locus-tag	class	description
KFE94_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFE94_00045	COG0514	ATP-dependent DNA helicase (RecQ)
KFE94_00055	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFE94_00060	COG0315	cyclic pyranopterin monophosphate synthase activity
KFE94_00080	COG0746	molybdenum cofactor guanylyltransferase activity
KFE94_00105	COG0437	4 iron, 4 sulfur cluster binding
KFE94_00120	COG0243	molybdopterin cofactor binding
KFE94_00140	COG0629	single-stranded DNA binding
KFE94_00205	COG2827	Endonuclease containing a URI domain
KFE94_00210	COG2827	Endonuclease containing a URI domain
KFE94_00255	COG1733	regulation of RNA biosynthetic process
KFE94_00285	COG2205	protein histidine kinase activity
KFE94_00285	COG3292	Two component regulator propeller
KFE94_00285	COG0745	RESPONSE REGULATOR receiver
KFE94_00290	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KFE94_00300	COG2827	Endonuclease containing a URI domain
KFE94_00305	COG2827	Endonuclease containing a URI domain
KFE94_00310	COG2827	Endonuclease containing a URI domain
KFE94_00315	COG2827	Endonuclease containing a URI domain
KFE94_00340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFE94_00345	COG1132	(ABC) transporter
KFE94_00350	COG4953	penicillin-binding protein 1C
KFE94_00355	COG2373	Large extracellular alpha-helical protein
KFE94_00360	COG4771	TonB-dependent receptor
KFE94_00420	COG1858	cytochrome C peroxidase
KFE94_00435	COG0330	HflC and HflK could
KFE94_00440	COG0330	HflC and HflK could
KFE94_00445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFE94_00450	COG0513	Belongs to the DEAD box helicase family
KFE94_00515	COG0228	four-way junction DNA binding
KFE94_00520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFE94_00550	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
KFE94_00555	COG0308	aminopeptidase N
KFE94_00560	COG1132	(ABC) transporter
KFE94_00605	COG3813	Protein conserved in bacteria
KFE94_00615	COG0471	metal ion transport
KFE94_00650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFE94_00680	COG1032	radical SAM domain protein
KFE94_00720	COG0668	transmembrane transport
KFE94_00725	COG0512	Glutamine amidotransferase of anthranilate synthase
KFE94_00755	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KFE94_00765	COG2195	Cleaves the N-terminal amino acid of tripeptides
KFE94_00840	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KFE94_00855	COG0513	Belongs to the DEAD box helicase family
KFE94_00880	COG1333	cytochrome c biogenesis protein
KFE94_00880	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KFE94_00885	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
KFE94_00890	COG3005	denitrification pathway
KFE94_00900	COG2356	endonuclease I
KFE94_00915	COG2095	MarC family integral membrane protein
KFE94_00920	COG3275	phosphorelay sensor kinase activity
KFE94_00925	COG3275	phosphorelay sensor kinase activity
KFE94_00935	COG0659	secondary active sulfate transmembrane transporter activity
KFE94_00940	COG0105	UTP biosynthetic process
KFE94_00960	COG0741	lytic transglycosylase activity
KFE94_00960	COG1388	LysM domain
KFE94_00990	COG0572	uridine kinase
KFE94_00995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFE94_01000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFE94_01015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KFE94_01020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFE94_01025	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KFE94_01030	COG2171	N-acyltransferase activity
KFE94_01035	COG0859	PFAM glycosyl transferase family 9
KFE94_01075	COG3278	Belongs to the heme-copper respiratory oxidase family
KFE94_01085	COG2217	Heavy metal translocating P-type atpase
KFE94_01095	COG0514	ATP-dependent DNA helicase (RecQ)
KFE94_01100	COG2205	protein histidine kinase activity
KFE94_01100	COG0784	Response regulator, receiver
KFE94_01115	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFE94_01125	COG0116	Belongs to the methyltransferase superfamily
KFE94_01125	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFE94_01135	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KFE94_01145	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KFE94_01165	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFE94_01170	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KFE94_01175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFE94_01175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KFE94_01180	COG0167	dihydroorotate dehydrogenase activity
KFE94_01190	COG2264	protein methyltransferase activity
KFE94_01205	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KFE94_01220	COG1674	ftsk spoiiie
KFE94_01230	COG4895	conserved protein (DUF2196)
KFE94_01270	COG3275	phosphorelay sensor kinase activity
KFE94_01275	COG2204	response regulator
KFE94_01330	COG3279	Response regulator of the LytR AlgR family
KFE94_01350	COG2326	polyphosphate kinase activity
KFE94_01410	COG2996	Protein conserved in bacteria
KFE94_01415	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KFE94_01445	COG0542	response to heat
KFE94_01490	COG1716	ATPase activity
KFE94_01490	COG1131	(ABC) transporter
KFE94_01490	COG0842	Transport permease protein
KFE94_01545	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFE94_01570	COG0745	RESPONSE REGULATOR receiver
KFE94_01585	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KFE94_01605	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
KFE94_01630	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFE94_01635	COG0739	heme binding
KFE94_01635	COG0741	lytic transglycosylase activity
KFE94_01635	COG1196	nuclear chromosome segregation
KFE94_01670	COG1858	cytochrome C peroxidase
KFE94_01675	COG1278	Cold shock
KFE94_01705	COG0436	Aminotransferase
KFE94_01710	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KFE94_01710	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KFE94_01720	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFE94_01775	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFE94_01780	COG1404	Belongs to the peptidase S8 family
KFE94_01790	COG1216	Glycosyl transferase, family 2
KFE94_01795	COG0463	Glycosyl transferase, family 2
KFE94_01815	COG0708	Exodeoxyribonuclease III
KFE94_01825	COG1858	cytochrome C peroxidase
KFE94_01830	COG1979	alcohol dehydrogenase
KFE94_01840	COG0716	FMN binding
KFE94_01855	COG0302	gtp cyclohydrolase
KFE94_01870	COG0045	succinate-CoA ligase (ADP-forming) activity
KFE94_01875	COG1136	(ABC) transporter
KFE94_01890	COG1733	regulation of RNA biosynthetic process
KFE94_02005	COG0492	ferredoxin-NADP+ reductase activity
KFE94_02015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFE94_02035	COG0714	Associated with various cellular activities
KFE94_02050	COG2304	oxidoreductase activity
KFE94_02055	COG2304	oxidoreductase activity
KFE94_02080	COG0501	Belongs to the peptidase M48B family
KFE94_02175	COG0569	domain protein
KFE94_02180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFE94_02185	COG0791	NLP P60 protein
KFE94_02190	COG0183	Belongs to the thiolase family
KFE94_02195	COG2205	protein histidine kinase activity
KFE94_02195	COG0784	Response regulator, receiver
KFE94_02215	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFE94_02240	COG2181	nitrate reductase activity
KFE94_02240	COG0247	lactate metabolic process
KFE94_02245	COG2181	nitrate reductase activity
KFE94_02245	COG0247	lactate metabolic process
KFE94_02255	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFE94_02265	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFE94_02275	COG5002	protein histidine kinase activity
KFE94_02280	COG0745	RESPONSE REGULATOR receiver
KFE94_02290	COG0393	Putative heavy-metal-binding
KFE94_02345	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFE94_02355	COG0488	(ABC) transporter
KFE94_02365	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KFE94_02380	COG1999	signal sequence binding
KFE94_02505	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KFE94_02510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KFE94_02525	COG3275	phosphorelay sensor kinase activity
KFE94_02530	COG3279	Response regulator of the LytR AlgR family
KFE94_02535	COG0488	(ABC) transporter
KFE94_02565	COG0823	Involved in the tonB-independent uptake of proteins
KFE94_02565	COG1506	peptidase
KFE94_02570	COG3104	oligopeptide transport
KFE94_02585	COG4206	TonB-dependent receptor
KFE94_02590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFE94_02595	COG0156	8-amino-7-oxononanoate synthase activity
KFE94_02600	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
KFE94_02615	COG3339	Conserved Protein
