locus-tag	class	description
KFE69_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFE69_00010	COG0592	DNA-directed DNA polymerase activity
KFE69_00020	COG0531	amino acid
KFE69_00025	COG0134	indole-3-glycerol-phosphate synthase activity
KFE69_00030	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KFE69_00055	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
KFE69_00070	COG1028	Short-chain dehydrogenase reductase Sdr
KFE69_00095	COG0384	phenazine biosynthesis protein PhzF
KFE69_00130	COG0488	(ABC) transporter
KFE69_00140	COG0488	(ABC) transporter
KFE69_00150	COG2814	Major facilitator Superfamily
KFE69_00155	COG0583	DNA-binding transcription factor activity
KFE69_00165	COG4206	TonB-dependent receptor
KFE69_00235	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFE69_00245	COG2027	D-alanyl-D-alanine carboxypeptidase
KFE69_00270	COG0444	Belongs to the ABC transporter superfamily
KFE69_00275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFE69_00280	COG0601	transmembrane transport
KFE69_00290	COG0668	transmembrane transport
KFE69_00305	COG1472	Belongs to the glycosyl hydrolase 3 family
KFE69_00315	COG0583	DNA-binding transcription factor activity
KFE69_00335	COG1028	Short-chain dehydrogenase reductase Sdr
KFE69_00340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFE69_00405	COG0471	metal ion transport
KFE69_00405	COG3273	potassium ion transport
KFE69_00435	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFE69_00480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFE69_00490	COG0859	PFAM glycosyl transferase family 9
KFE69_00505	COG0582	viral genome integration into host DNA
KFE69_00555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KFE69_00580	COG3239	Fatty acid desaturase
KFE69_00585	COG0477	Major facilitator Superfamily
KFE69_00590	COG1846	Transcriptional regulator
KFE69_00605	COG0477	Major facilitator Superfamily
KFE69_00610	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFE69_00645	COG3264	Mechanosensitive ion channel
KFE69_00645	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
KFE69_00660	COG0189	ligase activity
KFE69_00670	COG4067	protein conserved in archaea
KFE69_00670	COG0189	ligase activity
KFE69_00680	COG0656	L-ascorbic acid biosynthetic process
KFE69_00685	COG2814	Major facilitator Superfamily
KFE69_00795	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KFE69_00810	COG0598	Magnesium transport protein CorA
KFE69_00830	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KFE69_00840	COG0724	RNA recognition motif
KFE69_00850	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFE69_00855	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFE69_00940	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFE69_00945	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFE69_00955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFE69_00995	COG1120	ATPase activity
KFE69_01000	COG0019	diaminopimelate decarboxylase activity
KFE69_01025	COG4772	TonB-dependent receptor
KFE69_01030	COG0811	peptide transport
KFE69_01075	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFE69_01085	COG1231	oxidoreductase activity
KFE69_01090	COG3386	PFAM SMP-30 Gluconolaconase
KFE69_01115	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFE69_01125	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFE69_01135	COG1166	arginine decarboxylase activity
KFE69_01145	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KFE69_01150	COG0602	queuosine metabolic process
KFE69_01160	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFE69_01175	COG1012	belongs to the aldehyde dehydrogenase family
KFE69_01190	COG1183	phosphatidylcholine synthase activity
KFE69_01200	COG2011	ABC-type metal ion transport system permease component
KFE69_01210	COG0826	peptidase U32
KFE69_01225	COG2095	MarC family integral membrane protein
KFE69_01230	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFE69_01235	COG1294	oxidase, subunit
KFE69_01245	COG0589	response to stress
KFE69_01255	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFE69_01275	COG0281	malic enzyme
KFE69_01315	COG3243	poly(R)-hydroxyalkanoic acid synthase
KFE69_01355	COG0124	histidyl-tRNA synthetase
KFE69_01375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KFE69_01385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KFE69_01395	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFE69_01410	COG0281	malic enzyme
KFE69_01450	COG3023	N-Acetylmuramoyl-L-alanine amidase
KFE69_01455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KFE69_01460	COG0477	Major facilitator Superfamily
KFE69_01465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFE69_01495	COG0271	Belongs to the BolA IbaG family
KFE69_01510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFE69_01515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFE69_01520	COG1127	ABC transporter
KFE69_01530	COG0047	phosphoribosylformylglycinamidine synthase activity
KFE69_01530	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KFE69_01535	COG4680	protein conserved in bacteria
KFE69_01560	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KFE69_01565	COG1250	3-hydroxyacyl-CoA dehydrogenase
KFE69_01565	COG1024	Enoyl-CoA hydratase
KFE69_01570	COG0183	Belongs to the thiolase family
KFE69_01585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFE69_01600	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KFE69_01610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFE69_01615	COG0051	transcription antitermination factor activity, RNA binding
KFE69_01620	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KFE69_01625	COG0088	Forms part of the polypeptide exit tunnel
KFE69_01630	COG0089	rRNA binding
KFE69_01635	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFE69_01640	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KFE69_01650	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KFE69_01655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KFE69_01660	COG0255	Belongs to the universal ribosomal protein uL29 family
KFE69_01665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFE69_01670	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KFE69_01675	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFE69_01680	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFE69_01685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFE69_01690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KFE69_01695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
KFE69_01700	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KFE69_01710	COG1841	ribosomal large subunit assembly
KFE69_01715	COG0200	Binds to the 23S rRNA
KFE69_01720	COG0201	protein transport
KFE69_01725	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KFE69_01730	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KFE69_01735	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KFE69_01745	COG0202	RNA polymerase activity
