protein
DSAG12_02612	COG1070	Carbohydrate kinase
DSAG12_02613	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DSAG12_02634	COG1061	Type III restriction enzyme res subunit
DSAG12_02678	COG2211	Major facilitator Superfamily
DSAG12_02681	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DSAG12_02704	COG1882	Formate acetyltransferase
DSAG12_02710	COG3844	kynureninase activity
DSAG12_02715	COG1132	(ABC) transporter
DSAG12_02720	COG0656	L-ascorbic acid biosynthetic process
DSAG12_02727	COG2226	methyltransferase
DSAG12_02735	COG0010	Belongs to the arginase family
DSAG12_02736	COG1899	peptidyl-lysine modification to peptidyl-hypusine
DSAG12_02737	COG0667	Aldo Keto reductase
DSAG12_02738	COG0716	FMN binding
DSAG12_02750	COG0051	transcription antitermination factor activity, RNA binding
DSAG12_02751	COG2813	Specifically methylates the guanine in position
DSAG12_02758	COG0306	phosphate transporter
DSAG12_02765	COG0156	8-amino-7-oxononanoate synthase activity
DSAG12_02766	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSAG12_02772	COG0006	proline dipeptidase activity
DSAG12_02776	COG0398	Pfam SNARE associated Golgi protein
DSAG12_02781	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSAG12_02782	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
DSAG12_02786	COG2373	Large extracellular alpha-helical protein
DSAG12_02801	COG0437	4 iron, 4 sulfur cluster binding
DSAG12_02802	COG2414	aldehyde ferredoxin oxidoreductase
DSAG12_02806	COG0247	lactate metabolic process
DSAG12_02806	COG2181	nitrate reductase activity
DSAG12_02808	COG2878	Part of a membrane complex involved in electron transport
DSAG12_02810	COG0656	L-ascorbic acid biosynthetic process
DSAG12_02817	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DSAG12_02817	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DSAG12_02826	COG2169	Transcriptional regulator
DSAG12_02829	COG0668	transmembrane transport
DSAG12_02832	COG2084	Dehydrogenase
DSAG12_02835	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSAG12_02837	COG4974	Belongs to the 'phage' integrase family
DSAG12_02842	COG0232	Belongs to the dGTPase family. Type 2 subfamily
DSAG12_02850	COG1132	(ABC) transporter
DSAG12_02851	COG1132	(ABC) transporter
DSAG12_02863	COG0697	spore germination
DSAG12_02864	COG2223	nitrite transmembrane transporter activity
DSAG12_02869	COG2211	Major facilitator Superfamily
DSAG12_02870	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DSAG12_02877	COG1396	sequence-specific DNA binding
DSAG12_02880	COG4152	abc transporter atp-binding protein
DSAG12_02888	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
DSAG12_02890	COG0674	pyruvate-flavodoxin oxidoreductase activity
DSAG12_02890	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
DSAG12_02907	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DSAG12_02907	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DSAG12_02910	COG3291	Pkd domain containing protein
DSAG12_02919	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DSAG12_02921	COG1122	ATPase activity
DSAG12_02923	COG0588	phosphoglycerate mutase activity
DSAG12_02924	COG0588	phosphoglycerate mutase activity
DSAG12_02925	COG0588	phosphoglycerate mutase activity
DSAG12_02942	COG0191	fructose-bisphosphate aldolase activity
DSAG12_02943	COG0517	IMP dehydrogenase activity
DSAG12_02943	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DSAG12_02944	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSAG12_02952	COG0277	FAD linked oxidase domain protein
DSAG12_02954	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DSAG12_02961	COG2211	Major facilitator Superfamily
DSAG12_02971	COG1850	ribulose-bisphosphate carboxylase activity
DSAG12_02975	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DSAG12_02983	COG0109	protoheme IX farnesyltransferase activity
DSAG12_02985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DSAG12_02995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DSAG12_02999	COG0784	Response regulator, receiver
DSAG12_02999	COG4191	Histidine kinase
DSAG12_03016	COG1194	a g-specific adenine glycosylase
DSAG12_03022	COG5002	protein histidine kinase activity
DSAG12_03046	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
DSAG12_03051	COG1194	a g-specific adenine glycosylase
DSAG12_03055	COG2195	Cleaves the N-terminal amino acid of tripeptides
DSAG12_03058	COG4152	abc transporter atp-binding protein
DSAG12_03064	COG2814	Major facilitator Superfamily
DSAG12_03077	COG3033	Beta-eliminating lyase
DSAG12_03080	COG1260	myo-inositol-1-phosphate synthase