KFE94_02625	COG2884	Cell division ATP-binding protein ftsE
KFE94_02640	COG0187	DNA topoisomerase II activity
KFE94_02655	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KFE94_02655	COG1333	cytochrome c biogenesis protein
KFE94_02660	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFE94_02665	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KFE94_02675	COG0424	maF-like protein
KFE94_02710	COG0545	Peptidyl-prolyl cis-trans isomerase
KFE94_02720	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KFE94_02770	COG0513	Belongs to the DEAD box helicase family
KFE94_02775	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KFE94_02780	COG1607	acyl-coa hydrolase
KFE94_02785	COG2608	mercury ion transmembrane transporter activity
KFE94_02800	COG0101	tRNA pseudouridine synthase activity
KFE94_02815	COG4717	serine-type aminopeptidase activity
KFE94_02830	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KFE94_02830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFE94_02885	COG0584	glycerophosphoryl diester phosphodiesterase
KFE94_02890	COG4753	response regulator
KFE94_02890	COG2207	Transcriptional regulator
KFE94_02975	COG0336	Belongs to the RNA methyltransferase TrmD family
KFE94_02980	COG0335	large ribosomal subunit rRNA binding
KFE94_02995	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFE94_02995	COG1388	LysM domain
KFE94_03000	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFE94_03000	COG0519	Catalyzes the synthesis of GMP from XMP
KFE94_03010	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KFE94_03020	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFE94_03025	COG0552	protein localization to endoplasmic reticulum
KFE94_03035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KFE94_03040	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KFE94_03045	COG1546	Belongs to the CinA family
KFE94_03045	COG1058	Belongs to the CinA family
KFE94_03050	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFE94_03055	COG1045	serine acetyltransferase
KFE94_03060	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KFE94_03080	COG1063	alcohol dehydrogenase
KFE94_03085	COG0367	asparagine synthase
KFE94_03100	COG1442	glycosyl transferase family 8
KFE94_03100	COG1216	Glycosyl transferase, family 2
KFE94_03110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFE94_03150	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
KFE94_03160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFE94_03170	COG0489	protein tyrosine kinase activity
KFE94_03170	COG3206	protein involved in exopolysaccharide biosynthesis
KFE94_03180	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KFE94_03185	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFE94_03210	COG1215	transferase activity, transferring glycosyl groups
KFE94_03210	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KFE94_03245	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFE94_03255	COG0230	Belongs to the bacterial ribosomal protein bL34 family
KFE94_03260	COG1132	(ABC) transporter
KFE94_03310	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFE94_03315	COG2089	acid synthase
KFE94_03330	COG1083	cytidylyl-transferase
KFE94_03335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFE94_03340	COG1086	Polysaccharide biosynthesis protein
KFE94_03350	COG2089	acid synthase
KFE94_03355	COG1083	cytidylyl-transferase
KFE94_03360	COG0357	Ribosomal RNA small subunit methyltransferase G
KFE94_03365	COG1595	DNA-templated transcription, initiation
KFE94_03375	COG0343	queuine tRNA-ribosyltransferase activity
KFE94_03385	COG0825	malonyl-CoA metabolic process
KFE94_03390	COG0305	Participates in initiation and elongation during chromosome replication
KFE94_03430	COG1028	Short-chain dehydrogenase reductase Sdr
KFE94_03475	COG1705	Flagellar rod assembly protein muramidase FlgJ
KFE94_03505	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KFE94_03520	COG1442	glycosyl transferase family 8
KFE94_03520	COG1216	Glycosyl transferase, family 2
KFE94_03525	COG0579	oxidoreductase
KFE94_03530	COG2270	Major facilitator Superfamily
KFE94_03545	COG1049	propionate catabolic process, 2-methylcitrate cycle
KFE94_03560	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KFE94_03565	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KFE94_03570	COG0577	efflux transmembrane transporter activity
KFE94_03575	COG0359	binds to the 23S rRNA
KFE94_03580	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KFE94_03585	COG0360	Binds together with S18 to 16S ribosomal RNA
KFE94_03595	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KFE94_03635	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KFE94_03650	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFE94_03670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFE94_03680	COG4589	Belongs to the CDS family
KFE94_03685	COG0688	phosphatidylethanolamine metabolic process
KFE94_03700	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KFE94_03705	COG1418	mRNA catabolic process
KFE94_03720	COG0739	heme binding
KFE94_03735	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFE94_03745	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFE94_03765	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KFE94_03770	COG2086	electron transfer activity
KFE94_03775	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFE94_03775	COG0022	dehydrogenase e1 component
KFE94_03780	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KFE94_03790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFE94_03815	COG0386	Belongs to the glutathione peroxidase family
KFE94_03820	COG0730	response to heat
KFE94_03825	COG1473	amidohydrolase
KFE94_03835	COG1999	signal sequence binding
KFE94_03850	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFE94_03855	COG1454	alcohol dehydrogenase
KFE94_03875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFE94_03880	COG0123	including yeast histone deacetylase and acetoin utilization protein
KFE94_03885	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFE94_03900	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KFE94_03905	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KFE94_03910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KFE94_03915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFE94_03970	COG3876	Protein conserved in bacteria
KFE94_03975	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFE94_03995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFE94_04000	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KFE94_04010	COG0463	Glycosyl transferase, family 2
KFE94_04015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFE94_04030	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KFE94_04040	COG0339	signal peptide processing
KFE94_04045	COG2195	Cleaves the N-terminal amino acid of tripeptides
KFE94_04055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFE94_04090	COG0564	pseudouridine synthase activity
KFE94_04105	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFE94_04110	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFE94_04115	COG0673	inositol 2-dehydrogenase activity
KFE94_04125	COG2912	Transglutaminase-like superfamily
KFE94_04130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KFE94_04135	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFE94_04160	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KFE94_04165	COG2089	acid synthase
KFE94_04180	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFE94_04200	COG1028	Short-chain dehydrogenase reductase Sdr
KFE94_04230	COG2003	Belongs to the UPF0758 family
KFE94_04235	COG0268	Binds directly to 16S ribosomal RNA
KFE94_04250	COG0442	prolyl-tRNA aminoacylation
KFE94_04265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KFE94_04270	COG1663	tetraacyldisaccharide 4'-kinase activity
KFE94_04280	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFE94_04285	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFE94_04305	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KFE94_04315	COG3118	belongs to the thioredoxin family
KFE94_04360	COG0148	phosphopyruvate hydratase activity
KFE94_04365	COG0505	Belongs to the CarA family
KFE94_04370	COG0203	ribosomal protein L17
KFE94_04375	COG0202	RNA polymerase activity
KFE94_04380	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KFE94_04385	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KFE94_04390	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KFE94_04395	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KFE94_04400	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KFE94_04410	COG0200	Binds to the 23S rRNA
