locus-tag	class	description
AArcSl_0004	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AArcSl_0005	ENOG4108DNI	pyridine nucleotide-disulfide oxidoreductase
AArcSl_0012	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AArcSl_0016	ENOG4105C84	Histidine ammonia-lyase
AArcSl_0034	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
AArcSl_0035	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
AArcSl_0038	ENOG4105DBV	ornithine carbamoyltransferase
AArcSl_0039	ENOG4107SBK	Acetylornithine deacetylase
AArcSl_0040	ENOG4105C8Y	Acetylornithine aminotransferase
AArcSl_0041	ENOG4107U4Q	acetylglutamate kinase
AArcSl_0042	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AArcSl_0043	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AArcSl_0046	ENOG4105CH7	arginosuccinase
AArcSl_0047	ENOG4105CDH	Citrulline--aspartate ligase
AArcSl_0049	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AArcSl_0050	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AArcSl_0056	ENOG4105DXX	methyltransferase
AArcSl_0057	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AArcSl_0059	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AArcSl_0061	ENOG4105EAC	phosphoserine phosphatase
AArcSl_0062	ENOG4105DCG	PHP domain protein
AArcSl_0074	ENOG4105F0N	pyrophosphate phospho-hydrolase
AArcSl_0077	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AArcSl_0078	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AArcSl_0079	ENOG4105F0I	Aminotransferase
AArcSl_0080	ENOG4105DDQ	anthranilate synthase
AArcSl_0081	ENOG4105CRQ	synthase (Component I)
AArcSl_0084	ENOG4105C5H	ABC transporter
AArcSl_0088	ENOG4105D1H	recombination factor protein RarA
AArcSl_0089	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AArcSl_0095	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AArcSl_0099	ENOG4105CIG	ABC transporter
AArcSl_0106	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AArcSl_0107	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AArcSl_0108	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AArcSl_0110	ENOG4105NPE	arsR family transcriptional regulator
AArcSl_0118	ENOG4105EJ5	oxidoreductase gamma subunit
AArcSl_0120	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AArcSl_0121	ENOG4105DDK	oxidoreductase, beta subunit
AArcSl_0123	ENOG4108HIY	periplasmic
AArcSl_0128	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AArcSl_0131	ENOG4107QRT	dEAD DEAH box helicase
AArcSl_0139	ENOG4105CUB	amino acid
AArcSl_0143	ENOG4106WTF	Glycosyl transferase, family 2
AArcSl_0145	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AArcSl_0148	ENOG4105C37	(CBS) domain
AArcSl_0149	ENOG4105CJ3	phosphate transporter
AArcSl_0169	ENOG4107TPS	domain protein
AArcSl_0177	ENOG4105DJB	Major Facilitator Superfamily
AArcSl_0184	ENOG4105ERH	Fumarylacetoacetate hydrolase
AArcSl_0187	ENOG4105C59	p-type ATPase
AArcSl_0188	ENOG4105C3M	thioredoxin reductase
AArcSl_0205	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
AArcSl_0206	ENOG410811Q	Ferredoxin
AArcSl_0218	ENOG4105CY0	Metallo-Beta-Lactamase
AArcSl_0224	ENOG4105EM7	Selenocysteine-specific translation elongation factor
AArcSl_0226	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AArcSl_0229	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
AArcSl_0231	ENOG4105C2X	Arabinose 5-phosphate isomerase
AArcSl_0233	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AArcSl_0234	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AArcSl_0240	ENOG4105EAC	phosphoserine phosphatase
AArcSl_0244	ENOG4107RDP	Dehydrogenase
AArcSl_0247	ENOG4105CHR	reductase
AArcSl_0250	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AArcSl_0253	ENOG4108UNV	SUF system FeS assembly protein, NifU family
AArcSl_0257	ENOG4105DBI	uridine monophosphokinase
AArcSl_0258	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AArcSl_0259	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AArcSl_0261	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AArcSl_0262	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AArcSl_0263	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AArcSl_0265	ENOG4108NIW	Leucine export protein LeuE
AArcSl_0268	ENOG4105CSM	endonuclease III
AArcSl_0269	ENOG4105D0M	Protease HtpX homolog
AArcSl_0282	ENOG4105E4F	Isochorismate synthase
AArcSl_0284	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AArcSl_0291	ENOG4105C8J	)-transporter
AArcSl_0294	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AArcSl_0298	ENOG4108EHY	type IV secretion system
AArcSl_0310	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AArcSl_0314	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AArcSl_0315	ENOG4105IIU	Aminopeptidase
AArcSl_0321	ENOG4105UQX	Mate efflux family protein
AArcSl_0322	ENOG4105C28	cystathionine
AArcSl_0329	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AArcSl_0331	ENOG4105CHU	acetyl-coa acetyltransferase
AArcSl_0333	ENOG41088PD	hydrolase
AArcSl_0334	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AArcSl_0336	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AArcSl_0342	ENOG4105C8N	cysteinyl-tRNA synthetase
AArcSl_0347	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AArcSl_0361	ENOG4107ZYJ	bioY protein
AArcSl_0362	ENOG4108JJB	ABC transporter
AArcSl_0364	ENOG4105DF6	Fe-S oxidoreductase
AArcSl_0366	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AArcSl_0370	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AArcSl_0373	ENOG4105C0B	DNA polymerase III (alpha subunit)
AArcSl_0374	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AArcSl_0375	ENOG4105DBV	ornithine carbamoyltransferase
AArcSl_0377	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AArcSl_0379	ENOG4105DYW	oxidoreductase
AArcSl_0380	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AArcSl_0384	ENOG4107BVJ	4,5-dihydroxyphthalate decarboxylase
AArcSl_0391	ENOG4105BZU	Histidine kinase
AArcSl_0394	ENOG4105E5Q	amino acid AbC transporter
AArcSl_0396	ENOG4105E5Q	amino acid AbC transporter
AArcSl_0404	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AArcSl_0406	ENOG4105CPP	Dehydrogenase, E1 component
AArcSl_0407	ENOG4105C7S	Dehydrogenase
AArcSl_0409	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AArcSl_0410	ENOG41082YX	Transcriptional regulator, arsr family
AArcSl_0411	ENOG4105D6J	arsenicaL-resistance protein
AArcSl_0419	ENOG41085FC	arsR family transcriptional regulator
AArcSl_0423	ENOG4107PP3	Acetylornithine deacetylase
AArcSl_0433	ENOG4105BZN	citrate synthase
AArcSl_0434	ENOG4105CHU	acetyl-coa acetyltransferase
AArcSl_0437	ENOG4107QJZ	Glycosyl transferase, family 2