KFE69_01755	COG0477	Major facilitator Superfamily
KFE69_01760	COG1280	lysine exporter protein (LysE YggA)
KFE69_01770	COG0583	DNA-binding transcription factor activity
KFE69_01795	COG0583	DNA-binding transcription factor activity
KFE69_01800	COG1335	isochorismatase
KFE69_01815	COG0181	hydroxymethylbilane synthase activity
KFE69_01825	COG0163	prenyltransferase activity
KFE69_01830	COG3621	Patatin-like phospholipase
KFE69_01845	COG1760	l-serine dehydratase
KFE69_01855	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KFE69_01865	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KFE69_01875	COG0328	RNA-DNA hybrid ribonuclease activity
KFE69_01890	COG1940	carbohydrate kinase activity
KFE69_01895	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFE69_01910	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFE69_01910	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFE69_01930	COG0658	competence protein
KFE69_01930	COG2333	competence protein COMEC
KFE69_01940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFE69_01950	COG1660	Displays ATPase and GTPase activities
KFE69_01960	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFE69_01970	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KFE69_01980	COG2271	Major facilitator Superfamily
KFE69_01985	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KFE69_01995	COG0582	viral genome integration into host DNA
KFE69_02015	COG0730	response to heat
KFE69_02020	COG3012	SEC-C Motif Domain Protein
KFE69_02020	COG3318	Belongs to the UPF0149 family
KFE69_02050	COG0346	lactoylglutathione lyase activity
KFE69_02060	COG0346	lactoylglutathione lyase activity
KFE69_02070	COG1733	regulation of RNA biosynthetic process
KFE69_02135	COG0642	Histidine kinase
KFE69_02140	COG2153	protein acetylation
KFE69_02150	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KFE69_02170	COG0357	Ribosomal RNA small subunit methyltransferase G
KFE69_02185	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFE69_02190	COG0546	phosphoglycolate phosphatase activity
KFE69_02225	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFE69_02230	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFE69_02240	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
KFE69_02245	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KFE69_02275	COG0347	Belongs to the P(II) protein family
KFE69_02285	COG0606	chelatase, subunit chli
KFE69_02300	COG0625	glutathione transferase activity
KFE69_02305	COG2814	Major facilitator Superfamily
KFE69_02310	COG2918	glutathione biosynthetic process
KFE69_02315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KFE69_02320	COG2217	Heavy metal translocating P-type atpase
KFE69_02365	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KFE69_02375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KFE69_02380	COG0459	protein refolding
KFE69_02415	COG1228	amidohydrolase
KFE69_02425	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KFE69_02430	COG2894	cell division
KFE69_02435	COG0850	regulation of cytokinetic process
KFE69_02445	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KFE69_02450	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KFE69_02455	COG1116	anion transmembrane transporter activity
KFE69_02470	COG0438	transferase activity, transferring glycosyl groups
KFE69_02475	COG0726	polysaccharide deacetylase
KFE69_02485	COG4251	negative regulation of phosphorylation
KFE69_02490	COG0784	Response regulator, receiver
KFE69_02495	COG4251	negative regulation of phosphorylation
KFE69_02505	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KFE69_02520	COG1610	YqeY-like protein
KFE69_02530	COG0629	single-stranded DNA binding
KFE69_02535	COG0268	Binds directly to 16S ribosomal RNA
KFE69_02540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFE69_02550	COG0009	L-threonylcarbamoyladenylate synthase
KFE69_02560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KFE69_02580	COG0235	Class ii aldolase
KFE69_02605	COG1324	tolerance protein
KFE69_02650	COG3104	oligopeptide transport
KFE69_02655	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
KFE69_02660	COG0494	nUDIX hydrolase
KFE69_02665	COG0174	glutamine synthetase
KFE69_02675	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFE69_02690	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
KFE69_02710	COG2818	Glycosylase
KFE69_02715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KFE69_02730	COG1278	Cold shock
KFE69_02745	COG0443	Heat shock 70 kDa protein
KFE69_02760	COG1218	3'(2'),5'-bisphosphate nucleotidase
KFE69_02765	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KFE69_02775	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KFE69_02780	COG2050	protein possibly involved in aromatic compounds catabolism
KFE69_02800	COG0284	orotidine-5'-phosphate decarboxylase activity
KFE69_02825	COG2814	Major facilitator Superfamily
KFE69_02830	COG0583	DNA-binding transcription factor activity
KFE69_02840	COG0425	Belongs to the sulfur carrier protein TusA family
KFE69_02845	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFE69_02850	COG0133	tryptophan synthase activity
KFE69_02855	COG0159	tryptophan synthase activity
KFE69_02865	COG3116	cell division
KFE69_02880	COG3220	belongs to the UPF0276 family
KFE69_02915	COG1028	Short-chain dehydrogenase reductase Sdr
KFE69_02920	COG0183	Belongs to the thiolase family
KFE69_02925	COG0489	protein tyrosine kinase activity
KFE69_02930	COG0717	Belongs to the dCTP deaminase family
KFE69_02955	COG1056	cytidyltransferase-related domain
KFE69_02955	COG1051	belongs to the nudix hydrolase family
KFE69_02970	COG3022	response to hydroperoxide
KFE69_02975	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFE69_02980	COG0254	rRNA binding
KFE69_03005	COG0582	viral genome integration into host DNA
KFE69_03095	COG1462	curli production assembly transport component CsgG
KFE69_03275	COG0210	DNA helicase
KFE69_03295	COG1611	Belongs to the LOG family
KFE69_03335	COG0360	Binds together with S18 to 16S ribosomal RNA
KFE69_03345	COG0359	binds to the 23S rRNA
KFE69_03360	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFE69_03380	COG1960	acyl-CoA dehydrogenase activity
KFE69_03395	COG0259	pyridoxamine-phosphate oxidase activity
KFE69_03400	COG0572	uridine kinase
KFE69_03405	COG1538	Outer membrane efflux protein
KFE69_03410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFE69_03415	COG0242	peptide deformylase activity
KFE69_03430	COG0242	peptide deformylase activity
KFE69_03455	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KFE69_03470	COG0531	amino acid
KFE69_03480	COG2267	carboxylic ester hydrolase activity
KFE69_03770	COG0237	dephospho-CoA kinase activity