KFE94_04415	COG1841	ribosomal large subunit assembly
KFE94_04420	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KFE94_04425	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KFE94_04430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KFE94_04435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KFE94_04440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFE94_04445	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFE94_04450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFE94_04455	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KFE94_04460	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFE94_04465	COG0255	Belongs to the universal ribosomal protein uL29 family
KFE94_04470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KFE94_04475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KFE94_04480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KFE94_04485	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KFE94_04490	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFE94_04495	COG0089	rRNA binding
KFE94_04500	COG0088	Forms part of the polypeptide exit tunnel
KFE94_04505	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KFE94_04510	COG0051	transcription antitermination factor activity, RNA binding
KFE94_04515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFE94_04520	COG0049	tRNA binding
KFE94_04525	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KFE94_04540	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFE94_04550	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFE94_04555	COG0484	heat shock protein binding
KFE94_04560	COG4152	abc transporter atp-binding protein
KFE94_04570	COG0248	Ppx GppA phosphatase
KFE94_04605	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KFE94_04610	COG0739	heme binding
KFE94_04620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFE94_04625	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KFE94_04640	COG0183	Belongs to the thiolase family
KFE94_04675	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFE94_04680	COG1024	Enoyl-CoA hydratase
KFE94_04690	COG4221	oxidoreductase activity
KFE94_04695	COG1505	serine-type exopeptidase activity
KFE94_04700	COG1012	belongs to the aldehyde dehydrogenase family
KFE94_04700	COG2030	dehydratase
KFE94_04710	COG1196	nuclear chromosome segregation
KFE94_04720	COG0022	dehydrogenase e1 component
KFE94_04740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KFE94_04765	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KFE94_04770	COG1160	GTP binding
KFE94_04800	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFE94_04805	COG3844	kynureninase activity
KFE94_04815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFE94_04825	COG1428	Deoxynucleoside kinase
KFE94_04845	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFE94_04865	COG2264	protein methyltransferase activity
KFE94_04870	COG3781	membrane
KFE94_04885	COG1022	Amp-dependent synthetase and ligase
KFE94_04890	COG2070	2-Nitropropane dioxygenase
KFE94_04900	COG1574	metal-dependent hydrolase with the TIM-barrel fold
KFE94_04915	COG1183	phosphatidylcholine synthase activity
KFE94_04935	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFE94_04955	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFE94_04975	COG0196	riboflavin kinase activity
KFE94_04985	COG4206	TonB-dependent receptor
KFE94_05025	COG1607	acyl-coa hydrolase
KFE94_05050	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KFE94_05065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFE94_05070	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KFE94_05080	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFE94_05085	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFE94_05090	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFE94_05105	COG0275	rRNA processing
KFE94_05110	COG2001	Belongs to the MraZ family
KFE94_05120	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KFE94_05125	COG0084	hydrolase, TatD family'
KFE94_05135	COG1846	Transcriptional regulator
KFE94_05140	COG0778	Nitroreductase
KFE94_05160	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFE94_05165	COG0720	synthase
KFE94_05190	COG4771	TonB-dependent receptor
KFE94_05215	COG1610	YqeY-like protein
KFE94_05220	COG2197	response regulator
KFE94_05260	COG1136	(ABC) transporter
KFE94_05260	COG0577	efflux transmembrane transporter activity
KFE94_05265	COG0577	efflux transmembrane transporter activity
KFE94_05265	COG1136	(ABC) transporter
KFE94_05310	COG0811	peptide transport
KFE94_05325	COG0252	asparaginase activity
KFE94_05330	COG0233	cytoplasmic translational termination
KFE94_05335	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KFE94_05370	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFE94_05375	COG0577	efflux transmembrane transporter activity
KFE94_05375	COG1136	(ABC) transporter
KFE94_05395	COG0702	epimerase
KFE94_05465	COG1404	Belongs to the peptidase S8 family
KFE94_05465	COG4412	M6 family metalloprotease domain protein
KFE94_05470	COG0564	pseudouridine synthase activity
KFE94_05475	COG2318	DinB family
KFE94_05480	COG0596	Alpha beta hydrolase
KFE94_05485	COG1309	transcriptional regulator
KFE94_05500	COG0488	(ABC) transporter
KFE94_05515	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFE94_05520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFE94_05525	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFE94_05540	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFE94_05545	COG0113	porphobilinogen synthase activity
KFE94_05550	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFE94_05555	COG1981	membrane
KFE94_05570	COG1917	Cupin 2, conserved barrel domain protein
KFE94_05570	COG2169	Transcriptional regulator
KFE94_05575	COG0386	Belongs to the glutathione peroxidase family
KFE94_05580	COG1846	Transcriptional regulator
KFE94_05595	COG1741	Belongs to the pirin family
KFE94_05600	COG0778	Nitroreductase
KFE94_05620	COG0316	Belongs to the HesB IscA family
KFE94_05625	COG0719	Fe-S assembly protein
KFE94_05630	COG0396	ATPase activity
KFE94_05635	COG0719	Fe-S assembly protein
KFE94_05640	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFE94_05645	COG2166	iron-sulfur cluster assembly
KFE94_05650	COG2151	metal-sulfur cluster biosynthetic enzyme
KFE94_05685	COG1595	DNA-templated transcription, initiation
KFE94_05700	COG3291	Pkd domain containing protein
KFE94_05710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFE94_05715	COG0697	spore germination
KFE94_05725	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFE94_05745	COG1090	epimerase
KFE94_05750	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFE94_05775	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFE94_05785	COG1566	PFAM secretion protein HlyD family protein
KFE94_05800	COG0528	UMP kinase activity
KFE94_05805	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFE94_05810	COG0052	Belongs to the universal ribosomal protein uS2 family
KFE94_05815	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KFE94_05820	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KFE94_05830	COG3185	4-Hydroxyphenylpyruvate dioxygenase
KFE94_05835	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
KFE94_05850	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFE94_05900	COG1073	alpha beta
KFE94_05905	COG2267	carboxylic ester hydrolase activity
KFE94_05920	COG4452	Inner membrane protein CreD
KFE94_05925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KFE94_05930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KFE94_05935	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KFE94_05950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KFE94_05965	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFE94_05970	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFE94_05985	COG1331	Highly conserved protein containing a thioredoxin domain
KFE94_06005	COG0784	Response regulator, receiver
KFE94_06005	COG2205	protein histidine kinase activity
KFE94_06010	COG3292	Two component regulator propeller
KFE94_06010	COG2205	protein histidine kinase activity
KFE94_06010	COG0745	RESPONSE REGULATOR receiver
KFE94_06025	COG0463	Glycosyl transferase, family 2
KFE94_06035	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KFE94_06045	COG1705	Flagellar rod assembly protein muramidase FlgJ
KFE94_06045	COG1388	LysM domain
KFE94_06065	COG0322	excinuclease ABC activity
KFE94_06070	COG1360	Flagellar Motor Protein
KFE94_06075	COG0495	leucyl-tRNA aminoacylation
KFE94_06100	COG1960	acyl-CoA dehydrogenase activity
KFE94_06115	COG0594	ribonuclease P activity
