locus-tag	class	description
IPG36_00050	COG0463	Glycosyl transferase, family 2
IPG36_00175	COG1695	Transcriptional regulator
IPG36_00180	COG0745	RESPONSE REGULATOR receiver
IPG36_00185	COG5002	protein histidine kinase activity
IPG36_00225	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IPG36_00230	COG1271	oxidase subunit
IPG36_00250	COG0167	dihydroorotate dehydrogenase activity
IPG36_00285	COG0724	RNA recognition motif
IPG36_00290	COG2135	peptidase activity
IPG36_00295	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IPG36_00395	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IPG36_00400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IPG36_00440	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IPG36_00445	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IPG36_00450	COG0492	ferredoxin-NADP+ reductase activity
IPG36_00460	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
IPG36_00470	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
IPG36_00490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IPG36_00495	COG0477	Major facilitator Superfamily
IPG36_00500	COG0477	Major facilitator Superfamily
IPG36_00575	COG1692	metallophosphoesterase
IPG36_00590	COG1418	mRNA catabolic process
IPG36_00630	COG1459	type II secretion system
IPG36_00710	COG0632	four-way junction helicase activity
IPG36_00715	COG0297	glycogen (starch) synthase activity
IPG36_00740	COG0058	SHG alpha-glucan phosphorylase activity
IPG36_00745	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IPG36_00810	COG0217	transcriptional regulatory protein
IPG36_00835	COG2321	neutral zinc metallopeptidase
IPG36_00920	COG0443	Heat shock 70 kDa protein
IPG36_01020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPG36_01025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IPG36_01030	COG1420	regulation of RNA biosynthetic process
IPG36_01055	COG0481	GTPase activity
IPG36_01060	COG1181	Belongs to the D-alanine--D-alanine ligase family
IPG36_01065	COG2890	protein-(glutamine-N5) methyltransferase activity
IPG36_01070	COG0728	peptidoglycan biosynthetic process
IPG36_01080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IPG36_01085	COG0037	tRNA processing
IPG36_01135	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IPG36_01135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IPG36_01150	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IPG36_01165	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPG36_01170	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPG36_01175	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPG36_01200	COG0724	RNA recognition motif
IPG36_01220	COG0281	malic enzyme
IPG36_01230	COG2205	protein histidine kinase activity
IPG36_01240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IPG36_01245	COG2133	pyrroloquinoline quinone binding
IPG36_01320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IPG36_01345	COG1131	(ABC) transporter
IPG36_01375	COG0577	efflux transmembrane transporter activity
IPG36_01380	COG1136	(ABC) transporter
IPG36_01435	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IPG36_01440	COG2720	vancomycin resistance protein
IPG36_01455	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IPG36_01455	COG0662	Cupin 2, conserved barrel domain protein
IPG36_01460	COG0662	Cupin 2, conserved barrel domain protein
IPG36_01460	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
IPG36_01655	COG0438	transferase activity, transferring glycosyl groups
IPG36_01665	COG0297	glycogen (starch) synthase activity
IPG36_01705	COG0706	membrane insertase activity
IPG36_01710	COG0594	ribonuclease P activity
IPG36_01715	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IPG36_01820	COG0616	signal peptide processing
IPG36_01825	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IPG36_01850	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IPG36_01955	COG0071	Belongs to the small heat shock protein (HSP20) family
IPG36_01960	COG1040	competence protein
IPG36_02050	COG1215	transferase activity, transferring glycosyl groups
IPG36_02080	COG0525	valine-tRNA ligase activity
IPG36_02085	COG0525	valine-tRNA ligase activity
IPG36_02095	COG0525	valine-tRNA ligase activity
IPG36_02125	COG0009	L-threonylcarbamoyladenylate synthase
IPG36_02135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IPG36_02185	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPG36_02200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IPG36_02245	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPG36_02250	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IPG36_02260	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IPG36_02290	COG2222	sugar isomerase
