D521_1139 048719f00506825420046c224f446214 527 SUPERFAMILY SSF52821 14 120 4.19E-21 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1139 048719f00506825420046c224f446214 527 Gene3D G3DSA:3.40.250.10 126 233 4.7E-22 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1139 048719f00506825420046c224f446214 527 SUPERFAMILY SSF52821 255 351 8.77E-20 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1139 048719f00506825420046c224f446214 527 Pfam PF00581 Rhodanese-like domain 387 468 8.1E-5 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1139 048719f00506825420046c224f446214 527 Pfam PF00581 Rhodanese-like domain 14 101 4.3E-8 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1139 048719f00506825420046c224f446214 527 Pfam PF00581 Rhodanese-like domain 130 224 3.1E-9 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1139 048719f00506825420046c224f446214 527 SMART SM00450 265 362 0.033 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1139 048719f00506825420046c224f446214 527 SMART SM00450 7 104 1.7E-11 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1139 048719f00506825420046c224f446214 527 SMART SM00450 377 472 2.2E-5 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1139 048719f00506825420046c224f446214 527 SMART SM00450 130 228 3.7E-7 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1139 048719f00506825420046c224f446214 527 Gene3D G3DSA:3.40.250.10 261 351 1.7E-18 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1139 048719f00506825420046c224f446214 527 SUPERFAMILY SSF52821 106 234 3.93E-29 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1139 048719f00506825420046c224f446214 527 SUPERFAMILY SSF52821 371 523 3.8E-26 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1139 048719f00506825420046c224f446214 527 Gene3D G3DSA:3.40.250.10 14 109 3.9E-19 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1139 048719f00506825420046c224f446214 527 Gene3D G3DSA:3.40.250.10 373 479 1.2E-18 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1706 9d0a8cf06ca6f2fd6138833fd969ba28 294 Gene3D G3DSA:3.90.550.10 3 294 2.2E-94 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1706 9d0a8cf06ca6f2fd6138833fd969ba28 294 Pfam PF00483 Nucleotidyl transferase 15 270 8.4E-29 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 D521_1706 9d0a8cf06ca6f2fd6138833fd969ba28 294 SUPERFAMILY SSF53448 9 281 3.76E-66 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1706 9d0a8cf06ca6f2fd6138833fd969ba28 294 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 269 7.0E-115 T 14-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 D521_1799 4fd24d12289249a3cd54548123eb77ac 217 Pfam PF02798 Glutathione S-transferase, N-terminal domain 1 75 5.5E-18 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 D521_1799 4fd24d12289249a3cd54548123eb77ac 217 SUPERFAMILY SSF47616 82 211 8.91E-19 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily D521_1799 4fd24d12289249a3cd54548123eb77ac 217 Gene3D G3DSA:3.40.30.10 2 89 2.2E-24 T 14-10-2018 D521_1799 4fd24d12289249a3cd54548123eb77ac 217 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 4 210 6.1E-62 T 14-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 D521_1799 4fd24d12289249a3cd54548123eb77ac 217 SUPERFAMILY SSF52833 2 86 4.57E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1799 4fd24d12289249a3cd54548123eb77ac 217 Gene3D G3DSA:1.20.1050.10 90 216 9.8E-36 T 14-10-2018 D521_0934 07e6a520314133a70995e408bd113e14 186 Gene3D G3DSA:3.40.50.1110 1 180 3.5E-66 T 14-10-2018 IPR036514 SGNH hydrolase superfamily D521_0934 07e6a520314133a70995e408bd113e14 186 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 4 163 1.7E-21 T 14-10-2018 IPR013830 SGNH hydrolase-type esterase domain D521_0934 07e6a520314133a70995e408bd113e14 186 SUPERFAMILY SSF52266 2 176 8.86E-47 T 14-10-2018 D521_0654 04f8b81277c7d0fac113828a10039508 400 Gene3D G3DSA:2.40.50.100 77 111 3.4E-10 T 14-10-2018 D521_0654 04f8b81277c7d0fac113828a10039508 400 Gene3D G3DSA:1.10.287.470 203 253 3.3E-14 T 14-10-2018 D521_0654 04f8b81277c7d0fac113828a10039508 400 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 299 323 1.0E-32 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 D521_0654 04f8b81277c7d0fac113828a10039508 400 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 379 399 1.0E-32 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 D521_0654 04f8b81277c7d0fac113828a10039508 400 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 266 287 1.0E-32 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 D521_0654 04f8b81277c7d0fac113828a10039508 400 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 48 71 1.0E-32 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 D521_0654 04f8b81277c7d0fac113828a10039508 400 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 323 346 1.0E-32 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 D521_0654 04f8b81277c7d0fac113828a10039508 400 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 364 379 1.0E-32 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 D521_0654 04f8b81277c7d0fac113828a10039508 400 SUPERFAMILY SSF111369 68 151 9.68E-8 T 14-10-2018 D521_0654 04f8b81277c7d0fac113828a10039508 400 Gene3D G3DSA:2.40.30.170 66 76 3.4E-10 T 14-10-2018 D521_0654 04f8b81277c7d0fac113828a10039508 400 Pfam PF13533 Biotin-lipoyl like 78 114 9.5E-9 T 14-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain D521_0654 04f8b81277c7d0fac113828a10039508 400 Gene3D G3DSA:2.40.50.100 254 290 3.3E-14 T 14-10-2018 D521_0654 04f8b81277c7d0fac113828a10039508 400 Gene3D G3DSA:1.10.287.470 112 172 3.4E-10 T 14-10-2018 D521_0654 04f8b81277c7d0fac113828a10039508 400 Gene3D G3DSA:2.40.30.170 291 376 3.3E-14 T 14-10-2018 D521_0654 04f8b81277c7d0fac113828a10039508 400 Pfam PF13437 HlyD family secretion protein 254 367 2.0E-16 T 14-10-2018 D521_2117 84407c1ede88c990705ad2a5000e9436 54 Pfam PF01809 Haemolytic domain 2 46 7.6E-20 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor D521_2117 84407c1ede88c990705ad2a5000e9436 54 SMART SM01234 1 47 1.2E-9 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor D521_2117 84407c1ede88c990705ad2a5000e9436 54 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 2 53 1.2E-18 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor D521_2117 84407c1ede88c990705ad2a5000e9436 54 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 2 47 8.0E-12 T 14-10-2018 IPR002696 Putative membrane protein insertion efficiency factor D521_1125 2dedd34479e8ca1794e4856b0c84dddb 637 SUPERFAMILY SSF52540 12 194 5.72E-31 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1125 2dedd34479e8ca1794e4856b0c84dddb 637 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 36 54 1.3E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_1125 2dedd34479e8ca1794e4856b0c84dddb 637 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 15 35 1.3E-5 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_1125 2dedd34479e8ca1794e4856b0c84dddb 637 Pfam PF02421 Ferrous iron transport protein B 15 172 4.5E-52 T 14-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 D521_1125 2dedd34479e8ca1794e4856b0c84dddb 637 Pfam PF07664 Ferrous iron transport protein B C terminus 416 469 2.9E-15 T 14-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 D521_1125 2dedd34479e8ca1794e4856b0c84dddb 637 Pfam PF07670 Nucleoside recognition 305 396 3.0E-11 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 D521_1125 2dedd34479e8ca1794e4856b0c84dddb 637 Pfam PF07670 Nucleoside recognition 474 606 5.8E-26 T 14-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 D521_1125 2dedd34479e8ca1794e4856b0c84dddb 637 Gene3D G3DSA:3.40.50.300 13 215 2.1E-38 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 SUPERFAMILY SSF52317 1 187 2.2E-56 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.3E-13 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.3E-13 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.3E-13 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 Pfam PF00117 Glutamine amidotransferase class-I 4 185 6.9E-58 T 14-10-2018 IPR017926 Glutamine amidotransferase D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 3.3E-84 T 14-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.1E-36 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00097 Anthranilate synthase component II signature 164 177 4.1E-36 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.1E-36 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.1E-36 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.1E-36 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.1E-36 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 3.0E-5 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 3.0E-5 T 14-10-2018 D521_0148 c80b78f7a3d1a45b478f34bbf8f4c22c 188 Gene3D G3DSA:3.40.50.880 1 187 3.9E-64 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_1109 432455062ba966fed4a5301afd354023 997 Pfam PF12705 PD-(D/E)XK nuclease superfamily 708 993 1.5E-31 T 14-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type D521_1109 432455062ba966fed4a5301afd354023 997 SUPERFAMILY SSF52540 319 680 2.12E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1295 727d941041cee742b18ee104fd072cab 344 Gene3D G3DSA:3.40.50.300 108 176 3.4E-12 T 14-10-2018 D521_1295 727d941041cee742b18ee104fd072cab 344 Pfam PF13538 UvrD-like helicase C-terminal domain 296 342 6.1E-7 T 14-10-2018 IPR027785 UvrD-like helicase C-terminal domain D521_1295 727d941041cee742b18ee104fd072cab 344 Gene3D G3DSA:1.10.10.160 77 107 3.4E-12 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily D521_1295 727d941041cee742b18ee104fd072cab 344 Pfam PF00580 UvrD/REP helicase N-terminal domain 93 176 1.3E-9 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 D521_1295 727d941041cee742b18ee104fd072cab 344 SUPERFAMILY SSF52540 81 343 9.81E-33 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1295 727d941041cee742b18ee104fd072cab 344 Gene3D G3DSA:3.40.50.300 177 344 3.3E-10 T 14-10-2018 D521_0518 57e1449506f1b53068f3221a63d5c5b2 510 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 461 5.6E-101 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit D521_0518 57e1449506f1b53068f3221a63d5c5b2 510 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 465 4.7E-83 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 D521_1994 3bcbf44b01a804138c86b5fa1e0e73fd 491 SUPERFAMILY SSF53448 1 265 1.19E-52 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1994 3bcbf44b01a804138c86b5fa1e0e73fd 491 Gene3D G3DSA:2.160.10.10 241 468 2.9E-66 T 14-10-2018 D521_1994 3bcbf44b01a804138c86b5fa1e0e73fd 491 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 465 38.973 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 D521_1994 3bcbf44b01a804138c86b5fa1e0e73fd 491 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 1 466 2.9E-173 T 14-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 D521_1994 3bcbf44b01a804138c86b5fa1e0e73fd 491 SUPERFAMILY SSF51161 268 451 3.84E-50 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily D521_1994 3bcbf44b01a804138c86b5fa1e0e73fd 491 Gene3D G3DSA:3.90.550.10 1 240 1.2E-57 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1994 3bcbf44b01a804138c86b5fa1e0e73fd 491 Pfam PF12804 MobA-like NTP transferase domain 4 153 1.7E-17 T 14-10-2018 IPR025877 MobA-like NTP transferase D521_1994 3bcbf44b01a804138c86b5fa1e0e73fd 491 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 313 344 9.2E-6 T 14-10-2018 IPR001451 Hexapeptide repeat D521_1994 3bcbf44b01a804138c86b5fa1e0e73fd 491 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 408 442 1.1E-6 T 14-10-2018 IPR001451 Hexapeptide repeat D521_1006 6706f486e33cd8f4ec07110874cbad62 469 Gene3D G3DSA:3.30.499.20 4 286 7.3E-98 T 14-10-2018 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 Pfam PF00330 Aconitase family (aconitate hydratase) 7 460 7.4E-160 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 469 60.696 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 468 3.0E-238 T 14-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 PRINTS PR00415 Aconitase family signature 108 116 7.5E-50 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 PRINTS PR00415 Aconitase family signature 195 208 7.5E-50 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 PRINTS PR00415 Aconitase family signature 286 300 7.5E-50 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 PRINTS PR00415 Aconitase family signature 133 148 7.5E-50 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 PRINTS PR00415 Aconitase family signature 119 132 7.5E-50 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 PRINTS PR00415 Aconitase family signature 343 354 7.5E-50 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 PRINTS PR00415 Aconitase family signature 402 415 7.5E-50 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 PRINTS PR00415 Aconitase family signature 209 222 7.5E-50 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 PRINTS PR00415 Aconitase family signature 82 95 7.5E-50 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 SUPERFAMILY SSF53732 1 468 6.15E-164 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 Gene3D G3DSA:3.30.499.10 324 469 6.0E-49 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 D521_1006 6706f486e33cd8f4ec07110874cbad62 469 ProSitePatterns PS01244 Aconitase family signature 2. 402 415 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 D521_1132 39e2fab3bddd3e66d1846405c4e050b2 140 Pfam PF13673 Acetyltransferase (GNAT) domain 21 139 2.6E-19 T 14-10-2018 IPR000182 GNAT domain D521_1132 39e2fab3bddd3e66d1846405c4e050b2 140 Gene3D G3DSA:3.40.630.30 5 140 2.1E-39 T 14-10-2018 D521_1132 39e2fab3bddd3e66d1846405c4e050b2 140 SUPERFAMILY SSF55729 6 139 1.77E-38 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_1770 beddd62413aa3233dea0a1b80ca98842 348 Gene3D G3DSA:2.40.10.240 67 166 8.4E-113 T 14-10-2018 D521_1770 beddd62413aa3233dea0a1b80ca98842 348 Pfam PF02547 Queuosine biosynthesis protein 3 340 8.3E-128 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 D521_1770 beddd62413aa3233dea0a1b80ca98842 348 SUPERFAMILY SSF111337 1 340 2.49E-129 T 14-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 D521_1770 beddd62413aa3233dea0a1b80ca98842 348 Gene3D G3DSA:3.40.1780.10 14 339 8.4E-113 T 14-10-2018 D521_1770 beddd62413aa3233dea0a1b80ca98842 348 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 341 45.584 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 D521_1770 beddd62413aa3233dea0a1b80ca98842 348 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 340 1.8E-128 T 14-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 D521_1112 24024605377257d192d10b73fc4d435f 114 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1112 24024605377257d192d10b73fc4d435f 114 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 80 4.4E-22 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1112 24024605377257d192d10b73fc4d435f 114 SUPERFAMILY SSF143800 1 80 8.24E-23 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1112 24024605377257d192d10b73fc4d435f 114 PRINTS PR01249 Ribosomal protein L31 signature 2 19 3.9E-18 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1112 24024605377257d192d10b73fc4d435f 114 PRINTS PR01249 Ribosomal protein L31 signature 60 78 3.9E-18 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1112 24024605377257d192d10b73fc4d435f 114 PRINTS PR01249 Ribosomal protein L31 signature 45 60 3.9E-18 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1112 24024605377257d192d10b73fc4d435f 114 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.941 T 14-10-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1112 24024605377257d192d10b73fc4d435f 114 Pfam PF01197 Ribosomal protein L31 1 79 7.2E-30 T 14-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1112 24024605377257d192d10b73fc4d435f 114 Gene3D G3DSA:2.30.170.50 1 83 7.3E-27 T 14-10-2018 D521_1727 ecb5a9fca5e7b54c2c12f86373b32092 403 SUPERFAMILY SSF52507 2 182 1.31E-61 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 D521_1727 ecb5a9fca5e7b54c2c12f86373b32092 403 SUPERFAMILY SSF102645 176 401 4.19E-61 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 D521_1727 ecb5a9fca5e7b54c2c12f86373b32092 403 Pfam PF02441 Flavoprotein 7 178 2.8E-42 T 14-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 D521_1727 ecb5a9fca5e7b54c2c12f86373b32092 403 Gene3D G3DSA:3.40.50.10300 186 403 2.1E-62 T 14-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 D521_1727 ecb5a9fca5e7b54c2c12f86373b32092 403 Gene3D G3DSA:3.40.50.1950 1 185 1.2E-56 T 14-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 D521_1727 ecb5a9fca5e7b54c2c12f86373b32092 403 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 186 375 2.7E-58 T 14-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 D521_1727 ecb5a9fca5e7b54c2c12f86373b32092 403 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 6 399 4.7E-129 T 14-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 D521_1054 786840cb91f1463108907340a3f341cd 322 SUPERFAMILY SSF51569 6 321 9.52E-104 T 14-10-2018 D521_1054 786840cb91f1463108907340a3f341cd 322 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 17 318 1.2E-92 T 14-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 D521_1054 786840cb91f1463108907340a3f341cd 322 TIGRFAM TIGR00874 talAB: transaldolase 7 321 5.7E-133 T 14-10-2018 IPR004730 Transaldolase type 1 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 D521_1054 786840cb91f1463108907340a3f341cd 322 Gene3D G3DSA:3.20.20.70 4 322 7.0E-128 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1054 786840cb91f1463108907340a3f341cd 322 ProSitePatterns PS00958 Transaldolase active site. 126 143 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 D521_1054 786840cb91f1463108907340a3f341cd 322 ProSitePatterns PS01054 Transaldolase signature 1. 34 42 - T 14-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 D521_0220 b4d6d9226c291bbc95f857182f748463 302 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 19 302 30.926 T 14-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 D521_0220 b4d6d9226c291bbc95f857182f748463 302 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 24 106 4.6E-23 T 14-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 D521_0220 b4d6d9226c291bbc95f857182f748463 302 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 21 285 8.7E-78 T 14-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 D521_0220 b4d6d9226c291bbc95f857182f748463 302 Gene3D G3DSA:3.40.50.720 132 264 1.5E-77 T 14-10-2018 D521_0220 b4d6d9226c291bbc95f857182f748463 302 SUPERFAMILY SSF51735 119 287 3.29E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0220 b4d6d9226c291bbc95f857182f748463 302 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 133 218 1.1E-8 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase D521_0220 b4d6d9226c291bbc95f857182f748463 302 Gene3D G3DSA:3.40.50.10860 22 283 1.5E-77 T 14-10-2018 D521_0220 b4d6d9226c291bbc95f857182f748463 302 SUPERFAMILY SSF53223 20 118 1.38E-30 T 14-10-2018 D521_0663 91807fdb34f504441d7c5808956ced20 239 SMART SM00448 10 122 2.3E-10 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_0663 91807fdb34f504441d7c5808956ced20 239 SUPERFAMILY SSF52172 10 140 5.69E-17 T 14-10-2018 IPR011006 CheY-like superfamily D521_0663 91807fdb34f504441d7c5808956ced20 239 Pfam PF00196 Bacterial regulatory proteins, luxR family 163 218 7.8E-11 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0663 91807fdb34f504441d7c5808956ced20 239 Gene3D G3DSA:3.40.50.12740 10 223 2.8E-40 T 14-10-2018 D521_0663 91807fdb34f504441d7c5808956ced20 239 Pfam PF00072 Response regulator receiver domain 12 122 3.4E-12 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_0663 91807fdb34f504441d7c5808956ced20 239 SUPERFAMILY SSF46894 155 221 9.52E-15 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 D521_0663 91807fdb34f504441d7c5808956ced20 239 SMART SM00421 160 219 1.4E-7 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1239 4cc6906dc94fe106e88be52553a5e7de 305 SUPERFAMILY SSF53850 91 303 5.43E-34 T 14-10-2018 D521_1239 4cc6906dc94fe106e88be52553a5e7de 305 Gene3D G3DSA:3.40.190.10 166 273 5.3E-55 T 14-10-2018 D521_1239 4cc6906dc94fe106e88be52553a5e7de 305 Pfam PF03466 LysR substrate binding domain 92 301 2.5E-30 T 14-10-2018 IPR005119 LysR, substrate-binding D521_1239 4cc6906dc94fe106e88be52553a5e7de 305 SUPERFAMILY SSF46785 5 115 9.35E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1239 4cc6906dc94fe106e88be52553a5e7de 305 Gene3D G3DSA:3.40.190.10 94 299 5.3E-55 T 14-10-2018 D521_1239 4cc6906dc94fe106e88be52553a5e7de 305 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 2.7E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_1239 4cc6906dc94fe106e88be52553a5e7de 305 Gene3D G3DSA:1.10.10.10 6 92 5.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1753 3c3e3b27eaa79512343411d857f87a8f 364 TIGRFAM TIGR00109 hemH: ferrochelatase 8 336 1.9E-94 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 D521_1753 3c3e3b27eaa79512343411d857f87a8f 364 SUPERFAMILY SSF53800 10 340 7.48E-107 T 14-10-2018 D521_1753 3c3e3b27eaa79512343411d857f87a8f 364 Gene3D G3DSA:3.40.50.1400 11 337 1.1E-99 T 14-10-2018 D521_1753 3c3e3b27eaa79512343411d857f87a8f 364 Pfam PF00762 Ferrochelatase 11 336 2.0E-114 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 D521_1753 3c3e3b27eaa79512343411d857f87a8f 364 Hamap MF_00323 Ferrochelatase [hemH]. 10 336 37.794 T 14-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 D521_1753 3c3e3b27eaa79512343411d857f87a8f 364 Gene3D G3DSA:3.40.50.1400 174 317 1.1E-99 T 14-10-2018 D521_0929 59f166b27ee1e79dadd3206ed4918703 445 SUPERFAMILY SSF109998 259 443 1.57E-42 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily D521_0929 59f166b27ee1e79dadd3206ed4918703 445 Gene3D G3DSA:3.10.50.40 150 257 1.3E-88 T 14-10-2018 D521_0929 59f166b27ee1e79dadd3206ed4918703 445 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 167 248 2.0E-12 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain D521_0929 59f166b27ee1e79dadd3206ed4918703 445 Hamap MF_00303 Trigger factor [tig]. 1 432 19.307 T 14-10-2018 IPR005215 Trigger factor GO:0015031 D521_0929 59f166b27ee1e79dadd3206ed4918703 445 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 274 425 1.3E-30 T 14-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 D521_0929 59f166b27ee1e79dadd3206ed4918703 445 Gene3D G3DSA:1.10.3120.10 116 431 1.3E-88 T 14-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 D521_0929 59f166b27ee1e79dadd3206ed4918703 445 Pfam PF05697 Bacterial trigger factor protein (TF) 1 142 1.2E-31 T 14-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 D521_0929 59f166b27ee1e79dadd3206ed4918703 445 TIGRFAM TIGR00115 tig: trigger factor 12 424 1.5E-117 T 14-10-2018 IPR005215 Trigger factor GO:0015031 D521_0929 59f166b27ee1e79dadd3206ed4918703 445 SUPERFAMILY SSF102735 1 130 2.09E-29 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 D521_0929 59f166b27ee1e79dadd3206ed4918703 445 PIRSF PIRSF003095 1 445 1.3E-110 T 14-10-2018 IPR005215 Trigger factor GO:0015031 D521_0929 59f166b27ee1e79dadd3206ed4918703 445 Gene3D G3DSA:3.30.70.1050 1 115 1.2E-25 T 14-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 D521_0929 59f166b27ee1e79dadd3206ed4918703 445 SUPERFAMILY SSF54534 88 251 1.04E-28 T 14-10-2018 D521_1014 0cfdfd6d67867ea1fbe760aa094a69f4 329 SUPERFAMILY SSF56327 160 328 4.94E-59 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 D521_1014 0cfdfd6d67867ea1fbe760aa094a69f4 329 Gene3D G3DSA:3.40.50.720 1 157 6.1E-60 T 14-10-2018 D521_1014 0cfdfd6d67867ea1fbe760aa094a69f4 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 160 322 1.4E-32 T 14-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 D521_1014 0cfdfd6d67867ea1fbe760aa094a69f4 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 328 55.86 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 D521_1014 0cfdfd6d67867ea1fbe760aa094a69f4 329 SUPERFAMILY SSF51735 4 158 1.11E-47 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1014 0cfdfd6d67867ea1fbe760aa094a69f4 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 322 1.3E-146 T 14-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 D521_1014 0cfdfd6d67867ea1fbe760aa094a69f4 329 PIRSF PIRSF000102 2 327 1.1E-66 T 14-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 D521_1014 0cfdfd6d67867ea1fbe760aa094a69f4 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 155 1.9E-37 T 14-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 D521_1014 0cfdfd6d67867ea1fbe760aa094a69f4 329 Gene3D G3DSA:3.90.110.10 158 329 3.7E-62 T 14-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 D521_0246 7fadbc054c45e89fdae610005152a563 221 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 33 221 34.296 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 D521_0246 7fadbc054c45e89fdae610005152a563 221 SUPERFAMILY SSF143456 34 221 3.79E-58 T 14-10-2018 D521_0246 7fadbc054c45e89fdae610005152a563 221 Pfam PF02622 Uncharacterized ACR, COG1678 44 208 5.0E-47 T 14-10-2018 IPR003774 Protein of unknown function UPF0301 D521_0246 7fadbc054c45e89fdae610005152a563 221 Gene3D G3DSA:3.40.1740.10 31 221 1.0E-62 T 14-10-2018 D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 429 3.4E-120 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 181 317 1.5E-43 T 14-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 PIRSF PIRSF000445 1 438 7.6E-140 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 334 429 1.4E-25 T 14-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 SUPERFAMILY SSF51735 172 325 6.84E-31 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 SUPERFAMILY SSF69075 331 430 4.45E-24 T 14-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 108 131 - T 14-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 429 28.391 T 14-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 Gene3D G3DSA:3.40.50.720 170 325 4.4E-38 T 14-10-2018 D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 165 5.7E-48 T 14-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 SUPERFAMILY SSF69742 1 167 8.89E-45 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 D521_0135 6a713ab857f6bfe0e5b02fa7a6f2bab3 438 Gene3D G3DSA:3.30.460.30 2 167 4.1E-53 T 14-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 D521_1159 5b9fbbf4fdbcfa0b27fdf822c9dbd277 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 6.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_1159 5b9fbbf4fdbcfa0b27fdf822c9dbd277 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 6.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_1159 5b9fbbf4fdbcfa0b27fdf822c9dbd277 315 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 6.1E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_1159 5b9fbbf4fdbcfa0b27fdf822c9dbd277 315 Pfam PF03466 LysR substrate binding domain 93 298 1.6E-44 T 14-10-2018 IPR005119 LysR, substrate-binding D521_1159 5b9fbbf4fdbcfa0b27fdf822c9dbd277 315 SUPERFAMILY SSF53850 93 300 3.08E-41 T 14-10-2018 D521_1159 5b9fbbf4fdbcfa0b27fdf822c9dbd277 315 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 65 3.1E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_1159 5b9fbbf4fdbcfa0b27fdf822c9dbd277 315 Gene3D G3DSA:3.40.190.10 96 292 4.9E-59 T 14-10-2018 D521_1159 5b9fbbf4fdbcfa0b27fdf822c9dbd277 315 Gene3D G3DSA:1.10.10.10 3 88 2.3E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1159 5b9fbbf4fdbcfa0b27fdf822c9dbd277 315 SUPERFAMILY SSF46785 5 115 8.52E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1159 5b9fbbf4fdbcfa0b27fdf822c9dbd277 315 Gene3D G3DSA:3.40.190.10 165 269 4.9E-59 T 14-10-2018 D521_1769 21df97fc1f262e44d7e92635a3514d63 695 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 20 666 2.8E-210 T 14-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 D521_1769 21df97fc1f262e44d7e92635a3514d63 695 Pfam PF00270 DEAD/DEAH box helicase 294 437 1.7E-17 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 D521_1769 21df97fc1f262e44d7e92635a3514d63 695 Gene3D G3DSA:3.40.50.300 460 632 2.2E-52 T 14-10-2018 D521_1769 21df97fc1f262e44d7e92635a3514d63 695 SMART SM00490 508 591 6.4E-20 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1769 21df97fc1f262e44d7e92635a3514d63 695 Gene3D G3DSA:3.40.50.300 213 453 2.4E-81 T 14-10-2018 D521_1769 21df97fc1f262e44d7e92635a3514d63 695 SUPERFAMILY SSF52540 455 657 1.5E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1769 21df97fc1f262e44d7e92635a3514d63 695 SMART SM00487 268 462 5.2E-31 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_1769 21df97fc1f262e44d7e92635a3514d63 695 Pfam PF17191 RecG wedge domain 9 156 1.3E-6 T 14-10-2018 IPR033454 RecG, wedge domain D521_1769 21df97fc1f262e44d7e92635a3514d63 695 SUPERFAMILY SSF52540 203 456 3.21E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1769 21df97fc1f262e44d7e92635a3514d63 695 Pfam PF00271 Helicase conserved C-terminal domain 485 590 2.4E-16 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1769 21df97fc1f262e44d7e92635a3514d63 695 SUPERFAMILY SSF50249 9 158 4.88E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1388 0e54076bd2ff23afb60dcc5fc3040ffe 390 Gene3D G3DSA:3.40.640.10 2 250 1.1E-87 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_1388 0e54076bd2ff23afb60dcc5fc3040ffe 390 PIRSF PIRSF000390 7 388 3.4E-103 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase D521_1388 0e54076bd2ff23afb60dcc5fc3040ffe 390 SUPERFAMILY SSF53383 10 386 3.7E-101 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_1388 0e54076bd2ff23afb60dcc5fc3040ffe 390 Gene3D G3DSA:3.90.1150.10 253 389 9.1E-29 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_1388 0e54076bd2ff23afb60dcc5fc3040ffe 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 19 380 5.5E-105 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase D521_1214 84ddb85811aab612666f984229accd93 274 Pfam PF04305 Protein of unknown function (DUF455) 15 260 1.7E-93 T 14-10-2018 IPR007402 Protein of unknown function DUF455 D521_1214 84ddb85811aab612666f984229accd93 274 SUPERFAMILY SSF47240 81 250 1.87E-12 T 14-10-2018 IPR009078 Ferritin-like superfamily D521_1214 84ddb85811aab612666f984229accd93 274 PIRSF PIRSF012318 1 272 3.1E-96 T 14-10-2018 IPR011197 Uncharacterised conserved protein UCP012318 D521_1071 7b09f74b428f4bb572d04d76ecf9ca9d 80 SUPERFAMILY SSF50182 9 71 5.45E-24 T 14-10-2018 IPR010920 LSM domain superfamily D521_1071 7b09f74b428f4bb572d04d76ecf9ca9d 80 Pfam PF17209 Hfq protein 9 70 1.1E-31 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 D521_1071 7b09f74b428f4bb572d04d76ecf9ca9d 80 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 9 66 8.6E-29 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 D521_1071 7b09f74b428f4bb572d04d76ecf9ca9d 80 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 2 66 27.612 T 14-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 D521_1071 7b09f74b428f4bb572d04d76ecf9ca9d 80 Gene3D G3DSA:2.30.30.100 2 79 9.9E-33 T 14-10-2018 D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 Pfam PF04408 Helicase associated domain (HA2) 444 541 8.4E-14 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 SMART SM00847 442 545 2.4E-29 T 14-10-2018 IPR007502 Helicase-associated domain GO:0004386 D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 Pfam PF11898 Domain of unknown function (DUF3418) 708 1357 5.4E-203 T 14-10-2018 IPR024590 RNA helicase HrpA, C-terminal D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 SMART SM00487 31 223 2.4E-26 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 Gene3D G3DSA:1.20.120.1080 427 540 6.0E-12 T 14-10-2018 D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 Pfam PF00270 DEAD/DEAH box helicase 39 193 9.7E-8 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 Pfam PF00271 Helicase conserved C-terminal domain 264 381 7.3E-9 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 Gene3D G3DSA:3.40.50.300 2 216 7.2E-74 T 14-10-2018 D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 23 1041 0.0 T 14-10-2018 IPR010222 RNA helicase HrpA GO:0004004 D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 Gene3D G3DSA:3.40.50.300 217 400 1.3E-51 T 14-10-2018 D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 SMART SM00490 284 382 2.5E-12 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 SUPERFAMILY SSF52540 31 553 2.48E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 SMART SM00382 49 348 1.6E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1050 1e7b3aa2fa4c3cea7320978dc5f4bff2 1360 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 609 693 1.3E-11 T 14-10-2018 IPR011709 Domain of unknown function DUF1605 D521_0545 70b2611b83419dcd676217b92f0e64e8 208 SMART SM00421 140 197 7.0E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0545 70b2611b83419dcd676217b92f0e64e8 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 194 2.8E-16 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0545 70b2611b83419dcd676217b92f0e64e8 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 2.7E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0545 70b2611b83419dcd676217b92f0e64e8 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 2.7E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0545 70b2611b83419dcd676217b92f0e64e8 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 2.7E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0545 70b2611b83419dcd676217b92f0e64e8 208 SUPERFAMILY SSF52172 6 160 9.82E-33 T 14-10-2018 IPR011006 CheY-like superfamily D521_0545 70b2611b83419dcd676217b92f0e64e8 208 Gene3D G3DSA:3.40.50.2300 1 137 1.9E-34 T 14-10-2018 D521_0545 70b2611b83419dcd676217b92f0e64e8 208 Gene3D G3DSA:1.10.10.10 138 200 1.3E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0545 70b2611b83419dcd676217b92f0e64e8 208 Pfam PF00072 Response regulator receiver domain 7 116 6.6E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_0545 70b2611b83419dcd676217b92f0e64e8 208 SUPERFAMILY SSF46894 140 202 1.13E-14 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 D521_0545 70b2611b83419dcd676217b92f0e64e8 208 SMART SM00448 5 116 4.7E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 SUPERFAMILY SSF50249 14 74 1.16E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 SUPERFAMILY SSF50249 116 615 7.71E-137 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 Gene3D G3DSA:2.40.50.140 618 714 2.1E-20 T 14-10-2018 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 TIGRFAM TIGR02063 RNase_R: ribonuclease R 15 522 1.0E-194 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 SMART SM00955 189 521 3.1E-175 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 SMART SM00357 15 74 3.8E-14 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 Hamap MF_01895 Ribonuclease R [rnr]. 2 698 53.641 T 14-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 ProSitePatterns PS01175 Ribonuclease II family signature. 488 512 - T 14-10-2018 IPR022966 Ribonuclease II/R, conserved site D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 Pfam PF08206 Ribonuclease B OB domain 16 73 2.3E-24 T 14-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 SMART SM00316 615 698 3.6E-15 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 SMART SM00316 10 71 7.9 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 Pfam PF00773 RNB domain 189 521 2.1E-101 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 Gene3D G3DSA:2.40.50.140 3 75 1.7E-19 T 14-10-2018 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 10 522 1.3E-166 T 14-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 Pfam PF00575 S1 RNA binding domain 616 696 1.1E-11 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_1058 d555d90024f1c0ac76f06614dc3b411b 800 SUPERFAMILY SSF50249 617 697 2.24E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_0645 e752ec296b69615b25e090aca8b84f02 276 Pfam PF00482 Type II secretion system (T2SS), protein F 132 260 2.9E-20 T 14-10-2018 IPR018076 Type II secretion system F domain D521_1806 bdfc69508af46a8c9e75ff6b63a7c742 364 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 10 213 8.9E-54 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 D521_1806 bdfc69508af46a8c9e75ff6b63a7c742 364 SUPERFAMILY SSF55821 12 216 9.77E-57 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily D521_1806 bdfc69508af46a8c9e75ff6b63a7c742 364 Pfam PF03481 Putative GTP-binding controlling metal-binding 234 351 2.0E-14 T 14-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain D521_1806 bdfc69508af46a8c9e75ff6b63a7c742 364 Gene3D G3DSA:3.40.50.11030 228 358 5.7E-10 T 14-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily D521_1806 bdfc69508af46a8c9e75ff6b63a7c742 364 PIRSF PIRSF004930 2 354 2.4E-95 T 14-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 D521_1806 bdfc69508af46a8c9e75ff6b63a7c742 364 Pfam PF01300 Telomere recombination 20 208 9.8E-52 T 14-10-2018 IPR006070 YrdC-like domain GO:0003725 D521_1806 bdfc69508af46a8c9e75ff6b63a7c742 364 Gene3D G3DSA:3.90.870.10 4 222 1.5E-73 T 14-10-2018 D521_0664 0047475f60d4a6835eff51fdbf363f93 924 SMART SM00267 741 922 6.1E-44 T 14-10-2018 IPR000160 GGDEF domain D521_0664 0047475f60d4a6835eff51fdbf363f93 924 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 749 920 1.4E-39 T 14-10-2018 IPR000160 GGDEF domain D521_0664 0047475f60d4a6835eff51fdbf363f93 924 Pfam PF13426 PAS domain 473 573 1.6E-8 T 14-10-2018 IPR000014 PAS domain D521_0664 0047475f60d4a6835eff51fdbf363f93 924 Gene3D G3DSA:3.30.450.40 598 748 4.6E-18 T 14-10-2018 IPR029016 GAF-like domain superfamily D521_0664 0047475f60d4a6835eff51fdbf363f93 924 SUPERFAMILY SSF109604 237 422 8.79E-34 T 14-10-2018 D521_0664 0047475f60d4a6835eff51fdbf363f93 924 SUPERFAMILY SSF55785 452 573 5.06E-21 T 14-10-2018 IPR035965 PAS domain superfamily D521_0664 0047475f60d4a6835eff51fdbf363f93 924 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 457 580 6.3E-19 T 14-10-2018 IPR000014 PAS domain D521_0664 0047475f60d4a6835eff51fdbf363f93 924 SMART SM00471 241 395 3.0E-9 T 14-10-2018 IPR003607 HD/PDEase domain D521_0664 0047475f60d4a6835eff51fdbf363f93 924 Gene3D G3DSA:3.30.450.20 452 573 1.1E-21 T 14-10-2018 D521_0664 0047475f60d4a6835eff51fdbf363f93 924 Pfam PF13185 GAF domain 618 740 3.5E-8 T 14-10-2018 IPR003018 GAF domain GO:0005515 D521_0664 0047475f60d4a6835eff51fdbf363f93 924 SUPERFAMILY SSF55073 757 920 7.22E-42 T 14-10-2018 IPR029787 Nucleotide cyclase D521_0664 0047475f60d4a6835eff51fdbf363f93 924 Gene3D G3DSA:1.10.3210.10 221 439 4.3E-72 T 14-10-2018 D521_0664 0047475f60d4a6835eff51fdbf363f93 924 Pfam PF00990 Diguanylate cyclase, GGDEF domain 752 918 2.4E-42 T 14-10-2018 IPR000160 GGDEF domain D521_0664 0047475f60d4a6835eff51fdbf363f93 924 Gene3D G3DSA:3.30.70.270 749 923 2.9E-51 T 14-10-2018 D521_0664 0047475f60d4a6835eff51fdbf363f93 924 SUPERFAMILY SSF55781 569 741 4.17E-19 T 14-10-2018 D521_0664 0047475f60d4a6835eff51fdbf363f93 924 SMART SM00091 461 528 6.6E-7 T 14-10-2018 IPR000014 PAS domain D521_0664 0047475f60d4a6835eff51fdbf363f93 924 Pfam PF01966 HD domain 247 385 1.2E-17 T 14-10-2018 IPR006674 HD domain D521_1135 7e0d4db2909bb51d3d7cb52bb6c20016 427 Hamap MF_00968 ATP-dependent RNA helicase RhlE [rhlE]. 1 424 49.371 T 14-10-2018 IPR028622 ATP-dependent RNA helicase RhlE GO:0004004|GO:0042255 D521_1135 7e0d4db2909bb51d3d7cb52bb6c20016 427 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site D521_1135 7e0d4db2909bb51d3d7cb52bb6c20016 427 SMART SM00490 258 339 4.0E-31 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1135 7e0d4db2909bb51d3d7cb52bb6c20016 427 Gene3D G3DSA:3.40.50.300 214 399 3.5E-49 T 14-10-2018 D521_1135 7e0d4db2909bb51d3d7cb52bb6c20016 427 Pfam PF00270 DEAD/DEAH box helicase 25 195 7.2E-51 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 D521_1135 7e0d4db2909bb51d3d7cb52bb6c20016 427 Pfam PF00271 Helicase conserved C-terminal domain 234 339 1.1E-28 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1135 7e0d4db2909bb51d3d7cb52bb6c20016 427 Gene3D G3DSA:3.40.50.300 1 210 3.9E-75 T 14-10-2018 D521_1135 7e0d4db2909bb51d3d7cb52bb6c20016 427 SMART SM00487 20 222 1.2E-55 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_1135 7e0d4db2909bb51d3d7cb52bb6c20016 427 SUPERFAMILY SSF52540 74 360 5.81E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 SUPERFAMILY SSF47203 232 387 2.58E-43 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 221 2.3E-20 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 Gene3D G3DSA:1.10.540.10 8 118 4.3E-24 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 Gene3D G3DSA:2.40.110.10 123 238 1.7E-34 T 14-10-2018 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 PIRSF PIRSF016578 136 197 0.26 T 14-10-2018 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 PIRSF PIRSF016578 5 100 3.2E-5 T 14-10-2018 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 PIRSF PIRSF016578 239 388 1.3E-4 T 14-10-2018 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 341 360 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 366 3.4E-32 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 SUPERFAMILY SSF56645 8 246 7.85E-59 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 118 3.1E-20 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 D521_1603 372ad8c7b42b2d41cfe6e77f3555d70f 389 Gene3D G3DSA:1.20.140.10 239 382 2.0E-35 T 14-10-2018 D521_1475 a7d383d2e71f99d5e0d68370558829f3 403 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 7 395 30.188 T 14-10-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 D521_1475 a7d383d2e71f99d5e0d68370558829f3 403 Gene3D G3DSA:1.25.40.10 44 181 2.1E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1475 a7d383d2e71f99d5e0d68370558829f3 403 Gene3D G3DSA:1.25.40.10 182 291 8.4E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1475 a7d383d2e71f99d5e0d68370558829f3 403 SUPERFAMILY SSF81901 47 256 3.66E-10 T 14-10-2018 D521_1608 befcbf8083761f529af28efa77280829 213 Pfam PF00392 Bacterial regulatory proteins, gntR family 4 65 4.6E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1608 befcbf8083761f529af28efa77280829 213 SMART SM00895 75 199 3.0E-18 T 14-10-2018 IPR011711 GntR, C-terminal D521_1608 befcbf8083761f529af28efa77280829 213 Pfam PF07729 FCD domain 82 198 3.8E-25 T 14-10-2018 IPR011711 GntR, C-terminal D521_1608 befcbf8083761f529af28efa77280829 213 SMART SM00345 7 65 2.8E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1608 befcbf8083761f529af28efa77280829 213 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 39 55 1.4E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1608 befcbf8083761f529af28efa77280829 213 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 25 39 1.4E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1608 befcbf8083761f529af28efa77280829 213 Gene3D G3DSA:1.10.10.10 1 66 1.7E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1608 befcbf8083761f529af28efa77280829 213 SUPERFAMILY SSF48008 81 202 2.33E-25 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal D521_1608 befcbf8083761f529af28efa77280829 213 Gene3D G3DSA:1.20.120.530 70 203 6.0E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal D521_1608 befcbf8083761f529af28efa77280829 213 SUPERFAMILY SSF46785 3 93 1.79E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1757 dc5b232371dc150cecce421c50da944e 939 SUPERFAMILY SSF81301 508 799 2.51E-61 T 14-10-2018 D521_1757 dc5b232371dc150cecce421c50da944e 939 Gene3D G3DSA:1.20.120.1510 456 544 2.8E-10 T 14-10-2018 D521_1757 dc5b232371dc150cecce421c50da944e 939 Gene3D G3DSA:1.20.120.330 271 436 2.2E-49 T 14-10-2018 D521_1757 dc5b232371dc150cecce421c50da944e 939 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 13 245 3.8E-61 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 D521_1757 dc5b232371dc150cecce421c50da944e 939 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 537 784 7.8E-55 T 14-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 D521_1757 dc5b232371dc150cecce421c50da944e 939 SUPERFAMILY SSF81593 274 432 3.61E-37 T 14-10-2018 D521_1757 dc5b232371dc150cecce421c50da944e 939 Gene3D G3DSA:1.20.120.330 799 935 7.5E-33 T 14-10-2018 D521_1757 dc5b232371dc150cecce421c50da944e 939 Pfam PF08335 GlnD PII-uridylyltransferase 813 905 1.9E-8 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 D521_1757 dc5b232371dc150cecce421c50da944e 939 Pfam PF08335 GlnD PII-uridylyltransferase 283 432 4.0E-42 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 D521_1757 dc5b232371dc150cecce421c50da944e 939 SUPERFAMILY SSF81301 8 272 1.85E-68 T 14-10-2018 D521_1757 dc5b232371dc150cecce421c50da944e 939 SUPERFAMILY SSF81593 802 933 1.65E-29 T 14-10-2018 D521_1757 dc5b232371dc150cecce421c50da944e 939 Gene3D G3DSA:3.30.460.100 545 798 2.4E-63 T 14-10-2018 D521_1757 dc5b232371dc150cecce421c50da944e 939 Gene3D G3DSA:3.30.460.100 15 255 1.6E-61 T 14-10-2018 D521_1757 dc5b232371dc150cecce421c50da944e 939 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 3 935 17.476 T 14-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 D521_1924 801488b5b8861dc6bc3077d77420da22 461 Pfam PF00675 Insulinase (Peptidase family M16) 42 185 7.6E-29 T 14-10-2018 IPR011765 Peptidase M16, N-terminal D521_1924 801488b5b8861dc6bc3077d77420da22 461 SUPERFAMILY SSF63411 251 444 9.33E-32 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 D521_1924 801488b5b8861dc6bc3077d77420da22 461 Gene3D G3DSA:3.30.830.10 249 444 5.0E-48 T 14-10-2018 D521_1924 801488b5b8861dc6bc3077d77420da22 461 Gene3D G3DSA:3.30.830.10 26 248 3.6E-79 T 14-10-2018 D521_1924 801488b5b8861dc6bc3077d77420da22 461 SUPERFAMILY SSF63411 28 234 1.29E-61 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 D521_1924 801488b5b8861dc6bc3077d77420da22 461 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 61 84 - T 14-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 D521_1924 801488b5b8861dc6bc3077d77420da22 461 Pfam PF05193 Peptidase M16 inactive domain 197 375 6.7E-29 T 14-10-2018 IPR007863 Peptidase M16, C-terminal D521_0040 61bbf4df665fe5267b7966a04f719606 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 6.6E-24 T 14-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 D521_0040 61bbf4df665fe5267b7966a04f719606 143 Gene3D G3DSA:3.30.1550.10 2 72 7.1E-35 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily D521_0040 61bbf4df665fe5267b7966a04f719606 143 Gene3D G3DSA:1.10.10.2720 73 143 1.6E-27 T 14-10-2018 D521_0040 61bbf4df665fe5267b7966a04f719606 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 31.168 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 D521_0040 61bbf4df665fe5267b7966a04f719606 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 7.5E-65 T 14-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0040 61bbf4df665fe5267b7966a04f719606 143 SUPERFAMILY SSF54747 3 73 1.96E-30 T 14-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily D521_0040 61bbf4df665fe5267b7966a04f719606 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 14-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0040 61bbf4df665fe5267b7966a04f719606 143 SMART SM00649 9 141 2.5E-84 T 14-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 D521_0040 61bbf4df665fe5267b7966a04f719606 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 4.8E-29 T 14-10-2018 IPR020784 Ribosomal protein L11, N-terminal D521_0040 61bbf4df665fe5267b7966a04f719606 143 SUPERFAMILY SSF46906 68 141 6.28E-27 T 14-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily D521_0040 61bbf4df665fe5267b7966a04f719606 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 2.0E-15 T 14-10-2018 D521_0941 e73cd8b9be25711f20f83ba581c7344e 287 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 16 277 4.3E-121 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 D521_0941 e73cd8b9be25711f20f83ba581c7344e 287 SUPERFAMILY SSF51569 4 277 1.74E-101 T 14-10-2018 D521_0941 e73cd8b9be25711f20f83ba581c7344e 287 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 11 278 52.196 T 14-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 D521_0941 e73cd8b9be25711f20f83ba581c7344e 287 Pfam PF00793 DAHP synthetase I family 11 270 1.4E-67 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 D521_0941 e73cd8b9be25711f20f83ba581c7344e 287 Gene3D G3DSA:3.20.20.70 5 281 1.2E-103 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 Pfam PF00512 His Kinase A (phospho-acceptor) domain 536 602 5.7E-11 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 SUPERFAMILY SSF158472 338 387 3.4E-9 T 14-10-2018 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 SUPERFAMILY SSF55874 595 749 7.86E-29 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 SUPERFAMILY SSF55785 388 444 2.85E-6 T 14-10-2018 IPR035965 PAS domain superfamily D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 SMART SM00387 642 765 3.0E-27 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 Pfam PF00672 HAMP domain 338 386 2.0E-10 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 Gene3D G3DSA:1.10.287.130 524 603 5.6E-12 T 14-10-2018 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 PIRSF PIRSF037532 7 769 1.5E-194 T 14-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 642 747 3.0E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 SUPERFAMILY SSF47384 531 607 5.69E-12 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 SMART SM00304 338 390 7.4E-11 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 Gene3D G3DSA:3.30.565.10 606 764 1.2E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 PRINTS PR00344 Bacterial sensor protein C-terminal signature 721 739 1.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 PRINTS PR00344 Bacterial sensor protein C-terminal signature 710 720 1.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 PRINTS PR00344 Bacterial sensor protein C-terminal signature 692 706 1.7E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 SMART SM00388 534 606 8.2E-12 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_2105 87d22a1ae26c1f79d6b0fda5790745df 769 Gene3D G3DSA:1.20.1480.50 306 396 8.1E-12 T 14-10-2018 D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 PIRSF PIRSF000171 1 563 5.3E-41 T 14-10-2018 D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 Gene3D G3DSA:1.20.58.100 418 531 1.8E-24 T 14-10-2018 D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 Gene3D G3DSA:3.50.50.60 9 403 1.9E-126 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 SUPERFAMILY SSF56425 232 353 6.43E-32 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 Pfam PF02910 Fumarate reductase flavoprotein C-term 444 565 1.3E-20 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 SUPERFAMILY SSF51905 5 414 9.98E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 Gene3D G3DSA:3.90.700.10 242 358 1.9E-126 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 SUPERFAMILY SSF46977 440 566 3.01E-30 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 Pfam PF00890 FAD binding domain 9 391 7.0E-74 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 3.9E-7 T 14-10-2018 D521_1336 635d63091c1c2c459f00b0c6a9059b20 572 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 3.9E-7 T 14-10-2018 D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 PRINTS PR00987 Glutamyl-tRNA synthetase signature 17 29 2.8E-15 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 PRINTS PR00987 Glutamyl-tRNA synthetase signature 215 223 2.8E-15 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 PRINTS PR00987 Glutamyl-tRNA synthetase signature 46 59 2.8E-15 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 PRINTS PR00987 Glutamyl-tRNA synthetase signature 199 209 2.8E-15 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 PRINTS PR00987 Glutamyl-tRNA synthetase signature 31 42 2.8E-15 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 14 303 1.5E-112 T 14-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 SUPERFAMILY SSF52374 14 271 1.6E-78 T 14-10-2018 D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 14 315 40.062 T 14-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 Gene3D G3DSA:3.40.50.620 89 247 4.6E-94 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 Gene3D G3DSA:3.40.50.620 15 310 4.6E-94 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0475 c69161fd9c4c8b859d7c22d95b9233bf 317 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 15 270 1.4E-45 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 D521_1490 f101d851c89e30a1d80823e1ec94fbf5 140 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 128 4.7E-7 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain D521_1490 f101d851c89e30a1d80823e1ec94fbf5 140 SUPERFAMILY SSF54593 6 130 2.69E-23 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase D521_1490 f101d851c89e30a1d80823e1ec94fbf5 140 Gene3D G3DSA:3.10.180.10 1 138 6.2E-37 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase D521_0081 2d38b6a2e36b29ccb2611dd6f77e7472 557 Gene3D G3DSA:3.40.30.10 429 555 1.6E-30 T 14-10-2018 D521_0081 2d38b6a2e36b29ccb2611dd6f77e7472 557 SUPERFAMILY SSF74863 24 143 5.89E-23 T 14-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily D521_0081 2d38b6a2e36b29ccb2611dd6f77e7472 557 Gene3D G3DSA:2.60.40.1250 21 150 1.9E-27 T 14-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily D521_0081 2d38b6a2e36b29ccb2611dd6f77e7472 557 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 202 403 5.4E-18 T 14-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 D521_0081 2d38b6a2e36b29ccb2611dd6f77e7472 557 Pfam PF13899 Thioredoxin-like 447 527 9.9E-13 T 14-10-2018 D521_0081 2d38b6a2e36b29ccb2611dd6f77e7472 557 SUPERFAMILY SSF52833 449 553 3.88E-22 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0081 2d38b6a2e36b29ccb2611dd6f77e7472 557 Pfam PF11412 Disulphide bond corrector protein DsbC 25 143 3.1E-24 T 14-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain D521_0607 ea8b3f45d45e19200bee0d820ff69bb6 277 Gene3D G3DSA:1.10.10.10 28 107 4.1E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0607 ea8b3f45d45e19200bee0d820ff69bb6 277 SUPERFAMILY SSF46785 110 185 3.05E-24 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0607 ea8b3f45d45e19200bee0d820ff69bb6 277 SUPERFAMILY SSF46785 31 107 7.34E-15 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0607 ea8b3f45d45e19200bee0d820ff69bb6 277 PIRSF PIRSF019345 235 276 440.0 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 D521_0607 ea8b3f45d45e19200bee0d820ff69bb6 277 PIRSF PIRSF019345 23 221 8.5E-55 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 D521_0607 ea8b3f45d45e19200bee0d820ff69bb6 277 Gene3D G3DSA:1.10.10.10 108 205 4.5E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0607 ea8b3f45d45e19200bee0d820ff69bb6 277 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 35 198 1.3E-31 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 D521_0607 ea8b3f45d45e19200bee0d820ff69bb6 277 Pfam PF04079 Segregation and condensation complex subunit ScpB 36 193 1.5E-48 T 14-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 D521_0715 ba4aea069d77ae177e5b1e397d659bc4 406 SMART SM00729 20 249 8.3E-55 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 D521_0715 ba4aea069d77ae177e5b1e397d659bc4 406 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 21 393 4.1E-117 T 14-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 D521_0715 ba4aea069d77ae177e5b1e397d659bc4 406 Gene3D G3DSA:3.80.30.20 5 332 1.5E-97 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe D521_0715 ba4aea069d77ae177e5b1e397d659bc4 406 Pfam PF04055 Radical SAM superfamily 25 203 1.2E-18 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 D521_0715 ba4aea069d77ae177e5b1e397d659bc4 406 SUPERFAMILY SSF102114 6 406 4.97E-109 T 14-10-2018 D521_0715 ba4aea069d77ae177e5b1e397d659bc4 406 Pfam PF06969 HemN C-terminal domain 333 395 1.4E-11 T 14-10-2018 IPR010723 HemN, C-terminal D521_0543 5f1d1fac1fe7b1594040556b50739571 162 SUPERFAMILY SSF110087 9 151 1.57E-47 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily D521_0543 5f1d1fac1fe7b1594040556b50739571 162 Gene3D G3DSA:2.60.40.1890 38 151 1.5E-39 T 14-10-2018 IPR036182 Copper chaperone PCuAC superfamily D521_0543 5f1d1fac1fe7b1594040556b50739571 162 Pfam PF04314 Copper chaperone PCu(A)C 35 142 2.6E-39 T 14-10-2018 IPR007410 Copper chaperone PCuAC D521_1886 f622d83b28426446be8154dfea664c57 152 Pfam PF00293 NUDIX domain 5 139 4.5E-20 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 D521_1886 f622d83b28426446be8154dfea664c57 152 Gene3D G3DSA:3.90.79.10 1 146 8.4E-36 T 14-10-2018 D521_1886 f622d83b28426446be8154dfea664c57 152 SUPERFAMILY SSF55811 3 143 7.58E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 D521_1886 f622d83b28426446be8154dfea664c57 152 PRINTS PR01404 DATP pyrophosphohydrolase signature 1 17 2.2E-16 T 14-10-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 D521_1886 f622d83b28426446be8154dfea664c57 152 PRINTS PR01404 DATP pyrophosphohydrolase signature 70 89 2.2E-16 T 14-10-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 D521_1886 f622d83b28426446be8154dfea664c57 152 PRINTS PR01404 DATP pyrophosphohydrolase signature 127 140 2.2E-16 T 14-10-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 D521_1886 f622d83b28426446be8154dfea664c57 152 PRINTS PR01404 DATP pyrophosphohydrolase signature 17 38 2.2E-16 T 14-10-2018 IPR003564 Dihydroneopterin triphosphate diphosphatase GO:0008828|GO:0019177|GO:0046656 KEGG: 00790+3.6.1.67|MetaCyc: PWY-6147 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 379 445 1.0E-11 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 102 111 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 SUPERFAMILY SSF55957 363 447 9.81E-18 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 Gene3D G3DSA:3.40.120.10 5 159 6.0E-46 T 14-10-2018 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 SUPERFAMILY SSF53738 162 262 6.28E-29 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 240 255 2.0E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 180 199 2.0E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 101 115 2.0E-13 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 5 450 45.429 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 SUPERFAMILY SSF53738 264 371 3.88E-29 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 Gene3D G3DSA:3.40.120.10 263 345 6.1E-62 T 14-10-2018 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 9 447 4.2E-176 T 14-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 264 371 6.3E-32 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 SUPERFAMILY SSF53738 3 187 3.18E-47 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 Gene3D G3DSA:3.40.120.10 180 368 6.1E-62 T 14-10-2018 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 Gene3D G3DSA:3.30.310.50 376 450 9.1E-22 T 14-10-2018 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 163 260 1.8E-18 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0786 d7d8c498cbebc8f77fcaff66084ec005 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 6 141 7.6E-43 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 TIGRFAM TIGR00165 S18: ribosomal protein bS18 19 86 1.7E-33 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 SUPERFAMILY SSF46911 14 88 4.45E-26 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 35 87 8.0E-21 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 16 87 19.896 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 ProSitePatterns PS00057 Ribosomal protein S18 signature. 35 58 - T 14-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 PRINTS PR00974 Ribosomal protein S18 family signature 52 59 1.0E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 PRINTS PR00974 Ribosomal protein S18 family signature 60 74 1.0E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 PRINTS PR00974 Ribosomal protein S18 family signature 74 84 1.0E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 PRINTS PR00974 Ribosomal protein S18 family signature 42 52 1.0E-15 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 Pfam PF01084 Ribosomal protein S18 33 82 2.3E-22 T 14-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1400 d8d6dd441002d975c7341e6345ae65c3 90 Gene3D G3DSA:4.10.640.10 4 90 3.5E-25 T 14-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0750 a5732cfdacc787b5c00f4ab132740e20 168 PIRSF PIRSF000216 2 168 2.1E-52 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0750 a5732cfdacc787b5c00f4ab132740e20 168 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 17 161 3.6E-46 T 14-10-2018 D521_0750 a5732cfdacc787b5c00f4ab132740e20 168 Gene3D G3DSA:3.40.30.10 79 168 1.2E-20 T 14-10-2018 D521_0750 a5732cfdacc787b5c00f4ab132740e20 168 Gene3D G3DSA:1.10.10.1590 5 78 3.5E-24 T 14-10-2018 D521_0750 a5732cfdacc787b5c00f4ab132740e20 168 SUPERFAMILY SSF52833 8 163 1.45E-47 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0750 a5732cfdacc787b5c00f4ab132740e20 168 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 15 161 2.7E-56 T 14-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0572 3d5dd2d126e1d70759047c7c11ea6f8a 536 Gene3D G3DSA:3.30.70.2700 1 80 2.9E-25 T 14-10-2018 D521_0572 3d5dd2d126e1d70759047c7c11ea6f8a 536 Gene3D G3DSA:3.50.50.60 467 535 1.4E-14 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0572 3d5dd2d126e1d70759047c7c11ea6f8a 536 Gene3D G3DSA:3.50.50.60 85 301 1.1E-81 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0572 3d5dd2d126e1d70759047c7c11ea6f8a 536 SUPERFAMILY SSF51905 103 530 2.33E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0572 3d5dd2d126e1d70759047c7c11ea6f8a 536 PIRSF PIRSF038984 1 536 8.3E-239 T 14-10-2018 IPR028348 FAD dependent protein D521_0572 3d5dd2d126e1d70759047c7c11ea6f8a 536 Pfam PF03486 HI0933-like protein 103 267 2.3E-6 T 14-10-2018 D521_1867 e67f2c5f2c5e5bbf74e5932a9cb6294f 456 SMART SM01011 2 143 2.1E-49 T 14-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 D521_1867 e67f2c5f2c5e5bbf74e5932a9cb6294f 456 Pfam PF00557 Metallopeptidase family M24 188 431 4.1E-60 T 14-10-2018 IPR000994 Peptidase M24 D521_1867 e67f2c5f2c5e5bbf74e5932a9cb6294f 456 Pfam PF05195 Aminopeptidase P, N-terminal domain 7 133 4.0E-32 T 14-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 D521_1867 e67f2c5f2c5e5bbf74e5932a9cb6294f 456 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 359 371 - T 14-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site D521_1867 e67f2c5f2c5e5bbf74e5932a9cb6294f 456 SUPERFAMILY SSF55920 182 455 5.63E-81 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like D521_1867 e67f2c5f2c5e5bbf74e5932a9cb6294f 456 Gene3D G3DSA:3.90.230.10 180 456 1.9E-91 T 14-10-2018 D521_1867 e67f2c5f2c5e5bbf74e5932a9cb6294f 456 SUPERFAMILY SSF53092 4 181 3.66E-47 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal D521_1867 e67f2c5f2c5e5bbf74e5932a9cb6294f 456 Gene3D G3DSA:3.40.350.10 4 178 3.5E-49 T 14-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal D521_1012 13ce48b36e389e8817bc61715ad8bc72 139 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 10 133 9.2E-38 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1012 13ce48b36e389e8817bc61715ad8bc72 139 Gene3D G3DSA:1.20.1300.10 4 136 1.0E-37 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1012 13ce48b36e389e8817bc61715ad8bc72 139 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 11 130 2.7E-25 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1012 13ce48b36e389e8817bc61715ad8bc72 139 PIRSF PIRSF000178 1 136 6.6E-29 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1012 13ce48b36e389e8817bc61715ad8bc72 139 SUPERFAMILY SSF81343 6 135 2.45E-29 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_0075 3cee506101e4c7b4f03709a20ba9dea6 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 26.658 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0075 3cee506101e4c7b4f03709a20ba9dea6 121 PIRSF PIRSF002134 1 121 1.1E-39 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0075 3cee506101e4c7b4f03709a20ba9dea6 121 Pfam PF00416 Ribosomal protein S13/S18 63 108 3.3E-18 T 14-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0075 3cee506101e4c7b4f03709a20ba9dea6 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 14-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0075 3cee506101e4c7b4f03709a20ba9dea6 121 Gene3D G3DSA:1.10.8.50 1 71 2.6E-25 T 14-10-2018 D521_0075 3cee506101e4c7b4f03709a20ba9dea6 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 3.5E-52 T 14-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0075 3cee506101e4c7b4f03709a20ba9dea6 121 Gene3D G3DSA:4.10.910.10 72 116 9.7E-26 T 14-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0075 3cee506101e4c7b4f03709a20ba9dea6 121 SUPERFAMILY SSF46946 2 114 8.71E-45 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 D521_0700 579aedce604e4866b96c42ed46cb342c 375 Pfam PF02445 Quinolinate synthetase A protein 46 352 5.9E-101 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 D521_0700 579aedce604e4866b96c42ed46cb342c 375 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 45 354 6.2E-104 T 14-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 D521_0700 579aedce604e4866b96c42ed46cb342c 375 Gene3D G3DSA:3.40.50.10800 46 334 2.9E-94 T 14-10-2018 D521_0700 579aedce604e4866b96c42ed46cb342c 375 SUPERFAMILY SSF142754 43 353 4.45E-106 T 14-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 D521_0700 579aedce604e4866b96c42ed46cb342c 375 Gene3D G3DSA:3.40.50.10800 214 309 2.9E-94 T 14-10-2018 D521_0700 579aedce604e4866b96c42ed46cb342c 375 Gene3D G3DSA:3.40.50.10800 129 352 2.9E-94 T 14-10-2018 D521_1161 aeb56511326ec7eb1b790b5a73d69eeb 55 Gene3D G3DSA:2.20.28.10 1 55 1.3E-28 T 14-10-2018 D521_1161 aeb56511326ec7eb1b790b5a73d69eeb 55 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 D521_1161 aeb56511326ec7eb1b790b5a73d69eeb 55 Pfam PF00301 Rubredoxin 4 49 4.4E-23 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 D521_1161 aeb56511326ec7eb1b790b5a73d69eeb 55 PIRSF PIRSF000071 1 55 1.9E-26 T 14-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 D521_1161 aeb56511326ec7eb1b790b5a73d69eeb 55 SUPERFAMILY SSF57802 1 53 1.85E-22 T 14-10-2018 D521_1161 aeb56511326ec7eb1b790b5a73d69eeb 55 PRINTS PR00163 Rubredoxin signature 3 19 3.0E-9 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 D521_1161 aeb56511326ec7eb1b790b5a73d69eeb 55 PRINTS PR00163 Rubredoxin signature 33 49 3.0E-9 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 D521_1920 38dc120af4b13846d2d28d32f558146e 89 Pfam PF00037 4Fe-4S binding domain 6 25 4.5E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1920 38dc120af4b13846d2d28d32f558146e 89 SUPERFAMILY SSF54862 4 70 1.6E-18 T 14-10-2018 D521_1920 38dc120af4b13846d2d28d32f558146e 89 Gene3D G3DSA:3.30.70.20 2 81 1.7E-31 T 14-10-2018 D521_1920 38dc120af4b13846d2d28d32f558146e 89 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 Pfam PF07724 AAA domain (Cdc48 subfamily) 489 650 4.1E-48 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 SUPERFAMILY SSF81923 1 143 2.35E-56 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 Gene3D G3DSA:3.40.50.300 443 654 1.4E-79 T 14-10-2018 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 Gene3D G3DSA:1.10.8.60 656 754 2.9E-25 T 14-10-2018 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 Gene3D G3DSA:3.40.50.300 169 358 2.8E-66 T 14-10-2018 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 737 0.0 T 14-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 SUPERFAMILY SSF52540 171 424 8.72E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 Gene3D G3DSA:1.10.8.60 359 441 7.1E-34 T 14-10-2018 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 214 345 1.7E-12 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 521 539 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 494 512 1.1E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 598 612 1.1E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 565 583 1.1E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 536 554 1.1E-38 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 Gene3D G3DSA:1.10.1780.10 1 144 1.4E-38 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 SMART SM01086 656 746 1.7E-30 T 14-10-2018 IPR019489 Clp ATPase, C-terminal D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 305 317 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 656 736 3.4E-21 T 14-10-2018 IPR019489 Clp ATPase, C-terminal D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 SUPERFAMILY SSF52540 440 741 8.56E-75 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 62 1.8E-11 T 14-10-2018 IPR004176 Clp, N-terminal D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 SMART SM00382 209 355 4.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1730 7cd2e3ff841fa2c7fd6a87c34c141982 768 SMART SM00382 490 639 2.2E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0722 5618577ee1289c7d3d437d7170d8d305 166 SUPERFAMILY SSF54534 87 165 9.94E-19 T 14-10-2018 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 Gene3D G3DSA:3.10.50.30 82 166 5.0E-24 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 TIGRFAM TIGR01461 greB: transcription elongation factor GreB 4 165 4.9E-59 T 14-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 129 145 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 Gene3D G3DSA:1.10.287.180 2 77 1.1E-24 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 88 165 3.2E-23 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 SUPERFAMILY SSF46557 4 78 2.62E-24 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 Hamap MF_00105 Transcription elongation factor GreA [greA]. 3 164 23.813 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 Hamap MF_00930 Transcription elongation factor GreB [greB]. 2 166 51.269 T 14-10-2018 IPR006358 Transcription elongation factor GreB GO:0003677|GO:0032784 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 Pfam PF03449 Transcription elongation factor, N-terminal 5 75 8.9E-22 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 PIRSF PIRSF006092 1 166 3.8E-42 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 D521_0722 5618577ee1289c7d3d437d7170d8d305 166 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 18 49 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 D521_0365 090ae862c46ba002a66affe75c289e10 337 SMART SM00477 47 236 9.2E-25 T 14-10-2018 IPR020821 Extracellular Endonuclease, subunit A GO:0003676|GO:0016787|GO:0046872 D521_0365 090ae862c46ba002a66affe75c289e10 337 Pfam PF01223 DNA/RNA non-specific endonuclease 38 230 4.1E-37 T 14-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 D521_0365 090ae862c46ba002a66affe75c289e10 337 SUPERFAMILY SSF54060 25 229 3.53E-52 T 14-10-2018 D521_0365 090ae862c46ba002a66affe75c289e10 337 Gene3D G3DSA:3.40.570.10 33 243 2.7E-43 T 14-10-2018 D521_0365 090ae862c46ba002a66affe75c289e10 337 SMART SM00892 46 235 2.7E-26 T 14-10-2018 IPR001604 DNA/RNA non-specific endonuclease GO:0003676|GO:0016787|GO:0046872 D521_1916 b4b1fddf336d55a1cbbc578f51dca286 291 Pfam PF00288 GHMP kinases N terminal domain 89 145 1.7E-10 T 14-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 D521_1916 b4b1fddf336d55a1cbbc578f51dca286 291 Gene3D G3DSA:3.30.230.10 1 161 4.1E-57 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup D521_1916 b4b1fddf336d55a1cbbc578f51dca286 291 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 7 258 9.2E-73 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 D521_1916 b4b1fddf336d55a1cbbc578f51dca286 291 PIRSF PIRSF010376 4 286 7.3E-86 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 D521_1916 b4b1fddf336d55a1cbbc578f51dca286 291 SUPERFAMILY SSF55060 162 283 2.78E-21 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily D521_1916 b4b1fddf336d55a1cbbc578f51dca286 291 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 6 278 31.306 T 14-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 D521_1916 b4b1fddf336d55a1cbbc578f51dca286 291 Gene3D G3DSA:3.30.70.890 163 289 5.4E-24 T 14-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily D521_1916 b4b1fddf336d55a1cbbc578f51dca286 291 SUPERFAMILY SSF54211 8 157 1.06E-45 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_1907 70ba54bf28d51a23cc00330a59af5a47 255 SUPERFAMILY SSF52540 14 251 2.33E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1907 70ba54bf28d51a23cc00330a59af5a47 255 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_1907 70ba54bf28d51a23cc00330a59af5a47 255 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 13 255 2.1E-117 T 14-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 D521_1907 70ba54bf28d51a23cc00330a59af5a47 255 Gene3D G3DSA:3.40.50.300 12 255 1.0E-71 T 14-10-2018 D521_1907 70ba54bf28d51a23cc00330a59af5a47 255 SMART SM00382 38 245 3.0E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1907 70ba54bf28d51a23cc00330a59af5a47 255 Pfam PF00005 ABC transporter 30 180 8.5E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_1907 70ba54bf28d51a23cc00330a59af5a47 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 250 7.0E-7 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal D521_0133 8821a067dff9b74fc2b1b86e4f72c2ff 282 SUPERFAMILY SSF53335 17 266 8.29E-52 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0133 8821a067dff9b74fc2b1b86e4f72c2ff 282 Gene3D G3DSA:1.10.8.10 2 85 1.5E-15 T 14-10-2018 D521_0133 8821a067dff9b74fc2b1b86e4f72c2ff 282 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 280 39.693 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 D521_0133 8821a067dff9b74fc2b1b86e4f72c2ff 282 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 23 280 2.4E-71 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 D521_0133 8821a067dff9b74fc2b1b86e4f72c2ff 282 Gene3D G3DSA:3.40.50.150 86 281 2.0E-56 T 14-10-2018 D521_0133 8821a067dff9b74fc2b1b86e4f72c2ff 282 Pfam PF05175 Methyltransferase small domain 111 196 7.0E-15 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 D521_0133 8821a067dff9b74fc2b1b86e4f72c2ff 282 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 21 275 1.1E-81 T 14-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 D521_0133 8821a067dff9b74fc2b1b86e4f72c2ff 282 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 185 191 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 D521_0185 3bbd69dc9cc65d6987b763d063900c9f 97 Pfam PF01478 Type IV leader peptidase family 12 53 6.1E-10 T 14-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 D521_0185 3bbd69dc9cc65d6987b763d063900c9f 97 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 11 21 4.3E-13 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial D521_0185 3bbd69dc9cc65d6987b763d063900c9f 97 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 22 33 4.3E-13 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial D521_0185 3bbd69dc9cc65d6987b763d063900c9f 97 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 34 49 4.3E-13 T 14-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial D521_0599 ac17e07ef78b13fdea54d0b494f34215 261 PIRSF PIRSF000094 1 260 1.9E-110 T 14-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 D521_0599 ac17e07ef78b13fdea54d0b494f34215 261 SUPERFAMILY SSF51735 6 252 3.93E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0599 ac17e07ef78b13fdea54d0b494f34215 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 252 4.1E-80 T 14-10-2018 D521_0599 ac17e07ef78b13fdea54d0b494f34215 261 Gene3D G3DSA:3.40.50.720 1 258 1.8E-49 T 14-10-2018 D521_0288 150c9298c02880b49db282383e462754 363 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 30 344 3.8E-58 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 D521_0288 150c9298c02880b49db282383e462754 363 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 24 353 2.8E-89 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 D521_0288 150c9298c02880b49db282383e462754 363 SUPERFAMILY SSF52540 57 166 4.2E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0288 150c9298c02880b49db282383e462754 363 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 12 357 32.705 T 14-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 D521_1118 6e130d5cc9af6b280f61dc14c06173d5 190 SUPERFAMILY SSF158442 18 129 7.98E-19 T 14-10-2018 IPR023380 DsbB-like superfamily D521_1118 6e130d5cc9af6b280f61dc14c06173d5 190 Pfam PF02600 Disulfide bond formation protein DsbB 19 99 2.9E-11 T 14-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 D521_1118 6e130d5cc9af6b280f61dc14c06173d5 190 Gene3D G3DSA:1.20.1550.10 13 166 6.0E-8 T 14-10-2018 IPR023380 DsbB-like superfamily D521_1525 d8cbc4e5b2f34aa329c480534d958e1f 307 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 41 301 2.0E-89 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III D521_1525 d8cbc4e5b2f34aa329c480534d958e1f 307 Gene3D G3DSA:1.10.760.10 189 275 1.9E-74 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1525 d8cbc4e5b2f34aa329c480534d958e1f 307 PIRSF PIRSF000006 5 302 2.8E-102 T 14-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III D521_1525 d8cbc4e5b2f34aa329c480534d958e1f 307 Gene3D G3DSA:1.20.58.1490 4 101 2.5E-30 T 14-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily D521_1525 d8cbc4e5b2f34aa329c480534d958e1f 307 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 45 90 3.1E-23 T 14-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal D521_1525 d8cbc4e5b2f34aa329c480534d958e1f 307 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 219 295 9.3E-14 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1525 d8cbc4e5b2f34aa329c480534d958e1f 307 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 137 207 4.3E-12 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1525 d8cbc4e5b2f34aa329c480534d958e1f 307 SUPERFAMILY SSF46626 214 304 4.15E-26 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1525 d8cbc4e5b2f34aa329c480534d958e1f 307 SUPERFAMILY SSF46626 63 217 5.3E-33 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1525 d8cbc4e5b2f34aa329c480534d958e1f 307 Gene3D G3DSA:1.10.760.10 111 298 1.9E-74 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Pfam PF03483 B3/4 domain 219 399 1.5E-63 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Gene3D G3DSA:3.50.40.10 203 408 2.1E-71 T 14-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Pfam PF03147 Ferredoxin-fold anticodon binding domain 722 819 4.1E-26 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 SUPERFAMILY SSF56037 204 405 5.75E-66 T 14-10-2018 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Pfam PF01588 Putative tRNA binding domain 45 151 6.8E-25 T 14-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Gene3D G3DSA:3.30.56.10 413 488 2.0E-23 T 14-10-2018 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Pfam PF03484 tRNA synthetase B5 domain 418 484 4.1E-20 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Gene3D G3DSA:3.30.70.380 723 819 2.2E-23 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Gene3D G3DSA:3.30.930.10 503 710 3.6E-52 T 14-10-2018 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 813 42.592 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Gene3D G3DSA:3.30.56.10 4 188 1.6E-69 T 14-10-2018 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 SUPERFAMILY SSF54991 718 819 1.96E-21 T 14-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 Gene3D G3DSA:2.40.50.140 39 160 1.6E-69 T 14-10-2018 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 SUPERFAMILY SSF55681 480 712 2.29E-44 T 14-10-2018 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 SUPERFAMILY SSF50249 38 204 8.08E-49 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_0840 cf766281c7847c5ec24ca386ced1a224 819 SMART SM00896 722 819 2.7E-35 T 14-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 819 2.5E-230 T 14-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 SMART SM00874 415 484 1.9E-27 T 14-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 SMART SM00873 218 399 3.0E-80 T 14-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 D521_0840 cf766281c7847c5ec24ca386ced1a224 819 SUPERFAMILY SSF46955 415 488 3.02E-18 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Pfam PF04545 Sigma-70, region 4 634 687 1.1E-18 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 SUPERFAMILY SSF88659 539 612 2.18E-17 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Pfam PF00140 Sigma-70 factor, region 1.2 180 212 1.2E-12 T 14-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 SUPERFAMILY SSF88946 197 533 5.81E-93 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 PRINTS PR00046 Major sigma-70 factor signature 659 674 1.3E-30 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 PRINTS PR00046 Major sigma-70 factor signature 514 522 1.3E-30 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 PRINTS PR00046 Major sigma-70 factor signature 490 503 1.3E-30 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 PRINTS PR00046 Major sigma-70 factor signature 674 685 1.3E-30 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 PRINTS PR00046 Major sigma-70 factor signature 638 650 1.3E-30 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Gene3D G3DSA:1.10.10.10 616 700 1.0E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 490 503 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Gene3D G3DSA:1.10.10.10 539 614 2.6E-29 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Pfam PF03979 Sigma-70 factor, region 1.1 84 163 1.7E-21 T 14-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Pfam PF04546 Sigma-70, non-essential region 221 435 1.2E-54 T 14-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Pfam PF04542 Sigma-70 region 2 469 535 2.4E-20 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 SUPERFAMILY SSF88659 596 698 6.35E-27 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Gene3D G3DSA:1.10.220.120 81 144 8.3E-19 T 14-10-2018 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Pfam PF04539 Sigma-70 region 3 545 621 6.3E-24 T 14-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 462 698 4.0E-116 T 14-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 462 687 2.0E-38 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Gene3D G3DSA:1.10.601.10 195 535 4.4E-120 T 14-10-2018 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 62 699 39.929 T 14-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 D521_1686 1e71780be31bdb7bbed37efe24e25d4b 701 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 659 685 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1597 832873b55c1a1f041efae82427f0b88e 413 Pfam PF00665 Integrase core domain 234 339 4.6E-13 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 D521_1597 832873b55c1a1f041efae82427f0b88e 413 ProSitePatterns PS01043 Transposases, IS30 family, signature. 326 342 - T 14-10-2018 IPR001598 Transposase, IS30, conserved site GO:0003677|GO:0004803|GO:0006313 D521_1597 832873b55c1a1f041efae82427f0b88e 413 Gene3D G3DSA:3.30.420.10 236 411 6.5E-7 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_1597 832873b55c1a1f041efae82427f0b88e 413 Pfam PF13565 Homeodomain-like domain 109 174 1.4E-8 T 14-10-2018 D521_1597 832873b55c1a1f041efae82427f0b88e 413 Pfam PF13936 Helix-turn-helix domain 62 102 9.2E-16 T 14-10-2018 IPR025246 Transposase IS30-like HTH domain D521_1597 832873b55c1a1f041efae82427f0b88e 413 SUPERFAMILY SSF53098 234 378 3.34E-27 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1632 7a3f20b6f6ad51e3a2056d8d25972308 255 Pfam PF00072 Response regulator receiver domain 32 141 8.8E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1632 7a3f20b6f6ad51e3a2056d8d25972308 255 SUPERFAMILY SSF46894 157 248 7.65E-11 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 D521_1632 7a3f20b6f6ad51e3a2056d8d25972308 255 Pfam PF00486 Transcriptional regulatory protein, C terminal 174 247 7.6E-8 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 D521_1632 7a3f20b6f6ad51e3a2056d8d25972308 255 SMART SM00448 30 141 1.0E-31 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1632 7a3f20b6f6ad51e3a2056d8d25972308 255 Gene3D G3DSA:3.40.50.2300 28 154 6.6E-28 T 14-10-2018 D521_1632 7a3f20b6f6ad51e3a2056d8d25972308 255 Gene3D G3DSA:1.10.10.10 155 252 5.1E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1632 7a3f20b6f6ad51e3a2056d8d25972308 255 SUPERFAMILY SSF52172 27 149 4.27E-31 T 14-10-2018 IPR011006 CheY-like superfamily D521_0002 b4608d238dd6a60b7183eee4df45803a 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 131 248 3.1E-32 T 14-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 D521_0002 b4608d238dd6a60b7183eee4df45803a 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 7 119 8.4E-28 T 14-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 D521_0002 b4608d238dd6a60b7183eee4df45803a 371 SUPERFAMILY SSF55979 130 249 3.56E-27 T 14-10-2018 D521_0002 b4608d238dd6a60b7183eee4df45803a 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 251 370 4.5E-36 T 14-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 D521_0002 b4608d238dd6a60b7183eee4df45803a 371 SMART SM00480 18 367 2.8E-119 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 D521_0002 b4608d238dd6a60b7183eee4df45803a 371 Gene3D G3DSA:3.70.10.10 139 369 5.3E-115 T 14-10-2018 D521_0002 b4608d238dd6a60b7183eee4df45803a 371 PIRSF PIRSF000804 1 371 1.1E-111 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 D521_0002 b4608d238dd6a60b7183eee4df45803a 371 SUPERFAMILY SSF55979 6 117 4.49E-22 T 14-10-2018 D521_0002 b4608d238dd6a60b7183eee4df45803a 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 5 370 2.2E-98 T 14-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 D521_0002 b4608d238dd6a60b7183eee4df45803a 371 SUPERFAMILY SSF55979 250 371 1.88E-38 T 14-10-2018 D521_0002 b4608d238dd6a60b7183eee4df45803a 371 Gene3D G3DSA:3.10.150.10 6 247 5.3E-115 T 14-10-2018 D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 Gene3D G3DSA:3.60.20.40 346 532 5.0E-65 T 14-10-2018 D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 SUPERFAMILY SSF56235 5 531 7.33E-146 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 Pfam PF01019 Gamma-glutamyltranspeptidase 24 527 5.0E-126 T 14-10-2018 D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 224 240 2.6E-23 T 14-10-2018 D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 401 416 2.6E-23 T 14-10-2018 D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 126 145 2.6E-23 T 14-10-2018 D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 346 364 2.6E-23 T 14-10-2018 D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 31 56 2.6E-23 T 14-10-2018 D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 370 388 2.6E-23 T 14-10-2018 D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 253 272 2.6E-23 T 14-10-2018 D521_1842 62106dde2b1c8e9f932bfc008afbbe1b 532 Gene3D G3DSA:1.10.246.130 240 345 8.1E-21 T 14-10-2018 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 Gene3D G3DSA:3.20.20.70 2 277 8.1E-106 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 Gene3D G3DSA:1.10.238.260 281 395 2.6E-35 T 14-10-2018 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 SMART SM00917 371 502 2.5E-41 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 511 41.837 T 14-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 SUPERFAMILY SSF110921 395 501 1.7E-26 T 14-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 4 499 1.1E-206 T 14-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 Gene3D G3DSA:3.30.160.270 396 502 6.4E-14 T 14-10-2018 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 Pfam PF00682 HMGL-like 4 274 5.4E-94 T 14-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 Pfam PF08502 LeuA allosteric (dimerisation) domain 371 501 4.8E-36 T 14-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 SUPERFAMILY SSF51569 1 292 3.85E-96 T 14-10-2018 D521_0738 8c67cd091be7a5c6f4fa1dcb9366ecbe 515 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 14-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 D521_1741 c0c66d97f1b13b20759162be738b9452 219 Pfam PF09335 SNARE associated Golgi protein 54 178 1.6E-22 T 14-10-2018 IPR032816 SNARE associated Golgi protein D521_1483 0b0e25314f2bdd63af1d6539214bb749 365 SUPERFAMILY SSF53383 6 363 2.31E-115 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_1483 0b0e25314f2bdd63af1d6539214bb749 365 Pfam PF00266 Aminotransferase class-V 7 354 1.7E-55 T 14-10-2018 IPR000192 Aminotransferase class V domain D521_1483 0b0e25314f2bdd63af1d6539214bb749 365 Gene3D G3DSA:3.90.1150.10 257 365 3.5E-42 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_1483 0b0e25314f2bdd63af1d6539214bb749 365 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 7 364 6.7E-152 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 D521_1483 0b0e25314f2bdd63af1d6539214bb749 365 PIRSF PIRSF000525 1 365 1.6E-148 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 D521_1483 0b0e25314f2bdd63af1d6539214bb749 365 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 5 365 48.563 T 14-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 D521_1483 0b0e25314f2bdd63af1d6539214bb749 365 Gene3D G3DSA:3.40.640.10 20 256 8.0E-90 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0089 8905ead38c799cd972b03190e55b98e1 370 Gene3D G3DSA:3.55.50.30 25 127 3.0E-22 T 14-10-2018 D521_0089 8905ead38c799cd972b03190e55b98e1 370 PRINTS PR00811 Bacterial general secretion pathway protein D signature 332 350 1.0E-24 T 14-10-2018 IPR001775 GspD/PilQ family D521_0089 8905ead38c799cd972b03190e55b98e1 370 PRINTS PR00811 Bacterial general secretion pathway protein D signature 139 149 1.0E-24 T 14-10-2018 IPR001775 GspD/PilQ family D521_0089 8905ead38c799cd972b03190e55b98e1 370 PRINTS PR00811 Bacterial general secretion pathway protein D signature 245 255 1.0E-24 T 14-10-2018 IPR001775 GspD/PilQ family D521_0089 8905ead38c799cd972b03190e55b98e1 370 PRINTS PR00811 Bacterial general secretion pathway protein D signature 355 369 1.0E-24 T 14-10-2018 IPR001775 GspD/PilQ family D521_0089 8905ead38c799cd972b03190e55b98e1 370 PRINTS PR00811 Bacterial general secretion pathway protein D signature 210 234 1.0E-24 T 14-10-2018 IPR001775 GspD/PilQ family D521_0089 8905ead38c799cd972b03190e55b98e1 370 Pfam PF00263 Bacterial type II and III secretion system protein 214 367 2.6E-45 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 D521_0089 8905ead38c799cd972b03190e55b98e1 370 ProSitePatterns PS00875 Bacterial type II secretion system protein D signature. 313 346 - T 14-10-2018 IPR004845 Type II secretion system GspD, conserved site GO:0008565 D521_0089 8905ead38c799cd972b03190e55b98e1 370 Pfam PF07660 Secretin and TonB N terminus short domain 64 110 3.2E-7 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 D521_0089 8905ead38c799cd972b03190e55b98e1 370 SMART SM00965 63 111 2.0E-4 T 14-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 SUPERFAMILY SSF54980 400 515 1.77E-28 T 14-10-2018 IPR035647 EF-G domain III/V-like D521_0614 9ed18b1bb0d8458e878412bad538e911 605 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 6 601 9.8E-286 T 14-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 Gene3D G3DSA:2.40.50.250 485 601 1.2E-130 T 14-10-2018 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 Gene3D G3DSA:2.40.30.10 201 301 5.8E-30 T 14-10-2018 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 Gene3D G3DSA:3.30.70.870 308 592 1.2E-130 T 14-10-2018 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 SUPERFAMILY SSF54980 304 389 2.63E-13 T 14-10-2018 IPR035647 EF-G domain III/V-like D521_0614 9ed18b1bb0d8458e878412bad538e911 605 Gene3D G3DSA:3.40.50.300 4 198 1.1E-64 T 14-10-2018 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 Pfam PF00679 Elongation factor G C-terminus 398 479 4.8E-24 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like D521_0614 9ed18b1bb0d8458e878412bad538e911 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 139 5.4E-24 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 SMART SM00838 397 485 7.3E-4 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like D521_0614 9ed18b1bb0d8458e878412bad538e911 605 SUPERFAMILY SSF50447 152 301 4.29E-31 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily D521_0614 9ed18b1bb0d8458e878412bad538e911 605 Pfam PF00009 Elongation factor Tu GTP binding domain 6 196 9.8E-55 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 SUPERFAMILY SSF52540 4 207 7.4E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0614 9ed18b1bb0d8458e878412bad538e911 605 PRINTS PR00315 GTP-binding elongation factor signature 52 60 5.7E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 PRINTS PR00315 GTP-binding elongation factor signature 88 99 5.7E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 PRINTS PR00315 GTP-binding elongation factor signature 72 82 5.7E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 PRINTS PR00315 GTP-binding elongation factor signature 8 21 5.7E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 PRINTS PR00315 GTP-binding elongation factor signature 124 133 5.7E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site D521_0614 9ed18b1bb0d8458e878412bad538e911 605 Pfam PF03144 Elongation factor Tu domain 2 220 291 1.1E-10 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 D521_0614 9ed18b1bb0d8458e878412bad538e911 605 Gene3D G3DSA:3.30.70.240 391 484 1.2E-130 T 14-10-2018 D521_1368 a681965660698150b6ea6f5df813c300 469 SMART SM00465 205 286 2.5E-11 T 14-10-2018 IPR000305 GIY-YIG endonuclease D521_1368 a681965660698150b6ea6f5df813c300 469 SUPERFAMILY SSF53098 10 207 7.6E-45 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1368 a681965660698150b6ea6f5df813c300 469 Gene3D G3DSA:3.40.1440.10 193 290 5.3E-23 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 D521_1368 a681965660698150b6ea6f5df813c300 469 Pfam PF00929 Exonuclease 13 160 1.4E-25 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III D521_1368 a681965660698150b6ea6f5df813c300 469 SMART SM00479 10 174 2.1E-33 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III D521_1368 a681965660698150b6ea6f5df813c300 469 Gene3D G3DSA:3.30.420.10 7 172 1.6E-40 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_1368 a681965660698150b6ea6f5df813c300 469 SUPERFAMILY SSF82771 205 286 1.7E-13 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 D521_1368 a681965660698150b6ea6f5df813c300 469 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 14 170 5.8E-22 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_0117 6b95f4c271574f8f006e0501d36f2424 265 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 9 247 16.693 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 D521_0117 6b95f4c271574f8f006e0501d36f2424 265 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 162 190 1.6E-45 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 D521_0117 6b95f4c271574f8f006e0501d36f2424 265 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 15 42 1.6E-45 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 D521_0117 6b95f4c271574f8f006e0501d36f2424 265 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 110 136 1.6E-45 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 D521_0117 6b95f4c271574f8f006e0501d36f2424 265 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 92 110 1.6E-45 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 D521_0117 6b95f4c271574f8f006e0501d36f2424 265 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 17 234 1.3E-68 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 D521_0117 6b95f4c271574f8f006e0501d36f2424 265 Pfam PF00902 Sec-independent protein translocase protein (TatC) 19 229 1.2E-66 T 14-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 D521_0226 858993148bf0868f09d04a697888e840 340 Pfam PF02769 AIR synthase related protein, C-terminal domain 162 309 4.1E-8 T 14-10-2018 IPR010918 PurM-like, C-terminal domain D521_0226 858993148bf0868f09d04a697888e840 340 PIRSF PIRSF005303 3 327 1.7E-77 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 D521_0226 858993148bf0868f09d04a697888e840 340 SUPERFAMILY SSF55326 6 148 5.08E-34 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily D521_0226 858993148bf0868f09d04a697888e840 340 SUPERFAMILY SSF56042 152 306 4.93E-35 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily D521_0226 858993148bf0868f09d04a697888e840 340 Pfam PF00586 AIR synthase related protein, N-terminal domain 39 147 7.1E-26 T 14-10-2018 IPR016188 PurM-like, N-terminal domain D521_0226 858993148bf0868f09d04a697888e840 340 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 8 339 27.063 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 D521_0226 858993148bf0868f09d04a697888e840 340 Gene3D G3DSA:3.90.650.10 156 340 5.7E-46 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily D521_0226 858993148bf0868f09d04a697888e840 340 Gene3D G3DSA:3.30.1330.10 7 154 6.2E-47 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily D521_0226 858993148bf0868f09d04a697888e840 340 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 9 309 1.8E-91 T 14-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 D521_0692 4763c14aa7dc8fa759d6ae2d0fee8bfe 801 Pfam PF05359 Domain of Unknown Function (DUF748) 410 555 2.6E-27 T 14-10-2018 IPR008023 Protein of unknown function DUF748 D521_0276 0c501e97a145db5725ace9a25c8ae234 166 Pfam PF00691 OmpA family 62 157 2.1E-20 T 14-10-2018 IPR006665 OmpA-like domain D521_0276 0c501e97a145db5725ace9a25c8ae234 166 Gene3D G3DSA:3.30.1330.60 46 164 1.1E-37 T 14-10-2018 IPR036737 OmpA-like domain superfamily D521_0276 0c501e97a145db5725ace9a25c8ae234 166 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 60 163 8.1E-43 T 14-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 D521_0276 0c501e97a145db5725ace9a25c8ae234 166 SUPERFAMILY SSF103088 56 163 2.49E-31 T 14-10-2018 IPR036737 OmpA-like domain superfamily D521_0276 0c501e97a145db5725ace9a25c8ae234 166 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 7 163 29.26 T 14-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 D521_0276 0c501e97a145db5725ace9a25c8ae234 166 PRINTS PR01021 OMPA domain signature 93 108 1.8E-12 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 D521_0276 0c501e97a145db5725ace9a25c8ae234 166 PRINTS PR01021 OMPA domain signature 63 85 1.8E-12 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 D521_0276 0c501e97a145db5725ace9a25c8ae234 166 PRINTS PR01021 OMPA domain signature 108 124 1.8E-12 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 SUPERFAMILY SSF55785 6 127 6.28E-15 T 14-10-2018 IPR035965 PAS domain superfamily D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 136 1.6E-7 T 14-10-2018 IPR000014 PAS domain D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 Gene3D G3DSA:1.10.3210.10 314 499 2.0E-65 T 14-10-2018 D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 Gene3D G3DSA:3.30.450.20 5 138 1.2E-15 T 14-10-2018 D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 SUPERFAMILY SSF109604 322 495 6.0E-37 T 14-10-2018 D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 Pfam PF13487 HD domain 386 447 2.1E-20 T 14-10-2018 D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 Gene3D G3DSA:3.30.450.40 139 313 1.3E-22 T 14-10-2018 IPR029016 GAF-like domain superfamily D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 TIGRFAM TIGR00277 HDIG: HDIG domain 334 424 3.7E-9 T 14-10-2018 IPR006675 HDIG domain D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 SMART SM00471 330 465 1.3E-5 T 14-10-2018 IPR003607 HD/PDEase domain D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 SUPERFAMILY SSF55781 127 300 2.7E-19 T 14-10-2018 D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 Pfam PF08448 PAS fold 20 127 2.5E-12 T 14-10-2018 IPR013656 PAS fold-4 D521_0632 292d1863f8bce117552f5c5e5e7c9168 502 Pfam PF13185 GAF domain 157 301 2.8E-20 T 14-10-2018 IPR003018 GAF domain GO:0005515 D521_1910 f31546df68446fc15996a190d1a498bc 329 SUPERFAMILY SSF75138 9 142 1.1E-26 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily D521_1910 f31546df68446fc15996a190d1a498bc 329 Pfam PF02603 HPr Serine kinase N terminus 11 140 8.6E-25 T 14-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 D521_1910 f31546df68446fc15996a190d1a498bc 329 SUPERFAMILY SSF53795 146 311 3.97E-34 T 14-10-2018 D521_1910 f31546df68446fc15996a190d1a498bc 329 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 15 314 3.3E-97 T 14-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 D521_1910 f31546df68446fc15996a190d1a498bc 329 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 10 318 35.827 T 14-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 D521_1910 f31546df68446fc15996a190d1a498bc 329 Gene3D G3DSA:3.40.1390.20 17 142 2.3E-24 T 14-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily D521_1910 f31546df68446fc15996a190d1a498bc 329 Pfam PF07475 HPr Serine kinase C-terminal domain 145 311 4.3E-61 T 14-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 D521_1910 f31546df68446fc15996a190d1a498bc 329 Gene3D G3DSA:3.40.50.300 144 327 9.1E-62 T 14-10-2018 D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 SUPERFAMILY SSF55874 214 369 4.98E-31 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 252 370 2.8E-14 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 SMART SM00388 147 212 1.7E-15 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 SUPERFAMILY SSF47384 139 208 2.35E-14 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 Pfam PF08448 PAS fold 24 101 2.1E-5 T 14-10-2018 IPR013656 PAS fold-4 D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 SMART SM00091 18 86 3.3E-4 T 14-10-2018 IPR000014 PAS domain D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 SUPERFAMILY SSF55785 20 102 8.95E-8 T 14-10-2018 IPR035965 PAS domain superfamily D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 Gene3D G3DSA:3.30.565.10 210 371 4.0E-36 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 369 4.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 318 4.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 351 4.0E-9 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 Gene3D G3DSA:3.30.450.20 18 126 9.3E-10 T 14-10-2018 D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 Gene3D G3DSA:1.10.287.130 150 208 7.6E-14 T 14-10-2018 D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 SMART SM00387 252 372 5.7E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_1043 29e3b359ab3d04335cd680b93bd55be4 377 Pfam PF00512 His Kinase A (phospho-acceptor) domain 149 208 7.6E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_1250 266de2d2fff3cbd6c0873671e4c3f777 149 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 7 146 36.216 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 D521_1250 266de2d2fff3cbd6c0873671e4c3f777 149 Pfam PF07977 FabA-like domain 16 138 1.3E-35 T 14-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 D521_1250 266de2d2fff3cbd6c0873671e4c3f777 149 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 7 143 3.0E-60 T 14-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 D521_1250 266de2d2fff3cbd6c0873671e4c3f777 149 Gene3D G3DSA:3.10.129.10 1 147 1.4E-63 T 14-10-2018 D521_1250 266de2d2fff3cbd6c0873671e4c3f777 149 SUPERFAMILY SSF54637 9 147 1.24E-49 T 14-10-2018 IPR029069 HotDog domain superfamily D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 Gene3D G3DSA:3.90.700.10 259 369 6.1E-156 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 SUPERFAMILY SSF51905 7 457 9.98E-72 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 Gene3D G3DSA:3.50.50.60 19 415 6.1E-156 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 PIRSF PIRSF000171 10 538 3.7E-39 T 14-10-2018 D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 Pfam PF02910 Fumarate reductase flavoprotein C-term 450 529 1.9E-15 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 SUPERFAMILY SSF56425 249 364 3.14E-43 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 SUPERFAMILY SSF46977 435 531 6.41E-31 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 17 529 4.0E-188 T 14-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 Gene3D G3DSA:1.20.58.100 434 548 6.0E-42 T 14-10-2018 D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 Pfam PF00890 FAD binding domain 19 403 1.1E-100 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 19 38 1.0E-9 T 14-10-2018 D521_0697 dbd6ca9cd4f2b5f616df3fb6628e0bc1 553 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 366 388 1.0E-9 T 14-10-2018 D521_1860 3c470e6c8ccd4a14c250404ae5f12e4d 244 SMART SM00563 75 190 6.2E-28 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 D521_1860 3c470e6c8ccd4a14c250404ae5f12e4d 244 SUPERFAMILY SSF69593 10 238 3.79E-39 T 14-10-2018 D521_1860 3c470e6c8ccd4a14c250404ae5f12e4d 244 Pfam PF01553 Acyltransferase 60 187 3.1E-22 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 D521_1186 65721a268bffa46c48eb59d69439eec5 351 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 145 350 6.0E-50 T 14-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 D521_1186 65721a268bffa46c48eb59d69439eec5 351 Pfam PF01292 Prokaryotic cytochrome b561 148 331 4.8E-16 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 D521_1186 65721a268bffa46c48eb59d69439eec5 351 SUPERFAMILY SSF81342 143 349 4.87E-40 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 D521_1186 65721a268bffa46c48eb59d69439eec5 351 Gene3D G3DSA:1.20.950.20 141 351 1.6E-59 T 14-10-2018 D521_1862 93bf7c0c531ebccd1a1e2cbdbb3077aa 339 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 7 334 33.579 T 14-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 D521_1862 93bf7c0c531ebccd1a1e2cbdbb3077aa 339 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 58 327 9.0E-100 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 D521_1862 93bf7c0c531ebccd1a1e2cbdbb3077aa 339 Gene3D G3DSA:3.40.718.10 3 336 5.2E-111 T 14-10-2018 D521_1862 93bf7c0c531ebccd1a1e2cbdbb3077aa 339 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 10 331 2.2E-110 T 14-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 D521_1862 93bf7c0c531ebccd1a1e2cbdbb3077aa 339 SUPERFAMILY SSF53659 10 333 1.09E-92 T 14-10-2018 D521_0282 7ff4c43bcfb31f80f2032d93f75615cd 148 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 5.8E-58 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 D521_0282 7ff4c43bcfb31f80f2032d93f75615cd 148 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 148 82.794 T 14-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 D521_0282 7ff4c43bcfb31f80f2032d93f75615cd 148 Pfam PF03477 ATP cone domain 51 135 1.6E-14 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 D521_1225 317df799591c823e720a2b13cadc7bb0 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 14-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 D521_1225 317df799591c823e720a2b13cadc7bb0 488 SUPERFAMILY SSF54631 94 202 6.1E-29 T 14-10-2018 D521_1225 317df799591c823e720a2b13cadc7bb0 488 SMART SM00116 156 204 2.6E-10 T 14-10-2018 IPR000644 CBS domain D521_1225 317df799591c823e720a2b13cadc7bb0 488 SMART SM00116 95 142 5.2E-9 T 14-10-2018 IPR000644 CBS domain D521_1225 317df799591c823e720a2b13cadc7bb0 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 474 1.7E-164 T 14-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 D521_1225 317df799591c823e720a2b13cadc7bb0 488 SUPERFAMILY SSF51412 2 478 4.84E-127 T 14-10-2018 D521_1225 317df799591c823e720a2b13cadc7bb0 488 SMART SM01240 6 474 0.0 T 14-10-2018 D521_1225 317df799591c823e720a2b13cadc7bb0 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 487 84.672 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 D521_1225 317df799591c823e720a2b13cadc7bb0 488 PIRSF PIRSF000130 1 488 1.7E-206 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 D521_1225 317df799591c823e720a2b13cadc7bb0 488 Gene3D G3DSA:3.20.20.70 1 487 1.1E-216 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1225 317df799591c823e720a2b13cadc7bb0 488 Pfam PF00571 CBS domain 153 202 8.1E-10 T 14-10-2018 IPR000644 CBS domain D521_1225 317df799591c823e720a2b13cadc7bb0 488 Pfam PF00571 CBS domain 94 138 3.2E-8 T 14-10-2018 IPR000644 CBS domain D521_1225 317df799591c823e720a2b13cadc7bb0 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 456 4.4E-191 T 14-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 D521_1539 8634d3643cc174ff142dbfea6158c081 143 SUPERFAMILY SSF82093 29 134 8.37E-39 T 14-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 D521_1539 8634d3643cc174ff142dbfea6158c081 143 Pfam PF03100 CcmE 4 128 3.7E-46 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 D521_1539 8634d3643cc174ff142dbfea6158c081 143 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 138 32.183 T 14-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 D521_1539 8634d3643cc174ff142dbfea6158c081 143 Gene3D G3DSA:2.40.50.140 29 134 1.1E-38 T 14-10-2018 D521_0375 50a5ddba833de6c739a5e195bb84dd3f 312 Gene3D G3DSA:3.60.15.10 15 242 2.4E-35 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_0375 50a5ddba833de6c739a5e195bb84dd3f 312 Pfam PF00753 Metallo-beta-lactamase superfamily 20 211 5.8E-19 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0375 50a5ddba833de6c739a5e195bb84dd3f 312 SUPERFAMILY SSF56281 21 232 2.3E-39 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_0375 50a5ddba833de6c739a5e195bb84dd3f 312 SMART SM00849 24 211 1.4E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0480 e0f07bcd3b8fd1d3b8281e580090e140 587 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0480 e0f07bcd3b8fd1d3b8281e580090e140 587 SUPERFAMILY SSF52540 331 584 6.32E-88 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0480 e0f07bcd3b8fd1d3b8281e580090e140 587 SUPERFAMILY SSF90123 11 323 4.32E-70 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 D521_0480 e0f07bcd3b8fd1d3b8281e580090e140 587 Pfam PF00664 ABC transporter transmembrane region 26 293 1.3E-43 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 D521_0480 e0f07bcd3b8fd1d3b8281e580090e140 587 Pfam PF00005 ABC transporter 361 513 1.7E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0480 e0f07bcd3b8fd1d3b8281e580090e140 587 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 10 585 6.4E-229 T 14-10-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 D521_0480 e0f07bcd3b8fd1d3b8281e580090e140 587 SMART SM00382 370 559 1.7E-18 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0480 e0f07bcd3b8fd1d3b8281e580090e140 587 Gene3D G3DSA:1.20.1560.10 1 326 7.1E-73 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 D521_0480 e0f07bcd3b8fd1d3b8281e580090e140 587 Gene3D G3DSA:3.40.50.300 333 586 6.2E-89 T 14-10-2018 D521_1411 093745a37daf475efb77fc4736c2158e 191 PIRSF PIRSF000847 1 191 3.9E-46 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 D521_1411 093745a37daf475efb77fc4736c2158e 191 Gene3D G3DSA:1.20.120.1760 5 185 2.6E-12 T 14-10-2018 D521_1411 093745a37daf475efb77fc4736c2158e 191 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 54 76 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 D521_1411 093745a37daf475efb77fc4736c2158e 191 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 76 2.2E-15 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 D521_1411 093745a37daf475efb77fc4736c2158e 191 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 3 188 1.7E-51 T 14-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 D521_0286 0015eb4f6369d8ac0ad0ee3abbc98f85 251 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 8 243 2.0E-87 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 D521_0286 0015eb4f6369d8ac0ad0ee3abbc98f85 251 SUPERFAMILY SSF53448 8 249 4.9E-57 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0286 0015eb4f6369d8ac0ad0ee3abbc98f85 251 Pfam PF02348 Cytidylyltransferase 10 223 8.4E-57 T 14-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 D521_0286 0015eb4f6369d8ac0ad0ee3abbc98f85 251 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 6 250 41.47 T 14-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 D521_0286 0015eb4f6369d8ac0ad0ee3abbc98f85 251 Gene3D G3DSA:3.90.550.10 2 250 4.3E-93 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0121 666898d562bd9c1757af317bea2ef3d9 200 PRINTS PR00162 Rieske 2Fe-2S subunit signature 122 133 4.9E-6 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 D521_0121 666898d562bd9c1757af317bea2ef3d9 200 PRINTS PR00162 Rieske 2Fe-2S subunit signature 154 166 4.9E-6 T 14-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 D521_0121 666898d562bd9c1757af317bea2ef3d9 200 SUPERFAMILY SSF50022 31 194 6.16E-41 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 D521_0121 666898d562bd9c1757af317bea2ef3d9 200 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 10 195 2.0E-66 T 14-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 D521_0121 666898d562bd9c1757af317bea2ef3d9 200 Gene3D G3DSA:1.20.5.510 1 40 7.3E-6 T 14-10-2018 D521_0121 666898d562bd9c1757af317bea2ef3d9 200 Pfam PF00355 Rieske [2Fe-2S] domain 113 182 1.8E-10 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 D521_0121 666898d562bd9c1757af317bea2ef3d9 200 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 1 40 9.5E-16 T 14-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 D521_0121 666898d562bd9c1757af317bea2ef3d9 200 Gene3D G3DSA:2.102.10.10 43 195 8.4E-47 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 878 0.0 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 896 14.562 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 Gene3D G3DSA:3.40.50.620 285 513 3.7E-60 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 Pfam PF08264 Anticodon-binding domain of tRNA 618 771 6.3E-40 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 1 565 4.2E-194 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 SUPERFAMILY SSF47323 576 845 8.04E-61 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 SUPERFAMILY SSF52374 1 575 9.01E-119 T 14-10-2018 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 SUPERFAMILY SSF50677 141 292 7.72E-63 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 PRINTS PR00986 Valyl-tRNA synthetase signature 440 458 9.9E-29 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 PRINTS PR00986 Valyl-tRNA synthetase signature 180 197 9.9E-29 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 PRINTS PR00986 Valyl-tRNA synthetase signature 296 309 9.9E-29 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 PRINTS PR00986 Valyl-tRNA synthetase signature 409 430 9.9E-29 T 14-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 Gene3D G3DSA:1.10.730.10 518 766 8.9E-67 T 14-10-2018 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 Gene3D G3DSA:3.40.50.620 1 138 5.6E-42 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 Gene3D G3DSA:1.10.287.380 825 896 1.0E-15 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 SUPERFAMILY SSF46589 831 895 2.09E-16 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 Gene3D G3DSA:3.90.740.10 143 284 2.4E-53 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 D521_1705 2c8459daf787fe18f9a862a4fb1902d1 896 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 831 896 3.1E-18 T 14-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 SUPERFAMILY SSF82866 803 1028 3.01E-56 T 14-10-2018 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 SUPERFAMILY SSF82693 43 128 6.02E-19 T 14-10-2018 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 Gene3D G3DSA:3.30.70.1430 567 668 7.5E-285 T 14-10-2018 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 Gene3D G3DSA:3.30.70.1430 42 816 7.5E-285 T 14-10-2018 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 Gene3D G3DSA:1.20.1640.10 513 1021 7.5E-285 T 14-10-2018 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 Gene3D G3DSA:3.30.2090.10 720 808 7.5E-285 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 Gene3D G3DSA:3.30.2090.10 188 279 7.5E-285 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 6.9E-40 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 PRINTS PR00702 Acriflavin resistance protein family signature 396 420 6.9E-40 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 PRINTS PR00702 Acriflavin resistance protein family signature 368 389 6.9E-40 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 PRINTS PR00702 Acriflavin resistance protein family signature 478 501 6.9E-40 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 PRINTS PR00702 Acriflavin resistance protein family signature 620 634 6.9E-40 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 PRINTS PR00702 Acriflavin resistance protein family signature 341 364 6.9E-40 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 6.9E-40 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 6.9E-40 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 Gene3D G3DSA:3.30.70.1320 135 335 7.5E-285 T 14-10-2018 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 SUPERFAMILY SSF82714 191 274 3.14E-14 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1028 0.0 T 14-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 SUPERFAMILY SSF82693 567 662 1.06E-7 T 14-10-2018 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 Pfam PF00873 AcrB/AcrD/AcrF family 5 1024 9.7E-290 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 Gene3D G3DSA:3.30.70.1440 669 866 7.5E-285 T 14-10-2018 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 SUPERFAMILY SSF82866 299 505 8.37E-42 T 14-10-2018 D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 SUPERFAMILY SSF82714 721 803 1.57E-18 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0393 8dd3a9cb1d43ce8f41c0354abf8e8a94 1031 Gene3D G3DSA:1.20.1640.10 15 512 7.5E-285 T 14-10-2018 D521_1192 30b10f8aa36cd993c225f1600905a831 696 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 190 201 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1192 30b10f8aa36cd993c225f1600905a831 696 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 605 616 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1192 30b10f8aa36cd993c225f1600905a831 696 SUPERFAMILY SSF54862 286 657 2.17E-43 T 14-10-2018 D521_1192 30b10f8aa36cd993c225f1600905a831 696 Pfam PF12838 4Fe-4S dicluster domain 311 357 1.8E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1192 30b10f8aa36cd993c225f1600905a831 696 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 343 354 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1192 30b10f8aa36cd993c225f1600905a831 696 Pfam PF00037 4Fe-4S binding domain 185 206 1.4E-8 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1192 30b10f8aa36cd993c225f1600905a831 696 Gene3D G3DSA:3.30.70.20 179 236 4.0E-8 T 14-10-2018 D521_1192 30b10f8aa36cd993c225f1600905a831 696 Gene3D G3DSA:3.30.70.20 307 405 4.0E-13 T 14-10-2018 D521_1192 30b10f8aa36cd993c225f1600905a831 696 Gene3D G3DSA:3.30.70.20 567 645 1.0E-10 T 14-10-2018 D521_1192 30b10f8aa36cd993c225f1600905a831 696 SUPERFAMILY SSF54862 184 240 1.14E-13 T 14-10-2018 D521_1192 30b10f8aa36cd993c225f1600905a831 696 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 574 585 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1192 30b10f8aa36cd993c225f1600905a831 696 Pfam PF13187 4Fe-4S dicluster domain 573 619 1.2E-6 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 SMART SM00278 436 455 5.2 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 SMART SM00278 470 489 86.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 SMART SM00278 502 521 110.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 SMART SM00278 534 553 26.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 2 308 2.0E-121 T 14-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 321 336 - T 14-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 1 649 8.7E-257 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Gene3D G3DSA:3.30.470.90 59 307 3.3E-98 T 14-10-2018 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 SUPERFAMILY SSF52113 584 655 1.11E-18 T 14-10-2018 IPR036420 BRCT domain superfamily D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Gene3D G3DSA:1.10.150.20 422 495 9.5E-30 T 14-10-2018 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Pfam PF12826 Helix-hairpin-helix motif 500 563 7.8E-26 T 14-10-2018 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 104 133 - T 14-10-2018 IPR018239 NAD-dependent DNA ligase, active site D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 SUPERFAMILY SSF47781 393 573 1.59E-62 T 14-10-2018 IPR010994 RuvA domain 2-like D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Gene3D G3DSA:1.10.287.610 1 58 5.7E-21 T 14-10-2018 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 312 386 1.4E-34 T 14-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Gene3D G3DSA:3.40.50.10190 573 656 2.0E-27 T 14-10-2018 IPR036420 BRCT domain superfamily D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 SUPERFAMILY SSF50249 308 388 1.13E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 397 424 5.6E-9 T 14-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Pfam PF14520 Helix-hairpin-helix domain 438 490 1.5E-5 T 14-10-2018 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 SMART SM00292 581 656 1.8E-11 T 14-10-2018 IPR001357 BRCT domain D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 PIRSF PIRSF001604 1 656 1.6E-245 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 SUPERFAMILY SSF56091 1 306 3.7E-112 T 14-10-2018 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 SMART SM00532 1 438 9.0E-256 T 14-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Hamap MF_01588 DNA ligase [ligA]. 1 655 53.406 T 14-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Gene3D G3DSA:2.20.70.80 381 421 1.6E-17 T 14-10-2018 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Gene3D G3DSA:2.40.50.140 308 380 4.1E-34 T 14-10-2018 D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 586 654 1.5E-12 T 14-10-2018 IPR001357 BRCT domain D521_1265 3f3d6bdc10d177105590863ee7fd98f4 656 Gene3D G3DSA:1.10.150.20 496 572 2.8E-30 T 14-10-2018 D521_1541 ad00cb4abb7f96efc9946468be8cacd8 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 110 130 3.4E-46 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1541 ad00cb4abb7f96efc9946468be8cacd8 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 166 192 3.4E-46 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1541 ad00cb4abb7f96efc9946468be8cacd8 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 214 238 3.4E-46 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1541 ad00cb4abb7f96efc9946468be8cacd8 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 55 72 3.4E-46 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1541 ad00cb4abb7f96efc9946468be8cacd8 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 131 151 3.4E-46 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1541 ad00cb4abb7f96efc9946468be8cacd8 256 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 72 92 3.4E-46 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1541 ad00cb4abb7f96efc9946468be8cacd8 256 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 55 238 9.2E-69 T 14-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1541 ad00cb4abb7f96efc9946468be8cacd8 256 Pfam PF01578 Cytochrome C assembly protein 34 194 1.2E-24 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 ProSitePatterns PS01229 Hypothetical cof family signature 2. 652 674 - T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 Gene3D G3DSA:3.40.50.1000 417 704 1.4E-76 T 14-10-2018 IPR023214 HAD superfamily D521_1199 0173b0ca2bbdba231ec526964628ce26 762 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 161 754 1.6E-167 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 SUPERFAMILY SSF81665 187 428 9.02E-13 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 Pfam PF00122 E1-E2 ATPase 247 415 1.9E-49 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 ProSitePatterns PS01047 Heavy-metal-associated domain. 16 45 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 SUPERFAMILY SSF81653 248 336 1.27E-23 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 Gene3D G3DSA:3.40.1110.10 447 580 1.4E-76 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 438 444 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 PRINTS PR00943 Copper-transporting ATPase signature 194 213 4.2E-9 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 PRINTS PR00943 Copper-transporting ATPase signature 55 75 4.2E-9 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 PRINTS PR00943 Copper-transporting ATPase signature 359 373 4.2E-9 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 PRINTS PR00943 Copper-transporting ATPase signature 419 434 4.2E-9 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 PRINTS PR00943 Copper-transporting ATPase signature 146 165 4.2E-9 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 Gene3D G3DSA:2.70.150.20 211 340 6.1E-35 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 Pfam PF00403 Heavy-metal-associated domain 13 74 1.4E-15 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 595 605 1.1E-23 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 436 450 1.1E-23 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 675 687 1.1E-23 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 286 300 1.1E-23 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 652 671 1.1E-23 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 Pfam PF00702 haloacid dehalogenase-like hydrolase 433 666 5.7E-37 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 572 741 3.5E-36 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 196 471 9.8E-43 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 Gene3D G3DSA:3.30.70.100 10 82 2.6E-21 T 14-10-2018 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 SUPERFAMILY SSF55008 7 76 6.28E-21 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 D521_1199 0173b0ca2bbdba231ec526964628ce26 762 SUPERFAMILY SSF56784 434 752 6.68E-51 T 14-10-2018 IPR036412 HAD-like superfamily D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 SUPERFAMILY SSF82693 139 319 1.05E-17 T 14-10-2018 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 SUPERFAMILY SSF82714 717 800 2.62E-14 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 Gene3D G3DSA:1.20.1640.10 512 1019 3.8E-261 T 14-10-2018 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 Gene3D G3DSA:3.30.2090.10 719 805 3.8E-261 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 Gene3D G3DSA:3.30.70.1430 567 667 3.8E-261 T 14-10-2018 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 PRINTS PR00702 Acriflavin resistance protein family signature 388 412 7.9E-24 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 PRINTS PR00702 Acriflavin resistance protein family signature 470 493 7.9E-24 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 PRINTS PR00702 Acriflavin resistance protein family signature 360 381 7.9E-24 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 PRINTS PR00702 Acriflavin resistance protein family signature 40 58 7.9E-24 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 PRINTS PR00702 Acriflavin resistance protein family signature 12 36 7.9E-24 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 PRINTS PR00702 Acriflavin resistance protein family signature 333 356 7.9E-24 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 1 1027 1.5E-231 T 14-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 Gene3D G3DSA:3.30.70.1440 668 864 3.8E-261 T 14-10-2018 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 Gene3D G3DSA:3.30.70.1320 136 328 3.8E-261 T 14-10-2018 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 SUPERFAMILY SSF82866 293 501 9.29E-34 T 14-10-2018 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 Gene3D G3DSA:3.30.2090.10 182 274 3.8E-261 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 Pfam PF00873 AcrB/AcrD/AcrF family 6 1021 8.9E-251 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 SUPERFAMILY SSF82714 185 266 2.35E-15 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 SUPERFAMILY SSF82693 43 126 4.97E-21 T 14-10-2018 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 SUPERFAMILY SSF82693 563 657 9.16E-7 T 14-10-2018 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 Gene3D G3DSA:3.30.70.1430 42 813 3.8E-261 T 14-10-2018 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 SUPERFAMILY SSF82866 798 1025 7.06E-43 T 14-10-2018 D521_1672 1662c5f1ecea50db2e6cb45a29d02099 1040 Gene3D G3DSA:1.20.1640.10 14 511 3.8E-261 T 14-10-2018 D521_1717 73cc170268b7290f9d513f979cefe72e 284 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 228 233 - T 14-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site D521_1717 73cc170268b7290f9d513f979cefe72e 284 TIGRFAM TIGR00608 radc: DNA repair protein RadC 66 278 8.0E-68 T 14-10-2018 IPR001405 Uncharacterised protein family UPF0758 D521_1717 73cc170268b7290f9d513f979cefe72e 284 SUPERFAMILY SSF47781 72 142 4.08E-9 T 14-10-2018 IPR010994 RuvA domain 2-like D521_1717 73cc170268b7290f9d513f979cefe72e 284 SUPERFAMILY SSF102712 204 247 1.7E-5 T 14-10-2018 D521_1717 73cc170268b7290f9d513f979cefe72e 284 Pfam PF04002 RadC-like JAB domain 159 277 5.8E-41 T 14-10-2018 IPR025657 RadC-like JAB domain D521_1717 73cc170268b7290f9d513f979cefe72e 284 Gene3D G3DSA:3.40.140.10 154 279 3.3E-41 T 14-10-2018 D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 SUPERFAMILY SSF69055 300 393 2.62E-29 T 14-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 Gene3D G3DSA:1.10.1740.10 311 395 2.3E-27 T 14-10-2018 D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 6 390 46.804 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6 134 4.9E-46 T 14-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 PIRSF PIRSF006205 3 396 5.4E-152 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 Gene3D G3DSA:3.40.50.720 1 152 5.2E-54 T 14-10-2018 D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 148 237 6.1E-38 T 14-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 SUPERFAMILY SSF55347 128 272 3.07E-61 T 14-10-2018 D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 Pfam PF13288 DXP reductoisomerase C-terminal domain 269 385 1.1E-38 T 14-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 SUPERFAMILY SSF51735 4 152 1.08E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1255 33e6920ccb6f8d49e45d9cdc8334cb3d 396 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3 389 7.4E-154 T 14-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 Pfam PF13180 PDZ domain 279 369 1.5E-16 T 14-10-2018 IPR001478 PDZ domain GO:0005515 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 Gene3D G3DSA:2.40.10.120 32 271 1.2E-83 T 14-10-2018 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 SMART SM00228 393 472 0.061 T 14-10-2018 IPR001478 PDZ domain GO:0005515 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 SMART SM00228 278 360 2.8E-11 T 14-10-2018 IPR001478 PDZ domain GO:0005515 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 SUPERFAMILY SSF50156 394 481 6.26E-10 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 SUPERFAMILY SSF50156 236 360 6.7E-23 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 Pfam PF13365 Trypsin-like peptidase domain 108 239 4.0E-36 T 14-10-2018 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 PRINTS PR00834 HtrA/DegQ protease family signature 138 158 8.8E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 PRINTS PR00834 HtrA/DegQ protease family signature 318 330 8.8E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 PRINTS PR00834 HtrA/DegQ protease family signature 210 227 8.8E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 PRINTS PR00834 HtrA/DegQ protease family signature 117 129 8.8E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 PRINTS PR00834 HtrA/DegQ protease family signature 232 249 8.8E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 PRINTS PR00834 HtrA/DegQ protease family signature 178 202 8.8E-51 T 14-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 Gene3D G3DSA:2.30.42.10 273 379 3.9E-24 T 14-10-2018 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 Gene3D G3DSA:2.30.42.10 391 482 7.9E-11 T 14-10-2018 D521_1423 4afdea715c34ad05edb71cc2d562d968 482 SUPERFAMILY SSF50494 32 269 6.5E-66 T 14-10-2018 IPR009003 Peptidase S1, PA clan D521_1423 4afdea715c34ad05edb71cc2d562d968 482 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 33 477 1.9E-147 T 14-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 D521_2011 c99f5c1319f8ae3a7efbf73eb678b094 422 Pfam PF07690 Major Facilitator Superfamily 2 364 3.7E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_2011 c99f5c1319f8ae3a7efbf73eb678b094 422 Gene3D G3DSA:1.20.1250.20 1 165 2.2E-6 T 14-10-2018 D521_2011 c99f5c1319f8ae3a7efbf73eb678b094 422 Gene3D G3DSA:1.20.1250.20 219 413 2.4E-11 T 14-10-2018 D521_2011 c99f5c1319f8ae3a7efbf73eb678b094 422 SUPERFAMILY SSF103473 2 406 5.23E-30 T 14-10-2018 IPR036259 MFS transporter superfamily D521_0770 fc94fdd31302528169b2612a1393ba88 236 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 212 9.6E-59 T 14-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_0770 fc94fdd31302528169b2612a1393ba88 236 SMART SM00479 2 174 4.4E-47 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III D521_0770 fc94fdd31302528169b2612a1393ba88 236 Pfam PF00929 Exonuclease 4 165 2.3E-35 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III D521_0770 fc94fdd31302528169b2612a1393ba88 236 SUPERFAMILY SSF53098 1 176 3.53E-53 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_0770 fc94fdd31302528169b2612a1393ba88 236 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 229 7.8E-85 T 14-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_0770 fc94fdd31302528169b2612a1393ba88 236 Gene3D G3DSA:3.30.420.10 1 179 1.4E-52 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_0281 07cbf2316cb12d626691caa15fb62232 414 PIRSF PIRSF000412 1 414 3.6E-165 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 D521_0281 07cbf2316cb12d626691caa15fb62232 414 Pfam PF00464 Serine hydroxymethyltransferase 8 383 4.6E-173 T 14-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 D521_0281 07cbf2316cb12d626691caa15fb62232 414 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 414 52.43 T 14-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 D521_0281 07cbf2316cb12d626691caa15fb62232 414 Gene3D G3DSA:3.90.1150.10 10 392 1.0E-183 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_0281 07cbf2316cb12d626691caa15fb62232 414 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 14-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 D521_0281 07cbf2316cb12d626691caa15fb62232 414 SUPERFAMILY SSF53383 6 414 1.17E-180 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0281 07cbf2316cb12d626691caa15fb62232 414 Gene3D G3DSA:3.40.640.10 37 286 1.0E-183 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0992 e76be1cbf976cf6174d7cddd6502aae9 512 PIRSF PIRSF000485 1 483 7.3E-159 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 D521_0992 e76be1cbf976cf6174d7cddd6502aae9 512 SUPERFAMILY SSF53271 252 484 6.82E-73 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like D521_0992 e76be1cbf976cf6174d7cddd6502aae9 512 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 466 44.816 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 D521_0992 e76be1cbf976cf6174d7cddd6502aae9 512 SUPERFAMILY SSF56235 2 259 8.23E-67 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_0992 e76be1cbf976cf6174d7cddd6502aae9 512 Gene3D G3DSA:3.60.20.10 2 414 8.4E-149 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_0992 e76be1cbf976cf6174d7cddd6502aae9 512 Gene3D G3DSA:3.40.50.2020 279 443 8.4E-149 T 14-10-2018 D521_0992 e76be1cbf976cf6174d7cddd6502aae9 512 Pfam PF00156 Phosphoribosyl transferase domain 281 395 1.2E-11 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 D521_0992 e76be1cbf976cf6174d7cddd6502aae9 512 Pfam PF13537 Glutamine amidotransferase domain 81 214 2.7E-15 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain D521_0992 e76be1cbf976cf6174d7cddd6502aae9 512 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 466 4.8E-155 T 14-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 D521_1258 edd31c76c2b73609a7f6249be8ccd35e 186 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 186 1.2E-70 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 D521_1258 edd31c76c2b73609a7f6249be8ccd35e 186 Gene3D G3DSA:3.30.1360.40 32 106 9.2E-66 T 14-10-2018 D521_1258 edd31c76c2b73609a7f6249be8ccd35e 186 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 186 27.229 T 14-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 D521_1258 edd31c76c2b73609a7f6249be8ccd35e 186 Gene3D G3DSA:1.10.132.20 13 183 9.2E-66 T 14-10-2018 D521_1258 edd31c76c2b73609a7f6249be8ccd35e 186 Pfam PF01765 Ribosome recycling factor 21 184 2.0E-61 T 14-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 D521_1258 edd31c76c2b73609a7f6249be8ccd35e 186 SUPERFAMILY SSF55194 6 185 5.76E-69 T 14-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 D521_0523 583830d931edadc18fd11c9199c2d062 190 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 9 187 22.218 T 14-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 D521_0523 583830d931edadc18fd11c9199c2d062 190 Pfam PF04345 Chorismate lyase 10 183 1.2E-24 T 14-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 D521_0523 583830d931edadc18fd11c9199c2d062 190 SUPERFAMILY SSF64288 19 187 8.9E-34 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily D521_0523 583830d931edadc18fd11c9199c2d062 190 Gene3D G3DSA:3.40.1410.10 6 187 1.7E-40 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily D521_1207 739f025a2914f414891f181f22903200 314 Pfam PF02016 LD-carboxypeptidase 4 301 1.1E-65 T 14-10-2018 IPR003507 Peptidase family S66 D521_1207 739f025a2914f414891f181f22903200 314 Gene3D G3DSA:3.40.50.10740 2 159 2.0E-30 T 14-10-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal D521_1207 739f025a2914f414891f181f22903200 314 PIRSF PIRSF028757 1 314 1.4E-68 T 14-10-2018 IPR003507 Peptidase family S66 D521_1207 739f025a2914f414891f181f22903200 314 SUPERFAMILY SSF52317 3 165 2.56E-29 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_1207 739f025a2914f414891f181f22903200 314 SUPERFAMILY SSF141986 144 305 2.75E-40 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily D521_1207 739f025a2914f414891f181f22903200 314 Gene3D G3DSA:3.50.30.60 168 308 4.2E-42 T 14-10-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain superfamily D521_1180 43f5f178d912f2ab524f79341ffb782c 491 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 22 491 2.0E-122 T 14-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 PIRSF PIRSF000850 311 383 0.0095 T 14-10-2018 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 PIRSF PIRSF000850 117 257 1.4 T 14-10-2018 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 PIRSF PIRSF000850 387 467 1.1 T 14-10-2018 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 SMART SM00155 404 431 0.0098 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 SMART SM00155 226 253 0.0013 T 14-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 Pfam PF13091 PLD-like domain 332 456 4.5E-26 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 Pfam PF13091 PLD-like domain 142 287 7.9E-16 T 14-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 SUPERFAMILY SSF56024 114 320 1.22E-47 T 14-10-2018 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 SUPERFAMILY SSF56024 294 477 1.19E-42 T 14-10-2018 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 Hamap MF_00190 Cardiolipin synthase A [clsA]. 