KFE94_06130	COG0463	Glycosyl transferase, family 2
KFE94_06135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KFE94_06155	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KFE94_06165	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KFE94_06170	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KFE94_06170	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KFE94_06180	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KFE94_06185	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KFE94_06190	COG0297	glycogen (starch) synthase activity
KFE94_06200	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFE94_06215	COG1629	transport
KFE94_06215	COG4206	TonB-dependent receptor
KFE94_06310	COG0640	Transcriptional regulator
KFE94_06320	COG4974	Belongs to the 'phage' integrase family
KFE94_06330	COG4191	Histidine kinase
KFE94_06355	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFE94_06360	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KFE94_06365	COG0193	aminoacyl-tRNA hydrolase activity
KFE94_06375	COG1040	competence protein
KFE94_06380	COG1956	GAF domain-containing protein
KFE94_06405	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFE94_06415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KFE94_06440	COG1132	(ABC) transporter
KFE94_06455	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KFE94_06485	COG3118	belongs to the thioredoxin family
KFE94_06495	COG1054	Belongs to the UPF0176 family
KFE94_06530	COG0427	acetyl-CoA hydrolase
KFE94_06545	COG4565	transcriptional regulatory protein
KFE94_06640	COG0531	amino acid
KFE94_06645	COG0626	cystathionine gamma-synthase activity
KFE94_06650	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFE94_06685	COG1845	cytochrome c oxidase, subunit III
KFE94_06695	COG4771	TonB-dependent receptor
KFE94_06705	COG2010	Cytochrome c
KFE94_06725	COG3256	nitric oxide reductase
KFE94_06730	COG2010	Cytochrome c
KFE94_06735	COG1959	2 iron, 2 sulfur cluster binding
KFE94_06740	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
KFE94_06760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KFE94_06770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFE94_06775	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFE94_06785	COG4682	membrane
KFE94_06800	COG3708	Transcriptional regulator
KFE94_06800	COG2207	Transcriptional regulator
KFE94_06825	COG4946	Tricorn protease homolog
KFE94_06825	COG0793	Belongs to the peptidase S41A family
KFE94_06845	COG1858	cytochrome C peroxidase
KFE94_06900	COG0714	Associated with various cellular activities
KFE94_06910	COG3119	arylsulfatase activity
KFE94_06915	COG2207	Transcriptional regulator
KFE94_06920	COG3119	arylsulfatase activity
KFE94_06930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KFE94_06935	COG1511	domain protein
KFE94_06935	COG3264	Mechanosensitive ion channel
KFE94_06955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFE94_07025	COG1528	Iron-storage protein
KFE94_07030	COG0557	exoribonuclease II activity
KFE94_07040	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFE94_07065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFE94_07075	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KFE94_07080	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KFE94_07085	COG3781	membrane
KFE94_07090	COG4628	conserved protein (DUF2132)
KFE94_07100	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KFE94_07110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KFE94_07120	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFE94_07125	COG2255	four-way junction helicase activity
KFE94_07130	COG2264	protein methyltransferase activity
KFE94_07275	COG4968	Prepilin-type N-terminal cleavage methylation domain
KFE94_07280	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFE94_07330	COG1459	type II secretion system
KFE94_07345	COG1136	(ABC) transporter
KFE94_07350	COG0577	efflux transmembrane transporter activity
KFE94_07350	COG1136	(ABC) transporter
KFE94_07355	COG0577	efflux transmembrane transporter activity
KFE94_07355	COG1136	(ABC) transporter
KFE94_07360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFE94_07370	COG0569	domain protein
KFE94_07375	COG1595	DNA-templated transcription, initiation
KFE94_07395	COG1404	Belongs to the peptidase S8 family
KFE94_07395	COG4412	M6 family metalloprotease domain protein
KFE94_07400	COG1028	Short-chain dehydrogenase reductase Sdr
KFE94_07415	COG2204	response regulator
KFE94_07450	COG0110	maltose O-acetyltransferase activity
KFE94_07470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFE94_07475	COG1733	regulation of RNA biosynthetic process
KFE94_07505	COG1770	oligopeptidase
KFE94_07510	COG1629	transport
KFE94_07510	COG4206	TonB-dependent receptor
KFE94_07525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFE94_07525	COG0047	phosphoribosylformylglycinamidine synthase activity
KFE94_07590	COG1309	transcriptional regulator
KFE94_07610	COG1162	GTPase activity
KFE94_07685	COG1309	transcriptional regulator
KFE94_07705	COG2957	Belongs to the agmatine deiminase family
KFE94_07725	COG2267	carboxylic ester hydrolase activity
KFE94_07735	COG1011	Hydrolase
KFE94_07745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFE94_07785	COG0180	Tryptophanyl-tRNA synthetase
KFE94_07790	COG1024	Enoyl-CoA hydratase
KFE94_07795	COG5000	phosphorelay sensor kinase activity
KFE94_07800	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFE94_07810	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFE94_07810	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFE94_07825	COG0215	cysteine-tRNA ligase activity
KFE94_07830	COG0583	DNA-binding transcription factor activity
KFE94_07835	COG0823	Involved in the tonB-independent uptake of proteins
KFE94_07835	COG1506	peptidase
KFE94_07845	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFE94_07870	COG1381	Involved in DNA repair and RecF pathway recombination
KFE94_07880	COG0445	tRNA wobble uridine modification
KFE94_07885	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KFE94_07900	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFE94_07900	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
KFE94_07905	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFE94_07925	COG0698	ribose 5-phosphate isomerase
KFE94_08000	COG1228	amidohydrolase
KFE94_08010	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KFE94_08010	COG3264	Mechanosensitive ion channel
KFE94_08015	COG0006	proline dipeptidase activity
KFE94_08020	COG1283	sodium-dependent phosphate transmembrane transporter activity
KFE94_08025	COG4206	TonB-dependent receptor
KFE94_08025	COG1629	transport
KFE94_08040	COG0205	6-phosphofructokinase activity
KFE94_08095	COG0488	(ABC) transporter
KFE94_08110	COG1053	succinate dehydrogenase
KFE94_08130	COG2197	response regulator
KFE94_08135	COG4585	Histidine kinase
KFE94_08145	COG0126	phosphoglycerate kinase activity
KFE94_08150	COG0470	DNA polymerase III
KFE94_08155	COG0756	dUTP diphosphatase activity
KFE94_08160	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KFE94_08180	COG0463	Glycosyl transferase, family 2
KFE94_08195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KFE94_08200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KFE94_08215	COG1774	PSP1 C-terminal conserved region
KFE94_08240	COG0590	tRNA wobble adenosine to inosine editing
KFE94_08250	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KFE94_08255	COG0280	phosphate acetyltransferase
KFE94_08255	COG0857	belongs to the CobB CobQ family
KFE94_08260	COG0469	pyruvate kinase activity
KFE94_08270	COG0571	ribonuclease III activity
KFE94_08275	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFE94_08280	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFE94_08335	COG0437	4 iron, 4 sulfur cluster binding
KFE94_08365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFE94_08385	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KFE94_08390	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFE94_08395	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFE94_08400	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFE94_08405	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFE94_08410	COG0356	it plays a direct role in the translocation of protons across the membrane
KFE94_08435	COG4942	peptidase
KFE94_08440	COG0328	RNA-DNA hybrid ribonuclease activity
KFE94_08450	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFE94_08460	COG0481	GTPase activity
KFE94_08480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFE94_08505	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KFE94_08510	COG0281	malic enzyme
