locus-tag	class	description
IPF37_00005	COG0772	Belongs to the SEDS family
IPF37_00040	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPF37_00050	COG2385	sporulation resulting in formation of a cellular spore
IPF37_00070	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IPF37_00075	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IPF37_00095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IPF37_00115	COG0233	cytoplasmic translational termination
IPF37_00120	COG0528	UMP kinase activity
IPF37_00130	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IPF37_00135	COG0416	fatty acid biosynthetic process
IPF37_00145	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPF37_00150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IPF37_00160	COG1028	Short-chain dehydrogenase reductase Sdr
IPF37_00165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IPF37_00170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IPF37_00185	COG2827	Endonuclease containing a URI domain
IPF37_00270	COG1968	undecaprenyl-diphosphatase activity
IPF37_00285	COG1674	ftsk spoiiie
IPF37_00290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IPF37_00325	COG4974	Belongs to the 'phage' integrase family
IPF37_00330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IPF37_00340	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPF37_00350	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IPF37_00355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IPF37_00370	COG0126	phosphoglycerate kinase activity
IPF37_00380	COG0698	ribose 5-phosphate isomerase
IPF37_00405	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPF37_00450	COG0359	binds to the 23S rRNA
IPF37_00455	COG0305	Participates in initiation and elongation during chromosome replication
IPF37_00460	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IPF37_00510	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPF37_00520	COG4974	Belongs to the 'phage' integrase family
IPF37_00525	COG0442	prolyl-tRNA aminoacylation
IPF37_00535	COG0194	GDP metabolic process
IPF37_00540	COG0697	spore germination
IPF37_00550	COG1692	metallophosphoesterase
IPF37_00555	COG1418	mRNA catabolic process
IPF37_00575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IPF37_00580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPF37_00585	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IPF37_00630	COG0443	Heat shock 70 kDa protein
IPF37_00640	COG1566	PFAM secretion protein HlyD family protein
IPF37_00645	COG1136	(ABC) transporter
IPF37_00645	COG0577	efflux transmembrane transporter activity
IPF37_00650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IPF37_00655	COG0577	efflux transmembrane transporter activity
IPF37_00655	COG1136	(ABC) transporter
IPF37_00660	COG1136	(ABC) transporter
IPF37_00660	COG0577	efflux transmembrane transporter activity
IPF37_00710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPF37_00720	COG0275	rRNA processing
IPF37_00725	COG2088	sporulation resulting in formation of a cellular spore
IPF37_00740	COG0673	inositol 2-dehydrogenase activity
IPF37_00790	COG0772	Belongs to the SEDS family
IPF37_00795	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPF37_00800	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IPF37_00800	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IPF37_00815	COG1793	dna ligase
IPF37_00820	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IPF37_00830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPF37_00865	COG0789	Transcriptional regulator
IPF37_00870	COG0481	GTPase activity
IPF37_00875	COG0018	arginyl-trna synthetase
IPF37_00885	COG0629	single-stranded DNA binding
IPF37_00915	COG1078	dGTPase activity
IPF37_00925	COG0343	queuine tRNA-ribosyltransferase activity
IPF37_00930	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IPF37_00950	COG0424	maF-like protein
IPF37_00955	COG0758	DNA mediated transformation
IPF37_00960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPF37_01055	COG1561	YicC-like family, N-terminal region
IPF37_01060	COG0217	transcriptional regulatory protein
IPF37_01065	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IPF37_01070	COG1114	Component of the transport system for branched-chain amino acids
IPF37_01090	COG2255	four-way junction helicase activity
IPF37_01120	COG0594	ribonuclease P activity
IPF37_01135	COG0612	Peptidase, M16
IPF37_01140	COG0859	PFAM glycosyl transferase family 9
IPF37_01155	COG0717	Belongs to the dCTP deaminase family
IPF37_01160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPF37_01185	COG0415	Belongs to the DNA photolyase family
IPF37_01220	COG0017	Asparaginyl-tRNA synthetase
IPF37_01240	COG1022	Amp-dependent synthetase and ligase
IPF37_01320	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPF37_01325	COG0037	tRNA processing
IPF37_01350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPF37_01360	COG0484	heat shock protein binding
IPF37_01405	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPF37_01420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IPF37_01435	COG0438	transferase activity, transferring glycosyl groups
IPF37_01440	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPF37_01445	COG0358	DNA primase activity
IPF37_01455	COG0501	Belongs to the peptidase M48B family
IPF37_01465	COG0101	tRNA pseudouridine synthase activity
IPF37_01480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPF37_01500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IPF37_01525	COG1131	(ABC) transporter
IPF37_01545	COG1132	(ABC) transporter
IPF37_01550	COG1881	PFAM PEBP family protein
IPF37_01585	COG0295	cytidine deaminase activity
IPF37_01615	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IPF37_01630	COG4120	Belongs to the binding-protein-dependent transport system permease family