9 491 45.099 T 14-10-2018 IPR030840 Cardiolipin synthase A GO:0008808|GO:0016780|GO:0032049 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 Gene3D G3DSA:3.30.870.10 121 314 5.8E-35 T 14-10-2018 D521_1180 43f5f178d912f2ab524f79341ffb782c 491 Gene3D G3DSA:3.30.870.10 315 487 7.4E-29 T 14-10-2018 D521_0629 33b384d38f61424db2c92a02e8e32deb 299 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 52 272 1.2E-33 T 14-10-2018 D521_0629 33b384d38f61424db2c92a02e8e32deb 299 Gene3D G3DSA:3.40.190.10 130 230 2.6E-22 T 14-10-2018 D521_0629 33b384d38f61424db2c92a02e8e32deb 299 Gene3D G3DSA:3.40.190.10 52 261 2.6E-22 T 14-10-2018 D521_0629 33b384d38f61424db2c92a02e8e32deb 299 SUPERFAMILY SSF53850 44 263 1.69E-15 T 14-10-2018 D521_1580 c6e16acee01aea566ea1bb0f681d682b 310 Gene3D G3DSA:3.40.50.620 3 183 6.3E-54 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1580 c6e16acee01aea566ea1bb0f681d682b 310 SUPERFAMILY SSF52402 3 186 1.0E-54 T 14-10-2018 D521_1580 c6e16acee01aea566ea1bb0f681d682b 310 PIRSF PIRSF000089 1 310 5.8E-105 T 14-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 D521_1580 c6e16acee01aea566ea1bb0f681d682b 310 Gene3D G3DSA:3.40.50.1220 184 310 8.5E-56 T 14-10-2018 D521_1580 c6e16acee01aea566ea1bb0f681d682b 310 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 254 280 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 D521_1580 c6e16acee01aea566ea1bb0f681d682b 310 SUPERFAMILY SSF52467 187 309 1.91E-45 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily D521_1580 c6e16acee01aea566ea1bb0f681d682b 310 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 273 1.9E-34 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 D521_1580 c6e16acee01aea566ea1bb0f681d682b 310 Pfam PF01012 Electron transfer flavoprotein domain 4 171 2.1E-37 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 D521_1580 c6e16acee01aea566ea1bb0f681d682b 310 SMART SM00893 3 182 4.1E-55 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 SUPERFAMILY SSF48013 23 156 4.8E-9 T 14-10-2018 IPR035926 NusB-like superfamily D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 Pfam PF01029 NusB family 27 132 3.6E-5 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 329 340 - T 14-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 SUPERFAMILY SSF53335 145 434 6.23E-59 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 Gene3D G3DSA:3.30.70.1170 180 242 5.1E-15 T 14-10-2018 D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 Pfam PF01189 16S rRNA methyltransferase RsmB/F 252 408 9.1E-50 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 21 435 1.9E-81 T 14-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 Gene3D G3DSA:1.10.940.10 14 142 6.8E-10 T 14-10-2018 IPR035926 NusB-like superfamily D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 Gene3D G3DSA:3.40.50.150 243 435 6.5E-54 T 14-10-2018 D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 330 342 6.3E-25 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 380 396 6.3E-25 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 417 434 6.3E-25 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 263 273 6.3E-25 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase D521_2107 1ad4178d2e2c2ee7c1be4a324b188548 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 234 248 6.3E-25 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase D521_1366 492b91ecf7a13ce39c044ba625051126 864 SUPERFAMILY SSF81923 4 156 3.24E-38 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 D521_1366 492b91ecf7a13ce39c044ba625051126 864 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 857 0.0 T 14-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 D521_1366 492b91ecf7a13ce39c044ba625051126 864 SMART SM00382 604 746 7.4E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1366 492b91ecf7a13ce39c044ba625051126 864 SMART SM00382 198 343 1.7E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1366 492b91ecf7a13ce39c044ba625051126 864 SUPERFAMILY SSF52540 159 521 2.65E-98 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1366 492b91ecf7a13ce39c044ba625051126 864 Gene3D G3DSA:3.40.50.300 158 347 2.5E-74 T 14-10-2018 D521_1366 492b91ecf7a13ce39c044ba625051126 864 Gene3D G3DSA:3.40.50.300 348 551 1.3E-67 T 14-10-2018 D521_1366 492b91ecf7a13ce39c044ba625051126 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 682 700 4.3E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 D521_1366 492b91ecf7a13ce39c044ba625051126 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 715 729 4.3E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 D521_1366 492b91ecf7a13ce39c044ba625051126 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 671 4.3E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 D521_1366 492b91ecf7a13ce39c044ba625051126 864 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 608 626 4.3E-43 T 14-10-2018 IPR001270 ClpA/B family GO:0005524 D521_1366 492b91ecf7a13ce39c044ba625051126 864 Gene3D G3DSA:1.10.8.60 772 863 9.5E-25 T 14-10-2018 D521_1366 492b91ecf7a13ce39c044ba625051126 864 Gene3D G3DSA:3.40.50.300 557 770 1.6E-89 T 14-10-2018 D521_1366 492b91ecf7a13ce39c044ba625051126 864 SUPERFAMILY SSF52540 553 854 2.89E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1366 492b91ecf7a13ce39c044ba625051126 864 Pfam PF07724 AAA domain (Cdc48 subfamily) 603 766 2.6E-56 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 D521_1366 492b91ecf7a13ce39c044ba625051126 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 94 145 3.5E-8 T 14-10-2018 IPR004176 Clp, N-terminal D521_1366 492b91ecf7a13ce39c044ba625051126 864 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 68 6.0E-16 T 14-10-2018 IPR004176 Clp, N-terminal D521_1366 492b91ecf7a13ce39c044ba625051126 864 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 336 1.2E-13 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 D521_1366 492b91ecf7a13ce39c044ba625051126 864 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 14-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 D521_1366 492b91ecf7a13ce39c044ba625051126 864 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 638 656 - T 14-10-2018 IPR028299 ClpA/B, conserved site 2 D521_1366 492b91ecf7a13ce39c044ba625051126 864 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 772 851 5.1E-24 T 14-10-2018 IPR019489 Clp ATPase, C-terminal D521_1366 492b91ecf7a13ce39c044ba625051126 864 SMART SM01086 772 862 1.7E-32 T 14-10-2018 IPR019489 Clp ATPase, C-terminal D521_1366 492b91ecf7a13ce39c044ba625051126 864 Gene3D G3DSA:1.10.1780.10 1 150 4.9E-29 T 14-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 D521_0388 58f8d375553e59622903d0153b105d51 322 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 7 318 7.1E-113 T 14-10-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily D521_0012 816f64b8f02ba5be5ee87976c1f55f0b 220 Gene3D G3DSA:3.40.50.150 2 220 1.6E-61 T 14-10-2018 D521_0012 816f64b8f02ba5be5ee87976c1f55f0b 220 Pfam PF02527 rRNA small subunit methyltransferase G 22 203 7.8E-47 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 D521_0012 816f64b8f02ba5be5ee87976c1f55f0b 220 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 211 25.95 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 D521_0012 816f64b8f02ba5be5ee87976c1f55f0b 220 SUPERFAMILY SSF53335 4 213 6.94E-34 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0012 816f64b8f02ba5be5ee87976c1f55f0b 220 PIRSF PIRSF003078 1 217 7.1E-52 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 D521_0012 816f64b8f02ba5be5ee87976c1f55f0b 220 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 26 211 2.1E-46 T 14-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 D521_1946 a8827ba4bc1f8bc704703ab31af3e7ea 229 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 3 228 4.9E-109 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 D521_1946 a8827ba4bc1f8bc704703ab31af3e7ea 229 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 D521_1946 a8827ba4bc1f8bc704703ab31af3e7ea 229 SMART SM00855 3 189 1.9E-27 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 D521_1946 a8827ba4bc1f8bc704703ab31af3e7ea 229 PIRSF PIRSF000709 1 110 3.4E-7 T 14-10-2018 D521_1946 a8827ba4bc1f8bc704703ab31af3e7ea 229 PIRSF PIRSF000709 134 220 0.014 T 14-10-2018 D521_1946 a8827ba4bc1f8bc704703ab31af3e7ea 229 Gene3D G3DSA:3.40.50.1240 1 229 4.0E-88 T 14-10-2018 IPR029033 Histidine phosphatase superfamily D521_1946 a8827ba4bc1f8bc704703ab31af3e7ea 229 SUPERFAMILY SSF53254 1 228 3.85E-78 T 14-10-2018 IPR029033 Histidine phosphatase superfamily D521_1946 a8827ba4bc1f8bc704703ab31af3e7ea 229 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 133 218 1.1E-6 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 D521_1946 a8827ba4bc1f8bc704703ab31af3e7ea 229 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 127 1.4E-30 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 D521_1946 a8827ba4bc1f8bc704703ab31af3e7ea 229 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 1 228 45.195 T 14-10-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 D521_0192 bbf06f5f883801d6bc90b9ca0e52b832 339 SUPERFAMILY SSF48179 199 320 6.12E-29 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_0192 bbf06f5f883801d6bc90b9ca0e52b832 339 Gene3D G3DSA:1.10.1040.10 199 330 2.2E-40 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 D521_0192 bbf06f5f883801d6bc90b9ca0e52b832 339 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 199 318 1.3E-26 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain D521_0192 bbf06f5f883801d6bc90b9ca0e52b832 339 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 173 2.0E-24 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain D521_0192 bbf06f5f883801d6bc90b9ca0e52b832 339 SUPERFAMILY SSF51735 1 146 2.45E-21 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0192 bbf06f5f883801d6bc90b9ca0e52b832 339 Gene3D G3DSA:3.40.50.720 1 196 1.1E-62 T 14-10-2018 D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 Gene3D G3DSA:3.40.50.300 1 233 1.7E-50 T 14-10-2018 D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 Pfam PF06470 SMC proteins Flexible Hinge Domain 523 625 1.1E-7 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1165 21.767 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1163 0.0 T 14-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 SUPERFAMILY SSF57997 265 497 1.11E-7 T 14-10-2018 D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 SUPERFAMILY SSF52540 3 1163 1.04E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 SMART SM00968 518 627 6.4E-6 T 14-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1156 3.2E-61 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 SUPERFAMILY SSF75553 477 675 2.62E-11 T 14-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 Gene3D G3DSA:3.40.50.300 1012 1173 1.4E-45 T 14-10-2018 D521_1267 56fcdce79e938a32ff566cd3b5b8831b 1173 PIRSF PIRSF005719 1 1171 2.7E-252 T 14-10-2018 IPR024704 Structural maintenance of chromosomes protein D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 SMART SM01086 344 438 3.0E-34 T 14-10-2018 IPR019489 Clp ATPase, C-terminal D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 Pfam PF07724 AAA domain (Cdc48 subfamily) 141 337 1.4E-49 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 SUPERFAMILY SSF57716 14 49 1.71E-11 T 14-10-2018 D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 4 442 52.687 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 344 421 5.9E-15 T 14-10-2018 IPR019489 Clp ATPase, C-terminal D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 Pfam PF06689 ClpX C4-type zinc finger 14 51 2.8E-19 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 SMART SM00994 13 52 2.1E-23 T 14-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 SUPERFAMILY SSF52540 63 427 2.51E-73 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 Gene3D G3DSA:3.30.50.30 4 53 6.5E-24 T 14-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 Gene3D G3DSA:1.10.8.60 343 451 5.5E-37 T 14-10-2018 D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 11 438 5.8E-201 T 14-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 SMART SM00382 140 293 9.6E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0931 3dfcfd9684b8d762a7a970bdfa9b40bd 453 Gene3D G3DSA:3.40.50.300 59 342 5.4E-110 T 14-10-2018 D521_0995 cb9ee8a8735f81ab01069844af357c17 411 Gene3D G3DSA:3.40.1190.10 1 267 6.0E-79 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0995 cb9ee8a8735f81ab01069844af357c17 411 SUPERFAMILY SSF53623 1 264 2.49E-79 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0995 cb9ee8a8735f81ab01069844af357c17 411 Pfam PF02875 Mur ligase family, glutamate ligase domain 267 319 2.0E-5 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 D521_0995 cb9ee8a8735f81ab01069844af357c17 411 SUPERFAMILY SSF53244 266 405 2.2E-30 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0995 cb9ee8a8735f81ab01069844af357c17 411 PIRSF PIRSF001563 1 411 6.3E-98 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 D521_0995 cb9ee8a8735f81ab01069844af357c17 411 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 22 45 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 D521_0995 cb9ee8a8735f81ab01069844af357c17 411 TIGRFAM TIGR01499 folC: bifunctional protein FolC 3 405 1.3E-94 T 14-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 D521_0995 cb9ee8a8735f81ab01069844af357c17 411 Pfam PF08245 Mur ligase middle domain 24 167 1.1E-10 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 D521_0995 cb9ee8a8735f81ab01069844af357c17 411 Gene3D G3DSA:3.90.190.20 268 410 2.9E-32 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0357 e36d36d960b6ca98f86d3dc362e8df21 105 SMART SM00418 22 99 4.1E-20 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0357 e36d36d960b6ca98f86d3dc362e8df21 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 7.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0357 e36d36d960b6ca98f86d3dc362e8df21 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 7.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0357 e36d36d960b6ca98f86d3dc362e8df21 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 54 7.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0357 e36d36d960b6ca98f86d3dc362e8df21 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 7.7E-12 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0357 e36d36d960b6ca98f86d3dc362e8df21 105 SUPERFAMILY SSF46785 17 103 1.55E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0357 e36d36d960b6ca98f86d3dc362e8df21 105 Pfam PF01022 Bacterial regulatory protein, arsR family 33 74 2.4E-9 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0357 e36d36d960b6ca98f86d3dc362e8df21 105 Gene3D G3DSA:1.10.10.10 9 105 6.1E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1065 ac98b04391db15f2b8742310e0e329e9 737 Gene3D G3DSA:1.20.1220.12 597 737 7.4E-69 T 14-10-2018 D521_1065 ac98b04391db15f2b8742310e0e329e9 737 Gene3D G3DSA:2.170.170.11 135 264 8.5E-267 T 14-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 D521_1065 ac98b04391db15f2b8742310e0e329e9 737 Hamap MF_00641 Malate synthase G [glcB]. 1 737 376.238 T 14-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 D521_1065 ac98b04391db15f2b8742310e0e329e9 737 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 6 734 0.0 T 14-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 D521_1065 ac98b04391db15f2b8742310e0e329e9 737 SUPERFAMILY SSF51645 3 734 7.98E-287 T 14-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 D521_1065 ac98b04391db15f2b8742310e0e329e9 737 Pfam PF01274 Malate synthase 18 710 3.7E-161 T 14-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 D521_1065 ac98b04391db15f2b8742310e0e329e9 737 Gene3D G3DSA:3.20.20.360 10 595 8.5E-267 T 14-10-2018 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 171 319 4.3E-50 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 24 322 75.239 T 14-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 25 165 1.3E-48 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 25 321 4.5E-109 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 Gene3D G3DSA:3.40.50.1370 26 318 1.3E-113 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 70 77 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 Gene3D G3DSA:3.40.50.1370 155 308 1.3E-113 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 274 283 1.9E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 70 89 1.9E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 152 163 1.9E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 286 309 1.9E-27 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 SUPERFAMILY SSF53671 24 321 9.04E-103 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 PRINTS PR00102 Ornithine carbamoyltransferase signature 101 114 2.2E-28 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 PRINTS PR00102 Ornithine carbamoyltransferase signature 68 82 2.2E-28 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 PRINTS PR00102 Ornithine carbamoyltransferase signature 141 155 2.2E-28 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 PRINTS PR00102 Ornithine carbamoyltransferase signature 238 248 2.2E-28 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 D521_1736 aa6291de40a2206bd0dae752e9cd381c 326 PRINTS PR00102 Ornithine carbamoyltransferase signature 300 311 2.2E-28 T 14-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 SUPERFAMILY SSF52374 5 397 2.15E-90 T 14-10-2018 D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 Pfam PF00579 tRNA synthetases class I (W and Y) 244 348 5.1E-10 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 Pfam PF00579 tRNA synthetases class I (W and Y) 5 170 2.2E-49 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 Gene3D G3DSA:1.10.240.10 260 365 8.3E-37 T 14-10-2018 D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 3 398 35.104 T 14-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 Gene3D G3DSA:3.40.50.620 1 229 5.7E-76 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 67 86 1.5E-23 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 16 32 1.5E-23 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 145 166 1.5E-23 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 177 5.8E-59 T 14-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 D521_0851 fd97c5432fcec1062cdc60346b19d36c 400 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 12 21 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0678 ddba698fc6ed58daf5dc262e5b43b04f 261 SUPERFAMILY SSF46626 29 149 2.7E-27 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0678 ddba698fc6ed58daf5dc262e5b43b04f 261 PIRSF PIRSF038455 10 261 1.0E-80 T 14-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 D521_0678 ddba698fc6ed58daf5dc262e5b43b04f 261 Gene3D G3DSA:1.10.760.10 57 142 1.2E-90 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0678 ddba698fc6ed58daf5dc262e5b43b04f 261 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 55 260 4.0E-69 T 14-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 D521_0678 ddba698fc6ed58daf5dc262e5b43b04f 261 SUPERFAMILY SSF46626 153 261 2.26E-28 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0678 ddba698fc6ed58daf5dc262e5b43b04f 261 Gene3D G3DSA:1.10.760.10 31 260 1.2E-90 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1478 1c237848fd8856408e8c337d322d7f98 220 Gene3D G3DSA:3.40.50.300 2 220 9.9E-70 T 14-10-2018 D521_1478 1c237848fd8856408e8c337d322d7f98 220 Hamap MF_00238 Cytidylate kinase [cmk]. 5 219 31.226 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 D521_1478 1c237848fd8856408e8c337d322d7f98 220 SUPERFAMILY SSF52540 5 216 2.18E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1478 1c237848fd8856408e8c337d322d7f98 220 Pfam PF02224 Cytidylate kinase 7 215 2.9E-65 T 14-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 D521_1478 1c237848fd8856408e8c337d322d7f98 220 TIGRFAM TIGR00017 cmk: cytidylate kinase 5 213 5.8E-66 T 14-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 D521_1402 a8648ff5704161753b1e5033629f90e3 124 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.406 T 14-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 D521_1402 a8648ff5704161753b1e5033629f90e3 124 Pfam PF01250 Ribosomal protein S6 3 91 6.0E-27 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1402 a8648ff5704161753b1e5033629f90e3 124 SUPERFAMILY SSF54995 1 104 5.1E-37 T 14-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1402 a8648ff5704161753b1e5033629f90e3 124 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 6.9E-33 T 14-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1402 a8648ff5704161753b1e5033629f90e3 124 Gene3D G3DSA:3.30.70.60 1 92 7.5E-32 T 14-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 D521_0139 64b62272ad5ebe015974340576968bcb 256 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 64 73 - T 14-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 D521_0139 64b62272ad5ebe015974340576968bcb 256 SMART SM00987 56 230 1.4E-14 T 14-10-2018 D521_0139 64b62272ad5ebe015974340576968bcb 256 Gene3D G3DSA:3.40.470.10 1 247 4.1E-68 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 D521_0139 64b62272ad5ebe015974340576968bcb 256 SUPERFAMILY SSF52141 9 241 1.26E-61 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 D521_0139 64b62272ad5ebe015974340576968bcb 256 SMART SM00986 56 230 1.4E-14 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 D521_0139 64b62272ad5ebe015974340576968bcb 256 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 11 233 1.4E-55 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 D521_0139 64b62272ad5ebe015974340576968bcb 256 Pfam PF03167 Uracil DNA glycosylase superfamily 61 229 5.2E-17 T 14-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 D521_0139 64b62272ad5ebe015974340576968bcb 256 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 10 241 33.107 T 14-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 D521_1434 d8cd134fe2457009db0ec620f759aa7a 257 Gene3D G3DSA:3.40.1010.10 5 138 7.1E-32 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 D521_1434 d8cd134fe2457009db0ec620f759aa7a 257 Gene3D G3DSA:3.30.950.10 139 257 2.6E-39 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 D521_1434 d8cd134fe2457009db0ec620f759aa7a 257 SUPERFAMILY SSF53790 6 239 1.44E-51 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 304 311 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1060 0.0 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Gene3D G3DSA:3.30.470.20 670 944 1.3E-118 T 14-10-2018 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 847 854 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Pfam PF02142 MGS-like domain 965 1051 2.9E-19 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Gene3D G3DSA:3.30.470.20 119 409 1.3E-127 T 14-10-2018 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1079 13.419 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 714 728 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 SUPERFAMILY SSF56059 678 942 2.65E-104 T 14-10-2018 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 549 6.6E-40 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 SUPERFAMILY SSF48108 403 554 1.27E-52 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 171 185 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 SMART SM01096 426 549 8.6E-74 T 14-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 SUPERFAMILY SSF56059 128 408 8.84E-107 T 14-10-2018 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Gene3D G3DSA:1.10.1030.10 410 555 9.1E-47 T 14-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 SMART SM00851 964 1051 4.1E-29 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Gene3D G3DSA:3.40.50.20 559 667 8.6E-49 T 14-10-2018 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Gene3D G3DSA:3.40.50.1380 945 1087 3.5E-34 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 SUPERFAMILY SSF52335 944 1085 1.09E-35 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 3.5E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 387 405 3.5E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 175 187 3.5E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 211 230 3.5E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 3.5E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 304 333 3.5E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 246 263 3.5E-66 T 14-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1072 13.186 T 14-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 SUPERFAMILY SSF52440 1 127 4.6E-51 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 SUPERFAMILY SSF52440 563 680 1.73E-49 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Gene3D G3DSA:3.40.50.20 1 116 1.2E-49 T 14-10-2018 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 678 884 1.2E-36 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0779 28f33f5ae62b4450ac093ebb0330a283 1087 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 341 1.1E-69 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_1477 c3535b67c399788c09823f03f580819a 557 Gene3D G3DSA:2.40.50.140 445 527 2.6E-19 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 SUPERFAMILY SSF50249 255 356 7.86E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1477 c3535b67c399788c09823f03f580819a 557 PIRSF PIRSF002111 1 534 2.1E-209 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 D521_1477 c3535b67c399788c09823f03f580819a 557 Gene3D G3DSA:2.40.50.140 6 97 6.0E-14 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 SMART SM00316 362 434 1.1E-22 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_1477 c3535b67c399788c09823f03f580819a 557 SMART SM00316 190 260 5.0E-29 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_1477 c3535b67c399788c09823f03f580819a 557 SMART SM00316 275 347 5.8E-21 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_1477 c3535b67c399788c09823f03f580819a 557 SMART SM00316 449 520 2.9E-19 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_1477 c3535b67c399788c09823f03f580819a 557 SMART SM00316 103 171 1.3E-9 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_1477 c3535b67c399788c09823f03f580819a 557 SMART SM00316 19 87 0.0065 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_1477 c3535b67c399788c09823f03f580819a 557 Pfam PF00575 S1 RNA binding domain 190 260 8.4E-22 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_1477 c3535b67c399788c09823f03f580819a 557 Pfam PF00575 S1 RNA binding domain 19 85 1.5E-6 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_1477 c3535b67c399788c09823f03f580819a 557 Pfam PF00575 S1 RNA binding domain 362 434 1.1E-18 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_1477 c3535b67c399788c09823f03f580819a 557 Pfam PF00575 S1 RNA binding domain 450 520 2.7E-12 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_1477 c3535b67c399788c09823f03f580819a 557 Pfam PF00575 S1 RNA binding domain 277 347 2.6E-17 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_1477 c3535b67c399788c09823f03f580819a 557 Pfam PF00575 S1 RNA binding domain 103 171 2.0E-12 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_1477 c3535b67c399788c09823f03f580819a 557 SUPERFAMILY SSF50249 342 440 1.79E-22 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1477 c3535b67c399788c09823f03f580819a 557 SUPERFAMILY SSF50249 429 529 1.65E-20 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1477 c3535b67c399788c09823f03f580819a 557 Gene3D G3DSA:2.40.50.140 98 181 2.3E-9 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 Gene3D G3DSA:2.40.50.140 268 357 2.6E-25 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 Gene3D G3DSA:2.40.50.140 358 444 1.5E-23 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 SUPERFAMILY SSF50249 189 275 7.55E-26 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1477 c3535b67c399788c09823f03f580819a 557 Gene3D G3DSA:2.40.50.140 187 267 1.0E-27 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 SUPERFAMILY SSF50249 1 113 3.58E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1477 c3535b67c399788c09823f03f580819a 557 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 8.1E-203 T 14-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 D521_1477 c3535b67c399788c09823f03f580819a 557 SUPERFAMILY SSF50249 104 184 2.69E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1477 c3535b67c399788c09823f03f580819a 557 PRINTS PR00681 Ribosomal protein S1 signature 21 39 3.7E-81 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 PRINTS PR00681 Ribosomal protein S1 signature 126 143 3.7E-81 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 PRINTS PR00681 Ribosomal protein S1 signature 39 53 3.7E-81 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 PRINTS PR00681 Ribosomal protein S1 signature 330 348 3.7E-81 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 PRINTS PR00681 Ribosomal protein S1 signature 108 124 3.7E-81 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 PRINTS PR00681 Ribosomal protein S1 signature 212 233 3.7E-81 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 PRINTS PR00681 Ribosomal protein S1 signature 155 175 3.7E-81 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 PRINTS PR00681 Ribosomal protein S1 signature 290 309 3.7E-81 T 14-10-2018 D521_1477 c3535b67c399788c09823f03f580819a 557 PRINTS PR00681 Ribosomal protein S1 signature 84 103 3.7E-81 T 14-10-2018 D521_0334 f335cf3575a33fc13625c6910b76e551 575 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 119 275 3.0E-32 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 D521_0334 f335cf3575a33fc13625c6910b76e551 575 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 50 110 2.5E-19 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 D521_0334 f335cf3575a33fc13625c6910b76e551 575 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 347 413 1.8E-14 T 14-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 D521_0334 f335cf3575a33fc13625c6910b76e551 575 Gene3D G3DSA:3.30.413.10 423 573 9.8E-32 T 14-10-2018 D521_0334 f335cf3575a33fc13625c6910b76e551 575 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 426 564 1.2E-9 T 14-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 D521_0334 f335cf3575a33fc13625c6910b76e551 575 SUPERFAMILY SSF55124 255 436 1.32E-24 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 D521_0334 f335cf3575a33fc13625c6910b76e551 575 SUPERFAMILY SSF56014 120 278 3.93E-39 T 14-10-2018 D521_0334 f335cf3575a33fc13625c6910b76e551 575 SUPERFAMILY SSF56014 423 565 3.27E-39 T 14-10-2018 D521_0334 f335cf3575a33fc13625c6910b76e551 575 SUPERFAMILY SSF55124 1 126 1.45E-34 T 14-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 D521_0334 f335cf3575a33fc13625c6910b76e551 575 PRINTS PR00397 Sirohaem Fe-binding site signature 425 443 6.3E-5 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 D521_0334 f335cf3575a33fc13625c6910b76e551 575 PRINTS PR00397 Sirohaem Fe-binding site signature 471 489 6.3E-5 T 14-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 D521_1036 0000ec61924cfa22c5c3b0c59246060b 898 SUPERFAMILY SSF52922 707 897 9.94E-54 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 D521_1036 0000ec61924cfa22c5c3b0c59246060b 898 Gene3D G3DSA:3.40.50.920 712 898 2.0E-70 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 D521_1036 0000ec61924cfa22c5c3b0c59246060b 898 Gene3D G3DSA:3.40.50.970 477 711 8.3E-107 T 14-10-2018 D521_1036 0000ec61924cfa22c5c3b0c59246060b 898 PIRSF PIRSF000156 6 898 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 D521_1036 0000ec61924cfa22c5c3b0c59246060b 898 Gene3D G3DSA:3.40.50.970 64 476 1.9E-127 T 14-10-2018 D521_1036 0000ec61924cfa22c5c3b0c59246060b 898 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 14 897 0.0 T 14-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 D521_1036 0000ec61924cfa22c5c3b0c59246060b 898 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 91 300 1.4E-8 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 D521_1036 0000ec61924cfa22c5c3b0c59246060b 898 SUPERFAMILY SSF52518 65 471 2.17E-133 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_1036 0000ec61924cfa22c5c3b0c59246060b 898 SUPERFAMILY SSF52518 478 706 1.43E-96 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_1633 5c86c7b10843ecf7d9d3830af581db31 627 SMART SM00387 515 624 6.7E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_1633 5c86c7b10843ecf7d9d3830af581db31 627 SMART SM00388 416 475 1.9E-8 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_1633 5c86c7b10843ecf7d9d3830af581db31 627 Pfam PF07696 7TMR-DISM extracellular 2 30 155 4.8E-12 T 14-10-2018 IPR011622 7TM-DISM receptor, extracellular domain, type 2 D521_1633 5c86c7b10843ecf7d9d3830af581db31 627 Gene3D G3DSA:1.10.287.130 402 471 7.0E-7 T 14-10-2018 D521_1633 5c86c7b10843ecf7d9d3830af581db31 627 Gene3D G3DSA:2.60.40.2380 27 163 7.0E-9 T 14-10-2018 D521_1633 5c86c7b10843ecf7d9d3830af581db31 627 Gene3D G3DSA:3.30.565.10 501 626 1.1E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1633 5c86c7b10843ecf7d9d3830af581db31 627 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 516 612 1.6E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_1633 5c86c7b10843ecf7d9d3830af581db31 627 SUPERFAMILY SSF47384 416 476 1.1E-6 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 D521_1633 5c86c7b10843ecf7d9d3830af581db31 627 Pfam PF00512 His Kinase A (phospho-acceptor) domain 418 474 3.8E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_1633 5c86c7b10843ecf7d9d3830af581db31 627 SUPERFAMILY SSF55874 465 622 3.27E-20 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0050 e6dea173c7766717cf1bd79e58011db3 396 Pfam PF03144 Elongation factor Tu domain 2 227 295 3.6E-16 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 Gene3D G3DSA:3.40.50.300 1 205 2.9E-70 T 14-10-2018 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 5.9E-59 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 SUPERFAMILY SSF50447 207 303 7.86E-30 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily D521_0050 e6dea173c7766717cf1bd79e58011db3 396 SUPERFAMILY SSF52540 6 221 3.72E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0050 e6dea173c7766717cf1bd79e58011db3 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 7.6E-25 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 2.3E-15 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site D521_0050 e6dea173c7766717cf1bd79e58011db3 396 Gene3D G3DSA:2.40.30.10 208 336 6.4E-52 T 14-10-2018 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 1.8E-228 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 Gene3D G3DSA:2.40.30.10 340 395 1.3E-29 T 14-10-2018 D521_0050 e6dea173c7766717cf1bd79e58011db3 396 SUPERFAMILY SSF50465 304 396 9.5E-37 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal D521_0050 e6dea173c7766717cf1bd79e58011db3 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 1.1E-33 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal D521_0050 e6dea173c7766717cf1bd79e58011db3 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.188 T 14-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 D521_1902 0b17b7949f2cfbc18a28cd62e7de1eb3 659 SUPERFAMILY SSF51735 410 550 1.29E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1902 0b17b7949f2cfbc18a28cd62e7de1eb3 659 Gene3D G3DSA:3.30.70.1450 582 658 6.9E-9 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 D521_1902 0b17b7949f2cfbc18a28cd62e7de1eb3 659 TIGRFAM TIGR00932 2a37: transporter, monovalent cation:proton antiporter-2 (CPA2) family 14 287 1.4E-71 T 14-10-2018 IPR004771 K+/H+ exchanger GO:0006812|GO:0008324|GO:0016021 D521_1902 0b17b7949f2cfbc18a28cd62e7de1eb3 659 SUPERFAMILY SSF116726 572 655 1.83E-10 T 14-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 D521_1902 0b17b7949f2cfbc18a28cd62e7de1eb3 659 Pfam PF02254 TrkA-N domain 413 526 9.1E-25 T 14-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 D521_1902 0b17b7949f2cfbc18a28cd62e7de1eb3 659 Pfam PF02080 TrkA-C domain 586 658 1.7E-9 T 14-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 D521_1902 0b17b7949f2cfbc18a28cd62e7de1eb3 659 Gene3D G3DSA:1.20.1530.20 2 386 2.0E-85 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily D521_1902 0b17b7949f2cfbc18a28cd62e7de1eb3 659 Gene3D G3DSA:3.40.50.720 408 569 4.5E-37 T 14-10-2018 D521_1902 0b17b7949f2cfbc18a28cd62e7de1eb3 659 Pfam PF00999 Sodium/hydrogen exchanger family 9 377 1.4E-66 T 14-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 D521_1556 bf99ff4e0bfe8765bd0ffde08dd7005c 126 Gene3D G3DSA:3.30.56.110 4 126 7.9E-52 T 14-10-2018 D521_1556 bf99ff4e0bfe8765bd0ffde08dd7005c 126 Pfam PF09996 Uncharacterized protein conserved in bacteria (DUF2237) 8 121 3.8E-52 T 14-10-2018 IPR018714 Protein of unknown function DUF2237 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 47 60 6.2E-36 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 6.2E-36 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 33 46 6.2E-36 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 139 155 6.2E-36 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 177 6.2E-36 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 184 197 6.2E-36 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 6.2E-36 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 Gene3D G3DSA:3.40.50.1000 9 210 1.8E-63 T 14-10-2018 IPR023214 HAD superfamily D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 7 200 5.7E-61 T 14-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 9 188 6.0E-26 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 Pfam PF13419 Haloacid dehalogenase-like hydrolase 95 195 3.4E-15 T 14-10-2018 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 Gene3D G3DSA:1.10.150.240 21 95 1.8E-63 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 D521_1685 c5405e43d8a4700310b60f38cd4fbf17 224 SUPERFAMILY SSF56784 7 223 1.67E-46 T 14-10-2018 IPR036412 HAD-like superfamily D521_1728 cba46541ac3fc390c510d81310c356fd 149 SUPERFAMILY SSF51283 16 148 8.24E-50 T 14-10-2018 IPR036157 dUTPase-like superfamily D521_1728 cba46541ac3fc390c510d81310c356fd 149 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 6 148 32.705 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 D521_1728 cba46541ac3fc390c510d81310c356fd 149 TIGRFAM TIGR00576 dut: dUTP diphosphatase 8 148 7.6E-48 T 14-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 D521_1728 cba46541ac3fc390c510d81310c356fd 149 Gene3D G3DSA:2.70.40.10 1 148 5.8E-52 T 14-10-2018 IPR036157 dUTPase-like superfamily D521_1728 cba46541ac3fc390c510d81310c356fd 149 Pfam PF00692 dUTPase 16 147 1.3E-37 T 14-10-2018 IPR029054 dUTPase-like D521_0932 7284c2dfbd117102582f641efb39a794 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 354 490 7.7E-16 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 D521_0932 7284c2dfbd117102582f641efb39a794 810 Gene3D G3DSA:3.40.50.300 316 492 7.2E-61 T 14-10-2018 D521_0932 7284c2dfbd117102582f641efb39a794 810 Gene3D G3DSA:1.20.58.1480 123 248 6.6E-44 T 14-10-2018 D521_0932 7284c2dfbd117102582f641efb39a794 810 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 572 774 2.5E-92 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 D521_0932 7284c2dfbd117102582f641efb39a794 810 Hamap MF_01973 Lon protease [lon]. 14 774 69.855 T 14-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 D521_0932 7284c2dfbd117102582f641efb39a794 810 SMART SM00464 13 205 5.6E-71 T 14-10-2018 IPR003111 Lon, substrate-binding domain D521_0932 7284c2dfbd117102582f641efb39a794 810 SUPERFAMILY SSF52540 314 588 5.4E-48 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0932 7284c2dfbd117102582f641efb39a794 810 Gene3D G3DSA:1.10.8.60 493 586 1.1E-30 T 14-10-2018 D521_0932 7284c2dfbd117102582f641efb39a794 810 Gene3D G3DSA:3.30.230.10 587 774 1.0E-79 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup D521_0932 7284c2dfbd117102582f641efb39a794 810 TIGRFAM TIGR00763 lon: endopeptidase La 15 773 2.5E-293 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 D521_0932 7284c2dfbd117102582f641efb39a794 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 358 377 1.2E-54 T 14-10-2018 D521_0932 7284c2dfbd117102582f641efb39a794 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 675 694 1.2E-54 T 14-10-2018 D521_0932 7284c2dfbd117102582f641efb39a794 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 728 746 1.2E-54 T 14-10-2018 D521_0932 7284c2dfbd117102582f641efb39a794 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 597 613 1.2E-54 T 14-10-2018 D521_0932 7284c2dfbd117102582f641efb39a794 810 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 705 724 1.2E-54 T 14-10-2018 D521_0932 7284c2dfbd117102582f641efb39a794 810 SUPERFAMILY SSF88697 13 204 3.23E-52 T 14-10-2018 IPR015947 PUA-like superfamily D521_0932 7284c2dfbd117102582f641efb39a794 810 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 14 200 1.9E-43 T 14-10-2018 IPR003111 Lon, substrate-binding domain D521_0932 7284c2dfbd117102582f641efb39a794 810 PIRSF PIRSF001174 6 777 0.0 T 14-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 D521_0932 7284c2dfbd117102582f641efb39a794 810 Gene3D G3DSA:2.30.130.40 7 119 1.8E-36 T 14-10-2018 D521_0932 7284c2dfbd117102582f641efb39a794 810 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 678 686 - T 14-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 D521_0932 7284c2dfbd117102582f641efb39a794 810 SMART SM00382 350 494 1.3E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0932 7284c2dfbd117102582f641efb39a794 810 SUPERFAMILY SSF54211 597 772 3.15E-58 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_1117 10ad987cea6950837790ca779293cdc7 332 PIRSF PIRSF017082 1 331 1.8E-76 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1117 10ad987cea6950837790ca779293cdc7 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 55 328 4.2E-85 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1117 10ad987cea6950837790ca779293cdc7 332 Gene3D G3DSA:3.40.190.150 36 322 4.5E-107 T 14-10-2018 D521_1117 10ad987cea6950837790ca779293cdc7 332 Gene3D G3DSA:3.40.190.10 134 257 4.5E-107 T 14-10-2018 D521_1117 10ad987cea6950837790ca779293cdc7 332 SUPERFAMILY SSF53850 124 291 3.12E-10 T 14-10-2018 D521_0493 201ef3db81731b3ad5835a8f8f5b8b11 154 Gene3D G3DSA:3.40.50.10110 1 150 5.2E-29 T 14-10-2018 IPR036768 DNA polymerase III subunit chi superfamily D521_0493 201ef3db81731b3ad5835a8f8f5b8b11 154 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 147 1.8E-33 T 14-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 D521_0493 201ef3db81731b3ad5835a8f8f5b8b11 154 SUPERFAMILY SSF102400 1 151 1.44E-29 T 14-10-2018 IPR036768 DNA polymerase III subunit chi superfamily D521_1429 ee3b2308851f8cdd6184a460450ad576 328 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 239 328 5.8E-35 T 14-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 D521_1429 ee3b2308851f8cdd6184a460450ad576 328 Gene3D G3DSA:3.40.47.10 1 328 7.4E-127 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 D521_1429 ee3b2308851f8cdd6184a460450ad576 328 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 193 4.1E-33 T 14-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 D521_1429 ee3b2308851f8cdd6184a460450ad576 328 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 3 328 68.781 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 D521_1429 ee3b2308851f8cdd6184a460450ad576 328 SUPERFAMILY SSF53901 4 328 2.2E-69 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 D521_1429 ee3b2308851f8cdd6184a460450ad576 328 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 327 2.5E-123 T 14-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 D521_1023 c446276f8a7e37ea6353fcd43af9e5ce 213 Pfam PF01323 DSBA-like thioredoxin domain 15 188 1.5E-22 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 D521_1023 c446276f8a7e37ea6353fcd43af9e5ce 213 Gene3D G3DSA:3.40.30.10 14 200 6.2E-41 T 14-10-2018 D521_1023 c446276f8a7e37ea6353fcd43af9e5ce 213 PIRSF PIRSF006386 8 202 8.2E-31 T 14-10-2018 IPR014440 HCCA isomerase/glutathione S-transferase kappa Reactome: R-HSA-156590|Reactome: R-HSA-9033241 D521_1023 c446276f8a7e37ea6353fcd43af9e5ce 213 SUPERFAMILY SSF52833 14 194 1.49E-29 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1002 b2b2d5578301590d8db5a55af01deff5 385 Gene3D G3DSA:3.40.50.720 9 372 1.8E-137 T 14-10-2018 D521_1002 b2b2d5578301590d8db5a55af01deff5 385 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 6 383 32.486 T 14-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 D521_1002 b2b2d5578301590d8db5a55af01deff5 385 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 132 1.7E-26 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 D521_1002 b2b2d5578301590d8db5a55af01deff5 385 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 369 2.1E-49 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 D521_1002 b2b2d5578301590d8db5a55af01deff5 385 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 277 291 - T 14-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 D521_1002 b2b2d5578301590d8db5a55af01deff5 385 SUPERFAMILY SSF51735 9 157 3.1E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1002 b2b2d5578301590d8db5a55af01deff5 385 Gene3D G3DSA:3.30.360.10 145 366 1.8E-137 T 14-10-2018 D521_1002 b2b2d5578301590d8db5a55af01deff5 385 PIRSF PIRSF000148 6 385 3.2E-62 T 14-10-2018 D521_1002 b2b2d5578301590d8db5a55af01deff5 385 SMART SM00859 8 132 1.2E-26 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 D521_1002 b2b2d5578301590d8db5a55af01deff5 385 SUPERFAMILY SSF55347 144 370 1.39E-72 T 14-10-2018 D521_1002 b2b2d5578301590d8db5a55af01deff5 385 TIGRFAM TIGR01745 asd_gamma: aspartate-semialdehyde dehydrogenase 9 383 6.5E-180 T 14-10-2018 IPR011534 Aspartate-semialdehyde dehydrogenase, gamma-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 D521_0403 72b81508ddbd35cddbe13cee49cc6f66 460 Pfam PF02321 Outer membrane efflux protein 31 233 8.9E-20 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_0403 72b81508ddbd35cddbe13cee49cc6f66 460 Pfam PF02321 Outer membrane efflux protein 263 445 1.7E-21 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_0403 72b81508ddbd35cddbe13cee49cc6f66 460 Gene3D G3DSA:1.20.1600.10 27 460 3.2E-73 T 14-10-2018 D521_0403 72b81508ddbd35cddbe13cee49cc6f66 460 SUPERFAMILY SSF56954 9 448 2.09E-60 T 14-10-2018 D521_1024 6fd4aee981ebdf838b17cf65fdea6588 191 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 60 77 - T 14-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 D521_1024 6fd4aee981ebdf838b17cf65fdea6588 191 SUPERFAMILY SSF50891 23 190 2.63E-51 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily D521_1024 6fd4aee981ebdf838b17cf65fdea6588 191 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 26 188 8.5E-43 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 D521_1024 6fd4aee981ebdf838b17cf65fdea6588 191 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 140 155 6.1E-10 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 D521_1024 6fd4aee981ebdf838b17cf65fdea6588 191 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 39 54 6.1E-10 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 D521_1024 6fd4aee981ebdf838b17cf65fdea6588 191 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 65 77 6.1E-10 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 D521_1024 6fd4aee981ebdf838b17cf65fdea6588 191 PIRSF PIRSF001467 6 186 2.9E-24 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 D521_1024 6fd4aee981ebdf838b17cf65fdea6588 191 Gene3D G3DSA:2.40.100.10 22 190 2.7E-58 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 Pfam PF02310 B12 binding domain 432 526 1.5E-18 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 Gene3D G3DSA:1.10.288.10 624 785 7.1E-130 T 14-10-2018 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 Gene3D G3DSA:3.10.196.10 591 911 7.1E-130 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 SUPERFAMILY SSF51717 27 297 1.03E-89 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 Pfam PF02607 B12 binding domain 332 409 1.9E-25 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 PIRSF PIRSF000381 1 887 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 TIGRFAM TIGR02082 metH: methionine synthase 6 884 0.0 T 14-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 SUPERFAMILY SSF52242 426 582 9.16E-44 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 Gene3D G3DSA:3.40.50.280 427 583 2.1E-55 T 14-10-2018 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 SUPERFAMILY SSF47644 326 416 1.44E-26 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 SMART SM01018 330 417 1.3E-42 T 14-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 Gene3D G3DSA:1.10.1240.10 322 414 3.5E-37 T 14-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 Gene3D G3DSA:3.20.20.20 11 318 7.7E-130 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 SUPERFAMILY SSF56507 590 914 1.57E-121 T 14-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 Pfam PF00809 Pterin binding enzyme 31 269 7.5E-59 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1977 8f868c990af2d4a9cca443c5dca08e6a 915 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 626 900 2.0E-117 T 14-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 Gene3D G3DSA:3.40.50.300 438 681 5.3E-54 T 14-10-2018 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 Pfam PF00005 ABC transporter 1215 1360 4.9E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 SUPERFAMILY SSF90123 134 419 4.32E-46 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 Pfam PF00005 ABC transporter 472 620 2.2E-26 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 Gene3D G3DSA:3.90.70.10 741 844 2.4E-5 T 14-10-2018 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 Gene3D G3DSA:3.40.50.300 1187 1425 4.9E-68 T 14-10-2018 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 Pfam PF00664 ABC transporter transmembrane region 134 393 1.4E-24 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 Pfam PF00664 ABC transporter transmembrane region 883 1143 2.7E-18 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 SUPERFAMILY SSF52540 450 668 1.91E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 SMART SM00382 1222 1409 2.1E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 SMART SM00382 480 665 3.2E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 SUPERFAMILY SSF90123 868 1174 1.06E-40 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 SUPERFAMILY SSF52540 1189 1421 5.33E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 Gene3D G3DSA:1.20.1560.10 118 425 9.6E-46 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 D521_0653 3fd1fee5ac3556d245e87ace61d29ef1 1425 Gene3D G3DSA:1.20.1560.10 870 1180 1.9E-39 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 D521_0634 95336eac00c42a852bbf10467a4499b0 410 SMART SM00471 229 364 1.0E-9 T 14-10-2018 IPR003607 HD/PDEase domain D521_0634 95336eac00c42a852bbf10467a4499b0 410 Pfam PF13185 GAF domain 42 186 1.7E-11 T 14-10-2018 IPR003018 GAF domain GO:0005515 D521_0634 95336eac00c42a852bbf10467a4499b0 410 Gene3D G3DSA:1.10.3210.10 208 398 4.2E-67 T 14-10-2018 D521_0634 95336eac00c42a852bbf10467a4499b0 410 TIGRFAM TIGR00277 HDIG: HDIG domain 233 323 2.6E-7 T 14-10-2018 IPR006675 HDIG domain D521_0634 95336eac00c42a852bbf10467a4499b0 410 SMART SM00065 26 198 5.6E-5 T 14-10-2018 IPR003018 GAF domain GO:0005515 D521_0634 95336eac00c42a852bbf10467a4499b0 410 SUPERFAMILY SSF55781 18 186 9.6E-20 T 14-10-2018 D521_0634 95336eac00c42a852bbf10467a4499b0 410 Gene3D G3DSA:3.30.450.40 16 204 7.6E-23 T 14-10-2018 IPR029016 GAF-like domain superfamily D521_0634 95336eac00c42a852bbf10467a4499b0 410 SUPERFAMILY SSF109604 225 394 4.04E-37 T 14-10-2018 D521_0634 95336eac00c42a852bbf10467a4499b0 410 Pfam PF13487 HD domain 286 346 7.9E-20 T 14-10-2018 D521_1775 1b1d2f23c78119b73a035bc5521a67e0 460 Gene3D G3DSA:3.40.50.11720 54 232 2.7E-42 T 14-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 D521_1775 1b1d2f23c78119b73a035bc5521a67e0 460 SUPERFAMILY SSF53756 79 453 3.77E-12 T 14-10-2018 D521_1775 1b1d2f23c78119b73a035bc5521a67e0 460 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 55 233 1.2E-52 T 14-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 D521_1775 1b1d2f23c78119b73a035bc5521a67e0 460 Gene3D G3DSA:3.40.50.2000 238 438 4.0E-56 T 14-10-2018 D521_0224 87b5eb4872a7479a21e6ba2835d5f28b 174 Gene3D G3DSA:3.90.950.20 1 170 1.8E-58 T 14-10-2018 IPR036653 CinA-like, C-terminal D521_0224 87b5eb4872a7479a21e6ba2835d5f28b 174 SUPERFAMILY SSF142433 8 169 2.35E-53 T 14-10-2018 IPR036653 CinA-like, C-terminal D521_0224 87b5eb4872a7479a21e6ba2835d5f28b 174 Pfam PF02464 Competence-damaged protein 9 169 2.5E-56 T 14-10-2018 IPR008136 CinA, C-terminal D521_0224 87b5eb4872a7479a21e6ba2835d5f28b 174 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 17 169 1.8E-43 T 14-10-2018 IPR008136 CinA, C-terminal D521_0492 37df0f215877fe3a12c5d8738b63f416 533 Gene3D G3DSA:3.40.220.10 21 219 6.4E-11 T 14-10-2018 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 Gene3D G3DSA:3.40.630.10 220 533 2.9E-137 T 14-10-2018 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 PRINTS PR00481 Cytosol aminopeptidase signature 301 318 1.4E-53 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 PRINTS PR00481 Cytosol aminopeptidase signature 410 425 1.4E-53 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 PRINTS PR00481 Cytosol aminopeptidase signature 323 344 1.4E-53 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 PRINTS PR00481 Cytosol aminopeptidase signature 382 402 1.4E-53 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 PRINTS PR00481 Cytosol aminopeptidase signature 360 381 1.4E-53 T 14-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 SUPERFAMILY SSF53187 219 531 5.96E-125 T 14-10-2018 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 224 526 1.1E-125 T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 21 533 34.555 T 14-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 SUPERFAMILY SSF52949 27 223 3.88E-9 T 14-10-2018 D521_0492 37df0f215877fe3a12c5d8738b63f416 533 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 386 393 - T 14-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 D521_2087 aed688b3621d13f0407dec59b04045e1 895 Gene3D G3DSA:3.40.50.300 274 450 3.7E-9 T 14-10-2018 D521_2087 aed688b3621d13f0407dec59b04045e1 895 SUPERFAMILY SSF52540 218 414 1.1E-6 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_2087 aed688b3621d13f0407dec59b04045e1 895 SMART SM00487 20 281 0.0036 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_2087 aed688b3621d13f0407dec59b04045e1 895 SUPERFAMILY SSF52540 3 259 6.95E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_2087 aed688b3621d13f0407dec59b04045e1 895 Pfam PF04851 Type III restriction enzyme, res subunit 3 256 4.4E-15 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 D521_1001 5538bbd5682f21acdf346b289104261b 461 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 148 222 1.4E-18 T 14-10-2018 IPR020012 Motility protein FimV, N-terminal D521_1001 5538bbd5682f21acdf346b289104261b 461 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 411 456 3.2E-8 T 14-10-2018 IPR020011 Motility protein FimV, C-terminal D521_1001 5538bbd5682f21acdf346b289104261b 461 Gene3D G3DSA:1.20.58.2200 398 456 6.2E-7 T 14-10-2018 IPR038440 FimV, C-terminal domain superfamily D521_1244 7cbd963d3c1065bf89db0122423f1a0e 400 Gene3D G3DSA:3.40.50.10540 8 394 8.0E-106 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_1244 7cbd963d3c1065bf89db0122423f1a0e 400 Pfam PF02515 CoA-transferase family III 8 377 2.3E-105 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 D521_1244 7cbd963d3c1065bf89db0122423f1a0e 400 Gene3D G3DSA:3.30.1540.10 236 328 8.0E-106 T 14-10-2018 D521_1244 7cbd963d3c1065bf89db0122423f1a0e 400 SUPERFAMILY SSF89796 6 400 3.4E-112 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_2004 a589e135b60222acb9a90c2ac73139ac 501 Gene3D G3DSA:3.40.50.720 257 419 1.2E-231 T 14-10-2018 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 SUPERFAMILY SSF52283 34 501 6.23E-109 T 14-10-2018 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 Gene3D G3DSA:3.40.50.1480 37 501 1.2E-231 T 14-10-2018 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 255 419 5.1E-76 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 SMART SM00996 34 500 0.0 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 106 120 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 30 493 46.887 T 14-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 SUPERFAMILY SSF51735 255 419 1.32E-73 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_2004 a589e135b60222acb9a90c2ac73139ac 501 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 277 293 - T 14-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 PIRSF PIRSF001109 21 501 3.2E-183 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 36 500 1.3E-141 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 SMART SM00997 255 419 1.1E-106 T 14-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 D521_2004 a589e135b60222acb9a90c2ac73139ac 501 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 37 493 2.1E-175 T 14-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 D521_0007 5073491cc3fc9669da6c186f6ea5febb 231 Gene3D G3DSA:3.40.50.300 1 231 2.3E-51 T 14-10-2018 D521_0007 5073491cc3fc9669da6c186f6ea5febb 231 SUPERFAMILY SSF52540 2 227 1.03E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0007 5073491cc3fc9669da6c186f6ea5febb 231 Pfam PF00005 ABC transporter 18 159 1.7E-23 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0007 5073491cc3fc9669da6c186f6ea5febb 231 SMART SM00382 27 208 1.9E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0007 5073491cc3fc9669da6c186f6ea5febb 231 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0170 ae0fa82a4f0b75a14e317b7a2d6485f7 357 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 6 143 3.2E-32 T 14-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0170 ae0fa82a4f0b75a14e317b7a2d6485f7 357 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 6 353 34.64 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0170 ae0fa82a4f0b75a14e317b7a2d6485f7 357 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 183 336 1.3E-36 T 14-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 D521_0170 ae0fa82a4f0b75a14e317b7a2d6485f7 357 SUPERFAMILY SSF53756 5 353 2.1E-116 T 14-10-2018 D521_0170 ae0fa82a4f0b75a14e317b7a2d6485f7 357 Gene3D G3DSA:3.40.50.2000 160 337 2.4E-111 T 14-10-2018 D521_0170 ae0fa82a4f0b75a14e317b7a2d6485f7 357 Gene3D G3DSA:3.40.50.2000 7 343 2.4E-111 T 14-10-2018 D521_0170 ae0fa82a4f0b75a14e317b7a2d6485f7 357 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 4 348 1.5E-99 T 14-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0857 0527b214caa82c580b144fc9b3f7c63c 202 Gene3D G3DSA:3.10.50.40 9 166 3.4E-42 T 14-10-2018 D521_0857 0527b214caa82c580b144fc9b3f7c63c 202 Gene3D G3DSA:2.40.10.330 76 135 3.4E-42 T 14-10-2018 D521_0857 0527b214caa82c580b144fc9b3f7c63c 202 SUPERFAMILY SSF54534 8 154 6.87E-24 T 14-10-2018 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 SMART SM01130 1 288 7.1E-131 T 14-10-2018 IPR002220 DapA-like GO:0016829 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 Gene3D G3DSA:3.20.20.70 1 290 1.9E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 2 286 1.1E-104 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 66 84 3.2E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 30 51 3.2E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 123 140 3.2E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 PRINTS PR00146 Dihydrodipicolinate synthase signature 98 114 3.2E-35 T 14-10-2018 IPR002220 DapA-like GO:0016829 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 SUPERFAMILY SSF51569 1 288 5.23E-97 T 14-10-2018 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 Pfam PF00701 Dihydrodipicolinate synthetase family 1 286 6.7E-93 T 14-10-2018 IPR002220 DapA-like GO:0016829 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 286 63.285 T 14-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 PIRSF PIRSF001365 1 290 7.4E-89 T 14-10-2018 IPR002220 DapA-like GO:0016829 D521_0853 5da0ae3c02c9ddf4e1a6885a8bd09b26 290 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 128 158 - T 14-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 D521_0986 848d4092b258f1c540ddf6b06a5a7466 113 Gene3D G3DSA:1.10.10.10 1 111 8.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0986 848d4092b258f1c540ddf6b06a5a7466 113 SMART SM00418 28 106 6.8E-18 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0986 848d4092b258f1c540ddf6b06a5a7466 113 SUPERFAMILY SSF46785 21 104 3.49E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0986 848d4092b258f1c540ddf6b06a5a7466 113 Pfam PF01022 Bacterial regulatory protein, arsR family 36 79 1.6E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0986 848d4092b258f1c540ddf6b06a5a7466 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 30 45 3.2E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0986 848d4092b258f1c540ddf6b06a5a7466 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 77 92 3.2E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0986 848d4092b258f1c540ddf6b06a5a7466 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 62 77 3.2E-13 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_1068 83d08199b41621787bcf7713a563f8d4 290 PIRSF PIRSF005651 2 290 3.0E-89 T 14-10-2018 IPR010200 HflC GO:0016021|GO:0052547 D521_1068 83d08199b41621787bcf7713a563f8d4 290 Pfam PF01145 SPFH domain / Band 7 family 26 201 5.6E-29 T 14-10-2018 IPR001107 Band 7 domain D521_1068 83d08199b41621787bcf7713a563f8d4 290 TIGRFAM TIGR01932 hflC: HflC protein 144 287 4.5E-47 T 14-10-2018 IPR010200 HflC GO:0016021|GO:0052547 D521_1068 83d08199b41621787bcf7713a563f8d4 290 Gene3D G3DSA:3.30.479.30 55 189 7.4E-22 T 14-10-2018 D521_1068 83d08199b41621787bcf7713a563f8d4 290 SMART SM00244 22 187 6.6E-25 T 14-10-2018 IPR001107 Band 7 domain D521_1068 83d08199b41621787bcf7713a563f8d4 290 SUPERFAMILY SSF117892 57 193 4.71E-26 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily D521_2031 e71e4402d9f28fb8bacfa6d35fd8cb65 47 Gene3D G3DSA:3.30.1200.10 1 46 5.9E-8 T 14-10-2018 IPR036591 YggU-like superfamily D521_2031 e71e4402d9f28fb8bacfa6d35fd8cb65 47 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 2 32 8.7E-8 T 14-10-2018 IPR003746 Protein of unknown function DUF167 D521_2031 e71e4402d9f28fb8bacfa6d35fd8cb65 47 SUPERFAMILY SSF69786 2 45 5.75E-8 T 14-10-2018 IPR036591 YggU-like superfamily D521_0602 40e2f257dfd9e1c3985ee5690f81e97e 341 Gene3D G3DSA:1.10.3720.10 123 329 2.6E-20 T 14-10-2018 IPR035906 MetI-like superfamily D521_0602 40e2f257dfd9e1c3985ee5690f81e97e 341 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 4 38 3.8E-5 T 14-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain D521_0602 40e2f257dfd9e1c3985ee5690f81e97e 341 SUPERFAMILY SSF161098 128 315 2.62E-22 T 14-10-2018 IPR035906 MetI-like superfamily D521_0602 40e2f257dfd9e1c3985ee5690f81e97e 341 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 151 332 6.2E-30 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 D521_1021 6600cae1e225d78ba5d315e1e25c8ae7 159 Pfam PF11911 Protein of unknown function (DUF3429) 5 151 7.0E-25 T 14-10-2018 IPR021836 Protein of unknown function DUF3429 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 SUPERFAMILY SSF52833 1 101 7.46E-24 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 Pfam PF13192 Thioredoxin domain 124 193 2.2E-11 T 14-10-2018 IPR012336 Thioredoxin-like fold D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 Gene3D G3DSA:3.50.50.60 212 504 4.0E-107 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PIRSF PIRSF000238 1 514 6.5E-253 T 14-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 Gene3D G3DSA:3.50.50.60 323 446 4.0E-107 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 SUPERFAMILY SSF51905 204 510 4.07E-48 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 341 361 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 SUPERFAMILY SSF52833 103 195 1.86E-24 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 213 500 2.3E-41 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 Gene3D G3DSA:3.40.30.80 1 199 2.1E-62 T 14-10-2018 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 438 454 6.5E-38 T 14-10-2018 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 311 329 6.5E-38 T 14-10-2018 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 214 233 6.5E-38 T 14-10-2018 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 464 486 6.5E-38 T 14-10-2018 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 353 371 6.5E-38 T 14-10-2018 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 1 513 1.0E-237 T 14-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 440 461 1.2E-63 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 265 275 1.2E-63 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 213 235 1.2E-63 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 401 417 1.2E-63 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 334 346 1.2E-63 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 312 320 1.2E-63 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 349 373 1.2E-63 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 474 492 1.2E-63 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0398 385ea4cf4948ed78e3730ef9c3299d11 514 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 245 260 1.2E-63 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 SUPERFAMILY SSF52540 78 622 8.4E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 SMART SM00490 500 586 7.9E-20 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 Gene3D G3DSA:3.40.50.300 455 636 2.2E-50 T 14-10-2018 D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 Pfam PF00271 Helicase conserved C-terminal domain 476 584 7.8E-18 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 SUPERFAMILY SSF46600 658 704 1.06E-9 T 14-10-2018 IPR036876 UVR domain superfamily D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 Gene3D G3DSA:3.40.50.300 45 275 1.6E-71 T 14-10-2018 D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 Gene3D G3DSA:3.40.50.300 311 454 6.3E-49 T 14-10-2018 D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 Hamap MF_00204 UvrABC system protein B [uvrB]. 44 703 42.357 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 Pfam PF12344 Ultra-violet resistance protein B 592 634 5.1E-20 T 14-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 SMART SM00487 50 466 1.5E-24 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 SUPERFAMILY SSF52540 45 455 7.71E-132 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 Gene3D G3DSA:4.10.860.10 648 708 4.7E-15 T 14-10-2018 D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 46 701 0.0 T 14-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 Pfam PF04851 Type III restriction enzyme, res subunit 58 180 9.0E-9 T 14-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 D521_1353 9d4fb348c7ba965a13ef57dfed6d860e 713 Pfam PF02151 UvrB/uvrC motif 670 702 4.8E-6 T 14-10-2018 IPR001943 UVR domain GO:0005515 D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 Gene3D G3DSA:3.40.50.720 6 253 1.5E-66 T 14-10-2018 D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 3.9E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 3.9E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 3.9E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 3.9E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 SUPERFAMILY SSF51735 6 232 9.34E-61 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 Pfam PF00106 short chain dehydrogenase 7 198 1.5E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 1.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 1.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1534 9730fad1c69545f46e483cbf8a051eb0 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 1.4E-10 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 473 496 - T 14-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 Pfam PF02875 Mur ligase family, glutamate ligase domain 711 792 2.0E-13 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 Gene3D G3DSA:3.90.190.20 715 854 2.6E-20 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 Pfam PF08443 RimK-like ATP-grasp domain 202 306 6.6E-5 T 14-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 SUPERFAMILY SSF53244 711 839 3.36E-25 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 2 853 0.0 T 14-10-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 Pfam PF08245 Mur ligase middle domain 475 687 1.3E-20 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 Gene3D G3DSA:3.40.1190.10 467 706 1.1E-37 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 SUPERFAMILY SSF53623 433 725 2.09E-40 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 Gene3D G3DSA:3.30.1490.20 204 287 1.7E-14 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 Gene3D G3DSA:3.30.470.20 360 462 1.4E-11 T 14-10-2018 D521_0534 da0a78bf2ae0690ecd420e82b6312357 856 SUPERFAMILY SSF56059 204 462 4.07E-29 T 14-10-2018 D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 Gene3D G3DSA:3.40.50.720 4 340 6.1E-166 T 14-10-2018 D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 SUPERFAMILY SSF55347 137 302 1.5E-52 T 14-10-2018 D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 6.1E-19 T 14-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 PIRSF PIRSF000098 1 435 4.3E-163 T 14-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 14-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 Gene3D G3DSA:3.30.70.260 349 423 6.1E-166 T 14-10-2018 D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 SUPERFAMILY SSF51735 1 158 1.38E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 Pfam PF01842 ACT domain 354 420 3.0E-12 T 14-10-2018 IPR002912 ACT domain D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 Pfam PF00742 Homoserine dehydrogenase 137 315 2.9E-64 T 14-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 SUPERFAMILY SSF55021 353 423 3.31E-11 T 14-10-2018 D521_1384 2ecfcf968185fc118014dfde5c56b76e 436 Gene3D G3DSA:3.30.360.10 136 348 6.1E-166 T 14-10-2018 D521_0845 ec510a041a3ecf4980de2f7777d2aca2 233 SUPERFAMILY SSF52172 81 152 7.55E-5 T 14-10-2018 IPR011006 CheY-like superfamily D521_0845 ec510a041a3ecf4980de2f7777d2aca2 233 Pfam PF12728 Helix-turn-helix domain 10 60 6.5E-8 T 14-10-2018 D521_0845 ec510a041a3ecf4980de2f7777d2aca2 233 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 10 55 3.0E-10 T 14-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 D521_0063 b16bf5dc4c464127096d99cc16c91404 102 SMART SM00739 3 30 4.6E-4 T 14-10-2018 IPR005824 KOW D521_0063 b16bf5dc4c464127096d99cc16c91404 102 Gene3D G3DSA:2.30.30.30 1 101 8.7E-32 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 D521_0063 b16bf5dc4c464127096d99cc16c91404 102 Pfam PF00467 KOW motif 6 31 7.7E-5 T 14-10-2018 IPR005824 KOW D521_0063 b16bf5dc4c464127096d99cc16c91404 102 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 94 17.938 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0063 b16bf5dc4c464127096d99cc16c91404 102 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 99 5.3E-30 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0063 b16bf5dc4c464127096d99cc16c91404 102 SUPERFAMILY SSF50104 3 97 4.71E-26 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily D521_0063 b16bf5dc4c464127096d99cc16c91404 102 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 37 99 2.2E-20 T 14-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1569 527202e90df8854dbafc03515d2a1daa 505 Pfam PF03441 FAD binding domain of DNA photolyase 266 462 6.0E-49 T 14-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 D521_1569 527202e90df8854dbafc03515d2a1daa 505 SUPERFAMILY SSF52425 6 159 4.32E-38 T 14-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 D521_1569 527202e90df8854dbafc03515d2a1daa 505 Gene3D G3DSA:1.10.579.10 286 503 2.4E-54 T 14-10-2018 D521_1569 527202e90df8854dbafc03515d2a1daa 505 Gene3D G3DSA:1.25.40.80 139 279 3.4E-15 T 14-10-2018 D521_1569 527202e90df8854dbafc03515d2a1daa 505 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 315 327 - T 14-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal D521_1569 527202e90df8854dbafc03515d2a1daa 505 Pfam PF00875 DNA photolyase 6 135 6.4E-24 T 14-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 D521_1569 527202e90df8854dbafc03515d2a1daa 505 Gene3D G3DSA:3.40.50.620 3 128 9.5E-27 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1569 527202e90df8854dbafc03515d2a1daa 505 SUPERFAMILY SSF48173 190 466 1.16E-71 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 D521_1000 73d1443be8354fefef4695ede0088297 275 SUPERFAMILY SSF55120 1 261 2.01E-83 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1000 73d1443be8354fefef4695ede0088297 275 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 1 253 33.942 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1000 73d1443be8354fefef4695ede0088297 275 Pfam PF01416 tRNA pseudouridine synthase 152 254 7.4E-28 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1000 73d1443be8354fefef4695ede0088297 275 Pfam PF01416 tRNA pseudouridine synthase 8 108 3.0E-6 T 14-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1000 73d1443be8354fefef4695ede0088297 275 Gene3D G3DSA:3.30.70.660 111 252 4.4E-43 T 14-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 D521_1000 73d1443be8354fefef4695ede0088297 275 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 248 9.0E-63 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1000 73d1443be8354fefef4695ede0088297 275 PIRSF PIRSF001430 1 263 9.3E-72 T 14-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1000 73d1443be8354fefef4695ede0088297 275 Gene3D G3DSA:3.30.70.580 1 110 8.4E-36 T 14-10-2018 D521_1333 92672a598cb7d18cbe251d57bda93e7b 336 Gene3D G3DSA:1.10.1530.10 12 325 7.6E-95 T 14-10-2018 D521_1333 92672a598cb7d18cbe251d57bda93e7b 336 Pfam PF02615 Malate/L-lactate dehydrogenase 5 327 1.2E-94 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 D521_1333 92672a598cb7d18cbe251d57bda93e7b 336 Gene3D G3DSA:3.30.60.50 177 224 7.6E-95 T 14-10-2018 D521_1333 92672a598cb7d18cbe251d57bda93e7b 336 Gene3D G3DSA:3.30.1370.60 61 299 7.6E-95 T 14-10-2018 D521_1333 92672a598cb7d18cbe251d57bda93e7b 336 SUPERFAMILY SSF89733 2 328 4.84E-91 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 431 579 3.3E-45 T 14-10-2018 IPR001162 UvrC family homology region D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 Pfam PF02151 UvrB/uvrC motif 206 238 2.3E-8 T 14-10-2018 IPR001943 UVR domain GO:0005515 D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 Hamap MF_00203 UvrABC system protein C [uvrC]. 6 644 26.518 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 Gene3D G3DSA:3.40.1440.10 5 104 2.2E-32 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 10 626 7.1E-164 T 14-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 Gene3D G3DSA:3.30.420.340 415 589 1.0E-45 T 14-10-2018 IPR038476 UvrC homology region 2 superfamily D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 SUPERFAMILY SSF47781 544 646 5.72E-19 T 14-10-2018 IPR010994 RuvA domain 2-like D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 SUPERFAMILY SSF46600 192 244 1.83E-12 T 14-10-2018 IPR036876 UVR domain superfamily D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 SMART SM00465 19 100 1.8E-19 T 14-10-2018 IPR000305 GIY-YIG endonuclease D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 Pfam PF01541 GIY-YIG catalytic domain 21 92 1.1E-9 T 14-10-2018 IPR000305 GIY-YIG endonuclease D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 SMART SM00278 593 612 0.51 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 SMART SM00278 625 644 48.0 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 SUPERFAMILY SSF82771 19 102 1.83E-20 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 D521_1413 0fc6c42139d838ec97f7e2c8e039936d 646 Gene3D G3DSA:1.10.150.20 592 646 3.5E-22 T 14-10-2018 D521_0239 355cd923aea80d262c46e25b7bf819ac 141 Pfam PF03653 Uncharacterised protein family (UPF0093) 2 141 2.1E-40 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 D521_0239 355cd923aea80d262c46e25b7bf819ac 141 PIRSF PIRSF004638 1 141 2.0E-44 T 14-10-2018 IPR005265 Uncharacterised protein family UPF0093 D521_1393 2ddf2f75be94ddc0758c4ed0b56056f7 155 PIRSF PIRSF000239 1 155 5.5E-27 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 D521_1393 2ddf2f75be94ddc0758c4ed0b56056f7 155 SUPERFAMILY SSF52833 4 153 2.25E-43 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1393 2ddf2f75be94ddc0758c4ed0b56056f7 155 Gene3D G3DSA:3.40.30.10 2 154 1.6E-39 T 14-10-2018 D521_1393 2ddf2f75be94ddc0758c4ed0b56056f7 155 Pfam PF00578 AhpC/TSA family 5 132 3.7E-27 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 D521_1762 ce9d30bb78f1255b5902935bbb4eb1c8 189 SUPERFAMILY SSF89028 7 182 1.0E-60 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 D521_1762 ce9d30bb78f1255b5902935bbb4eb1c8 189 Pfam PF01923 Cobalamin adenosyltransferase 8 169 2.7E-57 T 14-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 D521_1762 ce9d30bb78f1255b5902935bbb4eb1c8 189 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 182 2.0E-65 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 D521_1762 ce9d30bb78f1255b5902935bbb4eb1c8 189 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 10 182 8.3E-61 T 14-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 D521_1762 ce9d30bb78f1255b5902935bbb4eb1c8 189 Gene3D G3DSA:1.20.1200.10 17 187 5.9E-62 T 14-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 D521_0980 a398418ba6ea54df367568b947038e8f 212 SUPERFAMILY SSF46626 17 203 4.18E-13 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0980 a398418ba6ea54df367568b947038e8f 212 Pfam PF00034 Cytochrome c 123 203 6.1E-6 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0980 a398418ba6ea54df367568b947038e8f 212 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 126 205 2.3E-25 T 14-10-2018 IPR030999 Sulfur oxidation c-type cytochrome SoxX D521_0980 a398418ba6ea54df367568b947038e8f 212 Gene3D G3DSA:1.10.760.10 29 212 2.0E-68 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0980 a398418ba6ea54df367568b947038e8f 212 PIRSF PIRSF024608 1 212 1.6E-61 T 14-10-2018 IPR016823 Sulfur oxidation c-type cytochrome SoxX, type II D521_0694 e214512839283225337a6c4fc205b84c 600 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 46 181 3.8E-24 T 14-10-2018 D521_0694 e214512839283225337a6c4fc205b84c 600 Gene3D G3DSA:3.40.30.10 108 182 5.8E-10 T 14-10-2018 D521_0694 e214512839283225337a6c4fc205b84c 600 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 536 547 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0694 e214512839283225337a6c4fc205b84c 600 SUPERFAMILY SSF142984 435 517 5.75E-21 T 14-10-2018 D521_0694 e214512839283225337a6c4fc205b84c 600 SUPERFAMILY SSF142019 214 433 1.83E-65 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0694 e214512839283225337a6c4fc205b84c 600 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 361 376 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0694 e214512839283225337a6c4fc205b84c 600 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 524 599 1.8E-21 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0694 e214512839283225337a6c4fc205b84c 600 SUPERFAMILY SSF52833 38 186 3.35E-32 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0694 e214512839283225337a6c4fc205b84c 600 Gene3D G3DSA:3.10.20.600 426 520 4.6E-25 T 14-10-2018 D521_0694 e214512839283225337a6c4fc205b84c 600 SUPERFAMILY SSF140490 523 599 6.15E-25 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0694 e214512839283225337a6c4fc205b84c 600 Pfam PF10531 SLBB domain 438 486 1.1E-9 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0694 e214512839283225337a6c4fc205b84c 600 SMART SM00928 523 568 3.6E-19 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0694 e214512839283225337a6c4fc205b84c 600 Gene3D G3DSA:3.40.50.11540 256 425 1.9E-62 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0694 e214512839283225337a6c4fc205b84c 600 Gene3D G3DSA:1.20.1440.230 522 600 1.4E-23 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0694 e214512839283225337a6c4fc205b84c 600 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 252 412 2.5E-37 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0694 e214512839283225337a6c4fc205b84c 600 Gene3D G3DSA:1.10.10.1590 38 104 4.7E-7 T 14-10-2018 D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 11 941 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 PIRSF PIRSF000157 1 944 0.0 T 14-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 Gene3D G3DSA:1.10.287.1150 88 169 8.7E-24 T 14-10-2018 D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 SUPERFAMILY SSF52518 581 801 7.32E-49 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 SMART SM00861 598 795 2.0E-61 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 SUPERFAMILY SSF52518 124 550 2.72E-84 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 800 942 8.2E-54 T 14-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 Gene3D G3DSA:3.40.50.12470 562 811 1.6E-169 T 14-10-2018 D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 9 45 1.2E-16 T 14-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 Gene3D G3DSA:3.40.50.11610 732 938 1.6E-169 T 14-10-2018 D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 Pfam PF00676 Dehydrogenase E1 component 218 521 4.3E-44 T 14-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 Pfam PF02779 Transketolase, pyrimidine binding domain 598 795 9.5E-66 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain D521_0846 a4f7acf869319d38ebcbd9f20b798817 952 Gene3D G3DSA:3.40.50.970 170 530 1.2E-136 T 14-10-2018 D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 SUPERFAMILY SSF56235 26 451 3.69E-153 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 SUPERFAMILY SSF51395 479 1276 8.96E-265 T 14-10-2018 D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 Pfam PF00310 Glutamine amidotransferases class-II 26 449 6.2E-186 T 14-10-2018 IPR017932 Glutamine amidotransferase type 2 domain D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 Gene3D G3DSA:3.20.20.70 814 1280 1.8E-203 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 Gene3D G3DSA:3.60.20.10 26 460 3.3E-182 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 Pfam PF04898 Glutamate synthase central domain 483 769 8.3E-114 T 14-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 Pfam PF01645 Conserved region in glutamate synthase 830 1230 1.1E-153 T 14-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 SUPERFAMILY SSF69336 1279 1569 7.32E-95 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 Gene3D G3DSA:3.20.20.70 461 813 9.1E-127 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 Pfam PF01493 GXGXG motif 1310 1493 5.0E-81 T 14-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 D521_0093 1d6c794e11cfaf4b5c0b16e44d928191 1581 Gene3D G3DSA:2.160.20.60 1282 1580 1.4E-111 T 14-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 D521_0991 f7310a013d7ac949781d147754c481aa 402 Gene3D G3DSA:3.90.1150.10 270 402 8.0E-50 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_0991 f7310a013d7ac949781d147754c481aa 402 Gene3D G3DSA:3.40.640.10 2 268 4.6E-85 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0991 f7310a013d7ac949781d147754c481aa 402 PIRSF PIRSF001434 3 402 2.0E-133 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 D521_0991 f7310a013d7ac949781d147754c481aa 402 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 19 401 53.895 T 14-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 D521_0991 f7310a013d7ac949781d147754c481aa 402 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 210 224 - T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 D521_0991 f7310a013d7ac949781d147754c481aa 402 SUPERFAMILY SSF53383 39 401 4.57E-122 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0991 f7310a013d7ac949781d147754c481aa 402 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 18 400 5.7E-142 T 14-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 D521_0991 f7310a013d7ac949781d147754c481aa 402 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 18 399 1.3E-169 T 14-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 D521_1876 8a7def3e5c7cce02f66e85ea5d2f2c51 376 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 6 376 39.275 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 D521_1876 8a7def3e5c7cce02f66e85ea5d2f2c51 376 SUPERFAMILY SSF53067 7 349 5.83E-25 T 14-10-2018 D521_1876 8a7def3e5c7cce02f66e85ea5d2f2c51 376 Gene3D G3DSA:3.30.420.40 150 336 5.0E-118 T 14-10-2018 D521_1876 8a7def3e5c7cce02f66e85ea5d2f2c51 376 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 7 376 3.2E-128 T 14-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 D521_1876 8a7def3e5c7cce02f66e85ea5d2f2c51 376 Gene3D G3DSA:3.30.420.40 13 371 5.0E-118 T 14-10-2018 D521_0103 d10ae0774f9983342bd0c18c64d4b3ff 82 Pfam PF01722 BolA-like protein 22 75 1.1E-19 T 14-10-2018 IPR002634 BolA protein D521_0103 d10ae0774f9983342bd0c18c64d4b3ff 82 Gene3D G3DSA:3.30.300.90 2 79 9.3E-29 T 14-10-2018 D521_0103 d10ae0774f9983342bd0c18c64d4b3ff 82 PIRSF PIRSF003113 1 82 2.6E-22 T 14-10-2018 IPR002634 BolA protein D521_0103 d10ae0774f9983342bd0c18c64d4b3ff 82 SUPERFAMILY SSF82657 1 79 5.49E-28 T 14-10-2018 IPR036065 BolA-like superfamily D521_1658 3f829990abe9bb181850af87fb3a054c 102 Pfam PF11604 Copper binding periplasmic protein CusF 34 97 2.5E-23 T 14-10-2018 IPR021647 Copper binding periplasmic protein CusF D521_1658 3f829990abe9bb181850af87fb3a054c 102 Gene3D G3DSA:2.40.50.320 30 101 2.0E-23 T 14-10-2018 D521_1887 193f44c50ddf706e512456141f512b6b 599 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 3 591 2.0E-243 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 D521_1887 193f44c50ddf706e512456141f512b6b 599 Gene3D G3DSA:3.30.930.10 120 591 3.8E-196 T 14-10-2018 D521_1887 193f44c50ddf706e512456141f512b6b 599 Gene3D G3DSA:3.30.1360.30 275 429 3.8E-196 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 D521_1887 193f44c50ddf706e512456141f512b6b 599 SUPERFAMILY SSF55261 294 419 1.36E-42 T 14-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 D521_1887 193f44c50ddf706e512456141f512b6b 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 527 541 8.4E-27 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1887 193f44c50ddf706e512456141f512b6b 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 193 205 8.4E-27 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1887 193f44c50ddf706e512456141f512b6b 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 483 499 8.4E-27 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1887 193f44c50ddf706e512456141f512b6b 599 PRINTS PR01042 Aspartyl-tRNA synthetase signature 210 223 8.4E-27 T 14-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1887 193f44c50ddf706e512456141f512b6b 599 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 593 33.216 T 14-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 D521_1887 193f44c50ddf706e512456141f512b6b 599 Pfam PF02938 GAD domain 311 409 8.2E-29 T 14-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 D521_1887 193f44c50ddf706e512456141f512b6b 599 SUPERFAMILY SSF50249 3 107 4.0E-33 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1887 193f44c50ddf706e512456141f512b6b 599 SUPERFAMILY SSF55681 113 593 4.38E-106 T 14-10-2018 D521_1887 193f44c50ddf706e512456141f512b6b 599 Pfam PF01336 OB-fold nucleic acid binding domain 21 103 1.4E-15 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 D521_1887 193f44c50ddf706e512456141f512b6b 599 Gene3D G3DSA:2.40.50.140 1 107 8.7E-36 T 14-10-2018 D521_1887 193f44c50ddf706e512456141f512b6b 599 Pfam PF00152 tRNA synthetases class II (D, K and N) 121 567 2.2E-108 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0747 1c1201b6e05ebd96734ed4ca374092d4 160 SUPERFAMILY SSF56770 9 153 1.7E-67 T 14-10-2018 D521_0747 1c1201b6e05ebd96734ed4ca374092d4 160 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0747 1c1201b6e05ebd96734ed4ca374092d4 160 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 6.4E-78 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0747 1c1201b6e05ebd96734ed4ca374092d4 160 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.516 T 14-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0747 1c1201b6e05ebd96734ed4ca374092d4 160 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 3.2E-23 T 14-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0747 1c1201b6e05ebd96734ed4ca374092d4 160 Gene3D G3DSA:3.40.50.12280 2 160 1.2E-79 T 14-10-2018 D521_0213 232c620b9e8193f42d130c138b2e3352 153 Pfam PF00364 Biotin-requiring enzyme 81 152 1.6E-23 T 14-10-2018 IPR000089 Biotin/lipoyl attachment D521_0213 232c620b9e8193f42d130c138b2e3352 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 114 127 2.3E-19 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 D521_0213 232c620b9e8193f42d130c138b2e3352 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 99 113 2.3E-19 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 D521_0213 232c620b9e8193f42d130c138b2e3352 153 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 82 95 2.3E-19 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 D521_0213 232c620b9e8193f42d130c138b2e3352 153 SUPERFAMILY SSF51230 80 152 2.49E-23 T 14-10-2018 IPR011053 Single hybrid motif D521_0213 232c620b9e8193f42d130c138b2e3352 153 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 152 4.8E-52 T 14-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 D521_0213 232c620b9e8193f42d130c138b2e3352 153 Gene3D G3DSA:2.40.50.100 76 152 4.9E-29 T 14-10-2018 D521_0213 232c620b9e8193f42d130c138b2e3352 153 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 109 126 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 1.1E-29 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 ProSitePatterns PS01242 Zinc finger FPG-type signature. 252 276 - T 14-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 SMART SM00898 2 115 2.9E-46 T 14-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 SUPERFAMILY SSF57716 225 277 3.42E-16 T 14-10-2018 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 133 226 3.2E-19 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 Gene3D G3DSA:3.20.190.10 2 126 1.4E-34 T 14-10-2018 IPR035937 MutM-like, N-terminal D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 SMART SM01232 133 229 5.7E-40 T 14-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 277 39.97 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 SUPERFAMILY SSF46946 134 230 7.2E-24 T 14-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 SUPERFAMILY SSF81624 2 142 2.88E-37 T 14-10-2018 IPR035937 MutM-like, N-terminal D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 276 2.3E-82 T 14-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 Pfam PF06827 Zinc finger found in FPG and IleRS 250 278 1.2E-11 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 D521_1914 26b4efb38265b70247fb3ba86d830c9a 278 Gene3D G3DSA:1.10.8.50 148 277 8.5E-43 T 14-10-2018 D521_1825 ad448d7579e9f1ed119747f3407aacf6 165 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site D521_1825 ad448d7579e9f1ed119747f3407aacf6 165 Pfam PF00114 Pilin (bacterial filament) 40 162 7.6E-16 T 14-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 D521_1825 ad448d7579e9f1ed119747f3407aacf6 165 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 32 2.4E-8 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site D521_1825 ad448d7579e9f1ed119747f3407aacf6 165 SUPERFAMILY SSF54523 12 120 7.32E-21 T 14-10-2018 D521_1825 ad448d7579e9f1ed119747f3407aacf6 165 Gene3D G3DSA:3.30.700.10 12 165 8.1E-29 T 14-10-2018 D521_1825 ad448d7579e9f1ed119747f3407aacf6 165 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 31 1.6E-9 T 14-10-2018 IPR012902 Prokaryotic N-terminal methylation site D521_0581 9e8162bb969c20e3bbdfe587378f1226 312 SUPERFAMILY SSF48179 187 298 3.74E-21 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_0581 9e8162bb969c20e3bbdfe587378f1226 312 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 185 209 - T 14-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 D521_0581 9e8162bb969c20e3bbdfe587378f1226 312 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 185 5.9E-41 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 D521_0581 9e8162bb969c20e3bbdfe587378f1226 312 SUPERFAMILY SSF51735 3 184 5.98E-35 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0581 9e8162bb969c20e3bbdfe587378f1226 312 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 286 7.8E-18 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 D521_0581 9e8162bb969c20e3bbdfe587378f1226 312 Gene3D G3DSA:1.10.1040.10 191 310 1.9E-32 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 D521_0581 9e8162bb969c20e3bbdfe587378f1226 312 Gene3D G3DSA:3.40.50.720 1 190 5.4E-46 T 14-10-2018 D521_0581 9e8162bb969c20e3bbdfe587378f1226 312 PIRSF PIRSF000105 1 311 9.2E-71 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 D521_1807 a5e8c44c17bd0959df292a7138d03d73 394 Pfam PF02222 ATP-grasp domain 126 292 2.1E-47 T 14-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type D521_1807 a5e8c44c17bd0959df292a7138d03d73 394 Gene3D G3DSA:3.30.1490.20 126 191 3.7E-19 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 D521_1807 a5e8c44c17bd0959df292a7138d03d73 394 SUPERFAMILY SSF52440 8 107 8.34E-26 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily D521_1807 a5e8c44c17bd0959df292a7138d03d73 394 SUPERFAMILY SSF51246 316 389 4.0E-16 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 D521_1807 a5e8c44c17bd0959df292a7138d03d73 394 Gene3D G3DSA:3.30.470.20 192 390 7.0E-74 T 14-10-2018 D521_1807 a5e8c44c17bd0959df292a7138d03d73 394 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 14 381 4.4E-110 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 D521_1807 a5e8c44c17bd0959df292a7138d03d73 394 Gene3D G3DSA:3.40.50.20 6 119 3.6E-37 T 14-10-2018 D521_1807 a5e8c44c17bd0959df292a7138d03d73 394 SUPERFAMILY SSF56059 110 312 5.21E-53 T 14-10-2018 D521_1807 a5e8c44c17bd0959df292a7138d03d73 394 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 13 376 38.97 T 14-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 D521_0113 c3fe14fe04aad373b4727e8daa258899 133 SUPERFAMILY SSF101386 33 116 3.18E-18 T 14-10-2018 D521_0113 c3fe14fe04aad373b4727e8daa258899 133 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 12 112 19.325 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 D521_0113 c3fe14fe04aad373b4727e8daa258899 133 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 16 112 1.1E-24 T 14-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 D521_0113 c3fe14fe04aad373b4727e8daa258899 133 Gene3D G3DSA:1.10.287.1080 12 118 3.2E-25 T 14-10-2018 D521_0113 c3fe14fe04aad373b4727e8daa258899 133 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 28 115 3.9E-12 T 14-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 Gene3D G3DSA:3.30.2090.10 694 782 7.5E-280 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 SUPERFAMILY SSF82693 553 647 4.45E-18 T 14-10-2018 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 Gene3D G3DSA:1.20.1640.10 10 500 7.5E-280 T 14-10-2018 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 Gene3D G3DSA:3.30.70.1320 134 325 7.5E-280 T 14-10-2018 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 Gene3D G3DSA:3.30.70.1430 40 790 7.5E-280 T 14-10-2018 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 SUPERFAMILY SSF82866 290 487 3.01E-47 T 14-10-2018 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 SUPERFAMILY SSF82866 784 1000 2.22E-43 T 14-10-2018 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 SUPERFAMILY SSF82714 695 779 1.7E-17 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 Gene3D G3DSA:3.30.2090.10 178 268 7.5E-280 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 SUPERFAMILY SSF82714 184 265 4.71E-13 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 SUPERFAMILY SSF82693 138 323 2.22E-21 T 14-10-2018 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 Gene3D G3DSA:1.20.1640.10 501 996 7.5E-280 T 14-10-2018 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 SUPERFAMILY SSF82693 44 130 6.8E-22 T 14-10-2018 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 Pfam PF00873 AcrB/AcrD/AcrF family 5 999 1.9E-260 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 3.8E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 PRINTS PR00702 Acriflavin resistance protein family signature 540 557 3.8E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.8E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 PRINTS PR00702 Acriflavin resistance protein family signature 356 377 3.8E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 PRINTS PR00702 Acriflavin resistance protein family signature 384 408 3.8E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 3.8E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.8E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 3.8E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 PRINTS PR00702 Acriflavin resistance protein family signature 600 614 3.8E-76 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 Gene3D G3DSA:3.30.70.1440 645 839 7.5E-280 T 14-10-2018 D521_1986 979d4c47d7a4d8bb9926c73fa642d7d3 1011 Gene3D G3DSA:3.30.70.1430 555 644 7.5E-280 T 14-10-2018 D521_0197 e0e439a411f83a96e881a0be063bf5c7 86 SUPERFAMILY SSF110324 2 79 2.62E-32 T 14-10-2018 D521_0197 e0e439a411f83a96e881a0be063bf5c7 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 14-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0197 e0e439a411f83a96e881a0be063bf5c7 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 2.7E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0197 e0e439a411f83a96e881a0be063bf5c7 86 Gene3D G3DSA:2.40.50.1030 6 84 5.5E-28 T 14-10-2018 D521_0197 e0e439a411f83a96e881a0be063bf5c7 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 71 9.0E-15 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0197 e0e439a411f83a96e881a0be063bf5c7 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 5.8E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0197 e0e439a411f83a96e881a0be063bf5c7 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 5.8E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0197 e0e439a411f83a96e881a0be063bf5c7 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 5.8E-38 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0197 e0e439a411f83a96e881a0be063bf5c7 86 Pfam PF01016 Ribosomal L27 protein 2 81 7.0E-36 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0197 e0e439a411f83a96e881a0be063bf5c7 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.29 T 14-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0859 027fadce1846a90d9752bb27f15c2044 250 SUPERFAMILY SSF75217 11 165 2.55E-27 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases D521_0859 027fadce1846a90d9752bb27f15c2044 250 Pfam PF00588 SpoU rRNA Methylase family 10 161 1.0E-27 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 D521_0859 027fadce1846a90d9752bb27f15c2044 250 PIRSF PIRSF004808 5 249 9.4E-57 T 14-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 D521_0859 027fadce1846a90d9752bb27f15c2044 250 Gene3D G3DSA:1.10.8.590 185 247 7.6E-18 T 14-10-2018 D521_0859 027fadce1846a90d9752bb27f15c2044 250 Gene3D G3DSA:3.40.1280.10 5 173 4.4E-50 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal D521_0212 24cc850f295beabaaa748c83cae93d08 456 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 109 1.3E-44 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 D521_0212 24cc850f295beabaaa748c83cae93d08 456 SUPERFAMILY SSF56059 83 350 1.22E-71 T 14-10-2018 D521_0212 24cc850f295beabaaa748c83cae93d08 456 Gene3D G3DSA:3.30.470.20 87 433 6.1E-151 T 14-10-2018 D521_0212 24cc850f295beabaaa748c83cae93d08 456 SUPERFAMILY SSF52440 1 113 1.29E-47 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily D521_0212 24cc850f295beabaaa748c83cae93d08 456 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 446 2.4E-224 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 D521_0212 24cc850f295beabaaa748c83cae93d08 456 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 1.7E-81 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0212 24cc850f295beabaaa748c83cae93d08 456 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0212 24cc850f295beabaaa748c83cae93d08 456 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0212 24cc850f295beabaaa748c83cae93d08 456 Gene3D G3DSA:3.40.50.20 1 85 1.9E-34 T 14-10-2018 D521_0212 24cc850f295beabaaa748c83cae93d08 456 SMART SM00878 336 441 3.3E-62 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 D521_0212 24cc850f295beabaaa748c83cae93d08 456 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 2.5E-37 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 D521_0212 24cc850f295beabaaa748c83cae93d08 456 SUPERFAMILY SSF51246 331 445 8.37E-42 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 D521_0212 24cc850f295beabaaa748c83cae93d08 456 Gene3D G3DSA:3.30.1490.20 131 203 6.1E-151 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 D521_2016 54a1df1f04c9391b579de79268ddacd5 162 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 120 154 2.7E-10 T 14-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 D521_2016 54a1df1f04c9391b579de79268ddacd5 162 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 44 152 4.5E-43 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 D521_2016 54a1df1f04c9391b579de79268ddacd5 162 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 125 149 - T 14-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site D521_2016 54a1df1f04c9391b579de79268ddacd5 162 SUPERFAMILY SSF57716 122 160 4.7E-8 T 14-10-2018 D521_2016 54a1df1f04c9391b579de79268ddacd5 162 Gene3D G3DSA:1.20.120.910 29 160 3.0E-38 T 14-10-2018 D521_2016 54a1df1f04c9391b579de79268ddacd5 162 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 40 161 27.749 T 14-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 D521_2016 54a1df1f04c9391b579de79268ddacd5 162 SUPERFAMILY SSF109635 30 121 4.58E-30 T 14-10-2018 IPR037187 DksA, N-terminal domain superfamily D521_0310 50fdd4801d592b388a7ae471d33acfd8 324 Pfam PF01370 NAD dependent epimerase/dehydratase family 8 252 2.6E-75 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 D521_0310 50fdd4801d592b388a7ae471d33acfd8 324 SUPERFAMILY SSF51735 6 320 7.65E-71 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0310 50fdd4801d592b388a7ae471d33acfd8 324 Gene3D G3DSA:3.90.25.10 174 316 3.6E-105 T 14-10-2018 D521_0310 50fdd4801d592b388a7ae471d33acfd8 324 Gene3D G3DSA:3.40.50.720 8 309 3.6E-105 T 14-10-2018 D521_0310 50fdd4801d592b388a7ae471d33acfd8 324 Hamap MF_00956 GDP-L-fucose synthase [fcl]. 5 320 48.264 T 14-10-2018 IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase GO:0009226|GO:0016491 KEGG: 00051+1.1.1.271|KEGG: 00520+1.1.1.271|MetaCyc: PWY-66|Reactome: R-HSA-6787639 D521_0164 3015e0a08cfc1c30b1d0843b66d86cdb 590 Gene3D G3DSA:3.30.450.330 230 550 4.4E-108 T 14-10-2018 D521_0164 3015e0a08cfc1c30b1d0843b66d86cdb 590 Gene3D G3DSA:3.40.710.10 289 471 4.4E-108 T 14-10-2018 D521_0164 3015e0a08cfc1c30b1d0843b66d86cdb 590 Gene3D G3DSA:3.90.1310.30 57 228 5.2E-46 T 14-10-2018 D521_0164 3015e0a08cfc1c30b1d0843b66d86cdb 590 Hamap MF_02080 Peptidoglycan D,D-transpeptidase FtsI [ftsI]. 16 564 41.44 T 14-10-2018 IPR037532 Peptidoglycan D,D-transpeptidase FtsI GO:0005887|GO:0008658|GO:0008955|GO:0009252|GO:0051301 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 D521_0164 3015e0a08cfc1c30b1d0843b66d86cdb 590 SUPERFAMILY SSF56601 180 559 1.88E-87 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like D521_0164 3015e0a08cfc1c30b1d0843b66d86cdb 590 Pfam PF03717 Penicillin-binding Protein dimerisation domain 64 212 8.8E-22 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 D521_0164 3015e0a08cfc1c30b1d0843b66d86cdb 590 SUPERFAMILY SSF56519 60 227 3.92E-43 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 D521_0164 3015e0a08cfc1c30b1d0843b66d86cdb 590 Pfam PF00905 Penicillin binding protein transpeptidase domain 253 548 7.5E-70 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 D521_1003 80cf65684360a07a880d363332eb5f6d 357 SUPERFAMILY SSF53659 1 355 9.36E-122 T 14-10-2018 D521_1003 80cf65684360a07a880d363332eb5f6d 357 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 1 355 50.821 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 D521_1003 80cf65684360a07a880d363332eb5f6d 357 Gene3D G3DSA:3.40.718.10 1 355 2.5E-155 T 14-10-2018 D521_1003 80cf65684360a07a880d363332eb5f6d 357 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 D521_1003 80cf65684360a07a880d363332eb5f6d 357 SMART SM01329 2 351 5.6E-207 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 D521_1003 80cf65684360a07a880d363332eb5f6d 357 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 2 351 1.3E-132 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 D521_1003 80cf65684360a07a880d363332eb5f6d 357 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 2 350 7.9E-148 T 14-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 D521_0742 427b81b9dae51b543c07871bbdca3214 721 SUPERFAMILY SSF54211 294 489 1.06E-49 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0742 427b81b9dae51b543c07871bbdca3214 721 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 692 0.0 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Pfam PF03725 3' exoribonuclease family, domain 2 462 530 7.6E-5 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Pfam PF03725 3' exoribonuclease family, domain 2 149 212 7.1E-11 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Gene3D G3DSA:2.40.50.140 623 694 5.1E-25 T 14-10-2018 D521_0742 427b81b9dae51b543c07871bbdca3214 721 SUPERFAMILY SSF50249 621 697 1.56E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_0742 427b81b9dae51b543c07871bbdca3214 721 Gene3D G3DSA:3.30.1370.10 551 622 5.6E-22 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 D521_0742 427b81b9dae51b543c07871bbdca3214 721 SUPERFAMILY SSF54211 3 146 2.99E-50 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0742 427b81b9dae51b543c07871bbdca3214 721 SMART SM00322 553 618 4.2E-15 T 14-10-2018 IPR004087 K Homology domain GO:0003676 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Pfam PF00013 KH domain 558 614 1.6E-11 T 14-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 D521_0742 427b81b9dae51b543c07871bbdca3214 721 SUPERFAMILY SSF54791 556 641 1.02E-22 T 14-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Gene3D G3DSA:3.30.230.70 1 231 2.1E-79 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Gene3D G3DSA:3.30.230.70 237 550 4.5E-117 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0742 427b81b9dae51b543c07871bbdca3214 721 PIRSF PIRSF005499 3 718 5.2E-292 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 246 321 2.4E-19 T 14-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 5 694 29.807 T 14-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 D521_0742 427b81b9dae51b543c07871bbdca3214 721 SMART SM00316 621 691 2.5E-22 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_0742 427b81b9dae51b543c07871bbdca3214 721 SUPERFAMILY SSF55666 451 549 4.77E-28 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0742 427b81b9dae51b543c07871bbdca3214 721 SUPERFAMILY SSF55666 147 236 1.4E-28 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Pfam PF01138 3' exoribonuclease family, domain 1 325 457 1.3E-22 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Pfam PF01138 3' exoribonuclease family, domain 1 17 146 2.5E-18 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0742 427b81b9dae51b543c07871bbdca3214 721 Pfam PF00575 S1 RNA binding domain 620 691 2.2E-13 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_1360 3f1c2a2459950d8412e150c3200412ef 308 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 9 303 3.1E-100 T 14-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 D521_1360 3f1c2a2459950d8412e150c3200412ef 308 Gene3D G3DSA:3.40.50.150 35 205 4.0E-37 T 14-10-2018 D521_1360 3f1c2a2459950d8412e150c3200412ef 308 PIRSF PIRSF018005 2 308 2.7E-97 T 14-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 D521_1360 3f1c2a2459950d8412e150c3200412ef 308 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 10 304 1.9E-88 T 14-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent D521_1360 3f1c2a2459950d8412e150c3200412ef 308 SUPERFAMILY SSF53335 33 302 1.24E-9 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1311 e439bdc1d3469e27eb7528abb15ed57a 451 SUPERFAMILY SSF56349 173 410 7.65E-33 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_1311 e439bdc1d3469e27eb7528abb15ed57a 451 Gene3D G3DSA:3.30.160.390 12 117 5.4E-10 T 14-10-2018 IPR038488 Integrase, DNA-binding domain superfamily D521_1311 e439bdc1d3469e27eb7528abb15ed57a 451 Pfam PF00589 Phage integrase family 254 409 3.5E-13 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 D521_1311 e439bdc1d3469e27eb7528abb15ed57a 451 Gene3D G3DSA:1.10.443.10 249 417 7.1E-21 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 D521_1311 e439bdc1d3469e27eb7528abb15ed57a 451 Pfam PF13356 Arm DNA-binding domain 9 98 1.3E-12 T 14-10-2018 IPR025166 Integrase, DNA-binding domain D521_1709 471b8c8b205536aa217b6b847a23346d 874 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 654 696 1.1E-16 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 D521_1709 471b8c8b205536aa217b6b847a23346d 874 Gene3D G3DSA:3.30.930.10 1 248 1.3E-119 T 14-10-2018 D521_1709 471b8c8b205536aa217b6b847a23346d 874 Gene3D G3DSA:3.30.54.20 625 677 1.4E-50 T 14-10-2018 D521_1709 471b8c8b205536aa217b6b847a23346d 874 SMART SM00863 654 696 1.0E-18 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 D521_1709 471b8c8b205536aa217b6b847a23346d 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 205 216 8.3E-31 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 D521_1709 471b8c8b205536aa217b6b847a23346d 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 307 320 8.3E-31 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 D521_1709 471b8c8b205536aa217b6b847a23346d 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 283 299 8.3E-31 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 D521_1709 471b8c8b205536aa217b6b847a23346d 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 8.3E-31 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 D521_1709 471b8c8b205536aa217b6b847a23346d 874 PRINTS PR00980 Alanyl-tRNA synthetase signature 232 245 8.3E-31 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 D521_1709 471b8c8b205536aa217b6b847a23346d 874 Gene3D G3DSA:2.40.30.130 457 553 1.8E-9 T 14-10-2018 D521_1709 471b8c8b205536aa217b6b847a23346d 874 SUPERFAMILY SSF50447 454 553 1.55E-17 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily D521_1709 471b8c8b205536aa217b6b847a23346d 874 Gene3D G3DSA:3.30.980.10 563 697 1.4E-50 T 14-10-2018 D521_1709 471b8c8b205536aa217b6b847a23346d 874 SUPERFAMILY SSF55186 553 708 2.62E-48 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 D521_1709 471b8c8b205536aa217b6b847a23346d 874 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 854 0.0 T 14-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 D521_1709 471b8c8b205536aa217b6b847a23346d 874 Gene3D G3DSA:3.10.310.40 764 873 5.2E-29 T 14-10-2018 D521_1709 471b8c8b205536aa217b6b847a23346d 874 SUPERFAMILY SSF55681 2 251 3.48E-109 T 14-10-2018 D521_1709 471b8c8b205536aa217b6b847a23346d 874 SUPERFAMILY SSF101353 252 445 3.66E-58 T 14-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 D521_1709 471b8c8b205536aa217b6b847a23346d 874 Pfam PF01411 tRNA synthetases class II (A) 5 555 4.5E-221 T 14-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 D521_1709 471b8c8b205536aa217b6b847a23346d 874 Pfam PF02272 DHHA1 domain 733 871 6.8E-27 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 D521_1709 471b8c8b205536aa217b6b847a23346d 874 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 874 198.195 T 14-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 D521_0504 ddf6c599d35d02c11fc7194b99ceb038 700 Gene3D G3DSA:2.40.170.20 177 700 1.9E-43 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily D521_0504 ddf6c599d35d02c11fc7194b99ceb038 700 Pfam PF00593 TonB dependent receptor 232 699 1.7E-17 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel D521_0504 ddf6c599d35d02c11fc7194b99ceb038 700 Gene3D G3DSA:2.170.130.10 25 159 1.3E-34 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily D521_0504 ddf6c599d35d02c11fc7194b99ceb038 700 SUPERFAMILY SSF56935 29 700 2.78E-82 T 14-10-2018 D521_0504 ddf6c599d35d02c11fc7194b99ceb038 700 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 154 4.7E-23 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain D521_0647 a341447067ab1d2b73218896130ad50b 505 Pfam PF02743 Cache domain 100 224 9.3E-15 T 14-10-2018 IPR033479 Double Cache domain 1 D521_0647 a341447067ab1d2b73218896130ad50b 505 Gene3D G3DSA:3.30.450.20 194 292 2.2E-10 T 14-10-2018 D521_0647 a341447067ab1d2b73218896130ad50b 505 SUPERFAMILY SSF55073 343 500 2.12E-49 T 14-10-2018 IPR029787 Nucleotide cyclase D521_0647 a341447067ab1d2b73218896130ad50b 505 SMART SM00267 327 499 2.9E-59 T 14-10-2018 IPR000160 GGDEF domain D521_0647 a341447067ab1d2b73218896130ad50b 505 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 336 498 1.1E-40 T 14-10-2018 IPR000160 GGDEF domain D521_0647 a341447067ab1d2b73218896130ad50b 505 Pfam PF00990 Diguanylate cyclase, GGDEF domain 338 495 7.8E-44 T 14-10-2018 IPR000160 GGDEF domain D521_0647 a341447067ab1d2b73218896130ad50b 505 SUPERFAMILY SSF103190 135 196 5.3E-5 T 14-10-2018 IPR029151 Periplasmic sensor-like domain superfamily D521_0647 a341447067ab1d2b73218896130ad50b 505 Gene3D G3DSA:3.30.70.270 333 502 1.5E-55 T 14-10-2018 D521_0647 a341447067ab1d2b73218896130ad50b 505 Gene3D G3DSA:3.30.450.20 33 191 3.3E-29 T 14-10-2018 D521_0355 80ed4f4f1118c98f7bc8347af969211a 256 Pfam PF01925 Sulfite exporter TauE/SafE 2 246 4.3E-40 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 D521_0158 9e2f0e98cd4d87b0a10669293b6ddace 448 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 20 443 7.6E-160 T 14-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 D521_0158 9e2f0e98cd4d87b0a10669293b6ddace 448 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 257 294 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_0158 9e2f0e98cd4d87b0a10669293b6ddace 448 Pfam PF00202 Aminotransferase class-III 32 441 3.6E-114 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_0158 9e2f0e98cd4d87b0a10669293b6ddace 448 PIRSF PIRSF000521 19 446 1.1E-32 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_0158 9e2f0e98cd4d87b0a10669293b6ddace 448 SUPERFAMILY SSF53383 17 444 5.09E-116 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0158 9e2f0e98cd4d87b0a10669293b6ddace 448 Gene3D G3DSA:3.40.640.10 70 346 1.5E-147 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0158 9e2f0e98cd4d87b0a10669293b6ddace 448 Gene3D G3DSA:3.90.1150.10 19 435 1.5E-147 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_1579 395021ba7f4d78e72c652d52c29f17e9 295 SUPERFAMILY SSF46785 2 112 5.99E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1579 395021ba7f4d78e72c652d52c29f17e9 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 63 6.8E-16 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_1579 395021ba7f4d78e72c652d52c29f17e9 295 Pfam PF03466 LysR substrate binding domain 90 292 2.4E-30 T 14-10-2018 IPR005119 LysR, substrate-binding D521_1579 395021ba7f4d78e72c652d52c29f17e9 295 SUPERFAMILY SSF53850 90 292 1.01E-32 T 14-10-2018 D521_1579 395021ba7f4d78e72c652d52c29f17e9 295 Gene3D G3DSA:3.40.190.290 92 295 6.2E-33 T 14-10-2018 D521_1579 395021ba7f4d78e72c652d52c29f17e9 295 Gene3D G3DSA:1.10.10.10 4 91 2.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0952 8edfc8941c945cab195327a2a8b5d3d3 233 SUPERFAMILY SSF48403 33 214 2.95E-42 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily D521_0952 8edfc8941c945cab195327a2a8b5d3d3 233 SMART SM00248 61 91 120.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 D521_0952 8edfc8941c945cab195327a2a8b5d3d3 233 SMART SM00248 95 125 26.0 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 D521_0952 8edfc8941c945cab195327a2a8b5d3d3 233 SMART SM00248 126 155 2.3E-4 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 D521_0952 8edfc8941c945cab195327a2a8b5d3d3 233 SMART SM00248 159 188 0.0052 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 D521_0952 8edfc8941c945cab195327a2a8b5d3d3 233 PRINTS PR01415 Ankyrin repeat signature 175 189 3.4E-7 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 D521_0952 8edfc8941c945cab195327a2a8b5d3d3 233 PRINTS PR01415 Ankyrin repeat signature 127 142 3.4E-7 T 14-10-2018 IPR002110 Ankyrin repeat GO:0005515 D521_0952 8edfc8941c945cab195327a2a8b5d3d3 233 Gene3D G3DSA:1.25.40.20 24 121 1.7E-16 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily D521_0952 8edfc8941c945cab195327a2a8b5d3d3 233 Pfam PF12796 Ankyrin repeats (3 copies) 107 190 1.6E-17 T 14-10-2018 IPR020683 Ankyrin repeat-containing domain D521_0952 8edfc8941c945cab195327a2a8b5d3d3 233 Gene3D G3DSA:1.25.40.20 122 215 2.6E-26 T 14-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily D521_1472 8c7103274166a4d4d5e36e660d6a21d9 342 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 2 331 49.868 T 14-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 D521_1472 8c7103274166a4d4d5e36e660d6a21d9 342 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 243 2.3E-41 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 D521_1472 8c7103274166a4d4d5e36e660d6a21d9 342 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 3 330 2.0E-135 T 14-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 D521_1472 8c7103274166a4d4d5e36e660d6a21d9 342 Gene3D G3DSA:3.40.50.720 4 325 1.8E-125 T 14-10-2018 D521_1472 8c7103274166a4d4d5e36e660d6a21d9 342 SUPERFAMILY SSF51735 1 332 4.75E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1472 8c7103274166a4d4d5e36e660d6a21d9 342 Gene3D G3DSA:3.90.25.10 169 312 1.8E-125 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 SUPERFAMILY SSF56784 469 777 1.54E-52 T 14-10-2018 IPR036412 HAD-like superfamily D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00943 Copper-transporting ATPase signature 181 200 3.3E-16 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00943 Copper-transporting ATPase signature 238 257 3.3E-16 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00943 Copper-transporting ATPase signature 647 664 3.3E-16 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00943 Copper-transporting ATPase signature 454 469 3.3E-16 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00943 Copper-transporting ATPase signature 258 276 3.3E-16 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00943 Copper-transporting ATPase signature 392 406 3.3E-16 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 196 779 2.5E-180 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 Pfam PF00702 haloacid dehalogenase-like hydrolase 467 684 4.7E-41 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 617 627 1.8E-28 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 319 333 1.8E-28 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 693 705 1.8E-28 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 670 689 1.8E-28 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 595 606 1.8E-28 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 471 485 1.8E-28 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 Gene3D G3DSA:3.40.50.1000 452 721 1.5E-86 T 14-10-2018 IPR023214 HAD superfamily D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 473 479 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 Pfam PF04945 YHS domain 29 71 5.0E-12 T 14-10-2018 IPR007029 YHS domain D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 Gene3D G3DSA:3.40.1110.10 482 602 1.5E-86 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 240 748 8.6E-88 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 177 780 2.4E-172 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 SUPERFAMILY SSF81665 236 464 6.41E-12 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 Pfam PF00122 E1-E2 ATPase 269 450 1.3E-55 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 Gene3D G3DSA:2.70.150.20 262 374 9.9E-43 T 14-10-2018 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 SUPERFAMILY SSF81653 272 369 1.57E-25 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 D521_1653 cfb8f3801f0cebdcab98e91d2c5b4606 782 SMART SM00746 30 67 1.1E-5 T 14-10-2018 IPR011017 TRASH domain D521_0709 4d946ef77de8835107abdc7fd872e818 224 Pfam PF01292 Prokaryotic cytochrome b561 21 182 1.5E-22 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 D521_0709 4d946ef77de8835107abdc7fd872e818 224 Gene3D G3DSA:1.20.950.20 11 172 7.7E-17 T 14-10-2018 D521_0709 4d946ef77de8835107abdc7fd872e818 224 SUPERFAMILY SSF81342 17 184 6.67E-33 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 D521_0847 93982cb264169a5e018cf551c38a161b 403 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 173 401 4.1E-78 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 D521_0847 93982cb264169a5e018cf551c38a161b 403 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 5 402 2.3E-168 T 14-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 D521_0847 93982cb264169a5e018cf551c38a161b 403 SUPERFAMILY SSF52777 173 402 3.6E-85 T 14-10-2018 D521_0847 93982cb264169a5e018cf551c38a161b 403 Pfam PF02817 e3 binding domain 117 150 8.1E-11 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 D521_0847 93982cb264169a5e018cf551c38a161b 403 SUPERFAMILY SSF47005 110 153 1.7E-9 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 D521_0847 93982cb264169a5e018cf551c38a161b 403 Gene3D G3DSA:4.10.320.10 117 155 4.4E-11 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 D521_0847 93982cb264169a5e018cf551c38a161b 403 Gene3D G3DSA:3.30.559.10 171 403 2.5E-92 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 D521_0847 93982cb264169a5e018cf551c38a161b 403 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 D521_0847 93982cb264169a5e018cf551c38a161b 403 SUPERFAMILY SSF51230 2 97 2.22E-26 T 14-10-2018 IPR011053 Single hybrid motif D521_0847 93982cb264169a5e018cf551c38a161b 403 Pfam PF00364 Biotin-requiring enzyme 5 77 1.5E-20 T 14-10-2018 IPR000089 Biotin/lipoyl attachment D521_0847 93982cb264169a5e018cf551c38a161b 403 Gene3D G3DSA:2.40.50.100 2 101 9.9E-24 T 14-10-2018 D521_0937 e2a55e1548666482138b088d12b624d1 253 SUPERFAMILY SSF53335 6 229 1.06E-39 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0937 e2a55e1548666482138b088d12b624d1 253 Gene3D G3DSA:3.40.50.150 7 246 3.3E-35 T 14-10-2018 D521_0937 e2a55e1548666482138b088d12b624d1 253 Pfam PF01564 Spermine/spermidine synthase domain 65 166 7.2E-8 T 14-10-2018 D521_0023 976e8cc8d60d75941084161cccaa01a4 138 SUPERFAMILY SSF46604 87 135 4.71E-12 T 14-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0023 976e8cc8d60d75941084161cccaa01a4 138 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 89 2.0E-33 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0023 976e8cc8d60d75941084161cccaa01a4 138 Gene3D G3DSA:1.20.5.440 90 132 9.5E-12 T 14-10-2018 D521_0023 976e8cc8d60d75941084161cccaa01a4 138 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 88 131 1.7E-8 T 14-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain D521_0023 976e8cc8d60d75941084161cccaa01a4 138 Gene3D G3DSA:2.60.15.10 2 89 2.9E-32 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0023 976e8cc8d60d75941084161cccaa01a4 138 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 130 21.049 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0023 976e8cc8d60d75941084161cccaa01a4 138 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 131 2.1E-43 T 14-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0023 976e8cc8d60d75941084161cccaa01a4 138 SUPERFAMILY SSF51344 3 85 2.35E-25 T 14-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0023 976e8cc8d60d75941084161cccaa01a4 138 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 83 2.7E-30 T 14-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0734 f346fc9015d9f83efed33f03d877ac92 163 SUPERFAMILY SSF55021 79 162 8.24E-25 T 14-10-2018 D521_0734 f346fc9015d9f83efed33f03d877ac92 163 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 157 5.1E-63 T 14-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 D521_0734 f346fc9015d9f83efed33f03d877ac92 163 SUPERFAMILY SSF55021 1 76 2.7E-22 T 14-10-2018 D521_0734 f346fc9015d9f83efed33f03d877ac92 163 Pfam PF10369 Small subunit of acetolactate synthase 84 157 4.6E-25 T 14-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 D521_0734 f346fc9015d9f83efed33f03d877ac92 163 Gene3D G3DSA:3.30.70.1150 83 163 3.2E-28 T 14-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal D521_0734 f346fc9015d9f83efed33f03d877ac92 163 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 9.0E-34 T 14-10-2018 D521_0734 f346fc9015d9f83efed33f03d877ac92 163 Gene3D G3DSA:3.30.70.260 1 78 9.1E-35 T 14-10-2018 D521_0734 f346fc9015d9f83efed33f03d877ac92 163 Pfam PF01842 ACT domain 3 68 2.2E-14 T 14-10-2018 IPR002912 ACT domain D521_0311 ef7af7463713f4a6a69df672345fceab 281 Gene3D G3DSA:3.90.550.10 1 196 2.4E-13 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0311 ef7af7463713f4a6a69df672345fceab 281 Pfam PF00535 Glycosyl transferase family 2 3 90 1.9E-7 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 D521_0311 ef7af7463713f4a6a69df672345fceab 281 SUPERFAMILY SSF53448 2 188 2.25E-18 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0237 b8595db20d8edf713b571b7bb0a8ed66 353 Gene3D G3DSA:3.40.50.300 1 151 1.4E-42 T 14-10-2018 D521_0237 b8595db20d8edf713b571b7bb0a8ed66 353 SUPERFAMILY SSF52540 17 226 9.56E-35 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0237 b8595db20d8edf713b571b7bb0a8ed66 353 Pfam PF06144 DNA polymerase III, delta subunit 24 205 5.3E-23 T 14-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 D521_0237 b8595db20d8edf713b571b7bb0a8ed66 353 Gene3D G3DSA:1.20.272.10 230 352 8.5E-25 T 14-10-2018 D521_0237 b8595db20d8edf713b571b7bb0a8ed66 353 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 20 345 3.4E-75 T 14-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 D521_0237 b8595db20d8edf713b571b7bb0a8ed66 353 Gene3D G3DSA:1.10.8.60 154 229 3.7E-24 T 14-10-2018 D521_0237 b8595db20d8edf713b571b7bb0a8ed66 353 Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term 231 323 1.2E-6 T 14-10-2018 IPR032780 DNA polymerase III subunit delta, C-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_0237 b8595db20d8edf713b571b7bb0a8ed66 353 SUPERFAMILY SSF48019 228 347 6.46E-24 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 D521_0241 07076126f819871af0473b2f3b361657 50 ProSitePatterns PS00202 Rubredoxin signature. 29 39 - T 14-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 D521_0241 07076126f819871af0473b2f3b361657 50 Gene3D G3DSA:2.20.28.10 1 50 1.7E-25 T 14-10-2018 D521_0241 07076126f819871af0473b2f3b361657 50 PIRSF PIRSF000071 1 50 3.0E-24 T 14-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 D521_0241 07076126f819871af0473b2f3b361657 50 SUPERFAMILY SSF57802 1 48 1.11E-20 T 14-10-2018 D521_0241 07076126f819871af0473b2f3b361657 50 Pfam PF00301 Rubredoxin 1 45 1.6E-21 T 14-10-2018 IPR024935 Rubredoxin domain GO:0005506 D521_0777 6d1a3c326956299282cb9fa3df2cc211 627 Gene3D G3DSA:3.40.50.12780 36 494 5.3E-97 T 14-10-2018 D521_0777 6d1a3c326956299282cb9fa3df2cc211 627 SUPERFAMILY SSF56801 3 617 6.93E-159 T 14-10-2018 D521_0777 6d1a3c326956299282cb9fa3df2cc211 627 ProSitePatterns PS00455 Putative AMP-binding domain signature. 237 248 - T 14-10-2018 IPR020845 AMP-binding, conserved site D521_0777 6d1a3c326956299282cb9fa3df2cc211 627 TIGRFAM TIGR02316 propion_prpE: propionate--CoA ligase 1 622 0.0 T 14-10-2018 IPR012694 Propionate--CoA ligase GO:0019629|GO:0050218 KEGG: 00640+6.2.1.17|MetaCyc: PWY-3941|MetaCyc: PWY-5104|MetaCyc: PWY-5747 D521_0777 6d1a3c326956299282cb9fa3df2cc211 627 Gene3D G3DSA:3.30.300.30 497 625 4.6E-27 T 14-10-2018 D521_0777 6d1a3c326956299282cb9fa3df2cc211 627 Pfam PF13193 AMP-binding enzyme C-terminal domain 510 587 3.7E-23 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain D521_0777 6d1a3c326956299282cb9fa3df2cc211 627 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 3 57 1.3E-23 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 D521_0777 6d1a3c326956299282cb9fa3df2cc211 627 Pfam PF00501 AMP-binding enzyme 59 501 1.4E-83 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 D521_0526 8df9537a651a06b3f20f8675458ccce2 190 SUPERFAMILY SSF55068 9 177 7.85E-70 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 D521_0526 8df9537a651a06b3f20f8675458ccce2 190 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 12 171 36.072 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 D521_0526 8df9537a651a06b3f20f8675458ccce2 190 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 13 166 5.3E-57 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 D521_0526 8df9537a651a06b3f20f8675458ccce2 190 Gene3D G3DSA:3.30.1060.10 1 176 5.4E-67 T 14-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 D521_0526 8df9537a651a06b3f20f8675458ccce2 190 Pfam PF01625 Peptide methionine sulfoxide reductase 15 166 2.4E-60 T 14-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 D521_0755 f3973398ac7a164cc5dfb5dec1e3d9e9 215 Gene3D G3DSA:1.20.120.1200 9 172 2.7E-43 T 14-10-2018 D521_0755 f3973398ac7a164cc5dfb5dec1e3d9e9 215 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 23 170 3.7E-36 T 14-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 Pfam PF00717 Peptidase S24-like 66 148 4.7E-22 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 Gene3D G3DSA:2.10.109.10 58 257 1.5E-72 T 14-10-2018 D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 46 256 2.6E-52 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 ProSitePatterns PS00760 Signal peptidases I lysine active site. 126 138 - T 14-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 Pfam PF10502 Signal peptidase, peptidase S26 217 255 4.8E-6 T 14-10-2018 IPR019533 Peptidase S26 D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 ProSitePatterns PS00501 Signal peptidases I serine active site. 69 76 - T 14-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 Gene3D G3DSA:2.170.230.10 135 217 1.5E-72 T 14-10-2018 D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 SUPERFAMILY SSF51306 58 264 2.88E-67 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 124 136 2.5E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 218 237 2.5E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 D521_1421 f282ff40d568ec1235fe0a243a9a8d67 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 60 76 2.5E-24 T 14-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 D521_1521 637cb8af5fd48bef6262bbaf0c58dfcf 252 SUPERFAMILY SSF51206 16 155 1.31E-28 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like D521_1521 637cb8af5fd48bef6262bbaf0c58dfcf 252 SMART SM00419 180 228 6.9E-14 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 D521_1521 637cb8af5fd48bef6262bbaf0c58dfcf 252 SMART SM00100 23 141 1.4E-15 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain D521_1521 637cb8af5fd48bef6262bbaf0c58dfcf 252 Pfam PF13545 Crp-like helix-turn-helix domain 161 234 8.7E-19 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 D521_1521 637cb8af5fd48bef6262bbaf0c58dfcf 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 202 217 3.2E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 D521_1521 637cb8af5fd48bef6262bbaf0c58dfcf 252 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 186 202 3.2E-10 T 14-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 D521_1521 637cb8af5fd48bef6262bbaf0c58dfcf 252 Pfam PF00027 Cyclic nucleotide-binding domain 43 128 8.8E-15 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain D521_1521 637cb8af5fd48bef6262bbaf0c58dfcf 252 Gene3D G3DSA:2.60.120.10 36 156 2.0E-39 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_1521 637cb8af5fd48bef6262bbaf0c58dfcf 252 SUPERFAMILY SSF46785 159 238 3.57E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1521 637cb8af5fd48bef6262bbaf0c58dfcf 252 Gene3D G3DSA:1.10.10.10 158 238 7.7E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0447 efe7e8c29ffd99869868d84b363b27ff 495 Pfam PF05658 Head domain of trimeric autotransporter adhesin 96 122 7.9E-8 T 14-10-2018 IPR008640 Head domain of trimeric autotransporter adhesin GO:0009405|GO:0019867 D521_0447 efe7e8c29ffd99869868d84b363b27ff 495 Pfam PF03895 YadA-like membrane anchor domain 440 495 4.6E-10 T 14-10-2018 IPR005594 YadA-like, C-terminal D521_0447 efe7e8c29ffd99869868d84b363b27ff 495 SUPERFAMILY SSF101967 128 247 2.35E-24 T 14-10-2018 D521_0447 efe7e8c29ffd99869868d84b363b27ff 495 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 226 255 1.1E-7 T 14-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 D521_0447 efe7e8c29ffd99869868d84b363b27ff 495 Pfam PF05662 Coiled stalk of trimeric autotransporter adhesin 375 413 3.8E-4 T 14-10-2018 IPR008635 Coiled stalk of trimeric autotransporter adhesin GO:0009405|GO:0019867 D521_0447 efe7e8c29ffd99869868d84b363b27ff 495 SUPERFAMILY SSF101967 22 139 1.83E-18 T 14-10-2018 D521_0447 efe7e8c29ffd99869868d84b363b27ff 495 Gene3D G3DSA:2.150.10.10 14 111 1.8E-14 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal D521_0447 efe7e8c29ffd99869868d84b363b27ff 495 Gene3D G3DSA:3.30.1300.30 387 495 1.6E-16 T 14-10-2018 D521_0447 efe7e8c29ffd99869868d84b363b27ff 495 SUPERFAMILY SSF54523 386 495 4.39E-16 T 14-10-2018 D521_0447 efe7e8c29ffd99869868d84b363b27ff 495 Gene3D G3DSA:2.150.10.10 112 254 8.1E-36 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal D521_1013 b89f06756e0ab7da7da744a82d8c8bc1 245 Gene3D G3DSA:1.10.10.10 10 78 3.9E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1013 b89f06756e0ab7da7da744a82d8c8bc1 245 Pfam PF07702 UTRA domain 98 235 6.0E-34 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 D521_1013 b89f06756e0ab7da7da744a82d8c8bc1 245 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 2.4E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1013 b89f06756e0ab7da7da744a82d8c8bc1 245 SUPERFAMILY SSF64288 66 241 1.57E-37 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily D521_1013 b89f06756e0ab7da7da744a82d8c8bc1 245 SMART SM00345 18 77 5.9E-21 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1013 b89f06756e0ab7da7da744a82d8c8bc1 245 SMART SM00866 97 239 2.4E-31 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 D521_1013 b89f06756e0ab7da7da744a82d8c8bc1 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 1.1E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1013 b89f06756e0ab7da7da744a82d8c8bc1 245 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 1.1E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1013 b89f06756e0ab7da7da744a82d8c8bc1 245 Gene3D G3DSA:3.40.1410.10 85 244 7.4E-48 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily D521_1013 b89f06756e0ab7da7da744a82d8c8bc1 245 SUPERFAMILY SSF46785 12 90 3.16E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1650 53de18b6802bb40d716e2cc2105796b0 208 Gene3D G3DSA:2.150.10.10 98 208 4.4E-5 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal D521_1650 53de18b6802bb40d716e2cc2105796b0 208 SUPERFAMILY SSF51120 104 190 3.66E-6 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal D521_1596 53de18b6802bb40d716e2cc2105796b0 208 Gene3D G3DSA:2.150.10.10 98 208 4.4E-5 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal D521_1596 53de18b6802bb40d716e2cc2105796b0 208 SUPERFAMILY SSF51120 104 190 3.66E-6 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal D521_1042 5fd1ac3601b170762ab490127a6865a0 483 Gene3D G3DSA:3.40.50.300 126 310 5.8E-62 T 14-10-2018 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 226 241 - T 14-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 SMART SM00448 2 113 6.5E-27 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 353 362 - T 14-10-2018 IPR025944 Sigma-54 interaction domain, conserved site D521_1042 5fd1ac3601b170762ab490127a6865a0 483 SMART SM00382 160 303 7.6E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1042 5fd1ac3601b170762ab490127a6865a0 483 Gene3D G3DSA:1.10.8.60 311 389 2.6E-17 T 14-10-2018 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 SUPERFAMILY SSF46689 410 482 1.33E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 4 479 6.6E-199 T 14-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 SUPERFAMILY SSF52540 139 382 2.0E-68 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1042 5fd1ac3601b170762ab490127a6865a0 483 Gene3D G3DSA:1.10.10.60 396 482 5.4E-18 T 14-10-2018 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 SUPERFAMILY SSF52172 2 185 3.42E-39 T 14-10-2018 IPR011006 CheY-like superfamily D521_1042 5fd1ac3601b170762ab490127a6865a0 483 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 164 177 - T 14-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 Gene3D G3DSA:3.40.50.2300 1 122 1.3E-34 T 14-10-2018 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 Pfam PF02954 Bacterial regulatory protein, Fis family 441 479 7.9E-13 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 Pfam PF00158 Sigma-54 interaction domain 140 306 1.2E-64 T 14-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 Pfam PF00072 Response regulator receiver domain 4 113 6.8E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 445 462 5.6E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 D521_1042 5fd1ac3601b170762ab490127a6865a0 483 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 462 482 5.6E-10 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 D521_0613 b1a892e07ab472feb2dd19d51cc578b4 303 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 5 218 4.2E-75 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0613 b1a892e07ab472feb2dd19d51cc578b4 303 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 241 299 6.0E-15 T 14-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0613 b1a892e07ab472feb2dd19d51cc578b4 303 Gene3D G3DSA:3.30.2350.10 1 248 3.6E-90 T 14-10-2018 D521_0613 b1a892e07ab472feb2dd19d51cc578b4 303 SUPERFAMILY SSF88697 240 300 2.78E-5 T 14-10-2018 IPR015947 PUA-like superfamily D521_0613 b1a892e07ab472feb2dd19d51cc578b4 303 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 181 237 8.2E-14 T 14-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 D521_0613 b1a892e07ab472feb2dd19d51cc578b4 303 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 5 299 18.822 T 14-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0613 b1a892e07ab472feb2dd19d51cc578b4 303 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 27 180 1.5E-56 T 14-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 D521_0613 b1a892e07ab472feb2dd19d51cc578b4 303 SUPERFAMILY SSF55120 5 224 1.09E-77 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1749 ceee757a7d551d0f2871bc04be1e1a44 271 SUPERFAMILY SSF51621 10 269 1.73E-104 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 D521_1749 ceee757a7d551d0f2871bc04be1e1a44 271 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 10 269 41.323 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 D521_1749 ceee757a7d551d0f2871bc04be1e1a44 271 Pfam PF02548 Ketopantoate hydroxymethyltransferase 10 264 1.8E-106 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 D521_1749 ceee757a7d551d0f2871bc04be1e1a44 271 PIRSF PIRSF000388 2 270 3.3E-100 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 D521_1749 ceee757a7d551d0f2871bc04be1e1a44 271 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 13 269 5.1E-100 T 14-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 D521_1749 ceee757a7d551d0f2871bc04be1e1a44 271 Gene3D G3DSA:3.20.20.60 3 269 1.0E-106 T 14-10-2018 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 297 3.9E-125 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 161 190 - T 14-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 SUPERFAMILY SSF52210 132 296 1.31E-53 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 SMART SM00881 4 103 1.2E-26 T 14-10-2018 IPR003781 CoA-binding GO:0048037 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 Gene3D G3DSA:3.40.50.261 133 297 3.2E-66 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 9.1E-33 T 14-10-2018 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 PRINTS PR01798 Succinyl-CoA synthase signature 186 204 9.1E-33 T 14-10-2018 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 PRINTS PR01798 Succinyl-CoA synthase signature 249 266 9.1E-33 T 14-10-2018 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 PRINTS PR01798 Succinyl-CoA synthase signature 217 230 9.1E-33 T 14-10-2018 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 Pfam PF00549 CoA-ligase 160 271 1.2E-15 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 Pfam PF02629 CoA binding domain 6 102 1.0E-21 T 14-10-2018 IPR003781 CoA-binding GO:0048037 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 245 258 - T 14-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 Gene3D G3DSA:3.40.50.720 2 132 7.7E-41 T 14-10-2018 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 PIRSF PIRSF001553 1 297 7.7E-115 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 SUPERFAMILY SSF51735 1 114 1.11E-33 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1827 2d335ae7ffe6440ebae201ceb32235f3 297 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 297 39.867 T 14-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 SMART SM00279 175 210 3.6E-8 T 14-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 SUPERFAMILY SSF56672 541 947 3.45E-155 T 14-10-2018 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 SMART SM00474 352 536 5.1E-35 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 PRINTS PR00868 DNA-polymerase family A (pol I) signature 864 880 4.9E-78 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 PRINTS PR00868 DNA-polymerase family A (pol I) signature 894 907 4.9E-78 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 PRINTS PR00868 DNA-polymerase family A (pol I) signature 749 762 4.9E-78 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 PRINTS PR00868 DNA-polymerase family A (pol I) signature 697 712 4.9E-78 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 PRINTS PR00868 DNA-polymerase family A (pol I) signature 773 798 4.9E-78 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 PRINTS PR00868 DNA-polymerase family A (pol I) signature 719 742 4.9E-78 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 PRINTS PR00868 DNA-polymerase family A (pol I) signature 832 843 4.9E-78 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 PRINTS PR00868 DNA-polymerase family A (pol I) signature 674 696 4.9E-78 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 PRINTS PR00868 DNA-polymerase family A (pol I) signature 810 821 4.9E-78 T 14-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 Pfam PF01612 3'-5' exonuclease 352 536 1.5E-37 T 14-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 Gene3D G3DSA:3.30.420.10 349 561 9.0E-67 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 SUPERFAMILY SSF47807 173 290 1.21E-29 T 14-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 TIGRFAM TIGR00593 pola: DNA polymerase I 11 947 1.1E-279 T 14-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 SMART SM00475 8 266 2.5E-112 T 14-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 10 172 2.1E-53 T 14-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 Gene3D G3DSA:1.10.150.20 728 871 6.0E-109 T 14-10-2018 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 Gene3D G3DSA:1.10.150.20 176 248 5.6E-88 T 14-10-2018 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 Pfam PF00476 DNA polymerase family A 571 945 1.7E-151 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 Gene3D G3DSA:3.30.70.370 683 943 6.0E-109 T 14-10-2018 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 Gene3D G3DSA:3.40.50.1010 11 282 5.6E-88 T 14-10-2018 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 SUPERFAMILY SSF88723 8 172 1.88E-55 T 14-10-2018 IPR029060 PIN-like domain superfamily D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 173 256 5.1E-23 T 14-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 SMART SM00482 705 911 3.3E-117 T 14-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 SUPERFAMILY SSF53098 355 536 2.14E-53 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 Gene3D G3DSA:1.20.1060.10 562 677 1.5E-41 T 14-10-2018 D521_1700 86015bbf4cc2c3bad2e94c66d80fcdf3 947 ProSitePatterns PS00447 DNA polymerase family A signature. 