KFE94_08510	COG0280	phosphate acetyltransferase
KFE94_08515	COG0632	four-way junction helicase activity
KFE94_08525	COG0509	glycine decarboxylation via glycine cleavage system
KFE94_08540	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KFE94_08560	COG0109	protoheme IX farnesyltransferase activity
KFE94_08570	COG1845	cytochrome c oxidase, subunit III
KFE94_08585	COG2322	membrane
KFE94_08600	COG0739	heme binding
KFE94_08600	COG1196	nuclear chromosome segregation
KFE94_08600	COG0741	lytic transglycosylase activity
KFE94_08620	COG1028	Short-chain dehydrogenase reductase Sdr
KFE94_08625	COG0662	Cupin 2, conserved barrel domain protein
KFE94_08635	COG1752	Esterase of the alpha-beta hydrolase superfamily
KFE94_08645	COG0142	geranyltranstransferase activity
KFE94_08650	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFE94_08655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFE94_08660	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KFE94_08665	COG1968	undecaprenyl-diphosphatase activity
KFE94_08675	COG2177	Part of the ABC transporter FtsEX involved in
KFE94_08685	COG0017	Asparaginyl-tRNA synthetase
KFE94_08710	COG0436	Aminotransferase
KFE94_08745	COG1032	radical SAM domain protein
KFE94_08790	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
KFE94_08795	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KFE94_08810	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KFE94_08850	COG0321	lipoyl(octanoyl) transferase activity
KFE94_08855	COG2222	sugar isomerase
KFE94_08860	COG0779	Required for maturation of 30S ribosomal subunits
KFE94_08865	COG0195	Participates in both transcription termination and antitermination
KFE94_08870	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KFE94_08985	COG0423	glycine-tRNA ligase activity
KFE94_09010	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFE94_09015	COG1595	DNA-templated transcription, initiation
KFE94_09040	COG0758	DNA mediated transformation
KFE94_09045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KFE94_09050	COG0156	8-amino-7-oxononanoate synthase activity
KFE94_09070	COG0489	protein tyrosine kinase activity
KFE94_09075	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
KFE94_09085	COG0671	phosphoesterase, PA-phosphatase related
KFE94_09110	COG1914	H( )-stimulated, divalent metal cation uptake system
KFE94_09115	COG3698	Phosphodiester glycosidase
KFE94_09120	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFE94_09125	COG1136	(ABC) transporter
KFE94_09135	COG1858	cytochrome C peroxidase
KFE94_09145	COG0037	tRNA processing
KFE94_09160	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KFE94_09175	COG0606	chelatase, subunit chli
KFE94_09185	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KFE94_09200	COG0151	Belongs to the GarS family
KFE94_09205	COG0439	Biotin carboxylase
KFE94_09210	COG0511	ligase activity, forming carbon-carbon bonds
KFE94_09215	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFE94_09220	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KFE94_09230	COG1619	proteins homologs of microcin C7 resistance protein MccF
KFE94_09235	COG0792	nuclease activity
KFE94_09240	COG1187	pseudouridine synthase activity
KFE94_09250	COG3852	Histidine kinase
KFE94_09255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFE94_09265	COG1522	sequence-specific DNA binding
KFE94_09285	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFE94_09295	COG1561	YicC-like family, N-terminal region
KFE94_09300	COG0194	GDP metabolic process
KFE94_09305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFE94_09310	COG0859	PFAM glycosyl transferase family 9
KFE94_09315	COG0535	radical SAM domain protein
KFE94_09325	COG0823	Involved in the tonB-independent uptake of proteins
KFE94_09325	COG1506	peptidase
KFE94_09330	COG1573	uracil-dna glycosylase
KFE94_09335	COG0577	efflux transmembrane transporter activity
KFE94_09335	COG1136	(ABC) transporter
KFE94_09340	COG0138	bifunctional purine biosynthesis protein purh
KFE94_09360	COG0768	penicillin binding
KFE94_09365	COG0772	Belongs to the SEDS family
KFE94_09385	COG1012	belongs to the aldehyde dehydrogenase family
KFE94_09395	COG5002	protein histidine kinase activity
KFE94_09420	COG0745	RESPONSE REGULATOR receiver
KFE94_09425	COG5002	protein histidine kinase activity
KFE94_09430	COG0009	L-threonylcarbamoyladenylate synthase
KFE94_09440	COG1490	D-aminoacyl-tRNA deacylase activity
KFE94_09445	COG0527	aspartate kinase activity
KFE94_09475	COG1566	PFAM secretion protein HlyD family protein
KFE94_09495	COG1131	(ABC) transporter
KFE94_09525	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFE94_09545	COG1253	flavin adenine dinucleotide binding
KFE94_09550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFE94_09555	COG3340	Belongs to the peptidase S51 family
KFE94_09560	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KFE94_09570	COG0826	peptidase U32
KFE94_09605	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFE94_09605	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFE94_09620	COG1127	ABC transporter
KFE94_09625	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFE94_09645	COG1393	Belongs to the ArsC family
KFE94_09660	COG2137	regulation of response to DNA damage stimulus
KFE94_09665	COG1530	ribonuclease E activity
KFE94_09670	COG0776	regulation of translation
KFE94_09675	COG1194	a g-specific adenine glycosylase
KFE94_09680	COG0629	single-stranded DNA binding
KFE94_09685	COG4535	Mg2 and Co2 transporter CorC
KFE94_09695	COG1612	heme a metabolic process
KFE94_09705	COG0805	protein transport
KFE94_09715	COG1137	ATPase activity
KFE94_09720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KFE94_09745	COG0714	Associated with various cellular activities
KFE94_09755	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFE94_09760	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFE94_09765	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFE94_09765	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KFE94_09770	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFE94_09780	COG1078	dGTPase activity
KFE94_09805	COG3548	integral membrane protein
KFE94_09815	COG0686	Belongs to the AlaDH PNT family
KFE94_09830	COG1917	Cupin 2, conserved barrel domain protein
KFE94_09830	COG4977	sequence-specific DNA binding
KFE94_09845	COG0527	aspartate kinase activity
KFE94_09845	COG0460	homoserine dehydrogenase
KFE94_09850	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFE94_09865	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFE94_09870	COG0646	methionine synthase
KFE94_09870	COG1410	methionine synthase
KFE94_09875	COG0646	methionine synthase
KFE94_09875	COG1410	methionine synthase
KFE94_09880	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFE94_09900	COG1252	NADH dehydrogenase
KFE94_09905	COG0339	signal peptide processing
KFE94_09915	COG0730	response to heat
KFE94_09930	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
KFE94_09940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KFE94_09975	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFE94_09985	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KFE94_09995	COG1215	transferase activity, transferring glycosyl groups
KFE94_10025	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KFE94_10050	COG4263	nitrous-oxide reductase activity
KFE94_10070	COG4152	abc transporter atp-binding protein
KFE94_10090	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
KFE94_10100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KFE94_10105	COG3396	Phenylacetate-CoA oxygenase
KFE94_10110	COG3460	Phenylacetate-CoA oxygenase
KFE94_10115	COG3396	Phenylacetate-CoA oxygenase
KFE94_10120	COG2151	metal-sulfur cluster biosynthetic enzyme
KFE94_10130	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KFE94_10135	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KFE94_10140	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFE94_10145	COG0563	adenylate kinase activity
KFE94_10150	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFE94_10155	COG2239	Acts as a magnesium transporter
KFE94_10160	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFE94_10175	COG0463	Glycosyl transferase, family 2
KFE94_10200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFE94_10205	COG0154	amidase activity
KFE94_10215	COG0596	Alpha beta hydrolase
KFE94_10220	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KFE94_10225	COG0516	GMP reductase activity
KFE94_10225	COG0517	IMP dehydrogenase activity