KFE69_03795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFE69_03800	COG4536	flavin adenine dinucleotide binding
KFE69_03805	COG2922	Belongs to the Smg family
KFE69_03815	COG0758	DNA mediated transformation
KFE69_03820	COG1047	Peptidyl-prolyl cis-trans
KFE69_03825	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFE69_03835	COG1183	phosphatidylcholine synthase activity
KFE69_03840	COG0741	lytic transglycosylase activity
KFE69_03855	COG0719	Fe-S assembly protein
KFE69_03860	COG0396	ATPase activity
KFE69_03865	COG0719	Fe-S assembly protein
KFE69_03880	COG1137	ATPase activity
KFE69_03895	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KFE69_03920	COG0105	UTP biosynthetic process
KFE69_03945	COG1131	(ABC) transporter
KFE69_03950	COG0842	Transport permease protein
KFE69_03955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFE69_03955	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KFE69_03960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFE69_03965	COG2070	2-Nitropropane dioxygenase
KFE69_03985	COG1301	dicarboxylic acid transport
KFE69_04000	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KFE69_04005	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFE69_04010	COG0316	Belongs to the HesB IscA family
KFE69_04015	COG2151	metal-sulfur cluster biosynthetic enzyme
KFE69_04020	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KFE69_04025	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFE69_04040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFE69_04045	COG0443	Heat shock 70 kDa protein
KFE69_04050	COG0484	heat shock protein binding
KFE69_04060	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KFE69_04075	COG2274	protein secretion by the type I secretion system
KFE69_04080	COG1132	(ABC) transporter
KFE69_04490	COG0018	arginyl-trna synthetase
KFE69_04505	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFE69_04510	COG1177	transmembrane transport
KFE69_04515	COG1176	ABC-type spermidine putrescine transport system, permease component I
KFE69_04520	COG3842	ATPase activity
KFE69_04525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KFE69_04525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KFE69_04565	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KFE69_04590	COG0156	8-amino-7-oxononanoate synthase activity
KFE69_04595	COG0745	RESPONSE REGULATOR receiver
KFE69_04600	COG2198	Histidine kinase
KFE69_04600	COG2205	protein histidine kinase activity
KFE69_04600	COG0784	Response regulator, receiver
KFE69_04610	COG0218	Necessary for normal cell division and for the maintenance of normal septation
KFE69_04625	COG0751	glycine-tRNA ligase activity
KFE69_04630	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
KFE69_04635	COG2137	regulation of response to DNA damage stimulus
KFE69_04645	COG2267	carboxylic ester hydrolase activity
KFE69_04685	COG2885	chlorophyll binding
KFE69_04715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFE69_04720	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFE69_04730	COG0534	Mate efflux family protein
KFE69_04740	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFE69_04745	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KFE69_04750	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFE69_04770	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KFE69_04780	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KFE69_04785	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFE69_04790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFE69_04795	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFE69_04805	COG0477	Major facilitator Superfamily
KFE69_04810	COG0798	PFAM Bile acid sodium symporter
KFE69_04820	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KFE69_04825	COG0772	Belongs to the SEDS family
KFE69_04830	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFE69_04845	COG0586	Pfam SNARE associated Golgi protein
KFE69_04870	COG0288	reversible hydration of carbon dioxide
KFE69_04885	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFE69_04890	COG2205	protein histidine kinase activity
KFE69_04900	COG0745	RESPONSE REGULATOR receiver
KFE69_04905	COG0228	four-way junction DNA binding
KFE69_04910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFE69_04915	COG0336	Belongs to the RNA methyltransferase TrmD family
KFE69_04925	COG4974	Belongs to the 'phage' integrase family
KFE69_04940	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFE69_04950	COG0697	spore germination
KFE69_04960	COG0525	valine-tRNA ligase activity
KFE69_04965	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KFE69_04990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFE69_04995	COG2814	Major facilitator Superfamily
KFE69_05010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFE69_05015	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KFE69_05025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFE69_05025	COG0519	Catalyzes the synthesis of GMP from XMP
KFE69_05055	COG3093	addiction module antidote protein HigA
KFE69_05075	COG0156	8-amino-7-oxononanoate synthase activity
KFE69_05080	COG0596	Alpha beta hydrolase
KFE69_05080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFE69_05080	COG2226	methyltransferase
KFE69_05085	COG2226	methyltransferase
KFE69_05100	COG2337	Toxic component of a toxin-antitoxin (TA) module
KFE69_05105	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFE69_05105	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFE69_05110	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFE69_05120	COG3979	chitinase
KFE69_05150	COG5464	transposase or invertase
KFE69_05175	COG2814	Major facilitator Superfamily
KFE69_05185	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFE69_05185	COG0596	Alpha beta hydrolase
KFE69_05205	COG2271	Major facilitator Superfamily
KFE69_05210	COG0531	amino acid
KFE69_05225	COG2866	Carboxypeptidase
KFE69_05255	COG0156	8-amino-7-oxononanoate synthase activity
KFE69_05270	COG0745	RESPONSE REGULATOR receiver
KFE69_05275	COG2205	protein histidine kinase activity
KFE69_05295	COG2197	response regulator
KFE69_05325	COG1028	Short-chain dehydrogenase reductase Sdr
KFE69_05330	COG3104	oligopeptide transport
KFE69_05405	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
KFE69_05410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KFE69_05480	COG0583	DNA-binding transcription factor activity
KFE69_05490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KFE69_05495	COG4215	(ABC) transporter
KFE69_05535	COG0730	response to heat
KFE69_05540	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFE69_05600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KFE69_05615	COG2914	Belongs to the UPF0125 (RnfH) family
KFE69_05645	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFE69_05675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KFE69_05685	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