773 792 - T 14-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_0511 f1e7c077d840099d3607cad7105d3501 283 SUPERFAMILY SSF52374 1 283 4.69E-93 T 14-10-2018 D521_0511 f1e7c077d840099d3607cad7105d3501 283 Hamap MF_00158 Pantothenate synthetase [panC]. 2 283 37.173 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 D521_0511 f1e7c077d840099d3607cad7105d3501 283 Gene3D G3DSA:3.40.50.620 2 174 1.2E-71 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0511 f1e7c077d840099d3607cad7105d3501 283 Gene3D G3DSA:3.30.1300.10 175 281 1.3E-28 T 14-10-2018 D521_0511 f1e7c077d840099d3607cad7105d3501 283 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 282 2.6E-86 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 D521_0511 f1e7c077d840099d3607cad7105d3501 283 Pfam PF02569 Pantoate-beta-alanine ligase 3 281 1.0E-93 T 14-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 D521_0511 f1e7c077d840099d3607cad7105d3501 283 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 19 83 4.7E-9 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 D521_0298 78dbb15c552a2c7e19e8d84c80986739 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 130 10.41 T 14-10-2018 IPR022907 VapC family GO:0004540 D521_0298 78dbb15c552a2c7e19e8d84c80986739 134 SMART SM00670 2 121 5.2E-8 T 14-10-2018 IPR002716 PIN domain D521_0298 78dbb15c552a2c7e19e8d84c80986739 134 Pfam PF01850 PIN domain 4 125 2.0E-18 T 14-10-2018 IPR002716 PIN domain D521_0298 78dbb15c552a2c7e19e8d84c80986739 134 SUPERFAMILY SSF88723 1 132 1.4E-39 T 14-10-2018 IPR029060 PIN-like domain superfamily D521_0298 78dbb15c552a2c7e19e8d84c80986739 134 Gene3D G3DSA:3.40.50.1010 1 132 1.6E-43 T 14-10-2018 D521_1158 e0d6098a6fadc2c0310ebad43f8ee9ef 366 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 345 5.4E-93 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 D521_1158 e0d6098a6fadc2c0310ebad43f8ee9ef 366 SUPERFAMILY SSF51395 5 366 1.34E-119 T 14-10-2018 D521_1158 e0d6098a6fadc2c0310ebad43f8ee9ef 366 Gene3D G3DSA:3.20.20.70 2 366 8.8E-142 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0488 191ae01caa4a345d57eab1e8673e75dd 239 SUPERFAMILY SSF75625 3 238 1.44E-95 T 14-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0488 191ae01caa4a345d57eab1e8673e75dd 239 Gene3D G3DSA:1.10.10.200 1 81 3.6E-35 T 14-10-2018 IPR017856 Integrase-like, N-terminal D521_0488 191ae01caa4a345d57eab1e8673e75dd 239 Gene3D G3DSA:3.30.70.980 130 205 2.9E-52 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0488 191ae01caa4a345d57eab1e8673e75dd 239 Pfam PF01709 Transcriptional regulator 5 237 2.7E-93 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0488 191ae01caa4a345d57eab1e8673e75dd 239 Gene3D G3DSA:3.30.70.980 86 236 2.9E-52 T 14-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0488 191ae01caa4a345d57eab1e8673e75dd 239 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 34.928 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0488 191ae01caa4a345d57eab1e8673e75dd 239 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 1.8E-94 T 14-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1919 c6f55f3aeb271c1c7b1b8872dcf9cc66 198 Gene3D G3DSA:3.40.50.1470 1 198 1.9E-68 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 D521_1919 c6f55f3aeb271c1c7b1b8872dcf9cc66 198 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 187 34.435 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 D521_1919 c6f55f3aeb271c1c7b1b8872dcf9cc66 198 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 109 119 - T 14-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 D521_1919 c6f55f3aeb271c1c7b1b8872dcf9cc66 198 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 194 1.6E-55 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 D521_1919 c6f55f3aeb271c1c7b1b8872dcf9cc66 198 SUPERFAMILY SSF53178 2 194 3.53E-63 T 14-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 D521_1919 c6f55f3aeb271c1c7b1b8872dcf9cc66 198 Pfam PF01195 Peptidyl-tRNA hydrolase 4 192 4.0E-53 T 14-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 D521_0423 e1e0c7ff0af14de9656fe09a0b79a701 420 SUPERFAMILY SSF103473 6 403 1.57E-61 T 14-10-2018 IPR036259 MFS transporter superfamily D521_0423 e1e0c7ff0af14de9656fe09a0b79a701 420 Gene3D G3DSA:1.20.1250.20 194 414 6.2E-56 T 14-10-2018 D521_0423 e1e0c7ff0af14de9656fe09a0b79a701 420 Pfam PF07690 Major Facilitator Superfamily 20 369 4.8E-40 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_0423 e1e0c7ff0af14de9656fe09a0b79a701 420 Gene3D G3DSA:1.20.1250.20 3 188 9.1E-49 T 14-10-2018 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 2.6E-16 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.532 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 8.9E-75 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 SUPERFAMILY SSF50615 10 94 2.55E-29 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 SUPERFAMILY SSF52540 96 381 3.75E-95 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0020 a47bde9894491063b803f8dc9d0a012f 513 SUPERFAMILY SSF47917 383 510 5.49E-46 T 14-10-2018 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 Gene3D G3DSA:2.40.30.20 1 93 4.0E-34 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 506 8.7E-45 T 14-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 Gene3D G3DSA:1.20.150.20 383 513 3.0E-46 T 14-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 PIRSF PIRSF039088 1 513 6.4E-239 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 Gene3D G3DSA:3.40.50.300 94 382 1.1E-130 T 14-10-2018 D521_0020 a47bde9894491063b803f8dc9d0a012f 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 510 1.9E-249 T 14-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0043 24b8534b0e4c93e158abce9eb7ded3f3 124 SUPERFAMILY SSF48300 3 60 4.32E-16 T 14-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0043 24b8534b0e4c93e158abce9eb7ded3f3 124 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 124 24.199 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0043 24b8534b0e4c93e158abce9eb7ded3f3 124 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 60 98 3.0E-13 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0043 24b8534b0e4c93e158abce9eb7ded3f3 124 Gene3D G3DSA:3.30.1390.10 54 124 2.5E-29 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like D521_0043 24b8534b0e4c93e158abce9eb7ded3f3 124 SUPERFAMILY SSF54736 53 124 2.62E-23 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like D521_0043 24b8534b0e4c93e158abce9eb7ded3f3 124 Gene3D G3DSA:1.20.5.710 2 53 7.4E-22 T 14-10-2018 D521_0043 24b8534b0e4c93e158abce9eb7ded3f3 124 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 124 5.9E-48 T 14-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0043 24b8534b0e4c93e158abce9eb7ded3f3 124 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 4 51 1.3E-18 T 14-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0043 24b8534b0e4c93e158abce9eb7ded3f3 124 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 58 124 2.4E-29 T 14-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0862 a29fc8c6083a1cfc1e39b70abe2d1133 166 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 38 55 - T 14-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 D521_0862 a29fc8c6083a1cfc1e39b70abe2d1133 166 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 17 32 5.1E-12 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 D521_0862 a29fc8c6083a1cfc1e39b70abe2d1133 166 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 43 55 5.1E-12 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 D521_0862 a29fc8c6083a1cfc1e39b70abe2d1133 166 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 120 135 5.1E-12 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 D521_0862 a29fc8c6083a1cfc1e39b70abe2d1133 166 Gene3D G3DSA:2.40.100.10 1 165 3.6E-70 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily D521_0862 a29fc8c6083a1cfc1e39b70abe2d1133 166 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 4 163 1.5E-48 T 14-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 D521_0862 a29fc8c6083a1cfc1e39b70abe2d1133 166 PIRSF PIRSF001467 1 166 7.3E-30 T 14-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 D521_0862 a29fc8c6083a1cfc1e39b70abe2d1133 166 SUPERFAMILY SSF50891 3 165 3.36E-60 T 14-10-2018 IPR029000 Cyclophilin-like domain superfamily D521_1993 243da61c060760e0a778798348c0d26e 610 SUPERFAMILY SSF53697 249 610 1.02E-107 T 14-10-2018 D521_1993 243da61c060760e0a778798348c0d26e 610 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 610 2.3E-241 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 D521_1993 243da61c060760e0a778798348c0d26e 610 SUPERFAMILY SSF56235 2 237 1.12E-65 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_1993 243da61c060760e0a778798348c0d26e 610 Pfam PF01380 SIS domain 463 590 6.7E-26 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 D521_1993 243da61c060760e0a778798348c0d26e 610 Pfam PF01380 SIS domain 294 418 2.2E-26 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 D521_1993 243da61c060760e0a778798348c0d26e 610 Gene3D G3DSA:3.40.50.10490 253 609 1.0E-139 T 14-10-2018 D521_1993 243da61c060760e0a778798348c0d26e 610 Pfam PF13522 Glutamine amidotransferase domain 65 195 1.1E-21 T 14-10-2018 D521_1993 243da61c060760e0a778798348c0d26e 610 Gene3D G3DSA:3.60.20.10 2 244 1.8E-70 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_1993 243da61c060760e0a778798348c0d26e 610 Gene3D G3DSA:3.40.50.10490 448 595 1.0E-139 T 14-10-2018 D521_1993 243da61c060760e0a778798348c0d26e 610 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 610 38.618 T 14-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 D521_1052 05794981da516e0e78b179d09903f4c8 90 PIRSF PIRSF029827 1 90 5.6E-41 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 D521_1052 05794981da516e0e78b179d09903f4c8 90 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 28.202 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 D521_1052 05794981da516e0e78b179d09903f4c8 90 SUPERFAMILY SSF111148 1 89 8.63E-39 T 14-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 D521_1052 05794981da516e0e78b179d09903f4c8 90 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 2.6E-43 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 D521_1052 05794981da516e0e78b179d09903f4c8 90 Gene3D G3DSA:1.10.3880.10 1 90 6.4E-40 T 14-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 D521_1052 05794981da516e0e78b179d09903f4c8 90 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 75 2.0E-34 T 14-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 D521_0056 ba1a689ae5552b2f6c6f27441a0916e9 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 14-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0056 ba1a689ae5552b2f6c6f27441a0916e9 92 SUPERFAMILY SSF54570 3 84 1.7E-34 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0056 ba1a689ae5552b2f6c6f27441a0916e9 92 Pfam PF00203 Ribosomal protein S19 3 83 1.7E-36 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0056 ba1a689ae5552b2f6c6f27441a0916e9 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 8.1E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0056 ba1a689ae5552b2f6c6f27441a0916e9 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 8.1E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0056 ba1a689ae5552b2f6c6f27441a0916e9 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 8.1E-24 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0056 ba1a689ae5552b2f6c6f27441a0916e9 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 90 7.0E-44 T 14-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 D521_0056 ba1a689ae5552b2f6c6f27441a0916e9 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.188 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0056 ba1a689ae5552b2f6c6f27441a0916e9 92 PIRSF PIRSF002144 1 92 6.7E-34 T 14-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0056 ba1a689ae5552b2f6c6f27441a0916e9 92 Gene3D G3DSA:3.30.860.10 1 92 5.1E-41 T 14-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_2005 81d9081f01c438fd545486c10afe867e 388 Gene3D G3DSA:3.30.300.10 103 378 1.3E-178 T 14-10-2018 D521_2005 81d9081f01c438fd545486c10afe867e 388 SUPERFAMILY SSF55973 236 386 8.63E-70 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_2005 81d9081f01c438fd545486c10afe867e 388 PIRSF PIRSF000497 1 387 2.9E-172 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_2005 81d9081f01c438fd545486c10afe867e 388 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 236 375 2.5E-69 T 14-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_2005 81d9081f01c438fd545486c10afe867e 388 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 385 1.3E-184 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_2005 81d9081f01c438fd545486c10afe867e 388 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 119 129 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_2005 81d9081f01c438fd545486c10afe867e 388 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 2.4E-40 T 14-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_2005 81d9081f01c438fd545486c10afe867e 388 Pfam PF02772 S-adenosylmethionine synthetase, central domain 117 234 1.5E-45 T 14-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_2005 81d9081f01c438fd545486c10afe867e 388 Gene3D G3DSA:3.30.300.10 7 236 1.3E-178 T 14-10-2018 D521_2005 81d9081f01c438fd545486c10afe867e 388 SUPERFAMILY SSF55973 4 110 1.61E-45 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_2005 81d9081f01c438fd545486c10afe867e 388 SUPERFAMILY SSF55973 114 235 6.67E-51 T 14-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_2005 81d9081f01c438fd545486c10afe867e 388 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 262 270 - T 14-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_2005 81d9081f01c438fd545486c10afe867e 388 Gene3D G3DSA:3.30.300.10 12 273 1.3E-178 T 14-10-2018 D521_2005 81d9081f01c438fd545486c10afe867e 388 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 386 57.032 T 14-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 276 354 1.0E-7 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 PRINTS PR00606 Class ID cytochrome C signature 334 344 1.1E-18 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 PRINTS PR00606 Class ID cytochrome C signature 296 309 1.1E-18 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 PRINTS PR00606 Class ID cytochrome C signature 281 294 1.1E-18 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 PRINTS PR00606 Class ID cytochrome C signature 319 332 1.1E-18 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 PRINTS PR00606 Class ID cytochrome C signature 346 356 1.1E-18 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 Gene3D G3DSA:1.10.760.10 279 357 5.6E-26 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 SUPERFAMILY SSF46626 280 356 3.6E-17 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 SUPERFAMILY SSF46626 44 190 7.76E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 Gene3D G3DSA:1.10.760.10 41 188 2.3E-52 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0984 5c1c9e59e63ba1550f0783a9a82d5f6d 359 Pfam PF00034 Cytochrome c 66 162 2.1E-5 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 Gene3D G3DSA:3.40.50.300 588 820 2.9E-82 T 14-10-2018 D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 SUPERFAMILY SSF52540 591 807 1.59E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 SUPERFAMILY SSF55608 442 528 4.08E-16 T 14-10-2018 IPR027434 Homing endonuclease D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 29 817 6.5E-163 T 14-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 SUPERFAMILY SSF52540 203 238 4.91E-5 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 Gene3D G3DSA:3.40.50.300 183 240 5.8E-11 T 14-10-2018 D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 Gene3D G3DSA:1.10.860.10 22 182 5.3E-47 T 14-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 Pfam PF00772 DnaB-like helicase N terminal domain 29 129 2.1E-30 T 14-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 SUPERFAMILY SSF51294 241 590 1.31E-12 T 14-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 Pfam PF03796 DnaB-like helicase C terminal domain 207 239 9.3E-11 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 SUPERFAMILY SSF48024 27 138 9.55E-33 T 14-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 Pfam PF03796 DnaB-like helicase C terminal domain 590 815 4.7E-93 T 14-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 D521_1398 d695d586a251a8de7c37d3cd63ad576c 831 Gene3D G3DSA:3.10.28.10 345 552 1.7E-40 T 14-10-2018 IPR027434 Homing endonuclease D521_1359 1a41151c8c15a06b06ed1df3026ff6b0 319 Pfam PF00534 Glycosyl transferases group 1 139 292 1.7E-17 T 14-10-2018 IPR001296 Glycosyl transferase, family 1 D521_1359 1a41151c8c15a06b06ed1df3026ff6b0 319 Gene3D G3DSA:3.40.50.2000 31 129 1.5E-22 T 14-10-2018 D521_1359 1a41151c8c15a06b06ed1df3026ff6b0 319 TIGRFAM TIGR04348 TIGR04348: putative glycosyltransferase, TIGR04348 family 5 314 8.8E-111 T 14-10-2018 IPR027627 Putative glycosyltransferase D521_1359 1a41151c8c15a06b06ed1df3026ff6b0 319 Gene3D G3DSA:3.40.50.2000 130 294 1.5E-22 T 14-10-2018 D521_1359 1a41151c8c15a06b06ed1df3026ff6b0 319 SUPERFAMILY SSF53756 20 296 3.77E-29 T 14-10-2018 D521_1454 044ba241b5a19924c84279a00b42be1b 245 SUPERFAMILY SSF55811 84 236 2.57E-35 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 D521_1454 044ba241b5a19924c84279a00b42be1b 245 Pfam PF00293 NUDIX domain 85 168 1.7E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 D521_1454 044ba241b5a19924c84279a00b42be1b 245 Gene3D G3DSA:3.90.79.10 54 241 1.2E-50 T 14-10-2018 D521_0193 246556fd17b0087447aeaf4fd852d3bd 255 Pfam PF10370 Domain of unknown function (DUF2437) 4 48 1.2E-9 T 14-10-2018 IPR018833 Domain of unknown function DUF2437 D521_0193 246556fd17b0087447aeaf4fd852d3bd 255 Gene3D G3DSA:3.90.850.10 43 254 1.2E-57 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 D521_0193 246556fd17b0087447aeaf4fd852d3bd 255 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 61 253 2.7E-46 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 D521_0193 246556fd17b0087447aeaf4fd852d3bd 255 SUPERFAMILY SSF56529 50 254 4.32E-55 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 D521_1857 81e793e8fd8959356bce43ad4605b152 294 Gene3D G3DSA:1.20.58.180 206 287 1.6E-35 T 14-10-2018 D521_1857 81e793e8fd8959356bce43ad4605b152 294 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 2 282 60.094 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1857 81e793e8fd8959356bce43ad4605b152 294 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 3 289 6.7E-158 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1857 81e793e8fd8959356bce43ad4605b152 294 Gene3D G3DSA:3.30.930.10 1 205 6.1E-110 T 14-10-2018 D521_1857 81e793e8fd8959356bce43ad4605b152 294 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 4 281 1.5E-149 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1857 81e793e8fd8959356bce43ad4605b152 294 SUPERFAMILY SSF55681 3 281 1.01E-130 T 14-10-2018 D521_1857 81e793e8fd8959356bce43ad4605b152 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 108 132 3.2E-68 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1857 81e793e8fd8959356bce43ad4605b152 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 134 154 3.2E-68 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1857 81e793e8fd8959356bce43ad4605b152 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 157 172 3.2E-68 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1857 81e793e8fd8959356bce43ad4605b152 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 242 258 3.2E-68 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1857 81e793e8fd8959356bce43ad4605b152 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 56 71 3.2E-68 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1857 81e793e8fd8959356bce43ad4605b152 294 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 77 97 3.2E-68 T 14-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1995 b3f45675d1ab5c635b4baa33f1157fdd 302 Pfam PF01171 PP-loop family 37 198 3.2E-15 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 D521_1995 b3f45675d1ab5c635b4baa33f1157fdd 302 PIRSF PIRSF004976 1 275 1.3E-71 T 14-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 D521_1995 b3f45675d1ab5c635b4baa33f1157fdd 302 Gene3D G3DSA:3.40.50.620 2 279 1.3E-47 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1995 b3f45675d1ab5c635b4baa33f1157fdd 302 SUPERFAMILY SSF52402 13 232 4.82E-55 T 14-10-2018 D521_1995 b3f45675d1ab5c635b4baa33f1157fdd 302 Hamap MF_01850 tRNA-cytidine(32) 2-sulfurtransferase [ttcA]. 6 267 56.135 T 14-10-2018 IPR012089 tRNA-cytidine(32) 2-sulfurtransferase GO:0008033 D521_1942 940d2689cf490e81c471a43dd6166534 340 PIRSF PIRSF000114 1 340 4.1E-93 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 D521_1942 940d2689cf490e81c471a43dd6166534 340 SUPERFAMILY SSF48179 187 339 1.34E-50 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_1942 940d2689cf490e81c471a43dd6166534 340 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 188 328 9.1E-45 T 14-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 D521_1942 940d2689cf490e81c471a43dd6166534 340 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 167 2.0E-36 T 14-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 D521_1942 940d2689cf490e81c471a43dd6166534 340 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 330 33.301 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 D521_1942 940d2689cf490e81c471a43dd6166534 340 SUPERFAMILY SSF51735 1 188 3.14E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1942 940d2689cf490e81c471a43dd6166534 340 Gene3D G3DSA:3.40.50.720 1 195 2.6E-48 T 14-10-2018 D521_1942 940d2689cf490e81c471a43dd6166534 340 Gene3D G3DSA:1.10.1040.10 197 340 6.6E-45 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 D521_1942 940d2689cf490e81c471a43dd6166534 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 141 161 3.3E-36 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 D521_1942 940d2689cf490e81c471a43dd6166534 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 181 205 3.3E-36 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 D521_1942 940d2689cf490e81c471a43dd6166534 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 206 230 3.3E-36 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 D521_1942 940d2689cf490e81c471a43dd6166534 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 246 263 3.3E-36 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 D521_1942 940d2689cf490e81c471a43dd6166534 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 5 22 3.3E-36 T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 D521_1942 940d2689cf490e81c471a43dd6166534 340 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 196 217 - T 14-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 D521_2110 c1f42b9229b0b196883be6075bbb3143 171 PRINTS PR01576 Peptide deformylase signature 33 62 3.7E-36 T 14-10-2018 IPR023635 Peptide deformylase D521_2110 c1f42b9229b0b196883be6075bbb3143 171 PRINTS PR01576 Peptide deformylase signature 102 120 3.7E-36 T 14-10-2018 IPR023635 Peptide deformylase D521_2110 c1f42b9229b0b196883be6075bbb3143 171 PRINTS PR01576 Peptide deformylase signature 90 101 3.7E-36 T 14-10-2018 IPR023635 Peptide deformylase D521_2110 c1f42b9229b0b196883be6075bbb3143 171 PRINTS PR01576 Peptide deformylase signature 121 150 3.7E-36 T 14-10-2018 IPR023635 Peptide deformylase D521_2110 c1f42b9229b0b196883be6075bbb3143 171 Gene3D G3DSA:3.90.45.10 1 167 1.0E-62 T 14-10-2018 IPR036821 Peptide deformylase superfamily D521_2110 c1f42b9229b0b196883be6075bbb3143 171 Hamap MF_00163 Peptide deformylase [def]. 2 163 29.529 T 14-10-2018 IPR023635 Peptide deformylase D521_2110 c1f42b9229b0b196883be6075bbb3143 171 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 161 3.9E-56 T 14-10-2018 IPR023635 Peptide deformylase D521_2110 c1f42b9229b0b196883be6075bbb3143 171 SUPERFAMILY SSF56420 1 160 2.36E-59 T 14-10-2018 IPR036821 Peptide deformylase superfamily D521_2110 c1f42b9229b0b196883be6075bbb3143 171 Pfam PF01327 Polypeptide deformylase 5 153 3.6E-50 T 14-10-2018 IPR023635 Peptide deformylase D521_2110 c1f42b9229b0b196883be6075bbb3143 171 PIRSF PIRSF004749 1 170 5.2E-57 T 14-10-2018 IPR023635 Peptide deformylase D521_0094 0e318f4787afaaa55af2348cd049d541 487 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 144 468 4.4E-29 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 D521_0094 0e318f4787afaaa55af2348cd049d541 487 SUPERFAMILY SSF46548 2 154 2.01E-38 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_0094 0e318f4787afaaa55af2348cd049d541 487 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 486 5.5E-219 T 14-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 D521_0094 0e318f4787afaaa55af2348cd049d541 487 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 1.2E-21 T 14-10-2018 D521_0094 0e318f4787afaaa55af2348cd049d541 487 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 1.2E-21 T 14-10-2018 D521_0094 0e318f4787afaaa55af2348cd049d541 487 PRINTS PR00419 Adrenodoxin reductase family signature 215 225 1.2E-21 T 14-10-2018 D521_0094 0e318f4787afaaa55af2348cd049d541 487 PRINTS PR00419 Adrenodoxin reductase family signature 296 310 1.2E-21 T 14-10-2018 D521_0094 0e318f4787afaaa55af2348cd049d541 487 SUPERFAMILY SSF51971 142 410 4.71E-66 T 14-10-2018 D521_0094 0e318f4787afaaa55af2348cd049d541 487 SUPERFAMILY SSF51971 383 481 1.29E-11 T 14-10-2018 D521_0094 0e318f4787afaaa55af2348cd049d541 487 Gene3D G3DSA:3.50.50.60 261 409 2.2E-36 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0094 0e318f4787afaaa55af2348cd049d541 487 Gene3D G3DSA:3.40.50.720 143 260 4.2E-17 T 14-10-2018 D521_0094 0e318f4787afaaa55af2348cd049d541 487 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 131 5.3E-24 T 14-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 D521_0094 0e318f4787afaaa55af2348cd049d541 487 Gene3D G3DSA:1.10.1060.10 8 142 4.2E-23 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Hamap MF_00054_B Elongation factor G [fusA]. 6 698 112.847 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 SUPERFAMILY SSF50447 255 407 2.21E-35 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Gene3D G3DSA:3.30.70.870 411 488 1.4E-33 T 14-10-2018 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 698 0.0 T 14-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Gene3D G3DSA:3.30.70.240 610 681 3.6E-89 T 14-10-2018 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 SUPERFAMILY SSF54211 484 605 8.6E-44 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Pfam PF00679 Elongation factor G C-terminus 606 692 1.1E-31 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 SUPERFAMILY SSF54980 409 486 1.91E-25 T 14-10-2018 IPR035647 EF-G domain III/V-like D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Pfam PF03144 Elongation factor Tu domain 2 329 396 1.7E-18 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Pfam PF14492 Elongation Factor G, domain II 409 483 6.7E-35 T 14-10-2018 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 SMART SM00889 485 604 4.5E-74 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Pfam PF00009 Elongation factor Tu GTP binding domain 9 288 3.9E-64 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Gene3D G3DSA:2.40.30.10 301 410 7.1E-42 T 14-10-2018 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 187 2.3E-32 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Pfam PF03764 Elongation factor G, domain IV 484 604 2.8E-47 T 14-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 SUPERFAMILY SSF54980 609 695 3.21E-29 T 14-10-2018 IPR035647 EF-G domain III/V-like D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 PRINTS PR00315 GTP-binding elongation factor signature 137 146 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 PRINTS PR00315 GTP-binding elongation factor signature 85 95 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 PRINTS PR00315 GTP-binding elongation factor signature 101 112 4.3E-15 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 SUPERFAMILY SSF52540 6 288 2.27E-105 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Gene3D G3DSA:3.30.230.10 489 694 3.6E-89 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 SMART SM00838 606 694 2.8E-55 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like D521_0049 2d3cb9e4049317e0f65ffc5c69ef6eb5 700 Gene3D G3DSA:3.40.50.300 1 300 1.5E-113 T 14-10-2018 D521_0864 a285af46fbedf29ce29b46149e369a81 473 Gene3D G3DSA:1.20.120.640 317 473 3.5E-39 T 14-10-2018 D521_0864 a285af46fbedf29ce29b46149e369a81 473 Pfam PF09190 DALR domain 353 411 2.4E-17 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 D521_0864 a285af46fbedf29ce29b46149e369a81 473 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 15 324 5.8E-126 T 14-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 D521_0864 a285af46fbedf29ce29b46149e369a81 473 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 2 472 1.4E-165 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 D521_0864 a285af46fbedf29ce29b46149e369a81 473 SUPERFAMILY SSF47323 329 471 5.75E-32 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0864 a285af46fbedf29ce29b46149e369a81 473 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 2 472 38.732 T 14-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 D521_0864 a285af46fbedf29ce29b46149e369a81 473 SMART SM00840 353 411 1.7E-21 T 14-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 D521_0864 a285af46fbedf29ce29b46149e369a81 473 SUPERFAMILY SSF52374 2 324 2.0E-95 T 14-10-2018 D521_0864 a285af46fbedf29ce29b46149e369a81 473 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 194 212 2.6E-29 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 D521_0864 a285af46fbedf29ce29b46149e369a81 473 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 2.6E-29 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 D521_0864 a285af46fbedf29ce29b46149e369a81 473 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 225 246 2.6E-29 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 D521_0864 a285af46fbedf29ce29b46149e369a81 473 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 2.6E-29 T 14-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 D521_0864 a285af46fbedf29ce29b46149e369a81 473 Gene3D G3DSA:3.40.50.620 1 316 1.6E-130 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1531 e49f0d79eaeab0af18be63373dc7d823 411 Gene3D G3DSA:1.20.1250.20 9 401 5.0E-45 T 14-10-2018 D521_1531 e49f0d79eaeab0af18be63373dc7d823 411 SUPERFAMILY SSF103473 9 402 7.98E-48 T 14-10-2018 IPR036259 MFS transporter superfamily D521_1531 e49f0d79eaeab0af18be63373dc7d823 411 Pfam PF07690 Major Facilitator Superfamily 13 363 4.6E-37 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.3E-42 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 PRINTS PR00340 P-II protein signature 23 41 5.6E-43 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 PRINTS PR00340 P-II protein signature 52 75 5.6E-43 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 PRINTS PR00340 P-II protein signature 83 103 5.6E-43 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 PRINTS PR00340 P-II protein signature 2 17 5.6E-43 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 SMART SM00938 4 105 1.0E-66 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 SUPERFAMILY SSF54913 1 112 1.33E-45 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 Gene3D G3DSA:3.30.70.120 1 112 1.0E-46 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal D521_1955 cd104efd9e84fbb295484dfae1c15e91 112 PIRSF PIRSF039144 1 112 6.0E-54 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_1945 d0f6aadc247ca39c30f8e5cf3af2c300 137 Gene3D G3DSA:3.40.250.10 36 137 8.9E-24 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1945 d0f6aadc247ca39c30f8e5cf3af2c300 137 Pfam PF00581 Rhodanese-like domain 39 131 1.6E-16 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1945 d0f6aadc247ca39c30f8e5cf3af2c300 137 SMART SM00450 37 134 1.2E-16 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1945 d0f6aadc247ca39c30f8e5cf3af2c300 137 SUPERFAMILY SSF52821 17 137 1.7E-28 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_2001 14a19c009da74f18d475b4c05f76716f 652 Pfam PF01464 Transglycosylase SLT domain 494 590 1.4E-21 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 D521_2001 14a19c009da74f18d475b4c05f76716f 652 SUPERFAMILY SSF53955 478 639 1.91E-42 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily D521_2001 14a19c009da74f18d475b4c05f76716f 652 Pfam PF14718 Soluble lytic murein transglycosylase L domain 407 466 1.0E-5 T 14-10-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 D521_2001 14a19c009da74f18d475b4c05f76716f 652 Gene3D G3DSA:1.10.530.10 472 638 6.8E-40 T 14-10-2018 D521_2001 14a19c009da74f18d475b4c05f76716f 652 SUPERFAMILY SSF48435 51 476 7.85E-90 T 14-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 D521_2001 14a19c009da74f18d475b4c05f76716f 652 Gene3D G3DSA:1.25.20.10 241 387 5.7E-20 T 14-10-2018 D521_2001 14a19c009da74f18d475b4c05f76716f 652 Gene3D G3DSA:1.25.20.10 51 239 1.4E-25 T 14-10-2018 D521_1396 6506ba905e25da89690f1fb28bba6240 273 SUPERFAMILY SSF82689 174 272 8.37E-16 T 14-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 D521_1396 6506ba905e25da89690f1fb28bba6240 273 SUPERFAMILY SSF50182 107 172 1.05E-16 T 14-10-2018 IPR010920 LSM domain superfamily D521_1396 6506ba905e25da89690f1fb28bba6240 273 SUPERFAMILY SSF82861 22 103 1.31E-13 T 14-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 D521_1396 6506ba905e25da89690f1fb28bba6240 273 Gene3D G3DSA:2.30.30.60 122 171 2.4E-17 T 14-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily D521_1396 6506ba905e25da89690f1fb28bba6240 273 Pfam PF00924 Mechanosensitive ion channel 65 257 1.4E-36 T 14-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 D521_1396 6506ba905e25da89690f1fb28bba6240 273 Gene3D G3DSA:3.30.70.100 172 264 1.8E-7 T 14-10-2018 D521_1989 6aee1418086fa555c1ca7746791814d1 287 SUPERFAMILY SSF51182 11 285 2.7E-79 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily D521_1989 6aee1418086fa555c1ca7746791814d1 287 Gene3D G3DSA:2.60.120.10 149 252 6.8E-85 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_1989 6aee1418086fa555c1ca7746791814d1 287 PIRSF PIRSF006232 3 287 3.5E-88 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 D521_1989 6aee1418086fa555c1ca7746791814d1 287 Pfam PF02678 Pirin 26 127 2.5E-34 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 D521_1989 6aee1418086fa555c1ca7746791814d1 287 Gene3D G3DSA:2.60.120.10 17 278 6.8E-85 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_1989 6aee1418086fa555c1ca7746791814d1 287 Pfam PF05726 Pirin C-terminal cupin domain 183 283 5.5E-26 T 14-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 D521_1540 540b8952016f5e9c94462e45b30a9969 62 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 9 50 8.8E-15 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 D521_1540 540b8952016f5e9c94462e45b30a9969 62 Pfam PF04995 Heme exporter protein D (CcmD) 12 50 3.3E-13 T 14-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 D521_0152 bcfe29d58c9796ea4926af14d8afe351 384 Pfam PF06725 3D domain 308 381 2.3E-22 T 14-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 D521_0152 bcfe29d58c9796ea4926af14d8afe351 384 SUPERFAMILY SSF50685 54 384 1.22E-117 T 14-10-2018 IPR036908 RlpA-like domain superfamily D521_0152 bcfe29d58c9796ea4926af14d8afe351 384 PIRSF PIRSF019422 9 384 5.9E-112 T 14-10-2018 IPR026044 Membrane-bound lytic murein transglycosylase A D521_0152 bcfe29d58c9796ea4926af14d8afe351 384 Gene3D G3DSA:2.40.40.10 292 384 8.8E-37 T 14-10-2018 IPR036908 RlpA-like domain superfamily D521_0152 bcfe29d58c9796ea4926af14d8afe351 384 Gene3D G3DSA:2.40.40.10 42 162 1.6E-29 T 14-10-2018 IPR036908 RlpA-like domain superfamily D521_0152 bcfe29d58c9796ea4926af14d8afe351 384 SMART SM00925 149 284 2.7E-67 T 14-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 D521_0152 bcfe29d58c9796ea4926af14d8afe351 384 Pfam PF03562 MltA specific insert domain 71 284 2.8E-68 T 14-10-2018 IPR005300 Lytic transglycosylase MltA, domain B GO:0004553 D521_0152 bcfe29d58c9796ea4926af14d8afe351 384 Gene3D G3DSA:2.40.240.50 170 286 1.2E-43 T 14-10-2018 D521_1869 bcf1705b93ba9533c0b694ba9681a806 338 Gene3D G3DSA:1.10.1200.80 257 332 1.9E-14 T 14-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 D521_1869 bcf1705b93ba9533c0b694ba9681a806 338 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 3 325 9.9E-125 T 14-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 D521_1869 bcf1705b93ba9533c0b694ba9681a806 338 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 94 112 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 D521_1869 bcf1705b93ba9533c0b694ba9681a806 338 Pfam PF01207 Dihydrouridine synthase (Dus) 14 324 2.9E-106 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 D521_1869 bcf1705b93ba9533c0b694ba9681a806 338 PIRSF PIRSF006621 1 332 4.2E-108 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 D521_1869 bcf1705b93ba9533c0b694ba9681a806 338 Hamap MF_02042 tRNA-dihydrouridine synthase B [dusB]. 1 326 49.765 T 14-10-2018 IPR032887 tRNA-dihydrouridine synthase B GO:0002943|GO:0017150 D521_1869 bcf1705b93ba9533c0b694ba9681a806 338 Gene3D G3DSA:3.20.20.70 7 252 1.1E-78 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1869 bcf1705b93ba9533c0b694ba9681a806 338 SUPERFAMILY SSF51395 10 325 1.87E-89 T 14-10-2018 D521_0308 4d41bcd215a4885d71c5523223c045b7 330 SUPERFAMILY SSF51735 17 328 2.26E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0308 4d41bcd215a4885d71c5523223c045b7 330 Pfam PF16363 GDP-mannose 4,6 dehydratase 20 326 5.4E-96 T 14-10-2018 IPR016040 NAD(P)-binding domain D521_0308 4d41bcd215a4885d71c5523223c045b7 330 Gene3D G3DSA:3.40.50.720 19 316 1.7E-116 T 14-10-2018 D521_0308 4d41bcd215a4885d71c5523223c045b7 330 Gene3D G3DSA:3.90.25.10 200 328 1.7E-116 T 14-10-2018 D521_1171 871ac2581a783f189273e078965915d3 153 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 137 1.6E-4 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain D521_1171 871ac2581a783f189273e078965915d3 153 SUPERFAMILY SSF54593 1 142 1.27E-17 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase D521_1171 871ac2581a783f189273e078965915d3 153 Gene3D G3DSA:3.10.180.10 1 141 2.5E-19 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase D521_1122 7829b52b315b4d9557dd2095a04abcd7 230 SUPERFAMILY SSF56529 23 230 3.92E-72 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 D521_1122 7829b52b315b4d9557dd2095a04abcd7 230 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 28 228 2.8E-53 T 14-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 D521_1122 7829b52b315b4d9557dd2095a04abcd7 230 Gene3D G3DSA:3.90.850.10 1 230 1.1E-89 T 14-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 D521_0833 56d908b8b8a529cd4403cc57878125b8 606 Gene3D G3DSA:1.20.1510.10 27 220 4.7E-41 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily D521_0833 56d908b8b8a529cd4403cc57878125b8 606 SUPERFAMILY SSF160240 231 297 8.89E-6 T 14-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 D521_0833 56d908b8b8a529cd4403cc57878125b8 606 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 29 298 7.8E-80 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 D521_0833 56d908b8b8a529cd4403cc57878125b8 606 Pfam PF12697 Alpha/beta hydrolase family 354 598 5.0E-13 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_0833 56d908b8b8a529cd4403cc57878125b8 606 SUPERFAMILY SSF161111 27 221 7.98E-52 T 14-10-2018 IPR027469 Cation efflux transmembrane domain superfamily D521_0833 56d908b8b8a529cd4403cc57878125b8 606 Pfam PF01545 Cation efflux family 30 219 1.6E-43 T 14-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 D521_0833 56d908b8b8a529cd4403cc57878125b8 606 Gene3D G3DSA:3.40.50.1820 315 606 5.5E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0833 56d908b8b8a529cd4403cc57878125b8 606 SUPERFAMILY SSF53474 330 599 2.83E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0675 6d420111e279b0d9fa1184ceaaab3d5a 144 Gene3D G3DSA:1.10.760.10 21 144 6.3E-40 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0675 6d420111e279b0d9fa1184ceaaab3d5a 144 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 54 143 1.8E-19 T 14-10-2018 IPR030999 Sulfur oxidation c-type cytochrome SoxX D521_0675 6d420111e279b0d9fa1184ceaaab3d5a 144 SUPERFAMILY SSF46626 3 144 5.08E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0596 d2451f0e93c74c57e9189e279539ba14 456 Gene3D G3DSA:1.10.4100.10 27 421 1.8E-97 T 14-10-2018 D521_0596 d2451f0e93c74c57e9189e279539ba14 456 Gene3D G3DSA:3.30.1330.120 274 405 1.8E-97 T 14-10-2018 D521_0596 d2451f0e93c74c57e9189e279539ba14 456 Pfam PF03972 MmgE/PrpD family 8 445 2.3E-133 T 14-10-2018 IPR005656 MmgE/PrpD GO:0016829 D521_0596 d2451f0e93c74c57e9189e279539ba14 456 SUPERFAMILY SSF103378 4 451 3.01E-114 T 14-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 D521_1197 7bcde76793a5a10beb2c3d790624d6e5 215 SUPERFAMILY SSF109755 17 208 1.96E-6 T 14-10-2018 D521_1197 7bcde76793a5a10beb2c3d790624d6e5 215 Gene3D G3DSA:1.20.58.220 13 215 1.1E-55 T 14-10-2018 IPR038078 PhoU-like domain superfamily D521_1197 7bcde76793a5a10beb2c3d790624d6e5 215 Pfam PF01865 Protein of unknown function DUF47 16 213 5.6E-25 T 14-10-2018 IPR018445 Putative phosphate transport regulator D521_0909 caa2087620be1117790e9786bdc2fc66 678 SUPERFAMILY SSF51230 601 678 7.98E-20 T 14-10-2018 IPR011053 Single hybrid motif D521_0909 caa2087620be1117790e9786bdc2fc66 678 Gene3D G3DSA:3.30.470.130 1 454 2.4E-203 T 14-10-2018 D521_0909 caa2087620be1117790e9786bdc2fc66 678 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 157 171 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0909 caa2087620be1117790e9786bdc2fc66 678 SUPERFAMILY SSF52440 3 117 3.38E-51 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily D521_0909 caa2087620be1117790e9786bdc2fc66 678 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 634 651 - T 14-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 D521_0909 caa2087620be1117790e9786bdc2fc66 678 Pfam PF00289 Biotin carboxylase, N-terminal domain 5 114 3.5E-48 T 14-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 D521_0909 caa2087620be1117790e9786bdc2fc66 678 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 119 326 5.2E-80 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0909 caa2087620be1117790e9786bdc2fc66 678 Pfam PF02785 Biotin carboxylase C-terminal domain 340 447 3.1E-39 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 D521_0909 caa2087620be1117790e9786bdc2fc66 678 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 5 448 3.8E-198 T 14-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 D521_0909 caa2087620be1117790e9786bdc2fc66 678 Gene3D G3DSA:3.30.700.30 455 598 2.0E-13 T 14-10-2018 D521_0909 caa2087620be1117790e9786bdc2fc66 678 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0909 caa2087620be1117790e9786bdc2fc66 678 Gene3D G3DSA:2.40.50.100 610 678 9.1E-20 T 14-10-2018 D521_0909 caa2087620be1117790e9786bdc2fc66 678 SUPERFAMILY SSF51246 335 450 5.76E-43 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 D521_0909 caa2087620be1117790e9786bdc2fc66 678 Pfam PF00364 Biotin-requiring enzyme 612 676 9.9E-17 T 14-10-2018 IPR000089 Biotin/lipoyl attachment D521_0909 caa2087620be1117790e9786bdc2fc66 678 SMART SM00878 340 447 5.7E-63 T 14-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 D521_0909 caa2087620be1117790e9786bdc2fc66 678 SUPERFAMILY SSF56059 87 352 9.93E-68 T 14-10-2018 D521_0785 121513b298140ce6629293435ebb1138 289 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 26 41 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_0785 121513b298140ce6629293435ebb1138 289 SUPERFAMILY SSF51717 20 289 2.09E-97 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_0785 121513b298140ce6629293435ebb1138 289 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 60 73 - T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_0785 121513b298140ce6629293435ebb1138 289 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 26 287 2.8E-98 T 14-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 D521_0785 121513b298140ce6629293435ebb1138 289 Pfam PF00809 Pterin binding enzyme 27 272 1.2E-81 T 14-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_0785 121513b298140ce6629293435ebb1138 289 Gene3D G3DSA:3.20.20.20 9 289 5.5E-106 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1693 ceacce41f27ffc4638d7a151621db71e 634 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 14-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 D521_1693 ceacce41f27ffc4638d7a151621db71e 634 Gene3D G3DSA:3.40.50.920 492 621 3.0E-37 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 D521_1693 ceacce41f27ffc4638d7a151621db71e 634 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 622 46.087 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 D521_1693 ceacce41f27ffc4638d7a151621db71e 634 SUPERFAMILY SSF52518 314 500 3.1E-57 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_1693 ceacce41f27ffc4638d7a151621db71e 634 SUPERFAMILY SSF52518 3 378 6.35E-81 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_1693 ceacce41f27ffc4638d7a151621db71e 634 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 D521_1693 ceacce41f27ffc4638d7a151621db71e 634 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 619 3.6E-258 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 D521_1693 ceacce41f27ffc4638d7a151621db71e 634 Pfam PF02779 Transketolase, pyrimidine binding domain 317 475 4.0E-39 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain D521_1693 ceacce41f27ffc4638d7a151621db71e 634 Pfam PF02780 Transketolase, C-terminal domain 505 613 4.3E-21 T 14-10-2018 IPR033248 Transketolase, C-terminal domain D521_1693 ceacce41f27ffc4638d7a151621db71e 634 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 279 6.5E-120 T 14-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 D521_1693 ceacce41f27ffc4638d7a151621db71e 634 Gene3D G3DSA:3.40.50.970 313 486 2.5E-66 T 14-10-2018 D521_1693 ceacce41f27ffc4638d7a151621db71e 634 SUPERFAMILY SSF52922 488 617 4.06E-28 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 D521_1693 ceacce41f27ffc4638d7a151621db71e 634 SMART SM00861 316 480 9.8E-68 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain D521_0564 6334ae0e427d56ac80fbf3da5819fa58 99 SUPERFAMILY SSF82057 28 99 2.7E-26 T 14-10-2018 D521_0564 6334ae0e427d56ac80fbf3da5819fa58 99 TIGRFAM TIGR00686 phnA: putative alkylphosphonate utilization operon protein PhnA 2 99 9.5E-40 T 14-10-2018 IPR004624 PhnA protein D521_0564 6334ae0e427d56ac80fbf3da5819fa58 99 Gene3D G3DSA:2.30.30.40 30 99 4.1E-31 T 14-10-2018 D521_0564 6334ae0e427d56ac80fbf3da5819fa58 99 Pfam PF03831 PhnA domain 33 99 9.1E-31 T 14-10-2018 IPR013988 PhnA protein, C-terminal D521_0564 6334ae0e427d56ac80fbf3da5819fa58 99 SUPERFAMILY SSF57783 2 25 2.04E-5 T 14-10-2018 D521_0564 6334ae0e427d56ac80fbf3da5819fa58 99 Gene3D G3DSA:2.20.25.10 1 29 3.3E-7 T 14-10-2018 D521_1143 04ec95fba7172e621d30522fc6abf12d 405 SUPERFAMILY SSF160996 190 350 2.22E-30 T 14-10-2018 D521_1143 04ec95fba7172e621d30522fc6abf12d 405 Gene3D G3DSA:3.50.50.60 8 399 2.6E-112 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1143 04ec95fba7172e621d30522fc6abf12d 405 Pfam PF03486 HI0933-like protein 6 403 2.2E-120 T 14-10-2018 D521_1143 04ec95fba7172e621d30522fc6abf12d 405 Gene3D G3DSA:1.10.8.260 269 333 2.6E-112 T 14-10-2018 IPR023166 HI0933-like insert domain superfamily D521_1143 04ec95fba7172e621d30522fc6abf12d 405 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.0E-6 T 14-10-2018 D521_1143 04ec95fba7172e621d30522fc6abf12d 405 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 156 165 3.0E-6 T 14-10-2018 D521_1143 04ec95fba7172e621d30522fc6abf12d 405 SUPERFAMILY SSF51905 1 405 2.05E-51 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1143 04ec95fba7172e621d30522fc6abf12d 405 Gene3D G3DSA:2.40.30.10 189 350 2.6E-112 T 14-10-2018 D521_1143 04ec95fba7172e621d30522fc6abf12d 405 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 8 402 2.9E-109 T 14-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like D521_1176 e87912fa0060aace97e004deeb7c8a69 251 Pfam PF00005 ABC transporter 25 180 2.6E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_1176 e87912fa0060aace97e004deeb7c8a69 251 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_1176 e87912fa0060aace97e004deeb7c8a69 251 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 249 1.1E-9 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal D521_1176 e87912fa0060aace97e004deeb7c8a69 251 SUPERFAMILY SSF52540 8 249 1.7E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1176 e87912fa0060aace97e004deeb7c8a69 251 Gene3D G3DSA:3.40.50.300 4 250 3.3E-66 T 14-10-2018 D521_1176 e87912fa0060aace97e004deeb7c8a69 251 SMART SM00382 34 228 1.2E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0671 1d2ef654fce06be8910b4cf4bec3b578 241 Pfam PF04172 LrgB-like family 25 238 1.2E-68 T 14-10-2018 IPR007300 CidB/LrgB family D521_1076 3bce530b417d2648b4c905be2923ba52 422 Gene3D G3DSA:3.30.413.10 306 422 1.5E-37 T 14-10-2018 D521_1076 3bce530b417d2648b4c905be2923ba52 422 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 32 411 1.9E-116 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 D521_1076 3bce530b417d2648b4c905be2923ba52 422 Gene3D G3DSA:3.20.20.20 17 305 3.0E-96 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1076 3bce530b417d2648b4c905be2923ba52 422 PIRSF PIRSF004640 14 422 5.3E-128 T 14-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 D521_1076 3bce530b417d2648b4c905be2923ba52 422 Pfam PF04551 GcpE protein 32 412 1.6E-113 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 D521_1076 3bce530b417d2648b4c905be2923ba52 422 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 20 416 28.69 T 14-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 D521_0205 52b3c8fcb6f40121c7267f7a1cf7f43d 271 SMART SM00644 93 245 5.1E-35 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 D521_0205 52b3c8fcb6f40121c7267f7a1cf7f43d 271 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 106 245 5.7E-22 T 14-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 D521_0205 52b3c8fcb6f40121c7267f7a1cf7f43d 271 SUPERFAMILY SSF55846 81 255 8.24E-52 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 D521_0205 52b3c8fcb6f40121c7267f7a1cf7f43d 271 Gene3D G3DSA:3.40.80.10 79 263 4.8E-45 T 14-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 D521_0315 b6700ca5658a23e2992f1d4001088d12 367 Pfam PF16363 GDP-mannose 4,6 dehydratase 24 339 1.2E-35 T 14-10-2018 IPR016040 NAD(P)-binding domain D521_0315 b6700ca5658a23e2992f1d4001088d12 367 Gene3D G3DSA:3.90.25.10 205 367 4.7E-66 T 14-10-2018 D521_0315 b6700ca5658a23e2992f1d4001088d12 367 TIGRFAM TIGR02622 CDP_4_6_dhtase: CDP-glucose 4,6-dehydratase 16 364 1.5E-158 T 14-10-2018 IPR013445 CDP-glucose 4,6-dehydratase KEGG: 00520+4.2.1.45|MetaCyc: PWY-5833 D521_0315 b6700ca5658a23e2992f1d4001088d12 367 Gene3D G3DSA:3.40.50.720 12 204 1.7E-47 T 14-10-2018 D521_0315 b6700ca5658a23e2992f1d4001088d12 367 SUPERFAMILY SSF51735 14 350 6.18E-62 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0199 d2904bc82ca71057eb12872131f36cd2 260 SUPERFAMILY SSF53633 7 257 3.53E-65 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily D521_0199 d2904bc82ca71057eb12872131f36cd2 260 PIRSF PIRSF000729 2 260 3.0E-90 T 14-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 D521_0199 d2904bc82ca71057eb12872131f36cd2 260 ProSitePatterns PS00902 Glutamate 5-kinase signature. 209 226 - T 14-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 D521_0199 d2904bc82ca71057eb12872131f36cd2 260 PRINTS PR00474 Glutamate 5-kinase family signature 78 106 8.5E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 D521_0199 d2904bc82ca71057eb12872131f36cd2 260 PRINTS PR00474 Glutamate 5-kinase family signature 211 231 8.5E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 D521_0199 d2904bc82ca71057eb12872131f36cd2 260 PRINTS PR00474 Glutamate 5-kinase family signature 44 58 8.5E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 D521_0199 d2904bc82ca71057eb12872131f36cd2 260 PRINTS PR00474 Glutamate 5-kinase family signature 118 139 8.5E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 D521_0199 d2904bc82ca71057eb12872131f36cd2 260 PRINTS PR00474 Glutamate 5-kinase family signature 150 177 8.5E-51 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 D521_0199 d2904bc82ca71057eb12872131f36cd2 260 Hamap MF_00456 Glutamate 5-kinase [proB]. 7 260 34.692 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 D521_0199 d2904bc82ca71057eb12872131f36cd2 260 TIGRFAM TIGR01027 proB: glutamate 5-kinase 7 259 2.0E-89 T 14-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 D521_0199 d2904bc82ca71057eb12872131f36cd2 260 Pfam PF00696 Amino acid kinase family 7 236 5.3E-38 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 D521_0199 d2904bc82ca71057eb12872131f36cd2 260 Gene3D G3DSA:3.40.1160.10 1 260 4.4E-89 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily D521_0290 6a319b9d6abae1a71487fd87ed9e48da 213 Pfam PF01618 MotA/TolQ/ExbB proton channel family 86 195 2.6E-26 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel D521_0120 793c1efdcd98182afc6cdf65529a04bb 140 SUPERFAMILY SSF81330 13 135 2.88E-33 T 14-10-2018 IPR036019 Gated mechanosensitive channel D521_0120 793c1efdcd98182afc6cdf65529a04bb 140 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 13 26 - T 14-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site D521_0120 793c1efdcd98182afc6cdf65529a04bb 140 Gene3D G3DSA:1.10.1200.120 3 140 7.9E-38 T 14-10-2018 IPR036019 Gated mechanosensitive channel D521_0120 793c1efdcd98182afc6cdf65529a04bb 140 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 4 139 2.5E-34 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 D521_0120 793c1efdcd98182afc6cdf65529a04bb 140 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 4 139 4.8E-41 T 14-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L D521_0120 793c1efdcd98182afc6cdf65529a04bb 140 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 95 103 2.6E-11 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 D521_0120 793c1efdcd98182afc6cdf65529a04bb 140 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 104 113 2.6E-11 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 D521_0120 793c1efdcd98182afc6cdf65529a04bb 140 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 6 20 2.6E-11 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 D521_0120 793c1efdcd98182afc6cdf65529a04bb 140 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 3 140 22.969 T 14-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 D521_0391 d29849a62d2c30e85c60fe19f47f4100 466 Gene3D G3DSA:1.20.1600.10 66 454 4.0E-66 T 14-10-2018 D521_0391 d29849a62d2c30e85c60fe19f47f4100 466 SUPERFAMILY SSF56954 45 451 7.06E-73 T 14-10-2018 D521_0391 d29849a62d2c30e85c60fe19f47f4100 466 Pfam PF02321 Outer membrane efflux protein 281 450 8.6E-20 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_0391 d29849a62d2c30e85c60fe19f47f4100 466 Pfam PF02321 Outer membrane efflux protein 76 255 2.0E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_0603 864e48551ac3c556e1da07949fb9350e 559 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0603 864e48551ac3c556e1da07949fb9350e 559 SUPERFAMILY SSF52540 300 551 2.45E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0603 864e48551ac3c556e1da07949fb9350e 559 SUPERFAMILY SSF52540 14 277 8.4E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0603 864e48551ac3c556e1da07949fb9350e 559 Gene3D G3DSA:3.40.50.300 13 289 1.3E-74 T 14-10-2018 D521_0603 864e48551ac3c556e1da07949fb9350e 559 Gene3D G3DSA:3.40.50.300 294 559 8.7E-80 T 14-10-2018 D521_0603 864e48551ac3c556e1da07949fb9350e 559 ProSitePatterns PS00211 ABC transporters family signature. 174 188 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0603 864e48551ac3c556e1da07949fb9350e 559 Pfam PF00005 ABC transporter 324 481 5.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0603 864e48551ac3c556e1da07949fb9350e 559 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 257 283 6.4E-4 T 14-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 D521_0603 864e48551ac3c556e1da07949fb9350e 559 Pfam PF00005 ABC transporter 36 201 5.7E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0603 864e48551ac3c556e1da07949fb9350e 559 SMART SM00382 43 255 9.7E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0603 864e48551ac3c556e1da07949fb9350e 559 SMART SM00382 333 530 1.4E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1766 d1b9f41d2be8a5121866ebe82dec8043 241 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 78 92 - T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 D521_1766 d1b9f41d2be8a5121866ebe82dec8043 241 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 236 1.6E-82 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 D521_1766 d1b9f41d2be8a5121866ebe82dec8043 241 Gene3D G3DSA:3.20.20.10 1 240 2.2E-82 T 14-10-2018 IPR029066 PLP-binding barrel D521_1766 d1b9f41d2be8a5121866ebe82dec8043 241 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 6 235 32.351 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 D521_1766 d1b9f41d2be8a5121866ebe82dec8043 241 PIRSF PIRSF004848 1 241 1.4E-76 T 14-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 D521_1766 d1b9f41d2be8a5121866ebe82dec8043 241 SUPERFAMILY SSF51419 2 234 3.66E-76 T 14-10-2018 IPR029066 PLP-binding barrel D521_1766 d1b9f41d2be8a5121866ebe82dec8043 241 Pfam PF01168 Alanine racemase, N-terminal domain 26 236 5.5E-25 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0559 9740c169fcf61dc3828cb57097818703 518 Gene3D G3DSA:1.10.3720.10 2 262 1.8E-46 T 14-10-2018 IPR035906 MetI-like superfamily D521_0559 9740c169fcf61dc3828cb57097818703 518 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 67 252 2.5E-12 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 D521_0559 9740c169fcf61dc3828cb57097818703 518 SUPERFAMILY SSF161098 278 513 5.23E-30 T 14-10-2018 IPR035906 MetI-like superfamily D521_0559 9740c169fcf61dc3828cb57097818703 518 SUPERFAMILY SSF161098 5 254 4.06E-36 T 14-10-2018 IPR035906 MetI-like superfamily D521_0559 9740c169fcf61dc3828cb57097818703 518 Gene3D G3DSA:1.10.3720.10 280 518 2.2E-24 T 14-10-2018 IPR035906 MetI-like superfamily D521_1378 194c875b0fa11cd2450c17246ce1fe5b 205 Gene3D G3DSA:2.60.120.590 14 205 2.2E-61 T 14-10-2018 IPR037151 Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily D521_1378 194c875b0fa11cd2450c17246ce1fe5b 205 SUPERFAMILY SSF51197 15 203 2.75E-60 T 14-10-2018 D521_1378 194c875b0fa11cd2450c17246ce1fe5b 205 Pfam PF13532 2OG-Fe(II) oxygenase superfamily 25 201 2.6E-33 T 14-10-2018 IPR027450 Alpha-ketoglutarate-dependent dioxygenase AlkB-like D521_0551 ebcd8f647868fa5d2c6a156204908f51 113 SMART SM00530 53 107 5.2E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 D521_0551 ebcd8f647868fa5d2c6a156204908f51 113 Gene3D G3DSA:1.10.260.40 55 112 1.7E-19 T 14-10-2018 D521_0551 ebcd8f647868fa5d2c6a156204908f51 113 Pfam PF13560 Helix-turn-helix domain 57 101 5.5E-8 T 14-10-2018 D521_0551 ebcd8f647868fa5d2c6a156204908f51 113 SUPERFAMILY SSF47413 55 97 2.25E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 D521_1549 8196befd3ead7565f6f4173468ef3909 508 SUPERFAMILY SSF48173 227 487 7.19E-56 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 D521_1549 8196befd3ead7565f6f4173468ef3909 508 Gene3D G3DSA:1.10.10.1710 442 508 9.6E-19 T 14-10-2018 D521_1549 8196befd3ead7565f6f4173468ef3909 508 Gene3D G3DSA:1.10.579.10 321 441 1.4E-53 T 14-10-2018 D521_1549 8196befd3ead7565f6f4173468ef3909 508 Gene3D G3DSA:1.25.40.80 128 317 3.7E-113 T 14-10-2018 D521_1549 8196befd3ead7565f6f4173468ef3909 508 Pfam PF04244 Deoxyribodipyrimidine photo-lyase-related protein 5 226 2.8E-75 T 14-10-2018 IPR007357 Deoxyribodipyrimidine photolyase-related protein D521_1549 8196befd3ead7565f6f4173468ef3909 508 Gene3D G3DSA:3.40.50.620 6 228 3.7E-113 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0384 b88b55a14943083af168c83a986a4c9b 257 Pfam PF01925 Sulfite exporter TauE/SafE 21 250 1.0E-26 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 D521_0716 17fc054b92f53c87df4f62fa7d154758 200 Pfam PF01725 Ham1 family 5 190 1.7E-53 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 D521_0716 17fc054b92f53c87df4f62fa7d154758 200 Gene3D G3DSA:3.90.950.10 1 197 1.9E-70 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like D521_0716 17fc054b92f53c87df4f62fa7d154758 200 Hamap MF_01405 dITP/XTP pyrophosphatase. 3 195 46.441 T 14-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 D521_0716 17fc054b92f53c87df4f62fa7d154758 200 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 193 5.3E-53 T 14-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 D521_0716 17fc054b92f53c87df4f62fa7d154758 200 SUPERFAMILY SSF52972 2 193 5.23E-68 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like D521_1900 d017ba6e487c24616ab997e2e4655770 394 Gene3D G3DSA:1.20.1250.20 1 380 1.9E-68 T 14-10-2018 D521_1900 d017ba6e487c24616ab997e2e4655770 394 SUPERFAMILY SSF103473 7 378 7.32E-52 T 14-10-2018 IPR036259 MFS transporter superfamily D521_1900 d017ba6e487c24616ab997e2e4655770 394 ProSitePatterns PS00216 Sugar transport proteins signature 1. 64 80 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 D521_1900 d017ba6e487c24616ab997e2e4655770 394 Pfam PF07690 Major Facilitator Superfamily 18 343 1.3E-30 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_2035 fe42ebb9a880e8f730f0d10fa7a06390 472 Pfam PF00582 Universal stress protein family 352 471 2.8E-8 T 14-10-2018 IPR006016 UspA D521_2035 fe42ebb9a880e8f730f0d10fa7a06390 472 Gene3D G3DSA:3.40.50.620 332 471 2.5E-9 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_2035 fe42ebb9a880e8f730f0d10fa7a06390 472 Gene3D G3DSA:3.30.200.20 13 101 1.2E-7 T 14-10-2018 D521_2035 fe42ebb9a880e8f730f0d10fa7a06390 472 Pfam PF00069 Protein kinase domain 29 273 2.3E-38 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 D521_2035 fe42ebb9a880e8f730f0d10fa7a06390 472 SMART SM00220 23 287 2.2E-40 T 14-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 D521_2035 fe42ebb9a880e8f730f0d10fa7a06390 472 SUPERFAMILY SSF56112 19 288 6.23E-61 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily D521_2035 fe42ebb9a880e8f730f0d10fa7a06390 472 SUPERFAMILY SSF52402 331 471 1.67E-7 T 14-10-2018 D521_2035 fe42ebb9a880e8f730f0d10fa7a06390 472 Gene3D G3DSA:1.10.510.10 104 290 8.6E-46 T 14-10-2018 D521_2103 472804f800de9c8f7769b222ea38eb4c 591 Gene3D G3DSA:3.30.300.20 3 132 1.3E-14 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta D521_2103 472804f800de9c8f7769b222ea38eb4c 591 TIGRFAM TIGR03549 TIGR03549: YcaO domain protein 2 590 0.0 T 14-10-2018 IPR019938 YcaO domain protein D521_2103 472804f800de9c8f7769b222ea38eb4c 591 TIGRFAM TIGR00702 TIGR00702: YcaO-type kinase domain 159 550 3.1E-100 T 14-10-2018 IPR003776 YcaO-like domain D521_2103 472804f800de9c8f7769b222ea38eb4c 591 SUPERFAMILY SSF82784 1 128 5.23E-19 T 14-10-2018 IPR036102 OsmC/Ohr superfamily D521_2103 472804f800de9c8f7769b222ea38eb4c 591 Pfam PF02566 OsmC-like protein 32 126 8.4E-10 T 14-10-2018 IPR003718 OsmC/Ohr family D521_2103 472804f800de9c8f7769b222ea38eb4c 591 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 205 540 1.9E-68 T 14-10-2018 IPR003776 YcaO-like domain D521_0424 1f63c3bea21fbd02e9ee8a8985b5464d 460 SUPERFAMILY SSF103473 26 454 4.58E-37 T 14-10-2018 IPR036259 MFS transporter superfamily D521_0424 1f63c3bea21fbd02e9ee8a8985b5464d 460 Pfam PF07690 Major Facilitator Superfamily 37 416 8.2E-11 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_0424 1f63c3bea21fbd02e9ee8a8985b5464d 460 Gene3D G3DSA:1.20.1250.20 1 231 7.3E-79 T 14-10-2018 D521_0424 1f63c3bea21fbd02e9ee8a8985b5464d 460 TIGRFAM TIGR00886 2A0108: nitrite transporter 27 412 5.0E-103 T 14-10-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 D521_0424 1f63c3bea21fbd02e9ee8a8985b5464d 460 Gene3D G3DSA:1.20.1250.20 232 458 4.9E-77 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PIRSF PIRSF000350 1 477 1.5E-87 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 D521_0848 73238c3d6bd027501082239a50bd399d 478 SUPERFAMILY SSF51905 1 350 3.56E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 187 212 8.8E-80 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 355 376 8.8E-80 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 442 462 8.8E-80 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 320 327 8.8E-80 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 47 62 8.8E-80 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 290 8.8E-80 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 160 8.8E-80 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 8.8E-80 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 420 435 8.8E-80 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 Gene3D G3DSA:3.50.50.60 5 345 8.0E-111 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0848 73238c3d6bd027501082239a50bd399d 478 Gene3D G3DSA:3.50.50.60 167 289 8.0E-111 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0848 73238c3d6bd027501082239a50bd399d 478 SUPERFAMILY SSF55424 355 476 3.26E-44 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 D521_0848 73238c3d6bd027501082239a50bd399d 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 340 2.7E-70 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 D521_0848 73238c3d6bd027501082239a50bd399d 478 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 359 467 4.6E-40 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 7.6E-39 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 275 291 7.6E-39 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 7.6E-39 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 187 205 7.6E-39 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 305 327 7.6E-39 T 14-10-2018 D521_0848 73238c3d6bd027501082239a50bd399d 478 Gene3D G3DSA:3.30.390.30 358 478 2.0E-48 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 D521_0848 73238c3d6bd027501082239a50bd399d 478 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 5 478 2.2E-165 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 D521_0848 73238c3d6bd027501082239a50bd399d 478 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 48 58 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 D521_1424 911a2ef9dbbe4223c245469c1c969410 415 Gene3D G3DSA:3.40.47.10 1 259 1.5E-95 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 D521_1424 911a2ef9dbbe4223c245469c1c969410 415 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 8 251 3.7E-61 T 14-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal D521_1424 911a2ef9dbbe4223c245469c1c969410 415 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 8 411 5.4E-196 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 D521_1424 911a2ef9dbbe4223c245469c1c969410 415 SUPERFAMILY SSF53901 218 413 7.3E-68 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 D521_1424 911a2ef9dbbe4223c245469c1c969410 415 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 159 175 - T 14-10-2018 IPR018201 Beta-ketoacyl synthase, active site D521_1424 911a2ef9dbbe4223c245469c1c969410 415 Gene3D G3DSA:3.40.47.10 261 403 1.0E-49 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 D521_1424 911a2ef9dbbe4223c245469c1c969410 415 SMART SM00825 Beta-ketoacyl synthase 10 411 4.9E-16 T 14-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain D521_1424 911a2ef9dbbe4223c245469c1c969410 415 PIRSF PIRSF000447 5 415 2.8E-184 T 14-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 D521_1424 911a2ef9dbbe4223c245469c1c969410 415 SUPERFAMILY SSF53901 8 256 1.78E-80 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 D521_1424 911a2ef9dbbe4223c245469c1c969410 415 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 371 4.3E-34 T 14-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal D521_0071 a3fcf8d9c8dd8aa561d9a85746a1aa4a 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 142 9.5E-48 T 14-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0071 a3fcf8d9c8dd8aa561d9a85746a1aa4a 146 SUPERFAMILY SSF52080 4 142 2.62E-44 T 14-10-2018 IPR036227 Ribosomal L18e/L15P superfamily D521_0071 a3fcf8d9c8dd8aa561d9a85746a1aa4a 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 142 3.5E-27 T 14-10-2018 IPR021131 Ribosomal protein L18e/L15P D521_0071 a3fcf8d9c8dd8aa561d9a85746a1aa4a 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 145 19.485 T 14-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 D521_0071 a3fcf8d9c8dd8aa561d9a85746a1aa4a 146 Gene3D G3DSA:3.100.10.10 67 145 2.3E-11 T 14-10-2018 D521_2012 00a2482880bf3732a75b5f503e835364 193 Gene3D G3DSA:3.40.50.150 2 170 4.8E-26 T 14-10-2018 D521_2012 00a2482880bf3732a75b5f503e835364 193 Pfam PF07021 Methionine biosynthesis protein MetW 3 190 4.6E-77 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 D521_2012 00a2482880bf3732a75b5f503e835364 193 SUPERFAMILY SSF53335 4 172 8.51E-28 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_2012 00a2482880bf3732a75b5f503e835364 193 TIGRFAM TIGR02081 metW: methionine biosynthesis protein MetW 3 190 8.6E-80 T 14-10-2018 IPR010743 Methionine biosynthesis MetW KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 D521_0775 a63d328cc2a5094af923083fc90e8915 269 Pfam PF16123 Hydroxyacylglutathione hydrolase C-terminus 181 269 5.3E-26 T 14-10-2018 IPR032282 Hydroxyacylglutathione hydrolase, C-terminal domain KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 D521_0775 a63d328cc2a5094af923083fc90e8915 269 ProSitePatterns PS00743 Beta-lactamases class B signature 1. 55 75 - T 14-10-2018 IPR001018 Beta-lactamase, class-B, conserved site GO:0008270|GO:0008800|GO:0017001 D521_0775 a63d328cc2a5094af923083fc90e8915 269 Gene3D G3DSA:3.60.15.10 1 269 3.1E-83 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_0775 a63d328cc2a5094af923083fc90e8915 269 SMART SM00849 17 180 2.7E-25 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0775 a63d328cc2a5094af923083fc90e8915 269 PIRSF PIRSF005457 2 269 9.6E-97 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 D521_0775 a63d328cc2a5094af923083fc90e8915 269 Pfam PF00753 Metallo-beta-lactamase superfamily 18 180 1.6E-13 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0775 a63d328cc2a5094af923083fc90e8915 269 Hamap MF_01374 Hydroxyacylglutathione hydrolase [gloB]. 7 269 42.492 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 D521_0775 a63d328cc2a5094af923083fc90e8915 269 SUPERFAMILY SSF56281 7 269 3.93E-66 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_0775 a63d328cc2a5094af923083fc90e8915 269 TIGRFAM TIGR03413 GSH_gloB: hydroxyacylglutathione hydrolase 11 269 2.8E-96 T 14-10-2018 IPR017782 Hydroxyacylglutathione hydrolase GO:0004416|GO:0019243 KEGG: 00620+3.1.2.6|MetaCyc: PWY-5386 D521_1335 38781962ff6b6023103bded0ccff6b7c 200 Pfam PF01925 Sulfite exporter TauE/SafE 8 192 2.0E-21 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 Gene3D G3DSA:3.30.565.10 669 840 2.0E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1037 a86039ee748b29d0d0b052b7032f716e 844 Pfam PF00989 PAS fold 325 439 1.3E-14 T 14-10-2018 IPR013767 PAS fold GO:0006355 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 SMART SM00091 454 524 40.0 T 14-10-2018 IPR000014 PAS domain D521_1037 a86039ee748b29d0d0b052b7032f716e 844 SMART SM00091 322 390 1.0E-9 T 14-10-2018 IPR000014 PAS domain D521_1037 a86039ee748b29d0d0b052b7032f716e 844 SUPERFAMILY SSF47384 591 667 3.14E-7 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 SUPERFAMILY SSF55785 439 574 4.71E-8 T 14-10-2018 IPR035965 PAS domain superfamily D521_1037 a86039ee748b29d0d0b052b7032f716e 844 SUPERFAMILY SSF55785 311 440 1.41E-21 T 14-10-2018 IPR035965 PAS domain superfamily D521_1037 a86039ee748b29d0d0b052b7032f716e 844 Gene3D G3DSA:3.30.450.20 320 441 1.3E-22 T 14-10-2018 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 Gene3D G3DSA:3.30.450.20 446 589 3.0E-6 T 14-10-2018 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 SMART SM00388 598 670 3.3E-5 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 715 836 4.0E-15 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_1037 a86039ee748b29d0d0b052b7032f716e 844 Pfam PF00512 His Kinase A (phospho-acceptor) domain 599 662 8.0E-7 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 Gene3D G3DSA:1.10.287.130 603 667 1.0E-17 T 14-10-2018 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 SUPERFAMILY SSF55874 661 836 6.94E-32 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1037 a86039ee748b29d0d0b052b7032f716e 844 SMART SM00387 712 837 1.9E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_1037 a86039ee748b29d0d0b052b7032f716e 844 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 321 449 2.2E-23 T 14-10-2018 IPR000014 PAS domain D521_1037 a86039ee748b29d0d0b052b7032f716e 844 PRINTS PR00344 Bacterial sensor protein C-terminal signature 780 790 1.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 PRINTS PR00344 Bacterial sensor protein C-terminal signature 762 776 1.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 PRINTS PR00344 Bacterial sensor protein C-terminal signature 791 809 1.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_1037 a86039ee748b29d0d0b052b7032f716e 844 PRINTS PR00344 Bacterial sensor protein C-terminal signature 821 834 1.5E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_2017 d35ecc676479576334f7c040f08d3a99 353 Gene3D G3DSA:3.40.50.300 2 205 7.2E-75 T 14-10-2018 D521_2017 d35ecc676479576334f7c040f08d3a99 353 SUPERFAMILY SSF52540 4 205 2.03E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_2017 d35ecc676479576334f7c040f08d3a99 353 Gene3D G3DSA:3.30.1220.10 230 352 4.9E-32 T 14-10-2018 IPR036627 CobW-like, C-terminal domain superfamily D521_2017 d35ecc676479576334f7c040f08d3a99 353 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 185 8.8E-55 T 14-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain D521_2017 d35ecc676479576334f7c040f08d3a99 353 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 259 352 6.8E-22 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal D521_2017 d35ecc676479576334f7c040f08d3a99 353 SMART SM00833 259 352 7.3E-17 T 14-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal D521_2017 d35ecc676479576334f7c040f08d3a99 353 SUPERFAMILY SSF90002 259 352 3.27E-26 T 14-10-2018 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 SMART SM01192 139 425 1.9E-218 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 PRINTS PR00148 Enolase signature 107 123 1.3E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 PRINTS PR00148 Enolase signature 311 322 1.3E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 PRINTS PR00148 Enolase signature 37 51 1.3E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 PRINTS PR00148 Enolase signature 363 380 1.3E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 PRINTS PR00148 Enolase signature 161 174 1.3E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 PRINTS PR00148 Enolase signature 334 348 1.3E-44 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 Gene3D G3DSA:3.20.20.120 129 428 1.9E-132 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 SUPERFAMILY SSF51604 140 426 1.84E-126 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 424 1.3E-132 T 14-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 SMART SM01193 4 134 2.0E-92 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 425 4.6E-208 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 ProSitePatterns PS00164 Enolase signature. 334 347 - T 14-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 Pfam PF03952 Enolase, N-terminal domain 4 133 1.3E-57 T 14-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 PIRSF PIRSF001400 1 425 9.9E-190 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 Gene3D G3DSA:3.30.390.10 1 127 3.9E-54 T 14-10-2018 IPR029017 Enolase-like, N-terminal D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 Hamap MF_00318 Enolase [eno]. 2 411 44.559 T 14-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 D521_0942 f9d7a8b4862279cf6ac94c28a6986800 428 SUPERFAMILY SSF54826 4 136 5.13E-54 T 14-10-2018 D521_0399 8c82d9d941c08ec1a31e478c7c83771b 187 PIRSF PIRSF000239 1 187 1.7E-44 T 14-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 D521_0399 8c82d9d941c08ec1a31e478c7c83771b 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 3.2E-95 T 14-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 D521_0399 8c82d9d941c08ec1a31e478c7c83771b 187 Pfam PF00578 AhpC/TSA family 9 132 1.5E-28 T 14-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 D521_0399 8c82d9d941c08ec1a31e478c7c83771b 187 SUPERFAMILY SSF52833 3 186 2.75E-51 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0399 8c82d9d941c08ec1a31e478c7c83771b 187 Gene3D G3DSA:3.40.30.10 1 186 2.2E-56 T 14-10-2018 D521_0399 8c82d9d941c08ec1a31e478c7c83771b 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 9.9E-6 T 14-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 D521_1610 a7b4efa0dfdb9ba7a48ecd8cc8fba712 419 Gene3D G3DSA:3.30.9.10 133 361 2.0E-43 T 14-10-2018 D521_1610 a7b4efa0dfdb9ba7a48ecd8cc8fba712 419 SUPERFAMILY SSF54373 269 362 1.83E-10 T 14-10-2018 D521_1610 a7b4efa0dfdb9ba7a48ecd8cc8fba712 419 SUPERFAMILY SSF51905 3 407 2.14E-47 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1610 a7b4efa0dfdb9ba7a48ecd8cc8fba712 419 Gene3D G3DSA:3.50.50.60 105 401 2.0E-43 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1610 a7b4efa0dfdb9ba7a48ecd8cc8fba712 419 Pfam PF01266 FAD dependent oxidoreductase 4 398 1.1E-63 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 D521_1610 a7b4efa0dfdb9ba7a48ecd8cc8fba712 419 Gene3D G3DSA:3.50.50.60 2 67 5.9E-12 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1289 2932270fd9c5cd7faf4b97954ac0bf55 67 SUPERFAMILY SSF88659 20 56 8.04E-11 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like D521_1289 2932270fd9c5cd7faf4b97954ac0bf55 67 Gene3D G3DSA:1.10.10.10 10 61 3.1E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1289 2932270fd9c5cd7faf4b97954ac0bf55 67 Pfam PF04545 Sigma-70, region 4 21 51 5.9E-12 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 D521_1289 2932270fd9c5cd7faf4b97954ac0bf55 67 PRINTS PR00046 Major sigma-70 factor signature 24 39 2.1E-7 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1289 2932270fd9c5cd7faf4b97954ac0bf55 67 PRINTS PR00046 Major sigma-70 factor signature 39 50 2.1E-7 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1878 f63e92f64170f5824697713be6af0e62 352 SUPERFAMILY SSF51735 2 163 4.36E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1878 f63e92f64170f5824697713be6af0e62 352 Gene3D G3DSA:3.40.50.720 3 338 1.1E-122 T 14-10-2018 D521_1878 f63e92f64170f5824697713be6af0e62 352 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 173 323 1.3E-15 T 14-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 D521_1878 f63e92f64170f5824697713be6af0e62 352 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 346 41.407 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 D521_1878 f63e92f64170f5824697713be6af0e62 352 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 352 3.0E-123 T 14-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 D521_1878 f63e92f64170f5824697713be6af0e62 352 Gene3D G3DSA:3.30.360.10 147 320 1.1E-122 T 14-10-2018 D521_1878 f63e92f64170f5824697713be6af0e62 352 SMART SM00859 3 141 2.5E-62 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 D521_1878 f63e92f64170f5824697713be6af0e62 352 SUPERFAMILY SSF55347 149 320 6.28E-45 T 14-10-2018 D521_1878 f63e92f64170f5824697713be6af0e62 352 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 14-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 D521_1878 f63e92f64170f5824697713be6af0e62 352 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 141 3.9E-38 T 14-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 D521_1195 38397346e2d6741d0bf5edd4ac3a0e33 362 SUPERFAMILY SSF117916 3 84 2.03E-15 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily D521_1195 38397346e2d6741d0bf5edd4ac3a0e33 362 SUPERFAMILY SSF52540 88 324 1.23E-60 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1195 38397346e2d6741d0bf5edd4ac3a0e33 362 Gene3D G3DSA:3.40.50.300 89 338 1.9E-88 T 14-10-2018 D521_1195 38397346e2d6741d0bf5edd4ac3a0e33 362 Pfam PF01883 Iron-sulfur cluster assembly protein 6 78 6.1E-20 T 14-10-2018 IPR002744 MIP18 family-like D521_1195 38397346e2d6741d0bf5edd4ac3a0e33 362 Hamap MF_02040 Iron-sulfur cluster carrier protein. 92 340 38.017 T 14-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein D521_1195 38397346e2d6741d0bf5edd4ac3a0e33 362 ProSitePatterns PS01215 Mrp family signature. 203 219 - T 14-10-2018 IPR000808 Mrp, conserved site GO:0005524 D521_1195 38397346e2d6741d0bf5edd4ac3a0e33 362 Gene3D G3DSA:3.30.300.130 3 88 6.1E-7 T 14-10-2018 IPR034904 Fe-S cluster assembly domain superfamily D521_1195 38397346e2d6741d0bf5edd4ac3a0e33 362 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 96 339 1.1E-103 T 14-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 D521_0835 1158bcae7eac284a64890876cd03189b 640 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 630 2.9E-220 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 D521_0835 1158bcae7eac284a64890876cd03189b 640 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 317 528 3.1E-44 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0835 1158bcae7eac284a64890876cd03189b 640 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 633 34.433 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 D521_0835 1158bcae7eac284a64890876cd03189b 640 Gene3D G3DSA:3.30.930.10 222 530 4.7E-127 T 14-10-2018 D521_0835 1158bcae7eac284a64890876cd03189b 640 Gene3D G3DSA:3.30.980.10 69 221 3.3E-66 T 14-10-2018 D521_0835 1158bcae7eac284a64890876cd03189b 640 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 1.0E-14 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 D521_0835 1158bcae7eac284a64890876cd03189b 640 Gene3D G3DSA:3.30.54.20 130 186 3.3E-66 T 14-10-2018 D521_0835 1158bcae7eac284a64890876cd03189b 640 SUPERFAMILY SSF55186 64 240 4.32E-68 T 14-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 D521_0835 1158bcae7eac284a64890876cd03189b 640 Gene3D G3DSA:3.40.50.800 531 637 4.2E-32 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily D521_0835 1158bcae7eac284a64890876cd03189b 640 SUPERFAMILY SSF52954 529 632 3.32E-30 T 14-10-2018 D521_0835 1158bcae7eac284a64890876cd03189b 640 Pfam PF03129 Anticodon binding domain 540 629 8.9E-20 T 14-10-2018 IPR004154 Anticodon-binding D521_0835 1158bcae7eac284a64890876cd03189b 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 506 519 8.2E-54 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 D521_0835 1158bcae7eac284a64890876cd03189b 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 328 356 8.2E-54 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 D521_0835 1158bcae7eac284a64890876cd03189b 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 463 491 8.2E-54 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 D521_0835 1158bcae7eac284a64890876cd03189b 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 361 384 8.2E-54 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 D521_0835 1158bcae7eac284a64890876cd03189b 640 PRINTS PR01047 Threonyl-tRNA synthetase signature 533 545 8.2E-54 T 14-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 D521_0835 1158bcae7eac284a64890876cd03189b 640 SUPERFAMILY SSF81271 3 61 8.28E-15 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 D521_0835 1158bcae7eac284a64890876cd03189b 640 SMART SM00863 169 218 3.5E-24 T 14-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 D521_0835 1158bcae7eac284a64890876cd03189b 640 SUPERFAMILY SSF55681 242 525 1.91E-99 T 14-10-2018 D521_0835 1158bcae7eac284a64890876cd03189b 640 Pfam PF02824 TGS domain 4 61 1.4E-9 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 D521_0835 1158bcae7eac284a64890876cd03189b 640 Gene3D G3DSA:3.10.20.30 1 63 2.2E-19 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_1074 4629562b3e3eac9fd7c44bc686b5b4ca 219 Pfam PF09976 Tetratricopeptide repeat-like domain 15 215 5.5E-47 T 14-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 D521_1074 4629562b3e3eac9fd7c44bc686b5b4ca 219 PIRSF PIRSF006170 1 219 1.8E-47 T 14-10-2018 IPR026039 Uncharacterised protein family UPF0070 D521_2114 815171295bd901e3bc02be64dac73a16 615 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 7 614 49.248 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 D521_2114 815171295bd901e3bc02be64dac73a16 615 PIRSF PIRSF001348 2 615 8.0E-273 T 14-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 D521_2114 815171295bd901e3bc02be64dac73a16 615 Gene3D G3DSA:3.90.228.20 242 612 1.1E-255 T 14-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 D521_2114 815171295bd901e3bc02be64dac73a16 615 SUPERFAMILY SSF53795 242 614 1.05E-144 T 14-10-2018 D521_2114 815171295bd901e3bc02be64dac73a16 615 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 242 613 2.6E-161 T 14-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 D521_2114 815171295bd901e3bc02be64dac73a16 615 Gene3D G3DSA:2.170.8.10 54 406 1.1E-255 T 14-10-2018 D521_2114 815171295bd901e3bc02be64dac73a16 615 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 18 238 6.0E-102 T 14-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 D521_2114 815171295bd901e3bc02be64dac73a16 615 Gene3D G3DSA:3.40.449.10 18 241 1.1E-255 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 D521_2114 815171295bd901e3bc02be64dac73a16 615 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 266 274 - T 14-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 D521_2114 815171295bd901e3bc02be64dac73a16 615 SUPERFAMILY SSF68923 8 241 5.18E-100 T 14-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 D521_0155 b45855334f51f5dae90f063718b789d3 397 SUPERFAMILY SSF53187 8 396 1.31E-87 T 14-10-2018 D521_0155 b45855334f51f5dae90f063718b789d3 397 Gene3D G3DSA:3.40.630.10 16 379 7.8E-138 T 14-10-2018 D521_0155 b45855334f51f5dae90f063718b789d3 397 Pfam PF01546 Peptidase family M20/M25/M40 74 392 6.4E-37 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 D521_0155 b45855334f51f5dae90f063718b789d3 397 Pfam PF07687 Peptidase dimerisation domain 186 281 3.5E-10 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain D521_0155 b45855334f51f5dae90f063718b789d3 397 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 15 383 4.1E-114 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 D521_0155 b45855334f51f5dae90f063718b789d3 397 SUPERFAMILY SSF55031 185 291 5.5E-31 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain D521_0155 b45855334f51f5dae90f063718b789d3 397 PIRSF PIRSF005962 4 397 4.6E-132 T 14-10-2018 IPR017439 Amidohydrolase GO:0016787 D521_0155 b45855334f51f5dae90f063718b789d3 397 Gene3D G3DSA:3.30.70.360 182 296 7.8E-138 T 14-10-2018 D521_0064 01c7e7a6933341a3df4b45fa6771d36c 180 ProSitePatterns PS00358 Ribosomal protein L5 signature. 58 74 - T 14-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0064 01c7e7a6933341a3df4b45fa6771d36c 180 SUPERFAMILY SSF55282 4 180 4.47E-76 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0064 01c7e7a6933341a3df4b45fa6771d36c 180 Pfam PF00281 Ribosomal protein L5 25 81 4.4E-26 T 14-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0064 01c7e7a6933341a3df4b45fa6771d36c 180 Pfam PF00673 ribosomal L5P family C-terminus 85 178 1.3E-39 T 14-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0064 01c7e7a6933341a3df4b45fa6771d36c 180 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 2 180 43.469 T 14-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0064 01c7e7a6933341a3df4b45fa6771d36c 180 Gene3D G3DSA:3.30.1440.10 1 180 7.8E-78 T 14-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0064 01c7e7a6933341a3df4b45fa6771d36c 180 PIRSF PIRSF002161 1 180 1.5E-63 T 14-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 9 327 1.9E-113 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 SMART SM00864 15 204 7.2E-99 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 Gene3D G3DSA:3.30.1330.20 220 331 1.8E-33 T 14-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 Gene3D G3DSA:3.40.50.1440 5 218 8.6E-70 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 PRINTS PR00423 Cell division protein FtsZ signature 125 146 7.2E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 PRINTS PR00423 Cell division protein FtsZ signature 211 232 7.2E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 PRINTS PR00423 Cell division protein FtsZ signature 97 117 7.2E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 PRINTS PR00423 Cell division protein FtsZ signature 188 210 7.2E-46 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 Pfam PF12327 FtsZ family, C-terminal domain 221 315 4.9E-30 T 14-10-2018 IPR024757 Cell division protein FtsZ, C-terminal D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 ProSitePatterns PS01135 FtsZ protein signature 2. 96 117 - T 14-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 16 172 4.8E-34 T 14-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 11 372 34.545 T 14-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 SUPERFAMILY SSF52490 16 207 5.89E-60 T 14-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 SMART SM00865 206 324 2.9E-52 T 14-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 D521_0175 50bfdcd1c5aa2a1de5bd6c8ce60facf2 446 SUPERFAMILY SSF55307 204 319 8.01E-39 T 14-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 D521_1127 fc45a8d99113db86826ae70cff1d829f 341 Pfam PF12727 PBP superfamily domain 147 315 2.0E-48 T 14-10-2018 IPR024370 PBP domain D521_1127 fc45a8d99113db86826ae70cff1d829f 341 SUPERFAMILY SSF46785 29 96 5.99E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1127 fc45a8d99113db86826ae70cff1d829f 341 Gene3D G3DSA:3.40.190.10 148 196 1.6E-8 T 14-10-2018 D521_1127 fc45a8d99113db86826ae70cff1d829f 341 SUPERFAMILY SSF53850 145 296 5.67E-12 T 14-10-2018 D521_1127 fc45a8d99113db86826ae70cff1d829f 341 Gene3D G3DSA:1.10.10.10 15 123 1.5E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1127 fc45a8d99113db86826ae70cff1d829f 341 Gene3D G3DSA:3.40.190.10 197 291 1.6E-8 T 14-10-2018 D521_1127 fc45a8d99113db86826ae70cff1d829f 341 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 35 84 2.7E-7 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 157 164 - T 14-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 SUPERFAMILY SSF54719 81 191 3.67E-45 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 2 82 7.1E-35 T 14-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 SUPERFAMILY SSF46609 1 84 2.49E-36 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 89 189 4.4E-40 T 14-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 Gene3D G3DSA:1.10.287.990 20 81 3.8E-27 T 14-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 PIRSF PIRSF000349 1 192 1.3E-89 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 Gene3D G3DSA:2.40.500.20 83 192 1.8E-44 T 14-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 PRINTS PR01703 Manganese superoxide dismutase signature 65 78 4.2E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 4.2E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 PRINTS PR01703 Manganese superoxide dismutase signature 118 126 4.2E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 PRINTS PR01703 Manganese superoxide dismutase signature 155 167 4.2E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_1164 109b8a9d6bb96aa2c088cafe0dc532f0 192 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 4.2E-22 T 14-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 D521_2066 5d4e7943674f1d3dab6fbf11019e695c 95 SUPERFAMILY SSF46626 3 93 3.24E-18 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_2066 5d4e7943674f1d3dab6fbf11019e695c 95 Gene3D G3DSA:1.10.760.10 8 95 2.9E-31 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_2066 5d4e7943674f1d3dab6fbf11019e695c 95 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 12 87 4.8E-14 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_2066 5d4e7943674f1d3dab6fbf11019e695c 95 PRINTS PR00605 Class IC cytochrome C signature 26 37 3.3E-6 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 D521_2066 5d4e7943674f1d3dab6fbf11019e695c 95 PRINTS PR00605 Class IC cytochrome C signature 65 87 3.3E-6 T 14-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 D521_1846 4ac26c070b27af8247353a0c83f8f339 174 SUPERFAMILY SSF51161 7 170 1.03E-46 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily D521_1846 4ac26c070b27af8247353a0c83f8f339 174 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 122 7.4E-10 T 14-10-2018 IPR001451 Hexapeptide repeat D521_1846 4ac26c070b27af8247353a0c83f8f339 174 Gene3D G3DSA:2.160.10.10 1 173 2.2E-61 T 14-10-2018 D521_0939 af776a89a097772eaf300506e59ab646 861 Gene3D G3DSA:1.25.40.310 1 161 2.8E-65 T 14-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 D521_0939 af776a89a097772eaf300506e59ab646 861 SUPERFAMILY SSF53732 378 853 2.49E-144 T 14-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 D521_0939 af776a89a097772eaf300506e59ab646 861 SUPERFAMILY SSF74778 1 160 6.02E-64 T 14-10-2018 IPR036288 Aconitase B, HEAT-like domain superfamily GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 D521_0939 af776a89a097772eaf300506e59ab646 861 Gene3D G3DSA:3.30.499.10 403 530 6.2E-147 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 D521_0939 af776a89a097772eaf300506e59ab646 861 Gene3D G3DSA:3.40.1060.10 383 682 6.2E-147 T 14-10-2018 IPR015932 Aconitase, domain 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-1268020|Reactome: R-HSA-71403 D521_0939 af776a89a097772eaf300506e59ab646 861 Pfam PF11791 Aconitate B N-terminal domain 4 156 4.6E-62 T 14-10-2018 IPR015933 Aconitase B, HEAT-like domain GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 D521_0939 af776a89a097772eaf300506e59ab646 861 Pfam PF00330 Aconitase family (aconitate hydratase) 470 818 1.3E-39 T 14-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 D521_0939 af776a89a097772eaf300506e59ab646 861 Pfam PF06434 Aconitate hydratase 2 N-terminus 168 380 9.9E-94 T 14-10-2018 IPR015929 Aconitase B, swivel GO:0003994|GO:0006099 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 D521_0939 af776a89a097772eaf300506e59ab646 861 SUPERFAMILY SSF52016 162 369 4.91E-65 T 14-10-2018 D521_0939 af776a89a097772eaf300506e59ab646 861 Gene3D G3DSA:3.20.19.10 162 359 6.9E-74 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 D521_0939 af776a89a097772eaf300506e59ab646 861 PIRSF PIRSF036687 1 859 0.0 T 14-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 D521_0939 af776a89a097772eaf300506e59ab646 861 TIGRFAM TIGR00117 acnB: aconitate hydratase 2 1 853 0.0 T 14-10-2018 IPR004406 Aconitase B GO:0003994|GO:0005829|GO:0006099|GO:0051539 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00640+4.2.1.99|KEGG: 00720+4.2.1.3|MetaCyc: PWY-5747 D521_0939 af776a89a097772eaf300506e59ab646 861 ProSitePatterns PS00450 Aconitase family signature 1. 703 720 - T 14-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 D521_0939 af776a89a097772eaf300506e59ab646 861 Gene3D G3DSA:3.30.499.10 684 861 3.9E-63 T 14-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 SUPERFAMILY SSF56784 481 767 3.88E-41 T 14-10-2018 IPR036412 HAD-like superfamily D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 Pfam PF00403 Heavy-metal-associated domain 64 125 7.1E-6 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 Pfam PF00702 haloacid dehalogenase-like hydrolase 481 682 3.8E-28 T 14-10-2018 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 198 771 1.6E-122 T 14-10-2018 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 254 747 1.3E-59 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 484 490 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 Gene3D G3DSA:3.40.50.1000 463 720 1.2E-53 T 14-10-2018 IPR023214 HAD superfamily D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 SUPERFAMILY SSF55008 59 130 1.1E-14 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 Gene3D G3DSA:3.30.70.100 61 130 1.1E-11 T 14-10-2018 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 482 496 1.5E-19 T 14-10-2018 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 691 703 1.5E-19 T 14-10-2018 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 334 348 1.5E-19 T 14-10-2018 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 615 625 1.5E-19 T 14-10-2018 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 668 687 1.5E-19 T 14-10-2018 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 Pfam PF00122 E1-E2 ATPase 283 460 1.1E-39 T 14-10-2018 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 219 770 8.8E-133 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 SUPERFAMILY SSF81653 296 383 1.09E-20 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 Gene3D G3DSA:2.70.150.20 275 388 1.0E-26 T 14-10-2018 D521_1530 d531e1f784c5a8413f1a8c9ab9daf6e5 773 Gene3D G3DSA:3.40.1110.10 493 600 1.2E-53 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 29 665 3.7E-182 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 Pfam PF08264 Anticodon-binding domain of tRNA 710 868 9.8E-27 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 SUPERFAMILY SSF50677 204 412 6.8E-46 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 60 71 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 410 425 5.0E-26 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 240 263 5.0E-26 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 586 595 5.0E-26 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 53 64 5.0E-26 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 4 944 20.166 T 14-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 SUPERFAMILY SSF52374 10 674 1.97E-124 T 14-10-2018 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 Pfam PF06827 Zinc finger found in FPG and IleRS 914 941 3.5E-8 T 14-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 Gene3D G3DSA:3.90.740.10 194 417 6.9E-217 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 SUPERFAMILY SSF47323 677 943 3.18E-69 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 17 869 7.6E-264 T 14-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 Gene3D G3DSA:1.10.730.20 665 943 1.0E-87 T 14-10-2018 D521_1725 aa0835cec9164e763061ea8568c8fcc3 953 Gene3D G3DSA:3.40.50.620 27 654 6.9E-217 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1403 67d7d73b26723912d37596b3f378bf49 358 PIRSF PIRSF500176 10 345 2.7E-46 T 14-10-2018 D521_1403 67d7d73b26723912d37596b3f378bf49 358 Gene3D G3DSA:3.40.50.40 233 340 2.3E-22 T 14-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 D521_1403 67d7d73b26723912d37596b3f378bf49 358 PRINTS PR00139 Asparaginase/glutaminase family signature 96 114 3.9E-17 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 D521_1403 67d7d73b26723912d37596b3f378bf49 358 PRINTS PR00139 Asparaginase/glutaminase family signature 14 25 3.9E-17 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 D521_1403 67d7d73b26723912d37596b3f378bf49 358 PRINTS PR00139 Asparaginase/glutaminase family signature 280 298 3.9E-17 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 D521_1403 67d7d73b26723912d37596b3f378bf49 358 SMART SM00870 13 339 1.3E-57 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 D521_1403 67d7d73b26723912d37596b3f378bf49 358 SUPERFAMILY SSF53774 9 337 5.89E-60 T 14-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 D521_1403 67d7d73b26723912d37596b3f378bf49 358 Gene3D G3DSA:3.40.50.1170 7 213 7.0E-45 T 14-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 D521_1403 67d7d73b26723912d37596b3f378bf49 358 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 97 107 - T 14-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 D521_1403 67d7d73b26723912d37596b3f378bf49 358 Pfam PF00710 Asparaginase, N-terminal 14 205 1.1E-37 T 14-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 D521_1403 67d7d73b26723912d37596b3f378bf49 358 PIRSF PIRSF001220 8 345 7.2E-50 T 14-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 204 217 2.1E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 385 398 2.1E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 91 103 2.1E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 71 89 2.1E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 287 306 2.1E-24 T 14-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 56 296 3.1E-68 T 14-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 Gene3D G3DSA:3.20.20.10 44 292 1.0E-149 T 14-10-2018 IPR029066 PLP-binding barrel D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 Gene3D G3DSA:2.40.37.10 24 425 1.0E-149 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 17 427 7.3E-156 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 PRINTS PR01181 Diaminopimelate decarboxylase signature 178 187 2.0E-26 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 PRINTS PR01181 Diaminopimelate decarboxylase signature 395 417 2.0E-26 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 PRINTS PR01181 Diaminopimelate decarboxylase signature 89 106 2.0E-26 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 PRINTS PR01181 Diaminopimelate decarboxylase signature 315 333 2.0E-26 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 40 385 2.4E-27 T 14-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 SUPERFAMILY SSF50621 277 429 2.3E-51 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 25 428 41.221 T 14-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 242 255 - T 14-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site D521_0085 8ae37f3ab67b5332b27fc6d3141eca8d 432 SUPERFAMILY SSF51419 36 299 7.33E-78 T 14-10-2018 IPR029066 PLP-binding barrel D521_0070 edb6777167cdab97aad650431cf853ce 62 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 8 61 1.7E-23 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0070 edb6777167cdab97aad650431cf853ce 62 Pfam PF00327 Ribosomal protein L30p/L7e 11 58 5.1E-17 T 14-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain D521_0070 edb6777167cdab97aad650431cf853ce 62 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 4 62 19.386 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0070 edb6777167cdab97aad650431cf853ce 62 Gene3D G3DSA:3.30.1390.20 5 61 2.9E-23 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily D521_0070 edb6777167cdab97aad650431cf853ce 62 SUPERFAMILY SSF55129 7 60 8.5E-19 T 14-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily D521_0070 edb6777167cdab97aad650431cf853ce 62 PIRSF PIRSF002211 2 62 2.2E-25 T 14-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1582 5938c64bddb5b6911c19f519e6c8a6aa 394 Gene3D G3DSA:3.40.50.10540 5 388 8.1E-111 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_1582 5938c64bddb5b6911c19f519e6c8a6aa 394 Pfam PF02515 CoA-transferase family III 6 370 2.6E-102 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 D521_1582 5938c64bddb5b6911c19f519e6c8a6aa 394 Gene3D G3DSA:3.30.1540.10 231 324 8.1E-111 T 14-10-2018 D521_1582 5938c64bddb5b6911c19f519e6c8a6aa 394 SUPERFAMILY SSF89796 4 394 2.75E-117 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_1394 b7bdee3556ee32bddac3759f556a8f77 557 Gene3D G3DSA:3.40.50.1010 93 246 3.6E-24 T 14-10-2018 D521_1394 b7bdee3556ee32bddac3759f556a8f77 557 Pfam PF02562 PhoH-like protein 344 553 1.7E-54 T 14-10-2018 IPR003714 PhoH-like protein GO:0005524 D521_1394 b7bdee3556ee32bddac3759f556a8f77 557 SUPERFAMILY SSF52540 343 535 6.34E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1394 b7bdee3556ee32bddac3759f556a8f77 557 SMART SM00670 96 231 4.5E-11 T 14-10-2018 IPR002716 PIN domain D521_1394 b7bdee3556ee32bddac3759f556a8f77 557 SUPERFAMILY SSF88723 95 246 4.9E-12 T 14-10-2018 IPR029060 PIN-like domain superfamily D521_1394 b7bdee3556ee32bddac3759f556a8f77 557 Pfam PF13638 PIN domain 98 243 1.7E-38 T 14-10-2018 IPR002716 PIN domain D521_1394 b7bdee3556ee32bddac3759f556a8f77 557 Gene3D G3DSA:3.40.50.300 341 556 1.0E-66 T 14-10-2018 D521_1861 7ee90afa7cb6220d99a71d95af0a9e0e 259 SUPERFAMILY SSF53335 3 256 3.98E-63 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1861 7ee90afa7cb6220d99a71d95af0a9e0e 259 SMART SM00650 19 193 1.1E-70 T 14-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 D521_1861 7ee90afa7cb6220d99a71d95af0a9e0e 259 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 35 62 - T 14-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 D521_1861 7ee90afa7cb6220d99a71d95af0a9e0e 259 Gene3D G3DSA:1.10.8.100 199 259 4.4E-13 T 14-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 D521_1861 7ee90afa7cb6220d99a71d95af0a9e0e 259 Gene3D G3DSA:3.40.50.150 1 194 7.3E-60 T 14-10-2018 D521_1861 7ee90afa7cb6220d99a71d95af0a9e0e 259 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 3 254 1.8E-75 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 D521_1861 7ee90afa7cb6220d99a71d95af0a9e0e 259 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 3 258 49.541 T 14-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 D521_1861 7ee90afa7cb6220d99a71d95af0a9e0e 259 Pfam PF00398 Ribosomal RNA adenine dimethylase 3 257 6.1E-59 T 14-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 Gene3D G3DSA:3.50.50.60 8 311 1.3E-97 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 1.5E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 1.5E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 65 75 1.5E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 1.5E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 279 297 1.5E-18 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 298 2.2E-25 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 Hamap MF_01685 Ferredoxin--NADP reductase. 6 332 41.644 T 14-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 SUPERFAMILY SSF51905 8 319 1.18E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 Gene3D G3DSA:3.50.50.60 128 249 1.3E-97 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 6.0E-14 T 14-10-2018 D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 6.0E-14 T 14-10-2018 D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 6.0E-14 T 14-10-2018 D521_1445 90d8cb15057120ddfdb7b1dc7f4e7782 343 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 6.0E-14 T 14-10-2018 D521_1387 5618645a61ef4391661e82ea17f1100b 564 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 71 232 3.8E-15 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like D521_1987 fb5229c35e9b5da8caa2391233e7c4d3 443 Gene3D G3DSA:1.10.287.470 170 229 4.0E-69 T 14-10-2018 D521_1987 fb5229c35e9b5da8caa2391233e7c4d3 443 Gene3D G3DSA:2.40.30.170 125 346 4.0E-69 T 14-10-2018 D521_1987 fb5229c35e9b5da8caa2391233e7c4d3 443 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 136 336 8.3E-31 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain D521_1987 fb5229c35e9b5da8caa2391233e7c4d3 443 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 111 424 7.7E-66 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 D521_1987 fb5229c35e9b5da8caa2391233e7c4d3 443 Pfam PF00529 HlyD membrane-fusion protein of T1SS 22 412 8.5E-7 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 D521_1987 fb5229c35e9b5da8caa2391233e7c4d3 443 SUPERFAMILY SSF111369 127 343 1.24E-43 T 14-10-2018 D521_1987 fb5229c35e9b5da8caa2391233e7c4d3 443 Gene3D G3DSA:2.40.420.20 347 423 4.0E-69 T 14-10-2018 D521_1987 fb5229c35e9b5da8caa2391233e7c4d3 443 Gene3D G3DSA:2.40.50.100 135 263 4.0E-69 T 14-10-2018 D521_1404 aaeca732b2a29694fab3910a9d343591 239 Pfam PF00717 Peptidase S24-like 148 197 2.6E-13 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C D521_1404 aaeca732b2a29694fab3910a9d343591 239 TIGRFAM TIGR00498 lexA: repressor LexA 17 236 4.7E-69 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 D521_1404 aaeca732b2a29694fab3910a9d343591 239 Pfam PF01726 LexA DNA binding domain 17 79 8.0E-26 T 14-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 D521_1404 aaeca732b2a29694fab3910a9d343591 239 SUPERFAMILY SSF46785 17 83 8.29E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1404 aaeca732b2a29694fab3910a9d343591 239 Gene3D G3DSA:2.10.109.10 114 238 1.8E-39 T 14-10-2018 D521_1404 aaeca732b2a29694fab3910a9d343591 239 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 184 196 7.2E-11 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 D521_1404 aaeca732b2a29694fab3910a9d343591 239 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 156 167 7.2E-11 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 D521_1404 aaeca732b2a29694fab3910a9d343591 239 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 145 155 7.2E-11 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 D521_1404 aaeca732b2a29694fab3910a9d343591 239 SUPERFAMILY SSF51306 109 235 1.57E-33 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily D521_1404 aaeca732b2a29694fab3910a9d343591 239 Hamap MF_00015 LexA repressor [lexA]. 17 237 31.032 T 14-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 D521_1404 aaeca732b2a29694fab3910a9d343591 239 Gene3D G3DSA:1.10.10.10 15 83 7.9E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1457 88927e28f6ec51bebeb9cce977f9bde9 187 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 9 187 22.253 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 D521_1457 88927e28f6ec51bebeb9cce977f9bde9 187 Pfam PF05239 PRC-barrel domain 113 181 2.7E-5 T 14-10-2018 IPR027275 PRC-barrel domain D521_1457 88927e28f6ec51bebeb9cce977f9bde9 187 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 10 186 8.9E-37 T 14-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 D521_1457 88927e28f6ec51bebeb9cce977f9bde9 187 SUPERFAMILY SSF50447 8 109 2.15E-14 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily D521_1457 88927e28f6ec51bebeb9cce977f9bde9 187 Gene3D G3DSA:2.30.30.240 110 187 4.9E-22 T 14-10-2018 D521_1457 88927e28f6ec51bebeb9cce977f9bde9 187 Pfam PF01782 RimM N-terminal domain 11 105 2.1E-22 T 14-10-2018 IPR002676 RimM, N-terminal GO:0006364 D521_1457 88927e28f6ec51bebeb9cce977f9bde9 187 Gene3D G3DSA:2.40.30.60 2 109 6.1E-21 T 14-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 D521_1457 88927e28f6ec51bebeb9cce977f9bde9 187 SUPERFAMILY SSF50346 115 186 2.55E-16 T 14-10-2018 IPR011033 PRC-barrel-like superfamily D521_0792 a42b08a896032ab9e32712d08d9b38af 237 SUPERFAMILY SSF52172 2 127 2.7E-40 T 14-10-2018 IPR011006 CheY-like superfamily D521_0792 a42b08a896032ab9e32712d08d9b38af 237 SMART SM00862 155 230 2.8E-24 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 D521_0792 a42b08a896032ab9e32712d08d9b38af 237 SMART SM00448 3 116 8.1E-42 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_0792 a42b08a896032ab9e32712d08d9b38af 237 Pfam PF00072 Response regulator receiver domain 5 117 9.6E-26 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_0792 a42b08a896032ab9e32712d08d9b38af 237 SUPERFAMILY SSF46894 128 230 4.35E-27 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 D521_0792 a42b08a896032ab9e32712d08d9b38af 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 230 6.1E-26 T 14-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 D521_0792 a42b08a896032ab9e32712d08d9b38af 237 Gene3D G3DSA:3.40.50.2300 1 127 2.3E-37 T 14-10-2018 D521_0792 a42b08a896032ab9e32712d08d9b38af 237 Gene3D G3DSA:1.10.10.10 128 233 4.5E-32 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0792 a42b08a896032ab9e32712d08d9b38af 237 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 1 230 7.4E-97 T 14-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 Pfam PF08448 PAS fold 206 312 5.3E-11 T 14-10-2018 IPR013656 PAS fold-4 D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 Gene3D G3DSA:1.10.1760.20 35 192 3.5E-5 T 14-10-2018 D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 SMART SM00267 311 487 3.1E-47 T 14-10-2018 IPR000160 GGDEF domain D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 SMART SM00052 497 743 4.2E-103 T 14-10-2018 IPR001633 EAL domain D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 Pfam PF07694 5TMR of 5TMR-LYT 31 178 3.1E-19 T 14-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 198 315 1.3E-7 T 14-10-2018 IPR000014 PAS domain D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 Gene3D G3DSA:3.30.70.270 316 500 1.3E-45 T 14-10-2018 D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 Pfam PF00990 Diguanylate cyclase, GGDEF domain 322 482 6.8E-36 T 14-10-2018 IPR000160 GGDEF domain D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 SMART SM00091 198 264 9.3E-4 T 14-10-2018 IPR000014 PAS domain D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 320 485 2.4E-28 T 14-10-2018 IPR000160 GGDEF domain D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 SUPERFAMILY SSF55073 327 489 4.32E-37 T 14-10-2018 IPR029787 Nucleotide cyclase D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 SUPERFAMILY SSF55785 189 309 4.34E-12 T 14-10-2018 IPR035965 PAS domain superfamily D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 Pfam PF00563 EAL domain 503 738 6.1E-73 T 14-10-2018 IPR001633 EAL domain D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 SUPERFAMILY SSF141868 502 743 1.7E-83 T 14-10-2018 IPR035919 EAL domain superfamily D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 Gene3D G3DSA:3.30.450.20 193 310 2.5E-14 T 14-10-2018 D521_0628 2f36d64b4616294c692331fc54eb8d6e 745 Gene3D G3DSA:3.20.20.450 501 745 1.5E-91 T 14-10-2018 IPR035919 EAL domain superfamily D521_1020 94c2ee23e58f8f63121757212f2c49eb 284 Gene3D G3DSA:3.40.50.720 1 188 7.1E-73 T 14-10-2018 D521_1020 94c2ee23e58f8f63121757212f2c49eb 284 SUPERFAMILY SSF51735 1 185 1.68E-60 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1020 94c2ee23e58f8f63121757212f2c49eb 284 PIRSF PIRSF000105 1 284 5.6E-91 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 D521_1020 94c2ee23e58f8f63121757212f2c49eb 284 SUPERFAMILY SSF48179 185 283 1.11E-33 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_1020 94c2ee23e58f8f63121757212f2c49eb 284 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 183 207 - T 14-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 D521_1020 94c2ee23e58f8f63121757212f2c49eb 284 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 6 183 3.3E-66 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 D521_1020 94c2ee23e58f8f63121757212f2c49eb 284 Gene3D G3DSA:1.10.1040.10 189 284 1.1E-34 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 D521_1020 94c2ee23e58f8f63121757212f2c49eb 284 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 2.9E-35 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 D521_1385 097d74abc6f9b8260cb88948aa8d37fc 392 Gene3D G3DSA:3.90.1150.10 1 371 2.1E-140 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_1385 097d74abc6f9b8260cb88948aa8d37fc 392 Pfam PF00155 Aminotransferase class I and II 9 368 1.5E-54 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 D521_1385 097d74abc6f9b8260cb88948aa8d37fc 392 Gene3D G3DSA:3.40.640.10 26 267 2.1E-140 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_1385 097d74abc6f9b8260cb88948aa8d37fc 392 SUPERFAMILY SSF53383 3 374 6.18E-95 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0619 fc4a472397664f555571005c8c63bcfd 109 SUPERFAMILY SSF46785 4 93 4.08E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0619 fc4a472397664f555571005c8c63bcfd 109 SMART SM00418 9 85 2.4E-8 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0619 fc4a472397664f555571005c8c63bcfd 109 Pfam PF12840 Helix-turn-helix domain 12 69 4.7E-12 T 14-10-2018 D521_0619 fc4a472397664f555571005c8c63bcfd 109 Gene3D G3DSA:1.10.10.10 1 93 1.1E-16 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0665 77323d6ea674bd6f93ede560d7e67026 435 Gene3D G3DSA:3.40.50.300 7 163 1.1E-31 T 14-10-2018 D521_0665 77323d6ea674bd6f93ede560d7e67026 435 Pfam PF05970 PIF1-like helicase 11 155 1.4E-29 T 14-10-2018 IPR010285 DNA helicase Pif1-like GO:0000723|GO:0003678|GO:0006281 D521_0665 77323d6ea674bd6f93ede560d7e67026 435 SUPERFAMILY SSF52540 129 432 6.64E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0665 77323d6ea674bd6f93ede560d7e67026 435 Pfam PF02689 Helicase 366 411 2.5E-5 T 14-10-2018 IPR003840 DNA helicase GO:0004386|GO:0005524 D521_0665 77323d6ea674bd6f93ede560d7e67026 435 SUPERFAMILY SSF52540 5 148 1.11E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1909 e356d21a40a7fd9b707c2b43840dcf83 152 SUPERFAMILY SSF55804 4 147 5.49E-36 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 D521_1909 e356d21a40a7fd9b707c2b43840dcf83 152 Gene3D G3DSA:3.40.930.10 1 151 1.5E-46 T 14-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 D521_1909 e356d21a40a7fd9b707c2b43840dcf83 152 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 14-10-2018 IPR002178 PTS EIIA type-2 domain D521_1909 e356d21a40a7fd9b707c2b43840dcf83 152 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 147 1.9E-33 T 14-10-2018 IPR002178 PTS EIIA type-2 domain D521_1563 fd5bdb906396dc61d09cf34487e0a934 134 SUPERFAMILY SSF53137 5 105 2.81E-13 T 14-10-2018 D521_1563 fd5bdb906396dc61d09cf34487e0a934 134 Gene3D G3DSA:3.30.420.60 5 110 5.0E-7 T 14-10-2018 D521_0749 82afd4f745b600358df310ee80baf515 417 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 417 49.603 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0749 82afd4f745b600358df310ee80baf515 417 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 417 1.7E-184 T 14-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0749 82afd4f745b600358df310ee80baf515 417 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 417 1.5E-122 T 14-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0749 82afd4f745b600358df310ee80baf515 417 Gene3D G3DSA:1.10.645.20 4 417 1.3E-171 T 14-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0749 82afd4f745b600358df310ee80baf515 417 SUPERFAMILY SSF56762 16 417 4.71E-137 T 14-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0749 82afd4f745b600358df310ee80baf515 417 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 14-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 SUPERFAMILY SSF56003 43 255 2.34E-36 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 52 194 2.1E-11 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 327 568 4.5E-31 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 607 687 2.9E-10 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 Gene3D G3DSA:3.30.365.10 330 567 6.9E-57 T 14-10-2018 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 Gene3D G3DSA:3.30.365.10 354 447 6.9E-57 T 14-10-2018 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 PIRSF PIRSF036389 1 740 8.7E-213 T 14-10-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 SUPERFAMILY SSF56003 328 737 2.56E-100 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 Gene3D G3DSA:3.30.365.10 52 192 4.8E-20 T 14-10-2018 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 Gene3D G3DSA:3.90.1170.50 193 275 2.8E-13 T 14-10-2018 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 222 273 1.1E-4 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 Gene3D G3DSA:3.30.365.10 595 740 3.6E-30 T 14-10-2018 D521_0674 87940cc2f39926c555bf8b09f3e516b0 741 SMART SM01008 222 301 5.5E-22 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 SUPERFAMILY SSF48256 16 434 1.2E-161 T 14-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 Gene3D G3DSA:1.10.230.10 272 384 7.7E-143 T 14-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 ProSitePatterns PS00480 Citrate synthase signature. 310 322 - T 14-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 18 429 4.4E-236 T 14-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 Gene3D G3DSA:1.10.580.10 61 419 7.7E-143 T 14-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 Gene3D G3DSA:2.20.28.60 1 54 3.9E-23 T 14-10-2018 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 Pfam PF00285 Citrate synthase, C-terminal domain 52 419 2.3E-132 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 PIRSF PIRSF001369 41 437 1.9E-160 T 14-10-2018 IPR024176 Citrate synthase, bacterial-type D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 PRINTS PR00143 Citrate synthase signature 169 182 1.1E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 PRINTS PR00143 Citrate synthase signature 303 323 1.1E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 PRINTS PR00143 Citrate synthase signature 367 383 1.1E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 PRINTS PR00143 Citrate synthase signature 245 273 1.1E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 PRINTS PR00143 Citrate synthase signature 223 238 1.1E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 D521_1007 9d1722b519fa15c0e8f9c5aedc114c07 437 PRINTS PR00143 Citrate synthase signature 387 401 1.1E-53 T 14-10-2018 IPR002020 Citrate synthase GO:0046912 D521_2112 25bf36f777c56273264d86feaa304bd5 892 Gene3D G3DSA:1.10.460.10 178 633 7.9E-158 T 14-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 D521_2112 25bf36f777c56273264d86feaa304bd5 892 SMART SM00437 297 585 3.2E-70 T 14-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 D521_2112 25bf36f777c56273264d86feaa304bd5 892 Gene3D G3DSA:1.10.290.10 306 448 7.9E-158 T 14-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 D521_2112 25bf36f777c56273264d86feaa304bd5 892 Pfam PF01751 Toprim domain 23 150 9.9E-13 T 14-10-2018 IPR006171 TOPRIM domain D521_2112 25bf36f777c56273264d86feaa304bd5 892 Pfam PF01131 DNA topoisomerase 172 624 5.0E-117 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 D521_2112 25bf36f777c56273264d86feaa304bd5 892 Gene3D G3DSA:3.40.50.140 22 171 1.1E-45 T 14-10-2018 D521_2112 25bf36f777c56273264d86feaa304bd5 892 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 340 349 5.0E-27 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 D521_2112 25bf36f777c56273264d86feaa304bd5 892 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 118 131 5.0E-27 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 D521_2112 25bf36f777c56273264d86feaa304bd5 892 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 209 227 5.0E-27 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 D521_2112 25bf36f777c56273264d86feaa304bd5 892 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 434 450 5.0E-27 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 D521_2112 25bf36f777c56273264d86feaa304bd5 892 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 548 562 5.0E-27 T 14-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 D521_2112 25bf36f777c56273264d86feaa304bd5 892 SUPERFAMILY SSF56712 21 638 6.67E-171 T 14-10-2018 IPR023405 DNA topoisomerase, type IA, core domain D521_2112 25bf36f777c56273264d86feaa304bd5 892 Pfam PF13342 C-terminal repeat of topoisomerase 790 850 1.5E-18 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat D521_2112 25bf36f777c56273264d86feaa304bd5 892 Pfam PF13342 C-terminal repeat of topoisomerase 674 743 1.8E-18 T 14-10-2018 IPR025589 Topoisomerase C-terminal repeat D521_2112 25bf36f777c56273264d86feaa304bd5 892 Gene3D G3DSA:2.70.20.10 233 516 7.9E-158 T 14-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 D521_2112 25bf36f777c56273264d86feaa304bd5 892 SMART SM00493 21 144 1.5E-16 T 14-10-2018 IPR006171 TOPRIM domain D521_2112 25bf36f777c56273264d86feaa304bd5 892 TIGRFAM TIGR01056 topB: DNA topoisomerase III 21 653 1.5E-168 T 14-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 D521_2112 25bf36f777c56273264d86feaa304bd5 892 SMART SM00436 144 239 8.5E-22 T 14-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 D521_2112 25bf36f777c56273264d86feaa304bd5 892 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 334 349 - T 14-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 D521_0059 352dad26b98c1cb1ae8b0d56c45ffa3e 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.0E-38 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0059 352dad26b98c1cb1ae8b0d56c45ffa3e 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.0E-38 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0059 352dad26b98c1cb1ae8b0d56c45ffa3e 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.0E-38 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0059 352dad26b98c1cb1ae8b0d56c45ffa3e 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.0E-38 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0059 352dad26b98c1cb1ae8b0d56c45ffa3e 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 126 7.0E-59 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0059 352dad26b98c1cb1ae8b0d56c45ffa3e 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.178 T 14-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0059 352dad26b98c1cb1ae8b0d56c45ffa3e 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 14-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0059 352dad26b98c1cb1ae8b0d56c45ffa3e 137 SUPERFAMILY SSF54686 1 134 7.33E-53 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 D521_0059 352dad26b98c1cb1ae8b0d56c45ffa3e 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 7.5E-48 T 14-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 D521_0059 352dad26b98c1cb1ae8b0d56c45ffa3e 137 Gene3D G3DSA:3.90.1170.10 1 136 2.1E-54 T 14-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 D521_2053 311cdf154ddd565678f73a73cf1578dc 201 SUPERFAMILY SSF55729 7 181 3.83E-32 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_2053 311cdf154ddd565678f73a73cf1578dc 201 Gene3D G3DSA:3.40.630.30 1 197 8.7E-34 T 14-10-2018 D521_2053 311cdf154ddd565678f73a73cf1578dc 201 Pfam PF13302 Acetyltransferase (GNAT) domain 16 152 1.5E-12 T 14-10-2018 IPR000182 GNAT domain D521_1938 311cac52f5371a63242323c72fa96119 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 177 198 1.2E-39 T 14-10-2018 D521_1938 311cac52f5371a63242323c72fa96119 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 201 221 1.2E-39 T 14-10-2018 D521_1938 311cac52f5371a63242323c72fa96119 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 105 125 1.2E-39 T 14-10-2018 D521_1938 311cac52f5371a63242323c72fa96119 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 127 146 1.2E-39 T 14-10-2018 D521_1938 311cac52f5371a63242323c72fa96119 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 221 238 1.2E-39 T 14-10-2018 D521_1938 311cac52f5371a63242323c72fa96119 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 239 256 1.2E-39 T 14-10-2018 D521_1938 311cac52f5371a63242323c72fa96119 385 PRINTS PR01166 Cytochrome c oxidase subunit II signature 93 105 1.2E-39 T 14-10-2018 D521_1938 311cac52f5371a63242323c72fa96119 385 Gene3D G3DSA:1.10.287.90 32 127 3.3E-26 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1938 311cac52f5371a63242323c72fa96119 385 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 202 250 - T 14-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1938 311cac52f5371a63242323c72fa96119 385 SUPERFAMILY SSF81464 32 125 3.43E-27 T 14-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1938 311cac52f5371a63242323c72fa96119 385 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 131 257 3.1E-38 T 14-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1938 311cac52f5371a63242323c72fa96119 385 SUPERFAMILY SSF46626 236 370 2.68E-26 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1938 311cac52f5371a63242323c72fa96119 385 SUPERFAMILY SSF49503 128 271 2.71E-52 T 14-10-2018 IPR008972 Cupredoxin D521_1938 311cac52f5371a63242323c72fa96119 385 Gene3D G3DSA:1.10.760.10 272 385 1.7E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1938 311cac52f5371a63242323c72fa96119 385 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 44 266 1.7E-58 T 14-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1938 311cac52f5371a63242323c72fa96119 385 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 35 116 8.0E-17 T 14-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1938 311cac52f5371a63242323c72fa96119 385 Gene3D G3DSA:2.60.40.420 128 270 4.2E-52 T 14-10-2018 IPR008972 Cupredoxin D521_1938 311cac52f5371a63242323c72fa96119 385 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 290 360 8.5E-15 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1354 1724b4c2d9cfbb1e9652436639090278 399 Pfam PF00155 Aminotransferase class I and II 29 394 2.5E-82 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 D521_1354 1724b4c2d9cfbb1e9652436639090278 399 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 245 258 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 D521_1354 1724b4c2d9cfbb1e9652436639090278 399 PRINTS PR00799 Aspartate aminotransferase signature 275 300 1.6E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 D521_1354 1724b4c2d9cfbb1e9652436639090278 399 PRINTS PR00799 Aspartate aminotransferase signature 208 220 1.6E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 D521_1354 1724b4c2d9cfbb1e9652436639090278 399 PRINTS PR00799 Aspartate aminotransferase signature 343 361 1.6E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 D521_1354 1724b4c2d9cfbb1e9652436639090278 399 PRINTS PR00799 Aspartate aminotransferase signature 177 196 1.6E-39 T 14-10-2018 IPR000796 Aspartate/other aminotransferase GO:0006520|GO:0008483 KEGG: 00220+2.6.1.1|KEGG: 00250+2.6.1.1|KEGG: 00270+2.6.1.1|KEGG: 00330+2.6.1.1|KEGG: 00350+2.6.1.1|KEGG: 00360+2.6.1.1|KEGG: 00400+2.6.1.1|KEGG: 00401+2.6.1.1|KEGG: 00710+2.6.1.1|KEGG: 00950+2.6.1.1|KEGG: 00960+2.6.1.1|MetaCyc: PWY-5913|MetaCyc: PWY-6318|MetaCyc: PWY-6638|MetaCyc: PWY-6642|MetaCyc: PWY-6643|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7383 D521_1354 1724b4c2d9cfbb1e9652436639090278 399 SUPERFAMILY SSF53383 2 398 5.67E-116 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_1354 1724b4c2d9cfbb1e9652436639090278 399 Gene3D G3DSA:3.40.640.10 62 302 2.9E-163 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_1354 1724b4c2d9cfbb1e9652436639090278 399 Gene3D G3DSA:3.90.1150.10 7 394 2.9E-163 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_0143 6259179cd0c944010d444247dc190f29 364 Pfam PF06071 Protein of unknown function (DUF933) 280 363 5.3E-39 T 14-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 D521_0143 6259179cd0c944010d444247dc190f29 364 Gene3D G3DSA:3.40.50.300 3 279 2.0E-152 T 14-10-2018 D521_0143 6259179cd0c944010d444247dc190f29 364 Gene3D G3DSA:1.10.150.300 113 201 2.0E-152 T 14-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 D521_0143 6259179cd0c944010d444247dc190f29 364 SUPERFAMILY SSF52540 3 302 8.2E-85 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0143 6259179cd0c944010d444247dc190f29 364 Gene3D G3DSA:3.10.20.30 48 362 2.0E-152 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_0143 6259179cd0c944010d444247dc190f29 364 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 364 2.8E-157 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 D521_0143 6259179cd0c944010d444247dc190f29 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.4E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0143 6259179cd0c944010d444247dc190f29 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 4.4E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0143 6259179cd0c944010d444247dc190f29 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 4.4E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0143 6259179cd0c944010d444247dc190f29 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 4.4E-34 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0143 6259179cd0c944010d444247dc190f29 364 Pfam PF01926 50S ribosome-binding GTPase 5 122 1.1E-22 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0143 6259179cd0c944010d444247dc190f29 364 SUPERFAMILY SSF81271 280 360 2.4E-35 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 D521_0143 6259179cd0c944010d444247dc190f29 364 PIRSF PIRSF006641 1 364 3.3E-155 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 D521_0143 6259179cd0c944010d444247dc190f29 364 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 364 44.669 T 14-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 D521_1008 b27fcdc93872e5017e083edb57fa1902 89 Gene3D G3DSA:1.10.150.250 1 88 7.9E-17 T 14-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily D521_1008 b27fcdc93872e5017e083edb57fa1902 89 Pfam PF03937 Flavinator of succinate dehydrogenase 9 72 3.2E-20 T 14-10-2018 IPR005631 Flavinator of succinate dehydrogenase D521_1008 b27fcdc93872e5017e083edb57fa1902 89 SUPERFAMILY SSF109910 6 65 3.53E-15 T 14-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily D521_0108 24bab880daad1573092884a4cd35fa61 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 195 42.691 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 D521_0108 24bab880daad1573092884a4cd35fa61 195 SUPERFAMILY SSF54211 1 85 3.04E-33 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0108 24bab880daad1573092884a4cd35fa61 195 SUPERFAMILY SSF54211 88 178 1.21E-34 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0108 24bab880daad1573092884a4cd35fa61 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 156 168 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 D521_0108 24bab880daad1573092884a4cd35fa61 195 Gene3D G3DSA:3.30.230.40 1 89 5.3E-37 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 D521_0108 24bab880daad1573092884a4cd35fa61 195 Gene3D G3DSA:3.30.230.40 90 195 1.8E-39 T 14-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 D521_0108 24bab880daad1573092884a4cd35fa61 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 174 1.1E-62 T 14-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 D521_0108 24bab880daad1573092884a4cd35fa61 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 14-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 D521_0743 34a142b688cd38d5d5bab47f75bb5c30 332 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 96 7.8E-6 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 D521_0743 34a142b688cd38d5d5bab47f75bb5c30 332 Gene3D G3DSA:3.90.180.10 25 330 4.1E-97 T 14-10-2018 D521_0743 34a142b688cd38d5d5bab47f75bb5c30 332 SMART SM00829 10 330 3.4E-37 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 D521_0743 34a142b688cd38d5d5bab47f75bb5c30 332 SUPERFAMILY SSF50129 1 145 1.25E-30 T 14-10-2018 IPR011032 GroES-like superfamily D521_0743 34a142b688cd38d5d5bab47f75bb5c30 332 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 332 6.8E-141 T 14-10-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 D521_0743 34a142b688cd38d5d5bab47f75bb5c30 332 Gene3D G3DSA:3.40.50.720 127 269 4.1E-97 T 14-10-2018 D521_0743 34a142b688cd38d5d5bab47f75bb5c30 332 Pfam PF00107 Zinc-binding dehydrogenase 158 273 3.1E-30 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 D521_0743 34a142b688cd38d5d5bab47f75bb5c30 332 SUPERFAMILY SSF51735 119 293 1.54E-51 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1108 73c6bc28e290a031b9bc81337cd2090b 1160 Gene3D G3DSA:3.40.50.300 336 479 4.4E-30 T 14-10-2018 D521_1108 73c6bc28e290a031b9bc81337cd2090b 1160 Gene3D G3DSA:3.40.50.300 787 929 2.0E-19 T 14-10-2018 D521_1108 73c6bc28e290a031b9bc81337cd2090b 1160 SUPERFAMILY SSF52540 1 920 1.1E-94 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1108 73c6bc28e290a031b9bc81337cd2090b 1160 Pfam PF00580 UvrD/REP helicase N-terminal domain 2 444 3.6E-46 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 D521_1108 73c6bc28e290a031b9bc81337cd2090b 1160 Pfam PF13361 UvrD-like helicase C-terminal domain 585 911 3.7E-21 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 D521_1108 73c6bc28e290a031b9bc81337cd2090b 1160 Gene3D G3DSA:1.10.486.10 621 786 5.0E-23 T 14-10-2018 D521_1108 73c6bc28e290a031b9bc81337cd2090b 1160 SUPERFAMILY SSF52980 1010 1140 2.57E-5 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 D521_1177 7d8baf736bbda856b9fb43fd631f4a8c 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_1177 7d8baf736bbda856b9fb43fd631f4a8c 234 SUPERFAMILY SSF52540 2 230 2.72E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1177 7d8baf736bbda856b9fb43fd631f4a8c 234 SMART SM00382 26 226 1.8E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1177 7d8baf736bbda856b9fb43fd631f4a8c 234 Gene3D G3DSA:3.40.50.300 1 234 1.1E-63 T 14-10-2018 D521_1177 7d8baf736bbda856b9fb43fd631f4a8c 234 Pfam PF00005 ABC transporter 17 162 1.5E-32 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0422 cb91056f78c06bf6aaf4c471e19d8e4b 201 Gene3D G3DSA:3.40.50.12740 1 200 4.4E-54 T 14-10-2018 D521_0422 cb91056f78c06bf6aaf4c471e19d8e4b 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 9.3E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0422 cb91056f78c06bf6aaf4c471e19d8e4b 201 SUPERFAMILY SSF52172 7 171 2.43E-23 T 14-10-2018 IPR011006 CheY-like superfamily D521_0422 cb91056f78c06bf6aaf4c471e19d8e4b 201 SMART SM00421 137 194 2.7E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0422 cb91056f78c06bf6aaf4c471e19d8e4b 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0422 cb91056f78c06bf6aaf4c471e19d8e4b 201 Pfam PF00072 Response regulator receiver domain 7 96 6.1E-18 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_0422 cb91056f78c06bf6aaf4c471e19d8e4b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 2.8E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0422 cb91056f78c06bf6aaf4c471e19d8e4b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 2.8E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0422 cb91056f78c06bf6aaf4c471e19d8e4b 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 2.8E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0422 cb91056f78c06bf6aaf4c471e19d8e4b 201 SMART SM00448 1 99 1.0E-9 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1964 6e4944473bee05aa2fd2ef73f4208c47 364 Pfam PF04892 VanZ like family 64 140 9.1E-11 T 14-10-2018 IPR006976 VanZ-like D521_0968 59083cf6708055ec07c5e2774eba5c0c 527 SUPERFAMILY SSF52540 288 521 5.5E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0968 59083cf6708055ec07c5e2774eba5c0c 527 SUPERFAMILY SSF52540 3 229 1.73E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0968 59083cf6708055ec07c5e2774eba5c0c 527 Pfam PF00005 ABC transporter 327 462 5.8E-18 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0968 59083cf6708055ec07c5e2774eba5c0c 527 Pfam PF00005 ABC transporter 10 176 3.8E-19 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0968 59083cf6708055ec07c5e2774eba5c0c 527 Gene3D G3DSA:3.40.50.300 2 285 4.5E-58 T 14-10-2018 D521_0968 59083cf6708055ec07c5e2774eba5c0c 527 Gene3D G3DSA:3.40.50.300 301 526 5.9E-44 T 14-10-2018 D521_0968 59083cf6708055ec07c5e2774eba5c0c 527 Pfam PF12848 ABC transporter 216 301 2.3E-22 T 14-10-2018 IPR032781 ABC-transporter extension domain D521_0968 59083cf6708055ec07c5e2774eba5c0c 527 SMART SM00382 335 506 9.