DSAG12_03084	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DSAG12_03095	COG0444	Belongs to the ABC transporter superfamily
DSAG12_03096	COG4608	Belongs to the ABC transporter superfamily
DSAG12_03100	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DSAG12_03101	COG0492	ferredoxin-NADP+ reductase activity
DSAG12_03108	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
DSAG12_03111	COG4152	abc transporter atp-binding protein
DSAG12_03115	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DSAG12_03117	COG0156	8-amino-7-oxononanoate synthase activity
DSAG12_03122	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DSAG12_03129	COG2814	Major facilitator Superfamily
DSAG12_03136	COG1063	alcohol dehydrogenase
DSAG12_03143	COG0596	Alpha beta hydrolase
DSAG12_03144	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
DSAG12_03145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DSAG12_03148	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
DSAG12_03158	COG0204	Acyl-transferase
DSAG12_03177	COG0519	Catalyzes the synthesis of GMP from XMP
DSAG12_03178	COG1968	undecaprenyl-diphosphatase activity
DSAG12_03181	COG1278	Cold shock
DSAG12_03185	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DSAG12_03190	COG0420	3'-5' exonuclease activity
DSAG12_03191	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
DSAG12_03204	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DSAG12_03210	COG0842	Transport permease protein
DSAG12_03216	COG2211	Major facilitator Superfamily
DSAG12_03217	COG0427	acetyl-CoA hydrolase
DSAG12_03220	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSAG12_03230	COG1960	acyl-CoA dehydrogenase activity
DSAG12_03236	COG0330	HflC and HflK could
DSAG12_03248	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DSAG12_03249	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
DSAG12_03265	COG0456	acetyltransferase
DSAG12_03266	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DSAG12_03269	COG0318	PFAM AMP-dependent synthetase and ligase
DSAG12_03271	COG4667	esterase of the alpha-beta hydrolase superfamily
DSAG12_03273	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DSAG12_03275	COG0215	cysteine-tRNA ligase activity
DSAG12_03286	COG0542	response to heat
DSAG12_03289	COG0358	DNA primase activity
DSAG12_03298	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSAG12_03298	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DSAG12_03304	COG1136	(ABC) transporter
DSAG12_03318	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSAG12_03322	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DSAG12_03323	COG1028	Short-chain dehydrogenase reductase Sdr
DSAG12_03324	COG1902	pentaerythritol trinitrate reductase activity
DSAG12_03324	COG0446	pyridine nucleotide-disulphide oxidoreductase
DSAG12_03327	COG0800	Aldolase
DSAG12_03329	COG0673	inositol 2-dehydrogenase activity
DSAG12_03332	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DSAG12_03336	COG1122	ATPase activity
DSAG12_03340	COG1234	tRNA 3'-trailer cleavage
DSAG12_03342	COG0515	serine threonine protein kinase
DSAG12_03342	COG2815	serine threonine protein kinase
DSAG12_03353	COG0785	Cytochrome C biogenesis protein
DSAG12_03363	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DSAG12_03377	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DSAG12_03394	COG0124	histidyl-tRNA synthetase
DSAG12_03397	COG1278	Cold shock
DSAG12_03398	COG0647	UMP catabolic process
DSAG12_03400	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DSAG12_03407	COG2382	esterase
DSAG12_03409	COG1185	polyribonucleotide nucleotidyltransferase activity
DSAG12_03420	COG1028	Short-chain dehydrogenase reductase Sdr
DSAG12_03421	COG1028	Short-chain dehydrogenase reductase Sdr
DSAG12_03423	COG0584	glycerophosphoryl diester phosphodiesterase
DSAG12_03424	COG1028	Short-chain dehydrogenase reductase Sdr
DSAG12_03425	COG1028	Short-chain dehydrogenase reductase Sdr
DSAG12_03427	COG0300	oxidoreductase activity
DSAG12_03432	COG0436	Aminotransferase
DSAG12_03433	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DSAG12_03434	COG2086	electron transfer activity
DSAG12_03436	COG1960	acyl-CoA dehydrogenase activity
DSAG12_03443	COG1522	sequence-specific DNA binding
DSAG12_03456	COG0546	phosphoglycolate phosphatase activity
DSAG12_03469	COG4608	Belongs to the ABC transporter superfamily
DSAG12_03470	COG0444	Belongs to the ABC transporter superfamily
DSAG12_03489	COG1234	tRNA 3'-trailer cleavage
DSAG12_03495	COG0174	glutamine synthetase
DSAG12_03497	COG0504	CTP synthase activity
DSAG12_03498	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