KFE94_10235	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KFE94_10250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KFE94_10270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KFE94_10275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFE94_10290	COG0358	DNA primase activity
KFE94_10310	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KFE94_10310	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
KFE94_10320	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KFE94_10330	COG0584	glycerophosphoryl diester phosphodiesterase
KFE94_10335	COG2096	Adenosyltransferase
KFE94_10345	COG0653	protein targeting
KFE94_10355	COG1115	amino acid carrier protein
KFE94_10370	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFE94_10390	COG4585	Histidine kinase
KFE94_10405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KFE94_10410	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
KFE94_10425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFE94_10430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFE94_10440	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KFE94_10450	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KFE94_10480	COG0459	protein refolding
KFE94_10485	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KFE94_10510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFE94_10530	COG0515	serine threonine protein kinase
KFE94_10530	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFE94_10555	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KFE94_10590	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFE94_10595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFE94_10610	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFE94_10615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFE94_10620	COG0616	signal peptide processing
KFE94_10635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KFE94_10640	COG0295	cytidine deaminase activity
KFE94_10665	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFE94_10670	COG1960	acyl-CoA dehydrogenase activity
KFE94_10685	COG0811	peptide transport
KFE94_10690	COG0848	biopolymer transport protein
KFE94_10700	COG0285	dihydrofolate synthase activity
KFE94_10710	COG0039	L-malate dehydrogenase activity
KFE94_10735	COG0706	membrane insertase activity
KFE94_10740	COG0504	CTP synthase activity
KFE94_10770	COG3011	Protein conserved in bacteria
KFE94_10775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFE94_10780	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFE94_10795	COG2885	chlorophyll binding
KFE94_10800	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KFE94_10805	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFE94_10810	COG0284	orotidine-5'-phosphate decarboxylase activity
KFE94_10825	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KFE94_10830	COG1091	dTDP-4-dehydrorhamnose reductase activity
KFE94_10835	COG1115	amino acid carrier protein
KFE94_10845	COG1960	acyl-CoA dehydrogenase activity
KFE94_10850	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KFE94_10855	COG4974	Belongs to the 'phage' integrase family
KFE94_10885	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFE94_10905	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFE94_10910	COG0081	regulation of translation
KFE94_10915	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KFE94_10920	COG0222	ribosome binding
KFE94_10925	COG0085	RNA polymerase activity
KFE94_10930	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFE94_10940	COG1752	Esterase of the alpha-beta hydrolase superfamily
KFE94_10945	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KFE94_10970	COG1595	DNA-templated transcription, initiation
KFE94_10995	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFE94_11000	COG0658	competence protein
KFE94_11000	COG2333	competence protein COMEC
KFE94_11005	COG2385	sporulation resulting in formation of a cellular spore
KFE94_11005	COG2247	cell wall binding repeat
KFE94_11010	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFE94_11020	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KFE94_11050	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KFE94_11060	COG1028	Short-chain dehydrogenase reductase Sdr
KFE94_11135	COG4770	biotin carboxylase activity
KFE94_11140	COG0308	aminopeptidase N
KFE94_11145	COG3152	Membrane
KFE94_11165	COG1215	transferase activity, transferring glycosyl groups
KFE94_11200	COG2197	response regulator
KFE94_11205	COG4585	Histidine kinase
KFE94_11210	COG0564	pseudouridine synthase activity
KFE94_11225	COG0513	Belongs to the DEAD box helicase family
KFE94_11300	COG3541	Predicted nucleotidyltransferase
KFE94_11370	COG4585	Histidine kinase
KFE94_11410	COG1012	belongs to the aldehyde dehydrogenase family
KFE94_11495	COG0556	nucleotide-excision repair
KFE94_11505	COG0217	transcriptional regulatory protein
KFE94_11510	COG1696	Membrane protein involved in D-alanine export
KFE94_11525	COG1705	Flagellar rod assembly protein muramidase FlgJ
KFE94_11525	COG1388	LysM domain
KFE94_11540	COG0471	metal ion transport
KFE94_11545	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFE94_11560	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFE94_11570	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KFE94_11585	COG0038	chloride channel
KFE94_11595	COG1522	sequence-specific DNA binding
KFE94_11600	COG0436	Aminotransferase
KFE94_11605	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFE94_11610	COG3104	oligopeptide transport
KFE94_11690	COG0702	epimerase
KFE94_11720	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
KFE94_11740	COG4106	trans-aconitate 2-methyltransferase activity
KFE94_11745	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KFE94_11745	COG2207	Transcriptional regulator
KFE94_11800	COG1858	cytochrome C peroxidase
KFE94_11815	COG2267	carboxylic ester hydrolase activity
KFE94_11835	COG2267	carboxylic ester hydrolase activity
KFE94_11850	COG0688	phosphatidylethanolamine metabolic process
KFE94_11870	COG0463	Glycosyl transferase, family 2
KFE94_11890	COG2207	Transcriptional regulator
KFE94_11910	COG2234	aminopeptidase activity
KFE94_11980	COG0519	Catalyzes the synthesis of GMP from XMP
KFE94_11985	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFE94_11990	COG1185	polyribonucleotide nucleotidyltransferase activity
KFE94_11995	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KFE94_12000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFE94_12005	COG1830	Aldolase
KFE94_12015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFE94_12025	COG2226	methyltransferase
KFE94_12040	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KFE94_12045	COG0717	Belongs to the dCTP deaminase family
KFE94_12065	COG1858	cytochrome C peroxidase
KFE94_12070	COG1858	cytochrome C peroxidase
KFE94_12075	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KFE94_12095	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
KFE94_12120	COG1401	restriction endodeoxyribonuclease activity
KFE94_12130	COG2957	Belongs to the agmatine deiminase family
KFE94_12145	COG2827	Endonuclease containing a URI domain
KFE94_12155	COG1294	oxidase, subunit
KFE94_12160	COG1271	oxidase subunit
KFE94_12210	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFE94_12250	COG0037	tRNA processing
KFE94_12260	COG0514	ATP-dependent DNA helicase (RecQ)
KFE94_12295	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KFE94_12310	COG1741	Belongs to the pirin family
KFE94_12315	COG2353	YceI-like domain
KFE94_12360	COG3384	dioxygenase
KFE94_12370	COG0596	Alpha beta hydrolase
KFE94_12390	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KFE94_12415	COG4977	sequence-specific DNA binding
KFE94_12415	COG1917	Cupin 2, conserved barrel domain protein
KFE94_12425	COG1881	PFAM PEBP family protein
KFE94_12465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KFE94_12480	COG2890	protein-(glutamine-N5) methyltransferase activity
KFE94_12515	COG1028	Short-chain dehydrogenase reductase Sdr
KFE94_12535	COG0024	Methionine aminopeptidase
KFE94_12575	COG1733	regulation of RNA biosynthetic process
KFE94_12595	COG2226	methyltransferase
KFE94_12605	COG0142	geranyltranstransferase activity
KFE94_12655	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KFE94_12680	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFE94_12710	COG0798	PFAM Bile acid sodium symporter
KFE94_12735	COG2501	S4 domain
KFE94_12740	COG3530	Putative quorum-sensing-regulated virulence factor
KFE94_12750	COG0681	Belongs to the peptidase S26 family
KFE94_12750	COG0681	Belongs to the peptidase S26 family
KFE94_12755	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KFE94_12765	COG1475	DNA binding