IPF37_01640	COG0484	heat shock protein binding
IPF37_01660	COG0436	Aminotransferase
IPF37_01670	COG0436	Aminotransferase
IPF37_01675	COG1238	metal cluster binding
IPF37_01680	COG0423	glycine-tRNA ligase activity
IPF37_01700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPF37_01705	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPF37_01755	COG0728	peptidoglycan biosynthetic process
IPF37_01760	COG1136	(ABC) transporter
IPF37_01765	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IPF37_01805	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPF37_01810	COG1217	gtp-binding protein TYPA
IPF37_01860	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPF37_01890	COG3655	Transcriptional regulator
IPF37_01910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IPF37_01970	COG0183	Belongs to the thiolase family
IPF37_01990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IPF37_02050	COG0322	excinuclease ABC activity
IPF37_02065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPF37_02075	COG0776	regulation of translation
IPF37_02090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IPF37_02095	COG0012	GTP binding
IPF37_02105	COG0488	(ABC) transporter
IPF37_02115	COG0653	protein targeting
IPF37_02125	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPF37_02235	COG0662	Cupin 2, conserved barrel domain protein
IPF37_02235	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IPF37_02245	COG0367	asparagine synthase
IPF37_02265	COG2154	pterin-4-alpha-carbinolamine dehydratase
IPF37_02280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IPF37_02300	COG0124	histidyl-tRNA synthetase
IPF37_02310	COG0612	Peptidase, M16
IPF37_02330	COG0572	uridine kinase
IPF37_02370	COG0463	Glycosyl transferase, family 2
IPF37_02375	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IPF37_02380	COG0463	Glycosyl transferase, family 2
IPF37_02405	COG2226	methyltransferase
IPF37_02410	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IPF37_02420	COG2226	methyltransferase
IPF37_02440	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPF37_02445	COG0463	Glycosyl transferase, family 2
IPF37_02485	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IPF37_02495	COG0673	inositol 2-dehydrogenase activity
IPF37_02500	COG1083	cytidylyl-transferase
IPF37_02505	COG2089	acid synthase
IPF37_02520	COG1086	Polysaccharide biosynthesis protein
IPF37_02525	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPF37_02540	COG1132	(ABC) transporter
IPF37_02545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IPF37_02550	COG0438	transferase activity, transferring glycosyl groups
IPF37_02615	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPF37_02620	COG1183	phosphatidylcholine synthase activity
IPF37_02630	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IPF37_02665	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPF37_02685	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPF37_02745	COG1459	type II secretion system
IPF37_02765	COG1129	ABC transporter
IPF37_02770	COG4120	Belongs to the binding-protein-dependent transport system permease family
IPF37_02780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IPF37_02855	COG0442	prolyl-tRNA aminoacylation
IPF37_02905	COG0539	negative regulation of cytoplasmic translation
IPF37_02905	COG2183	response to ionizing radiation
IPF37_02930	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IPF37_02935	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPF37_02945	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IPF37_02965	COG0736	holo-[acyl-carrier-protein] synthase activity
IPF37_02970	COG0606	chelatase, subunit chli
IPF37_02980	COG0724	RNA recognition motif
IPF37_03010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPF37_03020	COG1530	ribonuclease E activity
IPF37_03025	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPF37_03040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPF37_03045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPF37_03075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IPF37_03085	COG0495	leucyl-tRNA aminoacylation
IPF37_03130	COG3959	Transketolase, thiamine diphosphate binding domain
IPF37_03165	COG0571	ribonuclease III activity
IPF37_03170	COG0571	ribonuclease III activity
IPF37_03175	COG0556	nucleotide-excision repair
IPF37_03195	COG0187	DNA topoisomerase II activity
IPF37_03215	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IPF37_03225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IPF37_03230	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IPF37_03235	COG1435	thymidine kinase activity
IPF37_03245	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IPF37_03250	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IPF37_03255	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPF37_03300	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
IPF37_03305	COG0250	Participates in transcription elongation, termination and antitermination
IPF37_03310	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPF37_03315	COG0081	regulation of translation
IPF37_03325	COG0222	ribosome binding
IPF37_03330	COG0085	RNA polymerase activity
IPF37_03335	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPF37_03345	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IPF37_03350	COG1185	polyribonucleotide nucleotidyltransferase activity
IPF37_03375	COG1077	Cell shape determining protein MreB Mrl
IPF37_03385	COG0149	triose-phosphate isomerase activity
IPF37_03405	COG2204	response regulator
IPF37_03410	COG0714	Associated with various cellular activities
IPF37_03435	COG1450	Type ii and iii secretion system protein
IPF37_03440	COG1611	Belongs to the LOG family
IPF37_03450	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IPF37_03480	COG0148	phosphopyruvate hydratase activity