AArcSl_0446	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AArcSl_0451	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AArcSl_0457	ENOG4105C10	Electron transfer flavoprotein
AArcSl_0458	ENOG4105BZJ	Electron transfer flavoprotein
AArcSl_0464	ENOG4108QZ0	Tetrahydromethanopterin S-methyltransferase (EC 2.1.1.86)
AArcSl_0465	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AArcSl_0467	ENOG4105CKU	formyltetrahydrofolate synthetase
AArcSl_0468	ENOG4105F5V	trimethylamine methyltransferase
AArcSl_0469	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AArcSl_0470	ENOG4108Q52	Methyltransferase cognate corrinoid protein
AArcSl_0471	ENOG4105C94	Transporter
AArcSl_0472	ENOG4107YZX	Universal stress protein
AArcSl_0473	ENOG4105C7B	Threonine dehydratase
AArcSl_0474	ENOG41076HS	cation diffusion facilitator family transporter
AArcSl_0475	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AArcSl_0476	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AArcSl_0477	ENOG4105C94	Transporter
AArcSl_0479	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AArcSl_0480	ENOG4105CHM	Aminotransferase
AArcSl_0481	ENOG4105C1G	acyl-Coa dehydrogenase
AArcSl_0483	ENOG4105CPC	Aldo Keto reductase
AArcSl_0486	ENOG4105C26	Dehydrogenase
AArcSl_0487	ENOG41061GT	Aldolase
AArcSl_0488	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AArcSl_0489	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AArcSl_0490	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AArcSl_0492	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AArcSl_0498	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
AArcSl_0507	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AArcSl_0510	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AArcSl_0511	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AArcSl_0513	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
AArcSl_0520	ENOG4105CGP	Urocanate hydratase
AArcSl_0521	ENOG4108903	Formimidoylglutamase
AArcSl_0522	ENOG4105CI2	imidazolone-5-propionate hydrolase
AArcSl_0523	ENOG4106M32	3-dehydroquinate synthase
AArcSl_0526	ENOG4105CX0	fumarate reductase succinate dehydrogenase flavoprotein domain protein
AArcSl_0531	ENOG4105CN9	Peptidase m42 family protein
AArcSl_0539	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AArcSl_0540	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AArcSl_0541	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AArcSl_0545	ENOG4105D7V	transposase
AArcSl_0556	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
AArcSl_0559	ENOG4105D07	Signal peptide peptidase, SppA
AArcSl_0561	ENOG4108Z5K	methylglyoxal synthase
AArcSl_0567	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AArcSl_0568	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
AArcSl_0569	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AArcSl_0570	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AArcSl_0573	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AArcSl_0578	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AArcSl_0580	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AArcSl_0584	ENOG4108IQE	Amp-dependent synthetase and ligase
AArcSl_0589	ENOG4105E2X	shikimate dehydrogenase
AArcSl_0591	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
AArcSl_0593	ENOG4105E3S	small subunit
AArcSl_0594	ENOG4105DPX	Hydrogenase, large subunit
AArcSl_0601	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AArcSl_0602	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
AArcSl_0610	ENOG410800I	Aminomethyltransferase
AArcSl_0611	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AArcSl_0612	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
AArcSl_0614	ENOG4105C4Y	ABC transporter
AArcSl_0618	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AArcSl_0621	ENOG4105C94	Transporter
AArcSl_0622	ENOG4108JB8	alcohol dehydrogenase
AArcSl_0624	ENOG4108N16	Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region
AArcSl_0631	ENOG410906A	Beta-Ig-H3 fasciclin
AArcSl_0632	ENOG4105FAV	ABC, transporter
AArcSl_0633	ENOG4105FDK	ABC transporter
AArcSl_0640	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AArcSl_0644	ENOG4105C0D	helicase
AArcSl_0651	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AArcSl_0658	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AArcSl_0673	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AArcSl_0678	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AArcSl_0679	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AArcSl_0680	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AArcSl_0682	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AArcSl_0685	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AArcSl_0686	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AArcSl_0688	ENOG41082SA	50s ribosomal protein l29
AArcSl_0689	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AArcSl_0691	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AArcSl_0692	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AArcSl_0693	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AArcSl_0694	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AArcSl_0695	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AArcSl_0699	ENOG4107R3N	Filamentation induced by cAMP protein fic
AArcSl_0702	ENOG41080XP	Cbs domain
AArcSl_0703	ENOG4105BZN	citrate synthase
AArcSl_0706	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AArcSl_0709	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AArcSl_0711	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AArcSl_0712	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AArcSl_0719	ENOG4105CQB	FAD linked oxidase domain protein
AArcSl_0720	ENOG4105DAA	L-lactate
AArcSl_0722	ENOG4107QR9	Iron-sulfur cluster binding protein
AArcSl_0740	ENOG4108V1U	phospholipid-binding protein
AArcSl_0745	ENOG4105C59	p-type ATPase
AArcSl_0748	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AArcSl_0766	ENOG4105CEN	a g-specific adenine glycosylase
AArcSl_0769	ENOG4105C9Q	fumarate hydratase class II
AArcSl_0770	ENOG4107XC4	flavin reductase domain protein, FMN-binding
AArcSl_0771	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AArcSl_0773	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
AArcSl_0774	ENOG4105CXT	aspartate transcarbamylase
AArcSl_0778	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AArcSl_0781	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AArcSl_0782	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AArcSl_0783	ENOG4105D6E	homoserine dehydrogenase
AArcSl_0787	ENOG4105BZU	Histidine kinase
AArcSl_0788	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AArcSl_0789	ENOG4105JAB	phenazine biosynthesis protein, phzf family