KFE94_12770	COG1192	Involved in chromosome partitioning
KFE94_12780	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFE94_12785	COG0432	Pfam Uncharacterised protein family UPF0047
KFE94_12805	COG2197	response regulator
KFE94_12810	COG4585	Histidine kinase
KFE94_12815	COG0564	pseudouridine synthase activity
KFE94_12820	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFE94_12830	COG0443	Heat shock 70 kDa protein
KFE94_12855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFE94_12865	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KFE94_12870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFE94_12890	COG0450	alkyl hydroperoxide reductase
KFE94_12900	COG2226	methyltransferase
KFE94_12915	COG1301	dicarboxylic acid transport
KFE94_12925	COG0022	dehydrogenase e1 component
KFE94_12970	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFE94_12985	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
KFE94_12995	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFE94_13005	COG2972	Histidine kinase
KFE94_13025	COG1063	alcohol dehydrogenase
KFE94_13110	COG1960	acyl-CoA dehydrogenase activity
KFE94_13115	COG0183	Belongs to the thiolase family
KFE94_13120	COG1024	Enoyl-CoA hydratase
KFE94_13120	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFE94_13130	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFE94_13135	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFE94_13140	COG3591	Belongs to the peptidase S1B family
KFE94_13150	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KFE94_13155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFE94_13165	COG0156	8-amino-7-oxononanoate synthase activity
KFE94_13190	COG1193	negative regulation of DNA recombination
KFE94_13200	COG0564	pseudouridine synthase activity
KFE94_13210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFE94_13215	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFE94_13220	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KFE94_13265	COG0545	Peptidyl-prolyl cis-trans isomerase
KFE94_13325	COG1702	phosphate starvation-inducible protein PhoH
KFE94_13330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KFE94_13360	COG0019	diaminopimelate decarboxylase activity
KFE94_13385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFE94_13390	COG0674	pyruvate-flavodoxin oxidoreductase activity
KFE94_13390	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KFE94_13395	COG1013	pyruvate-flavodoxin oxidoreductase activity
KFE94_13405	COG2855	membrane
KFE94_13410	COG1950	PFAM Membrane protein of
KFE94_13425	COG0439	Biotin carboxylase
KFE94_13445	COG0436	Aminotransferase
KFE94_13460	COG2197	response regulator
KFE94_13470	COG1012	belongs to the aldehyde dehydrogenase family
KFE94_13475	COG0513	Belongs to the DEAD box helicase family
KFE94_13505	COG0124	histidyl-tRNA synthetase
KFE94_13510	COG2986	histidine ammonia-lyase
KFE94_13520	COG0589	response to stress
KFE94_13550	COG0602	queuosine metabolic process
KFE94_13560	COG0101	tRNA pseudouridine synthase activity
KFE94_13580	COG1472	Belongs to the glycosyl hydrolase 3 family
KFE94_13585	COG0438	transferase activity, transferring glycosyl groups
KFE94_13635	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KFE94_13640	COG2363	Small membrane protein
KFE94_13645	COG1028	Short-chain dehydrogenase reductase Sdr
KFE94_13660	COG1074	ATP-dependent DNA helicase activity
KFE94_13665	COG0784	Response regulator, receiver
KFE94_13665	COG5002	protein histidine kinase activity
KFE94_13665	COG2198	Histidine kinase
KFE94_13685	COG3956	TIGRFAM MazG family protein
KFE94_13700	COG2258	MOSC domain
KFE94_13705	COG1418	mRNA catabolic process
KFE94_13740	COG1132	(ABC) transporter
KFE94_13745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFE94_13755	COG1862	Preprotein translocase
KFE94_13765	COG0237	dephospho-CoA kinase activity
KFE94_13775	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KFE94_13775	COG0321	lipoyl(octanoyl) transferase activity
KFE94_13785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFE94_13795	COG2234	aminopeptidase activity
KFE94_13805	COG3781	membrane
KFE94_13810	COG0300	oxidoreductase activity
KFE94_13835	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KFE94_13840	COG1805	sodium ion transport
KFE94_13845	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KFE94_13850	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KFE94_13855	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
KFE94_13865	COG1477	protein flavinylation
KFE94_13870	COG1132	(ABC) transporter
KFE94_13875	COG0390	transport system, permease component
KFE94_13895	COG3842	ATPase activity
KFE94_13910	COG3645	SOS response
KFE94_13970	COG4221	oxidoreductase activity
KFE94_13980	COG4221	oxidoreductase activity
KFE94_13985	COG0702	epimerase
KFE94_14000	COG0525	valine-tRNA ligase activity
KFE94_14005	COG1696	Membrane protein involved in D-alanine export
KFE94_14015	COG4247	3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase)
KFE94_14080	COG1131	(ABC) transporter
KFE94_14145	COG3279	Response regulator of the LytR AlgR family
KFE94_14180	COG0012	GTP binding
KFE94_14205	COG1595	DNA-templated transcription, initiation
KFE94_14220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFE94_14245	COG1228	amidohydrolase
KFE94_14270	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFE94_14295	COG0626	cystathionine gamma-synthase activity
KFE94_14320	COG2197	response regulator
KFE94_14330	COG2197	response regulator
KFE94_14365	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
KFE94_14420	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KFE94_14475	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KFE94_14480	COG0545	Peptidyl-prolyl cis-trans isomerase
KFE94_14490	COG0784	Response regulator, receiver
KFE94_14490	COG2205	protein histidine kinase activity
KFE94_14500	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KFE94_14505	COG2045	Belongs to the ComB family
KFE94_14515	COG0542	response to heat
KFE94_14520	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KFE94_14570	COG1047	Peptidyl-prolyl cis-trans
KFE94_14585	COG1858	cytochrome C peroxidase
KFE94_14635	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KFE94_14645	COG1809	phosphosulfolactate synthase activity
KFE94_14655	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFE94_14660	COG1104	cysteine desulfurase activity
KFE94_14670	COG0700	Nucleoside recognition
KFE94_14680	COG0009	L-threonylcarbamoyladenylate synthase
KFE94_14695	COG0254	rRNA binding
KFE94_14705	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KFE94_14715	COG1217	gtp-binding protein TYPA
KFE94_14745	COG0612	Peptidase, M16
KFE94_14755	COG4122	O-methyltransferase activity
KFE94_14760	COG0612	Peptidase, M16
KFE94_14765	COG0513	Belongs to the DEAD box helicase family
KFE94_14780	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFE94_14780	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFE94_14800	COG3590	peptidase
KFE94_14805	COG0628	permease
KFE94_14810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KFE94_14825	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KFE94_14830	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFE94_14840	COG0617	tRNA 3'-terminal CCA addition
KFE94_14850	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KFE94_14865	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KFE94_14920	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KFE94_14925	COG0242	peptide deformylase activity
KFE94_14940	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFE94_14955	COG0149	triose-phosphate isomerase activity
KFE94_14960	COG2264	protein methyltransferase activity
KFE94_14995	COG4864	UPF0365 protein
KFE94_15000	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFE94_15010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFE94_15015	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFE94_15015	COG1703	isobutyryl-CoA mutase activity
KFE94_15015	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFE94_15045	COG1575	Belongs to the MenA family. Type 1 subfamily
KFE94_15065	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KFE94_15085	COG0516	GMP reductase activity
KFE94_15085	COG0517	IMP dehydrogenase activity
KFE94_15090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFE94_15100	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFE94_15105	COG0714	Associated with various cellular activities
KFE94_15115	COG2885	chlorophyll binding
KFE94_15120	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFE94_15130	COG0653	protein targeting
KFE94_15145	COG0010	Belongs to the arginase family