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0968 59083cf6708055ec07c5e2774eba5c0c 527 SMART SM00382 18 230 1.7E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1702 619d1ba4c9eed2b598f973d9bddda31b 325 Gene3D G3DSA:3.90.1200.10 111 325 7.6E-71 T 14-10-2018 D521_1702 619d1ba4c9eed2b598f973d9bddda31b 325 Pfam PF01636 Phosphotransferase enzyme family 28 266 2.0E-28 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase D521_1702 619d1ba4c9eed2b598f973d9bddda31b 325 Gene3D G3DSA:3.30.200.20 1 107 5.2E-32 T 14-10-2018 D521_1702 619d1ba4c9eed2b598f973d9bddda31b 325 SUPERFAMILY SSF56112 5 322 4.81E-70 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily D521_1702 619d1ba4c9eed2b598f973d9bddda31b 325 TIGRFAM TIGR00938 thrB_alt: homoserine kinase 1 320 5.2E-97 T 14-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 D521_1702 619d1ba4c9eed2b598f973d9bddda31b 325 Hamap MF_00301 Homoserine kinase [thrB]. 1 325 147.763 T 14-10-2018 IPR005280 Homoserine kinase, type II GO:0004413|GO:0009088 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 D521_0322 044c0855bde2867d0a613e4eafc16845 337 Gene3D G3DSA:3.30.360.10 124 287 2.9E-29 T 14-10-2018 D521_0322 044c0855bde2867d0a613e4eafc16845 337 SUPERFAMILY SSF55347 127 273 1.08E-10 T 14-10-2018 D521_0322 044c0855bde2867d0a613e4eafc16845 337 Gene3D G3DSA:3.40.50.720 3 310 2.9E-29 T 14-10-2018 D521_0322 044c0855bde2867d0a613e4eafc16845 337 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 106 7.7E-8 T 14-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 D521_0322 044c0855bde2867d0a613e4eafc16845 337 SUPERFAMILY SSF51735 1 156 4.23E-14 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1508 bf17e82b1cf555d5c833bf58d0bde73c 149 SUPERFAMILY SSF47175 25 149 5.59E-40 T 14-10-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 D521_1508 bf17e82b1cf555d5c833bf58d0bde73c 149 Pfam PF01322 Cytochrome C' 30 147 3.2E-38 T 14-10-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 D521_1508 bf17e82b1cf555d5c833bf58d0bde73c 149 PIRSF PIRSF000027 5 149 1.8E-44 T 14-10-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 D521_1508 bf17e82b1cf555d5c833bf58d0bde73c 149 PRINTS PR00608 Class II cytochrome C signature 136 147 8.6E-8 T 14-10-2018 IPR015984 Cytochrome c prime, subgroup D521_1508 bf17e82b1cf555d5c833bf58d0bde73c 149 PRINTS PR00608 Class II cytochrome C signature 113 136 8.6E-8 T 14-10-2018 IPR015984 Cytochrome c prime, subgroup D521_1508 bf17e82b1cf555d5c833bf58d0bde73c 149 Gene3D G3DSA:1.20.120.10 24 149 6.4E-45 T 14-10-2018 D521_1684 e98401ff4577160cdff574a82be7f199 556 SUPERFAMILY SSF103473 20 552 4.97E-58 T 14-10-2018 IPR036259 MFS transporter superfamily D521_1684 e98401ff4577160cdff574a82be7f199 556 Gene3D G3DSA:1.20.1250.20 440 555 2.1E-9 T 14-10-2018 D521_1684 e98401ff4577160cdff574a82be7f199 556 Gene3D G3DSA:1.20.1250.20 20 358 8.6E-54 T 14-10-2018 D521_1684 e98401ff4577160cdff574a82be7f199 556 ProSitePatterns PS00217 Sugar transport proteins signature 2. 133 158 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 D521_1684 e98401ff4577160cdff574a82be7f199 556 Pfam PF00083 Sugar (and other) transporter 24 238 2.0E-27 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 D521_1684 e98401ff4577160cdff574a82be7f199 556 Pfam PF00083 Sugar (and other) transporter 456 554 2.2E-5 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 D521_1774 c36cd0c513179765660960a3993d31ed 324 Gene3D G3DSA:1.20.1640.10 107 307 6.6E-10 T 14-10-2018 D521_1774 c36cd0c513179765660960a3993d31ed 324 Pfam PF02355 Protein export membrane protein 114 296 3.9E-62 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial D521_1774 c36cd0c513179765660960a3993d31ed 324 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 38 288 5.1E-73 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 D521_1774 c36cd0c513179765660960a3993d31ed 324 PRINTS PR01755 Bacterial translocase SecF protein signature 37 52 1.2E-26 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial D521_1774 c36cd0c513179765660960a3993d31ed 324 PRINTS PR01755 Bacterial translocase SecF protein signature 156 170 1.2E-26 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial D521_1774 c36cd0c513179765660960a3993d31ed 324 PRINTS PR01755 Bacterial translocase SecF protein signature 204 222 1.2E-26 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial D521_1774 c36cd0c513179765660960a3993d31ed 324 PRINTS PR01755 Bacterial translocase SecF protein signature 236 251 1.2E-26 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial D521_1774 c36cd0c513179765660960a3993d31ed 324 SUPERFAMILY SSF82866 71 296 4.97E-40 T 14-10-2018 D521_1774 c36cd0c513179765660960a3993d31ed 324 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 10 299 28.498 T 14-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 D521_1774 c36cd0c513179765660960a3993d31ed 324 Pfam PF07549 SecD/SecF GG Motif 32 55 1.9E-6 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site D521_1774 c36cd0c513179765660960a3993d31ed 324 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 103 285 1.4E-47 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial D521_1100 91ebd21a5c6bac8803ce7a58958ac51b 218 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 179 205 1.2E-5 T 14-10-2018 IPR024530 Putative quorum-sensing-regulated virulence factor D521_1100 91ebd21a5c6bac8803ce7a58958ac51b 218 SMART SM00479 3 162 2.4E-4 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III D521_1100 91ebd21a5c6bac8803ce7a58958ac51b 218 SUPERFAMILY SSF53098 3 188 3.92E-28 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1100 91ebd21a5c6bac8803ce7a58958ac51b 218 Gene3D G3DSA:3.30.420.10 4 175 2.0E-22 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_0803 14e6d863e7ce65945e43c0121a866d45 494 PIRSF PIRSF001267 1 494 4.2E-175 T 14-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 D521_0803 14e6d863e7ce65945e43c0121a866d45 494 Gene3D G3DSA:3.30.420.40 2 299 9.1E-73 T 14-10-2018 D521_0803 14e6d863e7ce65945e43c0121a866d45 494 Gene3D G3DSA:1.10.3210.10 306 493 6.0E-53 T 14-10-2018 D521_0803 14e6d863e7ce65945e43c0121a866d45 494 Pfam PF02541 Ppx/GppA phosphatase family 13 303 3.4E-69 T 14-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 D521_0803 14e6d863e7ce65945e43c0121a866d45 494 Gene3D G3DSA:3.30.420.150 97 291 9.1E-73 T 14-10-2018 D521_0803 14e6d863e7ce65945e43c0121a866d45 494 SUPERFAMILY SSF53067 118 306 1.11E-41 T 14-10-2018 D521_0803 14e6d863e7ce65945e43c0121a866d45 494 SUPERFAMILY SSF53067 7 113 8.42E-24 T 14-10-2018 D521_0803 14e6d863e7ce65945e43c0121a866d45 494 SUPERFAMILY SSF109604 309 491 7.38E-42 T 14-10-2018 D521_1090 99a3d2a92b5be4bab7ca4cc5903e3aca 88 Gene3D G3DSA:1.10.1220.10 4 53 1.1E-13 T 14-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 D521_1090 99a3d2a92b5be4bab7ca4cc5903e3aca 88 Pfam PF04221 RelB antitoxin 7 76 8.2E-22 T 14-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ D521_1090 99a3d2a92b5be4bab7ca4cc5903e3aca 88 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 6 84 1.2E-20 T 14-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ D521_1090 99a3d2a92b5be4bab7ca4cc5903e3aca 88 PIRSF PIRSF003108 1 88 3.1E-30 T 14-10-2018 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 D521_1399 cca3dd3ac542ce3d336b365d6a118c30 150 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 6.5E-43 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1399 cca3dd3ac542ce3d336b365d6a118c30 150 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 4.8E-21 T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1399 cca3dd3ac542ce3d336b365d6a118c30 150 SUPERFAMILY SSF55658 1 56 9.77E-17 T 14-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal D521_1399 cca3dd3ac542ce3d336b365d6a118c30 150 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 9.0E-25 T 14-10-2018 IPR020069 Ribosomal protein L9, C-terminal D521_1399 cca3dd3ac542ce3d336b365d6a118c30 150 Gene3D G3DSA:3.40.5.10 1 50 2.6E-21 T 14-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1399 cca3dd3ac542ce3d336b365d6a118c30 150 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.138 T 14-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1399 cca3dd3ac542ce3d336b365d6a118c30 150 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 14-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1399 cca3dd3ac542ce3d336b365d6a118c30 150 SUPERFAMILY SSF55653 60 148 1.57E-24 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily D521_1399 cca3dd3ac542ce3d336b365d6a118c30 150 Gene3D G3DSA:3.10.430.100 61 148 1.2E-25 T 14-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily D521_1781 3cb5660ec954677e4a427b896deb1c33 455 PIRSF PIRSF000204 1 455 1.3E-205 T 14-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 D521_1781 3cb5660ec954677e4a427b896deb1c33 455 Gene3D G3DSA:3.40.50.1220 277 455 2.8E-82 T 14-10-2018 D521_1781 3cb5660ec954677e4a427b896deb1c33 455 Pfam PF02233 NAD(P) transhydrogenase beta subunit 7 452 1.6E-189 T 14-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 D521_1781 3cb5660ec954677e4a427b896deb1c33 455 SUPERFAMILY SSF52467 284 454 5.09E-72 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily D521_0970 a2732b984b35249dd97cea467c0a56be 392 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 D521_0970 a2732b984b35249dd97cea467c0a56be 392 SUPERFAMILY SSF56645 6 237 9.95E-77 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 D521_0970 a2732b984b35249dd97cea467c0a56be 392 Gene3D G3DSA:1.20.140.10 240 392 3.9E-42 T 14-10-2018 D521_0970 a2732b984b35249dd97cea467c0a56be 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 131 4.8E-35 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 D521_0970 a2732b984b35249dd97cea467c0a56be 392 Gene3D G3DSA:1.10.540.10 1 133 8.9E-44 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 D521_0970 a2732b984b35249dd97cea467c0a56be 392 Gene3D G3DSA:2.40.110.10 134 237 2.0E-36 T 14-10-2018 D521_0970 a2732b984b35249dd97cea467c0a56be 392 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 135 226 1.1E-18 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 D521_0970 a2732b984b35249dd97cea467c0a56be 392 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 239 384 5.5E-29 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 D521_0970 a2732b984b35249dd97cea467c0a56be 392 SUPERFAMILY SSF47203 241 389 3.22E-43 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 176 321 2.3E-26 T 14-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 21 326 40.255 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 Gene3D G3DSA:3.40.50.1370 156 303 1.3E-89 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 60 82 3.7E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 305 319 3.7E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 240 249 3.7E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 98 107 3.7E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 155 172 3.7E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 PRINTS PR00101 Aspartate carbamoyltransferase signature 281 286 3.7E-29 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 23 168 2.0E-39 T 14-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 Gene3D G3DSA:3.40.50.1370 27 319 1.3E-89 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 SUPERFAMILY SSF53671 22 325 1.31E-94 T 14-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 23 323 1.3E-91 T 14-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 289 312 1.8E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 156 167 1.8E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 277 286 1.8E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 70 89 1.8E-18 T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 D521_0249 bb15c694a030117baf8c3851eafc33cf 326 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 70 77 - T 14-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 D521_1906 1b0e16e053caedc71a274dcde948779e 185 Pfam PF03968 OstA-like protein 36 153 7.6E-14 T 14-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal D521_1906 1b0e16e053caedc71a274dcde948779e 185 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 24 164 1.0E-24 T 14-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 D521_1906 1b0e16e053caedc71a274dcde948779e 185 Gene3D G3DSA:2.60.450.10 26 182 3.4E-26 T 14-10-2018 D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 SUPERFAMILY SSF48173 211 488 1.96E-101 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 Gene3D G3DSA:3.40.50.620 5 215 1.5E-69 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 Gene3D G3DSA:1.25.40.80 138 295 1.5E-69 T 14-10-2018 D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 ProSitePatterns PS00691 DNA photolyases class 1 signature 2. 354 373 - T 14-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 Gene3D G3DSA:1.10.579.10 302 490 6.3E-77 T 14-10-2018 D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 Pfam PF03441 FAD binding domain of DNA photolyase 281 483 2.6E-84 T 14-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 PRINTS PR00147 DNA photolyase signature 393 407 3.6E-27 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 PRINTS PR00147 DNA photolyase signature 149 165 3.6E-27 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 PRINTS PR00147 DNA photolyase signature 354 372 3.6E-27 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 PRINTS PR00147 DNA photolyase signature 334 350 3.6E-27 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 Pfam PF00875 DNA photolyase 4 171 1.2E-48 T 14-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 D521_0244 d883c5ce499d8af7fa2ac94bd3ccf856 496 SUPERFAMILY SSF52425 4 188 4.58E-51 T 14-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 D521_1927 b80c35f26098a622b98a8c972c2befe5 201 Pfam PF02630 SCO1/SenC 16 179 1.7E-34 T 14-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1927 b80c35f26098a622b98a8c972c2befe5 201 Gene3D G3DSA:3.40.30.10 27 201 1.2E-51 T 14-10-2018 D521_1927 b80c35f26098a622b98a8c972c2befe5 201 SUPERFAMILY SSF52833 43 201 1.63E-48 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0972 f26f2148779ada78a5df1ad6dca9a413 114 SUPERFAMILY SSF52799 16 104 3.28E-5 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like D521_0972 f26f2148779ada78a5df1ad6dca9a413 114 Pfam PF04273 Putative phosphatase (DUF442) 10 110 2.3E-31 T 14-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 D521_0972 f26f2148779ada78a5df1ad6dca9a413 114 TIGRFAM TIGR01244 TIGR01244: TIGR01244 family protein 16 109 2.3E-27 T 14-10-2018 IPR005939 Beta-lactamase hydrolase-like GO:0016787 D521_0972 f26f2148779ada78a5df1ad6dca9a413 114 Gene3D G3DSA:3.90.190.10 5 114 1.4E-30 T 14-10-2018 IPR029021 Protein-tyrosine phosphatase-like D521_0782 2246d005d76535ecec1ac417a5d07d57 208 SUPERFAMILY SSF75471 5 95 1.83E-24 T 14-10-2018 IPR035920 YhbY-like superfamily D521_0782 2246d005d76535ecec1ac417a5d07d57 208 SMART SM01103 6 89 3.3E-38 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 D521_0782 2246d005d76535ecec1ac417a5d07d57 208 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 14 92 3.0E-26 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 D521_0782 2246d005d76535ecec1ac417a5d07d57 208 Gene3D G3DSA:3.30.110.60 4 99 3.5E-25 T 14-10-2018 IPR035920 YhbY-like superfamily D521_0782 2246d005d76535ecec1ac417a5d07d57 208 Pfam PF01985 CRS1 / YhbY (CRM) domain 7 89 1.6E-15 T 14-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 D521_1086 a08a27d555f507f6775b91ed1f164998 423 SUPERFAMILY SSF111369 134 349 1.44E-14 T 14-10-2018 D521_1086 a08a27d555f507f6775b91ed1f164998 423 Gene3D G3DSA:2.40.420.20 113 403 3.7E-53 T 14-10-2018 D521_1086 a08a27d555f507f6775b91ed1f164998 423 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 123 342 1.2E-59 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain D521_1086 a08a27d555f507f6775b91ed1f164998 423 Gene3D G3DSA:2.40.30.170 123 348 3.7E-53 T 14-10-2018 D521_1086 a08a27d555f507f6775b91ed1f164998 423 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 114 416 1.2E-35 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 D521_1086 a08a27d555f507f6775b91ed1f164998 423 Gene3D G3DSA:2.40.50.100 137 268 3.7E-53 T 14-10-2018 D521_1086 a08a27d555f507f6775b91ed1f164998 423 Gene3D G3DSA:1.10.287.470 171 234 3.7E-53 T 14-10-2018 D521_0172 ab5aae0207a347b256886a3cd6028515 337 Gene3D G3DSA:3.30.1490.20 136 201 3.5E-68 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 D521_0172 ab5aae0207a347b256886a3cd6028515 337 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 28 329 34.241 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0172 ab5aae0207a347b256886a3cd6028515 337 Pfam PF01820 D-ala D-ala ligase N-terminus 29 111 2.2E-17 T 14-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0172 ab5aae0207a347b256886a3cd6028515 337 SUPERFAMILY SSF56059 121 325 1.54E-51 T 14-10-2018 D521_0172 ab5aae0207a347b256886a3cd6028515 337 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 29 328 7.6E-96 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0172 ab5aae0207a347b256886a3cd6028515 337 PIRSF PIRSF039102 67 334 2.0E-83 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0172 ab5aae0207a347b256886a3cd6028515 337 PIRSF PIRSF039102 25 69 5.7E-7 T 14-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0172 ab5aae0207a347b256886a3cd6028515 337 SUPERFAMILY SSF52440 29 121 7.39E-29 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily D521_0172 ab5aae0207a347b256886a3cd6028515 337 Gene3D G3DSA:3.40.50.20 16 109 4.8E-29 T 14-10-2018 D521_0172 ab5aae0207a347b256886a3cd6028515 337 Pfam PF07478 D-ala D-ala ligase C-terminus 135 325 7.9E-56 T 14-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0172 ab5aae0207a347b256886a3cd6028515 337 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 88 99 - T 14-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0172 ab5aae0207a347b256886a3cd6028515 337 Gene3D G3DSA:3.30.470.20 110 323 3.5E-68 T 14-10-2018 D521_0875 4ef04a3079e766dee32dcf2ce6c45eea 172 Gene3D G3DSA:3.40.50.2020 2 171 2.6E-49 T 14-10-2018 D521_0875 4ef04a3079e766dee32dcf2ce6c45eea 172 Pfam PF00156 Phosphoribosyl transferase domain 47 148 6.3E-16 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 D521_0875 4ef04a3079e766dee32dcf2ce6c45eea 172 SUPERFAMILY SSF53271 3 168 6.69E-42 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like D521_0875 4ef04a3079e766dee32dcf2ce6c45eea 172 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 172 29.505 T 14-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 D521_0006 da6d3943627828f4fddea029b94d20c4 255 Gene3D G3DSA:3.40.50.300 3 249 4.7E-56 T 14-10-2018 D521_0006 da6d3943627828f4fddea029b94d20c4 255 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 227 248 9.4E-8 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal D521_0006 da6d3943627828f4fddea029b94d20c4 255 SUPERFAMILY SSF52540 7 248 2.44E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0006 da6d3943627828f4fddea029b94d20c4 255 SMART SM00382 32 226 8.6E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0006 da6d3943627828f4fddea029b94d20c4 255 Pfam PF00005 ABC transporter 24 179 1.6E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0587 2bb33536a626670a6c0fb007f2be1f5f 468 Pfam PF16868 NMT1-like family 61 244 2.9E-13 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family D521_0587 2bb33536a626670a6c0fb007f2be1f5f 468 Gene3D G3DSA:3.40.190.10 61 304 5.0E-23 T 14-10-2018 D521_0587 2bb33536a626670a6c0fb007f2be1f5f 468 SUPERFAMILY SSF53850 55 307 6.73E-28 T 14-10-2018 D521_0587 2bb33536a626670a6c0fb007f2be1f5f 468 Gene3D G3DSA:3.40.190.10 135 281 5.0E-23 T 14-10-2018 D521_0003 9ca45a67816401d6db412ad36bca545b 832 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 11 832 4.0E-285 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 8 832 95.979 T 14-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 Gene3D G3DSA:3.30.565.10 8 241 1.8E-85 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0003 9ca45a67816401d6db412ad36bca545b 832 SUPERFAMILY SSF56719 420 822 7.85E-86 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 D521_0003 9ca45a67816401d6db412ad36bca545b 832 SUPERFAMILY SSF54211 242 418 4.36E-55 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0003 9ca45a67816401d6db412ad36bca545b 832 SMART SM00387 37 197 3.8E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_0003 9ca45a67816401d6db412ad36bca545b 832 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 764 821 9.8E-28 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR00418 DNA topoisomerase II family signature 123 137 7.1E-68 T 14-10-2018 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR00418 DNA topoisomerase II family signature 764 780 7.1E-68 T 14-10-2018 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR00418 DNA topoisomerase II family signature 551 563 7.1E-68 T 14-10-2018 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR00418 DNA topoisomerase II family signature 531 548 7.1E-68 T 14-10-2018 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR00418 DNA topoisomerase II family signature 41 56 7.1E-68 T 14-10-2018 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR00418 DNA topoisomerase II family signature 446 460 7.1E-68 T 14-10-2018 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR00418 DNA topoisomerase II family signature 513 529 7.1E-68 T 14-10-2018 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR00418 DNA topoisomerase II family signature 76 89 7.1E-68 T 14-10-2018 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR00418 DNA topoisomerase II family signature 294 307 7.1E-68 T 14-10-2018 D521_0003 9ca45a67816401d6db412ad36bca545b 832 Pfam PF00204 DNA gyrase B 242 416 4.3E-55 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0003 9ca45a67816401d6db412ad36bca545b 832 SMART SM00433 41 825 5.8E-241 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0003 9ca45a67816401d6db412ad36bca545b 832 Pfam PF01751 Toprim domain 445 557 3.5E-19 T 14-10-2018 IPR006171 TOPRIM domain D521_0003 9ca45a67816401d6db412ad36bca545b 832 Gene3D G3DSA:3.40.50.670 710 830 1.1E-24 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0003 9ca45a67816401d6db412ad36bca545b 832 Gene3D G3DSA:3.30.230.10 242 418 1.2E-68 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup D521_0003 9ca45a67816401d6db412ad36bca545b 832 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 38 161 4.4E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 338 354 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 268 286 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 386 400 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 400 420 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 217 230 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 785 797 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 801 817 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 202 217 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 241 263 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 496 505 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 PRINTS PR01159 DNA gyrase subunit B signature 11 21 5.7E-75 T 14-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0003 9ca45a67816401d6db412ad36bca545b 832 ProSitePatterns PS00177 DNA topoisomerase II signature. 448 456 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0003 9ca45a67816401d6db412ad36bca545b 832 SUPERFAMILY SSF55874 10 237 1.67E-62 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0003 9ca45a67816401d6db412ad36bca545b 832 Gene3D G3DSA:3.40.50.670 424 611 1.9E-75 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0987 c9bf2875e1e25b775737252e4aa9ac72 216 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 7 201 7.1E-60 T 14-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 D521_0987 c9bf2875e1e25b775737252e4aa9ac72 216 SUPERFAMILY SSF161098 4 202 2.88E-42 T 14-10-2018 IPR035906 MetI-like superfamily D521_0987 c9bf2875e1e25b775737252e4aa9ac72 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 21 200 2.1E-17 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 D521_0987 c9bf2875e1e25b775737252e4aa9ac72 216 Gene3D G3DSA:1.10.3720.10 2 204 9.8E-48 T 14-10-2018 IPR035906 MetI-like superfamily D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 SUPERFAMILY SSF69304 160 432 1.03E-58 T 14-10-2018 D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 Pfam PF04052 TolB amino-terminal domain 33 132 6.1E-26 T 14-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 Gene3D G3DSA:2.120.10.30 169 435 2.4E-84 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 Gene3D G3DSA:3.40.50.10070 29 168 2.7E-35 T 14-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 25 431 2.2E-144 T 14-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 Pfam PF07676 WD40-like Beta Propeller Repeat 198 229 3.2E-8 T 14-10-2018 IPR011659 WD40-like Beta Propeller D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 Pfam PF07676 WD40-like Beta Propeller Repeat 282 317 1.8E-10 T 14-10-2018 IPR011659 WD40-like Beta Propeller D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 Pfam PF07676 WD40-like Beta Propeller Repeat 329 364 2.2E-6 T 14-10-2018 IPR011659 WD40-like Beta Propeller D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 Pfam PF07676 WD40-like Beta Propeller Repeat 240 272 3.5E-9 T 14-10-2018 IPR011659 WD40-like Beta Propeller D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 SUPERFAMILY SSF52964 39 165 3.53E-30 T 14-10-2018 D521_0277 88a0f486aa83a758cf8c7dc7ce0b382d 435 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 15 430 44.905 T 14-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Gene3D G3DSA:3.40.50.11180 27 341 7.9E-107 T 14-10-2018 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Gene3D G3DSA:3.30.2060.10 135 220 7.9E-107 T 14-10-2018 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Gene3D G3DSA:3.40.50.300 497 1013 4.8E-224 T 14-10-2018 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 152 1105 0.0 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 SUPERFAMILY SSF52540 807 1013 3.08E-45 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 SUPERFAMILY SSF52540 361 482 4.78E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Gene3D G3DSA:3.40.50.300 566 805 4.8E-224 T 14-10-2018 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 SUPERFAMILY SSF52540 16 346 2.72E-90 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 SMART SM00490 850 934 5.8E-16 T 14-10-2018 IPR001650 Helicase, C-terminal D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Pfam PF03461 TRCF domain 1033 1126 5.0E-24 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Pfam PF00271 Helicase conserved C-terminal domain 830 933 4.6E-16 T 14-10-2018 IPR001650 Helicase, C-terminal D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 SUPERFAMILY SSF52540 547 807 1.21E-58 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 SMART SM00982 1032 1132 9.7E-45 T 14-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 SMART SM01058 498 600 2.1E-40 T 14-10-2018 IPR003711 CarD-like/TRCF domain D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 SUPERFAMILY SSF143517 1018 1169 1.7E-37 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Gene3D G3DSA:2.30.30.840 502 565 4.8E-224 T 14-10-2018 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 42 1133 26.73 T 14-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Gene3D G3DSA:3.90.1150.50 1028 1178 1.3E-39 T 14-10-2018 IPR037235 TRCF-like, C-terminal domain D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Pfam PF00270 DEAD/DEAH box helicase 629 786 1.6E-16 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 SUPERFAMILY SSF141259 490 572 2.48E-19 T 14-10-2018 IPR036101 CarD-like/TRCF domain superfamily D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 SMART SM00487 624 814 3.3E-32 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_0926 741f6b402565a44a6d858a8d3f8f3edb 1184 Pfam PF02559 CarD-like/TRCF domain 499 599 1.8E-23 T 14-10-2018 IPR003711 CarD-like/TRCF domain D521_1416 d6c33000299b30beee363bdaf5853a4c 130 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 129 23.526 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 D521_1416 d6c33000299b30beee363bdaf5853a4c 130 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 128 3.0E-21 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 D521_1416 d6c33000299b30beee363bdaf5853a4c 130 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 128 1.3E-26 T 14-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 D521_1416 d6c33000299b30beee363bdaf5853a4c 130 Gene3D G3DSA:3.90.470.20 1 128 6.4E-30 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 D521_1416 d6c33000299b30beee363bdaf5853a4c 130 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 113 2.2E-16 T 14-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 D521_1416 d6c33000299b30beee363bdaf5853a4c 130 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 95 2.0E-30 T 14-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 D521_1416 d6c33000299b30beee363bdaf5853a4c 130 SUPERFAMILY SSF56214 1 126 3.66E-24 T 14-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 D521_1773 3b65655e94b8451c7c860aaa94c9bb41 619 Gene3D G3DSA:1.20.1640.10 423 607 1.0E-11 T 14-10-2018 D521_1773 3b65655e94b8451c7c860aaa94c9bb41 619 Gene3D G3DSA:3.30.70.3400 220 296 3.3E-17 T 14-10-2018 D521_1773 3b65655e94b8451c7c860aaa94c9bb41 619 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 2 610 45.803 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 D521_1773 3b65655e94b8451c7c860aaa94c9bb41 619 Pfam PF13721 SecD export protein N-terminal TM region 1 112 1.5E-33 T 14-10-2018 IPR027398 SecD export protein N-terminal TM domain D521_1773 3b65655e94b8451c7c860aaa94c9bb41 619 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 132 595 3.9E-129 T 14-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 D521_1773 3b65655e94b8451c7c860aaa94c9bb41 619 Pfam PF02355 Protein export membrane protein 428 598 8.4E-22 T 14-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial D521_1773 3b65655e94b8451c7c860aaa94c9bb41 619 Gene3D G3DSA:3.30.1360.200 315 422 1.4E-24 T 14-10-2018 D521_1773 3b65655e94b8451c7c860aaa94c9bb41 619 SUPERFAMILY SSF82866 344 602 2.22E-35 T 14-10-2018 D521_1773 3b65655e94b8451c7c860aaa94c9bb41 619 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 355 588 1.4E-69 T 14-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial D521_1773 3b65655e94b8451c7c860aaa94c9bb41 619 Pfam PF07549 SecD/SecF GG Motif 128 148 9.2E-5 T 14-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site D521_1765 0f82546e07fc6e7953f4f2ea12eca247 426 SUPERFAMILY SSF54862 19 107 4.18E-21 T 14-10-2018 D521_1765 0f82546e07fc6e7953f4f2ea12eca247 426 Gene3D G3DSA:1.10.1060.10 2 109 2.0E-11 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_1765 0f82546e07fc6e7953f4f2ea12eca247 426 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 75 86 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1765 0f82546e07fc6e7953f4f2ea12eca247 426 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 25 36 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1765 0f82546e07fc6e7953f4f2ea12eca247 426 PIRSF PIRSF000139 7 424 1.0E-112 T 14-10-2018 D521_1765 0f82546e07fc6e7953f4f2ea12eca247 426 Pfam PF12838 4Fe-4S dicluster domain 24 89 5.7E-13 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1765 0f82546e07fc6e7953f4f2ea12eca247 426 Pfam PF02754 Cysteine-rich domain 313 400 2.7E-9 T 14-10-2018 IPR004017 Cysteine-rich domain D521_1765 0f82546e07fc6e7953f4f2ea12eca247 426 Pfam PF02754 Cysteine-rich domain 181 263 2.4E-10 T 14-10-2018 IPR004017 Cysteine-rich domain D521_0583 075da031fab5d179d246788b2977b813 249 Gene3D G3DSA:3.40.1410.10 85 245 3.0E-23 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily D521_0583 075da031fab5d179d246788b2977b813 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 1.6E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0583 075da031fab5d179d246788b2977b813 249 SMART SM00345 16 75 2.7E-14 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0583 075da031fab5d179d246788b2977b813 249 SUPERFAMILY SSF46785 7 85 2.24E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0583 075da031fab5d179d246788b2977b813 249 SMART SM00866 96 238 5.0E-16 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 D521_0583 075da031fab5d179d246788b2977b813 249 Pfam PF07702 UTRA domain 115 237 1.0E-16 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 D521_0583 075da031fab5d179d246788b2977b813 249 Gene3D G3DSA:1.10.10.10 5 83 4.0E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0583 075da031fab5d179d246788b2977b813 249 SUPERFAMILY SSF64288 63 244 6.91E-27 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily D521_0583 075da031fab5d179d246788b2977b813 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 7.1E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0583 075da031fab5d179d246788b2977b813 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 7.1E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1095 ed666040121c5c8d70acb362d26f111f 102 Gene3D G3DSA:3.10.450.530 1 93 8.6E-15 T 14-10-2018 IPR038573 Ribonuclease toxin BrnT superfamily D521_1095 ed666040121c5c8d70acb362d26f111f 102 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 15 91 3.4E-19 T 14-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system D521_1926 b1396437576fbb078e52de3429e393d4 313 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 101 114 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1926 b1396437576fbb078e52de3429e393d4 313 Gene3D G3DSA:1.10.601.10 40 149 3.1E-29 T 14-10-2018 D521_1926 b1396437576fbb078e52de3429e393d4 313 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 72 307 9.9E-30 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 D521_1926 b1396437576fbb078e52de3429e393d4 313 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 23 310 50.525 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 D521_1926 b1396437576fbb078e52de3429e393d4 313 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 38 309 8.5E-116 T 14-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 D521_1926 b1396437576fbb078e52de3429e393d4 313 PRINTS PR00046 Major sigma-70 factor signature 278 293 5.3E-16 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1926 b1396437576fbb078e52de3429e393d4 313 PRINTS PR00046 Major sigma-70 factor signature 125 133 5.3E-16 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1926 b1396437576fbb078e52de3429e393d4 313 PRINTS PR00046 Major sigma-70 factor signature 293 304 5.3E-16 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1926 b1396437576fbb078e52de3429e393d4 313 PRINTS PR00046 Major sigma-70 factor signature 101 114 5.3E-16 T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_1926 b1396437576fbb078e52de3429e393d4 313 Gene3D G3DSA:1.10.10.10 245 312 1.4E-13 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1926 b1396437576fbb078e52de3429e393d4 313 SUPERFAMILY SSF88659 211 310 7.1E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like D521_1926 b1396437576fbb078e52de3429e393d4 313 Pfam PF04545 Sigma-70, region 4 250 305 6.0E-13 T 14-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 D521_1926 b1396437576fbb078e52de3429e393d4 313 Pfam PF04542 Sigma-70 region 2 77 146 3.2E-18 T 14-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 D521_1926 b1396437576fbb078e52de3429e393d4 313 SUPERFAMILY SSF88946 39 146 8.37E-39 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 D521_1926 b1396437576fbb078e52de3429e393d4 313 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 278 304 - T 14-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 D521_0691 04e5e261a99bdde33282ef3f9306e25f 101 Pfam PF03795 YCII-related domain 1 84 1.1E-13 T 14-10-2018 IPR005545 YCII-related D521_0691 04e5e261a99bdde33282ef3f9306e25f 101 Gene3D G3DSA:3.30.70.1060 1 95 9.4E-28 T 14-10-2018 D521_0691 04e5e261a99bdde33282ef3f9306e25f 101 SUPERFAMILY SSF54909 1 88 1.98E-19 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel D521_0287 b98e522b816cfc561f7f53d1673e6bb1 59 Pfam PF03966 Trm112p-like protein 2 40 3.9E-11 T 14-10-2018 IPR005651 Trm112-like D521_0287 b98e522b816cfc561f7f53d1673e6bb1 59 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 28.11 T 14-10-2018 IPR038053 Uncharacterised protein family UPF0434 D521_0287 b98e522b816cfc561f7f53d1673e6bb1 59 SUPERFAMILY SSF158997 1 55 1.96E-21 T 14-10-2018 D521_0287 b98e522b816cfc561f7f53d1673e6bb1 59 Gene3D G3DSA:2.20.25.10 8 59 1.4E-24 T 14-10-2018 D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 Pfam PF00994 Probable molybdopterin binding domain 207 349 4.4E-28 T 14-10-2018 IPR001453 MoaB/Mog domain D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 SMART SM00852 207 351 2.9E-40 T 14-10-2018 IPR001453 MoaB/Mog domain D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 Gene3D G3DSA:3.40.980.10 202 360 1.9E-131 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 Pfam PF03454 MoeA C-terminal region (domain IV) 365 436 6.2E-20 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 Gene3D G3DSA:2.40.340.10 361 431 1.9E-131 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 SUPERFAMILY SSF63867 362 440 4.45E-25 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 SUPERFAMILY SSF63882 37 203 4.45E-45 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 Pfam PF03453 MoeA N-terminal region (domain I and II) 20 194 2.3E-37 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 Gene3D G3DSA:2.170.190.11 72 168 1.9E-131 T 14-10-2018 D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 203 346 3.4E-30 T 14-10-2018 IPR001453 MoaB/Mog domain D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 SUPERFAMILY SSF53218 204 354 8.77E-41 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily D521_1441 3bf3810dc78933ab078ae7d20b91372b 440 Gene3D G3DSA:3.90.105.10 49 201 1.9E-131 T 14-10-2018 D521_0560 6d7e5d31c13315ba411b629cdf5a9c59 351 PIRSF PIRSF002825 12 351 1.6E-77 T 14-10-2018 IPR026045 Ferric binding protein D521_0560 6d7e5d31c13315ba411b629cdf5a9c59 351 Gene3D G3DSA:3.40.190.10 34 313 2.3E-115 T 14-10-2018 D521_0560 6d7e5d31c13315ba411b629cdf5a9c59 351 Gene3D G3DSA:3.40.190.10 136 349 2.3E-115 T 14-10-2018 D521_0560 6d7e5d31c13315ba411b629cdf5a9c59 351 SUPERFAMILY SSF53850 28 341 2.31E-74 T 14-10-2018 D521_0560 6d7e5d31c13315ba411b629cdf5a9c59 351 Pfam PF13416 Bacterial extracellular solute-binding protein 47 312 1.1E-22 T 14-10-2018 IPR006059 Bacterial extracellular solute-binding protein D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 Gene3D G3DSA:3.30.572.10 1 264 2.4E-130 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 Pfam PF00303 Thymidylate synthase 3 264 1.5E-123 T 14-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 3.9E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 3.9E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 3.9E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 3.9E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 3.9E-47 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 14-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 39.107 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 SUPERFAMILY SSF55831 1 264 4.19E-127 T 14-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 84 7.4E-38 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1446 07d2c90fe4aa90ae7806dd47c62cbbf1 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 86 264 2.5E-95 T 14-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 D521_1168 bcad2ee6241c510afac042ed1934af1f 284 SUPERFAMILY SSF56176 1 174 4.69E-53 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 D521_1168 bcad2ee6241c510afac042ed1934af1f 284 Gene3D G3DSA:3.30.465.10 58 175 1.5E-40 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 D521_1168 bcad2ee6241c510afac042ed1934af1f 284 Pfam PF03450 CO dehydrogenase flavoprotein C-terminal domain 183 280 3.8E-16 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal D521_1168 bcad2ee6241c510afac042ed1934af1f 284 Gene3D G3DSA:3.30.43.10 1 57 2.8E-21 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 D521_1168 bcad2ee6241c510afac042ed1934af1f 284 Gene3D G3DSA:3.30.390.50 180 284 1.0E-22 T 14-10-2018 D521_1168 bcad2ee6241c510afac042ed1934af1f 284 SUPERFAMILY SSF55447 181 282 1.01E-17 T 14-10-2018 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily D521_1168 bcad2ee6241c510afac042ed1934af1f 284 SMART SM01092 181 282 1.1E-16 T 14-10-2018 IPR005107 CO dehydrogenase flavoprotein, C-terminal D521_1168 bcad2ee6241c510afac042ed1934af1f 284 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 5 174 1.9E-45 T 14-10-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 D521_0098 951c0552e58a1e9605d9bdbda5e57ff5 248 Pfam PF04333 MlaA lipoprotein 34 227 7.7E-74 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 D521_0098 951c0552e58a1e9605d9bdbda5e57ff5 248 PRINTS PR01805 VacJ lipoprotein signature 139 156 1.9E-28 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 D521_0098 951c0552e58a1e9605d9bdbda5e57ff5 248 PRINTS PR01805 VacJ lipoprotein signature 35 48 1.9E-28 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 D521_0098 951c0552e58a1e9605d9bdbda5e57ff5 248 PRINTS PR01805 VacJ lipoprotein signature 52 68 1.9E-28 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 D521_0098 951c0552e58a1e9605d9bdbda5e57ff5 248 PRINTS PR01805 VacJ lipoprotein signature 103 120 1.9E-28 T 14-10-2018 IPR007428 MlaA lipoprotein GO:0016020 D521_1422 e604211deccbf425b7e767b5250a43d5 601 SUPERFAMILY SSF50447 182 277 7.9E-20 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily D521_1422 e604211deccbf425b7e767b5250a43d5 601 TIGRFAM TIGR01393 lepA: elongation factor 4 4 600 3.8E-297 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 D521_1422 e604211deccbf425b7e767b5250a43d5 601 SUPERFAMILY SSF52540 3 205 1.1E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1422 e604211deccbf425b7e767b5250a43d5 601 SMART SM00838 403 490 5.3E-4 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like D521_1422 e604211deccbf425b7e767b5250a43d5 601 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 42 57 - T 14-10-2018 IPR031157 Tr-type G domain, conserved site D521_1422 e604211deccbf425b7e767b5250a43d5 601 Gene3D G3DSA:3.30.70.3380 373 483 1.6E-41 T 14-10-2018 D521_1422 e604211deccbf425b7e767b5250a43d5 601 Pfam PF00679 Elongation factor G C-terminus 404 489 3.8E-23 T 14-10-2018 IPR000640 Elongation factor EFG, domain V-like D521_1422 e604211deccbf425b7e767b5250a43d5 601 Gene3D G3DSA:3.40.50.300 2 185 6.9E-73 T 14-10-2018 D521_1422 e604211deccbf425b7e767b5250a43d5 601 PRINTS PR00315 GTP-binding elongation factor signature 90 101 2.4E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_1422 e604211deccbf425b7e767b5250a43d5 601 PRINTS PR00315 GTP-binding elongation factor signature 6 19 2.4E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_1422 e604211deccbf425b7e767b5250a43d5 601 PRINTS PR00315 GTP-binding elongation factor signature 49 57 2.4E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_1422 e604211deccbf425b7e767b5250a43d5 601 PRINTS PR00315 GTP-binding elongation factor signature 74 84 2.4E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_1422 e604211deccbf425b7e767b5250a43d5 601 PRINTS PR00315 GTP-binding elongation factor signature 126 135 2.4E-14 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_1422 e604211deccbf425b7e767b5250a43d5 601 SUPERFAMILY SSF54980 404 498 2.3E-26 T 14-10-2018 IPR035647 EF-G domain III/V-like D521_1422 e604211deccbf425b7e767b5250a43d5 601 Pfam PF00009 Elongation factor Tu GTP binding domain 4 181 1.6E-53 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_1422 e604211deccbf425b7e767b5250a43d5 601 Pfam PF06421 GTP-binding protein LepA C-terminus 492 598 4.6E-50 T 14-10-2018 IPR013842 GTP-binding protein LepA, C-terminal D521_1422 e604211deccbf425b7e767b5250a43d5 601 Gene3D G3DSA:2.40.30.10 186 282 3.0E-32 T 14-10-2018 D521_1422 e604211deccbf425b7e767b5250a43d5 601 Pfam PF03144 Elongation factor Tu domain 2 205 275 5.0E-10 T 14-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 D521_1422 e604211deccbf425b7e767b5250a43d5 601 Gene3D G3DSA:3.30.70.2570 484 558 1.3E-32 T 14-10-2018 IPR038363 LepA, C-terminal domain superfamily D521_1422 e604211deccbf425b7e767b5250a43d5 601 SUPERFAMILY SSF54980 297 375 1.55E-18 T 14-10-2018 IPR035647 EF-G domain III/V-like D521_1422 e604211deccbf425b7e767b5250a43d5 601 Gene3D G3DSA:3.30.70.870 291 372 2.2E-35 T 14-10-2018 D521_1422 e604211deccbf425b7e767b5250a43d5 601 Hamap MF_00071 Elongation factor 4 [lepA]. 1 601 301.961 T 14-10-2018 IPR006297 Elongation factor 4 GO:0005525 D521_1422 e604211deccbf425b7e767b5250a43d5 601 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 175 6.1E-18 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 D521_0642 0047feeb00e680479c60a033ffb90060 388 SUPERFAMILY SSF52172 1 122 2.34E-8 T 14-10-2018 IPR011006 CheY-like superfamily D521_0642 0047feeb00e680479c60a033ffb90060 388 SUPERFAMILY SSF52540 133 372 1.52E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0642 0047feeb00e680479c60a033ffb90060 388 Pfam PF13614 AAA domain 133 286 7.5E-14 T 14-10-2018 IPR025669 AAA domain D521_0642 0047feeb00e680479c60a033ffb90060 388 Gene3D G3DSA:3.40.50.300 132 373 4.7E-44 T 14-10-2018 D521_0642 0047feeb00e680479c60a033ffb90060 388 Gene3D G3DSA:3.40.50.2300 1 124 5.2E-19 T 14-10-2018 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 Gene3D G3DSA:1.10.150.80 539 623 2.1E-25 T 14-10-2018 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 Pfam PF00570 HRDC domain 548 614 2.0E-22 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 SMART SM00487 23 221 5.3E-22 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 Pfam PF00270 DEAD/DEAH box helicase 30 190 2.8E-16 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 Gene3D G3DSA:3.40.50.300 214 346 3.3E-40 T 14-10-2018 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 SMART SM00490 256 337 1.0E-25 T 14-10-2018 IPR001650 Helicase, C-terminal D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 SUPERFAMILY SSF47819 546 624 9.59E-24 T 14-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 SUPERFAMILY SSF52540 15 201 1.85E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 SMART SM00341 544 624 1.3E-17 T 14-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 SMART SM00956 418 522 3.1E-50 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 15 616 3.9E-247 T 14-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 Gene3D G3DSA:3.40.50.300 5 213 3.0E-77 T 14-10-2018 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 SUPERFAMILY SSF52540 213 465 7.3E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 Pfam PF16124 RecQ zinc-binding 349 411 1.7E-21 T 14-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 Gene3D G3DSA:1.10.10.10 347 533 8.5E-50 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 Pfam PF09382 RQC domain 414 526 2.4E-36 T 14-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 Pfam PF00271 Helicase conserved C-terminal domain 231 336 6.1E-15 T 14-10-2018 IPR001650 Helicase, C-terminal D521_0556 f14dd0a5b3bbd2eb7cc3707b7c814103 627 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 16 469 2.5E-155 T 14-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 D521_0858 7728ec8d0e846510ef2cf5c37307432d 255 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 8 167 8.1E-72 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 D521_0858 7728ec8d0e846510ef2cf5c37307432d 255 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 5.0E-5 T 14-10-2018 IPR001451 Hexapeptide repeat D521_0858 7728ec8d0e846510ef2cf5c37307432d 255 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 118 152 3.3E-6 T 14-10-2018 IPR001451 Hexapeptide repeat D521_0858 7728ec8d0e846510ef2cf5c37307432d 255 Gene3D G3DSA:1.10.3130.10 2 66 2.5E-21 T 14-10-2018 D521_0858 7728ec8d0e846510ef2cf5c37307432d 255 SUPERFAMILY SSF51161 7 169 2.91E-51 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily D521_0858 7728ec8d0e846510ef2cf5c37307432d 255 PIRSF PIRSF000441 1 244 1.1E-79 T 14-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 D521_0858 7728ec8d0e846510ef2cf5c37307432d 255 Gene3D G3DSA:2.160.10.10 67 185 2.9E-35 T 14-10-2018 D521_0467 3adfe8a7c4a7e3a406fc25a535d21846 364 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 201 212 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_0467 3adfe8a7c4a7e3a406fc25a535d21846 364 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 12 323 46.969 T 14-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 D521_0467 3adfe8a7c4a7e3a406fc25a535d21846 364 Pfam PF13484 4Fe-4S double cluster binding domain 200 264 5.2E-20 T 14-10-2018 D521_0467 3adfe8a7c4a7e3a406fc25a535d21846 364 Pfam PF08331 Domain of unknown function (DUF1730) 67 148 3.1E-21 T 14-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 D521_0467 3adfe8a7c4a7e3a406fc25a535d21846 364 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 20 363 1.5E-134 T 14-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 D521_0467 3adfe8a7c4a7e3a406fc25a535d21846 364 SUPERFAMILY SSF46548 147 264 4.5E-19 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 SUPERFAMILY SSF52935 328 477 2.22E-35 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 Pfam PF02887 Pyruvate kinase, alpha/beta domain 363 475 1.1E-27 T 14-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 Pfam PF00224 Pyruvate kinase, barrel domain 3 343 2.6E-114 T 14-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 477 3.6E-150 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 Gene3D G3DSA:3.20.20.60 3 340 2.5E-157 T 14-10-2018 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 Gene3D G3DSA:3.40.1380.20 341 473 2.5E-157 T 14-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 SUPERFAMILY SSF51621 2 343 4.89E-85 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 SUPERFAMILY SSF50800 71 162 1.1E-25 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily D521_1811 8dcae049f3d04fc545c536c485bb9475 478 PRINTS PR01050 Pyruvate kinase family signature 274 298 1.0E-42 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 PRINTS PR01050 Pyruvate kinase family signature 318 334 1.0E-42 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 PRINTS PR01050 Pyruvate kinase family signature 60 76 1.0E-42 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 PRINTS PR01050 Pyruvate kinase family signature 299 317 1.0E-42 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 PRINTS PR01050 Pyruvate kinase family signature 185 199 1.0E-42 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 PRINTS PR01050 Pyruvate kinase family signature 249 273 1.0E-42 T 14-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_1811 8dcae049f3d04fc545c536c485bb9475 478 Gene3D G3DSA:2.40.33.10 71 167 2.5E-157 T 14-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 D521_0689 47a1e21b7e391c1d21423a709f5968d2 653 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 2 653 51.072 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 D521_0689 47a1e21b7e391c1d21423a709f5968d2 653 Pfam PF13193 AMP-binding enzyme C-terminal domain 537 618 6.9E-26 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain D521_0689 47a1e21b7e391c1d21423a709f5968d2 653 SUPERFAMILY SSF56801 8 649 2.62E-171 T 14-10-2018 D521_0689 47a1e21b7e391c1d21423a709f5968d2 653 Gene3D G3DSA:3.30.300.30 524 653 6.5E-28 T 14-10-2018 D521_0689 47a1e21b7e391c1d21423a709f5968d2 653 ProSitePatterns PS00455 Putative AMP-binding domain signature. 260 271 - T 14-10-2018 IPR020845 AMP-binding, conserved site D521_0689 47a1e21b7e391c1d21423a709f5968d2 653 Pfam PF00501 AMP-binding enzyme 84 528 1.7E-92 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 D521_0689 47a1e21b7e391c1d21423a709f5968d2 653 Gene3D G3DSA:3.40.50.12780 48 521 8.5E-101 T 14-10-2018 D521_0689 47a1e21b7e391c1d21423a709f5968d2 653 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 22 651 3.5E-294 T 14-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 D521_0689 47a1e21b7e391c1d21423a709f5968d2 653 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 25 80 1.5E-20 T 14-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 D521_1418 8b06654bc3f3ea30c8326513e635789d 244 Pfam PF02565 Recombination protein O C terminal 87 233 5.6E-24 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 D521_1418 8b06654bc3f3ea30c8326513e635789d 244 Gene3D G3DSA:1.20.1440.120 84 244 3.2E-43 T 14-10-2018 D521_1418 8b06654bc3f3ea30c8326513e635789d 244 SUPERFAMILY SSF57863 89 224 6.02E-9 T 14-10-2018 IPR037278 ARFGAP/RecO-like zinc finger D521_1418 8b06654bc3f3ea30c8326513e635789d 244 Gene3D G3DSA:2.40.50.140 7 80 3.0E-31 T 14-10-2018 D521_1418 8b06654bc3f3ea30c8326513e635789d 244 Hamap MF_00201 DNA repair protein RecO [recO]. 5 242 21.914 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 D521_1418 8b06654bc3f3ea30c8326513e635789d 244 SUPERFAMILY SSF50249 9 79 6.17E-14 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1418 8b06654bc3f3ea30c8326513e635789d 244 TIGRFAM TIGR00613 reco: DNA repair protein RecO 11 168 1.5E-27 T 14-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 D521_1418 8b06654bc3f3ea30c8326513e635789d 244 Pfam PF11967 Recombination protein O N terminal 8 80 1.1E-23 T 14-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal D521_1804 93adfaf935ded2d8018a67d579b876be 809 SMART SM00388 306 372 9.4E-18 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_1804 93adfaf935ded2d8018a67d579b876be 809 Gene3D G3DSA:3.30.565.10 371 540 1.3E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1804 93adfaf935ded2d8018a67d579b876be 809 Gene3D G3DSA:3.40.50.2300 562 690 4.6E-27 T 14-10-2018 D521_1804 93adfaf935ded2d8018a67d579b876be 809 SUPERFAMILY SSF47384 291 373 7.85E-18 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 D521_1804 93adfaf935ded2d8018a67d579b876be 809 Pfam PF00072 Response regulator receiver domain 575 683 1.8E-20 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1804 93adfaf935ded2d8018a67d579b876be 809 SUPERFAMILY SSF55874 361 535 3.27E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1804 93adfaf935ded2d8018a67d579b876be 809 SUPERFAMILY SSF47226 668 780 6.28E-8 T 14-10-2018 IPR036641 HPT domain superfamily GO:0000160 D521_1804 93adfaf935ded2d8018a67d579b876be 809 SMART SM00448 572 685 5.6E-21 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1804 93adfaf935ded2d8018a67d579b876be 809 Gene3D G3DSA:3.40.190.10 29 240 5.2E-14 T 14-10-2018 D521_1804 93adfaf935ded2d8018a67d579b876be 809 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 420 535 1.3E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_1804 93adfaf935ded2d8018a67d579b876be 809 Gene3D G3DSA:1.10.287.130 274 370 1.2E-22 T 14-10-2018 D521_1804 93adfaf935ded2d8018a67d579b876be 809 SMART SM00387 419 541 1.4E-20 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_1804 93adfaf935ded2d8018a67d579b876be 809 Gene3D G3DSA:3.40.190.10 125 213 5.2E-14 T 14-10-2018 D521_1804 93adfaf935ded2d8018a67d579b876be 809 SUPERFAMILY SSF52172 575 691 1.57E-27 T 14-10-2018 IPR011006 CheY-like superfamily D521_1804 93adfaf935ded2d8018a67d579b876be 809 Pfam PF00512 His Kinase A (phospho-acceptor) domain 306 372 9.1E-14 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_1804 93adfaf935ded2d8018a67d579b876be 809 SUPERFAMILY SSF53850 32 238 3.91E-10 T 14-10-2018 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 21 314 4.0E-106 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 2 315 35.15 T 14-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 Gene3D G3DSA:2.170.120.12 50 173 7.4E-83 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 SMART SM00662 20 230 7.2E-97 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 254 324 4.0E-33 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 Gene3D G3DSA:3.30.1360.10 15 223 7.4E-83 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 224 1.2E-22 T 14-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 SUPERFAMILY SSF47789 249 323 9.55E-27 T 14-10-2018 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 250 306 2.1E-24 T 14-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 61 150 6.4E-25 T 14-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 SUPERFAMILY SSF56553 50 174 9.42E-43 T 14-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 SUPERFAMILY SSF55257 5 228 3.34E-29 T 14-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0078 af3eb662c3fa1eaa41d2dfa15519fa19 326 Gene3D G3DSA:1.10.150.20 243 326 2.4E-36 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Gene3D G3DSA:3.30.70.20 148 230 1.9E-20 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 SUPERFAMILY SSF54292 15 111 1.39E-28 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 SUPERFAMILY SSF53706 241 847 1.13E-197 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 SMART SM00926 239 292 1.9E-19 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 SUPERFAMILY SSF54862 88 232 1.99E-27 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Gene3D G3DSA:2.40.40.20 819 940 9.7E-41 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Gene3D G3DSA:2.20.25.90 240 292 1.5E-22 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Gene3D G3DSA:3.10.20.740 15 129 7.1E-25 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 212 223 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 14 88 1.3E-17 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 SUPERFAMILY SSF50692 793 940 2.28E-42 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily D521_0695 038c4358a7efcb4a361e64179351e1fa 963 PIRSF PIRSF036643 10 958 0.0 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Pfam PF01568 Molydopterin dinucleotide binding domain 829 935 2.0E-26 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 684 701 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Pfam PF13187 4Fe-4S dicluster domain 168 226 5.3E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Gene3D G3DSA:3.40.50.740 323 786 8.1E-178 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Gene3D G3DSA:3.40.228.10 389 587 8.1E-178 T 14-10-2018 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 240 292 2.0E-17 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 245 937 1.2E-218 T 14-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 D521_0695 038c4358a7efcb4a361e64179351e1fa 963 Pfam PF00384 Molybdopterin oxidoreductase 295 739 1.6E-90 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_1284 477ec09a596fb86971b62650483025d7 326 Pfam PF08279 HTH domain 8 53 9.7E-6 T 14-10-2018 IPR013196 Helix-turn-helix, type 11 D521_1284 477ec09a596fb86971b62650483025d7 326 Pfam PF13280 WYL domain 148 317 9.6E-34 T 14-10-2018 IPR026881 WYL domain D521_1284 477ec09a596fb86971b62650483025d7 326 SUPERFAMILY SSF46785 3 45 9.42E-5 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1284 477ec09a596fb86971b62650483025d7 326 Gene3D G3DSA:1.10.10.10 1 63 4.3E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0484 5544784cb354b4fdcf58542ba13eb3e0 129 SUPERFAMILY SSF81301 1 109 1.57E-34 T 14-10-2018 D521_0484 5544784cb354b4fdcf58542ba13eb3e0 129 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 22.599 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS D521_0484 5544784cb354b4fdcf58542ba13eb3e0 129 Gene3D G3DSA:3.30.460.10 1 116 1.7E-34 T 14-10-2018 D521_0484 5544784cb354b4fdcf58542ba13eb3e0 129 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 2.6E-25 T 14-10-2018 D521_0484 5544784cb354b4fdcf58542ba13eb3e0 129 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 8.3E-33 T 14-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS D521_0323 b2ca77b8aeeb9432b7bcff75887c262a 616 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 334 2.2E-30 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 D521_0323 b2ca77b8aeeb9432b7bcff75887c262a 616 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 422 553 7.4E-26 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 D521_0323 b2ca77b8aeeb9432b7bcff75887c262a 616 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 439 458 - T 14-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 D521_0323 b2ca77b8aeeb9432b7bcff75887c262a 616 SUPERFAMILY SSF52518 376 585 3.12E-36 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0323 b2ca77b8aeeb9432b7bcff75887c262a 616 SUPERFAMILY SSF52467 201 369 3.84E-33 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily D521_0323 b2ca77b8aeeb9432b7bcff75887c262a 616 Gene3D G3DSA:3.40.50.970 1 181 5.4E-50 T 14-10-2018 D521_0323 b2ca77b8aeeb9432b7bcff75887c262a 616 Gene3D G3DSA:3.40.50.1220 205 368 1.0E-84 T 14-10-2018 D521_0323 b2ca77b8aeeb9432b7bcff75887c262a 616 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 172 3.1E-44 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 D521_0323 b2ca77b8aeeb9432b7bcff75887c262a 616 SUPERFAMILY SSF52518 1 179 5.44E-40 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0323 b2ca77b8aeeb9432b7bcff75887c262a 616 Gene3D G3DSA:3.40.50.970 369 553 1.0E-84 T 14-10-2018 D521_1929 674d6e7f8cd080e58e92bc9f1de3c62e 376 Pfam PF02628 Cytochrome oxidase assembly protein 36 356 1.9E-79 T 14-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 D521_1173 58858f06d5d4c77e8fa8a99b96b150ce 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 37 53 5.3E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 D521_1173 58858f06d5d4c77e8fa8a99b96b150ce 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 293 306 5.3E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 D521_1173 58858f06d5d4c77e8fa8a99b96b150ce 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 100 110 5.3E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 D521_1173 58858f06d5d4c77e8fa8a99b96b150ce 411 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 59 75 5.3E-6 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 D521_1173 58858f06d5d4c77e8fa8a99b96b150ce 411 SUPERFAMILY SSF53822 36 384 1.85E-84 T 14-10-2018 IPR028082 Periplasmic binding protein-like I D521_1173 58858f06d5d4c77e8fa8a99b96b150ce 411 Pfam PF13458 Periplasmic binding protein 36 377 8.9E-74 T 14-10-2018 IPR028081 Leucine-binding protein domain D521_1173 58858f06d5d4c77e8fa8a99b96b150ce 411 Gene3D G3DSA:3.40.50.2300 59 370 4.3E-90 T 14-10-2018 D521_1173 58858f06d5d4c77e8fa8a99b96b150ce 411 Gene3D G3DSA:3.40.50.2300 157 377 4.3E-90 T 14-10-2018 D521_1208 1b9be5f00adc803138abf33282f3d502 151 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 10 151 48.146 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 D521_1208 1b9be5f00adc803138abf33282f3d502 151 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 55 92 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 D521_1208 1b9be5f00adc803138abf33282f3d502 151 SUPERFAMILY SSF53927 3 151 1.46E-56 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 D521_1208 1b9be5f00adc803138abf33282f3d502 151 Gene3D G3DSA:3.40.140.10 1 151 2.8E-62 T 14-10-2018 D521_1208 1b9be5f00adc803138abf33282f3d502 151 Pfam PF14437 MafB19-like deaminase 7 151 3.0E-33 T 14-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 D521_1485 c29b2553215c9b41521f112b92cbe8a1 190 Pfam PF00691 OmpA family 83 177 6.1E-22 T 14-10-2018 IPR006665 OmpA-like domain D521_1485 c29b2553215c9b41521f112b92cbe8a1 190 PRINTS PR01021 OMPA domain signature 113 128 1.2E-20 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 D521_1485 c29b2553215c9b41521f112b92cbe8a1 190 PRINTS PR01021 OMPA domain signature 83 105 1.2E-20 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 D521_1485 c29b2553215c9b41521f112b92cbe8a1 190 PRINTS PR01021 OMPA domain signature 128 144 1.2E-20 T 14-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 D521_1485 c29b2553215c9b41521f112b92cbe8a1 190 SUPERFAMILY SSF103088 73 183 3.4E-36 T 14-10-2018 IPR036737 OmpA-like domain superfamily D521_1485 c29b2553215c9b41521f112b92cbe8a1 190 ProSitePatterns PS01068 OmpA-like domain. 115 159 - T 14-10-2018 IPR006690 Outer membrane protein, OmpA-like, conserved site GO:0009279|GO:0016021 D521_1485 c29b2553215c9b41521f112b92cbe8a1 190 Gene3D G3DSA:3.30.1330.60 63 188 3.7E-39 T 14-10-2018 IPR036737 OmpA-like domain superfamily D521_0553 49b9939a2e2720616e5f0a934d298bf8 770 SMART SM00843 704 769 1.2E-34 T 14-10-2018 IPR018541 FtsK gamma domain D521_0553 49b9939a2e2720616e5f0a934d298bf8 770 Pfam PF09397 Ftsk gamma domain 706 765 5.5E-24 T 14-10-2018 IPR018541 FtsK gamma domain D521_0553 49b9939a2e2720616e5f0a934d298bf8 770 Pfam PF01580 FtsK/SpoIIIE family 393 602 5.5E-63 T 14-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 D521_0553 49b9939a2e2720616e5f0a934d298bf8 770 Gene3D G3DSA:3.30.980.40 285 389 5.3E-29 T 14-10-2018 D521_0553 49b9939a2e2720616e5f0a934d298bf8 770 SUPERFAMILY SSF52540 386 674 1.99E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0553 49b9939a2e2720616e5f0a934d298bf8 770 SUPERFAMILY SSF46785 704 768 4.54E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0553 49b9939a2e2720616e5f0a934d298bf8 770 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 28 206 1.8E-48 T 14-10-2018 IPR025199 DNA translocase FtsK, 4TM region D521_0553 49b9939a2e2720616e5f0a934d298bf8 770 Gene3D G3DSA:1.10.10.10 701 765 7.8E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0553 49b9939a2e2720616e5f0a934d298bf8 770 Gene3D G3DSA:3.40.50.300 390 688 1.9E-113 T 14-10-2018 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 460 478 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 195 206 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 SUPERFAMILY SSF47831 28 144 4.45E-28 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 Pfam PF05524 PEP-utilising enzyme, N-terminal 6 129 1.5E-27 T 14-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 SUPERFAMILY SSF51621 261 559 2.88E-93 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 Gene3D G3DSA:3.20.20.60 245 583 9.9E-106 T 14-10-2018 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 Gene3D G3DSA:1.10.274.10 24 149 3.6E-72 T 14-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 263 554 3.0E-103 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 460 475 1.4E-24 T 14-10-2018 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 304 323 1.4E-24 T 14-10-2018 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 477 492 1.4E-24 T 14-10-2018 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 513 525 1.4E-24 T 14-10-2018 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 SUPERFAMILY SSF52009 128 256 4.19E-31 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 Pfam PF00391 PEP-utilising enzyme, mobile domain 166 236 7.7E-23 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 PIRSF PIRSF000732 1 583 1.6E-199 T 14-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 Gene3D G3DSA:3.50.30.10 7 244 3.6E-72 T 14-10-2018 D521_1949 81a278ae6aae8839ceb3e4de59e4ffbe 583 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 5 568 4.1E-157 T 14-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 D521_1992 16c145ebd1dd3eebd7146b02748b4590 138 Gene3D G3DSA:1.10.10.10 1 137 2.1E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1992 16c145ebd1dd3eebd7146b02748b4590 138 SMART SM00347 23 123 5.4E-23 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 D521_1992 16c145ebd1dd3eebd7146b02748b4590 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 8.3E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 D521_1992 16c145ebd1dd3eebd7146b02748b4590 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 8.3E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 D521_1992 16c145ebd1dd3eebd7146b02748b4590 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 8.3E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 D521_1992 16c145ebd1dd3eebd7146b02748b4590 138 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 8.3E-9 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 D521_1992 16c145ebd1dd3eebd7146b02748b4590 138 SUPERFAMILY SSF46785 5 137 1.18E-30 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1992 16c145ebd1dd3eebd7146b02748b4590 138 Pfam PF01047 MarR family 30 87 1.4E-15 T 14-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 D521_1992 16c145ebd1dd3eebd7146b02748b4590 138 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 96 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site D521_0272 683a4af524e967e68e4ca6fe8430a98c 96 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 10 86 3.3E-8 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family D521_0272 683a4af524e967e68e4ca6fe8430a98c 96 Gene3D G3DSA:3.30.2310.20 3 96 1.2E-22 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily D521_0272 683a4af524e967e68e4ca6fe8430a98c 96 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 7 85 5.0E-12 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family D521_0272 683a4af524e967e68e4ca6fe8430a98c 96 SUPERFAMILY SSF143011 3 84 3.01E-18 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 PIRSF PIRSF036643 831 994 3.8E-16 T 14-10-2018 D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 PIRSF PIRSF036643 25 608 3.6E-111 T 14-10-2018 D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 Gene3D G3DSA:3.40.228.10 213 412 2.2E-126 T 14-10-2018 D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 37 66 7.2E-5 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 Pfam PF00384 Molybdopterin oxidoreductase 136 590 1.5E-53 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 Gene3D G3DSA:2.20.25.90 80 132 5.3E-11 T 14-10-2018 D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 80 130 2.3E-10 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 Gene3D G3DSA:3.40.50.740 145 646 2.2E-126 T 14-10-2018 D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 SUPERFAMILY SSF53706 78 644 6.54E-193 T 14-10-2018 D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 SUPERFAMILY SSF50692 829 992 1.2E-40 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 SMART SM00926 79 133 6.6E-12 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 Gene3D G3DSA:2.40.40.20 805 993 6.0E-42 T 14-10-2018 D521_1189 2cd1de0e90a8dea3b91b0e6c0f2b9e3f 994 Pfam PF01568 Molydopterin dinucleotide binding domain 860 986 4.2E-20 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 D521_1988 48cfe43ad75f3c60bca78dc35a4932d9 511 SUPERFAMILY SSF56954 10 488 9.81E-98 T 14-10-2018 D521_1988 48cfe43ad75f3c60bca78dc35a4932d9 511 Gene3D G3DSA:1.20.1600.10 73 486 6.0E-112 T 14-10-2018 D521_1988 48cfe43ad75f3c60bca78dc35a4932d9 511 Gene3D G3DSA:2.20.200.10 121 374 6.0E-112 T 14-10-2018 D521_1988 48cfe43ad75f3c60bca78dc35a4932d9 511 Pfam PF02321 Outer membrane efflux protein 304 483 1.5E-23 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_1988 48cfe43ad75f3c60bca78dc35a4932d9 511 Pfam PF02321 Outer membrane efflux protein 86 274 8.2E-20 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_1988 48cfe43ad75f3c60bca78dc35a4932d9 511 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 16 485 1.2E-127 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 D521_1723 a1a2a7979db286fc2c6ff9c45e73f608 209 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 3 192 1.6E-71 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 D521_1723 a1a2a7979db286fc2c6ff9c45e73f608 209 SUPERFAMILY SSF53328 4 199 8.9E-65 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_1723 a1a2a7979db286fc2c6ff9c45e73f608 209 Pfam PF00551 Formyl transferase 4 182 2.0E-59 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_1723 a1a2a7979db286fc2c6ff9c45e73f608 209 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 30.637 T 14-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 D521_1723 a1a2a7979db286fc2c6ff9c45e73f608 209 Gene3D G3DSA:3.40.50.170 1 204 6.9E-79 T 14-10-2018 D521_1723 a1a2a7979db286fc2c6ff9c45e73f608 209 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 14-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_0719 502fb10c73fabf6ac56cfc351ceaa0be 216 SUPERFAMILY SSF52540 13 198 4.19E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0719 502fb10c73fabf6ac56cfc351ceaa0be 216 ProSitePatterns PS00856 Guanylate kinase-like signature. 50 67 - T 14-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 D521_0719 502fb10c73fabf6ac56cfc351ceaa0be 216 Gene3D G3DSA:3.40.50.300 20 193 4.5E-65 T 14-10-2018 D521_0719 502fb10c73fabf6ac56cfc351ceaa0be 216 Pfam PF00625 Guanylate kinase 18 194 1.3E-49 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit D521_0719 502fb10c73fabf6ac56cfc351ceaa0be 216 Hamap MF_00328 Guanylate kinase [gmk]. 14 197 35.556 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 D521_0719 502fb10c73fabf6ac56cfc351ceaa0be 216 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 17 194 2.5E-71 T 14-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 D521_0719 502fb10c73fabf6ac56cfc351ceaa0be 216 Gene3D G3DSA:3.30.63.10 47 106 4.5E-65 T 14-10-2018 D521_0719 502fb10c73fabf6ac56cfc351ceaa0be 216 SMART SM00072 15 197 1.2E-60 T 14-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 SUPERFAMILY SSF53244 316 473 7.51E-41 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 SUPERFAMILY SSF53623 91 315 1.96E-69 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 Pfam PF01225 Mur ligase family, catalytic domain 7 105 1.1E-26 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 Gene3D G3DSA:3.90.190.20 315 478 2.3E-43 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 Gene3D G3DSA:3.40.50.720 6 93 3.3E-30 T 14-10-2018 D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 407 9.4E-20 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 Pfam PF08245 Mur ligase middle domain 110 297 2.0E-28 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 7 469 1.3E-160 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 SUPERFAMILY SSF51984 6 92 4.58E-27 T 14-10-2018 D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 Gene3D G3DSA:3.40.1190.10 94 314 5.4E-78 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0171 ae66d97bb2bb88f187908137f69c82c8 478 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 478 42.05 T 14-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 4 156 2.7E-49 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 4 150 3.3E-46 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 4.3E-31 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 139 151 4.3E-31 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 84 100 4.3E-31 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 62 78 4.3E-31 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 108 127 4.3E-31 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 154 44.753 T 14-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 SUPERFAMILY SSF53098 1 157 8.09E-49 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 Gene3D G3DSA:3.30.420.10 3 158 1.3E-46 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_1872 fd1bbf3a01817c64083cdc884105c5e7 173 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 114 148 - T 14-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 D521_1778 69c5a799e6c9cc655fdfbb6239f0d5c1 384 Pfam PF03054 tRNA methyl transferase 29 382 5.3E-130 T 14-10-2018 D521_1778 69c5a799e6c9cc655fdfbb6239f0d5c1 384 Gene3D G3DSA:3.40.50.620 18 233 8.9E-92 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1778 69c5a799e6c9cc655fdfbb6239f0d5c1 384 SUPERFAMILY SSF52402 27 265 8.38E-56 T 14-10-2018 D521_1778 69c5a799e6c9cc655fdfbb6239f0d5c1 384 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 28 383 38.529 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 D521_1778 69c5a799e6c9cc655fdfbb6239f0d5c1 384 Gene3D G3DSA:2.30.30.280 234 301 2.0E-26 T 14-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 D521_1778 69c5a799e6c9cc655fdfbb6239f0d5c1 384 Gene3D G3DSA:2.40.30.10 303 384 2.2E-21 T 14-10-2018 D521_1778 69c5a799e6c9cc655fdfbb6239f0d5c1 384 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 29 382 3.2E-127 T 14-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 D521_2013 ea15d0300b2acea247e189991d4f6d7e 379 PIRSF PIRSF000443 4 379 3.7E-140 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 D521_2013 ea15d0300b2acea247e189991d4f6d7e 379 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 3 372 29.487 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 D521_2013 ea15d0300b2acea247e189991d4f6d7e 379 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 15 371 1.5E-139 T 14-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 D521_2013 ea15d0300b2acea247e189991d4f6d7e 379 Gene3D G3DSA:3.40.50.1820 19 360 4.1E-138 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_2013 ea15d0300b2acea247e189991d4f6d7e 379 Gene3D G3DSA:1.10.1740.110 180 290 4.1E-138 T 14-10-2018 D521_2013 ea15d0300b2acea247e189991d4f6d7e 379 Pfam PF00561 alpha/beta hydrolase fold 44 359 1.7E-34 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_2013 ea15d0300b2acea247e189991d4f6d7e 379 SUPERFAMILY SSF53474 11 373 2.09E-103 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0189 7bcfed25a7f1df3088bf760cd4ba7b43 164 Gene3D G3DSA:1.10.10.10 79 164 1.5E-26 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0189 7bcfed25a7f1df3088bf760cd4ba7b43 164 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 79 161 6.8E-21 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 D521_0189 7bcfed25a7f1df3088bf760cd4ba7b43 164 SUPERFAMILY SSF53155 9 84 3.65E-6 T 14-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 D521_0189 7bcfed25a7f1df3088bf760cd4ba7b43 164 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 81 163 1.4E-24 T 14-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 D521_0189 7bcfed25a7f1df3088bf760cd4ba7b43 164 SUPERFAMILY SSF46767 78 163 3.27E-23 T 14-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 D521_0837 429ca5d9578a470c559fc91f719dc2fc 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 1.8E-25 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 D521_0837 429ca5d9578a470c559fc91f719dc2fc 65 Pfam PF01632 Ribosomal protein L35 2 62 3.9E-24 T 14-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0837 429ca5d9578a470c559fc91f719dc2fc 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.423 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 D521_0837 429ca5d9578a470c559fc91f719dc2fc 65 SUPERFAMILY SSF143034 2 64 5.23E-23 T 14-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0837 429ca5d9578a470c559fc91f719dc2fc 65 Gene3D G3DSA:2.40.50.530 1 65 3.7E-21 T 14-10-2018 D521_0837 429ca5d9578a470c559fc91f719dc2fc 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 14-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0837 429ca5d9578a470c559fc91f719dc2fc 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 7.3E-17 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 D521_0837 429ca5d9578a470c559fc91f719dc2fc 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 7.3E-17 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 D521_0837 429ca5d9578a470c559fc91f719dc2fc 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 7.3E-17 T 14-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 Pfam PF01043 SecA preprotein cross-linking domain 233 361 1.1E-37 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 SMART SM00957 6 405 5.2E-296 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 SUPERFAMILY SSF52540 5 418 2.66E-83 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 SUPERFAMILY SSF81886 631 909 5.23E-77 T 14-10-2018 IPR036266 SecA, Wing/Scaffold superfamily D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 Gene3D G3DSA:3.40.50.300 421 629 1.6E-84 T 14-10-2018 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 SUPERFAMILY SSF52540 420 628 1.27E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 SMART SM00958 228 361 9.8E-75 T 14-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 842 19.806 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 Gene3D G3DSA:3.10.450.50 863 920 4.8E-9 T 14-10-2018 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 Gene3D G3DSA:3.90.1440.10 229 371 3.7E-175 T 14-10-2018 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 827 0.0 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 Gene3D G3DSA:3.40.50.300 22 418 3.7E-175 T 14-10-2018 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 ProSitePatterns PS01312 SecA family signature. 503 518 - T 14-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 SUPERFAMILY SSF81767 227 371 4.97E-43 T 14-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 Pfam PF02810 SEC-C motif 901 918 4.0E-9 T 14-10-2018 IPR004027 SEC-C motif D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 Pfam PF07517 SecA DEAD-like domain 7 405 2.2E-129 T 14-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 Pfam PF07516 SecA Wing and Scaffold domain 627 840 6.2E-62 T 14-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 PRINTS PR00906 SecA protein signature 379 396 2.3E-67 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 PRINTS PR00906 SecA protein signature 170 190 2.3E-67 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 PRINTS PR00906 SecA protein signature 416 429 2.3E-67 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 PRINTS PR00906 SecA protein signature 63 87 2.3E-67 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 PRINTS PR00906 SecA protein signature 101 115 2.3E-67 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 PRINTS PR00906 SecA protein signature 342 364 2.3E-67 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 PRINTS PR00906 SecA protein signature 117 127 2.3E-67 T 14-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 D521_0179 1f3ec16c4726525d55e1ed616aa1b897 921 Gene3D G3DSA:1.10.3060.10 631 843 1.3E-70 T 14-10-2018 D521_1550 9f9b926f9c5e0556655723711af6734f 184 Pfam PF12915 Protein of unknown function (DUF3833) 19 183 2.3E-66 T 14-10-2018 IPR024409 Protein of unknown function DUF3833 D521_0386 16053c1580e943bd359286839f9a064c 272 SUPERFAMILY SSF54534 143 233 7.2E-21 T 14-10-2018 D521_0386 16053c1580e943bd359286839f9a064c 272 Gene3D G3DSA:3.10.50.40 140 237 8.7E-22 T 14-10-2018 D521_0386 16053c1580e943bd359286839f9a064c 272 SUPERFAMILY SSF109998 32 171 5.49E-15 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily D521_0386 16053c1580e943bd359286839f9a064c 272 Gene3D G3DSA:1.10.4030.30 33 132 9.8E-8 T 14-10-2018 D521_0386 16053c1580e943bd359286839f9a064c 272 Pfam PF13145 PPIC-type PPIASE domain 119 244 3.0E-18 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 D521_0386 16053c1580e943bd359286839f9a064c 272 Pfam PF13624 SurA N-terminal domain 12 92 6.4E-8 T 14-10-2018 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 1.9E-285 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 SUPERFAMILY SSF100934 508 607 2.75E-20 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 SUPERFAMILY SSF53067 189 383 6.22E-67 T 14-10-2018 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 SUPERFAMILY SSF100920 385 541 1.02E-59 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 Gene3D G3DSA:3.90.640.10 230 317 5.8E-163 T 14-10-2018 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 Pfam PF00012 Hsp70 protein 4 604 4.4E-259 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 Gene3D G3DSA:3.30.420.40 180 367 5.8E-163 T 14-10-2018 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 640 36.506 T 14-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 Gene3D G3DSA:1.20.1270.10 525 604 9.0E-24 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 Gene3D G3DSA:3.30.420.40 5 380 5.8E-163 T 14-10-2018 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 PRINTS PR00301 70kDa heat shock protein signature 3 16 6.0E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 PRINTS PR00301 70kDa heat shock protein signature 366 386 6.0E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 PRINTS PR00301 70kDa heat shock protein signature 335 351 6.0E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 PRINTS PR00301 70kDa heat shock protein signature 54 62 6.0E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 PRINTS PR00301 70kDa heat shock protein signature 199 209 6.0E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 PRINTS PR00301 70kDa heat shock protein signature 470 486 6.0E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 PRINTS PR00301 70kDa heat shock protein signature 31 43 6.0E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 PRINTS PR00301 70kDa heat shock protein signature 138 158 6.0E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 PRINTS PR00301 70kDa heat shock protein signature 389 408 6.0E-80 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 Gene3D G3DSA:2.60.34.10 384 524 4.1E-67 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 338 352 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 193 206 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 D521_1751 8d0b86365884c47fcb4c445b45b2fd5f 644 SUPERFAMILY SSF53067 4 184 2.88E-65 T 14-10-2018 D521_1327 36c935c1413793ae5447e2caa291b576 258 Pfam PF00970 Oxidoreductase FAD-binding domain 16 90 9.1E-8 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 D521_1327 36c935c1413793ae5447e2caa291b576 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 215 223 1.4E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 D521_1327 36c935c1413793ae5447e2caa291b576 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 136 145 1.4E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 D521_1327 36c935c1413793ae5447e2caa291b576 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 51 58 1.4E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 D521_1327 36c935c1413793ae5447e2caa291b576 258 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 111 130 1.4E-5 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 D521_1327 36c935c1413793ae5447e2caa291b576 258 SUPERFAMILY SSF63380 6 98 5.2E-22 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel D521_1327 36c935c1413793ae5447e2caa291b576 258 SUPERFAMILY SSF52343 102 256 4.85E-39 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain D521_1327 36c935c1413793ae5447e2caa291b576 258 Gene3D G3DSA:2.40.30.10 1 97 1.3E-25 T 14-10-2018 D521_1327 36c935c1413793ae5447e2caa291b576 258 Pfam PF00175 Oxidoreductase NAD-binding domain 114 228 1.2E-6 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 D521_1327 36c935c1413793ae5447e2caa291b576 258 Gene3D G3DSA:3.40.50.80 100 254 1.6E-41 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain D521_1145 260b1729687b620ab0424146a22e3648 285 Pfam PF03641 Possible lysine decarboxylase 148 277 1.5E-31 T 14-10-2018 IPR031100 LOG family D521_1145 260b1729687b620ab0424146a22e3648 285 Gene3D G3DSA:3.40.50.450 49 281 4.8E-58 T 14-10-2018 D521_1145 260b1729687b620ab0424146a22e3648 285 SUPERFAMILY SSF102405 45 279 3.21E-50 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 SUPERFAMILY SSF82693 149 339 1.54E-9 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 PRINTS PR00702 Acriflavin resistance protein family signature 17 41 2.8E-26 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 PRINTS PR00702 Acriflavin resistance protein family signature 45 63 2.8E-26 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 PRINTS PR00702 Acriflavin resistance protein family signature 402 426 2.8E-26 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 PRINTS PR00702 Acriflavin resistance protein family signature 482 505 2.8E-26 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 PRINTS PR00702 Acriflavin resistance protein family signature 457 480 2.8E-26 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 PRINTS PR00702 Acriflavin resistance protein family signature 348 371 2.8E-26 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 Pfam PF00873 AcrB/AcrD/AcrF family 20 1059 1.3E-144 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 Gene3D G3DSA:3.30.70.1430 582 690 4.3E-221 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 SUPERFAMILY SSF82693 578 692 2.62E-10 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 Gene3D G3DSA:3.30.2090.10 189 280 4.3E-221 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0405 cd9110553e93a66b22855062c908f6d7 1072 Gene3D G3DSA:3.30.2090.10 741 830 4.3E-221 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0405 cd9110553e93a66b22855062c908f6d7 1072 SUPERFAMILY SSF82866 307 508 2.62E-35 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 Gene3D G3DSA:1.20.1640.10 527 1057 4.3E-221 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 SUPERFAMILY SSF82714 192 274 2.35E-11 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0405 cd9110553e93a66b22855062c908f6d7 1072 Gene3D G3DSA:3.30.70.1430 47 838 4.3E-221 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 SUPERFAMILY SSF82866 831 1062 2.09E-39 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 SUPERFAMILY SSF82714 742 824 3.14E-8 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0405 cd9110553e93a66b22855062c908f6d7 1072 SUPERFAMILY SSF82693 47 131 7.5E-19 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 Gene3D G3DSA:1.20.1640.10 23 526 4.3E-221 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 Gene3D G3DSA:3.30.70.1440 691 902 4.3E-221 T 14-10-2018 D521_0405 cd9110553e93a66b22855062c908f6d7 1072 Gene3D G3DSA:3.30.70.1320 143 342 4.3E-221 T 14-10-2018 D521_1379 724e664d3b3188f963ea93786e1f5e26 331 Pfam PF13450 NAD(P)-binding Rossmann-like domain 13 69 3.7E-15 T 14-10-2018 D521_1379 724e664d3b3188f963ea93786e1f5e26 331 Gene3D G3DSA:3.90.660.10 48 289 3.1E-101 T 14-10-2018 D521_1379 724e664d3b3188f963ea93786e1f5e26 331 Gene3D G3DSA:3.50.50.60 10 323 3.1E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1379 724e664d3b3188f963ea93786e1f5e26 331 PRINTS PR00419 Adrenodoxin reductase family signature 32 45 5.3E-6 T 14-10-2018 D521_1379 724e664d3b3188f963ea93786e1f5e26 331 PRINTS PR00419 Adrenodoxin reductase family signature 9 31 5.3E-6 T 14-10-2018 D521_1379 724e664d3b3188f963ea93786e1f5e26 331 SUPERFAMILY SSF51905 8 324 2.43E-29 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0350 c9c536f549434d008fb5ea440d1f28cb 394 SUPERFAMILY SSF53822 25 384 6.06E-86 T 14-10-2018 IPR028082 Periplasmic binding protein-like I D521_0350 c9c536f549434d008fb5ea440d1f28cb 394 Gene3D G3DSA:3.40.50.2300 26 350 1.8E-85 T 14-10-2018 D521_0350 c9c536f549434d008fb5ea440d1f28cb 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 47 63 6.3E-9 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 D521_0350 c9c536f549434d008fb5ea440d1f28cb 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 66 84 6.3E-9 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 D521_0350 c9c536f549434d008fb5ea440d1f28cb 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 25 41 6.3E-9 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 D521_0350 c9c536f549434d008fb5ea440d1f28cb 394 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 279 292 6.3E-9 T 14-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 D521_0350 c9c536f549434d008fb5ea440d1f28cb 394 Pfam PF13458 Periplasmic binding protein 25 366 4.1E-68 T 14-10-2018 IPR028081 Leucine-binding protein domain D521_0350 c9c536f549434d008fb5ea440d1f28cb 394 Gene3D G3DSA:3.40.50.2300 148 276 1.8E-85 T 14-10-2018 D521_1547 92c7b4c6e8e0eb80cc28673aefbff999 326 SMART SM00829 13 324 1.3E-13 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 D521_1547 92c7b4c6e8e0eb80cc28673aefbff999 326 SUPERFAMILY SSF50129 5 151 5.33E-35 T 14-10-2018 IPR011032 GroES-like superfamily D521_1547 92c7b4c6e8e0eb80cc28673aefbff999 326 Pfam PF00107 Zinc-binding dehydrogenase 153 257 6.2E-25 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 D521_1547 92c7b4c6e8e0eb80cc28673aefbff999 326 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 63 77 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 D521_1547 92c7b4c6e8e0eb80cc28673aefbff999 326 Gene3D G3DSA:3.90.180.10 13 320 1.3E-100 T 14-10-2018 D521_1547 92c7b4c6e8e0eb80cc28673aefbff999 326 Gene3D G3DSA:3.40.50.720 125 270 1.3E-100 T 14-10-2018 D521_1547 92c7b4c6e8e0eb80cc28673aefbff999 326 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 89 3.9E-10 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 D521_1547 92c7b4c6e8e0eb80cc28673aefbff999 326 SUPERFAMILY SSF51735 113 266 1.12E-43 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0182 3e5c196053d43e61bd93d8379a822257 138 PRINTS PR00502 NUDIX hydrolase family signature 52 67 1.1E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 D521_0182 3e5c196053d43e61bd93d8379a822257 138 PRINTS PR00502 NUDIX hydrolase family signature 38 52 1.1E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 D521_0182 3e5c196053d43e61bd93d8379a822257 138 SUPERFAMILY SSF55811 5 116 1.76E-31 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 D521_0182 3e5c196053d43e61bd93d8379a822257 138 ProSitePatterns PS00893 Nudix box signature. 43 64 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 D521_0182 3e5c196053d43e61bd93d8379a822257 138 Gene3D G3DSA:3.90.79.10 8 135 2.0E-30 T 14-10-2018 D521_0182 3e5c196053d43e61bd93d8379a822257 138 Pfam PF00293 NUDIX domain 12 83 1.2E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 D521_0807 70e9e3dc1959883f0e7fa92d26188c3e 269 SUPERFAMILY SSF56300 1 242 1.65E-34 T 14-10-2018 D521_0807 70e9e3dc1959883f0e7fa92d26188c3e 269 Gene3D G3DSA:3.60.21.10 4 249 4.1E-19 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like D521_0807 70e9e3dc1959883f0e7fa92d26188c3e 269 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 7 220 7.0E-13 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 D521_0813 dd6f62729720d96a47079ed28eb38668 698 Pfam PF07715 TonB-dependent Receptor Plug Domain 47 149 7.8E-14 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain D521_0813 dd6f62729720d96a47079ed28eb38668 698 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 681 698 - T 14-10-2018 IPR010917 TonB-dependent receptor, conserved site D521_0813 dd6f62729720d96a47079ed28eb38668 698 Pfam PF00593 TonB dependent receptor 204 695 5.5E-32 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel D521_0813 dd6f62729720d96a47079ed28eb38668 698 Gene3D G3DSA:2.170.130.10 37 158 2.3E-22 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily D521_0813 dd6f62729720d96a47079ed28eb38668 698 Gene3D G3DSA:2.40.170.20 164 698 4.3E-45 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily D521_0813 dd6f62729720d96a47079ed28eb38668 698 SUPERFAMILY SSF56935 36 698 6.59E-69 T 14-10-2018 D521_0022 fe4be081906a68f9d82dccb002237a5e 466 Gene3D G3DSA:3.40.50.300 82 350 9.4E-112 T 14-10-2018 D521_0022 fe4be081906a68f9d82dccb002237a5e 466 SUPERFAMILY SSF47917 351 465 7.06E-55 T 14-10-2018 D521_0022 fe4be081906a68f9d82dccb002237a5e 466 Gene3D G3DSA:1.10.1140.10 351 466 5.2E-60 T 14-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0022 fe4be081906a68f9d82dccb002237a5e 466 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 466 1.4E-250 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 D521_0022 fe4be081906a68f9d82dccb002237a5e 466 SUPERFAMILY SSF50615 1 81 1.07E-24 T 14-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0022 fe4be081906a68f9d82dccb002237a5e 466 Gene3D G3DSA:2.40.10.170 1 81 6.2E-28 T 14-10-2018 D521_0022 fe4be081906a68f9d82dccb002237a5e 466 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 339 348 - T 14-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0022 fe4be081906a68f9d82dccb002237a5e 466 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 136 348 9.5E-64 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0022 fe4be081906a68f9d82dccb002237a5e 466 SMART SM00382 148 333 0.0016 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0022 fe4be081906a68f9d82dccb002237a5e 466 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 466 56.704 T 14-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 D521_0022 fe4be081906a68f9d82dccb002237a5e 466 SUPERFAMILY SSF52540 83 353 5.87E-89 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0022 fe4be081906a68f9d82dccb002237a5e 466 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 79 2.5E-19 T 14-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0626 a083ba90a318391edeb29d45d05244d8 304 SUPERFAMILY SSF55120 87 292 9.92E-44 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0626 a083ba90a318391edeb29d45d05244d8 304 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 132 146 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0626 a083ba90a318391edeb29d45d05244d8 304 Pfam PF00849 RNA pseudouridylate synthase 93 242 2.5E-19 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0626 a083ba90a318391edeb29d45d05244d8 304 Gene3D G3DSA:3.30.2350.10 78 295 2.0E-35 T 14-10-2018 D521_0400 4d650d7e11ba9602b201c72a711a4a0c 184 SUPERFAMILY SSF47616 67 183 1.3E-15 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily D521_0400 4d650d7e11ba9602b201c72a711a4a0c 184 Gene3D G3DSA:1.20.1050.10 59 167 2.5E-8 T 14-10-2018 D521_0400 4d650d7e11ba9602b201c72a711a4a0c 184 SUPERFAMILY SSF52833 1 58 3.86E-10 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0400 4d650d7e11ba9602b201c72a711a4a0c 184 Pfam PF13410 Glutathione S-transferase, C-terminal domain 108 163 1.0E-7 T 14-10-2018 D521_0400 4d650d7e11ba9602b201c72a711a4a0c 184 Gene3D G3DSA:3.40.30.10 1 57 6.0E-11 T 14-10-2018 D521_0400 4d650d7e11ba9602b201c72a711a4a0c 184 Pfam PF13417 Glutathione S-transferase, N-terminal domain 1 57 1.0E-8 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 D521_2018 58dba6dc2b92a6e73f17e2aabb716888 299 SUPERFAMILY SSF56349 90 292 5.59E-44 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_2018 58dba6dc2b92a6e73f17e2aabb716888 299 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 2 58 5.0E-8 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 D521_2018 58dba6dc2b92a6e73f17e2aabb716888 299 Gene3D G3DSA:1.10.443.10 93 288 6.8E-50 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 D521_2018 58dba6dc2b92a6e73f17e2aabb716888 299 Gene3D G3DSA:1.10.150.130 1 69 2.9E-8 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal D521_2018 58dba6dc2b92a6e73f17e2aabb716888 299 Pfam PF00589 Phage integrase family 110 280 6.5E-37 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 D521_2018 58dba6dc2b92a6e73f17e2aabb716888 299 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 2 294 47.915 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD D521_2018 58dba6dc2b92a6e73f17e2aabb716888 299 SUPERFAMILY SSF47823 2 64 2.35E-7 T 14-10-2018 D521_1048 912f92a597548d731d4486236a58c289 253 SUPERFAMILY SSF88713 30 252 1.75E-38 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 D521_1048 912f92a597548d731d4486236a58c289 253 Gene3D G3DSA:3.20.20.370 16 253 4.4E-37 T 14-10-2018 D521_1048 912f92a597548d731d4486236a58c289 253 Pfam PF01522 Polysaccharide deacetylase 28 178 7.3E-20 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 Hamap MF_01201 Alanine racemase. 10 374 31.678 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 SUPERFAMILY SSF50621 239 372 6.98E-43 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 Gene3D G3DSA:3.20.20.10 19 226 3.1E-108 T 14-10-2018 IPR029066 PLP-binding barrel D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 Pfam PF01168 Alanine racemase, N-terminal domain 17 228 1.8E-61 T 14-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 SUPERFAMILY SSF51419 17 241 2.36E-56 T 14-10-2018 IPR029066 PLP-binding barrel D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 Gene3D G3DSA:2.40.37.10 17 369 3.1E-108 T 14-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 Pfam PF00842 Alanine racemase, C-terminal domain 243 371 3.9E-42 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 SMART SM01005 243 374 1.8E-63 T 14-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 PRINTS PR00992 Alanine racemase signature 201 228 5.5E-55 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 PRINTS PR00992 Alanine racemase signature 259 274 5.5E-55 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 PRINTS PR00992 Alanine racemase signature 276 291 5.5E-55 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 PRINTS PR00992 Alanine racemase signature 356 369 5.5E-55 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 PRINTS PR00992 Alanine racemase signature 35 51 5.5E-55 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 PRINTS PR00992 Alanine racemase signature 131 143 5.5E-55 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 PRINTS PR00992 Alanine racemase signature 163 174 5.5E-55 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 PRINTS PR00992 Alanine racemase signature 69 87 5.5E-55 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_0915 f5bb46ff50af73cd034e339e3c7130c0 374 TIGRFAM TIGR00492 alr: alanine racemase 12 371 1.9E-105 T 14-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 D521_2000 0616605ce86ae850a88aa2ee5cae30fb 302 SUPERFAMILY SSF51735 3 270 6.51E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_2000 0616605ce86ae850a88aa2ee5cae30fb 302 Gene3D G3DSA:3.40.50.720 2 236 4.0E-43 T 14-10-2018 D521_2000 0616605ce86ae850a88aa2ee5cae30fb 302 Pfam PF13460 NAD(P)H-binding 9 205 1.2E-17 T 14-10-2018 IPR016040 NAD(P)-binding domain D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 Gene3D G3DSA:1.10.10.650 2 109 2.9E-39 T 14-10-2018 IPR023319 Tex-like protein, HTH domain superfamily D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 Pfam PF12836 Helix-hairpin-helix motif 503 567 3.9E-26 T 14-10-2018 D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 SUPERFAMILY SSF53098 333 481 5.01E-49 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 SUPERFAMILY SSF158832 2 332 1.31E-111 T 14-10-2018 D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 SUPERFAMILY SSF47781 573 644 3.11E-21 T 14-10-2018 IPR010994 RuvA domain 2-like D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 Pfam PF00575 S1 RNA binding domain 661 732 5.6E-21 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 SMART SM00732 337 436 1.9E-36 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 SMART SM00316 661 732 9.9E-24 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 Gene3D G3DSA:1.10.150.310 511 642 7.8E-50 T 14-10-2018 D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 Gene3D G3DSA:3.30.420.140 336 463 4.3E-151 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 Gene3D G3DSA:2.40.50.140 643 736 3.0E-27 T 14-10-2018 D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 Pfam PF09371 Tex-like protein N-terminal domain 9 201 3.3E-66 T 14-10-2018 IPR018974 Tex-like protein, N-terminal D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 Pfam PF16921 Tex protein YqgF-like domain 337 463 5.9E-52 T 14-10-2018 IPR032639 Tex protein, YqgF-like domain D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 SUPERFAMILY SSF47781 482 569 3.67E-26 T 14-10-2018 IPR010994 RuvA domain 2-like D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 Gene3D G3DSA:1.10.3500.10 112 510 4.3E-151 T 14-10-2018 IPR023323 Tex-like domain superfamily D521_0615 5d33ed60964be7b3e901bf40d19f3355 786 SUPERFAMILY SSF50249 649 738 1.72E-24 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1262 29fa312bf6c54bdcc3cb05853f818f07 278 SUPERFAMILY SSF55920 8 255 2.09E-86 T 14-10-2018 IPR036005 Creatinase/aminopeptidase-like D521_1262 29fa312bf6c54bdcc3cb05853f818f07 278 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 6 254 1.1E-94 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 D521_1262 29fa312bf6c54bdcc3cb05853f818f07 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 167 179 7.0E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 D521_1262 29fa312bf6c54bdcc3cb05853f818f07 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 96 112 7.0E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 D521_1262 29fa312bf6c54bdcc3cb05853f818f07 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 74 87 7.0E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 D521_1262 29fa312bf6c54bdcc3cb05853f818f07 278 PRINTS PR00599 Methionine aminopeptidase-1 signature 198 210 7.0E-17 T 14-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 D521_1262 29fa312bf6c54bdcc3cb05853f818f07 278 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 173 191 - T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 D521_1262 29fa312bf6c54bdcc3cb05853f818f07 278 Pfam PF00557 Metallopeptidase family M24 13 247 8.5E-53 T 14-10-2018 IPR000994 Peptidase M24 D521_1262 29fa312bf6c54bdcc3cb05853f818f07 278 Hamap MF_01974 Methionine aminopeptidase [map]. 3 256 40.232 T 14-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 D521_1262 29fa312bf6c54bdcc3cb05853f818f07 278 Gene3D G3DSA:3.90.230.10 4 262 2.3E-106 T 14-10-2018 D521_0819 571c991541acab173f7fd50456efbdc2 297 SUPERFAMILY SSF53474 11 296 4.21E-67 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0819 571c991541acab173f7fd50456efbdc2 297 PRINTS PR00412 Epoxide hydrolase signature 39 57 5.4E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_0819 571c991541acab173f7fd50456efbdc2 297 PRINTS PR00412 Epoxide hydrolase signature 273 295 5.4E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_0819 571c991541acab173f7fd50456efbdc2 297 PRINTS PR00412 Epoxide hydrolase signature 121 134 5.4E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_0819 571c991541acab173f7fd50456efbdc2 297 PRINTS PR00412 Epoxide hydrolase signature 107 120 5.4E-6 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_0819 571c991541acab173f7fd50456efbdc2 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 1.5E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_0819 571c991541acab173f7fd50456efbdc2 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 58 73 1.5E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_0819 571c991541acab173f7fd50456efbdc2 297 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 1.5E-6 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_0819 571c991541acab173f7fd50456efbdc2 297 Gene3D G3DSA:3.40.50.1820 2 297 1.4E-76 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0819 571c991541acab173f7fd50456efbdc2 297 Pfam PF00561 alpha/beta hydrolase fold 33 158 2.7E-26 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1990 eabd9340080bd010637be3ad96e83900 185 Gene3D G3DSA:3.40.50.360 1 185 1.7E-60 T 14-10-2018 IPR029039 Flavoprotein-like superfamily D521_1990 eabd9340080bd010637be3ad96e83900 185 Pfam PF03358 NADPH-dependent FMN reductase 44 118 1.5E-9 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 D521_1990 eabd9340080bd010637be3ad96e83900 185 SUPERFAMILY SSF52218 1 180 7.34E-45 T 14-10-2018 IPR029039 Flavoprotein-like superfamily D521_1990 eabd9340080bd010637be3ad96e83900 185 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 14-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 D521_0565 aa51766a91581f7e89f210054bd5918d 605 Pfam PF05170 AsmA family 201 492 4.1E-12 T 14-10-2018 IPR007844 AsmA D521_0565 aa51766a91581f7e89f210054bd5918d 605 Pfam PF05170 AsmA family 1 173 1.0E-24 T 14-10-2018 IPR007844 AsmA D521_0510 7c8c9bba272153a7769c2e28f9f0907f 310 SUPERFAMILY SSF50486 204 294 3.45E-17 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 D521_0510 7c8c9bba272153a7769c2e28f9f0907f 310 Pfam PF02911 Formyl transferase, C-terminal domain 206 293 9.4E-14 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_0510 7c8c9bba272153a7769c2e28f9f0907f 310 Pfam PF00551 Formyl transferase 1 161 8.8E-28 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_0510 7c8c9bba272153a7769c2e28f9f0907f 310 SUPERFAMILY SSF53328 1 197 1.1E-45 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_0510 7c8c9bba272153a7769c2e28f9f0907f 310 Gene3D G3DSA:3.40.50.12230 1 308 1.5E-72 T 14-10-2018 D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 526 4.8E-217 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 SUPERFAMILY SSF53927 215 526 1.0E-123 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 SMART SM00798 134 458 3.3E-197 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 Pfam PF02142 MGS-like domain 14 128 9.7E-30 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 456 8.2E-118 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 526 44.006 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 Gene3D G3DSA:3.40.50.1380 1 196 8.7E-86 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 Gene3D G3DSA:3.40.140.20 212 371 9.9E-57 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 Gene3D G3DSA:3.40.140.20 390 526 1.1E-54 T 14-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 PIRSF PIRSF000414 1 526 7.3E-213 T 14-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 SMART SM00851 14 129 3.2E-58 T 14-10-2018 IPR011607 Methylglyoxal synthase-like domain D521_1871 3ea1bb2ad79dc5b49c35c45bc1549b05 526 SUPERFAMILY SSF52335 2 193 1.7E-69 T 14-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 1.2E-71 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 Gene3D G3DSA:3.90.930.12 83 177 1.7E-38 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 PIRSF PIRSF002162 1 177 3.7E-48 T 14-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 36.041 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 14-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 SUPERFAMILY SSF56053 1 82 6.56E-24 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 Gene3D G3DSA:3.90.930.12 1 82 9.0E-27 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 SUPERFAMILY SSF56053 83 177 2.62E-34 T 14-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 PRINTS PR00059 Ribosomal protein L6 signature 71 96 2.6E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 PRINTS PR00059 Ribosomal protein L6 signature 141 162 2.6E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 PRINTS PR00059 Ribosomal protein L6 signature 99 115 2.6E-32 T 14-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 Pfam PF00347 Ribosomal protein L6 11 82 2.5E-15 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0067 4dec94b983f0b7e7e6b09d6f81931f49 177 Pfam PF00347 Ribosomal protein L6 90 164 9.8E-18 T 14-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0763 ac3db599628faa20cdd8873c5d8aa81d 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 7 104 3.6E-26 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 D521_0763 ac3db599628faa20cdd8873c5d8aa81d 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 209 1.7E-14 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 D521_0763 ac3db599628faa20cdd8873c5d8aa81d 217 Gene3D G3DSA:1.10.3720.10 2 211 1.1E-44 T 14-10-2018 IPR035906 MetI-like superfamily D521_0763 ac3db599628faa20cdd8873c5d8aa81d 217 SUPERFAMILY SSF161098 10 195 8.37E-38 T 14-10-2018 IPR035906 MetI-like superfamily D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 SMART SM00382 182 321 1.5E-26 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 ProSitePatterns PS00674 AAA-protein family signature. 289 307 - T 14-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 607 621 3.6E-6 T 14-10-2018 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 190 209 3.6E-6 T 14-10-2018 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 SUPERFAMILY SSF52540 146 389 4.69E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 186 318 9.2E-46 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 101 587 1.5E-233 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 Pfam PF06480 FtsH Extracellular 7 74 1.6E-8 T 14-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 Gene3D G3DSA:3.40.50.300 134 320 5.9E-70 T 14-10-2018 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 Pfam PF01434 Peptidase family M41 380 586 2.1E-77 T 14-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 Gene3D G3DSA:1.10.8.60 321 394 4.7E-30 T 14-10-2018 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 Gene3D G3DSA:1.20.58.760 395 591 4.7E-71 T 14-10-2018 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 Gene3D G3DSA:2.40.50.920 24 99 1.7E-9 T 14-10-2018 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 SUPERFAMILY SSF140990 400 597 2.75E-71 T 14-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 D521_0784 592b001b8ff09c7c55a81d9c2bf649fb 621 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 1 593 36.809 T 14-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 D521_1612 3ed9e7e1f23eafc8f718c474eddf2d6b 218 SUPERFAMILY SSF52833 4 217 1.21E-40 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1612 3ed9e7e1f23eafc8f718c474eddf2d6b 218 Gene3D G3DSA:3.40.30.10 1 215 5.2E-62 T 14-10-2018 D521_1612 3ed9e7e1f23eafc8f718c474eddf2d6b 218 Pfam PF01323 DSBA-like thioredoxin domain 6 211 1.8E-29 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 D521_1322 b0ec57a5b5ae90d80b5c6822449fa6f8 349 Gene3D G3DSA:3.30.160.20 210 305 1.6E-96 T 14-10-2018 D521_1322 b0ec57a5b5ae90d80b5c6822449fa6f8 349 Pfam PF03462 PCRF domain 16 204 4.9E-54 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 D521_1322 b0ec57a5b5ae90d80b5c6822449fa6f8 349 SMART SM00937 69 179 1.4E-54 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 D521_1322 b0ec57a5b5ae90d80b5c6822449fa6f8 349 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 229 245 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 D521_1322 b0ec57a5b5ae90d80b5c6822449fa6f8 349 Pfam PF00472 RF-1 domain 213 321 3.9E-41 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 D521_1322 b0ec57a5b5ae90d80b5c6822449fa6f8 349 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 349 37.189 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 D521_1322 b0ec57a5b5ae90d80b5c6822449fa6f8 349 SUPERFAMILY SSF75620 16 346 9.81E-131 T 14-10-2018 D521_1322 b0ec57a5b5ae90d80b5c6822449fa6f8 349 Gene3D G3DSA:1.20.58.410 2 100 3.1E-22 T 14-10-2018 D521_1322 b0ec57a5b5ae90d80b5c6822449fa6f8 349 Gene3D G3DSA:3.30.70.1660 114 342 1.6E-96 T 14-10-2018 D521_1322 b0ec57a5b5ae90d80b5c6822449fa6f8 349 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 3 347 3.0E-153 T 14-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 D521_0051 b9c0b3790ca2940852c9ce403d287363 103 SMART SM01403 7 101 1.2E-54 T 14-10-2018 IPR027486 Ribosomal protein S10 domain D521_0051 b9c0b3790ca2940852c9ce403d287363 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 14-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0051 b9c0b3790ca2940852c9ce403d287363 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 3.0E-34 T 14-10-2018 IPR027486 Ribosomal protein S10 domain D521_0051 b9c0b3790ca2940852c9ce403d287363 103 SUPERFAMILY SSF54999 5 102 1.44E-36 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily D521_0051 b9c0b3790ca2940852c9ce403d287363 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.2E-45 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0051 b9c0b3790ca2940852c9ce403d287363 103 Gene3D G3DSA:3.30.70.600 1 102 6.2E-36 T 14-10-2018 IPR036838 Ribosomal protein S10 domain superfamily D521_0051 b9c0b3790ca2940852c9ce403d287363 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 1.3E-16 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0051 b9c0b3790ca2940852c9ce403d287363 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 1.3E-16 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0051 b9c0b3790ca2940852c9ce403d287363 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 1.3E-16 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0051 b9c0b3790ca2940852c9ce403d287363 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.026 T 14-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_1690 04f80351044e891716dbe6dd3baa7659 70 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 20.383 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1690 04f80351044e891716dbe6dd3baa7659 70 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 42 6.0E-8 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1690 04f80351044e891716dbe6dd3baa7659 70 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 2.9E-24 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1690 04f80351044e891716dbe6dd3baa7659 70 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 14-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1690 04f80351044e891716dbe6dd3baa7659 70 Pfam PF01165 Ribosomal protein S21 3 57 1.4E-20 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1690 04f80351044e891716dbe6dd3baa7659 70 Gene3D G3DSA:1.20.5.1150 16 54 4.8E-19 T 14-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1690 04f80351044e891716dbe6dd3baa7659 70 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 1.4E-14 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1690 04f80351044e891716dbe6dd3baa7659 70 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 1.4E-14 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1690 04f80351044e891716dbe6dd3baa7659 70 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 1.4E-14 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1690 04f80351044e891716dbe6dd3baa7659 70 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 1.4E-14 T 14-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_2002 1b2b588b8f5de5ae42af527741d647ef 195 Gene3D G3DSA:3.40.50.10420 2 194 4.6E-33 T 14-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily D521_2002 1b2b588b8f5de5ae42af527741d647ef 195 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 188 3.7E-28 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase D521_2002 1b2b588b8f5de5ae42af527741d647ef 195 PIRSF PIRSF006806 1 190 3.6E-24 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase D521_2002 1b2b588b8f5de5ae42af527741d647ef 195 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 15 188 3.3E-19 T 14-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase D521_2002 1b2b588b8f5de5ae42af527741d647ef 195 SUPERFAMILY SSF100950 25 193 4.46E-35 T 14-10-2018 IPR037171 NagB/RpiA transferase-like D521_0751 219198667952e85e595efc890939741c 432 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 337 419 3.3E-30 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0751 219198667952e85e595efc890939741c 432 Gene3D G3DSA:3.40.50.11540 58 235 4.4E-73 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0751 219198667952e85e595efc890939741c 432 SUPERFAMILY SSF142019 19 245 4.18E-81 T 14-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0751 219198667952e85e595efc890939741c 432 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 19 420 9.7E-188 T 14-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0751 219198667952e85e595efc890939741c 432 SUPERFAMILY SSF142984 246 329 1.26E-23 T 14-10-2018 D521_0751 219198667952e85e595efc890939741c 432 SUPERFAMILY SSF140490 331 426 1.1E-36 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0751 219198667952e85e595efc890939741c 432 Pfam PF10531 SLBB domain 248 296 7.2E-12 T 14-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0751 219198667952e85e595efc890939741c 432 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 54 224 4.3E-45 T 14-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0751 219198667952e85e595efc890939741c 432 Gene3D G3DSA:1.20.1440.230 332 430 2.1E-33 T 14-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0751 219198667952e85e595efc890939741c 432 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 347 358 - T 14-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0751 219198667952e85e595efc890939741c 432 Gene3D G3DSA:3.10.20.600 237 331 4.5E-33 T 14-10-2018 D521_0751 219198667952e85e595efc890939741c 432 SMART SM00928 334 379 3.9E-26 T 14-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0141 15568fa2571eed02c810f21f658e3a1d 238 ProSitePatterns PS00194 Thioredoxin family active site. 120 138 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 D521_0141 15568fa2571eed02c810f21f658e3a1d 238 SUPERFAMILY SSF52833 94 235 7.35E-35 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0141 15568fa2571eed02c810f21f658e3a1d 238 Pfam PF10411 Disulfide bond isomerase protein N-terminus 35 83 8.7E-19 T 14-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal D521_0141 15568fa2571eed02c810f21f658e3a1d 238 Gene3D G3DSA:3.10.450.70 22 88 3.8E-12 T 14-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 D521_0141 15568fa2571eed02c810f21f658e3a1d 238 Pfam PF13098 Thioredoxin-like domain 113 232 4.0E-28 T 14-10-2018 IPR012336 Thioredoxin-like fold D521_0141 15568fa2571eed02c810f21f658e3a1d 238 SUPERFAMILY SSF54423 26 85 1.73E-12 T 14-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 D521_0141 15568fa2571eed02c810f21f658e3a1d 238 Gene3D G3DSA:3.40.30.10 104 236 1.8E-34 T 14-10-2018 D521_1908 cebe135980a74994a1470b4831558bee 107 Gene3D G3DSA:3.30.160.100 1 107 7.0E-31 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like D521_1908 cebe135980a74994a1470b4831558bee 107 SUPERFAMILY SSF69754 1 105 5.49E-30 T 14-10-2018 IPR036567 Ribosome hibernation promotion factor-like D521_1908 cebe135980a74994a1470b4831558bee 107 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 4 97 3.9E-22 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 D521_1908 cebe135980a74994a1470b4831558bee 107 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 104 2.8E-28 T 14-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 Gene3D G3DSA:3.10.50.40 203 432 1.3E-60 T 14-10-2018 D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 SUPERFAMILY SSF54534 331 431 1.24E-30 T 14-10-2018 D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 Pfam PF00639 PPIC-type PPIASE domain 336 426 1.9E-24 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 Gene3D G3DSA:1.10.4030.30 41 189 2.9E-39 T 14-10-2018 D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 Gene3D G3DSA:3.10.50.40 330 431 1.3E-60 T 14-10-2018 D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 Pfam PF13616 PPIC-type PPIASE domain 196 302 2.8E-11 T 14-10-2018 D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 SUPERFAMILY SSF109998 43 230 9.42E-37 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 368 388 - T 14-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 SUPERFAMILY SSF54534 199 303 3.07E-13 T 14-10-2018 D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 Hamap MF_01183 Chaperone SurA [surA]. 11 474 28.697 T 14-10-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0043165|GO:0050821|GO:0051082|GO:0060274 D521_1863 97a1ba1390a7a1cd8bbc7307fbd8b580 482 Pfam PF09312 SurA N-terminal domain 43 156 5.4E-31 T 14-10-2018 IPR015391 SurA N-terminal D521_1351 194a56e175250be581c6a4c350259153 419 Gene3D G3DSA:3.40.640.10 33 277 2.4E-158 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_1351 194a56e175250be581c6a4c350259153 419 TIGRFAM TIGR02006 IscS: cysteine desulfurase IscS 20 419 5.0E-223 T 14-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 D521_1351 194a56e175250be581c6a4c350259153 419 Gene3D G3DSA:3.90.1150.10 22 390 2.4E-158 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_1351 194a56e175250be581c6a4c350259153 419 PIRSF PIRSF005572 19 399 2.1E-128 T 14-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 D521_1351 194a56e175250be581c6a4c350259153 419 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 212 231 - T 14-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site D521_1351 194a56e175250be581c6a4c350259153 419 Pfam PF00266 Aminotransferase class-V 22 382 1.9E-83 T 14-10-2018 IPR000192 Aminotransferase class V domain D521_1351 194a56e175250be581c6a4c350259153 419 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 18 410 52.888 T 14-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 D521_1351 194a56e175250be581c6a4c350259153 419 SUPERFAMILY SSF53383 22 405 8.16E-109 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0191 d4a96424cdd6dafe25daf32486a3b7b7 471 Pfam PF00474 Sodium:solute symporter family 32 427 1.9E-33 T 14-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 D521_0191 d4a96424cdd6dafe25daf32486a3b7b7 471 Gene3D G3DSA:1.20.1730.10 18 467 3.4E-66 T 14-10-2018 IPR038377 Sodium/glucose symporter superfamily D521_1228 6f3e81595588835b5bf007f04998316f 150 Pfam PF01668 SmpB protein 3 144 2.3E-55 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 D521_1228 6f3e81595588835b5bf007f04998316f 150 Gene3D G3DSA:2.40.280.10 1 124 1.9E-46 T 14-10-2018 IPR023620 Small protein B D521_1228 6f3e81595588835b5bf007f04998316f 150 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 3 127 2.0E-55 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 D521_1228 6f3e81595588835b5bf007f04998316f 150 SUPERFAMILY SSF74982 3 127 9.42E-49 T 14-10-2018 IPR023620 Small protein B D521_1228 6f3e81595588835b5bf007f04998316f 150 ProSitePatterns PS01317 SsrA-binding protein. 21 33 - T 14-10-2018 IPR020081 SsrA-binding protein, conserved site D521_1228 6f3e81595588835b5bf007f04998316f 150 TIGRFAM TIGR00086 smpB: SsrA-binding protein 3 142 7.1E-52 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 D521_1228 6f3e81595588835b5bf007f04998316f 150 Hamap MF_00023 SsrA-binding protein [smpB]. 1 150 66.676 T 14-10-2018 IPR000037 SsrA-binding protein GO:0003723 D521_1742 3bdb84c88bfb33085f90af0f1f09de31 334 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 18 326 28.631 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 D521_1742 3bdb84c88bfb33085f90af0f1f09de31 334 SUPERFAMILY SSF52540 18 167 4.53E-17 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1742 3bdb84c88bfb33085f90af0f1f09de31 334 Pfam PF01715 IPP transferase 57 306 2.5E-78 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 D521_1742 3bdb84c88bfb33085f90af0f1f09de31 334 Gene3D G3DSA:1.10.20.140 130 208 4.1E-89 T 14-10-2018 D521_1742 3bdb84c88bfb33085f90af0f1f09de31 334 Pfam PF01695 IstB-like ATP binding protein 19 53 1.9E-5 T 14-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 D521_1742 3bdb84c88bfb33085f90af0f1f09de31 334 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 19 314 2.7E-84 T 14-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 D521_1742 3bdb84c88bfb33085f90af0f1f09de31 334 Gene3D G3DSA:3.40.50.300 22 307 4.1E-89 T 14-10-2018 D521_0348 8e8a8caef31662b0efb00fbdc2da5770 547 Pfam PF05199 GMC oxidoreductase 402 540 1.5E-40 T 14-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 D521_0348 8e8a8caef31662b0efb00fbdc2da5770 547 PIRSF PIRSF000137 2 547 9.8E-146 T 14-10-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 D521_0348 8e8a8caef31662b0efb00fbdc2da5770 547 SUPERFAMILY SSF54373 305 488 2.06E-58 T 14-10-2018 D521_0348 8e8a8caef31662b0efb00fbdc2da5770 547 Gene3D G3DSA:3.30.560.10 48 483 1.3E-169 T 14-10-2018 D521_0348 8e8a8caef31662b0efb00fbdc2da5770 547 Pfam PF00732 GMC oxidoreductase 10 310 1.4E-78 T 14-10-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 D521_0348 8e8a8caef31662b0efb00fbdc2da5770 547 Gene3D G3DSA:3.50.50.60 10 543 1.3E-169 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0348 8e8a8caef31662b0efb00fbdc2da5770 547 SUPERFAMILY SSF51905 6 545 5.92E-83 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0698 a2b22bfc0539f8a11259dc07319ae5db 219 SUPERFAMILY SSF52096 47 150 4.47E-10 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_0698 a2b22bfc0539f8a11259dc07319ae5db 219 Gene3D G3DSA:3.90.226.10 47 216 1.8E-13 T 14-10-2018 D521_0698 a2b22bfc0539f8a11259dc07319ae5db 219 Pfam PF00574 Clp protease 52 185 2.0E-5 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA D521_0549 4738412068543b6c9a3249d4c5c4ca8b 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 D521_0549 4738412068543b6c9a3249d4c5c4ca8b 178 Gene3D G3DSA:3.90.80.10 1 175 1.6E-70 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 D521_0549 4738412068543b6c9a3249d4c5c4ca8b 178 SUPERFAMILY SSF50324 3 175 5.63E-67 T 14-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 D521_0549 4738412068543b6c9a3249d4c5c4ca8b 178 Pfam PF00719 Inorganic pyrophosphatase 18 173 9.5E-53 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 D521_0549 4738412068543b6c9a3249d4c5c4ca8b 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 35.307 T 14-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 D521_0256 f57cb3c84018273b034f407554a8abd9 343 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 86 330 2.9E-39 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 D521_0256 f57cb3c84018273b034f407554a8abd9 343 Gene3D G3DSA:3.40.50.2000 192 337 3.2E-31 T 14-10-2018 D521_0256 f57cb3c84018273b034f407554a8abd9 343 SUPERFAMILY SSF53756 6 341 3.3E-59 T 14-10-2018 D521_0256 f57cb3c84018273b034f407554a8abd9 343 TIGRFAM TIGR02193 heptsyl_trn_I: lipopolysaccharide heptosyltransferase I 6 336 9.6E-89 T 14-10-2018 IPR011908 Lipopolysaccharide heptosyltransferase I GO:0008920|GO:0009244 D521_0256 f57cb3c84018273b034f407554a8abd9 343 Gene3D G3DSA:3.40.50.2000 6 177 8.6E-48 T 14-10-2018 D521_1699 6136c78a3a7b4dab579830365fddc9d2 298 Pfam PF01738 Dienelactone hydrolase family 67 294 3.7E-58 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 D521_1699 6136c78a3a7b4dab579830365fddc9d2 298 SUPERFAMILY SSF53474 58 294 7.66E-42 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1699 6136c78a3a7b4dab579830365fddc9d2 298 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 15 42 1.9E-4 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal D521_1699 6136c78a3a7b4dab579830365fddc9d2 298 Gene3D G3DSA:3.40.50.1820 52 294 1.1E-59 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1481 50748ae64233c11543e2aff3bbf707fc 376 Gene3D G3DSA:3.90.1150.10 26 367 4.6E-115 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_1481 50748ae64233c11543e2aff3bbf707fc 376 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 373 60.601 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 D521_1481 50748ae64233c11543e2aff3bbf707fc 376 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 10 372 8.0E-102 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 D521_1481 50748ae64233c11543e2aff3bbf707fc 376 Gene3D G3DSA:3.40.640.10 50 278 4.6E-115 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_1481 50748ae64233c11543e2aff3bbf707fc 376 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 14-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 D521_1481 50748ae64233c11543e2aff3bbf707fc 376 Pfam PF00155 Aminotransferase class I and II 37 362 1.6E-52 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 D521_1481 50748ae64233c11543e2aff3bbf707fc 376 SUPERFAMILY SSF53383 17 373 3.94E-82 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_1136 b1cbd98bd5715de71a642057bdc7eaec 293 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 161 1.6E-50 T 14-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 D521_1136 b1cbd98bd5715de71a642057bdc7eaec 293 Gene3D G3DSA:1.10.1040.10 163 293 1.9E-43 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 D521_1136 b1cbd98bd5715de71a642057bdc7eaec 293 PIRSF PIRSF000103 1 293 4.6E-79 T 14-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 D521_1136 b1cbd98bd5715de71a642057bdc7eaec 293 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 289 3.8E-33 T 14-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 D521_1136 b1cbd98bd5715de71a642057bdc7eaec 293 SUPERFAMILY SSF51735 1 161 7.09E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1136 b1cbd98bd5715de71a642057bdc7eaec 293 Gene3D G3DSA:3.40.50.720 1 162 2.3E-57 T 14-10-2018 D521_1136 b1cbd98bd5715de71a642057bdc7eaec 293 SUPERFAMILY SSF48179 162 291 9.75E-39 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_1136 b1cbd98bd5715de71a642057bdc7eaec 293 TIGRFAM TIGR01692 HIBADH: 3-hydroxyisobutyrate dehydrogenase 5 290 7.3E-122 T 14-10-2018 IPR011548 3-hydroxyisobutyrate dehydrogenase GO:0008442|GO:0051287|GO:0055114 KEGG: 00280+1.1.1.31|Reactome: R-HSA-70895 D521_1136 b1cbd98bd5715de71a642057bdc7eaec 293 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 14-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 D521_0206 459678292c91560b145d440354730e59 988 PRINTS PR01183 Ribonucleotide reductase large chain signature 707 730 1.8E-44 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 PRINTS PR01183 Ribonucleotide reductase large chain signature 599 610 1.8E-44 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 PRINTS PR01183 Ribonucleotide reductase large chain signature 679 701 1.8E-44 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 PRINTS PR01183 Ribonucleotide reductase large chain signature 464 483 1.8E-44 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 PRINTS PR01183 Ribonucleotide reductase large chain signature 641 664 1.8E-44 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 PRINTS PR01183 Ribonucleotide reductase large chain signature 783 810 1.8E-44 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 312 384 1.1E-19 T 14-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 Gene3D G3DSA:3.20.70.20 242 939 2.9E-246 T 14-10-2018 D521_0206 459678292c91560b145d440354730e59 988 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 315 931 3.3E-212 T 14-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 SUPERFAMILY SSF51998 388 931 3.66E-179 T 14-10-2018 D521_0206 459678292c91560b145d440354730e59 988 Pfam PF02867 Ribonucleotide reductase, barrel domain 389 928 5.4E-185 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 SUPERFAMILY SSF48168 176 387 5.23E-59 T 14-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 Pfam PF03477 ATP cone domain 51 147 1.1E-18 T 14-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 D521_0206 459678292c91560b145d440354730e59 988 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 772 794 - T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_1213 0856eb82e0644f92be0e35199cac9d9c 631 Gene3D G3DSA:3.80.30.20 355 537 4.0E-12 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe D521_1213 0856eb82e0644f92be0e35199cac9d9c 631 Pfam PF04055 Radical SAM superfamily 360 521 2.0E-10 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 D521_1213 0856eb82e0644f92be0e35199cac9d9c 631 SUPERFAMILY SSF102114 335 525 9.81E-25 T 14-10-2018 D521_1213 0856eb82e0644f92be0e35199cac9d9c 631 SMART SM00729 357 570 1.6E-13 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 SUPERFAMILY SSF53633 1 238 1.26E-64 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 Pfam PF00696 Amino acid kinase family 5 217 1.2E-42 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 PIRSF PIRSF000726 47 404 1.1E-138 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 PIRSF PIRSF000726 1 50 5.5E-13 T 14-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 PRINTS PR00474 Glutamate 5-kinase family signature 21 35 3.9E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 PRINTS PR00474 Glutamate 5-kinase family signature 140 167 3.9E-5 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 Pfam PF01842 ACT domain 264 322 1.1E-9 T 14-10-2018 IPR002912 ACT domain D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 SUPERFAMILY SSF55021 328 402 7.2E-26 T 14-10-2018 D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 SUPERFAMILY SSF55021 245 324 8.51E-18 T 14-10-2018 D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 Gene3D G3DSA:3.30.70.260 251 401 1.2E-58 T 14-10-2018 D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 Gene3D G3DSA:3.30.70.260 258 336 1.2E-58 T 14-10-2018 D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 Pfam PF13840 ACT domain 337 397 1.6E-17 T 14-10-2018 IPR027795 CASTOR, ACT domain D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 Gene3D G3DSA:3.40.1160.10 1 250 4.2E-77 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily D521_0868 c4724a6eeacc0661b9b2502e88de6309 404 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 51 400 6.2E-113 T 14-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 D521_1361 595257c00140b0350e7fe55146c82e2c 346 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 156 1.6E-18 T 14-10-2018 IPR016188 PurM-like, N-terminal domain D521_1361 595257c00140b0350e7fe55146c82e2c 346 PIRSF PIRSF036407 1 345 3.2E-112 T 14-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 D521_1361 595257c00140b0350e7fe55146c82e2c 346 TIGRFAM TIGR00476 selD: selenide, water dikinase 6 315 1.0E-127 T 14-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 D521_1361 595257c00140b0350e7fe55146c82e2c 346 Gene3D G3DSA:3.90.650.10 163 345 7.9E-52 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily D521_1361 595257c00140b0350e7fe55146c82e2c 346 Pfam PF02769 AIR synthase related protein, C-terminal domain 170 345 6.0E-30 T 14-10-2018 IPR010918 PurM-like, C-terminal domain D521_1361 595257c00140b0350e7fe55146c82e2c 346 SUPERFAMILY SSF56042 163 344 1.44E-47 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily D521_1361 595257c00140b0350e7fe55146c82e2c 346 SUPERFAMILY SSF55326 6 160 2.39E-38 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily D521_1361 595257c00140b0350e7fe55146c82e2c 346 Hamap MF_00625 Selenide, water dikinase [selD]. 