AArcSl_0791	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AArcSl_0799	ENOG4105C45	hydrogenase expression formation protein (HypE)
AArcSl_0800	ENOG4105C8Y	Acetylornithine aminotransferase
AArcSl_0806	ENOG4105VEQ	Cold shock protein
AArcSl_0807	ENOG4105CSU	acyl-Coa dehydrogenase
AArcSl_0813	ENOG4105C1G	acyl-Coa dehydrogenase
AArcSl_0814	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AArcSl_0816	ENOG41080XP	Cbs domain
AArcSl_0822	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AArcSl_0829	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AArcSl_0830	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AArcSl_0831	ENOG4105CYW	agmatinase
AArcSl_0832	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AArcSl_0838	ENOG4108TQ9	Histidine kinase
AArcSl_0839	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AArcSl_0841	ENOG4105F8C	transglutaminase domain-containing protein
AArcSl_0844	ENOG4105E1F	short-chain dehydrogenase reductase
AArcSl_0846	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
AArcSl_0849	ENOG4105CD3	dihydroorotase
AArcSl_0854	ENOG4105CTD	carboxy-peptidase
AArcSl_0856	ENOG4108TQ9	Histidine kinase
AArcSl_0868	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
AArcSl_0869	ENOG4105EAH	synthase
AArcSl_0877	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
AArcSl_0878	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
AArcSl_0879	ENOG41080XS	Cobyrinic acid ac-diamide synthase
AArcSl_0883	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
AArcSl_0884	ENOG4105WMR	Protein CrcB homolog
AArcSl_0885	ENOG4105WMR	Protein CrcB homolog
AArcSl_0891	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AArcSl_0894	ENOG4107UI5	Transforms N(2)-succinylglutamate into succinate and glutamate (By similarity)
AArcSl_0897	ENOG4105D64	Mechanosensitive ion channel
AArcSl_0902	ENOG4105FE1	phytoene synthase
AArcSl_0903	ENOG4105C1G	acyl-Coa dehydrogenase
AArcSl_0912	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AArcSl_0917	ENOG4107QRT	dEAD DEAH box helicase
AArcSl_0918	ENOG4105CV8	reductase
AArcSl_0919	ENOG4105D7K	pfkb domain protein
AArcSl_0924	ENOG4105E8R	UPF0173 metal-dependent hydrolase
AArcSl_0928	ENOG4105CPQ	Dehydrogenase
AArcSl_0932	ENOG4108VQJ	O-methyltransferase
AArcSl_0935	ENOG4108HKT	sucrose-6-phosphate hydrolase
AArcSl_0936	ENOG4105EDQ	levansucrase EC 2.4.1.10
AArcSl_0938	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AArcSl_0939	ENOG4105DCI	Phosphohydrolase
AArcSl_0946	ENOG4105VEQ	Cold shock protein
AArcSl_0948	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
AArcSl_0954	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
AArcSl_0958	ENOG4105CUB	amino acid
AArcSl_0959	ENOG4105CUB	amino acid
AArcSl_0960	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AArcSl_0964	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
AArcSl_0967	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AArcSl_0969	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AArcSl_0971	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AArcSl_0973	ENOG4107QP6	Xylose isomerase domain protein TIM barrel
AArcSl_0974	ENOG4105CK5	oxidoreductase
AArcSl_0977	ENOG4108IJ9	(ABC) transporter
AArcSl_0978	ENOG4105I1K	ABC transporter
AArcSl_0987	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AArcSl_0988	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AArcSl_0989	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AArcSl_0991	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AArcSl_0994	ENOG4105DPN	Oligoendopeptidase f
AArcSl_0995	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AArcSl_0997	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AArcSl_0998	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AArcSl_1003	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AArcSl_1009	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
AArcSl_1011	ENOG4105D82	Glutamate dehydrogenase
AArcSl_1014	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AArcSl_1015	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AArcSl_1019	ENOG4108EHY	type IV secretion system
AArcSl_1028	ENOG4105CPC	Aldo Keto reductase
AArcSl_1030	ENOG4108PPE	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AArcSl_1032	ENOG4105C5R	Aminotransferase
AArcSl_1036	ENOG4108IUW	ABC transporter
AArcSl_1037	ENOG4107QP8	phosphohexose isomerase
AArcSl_1040	ENOG4108JQ7	(ABC) transporter
AArcSl_1041	ENOG4105C3U	ABC transporter
AArcSl_1042	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AArcSl_1047	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
AArcSl_1048	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AArcSl_1049	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
AArcSl_1050	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AArcSl_1053	ENOG4108UAU	isochorismatase
AArcSl_1058	ENOG4105E39	Enoyl-CoA hydratase
AArcSl_1059	ENOG4105C4K	Nad synthetase
AArcSl_1061	ENOG4105KVH	Transcriptional regulator
AArcSl_1063	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AArcSl_1064	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
AArcSl_1075	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AArcSl_1079	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AArcSl_1082	ENOG4105C12	Phosphoribosylglycinamide synthetase
AArcSl_1083	ENOG4108S4C	acetyltransferase
AArcSl_1089	ENOG4105FEU	K -dependent Na -Ca exchanger
AArcSl_1090	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AArcSl_1091	ENOG4105CHF	Glutathione S-transferase
AArcSl_1093	ENOG4105C3K	feS assembly ATPase SufC
AArcSl_1094	ENOG4105DIW	FeS assembly protein SUFB
AArcSl_1095	ENOG4105DIW	FeS assembly protein SUFB
AArcSl_1098	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AArcSl_1099	ENOG4107YFT	Nadph-dependent fmn reductase
AArcSl_1103	ENOG4105DQ4	alcohol dehydrogenase
AArcSl_1106	ENOG4108I5C	dEAD DEAH box helicase
AArcSl_1107	ENOG4108UHU	Aldolase
AArcSl_1109	ENOG4105CJ1	ABC, transporter
AArcSl_1110	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AArcSl_1111	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AArcSl_1113	ENOG4105D74	hydrolase
AArcSl_1118	ENOG4105C7Z	Conserved Protein
AArcSl_1128	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AArcSl_1130	ENOG4105EW9	transcriptional regulator AsnC family
AArcSl_1131	ENOG4105DQU	oxidoreductase, subunit beta
AArcSl_1132	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AArcSl_1135	ENOG4105E33	succinate dehydrogenase
AArcSl_1139	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AArcSl_1141	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AArcSl_1151	ENOG4105CYN	Serine protein kinase