KFE69_05700	COG3451	type IV secretory pathway VirB4
KFE69_05720	COG2948	multi-organism process
KFE69_05740	COG4962	Type ii secretion system protein e
KFE69_05745	COG0252	asparaginase activity
KFE69_05760	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFE69_05775	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFE69_05780	COG0733	neurotransmitter:sodium symporter activity
KFE69_05785	COG2814	Major facilitator Superfamily
KFE69_05790	COG0445	tRNA wobble uridine modification
KFE69_05805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFE69_05825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KFE69_05835	COG0625	glutathione transferase activity
KFE69_05900	COG1396	sequence-specific DNA binding
KFE69_05910	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
KFE69_05930	COG0582	viral genome integration into host DNA
KFE69_05940	COG0202	RNA polymerase activity
KFE69_05950	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFE69_05995	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFE69_06005	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFE69_06020	COG0482	sulfurtransferase activity
KFE69_06030	COG2835	tetraacyldisaccharide 4'-kinase activity
KFE69_06050	COG0626	cystathionine gamma-synthase activity
KFE69_06060	COG0028	Belongs to the TPP enzyme family
KFE69_06075	COG1696	Membrane protein involved in D-alanine export
KFE69_06085	COG0318	PFAM AMP-dependent synthetase and ligase
KFE69_06090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFE69_06110	COG2814	Major facilitator Superfamily
KFE69_06130	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KFE69_06160	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFE69_06180	COG3577	Aspartyl protease
KFE69_06185	COG1686	Belongs to the peptidase S11 family
KFE69_06240	COG0730	response to heat
KFE69_06245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KFE69_06265	COG1127	ABC transporter
KFE69_06270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFE69_06290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFE69_06305	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KFE69_06310	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KFE69_06315	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KFE69_06330	COG2814	Major facilitator Superfamily
KFE69_06340	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KFE69_06345	COG0778	Nitroreductase
KFE69_06365	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFE69_06370	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KFE69_06385	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KFE69_06405	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KFE69_06430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFE69_06440	COG0825	malonyl-CoA metabolic process
KFE69_06455	COG0531	amino acid
KFE69_06460	COG1979	alcohol dehydrogenase
KFE69_06475	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KFE69_06485	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KFE69_06490	COG1702	phosphate starvation-inducible protein PhoH
KFE69_06495	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFE69_06500	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KFE69_06505	COG4988	ABC transporter
KFE69_06515	COG1509	lysine 2,3-aminomutase activity
KFE69_06520	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFE69_06525	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KFE69_06530	COG2199	diguanylate cyclase activity
KFE69_06530	COG2202	Pas domain
KFE69_06530	COG2200	EAL domain
KFE69_06540	COG0584	glycerophosphoryl diester phosphodiesterase
KFE69_06545	COG3240	lipase activity
KFE69_06550	COG1404	Belongs to the peptidase S8 family
KFE69_06575	COG0589	response to stress
KFE69_06580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFE69_06620	COG0189	ligase activity
KFE69_06625	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
KFE69_06635	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFE69_06635	COG0512	Glutamine amidotransferase of anthranilate synthase
KFE69_06640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFE69_06645	COG0477	Major facilitator Superfamily
KFE69_06660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KFE69_06670	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFE69_06690	COG3713	MltA-interacting MipA family protein
KFE69_06720	COG1643	Atp-dependent helicase
KFE69_06750	COG0742	ribosomal rna small subunit methyltransferase
KFE69_06755	COG0612	Peptidase, M16
KFE69_06760	COG0612	Peptidase, M16
KFE69_06765	COG0795	lipopolysaccharide-transporting ATPase activity
KFE69_06770	COG0795	lipopolysaccharide-transporting ATPase activity
KFE69_06775	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFE69_06785	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFE69_06790	COG0084	hydrolase, TatD family'
KFE69_06910	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
KFE69_06920	COG0686	Belongs to the AlaDH PNT family
KFE69_06930	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KFE69_06945	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
KFE69_06950	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFE69_06950	COG0574	Belongs to the PEP-utilizing enzyme family
KFE69_06980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFE69_06985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFE69_06990	COG0066	3-isopropylmalate dehydratase activity
KFE69_06995	COG0473	3-isopropylmalate dehydrogenase activity
KFE69_07015	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KFE69_07020	COG0084	hydrolase, TatD family'
KFE69_07030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFE69_07085	COG2814	Major facilitator Superfamily
KFE69_07125	COG1115	amino acid carrier protein
KFE69_07145	COG0095	Lipoate-protein ligase
KFE69_07150	COG1686	Belongs to the peptidase S11 family
KFE69_07160	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KFE69_07165	COG1185	polyribonucleotide nucleotidyltransferase activity
KFE69_07190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFE69_07195	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFE69_07205	COG1530	ribonuclease E activity
KFE69_07210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFE69_07220	COG0753	catalase activity
KFE69_07345	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFE69_07350	COG0363	glucosamine-6-phosphate deaminase activity
KFE69_07355	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFE69_07375	COG0431	NADPH-dependent FMN reductase
KFE69_07380	COG1194	a g-specific adenine glycosylase
KFE69_07385	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFE69_07395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFE69_07400	COG0285	dihydrofolate synthase activity
KFE69_07405	COG0802	atpase or kinase