DSAG12_03507	COG0671	phosphoesterase, PA-phosphatase related
DSAG12_03508	COG1196	nuclear chromosome segregation
DSAG12_03512	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DSAG12_03513	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
DSAG12_03525	COG0584	glycerophosphoryl diester phosphodiesterase
DSAG12_03532	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DSAG12_03533	COG0688	phosphatidylethanolamine metabolic process
DSAG12_03544	COG1763	Mo-molybdopterin cofactor biosynthetic process
DSAG12_03581	COG1100	Small GTP-binding protein
DSAG12_03628	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DSAG12_03638	COG0546	phosphoglycolate phosphatase activity
DSAG12_03639	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DSAG12_03649	COG1136	(ABC) transporter
DSAG12_03663	COG1418	mRNA catabolic process
DSAG12_03665	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DSAG12_03667	COG0066	3-isopropylmalate dehydratase activity
DSAG12_03668	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DSAG12_03671	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSAG12_03672	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DSAG12_03676	COG2197	response regulator
DSAG12_03680	COG1254	Belongs to the acylphosphatase family
DSAG12_03684	COG0072	phenylalanine-tRNA ligase activity
DSAG12_03686	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DSAG12_03689	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DSAG12_03692	COG0571	ribonuclease III activity
DSAG12_03699	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DSAG12_03723	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
DSAG12_03724	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DSAG12_03725	COG2048	Heterodisulfide reductase, subunit B
DSAG12_03727	COG0251	oxidation-reduction process
DSAG12_03730	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DSAG12_03730	COG1522	sequence-specific DNA binding
DSAG12_03732	COG0488	(ABC) transporter
DSAG12_03733	COG1160	GTP binding
DSAG12_03740	COG0174	glutamine synthetase
DSAG12_03741	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DSAG12_03745	COG0058	SHG alpha-glucan phosphorylase activity
DSAG12_03758	COG2226	methyltransferase
DSAG12_03761	COG2814	Major facilitator Superfamily
DSAG12_03771	COG1752	Esterase of the alpha-beta hydrolase superfamily
DSAG12_03773	COG0318	PFAM AMP-dependent synthetase and ligase
DSAG12_03778	COG0318	PFAM AMP-dependent synthetase and ligase
DSAG12_03786	COG3875	lactate racemase activity
DSAG12_03802	COG0574	Belongs to the PEP-utilizing enzyme family
DSAG12_03802	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DSAG12_03806	COG0540	Belongs to the ATCase OTCase family
DSAG12_03813	COG0574	Belongs to the PEP-utilizing enzyme family
DSAG12_03813	COG3848	Pyruvate phosphate dikinase
DSAG12_03817	COG0508	dehydrogenase complex catalyzes the overall conversion of
DSAG12_03818	COG2267	carboxylic ester hydrolase activity
DSAG12_03823	COG1185	polyribonucleotide nucleotidyltransferase activity
DSAG12_03827	COG1522	sequence-specific DNA binding
DSAG12_03831	COG2226	methyltransferase
DSAG12_03832	COG0798	PFAM Bile acid sodium symporter
DSAG12_03844	COG0071	Belongs to the small heat shock protein (HSP20) family
DSAG12_03847	COG0644	oxidoreductase
DSAG12_03862	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DSAG12_03873	COG2814	Major facilitator Superfamily
DSAG12_03874	COG1564	THIamine pyrophosphokinase
DSAG12_03877	COG1178	ABC-type Fe3 transport system permease component
DSAG12_03878	COG3842	ATPase activity
DSAG12_03891	COG0318	PFAM AMP-dependent synthetase and ligase
DSAG12_03893	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DSAG12_03894	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DSAG12_03898	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DSAG12_03904	COG1546	Belongs to the CinA family
DSAG12_03904	COG1058	Belongs to the CinA family
DSAG12_03916	COG1131	(ABC) transporter
DSAG12_03933	COG0735	belongs to the Fur family
DSAG12_03934	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DSAG12_03937	COG2226	methyltransferase
DSAG12_03942	COG0309	Hydrogenase expression formation protein (HypE)
DSAG12_03943	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DSAG12_03944	COG2267	carboxylic ester hydrolase activity
DSAG12_03949	COG2217	Heavy metal translocating P-type atpase
DSAG12_03958	COG2391	methyltransferase activity
DSAG12_03959	COG0425	Belongs to the sulfur carrier protein TusA family
DSAG12_03963	COG1032	radical SAM domain protein
DSAG12_03966	COG2746	aminoglycoside 3-N-acetyltransferase activity