AArcSl_1156	ENOG4105DG7	nitrate ABC transporter
AArcSl_1157	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AArcSl_1161	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AArcSl_1162	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AArcSl_1171	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AArcSl_1175	ENOG4105F5V	trimethylamine methyltransferase
AArcSl_1178	ENOG4105D5P	Methylmalonyl-coA mutase
AArcSl_1192	ENOG4108IUQ	atp-dependent protease
AArcSl_1196	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AArcSl_1197	ENOG4105CMR	udp-glucose 4-epimerase
AArcSl_1198	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AArcSl_1199	ENOG4105D8X	mechanosensitive ion channel
AArcSl_1205	ENOG4105EWK	phytoene
AArcSl_1208	ENOG4105CRQ	synthase (Component I)
AArcSl_1209	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AArcSl_1210	ENOG4108I0Q	anthranilate phosphoribosyltransferase
AArcSl_1213	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AArcSl_1216	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AArcSl_1222	ENOG4105EHU	Circadian clock protein KaiC
AArcSl_1223	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AArcSl_1237	ENOG4106178	UPF0339 protein
AArcSl_1239	ENOG4107YZX	Universal stress protein
AArcSl_1240	ENOG4107TUY	Histidine kinase
AArcSl_1242	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
AArcSl_1244	ENOG4105ENA	helicase
AArcSl_1251	ENOG4105C32	Amino acid ABC transporter (Permease)
AArcSl_1253	ENOG4105C0Z	ABC transporter
AArcSl_1254	ENOG4108IV0	ABC, transporter
AArcSl_1256	ENOG4105C8J	)-transporter
AArcSl_1259	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AArcSl_1260	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AArcSl_1261	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AArcSl_1262	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AArcSl_1263	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AArcSl_1267	ENOG4105KJM	monovalent cation h antiporter subunit g
AArcSl_1315	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AArcSl_1326	ENOG4105CUT	histidyl-tRNA synthetase
AArcSl_1327	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AArcSl_1334	ENOG4107TIA	phenylalanyl-tRNA synthetase (beta subunit)
AArcSl_1335	ENOG4105K8R	UPF0145 protein
AArcSl_1337	ENOG4105CPC	Aldo Keto reductase
AArcSl_1341	ENOG4105CG3	alpha amylase, catalytic region
AArcSl_1353	ENOG4107QX3	carboxylase
AArcSl_1355	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
AArcSl_1358	ENOG4107QX3	carboxylase
AArcSl_1362	ENOG4105C1G	acyl-Coa dehydrogenase
AArcSl_1365	ENOG4105KJM	monovalent cation h antiporter subunit g
AArcSl_1368	ENOG4105MKQ	Monovalent cation H antiporter subunit C
AArcSl_1369	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AArcSl_1370	ENOG4108JPZ	Monovalent cation H antiporter subunit D
AArcSl_1371	ENOG4105D65	subunit l
AArcSl_1373	ENOG4105VN1	Heat shock protein
AArcSl_1386	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AArcSl_1391	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AArcSl_1394	ENOG4105EG2	ABC transporter, permease
AArcSl_1397	ENOG4108IJ9	(ABC) transporter
AArcSl_1401	ENOG4105BZU	Histidine kinase
AArcSl_1407	ENOG4105EMU	Dehydrogenase
AArcSl_1411	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AArcSl_1414	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AArcSl_1417	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AArcSl_1418	ENOG4105DHP	deoxycytidine triphosphate deaminase
AArcSl_1421	ENOG4105CFG	Acts as a chaperone (By similarity)
AArcSl_1425	ENOG4105BZU	Histidine kinase
AArcSl_1427	ENOG4105EHU	Circadian clock protein KaiC
AArcSl_1431	ENOG4105BZA	Phosphoglycerate kinase
AArcSl_1432	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AArcSl_1438	ENOG4108JIK	carboxylase
AArcSl_1442	ENOG4105CH2	amidohydrolase
AArcSl_1450	ENOG4105C5S	asparaginyl-tRNA synthetase
AArcSl_1452	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AArcSl_1453	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AArcSl_1455	ENOG4107YZX	Universal stress protein
AArcSl_1469	ENOG4108DMA	Nad-dependent epimerase dehydratase
AArcSl_1470	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AArcSl_1478	ENOG4108535	NAD dependent epimerase/dehydratase family
AArcSl_1481	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AArcSl_1482	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AArcSl_1484	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AArcSl_1487	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AArcSl_1488	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
AArcSl_1489	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AArcSl_1492	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AArcSl_1496	ENOG4105BZ1	(ABC) transporter
AArcSl_1498	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AArcSl_1499	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AArcSl_1501	ENOG4108T9Q	UPF0278 protein
AArcSl_1502	ENOG4107W7X	Aldolase
AArcSl_1503	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AArcSl_1506	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AArcSl_1511	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AArcSl_1515	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AArcSl_1516	ENOG4105KZX	Pterin carbinolamine dehydratase
AArcSl_1519	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AArcSl_1523	ENOG4105EEI	dihydropteroate synthase
AArcSl_1524	ENOG4105C3Q	Glycosyl transferase, family 2
AArcSl_1529	ENOG4105K64	Glycosyl transferase, family 2
AArcSl_1531	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AArcSl_1536	ENOG4105CN5	Metallo-Beta-Lactamase
AArcSl_1539	ENOG4105DQU	oxidoreductase, subunit beta
AArcSl_1540	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AArcSl_1546	ENOG4107QI1	Mate efflux family protein
AArcSl_1548	ENOG4105C7B	Threonine dehydratase
AArcSl_1549	ENOG4105CHM	Aminotransferase
AArcSl_1551	ENOG4105MYT	Heat shock protein
AArcSl_1552	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AArcSl_1555	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AArcSl_1561	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
AArcSl_1563	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AArcSl_1565	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AArcSl_1569	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AArcSl_1574	ENOG4105C6T	cysteine synthase
AArcSl_1577	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AArcSl_1581	ENOG4105D0M	Protease HtpX homolog
AArcSl_1584	ENOG4105CJW	magnesium transporter
AArcSl_1585	ENOG4105CJW	magnesium transporter
AArcSl_1589	ENOG4107S6Z	Na H antiporter