KFE69_07410	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFE69_07430	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KFE69_07555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KFE69_07570	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KFE69_07575	COG0509	glycine decarboxylation via glycine cleavage system
KFE69_07600	COG0776	regulation of translation
KFE69_07610	COG0583	DNA-binding transcription factor activity
KFE69_07615	COG0028	Belongs to the TPP enzyme family
KFE69_07625	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFE69_07635	COG0129	dihydroxy-acid dehydratase activity
KFE69_07665	COG0740	serine-type endopeptidase activity
KFE69_07670	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFE69_07670	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KFE69_07680	COG1297	OPT oligopeptide transporter protein
KFE69_07695	COG0415	Belongs to the DNA photolyase family
KFE69_07720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFE69_07730	COG0463	Glycosyl transferase, family 2
KFE69_07735	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KFE69_07740	COG0456	acetyltransferase
KFE69_07740	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KFE69_07745	COG3012	SEC-C Motif Domain Protein
KFE69_07760	COG3239	Fatty acid desaturase
KFE69_07790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KFE69_07795	COG0318	PFAM AMP-dependent synthetase and ligase
KFE69_07800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KFE69_07815	COG2814	Major facilitator Superfamily
KFE69_07840	COG0628	permease
KFE69_07870	COG0477	Major facilitator Superfamily
KFE69_07875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFE69_07895	COG0686	Belongs to the AlaDH PNT family
KFE69_07900	COG0009	L-threonylcarbamoyladenylate synthase
KFE69_07905	COG2917	probably involved in intracellular septation
KFE69_07910	COG0531	amino acid
KFE69_07925	COG1741	Belongs to the pirin family
KFE69_07970	COG1028	Short-chain dehydrogenase reductase Sdr
KFE69_07985	COG0778	Nitroreductase
KFE69_07995	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KFE69_07995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KFE69_08030	COG0604	alcohol dehydrogenase
KFE69_08035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFE69_08040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KFE69_08070	COG1090	epimerase
KFE69_08080	COG2252	PERMEase
KFE69_08095	COG1773	rubredoxin
KFE69_08105	COG0121	glutamine amidotransferase
KFE69_08125	COG1063	alcohol dehydrogenase
KFE69_08130	COG0156	8-amino-7-oxononanoate synthase activity
KFE69_08145	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KFE69_08150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFE69_08155	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFE69_08160	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFE69_08175	COG0204	Acyl-transferase
KFE69_08185	COG1136	(ABC) transporter
KFE69_08190	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFE69_08195	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KFE69_08200	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KFE69_08205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFE69_08210	COG0037	tRNA processing
KFE69_08235	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFE69_08260	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KFE69_08265	COG1845	cytochrome c oxidase, subunit III
KFE69_08270	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KFE69_08300	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KFE69_08315	COG1151	hydroxylamine reductase activity
KFE69_08365	COG0438	transferase activity, transferring glycosyl groups
KFE69_08370	COG0512	Glutamine amidotransferase of anthranilate synthase
KFE69_08390	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KFE69_08400	COG1028	Short-chain dehydrogenase reductase Sdr
KFE69_08425	COG2890	protein-(glutamine-N5) methyltransferase activity
KFE69_08430	COG0215	cysteine-tRNA ligase activity
KFE69_08440	COG3104	oligopeptide transport
KFE69_08450	COG0504	CTP synthase activity
KFE69_08460	COG0456	acetyltransferase
KFE69_08500	COG2814	Major facilitator Superfamily
KFE69_08510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KFE69_08520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KFE69_08575	COG2814	Major facilitator Superfamily
KFE69_08580	COG2816	NAD+ diphosphatase activity
KFE69_08585	COG0859	PFAM glycosyl transferase family 9
KFE69_08600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KFE69_08650	COG0814	amino acid
KFE69_08675	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFE69_08690	COG4804	nuclease activity
KFE69_08810	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFE69_08815	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KFE69_08830	COG0625	glutathione transferase activity
KFE69_08840	COG0179	Fumarylacetoacetate (FAA) hydrolase
KFE69_08845	COG0814	amino acid
KFE69_08860	COG0859	PFAM glycosyl transferase family 9
KFE69_08865	COG0438	transferase activity, transferring glycosyl groups
KFE69_08865	COG0297	glycogen (starch) synthase activity
KFE69_08880	COG1322	Protein conserved in bacteria
KFE69_08885	COG0752	glycyl-tRNA synthetase alpha subunit
KFE69_08890	COG0666	response to abiotic stimulus
KFE69_08920	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KFE69_08925	COG0511	ligase activity, forming carbon-carbon bonds
KFE69_08930	COG0439	Biotin carboxylase
KFE69_08935	COG2264	protein methyltransferase activity
KFE69_08940	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFE69_08945	COG0138	bifunctional purine biosynthesis protein purh
KFE69_08950	COG0837	glucose binding
KFE69_08955	COG4536	flavin adenine dinucleotide binding
KFE69_09020	COG0469	pyruvate kinase activity
KFE69_09025	COG0126	phosphoglycerate kinase activity
KFE69_09030	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFE69_09045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFE69_09055	COG0300	oxidoreductase activity
KFE69_09075	COG0531	amino acid
KFE69_09105	COG2154	pterin-4-alpha-carbinolamine dehydratase
KFE69_09120	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KFE69_09140	COG0494	nUDIX hydrolase
KFE69_09145	COG0457	Tetratricopeptide repeat
KFE69_09145	COG0515	serine threonine protein kinase
KFE69_09155	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFE69_09165	COG0318	PFAM AMP-dependent synthetase and ligase
KFE69_09165	COG0204	Acyl-transferase
KFE69_09200	COG0405	Gamma-glutamyltransferase
KFE69_09205	COG2921	Belongs to the UPF0250 family
KFE69_09210	COG0321	lipoyl(octanoyl) transferase activity
KFE69_09240	COG4221	oxidoreductase activity
KFE69_09250	COG0038	chloride channel
KFE69_09255	COG0531	amino acid
KFE69_09275	COG0330	HflC and HflK could
KFE69_09280	COG0330	HflC and HflK could