IPG36_02295	COG1136	(ABC) transporter
IPG36_02295	COG0577	efflux transmembrane transporter activity
IPG36_02330	COG0754	glutathionylspermidine amidase activity
IPG36_02385	COG0358	DNA primase activity
IPG36_02420	COG1278	Cold shock
IPG36_02435	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IPG36_02440	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IPG36_02460	COG1121	(ABC) transporter
IPG36_02465	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IPG36_02470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPG36_02470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IPG36_02480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IPG36_02485	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IPG36_02515	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IPG36_02540	COG1573	uracil-dna glycosylase
IPG36_02545	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IPG36_02550	COG0494	nUDIX hydrolase
IPG36_02555	COG1051	belongs to the nudix hydrolase family
IPG36_02560	COG1132	(ABC) transporter
IPG36_02575	COG1674	ftsk spoiiie
IPG36_02575	COG4980	gas vesicle protein
IPG36_02580	COG3177	Filamentation induced by cAMP protein fic
IPG36_02595	COG1666	GTP binding
IPG36_02615	COG0360	Binds together with S18 to 16S ribosomal RNA
IPG36_02625	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IPG36_02630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IPG36_02635	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IPG36_02640	COG0012	GTP binding
IPG36_02705	COG1459	type II secretion system
IPG36_02725	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IPG36_02770	COG0586	Pfam SNARE associated Golgi protein
IPG36_02780	COG0612	Peptidase, M16
IPG36_02785	COG0105	UTP biosynthetic process
IPG36_02800	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IPG36_02850	COG0242	peptide deformylase activity
IPG36_02900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPG36_02910	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IPG36_02935	COG3835	regulator
IPG36_02940	COG2508	Transcriptional regulator
IPG36_02960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPG36_02965	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IPG36_02970	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IPG36_02975	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IPG36_03010	COG1994	Peptidase M50
IPG36_03045	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IPG36_03060	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IPG36_03065	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IPG36_03085	COG0606	chelatase, subunit chli
IPG36_03090	COG0606	chelatase, subunit chli
IPG36_03125	COG0516	GMP reductase activity
IPG36_03125	COG0517	IMP dehydrogenase activity
IPG36_03130	COG1316	TRANSCRIPTIONal
IPG36_03145	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IPG36_03150	COG1928	C-terminal four TMM region of protein-O-mannosyltransferase
IPG36_03160	COG3942	CHAP domain
IPG36_03180	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IPG36_03185	COG0018	arginyl-trna synthetase
IPG36_03250	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IPG36_03255	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPG36_03255	COG0072	phenylalanine-tRNA ligase activity
IPG36_03260	COG0072	phenylalanine-tRNA ligase activity
IPG36_03260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPG36_03300	COG0187	DNA topoisomerase II activity
IPG36_03305	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IPG36_03435	COG0539	negative regulation of cytoplasmic translation
IPG36_03445	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IPG36_03485	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IPG36_03490	COG0242	peptide deformylase activity
IPG36_03495	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPG36_03500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IPG36_03510	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPG36_03515	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IPG36_03525	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IPG36_03525	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IPG36_03530	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IPG36_03560	COG0563	adenylate kinase activity
IPG36_03565	COG0024	Methionine aminopeptidase
IPG36_03580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IPG36_03590	COG0762	integral membrane protein
IPG36_03595	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPG36_03605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPG36_03610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IPG36_03615	COG0772	Belongs to the SEDS family