4 346 41.858 T 14-10-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 D521_1361 595257c00140b0350e7fe55146c82e2c 346 Gene3D G3DSA:3.30.1330.10 2 161 4.4E-45 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily D521_0610 8e5b176d527c06abef93aceee760e121 493 SMART SM00316 136 203 3.1E-10 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_0610 8e5b176d527c06abef93aceee760e121 493 Pfam PF14520 Helix-hairpin-helix domain 433 488 3.6E-7 T 14-10-2018 D521_0610 8e5b176d527c06abef93aceee760e121 493 Gene3D G3DSA:2.40.50.140 140 201 1.0E-19 T 14-10-2018 D521_0610 8e5b176d527c06abef93aceee760e121 493 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 413 28.596 T 14-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 D521_0610 8e5b176d527c06abef93aceee760e121 493 SUPERFAMILY SSF47794 430 492 1.57E-14 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 D521_0610 8e5b176d527c06abef93aceee760e121 493 SUPERFAMILY SSF54814 282 345 4.84E-15 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 D521_0610 8e5b176d527c06abef93aceee760e121 493 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 443 490 1.1E-13 T 14-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication D521_0610 8e5b176d527c06abef93aceee760e121 493 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 368 416 1.3E-19 T 14-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication D521_0610 8e5b176d527c06abef93aceee760e121 493 Gene3D G3DSA:3.30.300.20 281 349 5.8E-26 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta D521_0610 8e5b176d527c06abef93aceee760e121 493 Gene3D G3DSA:1.10.150.20 355 424 8.9E-28 T 14-10-2018 D521_0610 8e5b176d527c06abef93aceee760e121 493 Pfam PF08529 NusA N-terminal domain 5 128 2.9E-34 T 14-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 D521_0610 8e5b176d527c06abef93aceee760e121 493 Gene3D G3DSA:3.30.300.20 202 280 7.5E-27 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta D521_0610 8e5b176d527c06abef93aceee760e121 493 SUPERFAMILY SSF69705 1 130 9.42E-36 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 D521_0610 8e5b176d527c06abef93aceee760e121 493 SUPERFAMILY SSF50249 138 202 1.56E-16 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_0610 8e5b176d527c06abef93aceee760e121 493 Gene3D G3DSA:3.30.1480.10 1 133 6.3E-40 T 14-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 D521_0610 8e5b176d527c06abef93aceee760e121 493 Pfam PF13184 NusA-like KH domain 233 300 1.6E-22 T 14-10-2018 IPR025249 KH domain, NusA-like GO:0003723 D521_0610 8e5b176d527c06abef93aceee760e121 493 SUPERFAMILY SSF47794 357 419 2.35E-16 T 14-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 D521_0610 8e5b176d527c06abef93aceee760e121 493 Gene3D G3DSA:1.10.150.20 432 490 4.8E-21 T 14-10-2018 D521_0610 8e5b176d527c06abef93aceee760e121 493 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 6 344 2.2E-118 T 14-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 D521_0610 8e5b176d527c06abef93aceee760e121 493 Pfam PF00575 S1 RNA binding domain 140 199 1.6E-7 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_0610 8e5b176d527c06abef93aceee760e121 493 SUPERFAMILY SSF54814 203 281 8.5E-27 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 D521_1838 0623be306f4d5dfd0ed550cc44551ca6 556 Pfam PF00083 Sugar (and other) transporter 445 551 1.8E-6 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 D521_1838 0623be306f4d5dfd0ed550cc44551ca6 556 Pfam PF07690 Major Facilitator Superfamily 26 335 2.4E-26 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_1838 0623be306f4d5dfd0ed550cc44551ca6 556 SUPERFAMILY SSF103473 454 551 3.14E-10 T 14-10-2018 IPR036259 MFS transporter superfamily D521_1838 0623be306f4d5dfd0ed550cc44551ca6 556 SUPERFAMILY SSF103473 10 328 1.11E-52 T 14-10-2018 IPR036259 MFS transporter superfamily D521_1838 0623be306f4d5dfd0ed550cc44551ca6 556 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 D521_1838 0623be306f4d5dfd0ed550cc44551ca6 556 Gene3D G3DSA:1.20.1250.20 434 555 4.3E-11 T 14-10-2018 D521_1838 0623be306f4d5dfd0ed550cc44551ca6 556 Gene3D G3DSA:1.20.1250.20 14 413 1.4E-52 T 14-10-2018 D521_0010 a3bc1261041dc750e58e18677b1d3a14 309 Pfam PF02653 Branched-chain amino acid transport system / permease component 29 289 2.1E-36 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 D521_0476 6dc4bb144f97231f84f70d026f30cf6f 1208 SMART SM00481 7 74 1.2E-21 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal D521_0476 6dc4bb144f97231f84f70d026f30cf6f 1208 Gene3D G3DSA:1.10.10.1600 447 526 6.0E-26 T 14-10-2018 D521_0476 6dc4bb144f97231f84f70d026f30cf6f 1208 Pfam PF02811 PHP domain 8 185 2.1E-42 T 14-10-2018 IPR004013 PHP domain GO:0003824 D521_0476 6dc4bb144f97231f84f70d026f30cf6f 1208 SUPERFAMILY SSF89550 6 276 2.09E-11 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 D521_0476 6dc4bb144f97231f84f70d026f30cf6f 1208 Pfam PF14579 Helix-hairpin-helix motif 823 916 2.2E-23 T 14-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_0476 6dc4bb144f97231f84f70d026f30cf6f 1208 Gene3D G3DSA:3.20.20.140 1 283 4.8E-81 T 14-10-2018 D521_0476 6dc4bb144f97231f84f70d026f30cf6f 1208 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 305 747 2.9E-173 T 14-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_0476 6dc4bb144f97231f84f70d026f30cf6f 1208 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 1057 0.0 T 14-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1695 cc59e7b5ee01b96df7e04dcaeccf596a 77 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 23 62 7.0E-7 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 D521_1695 cc59e7b5ee01b96df7e04dcaeccf596a 77 SUPERFAMILY SSF116842 19 75 2.35E-17 T 14-10-2018 D521_1695 cc59e7b5ee01b96df7e04dcaeccf596a 77 Gene3D G3DSA:1.10.287.1040 18 77 8.0E-19 T 14-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 D521_1695 cc59e7b5ee01b96df7e04dcaeccf596a 77 Pfam PF02609 Exonuclease VII small subunit 23 73 3.9E-18 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 D521_1695 cc59e7b5ee01b96df7e04dcaeccf596a 77 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 22 77 11.938 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 D521_1695 cc59e7b5ee01b96df7e04dcaeccf596a 77 PIRSF PIRSF006488 12 77 1.2E-20 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 D521_1695 cc59e7b5ee01b96df7e04dcaeccf596a 77 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 23 73 3.1E-19 T 14-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 D521_1347 e48b5b012023069450da4044f9fcf782 621 Pfam PF00012 Hsp70 protein 21 604 3.6E-176 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 24 31 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 SUPERFAMILY SSF53067 19 195 1.31E-50 T 14-10-2018 D521_1347 e48b5b012023069450da4044f9fcf782 621 SUPERFAMILY SSF100934 508 619 1.22E-27 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 SUPERFAMILY SSF100920 386 537 1.7E-48 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 Gene3D G3DSA:1.20.1270.10 524 620 1.8E-21 T 14-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 Gene3D G3DSA:3.90.640.10 237 314 4.6E-111 T 14-10-2018 D521_1347 e48b5b012023069450da4044f9fcf782 621 SUPERFAMILY SSF53067 199 380 2.2E-48 T 14-10-2018 D521_1347 e48b5b012023069450da4044f9fcf782 621 TIGRFAM TIGR01991 HscA: Fe-S protein assembly chaperone HscA 21 619 2.2E-268 T 14-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 D521_1347 e48b5b012023069450da4044f9fcf782 621 PRINTS PR00301 70kDa heat shock protein signature 389 408 4.7E-56 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 PRINTS PR00301 70kDa heat shock protein signature 210 220 4.7E-56 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 PRINTS PR00301 70kDa heat shock protein signature 470 486 4.7E-56 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 PRINTS PR00301 70kDa heat shock protein signature 48 60 4.7E-56 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 PRINTS PR00301 70kDa heat shock protein signature 332 348 4.7E-56 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 PRINTS PR00301 70kDa heat shock protein signature 20 33 4.7E-56 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 PRINTS PR00301 70kDa heat shock protein signature 151 171 4.7E-56 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 PRINTS PR00301 70kDa heat shock protein signature 363 383 4.7E-56 T 14-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 335 349 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 Gene3D G3DSA:2.60.34.10 393 521 1.6E-50 T 14-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 D521_1347 e48b5b012023069450da4044f9fcf782 621 Gene3D G3DSA:3.30.420.40 22 377 4.6E-111 T 14-10-2018 D521_1347 e48b5b012023069450da4044f9fcf782 621 Gene3D G3DSA:3.30.420.40 193 364 4.6E-111 T 14-10-2018 D521_1347 e48b5b012023069450da4044f9fcf782 621 Hamap MF_00679 Chaperone protein HscA [hscA]. 1 621 42.216 T 14-10-2018 IPR010236 ISC system FeS cluster assembly, HscA chaperone GO:0005524|GO:0006457|GO:0016226|GO:0016887|GO:0051082 D521_1347 e48b5b012023069450da4044f9fcf782 621 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 204 217 - T 14-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 D521_1981 29728d906cdaaa6414061cbb31cb7b1d 58 Pfam PF06945 Protein of unknown function (DUF1289) 6 53 1.5E-20 T 14-10-2018 IPR010710 Protein of unknown function DUF1289 D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 12 223 2.5E-70 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 Pfam PF00035 Double-stranded RNA binding motif 160 223 1.5E-9 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 SUPERFAMILY SSF69065 4 149 9.42E-48 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 SUPERFAMILY SSF54768 112 226 1.73E-22 T 14-10-2018 D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 Gene3D G3DSA:3.30.160.20 157 232 8.4E-16 T 14-10-2018 D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 Pfam PF14622 Ribonuclease-III-like 24 141 1.4E-36 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 ProSitePatterns PS00517 Ribonuclease III family signature. 41 49 - T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 Gene3D G3DSA:1.10.1520.10 5 149 1.5E-45 T 14-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 SMART SM00358 159 227 3.0E-13 T 14-10-2018 IPR014720 Double-stranded RNA-binding domain D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 SMART SM00535 24 152 3.5E-49 T 14-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 D521_1420 de52d4584482b5cc1ea73b78b78a8226 263 Hamap MF_00104 Ribonuclease 3 [rnc]. 12 223 29.126 T 14-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 D521_1381 1c4f33bba1fb90545734d4efce0c6cb6 81 Gene3D G3DSA:3.10.20.30 1 81 2.1E-22 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_1381 1c4f33bba1fb90545734d4efce0c6cb6 81 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 1 81 4.5E-23 T 14-10-2018 D521_1381 1c4f33bba1fb90545734d4efce0c6cb6 81 Pfam PF02597 ThiS family 2 81 6.3E-19 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 D521_1381 1c4f33bba1fb90545734d4efce0c6cb6 81 SUPERFAMILY SSF54285 1 81 9.35E-19 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp D521_0774 6a2ae139a9e6f4c84b517997137872c8 261 Pfam PF08241 Methyltransferase domain 69 129 4.4E-12 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 D521_0774 6a2ae139a9e6f4c84b517997137872c8 261 SUPERFAMILY SSF53335 71 221 1.11E-17 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0774 6a2ae139a9e6f4c84b517997137872c8 261 Gene3D G3DSA:3.40.50.150 51 179 1.1E-17 T 14-10-2018 D521_2020 8044efc260efe0b8e4c0fd32ec0fa3c7 490 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 489 2.4E-168 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 D521_2020 8044efc260efe0b8e4c0fd32ec0fa3c7 490 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 3 490 37.227 T 14-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 D521_2020 8044efc260efe0b8e4c0fd32ec0fa3c7 490 Gene3D G3DSA:1.10.10.410 429 490 5.2E-27 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal D521_2020 8044efc260efe0b8e4c0fd32ec0fa3c7 490 SMART SM00845 334 489 9.6E-70 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 D521_2020 8044efc260efe0b8e4c0fd32ec0fa3c7 490 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 150 164 - T 14-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 D521_2020 8044efc260efe0b8e4c0fd32ec0fa3c7 490 Pfam PF02934 GatB/GatE catalytic domain 6 294 1.0E-112 T 14-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 D521_2020 8044efc260efe0b8e4c0fd32ec0fa3c7 490 Gene3D G3DSA:1.10.150.380 303 428 1.1E-23 T 14-10-2018 D521_2020 8044efc260efe0b8e4c0fd32ec0fa3c7 490 SUPERFAMILY SSF89095 304 407 3.01E-25 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 D521_2020 8044efc260efe0b8e4c0fd32ec0fa3c7 490 SUPERFAMILY SSF55931 5 302 4.77E-121 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 D521_2020 8044efc260efe0b8e4c0fd32ec0fa3c7 490 Pfam PF02637 GatB domain 335 489 1.3E-46 T 14-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 D521_1614 684545d0bea3b2b0f2b90033e151bfa4 546 SUPERFAMILY SSF52540 325 522 8.77E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1614 684545d0bea3b2b0f2b90033e151bfa4 546 Gene3D G3DSA:3.40.50.300 306 489 3.2E-26 T 14-10-2018 D521_1614 684545d0bea3b2b0f2b90033e151bfa4 546 SMART SM00382 345 469 0.0051 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1614 684545d0bea3b2b0f2b90033e151bfa4 546 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 350 468 8.6E-15 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 D521_1419 29f0db729571511e88ed880df1ce93d0 311 Gene3D G3DSA:3.40.50.300 2 200 7.0E-38 T 14-10-2018 D521_1419 29f0db729571511e88ed880df1ce93d0 311 Pfam PF01926 50S ribosome-binding GTPase 7 120 1.5E-21 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_1419 29f0db729571511e88ed880df1ce93d0 311 TIGRFAM TIGR00436 era: GTP-binding protein Era 5 293 5.0E-74 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1419 29f0db729571511e88ed880df1ce93d0 311 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 152 6.3E-25 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 D521_1419 29f0db729571511e88ed880df1ce93d0 311 Pfam PF07650 KH domain 223 298 9.5E-17 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_1419 29f0db729571511e88ed880df1ce93d0 311 Hamap MF_00367 GTPase Era [era]. 2 310 33.137 T 14-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1419 29f0db729571511e88ed880df1ce93d0 311 SUPERFAMILY SSF52540 6 220 2.02E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1419 29f0db729571511e88ed880df1ce93d0 311 Gene3D G3DSA:3.30.300.20 201 311 1.0E-36 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta D521_1419 29f0db729571511e88ed880df1ce93d0 311 SUPERFAMILY SSF54814 197 310 1.44E-37 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 D521_1901 438603763a3ee7494b23249592c0769e 962 Gene3D G3DSA:3.40.50.300 7 608 3.0E-244 T 14-10-2018 D521_1901 438603763a3ee7494b23249592c0769e 962 SUPERFAMILY SSF52540 631 923 2.32E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1901 438603763a3ee7494b23249592c0769e 962 SUPERFAMILY SSF52540 5 582 3.12E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1901 438603763a3ee7494b23249592c0769e 962 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 951 22.253 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 D521_1901 438603763a3ee7494b23249592c0769e 962 Gene3D G3DSA:1.20.1580.10 91 505 3.0E-244 T 14-10-2018 D521_1901 438603763a3ee7494b23249592c0769e 962 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 936 0.0 T 14-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 D521_1901 438603763a3ee7494b23249592c0769e 962 Gene3D G3DSA:1.20.1580.10 704 841 2.3E-139 T 14-10-2018 D521_1901 438603763a3ee7494b23249592c0769e 962 ProSitePatterns PS00211 ABC transporters family signature. 841 855 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_1901 438603763a3ee7494b23249592c0769e 962 Gene3D G3DSA:3.40.50.300 625 947 2.3E-139 T 14-10-2018 D521_1901 438603763a3ee7494b23249592c0769e 962 ProSitePatterns PS00211 ABC transporters family signature. 500 514 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_1901 438603763a3ee7494b23249592c0769e 962 Gene3D G3DSA:1.10.8.280 296 412 3.0E-244 T 14-10-2018 D521_1901 438603763a3ee7494b23249592c0769e 962 Gene3D G3DSA:3.30.190.20 131 253 3.0E-244 T 14-10-2018 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 432 39.28 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 235 409 5.1E-34 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 6.3E-28 T 14-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 Gene3D G3DSA:1.10.287.40 1 104 6.6E-18 T 14-10-2018 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 SUPERFAMILY SSF46589 1 112 8.37E-26 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 PRINTS PR00981 Seryl-tRNA synthetase signature 362 378 1.6E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 PRINTS PR00981 Seryl-tRNA synthetase signature 344 360 1.6E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 PRINTS PR00981 Seryl-tRNA synthetase signature 287 300 1.6E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 PRINTS PR00981 Seryl-tRNA synthetase signature 327 340 1.6E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 PRINTS PR00981 Seryl-tRNA synthetase signature 275 287 1.6E-32 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 Gene3D G3DSA:3.30.930.10 105 435 3.1E-114 T 14-10-2018 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 427 4.8E-159 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 SUPERFAMILY SSF55681 116 428 3.59E-100 T 14-10-2018 D521_0555 15a5e651b6f1a0fa76893192e9275e4a 436 PIRSF PIRSF001529 1 435 3.0E-171 T 14-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 D521_1172 f1878d3ff795bb1e799dd514b02b8826 412 Pfam PF01494 FAD binding domain 293 362 4.7E-6 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 D521_1172 f1878d3ff795bb1e799dd514b02b8826 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 299 314 2.2E-15 T 14-10-2018 D521_1172 f1878d3ff795bb1e799dd514b02b8826 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 137 152 2.2E-15 T 14-10-2018 D521_1172 f1878d3ff795bb1e799dd514b02b8826 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.2E-15 T 14-10-2018 D521_1172 f1878d3ff795bb1e799dd514b02b8826 412 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 347 363 2.2E-15 T 14-10-2018 D521_1172 f1878d3ff795bb1e799dd514b02b8826 412 Gene3D G3DSA:3.50.50.60 4 353 1.2E-103 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1172 f1878d3ff795bb1e799dd514b02b8826 412 SUPERFAMILY SSF54373 161 292 6.28E-39 T 14-10-2018 D521_1172 f1878d3ff795bb1e799dd514b02b8826 412 SUPERFAMILY SSF51905 3 373 1.12E-39 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1172 f1878d3ff795bb1e799dd514b02b8826 412 Gene3D G3DSA:3.30.9.60 70 288 1.2E-103 T 14-10-2018 D521_0190 26e434d19fa6a01ce2d9c04073520946 325 Gene3D G3DSA:1.10.600.10 8 322 3.4E-72 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily D521_0190 26e434d19fa6a01ce2d9c04073520946 325 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 157 172 - T 14-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 D521_0190 26e434d19fa6a01ce2d9c04073520946 325 Pfam PF00494 Squalene/phytoene synthase 20 225 1.2E-29 T 14-10-2018 D521_0190 26e434d19fa6a01ce2d9c04073520946 325 SUPERFAMILY SSF48576 10 300 1.24E-39 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily D521_0974 463244d6582945289cc47597087e838b 145 Pfam PF04143 Sulphur transport 10 132 1.3E-6 T 14-10-2018 IPR007272 Sulphur transport domain D521_1683 40ee876b817e3f618f7a8f452fdb92a1 233 Gene3D G3DSA:1.10.10.10 23 91 2.0E-23 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1683 40ee876b817e3f618f7a8f452fdb92a1 233 SUPERFAMILY SSF48008 96 229 4.97E-16 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal D521_1683 40ee876b817e3f618f7a8f452fdb92a1 233 SMART SM00345 31 89 6.6E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1683 40ee876b817e3f618f7a8f452fdb92a1 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 2.0E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1683 40ee876b817e3f618f7a8f452fdb92a1 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 2.0E-6 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1683 40ee876b817e3f618f7a8f452fdb92a1 233 SMART SM00895 99 222 1.3E-11 T 14-10-2018 IPR011711 GntR, C-terminal D521_1683 40ee876b817e3f618f7a8f452fdb92a1 233 SUPERFAMILY SSF46785 25 93 8.06E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1683 40ee876b817e3f618f7a8f452fdb92a1 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 27 89 6.0E-20 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1683 40ee876b817e3f618f7a8f452fdb92a1 233 Gene3D G3DSA:1.20.120.530 93 229 1.4E-18 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal D521_1683 40ee876b817e3f618f7a8f452fdb92a1 233 Pfam PF07729 FCD domain 100 221 3.2E-17 T 14-10-2018 IPR011711 GntR, C-terminal D521_0933 d3dfad13b6b4743d27025b02da0b8c30 488 Pfam PF13624 SurA N-terminal domain 1 160 3.9E-31 T 14-10-2018 D521_0933 d3dfad13b6b4743d27025b02da0b8c30 488 SUPERFAMILY SSF109998 42 244 8.24E-18 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily D521_0933 d3dfad13b6b4743d27025b02da0b8c30 488 Pfam PF13145 PPIC-type PPIASE domain 204 343 2.3E-6 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 Gene3D G3DSA:3.30.479.20 153 268 1.1E-38 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 14-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 Gene3D G3DSA:3.30.479.20 57 147 2.3E-25 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 Gene3D G3DSA:1.10.286.20 188 234 1.1E-38 T 14-10-2018 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 286 3.7E-91 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 SUPERFAMILY SSF54713 150 286 5.05E-49 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 Gene3D G3DSA:1.10.8.10 1 56 1.4E-19 T 14-10-2018 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 Pfam PF00889 Elongation factor TS 71 269 4.6E-68 T 14-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 SUPERFAMILY SSF46934 3 56 2.45E-13 T 14-10-2018 IPR009060 UBA-like superfamily GO:0005515 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 SUPERFAMILY SSF54713 56 144 1.96E-21 T 14-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 D521_1260 e91db2cd0e5cc8d3313cda042e96caf7 292 Hamap MF_00050 Elongation factor Ts [tsf]. 1 286 77.615 T 14-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 D521_1974 72d7de5f4762b55189df87306d308440 204 SUPERFAMILY SSF110997 125 200 8.89E-17 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 D521_1974 72d7de5f4762b55189df87306d308440 204 Pfam PF05036 Sporulation related domain 129 200 2.6E-16 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 D521_1974 72d7de5f4762b55189df87306d308440 204 Gene3D G3DSA:3.30.70.1070 122 203 1.1E-15 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 D521_0228 ee68ff46d455725673249472f313a361 206 Pfam PF01337 Barstar (barnase inhibitor) 111 194 3.8E-16 T 14-10-2018 IPR000468 Barstar (barnase inhibitor) D521_0228 ee68ff46d455725673249472f313a361 206 SUPERFAMILY SSF52038 107 198 9.68E-13 T 14-10-2018 IPR035905 Barstar-like superfamily D521_0407 e0fbbe98f3f788779df41c55d1c4efb2 139 PRINTS PR00421 Thioredoxin family signature 55 63 5.7E-9 T 14-10-2018 D521_0407 e0fbbe98f3f788779df41c55d1c4efb2 139 PRINTS PR00421 Thioredoxin family signature 63 72 5.7E-9 T 14-10-2018 D521_0407 e0fbbe98f3f788779df41c55d1c4efb2 139 PRINTS PR00421 Thioredoxin family signature 103 114 5.7E-9 T 14-10-2018 D521_0407 e0fbbe98f3f788779df41c55d1c4efb2 139 Gene3D G3DSA:3.40.30.10 36 139 1.5E-27 T 14-10-2018 D521_0407 e0fbbe98f3f788779df41c55d1c4efb2 139 TIGRFAM TIGR01068 thioredoxin: thioredoxin 40 135 4.8E-30 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 D521_0407 e0fbbe98f3f788779df41c55d1c4efb2 139 ProSitePatterns PS00194 Thioredoxin family active site. 56 74 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 D521_0407 e0fbbe98f3f788779df41c55d1c4efb2 139 Gene3D G3DSA:2.20.28.140 1 33 2.3E-9 T 14-10-2018 D521_0407 e0fbbe98f3f788779df41c55d1c4efb2 139 Pfam PF00085 Thioredoxin 40 135 1.8E-25 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 D521_0407 e0fbbe98f3f788779df41c55d1c4efb2 139 SUPERFAMILY SSF52833 40 139 3.71E-31 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0407 e0fbbe98f3f788779df41c55d1c4efb2 139 PIRSF PIRSF000077 35 139 2.2E-28 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 D521_1602 ce47f6e4968019c8ef8e387d2ee951e1 249 Gene3D G3DSA:3.40.50.620 1 247 2.5E-87 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1602 ce47f6e4968019c8ef8e387d2ee951e1 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 D521_1602 ce47f6e4968019c8ef8e387d2ee951e1 249 SMART SM00893 23 211 1.4E-67 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 D521_1602 ce47f6e4968019c8ef8e387d2ee951e1 249 PIRSF PIRSF000090 1 249 4.3E-86 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 D521_1602 ce47f6e4968019c8ef8e387d2ee951e1 249 Pfam PF01012 Electron transfer flavoprotein domain 29 206 6.6E-45 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 D521_1602 ce47f6e4968019c8ef8e387d2ee951e1 249 SUPERFAMILY SSF52402 1 242 7.67E-86 T 14-10-2018 D521_1581 ce47f6e4968019c8ef8e387d2ee951e1 249 Gene3D G3DSA:3.40.50.620 1 247 2.5E-87 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1581 ce47f6e4968019c8ef8e387d2ee951e1 249 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 D521_1581 ce47f6e4968019c8ef8e387d2ee951e1 249 SMART SM00893 23 211 1.4E-67 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 D521_1581 ce47f6e4968019c8ef8e387d2ee951e1 249 PIRSF PIRSF000090 1 249 4.3E-86 T 14-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 D521_1581 ce47f6e4968019c8ef8e387d2ee951e1 249 Pfam PF01012 Electron transfer flavoprotein domain 29 206 6.6E-45 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 D521_1581 ce47f6e4968019c8ef8e387d2ee951e1 249 SUPERFAMILY SSF52402 1 242 7.67E-86 T 14-10-2018 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 SUPERFAMILY SSF64484 17 1373 0.0 T 14-10-2018 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Gene3D G3DSA:2.40.50.100 957 1032 9.6E-28 T 14-10-2018 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Gene3D G3DSA:2.40.50.100 1161 1224 4.2E-67 T 14-10-2018 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Gene3D G3DSA:1.10.274.100 494 649 1.2E-38 T 14-10-2018 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Gene3D G3DSA:1.10.132.30 650 799 2.1E-63 T 14-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Gene3D G3DSA:1.10.1790.20 1145 1323 4.2E-67 T 14-10-2018 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 SMART SM00663 239 518 2.8E-174 T 14-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Pfam PF04983 RNA polymerase Rpb1, domain 3 493 653 5.9E-23 T 14-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1386 18.711 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Gene3D G3DSA:2.40.50.100 1033 1136 1.5E-28 T 14-10-2018 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Gene3D G3DSA:1.10.40.90 378 420 2.9E-19 T 14-10-2018 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Gene3D G3DSA:1.10.150.390 1325 1386 4.0E-29 T 14-10-2018 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Pfam PF04997 RNA polymerase Rpb1, domain 1 16 346 2.1E-87 T 14-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Pfam PF04998 RNA polymerase Rpb1, domain 5 775 1325 1.4E-75 T 14-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Pfam PF05000 RNA polymerase Rpb1, domain 4 683 772 1.9E-17 T 14-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 20 1375 0.0 T 14-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Pfam PF00623 RNA polymerase Rpb1, domain 2 348 389 1.4E-7 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0045 cb189bedf08fcb5eb7d76a933b9b2e11 1420 Pfam PF00623 RNA polymerase Rpb1, domain 2 395 489 4.8E-27 T 14-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0589 1cb825d6a8b48fcb879d6823fb555887 425 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 33 151 1.1E-12 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 D521_0589 1cb825d6a8b48fcb879d6823fb555887 425 SUPERFAMILY SSF55424 357 425 6.04E-20 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 D521_0589 1cb825d6a8b48fcb879d6823fb555887 425 Gene3D G3DSA:3.90.760.10 357 425 6.1E-9 T 14-10-2018 IPR037092 Flavocytochrome c sulphide dehydrogenase, flavin-binding domain superfamily GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 D521_0589 1cb825d6a8b48fcb879d6823fb555887 425 Gene3D G3DSA:3.50.50.60 34 345 2.7E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0589 1cb825d6a8b48fcb879d6823fb555887 425 SUPERFAMILY SSF51905 157 280 3.45E-35 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0589 1cb825d6a8b48fcb879d6823fb555887 425 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 358 423 6.3E-22 T 14-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 D521_0589 1cb825d6a8b48fcb879d6823fb555887 425 SUPERFAMILY SSF51905 32 157 1.99E-24 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0589 1cb825d6a8b48fcb879d6823fb555887 425 Gene3D G3DSA:3.50.50.60 148 281 2.7E-101 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1437 b1ca785b9e36317ebf09f4beb08749ac 339 SUPERFAMILY SSF55174 31 82 2.88E-9 T 14-10-2018 D521_1437 b1ca785b9e36317ebf09f4beb08749ac 339 SUPERFAMILY SSF55120 107 334 3.2E-59 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1437 b1ca785b9e36317ebf09f4beb08749ac 339 Gene3D G3DSA:3.30.2350.10 110 335 4.5E-68 T 14-10-2018 D521_1437 b1ca785b9e36317ebf09f4beb08749ac 339 Pfam PF01479 S4 domain 32 78 1.1E-8 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_1437 b1ca785b9e36317ebf09f4beb08749ac 339 SMART SM00363 32 90 1.5E-6 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_1437 b1ca785b9e36317ebf09f4beb08749ac 339 Pfam PF00849 RNA pseudouridylate synthase 119 272 2.5E-28 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1437 b1ca785b9e36317ebf09f4beb08749ac 339 Gene3D G3DSA:3.10.290.10 21 84 3.8E-14 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 D521_1437 b1ca785b9e36317ebf09f4beb08749ac 339 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 28 332 1.1E-70 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1437 b1ca785b9e36317ebf09f4beb08749ac 339 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 157 171 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_1802 b9f4afc640f484c8c89fd7901a256468 275 Pfam PF00563 EAL domain 72 244 1.7E-5 T 14-10-2018 IPR001633 EAL domain D521_1802 b9f4afc640f484c8c89fd7901a256468 275 Gene3D G3DSA:3.20.20.450 57 260 8.0E-11 T 14-10-2018 IPR035919 EAL domain superfamily D521_1802 b9f4afc640f484c8c89fd7901a256468 275 SUPERFAMILY SSF141868 84 253 1.96E-10 T 14-10-2018 IPR035919 EAL domain superfamily D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 SUPERFAMILY SSF51905 7 431 1.67E-74 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 SUPERFAMILY SSF46977 457 592 1.7E-44 T 14-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 Gene3D G3DSA:3.50.50.60 14 420 8.6E-163 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 11 592 2.7E-277 T 14-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 Gene3D G3DSA:3.90.700.10 251 354 8.6E-163 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 Pfam PF02910 Fumarate reductase flavoprotein C-term 466 591 1.8E-39 T 14-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 SUPERFAMILY SSF56425 241 359 1.23E-43 T 14-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 Pfam PF00890 FAD binding domain 14 409 8.4E-115 T 14-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 Gene3D G3DSA:1.20.58.100 438 551 6.3E-31 T 14-10-2018 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 PIRSF PIRSF000171 4 578 1.6E-40 T 14-10-2018 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 48 57 - T 14-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 14 591 1.5E-235 T 14-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 387 394 5.4E-6 T 14-10-2018 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 14 36 5.4E-6 T 14-10-2018 D521_1010 d01325dd9f5bbb9bb2b7c146d2b6afc0 592 Gene3D G3DSA:4.10.80.40 552 592 3.3E-10 T 14-10-2018 D521_0060 bcaf7d724366483371ec55ba12cd3c89 64 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 15.44 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0060 bcaf7d724366483371ec55ba12cd3c89 64 Gene3D G3DSA:1.10.287.310 1 62 1.9E-19 T 14-10-2018 D521_0060 bcaf7d724366483371ec55ba12cd3c89 64 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 1.4E-14 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0060 bcaf7d724366483371ec55ba12cd3c89 64 Pfam PF00831 Ribosomal L29 protein 5 60 5.7E-16 T 14-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0060 bcaf7d724366483371ec55ba12cd3c89 64 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 14-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0060 bcaf7d724366483371ec55ba12cd3c89 64 SUPERFAMILY SSF46561 1 61 4.58E-16 T 14-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_1643 972a08b2159f680d8aec535f754efa2f 188 Pfam PF00589 Phage integrase family 5 177 3.2E-24 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 D521_1643 972a08b2159f680d8aec535f754efa2f 188 Gene3D G3DSA:1.10.443.10 2 188 2.1E-36 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 D521_1643 972a08b2159f680d8aec535f754efa2f 188 SUPERFAMILY SSF56349 5 185 3.24E-38 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 SUPERFAMILY SSF50249 65 125 2.06E-14 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 119 5.8E-17 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 SUPERFAMILY SSF50104 1 63 2.06E-15 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 1.2E-60 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 SUPERFAMILY SSF50249 129 185 3.26E-15 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 Gene3D G3DSA:2.40.50.140 64 125 8.0E-20 T 14-10-2018 D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.3E-16 T 14-10-2018 IPR013185 Translation elongation factor, KOW-like D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 Hamap MF_00141 Elongation factor P [efp]. 1 185 46.165 T 14-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 14-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 Pfam PF09285 Elongation factor P, C-terminal 129 184 4.4E-25 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 Gene3D G3DSA:2.40.50.140 127 186 9.1E-27 T 14-10-2018 D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 SMART SM00841 128 184 4.9E-30 T 14-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 SMART SM01185 67 120 2.0E-19 T 14-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 PIRSF PIRSF005901 1 186 7.4E-52 T 14-10-2018 IPR020599 Translation elongation factor P/YeiP D521_1414 d35ad2d38f86e0a066f3676d15a872ba 186 Gene3D G3DSA:2.30.30.30 1 62 4.5E-16 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 D521_0515 c27a99a9c1b68e7ebb813c5d508fe511 282 Pfam PF02634 FdhD/NarQ family 36 273 8.4E-72 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 D521_0515 c27a99a9c1b68e7ebb813c5d508fe511 282 Gene3D G3DSA:3.40.140.10 126 278 1.5E-36 T 14-10-2018 D521_0515 c27a99a9c1b68e7ebb813c5d508fe511 282 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 14 274 27.103 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 D521_0515 c27a99a9c1b68e7ebb813c5d508fe511 282 PIRSF PIRSF015626 3 277 7.0E-73 T 14-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 D521_0515 c27a99a9c1b68e7ebb813c5d508fe511 282 SUPERFAMILY SSF53927 17 274 6.92E-65 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 D521_0515 c27a99a9c1b68e7ebb813c5d508fe511 282 Gene3D G3DSA:3.10.20.10 37 120 9.7E-11 T 14-10-2018 D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 Pfam PF00226 DnaJ domain 5 66 3.0E-25 T 14-10-2018 IPR001623 DnaJ domain D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 Gene3D G3DSA:2.60.260.20 213 291 8.4E-24 T 14-10-2018 D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 SMART SM00271 4 61 3.2E-28 T 14-10-2018 IPR001623 DnaJ domain D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 Gene3D G3DSA:2.60.260.20 132 211 3.1E-19 T 14-10-2018 D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 PRINTS PR00625 DnaJ domain signature 7 25 5.3E-24 T 14-10-2018 IPR001623 DnaJ domain D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 PRINTS PR00625 DnaJ domain signature 61 80 5.3E-24 T 14-10-2018 IPR001623 DnaJ domain D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 PRINTS PR00625 DnaJ domain signature 41 61 5.3E-24 T 14-10-2018 IPR001623 DnaJ domain D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 PRINTS PR00625 DnaJ domain signature 25 40 5.3E-24 T 14-10-2018 IPR001623 DnaJ domain D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 Gene3D G3DSA:1.10.287.110 1 71 4.0E-29 T 14-10-2018 IPR036869 Chaperone J-domain superfamily D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 14-10-2018 IPR018253 DnaJ domain, conserved site D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 SUPERFAMILY SSF49493 131 219 3.79E-14 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 SUPERFAMILY SSF46565 1 72 6.67E-32 T 14-10-2018 IPR036869 Chaperone J-domain superfamily D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 Pfam PF01556 DnaJ C terminal domain 138 291 5.6E-32 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal D521_0579 dab3caf0c501ef269c7b68ef88b04657 319 SUPERFAMILY SSF49493 219 302 6.8E-18 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 SUPERFAMILY SSF55021 792 842 1.45E-8 T 14-10-2018 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 SUPERFAMILY SSF81301 18 159 7.8E-20 T 14-10-2018 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 865 301.898 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 SUPERFAMILY SSF109604 410 535 4.08E-13 T 14-10-2018 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 SUPERFAMILY SSF55021 680 737 1.07E-8 T 14-10-2018 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 20 861 2.9E-240 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 Pfam PF08335 GlnD PII-uridylyltransferase 167 305 3.1E-31 T 14-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 SUPERFAMILY SSF81593 174 291 3.84E-7 T 14-10-2018 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 Pfam PF01909 Nucleotidyltransferase domain 58 101 1.1E-5 T 14-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 Gene3D G3DSA:1.10.3210.10 425 562 7.5E-8 T 14-10-2018 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 Gene3D G3DSA:3.30.70.260 792 864 3.2E-7 T 14-10-2018 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 PIRSF PIRSF006288 2 865 6.5E-294 T 14-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 Pfam PF01966 HD domain 447 549 2.9E-10 T 14-10-2018 IPR006674 HD domain D521_1263 7b9959b47b4c3a57268cf06240b077cd 865 SMART SM00471 442 589 1.2E-4 T 14-10-2018 IPR003607 HD/PDEase domain D521_1913 04d8e3868a1e4c61ed7e124c834c698c 344 SMART SM00478 1 154 1.1E-49 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 D521_1913 04d8e3868a1e4c61ed7e124c834c698c 344 Pfam PF14815 NUDIX domain 204 332 1.7E-21 T 14-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 D521_1913 04d8e3868a1e4c61ed7e124c834c698c 344 SUPERFAMILY SSF55811 188 332 4.77E-18 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 D521_1913 04d8e3868a1e4c61ed7e124c834c698c 344 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 1 129 4.3E-18 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 D521_1913 04d8e3868a1e4c61ed7e124c834c698c 344 Gene3D G3DSA:1.10.1670.10 95 179 1.6E-65 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 D521_1913 04d8e3868a1e4c61ed7e124c834c698c 344 Gene3D G3DSA:1.10.340.30 1 94 1.6E-65 T 14-10-2018 D521_1913 04d8e3868a1e4c61ed7e124c834c698c 344 SUPERFAMILY SSF48150 1 190 2.98E-54 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 D521_1913 04d8e3868a1e4c61ed7e124c834c698c 344 Gene3D G3DSA:3.90.79.10 193 336 5.2E-17 T 14-10-2018 D521_0548 a5e70d21abc0ff8cd8895e2b54ba5272 541 Pfam PF00795 Carbon-nitrogen hydrolase 7 247 8.8E-22 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 D521_0548 a5e70d21abc0ff8cd8895e2b54ba5272 541 PIRSF PIRSF006630 3 541 3.5E-193 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 D521_0548 a5e70d21abc0ff8cd8895e2b54ba5272 541 Gene3D G3DSA:3.60.110.10 3 255 8.8E-85 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily D521_0548 a5e70d21abc0ff8cd8895e2b54ba5272 541 Gene3D G3DSA:3.40.50.620 265 541 3.7E-118 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0548 a5e70d21abc0ff8cd8895e2b54ba5272 541 SUPERFAMILY SSF52402 262 524 3.09E-76 T 14-10-2018 D521_0548 a5e70d21abc0ff8cd8895e2b54ba5272 541 Pfam PF02540 NAD synthase 268 516 3.2E-73 T 14-10-2018 IPR022310 NAD/GMP synthase D521_0548 a5e70d21abc0ff8cd8895e2b54ba5272 541 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 6 541 28.674 T 14-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 D521_0548 a5e70d21abc0ff8cd8895e2b54ba5272 541 SUPERFAMILY SSF56317 6 248 1.96E-54 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily D521_0548 a5e70d21abc0ff8cd8895e2b54ba5272 541 TIGRFAM TIGR00552 nadE: NAD+ synthetase 275 519 6.1E-62 T 14-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 D521_1147 c24af8b47548d35b153f3453b17090e8 453 SMART SM00849 3 225 2.2E-7 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_1147 c24af8b47548d35b153f3453b17090e8 453 Pfam PF10996 Beta-Casp domain 242 367 3.0E-23 T 14-10-2018 IPR022712 Beta-Casp domain D521_1147 c24af8b47548d35b153f3453b17090e8 453 SMART SM01027 242 367 3.2E-48 T 14-10-2018 IPR022712 Beta-Casp domain D521_1147 c24af8b47548d35b153f3453b17090e8 453 Gene3D G3DSA:3.40.50.10890 210 393 2.5E-131 T 14-10-2018 D521_1147 c24af8b47548d35b153f3453b17090e8 453 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 381 443 7.1E-17 T 14-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain D521_1147 c24af8b47548d35b153f3453b17090e8 453 Gene3D G3DSA:3.60.15.10 9 427 2.5E-131 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_1147 c24af8b47548d35b153f3453b17090e8 453 SUPERFAMILY SSF56281 9 448 6.63E-111 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_1147 c24af8b47548d35b153f3453b17090e8 453 Pfam PF00753 Metallo-beta-lactamase superfamily 7 105 5.1E-11 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0247 925b022b52e102ecdd7b5f80c8c7c65c 141 SMART SM00732 11 111 3.7E-19 T 14-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 D521_0247 925b022b52e102ecdd7b5f80c8c7c65c 141 SUPERFAMILY SSF53098 12 134 2.88E-31 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_0247 925b022b52e102ecdd7b5f80c8c7c65c 141 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 11 138 20.225 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 D521_0247 925b022b52e102ecdd7b5f80c8c7c65c 141 Pfam PF03652 Holliday junction resolvase 12 134 4.3E-32 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 D521_0247 925b022b52e102ecdd7b5f80c8c7c65c 141 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 14 134 3.5E-24 T 14-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 D521_0247 925b022b52e102ecdd7b5f80c8c7c65c 141 Gene3D G3DSA:3.30.420.140 10 137 5.2E-33 T 14-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 SMART SM00836 600 702 0.001 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 Gene3D G3DSA:1.10.730.10 598 704 4.9E-5 T 14-10-2018 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 SUPERFAMILY SSF109604 358 512 1.05E-17 T 14-10-2018 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 SUPERFAMILY SSF47323 607 704 2.16E-5 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 10 711 2.1E-185 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 Pfam PF05746 DALR anticodon binding domain 605 703 8.5E-12 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 10 711 23.243 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 335 351 1.1E-32 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 14 27 1.1E-32 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 59 71 1.1E-32 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 411 430 1.1E-32 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 263 278 1.1E-32 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_1858 3e468eed8d32f414e6e2ec6cb2c35b99 712 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 13 573 1.4E-189 T 14-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 D521_0038 deb5e92b057427700d861a408413b529 125 PRINTS PR01650 Bacterial translocase SecE signature 63 83 3.9E-12 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 D521_0038 deb5e92b057427700d861a408413b529 125 PRINTS PR01650 Bacterial translocase SecE signature 42 63 3.9E-12 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 D521_0038 deb5e92b057427700d861a408413b529 125 PRINTS PR01650 Bacterial translocase SecE signature 87 107 3.9E-12 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 D521_0038 deb5e92b057427700d861a408413b529 125 Gene3D G3DSA:1.20.5.1030 64 122 2.5E-16 T 14-10-2018 IPR038379 SecE superfamily D521_0038 deb5e92b057427700d861a408413b529 125 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 68 117 6.9E-19 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 D521_0038 deb5e92b057427700d861a408413b529 125 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 67 121 1.2E-17 T 14-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 D521_0038 deb5e92b057427700d861a408413b529 125 Hamap MF_00422 Protein translocase subunit SecE [secE]. 64 119 11.106 T 14-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 Pfam PF04607 Region found in RelA / SpoT proteins 290 399 1.7E-33 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 Pfam PF13291 ACT domain 699 777 2.5E-18 T 14-10-2018 IPR002912 ACT domain D521_0721 47acf18d331a76a12491d6b431e08b0c 781 SUPERFAMILY SSF81271 430 503 1.24E-20 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 SMART SM00471 96 208 7.3E-9 T 14-10-2018 IPR003607 HD/PDEase domain D521_0721 47acf18d331a76a12491d6b431e08b0c 781 Gene3D G3DSA:3.30.70.260 700 780 8.2E-11 T 14-10-2018 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 SUPERFAMILY SSF109604 66 244 4.08E-68 T 14-10-2018 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 SUPERFAMILY SSF81301 236 447 4.09E-59 T 14-10-2018 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 81 777 1.5E-224 T 14-10-2018 IPR004811 RelA/SpoT family GO:0015969 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 Gene3D G3DSA:1.10.3210.10 60 245 2.7E-75 T 14-10-2018 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 Pfam PF02824 TGS domain 443 502 1.1E-18 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 Gene3D G3DSA:3.10.20.30 436 509 5.7E-29 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_0721 47acf18d331a76a12491d6b431e08b0c 781 SMART SM00954 290 400 5.1E-62 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 Pfam PF13328 HD domain 81 230 2.3E-47 T 14-10-2018 IPR003607 HD/PDEase domain D521_0721 47acf18d331a76a12491d6b431e08b0c 781 SUPERFAMILY SSF55021 714 778 1.42E-5 T 14-10-2018 D521_0721 47acf18d331a76a12491d6b431e08b0c 781 Gene3D G3DSA:3.30.460.10 248 379 2.5E-44 T 14-10-2018 D521_0906 1e7a82172450eb17a48f824899dd00d5 731 Pfam PF02310 B12 binding domain 601 710 1.4E-16 T 14-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 D521_0906 1e7a82172450eb17a48f824899dd00d5 731 Pfam PF01642 Methylmalonyl-CoA mutase 46 559 9.0E-241 T 14-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 D521_0906 1e7a82172450eb17a48f824899dd00d5 731 SUPERFAMILY SSF52242 566 727 9.55E-57 T 14-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 D521_0906 1e7a82172450eb17a48f824899dd00d5 731 Gene3D G3DSA:3.40.50.280 565 728 6.1E-53 T 14-10-2018 D521_0906 1e7a82172450eb17a48f824899dd00d5 731 SUPERFAMILY SSF51703 18 561 4.71E-225 T 14-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 D521_0906 1e7a82172450eb17a48f824899dd00d5 731 Gene3D G3DSA:3.20.20.240 45 561 3.1E-243 T 14-10-2018 D521_0906 1e7a82172450eb17a48f824899dd00d5 731 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 598 727 1.7E-60 T 14-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 D521_0906 1e7a82172450eb17a48f824899dd00d5 731 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 45 566 6.8E-268 T 14-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 D521_0229 545aa6cba8684a4ebbad48e3fafa6240 253 Pfam PF04452 RNA methyltransferase 18 240 1.8E-58 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 D521_0229 545aa6cba8684a4ebbad48e3fafa6240 253 SUPERFAMILY SSF88697 1 65 8.7E-10 T 14-10-2018 IPR015947 PUA-like superfamily D521_0229 545aa6cba8684a4ebbad48e3fafa6240 253 Gene3D G3DSA:3.40.1280.10 72 252 3.3E-54 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal D521_0229 545aa6cba8684a4ebbad48e3fafa6240 253 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 4 242 1.2E-48 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 D521_0229 545aa6cba8684a4ebbad48e3fafa6240 253 SUPERFAMILY SSF75217 72 245 1.61E-43 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases D521_0229 545aa6cba8684a4ebbad48e3fafa6240 253 Gene3D G3DSA:2.40.240.20 1 68 8.5E-12 T 14-10-2018 D521_0229 545aa6cba8684a4ebbad48e3fafa6240 253 PIRSF PIRSF015601 1 244 4.3E-51 T 14-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 D521_0058 3d0ba6b95efbfc36782f81d141781035 273 SMART SM00322 60 125 1.9E-8 T 14-10-2018 IPR004087 K Homology domain GO:0003676 D521_0058 3d0ba6b95efbfc36782f81d141781035 273 Gene3D G3DSA:3.30.1140.32 108 208 1.6E-44 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0058 3d0ba6b95efbfc36782f81d141781035 273 Gene3D G3DSA:3.30.300.20 17 107 1.2E-28 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta D521_0058 3d0ba6b95efbfc36782f81d141781035 273 Pfam PF07650 KH domain 39 110 6.2E-21 T 14-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0058 3d0ba6b95efbfc36782f81d141781035 273 SUPERFAMILY SSF54821 108 206 6.28E-39 T 14-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0058 3d0ba6b95efbfc36782f81d141781035 273 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 202 2.0E-40 T 14-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0058 3d0ba6b95efbfc36782f81d141781035 273 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 1.1E-92 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 D521_0058 3d0ba6b95efbfc36782f81d141781035 273 SUPERFAMILY SSF54814 2 106 3.4E-37 T 14-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 D521_0058 3d0ba6b95efbfc36782f81d141781035 273 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 14-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0058 3d0ba6b95efbfc36782f81d141781035 273 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 38.757 T 14-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 D521_0536 a00514d283c57e4c5dc4b48bd1597c4f 780 SUPERFAMILY SSF90123 173 494 3.4E-76 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 D521_0536 a00514d283c57e4c5dc4b48bd1597c4f 780 SUPERFAMILY SSF52540 500 742 1.41E-91 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0536 a00514d283c57e4c5dc4b48bd1597c4f 780 ProSitePatterns PS00211 ABC transporters family signature. 644 658 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0536 a00514d283c57e4c5dc4b48bd1597c4f 780 SMART SM00382 532 718 2.5E-19 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0536 a00514d283c57e4c5dc4b48bd1597c4f 780 Pfam PF00005 ABC transporter 524 672 9.4E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0536 a00514d283c57e4c5dc4b48bd1597c4f 780 Pfam PF00664 ABC transporter transmembrane region 185 456 3.0E-41 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 D521_0536 a00514d283c57e4c5dc4b48bd1597c4f 780 Gene3D G3DSA:3.40.50.300 504 752 1.1E-93 T 14-10-2018 D521_0536 a00514d283c57e4c5dc4b48bd1597c4f 780 Gene3D G3DSA:1.20.1560.10 153 494 1.3E-85 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 D521_0916 27d666016b29f52b409b5d74f9a8fb31 290 Pfam PF13525 Outer membrane lipoprotein 56 259 3.5E-60 T 14-10-2018 IPR039565 Outer membrane lipoprotein BamD-like D521_0916 27d666016b29f52b409b5d74f9a8fb31 290 SUPERFAMILY SSF48452 59 255 8.86E-7 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0916 27d666016b29f52b409b5d74f9a8fb31 290 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 24 266 36.108 T 14-10-2018 IPR017689 Outer membrane protein assembly factor BamD D521_0916 27d666016b29f52b409b5d74f9a8fb31 290 Gene3D G3DSA:1.25.40.10 55 276 6.9E-53 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0916 27d666016b29f52b409b5d74f9a8fb31 290 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 27 271 1.3E-79 T 14-10-2018 IPR017689 Outer membrane protein assembly factor BamD D521_1883 7dfd6fc0ae7be5f3e2cbddd53d5c9648 352 SUPERFAMILY SSF51556 7 351 2.64E-139 T 14-10-2018 IPR032466 Metal-dependent hydrolase D521_1883 7dfd6fc0ae7be5f3e2cbddd53d5c9648 352 PIRSF PIRSF001237 4 352 7.6E-137 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_1883 7dfd6fc0ae7be5f3e2cbddd53d5c9648 352 Gene3D G3DSA:3.20.20.140 7 352 3.5E-105 T 14-10-2018 D521_1883 7dfd6fc0ae7be5f3e2cbddd53d5c9648 352 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 8 351 3.7E-142 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_1883 7dfd6fc0ae7be5f3e2cbddd53d5c9648 352 Pfam PF01979 Amidohydrolase family 15 324 3.6E-20 T 14-10-2018 IPR006680 Amidohydrolase-related GO:0016787 D521_1883 7dfd6fc0ae7be5f3e2cbddd53d5c9648 352 ProSitePatterns PS00482 Dihydroorotase signature 1. 15 23 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_1883 7dfd6fc0ae7be5f3e2cbddd53d5c9648 352 Hamap MF_00219 Dihydroorotase [pyrC]. 6 352 46.146 T 14-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_1883 7dfd6fc0ae7be5f3e2cbddd53d5c9648 352 ProSitePatterns PS00483 Dihydroorotase signature 2. 254 265 - T 14-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0999 f285ee687d90c5b16b557a0a9db55d34 224 SUPERFAMILY SSF51366 11 216 1.07E-55 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 D521_0999 f285ee687d90c5b16b557a0a9db55d34 224 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 13 213 3.4E-40 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 D521_0999 f285ee687d90c5b16b557a0a9db55d34 224 Gene3D G3DSA:3.20.20.70 9 222 2.0E-62 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0999 f285ee687d90c5b16b557a0a9db55d34 224 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 11 218 38.339 T 14-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 D521_0830 7dcff5d8e9da5138e93956150085d8a6 556 Pfam PF13450 NAD(P)-binding Rossmann-like domain 22 67 3.5E-6 T 14-10-2018 D521_0830 7dcff5d8e9da5138e93956150085d8a6 556 SUPERFAMILY SSF51905 14 455 1.85E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0830 7dcff5d8e9da5138e93956150085d8a6 556 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 453 553 4.8E-50 T 14-10-2018 D521_0830 7dcff5d8e9da5138e93956150085d8a6 556 Gene3D G3DSA:3.30.9.90 89 457 4.0E-197 T 14-10-2018 D521_0830 7dcff5d8e9da5138e93956150085d8a6 556 Gene3D G3DSA:3.50.50.60 18 394 4.0E-197 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0830 7dcff5d8e9da5138e93956150085d8a6 556 SUPERFAMILY SSF54373 221 315 6.28E-36 T 14-10-2018 D521_0830 7dcff5d8e9da5138e93956150085d8a6 556 Gene3D G3DSA:3.30.70.20 458 551 3.9E-39 T 14-10-2018 D521_0830 7dcff5d8e9da5138e93956150085d8a6 556 SUPERFAMILY SSF54862 457 554 3.53E-28 T 14-10-2018 D521_0815 36b6d07cc7be5d53b2f6324b5af4187b 125 Pfam PF02627 Carboxymuconolactone decarboxylase family 36 118 1.0E-23 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 D521_0815 36b6d07cc7be5d53b2f6324b5af4187b 125 Gene3D G3DSA:1.20.1290.10 3 124 7.5E-39 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 D521_0815 36b6d07cc7be5d53b2f6324b5af4187b 125 SUPERFAMILY SSF69118 3 125 1.35E-37 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 SMART SM00562 3 140 1.0E-78 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 14-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 Gene3D G3DSA:3.30.70.141 1 141 2.2E-57 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 33.786 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 SUPERFAMILY SSF54919 1 139 5.89E-55 T 14-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 2.2E-36 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 2.2E-36 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 2.2E-36 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 2.2E-36 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 2.2E-36 T 14-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_1078 599f2e944c3a4827ee49b15a77d49b9d 141 Pfam PF00334 Nucleoside diphosphate kinase 4 135 8.3E-53 T 14-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_0320 97cb57839082c0619cb8a90ebd7ec7e0 347 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 332 1.5E-76 T 14-10-2018 IPR016040 NAD(P)-binding domain D521_0320 97cb57839082c0619cb8a90ebd7ec7e0 347 Gene3D G3DSA:3.40.50.720 6 330 5.9E-103 T 14-10-2018 D521_0320 97cb57839082c0619cb8a90ebd7ec7e0 347 SUPERFAMILY SSF51735 2 337 1.17E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0320 97cb57839082c0619cb8a90ebd7ec7e0 347 Gene3D G3DSA:3.90.25.10 189 337 5.9E-103 T 14-10-2018 D521_1853 0735cad92f883040e1e457a97db778a7 452 Pfam PF04055 Radical SAM superfamily 150 324 4.1E-28 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 D521_1853 0735cad92f883040e1e457a97db778a7 452 Pfam PF00919 Uncharacterized protein family UPF0004 3 103 9.2E-30 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 D521_1853 0735cad92f883040e1e457a97db778a7 452 Pfam PF01938 TRAM domain 380 442 2.0E-8 T 14-10-2018 IPR002792 TRAM domain D521_1853 0735cad92f883040e1e457a97db778a7 452 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 440 4.9E-145 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 D521_1853 0735cad92f883040e1e457a97db778a7 452 SMART SM00729 146 367 1.4E-53 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 D521_1853 0735cad92f883040e1e457a97db778a7 452 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 3 442 1.2E-168 T 14-10-2018 D521_1853 0735cad92f883040e1e457a97db778a7 452 Gene3D G3DSA:3.40.50.12160 2 136 6.7E-34 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily D521_1853 0735cad92f883040e1e457a97db778a7 452 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 2 444 70.751 T 14-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 D521_1853 0735cad92f883040e1e457a97db778a7 452 SUPERFAMILY SSF102114 128 372 1.31E-59 T 14-10-2018 D521_1853 0735cad92f883040e1e457a97db778a7 452 Gene3D G3DSA:3.80.30.20 143 381 1.1E-81 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe D521_1853 0735cad92f883040e1e457a97db778a7 452 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 150 170 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 D521_0181 5a2425e84d7ccea51e183cd2f13d913e 286 SUPERFAMILY SSF52540 44 191 4.57E-26 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0181 5a2425e84d7ccea51e183cd2f13d913e 286 Pfam PF05673 Protein of unknown function (DUF815) 28 283 7.4E-105 T 14-10-2018 IPR008533 Domain of unknown function DUF815 D521_0181 5a2425e84d7ccea51e183cd2f13d913e 286 Gene3D G3DSA:3.40.50.300 50 193 5.5E-10 T 14-10-2018 D521_0876 4d203ecf7c71dd3417a3d85124bd6e95 190 SUPERFAMILY SSF53167 26 186 2.23E-23 T 14-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 D521_0876 4d203ecf7c71dd3417a3d85124bd6e95 190 Pfam PF01048 Phosphorylase superfamily 29 69 3.4E-7 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 D521_0876 4d203ecf7c71dd3417a3d85124bd6e95 190 Pfam PF01048 Phosphorylase superfamily 122 173 7.3E-9 T 14-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 D521_0876 4d203ecf7c71dd3417a3d85124bd6e95 190 Gene3D G3DSA:3.40.50.1580 3 190 2.4E-30 T 14-10-2018 D521_0080 3b900038b7754d0d832a01830f351d07 110 SUPERFAMILY SSF54913 8 109 9.64E-34 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta D521_0080 3b900038b7754d0d832a01830f351d07 110 Gene3D G3DSA:3.30.70.120 2 110 9.2E-35 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal D521_0080 3b900038b7754d0d832a01830f351d07 110 Pfam PF03091 CutA1 divalent ion tolerance protein 11 107 4.1E-33 T 14-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 D521_1130 0d7ab3437c8e73895cfc750b3e879976 74 SUPERFAMILY SSF50331 6 73 1.55E-21 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal D521_1130 0d7ab3437c8e73895cfc750b3e879976 74 TIGRFAM TIGR00638 Mop: molybdenum-pterin binding domain 5 73 4.4E-23 T 14-10-2018 IPR004606 Molybdenum-pterin binding GO:0015689 D521_1130 0d7ab3437c8e73895cfc750b3e879976 74 Gene3D G3DSA:2.40.50.100 5 71 1.6E-23 T 14-10-2018 D521_1130 0d7ab3437c8e73895cfc750b3e879976 74 Pfam PF03459 TOBE domain 8 70 8.3E-20 T 14-10-2018 IPR005116 Transport-associated OB, type 1 D521_0764 13121aa7d695cf0fd2d89e98e3a081fa 243 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0764 13121aa7d695cf0fd2d89e98e3a081fa 243 SUPERFAMILY SSF52540 3 229 6.25E-71 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0764 13121aa7d695cf0fd2d89e98e3a081fa 243 Gene3D G3DSA:3.40.50.300 3 238 4.2E-72 T 14-10-2018 D521_0764 13121aa7d695cf0fd2d89e98e3a081fa 243 SMART SM00382 28 215 2.3E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0764 13121aa7d695cf0fd2d89e98e3a081fa 243 Pfam PF00005 ABC transporter 19 167 1.8E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0582 55b6e34a19de7a2a906b13a4927a8f8c 310 Gene3D G3DSA:2.120.10.30 37 310 3.8E-64 T 14-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like D521_0582 55b6e34a19de7a2a906b13a4927a8f8c 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 271 289 4.1E-5 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) D521_0582 55b6e34a19de7a2a906b13a4927a8f8c 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 227 244 4.1E-5 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) D521_0582 55b6e34a19de7a2a906b13a4927a8f8c 310 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 165 187 4.1E-5 T 14-10-2018 IPR005511 Senescence marker protein-30 (SMP-30) D521_0582 55b6e34a19de7a2a906b13a4927a8f8c 310 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 48 287 2.0E-37 T 14-10-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region D521_0582 55b6e34a19de7a2a906b13a4927a8f8c 310 SUPERFAMILY SSF63829 46 305 3.92E-52 T 14-10-2018 D521_1248 cfe7e7bca201aed1f6f2a8e67936a17b 400 Pfam PF02684 Lipid-A-disaccharide synthetase 6 376 8.9E-88 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 D521_1248 cfe7e7bca201aed1f6f2a8e67936a17b 400 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 5 386 3.6E-90 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 D521_1248 cfe7e7bca201aed1f6f2a8e67936a17b 400 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 1 392 35.808 T 14-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 D521_1248 cfe7e7bca201aed1f6f2a8e67936a17b 400 SUPERFAMILY SSF53756 3 366 2.51E-25 T 14-10-2018 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 Pfam PF12631 MnmE helical domain 127 457 4.8E-58 T 14-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 Pfam PF01926 50S ribosome-binding GTPase 223 311 4.7E-21 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 PRINTS PR00449 Transforming protein P21 ras signature 333 346 1.4E-5 T 14-10-2018 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 PRINTS PR00449 Transforming protein P21 ras signature 221 242 1.4E-5 T 14-10-2018 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 Pfam PF10396 GTP-binding protein TrmE N-terminus 7 124 3.3E-33 T 14-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 Gene3D G3DSA:3.30.1360.120 1 125 3.2E-36 T 14-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 Gene3D G3DSA:1.20.120.430 126 460 6.2E-100 T 14-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 6 460 31.718 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 SUPERFAMILY SSF52540 73 378 4.04E-46 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 221 373 5.3E-20 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 12 460 4.8E-101 T 14-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 D521_2115 8e3eef1162e4ae547614750c21aa41a4 460 Gene3D G3DSA:3.40.50.300 221 387 6.2E-100 T 14-10-2018 D521_0996 8c3de39214f51d741d0c233a7b3c4718 239 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 227 30.232 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0996 8c3de39214f51d741d0c233a7b3c4718 239 Gene3D G3DSA:3.90.226.10 1 232 6.0E-67 T 14-10-2018 D521_0996 8c3de39214f51d741d0c233a7b3c4718 239 Pfam PF01039 Carboxyl transferase domain 61 187 2.7E-12 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 D521_0996 8c3de39214f51d741d0c233a7b3c4718 239 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 197 206 2.9E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0996 8c3de39214f51d741d0c233a7b3c4718 239 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 146 163 2.9E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0996 8c3de39214f51d741d0c233a7b3c4718 239 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 75 89 2.9E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0996 8c3de39214f51d741d0c233a7b3c4718 239 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 175 186 2.9E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0996 8c3de39214f51d741d0c233a7b3c4718 239 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 109 127 2.9E-37 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0996 8c3de39214f51d741d0c233a7b3c4718 239 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 229 3.9E-100 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0996 8c3de39214f51d741d0c233a7b3c4718 239 SUPERFAMILY SSF52096 2 227 4.97E-70 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_0396 89f63d9f58463fee31a258dbbae26ee2 244 Gene3D G3DSA:3.40.50.1000 11 212 4.7E-78 T 14-10-2018 IPR023214 HAD superfamily D521_0396 89f63d9f58463fee31a258dbbae26ee2 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 190 203 2.9E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_0396 89f63d9f58463fee31a258dbbae26ee2 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 161 2.9E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_0396 89f63d9f58463fee31a258dbbae26ee2 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 163 183 2.9E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_0396 89f63d9f58463fee31a258dbbae26ee2 244 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 10 21 2.9E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_0396 89f63d9f58463fee31a258dbbae26ee2 244 SUPERFAMILY SSF56784 9 236 7.47E-36 T 14-10-2018 IPR036412 HAD-like superfamily D521_0396 89f63d9f58463fee31a258dbbae26ee2 244 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 13 192 4.7E-18 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_0396 89f63d9f58463fee31a258dbbae26ee2 244 Gene3D G3DSA:1.10.150.240 37 103 4.7E-78 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 D521_0396 89f63d9f58463fee31a258dbbae26ee2 244 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 11 205 1.3E-50 T 14-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 D521_0396 89f63d9f58463fee31a258dbbae26ee2 244 Pfam PF13419 Haloacid dehalogenase-like hydrolase 90 200 2.7E-10 T 14-10-2018 D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 Gene3D G3DSA:1.10.560.10 8 521 1.5E-236 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 526 6.7E-252 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 SUPERFAMILY SSF54849 137 203 5.49E-25 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 5.2E-98 T 14-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 14-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 Gene3D G3DSA:3.50.7.10 173 379 1.5E-236 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 SUPERFAMILY SSF52029 184 376 1.5E-83 T 14-10-2018 IPR027409 GroEL-like apical domain superfamily D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 PRINTS PR00298 60kDa chaperonin signature 398 419 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 PRINTS PR00298 60kDa chaperonin signature 27 53 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 PRINTS PR00298 60kDa chaperonin signature 350 375 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 PRINTS PR00298 60kDa chaperonin signature 83 110 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 PRINTS PR00298 60kDa chaperonin signature 268 291 8.2E-75 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 SUPERFAMILY SSF48592 7 521 7.25E-77 T 14-10-2018 IPR027413 GroEL-like equatorial domain superfamily D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 Gene3D G3DSA:3.30.260.10 138 410 1.5E-236 T 14-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily D521_1784 d590abde41a8e891e16e1b49d9ca96d8 550 Hamap MF_00600 60 kDa chaperonin [groL]. 2 549 41.286 T 14-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 D521_0309 10395c2ed91a8067fdc523a2f7c71504 376 SUPERFAMILY SSF51735 6 355 2.24E-87 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0309 10395c2ed91a8067fdc523a2f7c71504 376 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 6 356 2.5E-176 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 D521_0309 10395c2ed91a8067fdc523a2f7c71504 376 Gene3D G3DSA:3.40.50.720 8 340 3.6E-164 T 14-10-2018 D521_0309 10395c2ed91a8067fdc523a2f7c71504 376 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 6 359 55.34 T 14-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 D521_0309 10395c2ed91a8067fdc523a2f7c71504 376 Pfam PF16363 GDP-mannose 4,6 dehydratase 9 349 2.0E-156 T 14-10-2018 IPR016040 NAD(P)-binding domain D521_0309 10395c2ed91a8067fdc523a2f7c71504 376 Gene3D G3DSA:3.90.25.10 196 354 3.6E-164 T 14-10-2018 D521_0061 ad8fe934a23371dcb0e890fec74371d0 89 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 9 79 1.6E-34 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0061 ad8fe934a23371dcb0e890fec74371d0 89 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 9 79 3.0E-27 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0061 ad8fe934a23371dcb0e890fec74371d0 89 PRINTS PR00973 Ribosomal protein S17 family signature 70 77 7.1E-11 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0061 ad8fe934a23371dcb0e890fec74371d0 89 PRINTS PR00973 Ribosomal protein S17 family signature 28 51 7.1E-11 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0061 ad8fe934a23371dcb0e890fec74371d0 89 PRINTS PR00973 Ribosomal protein S17 family signature 60 70 7.1E-11 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0061 ad8fe934a23371dcb0e890fec74371d0 89 Pfam PF00366 Ribosomal protein S17 14 80 1.2E-30 T 14-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0061 ad8fe934a23371dcb0e890fec74371d0 89 ProSitePatterns PS00056 Ribosomal protein S17 signature. 60 72 - T 14-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0061 ad8fe934a23371dcb0e890fec74371d0 89 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 9 84 23.718 T 14-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0061 ad8fe934a23371dcb0e890fec74371d0 89 Gene3D G3DSA:2.40.50.140 6 87 2.6E-33 T 14-10-2018 D521_0061 ad8fe934a23371dcb0e890fec74371d0 89 SUPERFAMILY SSF50249 9 85 6.85E-30 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1524 335aa327fafb0f6323874e16be5a59c2 442 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 314 441 3.1E-22 T 14-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain D521_1524 335aa327fafb0f6323874e16be5a59c2 442 SUPERFAMILY SSF54862 57 323 4.86E-31 T 14-10-2018 D521_1524 335aa327fafb0f6323874e16be5a59c2 442 Pfam PF12801 4Fe-4S binding domain 48 89 1.0E-11 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1524 335aa327fafb0f6323874e16be5a59c2 442 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 3 428 4.0E-147 T 14-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 D521_1524 335aa327fafb0f6323874e16be5a59c2 442 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 226 237 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1524 335aa327fafb0f6323874e16be5a59c2 442 Pfam PF13746 4Fe-4S dicluster domain 173 278 2.4E-43 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1524 335aa327fafb0f6323874e16be5a59c2 442 Gene3D G3DSA:2.60.40.10 315 440 7.0E-18 T 14-10-2018 IPR013783 Immunoglobulin-like fold D521_0114 80880ac7f3e775cc14c2e96705c8f379 118 Pfam PF01230 HIT domain 14 112 7.8E-26 T 14-10-2018 IPR001310 Histidine triad (HIT) protein D521_0114 80880ac7f3e775cc14c2e96705c8f379 118 PRINTS PR00332 Histidine triad family signature 8 24 6.0E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein D521_0114 80880ac7f3e775cc14c2e96705c8f379 118 PRINTS PR00332 Histidine triad family signature 100 110 6.0E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein D521_0114 80880ac7f3e775cc14c2e96705c8f379 118 PRINTS PR00332 Histidine triad family signature 29 47 6.0E-19 T 14-10-2018 IPR001310 Histidine triad (HIT) protein D521_0114 80880ac7f3e775cc14c2e96705c8f379 118 SUPERFAMILY SSF54197 4 114 6.52E-35 T 14-10-2018 IPR036265 HIT-like superfamily D521_0114 80880ac7f3e775cc14c2e96705c8f379 118 ProSitePatterns PS00892 HIT domain signature. 93 111 - T 14-10-2018 IPR019808 Histidine triad, conserved site D521_0114 80880ac7f3e775cc14c2e96705c8f379 118 Gene3D G3DSA:3.30.428.10 1 116 8.7E-39 T 14-10-2018 IPR036265 HIT-like superfamily D521_1243 33c34177464c3cdb380fd71be1e7f808 245 SUPERFAMILY SSF55781 58 236 7.19E-31 T 14-10-2018 D521_1243 33c34177464c3cdb380fd71be1e7f808 245 SMART SM00346 1 82 5.3E-13 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 D521_1243 33c34177464c3cdb380fd71be1e7f808 245 Gene3D G3DSA:3.30.450.40 65 235 2.8E-30 T 14-10-2018 IPR029016 GAF-like domain superfamily D521_1243 33c34177464c3cdb380fd71be1e7f808 245 Gene3D G3DSA:1.10.10.10 1 60 4.3E-14 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1243 33c34177464c3cdb380fd71be1e7f808 245 Pfam PF01614 Bacterial transcriptional regulator 115 235 3.7E-12 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal D521_1243 33c34177464c3cdb380fd71be1e7f808 245 SUPERFAMILY SSF46785 1 64 1.87E-9 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1243 33c34177464c3cdb380fd71be1e7f808 245 Pfam PF09339 IclR helix-turn-helix domain 1 43 2.7E-11 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 D521_0079 dac753fdcfe1cec7effc1be65e3ce29a 130 SUPERFAMILY SSF64263 1 119 6.28E-50 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0079 dac753fdcfe1cec7effc1be65e3ce29a 130 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 117 3.4E-45 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0079 dac753fdcfe1cec7effc1be65e3ce29a 130 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0079 dac753fdcfe1cec7effc1be65e3ce29a 130 Pfam PF01196 Ribosomal protein L17 20 116 1.4E-34 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0079 dac753fdcfe1cec7effc1be65e3ce29a 130 Gene3D G3DSA:3.90.1030.10 1 116 2.0E-46 T 14-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0079 dac753fdcfe1cec7effc1be65e3ce29a 130 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 26.625 T 14-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0222 b7ddecad25bdce9ee07ecae27bda2406 281 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 21 259 2.2E-27 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0222 b7ddecad25bdce9ee07ecae27bda2406 281 Gene3D G3DSA:3.20.20.70 5 278 5.6E-96 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0222 b7ddecad25bdce9ee07ecae27bda2406 281 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 8 264 8.2E-68 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0222 b7ddecad25bdce9ee07ecae27bda2406 281 SUPERFAMILY SSF51366 8 266 7.25E-72 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 D521_0222 b7ddecad25bdce9ee07ecae27bda2406 281 SMART SM00934 22 264 3.7E-44 T 14-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0222 b7ddecad25bdce9ee07ecae27bda2406 281 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 95 108 - T 14-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0222 b7ddecad25bdce9ee07ecae27bda2406 281 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 7 277 34.975 T 14-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 Gene3D G3DSA:3.40.50.10950 452 767 1.2E-89 T 14-10-2018 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 Gene3D G3DSA:3.40.50.10750 586 740 1.2E-89 T 14-10-2018 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 Pfam PF01515 Phosphate acetyl/butaryl transferase 447 763 1.7E-92 T 14-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 Pfam PF00390 Malic enzyme, N-terminal domain 125 162 3.2E-5 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 Pfam PF00390 Malic enzyme, N-terminal domain 30 124 1.3E-22 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 Pfam PF03949 Malic enzyme, NAD binding domain 176 371 7.2E-21 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 SUPERFAMILY SSF51735 174 466 1.29E-83 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 PIRSF PIRSF036684 9 772 0.0 T 14-10-2018 IPR012188 NAD(P)-dependent malic enzyme GO:0004470|GO:0006108|GO:0046872 KEGG: 00620+1.1.1.40|KEGG: 00710+1.1.1.40|MetaCyc: PWY-241|MetaCyc: PWY-7117 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 ProSitePatterns PS00331 Malic enzymes signature. 170 186 - T 14-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 Pfam PF12434 Malate dehydrogenase enzyme 8 27 2.4E-8 T 14-10-2018 IPR032683 Malate dehydrogenase enzyme, N-terminal D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 SUPERFAMILY SSF53659 440 767 1.93E-84 T 14-10-2018 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 SMART SM01274 29 162 9.8E-81 T 14-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 Gene3D G3DSA:3.40.50.720 172 451 1.2E-79 T 14-10-2018 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 Gene3D G3DSA:3.40.50.10380 6 171 2.3E-70 T 14-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 SUPERFAMILY SSF53223 21 172 1.15E-53 T 14-10-2018 D521_0227 658ac65fa6a5e26d1154a05ba576151b 775 SMART SM00919 174 411 1.2E-132 T 14-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 D521_0264 95ea025600b0ed63feb462a7ae507a90 383 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 9 200 4.2E-82 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0264 95ea025600b0ed63feb462a7ae507a90 383 SUPERFAMILY SSF55821 4 205 3.43E-86 T 14-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily D521_0264 95ea025600b0ed63feb462a7ae507a90 383 Gene3D G3DSA:3.90.870.10 1 207 6.4E-86 T 14-10-2018 D521_0264 95ea025600b0ed63feb462a7ae507a90 383 SUPERFAMILY SSF142695 207 375 1.31E-40 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 D521_0264 95ea025600b0ed63feb462a7ae507a90 383 Pfam PF00925 GTP cyclohydrolase II 213 373 1.1E-30 T 14-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 D521_0264 95ea025600b0ed63feb462a7ae507a90 383 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 8 201 6.4E-73 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0264 95ea025600b0ed63feb462a7ae507a90 383 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 3 205 37.893 T 14-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0264 95ea025600b0ed63feb462a7ae507a90 383 PIRSF PIRSF001259 3 382 7.7E-118 T 14-10-2018 D521_0264 95ea025600b0ed63feb462a7ae507a90 383 Gene3D G3DSA:3.40.50.10990 208 376 1.2E-19 T 14-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 Pfam PF05231 MASE1 30 266 1.6E-21 T 14-10-2018 IPR007895 MASE1 D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 Gene3D G3DSA:3.20.20.450 742 990 8.1E-91 T 14-10-2018 IPR035919 EAL domain superfamily D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 SUPERFAMILY SSF55785 308 425 2.27E-7 T 14-10-2018 IPR035965 PAS domain superfamily D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 SUPERFAMILY SSF55785 432 546 5.58E-15 T 14-10-2018 IPR035965 PAS domain superfamily D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 Gene3D G3DSA:3.30.450.20 444 567 2.9E-15 T 14-10-2018 D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 SMART SM00052 740 985 1.3E-99 T 14-10-2018 IPR001633 EAL domain D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 Gene3D G3DSA:3.30.70.270 568 741 6.5E-60 T 14-10-2018 D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 SMART SM00091 444 510 0.0052 T 14-10-2018 IPR000014 PAS domain D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 SMART SM00091 319 388 61.0 T 14-10-2018 IPR000014 PAS domain D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 566 729 3.5E-46 T 14-10-2018 IPR000160 GGDEF domain D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 Pfam PF00563 EAL domain 746 980 2.0E-71 T 14-10-2018 IPR001633 EAL domain D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 SUPERFAMILY SSF55073 574 731 1.88E-50 T 14-10-2018 IPR029787 Nucleotide cyclase D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 Pfam PF13426 PAS domain 331 386 0.3 T 14-10-2018 IPR000014 PAS domain D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 Pfam PF13426 PAS domain 457 543 3.0E-6 T 14-10-2018 IPR000014 PAS domain D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 SUPERFAMILY SSF141868 747 989 2.48E-83 T 14-10-2018 IPR035919 EAL domain superfamily D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 Pfam PF00990 Diguanylate cyclase, GGDEF domain 569 725 6.8E-52 T 14-10-2018 IPR000160 GGDEF domain D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 SMART SM00267 558 730 2.2E-70 T 14-10-2018 IPR000160 GGDEF domain D521_0649 5e6cb91532c6099c9ad241b498b44cdf 990 Gene3D G3DSA:3.30.450.20 310 434 2.6E-11 T 14-10-2018 D521_1153 32d43c98955f7f1bfbd4975995cb2f88 302 Pfam PF00892 EamA-like transporter family 8 141 5.6E-22 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 D521_1153 32d43c98955f7f1bfbd4975995cb2f88 302 Pfam PF00892 EamA-like transporter family 155 296 2.9E-11 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 D521_1153 32d43c98955f7f1bfbd4975995cb2f88 302 SUPERFAMILY SSF103481 42 143 2.75E-14 T 14-10-2018 D521_1153 32d43c98955f7f1bfbd4975995cb2f88 302 SUPERFAMILY SSF103481 225 297 3.01E-7 T 14-10-2018 D521_0095 259fa64a08ab52fe4c3a86ebc07ea94c 288 Pfam PF00005 ABC transporter 42 191 1.0E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0095 259fa64a08ab52fe4c3a86ebc07ea94c 288 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0095 259fa64a08ab52fe4c3a86ebc07ea94c 288 Gene3D G3DSA:3.40.50.300 22 272 3.1E-67 T 14-10-2018 D521_0095 259fa64a08ab52fe4c3a86ebc07ea94c 288 SMART SM00382 51 248 3.9E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0095 259fa64a08ab52fe4c3a86ebc07ea94c 288 SUPERFAMILY SSF52540 25 254 8.57E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1732 df3c506dc77d8095691ea9b562b2bc10 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 14-10-2018 IPR019844 Cold-shock conserved site D521_1732 df3c506dc77d8095691ea9b562b2bc10 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 9.6E-30 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 D521_1732 df3c506dc77d8095691ea9b562b2bc10 67 SMART SM00357 3 67 4.1E-28 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 D521_1732 df3c506dc77d8095691ea9b562b2bc10 67 PIRSF PIRSF002599 1 67 9.2E-24 T 14-10-2018 IPR012156 Cold shock, CspA GO:0003676 D521_1732 df3c506dc77d8095691ea9b562b2bc10 67 SUPERFAMILY SSF50249 1 65 9.64E-25 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1732 df3c506dc77d8095691ea9b562b2bc10 67 Gene3D G3DSA:2.40.50.140 1 67 1.9E-29 T 14-10-2018 D521_1732 df3c506dc77d8095691ea9b562b2bc10 67 PRINTS PR00050 Cold shock protein signature 40 58 1.7E-15 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 D521_1732 df3c506dc77d8095691ea9b562b2bc10 67 PRINTS PR00050 Cold shock protein signature 25 34 1.7E-15 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 D521_1732 df3c506dc77d8095691ea9b562b2bc10 67 PRINTS PR00050 Cold shock protein signature 4 19 1.7E-15 T 14-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 D521_1390 5d371f4a71e0dc9f01b2aef00fd0deae 289 Pfam PF02911 Formyl transferase, C-terminal domain 202 281 4.3E-12 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_1390 5d371f4a71e0dc9f01b2aef00fd0deae 289 SUPERFAMILY SSF50486 201 248 3.45E-14 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 D521_1390 5d371f4a71e0dc9f01b2aef00fd0deae 289 Gene3D G3DSA:3.40.50.12230 1 286 4.7E-85 T 14-10-2018 D521_1390 5d371f4a71e0dc9f01b2aef00fd0deae 289 Pfam PF00551 Formyl transferase 25 176 4.0E-27 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_1390 5d371f4a71e0dc9f01b2aef00fd0deae 289 SUPERFAMILY SSF53328 2 202 3.53E-51 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_0392 80cf0e60d5562d5ebd6ee67e3557c085 448 Gene3D G3DSA:2.40.50.100 142 291 6.7E-72 T 14-10-2018 D521_0392 80cf0e60d5562d5ebd6ee67e3557c085 448 Gene3D G3DSA:2.40.420.20 124 429 6.7E-72 T 14-10-2018 D521_0392 80cf0e60d5562d5ebd6ee67e3557c085 448 Gene3D G3DSA:2.40.30.170 128 371 6.7E-72 T 14-10-2018 D521_0392 80cf0e60d5562d5ebd6ee67e3557c085 448 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 126 365 2.1E-56 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain D521_0392 80cf0e60d5562d5ebd6ee67e3557c085 448 Gene3D G3DSA:1.10.287.470 176 249 6.7E-72 T 14-10-2018 D521_0392 80cf0e60d5562d5ebd6ee67e3557c085 448 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 144 439 4.0E-45 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 D521_0392 80cf0e60d5562d5ebd6ee67e3557c085 448 SUPERFAMILY SSF111369 144 369 5.23E-20 T 14-10-2018 D521_0123 3235916270ac72e56884cf7c280363da 257 Pfam PF02167 Cytochrome C1 family 45 255 1.6E-18 T 14-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 D521_0123 3235916270ac72e56884cf7c280363da 257 Gene3D G3DSA:1.10.760.10 28 222 6.2E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0123 3235916270ac72e56884cf7c280363da 257 SUPERFAMILY SSF46626 29 221 1.43E-48 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0068 44e3647b3226ba7ccd52ac5a1aeb9dc6 117 SUPERFAMILY SSF53137 3 115 8.07E-48 T 14-10-2018 D521_0068 44e3647b3226ba7ccd52ac5a1aeb9dc6 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 24.603 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0068 44e3647b3226ba7ccd52ac5a1aeb9dc6 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 5 117 1.6E-37 T 14-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0068 44e3647b3226ba7ccd52ac5a1aeb9dc6 117 Gene3D G3DSA:3.30.420.100 1 117 2.4E-39 T 14-10-2018 D521_0068 44e3647b3226ba7ccd52ac5a1aeb9dc6 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 2 117 5.7E-37 T 14-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0699 600918bf0dd63cd13eecb452b0f58b1e 285 SUPERFAMILY SSF54675 7 111 4.71E-26 T 14-10-2018 D521_0699 600918bf0dd63cd13eecb452b0f58b1e 285 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 24 111 1.1E-21 T 14-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 D521_0699 600918bf0dd63cd13eecb452b0f58b1e 285 SUPERFAMILY SSF51690 114 283 3.06E-51 T 14-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 D521_0699 600918bf0dd63cd13eecb452b0f58b1e 285 PIRSF PIRSF006250 6 285 1.1E-82 T 14-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 D521_0699 600918bf0dd63cd13eecb452b0f58b1e 285 Gene3D G3DSA:3.20.20.70 122 273 8.5E-98 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0699 600918bf0dd63cd13eecb452b0f58b1e 285 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 16 283 7.8E-80 T 14-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 D521_0699 600918bf0dd63cd13eecb452b0f58b1e 285 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 114 282 5.2E-48 T 14-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 D521_0699 600918bf0dd63cd13eecb452b0f58b1e 285 Gene3D G3DSA:3.90.1170.20 12 282 8.5E-98 T 14-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 13 409 46.842 T 14-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 Gene3D G3DSA:3.40.50.620 14 233 4.0E-68 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1875 ef306671b61f111b1ca0f195dabe6550 410 SUPERFAMILY SSF55174 312 408 5.23E-18 T 14-10-2018 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 19 408 1.7E-116 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 Pfam PF00579 tRNA synthetases class I (W and Y) 48 329 1.9E-73 T 14-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 67 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 SUPERFAMILY SSF52374 20 327 1.49E-87 T 14-10-2018 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 176 191 1.2E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 226 238 1.2E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 61 83 1.2E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 193 215 1.2E-25 T 14-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 Gene3D G3DSA:3.10.290.10 341 409 4.5E-19 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 D521_1875 ef306671b61f111b1ca0f195dabe6550 410 Gene3D G3DSA:1.10.240.10 234 340 9.4E-31 T 14-10-2018 D521_1103 71c8dfb1fc33a35d740dc137e85e8a08 436 Gene3D G3DSA:2.30.40.20 22 85 1.7E-41 T 14-10-2018 D521_1103 71c8dfb1fc33a35d740dc137e85e8a08 436 Gene3D G3DSA:1.10.150.20 194 246 1.4E-10 T 14-10-2018 D521_1103 71c8dfb1fc33a35d740dc137e85e8a08 436 Pfam PF13438 Domain of unknown function (DUF4113) 387 435 2.0E-22 T 14-10-2018 IPR025188 Domain of unknown function DUF4113 D521_1103 71c8dfb1fc33a35d740dc137e85e8a08 436 Pfam PF00817 impB/mucB/samB family 17 163 7.0E-34 T 14-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 D521_1103 71c8dfb1fc33a35d740dc137e85e8a08 436 Pfam PF11798 IMS family HHH motif 189 214 1.3E-5 T 14-10-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 D521_1103 71c8dfb1fc33a35d740dc137e85e8a08 436 SUPERFAMILY SSF56672 14 251 2.58E-65 T 14-10-2018 D521_1103 71c8dfb1fc33a35d740dc137e85e8a08 436 Gene3D G3DSA:3.30.70.270 16 169 1.7E-41 T 14-10-2018 D521_1103 71c8dfb1fc33a35d740dc137e85e8a08 436 Pfam PF11799 impB/mucB/samB family C-terminal domain 256 373 1.7E-14 T 14-10-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 D521_1798 62e65be28750d5f32bb0e414e1b71ce9 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 205 219 6.5E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1798 62e65be28750d5f32bb0e414e1b71ce9 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 6.5E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1798 62e65be28750d5f32bb0e414e1b71ce9 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 6.5E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1798 62e65be28750d5f32bb0e414e1b71ce9 262 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 6.5E-11 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1798 62e65be28750d5f32bb0e414e1b71ce9 262 Gene3D G3DSA:3.40.50.1820 2 261 1.1E-51 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1798 62e65be28750d5f32bb0e414e1b71ce9 262 Pfam PF00561 alpha/beta hydrolase fold 22 248 3.0E-14 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1798 62e65be28750d5f32bb0e414e1b71ce9 262 SUPERFAMILY SSF53474 2 260 4.05E-52 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0411 3fca113fd8d2234a28019ba636b080d1 172 SUPERFAMILY SSF52540 7 164 5.09E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0411 3fca113fd8d2234a28019ba636b080d1 172 Gene3D G3DSA:3.40.50.300 1 170 1.8E-27 T 14-10-2018 D521_0411 3fca113fd8d2234a28019ba636b080d1 172 Pfam PF13671 AAA domain 10 137 2.9E-9 T 14-10-2018 D521_0434 9a325b441450e287696b7135395987f0 236 Pfam PF00005 ABC transporter 25 176 2.5E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0434 9a325b441450e287696b7135395987f0 236 SUPERFAMILY SSF52540 6 231 9.31E-64 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0434 9a325b441450e287696b7135395987f0 236 Gene3D G3DSA:3.40.50.300 4 235 1.0E-64 T 14-10-2018 D521_0434 9a325b441450e287696b7135395987f0 236 SMART SM00382 34 232 4.6E-15 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0434 9a325b441450e287696b7135395987f0 236 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0018 1acbb7a609d203a9bdcef498f02b57d8 146 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 2 146 1.9E-40 T 14-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 D521_0018 1acbb7a609d203a9bdcef498f02b57d8 146 SUPERFAMILY SSF81573 52 111 1.83E-9 T 14-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily D521_0018 1acbb7a609d203a9bdcef498f02b57d8 146 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 128 10.533 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 D521_0018 1acbb7a609d203a9bdcef498f02b57d8 146 Pfam PF00430 ATP synthase B/B' CF(0) 2 126 3.8E-27 T 14-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 D521_0018 1acbb7a609d203a9bdcef498f02b57d8 146 Gene3D G3DSA:1.20.5.620 52 112 2.3E-6 T 14-10-2018 D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 SUPERFAMILY SSF52540 92 290 2.33E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 Gene3D G3DSA:3.40.50.300 88 284 2.9E-93 T 14-10-2018 D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 SMART SM00962 92 296 6.7E-93 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 SMART SM00963 1 73 2.8E-12 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 17 295 9.3E-92 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 Pfam PF00448 SRP54-type protein, GTPase domain 92 295 3.8E-63 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 Gene3D G3DSA:1.20.120.140 10 293 2.9E-93 T 14-10-2018 D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 16 296 52.628 T 14-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 SMART SM00382 91 277 3.2E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 SUPERFAMILY SSF47364 4 76 2.75E-13 T 14-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 D521_1925 464b8eaf17f8101fbd5540065a508fcf 296 Pfam PF02881 SRP54-type protein, helical bundle domain 4 68 1.4E-11 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 D521_1476 abca583aadd0346df5d3b7c2adc41c7c 114 SMART SM00411 9 99 5.7E-39 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_1476 abca583aadd0346df5d3b7c2adc41c7c 114 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 9 102 28.269 T 14-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 D521_1476 abca583aadd0346df5d3b7c2adc41c7c 114 PRINTS PR01727 Prokaryotic integration host factor signature 67 80 3.3E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_1476 abca583aadd0346df5d3b7c2adc41c7c 114 PRINTS PR01727 Prokaryotic integration host factor signature 49 64 3.3E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_1476 abca583aadd0346df5d3b7c2adc41c7c 114 PRINTS PR01727 Prokaryotic integration host factor signature 83 97 3.3E-16 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_1476 abca583aadd0346df5d3b7c2adc41c7c 114 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 9 99 3.7E-37 T 14-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 D521_1476 abca583aadd0346df5d3b7c2adc41c7c 114 Pfam PF00216 Bacterial DNA-binding protein 10 98 1.4E-28 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_1476 abca583aadd0346df5d3b7c2adc41c7c 114 SUPERFAMILY SSF47729 9 99 6.18E-29 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 D521_1476 abca583aadd0346df5d3b7c2adc41c7c 114 Gene3D G3DSA:4.10.520.10 9 101 4.1E-31 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 D521_0957 94b485e3955017bac3bd5598334ba213 364 Gene3D G3DSA:3.30.160.60 326 360 3.5E-7 T 14-10-2018 D521_0957 94b485e3955017bac3bd5598334ba213 364 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 35 353 7.9E-75 T 14-10-2018 IPR003770 Endolytic murein transglycosylase D521_0957 94b485e3955017bac3bd5598334ba213 364 Pfam PF02618 YceG-like family 65 350 4.9E-79 T 14-10-2018 IPR003770 Endolytic murein transglycosylase D521_0957 94b485e3955017bac3bd5598334ba213 364 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 34 354 31.084 T 14-10-2018 IPR003770 Endolytic murein transglycosylase D521_0957 94b485e3955017bac3bd5598334ba213 364 Gene3D G3DSA:1.10.8.1150 61 134 2.3E-5 T 14-10-2018 D521_0077 ee1c9e22dce53c54a0a3928f87d43f19 207 SMART SM00363 97 161 6.0E-15 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0077 ee1c9e22dce53c54a0a3928f87d43f19 207 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 96 2.6E-31 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 D521_0077 ee1c9e22dce53c54a0a3928f87d43f19 207 Pfam PF01479 S4 domain 98 144 1.4E-17 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0077 ee1c9e22dce53c54a0a3928f87d43f19 207 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 207 8.1E-79 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 D521_0077 ee1c9e22dce53c54a0a3928f87d43f19 207 Gene3D G3DSA:1.10.1050.10 6 207 4.9E-80 T 14-10-2018 D521_0077 ee1c9e22dce53c54a0a3928f87d43f19 207 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 207 34.87 T 14-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 D521_0077 ee1c9e22dce53c54a0a3928f87d43f19 207 ProSitePatterns PS00632 Ribosomal protein S4 signature. 95 119 - T 14-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0077 ee1c9e22dce53c54a0a3928f87d43f19 207 SMART SM01390 3 96 1.3E-45 T 14-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 D521_0077 ee1c9e22dce53c54a0a3928f87d43f19 207 SUPERFAMILY SSF55174 3 207 3.53E-65 T 14-10-2018 D521_0077 ee1c9e22dce53c54a0a3928f87d43f19 207 Gene3D G3DSA:3.10.290.10 96 192 4.9E-80 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 Gene3D G3DSA:1.20.200.10 119 448 2.0E-149 T 14-10-2018 D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 SUPERFAMILY SSF48557 12 457 1.51E-101 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 Pfam PF08328 Adenylosuccinate lyase C-terminal 333 447 5.0E-50 T 14-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 PRINTS PR00149 Fumarate lyase superfamily signature 164 182 3.4E-17 T 14-10-2018 IPR000362 Fumarate lyase family D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 PRINTS PR00149 Fumarate lyase superfamily signature 296 312 3.4E-17 T 14-10-2018 IPR000362 Fumarate lyase family D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 PRINTS PR00149 Fumarate lyase superfamily signature 118 136 3.4E-17 T 14-10-2018 IPR000362 Fumarate lyase family D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 PRINTS PR00149 Fumarate lyase superfamily signature 253 280 3.4E-17 T 14-10-2018 IPR000362 Fumarate lyase family D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 Pfam PF00206 Lyase 16 315 4.4E-57 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 Gene3D G3DSA:1.10.40.30 384 447 2.0E-149 T 14-10-2018 D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 Gene3D G3DSA:1.10.275.10 1 118 3.7E-40 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 ProSitePatterns PS00163 Fumarate lyases signature. 296 305 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 D521_1776 47056a52c5ce8e7cda8021690ff92d11 459 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 14 457 5.9E-125 T 14-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_0831 a17382907a382be5fc9ba9eb3d229ac3 232 SUPERFAMILY SSF100950 2 226 4.9E-85 T 14-10-2018 IPR037171 NagB/RpiA transferase-like D521_0831 a17382907a382be5fc9ba9eb3d229ac3 232 SMART SM00882 5 217 4.6E-88 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 D521_0831 a17382907a382be5fc9ba9eb3d229ac3 232 ProSitePatterns PS01273 Coenzyme A transferases signature 1. 18 33 - T 14-10-2018 IPR004163 Coenzyme A transferase binding site GO:0008410 Reactome: R-HSA-77108 D521_0831 a17382907a382be5fc9ba9eb3d229ac3 232 Pfam PF01144 Coenzyme A transferase 7 216 1.7E-76 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 D521_0831 a17382907a382be5fc9ba9eb3d229ac3 232 TIGRFAM TIGR02429 pcaI_scoA_fam: 3-oxoacid CoA-transferase, A subunit 1 216 4.1E-76 T 14-10-2018 IPR012792 3-oxoacid CoA-transferase, subunit A GO:0008410 Reactome: R-HSA-77108 D521_0831 a17382907a382be5fc9ba9eb3d229ac3 232 Gene3D G3DSA:3.40.1080.10 1 227 3.2E-94 T 14-10-2018 D521_0783 baf6986006a04b8c6c2ec398445bc81d 224 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 12 221 28.789 T 14-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 D521_0783 baf6986006a04b8c6c2ec398445bc81d 224 PIRSF PIRSF005461 1 224 2.7E-66 T 14-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 D521_0783 baf6986006a04b8c6c2ec398445bc81d 224 Pfam PF01728 FtsJ-like methyltransferase 28 219 3.6E-48 T 14-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 D521_0783 baf6986006a04b8c6c2ec398445bc81d 224 Gene3D G3DSA:3.40.50.150 27 224 2.7E-54 T 14-10-2018 D521_0783 baf6986006a04b8c6c2ec398445bc81d 224 SUPERFAMILY SSF53335 3 222 3.51E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0839 bf05c0e61a377319b15712b19afa1d25 348 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 87 4.8E-20 T 14-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 D521_0839 bf05c0e61a377319b15712b19afa1d25 348 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 346 46.581 T 14-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 D521_0839 bf05c0e61a377319b15712b19afa1d25 348 SUPERFAMILY SSF55681 92 347 3.08E-76 T 14-10-2018 D521_0839 bf05c0e61a377319b15712b19afa1d25 348 Pfam PF01409 tRNA synthetases class II core domain (F) 92 346 1.9E-94 T 14-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 D521_0839 bf05c0e61a377319b15712b19afa1d25 348 Gene3D G3DSA:3.30.930.10 7 347 1.9E-111 T 14-10-2018 D521_0839 bf05c0e61a377319b15712b19afa1d25 348 SUPERFAMILY SSF46589 15 99 1.62E-18 T 14-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 D521_0839 bf05c0e61a377319b15712b19afa1d25 348 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 347 2.9E-97 T 14-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 D521_1093 66b24c723879d776bb0bbeb869f7339f 560 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 5 360 5.9E-128 T 14-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 D521_1093 66b24c723879d776bb0bbeb869f7339f 560 Gene3D G3DSA:3.30.300.150 422 542 4.6E-14 T 14-10-2018 IPR038249 DNA polymerase III, tau subunit, C-terminal domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1093 66b24c723879d776bb0bbeb869f7339f 560 SUPERFAMILY SSF52540 33 230 1.36E-56 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1093 66b24c723879d776bb0bbeb869f7339f 560 SUPERFAMILY SSF48019 248 366 3.23E-24 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 D521_1093 66b24c723879d776bb0bbeb869f7339f 560 Gene3D G3DSA:3.40.50.300 13 182 5.1E-102 T 14-10-2018 D521_1093 66b24c723879d776bb0bbeb869f7339f 560 SMART SM00382 37 184 6.7E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1093 66b24c723879d776bb0bbeb869f7339f 560 Pfam PF13177 DNA polymerase III, delta subunit 20 183 5.2E-41 T 14-10-2018 D521_1093 66b24c723879d776bb0bbeb869f7339f 560 Gene3D G3DSA:1.20.272.10 247 366 1.5E-35 T 14-10-2018 D521_1093 66b24c723879d776bb0bbeb869f7339f 560 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 237 363 1.0E-21 T 14-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 D521_1093 66b24c723879d776bb0bbeb869f7339f 560 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 430 552 1.6E-15 T 14-10-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_1093 66b24c723879d776bb0bbeb869f7339f 560 Gene3D G3DSA:1.10.8.60 8 244 5.1E-102 T 14-10-2018 D521_1897 1f93239b36d417788b8d25e6ad37b310 275 Gene3D G3DSA:3.30.1130.10 12 130 7.9E-42 T 14-10-2018 D521_1897 1f93239b36d417788b8d25e6ad37b310 275 TIGRFAM TIGR03138 QueF: queuine synthase 3 275 1.9E-114 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 D521_1897 1f93239b36d417788b8d25e6ad37b310 275 Pfam PF14819 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term 12 122 2.8E-45 T 14-10-2018 IPR029139 NADPH-dependent 7-cyano-7-deazaguanine reductase, N-terminal KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 D521_1897 1f93239b36d417788b8d25e6ad37b310 275 Gene3D G3DSA:3.30.1130.10 136 275 1.4E-51 T 14-10-2018 D521_1897 1f93239b36d417788b8d25e6ad37b310 275 Hamap MF_00817 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 275 140.769 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 D521_1897 1f93239b36d417788b8d25e6ad37b310 275 Pfam PF14489 QueF-like protein 188 264 3.2E-27 T 14-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 D521_1897 1f93239b36d417788b8d25e6ad37b310 275 PIRSF PIRSF004750 1 275 6.5E-115 T 14-10-2018 IPR016428 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 2 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 D521_1897 1f93239b36d417788b8d25e6ad37b310 275 SUPERFAMILY SSF55620 178 258 1.56E-8 T 14-10-2018 D521_0101 f9f2c30519e00cf0a613e5dc992b7de0 250 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0101 f9f2c30519e00cf0a613e5dc992b7de0 250 Gene3D G3DSA:3.40.50.300 1 234 7.5E-71 T 14-10-2018 D521_0101 f9f2c30519e00cf0a613e5dc992b7de0 250 Pfam PF00005 ABC transporter 20 162 2.9E-34 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0101 f9f2c30519e00cf0a613e5dc992b7de0 250 SMART SM00382 29 209 1.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0101 f9f2c30519e00cf0a613e5dc992b7de0 250 SUPERFAMILY SSF52540 3 226 1.05E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1316 75d55e36a15960d0b2bf46cfc755d3e4 798 Pfam PF00753 Metallo-beta-lactamase superfamily 531 692 7.7E-12 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_1316 75d55e36a15960d0b2bf46cfc755d3e4 798 Pfam PF13567 Domain of unknown function (DUF4131) 4 163 1.8E-23 T 14-10-2018 IPR025405 Domain of unknown function DUF4131 D521_1316 75d55e36a15960d0b2bf46cfc755d3e4 798 SUPERFAMILY SSF56281 520 769 2.17E-38 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_1316 75d55e36a15960d0b2bf46cfc755d3e4 798 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 228 423 3.7E-27 T 14-10-2018 IPR004477 ComEC/Rec2-related protein D521_1316 75d55e36a15960d0b2bf46cfc755d3e4 798 Pfam PF03772 Competence protein 207 486 9.4E-69 T 14-10-2018 IPR004477 ComEC/Rec2-related protein D521_1316 75d55e36a15960d0b2bf46cfc755d3e4 798 Gene3D G3DSA:3.60.15.10 522 776 3.8E-53 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_1316 75d55e36a15960d0b2bf46cfc755d3e4 798 SMART SM00849 532 738 0.0012 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_1316 75d55e36a15960d0b2bf46cfc755d3e4 798 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 120 767 5.6E-105 T 14-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 Gene3D G3DSA:2.40.50.100 3 81 5.4E-21 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 156 166 - T 14-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 SUPERFAMILY SSF51230 4 95 8.11E-22 T 14-10-2018 IPR011053 Single hybrid motif D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 Gene3D G3DSA:3.50.50.60 122 455 2.9E-116 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 SUPERFAMILY SSF51905 118 460 4.65E-51 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 121 584 3.4E-141 T 14-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 Gene3D G3DSA:3.30.390.30 469 589 1.6E-44 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 298 316 4.1E-39 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 415 437 4.1E-39 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 123 142 4.1E-39 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 386 402 4.1E-39 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 278 4.1E-39 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 SUPERFAMILY SSF55424 465 589 1.39E-38 T 14-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 122 144 1.1E-69 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 298 323 1.1E-69 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 552 572 1.1E-69 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 263 272 1.1E-69 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 170 1.1E-69 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 387 401 1.1E-69 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 437 1.1E-69 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 465 486 1.1E-69 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 530 545 1.1E-69 T 14-10-2018 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 PIRSF PIRSF000350 50 589 1.6E-80 T 14-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 Gene3D G3DSA:3.50.50.60 275 396 2.9E-116 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 469 577 1.8E-32 T 14-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 122 450 3.1E-55 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 D521_1034 8fd5fbde2a0169fd7f81e1dbcfb141e0 596 Pfam PF00364 Biotin-requiring enzyme 6 76 1.6E-19 T 14-10-2018 IPR000089 Biotin/lipoyl attachment D521_2063 f43d0325277ff08e15d0828533209e7a 248 Gene3D G3DSA:1.10.150.130 101 215 6.8E-6 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal D521_2063 f43d0325277ff08e15d0828533209e7a 248 SUPERFAMILY SSF56349 105 234 1.08E-8 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_1600 f43d0325277ff08e15d0828533209e7a 248 Gene3D G3DSA:1.10.150.130 101 215 6.8E-6 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal D521_1600 f43d0325277ff08e15d0828533209e7a 248 SUPERFAMILY SSF56349 105 234 1.08E-8 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_0592 3a0d95c0521053aa4b25883f39b800ff 415 Pfam PF13088 BNR repeat-like domain 96 382 4.8E-73 T 14-10-2018 IPR011040 Sialidase KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 D521_0592 3a0d95c0521053aa4b25883f39b800ff 415 SUPERFAMILY SSF50939 77 403 1.15E-37 T 14-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 D521_0592 3a0d95c0521053aa4b25883f39b800ff 415 Gene3D G3DSA:2.120.10.10 81 369 3.4E-8 T 14-10-2018 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 Gene3D G3DSA:3.40.50.620 129 452 8.4E-152 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 Gene3D G3DSA:1.10.730.10 453 575 8.4E-152 T 14-10-2018 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 Pfam PF05746 DALR anticodon binding domain 458 575 9.0E-37 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 SUPERFAMILY SSF52374 129 468 1.26E-78 T 14-10-2018 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 138 147 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 SMART SM01016 7 97 6.4E-33 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 Hamap MF_00123 Arginine--tRNA ligase [argS]. 7 575 25.188 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 Pfam PF00750 tRNA synthetases class I (R) 123 401 4.9E-16 T 14-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 97 1.5E-23 T 14-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 Gene3D G3DSA:3.30.1360.70 4 117 3.3E-23 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 PRINTS PR01038 Arginyl-tRNA synthetase signature 143 159 2.4E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 PRINTS PR01038 Arginyl-tRNA synthetase signature 303 324 2.4E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 PRINTS PR01038 Arginyl-tRNA synthetase signature 167 180 2.4E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 PRINTS PR01038 Arginyl-tRNA synthetase signature 128 143 2.4E-21 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 SMART SM00836 458 575 4.6E-53 T 14-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 10 575 1.2E-120 T 14-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 SUPERFAMILY SSF55190 6 117 1.96E-21 T 14-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 D521_1975 4de11f4d405fdd8638eb210e8ec8f9ef 575 SUPERFAMILY SSF47323 453 575 2.81E-37 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1959 b577549842f2bb281c32aa98876879c5 338 SUPERFAMILY SSF102114 64 333 6.02E-63 T 14-10-2018 D521_1959 b577549842f2bb281c32aa98876879c5 338 Hamap MF_00206 Lipoyl synthase [lipA]. 49 338 147.947 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 D521_1959 b577549842f2bb281c32aa98876879c5 338 SMART SM00729 97 309 4.4E-16 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 D521_1959 b577549842f2bb281c32aa98876879c5 338 TIGRFAM TIGR00510 lipA: lipoyl synthase 45 332 8.5E-124 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 D521_1959 b577549842f2bb281c32aa98876879c5 338 Gene3D G3DSA:3.20.20.70 94 306 6.6E-18 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1959 b577549842f2bb281c32aa98876879c5 338 PIRSF PIRSF005963 3 337 7.5E-123 T 14-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 D521_1959 b577549842f2bb281c32aa98876879c5 338 Pfam PF04055 Radical SAM superfamily 104 268 2.6E-13 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 D521_1129 00aab6fafe6b88e9b02bc20a668fb4bc 291 Pfam PF12849 PBP superfamily domain 45 262 3.0E-17 T 14-10-2018 IPR024370 PBP domain D521_1129 00aab6fafe6b88e9b02bc20a668fb4bc 291 Gene3D G3DSA:3.40.190.10 48 268 3.6E-65 T 14-10-2018 D521_1129 00aab6fafe6b88e9b02bc20a668fb4bc 291 Gene3D G3DSA:3.40.190.10 120 233 3.6E-65 T 14-10-2018 D521_1129 00aab6fafe6b88e9b02bc20a668fb4bc 291 SUPERFAMILY SSF53850 54 271 1.36E-23 T 14-10-2018 D521_1788 5c24b18e594023cc8bcc815eb3c466a2 369 TIGRFAM TIGR02818 adh_III_F_hyde: S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 2 369 8.1E-222 T 14-10-2018 IPR014183 Alcohol dehydrogenase class III GO:0006069|GO:0008270|GO:0051903|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00680+1.1.1.284|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-1801|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396|MetaCyc: PWY-7798|Reactome: R-HSA-71384 D521_1788 5c24b18e594023cc8bcc815eb3c466a2 369 Gene3D G3DSA:3.90.180.10 6 364 2.4E-148 T 14-10-2018 D521_1788 5c24b18e594023cc8bcc815eb3c466a2 369 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 D521_1788 5c24b18e594023cc8bcc815eb3c466a2 369 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 154 1.4E-26 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 D521_1788 5c24b18e594023cc8bcc815eb3c466a2 369 SUPERFAMILY SSF50129 318 369 1.2E-11 T 14-10-2018 IPR011032 GroES-like superfamily D521_1788 5c24b18e594023cc8bcc815eb3c466a2 369 SUPERFAMILY SSF50129 1 185 2.65E-70 T 14-10-2018 IPR011032 GroES-like superfamily D521_1788 5c24b18e594023cc8bcc815eb3c466a2 369 Pfam PF00107 Zinc-binding dehydrogenase 197 330 4.0E-24 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 D521_1788 5c24b18e594023cc8bcc815eb3c466a2 369 SMART SM00829 10 367 9.9E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 D521_1788 5c24b18e594023cc8bcc815eb3c466a2 369 Gene3D G3DSA:3.40.50.720 174 312 2.4E-148 T 14-10-2018 D521_1788 5c24b18e594023cc8bcc815eb3c466a2 369 SUPERFAMILY SSF51735 160 333 1.17E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1854 93f6cee73b320f5abe9a40166f8ce9ec 157 Pfam PF02130 Uncharacterized protein family UPF0054 32 147 4.0E-28 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 D521_1854 93f6cee73b320f5abe9a40166f8ce9ec 157 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 11 152 19.221 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 D521_1854 93f6cee73b320f5abe9a40166f8ce9ec 157 SUPERFAMILY SSF55486 24 154 6.78E-36 T 14-10-2018 D521_1854 93f6cee73b320f5abe9a40166f8ce9ec 157 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 48 149 5.0E-30 T 14-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 D521_1854 93f6cee73b320f5abe9a40166f8ce9ec 157 Gene3D G3DSA:3.40.390.30 8 156 2.8E-39 T 14-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 D521_1075 fdc55242b753e0619b9b5b0d569b96f2 439 SUPERFAMILY SSF55681 13 324 1.51E-97 T 14-10-2018 D521_1075 fdc55242b753e0619b9b5b0d569b96f2 439 PIRSF PIRSF001549 9 434 2.4E-116 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 D521_1075 fdc55242b753e0619b9b5b0d569b96f2 439 Gene3D G3DSA:3.30.930.10 10 332 7.4E-122 T 14-10-2018 D521_1075 fdc55242b753e0619b9b5b0d569b96f2 439 Pfam PF03129 Anticodon binding domain 339 431 5.3E-10 T 14-10-2018 IPR004154 Anticodon-binding D521_1075 fdc55242b753e0619b9b5b0d569b96f2 439 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 11 432 32.373 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 D521_1075 fdc55242b753e0619b9b5b0d569b96f2 439 Pfam PF13393 Histidyl-tRNA synthetase 18 320 4.6E-51 T 14-10-2018 D521_1075 fdc55242b753e0619b9b5b0d569b96f2 439 Gene3D G3DSA:3.40.50.800 335 430 1.1E-24 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily D521_1075 fdc55242b753e0619b9b5b0d569b96f2 439 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 16 422 5.9E-153 T 14-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 D521_1075 fdc55242b753e0619b9b5b0d569b96f2 439 SUPERFAMILY SSF52954 335 432 1.8E-19 T 14-10-2018 D521_1374 c108af1209cbb891f8edffc554ae6bdc 241 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 1 221 1.2E-36 T 14-10-2018 IPR018713 Domain of unknown function DUF2236 D521_0732 9051f404aafce3110ddffaedad2c8799 189 Gene3D G3DSA:1.10.10.10 103 184 1.0E-17 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0732 9051f404aafce3110ddffaedad2c8799 189 Pfam PF08281 Sigma-70, region 4 126 177 7.1E-15 T 14-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 D521_0732 9051f404aafce3110ddffaedad2c8799 189 SUPERFAMILY SSF88946 11 82 2.79E-8 T 14-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 D521_0732 9051f404aafce3110ddffaedad2c8799 189 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 7 182 1.3E-19 T 14-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 D521_0732 9051f404aafce3110ddffaedad2c8799 189 SUPERFAMILY SSF88659 120 182 1.74E-14 T 14-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 TIGRFAM TIGR01083 nth: endonuclease III 6 195 5.6E-86 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 Pfam PF00633 Helix-hairpin-helix motif 101 128 2.8E-10 T 14-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 PIRSF PIRSF001435 1 212 4.7E-53 T 14-10-2018 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 SMART SM00278 110 129 0.005 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 Gene3D G3DSA:1.10.340.30 22 133 8.4E-77 T 14-10-2018 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 14-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 SUPERFAMILY SSF48150 2 209 1.54E-71 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 SMART SM00478 39 186 3.9E-58 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 SMART SM00525 187 207 0.0025 T 14-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 169 8.7E-18 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 Hamap MF_00942 Endonuclease III [nth]. 4 210 37.298 T 14-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 D521_1357 52a3d8980fd9425970a3eb8fbbbd3b97 219 Gene3D G3DSA:1.10.1670.10 13 204 8.4E-77 T 14-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 D521_1057 bb0210b38b43d4b5c3b1c6399d24596a 251 Pfam PF00588 SpoU rRNA Methylase family 100 239 2.0E-39 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 D521_1057 bb0210b38b43d4b5c3b1c6399d24596a 251 SUPERFAMILY SSF75217 95 247 1.7E-47 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases D521_1057 bb0210b38b43d4b5c3b1c6399d24596a 251 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 4 77 2.5E-13 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 D521_1057 bb0210b38b43d4b5c3b1c6399d24596a 251 SMART SM00967 4 81 3.5E-14 T 14-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 D521_1057 bb0210b38b43d4b5c3b1c6399d24596a 251 SUPERFAMILY SSF55315 3 76 3.65E-12 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like D521_1057 bb0210b38b43d4b5c3b1c6399d24596a 251 Gene3D G3DSA:3.40.1280.10 81 246 7.1E-60 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal D521_1057 bb0210b38b43d4b5c3b1c6399d24596a 251 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 2 246 42.092 T 14-10-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB D521_1057 bb0210b38b43d4b5c3b1c6399d24596a 251 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 2 245 1.8E-69 T 14-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 D521_1057 bb0210b38b43d4b5c3b1c6399d24596a 251 Gene3D G3DSA:3.30.1330.30 1 76 3.4E-13 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like D521_1151 b00a7b563bed19cec8756696e058700c 216 PIRSF PIRSF036226 1 202 4.5E-63 T 14-10-2018 IPR014602 Uncharacterised conserved protein UCP036226 D521_1151 b00a7b563bed19cec8756696e058700c 216 Gene3D G3DSA:2.40.128.20 18 195 7.8E-9 T 14-10-2018 IPR012674 Calycin D521_1151 b00a7b563bed19cec8756696e058700c 216 Pfam PF08768 Domain of unknown function (DUF1794) 22 198 4.2E-20 T 14-10-2018 IPR014878 Domain of unknown function DUF1794 D521_1151 b00a7b563bed19cec8756696e058700c 216 SUPERFAMILY SSF50814 22 199 2.08E-25 T 14-10-2018 IPR012674 Calycin D521_0474 cc5341258f5b580ff565da8ca068c80c 472 Gene3D G3DSA:3.40.50.300 7 233 1.6E-83 T 14-10-2018 D521_0474 cc5341258f5b580ff565da8ca068c80c 472 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 179 187 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site D521_0474 cc5341258f5b580ff565da8ca068c80c 472 Pfam PF00270 DEAD/DEAH box helicase 48 222 2.9E-52 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 D521_0474 cc5341258f5b580ff565da8ca068c80c 472 SMART SM00490 288 369 1.1E-29 T 14-10-2018 IPR001650 Helicase, C-terminal D521_0474 cc5341258f5b580ff565da8ca068c80c 472 Gene3D G3DSA:3.40.50.300 234 403 1.1E-48 T 14-10-2018 D521_0474 cc5341258f5b580ff565da8ca068c80c 472 SUPERFAMILY SSF52540 101 387 4.06E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0474 cc5341258f5b580ff565da8ca068c80c 472 SMART SM00487 43 248 8.6E-62 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_0474 cc5341258f5b580ff565da8ca068c80c 472 Pfam PF00271 Helicase conserved C-terminal domain 259 369 1.7E-25 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1779 b06e3d10eca5f680fda1c6d4e59815dc 376 SUPERFAMILY SSF51735 155 339 4.98E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1779 b06e3d10eca5f680fda1c6d4e59815dc 376 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 14-10-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 D521_1779 b06e3d10eca5f680fda1c6d4e59815dc 376 Gene3D G3DSA:3.40.50.720 136 325 1.1E-136 T 14-10-2018 D521_1779 b06e3d10eca5f680fda1c6d4e59815dc 376 SUPERFAMILY SSF52283 1 167 1.19E-50 T 14-10-2018 D521_1779 b06e3d10eca5f680fda1c6d4e59815dc 376 SMART SM01003 4 136 1.7E-64 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal D521_1779 b06e3d10eca5f680fda1c6d4e59815dc 376 Gene3D G3DSA:3.40.50.720 3 371 1.1E-136 T 14-10-2018 D521_1779 b06e3d10eca5f680fda1c6d4e59815dc 376 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 1.2E-40 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal D521_1779 b06e3d10eca5f680fda1c6d4e59815dc 376 SMART SM01002 145 318 8.7E-81 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain D521_1779 b06e3d10eca5f680fda1c6d4e59815dc 376 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 373 1.5E-68 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain D521_1067 69504931830b5760a6ed840594dc4086 387 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 12 321 2.0E-87 T 14-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 D521_1067 69504931830b5760a6ed840594dc4086 387 PIRSF PIRSF001549 5 385 4.1E-49 T 14-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 D521_1067 69504931830b5760a6ed840594dc4086 387 Pfam PF13393 Histidyl-tRNA synthetase 10 316 2.9E-111 T 14-10-2018 D521_1067 69504931830b5760a6ed840594dc4086 387 Gene3D G3DSA:3.30.930.10 3 326 5.1E-70 T 14-10-2018 D521_1067 69504931830b5760a6ed840594dc4086 387 SUPERFAMILY SSF55681 5 315 8.87E-60 T 14-10-2018 D521_1067 69504931830b5760a6ed840594dc4086 387 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 16 369 31.386 T 14-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 D521_2092 ebdbfa43255ae7ece00968e4b9ba3af8 229 Pfam PF13505 Outer membrane protein beta-barrel domain 15 229 1.4E-9 T 14-10-2018 IPR027385 Outer membrane protein beta-barrel D521_2092 ebdbfa43255ae7ece00968e4b9ba3af8 229 SUPERFAMILY SSF56925 27 229 5.49E-9 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 3 205 5.4E-59 T 14-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 161 181 4.8E-24 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 188 201 4.8E-24 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 4.8E-24 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 143 159 4.8E-24 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 112 125 4.8E-24 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 Gene3D G3DSA:1.10.150.240 16 97 1.7E-65 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 5 190 6.4E-23 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 Gene3D G3DSA:3.40.50.1000 5 213 1.7E-65 T 14-10-2018 IPR023214 HAD superfamily D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 85 199 2.3E-16 T 14-10-2018 D521_2054 5cb936cb20551e6a941fc5dd4d4ee129 227 SUPERFAMILY SSF56784 1 227 2.48E-46 T 14-10-2018 IPR036412 HAD-like superfamily D521_0258 3b570b212762390b59b74ee1b8c184de 283 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 274 17.481 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 D521_0258 3b570b212762390b59b74ee1b8c184de 283 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 267 3.6E-67 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 D521_0258 3b570b212762390b59b74ee1b8c184de 283 Pfam PF02673 Bacitracin resistance protein BacA 9 269 8.2E-80 T 14-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 D521_0069 5067ed5c2268b20bc459b418db5ba134 172 Pfam PF03719 Ribosomal protein S5, C-terminal domain 93 163 1.0E-29 T 14-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 D521_0069 5067ed5c2268b20bc459b418db5ba134 172 Pfam PF00333 Ribosomal protein S5, N-terminal domain 17 80 1.4E-24 T 14-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 D521_0069 5067ed5c2268b20bc459b418db5ba134 172 Gene3D G3DSA:3.30.160.20 7 79 5.7E-26 T 14-10-2018 D521_0069 5067ed5c2268b20bc459b418db5ba134 172 SUPERFAMILY SSF54768 14 82 3.87E-21 T 14-10-2018 D521_0069 5067ed5c2268b20bc459b418db5ba134 172 ProSitePatterns PS00585 Ribosomal protein S5 signature. 34 66 - T 14-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site D521_0069 5067ed5c2268b20bc459b418db5ba134 172 SUPERFAMILY SSF54211 85 165 1.24E-25 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0069 5067ed5c2268b20bc459b418db5ba134 172 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 169 33.962 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 D521_0069 5067ed5c2268b20bc459b418db5ba134 172 Gene3D G3DSA:3.30.230.10 80 172 3.5E-37 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup D521_0069 5067ed5c2268b20bc459b418db5ba134 172 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 16 169 2.6E-64 T 14-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 D521_0421 b6e97228a16d3c1cb437156466425eda 593 SUPERFAMILY SSF55874 470 592 2.75E-18 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0421 b6e97228a16d3c1cb437156466425eda 593 SUPERFAMILY SSF55781 223 383 8.07E-16 T 14-10-2018 D521_0421 b6e97228a16d3c1cb437156466425eda 593 Gene3D G3DSA:1.20.120.960 16 128 5.8E-10 T 14-10-2018 D521_0421 b6e97228a16d3c1cb437156466425eda 593 SMART SM00387 501 593 3.4E-11 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_0421 b6e97228a16d3c1cb437156466425eda 593 Pfam PF07730 Histidine kinase 396 462 6.3E-17 T 14-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 D521_0421 b6e97228a16d3c1cb437156466425eda 593 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 503 592 5.4E-8 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_0421 b6e97228a16d3c1cb437156466425eda 593 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 9 98 7.6E-18 T 14-10-2018 IPR029095 NarX-like, N-terminal D521_0421 b6e97228a16d3c1cb437156466425eda 593 SUPERFAMILY SSF158472 159 207 2.75E-6 T 14-10-2018 D521_0421 b6e97228a16d3c1cb437156466425eda 593 SMART SM00304 157 209 5.8E-7 T 14-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 D521_0421 b6e97228a16d3c1cb437156466425eda 593 Gene3D G3DSA:3.30.565.10 463 593 1.3E-25 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0421 b6e97228a16d3c1cb437156466425eda 593 Gene3D G3DSA:3.30.450.40 219 392 4.2E-16 T 14-10-2018 IPR029016 GAF-like domain superfamily D521_0421 b6e97228a16d3c1cb437156466425eda 593 PIRSF PIRSF003167 1 593 2.4E-157 T 14-10-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 D521_0087 965b9fac3273c1c58f7b013e7069679a 360 SUPERFAMILY SSF56796 4 353 2.22E-116 T 14-10-2018 D521_0087 965b9fac3273c1c58f7b013e7069679a 360 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 355 70.64 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 D521_0087 965b9fac3273c1c58f7b013e7069679a 360 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 353 2.5E-123 T 14-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 D521_0087 965b9fac3273c1c58f7b013e7069679a 360 Gene3D G3DSA:1.20.1090.10 173 358 8.1E-66 T 14-10-2018 D521_0087 965b9fac3273c1c58f7b013e7069679a 360 Pfam PF01761 3-dehydroquinate synthase 67 324 6.7E-109 T 14-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 D521_0087 965b9fac3273c1c58f7b013e7069679a 360 Gene3D G3DSA:3.40.50.1970 1 172 1.5E-68 T 14-10-2018 D521_0087 965b9fac3273c1c58f7b013e7069679a 360 PIRSF PIRSF001455 3 359 6.5E-112 T 14-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 D521_0963 e43eb3baede8f4d6d23555cf7a7bd6b0 94 SUPERFAMILY SSF82657 9 91 3.01E-23 T 14-10-2018 IPR036065 BolA-like superfamily D521_0963 e43eb3baede8f4d6d23555cf7a7bd6b0 94 Gene3D G3DSA:3.30.300.90 5 94 5.4E-27 T 14-10-2018 D521_0963 e43eb3baede8f4d6d23555cf7a7bd6b0 94 Pfam PF01722 BolA-like protein 15 91 1.6E-27 T 14-10-2018 IPR002634 BolA protein D521_0963 e43eb3baede8f4d6d23555cf7a7bd6b0 94 PIRSF PIRSF003113 1 94 6.1E-25 T 14-10-2018 IPR002634 BolA protein D521_0867 f836d468259c756f4216cbb78a6fa029 441 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 212 1.2E-54 T 14-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 D521_0867 f836d468259c756f4216cbb78a6fa029 441 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 366 407 2.6E-8 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 D521_0867 f836d468259c756f4216cbb78a6fa029 441 Pfam PF09179 TilS substrate binding domain 263 324 7.2E-12 T 14-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 D521_0867 f836d468259c756f4216cbb78a6fa029 441 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 11 318 23.231 T 14-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 D521_0867 f836d468259c756f4216cbb78a6fa029 441 SMART SM00977 363 434 2.3E-14 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 D521_0867 f836d468259c756f4216cbb78a6fa029 441 Pfam PF11734 TilS substrate C-terminal domain 366 425 1.5E-17 T 14-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 D521_0867 f836d468259c756f4216cbb78a6fa029 441 SUPERFAMILY SSF52402 17 241 5.07E-56 T 14-10-2018 D521_0867 f836d468259c756f4216cbb78a6fa029 441 SUPERFAMILY SSF82829 243 327 1.44E-15 T 14-10-2018 D521_0867 f836d468259c756f4216cbb78a6fa029 441 SUPERFAMILY SSF56037 351 434 1.46E-16 T 14-10-2018 D521_0867 f836d468259c756f4216cbb78a6fa029 441 Gene3D G3DSA:3.40.50.620 11 240 3.6E-65 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0867 f836d468259c756f4216cbb78a6fa029 441 Gene3D G3DSA:1.20.59.20 241 327 2.2E-8 T 14-10-2018 D521_0867 f836d468259c756f4216cbb78a6fa029 441 Pfam PF01171 PP-loop family 21 209 1.8E-54 T 14-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 D521_0157 8d6d632a9bc4c93c39a616dea8552d82 409 Gene3D G3DSA:3.90.1150.10 47 395 2.9E-116 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_0157 8d6d632a9bc4c93c39a616dea8552d82 409 Pfam PF00155 Aminotransferase class I and II 48 397 1.2E-47 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 D521_0157 8d6d632a9bc4c93c39a616dea8552d82 409 Gene3D G3DSA:3.40.640.10 61 302 2.9E-116 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0157 8d6d632a9bc4c93c39a616dea8552d82 409 SUPERFAMILY SSF53383 12 401 6.45E-90 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_2044 f21c33cbf8de2eacf78f26faa4bddd31 250 SUPERFAMILY SSF53850 5 248 4.08E-50 T 14-10-2018 D521_2044 f21c33cbf8de2eacf78f26faa4bddd31 250 Gene3D G3DSA:3.40.190.10 114 212 7.5E-57 T 14-10-2018 D521_2044 f21c33cbf8de2eacf78f26faa4bddd31 250 SMART SM00079 28 250 0.002 T 14-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 D521_2044 f21c33cbf8de2eacf78f26faa4bddd31 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 249 1.2E-42 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF D521_2044 f21c33cbf8de2eacf78f26faa4bddd31 250 Gene3D G3DSA:3.40.190.10 29 233 7.5E-57 T 14-10-2018 D521_2044 f21c33cbf8de2eacf78f26faa4bddd31 250 SMART SM00062 28 249 3.0E-32 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF D521_0016 1975986e3ed8174b45084a69cf5811db 291 ProSitePatterns PS00449 ATP synthase a subunit signature. 214 223 - T 14-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0016 1975986e3ed8174b45084a69cf5811db 291 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 41 286 1.6E-42 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0016 1975986e3ed8174b45084a69cf5811db 291 Gene3D G3DSA:1.20.120.220 98 291 3.0E-50 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0016 1975986e3ed8174b45084a69cf5811db 291 SUPERFAMILY SSF81336 99 285 1.7E-39 T 14-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0016 1975986e3ed8174b45084a69cf5811db 291 Hamap MF_01393 ATP synthase subunit a [atpB]. 39 291 14.262 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0016 1975986e3ed8174b45084a69cf5811db 291 Pfam PF00119 ATP synthase A chain 50 284 3.3E-52 T 14-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0339 ffe9349a51a03451236d09402bdb1d4b 121 PIRSF PIRSF018297 1 121 1.2E-30 T 14-10-2018 IPR006440 Death on curing protein GO:0016301 D521_0339 ffe9349a51a03451236d09402bdb1d4b 121 Pfam PF02661 Fic/DOC family 4 80 1.6E-11 T 14-10-2018 IPR003812 Fido domain D521_0339 ffe9349a51a03451236d09402bdb1d4b 121 Gene3D G3DSA:1.20.120.1870 1 121 9.0E-32 T 14-10-2018 D521_0339 ffe9349a51a03451236d09402bdb1d4b 121 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 4 117 7.7E-15 T 14-10-2018 IPR006440 Death on curing protein GO:0016301 D521_0339 ffe9349a51a03451236d09402bdb1d4b 121 SUPERFAMILY SSF140931 4 107 4.05E-10 T 14-10-2018 IPR036597 Fido-like domain superfamily D521_1101 0a342ab11172c2eca88dabd6705f0801 180 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 180 88.202 T 14-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria D521_1101 0a342ab11172c2eca88dabd6705f0801 180 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 17 180 2.4E-59 T 14-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria D521_1101 0a342ab11172c2eca88dabd6705f0801 180 Pfam PF03350 Uncharacterized protein family, UPF0114 20 138 9.1E-40 T 14-10-2018 IPR005134 Uncharacterised protein family UPF0114 D521_0586 ee01acd2015faa58d3bf71bf9605236f 245 SUPERFAMILY SSF51182 12 242 1.28E-74 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily D521_0586 ee01acd2015faa58d3bf71bf9605236f 245 Gene3D G3DSA:2.60.120.10 23 143 3.3E-57 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_0586 ee01acd2015faa58d3bf71bf9605236f 245 PIRSF PIRSF006232 9 241 3.0E-52 T 14-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 D521_0586 ee01acd2015faa58d3bf71bf9605236f 245 Gene3D G3DSA:2.60.120.10 144 245 5.7E-30 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_0586 ee01acd2015faa58d3bf71bf9605236f 245 Pfam PF02678 Pirin 18 130 1.1E-34 T 14-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 D521_0591 28a945084ad1cef6007d1c9557c96765 552 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 18 218 3.6E-8 T 14-10-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 PIRSF PIRSF000183 1 371 4.8E-152 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 ProSitePatterns PS00836 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 1. 