KFE69_09285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFE69_09295	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFE69_09300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFE69_09310	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KFE69_09315	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFE69_09320	COG0740	serine-type endopeptidase activity
KFE69_09335	COG0248	Ppx GppA phosphatase
KFE69_09350	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KFE69_09355	COG2920	part of a sulfur-relay system
KFE69_09380	COG2184	nucleotidyltransferase activity
KFE69_09395	COG0028	Belongs to the TPP enzyme family
KFE69_09405	COG1984	allophanate hydrolase subunit 2
KFE69_09415	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KFE69_09430	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KFE69_09440	COG2974	May be involved in recombination
KFE69_09445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KFE69_09450	COG1272	protein, Hemolysin III
KFE69_09455	COG0424	maF-like protein
KFE69_09465	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFE69_09475	COG1487	ribonuclease activity
KFE69_09500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFE69_09540	COG0556	nucleotide-excision repair
KFE69_09545	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFE69_09555	COG0589	response to stress
KFE69_09590	COG1294	oxidase, subunit
KFE69_09600	COG2985	domain, Protein
KFE69_09620	COG1902	pentaerythritol trinitrate reductase activity
KFE69_09630	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
KFE69_09640	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
KFE69_09655	COG0309	Hydrogenase expression formation protein (HypE)
KFE69_09665	COG0298	carbon dioxide binding
KFE69_09680	COG0375	protein maturation
KFE69_09700	COG0857	belongs to the CobB CobQ family
KFE69_09700	COG0280	phosphate acetyltransferase
KFE69_09710	COG1982	Orn Lys Arg decarboxylase major
KFE69_09715	COG0531	amino acid
KFE69_09755	COG0814	amino acid
KFE69_09760	COG0501	Belongs to the peptidase M48B family
KFE69_09765	COG1704	LemA family
KFE69_09775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KFE69_09785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFE69_09790	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFE69_09800	COG0590	tRNA wobble adenosine to inosine editing
KFE69_09855	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KFE69_09860	COG1435	thymidine kinase activity
KFE69_09900	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFE69_09905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFE69_09910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFE69_09915	COG3079	Belongs to the UPF0149 family
KFE69_09925	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFE69_09975	COG0210	DNA helicase
KFE69_09995	COG1199	ATP-dependent helicase activity
KFE69_10000	COG0730	response to heat
KFE69_10005	COG0583	DNA-binding transcription factor activity
KFE69_10050	COG0633	Ferredoxin
KFE69_10055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFE69_10060	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFE69_10065	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KFE69_10080	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KFE69_10085	COG1566	PFAM secretion protein HlyD family protein
KFE69_10095	COG0436	Aminotransferase
KFE69_10110	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KFE69_10115	COG0833	amino acid
KFE69_10125	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KFE69_10155	COG2814	Major facilitator Superfamily
KFE69_10160	COG1309	transcriptional regulator
KFE69_10195	COG0513	Belongs to the DEAD box helicase family
KFE69_10200	COG0745	RESPONSE REGULATOR receiver
KFE69_10225	COG2805	Type II/IV secretion system protein
KFE69_10255	COG1162	GTPase activity
KFE69_10260	COG1381	Involved in DNA repair and RecF pathway recombination
KFE69_10270	COG1104	cysteine desulfurase activity
KFE69_10330	COG4232	protein-disulfide reductase activity
KFE69_10345	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KFE69_10350	COG1918	ferrous iron import across plasma membrane
KFE69_10360	COG0277	FAD linked oxidase domain protein
KFE69_10360	COG0247	lactate metabolic process
KFE69_10385	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFE69_10405	COG1695	Transcriptional regulator
KFE69_10440	COG0575	Belongs to the CDS family
KFE69_10450	COG0233	cytoplasmic translational termination
KFE69_10460	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFE69_10470	COG0024	Methionine aminopeptidase
KFE69_10495	COG0542	response to heat
KFE69_10515	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFE69_10520	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFE69_10535	COG0776	regulation of translation
KFE69_10540	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KFE69_10550	COG0730	response to heat
KFE69_10555	COG2226	methyltransferase
KFE69_10575	COG0497	DNA recombination
KFE69_10580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFE69_10600	COG3719	Belongs to the RNase T2 family
KFE69_10620	COG2878	Part of a membrane complex involved in electron transport
KFE69_10625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFE69_10635	COG1566	PFAM secretion protein HlyD family protein
KFE69_10645	COG2814	Major facilitator Superfamily
KFE69_10655	COG0670	Belongs to the BI1 family
KFE69_10665	COG2923	Belongs to the DsrF TusC family
KFE69_10680	COG1566	PFAM secretion protein HlyD family protein
KFE69_10685	COG0113	porphobilinogen synthase activity
KFE69_10690	COG1534	Rna-binding protein
KFE69_10695	COG0470	DNA polymerase III
KFE69_10700	COG0616	signal peptide processing
KFE69_10705	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFE69_10705	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFE69_10710	COG0625	glutathione transferase activity
KFE69_10725	COG1121	(ABC) transporter
KFE69_10740	COG1271	oxidase subunit
KFE69_10745	COG1294	oxidase, subunit
KFE69_10760	COG0326	Molecular chaperone. Has ATPase activity
KFE69_10810	COG0531	amino acid
KFE69_10820	COG3956	TIGRFAM MazG family protein
KFE69_10825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFE69_10830	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFE69_10840	COG0300	oxidoreductase activity
KFE69_10845	COG0564	pseudouridine synthase activity
KFE69_10850	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KFE69_10865	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFE69_10870	COG3104	oligopeptide transport
KFE69_10875	COG1663	tetraacyldisaccharide 4'-kinase activity
KFE69_10885	COG0617	tRNA 3'-terminal CCA addition
KFE69_10895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFE69_10900	COG1519	Transferase
KFE69_10905	COG0142	geranyltranstransferase activity
KFE69_10910	COG5001	Diguanylate cyclase
KFE69_10915	COG0569	domain protein
KFE69_10920	COG2096	Adenosyltransferase
KFE69_10925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KFE69_10930	COG1214	PFAM Peptidase M22, glycoprotease