IPG36_03620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IPG36_03765	COG1192	Involved in chromosome partitioning
IPG36_03770	COG1475	DNA binding
IPG36_03785	COG1316	TRANSCRIPTIONal
IPG36_03795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPG36_03800	COG2890	protein-(glutamine-N5) methyltransferase activity
IPG36_03810	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IPG36_03825	COG0254	rRNA binding
IPG36_03835	COG0052	Belongs to the universal ribosomal protein uS2 family
IPG36_03840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IPG36_03845	COG0233	cytoplasmic translational termination
IPG36_03850	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IPG36_03855	COG0750	zinc metalloprotease
IPG36_03865	COG0442	prolyl-tRNA aminoacylation
IPG36_03885	COG1077	Cell shape determining protein MreB Mrl
IPG36_03905	COG0768	penicillin binding
IPG36_03910	COG0768	penicillin binding
IPG36_03915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IPG36_03920	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
IPG36_03930	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IPG36_03935	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
IPG36_03940	COG0653	protein targeting
IPG36_03945	COG0653	protein targeting
IPG36_03950	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IPG36_03955	COG1365	unkown
IPG36_03970	COG2001	Belongs to the MraZ family
IPG36_03975	COG0275	rRNA processing
IPG36_03990	COG0768	penicillin binding
IPG36_03995	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IPG36_04000	COG0772	Belongs to the SEDS family
IPG36_04040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IPG36_04045	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IPG36_04050	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IPG36_04060	COG1381	Involved in DNA repair and RecF pathway recombination
IPG36_04065	COG0745	RESPONSE REGULATOR receiver
IPG36_04070	COG5002	protein histidine kinase activity
IPG36_04075	COG5002	protein histidine kinase activity
IPG36_04085	COG2264	protein methyltransferase activity
IPG36_04090	COG1722	exodeoxyribonuclease VII activity
IPG36_04095	COG1570	exodeoxyribonuclease VII activity
IPG36_04105	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IPG36_04110	COG0504	CTP synthase activity
IPG36_04125	COG3409	Peptidoglycan-binding domain 1 protein
IPG36_04125	COG0793	Belongs to the peptidase S41A family
IPG36_04135	COG2177	Part of the ABC transporter FtsEX involved in
IPG36_04140	COG2884	Cell division ATP-binding protein ftsE
IPG36_04145	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IPG36_04165	COG0513	Belongs to the DEAD box helicase family
IPG36_04185	COG1028	Short-chain dehydrogenase reductase Sdr
IPG36_04200	COG0758	DNA mediated transformation
IPG36_04215	COG1160	GTP binding
IPG36_04220	COG1686	Belongs to the peptidase S11 family
IPG36_04225	COG1187	pseudouridine synthase activity
IPG36_04230	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IPG36_04240	COG0745	RESPONSE REGULATOR receiver
IPG36_04245	COG5002	protein histidine kinase activity
IPG36_04270	COG1388	LysM domain
IPG36_04275	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
IPG36_04275	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IPG36_04310	COG0438	transferase activity, transferring glycosyl groups
IPG36_04315	COG0438	transferase activity, transferring glycosyl groups
IPG36_04340	COG0745	RESPONSE REGULATOR receiver
IPG36_04345	COG2205	protein histidine kinase activity
IPG36_04355	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
IPG36_04360	COG1470	cell adhesion involved in biofilm formation
IPG36_04375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IPG36_04385	COG0151	Belongs to the GarS family
IPG36_04410	COG1077	Cell shape determining protein MreB Mrl
IPG36_04485	COG1215	transferase activity, transferring glycosyl groups
IPG36_04565	COG0577	efflux transmembrane transporter activity
IPG36_04570	COG1136	(ABC) transporter
IPG36_04580	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IPG36_04590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IPG36_04605	COG1525	nuclease
IPG36_04625	COG0588	phosphoglycerate mutase activity
IPG36_04630	COG0588	phosphoglycerate mutase activity
IPG36_04660	COG1477	protein flavinylation
IPG36_04695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IPG36_04705	COG0492	ferredoxin-NADP+ reductase activity
IPG36_04720	COG0500	methyltransferase
IPG36_04740	COG1846	Transcriptional regulator
IPG36_04745	COG0494	nUDIX hydrolase
IPG36_04780	COG0242	peptide deformylase activity