4 30 - T 14-10-2018 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 GO:0016491|GO:0055114 Reactome: R-HSA-71403 D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 Gene3D G3DSA:3.40.50.720 130 305 1.5E-136 T 14-10-2018 D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 SUPERFAMILY SSF51735 137 303 9.3E-49 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 SMART SM01003 4 137 2.2E-73 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 1.5E-81 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 5.1E-45 T 14-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 SUPERFAMILY SSF52283 1 358 4.59E-61 T 14-10-2018 D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 14-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 2.5E-152 T 14-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 Gene3D G3DSA:3.40.50.720 3 353 1.5E-136 T 14-10-2018 D521_0530 d3e8fd58b2b69ecad5371a076032e578 372 SMART SM01002 149 297 8.3E-87 T 14-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain D521_1601 a4a45e4c34abfb4eb67670680073228a 478 Gene3D G3DSA:3.40.50.10540 308 424 3.8E-49 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_1601 a4a45e4c34abfb4eb67670680073228a 478 Gene3D G3DSA:3.40.50.620 3 183 1.8E-53 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1601 a4a45e4c34abfb4eb67670680073228a 478 SUPERFAMILY SSF52402 3 186 3.01E-54 T 14-10-2018 D521_1601 a4a45e4c34abfb4eb67670680073228a 478 Gene3D G3DSA:3.40.50.1220 184 304 4.8E-55 T 14-10-2018 D521_1601 a4a45e4c34abfb4eb67670680073228a 478 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 254 280 - T 14-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 D521_1601 a4a45e4c34abfb4eb67670680073228a 478 Pfam PF02515 CoA-transferase family III 308 472 9.9E-55 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 D521_1601 a4a45e4c34abfb4eb67670680073228a 478 SUPERFAMILY SSF52467 187 308 7.09E-45 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily D521_1601 a4a45e4c34abfb4eb67670680073228a 478 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 190 273 4.1E-34 T 14-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 D521_1601 a4a45e4c34abfb4eb67670680073228a 478 Gene3D G3DSA:3.30.1540.10 425 472 3.8E-49 T 14-10-2018 D521_1601 a4a45e4c34abfb4eb67670680073228a 478 Pfam PF01012 Electron transfer flavoprotein domain 4 170 5.9E-37 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 D521_1601 a4a45e4c34abfb4eb67670680073228a 478 SMART SM00893 3 182 4.1E-55 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 D521_1601 a4a45e4c34abfb4eb67670680073228a 478 SUPERFAMILY SSF89796 307 473 5.1E-55 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_0927 43aa9cb7ceb3240ac772870acdc4677c 167 Pfam PF02542 YgbB family 11 164 3.1E-62 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 D521_0927 43aa9cb7ceb3240ac772870acdc4677c 167 SUPERFAMILY SSF69765 10 166 4.84E-63 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 D521_0927 43aa9cb7ceb3240ac772870acdc4677c 167 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 12 166 1.3E-62 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 D521_0927 43aa9cb7ceb3240ac772870acdc4677c 167 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 11 166 34.599 T 14-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 D521_0927 43aa9cb7ceb3240ac772870acdc4677c 167 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 45 60 - T 14-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 D521_0927 43aa9cb7ceb3240ac772870acdc4677c 167 Gene3D G3DSA:3.30.1330.50 9 167 5.8E-67 T 14-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 D521_0635 097533213427c82b161b294174003a7e 412 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 11 54 1.7E-11 T 14-10-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal D521_1041 b302a495a4a4eea801d5e26a771ae2a2 281 Gene3D G3DSA:3.60.10.10 5 280 2.5E-67 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily D521_1041 b302a495a4a4eea801d5e26a771ae2a2 281 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 6 280 9.8E-68 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 D521_1041 b302a495a4a4eea801d5e26a771ae2a2 281 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 236 247 - T 14-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 D521_1041 b302a495a4a4eea801d5e26a771ae2a2 281 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 9 272 4.0E-15 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase D521_1041 b302a495a4a4eea801d5e26a771ae2a2 281 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 6 279 2.5E-72 T 14-10-2018 D521_1041 b302a495a4a4eea801d5e26a771ae2a2 281 SUPERFAMILY SSF56219 6 280 3.4E-72 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily D521_1985 8dbf62551f2dc6849f20e0b46923255b 220 SUPERFAMILY SSF52833 1 88 7.63E-24 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1985 8dbf62551f2dc6849f20e0b46923255b 220 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 84 8.2E-15 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 D521_1985 8dbf62551f2dc6849f20e0b46923255b 220 Gene3D G3DSA:1.20.1050.10 88 211 4.1E-35 T 14-10-2018 D521_1985 8dbf62551f2dc6849f20e0b46923255b 220 SUPERFAMILY SSF47616 76 209 9.47E-17 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily D521_1985 8dbf62551f2dc6849f20e0b46923255b 220 Gene3D G3DSA:3.40.30.10 1 86 2.1E-34 T 14-10-2018 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 140 160 - T 14-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 Gene3D G3DSA:3.50.50.60 14 315 9.2E-120 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 12 316 1.3E-113 T 14-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 Gene3D G3DSA:3.50.50.60 122 247 9.2E-120 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 7.3E-39 T 14-10-2018 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 7.3E-39 T 14-10-2018 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 7.3E-39 T 14-10-2018 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 13 32 7.3E-39 T 14-10-2018 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 110 128 7.3E-39 T 14-10-2018 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 111 119 1.6E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 133 145 1.6E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 279 297 1.6E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 12 34 1.6E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 1.6E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 148 172 1.6E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 1.6E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 241 262 1.6E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 45 60 1.6E-75 T 14-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 SUPERFAMILY SSF51905 4 316 8.38E-54 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0552 680e862d6162fcd047cdb6e3fb8c7b76 320 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 304 2.5E-47 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 D521_0147 d0e2952c697bd7e9b12696504c0d3f0b 340 Pfam PF00591 Glycosyl transferase family, a/b domain 77 328 6.9E-96 T 14-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 D521_0147 d0e2952c697bd7e9b12696504c0d3f0b 340 Gene3D G3DSA:3.40.1030.10 73 340 4.8E-112 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 D521_0147 d0e2952c697bd7e9b12696504c0d3f0b 340 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 7 337 37.977 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 D521_0147 d0e2952c697bd7e9b12696504c0d3f0b 340 SUPERFAMILY SSF47648 4 71 1.1E-17 T 14-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 D521_0147 d0e2952c697bd7e9b12696504c0d3f0b 340 SUPERFAMILY SSF52418 77 339 5.89E-100 T 14-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 D521_0147 d0e2952c697bd7e9b12696504c0d3f0b 340 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 9 336 1.4E-129 T 14-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 D521_0147 d0e2952c697bd7e9b12696504c0d3f0b 340 Gene3D G3DSA:1.20.970.10 1 72 4.5E-31 T 14-10-2018 D521_0147 d0e2952c697bd7e9b12696504c0d3f0b 340 Pfam PF02885 Glycosyl transferase family, helical bundle domain 7 68 5.5E-14 T 14-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 D521_0159 b52f97e2bceff54fc0886250771d930f 345 TIGRFAM TIGR00433 bioB: biotin synthase 38 334 1.5E-121 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 D521_0159 b52f97e2bceff54fc0886250771d930f 345 SMART SM00876 243 335 6.8E-46 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 D521_0159 b52f97e2bceff54fc0886250771d930f 345 SUPERFAMILY SSF102114 29 334 9.55E-85 T 14-10-2018 D521_0159 b52f97e2bceff54fc0886250771d930f 345 PIRSF PIRSF001619 11 342 6.0E-129 T 14-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 D521_0159 b52f97e2bceff54fc0886250771d930f 345 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 243 334 7.9E-18 T 14-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 D521_0159 b52f97e2bceff54fc0886250771d930f 345 SMART SM00729 66 278 2.9E-37 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 D521_0159 b52f97e2bceff54fc0886250771d930f 345 Pfam PF04055 Radical SAM superfamily 73 229 2.0E-13 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 D521_0159 b52f97e2bceff54fc0886250771d930f 345 Hamap MF_01694 Biotin synthase [bioB]. 28 336 41.68 T 14-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 D521_0159 b52f97e2bceff54fc0886250771d930f 345 Gene3D G3DSA:3.20.20.70 28 338 2.7E-123 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0481 92b6e8ec71a36226328fa32eaee180ba 487 SUPERFAMILY SSF50249 39 117 5.29E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_0481 92b6e8ec71a36226328fa32eaee180ba 487 Gene3D G3DSA:2.40.50.140 31 117 1.1E-27 T 14-10-2018 D521_0481 92b6e8ec71a36226328fa32eaee180ba 487 SMART SM00316 37 111 6.0E-8 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_0481 92b6e8ec71a36226328fa32eaee180ba 487 Pfam PF10150 Ribonuclease E/G family 113 391 6.9E-99 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 D521_0481 92b6e8ec71a36226328fa32eaee180ba 487 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 424 1.4E-147 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 D521_1268 7de4743f62136a0fa0dd29fd47e36233 275 Gene3D G3DSA:1.10.166.10 2 72 3.5E-27 T 14-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 D521_1268 7de4743f62136a0fa0dd29fd47e36233 275 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 6 71 1.3E-25 T 14-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 D521_1268 7de4743f62136a0fa0dd29fd47e36233 275 SUPERFAMILY SSF51161 5 259 2.77E-71 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily D521_1268 7de4743f62136a0fa0dd29fd47e36233 275 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 2 275 56.362 T 14-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 D521_1268 7de4743f62136a0fa0dd29fd47e36233 275 Gene3D G3DSA:2.160.10.10 90 260 2.0E-56 T 14-10-2018 D521_1268 7de4743f62136a0fa0dd29fd47e36233 275 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 178 212 9.1E-14 T 14-10-2018 IPR001451 Hexapeptide repeat D521_1268 7de4743f62136a0fa0dd29fd47e36233 275 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 6 274 1.6E-136 T 14-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 D521_1268 7de4743f62136a0fa0dd29fd47e36233 275 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 137 165 - T 14-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 D521_1268 7de4743f62136a0fa0dd29fd47e36233 275 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 135 169 4.5E-5 T 14-10-2018 IPR001451 Hexapeptide repeat D521_2028 c9c3d764618f97fa3a8b92f881318cf1 94 Gene3D G3DSA:4.10.520.10 1 94 6.9E-33 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 D521_2028 c9c3d764618f97fa3a8b92f881318cf1 94 SUPERFAMILY SSF47729 1 91 8.68E-30 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 D521_2028 c9c3d764618f97fa3a8b92f881318cf1 94 Pfam PF00216 Bacterial DNA-binding protein 1 90 6.0E-30 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_2028 c9c3d764618f97fa3a8b92f881318cf1 94 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 9.0E-15 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_2028 c9c3d764618f97fa3a8b92f881318cf1 94 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 9.0E-15 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_2028 c9c3d764618f97fa3a8b92f881318cf1 94 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 9.0E-15 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_2028 c9c3d764618f97fa3a8b92f881318cf1 94 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 D521_2028 c9c3d764618f97fa3a8b92f881318cf1 94 SMART SM00411 1 90 3.1E-37 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_1053 0c1d30ca972f87896f7f20d82979a556 236 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 52 227 3.4E-53 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 D521_1053 0c1d30ca972f87896f7f20d82979a556 236 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 234 30.032 T 14-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 D521_1053 0c1d30ca972f87896f7f20d82979a556 236 Gene3D G3DSA:3.30.70.260 128 213 1.8E-67 T 14-10-2018 D521_1053 0c1d30ca972f87896f7f20d82979a556 236 SUPERFAMILY SSF75445 129 215 3.92E-18 T 14-10-2018 D521_1053 0c1d30ca972f87896f7f20d82979a556 236 Gene3D G3DSA:3.40.50.1360 20 226 1.8E-67 T 14-10-2018 D521_1053 0c1d30ca972f87896f7f20d82979a556 236 SUPERFAMILY SSF100950 1 142 9.94E-39 T 14-10-2018 IPR037171 NagB/RpiA transferase-like D521_1053 0c1d30ca972f87896f7f20d82979a556 236 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 7 230 2.1E-58 T 14-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 D521_0961 42ed22224205ff643f0f1ea9235f59af 137 Gene3D G3DSA:2.170.150.20 1 137 1.5E-60 T 14-10-2018 D521_0961 42ed22224205ff643f0f1ea9235f59af 137 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 2 128 38.534 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 D521_0961 42ed22224205ff643f0f1ea9235f59af 137 Pfam PF01641 SelR domain 8 127 1.3E-53 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 D521_0961 42ed22224205ff643f0f1ea9235f59af 137 SUPERFAMILY SSF51316 3 130 6.28E-60 T 14-10-2018 IPR011057 Mss4-like superfamily D521_0961 42ed22224205ff643f0f1ea9235f59af 137 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 3 130 8.6E-60 T 14-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 D521_1362 e8d07e169f266062a647048b33a7b584 383 TIGRFAM TIGR04373 egtB_X_signatur: EgtB-related enzyme signature domain 332 381 8.3E-21 T 14-10-2018 IPR030809 EgtB-related enzyme signature domain D521_1362 e8d07e169f266062a647048b33a7b584 383 SUPERFAMILY SSF56436 180 382 5.65E-41 T 14-10-2018 IPR016187 C-type lectin fold D521_1362 e8d07e169f266062a647048b33a7b584 383 SUPERFAMILY SSF109854 17 129 2.01E-7 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes D521_1362 e8d07e169f266062a647048b33a7b584 383 Pfam PF03781 Sulfatase-modifying factor enzyme 1 313 380 3.6E-9 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 D521_1362 e8d07e169f266062a647048b33a7b584 383 Pfam PF03781 Sulfatase-modifying factor enzyme 1 180 301 1.9E-17 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 D521_1362 e8d07e169f266062a647048b33a7b584 383 Gene3D G3DSA:3.90.1580.10 177 305 2.6E-19 T 14-10-2018 D521_1362 e8d07e169f266062a647048b33a7b584 383 Gene3D G3DSA:3.90.1580.10 312 382 5.0E-6 T 14-10-2018 D521_1283 a1b208ce8ec24f68b2d074ca4fc98aee 579 Pfam PF03235 Protein of unknown function DUF262 9 258 4.8E-28 T 14-10-2018 IPR004919 Domain of unknown function DUF262 D521_1837 cf26111e8bceebe91f3c2941fe42e0b8 203 SUPERFAMILY SSF50800 1 200 2.2E-49 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily D521_1837 cf26111e8bceebe91f3c2941fe42e0b8 203 Pfam PF03473 MOSC domain 57 175 1.6E-23 T 14-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 D521_1837 cf26111e8bceebe91f3c2941fe42e0b8 203 Gene3D G3DSA:2.40.33.20 1 203 7.0E-56 T 14-10-2018 D521_1870 1a32a2588afd2cbca09b3a0c26e2cc14 79 Pfam PF02954 Bacterial regulatory protein, Fis family 35 72 1.8E-12 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 D521_1870 1a32a2588afd2cbca09b3a0c26e2cc14 79 PIRSF PIRSF002097 1 78 3.1E-30 T 14-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 D521_1870 1a32a2588afd2cbca09b3a0c26e2cc14 79 PRINTS PR01591 DNA-binding protein FIS signature 6 22 2.8E-7 T 14-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 D521_1870 1a32a2588afd2cbca09b3a0c26e2cc14 79 PRINTS PR01591 DNA-binding protein FIS signature 22 37 2.8E-7 T 14-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 D521_1870 1a32a2588afd2cbca09b3a0c26e2cc14 79 PRINTS PR01591 DNA-binding protein FIS signature 37 49 2.8E-7 T 14-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 D521_1870 1a32a2588afd2cbca09b3a0c26e2cc14 79 Gene3D G3DSA:1.10.10.60 1 77 9.2E-24 T 14-10-2018 D521_1870 1a32a2588afd2cbca09b3a0c26e2cc14 79 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 41 58 2.1E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 D521_1870 1a32a2588afd2cbca09b3a0c26e2cc14 79 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 58 78 2.1E-7 T 14-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 D521_1870 1a32a2588afd2cbca09b3a0c26e2cc14 79 SUPERFAMILY SSF46689 6 77 2.37E-19 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 D521_0119 d6c35da27361b815cd2cb9f11260e09a 395 Pfam PF13609 Gram-negative porin 7 367 1.2E-35 T 14-10-2018 D521_0119 d6c35da27361b815cd2cb9f11260e09a 395 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 98 108 2.2E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 D521_0119 d6c35da27361b815cd2cb9f11260e09a 395 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 346 363 2.2E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 D521_0119 d6c35da27361b815cd2cb9f11260e09a 395 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 57 68 2.2E-6 T 14-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 D521_0119 d6c35da27361b815cd2cb9f11260e09a 395 Gene3D G3DSA:2.40.160.10 11 395 3.8E-61 T 14-10-2018 IPR023614 Porin domain superfamily D521_0119 d6c35da27361b815cd2cb9f11260e09a 395 PRINTS PR00184 Neisseria sp. porin signature 343 367 2.1E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 D521_0119 d6c35da27361b815cd2cb9f11260e09a 395 PRINTS PR00184 Neisseria sp. porin signature 96 115 2.1E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 D521_0119 d6c35da27361b815cd2cb9f11260e09a 395 PRINTS PR00184 Neisseria sp. porin signature 59 84 2.1E-5 T 14-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 D521_0119 d6c35da27361b815cd2cb9f11260e09a 395 SUPERFAMILY SSF56935 17 395 4.71E-52 T 14-10-2018 D521_0030 5dad9cbce215be86b9d1172be697a994 315 SUPERFAMILY SSF53790 31 254 3.27E-71 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 D521_0030 5dad9cbce215be86b9d1172be697a994 315 Gene3D G3DSA:3.30.950.10 140 260 9.2E-32 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 D521_0030 5dad9cbce215be86b9d1172be697a994 315 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 32 256 33.33 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 D521_0030 5dad9cbce215be86b9d1172be697a994 315 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 33 235 1.6E-26 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 D521_0030 5dad9cbce215be86b9d1172be697a994 315 Gene3D G3DSA:3.40.1010.10 21 139 2.8E-42 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 D521_0030 5dad9cbce215be86b9d1172be697a994 315 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 33 306 6.5E-69 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 D521_0030 5dad9cbce215be86b9d1172be697a994 315 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 110 121 - T 14-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 D521_0030 5dad9cbce215be86b9d1172be697a994 315 PIRSF PIRSF005917 23 311 1.2E-90 T 14-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 D521_0554 37db6b866b691e4c64e0d1f1670cead2 227 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 13 226 24.54 T 14-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 D521_0554 37db6b866b691e4c64e0d1f1670cead2 227 Gene3D G3DSA:2.50.20.10 29 225 4.0E-45 T 14-10-2018 D521_0554 37db6b866b691e4c64e0d1f1670cead2 227 SUPERFAMILY SSF89392 31 226 1.69E-34 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX D521_0554 37db6b866b691e4c64e0d1f1670cead2 227 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 38 215 7.6E-31 T 14-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like D521_0034 e8816d402c7b4d60d3d4e6a5faacacfa 219 Pfam PF00583 Acetyltransferase (GNAT) family 72 157 3.5E-9 T 14-10-2018 IPR000182 GNAT domain D521_0034 e8816d402c7b4d60d3d4e6a5faacacfa 219 Gene3D G3DSA:3.40.630.30 19 193 2.4E-23 T 14-10-2018 D521_0034 e8816d402c7b4d60d3d4e6a5faacacfa 219 SUPERFAMILY SSF55729 23 161 4.15E-17 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_0955 3a6edd2947c325cde82b8489fcdcad35 212 Hamap MF_00165 Thymidylate kinase [tmk]. 8 212 28.191 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 D521_0955 3a6edd2947c325cde82b8489fcdcad35 212 SUPERFAMILY SSF52540 7 209 2.03E-49 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0955 3a6edd2947c325cde82b8489fcdcad35 212 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 7 205 4.9E-48 T 14-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 D521_0955 3a6edd2947c325cde82b8489fcdcad35 212 Pfam PF02223 Thymidylate kinase 12 205 8.0E-46 T 14-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 D521_0955 3a6edd2947c325cde82b8489fcdcad35 212 Gene3D G3DSA:3.40.50.300 3 211 3.2E-63 T 14-10-2018 D521_1868 8e9ad245fabb499555b7cb43aa3202f6 385 Gene3D G3DSA:3.50.50.60 7 330 6.8E-61 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1868 8e9ad245fabb499555b7cb43aa3202f6 385 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 282 295 - T 14-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 D521_1868 8e9ad245fabb499555b7cb43aa3202f6 385 Pfam PF01494 FAD binding domain 142 307 2.3E-10 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 D521_1868 8e9ad245fabb499555b7cb43aa3202f6 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 299 1.9E-8 T 14-10-2018 D521_1868 8e9ad245fabb499555b7cb43aa3202f6 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 7 29 1.9E-8 T 14-10-2018 D521_1868 8e9ad245fabb499555b7cb43aa3202f6 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 268 283 1.9E-8 T 14-10-2018 D521_1868 8e9ad245fabb499555b7cb43aa3202f6 385 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 7 381 2.8E-83 T 14-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 D521_1868 8e9ad245fabb499555b7cb43aa3202f6 385 Gene3D G3DSA:3.30.9.50 79 257 6.8E-61 T 14-10-2018 D521_1868 8e9ad245fabb499555b7cb43aa3202f6 385 SUPERFAMILY SSF51905 5 376 2.85E-32 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 Pfam PF16658 Class II release factor RF3, C-terminal domain 327 454 6.3E-42 T 14-10-2018 IPR032090 Peptide chain release factor 3, C-terminal D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 Gene3D G3DSA:3.40.50.300 13 319 3.8E-106 T 14-10-2018 D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 PRINTS PR00315 GTP-binding elongation factor signature 42 53 5.2E-7 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 PRINTS PR00315 GTP-binding elongation factor signature 26 36 5.2E-7 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 PRINTS PR00315 GTP-binding elongation factor signature 6 14 5.2E-7 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 PRINTS PR00315 GTP-binding elongation factor signature 78 87 5.2E-7 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 SUPERFAMILY SSF52540 1 218 4.03E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 Gene3D G3DSA:3.40.50.300 51 215 3.8E-106 T 14-10-2018 D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 Pfam PF00009 Elongation factor Tu GTP binding domain 1 218 1.5E-35 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 SUPERFAMILY SSF54980 332 403 3.38E-14 T 14-10-2018 IPR035647 EF-G domain III/V-like D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 6 89 5.1E-15 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 1 469 9.9E-180 T 14-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 SUPERFAMILY SSF50447 201 331 1.96E-26 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily D521_2037 d2043a0b055e56506dbd813d6181c4f7 480 Gene3D G3DSA:3.30.70.3280 330 469 1.6E-47 T 14-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 Gene3D G3DSA:1.10.150.570 579 631 8.6E-22 T 14-10-2018 D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 Gene3D G3DSA:1.10.10.1800 460 559 1.6E-23 T 14-10-2018 D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 7 630 1.5E-267 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 Pfam PF13932 GidA associated domain 403 625 3.5E-72 T 14-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 SMART SM01228 555 626 4.7E-38 T 14-10-2018 D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 Pfam PF01134 Glucose inhibited division protein A 8 400 3.3E-165 T 14-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 5 633 41.732 T 14-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 369 392 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 Gene3D G3DSA:3.50.50.60 297 459 3.3E-57 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 Gene3D G3DSA:3.50.50.60 1 219 8.7E-86 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 SUPERFAMILY SSF51905 6 262 1.33E-49 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0011 8ded8dacd0d491ebfac98b10ccc37a93 642 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 274 288 - T 14-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 D521_1895 9a2133aa02c5033e4b7c90a71d98a143 506 Gene3D G3DSA:3.40.50.1100 50 149 2.3E-135 T 14-10-2018 D521_1895 9a2133aa02c5033e4b7c90a71d98a143 506 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 4 505 4.2E-246 T 14-10-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 D521_1895 9a2133aa02c5033e4b7c90a71d98a143 506 Gene3D G3DSA:3.40.1020.10 331 506 2.0E-76 T 14-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 D521_1895 9a2133aa02c5033e4b7c90a71d98a143 506 SUPERFAMILY SSF55021 412 505 2.52E-28 T 14-10-2018 D521_1895 9a2133aa02c5033e4b7c90a71d98a143 506 SUPERFAMILY SSF53686 4 359 1.44E-96 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme D521_1895 9a2133aa02c5033e4b7c90a71d98a143 506 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 D521_1895 9a2133aa02c5033e4b7c90a71d98a143 506 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 309 7.8E-79 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme D521_1895 9a2133aa02c5033e4b7c90a71d98a143 506 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 322 411 8.0E-26 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 D521_1895 9a2133aa02c5033e4b7c90a71d98a143 506 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 420 505 4.2E-24 T 14-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 D521_1895 9a2133aa02c5033e4b7c90a71d98a143 506 Gene3D G3DSA:3.40.50.1100 14 320 2.3E-135 T 14-10-2018 D521_1675 2b3d84918f77e4b57410d5bae1cd92a5 427 SUPERFAMILY SSF56954 20 426 5.23E-48 T 14-10-2018 D521_1675 2b3d84918f77e4b57410d5bae1cd92a5 427 Pfam PF02321 Outer membrane efflux protein 254 423 7.0E-10 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_1675 2b3d84918f77e4b57410d5bae1cd92a5 427 Pfam PF02321 Outer membrane efflux protein 49 220 8.8E-19 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_1675 2b3d84918f77e4b57410d5bae1cd92a5 427 Gene3D G3DSA:1.20.1600.10 28 425 1.8E-46 T 14-10-2018 D521_2051 dc6201a7ec77286b4a01ae7bdbdf0249 253 Pfam PF06912 Protein of unknown function (DUF1275) 23 235 4.8E-36 T 14-10-2018 IPR010699 Protein of unknown function DUF1275 D521_0514 116e563cab1e865bd132716879d58f4a 556 SUPERFAMILY SSF57770 142 175 2.75E-12 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_0514 116e563cab1e865bd132716879d58f4a 556 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 542 5.8E-165 T 14-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 D521_0514 116e563cab1e865bd132716879d58f4a 556 Gene3D G3DSA:1.10.730.10 387 545 1.9E-35 T 14-10-2018 D521_0514 116e563cab1e865bd132716879d58f4a 556 PRINTS PR01041 Methionyl-tRNA synthetase signature 10 23 7.1E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 D521_0514 116e563cab1e865bd132716879d58f4a 556 PRINTS PR01041 Methionyl-tRNA synthetase signature 258 269 7.1E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 D521_0514 116e563cab1e865bd132716879d58f4a 556 PRINTS PR01041 Methionyl-tRNA synthetase signature 90 101 7.1E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 D521_0514 116e563cab1e865bd132716879d58f4a 556 PRINTS PR01041 Methionyl-tRNA synthetase signature 391 402 7.1E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 D521_0514 116e563cab1e865bd132716879d58f4a 556 PRINTS PR01041 Methionyl-tRNA synthetase signature 42 56 7.1E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 D521_0514 116e563cab1e865bd132716879d58f4a 556 PRINTS PR01041 Methionyl-tRNA synthetase signature 297 312 7.1E-24 T 14-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 D521_0514 116e563cab1e865bd132716879d58f4a 556 Pfam PF09334 tRNA synthetases class I (M) 9 403 3.3E-146 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0514 116e563cab1e865bd132716879d58f4a 556 Gene3D G3DSA:3.40.50.620 9 386 1.4E-146 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0514 116e563cab1e865bd132716879d58f4a 556 SUPERFAMILY SSF47323 396 553 8.22E-36 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0514 116e563cab1e865bd132716879d58f4a 556 SUPERFAMILY SSF52374 5 393 3.75E-99 T 14-10-2018 D521_0514 116e563cab1e865bd132716879d58f4a 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 26 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0514 116e563cab1e865bd132716879d58f4a 556 Gene3D G3DSA:2.20.28.20 142 176 1.4E-146 T 14-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_0514 116e563cab1e865bd132716879d58f4a 556 Hamap MF_00098 Methionine--tRNA ligase [metG]. 6 554 39.519 T 14-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_0297 d41fe6012f3439afe904dbc88c365eb5 315 SUPERFAMILY SSF56349 124 312 3.53E-56 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_0297 d41fe6012f3439afe904dbc88c365eb5 315 Gene3D G3DSA:1.10.443.10 125 308 9.0E-65 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 D521_0297 d41fe6012f3439afe904dbc88c365eb5 315 SUPERFAMILY SSF47823 21 113 5.49E-27 T 14-10-2018 D521_0297 d41fe6012f3439afe904dbc88c365eb5 315 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 20 314 56.311 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 D521_0297 d41fe6012f3439afe904dbc88c365eb5 315 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 22 314 53.256 T 14-10-2018 IPR023009 Tyrosine recombinase XerC/XerD D521_0297 d41fe6012f3439afe904dbc88c365eb5 315 Gene3D G3DSA:1.10.150.130 20 113 7.1E-17 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal D521_0297 d41fe6012f3439afe904dbc88c365eb5 315 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 25 313 3.4E-105 T 14-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 D521_0297 d41fe6012f3439afe904dbc88c365eb5 315 Pfam PF00589 Phage integrase family 127 299 4.7E-48 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 D521_0297 d41fe6012f3439afe904dbc88c365eb5 315 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 24 103 4.6E-14 T 14-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 D521_0843 583e08bafeba4013e664b3e73bbb6805 133 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 17 129 9.9E-17 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 D521_0843 583e08bafeba4013e664b3e73bbb6805 133 Pfam PF03061 Thioesterase superfamily 48 122 8.8E-12 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 D521_0843 583e08bafeba4013e664b3e73bbb6805 133 SUPERFAMILY SSF54637 10 132 1.1E-29 T 14-10-2018 IPR029069 HotDog domain superfamily D521_0843 583e08bafeba4013e664b3e73bbb6805 133 Gene3D G3DSA:3.10.129.10 4 133 7.9E-39 T 14-10-2018 D521_1796 6a2c39ea4f2f7defd24a823d6534a29b 226 SMART SM00895 88 210 3.9E-13 T 14-10-2018 IPR011711 GntR, C-terminal D521_1796 6a2c39ea4f2f7defd24a823d6534a29b 226 Gene3D G3DSA:1.20.120.530 82 222 2.1E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal D521_1796 6a2c39ea4f2f7defd24a823d6534a29b 226 Pfam PF07729 FCD domain 88 209 4.2E-19 T 14-10-2018 IPR011711 GntR, C-terminal D521_1796 6a2c39ea4f2f7defd24a823d6534a29b 226 SMART SM00345 20 78 6.8E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1796 6a2c39ea4f2f7defd24a823d6534a29b 226 Gene3D G3DSA:1.10.10.10 2 80 2.0E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1796 6a2c39ea4f2f7defd24a823d6534a29b 226 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 78 1.8E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1796 6a2c39ea4f2f7defd24a823d6534a29b 226 SUPERFAMILY SSF46785 14 82 1.63E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1796 6a2c39ea4f2f7defd24a823d6534a29b 226 SUPERFAMILY SSF48008 84 217 7.85E-22 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal D521_0506 3b4bd52b1df138f4e954ddfb5ab66a0f 569 SUPERFAMILY SSF52518 371 552 9.47E-42 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0506 3b4bd52b1df138f4e954ddfb5ab66a0f 569 TIGRFAM TIGR03254 oxalate_oxc: oxalyl-CoA decarboxylase 10 562 3.7E-297 T 14-10-2018 IPR017660 Oxalyl-CoA decarboxylase GO:0008949|GO:0030976|GO:0033611|GO:0046872 KEGG: 00630+4.1.1.8|MetaCyc: PWY-6695|MetaCyc: PWY-6696|MetaCyc: PWY-7985 D521_0506 3b4bd52b1df138f4e954ddfb5ab66a0f 569 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 405 543 7.3E-27 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 D521_0506 3b4bd52b1df138f4e954ddfb5ab66a0f 569 SUPERFAMILY SSF52467 198 357 3.48E-38 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily D521_0506 3b4bd52b1df138f4e954ddfb5ab66a0f 569 Gene3D G3DSA:3.40.50.1220 196 353 6.9E-43 T 14-10-2018 D521_0506 3b4bd52b1df138f4e954ddfb5ab66a0f 569 SUPERFAMILY SSF52518 11 183 1.49E-43 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0506 3b4bd52b1df138f4e954ddfb5ab66a0f 569 Gene3D G3DSA:3.40.50.970 2 195 9.5E-64 T 14-10-2018 D521_0506 3b4bd52b1df138f4e954ddfb5ab66a0f 569 Gene3D G3DSA:3.40.50.970 354 569 6.0E-60 T 14-10-2018 D521_0506 3b4bd52b1df138f4e954ddfb5ab66a0f 569 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 13 180 1.9E-45 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 D521_0506 3b4bd52b1df138f4e954ddfb5ab66a0f 569 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 204 333 5.1E-31 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 D521_0278 9502f29eff787991343649e1e727c379 266 SUPERFAMILY SSF74653 105 266 1.37E-14 T 14-10-2018 D521_0278 9502f29eff787991343649e1e727c379 266 Pfam PF13103 TonB C terminal 179 262 4.0E-16 T 14-10-2018 D521_0278 9502f29eff787991343649e1e727c379 266 TIGRFAM TIGR02794 tolA_full: protein TolA 78 264 5.1E-18 T 14-10-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0016021|GO:0043213 D521_0278 9502f29eff787991343649e1e727c379 266 Gene3D G3DSA:3.30.1150.10 114 266 6.0E-13 T 14-10-2018 D521_0278 9502f29eff787991343649e1e727c379 266 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 205 264 3.6E-7 T 14-10-2018 IPR006260 TonB/TolA, C-terminal D521_1715 1ad39899c63e2a15ec7fc31f16b930f6 397 Gene3D G3DSA:3.90.1150.10 21 385 8.1E-128 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_1715 1ad39899c63e2a15ec7fc31f16b930f6 397 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 218 255 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_1715 1ad39899c63e2a15ec7fc31f16b930f6 397 SUPERFAMILY SSF53383 12 395 2.23E-113 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_1715 1ad39899c63e2a15ec7fc31f16b930f6 397 Gene3D G3DSA:3.40.640.10 56 299 8.1E-128 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_1715 1ad39899c63e2a15ec7fc31f16b930f6 397 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 12 396 64.981 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 D521_1715 1ad39899c63e2a15ec7fc31f16b930f6 397 PIRSF PIRSF000521 160 396 2.0E-33 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_1715 1ad39899c63e2a15ec7fc31f16b930f6 397 PIRSF PIRSF000521 21 171 2.0E-11 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_1715 1ad39899c63e2a15ec7fc31f16b930f6 397 Pfam PF00202 Aminotransferase class-III 22 392 3.1E-104 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_1715 1ad39899c63e2a15ec7fc31f16b930f6 397 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 17 393 3.3E-124 T 14-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 D521_1435 219246c85bd8c254091a0bdfe5706072 319 Gene3D G3DSA:3.90.226.10 73 273 1.8E-64 T 14-10-2018 D521_1435 219246c85bd8c254091a0bdfe5706072 319 Pfam PF01343 Peptidase family S49 136 276 4.1E-37 T 14-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 D521_1435 219246c85bd8c254091a0bdfe5706072 319 Gene3D G3DSA:3.40.1750.20 173 239 1.8E-64 T 14-10-2018 D521_1435 219246c85bd8c254091a0bdfe5706072 319 SUPERFAMILY SSF52096 59 269 3.79E-38 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_1565 3684d0be10be11c17b98d7313ce38627 268 Gene3D G3DSA:3.40.50.150 33 265 1.7E-42 T 14-10-2018 D521_1565 3684d0be10be11c17b98d7313ce38627 268 SUPERFAMILY SSF53335 22 238 9.36E-40 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1565 3684d0be10be11c17b98d7313ce38627 268 Pfam PF01564 Spermine/spermidine synthase domain 63 185 2.5E-10 T 14-10-2018 D521_1850 320674e5f14e2d7a88a6736109ddc822 633 SUPERFAMILY SSF110942 521 632 3.27E-37 T 14-10-2018 IPR037196 HSP90, C-terminal domain D521_1850 320674e5f14e2d7a88a6736109ddc822 633 Hamap MF_00505 Chaperone protein HtpG [htpG]. 4 632 32.729 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 D521_1850 320674e5f14e2d7a88a6736109ddc822 633 Gene3D G3DSA:3.30.565.10 2 231 1.7E-77 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1850 320674e5f14e2d7a88a6736109ddc822 633 Pfam PF00183 Hsp90 protein 217 631 2.1E-132 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 D521_1850 320674e5f14e2d7a88a6736109ddc822 633 SMART SM00387 29 186 5.6E-9 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_1850 320674e5f14e2d7a88a6736109ddc822 633 SUPERFAMILY SSF55874 7 218 2.23E-67 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1850 320674e5f14e2d7a88a6736109ddc822 633 Gene3D G3DSA:1.20.120.790 502 633 2.1E-46 T 14-10-2018 IPR037196 HSP90, C-terminal domain D521_1850 320674e5f14e2d7a88a6736109ddc822 633 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 27 36 - T 14-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 D521_1850 320674e5f14e2d7a88a6736109ddc822 633 Gene3D G3DSA:3.40.50.11260 407 496 1.4E-32 T 14-10-2018 D521_1850 320674e5f14e2d7a88a6736109ddc822 633 PRINTS PR00775 90kDa heat shock protein signature 95 112 7.9E-63 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal D521_1850 320674e5f14e2d7a88a6736109ddc822 633 PRINTS PR00775 90kDa heat shock protein signature 77 94 7.9E-63 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal D521_1850 320674e5f14e2d7a88a6736109ddc822 633 PRINTS PR00775 90kDa heat shock protein signature 28 50 7.9E-63 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal D521_1850 320674e5f14e2d7a88a6736109ddc822 633 PRINTS PR00775 90kDa heat shock protein signature 174 191 7.9E-63 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal D521_1850 320674e5f14e2d7a88a6736109ddc822 633 PRINTS PR00775 90kDa heat shock protein signature 7 27 7.9E-63 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal D521_1850 320674e5f14e2d7a88a6736109ddc822 633 PRINTS PR00775 90kDa heat shock protein signature 122 144 7.9E-63 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal D521_1850 320674e5f14e2d7a88a6736109ddc822 633 PRINTS PR00775 90kDa heat shock protein signature 192 210 7.9E-63 T 14-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal D521_1850 320674e5f14e2d7a88a6736109ddc822 633 SUPERFAMILY SSF54211 237 495 5.01E-96 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_1850 320674e5f14e2d7a88a6736109ddc822 633 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 184 3.9E-13 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_1850 320674e5f14e2d7a88a6736109ddc822 633 Gene3D G3DSA:3.30.230.80 235 406 3.2E-66 T 14-10-2018 D521_1850 320674e5f14e2d7a88a6736109ddc822 633 PIRSF PIRSF002583 3 633 1.4E-217 T 14-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 D521_0319 6caedeea76576ac82f61c5ac4d83f1e2 614 Pfam PF01261 Xylose isomerase-like TIM barrel 453 559 4.3E-7 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain D521_0319 6caedeea76576ac82f61c5ac4d83f1e2 614 Gene3D G3DSA:3.90.1210.10 277 335 7.8E-6 T 14-10-2018 D521_0319 6caedeea76576ac82f61c5ac4d83f1e2 614 Gene3D G3DSA:3.20.20.150 360 591 4.3E-13 T 14-10-2018 D521_0319 6caedeea76576ac82f61c5ac4d83f1e2 614 Gene3D G3DSA:3.20.20.70 2 276 4.3E-64 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0319 6caedeea76576ac82f61c5ac4d83f1e2 614 SUPERFAMILY SSF51569 9 261 1.34E-53 T 14-10-2018 D521_0319 6caedeea76576ac82f61c5ac4d83f1e2 614 SUPERFAMILY SSF51658 395 566 1.65E-9 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily D521_0319 6caedeea76576ac82f61c5ac4d83f1e2 614 SUPERFAMILY SSF51269 268 333 2.51E-8 T 14-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 D521_0319 6caedeea76576ac82f61c5ac4d83f1e2 614 Pfam PF03102 NeuB family 30 251 2.5E-44 T 14-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 D521_1800 1153d4352f80aba26bfbf034c06be559 506 SUPERFAMILY SSF53720 9 491 1.83E-151 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 D521_1800 1153d4352f80aba26bfbf034c06be559 506 Gene3D G3DSA:3.40.309.10 258 459 3.6E-152 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 D521_1800 1153d4352f80aba26bfbf034c06be559 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 283 294 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 D521_1800 1153d4352f80aba26bfbf034c06be559 506 Gene3D G3DSA:3.40.605.10 32 467 3.6E-152 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 D521_1800 1153d4352f80aba26bfbf034c06be559 506 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 14 490 4.7E-208 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 D521_1800 1153d4352f80aba26bfbf034c06be559 506 Pfam PF00171 Aldehyde dehydrogenase family 25 486 2.3E-143 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 D521_0897 7e79150d8efa825ca7aaa51232b85379 815 SUPERFAMILY SSF56719 81 555 4.45E-149 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 D521_0897 7e79150d8efa825ca7aaa51232b85379 815 Gene3D G3DSA:3.90.199.10 82 555 9.8E-187 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 D521_0897 7e79150d8efa825ca7aaa51232b85379 815 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 54 814 32.569 T 14-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_0897 7e79150d8efa825ca7aaa51232b85379 815 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 82 536 1.4E-131 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0897 7e79150d8efa825ca7aaa51232b85379 815 SUPERFAMILY SSF101904 568 809 5.1E-43 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal D521_0897 7e79150d8efa825ca7aaa51232b85379 815 SMART SM00434 61 533 8.0E-217 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0897 7e79150d8efa825ca7aaa51232b85379 815 Gene3D G3DSA:1.10.268.10 441 526 9.8E-187 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 D521_0897 7e79150d8efa825ca7aaa51232b85379 815 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 61 803 8.7E-223 T 14-10-2018 D521_0897 7e79150d8efa825ca7aaa51232b85379 815 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 721 763 8.9E-6 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 D521_0897 7e79150d8efa825ca7aaa51232b85379 815 Gene3D G3DSA:2.120.10.90 569 803 2.6E-18 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal D521_0897 7e79150d8efa825ca7aaa51232b85379 815 Gene3D G3DSA:3.30.1360.40 287 403 9.8E-187 T 14-10-2018 D521_0501 10f7014acc991bb7db4191465e36619c 253 SUPERFAMILY SSF52540 3 229 1.89E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0501 10f7014acc991bb7db4191465e36619c 253 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0501 10f7014acc991bb7db4191465e36619c 253 SMART SM00382 25 215 2.6E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0501 10f7014acc991bb7db4191465e36619c 253 Pfam PF00005 ABC transporter 16 167 9.9E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0501 10f7014acc991bb7db4191465e36619c 253 Gene3D G3DSA:3.40.50.300 1 245 6.7E-57 T 14-10-2018 D521_0425 1a0f8bd7949ae9b7bf356d1c91307cfe 1257 SUPERFAMILY SSF53706 15 1085 0.0 T 14-10-2018 D521_0425 1a0f8bd7949ae9b7bf356d1c91307cfe 1257 Gene3D G3DSA:3.40.50.12440 44 1257 0.0 T 14-10-2018 D521_0425 1a0f8bd7949ae9b7bf356d1c91307cfe 1257 SMART SM00926 43 105 6.4E-7 T 14-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0425 1a0f8bd7949ae9b7bf356d1c91307cfe 1257 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 790 807 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 D521_0425 1a0f8bd7949ae9b7bf356d1c91307cfe 1257 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 6.3E-18 T 14-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 D521_0425 1a0f8bd7949ae9b7bf356d1c91307cfe 1257 SUPERFAMILY SSF50692 1092 1248 1.99E-47 T 14-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily D521_0425 1a0f8bd7949ae9b7bf356d1c91307cfe 1257 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1248 0.0 T 14-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 D521_0425 1a0f8bd7949ae9b7bf356d1c91307cfe 1257 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1138 1165 - T 14-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 D521_0425 1a0f8bd7949ae9b7bf356d1c91307cfe 1257 Pfam PF00384 Molybdopterin oxidoreductase 108 846 2.4E-162 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0425 1a0f8bd7949ae9b7bf356d1c91307cfe 1257 Pfam PF01568 Molydopterin dinucleotide binding domain 1100 1215 5.8E-23 T 14-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 D521_1513 9e19c0dc7aae7343e14961cb73f4bb84 316 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 7 312 1.6E-90 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family D521_1513 9e19c0dc7aae7343e14961cb73f4bb84 316 Pfam PF16868 NMT1-like family 25 311 3.4E-77 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family D521_1513 9e19c0dc7aae7343e14961cb73f4bb84 316 Gene3D G3DSA:3.40.190.10 108 248 6.6E-94 T 14-10-2018 D521_1513 9e19c0dc7aae7343e14961cb73f4bb84 316 SUPERFAMILY SSF53850 21 312 8.82E-70 T 14-10-2018 D521_1513 9e19c0dc7aae7343e14961cb73f4bb84 316 Gene3D G3DSA:3.40.190.10 25 311 6.6E-94 T 14-10-2018 D521_0844 92dbd05022f8c9c74798c2db5dba6430 94 Gene3D G3DSA:4.10.430.10 51 94 9.9E-13 T 14-10-2018 IPR037150 Histone-like protein H-NS, C-terminal domain superfamily GO:0003677 D521_0844 92dbd05022f8c9c74798c2db5dba6430 94 Pfam PF00816 H-NS histone family 6 85 6.3E-22 T 14-10-2018 IPR001801 Histone-like protein H-NS GO:0003677|GO:0005622|GO:0006355 D521_0844 92dbd05022f8c9c74798c2db5dba6430 94 SMART SM00528 55 94 1.6E-7 T 14-10-2018 IPR027444 Histone-like protein H-NS, C-terminal domain GO:0003677 D521_0844 92dbd05022f8c9c74798c2db5dba6430 94 SUPERFAMILY SSF81273 59 94 1.96E-9 T 14-10-2018 D521_0612 d559ac697e5e8f662472bd798245f3d4 122 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 7 111 3.5E-23 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 D521_0612 d559ac697e5e8f662472bd798245f3d4 122 SUPERFAMILY SSF89919 4 111 1.28E-29 T 14-10-2018 IPR023799 Ribosome-binding factor A domain superfamily D521_0612 d559ac697e5e8f662472bd798245f3d4 122 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 7 109 23.959 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 D521_0612 d559ac697e5e8f662472bd798245f3d4 122 Gene3D G3DSA:3.30.300.20 2 103 2.0E-28 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta D521_0612 d559ac697e5e8f662472bd798245f3d4 122 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 11 96 3.0E-35 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 D521_0612 d559ac697e5e8f662472bd798245f3d4 122 Pfam PF02033 Ribosome-binding factor A 8 109 3.2E-27 T 14-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 D521_1574 57e2ee3cbba6a249bddff6c2fa60461f 568 Gene3D G3DSA:3.10.310.70 104 230 1.1E-122 T 14-10-2018 D521_1574 57e2ee3cbba6a249bddff6c2fa60461f 568 Gene3D G3DSA:2.30.40.10 31 542 1.1E-122 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 D521_1574 57e2ee3cbba6a249bddff6c2fa60461f 568 Gene3D G3DSA:3.20.20.140 85 525 1.1E-122 T 14-10-2018 D521_1574 57e2ee3cbba6a249bddff6c2fa60461f 568 SUPERFAMILY SSF51338 21 565 5.08E-23 T 14-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 D521_1574 57e2ee3cbba6a249bddff6c2fa60461f 568 SUPERFAMILY SSF51556 84 526 3.28E-23 T 14-10-2018 IPR032466 Metal-dependent hydrolase D521_1574 57e2ee3cbba6a249bddff6c2fa60461f 568 Pfam PF07969 Amidohydrolase family 73 565 1.2E-83 T 14-10-2018 IPR013108 Amidohydrolase 3 D521_0203 a488064316d81b2934c5743d68095e8e 460 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 9.3E-17 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 D521_0203 a488064316d81b2934c5743d68095e8e 460 SUPERFAMILY SSF47446 331 433 1.37E-33 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 D521_0203 a488064316d81b2934c5743d68095e8e 460 SMART SM00962 103 299 3.7E-113 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 D521_0203 a488064316d81b2934c5743d68095e8e 460 SMART SM00963 1 86 1.5E-28 T 14-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 D521_0203 a488064316d81b2934c5743d68095e8e 460 Gene3D G3DSA:1.10.260.30 330 455 6.0E-41 T 14-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 D521_0203 a488064316d81b2934c5743d68095e8e 460 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 432 1.4E-167 T 14-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 D521_0203 a488064316d81b2934c5743d68095e8e 460 Pfam PF00448 SRP54-type protein, GTPase domain 103 299 1.8E-71 T 14-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 D521_0203 a488064316d81b2934c5743d68095e8e 460 Gene3D G3DSA:1.20.120.140 4 309 6.9E-118 T 14-10-2018 D521_0203 a488064316d81b2934c5743d68095e8e 460 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 458 32.583 T 14-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 D521_0203 a488064316d81b2934c5743d68095e8e 460 Gene3D G3DSA:3.40.50.300 90 288 6.9E-118 T 14-10-2018 D521_0203 a488064316d81b2934c5743d68095e8e 460 SUPERFAMILY SSF52540 42 357 1.59E-50 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0203 a488064316d81b2934c5743d68095e8e 460 SMART SM00382 102 304 1.3E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0203 a488064316d81b2934c5743d68095e8e 460 Pfam PF02978 Signal peptide binding domain 331 430 1.3E-31 T 14-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 Gene3D G3DSA:3.30.1330.10 226 429 6.5E-40 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 SUPERFAMILY SSF109736 166 232 1.83E-19 T 14-10-2018 D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 SUPERFAMILY SSF56042 438 669 1.64E-49 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 4 1344 20.605 T 14-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 Gene3D G3DSA:3.90.650.10 833 1025 7.2E-29 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 Gene3D G3DSA:3.90.650.10 430 610 4.6E-55 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 Pfam PF02769 AIR synthase related protein, C-terminal domain 440 597 2.8E-29 T 14-10-2018 IPR010918 PurM-like, C-terminal domain D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 Pfam PF02769 AIR synthase related protein, C-terminal domain 865 995 4.1E-9 T 14-10-2018 IPR010918 PurM-like, C-terminal domain D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 SUPERFAMILY SSF55326 233 436 2.72E-58 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 8 1342 0.0 T 14-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 SUPERFAMILY SSF55326 633 830 7.85E-66 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 SUPERFAMILY SSF82697 5 162 5.75E-37 T 14-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 Gene3D G3DSA:1.10.8.750 166 225 1.9E-22 T 14-10-2018 D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 SMART SM01211 1084 1343 2.7E-148 T 14-10-2018 D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1084 1342 2.7E-105 T 14-10-2018 D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 Gene3D G3DSA:3.30.1330.10 628 823 2.2E-24 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 SUPERFAMILY SSF56042 845 1077 5.98E-45 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 SUPERFAMILY SSF52317 1081 1343 2.79E-94 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_0936 a834bfee2c4ebfca88d2bfebf3e54f0b 1344 Gene3D G3DSA:3.40.50.880 1026 1344 5.0E-132 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_0448 e63ff3f0947ac9733bb4cb94bb1dc3d6 686 Gene3D G3DSA:1.10.8.80 259 370 3.8E-65 T 14-10-2018 D521_0448 e63ff3f0947ac9733bb4cb94bb1dc3d6 686 Pfam PF10412 Type IV secretion-system coupling protein DNA-binding domain 186 558 4.3E-55 T 14-10-2018 IPR019476 Type IV secretion system coupling protein TraD, DNA-binding domain D521_0448 e63ff3f0947ac9733bb4cb94bb1dc3d6 686 Gene3D G3DSA:3.40.50.300 165 562 3.8E-65 T 14-10-2018 D521_0448 e63ff3f0947ac9733bb4cb94bb1dc3d6 686 SUPERFAMILY SSF52540 197 553 1.03E-32 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR00701 60kDa inner membrane protein signature 172 192 1.5E-66 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR00701 60kDa inner membrane protein signature 480 502 1.5E-66 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR00701 60kDa inner membrane protein signature 516 539 1.5E-66 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR00701 60kDa inner membrane protein signature 433 456 1.5E-66 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR00701 60kDa inner membrane protein signature 269 284 1.5E-66 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR00701 60kDa inner membrane protein signature 2 23 1.5E-66 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR00701 60kDa inner membrane protein signature 342 362 1.5E-66 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR00701 60kDa inner membrane protein signature 88 109 1.5E-66 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 Pfam PF02096 60Kd inner membrane protein 372 549 3.1E-60 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 552 23.743 T 14-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 Gene3D G3DSA:2.70.98.90 80 351 8.7E-66 T 14-10-2018 IPR038221 YidC, periplasmic domain superfamily D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR01900 YidC translocation/secretion protein signature 357 373 4.1E-25 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR01900 YidC translocation/secretion protein signature 486 501 4.1E-25 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 PRINTS PR01900 YidC translocation/secretion protein signature 505 529 4.1E-25 T 14-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 D521_2116 ef4a333907aacf51354f8edf07760e54 558 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 371 549 1.1E-70 T 14-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_2116 ef4a333907aacf51354f8edf07760e54 558 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 370 3.5E-86 T 14-10-2018 IPR028053 Membrane insertase YidC, N-terminal D521_2116 ef4a333907aacf51354f8edf07760e54 558 Pfam PF14849 YidC periplasmic domain 84 361 1.1E-63 T 14-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain D521_1466 444d639d8bfe589003c5f08eafbb3b5c 422 Gene3D G3DSA:1.10.8.350 52 243 6.3E-85 T 14-10-2018 D521_1466 444d639d8bfe589003c5f08eafbb3b5c 422 SUPERFAMILY SSF53955 50 381 5.06E-62 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily D521_1466 444d639d8bfe589003c5f08eafbb3b5c 422 Pfam PF13406 Transglycosylase SLT domain 48 379 4.4E-86 T 14-10-2018 IPR031304 Transglycosylase SLT domain 2 D521_1466 444d639d8bfe589003c5f08eafbb3b5c 422 Gene3D G3DSA:1.10.530.10 90 380 6.3E-85 T 14-10-2018 D521_1466 444d639d8bfe589003c5f08eafbb3b5c 422 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 54 381 1.3E-84 T 14-10-2018 IPR011757 Lytic transglycosylase MltB D521_1750 796230e01c57ffc212639afa427e2326 376 Pfam PF00684 DnaJ central domain 149 209 2.9E-14 T 14-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 D521_1750 796230e01c57ffc212639afa427e2326 376 Gene3D G3DSA:1.10.287.110 3 115 2.7E-37 T 14-10-2018 IPR036869 Chaperone J-domain superfamily D521_1750 796230e01c57ffc212639afa427e2326 376 SUPERFAMILY SSF49493 117 263 4.19E-19 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 D521_1750 796230e01c57ffc212639afa427e2326 376 Gene3D G3DSA:2.60.260.20 257 365 1.9E-29 T 14-10-2018 D521_1750 796230e01c57ffc212639afa427e2326 376 Pfam PF01556 DnaJ C terminal domain 123 335 1.7E-40 T 14-10-2018 IPR002939 Chaperone DnaJ, C-terminal D521_1750 796230e01c57ffc212639afa427e2326 376 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 7 351 2.8E-135 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 D521_1750 796230e01c57ffc212639afa427e2326 376 SUPERFAMILY SSF57938 136 213 4.45E-21 T 14-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily D521_1750 796230e01c57ffc212639afa427e2326 376 ProSitePatterns PS00636 Nt-dnaJ domain signature. 49 68 - T 14-10-2018 IPR018253 DnaJ domain, conserved site D521_1750 796230e01c57ffc212639afa427e2326 376 PRINTS PR00625 DnaJ domain signature 9 27 2.3E-31 T 14-10-2018 IPR001623 DnaJ domain D521_1750 796230e01c57ffc212639afa427e2326 376 PRINTS PR00625 DnaJ domain signature 27 42 2.3E-31 T 14-10-2018 IPR001623 DnaJ domain D521_1750 796230e01c57ffc212639afa427e2326 376 PRINTS PR00625 DnaJ domain signature 64 83 2.3E-31 T 14-10-2018 IPR001623 DnaJ domain D521_1750 796230e01c57ffc212639afa427e2326 376 PRINTS PR00625 DnaJ domain signature 44 64 2.3E-31 T 14-10-2018 IPR001623 DnaJ domain D521_1750 796230e01c57ffc212639afa427e2326 376 SMART SM00271 6 64 3.0E-30 T 14-10-2018 IPR001623 DnaJ domain D521_1750 796230e01c57ffc212639afa427e2326 376 Pfam PF00226 DnaJ domain 7 69 2.0E-27 T 14-10-2018 IPR001623 DnaJ domain D521_1750 796230e01c57ffc212639afa427e2326 376 Gene3D G3DSA:2.10.230.10 141 211 6.1E-24 T 14-10-2018 D521_1750 796230e01c57ffc212639afa427e2326 376 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 4 374 40.725 T 14-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 D521_1750 796230e01c57ffc212639afa427e2326 376 SUPERFAMILY SSF46565 4 111 2.09E-36 T 14-10-2018 IPR036869 Chaperone J-domain superfamily D521_1750 796230e01c57ffc212639afa427e2326 376 SUPERFAMILY SSF49493 260 346 1.57E-22 T 14-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 17 782 24.306 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Gene3D G3DSA:3.10.20.310 104 184 7.3E-17 T 14-10-2018 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Pfam PF07244 Surface antigen variable number repeat 104 184 3.6E-12 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Pfam PF07244 Surface antigen variable number repeat 188 275 2.3E-19 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Pfam PF07244 Surface antigen variable number repeat 279 356 1.6E-11 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Pfam PF07244 Surface antigen variable number repeat 37 101 2.1E-6 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Pfam PF07244 Surface antigen variable number repeat 359 433 1.8E-13 T 14-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 D521_1253 693bf4e0838d59f650fa21d273f66179 782 PIRSF PIRSF006076 4 782 2.7E-239 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Gene3D G3DSA:3.10.20.310 29 103 1.9E-23 T 14-10-2018 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Gene3D G3DSA:2.40.160.50 437 782 5.7E-91 T 14-10-2018 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Gene3D G3DSA:3.10.20.310 360 436 1.2E-24 T 14-10-2018 D521_1253 693bf4e0838d59f650fa21d273f66179 782 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 36 782 3.4E-249 T 14-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Gene3D G3DSA:3.10.20.310 277 358 3.2E-16 T 14-10-2018 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Gene3D G3DSA:3.10.20.310 187 276 6.5E-24 T 14-10-2018 D521_1253 693bf4e0838d59f650fa21d273f66179 782 Pfam PF01103 Surface antigen 460 782 1.1E-61 T 14-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 D521_0132 45be80ac657b5da4ebed0220919e3ee2 102 Gene3D G3DSA:3.40.30.10 6 101 2.4E-34 T 14-10-2018 D521_0132 45be80ac657b5da4ebed0220919e3ee2 102 PIRSF PIRSF005894 1 102 3.6E-48 T 14-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 D521_0132 45be80ac657b5da4ebed0220919e3ee2 102 Pfam PF00462 Glutaredoxin 16 81 4.7E-19 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 D521_0132 45be80ac657b5da4ebed0220919e3ee2 102 SUPERFAMILY SSF52833 1 101 9.27E-34 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0132 45be80ac657b5da4ebed0220919e3ee2 102 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 101 3.8E-46 T 14-10-2018 IPR004480 Monothiol glutaredoxin-related D521_1808 fd5bbfda6421a45a9203e002ed8a2b81 164 SMART SM01001 5 156 1.1E-92 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 D521_1808 fd5bbfda6421a45a9203e002ed8a2b81 164 Pfam PF00731 AIR carboxylase 7 154 1.6E-59 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 D521_1808 fd5bbfda6421a45a9203e002ed8a2b81 164 SUPERFAMILY SSF52255 6 160 8.24E-62 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 D521_1808 fd5bbfda6421a45a9203e002ed8a2b81 164 Gene3D G3DSA:3.40.50.7700 1 164 1.6E-69 T 14-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 D521_1808 fd5bbfda6421a45a9203e002ed8a2b81 164 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 7 156 5.5E-60 T 14-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 D521_1808 fd5bbfda6421a45a9203e002ed8a2b81 164 PIRSF PIRSF001338 2 161 5.9E-63 T 14-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 D521_1808 fd5bbfda6421a45a9203e002ed8a2b81 164 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 7 160 30.011 T 14-10-2018 IPR033747 Class I PurE D521_0367 6c90c6e2fe6b8bd03fa34c4cddb8a574 115 Gene3D G3DSA:3.10.50.40 1 115 3.7E-44 T 14-10-2018 D521_0367 6c90c6e2fe6b8bd03fa34c4cddb8a574 115 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 15 111 1.5E-34 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain D521_0367 6c90c6e2fe6b8bd03fa34c4cddb8a574 115 SUPERFAMILY SSF54534 2 114 1.55E-40 T 14-10-2018 D521_1616 12b478ce7bee9820c5dff94b53c49c7c 328 Gene3D G3DSA:1.10.10.60 210 326 3.8E-27 T 14-10-2018 D521_1616 12b478ce7bee9820c5dff94b53c49c7c 328 Pfam PF12833 Helix-turn-helix domain 239 316 3.1E-21 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 D521_1616 12b478ce7bee9820c5dff94b53c49c7c 328 SUPERFAMILY SSF46689 217 266 3.99E-9 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 D521_1616 12b478ce7bee9820c5dff94b53c49c7c 328 SMART SM00342 232 315 6.7E-29 T 14-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 D521_1616 12b478ce7bee9820c5dff94b53c49c7c 328 SUPERFAMILY SSF46689 269 319 1.15E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 D521_1616 12b478ce7bee9820c5dff94b53c49c7c 328 Gene3D G3DSA:3.40.50.880 1 205 2.5E-58 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_1616 12b478ce7bee9820c5dff94b53c49c7c 328 SUPERFAMILY SSF52317 5 197 3.7E-48 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_1616 12b478ce7bee9820c5dff94b53c49c7c 328 Pfam PF01965 DJ-1/PfpI family 6 176 5.6E-24 T 14-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 D521_1356 5b85fa41e11b6d1706e53fad79dafe08 230 Pfam PF14697 4Fe-4S dicluster domain 90 144 2.1E-17 T 14-10-2018 D521_1356 5b85fa41e11b6d1706e53fad79dafe08 230 PIRSF PIRSF005784 1 170 1.9E-53 T 14-10-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 D521_1356 5b85fa41e11b6d1706e53fad79dafe08 230 PIRSF PIRSF005784 184 223 230.0 T 14-10-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 D521_1356 5b85fa41e11b6d1706e53fad79dafe08 230 SUPERFAMILY SSF54862 12 148 2.71E-27 T 14-10-2018 D521_1356 5b85fa41e11b6d1706e53fad79dafe08 230 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 5 158 3.8E-59 T 14-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 D521_1356 5b85fa41e11b6d1706e53fad79dafe08 230 Pfam PF04060 Putative Fe-S cluster 17 49 7.8E-13 T 14-10-2018 IPR007202 4Fe-4S domain GO:0051536 D521_1356 5b85fa41e11b6d1706e53fad79dafe08 230 Gene3D G3DSA:3.30.70.20 72 155 3.7E-18 T 14-10-2018 D521_1356 5b85fa41e11b6d1706e53fad79dafe08 230 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 97 108 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1356 5b85fa41e11b6d1706e53fad79dafe08 230 Gene3D G3DSA:3.20.20.20 10 71 5.4E-12 T 14-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 D521_1356 5b85fa41e11b6d1706e53fad79dafe08 230 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 127 138 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1346 c05d1d269e9052402d8e97f4a7c060bd 112 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 13 91 5.5E-13 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 D521_1346 c05d1d269e9052402d8e97f4a7c060bd 112 Gene3D G3DSA:3.10.20.30 1 112 6.5E-35 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_1346 c05d1d269e9052402d8e97f4a7c060bd 112 SUPERFAMILY SSF54292 5 108 1.04E-30 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 D521_1346 c05d1d269e9052402d8e97f4a7c060bd 112 TIGRFAM TIGR02007 fdx_isc: ferredoxin, 2Fe-2S type, ISC system 3 111 6.5E-55 T 14-10-2018 IPR011536 Ferredoxin 2Fe-2S type, proteobacteria GO:0009055|GO:0051537 D521_1346 c05d1d269e9052402d8e97f4a7c060bd 112 PRINTS PR00355 Adrenodoxin signature 83 91 3.9E-8 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 D521_1346 c05d1d269e9052402d8e97f4a7c060bd 112 PRINTS PR00355 Adrenodoxin signature 60 74 3.9E-8 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 D521_1346 c05d1d269e9052402d8e97f4a7c060bd 112 PRINTS PR00355 Adrenodoxin signature 42 52 3.9E-8 T 14-10-2018 IPR001055 Adrenodoxin GO:0009055|GO:0051537 Reactome: R-HSA-1362409|Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 D521_0169 b1a8330e40784167208c643b07b2c120 423 Pfam PF01098 Cell cycle protein 53 415 1.3E-97 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0169 b1a8330e40784167208c643b07b2c120 423 Hamap MF_00913 Probable peptidoglycan glycosyltransferase FtsW [ftsW]. 49 422 40.532 T 14-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0169 b1a8330e40784167208c643b07b2c120 423 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 51 413 1.1E-120 T 14-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0570 aadec8abe8687a87ee5d540de70c0753 138 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 4 118 1.9E-9 T 14-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component D521_0570 aadec8abe8687a87ee5d540de70c0753 138 SUPERFAMILY SSF88723 1 119 5.33E-10 T 14-10-2018 IPR029060 PIN-like domain superfamily D521_0570 aadec8abe8687a87ee5d540de70c0753 138 Pfam PF13470 PIN domain 4 114 2.5E-20 T 14-10-2018 IPR002716 PIN domain D521_1308 dbd8620ea880c7d210af402eaf27bcb1 46 SUPERFAMILY SSF47413 1 31 5.62E-6 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 D521_1308 dbd8620ea880c7d210af402eaf27bcb1 46 Gene3D G3DSA:1.10.260.40 1 46 1.2E-9 T 14-10-2018 D521_1746 ce0056f7a1c9601a343bcd895309e100 226 SUPERFAMILY SSF56784 2 219 2.21E-32 T 14-10-2018 IPR036412 HAD-like superfamily D521_1746 ce0056f7a1c9601a343bcd895309e100 226 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 4 209 4.4E-40 T 14-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like D521_1746 ce0056f7a1c9601a343bcd895309e100 226 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 196 4.3E-35 T 14-10-2018 D521_1746 ce0056f7a1c9601a343bcd895309e100 226 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 198 3.6E-21 T 14-10-2018 D521_1746 ce0056f7a1c9601a343bcd895309e100 226 Gene3D G3DSA:3.40.50.1000 4 222 2.8E-72 T 14-10-2018 IPR023214 HAD superfamily D521_1746 ce0056f7a1c9601a343bcd895309e100 226 Gene3D G3DSA:1.20.1440.100 16 89 2.8E-72 T 14-10-2018 D521_1572 1d2a17a7bc6f5b3301b57d8a26d872b3 130 SUPERFAMILY SSF55620 6 116 2.67E-12 T 14-10-2018 D521_1572 1d2a17a7bc6f5b3301b57d8a26d872b3 130 Pfam PF02152 Dihydroneopterin aldolase 7 112 7.4E-14 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 D521_1572 1d2a17a7bc6f5b3301b57d8a26d872b3 130 SMART SM00905 7 118 3.2E-4 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 D521_1572 1d2a17a7bc6f5b3301b57d8a26d872b3 130 Gene3D G3DSA:3.30.1130.10 2 122 5.4E-19 T 14-10-2018 D521_1879 3203d8c91baf59c4760d47bf50a2f6a2 133 Gene3D G3DSA:3.30.230.10 6 133 1.9E-49 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup D521_1879 3203d8c91baf59c4760d47bf50a2f6a2 133 ProSitePatterns PS00360 Ribosomal protein S9 signature. 72 90 - T 14-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 D521_1879 3203d8c91baf59c4760d47bf50a2f6a2 133 SUPERFAMILY SSF54211 9 133 6.07E-45 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_1879 3203d8c91baf59c4760d47bf50a2f6a2 133 Pfam PF00380 Ribosomal protein S9/S16 13 133 1.6E-44 T 14-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 D521_1879 3203d8c91baf59c4760d47bf50a2f6a2 133 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 4 133 30.05 T 14-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid D521_1972 222ca9966ac9ad846e984e950185fa1f 258 SUPERFAMILY SSF51735 11 255 2.73E-54 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1972 222ca9966ac9ad846e984e950185fa1f 258 Pfam PF00106 short chain dehydrogenase 14 198 2.4E-41 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1972 222ca9966ac9ad846e984e950185fa1f 258 Gene3D G3DSA:3.40.50.720 2 253 1.5E-52 T 14-10-2018 D521_1972 222ca9966ac9ad846e984e950185fa1f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.8E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1972 222ca9966ac9ad846e984e950185fa1f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 2.8E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1972 222ca9966ac9ad846e984e950185fa1f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.8E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1972 222ca9966ac9ad846e984e950185fa1f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 2.8E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1972 222ca9966ac9ad846e984e950185fa1f 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.8E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1449 3aa58744d563599d5ac84601d504e9e3 448 Pfam PF01523 Putative modulator of DNA gyrase 30 322 6.9E-59 T 14-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 D521_1449 3aa58744d563599d5ac84601d504e9e3 448 Gene3D G3DSA:3.30.2290.10 3 231 1.4E-79 T 14-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal D521_1449 3aa58744d563599d5ac84601d504e9e3 448 SUPERFAMILY SSF111283 8 448 3.01E-119 T 14-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 D521_0899 3d5c6195909837e396a2f62252af7745 202 Pfam PF12804 MobA-like NTP transferase domain 2 151 1.9E-27 T 14-10-2018 IPR025877 MobA-like NTP transferase D521_0899 3d5c6195909837e396a2f62252af7745 202 SUPERFAMILY SSF53448 2 191 1.02E-23 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0899 3d5c6195909837e396a2f62252af7745 202 Gene3D G3DSA:3.90.550.10 1 198 7.3E-38 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0924 882af1005f08386b0eefb6052adde94a 296 Gene3D G3DSA:3.40.50.1000 12 295 2.2E-64 T 14-10-2018 IPR023214 HAD superfamily D521_0924 882af1005f08386b0eefb6052adde94a 296 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 91 260 1.4E-27 T 14-10-2018 D521_0924 882af1005f08386b0eefb6052adde94a 296 Pfam PF12710 haloacid dehalogenase-like hydrolase 93 260 3.0E-19 T 14-10-2018 D521_0924 882af1005f08386b0eefb6052adde94a 296 SUPERFAMILY SSF56784 87 292 8.0E-43 T 14-10-2018 IPR036412 HAD-like superfamily D521_0924 882af1005f08386b0eefb6052adde94a 296 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 87 289 2.1E-60 T 14-10-2018 D521_0274 f550de26b19f0dd3d1e9f436ca6e26e9 246 SUPERFAMILY SSF52402 19 243 8.82E-62 T 14-10-2018 D521_0274 f550de26b19f0dd3d1e9f436ca6e26e9 246 Pfam PF06508 Queuosine biosynthesis protein QueC 20 235 1.3E-75 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 D521_0274 f550de26b19f0dd3d1e9f436ca6e26e9 246 Gene3D G3DSA:3.40.50.620 18 244 3.5E-71 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0274 f550de26b19f0dd3d1e9f436ca6e26e9 246 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 20 228 1.2E-59 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 D521_0274 f550de26b19f0dd3d1e9f436ca6e26e9 246 PIRSF PIRSF006293 17 246 1.1E-74 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 D521_0274 f550de26b19f0dd3d1e9f436ca6e26e9 246 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 18 241 49.489 T 14-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 D521_0105 2dce8217bf48eb6e93037fa680b9fbbb 208 Gene3D G3DSA:3.40.190.10 94 180 3.6E-69 T 14-10-2018 D521_0105 2dce8217bf48eb6e93037fa680b9fbbb 208 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 2 208 53.221 T 14-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 D521_0105 2dce8217bf48eb6e93037fa680b9fbbb 208 Gene3D G3DSA:3.40.190.10 4 201 3.6E-69 T 14-10-2018 D521_0105 2dce8217bf48eb6e93037fa680b9fbbb 208 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 3 188 2.6E-59 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 D521_0105 2dce8217bf48eb6e93037fa680b9fbbb 208 SUPERFAMILY SSF53850 3 207 1.56E-66 T 14-10-2018 D521_0105 2dce8217bf48eb6e93037fa680b9fbbb 208 Pfam PF01634 ATP phosphoribosyltransferase 52 206 6.2E-49 T 14-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 D521_0105 2dce8217bf48eb6e93037fa680b9fbbb 208 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 147 168 - T 14-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 D521_0109 d2b2518ef06e2154da5a499607b4e8f7 220 Pfam PF00117 Glutamine amidotransferase class-I 7 206 1.2E-18 T 14-10-2018 IPR017926 Glutamine amidotransferase D521_0109 d2b2518ef06e2154da5a499607b4e8f7 220 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 5 217 4.9E-61 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 D521_0109 d2b2518ef06e2154da5a499607b4e8f7 220 PIRSF PIRSF000495 3 220 8.3E-67 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 D521_0109 d2b2518ef06e2154da5a499607b4e8f7 220 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 4 218 34.508 T 14-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 D521_0109 d2b2518ef06e2154da5a499607b4e8f7 220 SUPERFAMILY SSF52317 4 218 2.66E-52 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_0109 d2b2518ef06e2154da5a499607b4e8f7 220 Gene3D G3DSA:3.40.50.880 1 219 3.1E-71 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_0718 fe1786c5d8ea14c986558a3fdf129ddf 309 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 309 5.1E-57 T 14-10-2018 IPR005229 Conserved hypothetical protein CHP00255 D521_0718 fe1786c5d8ea14c986558a3fdf129ddf 309 Pfam PF08340 Domain of unknown function (DUF1732) 225 309 7.0E-33 T 14-10-2018 IPR013551 Domain of unknown function DUF1732 D521_0718 fe1786c5d8ea14c986558a3fdf129ddf 309 Pfam PF03755 YicC-like family, N-terminal region 1 163 1.3E-35 T 14-10-2018 IPR013527 YicC-like, N-terminal D521_0084 ab532511ba54d32f848ae2b7a542709d 240 Gene3D G3DSA:1.10.760.10 58 140 1.2E-26 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0084 ab532511ba54d32f848ae2b7a542709d 240 Gene3D G3DSA:1.10.760.10 147 240 1.7E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0084 ab532511ba54d32f848ae2b7a542709d 240 Pfam PF00034 Cytochrome c 74 141 4.9E-8 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0084 ab532511ba54d32f848ae2b7a542709d 240 Pfam PF00034 Cytochrome c 172 238 8.3E-8 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0084 ab532511ba54d32f848ae2b7a542709d 240 PIRSF PIRSF000005 21 240 5.0E-62 T 14-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 D521_0084 ab532511ba54d32f848ae2b7a542709d 240 SUPERFAMILY SSF46626 152 238 7.48E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0084 ab532511ba54d32f848ae2b7a542709d 240 SUPERFAMILY SSF46626 56 141 3.05E-24 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1830 697e942df04c194f7755af09c4484477 362 Hamap MF_00268 Protein RecA [recA]. 21 346 51.993 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 D521_1830 697e942df04c194f7755af09c4484477 362 Gene3D G3DSA:3.30.250.10 286 359 2.0E-29 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal D521_1830 697e942df04c194f7755af09c4484477 362 SUPERFAMILY SSF54752 285 343 2.22E-22 T 14-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal D521_1830 697e942df04c194f7755af09c4484477 362 SUPERFAMILY SSF52540 19 284 3.04E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1830 697e942df04c194f7755af09c4484477 362 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 20 340 3.7E-172 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 D521_1830 697e942df04c194f7755af09c4484477 362 SMART SM00382 74 245 9.3E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1830 697e942df04c194f7755af09c4484477 362 Pfam PF00154 recA bacterial DNA recombination protein 23 285 2.6E-144 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 D521_1830 697e942df04c194f7755af09c4484477 362 PRINTS PR00142 RecA protein signature 227 255 5.0E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 D521_1830 697e942df04c194f7755af09c4484477 362 PRINTS PR00142 RecA protein signature 110 139 5.0E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 D521_1830 697e942df04c194f7755af09c4484477 362 PRINTS PR00142 RecA protein signature 144 173 5.0E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 D521_1830 697e942df04c194f7755af09c4484477 362 PRINTS PR00142 RecA protein signature 260 289 5.0E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 D521_1830 697e942df04c194f7755af09c4484477 362 PRINTS PR00142 RecA protein signature 314 331 5.0E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 D521_1830 697e942df04c194f7755af09c4484477 362 PRINTS PR00142 RecA protein signature 182 211 5.0E-85 T 14-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 D521_1830 697e942df04c194f7755af09c4484477 362 Gene3D G3DSA:3.40.50.300 43 285 5.5E-82 T 14-10-2018 D521_1830 697e942df04c194f7755af09c4484477 362 ProSitePatterns PS00321 recA signature. 230 238 - T 14-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 D521_1126 b7361c79dfc53d3a56da4cf9b537996b 79 SMART SM00899 1 78 2.7E-19 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 D521_1126 b7361c79dfc53d3a56da4cf9b537996b 79 SUPERFAMILY SSF50037 8 78 2.08E-13 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal D521_1126 b7361c79dfc53d3a56da4cf9b537996b 79 Gene3D G3DSA:2.30.30.90 1 79 3.2E-21 T 14-10-2018 IPR038157 Ferrous iron transporter, core domain D521_1126 b7361c79dfc53d3a56da4cf9b537996b 79 Pfam PF04023 FeoA domain 1 77 2.0E-16 T 14-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 D521_0372 00bc34b7f211c1da1f026e05653d27d1 320 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 7 320 53.672 T 14-10-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 D521_0372 00bc34b7f211c1da1f026e05653d27d1 320 SUPERFAMILY SSF56524 68 316 7.06E-90 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 D521_0372 00bc34b7f211c1da1f026e05653d27d1 320 Pfam PF00174 Oxidoreductase molybdopterin binding domain 98 253 6.2E-30 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 D521_0372 00bc34b7f211c1da1f026e05653d27d1 320 Gene3D G3DSA:3.90.420.10 56 320 2.7E-103 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 Pfam PF13167 GTP-binding GTPase N-terminal 1 85 2.4E-27 T 14-10-2018 IPR025121 GTPase HflX, N-terminal D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 SUPERFAMILY SSF52540 172 338 2.45E-39 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 Gene3D G3DSA:3.40.50.11060 1 112 3.7E-34 T 14-10-2018 D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 Gene3D G3DSA:3.40.50.300 174 347 6.5E-38 T 14-10-2018 D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 Pfam PF16360 GTP-binding GTPase Middle Region 88 167 9.2E-25 T 14-10-2018 IPR032305 GTP-binding protein, middle domain D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 Hamap MF_00900 GTPase HflX [hflX]. 1 355 44.194 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 1 337 1.1E-136 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 242 260 2.3E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 175 195 2.3E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 Pfam PF01926 50S ribosome-binding GTPase 175 293 5.4E-20 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_1070 4a0737f7a8ac4169d07dfa05ae970e4c 387 PIRSF PIRSF006809 1 363 8.2E-134 T 14-10-2018 IPR016496 GTPase HflX GO:0005525 D521_1624 d30b744f8d907c4ac6a9f481bc23fcc6 199 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 26 195 2.5E-31 T 14-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component D521_1624 d30b744f8d907c4ac6a9f481bc23fcc6 199 SUPERFAMILY SSF159594 24 198 2.54E-24 T 14-10-2018 D521_1619 d30b744f8d907c4ac6a9f481bc23fcc6 199 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 26 195 2.5E-31 T 14-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component D521_1619 d30b744f8d907c4ac6a9f481bc23fcc6 199 SUPERFAMILY SSF159594 24 198 2.54E-24 T 14-10-2018 D521_1809 b0e398d96b6f3e4bba7ef7840e4496f3 298 Gene3D G3DSA:3.30.200.20 3 103 8.1E-32 T 14-10-2018 D521_1809 b0e398d96b6f3e4bba7ef7840e4496f3 298 ProSitePatterns PS01057 SAICAR synthetase signature 1. 105 119 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_1809 b0e398d96b6f3e4bba7ef7840e4496f3 298 Pfam PF01259 SAICAR synthetase 15 260 5.8E-104 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_1809 b0e398d96b6f3e4bba7ef7840e4496f3 298 SUPERFAMILY SSF56104 5 296 3.92E-103 T 14-10-2018 D521_1809 b0e398d96b6f3e4bba7ef7840e4496f3 298 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 15 297 2.5E-81 T 14-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 D521_1809 b0e398d96b6f3e4bba7ef7840e4496f3 298 ProSitePatterns PS01058 SAICAR synthetase signature 2. 204 212 - T 14-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_1809 b0e398d96b6f3e4bba7ef7840e4496f3 298 Gene3D G3DSA:3.30.470.20 105 248 4.9E-61 T 14-10-2018 D521_1809 b0e398d96b6f3e4bba7ef7840e4496f3 298 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 12 297 26.35 T 14-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 D521_2014 3389c90b60fa904ffcf934e13d9abd54 218 SUPERFAMILY SSF48498 101 199 1.34E-6 T 14-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily D521_2014 3389c90b60fa904ffcf934e13d9abd54 218 Gene3D G3DSA:1.10.357.10 30 218 7.1E-52 T 14-10-2018 D521_2014 3389c90b60fa904ffcf934e13d9abd54 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 49 79 6.2E-9 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 D521_2014 3389c90b60fa904ffcf934e13d9abd54 218 SUPERFAMILY SSF46689 23 96 1.23E-10 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 D521_0567 c5133580c6d52e292fe1223fd714a47a 67 Pfam PF04102 SlyX 3 67 6.9E-22 T 14-10-2018 IPR007236 SlyX D521_0331 88a066de6c4959b3d84d1871df563ba1 120 SUPERFAMILY SSF53800 1 115 4.06E-28 T 14-10-2018 D521_0331 88a066de6c4959b3d84d1871df563ba1 120 Pfam PF01903 CbiX 9 110 1.1E-22 T 14-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 D521_0331 88a066de6c4959b3d84d1871df563ba1 120 Gene3D G3DSA:3.40.50.1400 1 115 5.2E-26 T 14-10-2018 D521_0616 01cd6fe9d0df811f4efc54cfa85eba80 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 59 2.7E-8 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM D521_0616 01cd6fe9d0df811f4efc54cfa85eba80 84 SUPERFAMILY SSF143120 3 48 7.98E-10 T 14-10-2018 IPR036165 YefM-like superfamily D521_0616 01cd6fe9d0df811f4efc54cfa85eba80 84 Gene3D G3DSA:3.40.1620.10 15 50 1.2E-5 T 14-10-2018 D521_0616 01cd6fe9d0df811f4efc54cfa85eba80 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 6 51 9.4E-6 T 14-10-2018 D521_1370 709d4b102c331fd83d3d9e4031242b6a 188 Gene3D G3DSA:1.10.10.10 1 133 4.2E-18 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1370 709d4b102c331fd83d3d9e4031242b6a 188 SUPERFAMILY SSF46785 4 120 2.46E-16 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1370 709d4b102c331fd83d3d9e4031242b6a 188 Pfam PF02082 Transcriptional regulator 1 83 5.9E-17 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type D521_0414 aad3fd412177f11dc5259a33f7662dcb 89 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 2 74 1.8E-9 T 14-10-2018 IPR000477 Reverse transcriptase domain D521_0414 aad3fd412177f11dc5259a33f7662dcb 89 SUPERFAMILY SSF56672 2 76 7.63E-8 T 14-10-2018 D521_0414 aad3fd412177f11dc5259a33f7662dcb 89 Gene3D G3DSA:3.30.70.270 1 84 4.2E-5 T 14-10-2018 D521_1561 03fce11f31d45359582741bf829e3347 275 Gene3D G3DSA:1.10.287.70 24 236 2.0E-56 T 14-10-2018 D521_1561 03fce11f31d45359582741bf829e3347 275 SUPERFAMILY SSF81324 25 235 2.29E-51 T 14-10-2018 D521_1561 03fce11f31d45359582741bf829e3347 275 PRINTS PR00169 Potassium channel signature 17 45 4.0E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 D521_1561 03fce11f31d45359582741bf829e3347 275 PRINTS PR00169 Potassium channel signature 121 147 4.0E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 D521_1561 03fce11f31d45359582741bf829e3347 275 PRINTS PR00169 Potassium channel signature 150 173 4.0E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 D521_1561 03fce11f31d45359582741bf829e3347 275 PRINTS PR00169 Potassium channel signature 208 234 4.0E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 D521_1561 03fce11f31d45359582741bf829e3347 275 PRINTS PR00169 Potassium channel signature 59 82 4.0E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 D521_1561 03fce11f31d45359582741bf829e3347 275 PRINTS PR00169 Potassium channel signature 85 105 4.0E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 D521_1561 03fce11f31d45359582741bf829e3347 275 PRINTS PR00169 Potassium channel signature 179 201 4.0E-36 T 14-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 D521_1561 03fce11f31d45359582741bf829e3347 275 Pfam PF00520 Ion transport protein 26 238 1.1E-32 T 14-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 D521_2046 6f1e703c8ac16ab2fb95be88dda00959 171 SUPERFAMILY SSF56925 12 170 5.57E-53 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel D521_2046 6f1e703c8ac16ab2fb95be88dda00959 171 ProDom PD103779 CRCA ANTIMICROBIAL RESISTANCE LIPOPROTEIN RCP A PEPTIDE ACYLATION LIPID EXPORTED 22 156 3.0E-32 T 14-10-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP D521_2046 6f1e703c8ac16ab2fb95be88dda00959 171 Gene3D G3DSA:2.40.160.20 9 170 2.8E-60 T 14-10-2018 D521_2046 6f1e703c8ac16ab2fb95be88dda00959 171 Pfam PF07017 Antimicrobial peptide resistance and lipid A acylation protein PagP 22 167 1.7E-52 T 14-10-2018 IPR009746 Antimicrobial peptide resistance/lipid A acylation PagP D521_0911 25890cb1699131756472e4bbc3c6b50f 240 Gene3D G3DSA:3.30.420.40 4 228 1.7E-53 T 14-10-2018 D521_0911 25890cb1699131756472e4bbc3c6b50f 240 SUPERFAMILY SSF53067 117 223 1.11E-9 T 14-10-2018 D521_0911 25890cb1699131756472e4bbc3c6b50f 240 Gene3D G3DSA:3.30.420.40 96 194 1.7E-53 T 14-10-2018 D521_0911 25890cb1699131756472e4bbc3c6b50f 240 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 225 1.1E-45 T 14-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 D521_0911 25890cb1699131756472e4bbc3c6b50f 240 Pfam PF00814 Glycoprotease family 37 147 6.3E-24 T 14-10-2018 IPR000905 Gcp-like domain D521_0911 25890cb1699131756472e4bbc3c6b50f 240 SUPERFAMILY SSF53067 3 105 1.55E-23 T 14-10-2018 D521_1621 36c4524a33d32e0835276638d5af7228 377 SUPERFAMILY SSF56235 26 350 4.24E-70 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_1621 36c4524a33d32e0835276638d5af7228 377 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 26 350 3.5E-52 T 14-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal D521_1621 36c4524a33d32e0835276638d5af7228 377 Gene3D G3DSA:3.60.60.10 26 369 1.8E-85 T 14-10-2018 D521_0606 6fa756ece64f5b97186f624bbd14e1fa 304 SUPERFAMILY SSF52151 45 303 1.19E-53 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase D521_0606 6fa756ece64f5b97186f624bbd14e1fa 304 Gene3D G3DSA:3.40.1090.10 41 153 6.5E-25 T 14-10-2018 D521_0606 6fa756ece64f5b97186f624bbd14e1fa 304 Pfam PF01734 Patatin-like phospholipase 52 213 4.1E-25 T 14-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 D521_1661 9cdc8ca785017034e1da7ff8b10dc424 470 Pfam PF07731 Multicopper oxidase 222 335 5.9E-21 T 14-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 D521_1661 9cdc8ca785017034e1da7ff8b10dc424 470 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 22 0.0011 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal D521_1661 9cdc8ca785017034e1da7ff8b10dc424 470 Gene3D G3DSA:2.60.40.420 197 333 5.6E-74 T 14-10-2018 IPR008972 Cupredoxin D521_1661 9cdc8ca785017034e1da7ff8b10dc424 470 Pfam PF07732 Multicopper oxidase 88 195 6.0E-36 T 14-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 D521_1661 9cdc8ca785017034e1da7ff8b10dc424 470 SUPERFAMILY SSF49503 40 194 1.46E-38 T 14-10-2018 IPR008972 Cupredoxin D521_1661 9cdc8ca785017034e1da7ff8b10dc424 470 ProSitePatterns PS00080 Multicopper oxidases signature 2. 320 331 - T 14-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 D521_1661 9cdc8ca785017034e1da7ff8b10dc424 470 SUPERFAMILY SSF49503 178 332 1.36E-28 T 14-10-2018 IPR008972 Cupredoxin D521_1661 9cdc8ca785017034e1da7ff8b10dc424 470 Gene3D G3DSA:2.60.40.420 74 196 5.6E-74 T 14-10-2018 IPR008972 Cupredoxin D521_1259 9c9209811ba6316cc501a5fc0fbc2648 236 Hamap MF_01220_B Uridylate kinase [pyrH]. 2 235 44.211 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 D521_1259 9c9209811ba6316cc501a5fc0fbc2648 236 Gene3D G3DSA:3.40.1160.10 1 236 3.8E-76 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily D521_1259 9c9209811ba6316cc501a5fc0fbc2648 236 SUPERFAMILY SSF53633 2 235 5.24E-71 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily D521_1259 9c9209811ba6316cc501a5fc0fbc2648 236 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 4 235 8.1E-101 T 14-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 D521_1259 9c9209811ba6316cc501a5fc0fbc2648 236 PIRSF PIRSF005650 1 236 1.4E-91 T 14-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 D521_1259 9c9209811ba6316cc501a5fc0fbc2648 236 Pfam PF00696 Amino acid kinase family 5 214 8.6E-28 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 D521_1607 1d91e1fe9c8452e33b181f3f118847d6 260 Gene3D G3DSA:3.90.226.10 14 202 4.7E-42 T 14-10-2018 D521_1607 1d91e1fe9c8452e33b181f3f118847d6 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 259 2.5E-33 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 D521_1607 1d91e1fe9c8452e33b181f3f118847d6 260 Gene3D G3DSA:1.10.12.10 205 257 2.9E-10 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal D521_1607 1d91e1fe9c8452e33b181f3f118847d6 260 SUPERFAMILY SSF52096 16 259 2.75E-54 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_1607 1d91e1fe9c8452e33b181f3f118847d6 260 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 102 122 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 D521_1039 e99d8495ab6556c89c8506255083da38 286 SUPERFAMILY SSF51735 122 279 6.13E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1039 e99d8495ab6556c89c8506255083da38 286 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 75 100 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 Gene3D G3DSA:3.40.50.10860 8 275 7.2E-112 T 14-10-2018 D521_1039 e99d8495ab6556c89c8506255083da38 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 2.8E-82 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 2.8E-82 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 2.8E-82 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 2.8E-82 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 2.8E-82 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 2.8E-82 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 2.8E-82 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 Gene3D G3DSA:3.40.50.720 6 258 7.2E-112 T 14-10-2018 D521_1039 e99d8495ab6556c89c8506255083da38 286 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 38.03 T 14-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 SUPERFAMILY SSF53223 1 121 5.85E-38 T 14-10-2018 D521_1039 e99d8495ab6556c89c8506255083da38 286 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 281 3.6E-70 T 14-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 2.8E-38 T 14-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_1039 e99d8495ab6556c89c8506255083da38 286 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 14-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 D521_0397 b6c40ccc69c0719f11ca754d3e2e1743 969 SUPERFAMILY SSF56176 12 268 2.62E-47 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 D521_0397 b6c40ccc69c0719f11ca754d3e2e1743 969 SUPERFAMILY SSF55103 271 532 1.03E-47 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 D521_0397 b6c40ccc69c0719f11ca754d3e2e1743 969 Pfam PF02754 Cysteine-rich domain 739 814 0.049 T 14-10-2018 IPR004017 Cysteine-rich domain D521_0397 b6c40ccc69c0719f11ca754d3e2e1743 969 Gene3D G3DSA:3.30.465.40 13 193 4.8E-36 T 14-10-2018 D521_0397 b6c40ccc69c0719f11ca754d3e2e1743 969 Gene3D G3DSA:3.30.70.2740 402 480 3.7E-6 T 14-10-2018 D521_0397 b6c40ccc69c0719f11ca754d3e2e1743 969 Pfam PF02913 FAD linked oxidases, C-terminal domain 268 520 4.2E-40 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 D521_0397 b6c40ccc69c0719f11ca754d3e2e1743 969 SUPERFAMILY SSF46548 560 641 5.13E-9 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_0397 b6c40ccc69c0719f11ca754d3e2e1743 969 Pfam PF13183 4Fe-4S dicluster domain 559 636 1.2E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_0397 b6c40ccc69c0719f11ca754d3e2e1743 969 Pfam PF01565 FAD binding domain 43 180 7.2E-32 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 D521_1028 8cdee5de7ea628b79e3d7d6dabac01f5 248 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 10 243 38.999 T 14-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 D521_1028 8cdee5de7ea628b79e3d7d6dabac01f5 248 PIRSF PIRSF037208 3 247 3.4E-87 T 14-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 D521_1028 8cdee5de7ea628b79e3d7d6dabac01f5 248 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 110 237 2.1E-37 T 14-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 D521_1028 8cdee5de7ea628b79e3d7d6dabac01f5 248 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 20 90 6.7E-19 T 14-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 D521_1028 8cdee5de7ea628b79e3d7d6dabac01f5 248 SUPERFAMILY SSF55729 85 246 1.35E-15 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_1077 e2243de79a429d251f7d4df9a3e4214e 397 Pfam PF04055 Radical SAM superfamily 94 278 2.2E-15 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 D521_1077 e2243de79a429d251f7d4df9a3e4214e 397 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 1 350 69.849 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 D521_1077 e2243de79a429d251f7d4df9a3e4214e 397 Gene3D G3DSA:1.10.150.530 1 50 8.8E-17 T 14-10-2018 D521_1077 e2243de79a429d251f7d4df9a3e4214e 397 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 3 353 1.4E-122 T 14-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 D521_1077 e2243de79a429d251f7d4df9a3e4214e 397 PIRSF PIRSF006004 1 363 3.2E-142 T 14-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 D521_1077 e2243de79a429d251f7d4df9a3e4214e 397 SUPERFAMILY SSF102114 90 304 1.22E-10 T 14-10-2018 D521_1077 e2243de79a429d251f7d4df9a3e4214e 397 Gene3D G3DSA:3.20.20.70 54 335 3.5E-105 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Gene3D G3DSA:2.120.10.90 527 855 3.8E-119 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 1 854 0.0 T 14-10-2018 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 855 23.557 T 14-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Gene3D G3DSA:3.90.199.10 17 505 5.0E-224 T 14-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 16 497 1.1E-156 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 SUPERFAMILY SSF101904 529 869 1.44E-107 T 14-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Gene3D G3DSA:3.30.1360.40 220 317 5.0E-224 T 14-10-2018 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Gene3D G3DSA:1.10.268.10 354 484 5.0E-224 T 14-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 689 734 9.2E-15 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 757 804 1.7E-12 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 807 850 6.2E-11 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 584 628 4.9E-8 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 641 684 1.1E-9 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 534 581 6.2E-10 T 14-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 SMART SM00434 1 490 1.6E-281 T 14-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_1484 e821d76274f6db3418217ecd6b62c6e1 891 SUPERFAMILY SSF56719 14 505 1.16E-177 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 D521_1724 810f2d7342ca77c1f5d7828919cbd7dc 316 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 311 7.6E-93 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 D521_1724 810f2d7342ca77c1f5d7828919cbd7dc 316 Pfam PF01687 Riboflavin kinase 183 310 1.7E-33 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 D521_1724 810f2d7342ca77c1f5d7828919cbd7dc 316 Gene3D G3DSA:3.40.50.620 6 185 1.8E-61 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1724 810f2d7342ca77c1f5d7828919cbd7dc 316 PIRSF PIRSF004491 4 315 4.3E-100 T 14-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 D521_1724 810f2d7342ca77c1f5d7828919cbd7dc 316 SUPERFAMILY SSF82114 173 313 3.49E-41 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 D521_1724 810f2d7342ca77c1f5d7828919cbd7dc 316 Gene3D G3DSA:2.40.30.30 187 316 5.9E-35 T 14-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 D521_1724 810f2d7342ca77c1f5d7828919cbd7dc 316 SMART SM00904 182 311 1.7E-53 T 14-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 D521_1724 810f2d7342ca77c1f5d7828919cbd7dc 316 SUPERFAMILY SSF52374 15 176 7.11E-36 T 14-10-2018 D521_1724 810f2d7342ca77c1f5d7828919cbd7dc 316 Pfam PF06574 FAD synthetase 15 165 3.7E-54 T 14-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 D521_1205 84c1eebe64070062ecdde901fc2b8c92 288 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 275 37.744 T 14-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 D521_1205 84c1eebe64070062ecdde901fc2b8c92 288 Gene3D G3DSA:3.40.50.150 1 287 3.6E-100 T 14-10-2018 D521_1205 84c1eebe64070062ecdde901fc2b8c92 288 SUPERFAMILY SSF53335 9 284 1.17E-79 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1205 84c1eebe64070062ecdde901fc2b8c92 288 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 35 278 1.8E-68 T 14-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 D521_0790 585c5af0d9163e8f2b7927d33d970965 263 SUPERFAMILY SSF52540 16 248 3.22E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0790 585c5af0d9163e8f2b7927d33d970965 263 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 17 263 2.2E-120 T 14-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 D521_0790 585c5af0d9163e8f2b7927d33d970965 263 Pfam PF00005 ABC transporter 32 188 3.8E-37 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0790 585c5af0d9163e8f2b7927d33d970965 263 Gene3D G3DSA:3.40.50.300 14 261 5.5E-69 T 14-10-2018 D521_0790 585c5af0d9163e8f2b7927d33d970965 263 SMART SM00382 41 251 1.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0790 585c5af0d9163e8f2b7927d33d970965 263 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0183 54fbde788dae266019f89a0684d6d181 208 Pfam PF07072 Cell division protein 2 182 3.1E-57 T 14-10-2018 IPR009777 Cell division protein ZapD D521_0183 54fbde788dae266019f89a0684d6d181 208 Gene3D G3DSA:2.60.440.10 136 206 1.4E-60 T 14-10-2018 IPR027462 Z ring-associated protein D, C-terminal D521_0183 54fbde788dae266019f89a0684d6d181 208 SUPERFAMILY SSF160950 2 206 7.85E-55 T 14-10-2018 IPR036268 ZapD domain superfamily D521_0183 54fbde788dae266019f89a0684d6d181 208 Gene3D G3DSA:1.10.3900.10 2 135 1.4E-60 T 14-10-2018 D521_0717 f32538271ea2ed9ea4ff476577dcb984 243 ProSitePatterns PS01277 Ribonuclease PH signature. 122 134 - T 14-10-2018 IPR018336 Ribonuclease PH, conserved site D521_0717 f32538271ea2ed9ea4ff476577dcb984 243 SUPERFAMILY SSF55666 159 242 1.44E-24 T 14-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0717 f32538271ea2ed9ea4ff476577dcb984 243 SUPERFAMILY SSF54211 7 187 1.11E-44 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0717 f32538271ea2ed9ea4ff476577dcb984 243 Hamap MF_00564 Ribonuclease PH [rph]. 17 243 44.56 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 D521_0717 f32538271ea2ed9ea4ff476577dcb984 243 Gene3D G3DSA:3.30.230.70 15 243 6.2E-59 T 14-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0717 f32538271ea2ed9ea4ff476577dcb984 243 Pfam PF03725 3' exoribonuclease family, domain 2 164 229 1.2E-9 T 14-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0717 f32538271ea2ed9ea4ff476577dcb984 243 Pfam PF01138 3' exoribonuclease family, domain 1 16 146 3.3E-20 T 14-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 D521_0717 f32538271ea2ed9ea4ff476577dcb984 243 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 8 242 1.6E-118 T 14-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 D521_0735 e4442bbdf2ed80d3d863f7d1e296603e 338 Gene3D G3DSA:3.40.50.720 1 181 5.0E-77 T 14-10-2018 D521_0735 e4442bbdf2ed80d3d863f7d1e296603e 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 2.7E-74 T 14-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 D521_0735 e4442bbdf2ed80d3d863f7d1e296603e 338 PIRSF PIRSF000116 2 203 1.2E-49 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 D521_0735 e4442bbdf2ed80d3d863f7d1e296603e 338 PIRSF PIRSF000116 201 332 1.0E-14 T 14-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 D521_0735 e4442bbdf2ed80d3d863f7d1e296603e 338 SUPERFAMILY SSF48179 183 333 1.38E-70 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_0735 e4442bbdf2ed80d3d863f7d1e296603e 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 1.7E-64 T 14-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 D521_0735 e4442bbdf2ed80d3d863f7d1e296603e 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 45.305 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 D521_0735 e4442bbdf2ed80d3d863f7d1e296603e 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 1.2E-133 T 14-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 D521_0735 e4442bbdf2ed80d3d863f7d1e296603e 338 Gene3D G3DSA:1.10.3730.40 182 338 2.1E-74 T 14-10-2018 D521_0735 e4442bbdf2ed80d3d863f7d1e296603e 338 SUPERFAMILY SSF51735 1 182 1.54E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0231 561d5802ea85c7ab3fe1279430b00069 342 SMART SM00846 3 159 1.6E-87 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 332 6.3E-125 T 14-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 157 164 - T 14-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 PIRSF PIRSF000149 1 342 3.6E-131 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 Gene3D G3DSA:3.30.360.10 158 323 1.1E-139 T 14-10-2018 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 Gene3D G3DSA:3.40.50.720 4 332 1.1E-139 T 14-10-2018 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 236 253 1.1E-36 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 116 129 1.1E-36 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 180 196 1.1E-36 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 153 171 1.1E-36 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 276 291 1.1E-36 T 14-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 SUPERFAMILY SSF51735 1 178 2.64E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0231 561d5802ea85c7ab3fe1279430b00069 342 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 110 1.7E-35 T 14-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 SUPERFAMILY SSF55347 159 322 6.55E-67 T 14-10-2018 D521_0231 561d5802ea85c7ab3fe1279430b00069 342 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 164 321 8.6E-60 T 14-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1696 5179a69221522e113a8e6bfeeb25becc 368 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 162 364 3.2E-34 T 14-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 D521_1696 5179a69221522e113a8e6bfeeb25becc 368 Gene3D G3DSA:3.90.380.10 16 359 1.7E-42 T 14-10-2018 D521_1696 5179a69221522e113a8e6bfeeb25becc 368 SUPERFAMILY SSF50022 4 140 1.57E-32 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 D521_1696 5179a69221522e113a8e6bfeeb25becc 368 Pfam PF00355 Rieske [2Fe-2S] domain 56 119 2.6E-10 T 14-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 D521_1696 5179a69221522e113a8e6bfeeb25becc 368 SUPERFAMILY SSF55961 157 366 1.1E-45 T 14-10-2018 D521_1696 5179a69221522e113a8e6bfeeb25becc 368 Gene3D G3DSA:2.102.10.10 37 150 1.7E-42 T 14-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 D521_1696 5179a69221522e113a8e6bfeeb25becc 368 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 94 114 2.5E-5 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 D521_1696 5179a69221522e113a8e6bfeeb25becc 368 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 24 49 2.5E-5 T 14-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 SUPERFAMILY SSF81653 200 298 8.63E-24 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 Pfam PF00403 Heavy-metal-associated domain 9 58 2.1E-5 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 170 683 7.3E-80 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 147 704 3.0E-141 T 14-10-2018 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 Pfam PF00702 haloacid dehalogenase-like hydrolase 395 612 4.5E-35 T 14-10-2018 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 SUPERFAMILY SSF55008 6 70 5.63E-11 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 Gene3D G3DSA:2.70.150.20 191 302 8.7E-34 T 14-10-2018 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 Gene3D G3DSA:3.40.1110.10 410 529 1.3E-83 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 SUPERFAMILY SSF56784 397 699 7.07E-53 T 14-10-2018 IPR036412 HAD-like superfamily D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 401 407 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 Gene3D G3DSA:3.40.50.1000 380 652 1.3E-83 T 14-10-2018 IPR023214 HAD superfamily D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 248 262 6.3E-24 T 14-10-2018 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 599 618 6.3E-24 T 14-10-2018 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 522 533 6.3E-24 T 14-10-2018 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 399 413 6.3E-24 T 14-10-2018 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 544 554 6.3E-24 T 14-10-2018 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 623 635 6.3E-24 T 14-10-2018 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 Gene3D G3DSA:3.30.70.100 2 78 1.4E-6 T 14-10-2018 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 SUPERFAMILY SSF81665 148 391 1.11E-14 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 147 702 5.7E-171 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00941 Cadmium-transporting ATPase signature 283 297 7.3E-14 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00941 Cadmium-transporting ATPase signature 182 202 7.3E-14 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00941 Cadmium-transporting ATPase signature 128 140 7.3E-14 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00941 Cadmium-transporting ATPase signature 264 280 7.3E-14 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 PRINTS PR00941 Cadmium-transporting ATPase signature 9 18 7.3E-14 T 14-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 D521_1669 b3302a6613887fda39aec5fc8bf4223e 705 Pfam PF00122 E1-E2 ATPase 198 379 1.6E-52 T 14-10-2018 D521_0964 8d2a53017f40ff830444569401a958b0 264 SUPERFAMILY SSF109998 27 157 3.26E-19 T 14-10-2018 IPR027304 Trigger factor/SurA domain superfamily D521_0964 8d2a53017f40ff830444569401a958b0 264 SUPERFAMILY SSF54534 130 223 9.16E-31 T 14-10-2018 D521_0964 8d2a53017f40ff830444569401a958b0 264 Gene3D G3DSA:1.10.4030.10 23 124 5.6E-7 T 14-10-2018 D521_0964 8d2a53017f40ff830444569401a958b0 264 Pfam PF00639 PPIC-type PPIASE domain 140 219 2.4E-24 T 14-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 D521_0964 8d2a53017f40ff830444569401a958b0 264 Pfam PF13624 SurA N-terminal domain 24 119 2.1E-6 T 14-10-2018 D521_0964 8d2a53017f40ff830444569401a958b0 264 Gene3D G3DSA:3.10.50.40 125 245 7.7E-35 T 14-10-2018 D521_0828 fefd2fb718b1ff6a1bd82be187a3b459 371 SUPERFAMILY SSF103263 4 352 4.06E-142 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 D521_0828 fefd2fb718b1ff6a1bd82be187a3b459 371 ProSitePatterns PS00788 Chorismate synthase signature 2. 124 140 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 D521_0828 fefd2fb718b1ff6a1bd82be187a3b459 371 PIRSF PIRSF001456 3 359 2.9E-133 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 D521_0828 fefd2fb718b1ff6a1bd82be187a3b459 371 Hamap MF_00300 Chorismate synthase [aroC]. 10 354 35.604 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 D521_0828 fefd2fb718b1ff6a1bd82be187a3b459 371 TIGRFAM TIGR00033 aroC: chorismate synthase 10 350 7.2E-136 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 D521_0828 fefd2fb718b1ff6a1bd82be187a3b459 371 Gene3D G3DSA:3.60.150.10 1 362 2.0E-146 T 14-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 D521_0828 fefd2fb718b1ff6a1bd82be187a3b459 371 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 D521_0828 fefd2fb718b1ff6a1bd82be187a3b459 371 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 14-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 D521_0828 fefd2fb718b1ff6a1bd82be187a3b459 371 Pfam PF01264 Chorismate synthase 10 345 1.2E-132 T 14-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 D521_0595 ef90d53d3fc124be9a6f4e6ed4f1d5ca 281 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 14 221 4.0E-40 T 14-10-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 D521_0595 ef90d53d3fc124be9a6f4e6ed4f1d5ca 281 PIRSF PIRSF015582 11 281 4.9E-72 T 14-10-2018 IPR011206 Citrate lyase beta subunit-like D521_0595 ef90d53d3fc124be9a6f4e6ed4f1d5ca 281 Gene3D G3DSA:3.20.20.60 10 280 2.0E-77 T 14-10-2018 D521_0595 ef90d53d3fc124be9a6f4e6ed4f1d5ca 281 SUPERFAMILY SSF51621 13 233 4.54E-57 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 D521_1558 5313d88861ab661caf13adda7f1a6a79 59 Pfam PF10013 Uncharacterized protein conserved in bacteria (DUF2256) 12 50 3.8E-21 T 14-10-2018 IPR017136 Uncharacterised conserved protein UCP037205 D521_1558 5313d88861ab661caf13adda7f1a6a79 59 PIRSF PIRSF037205 9 59 4.3E-21 T 14-10-2018 IPR017136 Uncharacterised conserved protein UCP037205 D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 Gene3D G3DSA:1.25.40.80 129 292 1.1E-50 T 14-10-2018 D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 SUPERFAMILY SSF48173 195 415 9.03E-63 T 14-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 Gene3D G3DSA:3.40.50.620 1 128 6.4E-34 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 Pfam PF03441 FAD binding domain of DNA photolyase 272 415 2.1E-37 T 14-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 Pfam PF00875 DNA photolyase 5 169 5.8E-34 T 14-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 SUPERFAMILY SSF52425 4 173 1.7E-40 T 14-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 TIGRFAM TIGR02765 crypto_DASH: cryptochrome, DASH family 4 415 2.4E-141 T 14-10-2018 IPR014133 Cryptochrome DASH GO:0003913|GO:0006281 D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 PRINTS PR00147 DNA photolyase signature 318 334 4.8E-10 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 PRINTS PR00147 DNA photolyase signature 338 356 4.8E-10 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 PRINTS PR00147 DNA photolyase signature 377 391 4.8E-10 T 14-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 D521_1557 f5cbe4bea0020c8c05419f97a7fcf136 418 Gene3D G3DSA:1.10.579.10 302 417 6.1E-45 T 14-10-2018 D521_0891 ef8996f863c8cad7d3c9ca265c68b477 645 Gene3D G3DSA:3.20.20.540 219 531 3.7E-151 T 14-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 D521_0891 ef8996f863c8cad7d3c9ca265c68b477 645 Pfam PF01964 Radical SAM ThiC family 145 596 5.3E-196 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 D521_0891 ef8996f863c8cad7d3c9ca265c68b477 645 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 143 600 97.289 T 14-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 D521_0891 ef8996f863c8cad7d3c9ca265c68b477 645 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 143 599 4.6E-212 T 14-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 D521_0891 ef8996f863c8cad7d3c9ca265c68b477 645 Pfam PF13667 ThiC-associated domain 28 103 4.3E-28 T 14-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 D521_1527 70db2c3202c56a56e36b1e9b59d027a5 216 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 10 188 5.1E-79 T 14-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO D521_1527 70db2c3202c56a56e36b1e9b59d027a5 216 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 12 188 2.9E-82 T 14-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO D521_1527 70db2c3202c56a56e36b1e9b59d027a5 216 SUPERFAMILY SSF46626 21 201 5.23E-29 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1527 70db2c3202c56a56e36b1e9b59d027a5 216 Gene3D G3DSA:1.10.760.10 47 207 8.0E-69 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1670 21e39d9738a28f32c9554081ee3a431b 132 Pfam PF13411 MerR HTH family regulatory protein 1 68 2.5E-20 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 D521_1670 21e39d9738a28f32c9554081ee3a431b 132 TIGRFAM TIGR02047 CadR-PbrR: Cd(II)/Pb(II)-responsive transcriptional regulator 1 127 5.2E-52 T 14-10-2018 IPR011791 Cd(II)/Pb(II)-responsive transcriptional regulator GO:0003677|GO:0003700|GO:0045893|GO:0046872 D521_1670 21e39d9738a28f32c9554081ee3a431b 132 Gene3D G3DSA:1.10.1660.10 1 126 2.7E-33 T 14-10-2018 D521_1670 21e39d9738a28f32c9554081ee3a431b 132 SMART SM00422 1 70 1.1E-29 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 D521_1670 21e39d9738a28f32c9554081ee3a431b 132 SUPERFAMILY SSF46955 1 127 2.89E-34 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily D521_1670 21e39d9738a28f32c9554081ee3a431b 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 3.4E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 D521_1670 21e39d9738a28f32c9554081ee3a431b 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 3.4E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 D521_1670 21e39d9738a28f32c9554081ee3a431b 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 3.4E-10 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 D521_0257 424f9797137e3600510cb048b16df05d 536 Pfam PF02321 Outer membrane efflux protein 93 283 3.5E-24 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_0257 424f9797137e3600510cb048b16df05d 536 Pfam PF02321 Outer membrane efflux protein 331 517 8.9E-23 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_0257 424f9797137e3600510cb048b16df05d 536 SUPERFAMILY SSF56954 91 534 9.02E-70 T 14-10-2018 D521_0257 424f9797137e3600510cb048b16df05d 536 Gene3D G3DSA:1.20.1600.10 89 536 7.7E-86 T 14-10-2018 D521_0202 a71b0c42f84be15379714d438e2604e6 555 Pfam PF04073 Aminoacyl-tRNA editing domain 232 356 4.9E-28 T 14-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 D521_0202 a71b0c42f84be15379714d438e2604e6 555 SUPERFAMILY SSF52954 441 548 2.45E-30 T 14-10-2018 D521_0202 a71b0c42f84be15379714d438e2604e6 555 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 543 5.9E-220 T 14-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 D521_0202 a71b0c42f84be15379714d438e2604e6 555 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 70 435 1.4E-48 T 14-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0202 a71b0c42f84be15379714d438e2604e6 555 Gene3D G3DSA:3.30.930.10 1 442 7.7E-229 T 14-10-2018 D521_0202 a71b0c42f84be15379714d438e2604e6 555 PIRSF PIRSF001535 1 551 2.4E-254 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 D521_0202 a71b0c42f84be15379714d438e2604e6 555 Gene3D G3DSA:3.40.50.800 443 531 7.7E-229 T 14-10-2018 IPR036621 Anticodon-binding domain superfamily D521_0202 a71b0c42f84be15379714d438e2604e6 555 SUPERFAMILY SSF55826 193 366 3.27E-34 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 D521_0202 a71b0c42f84be15379714d438e2604e6 555 Gene3D G3DSA:3.90.960.10 215 366 7.7E-229 T 14-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 D521_0202 a71b0c42f84be15379714d438e2604e6 555 Pfam PF03129 Anticodon binding domain 453 544 1.7E-18 T 14-10-2018 IPR004154 Anticodon-binding D521_0202 a71b0c42f84be15379714d438e2604e6 555 SUPERFAMILY SSF55681 1 455 2.49E-99 T 14-10-2018 D521_0202 a71b0c42f84be15379714d438e2604e6 555 PRINTS PR01046 Prolyl-tRNA synthetase signature 43 61 4.6E-19 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 D521_0202 a71b0c42f84be15379714d438e2604e6 555 PRINTS PR01046 Prolyl-tRNA synthetase signature 119 130 4.6E-19 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 D521_0202 a71b0c42f84be15379714d438e2604e6 555 PRINTS PR01046 Prolyl-tRNA synthetase signature 109 117 4.6E-19 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 D521_0202 a71b0c42f84be15379714d438e2604e6 555 PRINTS PR01046 Prolyl-tRNA synthetase signature 79 90 4.6E-19 T 14-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 D521_0202 a71b0c42f84be15379714d438e2604e6 555 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 548 37.629 T 14-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 D521_0248 7d5722d9ce1ae1f931a8ca55efec8228 168 SUPERFAMILY SSF53271 17 149 7.4E-27 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like D521_0248 7d5722d9ce1ae1f931a8ca55efec8228 168 Pfam PF00156 Phosphoribosyl transferase domain 26 138 4.9E-14 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 D521_0248 7d5722d9ce1ae1f931a8ca55efec8228 168 Gene3D G3DSA:3.40.50.2020 5 166 3.1E-31 T 14-10-2018 D521_0195 e4e38ab4a56da5347ac3ff25c2362bc2 334 Pfam PF00348 Polyprenyl synthetase 38 284 4.6E-77 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 D521_0195 e4e38ab4a56da5347ac3ff25c2362bc2 334 Gene3D G3DSA:1.10.600.10 1 334 5.5E-110 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily D521_0195 e4e38ab4a56da5347ac3ff25c2362bc2 334 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 90 104 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site D521_0195 e4e38ab4a56da5347ac3ff25c2362bc2 334 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 212 224 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site D521_0195 e4e38ab4a56da5347ac3ff25c2362bc2 334 SUPERFAMILY SSF48576 8 333 2.3E-95 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 Gene3D G3DSA:3.60.20.40 350 529 5.2E-63 T 14-10-2018 D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 SUPERFAMILY SSF56235 14 529 3.67E-168 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 Pfam PF01019 Gamma-glutamyltranspeptidase 33 524 1.1E-148 T 14-10-2018 D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 Gene3D G3DSA:1.10.246.130 239 349 1.8E-26 T 14-10-2018 D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 125 144 1.0E-34 T 14-10-2018 D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 400 415 1.0E-34 T 14-10-2018 D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 252 271 1.0E-34 T 14-10-2018 D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 424 441 1.0E-34 T 14-10-2018 D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 107 125 1.0E-34 T 14-10-2018 D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 40 65 1.0E-34 T 14-10-2018 D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 223 239 1.0E-34 T 14-10-2018 D521_0668 a60293f05b22a6d2081be6fa4ff3bd8d 529 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 346 364 1.0E-34 T 14-10-2018 D521_1133 b19eb7af1641b945ae680bc16aaf3e79 116 SUPERFAMILY SSF54637 1 114 1.51E-24 T 14-10-2018 IPR029069 HotDog domain superfamily D521_1133 b19eb7af1641b945ae680bc16aaf3e79 116 Pfam PF03061 Thioesterase superfamily 1 77 3.7E-13 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 D521_1133 b19eb7af1641b945ae680bc16aaf3e79 116 PIRSF PIRSF003230 1 115 1.5E-22 T 14-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 D521_1133 b19eb7af1641b945ae680bc16aaf3e79 116 Gene3D G3DSA:3.10.129.10 1 116 6.1E-24 T 14-10-2018 D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 SUPERFAMILY SSF55781 16 211 4.36E-26 T 14-10-2018 D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 Pfam PF13487 HD domain 394 459 7.7E-22 T 14-10-2018 D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 SUPERFAMILY SSF109604 393 506 6.91E-10 T 14-10-2018 D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 Gene3D G3DSA:1.10.3210.10 209 330 3.8E-20 T 14-10-2018 D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 Gene3D G3DSA:1.10.3210.10 382 519 3.0E-27 T 14-10-2018 D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 Pfam PF01966 HD domain 232 313 2.5E-7 T 14-10-2018 IPR006674 HD domain D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 Pfam PF01590 GAF domain 36 199 5.6E-15 T 14-10-2018 IPR003018 GAF domain GO:0005515 D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 SMART SM00065 34 209 1.5E-15 T 14-10-2018 IPR003018 GAF domain GO:0005515 D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 Gene3D G3DSA:3.30.450.40 10 208 1.9E-40 T 14-10-2018 IPR029016 GAF-like domain superfamily D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 SUPERFAMILY SSF109604 204 345 1.14E-9 T 14-10-2018 D521_0651 d80c1ea50c05f2b4dfd80608f99e2feb 541 SMART SM00471 226 477 7.4E-6 T 14-10-2018 IPR003607 HD/PDEase domain D521_2064 89c5e623fff4d7470218195dd068aa3b 414 SUPERFAMILY SSF55785 35 139 2.79E-13 T 14-10-2018 IPR035965 PAS domain superfamily D521_2064 89c5e623fff4d7470218195dd068aa3b 414 SUPERFAMILY SSF47384 310 344 2.75E-5 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 D521_2064 89c5e623fff4d7470218195dd068aa3b 414 Pfam PF08447 PAS fold 44 117 9.6E-8 T 14-10-2018 IPR013655 PAS fold-3 GO:0005515 D521_2064 89c5e623fff4d7470218195dd068aa3b 414 Gene3D G3DSA:1.10.287.130 287 381 1.5E-12 T 14-10-2018 D521_2064 89c5e623fff4d7470218195dd068aa3b 414 Gene3D G3DSA:3.30.450.20 135 267 3.2E-18 T 14-10-2018 D521_2064 89c5e623fff4d7470218195dd068aa3b 414 Pfam PF00512 His Kinase A (phospho-acceptor) domain 313 367 1.9E-6 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_2064 89c5e623fff4d7470218195dd068aa3b 414 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 36 144 6.1E-8 T 14-10-2018 IPR000014 PAS domain D521_2064 89c5e623fff4d7470218195dd068aa3b 414 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 138 263 2.0E-12 T 14-10-2018 IPR000014 PAS domain D521_2064 89c5e623fff4d7470218195dd068aa3b 414 SUPERFAMILY SSF55785 153 263 1.93E-15 T 14-10-2018 IPR035965 PAS domain superfamily D521_2064 89c5e623fff4d7470218195dd068aa3b 414 SMART SM00091 17 89 0.49 T 14-10-2018 IPR000014 PAS domain D521_2064 89c5e623fff4d7470218195dd068aa3b 414 SMART SM00091 142 209 1.6 T 14-10-2018 IPR000014 PAS domain D521_2064 89c5e623fff4d7470218195dd068aa3b 414 Pfam PF08448 PAS fold 151 258 5.5E-14 T 14-10-2018 IPR013656 PAS fold-4 D521_2064 89c5e623fff4d7470218195dd068aa3b 414 Gene3D G3DSA:3.30.450.20 15 134 5.3E-15 T 14-10-2018 D521_1341 c8375ae0e9bcae1b667e5c2695c32b8b 243 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 8 109 2.4E-29 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1341 c8375ae0e9bcae1b667e5c2695c32b8b 243 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 147 158 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1341 c8375ae0e9bcae1b667e5c2695c32b8b 243 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 D521_1341 c8375ae0e9bcae1b667e5c2695c32b8b 243 Gene3D G3DSA:1.10.1060.10 104 238 1.7E-29 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_1341 c8375ae0e9bcae1b667e5c2695c32b8b 243 SUPERFAMILY SSF46548 104 231 2.09E-22 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_1341 c8375ae0e9bcae1b667e5c2695c32b8b 243 Pfam PF13183 4Fe-4S dicluster domain 146 216 7.5E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1341 c8375ae0e9bcae1b667e5c2695c32b8b 243 Gene3D G3DSA:3.10.20.30 1 103 1.6E-27 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_1341 c8375ae0e9bcae1b667e5c2695c32b8b 243 SUPERFAMILY SSF54292 7 103 3.99E-23 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 D521_1341 c8375ae0e9bcae1b667e5c2695c32b8b 243 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 18 227 2.8E-56 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_0107 ebfb169ce7cd4770a3b28cf39151a158 357 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 8 353 1.4E-89 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 D521_0107 ebfb169ce7cd4770a3b28cf39151a158 357 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 210 219 - T 14-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 D521_0107 ebfb169ce7cd4770a3b28cf39151a158 357 Gene3D G3DSA:3.90.1150.10 20 343 1.4E-104 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_0107 ebfb169ce7cd4770a3b28cf39151a158 357 SUPERFAMILY SSF53383 5 354 5.15E-75 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0107 ebfb169ce7cd4770a3b28cf39151a158 357 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 354 54.539 T 14-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 D521_0107 ebfb169ce7cd4770a3b28cf39151a158 357 Gene3D G3DSA:3.40.640.10 38 262 1.4E-104 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0107 ebfb169ce7cd4770a3b28cf39151a158 357 Pfam PF00155 Aminotransferase class I and II 26 349 4.8E-54 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 Gene3D G3DSA:3.90.190.20 352 511 3.8E-54 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 22 507 2.3E-139 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 SUPERFAMILY SSF53623 104 346 5.23E-63 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 4 510 32.479 T 14-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 Pfam PF01225 Mur ligase family, catalytic domain 23 99 3.0E-4 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 SUPERFAMILY SSF53244 349 507 5.36E-46 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 Pfam PF02875 Mur ligase family, glutamate ligase domain 349 442 1.4E-22 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 Gene3D G3DSA:3.40.1190.10 104 351 3.6E-71 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 SUPERFAMILY SSF63418 21 102 1.44E-12 T 14-10-2018 IPR035911 MurE/MurF, N-terminal D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 Pfam PF08245 Mur ligase middle domain 113 328 7.8E-42 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 D521_0165 8ce1e4f2e1352e4d7f5122e860616b47 514 Gene3D G3DSA:3.40.1390.10 7 102 1.0E-13 T 14-10-2018 D521_0544 4a63a9e3a413edfb2a25e18dbb9f6b50 562 Pfam PF00920 Dehydratase family 36 555 4.0E-205 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 D521_0544 4a63a9e3a413edfb2a25e18dbb9f6b50 562 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 D521_0544 4a63a9e3a413edfb2a25e18dbb9f6b50 562 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 466 477 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 D521_0544 4a63a9e3a413edfb2a25e18dbb9f6b50 562 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 19 558 7.7E-231 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 D521_0544 4a63a9e3a413edfb2a25e18dbb9f6b50 562 SUPERFAMILY SSF52016 381 559 1.88E-57 T 14-10-2018 D521_0544 4a63a9e3a413edfb2a25e18dbb9f6b50 562 Gene3D G3DSA:3.50.30.80 380 530 2.1E-51 T 14-10-2018 D521_0544 4a63a9e3a413edfb2a25e18dbb9f6b50 562 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 6 558 44.29 T 14-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 D521_0544 4a63a9e3a413edfb2a25e18dbb9f6b50 562 SUPERFAMILY SSF143975 3 379 2.62E-134 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 D521_1083 0a1a7a161b78a4f3132894b21c16bb6e 218 Gene3D G3DSA:3.40.50.150 3 217 5.2E-64 T 14-10-2018 D521_1083 0a1a7a161b78a4f3132894b21c16bb6e 218 SUPERFAMILY SSF53335 25 216 1.27E-33 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1083 0a1a7a161b78a4f3132894b21c16bb6e 218 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 12 216 3.4E-56 T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 D521_1083 0a1a7a161b78a4f3132894b21c16bb6e 218 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 13 216 1.2E-51 T 14-10-2018 D521_1083 0a1a7a161b78a4f3132894b21c16bb6e 218 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 138 153 - T 14-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 SUPERFAMILY SSF56752 335 606 1.7E-41 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 SUPERFAMILY SSF56322 41 391 1.96E-97 T 14-10-2018 IPR005801 ADC synthase GO:0009058 D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 PRINTS PR00095 Anthranilate synthase component I signature 227 240 9.7E-11 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 PRINTS PR00095 Anthranilate synthase component I signature 241 254 9.7E-11 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 PRINTS PR00095 Anthranilate synthase component I signature 321 335 9.7E-11 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 PRINTS PR00095 Anthranilate synthase component I signature 336 350 9.7E-11 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 Gene3D G3DSA:3.60.120.10 26 395 2.0E-110 T 14-10-2018 IPR005801 ADC synthase GO:0009058 D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 Pfam PF01063 Amino-transferase class IV 397 606 2.8E-38 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 Pfam PF00425 chorismate binding enzyme 132 385 1.5E-82 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 Gene3D G3DSA:3.20.10.10 486 608 5.2E-30 T 14-10-2018 D521_1025 ff7ef912a308c3822c3b480d1171ccae 608 Gene3D G3DSA:3.30.470.10 396 475 1.5E-8 T 14-10-2018 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 Pfam PF00406 Adenylate kinase 5 185 2.0E-57 T 14-10-2018 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 SUPERFAMILY SSF52540 1 216 6.99E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 14-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 Pfam PF05191 Adenylate kinase, active site lid 123 158 3.7E-18 T 14-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 Hamap MF_00235 Adenylate kinase [adk]. 1 221 52.677 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 Gene3D G3DSA:3.40.50.300 1 220 1.9E-76 T 14-10-2018 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 PRINTS PR00094 Adenylate kinase signature 32 46 3.7E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 PRINTS PR00094 Adenylate kinase signature 156 171 3.7E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 PRINTS PR00094 Adenylate kinase signature 4 17 3.7E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 PRINTS PR00094 Adenylate kinase signature 173 187 3.7E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 PRINTS PR00094 Adenylate kinase signature 81 97 3.7E-35 T 14-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 D521_0285 5c3ecbcf64abaf5a255c271d7b88a170 221 TIGRFAM TIGR01351 adk: adenylate kinase 2 186 1.4E-73 T 14-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 D521_1464 bec48f472d943f5bf4935bc8023e814b 550 Pfam PF13193 AMP-binding enzyme C-terminal domain 458 532 2.1E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain D521_1464 bec48f472d943f5bf4935bc8023e814b 550 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 14-10-2018 IPR020845 AMP-binding, conserved site D521_1464 bec48f472d943f5bf4935bc8023e814b 550 Gene3D G3DSA:3.30.300.310 445 547 3.2E-33 T 14-10-2018 D521_1464 bec48f472d943f5bf4935bc8023e814b 550 SUPERFAMILY SSF56801 16 543 3.27E-137 T 14-10-2018 D521_1464 bec48f472d943f5bf4935bc8023e814b 550 Pfam PF00501 AMP-binding enzyme 25 449 2.8E-93 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 D521_1464 bec48f472d943f5bf4935bc8023e814b 550 Gene3D G3DSA:3.40.50.12780 10 444 2.5E-103 T 14-10-2018 D521_1966 f4ac6ff6d4ab38ee78f556be7d997a5e 273 SUPERFAMILY SSF53067 133 269 4.32E-25 T 14-10-2018 D521_1966 f4ac6ff6d4ab38ee78f556be7d997a5e 273 Gene3D G3DSA:3.30.420.490 134 261 9.0E-60 T 14-10-2018 D521_1966 f4ac6ff6d4ab38ee78f556be7d997a5e 273 Pfam PF03309 Type III pantothenate kinase 4 215 1.1E-50 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 D521_1966 f4ac6ff6d4ab38ee78f556be7d997a5e 273 Hamap MF_01274 Type III pantothenate kinase [coaX]. 3 273 18.049 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 D521_1966 f4ac6ff6d4ab38ee78f556be7d997a5e 273 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 5 244 5.9E-26 T 14-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 D521_1966 f4ac6ff6d4ab38ee78f556be7d997a5e 273 SUPERFAMILY SSF53067 4 129 6.47E-19 T 14-10-2018 D521_1966 f4ac6ff6d4ab38ee78f556be7d997a5e 273 Gene3D G3DSA:3.30.420.40 5 265 9.0E-60 T 14-10-2018 D521_0275 58bfb1fb36b1fa67701450b2e17ba98b 245 Pfam PF13525 Outer membrane lipoprotein 123 240 7.8E-17 T 14-10-2018 IPR039565 Outer membrane lipoprotein BamD-like D521_0275 58bfb1fb36b1fa67701450b2e17ba98b 245 Pfam PF16331 TolA binding protein trimerisation 55 111 2.6E-14 T 14-10-2018 IPR032519 YbgF, trimerisation domain GO:0070206 D521_0275 58bfb1fb36b1fa67701450b2e17ba98b 245 SUPERFAMILY SSF48452 26 231 2.37E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0275 58bfb1fb36b1fa67701450b2e17ba98b 245 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 14 244 18.187 T 14-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 D521_0275 58bfb1fb36b1fa67701450b2e17ba98b 245 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 123 239 1.8E-33 T 14-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal D521_0275 58bfb1fb36b1fa67701450b2e17ba98b 245 Gene3D G3DSA:1.25.40.10 124 245 4.2E-29 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1382 fcab8743248b1dd6d003e989a22672df 413 SUPERFAMILY SSF63867 337 409 1.44E-13 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1382 fcab8743248b1dd6d003e989a22672df 413 Pfam PF00994 Probable molybdopterin binding domain 185 326 1.1E-24 T 14-10-2018 IPR001453 MoaB/Mog domain D521_1382 fcab8743248b1dd6d003e989a22672df 413 Pfam PF03453 MoeA N-terminal region (domain I and II) 9 170 5.4E-43 T 14-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1382 fcab8743248b1dd6d003e989a22672df 413 Gene3D G3DSA:3.90.105.10 26 177 1.3E-125 T 14-10-2018 D521_1382 fcab8743248b1dd6d003e989a22672df 413 Gene3D G3DSA:2.170.190.11 50 144 1.3E-125 T 14-10-2018 D521_1382 fcab8743248b1dd6d003e989a22672df 413 SUPERFAMILY SSF63882 3 179 1.83E-50 T 14-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1382 fcab8743248b1dd6d003e989a22672df 413 Pfam PF03454 MoeA C-terminal region (domain IV) 343 408 3.0E-10 T 14-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1382 fcab8743248b1dd6d003e989a22672df 413 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 256 289 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 D521_1382 fcab8743248b1dd6d003e989a22672df 413 SMART SM00852 183 328 1.5E-42 T 14-10-2018 IPR001453 MoaB/Mog domain D521_1382 fcab8743248b1dd6d003e989a22672df 413 SUPERFAMILY SSF53218 180 332 9.03E-40 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily D521_1382 fcab8743248b1dd6d003e989a22672df 413 Gene3D G3DSA:3.40.980.10 178 337 1.3E-125 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily D521_1382 fcab8743248b1dd6d003e989a22672df 413 Gene3D G3DSA:2.40.340.10 338 403 1.3E-125 T 14-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1340 aaa09e97b59985b0052974bbd17d2c2e 116 Gene3D G3DSA:1.20.1300.10 4 115 7.5E-13 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1340 aaa09e97b59985b0052974bbd17d2c2e 116 SUPERFAMILY SSF81343 7 111 4.8E-15 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1340 aaa09e97b59985b0052974bbd17d2c2e 116 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 7 106 3.8E-7 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_0052 373a1d4febea0db624817e893b8ecaeb 218 ProSitePatterns PS00474 Ribosomal protein L3 signature. 105 128 - T 14-10-2018 IPR019926 Ribosomal protein L3, conserved site D521_0052 373a1d4febea0db624817e893b8ecaeb 218 Gene3D G3DSA:2.40.30.10 134 214 5.8E-15 T 14-10-2018 D521_0052 373a1d4febea0db624817e893b8ecaeb 218 Gene3D G3DSA:2.40.50.620 34 97 2.3E-12 T 14-10-2018 D521_0052 373a1d4febea0db624817e893b8ecaeb 218 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 207 1.2E-80 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0052 373a1d4febea0db624817e893b8ecaeb 218 SUPERFAMILY SSF50447 2 216 2.38E-73 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily D521_0052 373a1d4febea0db624817e893b8ecaeb 218 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 211 36.856 T 14-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0052 373a1d4febea0db624817e893b8ecaeb 218 Pfam PF00297 Ribosomal protein L3 52 187 2.6E-14 T 14-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1882 cdc07e06e4d063838e5b210c7eb3ed2d 141 Pfam PF02566 OsmC-like protein 35 133 6.1E-18 T 14-10-2018 IPR003718 OsmC/Ohr family D521_1882 cdc07e06e4d063838e5b210c7eb3ed2d 141 SUPERFAMILY SSF82784 1 135 1.83E-39 T 14-10-2018 IPR036102 OsmC/Ohr superfamily D521_1882 cdc07e06e4d063838e5b210c7eb3ed2d 141 Gene3D G3DSA:2.20.25.10 1 40 4.9E-6 T 14-10-2018 D521_1882 cdc07e06e4d063838e5b210c7eb3ed2d 141 Gene3D G3DSA:3.30.300.20 41 137 1.2E-30 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta D521_0124 6f3454f8a0a3255e5d3611dd6bc57c83 203 Pfam PF13417 Glutathione S-transferase, N-terminal domain 4 77 1.9E-17 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 D521_0124 6f3454f8a0a3255e5d3611dd6bc57c83 203 Gene3D G3DSA:1.20.1050.10 80 187 4.4E-75 T 14-10-2018 D521_0124 6f3454f8a0a3255e5d3611dd6bc57c83 203 Pfam PF00043 Glutathione S-transferase, C-terminal domain 114 188 4.0E-7 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal D521_0124 6f3454f8a0a3255e5d3611dd6bc57c83 203 SUPERFAMILY SSF47616 73 202 4.83E-23 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily D521_0124 6f3454f8a0a3255e5d3611dd6bc57c83 203 SUPERFAMILY SSF52833 1 101 1.27E-26 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0124 6f3454f8a0a3255e5d3611dd6bc57c83 203 Gene3D G3DSA:3.40.30.10 2 192 4.4E-75 T 14-10-2018 D521_1922 93a852c1e0685efd9596517fc92dba60 216 SUPERFAMILY SSF53335 27 207 5.58E-37 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1922 93a852c1e0685efd9596517fc92dba60 216 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 25 180 1.5E-41 T 14-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 D521_1922 93a852c1e0685efd9596517fc92dba60 216 Gene3D G3DSA:3.40.50.150 16 215 3.2E-44 T 14-10-2018 D521_1922 93a852c1e0685efd9596517fc92dba60 216 Pfam PF03602 Conserved hypothetical protein 95 27 165 1.6E-42 T 14-10-2018 D521_0415 45abddbf600d60882fa162f98ff9de7a 141 SMART SM00091 5 71 3.7E-10 T 14-10-2018 IPR000014 PAS domain D521_0415 45abddbf600d60882fa162f98ff9de7a 141 Pfam PF00989 PAS fold 7 116 6.2E-12 T 14-10-2018 IPR013767 PAS fold GO:0006355 D521_0415 45abddbf600d60882fa162f98ff9de7a 141 Gene3D G3DSA:3.30.450.20 5 136 1.3E-24 T 14-10-2018 D521_0415 45abddbf600d60882fa162f98ff9de7a 141 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 130 1.1E-17 T 14-10-2018 IPR000014 PAS domain D521_0415 45abddbf600d60882fa162f98ff9de7a 141 SUPERFAMILY SSF55785 16 132 1.93E-25 T 14-10-2018 IPR035965 PAS domain superfamily D521_0994 1d2143ffe044bc9ff0e736d1227e71b9 264 Gene3D G3DSA:3.30.70.1070 186 260 9.4E-13 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 D521_0994 1d2143ffe044bc9ff0e736d1227e71b9 264 Pfam PF05036 Sporulation related domain 185 256 9.5E-17 T 14-10-2018 IPR007730 Sporulation-like domain GO:0042834 D521_0994 1d2143ffe044bc9ff0e736d1227e71b9 264 SUPERFAMILY SSF110997 184 258 4.71E-14 T 14-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 D521_1843 fa6f93a9815c42f7dc60c9cf10ecc8cc 209 Pfam PF03458 UPF0126 domain 7 79 6.8E-18 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 D521_1843 fa6f93a9815c42f7dc60c9cf10ecc8cc 209 Pfam PF03458 UPF0126 domain 94 167 2.4E-16 T 14-10-2018 IPR005115 Uncharacterised domain UPF0126 D521_0293 9cdfc2d05e4a179fef0553b0f01ab7a5 346 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 223 345 5.2E-32 T 14-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0293 9cdfc2d05e4a179fef0553b0f01ab7a5 346 Gene3D G3DSA:3.90.78.10 236 346 9.7E-42 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0293 9cdfc2d05e4a179fef0553b0f01ab7a5 346 Pfam PF01565 FAD binding domain 38 155 1.5E-20 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 D521_0293 9cdfc2d05e4a179fef0553b0f01ab7a5 346 SUPERFAMILY SSF56194 219 345 1.44E-44 T 14-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0293 9cdfc2d05e4a179fef0553b0f01ab7a5 346 Gene3D G3DSA:3.30.43.10 12 80 5.2E-13 T 14-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 D521_0293 9cdfc2d05e4a179fef0553b0f01ab7a5 346 Gene3D G3DSA:3.30.465.10 83 235 3.9E-55 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 D521_0293 9cdfc2d05e4a179fef0553b0f01ab7a5 346 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 20 342 7.0E-69 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0293 9cdfc2d05e4a179fef0553b0f01ab7a5 346 SUPERFAMILY SSF56176 19 206 2.37E-39 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 D521_0293 9cdfc2d05e4a179fef0553b0f01ab7a5 346 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 346 75.898 T 14-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0688 ed2f930f98b782eca4dfab39c075dbc5 507 Pfam PF05681 Fumarate hydratase (Fumerase) 11 285 2.4E-100 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 D521_0688 ed2f930f98b782eca4dfab39c075dbc5 507 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 327 488 1.7E-46 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 D521_0688 ed2f930f98b782eca4dfab39c075dbc5 507 Gene3D G3DSA:3.20.130.10 305 490 4.2E-57 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 D521_0688 ed2f930f98b782eca4dfab39c075dbc5 507 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 12 284 1.5E-64 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 D521_0688 ed2f930f98b782eca4dfab39c075dbc5 507 PIRSF PIRSF001394 1 507 4.4E-215 T 14-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 D521_0688 ed2f930f98b782eca4dfab39c075dbc5 507 SUPERFAMILY SSF117457 318 489 4.05E-60 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 D521_0688 ed2f930f98b782eca4dfab39c075dbc5 507 Pfam PF05683 Fumarase C-terminus 289 490 3.8E-79 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 Gene3D G3DSA:1.10.1740.60 202 286 3.4E-34 T 14-10-2018 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 SUPERFAMILY SSF63737 7 199 2.35E-38 T 14-10-2018 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 301 316 6.5E-10 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 320 332 6.5E-10 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 133 148 6.5E-10 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 265 275 6.5E-10 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 183 198 6.5E-10 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 Gene3D G3DSA:1.25.50.10 548 868 3.4E-112 T 14-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 551 867 1.5E-116 T 14-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 Gene3D G3DSA:1.10.390.10 287 454 1.0E-68 T 14-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 Gene3D G3DSA:2.60.40.1840 455 547 7.4E-27 T 14-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 SUPERFAMILY SSF55486 214 462 7.43E-73 T 14-10-2018 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 Gene3D G3DSA:2.60.40.1730 16 201 4.0E-67 T 14-10-2018 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 866 0.0 T 14-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 Pfam PF01433 Peptidase family M1 domain 218 449 2.9E-55 T 14-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 D521_0532 394bbc85b7a619927fd01dc60e3a8e8d 872 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 455 547 1.2E-26 T 14-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold D521_0965 f957b79ab4a7343e3c3f5486946aa9a4 116 ProSitePatterns PS00935 Glyoxalase I signature 2. 