KFE69_10935	COG2814	Major facilitator Superfamily
KFE69_10945	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFE69_10950	COG2971	BadF BadG BcrA BcrD
KFE69_10955	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
KFE69_11000	COG0814	amino acid
KFE69_11020	COG1678	Uncharacterized ACR, COG1678
KFE69_11035	COG0339	signal peptide processing
KFE69_11040	COG1994	Peptidase M50
KFE69_11060	COG1121	(ABC) transporter
KFE69_11065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KFE69_11075	COG0402	S-adenosylhomocysteine deaminase activity
KFE69_11120	COG3655	Transcriptional regulator
KFE69_11165	COG3243	poly(R)-hydroxyalkanoic acid synthase
KFE69_11175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFE69_11185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFE69_11190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFE69_11195	COG1862	Preprotein translocase
KFE69_11200	COG0343	queuine tRNA-ribosyltransferase activity
KFE69_11220	COG0557	exoribonuclease II activity
KFE69_11225	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KFE69_11230	COG0571	ribonuclease III activity
KFE69_11235	COG0681	Belongs to the peptidase S26 family
KFE69_11260	COG2195	Cleaves the N-terminal amino acid of tripeptides
KFE69_11280	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KFE69_11295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFE69_11305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFE69_11310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFE69_11315	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KFE69_11330	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFE69_11335	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KFE69_11365	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KFE69_11380	COG0024	Methionine aminopeptidase
KFE69_11390	COG2925	Exonuclease
KFE69_11395	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
KFE69_11400	COG1560	Kdo2-lipid A biosynthetic process
KFE69_11410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFE69_11415	COG0659	secondary active sulfate transmembrane transporter activity
KFE69_11425	COG1012	belongs to the aldehyde dehydrogenase family
KFE69_11500	COG0330	HflC and HflK could
KFE69_11510	COG1217	gtp-binding protein TYPA
KFE69_11530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFE69_11535	COG0142	geranyltranstransferase activity
KFE69_11555	COG0071	Belongs to the small heat shock protein (HSP20) family
KFE69_11570	COG0668	transmembrane transport
KFE69_11605	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFE69_11635	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
KFE69_11655	COG2226	methyltransferase
KFE69_11660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KFE69_11665	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KFE69_11675	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KFE69_11685	COG0398	Pfam SNARE associated Golgi protein
KFE69_11690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFE69_11720	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFE69_11725	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KFE69_11725	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KFE69_11735	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFE69_11745	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KFE69_11750	COG0217	transcriptional regulatory protein
KFE69_11775	COG2197	response regulator
KFE69_11785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFE69_11790	COG0531	amino acid
KFE69_11795	COG0793	Belongs to the peptidase S41A family
KFE69_11800	COG0776	regulation of translation
KFE69_11805	COG0072	phenylalanine-tRNA ligase activity
KFE69_11820	COG0494	nUDIX hydrolase
KFE69_11830	COG0673	inositol 2-dehydrogenase activity
KFE69_11835	COG1082	Xylose isomerase domain protein TIM barrel
KFE69_11840	COG3962	Belongs to the TPP enzyme family
KFE69_11845	COG3718	enzyme involved in inositol metabolism
KFE69_11850	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFE69_11855	COG0673	inositol 2-dehydrogenase activity
KFE69_11860	COG2814	Major facilitator Superfamily
KFE69_11865	COG2271	Major facilitator Superfamily
KFE69_11905	COG0657	acetylesterase activity
KFE69_11925	COG1605	Chorismate mutase
KFE69_11925	COG0287	Prephenate dehydrogenase
KFE69_11980	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KFE69_11985	COG0045	succinate-CoA ligase (ADP-forming) activity
KFE69_11995	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KFE69_12025	COG0477	Major facilitator Superfamily
KFE69_12035	COG0583	DNA-binding transcription factor activity
KFE69_12055	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFE69_12060	COG1494	fructose-1,6-bisphosphatase
KFE69_12070	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KFE69_12085	COG1902	pentaerythritol trinitrate reductase activity
KFE69_12085	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFE69_12100	COG1683	Conserved Protein
KFE69_12115	COG0745	RESPONSE REGULATOR receiver
KFE69_12120	COG2205	protein histidine kinase activity
KFE69_12135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFE69_12140	COG0477	Major facilitator Superfamily
KFE69_12155	COG0463	Glycosyl transferase, family 2
KFE69_12160	COG0187	DNA topoisomerase II activity
KFE69_12165	COG2030	dehydratase
KFE69_12185	COG0450	alkyl hydroperoxide reductase
KFE69_12200	COG0735	belongs to the Fur family
KFE69_12245	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFE69_12255	COG2271	Major facilitator Superfamily
KFE69_12265	COG1943	Transposase
KFE69_12270	COG0477	Major facilitator Superfamily
KFE69_12320	COG0424	maF-like protein
KFE69_12325	COG2814	Major facilitator Superfamily
KFE69_12335	COG0436	Aminotransferase
KFE69_12345	COG2999	glutathione oxidoreductase activity
KFE69_12360	COG0196	riboflavin kinase activity
KFE69_12365	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KFE69_12380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFE69_12385	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFE69_12425	COG2969	positive regulation of protein catabolic process
KFE69_12430	COG0625	glutathione transferase activity
KFE69_12440	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KFE69_12460	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KFE69_12470	COG0492	ferredoxin-NADP+ reductase activity
KFE69_12485	COG0438	transferase activity, transferring glycosyl groups
KFE69_12490	COG2223	nitrite transmembrane transporter activity
KFE69_12510	COG1475	DNA binding
KFE69_12515	COG1192	Involved in chromosome partitioning
KFE69_12525	COG0450	alkyl hydroperoxide reductase