IPF37_03505	COG1573	uracil-dna glycosylase
IPF37_03520	COG0195	Participates in both transcription termination and antitermination
IPF37_03525	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPF37_03530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPF37_03535	COG1663	tetraacyldisaccharide 4'-kinase activity
IPF37_03540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPF37_03545	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
IPF37_03550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPF37_03565	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPF37_03570	COG0459	protein refolding
IPF37_03580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPF37_03580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPF37_03585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IPF37_03600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IPF37_03605	COG0729	surface antigen
IPF37_03625	COG0356	it plays a direct role in the translocation of protons across the membrane
IPF37_03650	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IPF37_03675	COG0668	transmembrane transport
IPF37_03720	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPF37_03725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IPF37_03735	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IPF37_03750	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
IPF37_03785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IPF37_03790	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IPF37_03820	COG1115	amino acid carrier protein
IPF37_03840	COG1994	Peptidase M50
IPF37_03860	COG2222	sugar isomerase
IPF37_03865	COG0254	rRNA binding
IPF37_03870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPF37_03875	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IPF37_03885	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
IPF37_03920	COG3842	ATPase activity
IPF37_03925	COG1176	ABC-type spermidine putrescine transport system, permease component I
IPF37_03930	COG1177	transmembrane transport
IPF37_03940	COG0681	Belongs to the peptidase S26 family
IPF37_03945	COG0681	Belongs to the peptidase S26 family
IPF37_03950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPF37_03950	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPF37_04010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IPF37_04025	COG0668	transmembrane transport
IPF37_04035	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IPF37_04050	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IPF37_04055	COG0525	valine-tRNA ligase activity
IPF37_04080	COG0513	Belongs to the DEAD box helicase family
IPF37_04095	COG1126	abc transporter atp-binding protein
IPF37_04100	COG0765	amino acid transport
IPF37_04180	COG2239	Acts as a magnesium transporter
IPF37_04185	COG0564	pseudouridine synthase activity
IPF37_04200	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IPF37_04210	COG0511	ligase activity, forming carbon-carbon bonds
IPF37_04215	COG0439	Biotin carboxylase
IPF37_04240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPF37_04245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IPF37_04250	COG0822	iron-sulfur transferase activity
IPF37_04255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IPF37_04305	COG1671	Belongs to the UPF0178 family
IPF37_04345	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IPF37_04380	COG0300	oxidoreductase activity
IPF37_04400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IPF37_04415	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPF37_04415	COG0072	phenylalanine-tRNA ligase activity
IPF37_04420	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IPF37_04430	COG1040	competence protein
IPF37_04445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPF37_04450	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPF37_04455	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IPF37_04465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPF37_04470	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IPF37_04480	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPF37_04525	COG1253	flavin adenine dinucleotide binding
IPF37_04530	COG1132	(ABC) transporter
IPF37_04535	COG0488	(ABC) transporter
IPF37_04600	COG0396	ATPase activity
IPF37_04625	COG4968	Prepilin-type N-terminal cleavage methylation domain
IPF37_04630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IPF37_04635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IPF37_04635	COG0517	IMP dehydrogenase activity
IPF37_04645	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IPF37_04655	COG0445	tRNA wobble uridine modification
IPF37_04715	COG0719	Fe-S assembly protein
IPF37_04720	COG1496	oxidoreductase activity
IPF37_04725	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPF37_04745	COG3118	belongs to the thioredoxin family
IPF37_04745	COG0492	ferredoxin-NADP+ reductase activity
IPF37_04775	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IPF37_04780	COG0501	Belongs to the peptidase M48B family
IPF37_04790	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPF37_04800	COG0552	protein localization to endoplasmic reticulum
IPF37_04810	COG2890	protein-(glutamine-N5) methyltransferase activity
IPF37_04820	COG0616	signal peptide processing
IPF37_04825	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IPF37_04825	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IPF37_04830	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IPF37_04880	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IPF37_04890	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IPF37_04895	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPF37_04900	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IPF37_04905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPF37_04905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPF37_04915	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPF37_04930	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