AArcSl_1590	ENOG4105D0M	Protease HtpX homolog
AArcSl_1596	ENOG4105CCU	oxidase (Subunit III)
AArcSl_1597	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AArcSl_1603	ENOG4108FPN	Integrase
AArcSl_1615	ENOG4108R4U	Hnh endonuclease
AArcSl_1635	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AArcSl_1636	ENOG41088T4	Helicase IV
AArcSl_1643	ENOG4105CB5	ATP-dependent DNA helicase recG
AArcSl_1662	ENOG41082BV	acetyltransferase
AArcSl_1697	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AArcSl_1705	ENOG4105D52	delta-aminolevulinic acid dehydratase
AArcSl_1709	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AArcSl_1711	ENOG4105D5T	phosphonate abc transporter
AArcSl_1712	ENOG4105S7S	phosphonate abc transporter
AArcSl_1713	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AArcSl_1722	ENOG4107SET	aldo keto reductase
AArcSl_1724	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
AArcSl_1725	ENOG4105DF9	Lipoate-protein, ligase
AArcSl_1726	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AArcSl_1727	ENOG41082IR	Excinuclease ABC C subunit domain protein
AArcSl_1730	ENOG4105E66	phosphoriboisomerase A
AArcSl_1735	ENOG4107XID	2'-5' rna ligase
AArcSl_1738	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AArcSl_1740	ENOG4105C75	arginyL-tRNA synthetase
AArcSl_1743	ENOG410811Q	Ferredoxin
AArcSl_1756	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AArcSl_1758	ENOG4105C5R	Aminotransferase
AArcSl_1759	ENOG4105DTQ	mandelate racemase muconate lactonizing
AArcSl_1760	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
AArcSl_1764	ENOG4105VEQ	Cold shock protein
AArcSl_1765	ENOG4105MRR	Transcriptional regulator (By similarity)
AArcSl_1766	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AArcSl_1769	ENOG4105C5I	Dehydrogenase
AArcSl_1782	ENOG4107TNW	(Aminomethyl transferase) family protein
AArcSl_1784	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AArcSl_1785	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AArcSl_1791	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AArcSl_1792	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AArcSl_1796	ENOG4105CIG	ABC transporter
AArcSl_1807	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AArcSl_1810	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AArcSl_1814	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AArcSl_1817	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AArcSl_1818	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
AArcSl_1820	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AArcSl_1821	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AArcSl_1827	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AArcSl_1828	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AArcSl_1834	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
AArcSl_1835	ENOG4105C28	cystathionine
AArcSl_1839	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
AArcSl_1842	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AArcSl_1848	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AArcSl_1849	ENOG4105DDK	oxidoreductase, beta subunit
AArcSl_1852	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AArcSl_1853	ENOG4105DQU	oxidoreductase, subunit beta
AArcSl_1855	ENOG4108R3D	Electron transport complex
AArcSl_1856	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AArcSl_1857	ENOG4105C10	Electron transfer flavoprotein
AArcSl_1858	ENOG4105BZJ	Electron transfer flavoprotein
AArcSl_1864	ENOG4105C8T	Leucyl-tRNA synthetase
AArcSl_1866	ENOG4105CHR	reductase
AArcSl_1868	ENOG4105C98	muts2 protein
AArcSl_1871	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AArcSl_1872	ENOG4105KFG	YeeE YedE family protein
AArcSl_1873	ENOG4105MD1	YeeE YedE family protein
AArcSl_1874	ENOG4107TPS	domain protein
AArcSl_1875	ENOG4105VFE	sira family
AArcSl_1876	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
AArcSl_1877	ENOG4105K63	Thioredoxin
AArcSl_1881	ENOG4105DWV	Homoserine O-trans-acetylase
AArcSl_1901	ENOG41089UC	methyltransferase, type 11
AArcSl_1904	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AArcSl_1905	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AArcSl_1911	ENOG4107RT3	EamA-like transporter family
AArcSl_1914	ENOG4105C10	Electron transfer flavoprotein
AArcSl_1915	ENOG4105BZJ	Electron transfer flavoprotein
AArcSl_1922	ENOG4105C1Q	protoporphyrinogen oxidase
AArcSl_1924	ENOG4105DTQ	mandelate racemase muconate lactonizing
AArcSl_1934	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AArcSl_1937	ENOG4108IEG	Formate dehydrogenase Alpha subunit
AArcSl_1938	ENOG4105QAX	Iron-sulfur
AArcSl_1941	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
AArcSl_1942	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AArcSl_1944	ENOG4108570	YjeF-related protein N-terminus
AArcSl_1946	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
AArcSl_1948	ENOG4105FF2	Type I DHQase
AArcSl_1950	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AArcSl_1951	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AArcSl_1955	ENOG4105E39	Enoyl-CoA hydratase
AArcSl_1957	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
AArcSl_1959	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AArcSl_1968	ENOG41068T5	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT (By similarity)
AArcSl_1973	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AArcSl_1979	ENOG4105BZ9	Cytochrome C oxidase, subunit I
AArcSl_1982	ENOG4105K63	Thioredoxin
AArcSl_1983	ENOG4107EPV	Aminotransferase class V
AArcSl_1985	ENOG4107RQ2	Cytochrome c oxidase, subunit I
AArcSl_1986	ENOG4105NAA	Cytochrome C oxidase, subunit II
AArcSl_1995	ENOG4105CKK	Glycosyl transferase, family 2
AArcSl_1998	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AArcSl_2001	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AArcSl_2002	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AArcSl_2004	ENOG4105E2A	Dehydrogenase
AArcSl_2008	ENOG4105CHM	Aminotransferase
AArcSl_2014	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AArcSl_2017	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AArcSl_2018	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AArcSl_2021	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AArcSl_2031	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
AArcSl_2032	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
AArcSl_2036	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AArcSl_2037	ENOG4107TH8	cina domain protein
AArcSl_2050	ENOG4108JQ7	(ABC) transporter
AArcSl_2052	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AArcSl_2056	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AArcSl_2058	ENOG4108JQ7	(ABC) transporter