59 71 - T 14-10-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 D521_0965 f957b79ab4a7343e3c3f5486946aa9a4 116 SUPERFAMILY SSF54593 1 116 6.04E-28 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase D521_0965 f957b79ab4a7343e3c3f5486946aa9a4 116 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 1 113 1.1E-17 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain D521_0965 f957b79ab4a7343e3c3f5486946aa9a4 116 TIGRFAM TIGR00068 glyox_I: lactoylglutathione lyase 2 115 6.0E-54 T 14-10-2018 IPR004361 Glyoxalase I GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 D521_0965 f957b79ab4a7343e3c3f5486946aa9a4 116 Gene3D G3DSA:3.10.180.10 1 116 9.7E-39 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase D521_0711 247e91945e43745b34ba0529291bb7b7 700 SMART SM00849 144 366 1.1E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0711 247e91945e43745b34ba0529291bb7b7 700 Gene3D G3DSA:3.60.15.30 42 401 1.1E-150 T 14-10-2018 D521_0711 247e91945e43745b34ba0529291bb7b7 700 Gene3D G3DSA:3.30.1050.10 545 676 1.8E-34 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily D521_0711 247e91945e43745b34ba0529291bb7b7 700 SUPERFAMILY SSF55718 552 672 3.77E-30 T 14-10-2018 IPR036527 SCP2 sterol-binding domain superfamily D521_0711 247e91945e43745b34ba0529291bb7b7 700 SUPERFAMILY SSF56281 43 543 9.1E-142 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_0711 247e91945e43745b34ba0529291bb7b7 700 Pfam PF14863 Alkyl sulfatase dimerisation 403 541 8.3E-46 T 14-10-2018 IPR029228 Alkyl sulfatase dimerisation domain GO:0046983 D521_0711 247e91945e43745b34ba0529291bb7b7 700 Gene3D G3DSA:1.25.40.880 402 542 4.7E-43 T 14-10-2018 IPR038536 Alkyl/aryl-sulfatase, dimerisation domain superfamily D521_0711 247e91945e43745b34ba0529291bb7b7 700 Pfam PF14864 Alkyl sulfatase C-terminal 550 671 2.0E-33 T 14-10-2018 IPR029229 Alkyl sulfatase, C-terminal D521_0711 247e91945e43745b34ba0529291bb7b7 700 Pfam PF00753 Metallo-beta-lactamase superfamily 140 366 4.1E-36 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0338 671e1d98d3e63ee59aa6cd5c8309bd0a 151 Pfam PF13560 Helix-turn-helix domain 6 60 2.9E-10 T 14-10-2018 D521_0338 671e1d98d3e63ee59aa6cd5c8309bd0a 151 Gene3D G3DSA:1.10.260.40 1 67 4.0E-16 T 14-10-2018 D521_0338 671e1d98d3e63ee59aa6cd5c8309bd0a 151 SUPERFAMILY SSF47413 2 64 2.04E-14 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 D521_0338 671e1d98d3e63ee59aa6cd5c8309bd0a 151 SMART SM00530 9 64 5.1E-10 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 83 122 8.2E-17 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 Gene3D G3DSA:3.40.228.10 346 404 3.1E-13 T 14-10-2018 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 Gene3D G3DSA:3.30.70.20 125 205 4.4E-8 T 14-10-2018 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 75 1.4E-18 T 14-10-2018 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 Gene3D G3DSA:3.10.20.740 1 123 1.8E-41 T 14-10-2018 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 98 110 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 622 2.7E-200 T 14-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 Gene3D G3DSA:3.40.50.740 280 345 3.1E-13 T 14-10-2018 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 SUPERFAMILY SSF54862 75 211 1.05E-35 T 14-10-2018 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 146 156 - T 14-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 SUPERFAMILY SSF54292 1 74 9.34E-20 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 SUPERFAMILY SSF53706 214 646 2.3E-79 T 14-10-2018 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 SMART SM00929 83 123 7.9E-21 T 14-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 Pfam PF00384 Molybdopterin oxidoreductase 273 406 7.3E-18 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 Pfam PF00384 Molybdopterin oxidoreductase 528 622 2.0E-14 T 14-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0752 ce78e532c6240968271d6f9ea07fa281 771 Gene3D G3DSA:3.40.50.740 420 659 1.6E-19 T 14-10-2018 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 PRINTS PR00145 Argininosuccinate lyase family signature 112 134 4.5E-67 T 14-10-2018 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 PRINTS PR00145 Argininosuccinate lyase family signature 153 173 4.5E-67 T 14-10-2018 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 PRINTS PR00145 Argininosuccinate lyase family signature 321 340 4.5E-67 T 14-10-2018 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 PRINTS PR00145 Argininosuccinate lyase family signature 242 266 4.5E-67 T 14-10-2018 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 PRINTS PR00145 Argininosuccinate lyase family signature 204 220 4.5E-67 T 14-10-2018 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 PRINTS PR00145 Argininosuccinate lyase family signature 286 302 4.5E-67 T 14-10-2018 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 Gene3D G3DSA:1.10.275.10 36 240 4.2E-183 T 14-10-2018 IPR024083 Fumarase/histidase, N-terminal D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 ProSitePatterns PS00163 Fumarate lyases signature. 286 295 - T 14-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 Pfam PF14698 Argininosuccinate lyase C-terminal 374 448 1.2E-20 T 14-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 Gene3D G3DSA:1.20.200.10 130 465 4.2E-183 T 14-10-2018 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 TIGRFAM TIGR00838 argH: argininosuccinate lyase 15 471 2.5E-179 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 SUPERFAMILY SSF48557 15 470 5.97E-143 T 14-10-2018 IPR008948 L-Aspartase-like GO:0003824 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 Gene3D G3DSA:1.10.40.30 371 449 4.2E-183 T 14-10-2018 D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 Pfam PF00206 Lyase 18 311 1.1E-73 T 14-10-2018 IPR022761 Fumarate lyase, N-terminal D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 PRINTS PR00149 Fumarate lyase superfamily signature 113 131 3.2E-29 T 14-10-2018 IPR000362 Fumarate lyase family D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 PRINTS PR00149 Fumarate lyase superfamily signature 242 269 3.2E-29 T 14-10-2018 IPR000362 Fumarate lyase family D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 PRINTS PR00149 Fumarate lyase superfamily signature 286 302 3.2E-29 T 14-10-2018 IPR000362 Fumarate lyase family D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 PRINTS PR00149 Fumarate lyase superfamily signature 158 176 3.2E-29 T 14-10-2018 IPR000362 Fumarate lyase family D521_0520 80b5adb1f4effeb38f8433d1d49d9b61 472 Hamap MF_00006 Argininosuccinate lyase [argH]. 13 470 42.385 T 14-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 D521_0485 10307a6ce195757c552e1da2eb5342d0 234 Pfam PF01467 Cytidylyltransferase-like 14 204 2.3E-23 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 D521_0485 10307a6ce195757c552e1da2eb5342d0 234 Gene3D G3DSA:3.40.50.620 6 234 7.8E-54 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0485 10307a6ce195757c552e1da2eb5342d0 234 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 10 234 26.163 T 14-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 D521_0485 10307a6ce195757c552e1da2eb5342d0 234 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 12 69 4.6E-8 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 D521_0485 10307a6ce195757c552e1da2eb5342d0 234 SUPERFAMILY SSF52374 9 233 1.01E-40 T 14-10-2018 D521_1947 2bc5287e3067bd6b1ec7fc48fe044a9f 477 SUPERFAMILY SSF50156 89 183 3.83E-21 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 D521_1947 2bc5287e3067bd6b1ec7fc48fe044a9f 477 Pfam PF13180 PDZ domain 99 178 1.1E-14 T 14-10-2018 IPR001478 PDZ domain GO:0005515 D521_1947 2bc5287e3067bd6b1ec7fc48fe044a9f 477 Gene3D G3DSA:3.90.226.10 187 376 1.3E-92 T 14-10-2018 D521_1947 2bc5287e3067bd6b1ec7fc48fe044a9f 477 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 52 383 1.8E-98 T 14-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 D521_1947 2bc5287e3067bd6b1ec7fc48fe044a9f 477 SMART SM00228 99 170 2.2E-17 T 14-10-2018 IPR001478 PDZ domain GO:0005515 D521_1947 2bc5287e3067bd6b1ec7fc48fe044a9f 477 Gene3D G3DSA:2.30.42.10 99 186 1.3E-92 T 14-10-2018 D521_1947 2bc5287e3067bd6b1ec7fc48fe044a9f 477 Pfam PF03572 Peptidase family S41 197 378 3.9E-54 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 D521_1947 2bc5287e3067bd6b1ec7fc48fe044a9f 477 SMART SM00245 172 379 1.1E-65 T 14-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 D521_1947 2bc5287e3067bd6b1ec7fc48fe044a9f 477 Gene3D G3DSA:3.30.750.44 46 354 1.3E-92 T 14-10-2018 D521_1947 2bc5287e3067bd6b1ec7fc48fe044a9f 477 SUPERFAMILY SSF52096 35 383 2.32E-79 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 Gene3D G3DSA:3.30.70.1430 44 805 3.9E-272 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 Gene3D G3DSA:1.20.1640.10 15 500 3.9E-272 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 SUPERFAMILY SSF82714 708 793 3.53E-17 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 SUPERFAMILY SSF82693 45 127 3.14E-16 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 SUPERFAMILY SSF82693 553 648 2.46E-5 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 Gene3D G3DSA:1.20.1640.10 501 1011 3.9E-272 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 SUPERFAMILY SSF82693 139 325 5.23E-15 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 SUPERFAMILY SSF82866 291 490 3.01E-39 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 Gene3D G3DSA:3.30.2090.10 180 271 3.9E-272 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 SUPERFAMILY SSF82866 792 1017 4.97E-48 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 Pfam PF00873 AcrB/AcrD/AcrF family 11 1014 5.7E-256 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 Gene3D G3DSA:3.30.70.1430 554 657 3.9E-272 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 SUPERFAMILY SSF82714 183 265 1.24E-15 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 Gene3D G3DSA:3.30.70.1440 658 856 3.9E-272 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 PRINTS PR00702 Acriflavin resistance protein family signature 439 462 2.1E-28 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 PRINTS PR00702 Acriflavin resistance protein family signature 332 355 2.1E-28 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 PRINTS PR00702 Acriflavin resistance protein family signature 42 60 2.1E-28 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 PRINTS PR00702 Acriflavin resistance protein family signature 537 554 2.1E-28 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 2.1E-28 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 PRINTS PR00702 Acriflavin resistance protein family signature 14 38 2.1E-28 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 PRINTS PR00702 Acriflavin resistance protein family signature 464 487 2.1E-28 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 Gene3D G3DSA:3.30.2090.10 709 797 3.9E-272 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 Gene3D G3DSA:3.30.70.1320 135 326 3.9E-272 T 14-10-2018 D521_1085 62a82d98dc5cd95f2398e8592f307114 1025 TIGRFAM TIGR00914 2A0601: heavy metal efflux pump, CzcA family 6 1018 1.4E-276 T 14-10-2018 IPR004763 Cation efflux system CzcA/CusA/SilA/NccA/HelA/CnrA GO:0006812|GO:0008324|GO:0016021 D521_0471 24dd65d657f043f5d56673f0b8c799dc 227 SMART SM00345 16 74 4.8E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0471 24dd65d657f043f5d56673f0b8c799dc 227 Gene3D G3DSA:1.20.120.530 77 215 6.8E-28 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal D521_0471 24dd65d657f043f5d56673f0b8c799dc 227 SMART SM00895 84 208 1.3E-16 T 14-10-2018 IPR011711 GntR, C-terminal D521_0471 24dd65d657f043f5d56673f0b8c799dc 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 2.0E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0471 24dd65d657f043f5d56673f0b8c799dc 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 2.0E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0471 24dd65d657f043f5d56673f0b8c799dc 227 SUPERFAMILY SSF46785 5 78 2.77E-19 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0471 24dd65d657f043f5d56673f0b8c799dc 227 SUPERFAMILY SSF48008 80 216 4.97E-24 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal D521_0471 24dd65d657f043f5d56673f0b8c799dc 227 Pfam PF07729 FCD domain 86 207 1.4E-25 T 14-10-2018 IPR011711 GntR, C-terminal D521_0471 24dd65d657f043f5d56673f0b8c799dc 227 Gene3D G3DSA:1.10.10.10 3 74 1.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0471 24dd65d657f043f5d56673f0b8c799dc 227 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 72 5.5E-19 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1873 238768d44051afd8862487e5e703cf94 194 SUPERFAMILY SSF46929 149 192 1.24E-8 T 14-10-2018 IPR036267 RuvA, C-terminal domain superfamily D521_1873 238768d44051afd8862487e5e703cf94 194 Pfam PF14520 Helix-hairpin-helix domain 72 129 1.1E-17 T 14-10-2018 D521_1873 238768d44051afd8862487e5e703cf94 194 SUPERFAMILY SSF47781 65 133 1.0E-21 T 14-10-2018 IPR010994 RuvA domain 2-like D521_1873 238768d44051afd8862487e5e703cf94 194 Pfam PF07499 RuvA, C-terminal domain 148 191 9.8E-12 T 14-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 D521_1873 238768d44051afd8862487e5e703cf94 194 Gene3D G3DSA:1.10.150.20 67 136 3.2E-26 T 14-10-2018 D521_1873 238768d44051afd8862487e5e703cf94 194 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 187 1.3E-56 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 D521_1873 238768d44051afd8862487e5e703cf94 194 Pfam PF01330 RuvA N terminal domain 1 62 7.7E-21 T 14-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 D521_1873 238768d44051afd8862487e5e703cf94 194 Gene3D G3DSA:2.40.50.140 1 66 5.7E-26 T 14-10-2018 D521_1873 238768d44051afd8862487e5e703cf94 194 SUPERFAMILY SSF50249 1 63 1.31E-18 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1873 238768d44051afd8862487e5e703cf94 194 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 191 30.741 T 14-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 D521_1873 238768d44051afd8862487e5e703cf94 194 SMART SM00278 108 127 0.15 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 D521_1873 238768d44051afd8862487e5e703cf94 194 SMART SM00278 73 92 7.8 T 14-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 D521_1873 238768d44051afd8862487e5e703cf94 194 Gene3D G3DSA:1.10.8.10 146 190 1.5E-6 T 14-10-2018 D521_1444 9135223cb8b68341dbba6d71015d15db 116 Pfam PF11953 Domain of unknown function (DUF3470) 75 114 7.8E-18 T 14-10-2018 IPR022569 Ferredoxin, C-terminal D521_1444 9135223cb8b68341dbba6d71015d15db 116 SUPERFAMILY SSF54862 10 106 1.05E-24 T 14-10-2018 D521_1444 9135223cb8b68341dbba6d71015d15db 116 PRINTS PR00354 7Fe ferredoxin signature 28 38 1.2E-15 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 D521_1444 9135223cb8b68341dbba6d71015d15db 116 PRINTS PR00354 7Fe ferredoxin signature 18 28 1.2E-15 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 D521_1444 9135223cb8b68341dbba6d71015d15db 116 PRINTS PR00354 7Fe ferredoxin signature 44 61 1.2E-15 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 D521_1444 9135223cb8b68341dbba6d71015d15db 116 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1444 9135223cb8b68341dbba6d71015d15db 116 Pfam PF00037 4Fe-4S binding domain 43 65 1.7E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1444 9135223cb8b68341dbba6d71015d15db 116 Gene3D G3DSA:3.30.70.20 11 114 2.4E-32 T 14-10-2018 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 SUPERFAMILY SSF52317 165 390 3.36E-61 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 Gene3D G3DSA:3.50.30.20 9 156 2.8E-57 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 11 390 5.1E-146 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 SMART SM01097 9 139 2.5E-89 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 Gene3D G3DSA:3.40.50.880 163 392 6.2E-72 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 9 393 48.775 T 14-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 Pfam PF00117 Glutamine amidotransferase class-I 212 387 5.4E-47 T 14-10-2018 IPR017926 Glutamine amidotransferase D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 SUPERFAMILY SSF52021 10 146 2.62E-55 T 14-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 11 138 9.7E-52 T 14-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 PRINTS PR00096 Glutamine amidotransferase superfamily signature 279 290 3.2E-9 T 14-10-2018 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 PRINTS PR00096 Glutamine amidotransferase superfamily signature 364 377 3.2E-9 T 14-10-2018 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 PRINTS PR00096 Glutamine amidotransferase superfamily signature 251 260 3.2E-9 T 14-10-2018 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 209 223 5.2E-39 T 14-10-2018 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 296 313 5.2E-39 T 14-10-2018 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 279 295 5.2E-39 T 14-10-2018 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 321 332 5.2E-39 T 14-10-2018 D521_0778 ae6090c9f26fd7db0657ad0a1cae038a 400 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 248 262 5.2E-39 T 14-10-2018 D521_0104 e77d88db4e923d885c1eafda4a5a2780 419 SUPERFAMILY SSF55205 2 418 2.78E-134 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 D521_0104 e77d88db4e923d885c1eafda4a5a2780 419 Gene3D G3DSA:3.65.10.10 3 415 1.3E-163 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 D521_0104 e77d88db4e923d885c1eafda4a5a2780 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 3 408 8.4E-107 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 D521_0104 e77d88db4e923d885c1eafda4a5a2780 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 417 1.9E-170 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0104 e77d88db4e923d885c1eafda4a5a2780 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 418 42.549 T 14-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0104 e77d88db4e923d885c1eafda4a5a2780 419 Gene3D G3DSA:3.65.10.10 16 232 1.3E-163 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 D521_1824 c6e926538ad5335a0d4826325929fc82 45 Gene3D G3DSA:3.30.70.640 1 45 4.2E-19 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1824 c6e926538ad5335a0d4826325929fc82 45 SUPERFAMILY SSF55040 1 43 2.62E-18 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1824 c6e926538ad5335a0d4826325929fc82 45 Pfam PF01967 MoaC family 1 38 2.9E-14 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 253 7.0E-25 T 14-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 Gene3D G3DSA:3.40.120.10 250 367 3.9E-44 T 14-10-2018 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 Gene3D G3DSA:3.40.120.10 172 249 6.1E-31 T 14-10-2018 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 100 109 - T 14-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 141 6.6E-35 T 14-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 Gene3D G3DSA:3.30.310.50 368 461 1.9E-25 T 14-10-2018 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 99 113 2.1E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 2.1E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 204 217 2.1E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 2.1E-23 T 14-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 SUPERFAMILY SSF53738 154 255 9.81E-31 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 SUPERFAMILY SSF53738 4 141 1.61E-37 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 258 365 1.2E-23 T 14-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 Gene3D G3DSA:3.40.120.10 3 152 9.3E-55 T 14-10-2018 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 SUPERFAMILY SSF55957 366 452 9.77E-20 T 14-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 383 446 2.3E-10 T 14-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0701 15babba1d4a2e39dd03de863a08e2237 463 SUPERFAMILY SSF53738 258 360 6.28E-34 T 14-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 D521_0573 b1d2e42c3f2b62684d624c6ec7b37764 471 SMART SM00729 63 286 3.0E-49 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 D521_0573 b1d2e42c3f2b62684d624c6ec7b37764 471 Pfam PF04055 Radical SAM superfamily 69 241 3.3E-22 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 D521_0573 b1d2e42c3f2b62684d624c6ec7b37764 471 Pfam PF06969 HemN C-terminal domain 377 444 1.2E-7 T 14-10-2018 IPR010723 HemN, C-terminal D521_0573 b1d2e42c3f2b62684d624c6ec7b37764 471 SUPERFAMILY SSF102114 17 457 3.79E-135 T 14-10-2018 D521_0573 b1d2e42c3f2b62684d624c6ec7b37764 471 Gene3D G3DSA:1.10.10.920 378 471 1.4E-27 T 14-10-2018 D521_0573 b1d2e42c3f2b62684d624c6ec7b37764 471 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 17 470 2.7E-182 T 14-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 D521_0573 b1d2e42c3f2b62684d624c6ec7b37764 471 PIRSF PIRSF000167 14 468 2.5E-161 T 14-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 D521_0573 b1d2e42c3f2b62684d624c6ec7b37764 471 Gene3D G3DSA:3.80.30.20 11 377 4.4E-120 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe D521_0886 8241c3489ffa854028d32f4d62124612 294 SUPERFAMILY SSF53613 10 280 2.03E-72 T 14-10-2018 IPR029056 Ribokinase-like D521_0886 8241c3489ffa854028d32f4d62124612 294 Pfam PF08543 Phosphomethylpyrimidine kinase 21 276 4.4E-85 T 14-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 D521_0886 8241c3489ffa854028d32f4d62124612 294 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 14 278 3.4E-86 T 14-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 D521_0886 8241c3489ffa854028d32f4d62124612 294 Gene3D G3DSA:3.40.1190.20 2 286 1.0E-96 T 14-10-2018 IPR029056 Ribokinase-like D521_1874 561007ecb95690c2baa92f22cf71e747 355 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 268 349 4.0E-35 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 D521_1874 561007ecb95690c2baa92f22cf71e747 355 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 355 181.047 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 D521_1874 561007ecb95690c2baa92f22cf71e747 355 SUPERFAMILY SSF52540 38 269 1.67E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1874 561007ecb95690c2baa92f22cf71e747 355 Gene3D G3DSA:1.10.8.60 200 273 4.8E-32 T 14-10-2018 D521_1874 561007ecb95690c2baa92f22cf71e747 355 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 271 344 1.9E-33 T 14-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 D521_1874 561007ecb95690c2baa92f22cf71e747 355 SUPERFAMILY SSF46785 275 348 1.36E-26 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1874 561007ecb95690c2baa92f22cf71e747 355 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 22 253 9.2E-117 T 14-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 D521_1874 561007ecb95690c2baa92f22cf71e747 355 Gene3D G3DSA:3.40.50.300 36 199 1.1E-40 T 14-10-2018 D521_1874 561007ecb95690c2baa92f22cf71e747 355 Gene3D G3DSA:1.10.10.10 275 355 3.4E-34 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1874 561007ecb95690c2baa92f22cf71e747 355 SMART SM00382 69 196 1.3E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1874 561007ecb95690c2baa92f22cf71e747 355 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 41 344 2.0E-146 T 14-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 D521_1276 d476b8a782705d1be7d786ab364fa9bc 1192 SMART SM00487 100 302 2.0E-20 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_1276 d476b8a782705d1be7d786ab364fa9bc 1192 Pfam PF13020 Domain of unknown function (DUF3883) 1080 1156 4.7E-16 T 14-10-2018 IPR024975 Domain of unknown function DUF3883 D521_1276 d476b8a782705d1be7d786ab364fa9bc 1192 SUPERFAMILY SSF52540 224 667 4.46E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1276 d476b8a782705d1be7d786ab364fa9bc 1192 Pfam PF00176 SNF2 family N-terminal domain 125 358 5.9E-17 T 14-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 D521_1276 d476b8a782705d1be7d786ab364fa9bc 1192 SUPERFAMILY SSF52540 83 296 4.51E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1276 d476b8a782705d1be7d786ab364fa9bc 1192 Gene3D G3DSA:3.40.50.300 440 657 1.5E-40 T 14-10-2018 D521_1276 d476b8a782705d1be7d786ab364fa9bc 1192 Pfam PF00271 Helicase conserved C-terminal domain 525 627 3.9E-21 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1276 d476b8a782705d1be7d786ab364fa9bc 1192 SMART SM00490 542 627 4.0E-25 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1276 d476b8a782705d1be7d786ab364fa9bc 1192 Gene3D G3DSA:3.40.50.10810 101 371 6.0E-60 T 14-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 PIRSF PIRSF006092 1 158 8.6E-53 T 14-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 Gene3D G3DSA:3.10.50.30 80 158 6.7E-29 T 14-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 SUPERFAMILY SSF46557 3 77 1.7E-27 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 SUPERFAMILY SSF54534 83 157 3.4E-23 T 14-10-2018 D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 Pfam PF03449 Transcription elongation factor, N-terminal 4 74 6.0E-31 T 14-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 2.5E-28 T 14-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 32.454 T 14-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 Gene3D G3DSA:1.10.287.180 1 75 2.7E-30 T 14-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 9.3E-55 T 14-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 D521_0780 5a03117a18ae8da18d0453d5b4495e2a 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 14-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 D521_0917 c652876b44da71a0df5e33f598508912 313 Gene3D G3DSA:3.10.290.10 1 54 3.2E-11 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 D521_0917 c652876b44da71a0df5e33f598508912 313 Gene3D G3DSA:3.30.2350.10 56 278 7.6E-66 T 14-10-2018 D521_0917 c652876b44da71a0df5e33f598508912 313 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 116 130 - T 14-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0917 c652876b44da71a0df5e33f598508912 313 SUPERFAMILY SSF55120 59 293 2.47E-68 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0917 c652876b44da71a0df5e33f598508912 313 Pfam PF00849 RNA pseudouridylate synthase 74 227 1.7E-31 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0917 c652876b44da71a0df5e33f598508912 313 SUPERFAMILY SSF55174 1 47 1.55E-5 T 14-10-2018 D521_0917 c652876b44da71a0df5e33f598508912 313 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 1 287 1.3E-80 T 14-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0527 4bc37916a0f1ab66186ee59a6957daf5 211 Gene3D G3DSA:2.30.110.10 1 211 1.2E-84 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 D521_0527 4bc37916a0f1ab66186ee59a6957daf5 211 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 3 211 2.2E-86 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 D521_0527 4bc37916a0f1ab66186ee59a6957daf5 211 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 181 194 - T 14-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 D521_0527 4bc37916a0f1ab66186ee59a6957daf5 211 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 10 211 39.737 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 D521_0527 4bc37916a0f1ab66186ee59a6957daf5 211 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 33 119 1.6E-24 T 14-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 D521_0527 4bc37916a0f1ab66186ee59a6957daf5 211 SUPERFAMILY SSF50475 7 211 2.75E-68 T 14-10-2018 D521_0527 4bc37916a0f1ab66186ee59a6957daf5 211 PIRSF PIRSF000190 1 211 4.3E-82 T 14-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 D521_0527 4bc37916a0f1ab66186ee59a6957daf5 211 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 171 211 1.3E-19 T 14-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 D521_0744 e62dad620c8477d2053f21e90443f23d 252 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 243 5.9E-57 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0744 e62dad620c8477d2053f21e90443f23d 252 Pfam PF00121 Triosephosphate isomerase 5 250 9.7E-82 T 14-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0744 e62dad620c8477d2053f21e90443f23d 252 Gene3D G3DSA:3.20.20.70 1 252 4.9E-89 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0744 e62dad620c8477d2053f21e90443f23d 252 SUPERFAMILY SSF51351 1 251 1.96E-82 T 14-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0744 e62dad620c8477d2053f21e90443f23d 252 ProSitePatterns PS00171 Triosephosphate isomerase active site. 169 179 - T 14-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0744 e62dad620c8477d2053f21e90443f23d 252 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 252 58.836 T 14-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0374 46a47e24a502db187ac7313daf8753dc 164 Pfam PF08212 Lipocalin-like domain 15 162 3.8E-45 T 14-10-2018 IPR000566 Lipocalin/cytosolic fatty-acid binding domain D521_0374 46a47e24a502db187ac7313daf8753dc 164 SUPERFAMILY SSF50814 7 163 2.77E-39 T 14-10-2018 IPR012674 Calycin D521_0374 46a47e24a502db187ac7313daf8753dc 164 PRINTS PR01171 Bacterial lipocalin signature 52 61 1.2E-7 T 14-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 D521_0374 46a47e24a502db187ac7313daf8753dc 164 PRINTS PR01171 Bacterial lipocalin signature 124 135 1.2E-7 T 14-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 D521_0374 46a47e24a502db187ac7313daf8753dc 164 PRINTS PR01171 Bacterial lipocalin signature 15 29 1.2E-7 T 14-10-2018 IPR002446 Lipocalin, bacterial GO:0005215 D521_0374 46a47e24a502db187ac7313daf8753dc 164 Gene3D G3DSA:2.40.128.20 1 164 4.3E-47 T 14-10-2018 IPR012674 Calycin D521_0374 46a47e24a502db187ac7313daf8753dc 164 PIRSF PIRSF036893 1 164 2.2E-50 T 14-10-2018 IPR022271 Lipocalin, ApoD type D521_1754 c80f7bb9c8dfdd722714673c3a48e4b2 340 Gene3D G3DSA:3.30.390.60 125 224 8.3E-37 T 14-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily D521_1754 c80f7bb9c8dfdd722714673c3a48e4b2 340 SUPERFAMILY SSF55781 70 336 2.94E-58 T 14-10-2018 D521_1754 c80f7bb9c8dfdd722714673c3a48e4b2 340 SUPERFAMILY SSF46785 1 84 1.86E-22 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1754 c80f7bb9c8dfdd722714673c3a48e4b2 340 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 6 72 1.4E-5 T 14-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 D521_1754 c80f7bb9c8dfdd722714673c3a48e4b2 340 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 2 332 2.8E-89 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 D521_1754 c80f7bb9c8dfdd722714673c3a48e4b2 340 PIRSF PIRSF005485 1 338 1.3E-102 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 D521_1754 c80f7bb9c8dfdd722714673c3a48e4b2 340 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 327 26.296 T 14-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 D521_1754 c80f7bb9c8dfdd722714673c3a48e4b2 340 Gene3D G3DSA:1.10.10.10 1 82 1.1E-30 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1754 c80f7bb9c8dfdd722714673c3a48e4b2 340 Pfam PF01628 HrcA protein C terminal domain 102 320 3.7E-55 T 14-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 D521_1754 c80f7bb9c8dfdd722714673c3a48e4b2 340 Gene3D G3DSA:3.30.450.40 102 332 8.3E-37 T 14-10-2018 IPR029016 GAF-like domain superfamily D521_1066 b1c4b5790cb1296e64449c5e5910c19f 446 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 13 444 6.9E-174 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 D521_1066 b1c4b5790cb1296e64449c5e5910c19f 446 SMART SM00788 11 439 4.9E-292 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 D521_1066 b1c4b5790cb1296e64449c5e5910c19f 446 Gene3D G3DSA:3.90.170.10 274 446 1.5E-68 T 14-10-2018 D521_1066 b1c4b5790cb1296e64449c5e5910c19f 446 Gene3D G3DSA:1.10.300.10 109 208 3.6E-101 T 14-10-2018 D521_1066 b1c4b5790cb1296e64449c5e5910c19f 446 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 18 25 - T 14-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 D521_1066 b1c4b5790cb1296e64449c5e5910c19f 446 Gene3D G3DSA:3.40.440.10 13 256 3.6E-101 T 14-10-2018 D521_1066 b1c4b5790cb1296e64449c5e5910c19f 446 Pfam PF00709 Adenylosuccinate synthetase 12 438 1.7E-176 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 D521_1066 b1c4b5790cb1296e64449c5e5910c19f 446 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 446 211.706 T 14-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 D521_1066 b1c4b5790cb1296e64449c5e5910c19f 446 SUPERFAMILY SSF52540 11 444 1.59E-171 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1066 b1c4b5790cb1296e64449c5e5910c19f 446 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 140 151 - T 14-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 D521_1535 fe2cba27d75cc8e4291a060d327353b9 396 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 4 114 5.7E-18 T 14-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI D521_1535 fe2cba27d75cc8e4291a060d327353b9 396 Gene3D G3DSA:1.25.40.10 133 272 5.1E-21 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1535 fe2cba27d75cc8e4291a060d327353b9 396 SUPERFAMILY SSF48452 146 274 8.09E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0766 1fc44cf3526ff968e2f8a3042d51936e 506 Gene3D G3DSA:3.40.309.10 258 459 6.6E-152 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 D521_0766 1fc44cf3526ff968e2f8a3042d51936e 506 Gene3D G3DSA:3.40.605.10 32 467 6.6E-152 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 D521_0766 1fc44cf3526ff968e2f8a3042d51936e 506 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 14 490 3.7E-209 T 14-10-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00640+1.2.1.27|MetaCyc: PWY-5642|Reactome: R-HSA-70895 D521_0766 1fc44cf3526ff968e2f8a3042d51936e 506 SUPERFAMILY SSF53720 11 491 4.19E-151 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 D521_0766 1fc44cf3526ff968e2f8a3042d51936e 506 Pfam PF00171 Aldehyde dehydrogenase family 25 486 1.0E-143 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 D521_0962 e5c9e086e1930b2875a693bb9a5828c5 182 Hamap MF_00189 Probable intracellular septation protein A [yciB]. 1 180 18.276 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 D521_0962 e5c9e086e1930b2875a693bb9a5828c5 182 Pfam PF04279 Intracellular septation protein A 1 179 1.5E-67 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 D521_0962 e5c9e086e1930b2875a693bb9a5828c5 182 TIGRFAM TIGR00997 ispZ: intracellular septation protein A 1 179 1.5E-56 T 14-10-2018 IPR006008 Intracellular septation protein A GO:0016021 D521_0604 3066199d28075d57caa44d3a62e1d062 227 Gene3D G3DSA:3.90.1720.10 26 193 1.8E-36 T 14-10-2018 D521_0604 3066199d28075d57caa44d3a62e1d062 227 SUPERFAMILY SSF54001 75 199 2.06E-36 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily D521_0604 3066199d28075d57caa44d3a62e1d062 227 Pfam PF00877 NlpC/P60 family 91 198 9.2E-24 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain D521_1777 4a79b1e99074522ded694027b6f66b8c 204 Gene3D G3DSA:1.20.1050.10 79 193 3.0E-72 T 14-10-2018 D521_1777 4a79b1e99074522ded694027b6f66b8c 204 SUPERFAMILY SSF47616 73 202 2.23E-26 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily D521_1777 4a79b1e99074522ded694027b6f66b8c 204 Pfam PF00043 Glutathione S-transferase, C-terminal domain 123 194 4.4E-10 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal D521_1777 4a79b1e99074522ded694027b6f66b8c 204 Gene3D G3DSA:3.40.30.10 3 197 3.0E-72 T 14-10-2018 D521_1777 4a79b1e99074522ded694027b6f66b8c 204 Pfam PF13417 Glutathione S-transferase, N-terminal domain 3 75 9.7E-16 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 D521_1777 4a79b1e99074522ded694027b6f66b8c 204 SUPERFAMILY SSF52833 1 99 1.01E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0253 ab6d47e2bb914ae465dff472932e1165 320 Pfam PF04321 RmlD substrate binding domain 1 286 1.5E-79 T 14-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 D521_0253 ab6d47e2bb914ae465dff472932e1165 320 Gene3D G3DSA:3.40.50.720 3 286 1.5E-84 T 14-10-2018 D521_0253 ab6d47e2bb914ae465dff472932e1165 320 SUPERFAMILY SSF51735 1 285 4.17E-74 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0253 ab6d47e2bb914ae465dff472932e1165 320 Gene3D G3DSA:3.90.25.10 170 276 1.5E-84 T 14-10-2018 D521_0253 ab6d47e2bb914ae465dff472932e1165 320 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 3 286 1.9E-79 T 14-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 197 4.8E-17 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 2.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 2.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 2.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 Pfam PF00072 Response regulator receiver domain 5 114 5.9E-24 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 SMART SM00448 3 116 5.5E-23 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 Gene3D G3DSA:3.40.50.12740 4 205 9.2E-48 T 14-10-2018 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 SUPERFAMILY SSF46894 140 205 3.74E-17 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 SMART SM00421 142 199 2.7E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1803 667dcae6e7930c5d1874b4c09b49db08 207 SUPERFAMILY SSF52172 2 126 3.13E-26 T 14-10-2018 IPR011006 CheY-like superfamily D521_0919 1703b37ed959b3300c05a7b3b8e581a5 544 SUPERFAMILY SSF53474 192 467 3.97E-35 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0919 1703b37ed959b3300c05a7b3b8e581a5 544 TIGRFAM TIGR01838 PHA_synth_I: poly(R)-hydroxyalkanoic acid synthase, class I 33 537 2.7E-218 T 14-10-2018 IPR010963 Poly(R)-hydroxyalkanoic acid synthase, class I GO:0005737|GO:0016746|GO:0042619 D521_0919 1703b37ed959b3300c05a7b3b8e581a5 544 Pfam PF07167 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus 50 216 4.2E-65 T 14-10-2018 IPR010941 Poly-beta-hydroxybutyrate polymerase, N-terminal domain GO:0042619 D521_0627 d3694380c4a28ce61ed5903ace7f6ac1 252 PIRSF PIRSF004846 2 252 3.0E-55 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 D521_0627 d3694380c4a28ce61ed5903ace7f6ac1 252 Gene3D G3DSA:3.40.190.10 28 248 7.7E-61 T 14-10-2018 D521_0627 d3694380c4a28ce61ed5903ace7f6ac1 252 Gene3D G3DSA:3.40.190.10 102 212 7.7E-61 T 14-10-2018 D521_0627 d3694380c4a28ce61ed5903ace7f6ac1 252 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 29 247 1.6E-51 T 14-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 D521_0627 d3694380c4a28ce61ed5903ace7f6ac1 252 Pfam PF13531 Bacterial extracellular solute-binding protein 25 248 2.1E-38 T 14-10-2018 D521_0627 d3694380c4a28ce61ed5903ace7f6ac1 252 SUPERFAMILY SSF53850 22 251 2.79E-50 T 14-10-2018 D521_2093 8a92c8f655f6afc1167e17b4f5fed8da 50 SUPERFAMILY SSF46785 5 45 2.99E-7 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_2093 8a92c8f655f6afc1167e17b4f5fed8da 50 Gene3D G3DSA:1.10.10.10 3 50 2.2E-7 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1081 35aa534901043a20269626d6cd02f2e6 273 Gene3D G3DSA:3.30.420.10 4 223 1.3E-21 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_1081 35aa534901043a20269626d6cd02f2e6 273 SUPERFAMILY SSF53098 3 235 1.05E-44 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1081 35aa534901043a20269626d6cd02f2e6 273 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 47 267 3.9E-92 T 14-10-2018 IPR019288 Predicted 3'-5' exonuclease, PolB-like D521_1743 6a03463a97082fbda8827b8681e1b1ca 350 Gene3D G3DSA:3.30.1330.10 11 175 2.2E-68 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily D521_1743 6a03463a97082fbda8827b8681e1b1ca 350 Pfam PF00586 AIR synthase related protein, N-terminal domain 64 169 1.3E-14 T 14-10-2018 IPR016188 PurM-like, N-terminal domain D521_1743 6a03463a97082fbda8827b8681e1b1ca 350 Gene3D G3DSA:3.90.650.10 177 350 1.2E-68 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily D521_1743 6a03463a97082fbda8827b8681e1b1ca 350 SUPERFAMILY SSF56042 177 345 2.69E-60 T 14-10-2018 IPR036676 PurM-like, C-terminal domain superfamily D521_1743 6a03463a97082fbda8827b8681e1b1ca 350 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 12 349 46.287 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_1743 6a03463a97082fbda8827b8681e1b1ca 350 Pfam PF02769 AIR synthase related protein, C-terminal domain 182 342 1.3E-37 T 14-10-2018 IPR010918 PurM-like, C-terminal domain D521_1743 6a03463a97082fbda8827b8681e1b1ca 350 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 12 339 1.4E-138 T 14-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_1743 6a03463a97082fbda8827b8681e1b1ca 350 SUPERFAMILY SSF55326 12 175 3.66E-52 T 14-10-2018 IPR036921 PurM-like, N-terminal domain superfamily D521_1666 1c61ef1545ecf3df145f2fa9ae7054e3 422 SUPERFAMILY SSF56059 86 399 1.15E-7 T 14-10-2018 D521_1330 44a93a7a68a6edbf81cf88d3854adefb 215 SMART SM00345 2 45 3.7E-8 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1330 44a93a7a68a6edbf81cf88d3854adefb 215 Pfam PF00392 Bacterial regulatory proteins, gntR family 2 45 1.7E-13 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1330 44a93a7a68a6edbf81cf88d3854adefb 215 SUPERFAMILY SSF46785 2 48 5.73E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1330 44a93a7a68a6edbf81cf88d3854adefb 215 SMART SM00866 66 208 1.2E-21 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 D521_1330 44a93a7a68a6edbf81cf88d3854adefb 215 SUPERFAMILY SSF64288 33 212 5.97E-35 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily D521_1330 44a93a7a68a6edbf81cf88d3854adefb 215 Gene3D G3DSA:1.10.10.10 1 49 9.3E-15 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1330 44a93a7a68a6edbf81cf88d3854adefb 215 Gene3D G3DSA:3.40.1410.10 54 213 6.3E-39 T 14-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily D521_1330 44a93a7a68a6edbf81cf88d3854adefb 215 Pfam PF07702 UTRA domain 71 207 8.6E-29 T 14-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 D521_1330 44a93a7a68a6edbf81cf88d3854adefb 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 19 35 2.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_1330 44a93a7a68a6edbf81cf88d3854adefb 215 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 5 19 2.6E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0073 3444c207905f6c31edd1e1fd98522e04 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 3.9E-27 T 14-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 D521_0073 3444c207905f6c31edd1e1fd98522e04 72 SUPERFAMILY SSF50249 1 70 1.69E-27 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_0073 3444c207905f6c31edd1e1fd98522e04 72 Gene3D G3DSA:2.40.50.140 1 72 3.4E-37 T 14-10-2018 D521_0073 3444c207905f6c31edd1e1fd98522e04 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 26.674 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 D521_0073 3444c207905f6c31edd1e1fd98522e04 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 6.1E-37 T 14-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 D521_0073 3444c207905f6c31edd1e1fd98522e04 72 SMART SM00316 2 72 0.0072 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_0140 efb4b2be25c9dee437fcf62d0677c2b6 594 PIRSF PIRSF016493 8 594 2.9E-168 T 14-10-2018 IPR024191 Peptidase M61 D521_0140 efb4b2be25c9dee437fcf62d0677c2b6 594 SMART SM00228 501 570 0.0013 T 14-10-2018 IPR001478 PDZ domain GO:0005515 D521_0140 efb4b2be25c9dee437fcf62d0677c2b6 594 Gene3D G3DSA:2.30.42.10 501 591 2.2E-12 T 14-10-2018 D521_0140 efb4b2be25c9dee437fcf62d0677c2b6 594 Gene3D G3DSA:1.10.390.60 190 468 6.1E-93 T 14-10-2018 D521_0140 efb4b2be25c9dee437fcf62d0677c2b6 594 Gene3D G3DSA:2.60.40.3650 11 189 8.2E-54 T 14-10-2018 D521_0140 efb4b2be25c9dee437fcf62d0677c2b6 594 SUPERFAMILY SSF50156 503 586 1.45E-10 T 14-10-2018 IPR036034 PDZ superfamily GO:0005515 D521_0140 efb4b2be25c9dee437fcf62d0677c2b6 594 SUPERFAMILY SSF55486 228 435 1.68E-7 T 14-10-2018 D521_0140 efb4b2be25c9dee437fcf62d0677c2b6 594 Pfam PF05299 M61 glycyl aminopeptidase 288 404 8.0E-41 T 14-10-2018 IPR007963 Peptidase M61, catalytic domain D521_0836 45da4ad846530775588e07645c4fffbb 157 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 68 152 1.8E-37 T 14-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 D521_0836 45da4ad846530775588e07645c4fffbb 157 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 154 7.7E-60 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 D521_0836 45da4ad846530775588e07645c4fffbb 157 SUPERFAMILY SSF55200 67 155 2.09E-33 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 D521_0836 45da4ad846530775588e07645c4fffbb 157 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 61 1.9E-22 T 14-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 D521_0836 45da4ad846530775588e07645c4fffbb 157 Gene3D G3DSA:3.10.20.80 1 60 2.5E-23 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 D521_0836 45da4ad846530775588e07645c4fffbb 157 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 155 25.41 T 14-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 D521_0836 45da4ad846530775588e07645c4fffbb 157 ProSitePatterns PS00938 Initiation factor 3 signature. 43 56 - T 14-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 D521_0836 45da4ad846530775588e07645c4fffbb 157 SUPERFAMILY SSF54364 1 62 2.35E-21 T 14-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 D521_0836 45da4ad846530775588e07645c4fffbb 157 Gene3D G3DSA:3.30.110.10 61 156 4.2E-36 T 14-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 D521_0885 e76c79dab90a62eb760a04b8b567b77a 203 Gene3D G3DSA:3.20.20.150 1 194 1.1E-46 T 14-10-2018 D521_0885 e76c79dab90a62eb760a04b8b567b77a 203 Pfam PF01261 Xylose isomerase-like TIM barrel 21 182 6.6E-24 T 14-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain D521_0885 e76c79dab90a62eb760a04b8b567b77a 203 SUPERFAMILY SSF51658 1 183 2.49E-51 T 14-10-2018 IPR036237 Xylose isomerase-like superfamily D521_0724 b5591279c9734e939c3ba21c944b5764 255 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0724 b5591279c9734e939c3ba21c944b5764 255 Gene3D G3DSA:3.40.50.300 5 255 1.2E-58 T 14-10-2018 D521_0724 b5591279c9734e939c3ba21c944b5764 255 SMART SM00382 32 221 1.6E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0724 b5591279c9734e939c3ba21c944b5764 255 Pfam PF00005 ABC transporter 23 172 1.2E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0724 b5591279c9734e939c3ba21c944b5764 255 SUPERFAMILY SSF52540 7 245 2.72E-57 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1761 9cf3a9c8003ffd5fd27b3a596eef2bfe 374 SUPERFAMILY SSF51569 23 369 1.04E-130 T 14-10-2018 D521_1761 9cf3a9c8003ffd5fd27b3a596eef2bfe 374 PIRSF PIRSF001361 10 373 6.0E-160 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 D521_1761 9cf3a9c8003ffd5fd27b3a596eef2bfe 374 Gene3D G3DSA:3.20.20.70 17 371 7.7E-160 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1761 9cf3a9c8003ffd5fd27b3a596eef2bfe 374 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 22 370 1.0E-161 T 14-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 D521_1761 9cf3a9c8003ffd5fd27b3a596eef2bfe 374 Pfam PF00793 DAHP synthetase I family 61 359 2.0E-102 T 14-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 D521_1016 2c6ebfc7bf9267a48184bf561bd6bbea 403 Pfam PF11062 Protein of unknown function (DUF2863) 5 402 2.9E-161 T 14-10-2018 IPR021292 Protein of unknown function DUF2863 D521_1756 b53869cc4913e4e20c21c749c9531b9d 556 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 555 6.9E-154 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 D521_1756 b53869cc4913e4e20c21c749c9531b9d 556 SUPERFAMILY SSF52540 1 517 2.67E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1756 b53869cc4913e4e20c21c749c9531b9d 556 Gene3D G3DSA:3.40.50.300 1 274 7.1E-46 T 14-10-2018 D521_1756 b53869cc4913e4e20c21c749c9531b9d 556 Gene3D G3DSA:3.40.50.300 276 555 1.1E-55 T 14-10-2018 D521_1756 b53869cc4913e4e20c21c749c9531b9d 556 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 513 8.4E-21 T 14-10-2018 IPR003395 RecF/RecN/SMC, N-terminal D521_1756 b53869cc4913e4e20c21c749c9531b9d 556 PIRSF PIRSF003128 1 556 2.9E-155 T 14-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 D521_0371 fb54f5dfe65cb3cd2cd04f837ecf42a9 215 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 41 203 6.7E-6 T 14-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 D521_1269 7c29529aae141a33148cbbb5060af5d5 383 Gene3D G3DSA:3.40.630.10 7 369 2.7E-123 T 14-10-2018 D521_1269 7c29529aae141a33148cbbb5060af5d5 383 Pfam PF01546 Peptidase family M20/M25/M40 70 379 1.7E-43 T 14-10-2018 IPR002933 Peptidase M20 GO:0016787 D521_1269 7c29529aae141a33148cbbb5060af5d5 383 SUPERFAMILY SSF55031 187 294 2.84E-28 T 14-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain D521_1269 7c29529aae141a33148cbbb5060af5d5 383 Pfam PF07687 Peptidase dimerisation domain 183 287 1.3E-25 T 14-10-2018 IPR011650 Peptidase M20, dimerisation domain D521_1269 7c29529aae141a33148cbbb5060af5d5 383 SUPERFAMILY SSF53187 3 381 1.34E-62 T 14-10-2018 D521_1269 7c29529aae141a33148cbbb5060af5d5 383 Hamap MF_01690 Succinyl-diaminopimelate desuccinylase [dapE]. 2 383 50.331 T 14-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 D521_1269 7c29529aae141a33148cbbb5060af5d5 383 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 69 78 - T 14-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 D521_1269 7c29529aae141a33148cbbb5060af5d5 383 TIGRFAM TIGR01246 dapE_proteo: succinyl-diaminopimelate desuccinylase 5 381 1.5E-155 T 14-10-2018 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 D521_1269 7c29529aae141a33148cbbb5060af5d5 383 Gene3D G3DSA:3.30.70.360 187 300 2.7E-123 T 14-10-2018 D521_1731 b7cc9f22d1d8f407c20953c78d937fa6 115 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 14 110 27.365 T 14-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS D521_1731 b7cc9f22d1d8f407c20953c78d937fa6 115 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 33 111 1.1E-31 T 14-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 D521_1731 b7cc9f22d1d8f407c20953c78d937fa6 115 SUPERFAMILY SSF54736 29 114 1.46E-30 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like D521_1731 b7cc9f22d1d8f407c20953c78d937fa6 115 Gene3D G3DSA:3.30.1390.10 11 115 2.1E-41 T 14-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like D521_1051 cea6e0dc7ba2c62afa2133c99460b1dd 454 PIRSF PIRSF000423 11 454 1.8E-170 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 D521_1051 cea6e0dc7ba2c62afa2133c99460b1dd 454 Pfam PF00696 Amino acid kinase family 38 279 1.3E-20 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 D521_1051 cea6e0dc7ba2c62afa2133c99460b1dd 454 Pfam PF00583 Acetyltransferase (GNAT) family 349 418 1.1E-9 T 14-10-2018 IPR000182 GNAT domain D521_1051 cea6e0dc7ba2c62afa2133c99460b1dd 454 SUPERFAMILY SSF55729 311 434 1.47E-18 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_1051 cea6e0dc7ba2c62afa2133c99460b1dd 454 SUPERFAMILY SSF53633 18 303 3.49E-57 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily D521_1051 cea6e0dc7ba2c62afa2133c99460b1dd 454 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 454 187.244 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 D521_1051 cea6e0dc7ba2c62afa2133c99460b1dd 454 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 21 454 7.6E-175 T 14-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 D521_1051 cea6e0dc7ba2c62afa2133c99460b1dd 454 Gene3D G3DSA:3.40.1160.10 20 306 3.2E-80 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily D521_1051 cea6e0dc7ba2c62afa2133c99460b1dd 454 Gene3D G3DSA:3.40.630.30 307 454 2.4E-36 T 14-10-2018 D521_1813 8ecdfaff8ca4715cfd9e373e7156a231 305 Gene3D G3DSA:3.20.10.10 128 293 7.2E-56 T 14-10-2018 D521_1813 8ecdfaff8ca4715cfd9e373e7156a231 305 Pfam PF01063 Amino-transferase class IV 34 264 1.7E-53 T 14-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 D521_1813 8ecdfaff8ca4715cfd9e373e7156a231 305 Gene3D G3DSA:3.30.470.10 1 127 6.9E-40 T 14-10-2018 D521_1813 8ecdfaff8ca4715cfd9e373e7156a231 305 SUPERFAMILY SSF56752 1 301 3.79E-102 T 14-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 D521_1813 8ecdfaff8ca4715cfd9e373e7156a231 305 ProSitePatterns PS00770 Aminotransferases class-IV signature. 192 220 - T 14-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 D521_1813 8ecdfaff8ca4715cfd9e373e7156a231 305 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 9 304 5.8E-132 T 14-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 Gene3D G3DSA:3.40.50.720 1 258 3.8E-80 T 14-10-2018 D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 Pfam PF00106 short chain dehydrogenase 7 197 3.2E-56 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 1.1E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 SUPERFAMILY SSF51735 5 257 1.36E-75 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 4.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 4.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 4.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 4.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 4.8E-40 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1165 fc39cbb7c0333a377fff9d776ac3b2d9 258 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 7 258 6.0E-108 T 14-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 D521_0076 6249e5f5509ab6b2cf11751d0a3613a1 135 Gene3D G3DSA:3.30.420.80 7 135 6.7E-55 T 14-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 D521_0076 6249e5f5509ab6b2cf11751d0a3613a1 135 SUPERFAMILY SSF53137 19 135 6.54E-47 T 14-10-2018 D521_0076 6249e5f5509ab6b2cf11751d0a3613a1 135 PIRSF PIRSF002131 3 135 1.1E-54 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 D521_0076 6249e5f5509ab6b2cf11751d0a3613a1 135 ProSitePatterns PS00054 Ribosomal protein S11 signature. 103 125 - T 14-10-2018 IPR018102 Ribosomal S11, conserved site D521_0076 6249e5f5509ab6b2cf11751d0a3613a1 135 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 135 32.982 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 D521_0076 6249e5f5509ab6b2cf11751d0a3613a1 135 Pfam PF00411 Ribosomal protein S11 25 134 6.9E-51 T 14-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 D521_0076 6249e5f5509ab6b2cf11751d0a3613a1 135 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 16 132 1.7E-56 T 14-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0714 95281cecc78bee065a6194986a47fc39 267 Gene3D G3DSA:3.90.226.10 2 212 1.2E-43 T 14-10-2018 D521_0714 95281cecc78bee065a6194986a47fc39 267 Gene3D G3DSA:1.10.12.10 217 267 3.0E-6 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal D521_0714 95281cecc78bee065a6194986a47fc39 267 Pfam PF00378 Enoyl-CoA hydratase/isomerase 23 266 1.4E-35 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 D521_0714 95281cecc78bee065a6194986a47fc39 267 SUPERFAMILY SSF52096 14 266 6.55E-55 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_0714 95281cecc78bee065a6194986a47fc39 267 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 111 131 - T 14-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 D521_1889 8ebe1c3885a5814d4fa7a4d92ae70fca 528 SUPERFAMILY SSF56112 91 440 1.74E-37 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily D521_1889 8ebe1c3885a5814d4fa7a4d92ae70fca 528 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 5 449 1.6E-164 T 14-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 D521_1889 8ebe1c3885a5814d4fa7a4d92ae70fca 528 Pfam PF03109 ABC1 family 109 235 2.0E-27 T 14-10-2018 IPR004147 UbiB domain D521_0772 e11a892ce5931fde0089a501add83167 460 Gene3D G3DSA:2.40.50.100 135 278 1.2E-79 T 14-10-2018 D521_0772 e11a892ce5931fde0089a501add83167 460 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 112 437 2.1E-62 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 D521_0772 e11a892ce5931fde0089a501add83167 460 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 134 357 5.1E-12 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain D521_0772 e11a892ce5931fde0089a501add83167 460 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 371 392 3.2E-5 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 D521_0772 e11a892ce5931fde0089a501add83167 460 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 147 167 3.2E-5 T 14-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 D521_0772 e11a892ce5931fde0089a501add83167 460 Gene3D G3DSA:2.40.30.170 123 367 1.2E-79 T 14-10-2018 D521_0772 e11a892ce5931fde0089a501add83167 460 SUPERFAMILY SSF111369 125 362 1.31E-47 T 14-10-2018 D521_0772 e11a892ce5931fde0089a501add83167 460 Gene3D G3DSA:1.10.287.470 170 229 1.2E-79 T 14-10-2018 D521_0772 e11a892ce5931fde0089a501add83167 460 Gene3D G3DSA:2.40.420.20 368 435 1.2E-79 T 14-10-2018 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 SUPERFAMILY SSF52540 64 284 1.47E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1271 271c56c3b96ced71070dc76da45ee36f 454 SMART SM00382 86 240 2.7E-8 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1271 271c56c3b96ced71070dc76da45ee36f 454 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 358 450 2.6E-5 T 14-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 Gene3D G3DSA:3.40.50.300 62 281 2.0E-42 T 14-10-2018 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 Gene3D G3DSA:3.30.230.10 323 454 8.1E-18 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup D521_1271 271c56c3b96ced71070dc76da45ee36f 454 PRINTS PR01874 DNA repair protein radA signature 318 341 2.6E-92 T 14-10-2018 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 PRINTS PR01874 DNA repair protein radA signature 170 194 2.6E-92 T 14-10-2018 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 PRINTS PR01874 DNA repair protein radA signature 10 34 2.6E-92 T 14-10-2018 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 PRINTS PR01874 DNA repair protein radA signature 78 106 2.6E-92 T 14-10-2018 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 PRINTS PR01874 DNA repair protein radA signature 209 237 2.6E-92 T 14-10-2018 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 PRINTS PR01874 DNA repair protein radA signature 120 137 2.6E-92 T 14-10-2018 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 PRINTS PR01874 DNA repair protein radA signature 244 270 2.6E-92 T 14-10-2018 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 SUPERFAMILY SSF54211 251 450 3.38E-40 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_1271 271c56c3b96ced71070dc76da45ee36f 454 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 447 6.0E-191 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 Pfam PF13481 AAA domain 80 218 4.3E-14 T 14-10-2018 D521_1271 271c56c3b96ced71070dc76da45ee36f 454 Hamap MF_01498 DNA repair protein RadA [radA]. 21 451 43.426 T 14-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 D521_0470 510579397afe91644b242f1bc91f45a3 1029 Pfam PF13183 4Fe-4S dicluster domain 590 671 2.2E-10 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_0470 510579397afe91644b242f1bc91f45a3 1029 SUPERFAMILY SSF56176 18 277 5.61E-59 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 D521_0470 510579397afe91644b242f1bc91f45a3 1029 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 657 668 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_0470 510579397afe91644b242f1bc91f45a3 1029 Gene3D G3DSA:3.40.462.40 277 330 1.7E-5 T 14-10-2018 D521_0470 510579397afe91644b242f1bc91f45a3 1029 Gene3D G3DSA:3.30.465.40 248 276 1.7E-5 T 14-10-2018 D521_0470 510579397afe91644b242f1bc91f45a3 1029 Gene3D G3DSA:3.30.465.40 16 213 1.6E-42 T 14-10-2018 D521_0470 510579397afe91644b242f1bc91f45a3 1029 SUPERFAMILY SSF55103 251 532 2.62E-58 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 D521_0470 510579397afe91644b242f1bc91f45a3 1029 Pfam PF02913 FAD linked oxidases, C-terminal domain 276 530 1.7E-47 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 D521_0470 510579397afe91644b242f1bc91f45a3 1029 SUPERFAMILY SSF46548 586 676 2.14E-9 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_0470 510579397afe91644b242f1bc91f45a3 1029 Pfam PF01565 FAD binding domain 53 188 2.1E-35 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 D521_1091 9f7267ec381dce766f7be773fc1e7185 204 SMART SM00493 84 173 4.1E-8 T 14-10-2018 IPR006171 TOPRIM domain D521_1091 9f7267ec381dce766f7be773fc1e7185 204 SUPERFAMILY SSF111304 9 204 5.23E-71 T 14-10-2018 IPR023627 Recombination protein RecR D521_1091 9f7267ec381dce766f7be773fc1e7185 204 Hamap MF_00017 Recombination protein RecR [recR]. 1 204 93.611 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 D521_1091 9f7267ec381dce766f7be773fc1e7185 204 Pfam PF13662 Toprim domain 85 179 1.6E-20 T 14-10-2018 IPR006171 TOPRIM domain D521_1091 9f7267ec381dce766f7be773fc1e7185 204 Gene3D G3DSA:1.10.8.420 7 56 5.5E-17 T 14-10-2018 D521_1091 9f7267ec381dce766f7be773fc1e7185 204 Gene3D G3DSA:3.40.1360.10 81 204 3.2E-40 T 14-10-2018 D521_1091 9f7267ec381dce766f7be773fc1e7185 204 Pfam PF02132 RecR protein 45 82 5.1E-13 T 14-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger D521_1091 9f7267ec381dce766f7be773fc1e7185 204 TIGRFAM TIGR00615 recR: recombination protein RecR 9 204 6.7E-70 T 14-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 D521_1124 f6e9f70212463224525cffe602df9e53 130 Gene3D G3DSA:1.10.760.10 22 100 1.3E-27 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1124 f6e9f70212463224525cffe602df9e53 130 SUPERFAMILY SSF46626 22 98 4.01E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1124 f6e9f70212463224525cffe602df9e53 130 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 22 96 3.1E-14 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1124 f6e9f70212463224525cffe602df9e53 130 PRINTS PR00607 Class IE cytochrome C signature 32 43 2.7E-11 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 D521_1124 f6e9f70212463224525cffe602df9e53 130 PRINTS PR00607 Class IE cytochrome C signature 43 53 2.7E-11 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 D521_1124 f6e9f70212463224525cffe602df9e53 130 PRINTS PR00607 Class IE cytochrome C signature 86 97 2.7E-11 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 D521_1124 f6e9f70212463224525cffe602df9e53 130 PRINTS PR00607 Class IE cytochrome C signature 71 83 2.7E-11 T 14-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 D521_1035 87f5dc5e6ac516c4930737a507588a22 433 Gene3D G3DSA:2.40.50.100 3 83 1.7E-20 T 14-10-2018 D521_1035 87f5dc5e6ac516c4930737a507588a22 433 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 205 431 2.3E-78 T 14-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 D521_1035 87f5dc5e6ac516c4930737a507588a22 433 Pfam PF00364 Biotin-requiring enzyme 6 77 8.3E-21 T 14-10-2018 IPR000089 Biotin/lipoyl attachment D521_1035 87f5dc5e6ac516c4930737a507588a22 433 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 2 432 1.3E-180 T 14-10-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 D521_1035 87f5dc5e6ac516c4930737a507588a22 433 Pfam PF02817 e3 binding domain 132 166 8.0E-15 T 14-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 D521_1035 87f5dc5e6ac516c4930737a507588a22 433 SUPERFAMILY SSF52777 195 430 2.89E-81 T 14-10-2018 D521_1035 87f5dc5e6ac516c4930737a507588a22 433 SUPERFAMILY SSF51230 3 96 1.57E-23 T 14-10-2018 IPR011053 Single hybrid motif D521_1035 87f5dc5e6ac516c4930737a507588a22 433 Gene3D G3DSA:3.30.559.10 191 432 2.7E-90 T 14-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 D521_1035 87f5dc5e6ac516c4930737a507588a22 433 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 D521_1035 87f5dc5e6ac516c4930737a507588a22 433 Gene3D G3DSA:4.10.320.10 132 174 2.5E-19 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 D521_1035 87f5dc5e6ac516c4930737a507588a22 433 SUPERFAMILY SSF47005 128 170 1.18E-12 T 14-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 D521_0269 ebc1ec0e28a905bbebef8b81718a6157 196 SUPERFAMILY SSF54523 23 116 1.1E-7 T 14-10-2018 D521_0269 ebc1ec0e28a905bbebef8b81718a6157 196 Pfam PF12019 Type II transport protein GspH 58 181 9.6E-7 T 14-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 D521_0988 01b58b9b4702dc9b940ceacb668189cf 369 Gene3D G3DSA:3.40.50.300 14 245 1.0E-61 T 14-10-2018 D521_0988 01b58b9b4702dc9b940ceacb668189cf 369 SMART SM00382 22 216 4.6E-17 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0988 01b58b9b4702dc9b940ceacb668189cf 369 SUPERFAMILY SSF52540 14 245 1.49E-69 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0988 01b58b9b4702dc9b940ceacb668189cf 369 SUPERFAMILY SSF50331 242 355 4.93E-5 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal D521_0988 01b58b9b4702dc9b940ceacb668189cf 369 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0988 01b58b9b4702dc9b940ceacb668189cf 369 Pfam PF00005 ABC transporter 15 165 1.6E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0234 75eec16d8f1c0b92f48edc0bb7631cf1 267 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 264 1.2E-94 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0234 75eec16d8f1c0b92f48edc0bb7631cf1 267 Gene3D G3DSA:3.30.360.10 126 233 1.2E-101 T 14-10-2018 D521_0234 75eec16d8f1c0b92f48edc0bb7631cf1 267 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 264 35.27 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0234 75eec16d8f1c0b92f48edc0bb7631cf1 267 PIRSF PIRSF000161 1 267 3.4E-88 T 14-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0234 75eec16d8f1c0b92f48edc0bb7631cf1 267 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 127 263 2.0E-44 T 14-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0234 75eec16d8f1c0b92f48edc0bb7631cf1 267 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 124 3.6E-37 T 14-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0234 75eec16d8f1c0b92f48edc0bb7631cf1 267 SUPERFAMILY SSF51735 1 265 1.29E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0234 75eec16d8f1c0b92f48edc0bb7631cf1 267 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 149 166 - T 14-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 D521_0234 75eec16d8f1c0b92f48edc0bb7631cf1 267 Gene3D G3DSA:3.40.50.720 3 262 1.2E-101 T 14-10-2018 D521_0234 75eec16d8f1c0b92f48edc0bb7631cf1 267 SUPERFAMILY SSF55347 126 235 6.1E-39 T 14-10-2018 D521_0601 7ff1895258fc351e738e0b607c0c048d 358 SUPERFAMILY SSF161098 118 334 1.1E-15 T 14-10-2018 IPR035906 MetI-like superfamily D521_0601 7ff1895258fc351e738e0b607c0c048d 358 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 143 350 1.4E-37 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 D521_0601 7ff1895258fc351e738e0b607c0c048d 358 Gene3D G3DSA:1.10.3720.10 113 343 8.7E-22 T 14-10-2018 IPR035906 MetI-like superfamily D521_0360 a66d3ae7757f1a09d80ac415e5a61a06 275 Pfam PF02424 ApbE family 9 255 8.6E-39 T 14-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 D521_0360 a66d3ae7757f1a09d80ac415e5a61a06 275 SUPERFAMILY SSF143631 4 253 1.65E-50 T 14-10-2018 IPR003374 ApbE-like superfamily D521_0360 a66d3ae7757f1a09d80ac415e5a61a06 275 Gene3D G3DSA:3.10.520.20 2 264 6.3E-46 T 14-10-2018 D521_1163 0fe58fee42ce94d2257850783cad30a6 197 PIRSF PIRSF032086 7 197 5.6E-56 T 14-10-2018 IPR016988 Uncharacterised conserved protein UCP032086 D521_1163 0fe58fee42ce94d2257850783cad30a6 197 Pfam PF06181 Urate oxidase N-terminal 109 191 2.7E-10 T 14-10-2018 IPR010389 Urate oxidase N-terminal D521_1738 7e8922554ec7f5679e8d52dc7c90da7f 88 SUPERFAMILY SSF46992 3 86 6.41E-26 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1738 7e8922554ec7f5679e8d52dc7c90da7f 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.31 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1738 7e8922554ec7f5679e8d52dc7c90da7f 88 Pfam PF01649 Ribosomal protein S20 2 84 8.8E-24 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1738 7e8922554ec7f5679e8d52dc7c90da7f 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 18 88 7.0E-14 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1738 7e8922554ec7f5679e8d52dc7c90da7f 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 1.9E-24 T 14-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1738 7e8922554ec7f5679e8d52dc7c90da7f 88 Gene3D G3DSA:1.20.58.110 1 87 1.6E-25 T 14-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0429 657c29f5aac1b767300dc1626793e198 224 Gene3D G3DSA:3.40.1050.10 1 199 6.3E-61 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 D521_0429 657c29f5aac1b767300dc1626793e198 224 SUPERFAMILY SSF53056 3 200 1.57E-56 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 D521_0429 657c29f5aac1b767300dc1626793e198 224 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 41 48 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 D521_0429 657c29f5aac1b767300dc1626793e198 224 Pfam PF00484 Carbonic anhydrase 36 187 2.8E-47 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 D521_0429 657c29f5aac1b767300dc1626793e198 224 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 86 106 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 D521_0429 657c29f5aac1b767300dc1626793e198 224 SMART SM00947 29 191 1.1E-57 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 D521_1960 7cc8ea16ecf9e5c90ff4b4c44a38ba27 214 SUPERFAMILY SSF55681 2 210 2.4E-59 T 14-10-2018 D521_1960 7cc8ea16ecf9e5c90ff4b4c44a38ba27 214 Hamap MF_00013 Octanoyltransferase [lipB]. 2 214 35.574 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 D521_1960 7cc8ea16ecf9e5c90ff4b4c44a38ba27 214 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 69 84 - T 14-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 D521_1960 7cc8ea16ecf9e5c90ff4b4c44a38ba27 214 Gene3D G3DSA:3.30.930.10 1 211 2.7E-60 T 14-10-2018 D521_1960 7cc8ea16ecf9e5c90ff4b4c44a38ba27 214 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 73 126 4.0E-14 T 14-10-2018 D521_1960 7cc8ea16ecf9e5c90ff4b4c44a38ba27 214 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 24 209 5.1E-53 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 D521_1960 7cc8ea16ecf9e5c90ff4b4c44a38ba27 214 Pfam PF03099 Biotin/lipoate A/B protein ligase family 59 167 7.8E-6 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 D521_1960 7cc8ea16ecf9e5c90ff4b4c44a38ba27 214 PIRSF PIRSF016262 2 213 4.1E-55 T 14-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 D521_0636 fffbd1076f6d395c839926cfeb3f759e 158 Pfam PF07811 TadE-like protein 25 67 2.4E-14 T 14-10-2018 IPR012495 TadE-like D521_0670 2a85b3ae388dbfa784921b83b953585c 449 SUPERFAMILY SSF53383 7 444 2.06E-115 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0670 2a85b3ae388dbfa784921b83b953585c 449 Pfam PF00202 Aminotransferase class-III 31 442 1.8E-90 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_0670 2a85b3ae388dbfa784921b83b953585c 449 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 254 291 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_0670 2a85b3ae388dbfa784921b83b953585c 449 Gene3D G3DSA:3.90.1150.10 28 437 9.7E-142 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_0670 2a85b3ae388dbfa784921b83b953585c 449 PIRSF PIRSF000521 199 445 1.2E-21 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_0670 2a85b3ae388dbfa784921b83b953585c 449 PIRSF PIRSF000521 26 147 4.3E-9 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_0670 2a85b3ae388dbfa784921b83b953585c 449 Gene3D G3DSA:3.40.640.10 65 348 9.7E-142 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 75 225 1.2E-24 T 14-10-2018 D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 106 122 8.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 177 8.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 8.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 209 8.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 8.5E-23 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 Gene3D G3DSA:3.40.50.720 2 226 6.1E-37 T 14-10-2018 D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 112 120 6.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 17 28 6.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 6.5E-5 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0321 9ff469e1723abcc7804cecdc41d7b189 227 SUPERFAMILY SSF51735 6 226 7.76E-40 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1073 aea501ef3fa19cb8d8c010556199b843 384 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 9 383 33.362 T 14-10-2018 IPR017687 Outer membrane protein assembly factor BamB D521_1073 aea501ef3fa19cb8d8c010556199b843 384 Pfam PF13360 PQQ-like domain 81 309 1.1E-47 T 14-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat D521_1073 aea501ef3fa19cb8d8c010556199b843 384 SUPERFAMILY SSF50998 34 374 2.88E-69 T 14-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily D521_1073 aea501ef3fa19cb8d8c010556199b843 384 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 14 381 3.1E-116 T 14-10-2018 IPR017687 Outer membrane protein assembly factor BamB D521_1073 aea501ef3fa19cb8d8c010556199b843 384 Gene3D G3DSA:2.130.10.10 23 383 1.0E-82 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 D521_1073 aea501ef3fa19cb8d8c010556199b843 384 SMART SM00564 321 352 0.0071 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat D521_1073 aea501ef3fa19cb8d8c010556199b843 384 SMART SM00564 191 222 480.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat D521_1073 aea501ef3fa19cb8d8c010556199b843 384 SMART SM00564 145 176 2.2 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat D521_1073 aea501ef3fa19cb8d8c010556199b843 384 SMART SM00564 280 311 200.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat D521_1073 aea501ef3fa19cb8d8c010556199b843 384 SMART SM00564 66 97 4.0E-5 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat D521_1073 aea501ef3fa19cb8d8c010556199b843 384 SMART SM00564 105 136 130.0 T 14-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat D521_1952 b4abbc293671129a0d183c56ce40a96f 313 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 123 296 5.2E-68 T 14-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 D521_1952 b4abbc293671129a0d183c56ce40a96f 313 Hamap MF_00162 Glutathione synthetase [gshB]. 1 313 142.439 T 14-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 D521_1952 b4abbc293671129a0d183c56ce40a96f 313 Gene3D G3DSA:3.30.1490.20 136 200 1.8E-102 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 D521_1952 b4abbc293671129a0d183c56ce40a96f 313 SUPERFAMILY SSF52440 1 121 8.06E-38 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily D521_1952 b4abbc293671129a0d183c56ce40a96f 313 Gene3D G3DSA:3.30.470.20 114 294 1.8E-102 T 14-10-2018 D521_1952 b4abbc293671129a0d183c56ce40a96f 313 TIGRFAM TIGR01380 glut_syn: glutathione synthase 1 311 1.9E-114 T 14-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 D521_1952 b4abbc293671129a0d183c56ce40a96f 313 SUPERFAMILY SSF56059 123 310 6.65E-53 T 14-10-2018 D521_1952 b4abbc293671129a0d183c56ce40a96f 313 Gene3D G3DSA:3.40.50.20 6 113 1.8E-102 T 14-10-2018 D521_1952 b4abbc293671129a0d183c56ce40a96f 313 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 1 119 1.4E-39 T 14-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 D521_0767 b180811c739009a653703f3166a909c7 373 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 15 337 7.0E-61 T 14-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 D521_0767 b180811c739009a653703f3166a909c7 373 Gene3D G3DSA:3.20.20.70 1 356 9.4E-109 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0767 b180811c739009a653703f3166a909c7 373 SUPERFAMILY SSF51395 1 357 1.16E-101 T 14-10-2018 D521_1767 9465d5a9b534eef4cc20174163413fea 286 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 175 279 2.3E-31 T 14-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 D521_1767 9465d5a9b534eef4cc20174163413fea 286 Gene3D G3DSA:3.40.50.720 2 176 3.2E-44 T 14-10-2018 D521_1767 9465d5a9b534eef4cc20174163413fea 286 Gene3D G3DSA:1.10.3730.10 177 283 2.9E-36 T 14-10-2018 D521_1767 9465d5a9b534eef4cc20174163413fea 286 PIRSF PIRSF000193 9 282 1.8E-67 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 D521_1767 9465d5a9b534eef4cc20174163413fea 286 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 235 257 - T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 D521_1767 9465d5a9b534eef4cc20174163413fea 286 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 12 278 2.1E-76 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 D521_1767 9465d5a9b534eef4cc20174163413fea 286 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 10 279 25.11 T 14-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 D521_1767 9465d5a9b534eef4cc20174163413fea 286 SUPERFAMILY SSF48179 174 282 1.26E-31 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_1767 9465d5a9b534eef4cc20174163413fea 286 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 12 112 8.2E-14 T 14-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal D521_1767 9465d5a9b534eef4cc20174163413fea 286 SUPERFAMILY SSF51735 12 172 1.01E-27 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1573 a80d56c6daa98a5fcf3edcbb904e1cb0 215 Pfam PF00535 Glycosyl transferase family 2 3 154 6.1E-13 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 D521_1573 a80d56c6daa98a5fcf3edcbb904e1cb0 215 Gene3D G3DSA:3.90.550.10 1 215 4.2E-22 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1573 a80d56c6daa98a5fcf3edcbb904e1cb0 215 SUPERFAMILY SSF53448 1 202 3.26E-27 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1348 a4c244b4673db7116aa2a27f5d379bb3 152 Gene3D G3DSA:1.20.1280.20 65 152 3.5E-19 T 14-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_1348 a4c244b4673db7116aa2a27f5d379bb3 152 Pfam PF07743 HSCB C-terminal oligomerisation domain 71 144 2.5E-16 T 14-10-2018 IPR009073 Co-chaperone HscB, C-terminal oligomerisation domain GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_1348 a4c244b4673db7116aa2a27f5d379bb3 152 Gene3D G3DSA:1.10.287.110 1 63 4.0E-14 T 14-10-2018 IPR036869 Chaperone J-domain superfamily D521_1348 a4c244b4673db7116aa2a27f5d379bb3 152 TIGRFAM TIGR00714 hscB: Fe-S protein assembly co-chaperone HscB 2 148 1.2E-26 T 14-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_1348 a4c244b4673db7116aa2a27f5d379bb3 152 Hamap MF_00682 Co-chaperone protein HscB [hscB]. 1 152 15.966 T 14-10-2018 IPR004640 Co-chaperone Hsc20 GO:0001671|GO:0051087|GO:0097428 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_1348 a4c244b4673db7116aa2a27f5d379bb3 152 SUPERFAMILY SSF47144 62 151 4.05E-19 T 14-10-2018 IPR036386 HscB, C-terminal domain superfamily GO:0051259 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_1348 a4c244b4673db7116aa2a27f5d379bb3 152 SUPERFAMILY SSF46565 3 59 1.7E-11 T 14-10-2018 IPR036869 Chaperone J-domain superfamily D521_0558 c50d73e082c6dee7e4447f137ff24c19 356 SMART SM00382 38 223 4.9E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0558 c50d73e082c6dee7e4447f137ff24c19 356 Gene3D G3DSA:2.40.50.940 234 355 1.9E-9 T 14-10-2018 D521_0558 c50d73e082c6dee7e4447f137ff24c19 356 SUPERFAMILY SSF50331 252 354 2.65E-11 T 14-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal D521_0558 c50d73e082c6dee7e4447f137ff24c19 356 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0558 c50d73e082c6dee7e4447f137ff24c19 356 SUPERFAMILY SSF52540 8 248 1.6E-76 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0558 c50d73e082c6dee7e4447f137ff24c19 356 Pfam PF00005 ABC transporter 29 173 3.9E-33 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0558 c50d73e082c6dee7e4447f137ff24c19 356 Gene3D G3DSA:2.40.50.140 292 346 1.9E-9 T 14-10-2018 D521_0558 c50d73e082c6dee7e4447f137ff24c19 356 Gene3D G3DSA:3.40.50.300 7 233 3.1E-59 T 14-10-2018 D521_0558 c50d73e082c6dee7e4447f137ff24c19 356 Pfam PF08402 TOBE domain 285 354 2.0E-9 T 14-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 D521_1430 1424a860bc436534a1e0f6c234d4f5dd 336 Gene3D G3DSA:3.40.718.10 1 336 1.1E-125 T 14-10-2018 D521_1430 1424a860bc436534a1e0f6c234d4f5dd 336 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 336 151.867 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 D521_1430 1424a860bc436534a1e0f6c234d4f5dd 336 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 5 331 6.0E-113 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 D521_1430 1424a860bc436534a1e0f6c234d4f5dd 336 Pfam PF02504 Fatty acid synthesis protein 3 325 5.7E-106 T 14-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 D521_1430 1424a860bc436534a1e0f6c234d4f5dd 336 PIRSF PIRSF002465 1 336 1.3E-128 T 14-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 D521_1430 1424a860bc436534a1e0f6c234d4f5dd 336 SUPERFAMILY SSF53659 3 331 1.4E-102 T 14-10-2018 D521_1510 baff2456b4513e60dcd269a96e1837a5 313 Gene3D G3DSA:1.10.1040.10 186 308 1.0E-32 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 D521_1510 baff2456b4513e60dcd269a96e1837a5 313 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 184 282 7.7E-18 T 14-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 D521_1510 baff2456b4513e60dcd269a96e1837a5 313 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 181 2.9E-41 T 14-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 D521_1510 baff2456b4513e60dcd269a96e1837a5 313 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 181 205 - T 14-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 D521_1510 baff2456b4513e60dcd269a96e1837a5 313 Gene3D G3DSA:3.40.50.720 3 184 2.1E-48 T 14-10-2018 D521_1510 baff2456b4513e60dcd269a96e1837a5 313 SUPERFAMILY SSF51735 8 180 3.43E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1510 baff2456b4513e60dcd269a96e1837a5 313 SUPERFAMILY SSF48179 183 289 2.3E-20 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_1510 baff2456b4513e60dcd269a96e1837a5 313 PIRSF PIRSF000105 4 311 7.7E-73 T 14-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 D521_0427 a64ef6a75a76143f9110ed16e5a0d2c7 225 Gene3D G3DSA:1.20.120.700 8 71 1.4E-17 T 14-10-2018 D521_0427 a64ef6a75a76143f9110ed16e5a0d2c7 225 Gene3D G3DSA:1.10.4070.10 72 143 1.4E-17 T 14-10-2018 D521_0427 a64ef6a75a76143f9110ed16e5a0d2c7 225 Pfam PF02613 Nitrate reductase delta subunit 41 133 7.7E-14 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone D521_0427 a64ef6a75a76143f9110ed16e5a0d2c7 225 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 11 163 1.0E-34 T 14-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 D521_0427 a64ef6a75a76143f9110ed16e5a0d2c7 225 SUPERFAMILY SSF89155 7 167 7.72E-33 T 14-10-2018 IPR036411 TorD-like superfamily D521_0611 678f992da94131e2fe932400e582834f 928 Gene3D G3DSA:3.30.56.50 2 50 2.6E-7 T 14-10-2018 D521_0611 678f992da94131e2fe932400e582834f 928 SUPERFAMILY SSF50447 830 926 4.16E-33 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily D521_0611 678f992da94131e2fe932400e582834f 928 Gene3D G3DSA:2.40.30.10 598 716 8.2E-40 T 14-10-2018 D521_0611 678f992da94131e2fe932400e582834f 928 SUPERFAMILY SSF52156 711 835 5.89E-37 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily D521_0611 678f992da94131e2fe932400e582834f 928 Gene3D G3DSA:3.40.50.10050 723 829 5.6E-38 T 14-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily D521_0611 678f992da94131e2fe932400e582834f 928 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 61 98 8.8E-13 T 14-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial D521_0611 678f992da94131e2fe932400e582834f 928 SUPERFAMILY SSF46955 3 50 2.2E-9 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily D521_0611 678f992da94131e2fe932400e582834f 928 Pfam PF00009 Elongation factor Tu GTP binding domain 431 586 7.6E-35 T 14-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 D521_0611 678f992da94131e2fe932400e582834f 928 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 346 928 4.0E-253 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 D521_0611 678f992da94131e2fe932400e582834f 928 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 926 17.292 T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 D521_0611 678f992da94131e2fe932400e582834f 928 ProSitePatterns PS01176 Initiation factor 2 signature. 879 901 - T 14-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 D521_0611 678f992da94131e2fe932400e582834f 928 SUPERFAMILY SSF50447 599 681 6.45E-26 T 14-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily D521_0611 678f992da94131e2fe932400e582834f 928 Pfam PF11987 Translation-initiation factor 2 712 818 7.4E-37 T 14-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 D521_0611 678f992da94131e2fe932400e582834f 928 SUPERFAMILY SSF52540 423 597 3.0E-52 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0611 678f992da94131e2fe932400e582834f 928 Gene3D G3DSA:2.40.30.10 830 927 4.3E-32 T 14-10-2018 D521_0611 678f992da94131e2fe932400e582834f 928 Gene3D G3DSA:3.40.50.300 423 597 1.1E-69 T 14-10-2018 D521_0611 678f992da94131e2fe932400e582834f 928 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 429 585 1.2E-31 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 D521_0611 678f992da94131e2fe932400e582834f 928 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 351 401 1.1E-14 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal D521_0611 678f992da94131e2fe932400e582834f 928 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 3 51 1.9E-7 T 14-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal D521_2076 2d0ba879fb82b4a2c70db28f3ec0e536 181 Gene3D G3DSA:3.40.50.1820 13 176 6.4E-11 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_2076 2d0ba879fb82b4a2c70db28f3ec0e536 181 SUPERFAMILY SSF53474 26 171 4.16E-12 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_2076 2d0ba879fb82b4a2c70db28f3ec0e536 181 Pfam PF06028 Alpha/beta hydrolase of unknown function (DUF915) 27 64 1.6E-5 T 14-10-2018 IPR010315 Protein of unknown function DUF915, hydrolase-like D521_1231 b2b1b069a36434825e49f3b4eaea193c 265 SMART SM00460 155 220 2.1E-10 T 14-10-2018 IPR002931 Transglutaminase-like D521_1231 b2b1b069a36434825e49f3b4eaea193c 265 Pfam PF01841 Transglutaminase-like superfamily 121 217 1.9E-17 T 14-10-2018 IPR002931 Transglutaminase-like D521_1231 b2b1b069a36434825e49f3b4eaea193c 265 SUPERFAMILY SSF54001 7 246 6.87E-33 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily D521_1231 b2b1b069a36434825e49f3b4eaea193c 265 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 3 78 3.0E-18 T 14-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal D521_1231 b2b1b069a36434825e49f3b4eaea193c 265 Gene3D G3DSA:3.10.620.30 37 250 3.5E-42 T 14-10-2018 D521_0921 82c1cf2faf6f56e4f5d3269780fddd54 186 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 12 117 3.8E-46 T 14-10-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 D521_0921 82c1cf2faf6f56e4f5d3269780fddd54 186 Pfam PF05233 PHB accumulation regulatory domain 77 115 2.1E-17 T 14-10-2018 IPR007897 PHB accumulation regulatory D521_0921 82c1cf2faf6f56e4f5d3269780fddd54 186 Pfam PF05233 PHB accumulation regulatory domain 127 165 1.4E-15 T 14-10-2018 IPR007897 PHB accumulation regulatory D521_0921 82c1cf2faf6f56e4f5d3269780fddd54 186 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 13 72 5.2E-30 T 14-10-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 1.9E-43 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 1.9E-43 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 1.9E-43 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 1.9E-43 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 1.9E-43 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 1.9E-43 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 148 7.4E-65 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 SUPERFAMILY SSF52096 5 316 1.99E-101 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 2 318 1.4E-143 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 Gene3D G3DSA:3.90.226.10 1 318 2.6E-121 T 14-10-2018 D521_0866 8c4ea7ae7037cba29cf0166952ea18e8 323 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 48.451 T 14-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_1943 a7ede9f5e873b1a4bfc4d3d574c847bd 173 Gene3D G3DSA:3.10.420.10 1 169 4.3E-52 T 14-10-2018 IPR035958 SecB-like superfamily D521_1943 a7ede9f5e873b1a4bfc4d3d574c847bd 173 Pfam PF02556 Preprotein translocase subunit SecB 14 152 3.6E-51 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 D521_1943 a7ede9f5e873b1a4bfc4d3d574c847bd 173 SUPERFAMILY SSF54611 13 149 9.81E-48 T 14-10-2018 IPR035958 SecB-like superfamily D521_1943 a7ede9f5e873b1a4bfc4d3d574c847bd 173 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 16 149 6.1E-46 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 D521_1943 a7ede9f5e873b1a4bfc4d3d574c847bd 173 Hamap MF_00821 Protein-export protein SecB [secB]. 1 154 30.888 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 D521_1943 a7ede9f5e873b1a4bfc4d3d574c847bd 173 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 82 102 3.4E-27 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 D521_1943 a7ede9f5e873b1a4bfc4d3d574c847bd 173 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 22 39 3.4E-27 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 D521_1943 a7ede9f5e873b1a4bfc4d3d574c847bd 173 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 106 128 3.4E-27 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 D521_1943 a7ede9f5e873b1a4bfc4d3d574c847bd 173 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 132 150 3.4E-27 T 14-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 D521_0871 b321e693a58b54317c7d37b2e0183ad6 147 Gene3D G3DSA:3.30.1370.110 40 147 6.3E-6 T 14-10-2018 D521_0871 b321e693a58b54317c7d37b2e0183ad6 147 SUPERFAMILY SSF160443 47 97 8.63E-5 T 14-10-2018 IPR036063 Smr domain superfamily D521_0871 b321e693a58b54317c7d37b2e0183ad6 147 Pfam PF01713 Smr domain 47 110 1.4E-5 T 14-10-2018 IPR002625 Smr domain D521_1447 ff0be0990780d2b06c16c8f9c1b29c7c 165 SUPERFAMILY SSF53597 3 164 1.44E-56 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 D521_1447 ff0be0990780d2b06c16c8f9c1b29c7c 165 Pfam PF00186 Dihydrofolate reductase 9 164 6.8E-58 T 14-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 D521_1447 ff0be0990780d2b06c16c8f9c1b29c7c 165 Gene3D G3DSA:3.40.430.10 8 165 1.4E-60 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 D521_1447 ff0be0990780d2b06c16c8f9c1b29c7c 165 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 20 42 - T 14-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 D521_1447 ff0be0990780d2b06c16c8f9c1b29c7c 165 PIRSF PIRSF000194 4 165 6.7E-59 T 14-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 D521_1447 ff0be0990780d2b06c16c8f9c1b29c7c 165 PRINTS PR00070 Dihydrofolate reductase signature 20 30 5.1E-16 T 14-10-2018 D521_1447 ff0be0990780d2b06c16c8f9c1b29c7c 165 PRINTS PR00070 Dihydrofolate reductase signature 34 42 5.1E-16 T 14-10-2018 D521_1447 ff0be0990780d2b06c16c8f9c1b29c7c 165 PRINTS PR00070 Dihydrofolate reductase signature 47 58 5.1E-16 T 14-10-2018 D521_1447 ff0be0990780d2b06c16c8f9c1b29c7c 165 PRINTS PR00070 Dihydrofolate reductase signature 98 112 5.1E-16 T 14-10-2018 D521_0959 1fd143e0c1c38c0e5471eeb77f802a25 161 SUPERFAMILY SSF54637 18 141 1.27E-27 T 14-10-2018 IPR029069 HotDog domain superfamily D521_0959 1fd143e0c1c38c0e5471eeb77f802a25 161 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 24 136 5.0E-19 T 14-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 D521_0959 1fd143e0c1c38c0e5471eeb77f802a25 161 Gene3D G3DSA:3.10.129.10 14 149 1.9E-36 T 14-10-2018 D521_0959 1fd143e0c1c38c0e5471eeb77f802a25 161 Pfam PF03061 Thioesterase superfamily 56 130 1.5E-11 T 14-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 D521_0509 2c2233f7a9ca8096fa619d60abb6c84a 415 Gene3D G3DSA:3.30.1540.10 242 338 1.0E-156 T 14-10-2018 D521_0509 2c2233f7a9ca8096fa619d60abb6c84a 415 Pfam PF02515 CoA-transferase family III 5 392 1.6E-99 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 D521_0509 2c2233f7a9ca8096fa619d60abb6c84a 415 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 3 415 8.6E-222 T 14-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 D521_0509 2c2233f7a9ca8096fa619d60abb6c84a 415 Gene3D G3DSA:3.40.50.10540 5 406 1.0E-156 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_0509 2c2233f7a9ca8096fa619d60abb6c84a 415 SUPERFAMILY SSF89796 1 415 3.27E-123 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_0509 2c2233f7a9ca8096fa619d60abb6c84a 415 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 1 415 64.963 T 14-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 D521_1953 6f19079299f59434a3bba81081a948c0 432 Gene3D G3DSA:3.40.50.11280 65 207 3.0E-47 T 14-10-2018 D521_1953 6f19079299f59434a3bba81081a948c0 432 TIGRFAM TIGR02049 gshA_ferroox: glutamate--cysteine ligase 17 424 4.0E-198 T 14-10-2018 IPR011718 Glutamate--cysteine ligase GshA D521_1953 6f19079299f59434a3bba81081a948c0 432 SUPERFAMILY SSF56059 279 359 7.28E-5 T 14-10-2018 D521_1953 6f19079299f59434a3bba81081a948c0 432 Pfam PF08886 Glutamate-cysteine ligase 17 422 2.2E-199 T 14-10-2018 IPR011718 Glutamate--cysteine ligase GshA D521_0091 b696ee0bb3526104da2518966dd0b0b6 729 Pfam PF17092 Penicillin-binding protein OB-like domain 304 407 1.5E-19 T 14-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0091 b696ee0bb3526104da2518966dd0b0b6 729 Pfam PF00905 Penicillin binding protein transpeptidase domain 410 660 1.0E-42 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 D521_0091 b696ee0bb3526104da2518966dd0b0b6 729 SUPERFAMILY SSF53955 31 239 9.84E-74 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily D521_0091 b696ee0bb3526104da2518966dd0b0b6 729 Pfam PF00912 Transglycosylase 45 217 2.1E-62 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0091 b696ee0bb3526104da2518966dd0b0b6 729 Gene3D G3DSA:2.40.50.140 335 405 1.7E-18 T 14-10-2018 D521_0091 b696ee0bb3526104da2518966dd0b0b6 729 Gene3D G3DSA:1.10.3810.10 38 232 5.6E-74 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0091 b696ee0bb3526104da2518966dd0b0b6 729 SUPERFAMILY SSF56601 199 719 5.83E-120 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like D521_0091 b696ee0bb3526104da2518966dd0b0b6 729 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 54 694 4.1E-188 T 14-10-2018 D521_0620 b44d9a641439fff9edb7a52d71e3948f 159 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 6 136 1.4E-10 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I D521_0620 b44d9a641439fff9edb7a52d71e3948f 159 Gene3D G3DSA:3.40.50.2300 1 142 2.3E-34 T 14-10-2018 D521_0620 b44d9a641439fff9edb7a52d71e3948f 159 SUPERFAMILY SSF52788 4 141 1.44E-32 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily D521_0620 b44d9a641439fff9edb7a52d71e3948f 159 SMART SM00226 4 142 4.5E-19 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I D521_1559 dd212856c5531644592b9ddb8d48caa9 279 Pfam PF00850 Histone deacetylase domain 6 257 1.6E-51 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 D521_1559 dd212856c5531644592b9ddb8d48caa9 279 PRINTS PR01270 Histone deacetylase superfamily signature 200 210 2.4E-14 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 D521_1559 dd212856c5531644592b9ddb8d48caa9 279 PRINTS PR01270 Histone deacetylase superfamily signature 92 115 2.4E-14 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 D521_1559 dd212856c5531644592b9ddb8d48caa9 279 PRINTS PR01270 Histone deacetylase superfamily signature 127 142 2.4E-14 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 D521_1559 dd212856c5531644592b9ddb8d48caa9 279 SUPERFAMILY SSF52768 3 258 6.23E-73 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily D521_1559 dd212856c5531644592b9ddb8d48caa9 279 Gene3D G3DSA:3.40.800.20 1 278 4.6E-66 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 D521_1409 65fa2bb7f82c2fa66c6431cac2849643 308 Gene3D G3DSA:2.40.30.170 60 255 1.9E-12 T 14-10-2018 D521_1409 65fa2bb7f82c2fa66c6431cac2849643 308 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 76 246 9.7E-10 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain D521_1409 65fa2bb7f82c2fa66c6431cac2849643 308 Gene3D G3DSA:2.40.50.100 69 215 1.9E-12 T 14-10-2018 D521_1409 65fa2bb7f82c2fa66c6431cac2849643 308 Gene3D G3DSA:1.10.287.470 103 181 1.9E-12 T 14-10-2018 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 PIRSF PIRSF001438 2 323 2.6E-112 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 245 261 - T 14-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 240 312 4.0E-14 T 14-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 SUPERFAMILY SSF54782 234 321 3.4E-21 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 Gene3D G3DSA:3.30.160.40 236 322 7.1E-22 T 14-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 20 314 1.2E-102 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 Gene3D G3DSA:3.40.190.10 21 221 1.0E-78 T 14-10-2018 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 Gene3D G3DSA:3.40.190.10 117 216 1.0E-78 T 14-10-2018 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 PRINTS PR00151 Porphobilinogen deaminase signature 90 109 9.0E-45 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 PRINTS PR00151 Porphobilinogen deaminase signature 244 261 9.0E-45 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 PRINTS PR00151 Porphobilinogen deaminase signature 59 79 9.0E-45 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 PRINTS PR00151 Porphobilinogen deaminase signature 157 174 9.0E-45 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 PRINTS PR00151 Porphobilinogen deaminase signature 138 155 9.0E-45 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 SUPERFAMILY SSF53850 19 233 4.59E-80 T 14-10-2018 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 20 227 1.8E-72 T 14-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0521 a4d60dc768bb4f38b52768010a47c970 326 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 19 314 36.052 T 14-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0173 6ded1ee1d8164a7fae364eee6198d60b 288 Pfam PF08478 POTRA domain, FtsQ-type 73 131 1.2E-11 T 14-10-2018 IPR013685 POTRA domain, FtsQ-type D521_0173 6ded1ee1d8164a7fae364eee6198d60b 288 Gene3D G3DSA:3.10.20.310 59 131 2.1E-14 T 14-10-2018 D521_0173 6ded1ee1d8164a7fae364eee6198d60b 288 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 28 268 18.729 T 14-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 D521_0173 6ded1ee1d8164a7fae364eee6198d60b 288 Pfam PF03799 Cell division protein FtsQ 142 260 1.5E-22 T 14-10-2018 IPR005548 Cell division protein FtsQ/DivIB D521_0173 6ded1ee1d8164a7fae364eee6198d60b 288 Gene3D G3DSA:3.40.50.11690 133 274 5.6E-33 T 14-10-2018 D521_2070 8676b37c48315a8162c915103ab24bbb 131 PIRSF PIRSF029720 1 131 1.3E-42 T 14-10-2018 IPR014558 Uncharacterised conserved lipoprotein D521_2070 8676b37c48315a8162c915103ab24bbb 131 Pfam PF03640 Secreted repeat of unknown function 86 130 3.1E-18 T 14-10-2018 IPR005297 Lipoprotein repeat D521_2070 8676b37c48315a8162c915103ab24bbb 131 Pfam PF03640 Secreted repeat of unknown function 34 73 8.9E-14 T 14-10-2018 IPR005297 Lipoprotein repeat D521_0025 672055b8d3ab047f7a715f050407af36 710 TIGRFAM TIGR00595 priA: primosomal protein N' 171 707 4.5E-150 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 D521_0025 672055b8d3ab047f7a715f050407af36 710 SUPERFAMILY SSF52540 143 328 8.71E-36 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0025 672055b8d3ab047f7a715f050407af36 710 SUPERFAMILY SSF52540 429 584 4.04E-19 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0025 672055b8d3ab047f7a715f050407af36 710 Gene3D G3DSA:3.40.50.300 134 331 5.8E-61 T 14-10-2018 D521_0025 672055b8d3ab047f7a715f050407af36 710 SMART SM00490 461 558 4.5E-6 T 14-10-2018 IPR001650 Helicase, C-terminal D521_0025 672055b8d3ab047f7a715f050407af36 710 SMART SM00487 142 344 2.0E-25 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_0025 672055b8d3ab047f7a715f050407af36 710 Pfam PF00270 DEAD/DEAH box helicase 148 312 2.6E-14 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 D521_0025 672055b8d3ab047f7a715f050407af36 710 Gene3D G3DSA:1.10.8.630 6 117 1.7E-22 T 14-10-2018 D521_0025 672055b8d3ab047f7a715f050407af36 710 Hamap MF_00983 Probable primosomal protein N' [priA]. 10 710 21.586 T 14-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 D521_0025 672055b8d3ab047f7a715f050407af36 710 Pfam PF00271 Helicase conserved C-terminal domain 483 558 1.8E-5 T 14-10-2018 IPR001650 Helicase, C-terminal D521_1720 f4cc5e141ea1d0907b379eac0b361bc3 55 SUPERFAMILY SSF57829 1 53 1.28E-18 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 D521_1720 f4cc5e141ea1d0907b379eac0b361bc3 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 14-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1720 f4cc5e141ea1d0907b379eac0b361bc3 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 14.429 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1720 f4cc5e141ea1d0907b379eac0b361bc3 55 Pfam PF00471 Ribosomal protein L33 7 53 2.7E-17 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1720 f4cc5e141ea1d0907b379eac0b361bc3 55 Gene3D G3DSA:2.20.28.120 1 55 8.6E-28 T 14-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1720 f4cc5e141ea1d0907b379eac0b361bc3 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 2.7E-25 T 14-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1542 1316ef319a2098377a0c938724c8486c 221 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 7 217 4.7E-71 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria D521_1542 1316ef319a2098377a0c938724c8486c 221 Pfam PF03379 CcmB protein 5 218 3.4E-72 T 14-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1542 1316ef319a2098377a0c938724c8486c 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 133 156 3.6E-53 T 14-10-2018 D521_1542 1316ef319a2098377a0c938724c8486c 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 77 100 3.6E-53 T 14-10-2018 D521_1542 1316ef319a2098377a0c938724c8486c 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 102 120 3.6E-53 T 14-10-2018 D521_1542 1316ef319a2098377a0c938724c8486c 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 156 175 3.6E-53 T 14-10-2018 D521_1542 1316ef319a2098377a0c938724c8486c 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 194 217 3.6E-53 T 14-10-2018 D521_1542 1316ef319a2098377a0c938724c8486c 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 54 71 3.6E-53 T 14-10-2018 D521_1542 1316ef319a2098377a0c938724c8486c 221 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 28 49 3.6E-53 T 14-10-2018 D521_1542 1316ef319a2098377a0c938724c8486c 221 PIRSF PIRSF002764 1 221 1.4E-77 T 14-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria D521_0210 84119e230df77b5e33559145d56835a3 319 SUPERFAMILY SSF53613 4 306 7.33E-63 T 14-10-2018 IPR029056 Ribokinase-like D521_0210 84119e230df77b5e33559145d56835a3 319 Gene3D G3DSA:3.40.1190.20 1 318 2.0E-106 T 14-10-2018 IPR029056 Ribokinase-like D521_0210 84119e230df77b5e33559145d56835a3 319 Pfam PF00294 pfkB family carbohydrate kinase 34 299 7.3E-41 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB D521_0210 84119e230df77b5e33559145d56835a3 319 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 D521_1391 8e796645b3891dcdb6f1d38d514a4600 348 Gene3D G3DSA:3.40.50.720 3 319 1.7E-117 T 14-10-2018 D521_1391 8e796645b3891dcdb6f1d38d514a4600 348 Gene3D G3DSA:3.90.25.10 194 332 1.7E-117 T 14-10-2018 D521_1391 8e796645b3891dcdb6f1d38d514a4600 348 SUPERFAMILY SSF51735 2 336 5.8E-67 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1391 8e796645b3891dcdb6f1d38d514a4600 348 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 251 1.2E-46 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 D521_2118 4200833c3998cb1f36b06840bec6bf32 88 Gene3D G3DSA:3.30.230.10 3 86 2.2E-15 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup D521_2118 4200833c3998cb1f36b06840bec6bf32 88 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 66 2.0E-7 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 D521_2118 4200833c3998cb1f36b06840bec6bf32 88 Pfam PF00825 Ribonuclease P 5 81 3.5E-14 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 D521_2118 4200833c3998cb1f36b06840bec6bf32 88 SUPERFAMILY SSF54211 5 74 5.06E-13 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_2118 4200833c3998cb1f36b06840bec6bf32 88 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 27 41 - T 14-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 D521_2118 4200833c3998cb1f36b06840bec6bf32 88 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 6 80 5.7E-12 T 14-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 SUPERFAMILY SSF55103 709 812 1.64E-27 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 SUPERFAMILY SSF46548 824 942 2.27E-13 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 Pfam PF13183 4Fe-4S dicluster domain 846 925 6.6E-7 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 Pfam PF11880 Domain of unknown function (DUF3400) 1275 1318 5.7E-22 T 14-10-2018 IPR021817 Protein of unknown function DUF3400 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 Gene3D G3DSA:3.30.70.2740 703 774 6.4E-7 T 14-10-2018 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 Gene3D G3DSA:3.30.465.40 181 376 4.7E-33 T 14-10-2018 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 Pfam PF01565 FAD binding domain 219 366 1.7E-22 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 SUPERFAMILY SSF55103 484 608 2.62E-14 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 Pfam PF02754 Cysteine-rich domain 1056 1145 7.9E-6 T 14-10-2018 IPR004017 Cysteine-rich domain D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 Pfam PF02754 Cysteine-rich domain 1181 1271 1.6E-4 T 14-10-2018 IPR004017 Cysteine-rich domain D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 SUPERFAMILY SSF56176 182 452 4.5E-52 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 Pfam PF12447 Protein of unknown function (DUF3683) 58 171 2.1E-50 T 14-10-2018 IPR022153 Protein of unknown function DUF3683 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 Pfam PF02913 FAD linked oxidases, C-terminal domain 488 603 1.1E-5 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 D521_1894 14e33f0eca00e22b3e5bd3f252098ac3 1318 Pfam PF02913 FAD linked oxidases, C-terminal domain 722 810 2.2E-18 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 D521_0796 391571d72a6e78d1ec272955b8aa1767 336 Gene3D G3DSA:1.20.58.340 281 335 1.6E-8 T 14-10-2018 D521_0796 391571d72a6e78d1ec272955b8aa1767 336 SUPERFAMILY SSF143865 4 269 7.45E-38 T 14-10-2018 D521_0796 391571d72a6e78d1ec272955b8aa1767 336 Gene3D G3DSA:1.20.58.340 150 273 3.9E-17 T 14-10-2018 D521_0796 391571d72a6e78d1ec272955b8aa1767 336 SUPERFAMILY SSF144083 277 333 4.97E-12 T 14-10-2018 D521_0796 391571d72a6e78d1ec272955b8aa1767 336 Pfam PF01544 CorA-like Mg2+ transporter protein 45 333 3.8E-55 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 D521_0796 391571d72a6e78d1ec272955b8aa1767 336 Gene3D G3DSA:3.30.460.20 2 146 1.1E-27 T 14-10-2018 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 SUPERFAMILY SSF53697 11 494 1.68E-157 T 14-10-2018 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 15 470 35.119 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 443 460 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 Pfam PF00342 Phosphoglucose isomerase 25 476 2.6E-148 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 Gene3D G3DSA:3.40.50.10490 67 254 2.0E-164 T 14-10-2018 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 228 241 - T 14-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 Gene3D G3DSA:1.10.1390.10 453 498 1.4E-11 T 14-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 PRINTS PR00662 Glucose-6-phosphate isomerase signature 429 443 1.9E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 PRINTS PR00662 Glucose-6-phosphate isomerase signature 443 456 1.9E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 PRINTS PR00662 Glucose-6-phosphate isomerase signature 224 242 1.9E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 PRINTS PR00662 Glucose-6-phosphate isomerase signature 301 322 1.9E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 PRINTS PR00662 Glucose-6-phosphate isomerase signature 109 128 1.9E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 PRINTS PR00662 Glucose-6-phosphate isomerase signature 411 429 1.9E-47 T 14-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0702 19b744fe31d0357cd2562f9c4a094bbb 498 Gene3D G3DSA:3.40.50.10490 12 452 2.0E-164 T 14-10-2018 D521_1704 369932de6cb6264c64b25618ab4c636b 795 Gene3D G3DSA:3.40.50.300 295 657 1.7E-116 T 14-10-2018 D521_1704 369932de6cb6264c64b25618ab4c636b 795 SUPERFAMILY SSF52540 3 664 1.52E-171 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1704 369932de6cb6264c64b25618ab4c636b 795 Pfam PF13361 UvrD-like helicase C-terminal domain 292 640 1.2E-71 T 14-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 D521_1704 369932de6cb6264c64b25618ab4c636b 795 Gene3D G3DSA:1.10.10.160 120 192 1.3E-87 T 14-10-2018 IPR013986 DExx box DNA helicase domain superfamily D521_1704 369932de6cb6264c64b25618ab4c636b 795 Gene3D G3DSA:1.10.486.10 397 570 1.7E-116 T 14-10-2018 D521_1704 369932de6cb6264c64b25618ab4c636b 795 Gene3D G3DSA:3.40.50.300 9 288 1.3E-87 T 14-10-2018 D521_1704 369932de6cb6264c64b25618ab4c636b 795 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 287 1.3E-70 T 14-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 SMART SM00086 401 443 9.9E-6 T 14-10-2018 IPR001610 PAC motif D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 468 636 2.4E-49 T 14-10-2018 IPR000160 GGDEF domain D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 Gene3D G3DSA:3.30.70.270 457 639 5.8E-58 T 14-10-2018 D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 Pfam PF00990 Diguanylate cyclase, GGDEF domain 471 635 2.1E-47 T 14-10-2018 IPR000160 GGDEF domain D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 Gene3D G3DSA:3.30.450.20 40 135 1.9E-6 T 14-10-2018 D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 SUPERFAMILY SSF55073 476 639 2.82E-46 T 14-10-2018 IPR029787 Nucleotide cyclase D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 Pfam PF13426 PAS domain 345 442 5.9E-11 T 14-10-2018 IPR000014 PAS domain D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 SUPERFAMILY SSF55785 338 440 2.27E-23 T 14-10-2018 IPR035965 PAS domain superfamily D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 Gene3D G3DSA:3.30.450.20 320 455 2.3E-23 T 14-10-2018 D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 SMART SM00267 460 639 2.4E-62 T 14-10-2018 IPR000160 GGDEF domain D521_1833 e1fbcb6c60010ed72f30148663cc4573 641 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 341 449 1.9E-12 T 14-10-2018 IPR000014 PAS domain D521_2025 16d860282c4a3ee33cc2812510735719 174 PIRSF PIRSF018472 7 167 2.7E-32 T 14-10-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type D521_2025 16d860282c4a3ee33cc2812510735719 174 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 14 159 4.0E-24 T 14-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 D521_2025 16d860282c4a3ee33cc2812510735719 174 Pfam PF04093 rod shape-determining protein MreD 16 153 5.0E-14 T 14-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 D521_1428 8b9a2dd9a4f7fc31f24814f28cb5915a 311 Gene3D G3DSA:3.40.366.10 4 284 9.7E-98 T 14-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 D521_1428 8b9a2dd9a4f7fc31f24814f28cb5915a 311 PIRSF PIRSF000446 1 311 8.1E-112 T 14-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 D521_1428 8b9a2dd9a4f7fc31f24814f28cb5915a 311 Pfam PF00698 Acyl transferase domain 5 281 2.7E-33 T 14-10-2018 IPR014043 Acyl transferase D521_1428 8b9a2dd9a4f7fc31f24814f28cb5915a 311 SUPERFAMILY SSF52151 3 307 1.05E-74 T 14-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase D521_1428 8b9a2dd9a4f7fc31f24814f28cb5915a 311 Gene3D G3DSA:3.30.70.250 123 197 9.7E-98 T 14-10-2018 D521_1428 8b9a2dd9a4f7fc31f24814f28cb5915a 311 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 6 305 1.5E-31 T 14-10-2018 IPR020801 Polyketide synthase, acyl transferase domain D521_1428 8b9a2dd9a4f7fc31f24814f28cb5915a 311 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 291 7.0E-106 T 14-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 D521_1428 8b9a2dd9a4f7fc31f24814f28cb5915a 311 SUPERFAMILY SSF55048 126 197 8.37E-16 T 14-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding D521_0888 6b4523a9d45f656c85a6530424ec180b 272 Hamap MF_00443 Thiazole synthase [thiG]. 14 268 40.081 T 14-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 D521_0888 6b4523a9d45f656c85a6530424ec180b 272 Pfam PF05690 Thiazole biosynthesis protein ThiG 17 262 5.7E-105 T 14-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 D521_0888 6b4523a9d45f656c85a6530424ec180b 272 Gene3D G3DSA:3.20.20.70 9 267 1.7E-101 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0888 6b4523a9d45f656c85a6530424ec180b 272 SUPERFAMILY SSF110399 13 252 7.72E-80 T 14-10-2018 D521_1188 e3f9e491b80079665357127d49ca17ad 219 Gene3D G3DSA:3.30.70.20 5 181 4.4E-35 T 14-10-2018 D521_1188 e3f9e491b80079665357127d49ca17ad 219 SUPERFAMILY SSF54862 1 181 8.58E-49 T 14-10-2018 D521_1188 e3f9e491b80079665357127d49ca17ad 219 PRINTS PR00354 7Fe ferredoxin signature 66 76 1.6E-5 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 D521_1188 e3f9e491b80079665357127d49ca17ad 219 PRINTS PR00354 7Fe ferredoxin signature 83 100 1.6E-5 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 D521_1188 e3f9e491b80079665357127d49ca17ad 219 PRINTS PR00354 7Fe ferredoxin signature 56 66 1.6E-5 T 14-10-2018 IPR000813 7Fe ferredoxin GO:0009055 D521_1188 e3f9e491b80079665357127d49ca17ad 219 Gene3D G3DSA:3.30.70.20 62 119 4.4E-35 T 14-10-2018 D521_1188 e3f9e491b80079665357127d49ca17ad 219 Pfam PF13247 4Fe-4S dicluster domain 53 164 1.7E-9 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_1188 e3f9e491b80079665357127d49ca17ad 219 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_0065 497d4485da184b79955c40b65514349d 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 26.794 T 14-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid D521_0065 497d4485da184b79955c40b65514349d 101 Gene3D G3DSA:4.10.830.10 40 101 6.4E-21 T 14-10-2018 D521_0065 497d4485da184b79955c40b65514349d 101 SUPERFAMILY SSF57716 2 101 3.49E-37 T 14-10-2018 D521_0065 497d4485da184b79955c40b65514349d 101 Pfam PF00253 Ribosomal protein S14p/S29e 47 100 2.9E-24 T 14-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_2026 cb151f5ff256177935ce07244194d194 635 SUPERFAMILY SSF56601 262 623 1.73E-99 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like D521_2026 cb151f5ff256177935ce07244194d194 635 Pfam PF00905 Penicillin binding protein transpeptidase domain 278 616 2.1E-73 T 14-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 D521_2026 cb151f5ff256177935ce07244194d194 635 Pfam PF03717 Penicillin-binding Protein dimerisation domain 59 246 5.7E-33 T 14-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 D521_2026 cb151f5ff256177935ce07244194d194 635 SUPERFAMILY SSF56519 51 260 2.88E-38 T 14-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 D521_2026 cb151f5ff256177935ce07244194d194 635 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 15 621 4.7E-216 T 14-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 D521_2026 cb151f5ff256177935ce07244194d194 635 Gene3D G3DSA:3.40.710.10 261 631 3.8E-97 T 14-10-2018 D521_0418 d43f6e979b83d1e53071118c0202bdd7 806 Pfam PF02867 Ribonucleotide reductase, barrel domain 78 574 6.2E-135 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0418 d43f6e979b83d1e53071118c0202bdd7 806 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 10 580 8.9E-171 T 14-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 D521_0418 d43f6e979b83d1e53071118c0202bdd7 806 SUPERFAMILY SSF51998 3 604 2.41E-162 T 14-10-2018 D521_0418 d43f6e979b83d1e53071118c0202bdd7 806 Gene3D G3DSA:3.20.70.20 1 588 9.7E-184 T 14-10-2018 D521_0418 d43f6e979b83d1e53071118c0202bdd7 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 320 343 1.4E-26 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0418 d43f6e979b83d1e53071118c0202bdd7 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 160 179 1.4E-26 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0418 d43f6e979b83d1e53071118c0202bdd7 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 386 409 1.4E-26 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0418 d43f6e979b83d1e53071118c0202bdd7 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 358 380 1.4E-26 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0418 d43f6e979b83d1e53071118c0202bdd7 806 PRINTS PR01183 Ribonucleotide reductase large chain signature 442 469 1.4E-26 T 14-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 7.5E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 7.5E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 7.5E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 7.5E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 7.5E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 7.5E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 244 1.7E-69 T 14-10-2018 D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 Gene3D G3DSA:3.40.50.720 2 246 2.0E-87 T 14-10-2018 D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 10 245 2.6E-101 T 14-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 SUPERFAMILY SSF51735 7 246 1.0E-85 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 5.0E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 5.0E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.0E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1427 64a76b8878b2c08f0e3f3c387617b490 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 189 1.3E-4 T 14-10-2018 D521_1604 54b176b1dd8e0658595cf3798c5f0ae0 388 Pfam PF02515 CoA-transferase family III 12 377 4.0E-128 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 D521_1604 54b176b1dd8e0658595cf3798c5f0ae0 388 SUPERFAMILY SSF89796 10 387 7.46E-127 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_1604 54b176b1dd8e0658595cf3798c5f0ae0 388 Gene3D G3DSA:3.40.50.10540 11 354 3.2E-135 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_1604 54b176b1dd8e0658595cf3798c5f0ae0 388 Gene3D G3DSA:3.30.1540.10 232 323 3.2E-135 T 14-10-2018 D521_1859 6f74e94097c6554a767dcdb101d1cbf3 190 SUPERFAMILY SSF56784 5 185 1.18E-39 T 14-10-2018 IPR036412 HAD-like superfamily D521_1859 6f74e94097c6554a767dcdb101d1cbf3 190 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 7 151 6.8E-33 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 D521_1859 6f74e94097c6554a767dcdb101d1cbf3 190 PIRSF PIRSF004682 1 189 4.3E-49 T 14-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 D521_1859 6f74e94097c6554a767dcdb101d1cbf3 190 Gene3D G3DSA:3.40.50.1000 6 190 1.5E-48 T 14-10-2018 IPR023214 HAD superfamily D521_1859 6f74e94097c6554a767dcdb101d1cbf3 190 Pfam PF08645 Polynucleotide kinase 3 phosphatase 22 124 1.5E-9 T 14-10-2018 IPR013954 Polynucleotide kinase 3 phosphatase Reactome: R-HSA-5649702 D521_1859 6f74e94097c6554a767dcdb101d1cbf3 190 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 8 152 2.8E-41 T 14-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 SUPERFAMILY SSF56645 13 242 3.27E-66 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 Gene3D G3DSA:2.40.110.10 120 230 1.1E-112 T 14-10-2018 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 Gene3D G3DSA:1.20.140.10 231 378 1.1E-112 T 14-10-2018 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 117 3.2E-21 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 Gene3D G3DSA:1.10.540.10 15 119 1.1E-112 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 14-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 SUPERFAMILY SSF47203 229 383 4.19E-50 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 218 3.4E-27 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 382 9.3E-48 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 PIRSF PIRSF016578 143 366 1.4E-10 T 14-10-2018 D521_1242 c09e0f9d8b3261e9b30ea7acc2cdd2e0 383 PIRSF PIRSF016578 3 82 1.4E-5 T 14-10-2018 D521_2109 63386648412635570945d3f696995cb7 340 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 323 34.137 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 D521_2109 63386648412635570945d3f696995cb7 340 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 313 5.4E-82 T 14-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 D521_2109 63386648412635570945d3f696995cb7 340 Pfam PF02911 Formyl transferase, C-terminal domain 219 313 2.2E-23 T 14-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_2109 63386648412635570945d3f696995cb7 340 SUPERFAMILY SSF50486 222 313 1.47E-25 T 14-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 D521_2109 63386648412635570945d3f696995cb7 340 Gene3D G3DSA:3.10.25.10 222 324 3.1E-26 T 14-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_2109 63386648412635570945d3f696995cb7 340 Gene3D G3DSA:3.40.50.170 1 221 1.2E-71 T 14-10-2018 D521_2109 63386648412635570945d3f696995cb7 340 SUPERFAMILY SSF53328 1 220 4.84E-56 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_2109 63386648412635570945d3f696995cb7 340 Pfam PF00551 Formyl transferase 1 194 5.3E-37 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_1342 660a8caa28e19e9c9558dcabbb770151 281 Gene3D G3DSA:3.40.190.290 72 277 1.3E-25 T 14-10-2018 D521_1342 660a8caa28e19e9c9558dcabbb770151 281 Pfam PF03466 LysR substrate binding domain 67 258 2.1E-28 T 14-10-2018 IPR005119 LysR, substrate-binding D521_1342 660a8caa28e19e9c9558dcabbb770151 281 Gene3D G3DSA:1.10.10.10 1 71 2.1E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1342 660a8caa28e19e9c9558dcabbb770151 281 SUPERFAMILY SSF53850 68 267 2.33E-25 T 14-10-2018 D521_1342 660a8caa28e19e9c9558dcabbb770151 281 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 1 45 1.2E-9 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_1342 660a8caa28e19e9c9558dcabbb770151 281 SUPERFAMILY SSF46785 2 87 3.16E-11 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0902 e2683cf6d0fc62d8d89324bd0fba06d7 285 Gene3D G3DSA:3.40.50.300 4 211 7.6E-27 T 14-10-2018 D521_0902 e2683cf6d0fc62d8d89324bd0fba06d7 285 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 34 178 1.3E-14 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 D521_0902 e2683cf6d0fc62d8d89324bd0fba06d7 285 SMART SM00382 30 188 1.9E-7 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0902 e2683cf6d0fc62d8d89324bd0fba06d7 285 SUPERFAMILY SSF52540 13 271 2.19E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1482 122d34f56f68ecebaf17132004ce43c3 364 SUPERFAMILY SSF55021 267 362 1.9E-25 T 14-10-2018 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 Pfam PF01842 ACT domain 284 347 9.5E-11 T 14-10-2018 IPR002912 ACT domain D521_1482 122d34f56f68ecebaf17132004ce43c3 364 Gene3D G3DSA:3.40.190.10 100 268 1.3E-57 T 14-10-2018 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 Gene3D G3DSA:3.30.70.260 269 364 1.7E-27 T 14-10-2018 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 Gene3D G3DSA:3.40.190.10 178 262 1.3E-57 T 14-10-2018 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 PIRSF PIRSF001500 6 364 8.4E-138 T 14-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 Gene3D G3DSA:1.20.59.10 9 97 2.2E-27 T 14-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 Pfam PF00800 Prephenate dehydratase 98 272 3.2E-60 T 14-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 TIGRFAM TIGR01807 CM_P2: chorismate mutase 13 86 5.4E-26 T 14-10-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 248 270 - T 14-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 Pfam PF01817 Chorismate mutase type II 17 93 1.0E-23 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 SUPERFAMILY SSF48600 12 99 6.23E-21 T 14-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 SMART SM00830 17 96 1.3E-30 T 14-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 D521_1482 122d34f56f68ecebaf17132004ce43c3 364 SUPERFAMILY SSF53850 97 280 5.21E-57 T 14-10-2018 D521_2059 105fd53d030715078fb28ade485d38bd 717 PRINTS PR00458 Haem peroxidase superfamily signature 145 162 5.9E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 D521_2059 105fd53d030715078fb28ade485d38bd 717 PRINTS PR00458 Haem peroxidase superfamily signature 85 99 5.9E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 D521_2059 105fd53d030715078fb28ade485d38bd 717 PRINTS PR00458 Haem peroxidase superfamily signature 163 175 5.9E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 D521_2059 105fd53d030715078fb28ade485d38bd 717 PRINTS PR00458 Haem peroxidase superfamily signature 313 328 5.9E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 D521_2059 105fd53d030715078fb28ade485d38bd 717 PRINTS PR00458 Haem peroxidase superfamily signature 254 269 5.9E-19 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 D521_2059 105fd53d030715078fb28ade485d38bd 717 Gene3D G3DSA:1.10.420.10 573 694 2.9E-142 T 14-10-2018 D521_2059 105fd53d030715078fb28ade485d38bd 717 ProSitePatterns PS00436 Peroxidases active site signature. 85 96 - T 14-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 D521_2059 105fd53d030715078fb28ade485d38bd 717 Gene3D G3DSA:1.10.420.20 186 392 8.7E-217 T 14-10-2018 D521_2059 105fd53d030715078fb28ade485d38bd 717 SUPERFAMILY SSF48113 16 426 1.39E-150 T 14-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 D521_2059 105fd53d030715078fb28ade485d38bd 717 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 7 716 0.0 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 D521_2059 105fd53d030715078fb28ade485d38bd 717 SUPERFAMILY SSF48113 427 716 6.04E-109 T 14-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 D521_2059 105fd53d030715078fb28ade485d38bd 717 Gene3D G3DSA:1.10.520.10 428 716 2.9E-142 T 14-10-2018 D521_2059 105fd53d030715078fb28ade485d38bd 717 Gene3D G3DSA:1.10.520.10 23 427 8.7E-217 T 14-10-2018 D521_2059 105fd53d030715078fb28ade485d38bd 717 Pfam PF00141 Peroxidase 400 693 1.7E-36 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 D521_2059 105fd53d030715078fb28ade485d38bd 717 Pfam PF00141 Peroxidase 64 393 2.3E-51 T 14-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 D521_2059 105fd53d030715078fb28ade485d38bd 717 Hamap MF_01961 Catalase-peroxidase [katG]. 2 717 38.65 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 D521_2059 105fd53d030715078fb28ade485d38bd 717 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 62 87 4.3E-51 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 D521_2059 105fd53d030715078fb28ade485d38bd 717 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 21 43 4.3E-51 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 D521_2059 105fd53d030715078fb28ade485d38bd 717 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 473 499 4.3E-51 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 D521_2059 105fd53d030715078fb28ade485d38bd 717 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 47 60 4.3E-51 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 D521_2059 105fd53d030715078fb28ade485d38bd 717 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 262 285 4.3E-51 T 14-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 D521_1345 4d1ff19b849fd0cb4748a5b91f524d83 373 Pfam PF11737 Protein of unknown function (DUF3300) 51 254 3.8E-70 T 14-10-2018 IPR021728 Protein of unknown function DUF3300 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 Pfam PF08245 Mur ligase middle domain 111 297 2.7E-24 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 Gene3D G3DSA:3.40.1190.10 96 314 1.4E-55 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 Pfam PF02875 Mur ligase family, glutamate ligase domain 318 366 4.1E-10 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 SUPERFAMILY SSF53623 101 316 4.84E-50 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 Gene3D G3DSA:3.40.50.720 1 93 6.6E-36 T 14-10-2018 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 1 464 57.101 T 14-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 Gene3D G3DSA:3.90.190.20 315 468 1.9E-29 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 SUPERFAMILY SSF53244 318 461 2.09E-34 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 Pfam PF01225 Mur ligase family, catalytic domain 2 100 1.7E-19 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 SUPERFAMILY SSF51984 1 93 4.19E-21 T 14-10-2018 D521_0216 ef4383bc33139ee205acaa2212c802c7 468 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 2 463 8.9E-209 T 14-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 D521_0571 2f611b168801f90db7497e84f1aadd90 182 Pfam PF07152 YaeQ protein 1 173 2.3E-77 T 14-10-2018 IPR009822 YaeQ D521_0571 2f611b168801f90db7497e84f1aadd90 182 SMART SM01322 1 176 6.7E-120 T 14-10-2018 IPR009822 YaeQ D521_0571 2f611b168801f90db7497e84f1aadd90 182 SUPERFAMILY SSF52980 5 179 1.26E-72 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 D521_0571 2f611b168801f90db7497e84f1aadd90 182 Gene3D G3DSA:3.10.640.10 1 181 3.7E-80 T 14-10-2018 IPR038590 YaeQ superfamily D521_0571 2f611b168801f90db7497e84f1aadd90 182 PIRSF PIRSF011484 1 181 8.1E-71 T 14-10-2018 IPR009822 YaeQ D521_0250 078c4ea9fd855da237cd0c2751ec7b61 444 Gene3D G3DSA:3.40.50.2000 234 345 8.8E-9 T 14-10-2018 D521_0250 078c4ea9fd855da237cd0c2751ec7b61 444 Gene3D G3DSA:3.40.50.2000 111 233 8.8E-9 T 14-10-2018 D521_0250 078c4ea9fd855da237cd0c2751ec7b61 444 SUPERFAMILY SSF53756 96 409 4.4E-11 T 14-10-2018 D521_1591 16c666e7605a9afb2031838f4c3207b8 211 Pfam PF13683 Integrase core domain 129 195 6.8E-29 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 D521_1591 16c666e7605a9afb2031838f4c3207b8 211 Gene3D G3DSA:3.30.420.10 38 207 4.0E-18 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_1591 16c666e7605a9afb2031838f4c3207b8 211 SUPERFAMILY SSF53098 39 200 6.2E-39 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1599 16c666e7605a9afb2031838f4c3207b8 211 Pfam PF13683 Integrase core domain 129 195 6.8E-29 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 D521_1599 16c666e7605a9afb2031838f4c3207b8 211 Gene3D G3DSA:3.30.420.10 38 207 4.0E-18 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_1599 16c666e7605a9afb2031838f4c3207b8 211 SUPERFAMILY SSF53098 39 200 6.2E-39 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1238 8346a2c5c9254fdbc5d014f1c04da988 323 PIRSF PIRSF017082 2 323 2.5E-83 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1238 8346a2c5c9254fdbc5d014f1c04da988 323 SUPERFAMILY SSF53850 109 283 6.88E-12 T 14-10-2018 D521_1238 8346a2c5c9254fdbc5d014f1c04da988 323 Gene3D G3DSA:3.40.190.150 28 313 1.3E-112 T 14-10-2018 D521_1238 8346a2c5c9254fdbc5d014f1c04da988 323 Gene3D G3DSA:3.40.190.10 125 248 1.3E-112 T 14-10-2018 D521_1238 8346a2c5c9254fdbc5d014f1c04da988 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 9.2E-85 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1511 6e716cef640053e6180a0831fa8890c9 309 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 276 3.6E-52 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 D521_1511 6e716cef640053e6180a0831fa8890c9 309 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 42 307 2.8E-23 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 D521_1511 6e716cef640053e6180a0831fa8890c9 309 SUPERFAMILY SSF52283 14 132 7.94E-25 T 14-10-2018 D521_1511 6e716cef640053e6180a0831fa8890c9 309 SUPERFAMILY SSF51735 99 276 3.78E-50 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1511 6e716cef640053e6180a0831fa8890c9 309 Gene3D G3DSA:3.40.50.720 43 302 4.9E-99 T 14-10-2018 D521_1511 6e716cef640053e6180a0831fa8890c9 309 Gene3D G3DSA:3.40.50.720 97 279 4.9E-99 T 14-10-2018 D521_1264 c931c92af90c35d4380dcc81fb6b9d05 162 Pfam PF00293 NUDIX domain 42 151 3.2E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 D521_1264 c931c92af90c35d4380dcc81fb6b9d05 162 ProSitePatterns PS00893 Nudix box signature. 65 86 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 D521_1264 c931c92af90c35d4380dcc81fb6b9d05 162 PRINTS PR00502 NUDIX hydrolase family signature 60 74 3.4E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 D521_1264 c931c92af90c35d4380dcc81fb6b9d05 162 PRINTS PR00502 NUDIX hydrolase family signature 74 89 3.4E-6 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 D521_1264 c931c92af90c35d4380dcc81fb6b9d05 162 SUPERFAMILY SSF55811 35 160 1.21E-22 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 D521_1264 c931c92af90c35d4380dcc81fb6b9d05 162 Gene3D G3DSA:3.90.79.10 8 162 2.6E-37 T 14-10-2018 D521_1167 4f3938fcd14eb72dd99c97c6c75689f2 169 SUPERFAMILY SSF47741 88 156 6.67E-28 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily D521_1167 4f3938fcd14eb72dd99c97c6c75689f2 169 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 43 51 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 D521_1167 4f3938fcd14eb72dd99c97c6c75689f2 169 Pfam PF01799 [2Fe-2S] binding domain 77 149 5.2E-27 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 D521_1167 4f3938fcd14eb72dd99c97c6c75689f2 169 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 57 4.2E-6 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 D521_1167 4f3938fcd14eb72dd99c97c6c75689f2 169 Gene3D G3DSA:1.10.150.120 80 167 1.8E-29 T 14-10-2018 D521_1167 4f3938fcd14eb72dd99c97c6c75689f2 169 SUPERFAMILY SSF54292 6 82 2.62E-21 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 D521_1167 4f3938fcd14eb72dd99c97c6c75689f2 169 Gene3D G3DSA:3.10.20.30 1 79 7.9E-28 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_1828 5db050af3c637429ad9a4dc194686449 389 PIRSF PIRSF001554 1 388 1.6E-150 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 D521_1828 5db050af3c637429ad9a4dc194686449 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 14-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 D521_1828 5db050af3c637429ad9a4dc194686449 389 SUPERFAMILY SSF56059 1 238 8.13E-82 T 14-10-2018 D521_1828 5db050af3c637429ad9a4dc194686449 389 Gene3D G3DSA:3.30.470.20 1 234 4.2E-93 T 14-10-2018 D521_1828 5db050af3c637429ad9a4dc194686449 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 4.6E-158 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 D521_1828 5db050af3c637429ad9a4dc194686449 389 Pfam PF00549 CoA-ligase 262 382 2.5E-25 T 14-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 D521_1828 5db050af3c637429ad9a4dc194686449 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 43.075 T 14-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 D521_1828 5db050af3c637429ad9a4dc194686449 389 SUPERFAMILY SSF52210 241 384 1.27E-52 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 D521_1828 5db050af3c637429ad9a4dc194686449 389 Gene3D G3DSA:3.40.50.261 240 387 5.3E-56 T 14-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 D521_1828 5db050af3c637429ad9a4dc194686449 389 Gene3D G3DSA:3.30.1490.20 21 104 4.2E-93 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 D521_1828 5db050af3c637429ad9a4dc194686449 389 Pfam PF08442 ATP-grasp domain 2 202 1.4E-79 T 14-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 D521_1745 9db84b392ddd7d9be8fffa5165015d37 252 SUPERFAMILY SSF52540 60 229 2.22E-20 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1745 9db84b392ddd7d9be8fffa5165015d37 252 Gene3D G3DSA:1.10.8.60 185 250 1.7E-25 T 14-10-2018 D521_1745 9db84b392ddd7d9be8fffa5165015d37 252 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 117 131 2.9E-5 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like D521_1745 9db84b392ddd7d9be8fffa5165015d37 252 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 59 79 2.9E-5 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like D521_1745 9db84b392ddd7d9be8fffa5165015d37 252 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 149 176 2.9E-5 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like D521_1745 9db84b392ddd7d9be8fffa5165015d37 252 Pfam PF00308 Bacterial dnaA protein 38 233 2.4E-11 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA D521_1745 9db84b392ddd7d9be8fffa5165015d37 252 Gene3D G3DSA:3.40.50.300 54 181 2.0E-21 T 14-10-2018 D521_1745 9db84b392ddd7d9be8fffa5165015d37 252 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 9 250 9.0E-61 T 14-10-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 D521_0186 3425f5ca75d761353cb40dbe544c1f91 352 Gene3D G3DSA:1.20.81.30 201 316 4.8E-15 T 14-10-2018 D521_0186 3425f5ca75d761353cb40dbe544c1f91 352 Gene3D G3DSA:1.20.81.30 1 116 1.0E-22 T 14-10-2018 D521_0186 3425f5ca75d761353cb40dbe544c1f91 352 Pfam PF00482 Type II secretion system (T2SS), protein F 218 344 1.8E-20 T 14-10-2018 IPR018076 Type II secretion system F domain D521_0186 3425f5ca75d761353cb40dbe544c1f91 352 Pfam PF00482 Type II secretion system (T2SS), protein F 15 137 1.2E-24 T 14-10-2018 IPR018076 Type II secretion system F domain D521_1917 bc4b9b812de14d4e9bda85fca771a52a 322 Gene3D G3DSA:3.40.50.2020 13 309 3.9E-128 T 14-10-2018 D521_1917 bc4b9b812de14d4e9bda85fca771a52a 322 Gene3D G3DSA:3.40.50.2020 155 297 3.9E-128 T 14-10-2018 D521_1917 bc4b9b812de14d4e9bda85fca771a52a 322 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 136 151 - T 14-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 D521_1917 bc4b9b812de14d4e9bda85fca771a52a 322 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 11 125 2.5E-47 T 14-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 D521_1917 bc4b9b812de14d4e9bda85fca771a52a 322 Pfam PF14572 Phosphoribosyl synthetase-associated domain 211 320 3.8E-25 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 D521_1917 bc4b9b812de14d4e9bda85fca771a52a 322 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 11 320 1.7E-120 T 14-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 D521_1917 bc4b9b812de14d4e9bda85fca771a52a 322 SUPERFAMILY SSF53271 16 101 1.41E-7 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like D521_1917 bc4b9b812de14d4e9bda85fca771a52a 322 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 10 321 47.272 T 14-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 D521_1917 bc4b9b812de14d4e9bda85fca771a52a 322 SMART SM01400 10 127 5.9E-74 T 14-10-2018 D521_1917 bc4b9b812de14d4e9bda85fca771a52a 322 SUPERFAMILY SSF53271 75 311 5.47E-62 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like D521_1431 9ffd2f0a2821b29a0a368c8f9f108fcf 59 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 3.9E-20 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1431 9ffd2f0a2821b29a0a368c8f9f108fcf 59 Pfam PF01783 Ribosomal L32p protein family 2 55 1.6E-18 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1431 9ffd2f0a2821b29a0a368c8f9f108fcf 59 SUPERFAMILY SSF57829 2 55 4.7E-17 T 14-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 D521_1431 9ffd2f0a2821b29a0a368c8f9f108fcf 59 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.113 T 14-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 Gene3D G3DSA:3.30.565.10 277 432 3.9E-35 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 SUPERFAMILY SSF47384 193 272 1.9E-20 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 Pfam PF13188 PAS domain 102 151 1.3E-6 T 14-10-2018 IPR000014 PAS domain D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 271 1.6E-19 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 SMART SM00388 206 272 2.7E-22 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 Gene3D G3DSA:1.10.287.130 193 273 3.1E-23 T 14-10-2018 D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 SUPERFAMILY SSF55785 85 153 8.58E-7 T 14-10-2018 IPR035965 PAS domain superfamily D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 94 425 3.1E-124 T 14-10-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 428 1.5E-21 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 SUPERFAMILY SSF55874 261 427 6.02E-38 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 382 1.