IPF37_04935	COG0446	pyridine nucleotide-disulphide oxidoreductase
IPF37_04940	COG1355	regulation of microtubule-based process
IPF37_04950	COG3118	belongs to the thioredoxin family
IPF37_04960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IPF37_04965	COG0436	Aminotransferase
IPF37_04980	COG0617	tRNA 3'-terminal CCA addition
IPF37_04990	COG0268	Binds directly to 16S ribosomal RNA
IPF37_04995	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IPF37_05000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPF37_05005	COG0823	Involved in the tonB-independent uptake of proteins
IPF37_05020	COG0811	peptide transport
IPF37_05095	COG5000	phosphorelay sensor kinase activity
IPF37_05110	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPF37_05120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IPF37_05130	COG0285	dihydrofolate synthase activity
IPF37_05200	COG0492	ferredoxin-NADP+ reductase activity
IPF37_05205	COG0450	alkyl hydroperoxide reductase
IPF37_05230	COG0537	adenosine 5'-monophosphoramidase activity
IPF37_05240	COG1459	type II secretion system
IPF37_05250	COG1872	DUF167
IPF37_05280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IPF37_05300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPF37_05355	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPF37_05375	COG0336	Belongs to the RNA methyltransferase TrmD family
IPF37_05380	COG1837	Belongs to the UPF0109 family
IPF37_05385	COG0228	four-way junction DNA binding
IPF37_05390	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IPF37_05410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IPF37_05415	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IPF37_05420	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IPF37_05425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IPF37_05465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPF37_05475	COG1187	pseudouridine synthase activity
IPF37_05525	COG0688	phosphatidylethanolamine metabolic process
IPF37_05530	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IPF37_05560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPF37_05580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IPF37_05600	COG0215	cysteine-tRNA ligase activity
IPF37_05620	COG0792	nuclease activity
IPF37_05630	COG0706	membrane insertase activity
IPF37_05635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IPF37_05645	COG0006	proline dipeptidase activity
IPF37_05650	COG0504	CTP synthase activity
IPF37_05655	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IPF37_05660	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IPF37_05670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IPF37_05675	COG0049	tRNA binding
IPF37_05680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IPF37_05685	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IPF37_05690	COG0051	transcription antitermination factor activity, RNA binding
IPF37_05695	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPF37_05700	COG0088	Forms part of the polypeptide exit tunnel
IPF37_05705	COG0089	rRNA binding
IPF37_05710	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IPF37_05715	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPF37_05720	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPF37_05725	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPF37_05730	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPF37_05740	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IPF37_05745	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IPF37_05750	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPF37_05755	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IPF37_05765	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPF37_05770	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IPF37_05780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPF37_05785	COG0200	Binds to the 23S rRNA
IPF37_05790	COG0201	protein transport
IPF37_05795	COG0563	adenylate kinase activity
IPF37_05805	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPF37_05810	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IPF37_05820	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPF37_05825	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPF37_05830	COG0202	RNA polymerase activity
IPF37_05835	COG0203	ribosomal protein L17
IPF37_05840	COG0039	L-malate dehydrogenase activity
IPF37_06010	COG2255	four-way junction helicase activity
IPF37_06025	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPF37_06055	COG3070	regulator of competence-specific genes
IPF37_06065	COG2255	four-way junction helicase activity
IPF37_06105	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IPF37_06105	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IPF37_06110	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IPF37_06120	COG1660	Displays ATPase and GTPase activities
IPF37_06125	COG0793	Belongs to the peptidase S41A family
IPF37_06135	COG1519	Transferase
IPF37_06155	COG0513	Belongs to the DEAD box helicase family
IPF37_06175	COG0768	penicillin binding
IPF37_06180	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IPF37_06220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IPF37_06225	COG0154	amidase activity
IPF37_06230	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPF37_06240	COG0534	Mate efflux family protein
IPF37_06330	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
IPF37_06350	COG1137	ATPase activity
IPF37_06355	COG1160	GTP binding
IPF37_06480	COG0666	response to abiotic stimulus
IPF37_06635	COG0666	response to abiotic stimulus
IPF37_06640	COG3293	Transposase
IPF37_06770	COG0419	ATPase involved in DNA repair
IPF37_06770	COG0419	ATPase involved in DNA repair