AArcSl_2063	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AArcSl_2066	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AArcSl_2070	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AArcSl_2071	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
AArcSl_2072	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
AArcSl_2084	ENOG4105D7W	serine acetyltransferase
AArcSl_2093	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AArcSl_2094	ENOG410811Q	Ferredoxin
AArcSl_2099	ENOG4107SXA	Phosphorylase
AArcSl_2100	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AArcSl_2101	ENOG4105HDK	L-asparaginase
AArcSl_2102	ENOG4105E0X	reductase
AArcSl_2106	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AArcSl_2114	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AArcSl_2120	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
AArcSl_2122	ENOG4105BZJ	Electron transfer flavoprotein
AArcSl_2123	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AArcSl_2124	ENOG4105CJW	magnesium transporter
AArcSl_2125	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AArcSl_2130	ENOG4105C8J	)-transporter
AArcSl_2134	ENOG4105C6K	Malic enzyme
AArcSl_2137	ENOG4105WKW	Pfam:DUF1458
AArcSl_2138	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AArcSl_2141	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AArcSl_2142	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AArcSl_2144	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AArcSl_2145	ENOG4105C8S	subunit m
AArcSl_2147	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AArcSl_2150	ENOG4108M11	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AArcSl_2151	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AArcSl_2152	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AArcSl_2153	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AArcSl_2154	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AArcSl_2155	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AArcSl_2158	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AArcSl_2159	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AArcSl_2160	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
AArcSl_2161	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AArcSl_2162	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AArcSl_2170	ENOG4105UIB	(ABC) transporter
AArcSl_2171	ENOG4108JQ9	ABC transporter
AArcSl_2172	ENOG4105DIH	basic membrane
AArcSl_2174	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
AArcSl_2176	ENOG4107RUY	(E1 component), alpha subunit
AArcSl_2177	ENOG4105CPP	Dehydrogenase, E1 component
AArcSl_2179	ENOG4105DC7	peptidase M24
AArcSl_2180	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AArcSl_2187	ENOG4105CX6	glutaminyL-tRNA synthetase
AArcSl_2189	ENOG4105D82	Glutamate dehydrogenase
AArcSl_2194	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AArcSl_2196	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AArcSl_2197	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AArcSl_2199	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AArcSl_2200	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AArcSl_2201	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AArcSl_2203	ENOG4105F7N	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
AArcSl_2204	ENOG4105CD3	dihydroorotase
AArcSl_2210	ENOG4105C2I	pirin domain protein
AArcSl_2214	ENOG4105E90	ABC transporter
AArcSl_2216	ENOG4105E90	ABC transporter
AArcSl_2222	ENOG4105J4Q	Transcriptional regulator
AArcSl_2224	ENOG4105CBG	Sulfatase
AArcSl_2225	ENOG4108JB8	alcohol dehydrogenase
AArcSl_2228	ENOG4105C4X	radical SAM domain protein
AArcSl_2240	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AArcSl_2242	ENOG41079K6	HNH endonuclease
AArcSl_2244	ENOG41088T4	Helicase IV
AArcSl_2263	ENOG4108IUW	ABC transporter
AArcSl_2267	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AArcSl_2269	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AArcSl_2274	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AArcSl_2276	ENOG4105CHM	Aminotransferase
AArcSl_2278	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
AArcSl_2281	ENOG4105D1Z	hydroxypyruvate reductase
AArcSl_2290	ENOG4105C0D	helicase
AArcSl_2315	ENOG4107RCC	Major Facilitator Superfamily
AArcSl_2319	ENOG4108R96	Methyltransferase, YaeB family
AArcSl_2320	ENOG4105KNR	Activates the small RNA gene sgrS under glucose- phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain (By similarity)
AArcSl_2321	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AArcSl_2322	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AArcSl_2323	ENOG4105C3U	ABC transporter
AArcSl_2324	ENOG4108JQ7	(ABC) transporter
AArcSl_2325	ENOG4105EIE	fructose-bisphosphate aldolase
AArcSl_2326	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AArcSl_2330	ENOG4105CN9	Peptidase m42 family protein
AArcSl_2331	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AArcSl_2332	ENOG4105EGS	Mechanosensitive ion channel
AArcSl_2334	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AArcSl_2337	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AArcSl_2340	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
AArcSl_2344	ENOG4105DJB	Major Facilitator Superfamily
AArcSl_2352	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AArcSl_2353	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AArcSl_2354	ENOG41080TK	Universal stress protein
AArcSl_2355	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AArcSl_2358	ENOG4105M6F	mutator MutT protein
AArcSl_2361	ENOG4107EFR	Flavocytochrome c
AArcSl_2362	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AArcSl_2372	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AArcSl_2379	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AArcSl_2382	ENOG410908R	Methenyltetrahydrofolate cyclohydrolase
AArcSl_2388	ENOG4108JIG	Anaerobic dehydrogenase
AArcSl_2390	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AArcSl_2391	ENOG4107EUI	c reductase, iron-sulfur
AArcSl_2397	ENOG4107YZX	Universal stress protein
AArcSl_2401	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AArcSl_2402	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AArcSl_2403	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AArcSl_2404	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AArcSl_2405	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AArcSl_2407	ENOG4108VVK	transcriptional Regulator, AsnC
AArcSl_2413	ENOG4107TYC	hydantoinase B oxoprolinase
AArcSl_2417	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