IPG36_04855	COG1132	(ABC) transporter
IPG36_04860	COG1132	(ABC) transporter
IPG36_04890	COG5002	protein histidine kinase activity
IPG36_04905	COG0215	cysteine-tRNA ligase activity
IPG36_04910	COG0215	cysteine-tRNA ligase activity
IPG36_04915	COG0215	cysteine-tRNA ligase activity
IPG36_04940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IPG36_04985	COG0305	Participates in initiation and elongation during chromosome replication
IPG36_04995	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IPG36_05030	COG0222	ribosome binding
IPG36_05035	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPG36_05040	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IPG36_05060	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IPG36_05090	COG0081	regulation of translation
IPG36_05095	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IPG36_05105	COG0250	Participates in transcription elongation, termination and antitermination
IPG36_05125	COG1217	gtp-binding protein TYPA
IPG36_05130	COG0017	Asparaginyl-tRNA synthetase
IPG36_05145	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IPG36_05180	COG5297	Belongs to the glycosyl hydrolase family 6
IPG36_05185	COG0577	efflux transmembrane transporter activity
IPG36_05185	COG1136	(ABC) transporter
IPG36_05190	COG1136	(ABC) transporter
IPG36_05235	COG2202	Pas domain
IPG36_05235	COG2205	protein histidine kinase activity
IPG36_05275	COG5183	chlorophyll binding
IPG36_05275	COG2133	pyrroloquinoline quinone binding
IPG36_05280	COG1396	sequence-specific DNA binding
IPG36_05310	COG3942	CHAP domain
IPG36_05330	COG2135	peptidase activity
IPG36_05420	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IPG36_05480	COG0564	pseudouridine synthase activity
IPG36_05510	COG0203	ribosomal protein L17
IPG36_05515	COG0202	RNA polymerase activity
IPG36_05520	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IPG36_05525	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IPG36_05535	COG0257	Belongs to the bacterial ribosomal protein bL36 family
IPG36_05540	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
IPG36_05555	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IPG36_05560	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IPG36_05570	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IPG36_05575	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IPG36_05585	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IPG36_05605	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IPG36_05610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IPG36_05615	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IPG36_05620	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IPG36_05630	COG0089	rRNA binding
IPG36_05640	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IPG36_05715	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IPG36_05720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IPG36_05730	COG0488	(ABC) transporter
IPG36_05735	COG0488	(ABC) transporter
IPG36_05760	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPG36_05765	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPG36_05770	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IPG36_05775	COG0085	RNA polymerase activity
IPG36_05795	COG2814	Major facilitator Superfamily
IPG36_05800	COG0740	serine-type endopeptidase activity
IPG36_05805	COG0544	peptidyl-prolyl cis-trans isomerase activity
IPG36_05810	COG0544	peptidyl-prolyl cis-trans isomerase activity
IPG36_05935	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IPG36_05940	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IPG36_05950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IPG36_05990	COG4956	integral membrane protein (PIN domain superfamily)
IPG36_05995	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IPG36_06000	COG0542	response to heat
IPG36_06020	COG0308	aminopeptidase N
IPG36_06025	COG0792	nuclease activity
IPG36_06030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IPG36_06085	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPG36_06105	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IPG36_06210	COG0543	2 iron, 2 sulfur cluster binding
IPG36_06210	COG0633	Ferredoxin
IPG36_06240	COG2925	Exonuclease
IPG36_06295	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
IPG36_06320	COG3645	SOS response
IPG36_06340	COG3586	endonuclease activity
IPG36_06350	COG3177	Filamentation induced by cAMP protein fic
IPG36_06485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IPG36_06510	COG0501	Belongs to the peptidase M48B family
IPG36_06550	COG0543	2 iron, 2 sulfur cluster binding
IPG36_06575	COG0330	HflC and HflK could