KFE94_15150	COG0018	arginyl-trna synthetase
KFE94_15155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFE94_15160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFE94_15165	COG0655	NAD(P)H dehydrogenase (quinone) activity
KFE94_15195	COG2205	protein histidine kinase activity
KFE94_15200	COG0659	secondary active sulfate transmembrane transporter activity
KFE94_15210	COG1959	2 iron, 2 sulfur cluster binding
KFE94_15220	COG0175	sulfate reduction
KFE94_15225	COG0175	sulfate reduction
KFE94_15260	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KFE94_15265	COG1733	regulation of RNA biosynthetic process
KFE94_15285	COG4221	oxidoreductase activity
KFE94_15290	COG0583	DNA-binding transcription factor activity
KFE94_15350	COG0010	Belongs to the arginase family
KFE94_15375	COG0482	sulfurtransferase activity
KFE94_15400	COG0501	Belongs to the peptidase M48B family
KFE94_15435	COG1595	DNA-templated transcription, initiation
KFE94_15485	COG2378	regulation of single-species biofilm formation
KFE94_15490	COG4335	DNA alkylation repair
KFE94_15500	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFE94_15540	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KFE94_15555	COG1032	radical SAM domain protein
KFE94_15560	COG4974	Belongs to the 'phage' integrase family
KFE94_15575	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KFE94_15580	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFE94_15580	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFE94_15585	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KFE94_15595	COG4771	TonB-dependent receptor
KFE94_15600	COG0488	(ABC) transporter
KFE94_15610	COG0604	alcohol dehydrogenase
KFE94_15610	COG1028	Short-chain dehydrogenase reductase Sdr
KFE94_15610	COG3321	synthase
KFE94_15635	COG2095	MarC family integral membrane protein
KFE94_15675	COG3655	Transcriptional regulator
KFE94_15705	COG0534	Mate efflux family protein
KFE94_15715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFE94_15735	COG1301	dicarboxylic acid transport
KFE94_15745	COG0247	lactate metabolic process
KFE94_15745	COG0277	FAD linked oxidase domain protein
KFE94_15755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFE94_15765	COG1570	exodeoxyribonuclease VII activity
KFE94_15785	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KFE94_15790	COG0668	transmembrane transport
KFE94_15800	COG0318	PFAM AMP-dependent synthetase and ligase
KFE94_15805	COG1757	Na H antiporter
KFE94_15865	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFE94_15875	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFE94_15880	COG1506	peptidase
KFE94_15880	COG0823	Involved in the tonB-independent uptake of proteins
KFE94_15900	COG0745	RESPONSE REGULATOR receiver
KFE94_15950	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFE94_15990	COG0492	ferredoxin-NADP+ reductase activity
KFE94_16040	COG1819	glycosyl
KFE94_16060	COG0534	Mate efflux family protein
KFE94_16065	COG3483	tryptophan 2,3-dioxygenase activity
KFE94_16080	COG0415	Belongs to the DNA photolyase family
KFE94_16095	COG3118	belongs to the thioredoxin family
KFE94_16110	COG3033	Beta-eliminating lyase
KFE94_16120	COG1032	radical SAM domain protein
KFE94_16135	COG0641	radical SAM
KFE94_16150	COG1678	Uncharacterized ACR, COG1678
KFE94_16165	COG3383	formate dehydrogenase (NAD+) activity
KFE94_16170	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KFE94_16180	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFE94_16250	COG1607	acyl-coa hydrolase
KFE94_16295	COG4221	oxidoreductase activity
KFE94_16300	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KFE94_16310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KFE94_16330	COG1199	ATP-dependent helicase activity
KFE94_16330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFE94_16350	COG3609	addiction module antidote protein, CC2985 family
KFE94_16360	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFE94_16365	COG2022	thiamine diphosphate biosynthetic process
KFE94_16370	COG0352	thiamine-phosphate diphosphorylase activity
KFE94_16375	COG0351	phosphomethylpyrimidine kinase
KFE94_16375	COG0352	thiamine-phosphate diphosphorylase activity
KFE94_16375	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KFE94_16385	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KFE94_16420	COG1917	Cupin 2, conserved barrel domain protein
KFE94_16420	COG2207	Transcriptional regulator
KFE94_16490	COG0483	inositol monophosphate 1-phosphatase activity
KFE94_16495	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KFE94_16505	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFE94_16515	COG0513	Belongs to the DEAD box helicase family
KFE94_16525	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KFE94_16530	COG0303	'Molybdopterin
KFE94_16555	COG0564	pseudouridine synthase activity
KFE94_16570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFE94_16580	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFE94_16595	COG0251	oxidation-reduction process
KFE94_16660	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KFE94_16670	COG3104	oligopeptide transport
KFE94_16685	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KFE94_16690	COG0497	DNA recombination
KFE94_16700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFE94_16710	COG2304	oxidoreductase activity
KFE94_16820	COG2814	Major facilitator Superfamily
KFE94_16830	COG0628	permease
KFE94_16855	COG1611	Belongs to the LOG family
KFE94_16860	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KFE94_16865	COG5002	protein histidine kinase activity
KFE94_16900	COG1012	belongs to the aldehyde dehydrogenase family
KFE94_16960	COG3279	Response regulator of the LytR AlgR family
KFE94_16985	COG0519	Catalyzes the synthesis of GMP from XMP
KFE94_17020	COG1522	sequence-specific DNA binding
KFE94_17095	COG0668	transmembrane transport
KFE94_17125	COG1309	transcriptional regulator
KFE94_17150	COG3012	SEC-C Motif Domain Protein
KFE94_17160	COG3275	phosphorelay sensor kinase activity
KFE94_17180	COG2205	protein histidine kinase activity
KFE94_17195	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFE94_17195	COG1136	(ABC) transporter
KFE94_17235	COG0210	DNA helicase
KFE94_17290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFE94_17305	COG4191	Histidine kinase
KFE94_17310	COG2204	response regulator
KFE94_17320	COG1136	(ABC) transporter
KFE94_17320	COG0577	efflux transmembrane transporter activity
KFE94_17325	COG0577	efflux transmembrane transporter activity
KFE94_17325	COG1136	(ABC) transporter
KFE94_17360	COG3128	pkhd-type hydroxylase
KFE94_17405	COG2824	Alkylphosphonate utilization operon protein PhnA
KFE94_17420	COG3279	Response regulator of the LytR AlgR family
KFE94_17450	COG3275	phosphorelay sensor kinase activity
KFE94_17455	COG3279	Response regulator of the LytR AlgR family
KFE94_17465	COG2356	endonuclease I
KFE94_17515	COG2003	Belongs to the UPF0758 family
KFE94_17575	COG3757	hydrolase, family 25
KFE94_17580	COG0859	PFAM glycosyl transferase family 9
KFE94_17610	COG3279	Response regulator of the LytR AlgR family
KFE94_17635	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KFE94_17640	COG1690	Belongs to the RtcB family
KFE94_17660	COG3279	Response regulator of the LytR AlgR family
KFE94_17670	COG3279	Response regulator of the LytR AlgR family
KFE94_17740	COG1842	Phage shock protein A
KFE94_17750	COG1396	sequence-specific DNA binding
KFE94_17755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFE94_17760	COG3275	phosphorelay sensor kinase activity
KFE94_17765	COG3279	Response regulator of the LytR AlgR family
KFE94_17865	COG4638	Rieske (2fe-2S)
KFE94_17870	COG0783	Belongs to the Dps family
KFE94_17880	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
KFE94_17910	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFE94_17930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KFE94_17960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFE94_17965	COG2081	HI0933 family
KFE94_17975	COG1280	lysine exporter protein (LysE YggA)
KFE94_17985	COG1234	tRNA 3'-trailer cleavage
KFE94_17995	COG0540	Belongs to the ATCase OTCase family
KFE94_18000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
KFE94_18030	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFE94_18040	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFE94_18050	COG2890	protein-(glutamine-N5) methyltransferase activity
KFE94_18055	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFE94_18055	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFE94_18065	COG1739	Uncharacterized protein family UPF0029
KFE94_18075	COG0824	Thioesterase