AArcSl_2419	ENOG4107SHJ	sulfite reductase subunit b
AArcSl_2423	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AArcSl_2424	ENOG4105DQU	oxidoreductase, subunit beta
AArcSl_2425	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AArcSl_2427	ENOG4107QF7	multi-drug
AArcSl_2430	ENOG4105C8P	)-transporter
AArcSl_2432	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AArcSl_2433	ENOG4105CUB	amino acid
AArcSl_2434	ENOG4105VF7	tolerance protein
AArcSl_2435	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AArcSl_2437	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AArcSl_2453	ENOG4105DZR	Type I site-specific deoxyribonuclease
AArcSl_2461	ENOG4105BZ1	(ABC) transporter
AArcSl_2462	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
AArcSl_2466	ENOG4107WEA	mandelate racemase muconate lactonizing
AArcSl_2467	ENOG4108UYE	Lactoylglutathione lyase
AArcSl_2476	ENOG4105BZU	Histidine kinase
AArcSl_2477	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AArcSl_2484	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AArcSl_2485	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
AArcSl_2486	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
AArcSl_2487	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
AArcSl_2490	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AArcSl_2491	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AArcSl_2492	ENOG4105C6T	cysteine synthase
AArcSl_2495	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
AArcSl_2496	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
AArcSl_2500	ENOG4105C7W	Xanthine dehydrogenase
AArcSl_2502	ENOG4105CPN	adenine deaminase
AArcSl_2503	ENOG4105C7W	Xanthine dehydrogenase
AArcSl_2508	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AArcSl_2509	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
AArcSl_2510	ENOG4107S4Y	M20 DapE family protein YgeY
AArcSl_2511	ENOG4105C5B	carbamate kinase
AArcSl_2512	ENOG4105DBV	ornithine carbamoyltransferase
AArcSl_2514	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
AArcSl_2516	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AArcSl_2517	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AArcSl_2518	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AArcSl_2520	ENOG4105C8Q	Methyl-accepting chemotaxis
AArcSl_2521	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AArcSl_2522	ENOG4105C7N	Xanthine uracil vitamin C permease
AArcSl_2523	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AArcSl_2524	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
AArcSl_2528	ENOG4105C7B	Threonine dehydratase
AArcSl_2531	ENOG4107RCC	Major Facilitator Superfamily
AArcSl_2532	ENOG4106P37	HTH-type transcriptional regulator YjhI
AArcSl_2535	ENOG4105C3R	Methionine synthase
AArcSl_2537	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AArcSl_2542	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AArcSl_2544	ENOG4107YUH	hydrolase
AArcSl_2546	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AArcSl_2547	ENOG4105E0A	ABC, transporter
AArcSl_2548	ENOG4105EHG	Permease protein
AArcSl_2552	ENOG4105HDK	L-asparaginase
AArcSl_2572	ENOG4105DCI	Phosphohydrolase
AArcSl_2583	ENOG4105CEY	Amp-dependent synthetase and ligase
AArcSl_2592	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
AArcSl_2595	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AArcSl_2596	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AArcSl_2600	ENOG4105CQB	FAD linked oxidase domain protein
AArcSl_2607	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AArcSl_2616	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AArcSl_2618	ENOG4105C8M	UPF0272 protein
AArcSl_2619	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AArcSl_2621	ENOG4105C0H	protease
AArcSl_2627	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AArcSl_2628	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AArcSl_2631	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AArcSl_2632	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AArcSl_2633	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AArcSl_2641	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AArcSl_2642	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AArcSl_2650	ENOG4107VFM	Dehydrogenase
AArcSl_2654	ENOG4105WH1	Two component transcriptional regulator luxr family
AArcSl_2660	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AArcSl_2661	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AArcSl_2662	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AArcSl_2664	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AArcSl_2666	ENOG4105C7K	acetolactate synthase
AArcSl_2667	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AArcSl_2670	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AArcSl_2671	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AArcSl_2675	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AArcSl_2677	ENOG4108JA1	polyketide synthase
AArcSl_2681	ENOG4107QY8	reductase
AArcSl_2682	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AArcSl_2689	ENOG4108RAV	Conserved protein
AArcSl_2696	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AArcSl_2699	ENOG4105CNV	Aldolase
AArcSl_2702	ENOG4105CUB	amino acid
AArcSl_2712	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AArcSl_2715	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AArcSl_2716	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AArcSl_2717	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AArcSl_2719	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AArcSl_2720	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AArcSl_2721	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AArcSl_2726	ENOG4108UJD	30S ribosomal protein S9
AArcSl_2729	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AArcSl_2730	ENOG4105CE9	30S ribosomal protein S2
AArcSl_2731	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AArcSl_2732	ENOG4105CAS	nag kinase
AArcSl_2733	ENOG4105VQD	rieske 2fe-2S domain-containing protein
AArcSl_2734	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AArcSl_2738	ENOG4105C8U	phosphate abc transporter
AArcSl_2739	ENOG4105C8U	phosphate abc transporter
AArcSl_2740	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AArcSl_2745	ENOG4105C01	Dihydroxy-acid dehydratase
AArcSl_2746	ENOG4105ECY	inositol monophosphatase
AArcSl_2747	ENOG4105C5R	Aminotransferase
AArcSl_2750	ENOG4107JTW	chlorite dismutase
AArcSl_2753	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AArcSl_2756	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AArcSl_2757	ENOG4105DVI	reductase, NrfD
AArcSl_2759	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