IPG36_06625	COG3437	response regulator, receiver
IPG36_06625	COG2205	protein histidine kinase activity
IPG36_06625	COG3850	Histidine kinase
IPG36_06625	COG4999	Histidine kinase
IPG36_06645	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IPG36_06660	COG0745	RESPONSE REGULATOR receiver
IPG36_06835	COG2169	Transcriptional regulator
IPG36_06835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IPG36_06860	COG2003	Belongs to the UPF0758 family
IPG36_06920	COG0277	FAD linked oxidase domain protein
IPG36_07010	COG0747	negative chemotaxis
IPG36_07020	COG1950	PFAM Membrane protein of
IPG36_07025	COG0006	proline dipeptidase activity
IPG36_07030	COG0640	Transcriptional regulator
IPG36_07035	COG0322	excinuclease ABC activity
IPG36_07040	COG0322	excinuclease ABC activity
IPG36_07065	COG1215	transferase activity, transferring glycosyl groups
IPG36_07090	COG0438	transferase activity, transferring glycosyl groups
IPG36_07130	COG0556	nucleotide-excision repair
IPG36_07145	COG2340	Cysteine-rich secretory protein family
IPG36_07180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IPG36_07215	COG0726	polysaccharide deacetylase
IPG36_07225	COG1215	transferase activity, transferring glycosyl groups
IPG36_07240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IPG36_07245	COG0698	ribose 5-phosphate isomerase
IPG36_07250	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IPG36_07280	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IPG36_07285	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IPG36_07290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IPG36_07340	COG0363	glucosamine-6-phosphate deaminase activity
IPG36_07380	COG0356	it plays a direct role in the translocation of protons across the membrane
IPG36_07385	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPG36_07390	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IPG36_07400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IPG36_07405	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IPG36_07410	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IPG36_07420	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IPG36_07430	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IPG36_07505	COG0277	FAD linked oxidase domain protein
IPG36_07505	COG0247	lactate metabolic process
IPG36_07535	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
IPG36_07550	COG2261	transglycosylase associated protein
IPG36_07565	COG0745	RESPONSE REGULATOR receiver
IPG36_07575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IPG36_07585	COG1131	(ABC) transporter
IPG36_07590	COG1131	(ABC) transporter
IPG36_07595	COG5002	protein histidine kinase activity
IPG36_07615	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IPG36_07675	COG0336	Belongs to the RNA methyltransferase TrmD family
IPG36_07680	COG1837	Belongs to the UPF0109 family
IPG36_07685	COG0228	four-way junction DNA binding
IPG36_07690	COG1196	nuclear chromosome segregation
IPG36_07690	COG1196	nuclear chromosome segregation
IPG36_07700	COG0571	ribonuclease III activity
IPG36_07730	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
IPG36_07735	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
IPG36_07760	COG0463	Glycosyl transferase, family 2
IPG36_07765	COG0484	heat shock protein binding
IPG36_07770	COG0495	leucyl-tRNA aminoacylation
IPG36_07775	COG0495	leucyl-tRNA aminoacylation
IPG36_07795	COG0756	dUTP diphosphatase activity
IPG36_07800	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IPG36_07845	COG2409	Drug exporters of the RND superfamily
IPG36_07915	COG1132	(ABC) transporter
IPG36_07945	COG3942	CHAP domain
IPG36_07945	COG1388	LysM domain
IPG36_07950	COG1388	LysM domain
IPG36_07950	COG0741	lytic transglycosylase activity
IPG36_07960	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IPG36_08015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IPG36_08045	COG1104	cysteine desulfurase activity
IPG36_08050	COG0084	hydrolase, TatD family'
IPG36_08055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPG36_08055	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPG36_08060	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IPG36_08070	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IPG36_08080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IPG36_08100	COG0528	UMP kinase activity
IPG36_08125	COG0210	DNA helicase
IPG36_08145	COG0149	triose-phosphate isomerase activity
IPG36_08150	COG0149	triose-phosphate isomerase activity
IPG36_08175	COG0126	phosphoglycerate kinase activity
IPG36_08180	COG0126	phosphoglycerate kinase activity
IPG36_08265	COG1216	Glycosyl transferase, family 2