KFE69_12535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFE69_12540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFE69_12550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KFE69_12555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFE69_12565	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KFE69_12570	COG1399	metal-binding, possibly nucleic acid-binding protein
KFE69_12575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFE69_12580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFE69_12605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFE69_12610	COG0601	transmembrane transport
KFE69_12615	COG2271	Major facilitator Superfamily
KFE69_12630	COG2072	flavoprotein involved in K transport
KFE69_12650	COG2814	Major facilitator Superfamily
KFE69_12670	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KFE69_12675	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFE69_12680	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KFE69_12685	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KFE69_12690	COG1054	Belongs to the UPF0176 family
KFE69_12695	COG0583	DNA-binding transcription factor activity
KFE69_12710	COG1596	polysaccharide export
KFE69_12730	COG0583	DNA-binding transcription factor activity
KFE69_12735	COG2855	membrane
KFE69_12745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFE69_12780	COG0135	phosphoribosylanthranilate isomerase activity
KFE69_12785	COG0443	Heat shock 70 kDa protein
KFE69_12795	COG0167	dihydroorotate dehydrogenase activity
KFE69_12835	COG0488	(ABC) transporter
KFE69_12850	COG1846	Transcriptional regulator
KFE69_12860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KFE69_12875	COG0085	RNA polymerase activity
KFE69_12895	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFE69_12905	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KFE69_12915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KFE69_12940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFE69_12985	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFE69_13005	COG0745	RESPONSE REGULATOR receiver
KFE69_13015	COG0789	Transcriptional regulator
KFE69_13030	COG0488	(ABC) transporter
KFE69_13055	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KFE69_13065	COG0552	protein localization to endoplasmic reticulum
KFE69_13075	COG0318	PFAM AMP-dependent synthetase and ligase
KFE69_13085	COG0069	glutamate synthase activity
KFE69_13090	COG1295	ribonuclease BN
KFE69_13095	COG0861	Integral membrane protein TerC family
KFE69_13110	COG0582	viral genome integration into host DNA
KFE69_13145	COG0235	Class ii aldolase
KFE69_13150	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KFE69_13195	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFE69_13195	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFE69_13200	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFE69_13225	COG1028	Short-chain dehydrogenase reductase Sdr
KFE69_13235	COG2211	Major facilitator Superfamily
KFE69_13245	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFE69_13260	COG5002	protein histidine kinase activity
KFE69_13265	COG0745	RESPONSE REGULATOR receiver
KFE69_13280	COG0352	thiamine-phosphate diphosphorylase activity
KFE69_13300	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KFE69_13305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFE69_13305	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFE69_13320	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFE69_13425	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KFE69_13430	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KFE69_13440	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KFE69_13445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFE69_13470	COG0195	Participates in both transcription termination and antitermination
KFE69_13470	COG2251	uridine kinase activity
KFE69_13475	COG0779	Required for maturation of 30S ribosomal subunits
KFE69_13505	COG1088	dTDP-glucose 4,6-dehydratase activity
KFE69_13550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFE69_13555	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KFE69_13560	COG0662	Cupin 2, conserved barrel domain protein
KFE69_13560	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KFE69_13575	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFE69_13595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KFE69_13650	COG0438	transferase activity, transferring glycosyl groups
KFE69_13660	COG0438	transferase activity, transferring glycosyl groups
KFE69_13670	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFE69_13685	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KFE69_13690	COG1007	ATP synthesis coupled electron transport
KFE69_13705	COG0713	ATP synthesis coupled electron transport
KFE69_13720	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KFE69_13725	COG1034	ATP synthesis coupled electron transport
KFE69_13735	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KFE69_13740	COG0649	NAD binding
KFE69_13745	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFE69_13750	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFE69_13755	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFE69_13785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFE69_13795	COG0542	response to heat
KFE69_13800	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KFE69_13805	COG0302	gtp cyclohydrolase
KFE69_13820	COG2945	thiolester hydrolase activity
KFE69_13835	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFE69_13850	COG0477	Major facilitator Superfamily
KFE69_13855	COG0114	fumarate hydratase activity
KFE69_13860	COG1309	transcriptional regulator
KFE69_13900	COG2205	protein histidine kinase activity
KFE69_13910	COG1074	ATP-dependent DNA helicase activity
KFE69_13915	COG3104	oligopeptide transport
KFE69_13920	COG2205	protein histidine kinase activity
KFE69_13920	COG3437	response regulator, receiver
KFE69_13920	COG3850	Histidine kinase
KFE69_13920	COG4999	Histidine kinase
KFE69_13925	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KFE69_13940	COG4251	negative regulation of phosphorylation
KFE69_13940	COG5001	Diguanylate cyclase
KFE69_13940	COG2203	Gaf domain
KFE69_13940	COG3706	GGDEF domain
KFE69_13945	COG2890	protein-(glutamine-N5) methyltransferase activity
KFE69_13960	COG0545	Peptidyl-prolyl cis-trans isomerase
KFE69_13970	COG0708	Exodeoxyribonuclease III
KFE69_13985	COG0573	inorganic phosphate transmembrane transporter activity
KFE69_13990	COG0581	inorganic phosphate transmembrane transporter activity
KFE69_14000	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFE69_14005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFE69_14010	COG0569	domain protein
KFE69_14035	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KFE69_14040	COG0706	membrane insertase activity
KFE69_14045	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KFE69_14050	COG0594	ribonuclease P activity
KFE69_14055	COG0230	Belongs to the bacterial ribosomal protein bL34 family