AArcSl_2760	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AArcSl_2762	ENOG4108S4H	thioesterase Superfamily protein
AArcSl_2786	ENOG4105EWK	phytoene
AArcSl_2789	ENOG4105BZU	Histidine kinase
AArcSl_2792	ENOG4105CGD	Nad-dependent epimerase dehydratase
AArcSl_2794	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
AArcSl_2795	ENOG4105QAX	Iron-sulfur
AArcSl_2798	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AArcSl_2799	ENOG4107QY8	reductase
AArcSl_2800	ENOG4108NEM	leader-binding protein dmsD
AArcSl_2801	ENOG4105C12	Phosphoribosylglycinamide synthetase
AArcSl_2806	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
AArcSl_2807	ENOG4107QKW	extracellular solute-binding protein family 1
AArcSl_2815	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AArcSl_2819	ENOG410811Q	Ferredoxin
AArcSl_2821	ENOG4108U51	Universal stress protein
AArcSl_2826	ENOG4107YZX	Universal stress protein
AArcSl_2830	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AArcSl_2831	ENOG4105C1G	acyl-Coa dehydrogenase
AArcSl_2833	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AArcSl_2834	ENOG4105CXK	mandelate racemase muconate lactonizing
AArcSl_2839	ENOG4105CEP	NADH dehydrogenase
AArcSl_2840	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AArcSl_2843	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
AArcSl_2847	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AArcSl_2848	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AArcSl_2849	ENOG4107SXA	Phosphorylase
AArcSl_2850	ENOG4107SVH	Potassium channel protein
AArcSl_2852	ENOG4105C98	muts2 protein
AArcSl_2857	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AArcSl_2867	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AArcSl_2868	ENOG4105C3G	gtp-binding protein
AArcSl_2872	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AArcSl_2874	ENOG4105CEV	competence damage-inducible protein
AArcSl_2882	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
AArcSl_2889	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AArcSl_2891	ENOG4105KME	endoribonuclease L-psp
AArcSl_2892	ENOG4108R6K	riboflavin synthase, subunit alpha
AArcSl_2896	ENOG4107QI6	Cysteine desulfurase
AArcSl_2898	ENOG4107YZX	Universal stress protein
AArcSl_2900	ENOG4106Z86	ATP-nad acox kinase
AArcSl_2902	ENOG4107RUY	(E1 component), alpha subunit
AArcSl_2903	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AArcSl_2916	ENOG4106BQ7	Glycosyl Transferase
AArcSl_2921	ENOG4105CJR	Integral membrane protein (MviN
AArcSl_2941	ENOG4105BZ1	(ABC) transporter
AArcSl_2942	ENOG4108IAJ	Nad-dependent epimerase dehydratase
AArcSl_2943	ENOG4105D2T	synthase
AArcSl_2944	ENOG4105F0R	Cytidylyltransferase
AArcSl_2956	ENOG4105K64	Glycosyl transferase, family 2
AArcSl_2959	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AArcSl_2960	ENOG4108GH0	ATP-binding protein yghT
AArcSl_2962	ENOG4107UFF	group 1 glycosyl transferase
AArcSl_2982	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AArcSl_2983	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AArcSl_2986	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AArcSl_2987	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AArcSl_2990	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AArcSl_2993	ENOG4106178	UPF0339 protein
AArcSl_3004	ENOG4105Q9Y	Universal stress protein
AArcSl_3011	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
AArcSl_3014	ENOG4108JQ1	Dehydrogenase
AArcSl_3027	ENOG4105D06	uba thif-type nad fad binding protein
AArcSl_3031	ENOG4105MYT	Heat shock protein
AArcSl_3041	ENOG4108MIC	Mg-protoporphyrin IX methyl transferase
AArcSl_3045	ENOG4107TPS	domain protein
AArcSl_3048	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AArcSl_3059	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AArcSl_3061	ENOG41077RS	Phosphatase
AArcSl_3062	ENOG4105CIG	ABC transporter
AArcSl_3063	ENOG4108T0W	nitrous oxide maturation protein NosY
AArcSl_3091	ENOG4105C1A	potassium transporter peripheral membrane
AArcSl_3094	ENOG4107QM5	aconitate hydratase
AArcSl_3096	ENOG4105C22	threonyL-tRNA synthetase
AArcSl_3098	ENOG4108ZAF	Molybdopterin
AArcSl_3099	ENOG4105EYF	MMPL domain protein
AArcSl_3102	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AArcSl_3103	ENOG4105DK7	lysyl-tRNA synthetase
AArcSl_3108	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AArcSl_3111	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AArcSl_3112	ENOG4105E2Z	phosphate ABC transporter (Permease
AArcSl_3113	ENOG4105C8U	phosphate abc transporter
AArcSl_3118	ENOG4108WBT	adenosyltransferase
AArcSl_3125	ENOG4105F7P	transcriptional regulator AsnC family
AArcSl_3126	ENOG4105CHM	Aminotransferase
AArcSl_3127	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AArcSl_3129	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AArcSl_3134	ENOG410905X	membrane-flanked domain protein
AArcSl_3135	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AArcSl_3150	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AArcSl_3157	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AArcSl_3179	ENOG4105D22	carbon starvation protein
AArcSl_3180	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
AArcSl_3183	ENOG4105CKI	cobalamin synthesis protein
AArcSl_3195	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AArcSl_3196	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AArcSl_3198	ENOG4105E4R	Precorrin-3B C17-methyltransferase
AArcSl_3199	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
AArcSl_3200	ENOG4108P62	biosynthesis protein (CbiG)
AArcSl_3202	ENOG4105E4R	Precorrin-3B C17-methyltransferase
AArcSl_3206	ENOG4105CTK	cobaltochelatase, cobn subunit
AArcSl_3208	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AArcSl_3209	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
AArcSl_3210	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AArcSl_3212	ENOG4105D6J	arsenicaL-resistance protein
AArcSl_3216	ENOG4105KWI	UPF0339 protein
AArcSl_3224	ENOG4105CPQ	Dehydrogenase
AArcSl_3232	ENOG4107ZXU	DSBA oxidoreductase
AArcSl_3240	ENOG4105E2R	ROK family
AArcSl_3248	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AArcSl_3249	ENOG4105EMU	Dehydrogenase
AArcSl_3266	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AArcSl_3269	ENOG4105C37	(CBS) domain
AArcSl_3270	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AArcSl_3272	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AArcSl_3279	ENOG4105CDU	Replicative dna helicase
AArcSl_3282	ENOG4105CFH	Aspartokinase
AArcSl_3283	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AArcSl_3285	ENOG41062BK	proline dehydrogenase