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 1.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 426 1.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 407 1.2E-14 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 SMART SM00387 316 429 3.6E-34 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_0793 87632fcaa909e2ccfe9e50fa7aaebc52 435 Gene3D G3DSA:3.30.450.20 80 173 4.9E-5 T 14-10-2018 D521_1496 8f3428880b7a15a92ae7197f73cf3341 183 Gene3D G3DSA:1.20.1290.10 36 178 4.8E-33 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 D521_1496 8f3428880b7a15a92ae7197f73cf3341 183 Pfam PF02627 Carboxymuconolactone decarboxylase family 45 108 4.6E-8 T 14-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 D521_1496 8f3428880b7a15a92ae7197f73cf3341 183 SUPERFAMILY SSF69118 17 180 4.51E-30 T 14-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 D521_1309 00db897ba49c9315130b991bc7c81adb 69 SUPERFAMILY SSF47413 7 63 2.19E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 D521_1309 00db897ba49c9315130b991bc7c81adb 69 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 2 64 2.2E-15 T 14-10-2018 IPR014057 Uncharacterized protein HI1420 D521_0754 63870a4c73835322d5a82e96072051e0 163 SUPERFAMILY SSF54862 37 146 1.3E-27 T 14-10-2018 D521_0754 63870a4c73835322d5a82e96072051e0 163 Pfam PF12838 4Fe-4S dicluster domain 63 117 6.5E-14 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_0754 63870a4c73835322d5a82e96072051e0 163 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 20 141 3.5E-47 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0754 63870a4c73835322d5a82e96072051e0 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 103 114 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_0754 63870a4c73835322d5a82e96072051e0 163 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 11 160 28.522 T 14-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0754 63870a4c73835322d5a82e96072051e0 163 Gene3D G3DSA:3.30.70.3270 37 162 1.0E-39 T 14-10-2018 D521_0754 63870a4c73835322d5a82e96072051e0 163 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1026 fd825133d9a31bb6a973c6a2826e8311 186 Pfam PF00293 NUDIX domain 39 150 9.6E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 D521_1026 fd825133d9a31bb6a973c6a2826e8311 186 SUPERFAMILY SSF55811 2 162 5.28E-37 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 D521_1026 fd825133d9a31bb6a973c6a2826e8311 186 ProSitePatterns PS00893 Nudix box signature. 70 91 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 D521_1026 fd825133d9a31bb6a973c6a2826e8311 186 Gene3D G3DSA:2.20.70.10 1 35 1.8E-15 T 14-10-2018 D521_1026 fd825133d9a31bb6a973c6a2826e8311 186 Pfam PF14803 Nudix N-terminal 2 34 4.3E-16 T 14-10-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 D521_1026 fd825133d9a31bb6a973c6a2826e8311 186 Gene3D G3DSA:3.90.79.10 36 174 1.3E-33 T 14-10-2018 D521_1841 1fa975aaf3a05712aa934997a18c357b 366 Gene3D G3DSA:3.40.190.170 37 345 1.3E-125 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily D521_1841 1fa975aaf3a05712aa934997a18c357b 366 Gene3D G3DSA:3.40.190.10 160 332 1.3E-125 T 14-10-2018 D521_1841 1fa975aaf3a05712aa934997a18c357b 366 SUPERFAMILY SSF53850 150 244 2.17E-5 T 14-10-2018 D521_1841 1fa975aaf3a05712aa934997a18c357b 366 PIRSF PIRSF039026 3 365 4.7E-127 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like D521_1841 1fa975aaf3a05712aa934997a18c357b 366 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 58 328 3.6E-55 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 254 266 - T 14-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 SMART SM01004 11 335 7.8E-241 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 162 181 3.3E-58 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 254 270 3.3E-58 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 279 294 3.3E-58 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 309 328 3.3E-58 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 200 219 3.3E-58 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 131 145 3.3E-58 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 SUPERFAMILY SSF51569 7 336 2.93E-144 T 14-10-2018 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 Gene3D G3DSA:3.20.20.70 3 339 5.0E-146 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 PIRSF PIRSF001415 4 338 6.2E-149 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 D521_0082 6eb32c072a0052e6fb1a281a70f2f0a9 339 Pfam PF00490 Delta-aminolevulinic acid dehydratase 14 333 3.2E-141 T 14-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 D521_1529 bc2fa973b808ec353a0eb544a8be57f0 59 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 2.7E-20 T 14-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type D521_1529 bc2fa973b808ec353a0eb544a8be57f0 59 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 47 6.2E-20 T 14-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type D521_1383 4130970ca072dd32b5853c9a4f4a23c7 480 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 97 344 9.9E-11 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme D521_1383 4130970ca072dd32b5853c9a4f4a23c7 480 Gene3D G3DSA:3.40.50.1100 112 447 9.3E-137 T 14-10-2018 D521_1383 4130970ca072dd32b5853c9a4f4a23c7 480 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 114 128 - T 14-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 D521_1383 4130970ca072dd32b5853c9a4f4a23c7 480 Pfam PF14821 Threonine synthase N terminus 2 79 1.8E-29 T 14-10-2018 IPR029144 Threonine synthase, N-terminal D521_1383 4130970ca072dd32b5853c9a4f4a23c7 480 Gene3D G3DSA:3.90.1380.10 1 94 5.5E-33 T 14-10-2018 IPR037158 Threonine synthase, N-terminal domain superfamily D521_1383 4130970ca072dd32b5853c9a4f4a23c7 480 SUPERFAMILY SSF53686 1 478 1.01E-148 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme D521_1383 4130970ca072dd32b5853c9a4f4a23c7 480 Gene3D G3DSA:3.40.50.1100 120 460 9.3E-137 T 14-10-2018 D521_1383 4130970ca072dd32b5853c9a4f4a23c7 480 TIGRFAM TIGR00260 thrC: threonine synthase 107 442 2.5E-70 T 14-10-2018 IPR004450 Threonine synthase-like D521_1587 9bedda909c1b085627ddff485f9d1b31 266 SUPERFAMILY SSF53098 103 261 1.39E-40 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1587 9bedda909c1b085627ddff485f9d1b31 266 Pfam PF00665 Integrase core domain 110 221 9.5E-27 T 14-10-2018 IPR001584 Integrase, catalytic core GO:0015074 D521_1587 9bedda909c1b085627ddff485f9d1b31 266 Gene3D G3DSA:3.30.420.10 106 252 4.0E-21 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_0834 302a8e68442df863641338d9f479e3b3 679 SUPERFAMILY SSF55021 604 678 1.65E-8 T 14-10-2018 D521_0834 302a8e68442df863641338d9f479e3b3 679 Gene3D G3DSA:3.10.20.30 387 455 3.1E-27 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_0834 302a8e68442df863641338d9f479e3b3 679 SUPERFAMILY SSF81271 382 449 3.49E-20 T 14-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 D521_0834 302a8e68442df863641338d9f479e3b3 679 Pfam PF13291 ACT domain 603 678 3.5E-14 T 14-10-2018 IPR002912 ACT domain D521_0834 302a8e68442df863641338d9f479e3b3 679 Pfam PF02824 TGS domain 391 449 1.7E-20 T 14-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 D521_0834 302a8e68442df863641338d9f479e3b3 679 Gene3D G3DSA:3.30.70.260 604 679 5.0E-13 T 14-10-2018 D521_0834 302a8e68442df863641338d9f479e3b3 679 SMART SM00954 215 325 1.2E-63 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 D521_0834 302a8e68442df863641338d9f479e3b3 679 SUPERFAMILY SSF109604 18 170 2.57E-25 T 14-10-2018 D521_0834 302a8e68442df863641338d9f479e3b3 679 Gene3D G3DSA:3.30.460.10 173 305 8.9E-50 T 14-10-2018 D521_0834 302a8e68442df863641338d9f479e3b3 679 Pfam PF13328 HD domain 19 156 2.5E-28 T 14-10-2018 IPR003607 HD/PDEase domain D521_0834 302a8e68442df863641338d9f479e3b3 679 SUPERFAMILY SSF81301 172 325 2.94E-58 T 14-10-2018 D521_0834 302a8e68442df863641338d9f479e3b3 679 Gene3D G3DSA:1.10.3210.10 12 171 4.4E-27 T 14-10-2018 D521_0834 302a8e68442df863641338d9f479e3b3 679 Pfam PF04607 Region found in RelA / SpoT proteins 215 324 2.0E-37 T 14-10-2018 IPR007685 RelA/SpoT GO:0015969 D521_1515 46e1d6a5dd4c3c20675b85a29584f9b5 377 SMART SM00922 149 247 3.0E-26 T 14-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal D521_1515 46e1d6a5dd4c3c20675b85a29584f9b5 377 SUPERFAMILY SSF51604 115 368 5.76E-73 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily D521_1515 46e1d6a5dd4c3c20675b85a29584f9b5 377 SUPERFAMILY SSF54826 4 128 7.71E-27 T 14-10-2018 D521_1515 46e1d6a5dd4c3c20675b85a29584f9b5 377 Pfam PF13378 Enolase C-terminal domain-like 153 362 1.9E-59 T 14-10-2018 IPR029065 Enolase C-terminal domain-like D521_1515 46e1d6a5dd4c3c20675b85a29584f9b5 377 Gene3D G3DSA:3.30.390.10 2 125 3.0E-28 T 14-10-2018 IPR029017 Enolase-like, N-terminal D521_1515 46e1d6a5dd4c3c20675b85a29584f9b5 377 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 7 127 2.2E-16 T 14-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain D521_1515 46e1d6a5dd4c3c20675b85a29584f9b5 377 Gene3D G3DSA:3.20.20.120 126 359 3.2E-73 T 14-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily D521_0111 5647b15648a9d6f1875cac24cd2775c9 252 Pfam PF00977 Histidine biosynthesis protein 5 235 3.0E-88 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 D521_0111 5647b15648a9d6f1875cac24cd2775c9 252 SUPERFAMILY SSF51366 2 251 3.45E-82 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 D521_0111 5647b15648a9d6f1875cac24cd2775c9 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 251 48.509 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 D521_0111 5647b15648a9d6f1875cac24cd2775c9 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 2 251 2.7E-113 T 14-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 D521_0111 5647b15648a9d6f1875cac24cd2775c9 252 Gene3D G3DSA:3.20.20.70 1 252 9.8E-109 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0580 806ca1712bd783babce5bd8b912a2802 515 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 116 513 2.4E-153 T 14-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 D521_0580 806ca1712bd783babce5bd8b912a2802 515 Gene3D G3DSA:3.90.1210.30 13 90 2.3E-18 T 14-10-2018 D521_0580 806ca1712bd783babce5bd8b912a2802 515 SMART SM00858 20 89 2.0E-5 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 D521_0883 34778aa74d1f615f2d33b3b49e4c56da 307 SUPERFAMILY SSF53850 89 297 4.16E-42 T 14-10-2018 D521_0883 34778aa74d1f615f2d33b3b49e4c56da 307 Gene3D G3DSA:3.40.190.10 163 264 2.8E-60 T 14-10-2018 D521_0883 34778aa74d1f615f2d33b3b49e4c56da 307 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 62 3.5E-18 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_0883 34778aa74d1f615f2d33b3b49e4c56da 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_0883 34778aa74d1f615f2d33b3b49e4c56da 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_0883 34778aa74d1f615f2d33b3b49e4c56da 307 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.2E-5 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_0883 34778aa74d1f615f2d33b3b49e4c56da 307 Gene3D G3DSA:1.10.10.10 3 91 2.8E-24 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0883 34778aa74d1f615f2d33b3b49e4c56da 307 SUPERFAMILY SSF46785 5 111 5.06E-21 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0883 34778aa74d1f615f2d33b3b49e4c56da 307 Gene3D G3DSA:3.40.190.10 92 290 2.8E-60 T 14-10-2018 D521_0883 34778aa74d1f615f2d33b3b49e4c56da 307 Pfam PF03466 LysR substrate binding domain 89 293 2.2E-41 T 14-10-2018 IPR005119 LysR, substrate-binding D521_1278 3a6cd96e1e8271eb5fa1dfbacda0d356 775 SMART SM00327 266 427 5.9E-17 T 14-10-2018 IPR002035 von Willebrand factor, type A D521_1278 3a6cd96e1e8271eb5fa1dfbacda0d356 775 SMART SM00609 4 132 0.0028 T 14-10-2018 IPR013694 VIT domain D521_1278 3a6cd96e1e8271eb5fa1dfbacda0d356 775 Gene3D G3DSA:3.40.50.410 271 436 5.1E-25 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily D521_1278 3a6cd96e1e8271eb5fa1dfbacda0d356 775 SUPERFAMILY SSF53300 267 425 1.48E-24 T 14-10-2018 IPR036465 von Willebrand factor A-like domain superfamily D521_1278 3a6cd96e1e8271eb5fa1dfbacda0d356 775 Pfam PF13768 von Willebrand factor type A domain 269 417 7.8E-17 T 14-10-2018 IPR002035 von Willebrand factor, type A D521_1278 3a6cd96e1e8271eb5fa1dfbacda0d356 775 Pfam PF08487 Vault protein inter-alpha-trypsin domain 27 130 4.7E-22 T 14-10-2018 IPR013694 VIT domain D521_2003 839df6fc180032cc0e71ed96fb1e2075 276 SUPERFAMILY SSF51730 3 273 1.96E-89 T 14-10-2018 IPR029041 FAD-linked oxidoreductase-like D521_2003 839df6fc180032cc0e71ed96fb1e2075 276 Pfam PF02219 Methylenetetrahydrofolate reductase 3 272 1.2E-80 T 14-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 D521_2003 839df6fc180032cc0e71ed96fb1e2075 276 Gene3D G3DSA:3.20.20.220 1 276 3.9E-91 T 14-10-2018 D521_2003 839df6fc180032cc0e71ed96fb1e2075 276 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 3 272 2.4E-93 T 14-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 SUPERFAMILY SSF48163 318 477 2.62E-37 T 14-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 18 477 4.0E-164 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 24 35 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 18 324 1.5E-98 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 Gene3D G3DSA:1.10.10.350 393 479 4.4E-15 T 14-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 17 479 30.138 T 14-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 46 2.6E-24 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 33 2.6E-24 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 PRINTS PR00987 Glutamyl-tRNA synthetase signature 50 63 2.6E-24 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 PRINTS PR00987 Glutamyl-tRNA synthetase signature 198 208 2.6E-24 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 PRINTS PR00987 Glutamyl-tRNA synthetase signature 214 222 2.6E-24 T 14-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 Gene3D G3DSA:3.40.50.620 16 333 2.2E-132 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 SUPERFAMILY SSF52374 18 315 3.18E-107 T 14-10-2018 D521_0945 3511f7bb1579535a60aaa5d5143e7685 479 Gene3D G3DSA:1.10.8.70 334 392 1.1E-10 T 14-10-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 D521_2075 1b07474b46697d8578f93770abdb51eb 349 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 14-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 D521_2075 1b07474b46697d8578f93770abdb51eb 349 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 179 207 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 D521_2075 1b07474b46697d8578f93770abdb51eb 349 Pfam PF00107 Zinc-binding dehydrogenase 186 309 2.0E-23 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 D521_2075 1b07474b46697d8578f93770abdb51eb 349 SUPERFAMILY SSF50129 10 173 9.89E-47 T 14-10-2018 IPR011032 GroES-like superfamily D521_2075 1b07474b46697d8578f93770abdb51eb 349 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 143 3.8E-26 T 14-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 D521_2075 1b07474b46697d8578f93770abdb51eb 349 Gene3D G3DSA:3.40.50.720 160 315 1.4E-130 T 14-10-2018 D521_2075 1b07474b46697d8578f93770abdb51eb 349 Gene3D G3DSA:3.90.180.10 13 343 1.4E-130 T 14-10-2018 D521_2075 1b07474b46697d8578f93770abdb51eb 349 SUPERFAMILY SSF51735 154 313 3.33E-41 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0575 ad1d6b7f410a515ce863430e95ce7c6d 199 Pfam PF13671 AAA domain 12 169 3.4E-21 T 14-10-2018 D521_0575 ad1d6b7f410a515ce863430e95ce7c6d 199 Gene3D G3DSA:3.40.50.300 8 199 4.2E-21 T 14-10-2018 D521_0575 ad1d6b7f410a515ce863430e95ce7c6d 199 SUPERFAMILY SSF52540 10 178 6.53E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1759 0ee30d76bb97433984562ffda5154e40 277 Pfam PF00795 Carbon-nitrogen hydrolase 13 266 4.0E-50 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 D521_1759 0ee30d76bb97433984562ffda5154e40 277 Gene3D G3DSA:3.60.110.10 3 277 3.4E-81 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily D521_1759 0ee30d76bb97433984562ffda5154e40 277 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 162 182 - T 14-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site D521_1759 0ee30d76bb97433984562ffda5154e40 277 SUPERFAMILY SSF56317 10 275 1.27E-71 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily D521_2088 3347f848411ea72577a71ab123ca229b 514 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 307 329 1.4E-21 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 D521_2088 3347f848411ea72577a71ab123ca229b 514 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 58 70 1.4E-21 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 D521_2088 3347f848411ea72577a71ab123ca229b 514 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 330 344 1.4E-21 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 D521_2088 3347f848411ea72577a71ab123ca229b 514 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 92 111 1.4E-21 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 D521_2088 3347f848411ea72577a71ab123ca229b 514 SUPERFAMILY SSF53335 32 379 8.86E-75 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_2088 3347f848411ea72577a71ab123ca229b 514 PIRSF PIRSF015855 3 434 9.0E-113 T 14-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 D521_2088 3347f848411ea72577a71ab123ca229b 514 Pfam PF01555 DNA methylase 58 362 8.9E-54 T 14-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 D521_2088 3347f848411ea72577a71ab123ca229b 514 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 61 67 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 D521_0004 70544b5db200c6e792c5d542f1891077 164 SMART SM00317 14 136 8.2E-26 T 14-10-2018 IPR001214 SET domain GO:0005515 D521_0004 70544b5db200c6e792c5d542f1891077 164 Pfam PF00856 SET domain 25 129 3.9E-15 T 14-10-2018 IPR001214 SET domain GO:0005515 D521_0004 70544b5db200c6e792c5d542f1891077 164 Gene3D G3DSA:2.170.270.10 4 162 9.1E-46 T 14-10-2018 D521_0004 70544b5db200c6e792c5d542f1891077 164 SUPERFAMILY SSF82199 14 156 4.84E-42 T 14-10-2018 D521_0177 4e55d99be5c6deb5eb7244710cc884c8 304 SUPERFAMILY SSF54211 2 125 7.59E-40 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0177 4e55d99be5c6deb5eb7244710cc884c8 304 Gene3D G3DSA:3.30.230.20 1 127 6.7E-47 T 14-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 D521_0177 4e55d99be5c6deb5eb7244710cc884c8 304 Gene3D G3DSA:3.30.1700.10 128 303 1.4E-66 T 14-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 D521_0177 4e55d99be5c6deb5eb7244710cc884c8 304 SUPERFAMILY SSF54211 133 278 3.03E-52 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0177 4e55d99be5c6deb5eb7244710cc884c8 304 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 1.1E-107 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 D521_0177 4e55d99be5c6deb5eb7244710cc884c8 304 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 279 46.26 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 D521_0177 4e55d99be5c6deb5eb7244710cc884c8 304 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 289 1.1E-114 T 14-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 D521_1502 9eec368995676acb579ff5142fdc2f16 323 Gene3D G3DSA:3.40.190.10 125 248 2.5E-110 T 14-10-2018 D521_1502 9eec368995676acb579ff5142fdc2f16 323 SUPERFAMILY SSF53850 120 285 6.39E-15 T 14-10-2018 D521_1502 9eec368995676acb579ff5142fdc2f16 323 Gene3D G3DSA:3.40.190.150 27 313 2.5E-110 T 14-10-2018 D521_1502 9eec368995676acb579ff5142fdc2f16 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 48 319 1.8E-88 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1502 9eec368995676acb579ff5142fdc2f16 323 PIRSF PIRSF017082 1 322 3.8E-82 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1318 249536303d7e43d4e4fa602fa2788887 231 Pfam PF00005 ABC transporter 28 176 1.8E-31 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_1318 249536303d7e43d4e4fa602fa2788887 231 SUPERFAMILY SSF52540 8 227 2.52E-66 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1318 249536303d7e43d4e4fa602fa2788887 231 SMART SM00382 37 225 2.8E-12 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1318 249536303d7e43d4e4fa602fa2788887 231 Gene3D G3DSA:3.40.50.300 6 231 1.2E-64 T 14-10-2018 D521_1318 249536303d7e43d4e4fa602fa2788887 231 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0977 07a52ee58b93233cd1f85cdcee4d2e84 322 Gene3D G3DSA:3.60.15.10 38 280 2.9E-52 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_0977 07a52ee58b93233cd1f85cdcee4d2e84 322 SMART SM00849 65 251 1.0E-26 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0977 07a52ee58b93233cd1f85cdcee4d2e84 322 Pfam PF00753 Metallo-beta-lactamase superfamily 64 251 1.6E-25 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0977 07a52ee58b93233cd1f85cdcee4d2e84 322 SUPERFAMILY SSF56281 37 306 6.02E-58 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_1438 012d58b760986050d0e33a7880fbf107 879 Hamap MF_00970 Ribonuclease E [rne]. 1 860 32.851 T 14-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 D521_1438 012d58b760986050d0e33a7880fbf107 879 Pfam PF00575 S1 RNA binding domain 36 116 1.3E-11 T 14-10-2018 IPR003029 S1 domain GO:0003676 D521_1438 012d58b760986050d0e33a7880fbf107 879 Pfam PF10150 Ribonuclease E/G family 120 389 3.6E-93 T 14-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 D521_1438 012d58b760986050d0e33a7880fbf107 879 SMART SM00316 37 118 1.1E-9 T 14-10-2018 IPR022967 RNA-binding domain, S1 D521_1438 012d58b760986050d0e33a7880fbf107 879 Gene3D G3DSA:2.40.50.140 31 124 1.1E-30 T 14-10-2018 D521_1438 012d58b760986050d0e33a7880fbf107 879 SUPERFAMILY SSF50249 39 124 1.61E-17 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1438 012d58b760986050d0e33a7880fbf107 879 Gene3D G3DSA:3.40.1260.20 399 509 4.9E-38 T 14-10-2018 D521_1438 012d58b760986050d0e33a7880fbf107 879 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 423 2.5E-158 T 14-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 D521_0516 7b35d4194405ed7eaca0a71767a62b6e 177 SUPERFAMILY SSF51283 23 176 1.96E-47 T 14-10-2018 IPR036157 dUTPase-like superfamily D521_0516 7b35d4194405ed7eaca0a71767a62b6e 177 Gene3D G3DSA:2.70.40.10 1 149 1.7E-47 T 14-10-2018 IPR036157 dUTPase-like superfamily D521_0516 7b35d4194405ed7eaca0a71767a62b6e 177 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 27 176 7.4E-45 T 14-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 D521_0516 7b35d4194405ed7eaca0a71767a62b6e 177 Pfam PF00692 dUTPase 71 172 1.5E-5 T 14-10-2018 IPR029054 dUTPase-like D521_0799 a297491f6c6dfdd99db4a7fe30a88d4f 149 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 1 115 3.3E-6 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I D521_0799 a297491f6c6dfdd99db4a7fe30a88d4f 149 SUPERFAMILY SSF52788 1 124 2.62E-25 T 14-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily D521_0799 a297491f6c6dfdd99db4a7fe30a88d4f 149 Gene3D G3DSA:3.40.50.2300 1 124 2.0E-26 T 14-10-2018 D521_0799 a297491f6c6dfdd99db4a7fe30a88d4f 149 SMART SM00226 1 124 1.4E-7 T 14-10-2018 IPR023485 Phosphotyrosine protein phosphatase I D521_0031 484926d503d90979301cbd322dd2ea57 200 Gene3D G3DSA:3.40.50.10490 5 200 1.8E-77 T 14-10-2018 D521_0031 484926d503d90979301cbd322dd2ea57 200 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 8 198 37.533 T 14-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 D521_0031 484926d503d90979301cbd322dd2ea57 200 Pfam PF13580 SIS domain 26 152 5.3E-34 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 D521_0031 484926d503d90979301cbd322dd2ea57 200 SUPERFAMILY SSF53697 13 197 1.25E-56 T 14-10-2018 D521_0130 61741987ea6982ec106e505c0cfc47d5 438 ProSitePatterns PS00216 Sugar transport proteins signature 1. 302 318 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 D521_0130 61741987ea6982ec106e505c0cfc47d5 438 Pfam PF00083 Sugar (and other) transporter 19 239 5.0E-32 T 14-10-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 D521_0130 61741987ea6982ec106e505c0cfc47d5 438 Pfam PF07690 Major Facilitator Superfamily 276 432 3.0E-9 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_0130 61741987ea6982ec106e505c0cfc47d5 438 Gene3D G3DSA:1.20.1250.20 17 438 6.1E-69 T 14-10-2018 D521_0130 61741987ea6982ec106e505c0cfc47d5 438 SUPERFAMILY SSF103473 17 433 1.44E-61 T 14-10-2018 IPR036259 MFS transporter superfamily D521_0130 61741987ea6982ec106e505c0cfc47d5 438 ProSitePatterns PS00217 Sugar transport proteins signature 2. 129 154 - T 14-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 D521_0127 1d07b35bfbc4c0f785afd4fd4d6b5f3c 225 Gene3D G3DSA:3.90.550.10 6 222 3.5E-9 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0127 1d07b35bfbc4c0f785afd4fd4d6b5f3c 225 SUPERFAMILY SSF53448 5 220 1.49E-22 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0127 1d07b35bfbc4c0f785afd4fd4d6b5f3c 225 Pfam PF01501 Glycosyl transferase family 8 40 116 5.8E-7 T 14-10-2018 IPR002495 Glycosyl transferase, family 8 GO:0016757 D521_1509 40c15f975b4164f4949654f8f1ff2fc2 227 Pfam PF01292 Prokaryotic cytochrome b561 8 178 5.9E-19 T 14-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 D521_1509 40c15f975b4164f4949654f8f1ff2fc2 227 Gene3D G3DSA:1.20.950.20 2 167 1.4E-16 T 14-10-2018 D521_1509 40c15f975b4164f4949654f8f1ff2fc2 227 SUPERFAMILY SSF81342 4 184 1.21E-36 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 D521_0039 1e33e105b9f702068575af739a392c5c 190 SMART SM00738 15 124 1.0E-43 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 D521_0039 1e33e105b9f702068575af739a392c5c 190 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 15 190 25.385 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 D521_0039 1e33e105b9f702068575af739a392c5c 190 SUPERFAMILY SSF82679 16 125 1.44E-37 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 D521_0039 1e33e105b9f702068575af739a392c5c 190 ProSitePatterns PS01014 Transcription termination factor nusG signature. 173 182 - T 14-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site D521_0039 1e33e105b9f702068575af739a392c5c 190 SUPERFAMILY SSF50104 134 189 6.02E-19 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily D521_0039 1e33e105b9f702068575af739a392c5c 190 Pfam PF02357 Transcription termination factor nusG 16 121 6.2E-26 T 14-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 D521_0039 1e33e105b9f702068575af739a392c5c 190 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 18 190 3.7E-68 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 D521_0039 1e33e105b9f702068575af739a392c5c 190 Gene3D G3DSA:3.30.70.940 11 130 2.5E-45 T 14-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 D521_0039 1e33e105b9f702068575af739a392c5c 190 Gene3D G3DSA:2.30.30.30 131 190 8.1E-25 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 D521_0039 1e33e105b9f702068575af739a392c5c 190 PRINTS PR00338 Transcription termination factor NUSG signature 148 163 2.7E-19 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 D521_0039 1e33e105b9f702068575af739a392c5c 190 PRINTS PR00338 Transcription termination factor NUSG signature 70 82 2.7E-19 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 D521_0039 1e33e105b9f702068575af739a392c5c 190 PRINTS PR00338 Transcription termination factor NUSG signature 166 182 2.7E-19 T 14-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 D521_0039 1e33e105b9f702068575af739a392c5c 190 Pfam PF00467 KOW motif 139 173 3.8E-6 T 14-10-2018 IPR005824 KOW D521_0039 1e33e105b9f702068575af739a392c5c 190 SMART SM00739 136 163 2.2E-5 T 14-10-2018 IPR005824 KOW D521_0975 d7bb027e50cd91a024d0e8937977ee56 373 Pfam PF04143 Sulphur transport 30 358 4.7E-56 T 14-10-2018 IPR007272 Sulphur transport domain D521_1465 5c70127ebfae888c26bc9a866aacd5ab 306 PRINTS PR01270 Histone deacetylase superfamily signature 156 171 1.6E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 D521_1465 5c70127ebfae888c26bc9a866aacd5ab 306 PRINTS PR01270 Histone deacetylase superfamily signature 233 243 1.6E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 D521_1465 5c70127ebfae888c26bc9a866aacd5ab 306 PRINTS PR01270 Histone deacetylase superfamily signature 122 145 1.6E-16 T 14-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 D521_1465 5c70127ebfae888c26bc9a866aacd5ab 306 Gene3D G3DSA:3.40.800.20 1 306 1.4E-127 T 14-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 D521_1465 5c70127ebfae888c26bc9a866aacd5ab 306 Pfam PF00850 Histone deacetylase domain 20 303 2.0E-82 T 14-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 D521_1465 5c70127ebfae888c26bc9a866aacd5ab 306 SUPERFAMILY SSF52768 1 305 1.87E-109 T 14-10-2018 IPR023696 Ureohydrolase domain superfamily D521_0122 34ceb69433012d21a6ab1ca1a75453e4 466 SUPERFAMILY SSF81342 21 293 1.88E-94 T 14-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 D521_0122 34ceb69433012d21a6ab1ca1a75453e4 466 SUPERFAMILY SSF81648 294 453 1.28E-22 T 14-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 D521_0122 34ceb69433012d21a6ab1ca1a75453e4 466 PIRSF PIRSF038885 11 466 3.5E-149 T 14-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 D521_0122 34ceb69433012d21a6ab1ca1a75453e4 466 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 291 438 9.5E-42 T 14-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 D521_0122 34ceb69433012d21a6ab1ca1a75453e4 466 Pfam PF00033 Cytochrome b/b6/petB 37 225 2.1E-66 T 14-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 D521_0122 34ceb69433012d21a6ab1ca1a75453e4 466 Gene3D G3DSA:1.20.810.10 8 466 1.2E-155 T 14-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 D521_1082 cbb4c9e00ee26d81789c2c3443b6ad47 252 SUPERFAMILY SSF51261 49 251 6.8E-49 T 14-10-2018 IPR011055 Duplicated hybrid motif D521_1082 cbb4c9e00ee26d81789c2c3443b6ad47 252 Gene3D G3DSA:2.70.70.10 121 252 3.0E-37 T 14-10-2018 IPR011055 Duplicated hybrid motif D521_1082 cbb4c9e00ee26d81789c2c3443b6ad47 252 Gene3D G3DSA:3.10.350.10 41 103 3.6E-13 T 14-10-2018 IPR036779 LysM domain superfamily D521_1082 cbb4c9e00ee26d81789c2c3443b6ad47 252 SMART SM00257 49 93 3.5E-10 T 14-10-2018 IPR018392 LysM domain D521_1082 cbb4c9e00ee26d81789c2c3443b6ad47 252 Pfam PF01476 LysM domain 50 91 8.3E-11 T 14-10-2018 IPR018392 LysM domain D521_1082 cbb4c9e00ee26d81789c2c3443b6ad47 252 Pfam PF01551 Peptidase family M23 153 247 2.6E-32 T 14-10-2018 IPR016047 Peptidase M23 D521_0576 535585323572edee685f222deebf5073 643 Pfam PF00005 ABC transporter 332 465 2.8E-21 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0576 535585323572edee685f222deebf5073 643 SUPERFAMILY SSF52540 312 505 1.15E-43 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0576 535585323572edee685f222deebf5073 643 Gene3D G3DSA:3.40.50.300 9 276 2.0E-66 T 14-10-2018 D521_0576 535585323572edee685f222deebf5073 643 Gene3D G3DSA:1.10.287.380 560 642 3.1E-15 T 14-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 D521_0576 535585323572edee685f222deebf5073 643 SUPERFAMILY SSF52540 5 230 1.07E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0576 535585323572edee685f222deebf5073 643 Pfam PF16326 ABC transporter C-terminal domain 570 637 9.8E-15 T 14-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 D521_0576 535585323572edee685f222deebf5073 643 ProSitePatterns PS00211 ABC transporters family signature. 437 451 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0576 535585323572edee685f222deebf5073 643 Pfam PF00005 ABC transporter 19 182 3.7E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0576 535585323572edee685f222deebf5073 643 SMART SM00382 28 226 1.4E-13 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0576 535585323572edee685f222deebf5073 643 SMART SM00382 340 511 5.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0576 535585323572edee685f222deebf5073 643 Pfam PF12848 ABC transporter 221 294 3.3E-9 T 14-10-2018 IPR032781 ABC-transporter extension domain D521_0576 535585323572edee685f222deebf5073 643 Gene3D G3DSA:3.40.50.300 278 543 1.3E-61 T 14-10-2018 D521_0100 4acef7cb394d78a82fb7ea10ad01fe2b 56 Gene3D G3DSA:3.30.750.24 1 56 9.9E-6 T 14-10-2018 IPR036513 STAS domain superfamily D521_0100 4acef7cb394d78a82fb7ea10ad01fe2b 56 SUPERFAMILY SSF52091 1 54 1.96E-5 T 14-10-2018 IPR036513 STAS domain superfamily D521_0100 4acef7cb394d78a82fb7ea10ad01fe2b 56 Pfam PF13466 STAS domain 1 49 2.1E-9 T 14-10-2018 IPR002645 STAS domain D521_1364 0900c9f244ac75a39db57587eaf2411d 432 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 254 431 1.4E-87 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 D521_1364 0900c9f244ac75a39db57587eaf2411d 432 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 255 2.5E-105 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 D521_1364 0900c9f244ac75a39db57587eaf2411d 432 SUPERFAMILY SSF51621 8 431 6.73E-154 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 D521_1364 0900c9f244ac75a39db57587eaf2411d 432 PIRSF PIRSF001362 1 432 9.3E-225 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 D521_1364 0900c9f244ac75a39db57587eaf2411d 432 ProSitePatterns PS00161 Isocitrate lyase signature. 191 196 - T 14-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 D521_1364 0900c9f244ac75a39db57587eaf2411d 432 Gene3D G3DSA:3.20.20.60 2 414 1.4E-171 T 14-10-2018 D521_1364 0900c9f244ac75a39db57587eaf2411d 432 Pfam PF00463 Isocitrate lyase family 255 431 3.8E-49 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 D521_1364 0900c9f244ac75a39db57587eaf2411d 432 Pfam PF00463 Isocitrate lyase family 8 254 8.1E-59 T 14-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 889 0.0 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Pfam PF08264 Anticodon-binding domain of tRNA 726 853 2.9E-15 T 14-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 890 22.58 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 48 59 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 PRINTS PR00985 Leucyl-tRNA synthetase signature 159 175 2.2E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 PRINTS PR00985 Leucyl-tRNA synthetase signature 220 239 2.2E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 PRINTS PR00985 Leucyl-tRNA synthetase signature 510 528 2.2E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 PRINTS PR00985 Leucyl-tRNA synthetase signature 191 204 2.2E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 PRINTS PR00985 Leucyl-tRNA synthetase signature 580 590 2.2E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 PRINTS PR00985 Leucyl-tRNA synthetase signature 133 150 2.2E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 PRINTS PR00985 Leucyl-tRNA synthetase signature 547 569 2.2E-48 T 14-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Pfam PF09334 tRNA synthetases class I (M) 44 177 4.3E-18 T 14-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 SUPERFAMILY SSF52374 5 693 6.81E-142 T 14-10-2018 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Gene3D G3DSA:3.90.740.10 232 432 0.0 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 SUPERFAMILY SSF50677 234 433 1.15E-49 T 14-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 SUPERFAMILY SSF47323 688 889 1.55E-29 T 14-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Gene3D G3DSA:3.10.20.590 831 890 1.3E-20 T 14-10-2018 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 226 421 3.8E-64 T 14-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Gene3D G3DSA:3.10.330.110 590 654 0.0 T 14-10-2018 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 435 595 6.3E-8 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 644 684 8.7E-7 T 14-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Gene3D G3DSA:1.10.730.10 8 822 0.0 T 14-10-2018 D521_0235 6a90ccb24d0876c296b03514de0427fb 890 Gene3D G3DSA:3.40.50.620 39 589 0.0 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1551 f764db2f495b0395091b9417236a617a 182 Pfam PF16036 Chalcone isomerase-like 25 170 2.7E-16 T 14-10-2018 IPR016087 Chalcone isomerase GO:0016872 D521_1551 f764db2f495b0395091b9417236a617a 182 Gene3D G3DSA:3.50.70.10 18 154 7.0E-7 T 14-10-2018 IPR016088 Chalcone isomerase, 3-layer sandwich KEGG: 00941+5.5.1.6|MetaCyc: PWY-2002|MetaCyc: PWY-5059|MetaCyc: PWY-6325|MetaCyc: PWY-6787|MetaCyc: PWY-7397|MetaCyc: PWY-7897 D521_1072 61f9810de1986db017cef7edb69f74fb 454 PIRSF PIRSF006485 1 444 5.2E-166 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 D521_1072 61f9810de1986db017cef7edb69f74fb 454 Gene3D G3DSA:3.40.50.300 176 349 2.4E-48 T 14-10-2018 D521_1072 61f9810de1986db017cef7edb69f74fb 454 Hamap MF_00195 GTPase Der [der]. 2 439 36.848 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 D521_1072 61f9810de1986db017cef7edb69f74fb 454 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 157 1.0E-18 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 D521_1072 61f9810de1986db017cef7edb69f74fb 454 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 180 345 3.4E-28 T 14-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 D521_1072 61f9810de1986db017cef7edb69f74fb 454 SUPERFAMILY SSF52540 4 163 5.24E-40 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1072 61f9810de1986db017cef7edb69f74fb 454 Gene3D G3DSA:3.40.50.300 5 164 2.3E-38 T 14-10-2018 D521_1072 61f9810de1986db017cef7edb69f74fb 454 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 91 1.9E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_1072 61f9810de1986db017cef7edb69f74fb 454 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.9E-7 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_1072 61f9810de1986db017cef7edb69f74fb 454 SUPERFAMILY SSF52540 138 442 3.21E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1072 61f9810de1986db017cef7edb69f74fb 454 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 435 1.8E-166 T 14-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 D521_1072 61f9810de1986db017cef7edb69f74fb 454 Pfam PF01926 50S ribosome-binding GTPase 5 120 5.7E-24 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_1072 61f9810de1986db017cef7edb69f74fb 454 Pfam PF01926 50S ribosome-binding GTPase 182 300 7.0E-25 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_1072 61f9810de1986db017cef7edb69f74fb 454 Gene3D G3DSA:3.30.300.20 356 438 1.1E-18 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta D521_1072 61f9810de1986db017cef7edb69f74fb 454 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 356 435 5.9E-23 T 14-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like D521_0242 9d51e33b2a3fafc17e97dc7a80a83084 430 Gene3D G3DSA:3.40.640.10 69 322 9.6E-173 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0242 9d51e33b2a3fafc17e97dc7a80a83084 430 Pfam PF00202 Aminotransferase class-III 32 400 2.7E-76 T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_0242 9d51e33b2a3fafc17e97dc7a80a83084 430 SUPERFAMILY SSF53383 4 430 1.37E-128 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0242 9d51e33b2a3fafc17e97dc7a80a83084 430 Gene3D G3DSA:3.90.1150.10 7 423 9.6E-173 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_0242 9d51e33b2a3fafc17e97dc7a80a83084 430 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 429 1.4E-184 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 D521_0242 9d51e33b2a3fafc17e97dc7a80a83084 430 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 275 - T 14-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 D521_0242 9d51e33b2a3fafc17e97dc7a80a83084 430 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 430 100.567 T 14-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 D521_1121 28d50d24f2fed7e10b8fb756934c1e5d 337 PRINTS PR00412 Epoxide hydrolase signature 99 114 9.4E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_1121 28d50d24f2fed7e10b8fb756934c1e5d 337 PRINTS PR00412 Epoxide hydrolase signature 157 170 9.4E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_1121 28d50d24f2fed7e10b8fb756934c1e5d 337 PRINTS PR00412 Epoxide hydrolase signature 310 332 9.4E-8 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_1121 28d50d24f2fed7e10b8fb756934c1e5d 337 PRINTS PR00111 Alpha/beta hydrolase fold signature 157 170 3.9E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1121 28d50d24f2fed7e10b8fb756934c1e5d 337 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 114 3.9E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1121 28d50d24f2fed7e10b8fb756934c1e5d 337 PRINTS PR00111 Alpha/beta hydrolase fold signature 143 156 3.9E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1121 28d50d24f2fed7e10b8fb756934c1e5d 337 SUPERFAMILY SSF53474 41 334 2.08E-58 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1121 28d50d24f2fed7e10b8fb756934c1e5d 337 Pfam PF00561 alpha/beta hydrolase fold 73 274 3.4E-22 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1121 28d50d24f2fed7e10b8fb756934c1e5d 337 Gene3D G3DSA:3.40.50.1820 28 335 9.3E-75 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1049 c717d3b601f8d2e166c0af77d3b09d1d 342 SUPERFAMILY SSF50974 33 337 5.49E-64 T 14-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 D521_1049 c717d3b601f8d2e166c0af77d3b09d1d 342 Gene3D G3DSA:2.130.10.10 155 249 1.5E-16 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 D521_1049 c717d3b601f8d2e166c0af77d3b09d1d 342 Gene3D G3DSA:2.130.10.10 250 340 3.1E-16 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 D521_1049 c717d3b601f8d2e166c0af77d3b09d1d 342 Gene3D G3DSA:2.130.10.10 33 154 6.5E-19 T 14-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 D521_1049 c717d3b601f8d2e166c0af77d3b09d1d 342 Pfam PF02239 Cytochrome D1 heme domain 51 337 1.9E-11 T 14-10-2018 D521_1810 eb44a796b03d033bf7aee5feb91c4d7c 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 328 3.2E-95 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 D521_1810 eb44a796b03d033bf7aee5feb91c4d7c 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 328 4.1E-101 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 D521_1810 eb44a796b03d033bf7aee5feb91c4d7c 354 PIRSF PIRSF001359 1 329 3.0E-84 T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 D521_1810 eb44a796b03d033bf7aee5feb91c4d7c 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 1.7E-182 T 14-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 D521_1810 eb44a796b03d033bf7aee5feb91c4d7c 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 D521_1810 eb44a796b03d033bf7aee5feb91c4d7c 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 14-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 D521_1810 eb44a796b03d033bf7aee5feb91c4d7c 354 Gene3D G3DSA:3.20.20.70 1 354 8.0E-148 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1810 eb44a796b03d033bf7aee5feb91c4d7c 354 SUPERFAMILY SSF51569 1 329 2.64E-105 T 14-10-2018 D521_2097 6cda574b02a13adbd8b84caa19f3f642 183 Gene3D G3DSA:3.40.630.30 11 148 3.9E-21 T 14-10-2018 D521_2097 6cda574b02a13adbd8b84caa19f3f642 183 Pfam PF00583 Acetyltransferase (GNAT) family 44 132 1.1E-12 T 14-10-2018 IPR000182 GNAT domain D521_2097 6cda574b02a13adbd8b84caa19f3f642 183 SUPERFAMILY SSF55729 30 135 1.03E-19 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 PRINTS PR00127 Clp protease catalytic subunit P signature 183 202 9.4E-54 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 PRINTS PR00127 Clp protease catalytic subunit P signature 34 49 9.4E-54 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 PRINTS PR00127 Clp protease catalytic subunit P signature 126 145 9.4E-54 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 PRINTS PR00127 Clp protease catalytic subunit P signature 105 122 9.4E-54 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 PRINTS PR00127 Clp protease catalytic subunit P signature 74 94 9.4E-54 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 Pfam PF00574 Clp protease 28 207 1.7E-89 T 14-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 Gene3D G3DSA:3.90.226.10 6 209 1.2E-87 T 14-10-2018 D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 105 116 - T 14-10-2018 IPR018215 ClpP, Ser active site D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 127 140 - T 14-10-2018 IPR033135 ClpP, histidine active site D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 SUPERFAMILY SSF52096 27 207 1.69E-76 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 18 208 45.178 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 D521_0930 11bcda652916e1e04dcfe73ebba825ef 209 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 17 207 3.5E-106 T 14-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 D521_1755 7479a90d1938b6a368f2513d8db9f770 301 Gene3D G3DSA:3.40.50.10330 33 294 4.3E-90 T 14-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 D521_1755 7479a90d1938b6a368f2513d8db9f770 301 SUPERFAMILY SSF111331 15 296 2.75E-85 T 14-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily D521_1755 7479a90d1938b6a368f2513d8db9f770 301 Gene3D G3DSA:2.60.200.30 136 271 4.3E-90 T 14-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 D521_1755 7479a90d1938b6a368f2513d8db9f770 301 Pfam PF01513 ATP-NAD kinase 16 274 8.0E-64 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 D521_1755 7479a90d1938b6a368f2513d8db9f770 301 Hamap MF_00361 NAD kinase [nadK]. 14 294 31.761 T 14-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 D521_1571 ecac05e2bd13b23f2e3441cb36165483 229 Pfam PF01227 GTP cyclohydrolase I 47 226 7.8E-53 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 D521_1571 ecac05e2bd13b23f2e3441cb36165483 229 SUPERFAMILY SSF55620 11 227 8.15E-63 T 14-10-2018 D521_1571 ecac05e2bd13b23f2e3441cb36165483 229 Gene3D G3DSA:1.10.286.10 14 92 1.7E-8 T 14-10-2018 D521_1571 ecac05e2bd13b23f2e3441cb36165483 229 Gene3D G3DSA:3.30.1130.10 93 229 2.0E-41 T 14-10-2018 D521_1820 34a96c227fefd6b9c9fece50339879ae 327 Gene3D G3DSA:1.10.443.10 161 327 1.4E-33 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 D521_1820 34a96c227fefd6b9c9fece50339879ae 327 Gene3D G3DSA:1.10.150.130 52 160 5.9E-6 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal D521_1820 34a96c227fefd6b9c9fece50339879ae 327 Pfam PF00589 Phage integrase family 163 318 3.0E-24 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 D521_1820 34a96c227fefd6b9c9fece50339879ae 327 SUPERFAMILY SSF56349 59 325 5.59E-55 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_0221 6a0c6682bb2273619d1986fe645daf2d 246 SUPERFAMILY SSF53955 54 232 4.5E-48 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily D521_0221 6a0c6682bb2273619d1986fe645daf2d 246 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 6 235 2.7E-71 T 14-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0221 6a0c6682bb2273619d1986fe645daf2d 246 Pfam PF00912 Transglycosylase 57 232 5.8E-51 T 14-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0221 6a0c6682bb2273619d1986fe645daf2d 246 Gene3D G3DSA:1.10.3810.10 52 240 5.9E-48 T 14-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_1982 6ab18c6cdc0b6d7fca361387c870f27e 334 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 10 332 4.4E-135 T 14-10-2018 IPR014188 Acrylyl-CoA reductase AcuI D521_1982 6ab18c6cdc0b6d7fca361387c870f27e 334 Gene3D G3DSA:3.40.50.720 133 300 5.2E-120 T 14-10-2018 D521_1982 6ab18c6cdc0b6d7fca361387c870f27e 334 SUPERFAMILY SSF51735 126 293 1.01E-36 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1982 6ab18c6cdc0b6d7fca361387c870f27e 334 SUPERFAMILY SSF50129 9 152 3.96E-44 T 14-10-2018 IPR011032 GroES-like superfamily D521_1982 6ab18c6cdc0b6d7fca361387c870f27e 334 Pfam PF00107 Zinc-binding dehydrogenase 166 278 1.9E-15 T 14-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 D521_1982 6ab18c6cdc0b6d7fca361387c870f27e 334 Gene3D G3DSA:3.90.180.10 24 330 5.2E-120 T 14-10-2018 D521_1982 6ab18c6cdc0b6d7fca361387c870f27e 334 SMART SM00829 22 330 1.2E-4 T 14-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 D521_1439 04c79c658055d319737757e6fcb77a91 370 SUPERFAMILY SSF102114 33 323 1.7E-76 T 14-10-2018 D521_1439 04c79c658055d319737757e6fcb77a91 370 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 32 370 4.6E-114 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1439 04c79c658055d319737757e6fcb77a91 370 Pfam PF04055 Radical SAM superfamily 44 212 2.0E-29 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 D521_1439 04c79c658055d319737757e6fcb77a91 370 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 46 57 - T 14-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1439 04c79c658055d319737757e6fcb77a91 370 Gene3D G3DSA:3.20.20.70 29 370 1.7E-99 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1439 04c79c658055d319737757e6fcb77a91 370 Pfam PF06463 Molybdenum Cofactor Synthesis C 221 347 3.1E-36 T 14-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1439 04c79c658055d319737757e6fcb77a91 370 SMART SM00729 40 253 1.1E-10 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 D521_1439 04c79c658055d319737757e6fcb77a91 370 Pfam PF13394 4Fe-4S single cluster domain 47 139 2.5E-11 T 14-10-2018 D521_1439 04c79c658055d319737757e6fcb77a91 370 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 31 370 40.106 T 14-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_0969 e6737ce817b6bb54372d49d537cbbb09 236 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 14 216 1.8E-30 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 D521_0969 e6737ce817b6bb54372d49d537cbbb09 236 Hamap MF_02088 Probable queuosine precursor transporter. 5 222 16.234 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 D521_0969 e6737ce817b6bb54372d49d537cbbb09 236 Pfam PF02592 Putative vitamin uptake transporter 48 210 6.8E-47 T 14-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 D521_1339 09a0e1ec9d52e8f8439c11214f1c735a 119 PIRSF PIRSF000178 10 119 2.2E-10 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1339 09a0e1ec9d52e8f8439c11214f1c735a 119 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 11 109 1.7E-13 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1339 09a0e1ec9d52e8f8439c11214f1c735a 119 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 12 114 2.6E-17 T 14-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1339 09a0e1ec9d52e8f8439c11214f1c735a 119 SUPERFAMILY SSF81343 12 117 4.8E-18 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1339 09a0e1ec9d52e8f8439c11214f1c735a 119 Gene3D G3DSA:1.20.1300.10 3 118 4.8E-14 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_0535 74d9509f3d7d6ff2c278401c09c10ebd 730 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 225 331 6.2E-8 T 14-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 D521_0535 74d9509f3d7d6ff2c278401c09c10ebd 730 Gene3D G3DSA:3.40.1190.10 485 721 2.0E-16 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0535 74d9509f3d7d6ff2c278401c09c10ebd 730 SUPERFAMILY SSF56059 225 494 2.19E-33 T 14-10-2018 D521_0535 74d9509f3d7d6ff2c278401c09c10ebd 730 SMART SM01209 224 359 0.0011 T 14-10-2018 D521_0535 74d9509f3d7d6ff2c278401c09c10ebd 730 TIGRFAM TIGR02068 cya_phycin_syn: cyanophycin synthetase 11 727 4.0E-265 T 14-10-2018 IPR011810 Cyanophycin synthetase GO:0005524|GO:0009059|GO:0016874 MetaCyc: PWY-7052 D521_0535 74d9509f3d7d6ff2c278401c09c10ebd 730 Gene3D G3DSA:3.30.1490.20 225 315 3.2E-20 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 D521_0535 74d9509f3d7d6ff2c278401c09c10ebd 730 Gene3D G3DSA:3.30.470.20 385 479 6.9E-6 T 14-10-2018 D521_0535 74d9509f3d7d6ff2c278401c09c10ebd 730 SUPERFAMILY SSF53623 487 720 1.04E-16 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0066 2c9f078104c9a68e81ca5b3361862f0d 131 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 131 31.23 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0066 2c9f078104c9a68e81ca5b3361862f0d 131 Gene3D G3DSA:3.30.1370.30 2 73 1.8E-27 T 14-10-2018 D521_0066 2c9f078104c9a68e81ca5b3361862f0d 131 Pfam PF00410 Ribosomal protein S8 5 130 5.2E-49 T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0066 2c9f078104c9a68e81ca5b3361862f0d 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 14-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0066 2c9f078104c9a68e81ca5b3361862f0d 131 Gene3D G3DSA:3.30.1490.10 74 131 2.0E-24 T 14-10-2018 D521_0066 2c9f078104c9a68e81ca5b3361862f0d 131 SUPERFAMILY SSF56047 3 130 3.01E-47 T 14-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_1950 0405bbf3808eff4b4c9ff11496db13a2 89 SUPERFAMILY SSF55594 1 87 4.06E-28 T 14-10-2018 IPR035895 HPr-like superfamily D521_1950 0405bbf3808eff4b4c9ff11496db13a2 89 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 6.3E-31 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like D521_1950 0405bbf3808eff4b4c9ff11496db13a2 89 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 14-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site D521_1950 0405bbf3808eff4b4c9ff11496db13a2 89 PRINTS PR00107 Phosphocarrier protein signature 38 53 3.4E-14 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like D521_1950 0405bbf3808eff4b4c9ff11496db13a2 89 PRINTS PR00107 Phosphocarrier protein signature 53 70 3.4E-14 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like D521_1950 0405bbf3808eff4b4c9ff11496db13a2 89 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.4E-14 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like D521_1950 0405bbf3808eff4b4c9ff11496db13a2 89 Gene3D G3DSA:3.30.1340.10 1 88 3.6E-30 T 14-10-2018 IPR035895 HPr-like superfamily D521_1950 0405bbf3808eff4b4c9ff11496db13a2 89 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 14-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site D521_1950 0405bbf3808eff4b4c9ff11496db13a2 89 Pfam PF00381 PTS HPr component phosphorylation site 5 82 3.4E-25 T 14-10-2018 IPR000032 Phosphocarrier protein HPr-like D521_0877 9122e0dedf859098a68266829e8e4268 557 ProSitePatterns PS00455 Putative AMP-binding domain signature. 212 223 - T 14-10-2018 IPR020845 AMP-binding, conserved site D521_0877 9122e0dedf859098a68266829e8e4268 557 Gene3D G3DSA:3.30.300.310 462 557 3.6E-30 T 14-10-2018 D521_0877 9122e0dedf859098a68266829e8e4268 557 Pfam PF13193 AMP-binding enzyme C-terminal domain 474 548 3.7E-19 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain D521_0877 9122e0dedf859098a68266829e8e4268 557 SUPERFAMILY SSF56801 26 556 5.36E-143 T 14-10-2018 D521_0877 9122e0dedf859098a68266829e8e4268 557 Gene3D G3DSA:3.40.50.12780 15 461 4.1E-111 T 14-10-2018 D521_0877 9122e0dedf859098a68266829e8e4268 557 Pfam PF00501 AMP-binding enzyme 34 465 7.2E-101 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 Gene3D G3DSA:3.30.590.10 107 459 1.6E-145 T 14-10-2018 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 470 2.0E-199 T 14-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 388 400 - T 14-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 SUPERFAMILY SSF54368 4 101 3.53E-34 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 SMART SM01230 104 381 1.7E-143 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 Gene3D G3DSA:3.10.20.70 4 106 1.4E-36 T 14-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 14-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 14-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 Pfam PF00120 Glutamine synthetase, catalytic domain 105 468 4.0E-137 T 14-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 SUPERFAMILY SSF55931 104 470 3.14E-137 T 14-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 D521_1044 e48a58d2982f0ed38d31e06b75976d8e 471 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 97 1.7E-29 T 14-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 D521_0377 552366de7001d756584739b6570142e1 256 Pfam PF00106 short chain dehydrogenase 4 193 1.8E-50 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0377 552366de7001d756584739b6570142e1 256 SUPERFAMILY SSF51735 4 233 2.84E-58 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0377 552366de7001d756584739b6570142e1 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.2E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0377 552366de7001d756584739b6570142e1 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.2E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0377 552366de7001d756584739b6570142e1 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.2E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0377 552366de7001d756584739b6570142e1 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.2E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0377 552366de7001d756584739b6570142e1 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.2E-17 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0377 552366de7001d756584739b6570142e1 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0377 552366de7001d756584739b6570142e1 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 3.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0377 552366de7001d756584739b6570142e1 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.6E-7 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0377 552366de7001d756584739b6570142e1 256 Gene3D G3DSA:3.40.50.720 5 241 1.8E-61 T 14-10-2018 D521_0377 552366de7001d756584739b6570142e1 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 D521_1166 822cfd3a214695ae8a297f9780a33833 798 SUPERFAMILY SSF54665 16 173 1.26E-37 T 14-10-2018 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily D521_1166 822cfd3a214695ae8a297f9780a33833 798 SUPERFAMILY SSF56003 143 796 1.83E-181 T 14-10-2018 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily GO:0016491|GO:0055114 D521_1166 822cfd3a214695ae8a297f9780a33833 798 Gene3D G3DSA:3.30.365.10 391 773 5.8E-117 T 14-10-2018 D521_1166 822cfd3a214695ae8a297f9780a33833 798 SMART SM01008 36 151 6.9E-37 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead D521_1166 822cfd3a214695ae8a297f9780a33833 798 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 37 151 1.7E-22 T 14-10-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead D521_1166 822cfd3a214695ae8a297f9780a33833 798 Gene3D G3DSA:3.90.1170.50 11 151 6.3E-38 T 14-10-2018 D521_1166 822cfd3a214695ae8a297f9780a33833 798 Gene3D G3DSA:3.30.365.10 207 303 4.3E-60 T 14-10-2018 D521_1166 822cfd3a214695ae8a297f9780a33833 798 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 167 733 1.8E-150 T 14-10-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 D521_1166 822cfd3a214695ae8a297f9780a33833 798 Gene3D G3DSA:3.30.365.10 477 648 5.8E-117 T 14-10-2018 D521_1166 822cfd3a214695ae8a297f9780a33833 798 Gene3D G3DSA:3.30.365.10 165 381 4.3E-60 T 14-10-2018 D521_1940 28c9009fc4ad89cbf9c56c583453d5c6 253 SUPERFAMILY SSF53271 64 243 1.35E-23 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like D521_1940 28c9009fc4ad89cbf9c56c583453d5c6 253 Pfam PF00156 Phosphoribosyl transferase domain 189 244 3.9E-6 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 D521_1940 28c9009fc4ad89cbf9c56c583453d5c6 253 Gene3D G3DSA:3.40.50.2020 114 251 1.5E-11 T 14-10-2018 D521_1246 a5de9dbd38680e89753617eef6aed26b 274 Gene3D G3DSA:3.40.1280.10 126 274 6.5E-39 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal D521_1246 a5de9dbd38680e89753617eef6aed26b 274 SUPERFAMILY SSF55315 5 113 3.53E-8 T 14-10-2018 IPR029064 50S ribosomal protein L30e-like D521_1246 a5de9dbd38680e89753617eef6aed26b 274 SUPERFAMILY SSF75217 127 272 3.2E-32 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases D521_1246 a5de9dbd38680e89753617eef6aed26b 274 Pfam PF00588 SpoU rRNA Methylase family 129 266 2.0E-29 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 D521_0873 38e4f24e6b38a184e524322a221a8ca3 123 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 9 120 3.3E-18 T 14-10-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III D521_1735 994f20fdf441d7ca33820977b871c85a 409 Hamap MF_00005 Argininosuccinate synthase [argG]. 4 405 51.819 T 14-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 D521_1735 994f20fdf441d7ca33820977b871c85a 409 TIGRFAM TIGR00032 argG: argininosuccinate synthase 6 401 8.2E-142 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 D521_1735 994f20fdf441d7ca33820977b871c85a 409 SUPERFAMILY SSF52402 5 174 1.76E-46 T 14-10-2018 D521_1735 994f20fdf441d7ca33820977b871c85a 409 SUPERFAMILY SSF69864 180 403 9.29E-93 T 14-10-2018 D521_1735 994f20fdf441d7ca33820977b871c85a 409 Gene3D G3DSA:3.40.50.620 5 177 3.8E-66 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1735 994f20fdf441d7ca33820977b871c85a 409 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 10 18 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 D521_1735 994f20fdf441d7ca33820977b871c85a 409 Pfam PF00764 Arginosuccinate synthase 8 400 9.2E-153 T 14-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 D521_1735 994f20fdf441d7ca33820977b871c85a 409 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 120 131 - T 14-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 D521_1735 994f20fdf441d7ca33820977b871c85a 409 Gene3D G3DSA:3.90.1260.10 181 409 1.1E-97 T 14-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 D521_1692 b8546488cd5c634a1cfdb9e8448556df 281 Gene3D G3DSA:3.10.270.10 18 280 1.6E-90 T 14-10-2018 D521_1692 b8546488cd5c634a1cfdb9e8448556df 281 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 160 276 3.7E-30 T 14-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 D521_1692 b8546488cd5c634a1cfdb9e8448556df 281 Pfam PF02649 Type I GTP cyclohydrolase folE2 20 275 1.1E-86 T 14-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 D521_1692 b8546488cd5c634a1cfdb9e8448556df 281 Hamap MF_01527_B GTP cyclohydrolase FolE2 [folE2]. 20 280 35.049 T 14-10-2018 IPR022838 GTP cyclohydrolase FolE2 GO:0003934|GO:0035998 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 D521_0710 8168797bf8e59623ba7038fa281d300a 480 SMART SM00387 368 479 8.8E-23 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_0710 8168797bf8e59623ba7038fa281d300a 480 SUPERFAMILY SSF55874 324 476 4.58E-33 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0710 8168797bf8e59623ba7038fa281d300a 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 457 1.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_0710 8168797bf8e59623ba7038fa281d300a 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 423 1.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_0710 8168797bf8e59623ba7038fa281d300a 480 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 476 1.2E-10 T 14-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 D521_0710 8168797bf8e59623ba7038fa281d300a 480 Gene3D G3DSA:3.30.565.10 328 479 8.7E-34 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0710 8168797bf8e59623ba7038fa281d300a 480 SUPERFAMILY SSF47384 254 321 8.83E-8 T 14-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 D521_0710 8168797bf8e59623ba7038fa281d300a 480 Pfam PF00512 His Kinase A (phospho-acceptor) domain 259 321 8.6E-9 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_0710 8168797bf8e59623ba7038fa281d300a 480 SMART SM00388 257 327 2.8E-5 T 14-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 D521_0710 8168797bf8e59623ba7038fa281d300a 480 Gene3D G3DSA:1.10.287.130 233 322 8.6E-13 T 14-10-2018 D521_0710 8168797bf8e59623ba7038fa281d300a 480 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 371 476 2.4E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_0402 08c35e32b05cce7df58eedb585669fc5 224 SUPERFAMILY SSF53335 7 177 1.0E-30 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0402 08c35e32b05cce7df58eedb585669fc5 224 Gene3D G3DSA:3.40.50.150 9 211 4.6E-43 T 14-10-2018 D521_0402 08c35e32b05cce7df58eedb585669fc5 224 Pfam PF13649 Methyltransferase domain 43 136 2.9E-14 T 14-10-2018 D521_1181 209616bc343c0587cfd6e111e2d162ee 250 Gene3D G3DSA:3.60.10.10 8 249 2.5E-38 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily D521_1181 209616bc343c0587cfd6e111e2d162ee 250 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 32 240 2.6E-14 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase D521_1181 209616bc343c0587cfd6e111e2d162ee 250 SUPERFAMILY SSF56219 7 249 6.94E-38 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 Gene3D G3DSA:3.30.420.40 13 332 1.4E-129 T 14-10-2018 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 SUPERFAMILY SSF53067 155 338 2.27E-48 T 14-10-2018 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 Gene3D G3DSA:3.90.640.10 191 264 1.4E-129 T 14-10-2018 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 340 2.5E-154 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 Gene3D G3DSA:3.30.420.40 159 322 1.4E-129 T 14-10-2018 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 SUPERFAMILY SSF53067 9 153 4.15E-37 T 14-10-2018 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 4.5E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 4.5E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 4.5E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 4.5E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 4.5E-63 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 D521_2023 55021ada575f5d157ce202b91aa0fb6b 347 Pfam PF06723 MreB/Mbl protein 10 340 2.3E-148 T 14-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 D521_1578 fbcc899cd6e8509b81852d0c6dda5813 931 SUPERFAMILY SSF51621 13 931 6.59E-292 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 D521_1578 fbcc899cd6e8509b81852d0c6dda5813 931 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 4 931 18.947 T 14-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 D521_1578 fbcc899cd6e8509b81852d0c6dda5813 931 Pfam PF00311 Phosphoenolpyruvate carboxylase 138 931 8.0E-283 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 D521_1578 fbcc899cd6e8509b81852d0c6dda5813 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 409 429 4.2E-42 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 D521_1578 fbcc899cd6e8509b81852d0c6dda5813 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 258 273 4.2E-42 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 D521_1578 fbcc899cd6e8509b81852d0c6dda5813 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 140 153 4.2E-42 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 D521_1578 fbcc899cd6e8509b81852d0c6dda5813 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 754 780 4.2E-42 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 D521_1578 fbcc899cd6e8509b81852d0c6dda5813 931 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 621 650 4.2E-42 T 14-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 D521_1578 fbcc899cd6e8509b81852d0c6dda5813 931 Gene3D G3DSA:1.20.1440.90 287 412 1.5E-12 T 14-10-2018 D521_1578 fbcc899cd6e8509b81852d0c6dda5813 931 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 577 589 - T 14-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 D521_1566 f1c75147ee70900a5788f1521b571f79 836 SUPERFAMILY SSF81660 305 475 1.46E-18 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 Gene3D G3DSA:3.40.50.1000 292 608 2.1E-151 T 14-10-2018 IPR023214 HAD superfamily D521_1566 f1c75147ee70900a5788f1521b571f79 836 Pfam PF00690 Cation transporter/ATPase, N-terminus 4 53 6.6E-8 T 14-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 Pfam PF00689 Cation transporting ATPase, C-terminus 652 822 2.6E-29 T 14-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 SUPERFAMILY SSF56784 294 651 3.4E-55 T 14-10-2018 IPR036412 HAD-like superfamily D521_1566 f1c75147ee70900a5788f1521b571f79 836 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 297 303 - T 14-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 540 556 6.8E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 600 625 6.8E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 568 584 6.8E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 426 444 6.8E-18 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 SUPERFAMILY SSF81665 5 824 2.75E-89 T 14-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 SUPERFAMILY SSF81653 97 193 2.88E-26 T 14-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 68 317 1.4E-36 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 539 650 1.8E-31 T 14-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 Gene3D G3DSA:3.40.1110.10 305 475 2.1E-151 T 14-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 D521_1566 f1c75147ee70900a5788f1521b571f79 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 568 587 2.9E-39 T 14-10-2018 D521_1566 f1c75147ee70900a5788f1521b571f79 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 145 159 2.9E-39 T 14-10-2018 D521_1566 f1c75147ee70900a5788f1521b571f79 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 295 309 2.9E-39 T 14-10-2018 D521_1566 f1c75147ee70900a5788f1521b571f79 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 490 500 2.9E-39 T 14-10-2018 D521_1566 f1c75147ee70900a5788f1521b571f79 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 468 479 2.9E-39 T 14-10-2018 D521_1566 f1c75147ee70900a5788f1521b571f79 836 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 592 604 2.9E-39 T 14-10-2018 D521_1566 f1c75147ee70900a5788f1521b571f79 836 Pfam PF00702 haloacid dehalogenase-like hydrolase 291 581 1.6E-26 T 14-10-2018 D521_1566 f1c75147ee70900a5788f1521b571f79 836 Pfam PF00122 E1-E2 ATPase 95 275 7.9E-45 T 14-10-2018 D521_1566 f1c75147ee70900a5788f1521b571f79 836 Gene3D G3DSA:1.20.1110.10 22 720 2.1E-151 T 14-10-2018 D521_1566 f1c75147ee70900a5788f1521b571f79 836 Gene3D G3DSA:2.70.150.10 4 197 2.1E-151 T 14-10-2018 D521_0682 665352de8b50390d827681b49f55d2ad 821 SUPERFAMILY SSF56235 52 812 1.31E-211 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_0682 665352de8b50390d827681b49f55d2ad 821 Gene3D G3DSA:2.30.120.10 345 421 2.0E-163 T 14-10-2018 D521_0682 665352de8b50390d827681b49f55d2ad 821 Gene3D G3DSA:1.10.439.10 29 189 3.6E-48 T 14-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 D521_0682 665352de8b50390d827681b49f55d2ad 821 Gene3D G3DSA:1.10.1400.10 574 705 2.0E-163 T 14-10-2018 D521_0682 665352de8b50390d827681b49f55d2ad 821 PIRSF PIRSF001227 16 821 2.7E-170 T 14-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 D521_0682 665352de8b50390d827681b49f55d2ad 821 Gene3D G3DSA:3.60.20.10 273 798 2.0E-163 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_0682 665352de8b50390d827681b49f55d2ad 821 Pfam PF01804 Penicillin amidase 55 810 5.1E-206 T 14-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 D521_0892 56a2344221b5dedc9c4b1672920c32a0 279 SUPERFAMILY SSF55811 103 261 8.12E-27 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 D521_0892 56a2344221b5dedc9c4b1672920c32a0 279 Pfam PF00293 NUDIX domain 142 253 2.4E-14 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 D521_0892 56a2344221b5dedc9c4b1672920c32a0 279 Gene3D G3DSA:3.90.79.10 130 275 4.7E-55 T 14-10-2018 D521_0892 56a2344221b5dedc9c4b1672920c32a0 279 Gene3D G3DSA:3.30.750.160 39 215 4.7E-55 T 14-10-2018 D521_1657 c445dabe77a7e66269763974d783b5f2 86 Gene3D G3DSA:3.30.70.100 3 64 2.3E-18 T 14-10-2018 D521_1657 c445dabe77a7e66269763974d783b5f2 86 Pfam PF00403 Heavy-metal-associated domain 6 45 1.9E-12 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 D521_1657 c445dabe77a7e66269763974d783b5f2 86 SUPERFAMILY SSF55008 1 66 1.44E-16 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 D521_1657 c445dabe77a7e66269763974d783b5f2 86 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 SUPERFAMILY SSF53067 7 196 3.74E-60 T 14-10-2018 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 Gene3D G3DSA:3.30.420.40 12 370 6.8E-121 T 14-10-2018 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 376 2.4E-143 T 14-10-2018 IPR020823 Cell division protein FtsA D521_0174 c0c207daac511fe9f6757123c9e59d39 409 SUPERFAMILY SSF53067 197 376 6.74E-48 T 14-10-2018 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 SMART SM00842 9 195 2.6E-98 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 Pfam PF02491 SHS2 domain inserted in FTSA 84 161 1.4E-30 T 14-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 Gene3D G3DSA:3.30.1490.110 86 168 6.8E-121 T 14-10-2018 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 Gene3D G3DSA:3.30.420.40 196 351 6.8E-121 T 14-10-2018 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 Pfam PF14450 Cell division protein FtsA 206 373 9.2E-26 T 14-10-2018 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 Gene3D G3DSA:3.90.640.10 234 299 6.8E-121 T 14-10-2018 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 Pfam PF14450 Cell division protein FtsA 10 193 1.6E-11 T 14-10-2018 D521_0174 c0c207daac511fe9f6757123c9e59d39 409 PIRSF PIRSF003101 1 409 1.2E-148 T 14-10-2018 IPR020823 Cell division protein FtsA D521_0174 c0c207daac511fe9f6757123c9e59d39 409 Hamap MF_02033 Cell division protein FtsA [ftsA]. 5 409 30.946 T 14-10-2018 IPR020823 Cell division protein FtsA D521_0762 55ac4b328f94853aff0df541e28c0cca 250 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 29 249 1.7E-41 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF D521_0762 55ac4b328f94853aff0df541e28c0cca 250 Gene3D G3DSA:3.40.190.10 29 233 7.4E-62 T 14-10-2018 D521_0762 55ac4b328f94853aff0df541e28c0cca 250 SUPERFAMILY SSF53850 1 249 8.18E-53 T 14-10-2018 D521_0762 55ac4b328f94853aff0df541e28c0cca 250 Gene3D G3DSA:3.40.190.10 114 212 7.4E-62 T 14-10-2018 D521_0762 55ac4b328f94853aff0df541e28c0cca 250 SMART SM00062 28 250 2.8E-35 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF D521_1198 8b52da28cb2df0bf5048d3a8fe50d61c 64 ProSitePatterns PS01047 Heavy-metal-associated domain. 6 35 - T 14-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 D521_1198 8b52da28cb2df0bf5048d3a8fe50d61c 64 SUPERFAMILY SSF55008 2 62 8.77E-16 T 14-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 D521_1198 8b52da28cb2df0bf5048d3a8fe50d61c 64 Pfam PF00403 Heavy-metal-associated domain 3 55 1.7E-9 T 14-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 D521_1198 8b52da28cb2df0bf5048d3a8fe50d61c 64 Gene3D G3DSA:3.30.70.100 1 62 2.1E-18 T 14-10-2018 D521_1373 8e17feb02b232135d38c1aa71660e655 200 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 2 190 7.2E-20 T 14-10-2018 IPR003111 Lon, substrate-binding domain D521_1373 8e17feb02b232135d38c1aa71660e655 200 SUPERFAMILY SSF88697 1 190 4.97E-40 T 14-10-2018 IPR015947 PUA-like superfamily D521_1373 8e17feb02b232135d38c1aa71660e655 200 SMART SM00464 2 191 7.1E-6 T 14-10-2018 IPR003111 Lon, substrate-binding domain D521_1373 8e17feb02b232135d38c1aa71660e655 200 Gene3D G3DSA:1.10.4060.10 108 200 1.3E-23 T 14-10-2018 D521_1373 8e17feb02b232135d38c1aa71660e655 200 Gene3D G3DSA:2.30.130.40 1 107 2.1E-27 T 14-10-2018 D521_0131 3b2f148654baa17601406fd2e2603025 424 Pfam PF02646 RmuC family 114 410 4.8E-106 T 14-10-2018 IPR003798 DNA recombination RmuC D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 SUPERFAMILY SSF55904 603 750 1.01E-45 T 14-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 PIRSF PIRSF009393 1 750 1.9E-280 T 14-10-2018 IPR011193 Ornithine/lysine/arginine decarboxylase GO:0005737|GO:0006520|GO:0016831 D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 Gene3D G3DSA:3.40.640.10 151 456 1.1E-96 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 Gene3D G3DSA:3.90.1150.10 458 628 2.4E-69 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 Gene3D G3DSA:3.90.100.10 629 749 2.7E-40 T 14-10-2018 D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 609 733 1.8E-47 T 14-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 Pfam PF03709 Orn/Lys/Arg decarboxylase, N-terminal domain 20 145 2.8E-38 T 14-10-2018 IPR005308 Orn/Lys/Arg decarboxylase, N-terminal GO:0016831 D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 SUPERFAMILY SSF53383 151 601 5.97E-112 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 391 405 - T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 151 582 7.8E-151 T 14-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 D521_0517 5adcb90b627b2e37fb1a365ff389f9dc 755 Gene3D G3DSA:3.40.50.2300 5 150 2.5E-22 T 14-10-2018 D521_0401 842ba6edbdb8b194d1fc5eeade86349f 65 Gene3D G3DSA:1.10.8.1050 6 61 2.6E-9 T 14-10-2018 D521_0495 29e229eee96aae72c9acff01bd738549 434 Pfam PF17408 Malonyl-CoA decarboxylase N-terminal domain 61 143 1.4E-25 T 14-10-2018 IPR035372 Malonyl-CoA decarboxylase, N-terminal KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 D521_0495 29e229eee96aae72c9acff01bd738549 434 Gene3D G3DSA:1.20.140.90 13 144 2.4E-39 T 14-10-2018 IPR038351 Malonyl-CoA decarboxylase, N-terminal domain superfamily KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 D521_0495 29e229eee96aae72c9acff01bd738549 434 Pfam PF05292 Malonyl-CoA decarboxylase C-terminal domain 146 406 1.4E-96 T 14-10-2018 IPR007956 Malonyl-CoA decarboxylase, C-terminal GO:0006633|GO:0050080 KEGG: 00410+4.1.1.9|KEGG: 00640+4.1.1.9|Reactome: R-HSA-390247|Reactome: R-HSA-9033241 D521_0495 29e229eee96aae72c9acff01bd738549 434 Gene3D G3DSA:3.40.630.150 145 434 1.5E-99 T 14-10-2018 D521_0383 6063e990befd8615e408c402693d83bc 176 Gene3D G3DSA:3.40.630.30 13 173 3.4E-36 T 14-10-2018 D521_0383 6063e990befd8615e408c402693d83bc 176 Pfam PF00583 Acetyltransferase (GNAT) family 74 158 2.8E-10 T 14-10-2018 IPR000182 GNAT domain D521_0383 6063e990befd8615e408c402693d83bc 176 SUPERFAMILY SSF55729 19 163 8.58E-22 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 SUPERFAMILY SSF55681 166 514 6.45E-115 T 14-10-2018 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 Pfam PF00152 tRNA synthetases class II (D, K and N) 167 513 8.3E-81 T 14-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 Gene3D G3DSA:3.30.930.10 166 514 5.3E-127 T 14-10-2018 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 26 516 43.069 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 Pfam PF01336 OB-fold nucleic acid binding domain 73 150 1.6E-11 T 14-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 PRINTS PR00982 Lysyl-tRNA synthetase signature 219 235 1.8E-37 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 PRINTS PR00982 Lysyl-tRNA synthetase signature 398 414 1.8E-37 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 PRINTS PR00982 Lysyl-tRNA synthetase signature 248 261 1.8E-37 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 PRINTS PR00982 Lysyl-tRNA synthetase signature 203 213 1.8E-37 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 PRINTS PR00982 Lysyl-tRNA synthetase signature 266 283 1.8E-37 T 14-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 21 515 3.5E-195 T 14-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 SUPERFAMILY SSF50249 18 159 4.41E-41 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1323 671aadde4bfe2a400e3ff2c9bb745e28 518 Gene3D G3DSA:2.40.50.140 20 158 4.1E-39 T 14-10-2018 D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 SUPERFAMILY SSF50249 1 88 9.42E-41 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 Gene3D G3DSA:2.40.50.140 1 90 2.3E-47 T 14-10-2018 D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 PRINTS PR01034 Ribosomal protein S12 signature 41 58 8.1E-49 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 PRINTS PR01034 Ribosomal protein S12 signature 6 21 8.1E-49 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 PRINTS PR01034 Ribosomal protein S12 signature 58 74 8.1E-49 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 PRINTS PR01034 Ribosomal protein S12 signature 22 41 8.1E-49 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 PRINTS PR01034 Ribosomal protein S12 signature 74 86 8.1E-49 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 ProSitePatterns PS00055 Ribosomal protein S12 signature. 7 14 - T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 Pfam PF00164 Ribosomal protein S12/S23 1 87 1.7E-32 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 87 2.1E-51 T 14-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0047 aaafcc64d7c8d79a072661b8425e0b37 90 PIRSF PIRSF002133 1 88 4.0E-44 T 14-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0960 af0d3539f960cf845180068f1e71bc4d 488 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 1 474 39.81 T 14-10-2018 IPR003846 Uncharacterised protein family UPF0061 D521_0960 af0d3539f960cf845180068f1e71bc4d 488 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 7 457 2.1E-129 T 14-10-2018 IPR003846 Uncharacterised protein family UPF0061 D521_0771 4731066c9234875d9840c4dce3161404 1020 Gene3D G3DSA:3.30.70.1430 547 640 4.5E-288 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 SUPERFAMILY SSF82866 279 478 9.42E-47 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 SUPERFAMILY SSF82693 125 312 3.14E-21 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 Gene3D G3DSA:3.30.70.1430 28 790 4.5E-288 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 PRINTS PR00702 Acriflavin resistance protein family signature 345 366 8.4E-66 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0771 4731066c9234875d9840c4dce3161404 1020 PRINTS PR00702 Acriflavin resistance protein family signature 318 341 8.4E-66 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0771 4731066c9234875d9840c4dce3161404 1020 PRINTS PR00702 Acriflavin resistance protein family signature 532 549 8.4E-66 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0771 4731066c9234875d9840c4dce3161404 1020 PRINTS PR00702 Acriflavin resistance protein family signature 598 612 8.4E-66 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0771 4731066c9234875d9840c4dce3161404 1020 PRINTS PR00702 Acriflavin resistance protein family signature 426 449 8.4E-66 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0771 4731066c9234875d9840c4dce3161404 1020 PRINTS PR00702 Acriflavin resistance protein family signature 26 44 8.4E-66 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0771 4731066c9234875d9840c4dce3161404 1020 PRINTS PR00702 Acriflavin resistance protein family signature 373 397 8.4E-66 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0771 4731066c9234875d9840c4dce3161404 1020 PRINTS PR00702 Acriflavin resistance protein family signature 451 474 8.4E-66 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0771 4731066c9234875d9840c4dce3161404 1020 Gene3D G3DSA:3.30.70.1440 641 840 4.5E-288 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 Gene3D G3DSA:3.30.2090.10 693 782 4.5E-288 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0771 4731066c9234875d9840c4dce3161404 1020 SUPERFAMILY SSF82866 780 1004 4.45E-45 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 Gene3D G3DSA:3.30.70.1320 123 314 4.5E-288 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 Gene3D G3DSA:3.30.2090.10 167 257 4.5E-288 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0771 4731066c9234875d9840c4dce3161404 1020 SUPERFAMILY SSF82693 545 641 3.66E-13 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 SUPERFAMILY SSF82714 696 781 9.94E-14 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0771 4731066c9234875d9840c4dce3161404 1020 Gene3D G3DSA:1.20.1640.10 2 492 4.5E-288 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 Pfam PF00873 AcrB/AcrD/AcrF family 2 1001 1.3E-291 T 14-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 D521_0771 4731066c9234875d9840c4dce3161404 1020 SUPERFAMILY SSF82693 28 121 1.52E-20 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 Gene3D G3DSA:1.20.1640.10 493 998 4.5E-288 T 14-10-2018 D521_0771 4731066c9234875d9840c4dce3161404 1020 SUPERFAMILY SSF82714 171 254 5.36E-16 T 14-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains D521_0394 63cbdbf4ed35d1eb603987ff3c9606bf 107 Pfam PF00543 Nitrogen regulatory protein P-II 4 102 1.5E-21 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_0394 63cbdbf4ed35d1eb603987ff3c9606bf 107 SUPERFAMILY SSF54913 1 103 2.16E-23 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta D521_0394 63cbdbf4ed35d1eb603987ff3c9606bf 107 Gene3D G3DSA:3.30.70.120 1 107 5.6E-24 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal D521_0394 63cbdbf4ed35d1eb603987ff3c9606bf 107 SMART SM00938 4 105 7.5E-21 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_0394 63cbdbf4ed35d1eb603987ff3c9606bf 107 PRINTS PR00340 P-II protein signature 2 17 9.3E-14 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_0394 63cbdbf4ed35d1eb603987ff3c9606bf 107 PRINTS PR00340 P-II protein signature 52 75 9.3E-14 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_0394 63cbdbf4ed35d1eb603987ff3c9606bf 107 PRINTS PR00340 P-II protein signature 83 103 9.3E-14 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_1517 a00cf6f6c34553c0f2f942035c91d2a9 146 PRINTS PR01438 Universal stress protein signature 124 146 1.4E-14 T 14-10-2018 IPR006015 Universal stress protein A D521_1517 a00cf6f6c34553c0f2f942035c91d2a9 146 PRINTS PR01438 Universal stress protein signature 2 20 1.4E-14 T 14-10-2018 IPR006015 Universal stress protein A D521_1517 a00cf6f6c34553c0f2f942035c91d2a9 146 PRINTS PR01438 Universal stress protein signature 106 118 1.4E-14 T 14-10-2018 IPR006015 Universal stress protein A D521_1517 a00cf6f6c34553c0f2f942035c91d2a9 146 Gene3D G3DSA:3.40.50.620 1 146 8.0E-30 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1517 a00cf6f6c34553c0f2f942035c91d2a9 146 Pfam PF00582 Universal stress protein family 1 144 2.1E-28 T 14-10-2018 IPR006016 UspA D521_1517 a00cf6f6c34553c0f2f942035c91d2a9 146 SUPERFAMILY SSF52402 1 145 5.78E-30 T 14-10-2018 D521_1892 775a2b2329e381d79702ae68c5a90dd3 257 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 165 179 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 D521_1892 775a2b2329e381d79702ae68c5a90dd3 257 Pfam PF01209 ubiE/COQ5 methyltransferase family 26 256 4.8E-80 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 D521_1892 775a2b2329e381d79702ae68c5a90dd3 257 Gene3D G3DSA:3.40.50.150 36 257 3.9E-66 T 14-10-2018 D521_1892 775a2b2329e381d79702ae68c5a90dd3 257 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 21 256 36.569 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 D521_1892 775a2b2329e381d79702ae68c5a90dd3 257 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 41 56 - T 14-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 D521_1892 775a2b2329e381d79702ae68c5a90dd3 257 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 30 256 1.4E-76 T 14-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 D521_1892 775a2b2329e381d79702ae68c5a90dd3 257 SUPERFAMILY SSF53335 11 248 3.7E-43 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 SUPERFAMILY SSF53067 111 326 8.42E-41 T 14-10-2018 D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 351 61.436 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 ProSitePatterns PS01016 Glycoprotease family signature. 105 125 - T 14-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 323 1.4E-110 T 14-10-2018 IPR017861 Kae1/TsaD family D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 SUPERFAMILY SSF53067 3 129 6.47E-30 T 14-10-2018 D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 2.3E-51 T 14-10-2018 IPR017861 Kae1/TsaD family D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 106 125 2.3E-51 T 14-10-2018 IPR017861 Kae1/TsaD family D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 85 105 2.3E-51 T 14-10-2018 IPR017861 Kae1/TsaD family D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 163 184 2.3E-51 T 14-10-2018 IPR017861 Kae1/TsaD family D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 280 289 2.3E-51 T 14-10-2018 IPR017861 Kae1/TsaD family D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 140 152 2.3E-51 T 14-10-2018 IPR017861 Kae1/TsaD family D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 Pfam PF00814 Glycoprotease family 33 324 4.3E-98 T 14-10-2018 IPR000905 Gcp-like domain D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 330 4.8E-126 T 14-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 Gene3D G3DSA:3.30.420.40 3 330 1.4E-122 T 14-10-2018 D521_1691 24a9eafcfffba90c13abf9c46b9d5f8e 357 Gene3D G3DSA:3.30.420.40 138 310 1.4E-122 T 14-10-2018 D521_0092 b7684d439591f0e0b680869aaa69c80a 234 SMART SM01321 9 123 4.2E-47 T 14-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 D521_0092 b7684d439591f0e0b680869aaa69c80a 234 Gene3D G3DSA:3.30.70.1290 1 162 1.1E-38 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 D521_0092 b7684d439591f0e0b680869aaa69c80a 234 SUPERFAMILY SSF143422 3 126 7.19E-35 T 14-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 D521_0092 b7684d439591f0e0b680869aaa69c80a 234 Pfam PF01797 Transposase IS200 like 12 121 4.6E-19 T 14-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 D521_0307 b8ae389a0c346abb65ed4cef5a433c8b 516 Pfam PF01050 Mannose-6-phosphate isomerase 360 510 9.2E-73 T 14-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 D521_0307 b8ae389a0c346abb65ed4cef5a433c8b 516 Pfam PF00483 Nucleotidyl transferase 15 331 1.2E-49 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 D521_0307 b8ae389a0c346abb65ed4cef5a433c8b 516 SUPERFAMILY SSF53448 13 326 9.24E-52 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0307 b8ae389a0c346abb65ed4cef5a433c8b 516 Gene3D G3DSA:2.60.120.10 392 503 3.0E-20 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_0307 b8ae389a0c346abb65ed4cef5a433c8b 516 SUPERFAMILY SSF51182 222 514 7.86E-80 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily D521_0307 b8ae389a0c346abb65ed4cef5a433c8b 516 Gene3D G3DSA:3.90.550.10 14 391 3.1E-102 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0307 b8ae389a0c346abb65ed4cef5a433c8b 516 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 13 514 1.2E-184 T 14-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 D521_1415 02d414868e2ff3d4c64d397d209c946e 353 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 5 351 48.835 T 14-10-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 D521_1415 02d414868e2ff3d4c64d397d209c946e 353 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 246 263 - T 14-10-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 D521_1415 02d414868e2ff3d4c64d397d209c946e 353 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 14 317 2.0E-68 T 14-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 D521_1415 02d414868e2ff3d4c64d397d209c946e 353 Gene3D G3DSA:3.20.20.300 1 351 9.2E-113 T 14-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 D521_1415 02d414868e2ff3d4c64d397d209c946e 353 SUPERFAMILY SSF51445 5 304 8.42E-73 T 14-10-2018 IPR017853 Glycoside hydrolase superfamily D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 2.0E-92 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 2.0E-92 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 2.0E-92 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 2.0E-92 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 2.0E-92 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 2.0E-92 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 2.0E-92 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 2.0E-92 T 14-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 Pfam PF01578 Cytochrome C assembly protein 89 295 1.9E-53 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 1.3E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.3E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 1.3E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 621 634 1.3E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 1.3E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.3E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 1.3E-53 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 628 1.4E-127 T 14-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal D521_1538 99a5802075d0fd922a8b0a2b602d8fb1 639 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 631 2.6E-233 T 14-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 D521_1832 5c1407408582668440fbc57a235b6676 401 SMART SM00471 201 336 3.9E-5 T 14-10-2018 IPR003607 HD/PDEase domain D521_1832 5c1407408582668440fbc57a235b6676 401 SUPERFAMILY SSF109604 196 366 1.54E-37 T 14-10-2018 D521_1832 5c1407408582668440fbc57a235b6676 401 TIGRFAM TIGR00277 HDIG: HDIG domain 203 296 8.9E-9 T 14-10-2018 IPR006675 HDIG domain D521_1832 5c1407408582668440fbc57a235b6676 401 Gene3D G3DSA:1.10.3210.10 179 374 6.0E-65 T 14-10-2018 D521_1832 5c1407408582668440fbc57a235b6676 401 Pfam PF13487 HD domain 256 317 4.4E-19 T 14-10-2018 D521_0261 c4d3b1a445f7edc2de1a23790ef46d0a 490 Gene3D G3DSA:3.40.605.10 26 481 7.3E-182 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 D521_0261 c4d3b1a445f7edc2de1a23790ef46d0a 490 SUPERFAMILY SSF53720 12 489 5.5E-169 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 D521_0261 c4d3b1a445f7edc2de1a23790ef46d0a 490 Pfam PF00171 Aldehyde dehydrogenase family 26 486 3.7E-168 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 D521_0261 c4d3b1a445f7edc2de1a23790ef46d0a 490 TIGRFAM TIGR01780 SSADH: succinate-semialdehyde dehydrogenase 35 484 1.2E-213 T 14-10-2018 IPR010102 Succinate semialdehyde dehydrogenase GO:0009013|GO:0009450|GO:0055114 Reactome: R-HSA-916853 D521_0261 c4d3b1a445f7edc2de1a23790ef46d0a 490 Gene3D G3DSA:3.40.309.10 269 458 7.3E-182 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 D521_0261 c4d3b1a445f7edc2de1a23790ef46d0a 490 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 290 301 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 D521_0062 f0a772c172d7fff90b3dc51198eefe9d 122 SUPERFAMILY SSF50193 1 122 2.49E-49 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 D521_0062 f0a772c172d7fff90b3dc51198eefe9d 122 Gene3D G3DSA:2.40.150.20 1 122 5.8E-52 T 14-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 D521_0062 f0a772c172d7fff90b3dc51198eefe9d 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 4.4E-56 T 14-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 D521_0062 f0a772c172d7fff90b3dc51198eefe9d 122 SMART SM01374 1 122 1.5E-82 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 D521_0062 f0a772c172d7fff90b3dc51198eefe9d 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.013 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 D521_0062 f0a772c172d7fff90b3dc51198eefe9d 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 14-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0062 f0a772c172d7fff90b3dc51198eefe9d 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 4.1E-53 T 14-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 D521_1948 bae5721e425129bbe2152e50904682b6 250 SUPERFAMILY SSF69572 2 247 3.01E-82 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 D521_1948 bae5721e425129bbe2152e50904682b6 250 Pfam PF00899 ThiF family 9 243 2.8E-60 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 D521_1948 bae5721e425129bbe2152e50904682b6 250 Gene3D G3DSA:3.40.50.720 1 250 5.1E-85 T 14-10-2018 D521_1110 fce398fb09726b0dec588c09c95560e1 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 6.3E-40 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 D521_1110 fce398fb09726b0dec588c09c95560e1 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 D521_1110 fce398fb09726b0dec588c09c95560e1 108 Gene3D G3DSA:3.40.30.10 2 108 4.9E-37 T 14-10-2018 D521_1110 fce398fb09726b0dec588c09c95560e1 108 PIRSF PIRSF000077 2 108 6.2E-44 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 D521_1110 fce398fb09726b0dec588c09c95560e1 108 SUPERFAMILY SSF52833 3 108 1.06E-40 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1110 fce398fb09726b0dec588c09c95560e1 108 Pfam PF00085 Thioredoxin 5 107 5.6E-35 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 D521_1110 fce398fb09726b0dec588c09c95560e1 108 PRINTS PR00421 Thioredoxin family signature 72 83 4.5E-9 T 14-10-2018 D521_1110 fce398fb09726b0dec588c09c95560e1 108 PRINTS PR00421 Thioredoxin family signature 24 32 4.5E-9 T 14-10-2018 D521_1110 fce398fb09726b0dec588c09c95560e1 108 PRINTS PR00421 Thioredoxin family signature 32 41 4.5E-9 T 14-10-2018 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 Pfam PF00175 Oxidoreductase NAD-binding domain 213 318 7.7E-20 T 14-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 SUPERFAMILY SSF54292 2 89 8.65E-27 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 Pfam PF00970 Oxidoreductase FAD-binding domain 105 201 7.8E-15 T 14-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 196 205 1.1E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 304 312 1.1E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 237 246 1.1E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 212 231 1.1E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 1.1E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 1.1E-23 T 14-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 SUPERFAMILY SSF63380 102 203 1.43E-21 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 Gene3D G3DSA:3.40.50.80 204 339 5.1E-32 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 Gene3D G3DSA:2.40.30.10 102 203 1.1E-23 T 14-10-2018 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 Gene3D G3DSA:3.10.20.30 1 95 2.5E-26 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 SUPERFAMILY SSF52343 205 338 5.5E-37 T 14-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 148 155 9.6E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 212 231 9.6E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 237 246 9.6E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 304 312 9.6E-7 T 14-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 D521_1714 0afc586e948d2e3d0178f44cc31242ae 346 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 81 2.2E-15 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 D521_0055 952642821aec6a932eb1376673e4634d 276 SMART SM01383 42 119 6.5E-43 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0055 952642821aec6a932eb1376673e4634d 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 274 2.1E-124 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 D521_0055 952642821aec6a932eb1376673e4634d 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 274 45.255 T 14-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 D521_0055 952642821aec6a932eb1376673e4634d 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.0E-31 T 14-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0055 952642821aec6a932eb1376673e4634d 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 127 251 4.0E-53 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 D521_0055 952642821aec6a932eb1376673e4634d 276 Gene3D G3DSA:2.40.50.140 1 115 4.4E-44 T 14-10-2018 D521_0055 952642821aec6a932eb1376673e4634d 276 SMART SM01382 125 253 2.4E-86 T 14-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 D521_0055 952642821aec6a932eb1376673e4634d 276 SUPERFAMILY SSF50104 128 273 2.05E-58 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily D521_0055 952642821aec6a932eb1376673e4634d 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 14-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0055 952642821aec6a932eb1376673e4634d 276 Gene3D G3DSA:2.30.30.30 119 196 6.2E-30 T 14-10-2018 IPR014722 Ribosomal protein L2, domain 2 D521_0055 952642821aec6a932eb1376673e4634d 276 SUPERFAMILY SSF50249 3 126 1.51E-47 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_0055 952642821aec6a932eb1376673e4634d 276 PIRSF PIRSF002158 5 276 1.3E-96 T 14-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0055 952642821aec6a932eb1376673e4634d 276 Gene3D G3DSA:4.10.950.10 197 275 7.2E-36 T 14-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_1570 9f9c27e023cc8c752ee8d9545228fc2c 157 PRINTS PR01011 Glutathione peroxidase family signature 20 37 1.7E-20 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 D521_1570 9f9c27e023cc8c752ee8d9545228fc2c 157 PRINTS PR01011 Glutathione peroxidase family signature 55 71 1.7E-20 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 D521_1570 9f9c27e023cc8c752ee8d9545228fc2c 157 PRINTS PR01011 Glutathione peroxidase family signature 121 130 1.7E-20 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 D521_1570 9f9c27e023cc8c752ee8d9545228fc2c 157 Gene3D G3DSA:3.40.30.10 2 157 7.2E-64 T 14-10-2018 D521_1570 9f9c27e023cc8c752ee8d9545228fc2c 157 Pfam PF00255 Glutathione peroxidase 10 109 4.6E-39 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 D521_1570 9f9c27e023cc8c752ee8d9545228fc2c 157 SUPERFAMILY SSF52833 5 157 3.8E-56 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1570 9f9c27e023cc8c752ee8d9545228fc2c 157 PIRSF PIRSF000303 1 157 7.4E-59 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 D521_1570 9f9c27e023cc8c752ee8d9545228fc2c 157 ProSitePatterns PS00460 Glutathione peroxidases active site. 22 37 - T 14-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 D521_0713 3d5019f43fb896aada19c5286dc38f81 332 Gene3D G3DSA:3.40.190.10 133 256 1.6E-113 T 14-10-2018 D521_0713 3d5019f43fb896aada19c5286dc38f81 332 SUPERFAMILY SSF53850 120 294 7.27E-17 T 14-10-2018 D521_0713 3d5019f43fb896aada19c5286dc38f81 332 PIRSF PIRSF017082 3 332 7.9E-86 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0713 3d5019f43fb896aada19c5286dc38f81 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 328 8.5E-86 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0713 3d5019f43fb896aada19c5286dc38f81 332 Gene3D G3DSA:3.40.190.150 35 322 1.6E-113 T 14-10-2018 D521_0720 c2bf4da962733dcaa21d95adcaf0f043 67 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 55 1.1E-17 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0720 c2bf4da962733dcaa21d95adcaf0f043 67 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 60 15.43 T 14-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0720 c2bf4da962733dcaa21d95adcaf0f043 67 SUPERFAMILY SSF63562 1 63 3.31E-18 T 14-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 D521_0720 c2bf4da962733dcaa21d95adcaf0f043 67 Pfam PF01192 RNA polymerase Rpb6 8 56 1.1E-13 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 D521_0720 c2bf4da962733dcaa21d95adcaf0f043 67 SMART SM01409 8 59 3.4E-13 T 14-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 D521_0720 c2bf4da962733dcaa21d95adcaf0f043 67 Gene3D G3DSA:3.90.940.10 1 66 2.0E-19 T 14-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 D521_0914 af4bb88d31aed59e22ff4eb999b653e1 439 Gene3D G3DSA:1.20.1250.20 1 421 1.5E-19 T 14-10-2018 D521_0914 af4bb88d31aed59e22ff4eb999b653e1 439 Pfam PF07690 Major Facilitator Superfamily 9 360 2.9E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_0914 af4bb88d31aed59e22ff4eb999b653e1 439 SUPERFAMILY SSF103473 2 422 7.59E-22 T 14-10-2018 IPR036259 MFS transporter superfamily D521_1417 979193e55444658690435785dbc42675 247 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 8 240 4.0E-100 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 D521_1417 979193e55444658690435785dbc42675 247 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 245 119.592 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 D521_1417 979193e55444658690435785dbc42675 247 SUPERFAMILY SSF63892 7 243 7.59E-96 T 14-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 D521_1417 979193e55444658690435785dbc42675 247 Gene3D G3DSA:3.20.20.70 1 247 7.0E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1417 979193e55444658690435785dbc42675 247 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 9 241 2.0E-91 T 14-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 D521_1111 b214833b324fd75a3f53e26e4ff65053 420 Gene3D G3DSA:1.10.720.10 1 47 4.0E-18 T 14-10-2018 D521_1111 b214833b324fd75a3f53e26e4ff65053 420 Gene3D G3DSA:2.40.50.140 48 123 2.5E-32 T 14-10-2018 D521_1111 b214833b324fd75a3f53e26e4ff65053 420 SMART SM00959 5 47 6.4E-16 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 D521_1111 b214833b324fd75a3f53e26e4ff65053 420 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 238.436 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 D521_1111 b214833b324fd75a3f53e26e4ff65053 420 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 5.1E-207 T 14-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 D521_1111 b214833b324fd75a3f53e26e4ff65053 420 SUPERFAMILY SSF50249 49 125 5.25E-28 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1111 b214833b324fd75a3f53e26e4ff65053 420 SUPERFAMILY SSF68912 1 46 3.73E-11 T 14-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily D521_1111 b214833b324fd75a3f53e26e4ff65053 420 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 1.1E-14 T 14-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 D521_1111 b214833b324fd75a3f53e26e4ff65053 420 SUPERFAMILY SSF52540 90 371 2.22E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1111 b214833b324fd75a3f53e26e4ff65053 420 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 8.7E-24 T 14-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_1111 b214833b324fd75a3f53e26e4ff65053 420 SMART SM00357 52 118 5.5E-17 T 14-10-2018 IPR011129 Cold shock domain GO:0003676 D521_1111 b214833b324fd75a3f53e26e4ff65053 420 Gene3D G3DSA:3.40.50.300 130 417 2.1E-126 T 14-10-2018 D521_1111 b214833b324fd75a3f53e26e4ff65053 420 SMART SM00382 170 349 7.0E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1111 b214833b324fd75a3f53e26e4ff65053 420 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 2.5E-30 T 14-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 D521_0925 58a0dd4f5cb143e3a2e53d595b1b1def 274 Gene3D G3DSA:3.90.550.10 29 272 1.1E-62 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0925 58a0dd4f5cb143e3a2e53d595b1b1def 274 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 36 268 8.5E-52 T 14-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 D521_0925 58a0dd4f5cb143e3a2e53d595b1b1def 274 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 137 144 - T 14-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 D521_0925 58a0dd4f5cb143e3a2e53d595b1b1def 274 SUPERFAMILY SSF53448 35 268 1.44E-48 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0925 58a0dd4f5cb143e3a2e53d595b1b1def 274 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 37 268 1.1E-56 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 D521_0925 58a0dd4f5cb143e3a2e53d595b1b1def 274 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 34 268 36.55 T 14-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 D521_0887 4052dc4d81f05b83791891d45c67b681 308 SUPERFAMILY SSF51391 108 306 1.83E-56 T 14-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 D521_0887 4052dc4d81f05b83791891d45c67b681 308 Pfam PF02581 Thiamine monophosphate synthase 121 289 7.0E-49 T 14-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 D521_0887 4052dc4d81f05b83791891d45c67b681 308 Gene3D G3DSA:3.20.20.70 108 307 1.8E-51 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 SUPERFAMILY SSF55874 1 195 9.95E-50 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 9 149 8.3E-16 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR00418 DNA topoisomerase II family signature 512 524 6.7E-60 T 14-10-2018 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR00418 DNA topoisomerase II family signature 88 102 6.7E-60 T 14-10-2018 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR00418 DNA topoisomerase II family signature 564 580 6.7E-60 T 14-10-2018 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR00418 DNA topoisomerase II family signature 257 270 6.7E-60 T 14-10-2018 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR00418 DNA topoisomerase II family signature 492 509 6.7E-60 T 14-10-2018 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR00418 DNA topoisomerase II family signature 7 22 6.7E-60 T 14-10-2018 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR00418 DNA topoisomerase II family signature 474 490 6.7E-60 T 14-10-2018 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR00418 DNA topoisomerase II family signature 42 55 6.7E-60 T 14-10-2018 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR00418 DNA topoisomerase II family signature 405 419 6.7E-60 T 14-10-2018 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 Gene3D G3DSA:3.30.230.10 197 380 1.3E-43 T 14-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 SUPERFAMILY SSF54211 198 378 1.67E-35 T 14-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 560 624 5.1E-23 T 14-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 Gene3D G3DSA:3.40.50.670 381 627 1.4E-81 T 14-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 ProSitePatterns PS00177 DNA topoisomerase II signature. 407 415 - T 14-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 Pfam PF00204 DNA gyrase B 217 376 4.0E-32 T 14-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 Pfam PF01751 Toprim domain 404 518 7.9E-12 T 14-10-2018 IPR006171 TOPRIM domain D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 SMART SM00433 9 628 7.6E-188 T 14-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 SMART SM00387 3 153 3.2E-17 T 14-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 Gene3D G3DSA:3.30.565.10 1 196 4.2E-58 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR01098 Topoisomerase IV subunit B signature 2 15 1.5E-29 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR01098 Topoisomerase IV subunit B signature 154 171 1.5E-29 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR01098 Topoisomerase IV subunit B signature 353 378 1.5E-29 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR01098 Topoisomerase IV subunit B signature 439 460 1.5E-29 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR01098 Topoisomerase IV subunit B signature 114 128 1.5E-29 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR01098 Topoisomerase IV subunit B signature 172 193 1.5E-29 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 PRINTS PR01098 Topoisomerase IV subunit B signature 329 352 1.5E-29 T 14-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 D521_0896 d8f585b77df77e2bf1364a81babb4f8f 634 SUPERFAMILY SSF56719 379 626 1.52E-73 T 14-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 D521_1426 3ee8b3791a9d540fdc581f37b090e2cb 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 14-10-2018 IPR006162 Phosphopantetheine attachment site D521_1426 3ee8b3791a9d540fdc581f37b090e2cb 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.164 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 D521_1426 3ee8b3791a9d540fdc581f37b090e2cb 79 Gene3D G3DSA:1.10.1200.10 1 79 7.3E-29 T 14-10-2018 IPR036736 ACP-like superfamily D521_1426 3ee8b3791a9d540fdc581f37b090e2cb 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 3.0E-10 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 D521_1426 3ee8b3791a9d540fdc581f37b090e2cb 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 9.2E-35 T 14-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 D521_1426 3ee8b3791a9d540fdc581f37b090e2cb 79 Pfam PF00550 Phosphopantetheine attachment site 6 67 9.6E-17 T 14-10-2018 IPR009081 Phosphopantetheine binding ACP domain D521_1426 3ee8b3791a9d540fdc581f37b090e2cb 79 SMART SM00823 Phosphopantetheine attachment site 5 63 0.0039 T 14-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 D521_1426 3ee8b3791a9d540fdc581f37b090e2cb 79 SUPERFAMILY SSF47336 2 76 1.16E-22 T 14-10-2018 IPR036736 ACP-like superfamily D521_1968 a1f6a7a8fe2e8ffbc6a54eedb0bf2ead 192 Pfam PF00255 Glutathione peroxidase 45 142 9.2E-36 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 D521_1968 a1f6a7a8fe2e8ffbc6a54eedb0bf2ead 192 Gene3D G3DSA:3.40.30.10 20 192 2.5E-56 T 14-10-2018 D521_1968 a1f6a7a8fe2e8ffbc6a54eedb0bf2ead 192 PRINTS PR01011 Glutathione peroxidase family signature 150 159 5.2E-17 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 D521_1968 a1f6a7a8fe2e8ffbc6a54eedb0bf2ead 192 PRINTS PR01011 Glutathione peroxidase family signature 54 71 5.2E-17 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 D521_1968 a1f6a7a8fe2e8ffbc6a54eedb0bf2ead 192 PRINTS PR01011 Glutathione peroxidase family signature 89 105 5.2E-17 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 D521_1968 a1f6a7a8fe2e8ffbc6a54eedb0bf2ead 192 PIRSF PIRSF000303 12 192 2.3E-63 T 14-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 D521_1968 a1f6a7a8fe2e8ffbc6a54eedb0bf2ead 192 ProSitePatterns PS00460 Glutathione peroxidases active site. 56 71 - T 14-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 D521_1968 a1f6a7a8fe2e8ffbc6a54eedb0bf2ead 192 SUPERFAMILY SSF52833 35 188 4.81E-54 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0624 230dd1a5b084bad7e925c7f839bc99a7 141 SUPERFAMILY SSF52402 1 141 7.12E-30 T 14-10-2018 D521_0624 230dd1a5b084bad7e925c7f839bc99a7 141 PRINTS PR01438 Universal stress protein signature 101 113 1.0E-10 T 14-10-2018 IPR006015 Universal stress protein A D521_0624 230dd1a5b084bad7e925c7f839bc99a7 141 PRINTS PR01438 Universal stress protein signature 119 141 1.0E-10 T 14-10-2018 IPR006015 Universal stress protein A D521_0624 230dd1a5b084bad7e925c7f839bc99a7 141 Gene3D G3DSA:3.40.50.620 1 141 2.5E-32 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0624 230dd1a5b084bad7e925c7f839bc99a7 141 Pfam PF00582 Universal stress protein family 2 141 6.1E-29 T 14-10-2018 IPR006016 UspA D521_1352 9fa721e0139c62bde1ae18dea2f871b2 189 SUPERFAMILY SSF46785 2 136 6.63E-35 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1352 9fa721e0139c62bde1ae18dea2f871b2 189 Gene3D G3DSA:1.10.10.10 1 143 7.0E-49 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1352 9fa721e0139c62bde1ae18dea2f871b2 189 Pfam PF02082 Transcriptional regulator 1 83 2.6E-26 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type D521_1352 9fa721e0139c62bde1ae18dea2f871b2 189 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 135 7.7E-43 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type D521_1162 cd7cf50d9d59788514782e07557417d6 389 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 287 3.6E-49 T 14-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 D521_1162 cd7cf50d9d59788514782e07557417d6 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 6.9E-19 T 14-10-2018 D521_1162 cd7cf50d9d59788514782e07557417d6 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 6.9E-19 T 14-10-2018 D521_1162 cd7cf50d9d59788514782e07557417d6 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 6.9E-19 T 14-10-2018 D521_1162 cd7cf50d9d59788514782e07557417d6 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 6.9E-19 T 14-10-2018 D521_1162 cd7cf50d9d59788514782e07557417d6 389 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 6.9E-19 T 14-10-2018 D521_1162 cd7cf50d9d59788514782e07557417d6 389 Gene3D G3DSA:3.50.50.60 115 249 5.1E-81 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1162 cd7cf50d9d59788514782e07557417d6 389 Gene3D G3DSA:3.50.50.60 13 285 5.1E-81 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1162 cd7cf50d9d59788514782e07557417d6 389 Gene3D G3DSA:3.30.390.120 321 384 2.5E-22 T 14-10-2018 D521_1162 cd7cf50d9d59788514782e07557417d6 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 2.0E-11 T 14-10-2018 D521_1162 cd7cf50d9d59788514782e07557417d6 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 2.0E-11 T 14-10-2018 D521_1162 cd7cf50d9d59788514782e07557417d6 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 2.0E-11 T 14-10-2018 D521_1162 cd7cf50d9d59788514782e07557417d6 389 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 2.0E-11 T 14-10-2018 D521_1162 cd7cf50d9d59788514782e07557417d6 389 SUPERFAMILY SSF51905 11 310 9.34E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1713 e94171cead86a6a92919abb882bba3a8 295 Gene3D G3DSA:3.40.50.720 4 294 1.1E-70 T 14-10-2018 D521_1713 e94171cead86a6a92919abb882bba3a8 295 Pfam PF13460 NAD(P)H-binding 15 206 3.8E-11 T 14-10-2018 IPR016040 NAD(P)-binding domain D521_1713 e94171cead86a6a92919abb882bba3a8 295 SUPERFAMILY SSF51735 8 272 5.89E-34 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0982 7d5305bcbe8207a0f4e3a3216c27fcf5 102 SUPERFAMILY SSF81296 1 99 4.06E-30 T 14-10-2018 IPR014756 Immunoglobulin E-set D521_0982 7d5305bcbe8207a0f4e3a3216c27fcf5 102 Gene3D G3DSA:2.60.40.10 3 101 1.8E-32 T 14-10-2018 IPR013783 Immunoglobulin-like fold D521_0982 7d5305bcbe8207a0f4e3a3216c27fcf5 102 Pfam PF08770 Sulphur oxidation protein SoxZ 7 99 3.5E-34 T 14-10-2018 IPR014880 Sulphur oxidation protein SoxZ D521_0982 7d5305bcbe8207a0f4e3a3216c27fcf5 102 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 6 100 2.2E-35 T 14-10-2018 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ D521_0940 54d58ba80b489e7d223dad564e150a23 553 Pfam PF06418 CTP synthase N-terminus 3 270 1.4E-124 T 14-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 D521_0940 54d58ba80b489e7d223dad564e150a23 553 Hamap MF_01227 CTP synthase [pyrG]. 2 545 50.858 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 D521_0940 54d58ba80b489e7d223dad564e150a23 553 Pfam PF00117 Glutamine amidotransferase class-I 305 540 1.7E-56 T 14-10-2018 IPR017926 Glutamine amidotransferase D521_0940 54d58ba80b489e7d223dad564e150a23 553 SUPERFAMILY SSF52540 2 270 2.89E-119 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0940 54d58ba80b489e7d223dad564e150a23 553 Gene3D G3DSA:3.40.50.880 290 549 4.0E-102 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_0940 54d58ba80b489e7d223dad564e150a23 553 SUPERFAMILY SSF52317 292 541 2.21E-87 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_0940 54d58ba80b489e7d223dad564e150a23 553 Gene3D G3DSA:3.40.50.300 1 289 1.8E-130 T 14-10-2018 D521_0940 54d58ba80b489e7d223dad564e150a23 553 TIGRFAM TIGR00337 PyrG: CTP synthase 1 540 4.9E-239 T 14-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Pfam PF04563 RNA polymerase beta subunit 26 504 1.3E-37 T 14-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Gene3D G3DSA:3.90.1800.10 1276 1329 6.7E-11 T 14-10-2018 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Gene3D G3DSA:2.40.270.10 794 836 1.2E-6 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Gene3D G3DSA:2.40.270.10 1050 1266 6.3E-82 T 14-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Gene3D G3DSA:2.40.50.100 718 792 2.2E-29 T 14-10-2018 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Gene3D G3DSA:3.90.1100.10 446 630 1.4E-71 T 14-10-2018 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 SUPERFAMILY SSF64484 13 1364 0.0 T 14-10-2018 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Pfam PF04565 RNA polymerase Rpb2, domain 3 517 584 2.1E-31 T 14-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Pfam PF04561 RNA polymerase Rpb2, domain 2 353 458 6.7E-16 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Pfam PF04561 RNA polymerase Rpb2, domain 2 154 226 3.3E-7 T 14-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Pfam PF04560 RNA polymerase Rpb2, domain 7 1290 1364 1.8E-26 T 14-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Pfam PF10385 RNA polymerase beta subunit external 1 domain 595 660 2.1E-23 T 14-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Pfam PF00562 RNA polymerase Rpb2, domain 6 721 1288 3.5E-158 T 14-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Gene3D G3DSA:2.40.50.150 837 963 2.2E-43 T 14-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1366 12.19 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Gene3D G3DSA:3.90.1110.10 313 445 1.6E-33 T 14-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1080 1092 - T 14-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 9 1362 0.0 T 14-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Gene3D G3DSA:3.90.1100.10 19 174 2.4E-49 T 14-10-2018 D521_0044 cdcdaa3b8fd9bf3d8fcc0dc69f55f8c4 1366 Gene3D G3DSA:3.90.1100.10 647 717 1.1E-19 T 14-10-2018 D521_0935 da1241ff2555418c8281d7a71abb3168 226 SUPERFAMILY SSF52540 11 226 2.73E-65 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0935 da1241ff2555418c8281d7a71abb3168 226 Gene3D G3DSA:3.40.50.300 8 226 1.1E-67 T 14-10-2018 D521_0935 da1241ff2555418c8281d7a71abb3168 226 Pfam PF00005 ABC transporter 27 175 3.9E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0935 da1241ff2555418c8281d7a71abb3168 226 SMART SM00382 36 222 4.8E-16 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0935 da1241ff2555418c8281d7a71abb3168 226 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_1844 f52c8335c3062d4b764fbd879e8d0cc3 226 SUPERFAMILY SSF47616 84 214 1.85E-23 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily D521_1844 f52c8335c3062d4b764fbd879e8d0cc3 226 TIGRFAM TIGR01262 maiA: maleylacetoacetate isomerase 4 215 1.7E-76 T 14-10-2018 IPR005955 Glutathione S-transferases, class Zeta GO:0003824|GO:0005737|GO:0009072 Reactome: R-HSA-156590|Reactome: R-HSA-204174|Reactome: R-HSA-71182 D521_1844 f52c8335c3062d4b764fbd879e8d0cc3 226 Gene3D G3DSA:1.20.1050.10 91 218 6.8E-42 T 14-10-2018 D521_1844 f52c8335c3062d4b764fbd879e8d0cc3 226 SUPERFAMILY SSF52833 2 87 8.97E-21 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1844 f52c8335c3062d4b764fbd879e8d0cc3 226 Gene3D G3DSA:3.40.30.10 2 90 1.3E-22 T 14-10-2018 D521_1844 f52c8335c3062d4b764fbd879e8d0cc3 226 Pfam PF13417 Glutathione S-transferase, N-terminal domain 5 84 4.6E-15 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 D521_2056 47b37470ea70c9e8231d7f17737bbc0f 263 SUPERFAMILY SSF74653 74 180 1.28E-9 T 14-10-2018 D521_2056 47b37470ea70c9e8231d7f17737bbc0f 263 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 117 179 1.8E-7 T 14-10-2018 IPR006260 TonB/TolA, C-terminal D521_2056 47b37470ea70c9e8231d7f17737bbc0f 263 Gene3D G3DSA:3.30.1150.10 57 180 6.5E-6 T 14-10-2018 D521_0533 d3ab785bf24de0679c704f194080d68e 336 PIRSF PIRSF000904 5 336 5.8E-114 T 14-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 D521_0533 d3ab785bf24de0679c704f194080d68e 336 PIRSF PIRSF500210 5 336 1.0E-117 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 D521_0533 d3ab785bf24de0679c704f194080d68e 336 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 23 195 2.6E-52 T 14-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 D521_0533 d3ab785bf24de0679c704f194080d68e 336 SUPERFAMILY SSF56655 11 333 1.11E-103 T 14-10-2018 D521_0533 d3ab785bf24de0679c704f194080d68e 336 Gene3D G3DSA:3.30.540.10 3 196 2.6E-58 T 14-10-2018 D521_0533 d3ab785bf24de0679c704f194080d68e 336 Gene3D G3DSA:3.40.190.80 198 335 8.8E-51 T 14-10-2018 D521_0533 d3ab785bf24de0679c704f194080d68e 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 207 234 9.9E-55 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 D521_0533 d3ab785bf24de0679c704f194080d68e 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 150 173 9.9E-55 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 D521_0533 d3ab785bf24de0679c704f194080d68e 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 34 61 9.9E-55 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 D521_0533 d3ab785bf24de0679c704f194080d68e 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 181 204 9.9E-55 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 D521_0533 d3ab785bf24de0679c704f194080d68e 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 309 334 9.9E-55 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 D521_0533 d3ab785bf24de0679c704f194080d68e 336 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 71 97 9.9E-55 T 14-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 D521_0533 d3ab785bf24de0679c704f194080d68e 336 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 9 335 43.571 T 14-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 D521_0219 23de888b0460f954b49ab2d84d9f5a3e 286 Gene3D G3DSA:3.30.1150.10 108 275 1.1E-14 T 14-10-2018 D521_0219 23de888b0460f954b49ab2d84d9f5a3e 286 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 194 259 6.9E-7 T 14-10-2018 IPR006260 TonB/TolA, C-terminal D521_0219 23de888b0460f954b49ab2d84d9f5a3e 286 SUPERFAMILY SSF74653 163 278 6.15E-15 T 14-10-2018 D521_1234 7a08f05a346c5e73396ab5cbe2ae5b3b 275 Hamap MF_01062 Phosphoenolpyruvate synthase regulatory protein [ppsR]. 5 273 71.557 T 14-10-2018 IPR026530 Phosphoenolpyruvate synthase regulatory protein D521_1234 7a08f05a346c5e73396ab5cbe2ae5b3b 275 Pfam PF03618 Kinase/pyrophosphorylase 8 264 4.9E-80 T 14-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 Pfam PF00174 Oxidoreductase molybdopterin binding domain 63 224 4.0E-37 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 SUPERFAMILY SSF56524 21 283 2.35E-50 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 PRINTS PR00407 Eukaryotic molybdopterin domain signature 39 55 6.6E-21 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 PRINTS PR00407 Eukaryotic molybdopterin domain signature 332 344 6.6E-21 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 PRINTS PR00407 Eukaryotic molybdopterin domain signature 173 189 6.6E-21 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 PRINTS PR00407 Eukaryotic molybdopterin domain signature 94 105 6.6E-21 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 PRINTS PR00407 Eukaryotic molybdopterin domain signature 190 203 6.6E-21 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 PRINTS PR00407 Eukaryotic molybdopterin domain signature 206 219 6.6E-21 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 PRINTS PR00407 Eukaryotic molybdopterin domain signature 287 299 6.6E-21 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 247 363 1.3E-13 T 14-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 Gene3D G3DSA:3.90.420.10 3 251 5.3E-74 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 Gene3D G3DSA:2.60.40.650 252 367 9.4E-34 T 14-10-2018 D521_2067 51dd7b5dc9355eaa4971b7d856fff3e2 367 SUPERFAMILY SSF81296 250 364 9.8E-27 T 14-10-2018 IPR014756 Immunoglobulin E-set D521_1462 3aade80ece73d5823d330b6eceb81a3b 595 Gene3D G3DSA:2.40.110.10 161 290 6.4E-28 T 14-10-2018 D521_1462 3aade80ece73d5823d330b6eceb81a3b 595 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 469 589 2.2E-26 T 14-10-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain D521_1462 3aade80ece73d5823d330b6eceb81a3b 595 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 44 158 3.9E-12 T 14-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 D521_1462 3aade80ece73d5823d330b6eceb81a3b 595 SUPERFAMILY SSF56645 41 282 2.49E-56 T 14-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 D521_1462 3aade80ece73d5823d330b6eceb81a3b 595 SUPERFAMILY SSF47203 283 455 2.74E-45 T 14-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 D521_1462 3aade80ece73d5823d330b6eceb81a3b 595 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 272 1.6E-16 T 14-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 D521_1462 3aade80ece73d5823d330b6eceb81a3b 595 Gene3D G3DSA:1.10.540.10 37 160 5.3E-16 T 14-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 D521_1462 3aade80ece73d5823d330b6eceb81a3b 595 Gene3D G3DSA:1.20.140.10 291 454 1.8E-49 T 14-10-2018 D521_1462 3aade80ece73d5823d330b6eceb81a3b 595 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 285 450 1.5E-28 T 14-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 D521_1462 3aade80ece73d5823d330b6eceb81a3b 595 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 32 8.9E-9 T 14-10-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria D521_1673 0b94e09802fa3b8ab9663bf2a7a6514c 346 Pfam PF13437 HlyD family secretion protein 171 218 2.1E-7 T 14-10-2018 D521_1673 0b94e09802fa3b8ab9663bf2a7a6514c 346 Gene3D G3DSA:2.40.420.20 258 345 8.8E-10 T 14-10-2018 D521_1673 0b94e09802fa3b8ab9663bf2a7a6514c 346 Gene3D G3DSA:2.40.50.100 95 213 1.3E-12 T 14-10-2018 D521_1673 0b94e09802fa3b8ab9663bf2a7a6514c 346 SUPERFAMILY SSF111369 92 196 2.09E-6 T 14-10-2018 D521_2042 5b5c39d47fc08ddd5f926390f6955d79 215 SMART SM00855 5 161 6.3E-23 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 D521_2042 5b5c39d47fc08ddd5f926390f6955d79 215 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 202 7.0E-58 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 D521_2042 5b5c39d47fc08ddd5f926390f6955d79 215 SUPERFAMILY SSF53254 1 208 1.67E-60 T 14-10-2018 IPR029033 Histidine phosphatase superfamily D521_2042 5b5c39d47fc08ddd5f926390f6955d79 215 PIRSF PIRSF000709 1 189 1.3E-10 T 14-10-2018 D521_2042 5b5c39d47fc08ddd5f926390f6955d79 215 Gene3D G3DSA:3.40.50.1240 3 213 5.9E-58 T 14-10-2018 IPR029033 Histidine phosphatase superfamily D521_2042 5b5c39d47fc08ddd5f926390f6955d79 215 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 14-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 D521_0608 b92a35c449727b7618a3e924aee373cb 586 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 260 420 3.8E-51 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 D521_0608 b92a35c449727b7618a3e924aee373cb 586 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 294 308 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 D521_0608 b92a35c449727b7618a3e924aee373cb 586 Gene3D G3DSA:3.30.70.1560 318 408 3.1E-50 T 14-10-2018 D521_0608 b92a35c449727b7618a3e924aee373cb 586 SMART SM00363 193 253 5.3E-6 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0608 b92a35c449727b7618a3e924aee373cb 586 Gene3D G3DSA:3.10.290.10 187 248 7.7E-18 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 D521_0608 b92a35c449727b7618a3e924aee373cb 586 SUPERFAMILY SSF55174 195 284 2.8E-15 T 14-10-2018 D521_0608 b92a35c449727b7618a3e924aee373cb 586 Gene3D G3DSA:3.30.70.580 257 416 3.1E-50 T 14-10-2018 D521_0608 b92a35c449727b7618a3e924aee373cb 586 Pfam PF00849 RNA pseudouridylate synthase 256 389 4.4E-16 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0608 b92a35c449727b7618a3e924aee373cb 586 Pfam PF01479 S4 domain 194 238 4.1E-6 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0608 b92a35c449727b7618a3e924aee373cb 586 SUPERFAMILY SSF55120 255 419 8.63E-42 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0214 db8755567269b643df77edc296042ae1 149 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 7 146 5.0E-52 T 14-10-2018 D521_0214 db8755567269b643df77edc296042ae1 149 SUPERFAMILY SSF52304 6 148 2.22E-62 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 D521_0214 db8755567269b643df77edc296042ae1 149 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 7 145 4.4E-64 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 D521_0214 db8755567269b643df77edc296042ae1 149 Gene3D G3DSA:3.40.50.9100 1 149 3.5E-67 T 14-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 D521_0214 db8755567269b643df77edc296042ae1 149 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 149 72.729 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 D521_0214 db8755567269b643df77edc296042ae1 149 ProSitePatterns PS01029 Dehydroquinase class II signature. 10 27 - T 14-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 D521_0214 db8755567269b643df77edc296042ae1 149 PIRSF PIRSF001399 3 149 7.0E-62 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 D521_0214 db8755567269b643df77edc296042ae1 149 Pfam PF01220 Dehydroquinase class II 6 143 2.4E-62 T 14-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 D521_0508 ee8a7a0114da6649927ef47eb3ec5ee2 140 Gene3D G3DSA:3.30.450.20 2 135 2.7E-26 T 14-10-2018 D521_0508 ee8a7a0114da6649927ef47eb3ec5ee2 140 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 130 3.5E-21 T 14-10-2018 IPR000014 PAS domain D521_0508 ee8a7a0114da6649927ef47eb3ec5ee2 140 Pfam PF00989 PAS fold 7 119 1.2E-14 T 14-10-2018 IPR013767 PAS fold GO:0006355 D521_0508 ee8a7a0114da6649927ef47eb3ec5ee2 140 SMART SM00091 5 71 5.1E-10 T 14-10-2018 IPR000014 PAS domain D521_0508 ee8a7a0114da6649927ef47eb3ec5ee2 140 SUPERFAMILY SSF55785 16 132 6.81E-25 T 14-10-2018 IPR035965 PAS domain superfamily D521_0609 c792c58b292c3813e15dedbe079f96c2 163 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 1 156 17.795 T 14-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 D521_0609 c792c58b292c3813e15dedbe079f96c2 163 Gene3D G3DSA:3.30.300.70 2 73 1.7E-7 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily D521_0609 c792c58b292c3813e15dedbe079f96c2 163 Pfam PF17384 RimP C-terminal SH3 domain 80 155 6.7E-9 T 14-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal D521_0609 c792c58b292c3813e15dedbe079f96c2 163 SUPERFAMILY SSF75420 7 76 7.85E-11 T 14-10-2018 IPR035956 RimP, N-terminal domain superfamily D521_0609 c792c58b292c3813e15dedbe079f96c2 163 Pfam PF02576 RimP N-terminal domain 7 76 2.9E-12 T 14-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal D521_0609 c792c58b292c3813e15dedbe079f96c2 163 SUPERFAMILY SSF74942 77 155 1.7E-8 T 14-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily D521_0707 498b5dc19711075658a9cf29cb163953 127 Pfam PF09086 Domain of unknown function (DUF1924) 35 123 4.6E-37 T 14-10-2018 IPR015170 Protein of unknown function DUF1924 D521_0707 498b5dc19711075658a9cf29cb163953 127 Gene3D G3DSA:1.10.760.10 19 127 2.2E-42 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0707 498b5dc19711075658a9cf29cb163953 127 SUPERFAMILY SSF46626 34 125 6.1E-29 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1891 f2a4c9c1a25b24e46aa3275956914596 303 SMART SM00978 170 301 1.0E-38 T 14-10-2018 IPR007379 Tim44-like domain D521_1891 f2a4c9c1a25b24e46aa3275956914596 303 SUPERFAMILY SSF54427 180 301 3.07E-13 T 14-10-2018 IPR032710 NTF2-like domain superfamily D521_1891 f2a4c9c1a25b24e46aa3275956914596 303 Pfam PF04280 Tim44-like domain 180 300 2.3E-17 T 14-10-2018 IPR007379 Tim44-like domain D521_1891 f2a4c9c1a25b24e46aa3275956914596 303 Gene3D G3DSA:3.10.450.240 178 301 7.2E-6 T 14-10-2018 D521_0863 07e61f47a431c3929882479e397ffe63 274 SUPERFAMILY SSF48452 124 229 4.05E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0863 07e61f47a431c3929882479e397ffe63 274 SMART SM00028 182 215 0.0014 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0863 07e61f47a431c3929882479e397ffe63 274 SMART SM00028 148 181 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0863 07e61f47a431c3929882479e397ffe63 274 Gene3D G3DSA:1.25.40.10 120 264 4.6E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0863 07e61f47a431c3929882479e397ffe63 274 Pfam PF14559 Tetratricopeptide repeat 124 188 6.3E-7 T 14-10-2018 D521_1089 2f8ec5dba2a69eb0375e058529cc8736 94 Gene3D G3DSA:3.30.2310.20 1 94 7.0E-28 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily D521_1089 2f8ec5dba2a69eb0375e058529cc8736 94 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 3 93 1.2E-21 T 14-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family D521_1089 2f8ec5dba2a69eb0375e058529cc8736 94 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 2 93 7.3E-28 T 14-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin D521_1089 2f8ec5dba2a69eb0375e058529cc8736 94 PIRSF PIRSF006156 1 94 5.7E-26 T 14-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin D521_1089 2f8ec5dba2a69eb0375e058529cc8736 94 SUPERFAMILY SSF143011 1 93 1.82E-20 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily D521_0661 af4fb1bd3d358bca795d4b8117688164 1588 SUPERFAMILY SSF141072 335 442 7.72E-13 T 14-10-2018 IPR038081 CalX-like domain superfamily D521_0661 af4fb1bd3d358bca795d4b8117688164 1588 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 725 757 1.3E-4 T 14-10-2018 IPR001434 Domain of unknown function DUF11 D521_0661 af4fb1bd3d358bca795d4b8117688164 1588 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 580 612 8.9E-7 T 14-10-2018 IPR001434 Domain of unknown function DUF11 D521_0661 af4fb1bd3d358bca795d4b8117688164 1588 SUPERFAMILY SSF141072 448 552 2.62E-12 T 14-10-2018 IPR038081 CalX-like domain superfamily D521_0661 af4fb1bd3d358bca795d4b8117688164 1588 Gene3D G3DSA:2.60.40.2030 325 456 2.5E-6 T 14-10-2018 IPR038081 CalX-like domain superfamily D521_1764 5e711a67220ef132ea8dd9db929f18d3 381 SUPERFAMILY SSF56176 17 175 6.54E-27 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 D521_1764 5e711a67220ef132ea8dd9db929f18d3 381 Gene3D G3DSA:3.30.465.10 55 174 2.0E-28 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 D521_1764 5e711a67220ef132ea8dd9db929f18d3 381 SUPERFAMILY SSF55103 136 379 6.21E-9 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 D521_1764 5e711a67220ef132ea8dd9db929f18d3 381 Pfam PF01565 FAD binding domain 18 133 3.0E-17 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 D521_0773 9389c18739612dc4a3f6d4c922a67cfe 151 SUPERFAMILY SSF53098 8 147 1.26E-58 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_0773 9389c18739612dc4a3f6d4c922a67cfe 151 Hamap MF_00042 Ribonuclease H [rnhA]. 7 149 33.076 T 14-10-2018 IPR022892 Ribonuclease HI GO:0004523 D521_0773 9389c18739612dc4a3f6d4c922a67cfe 151 Pfam PF00075 RNase H 10 146 4.8E-51 T 14-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 D521_0773 9389c18739612dc4a3f6d4c922a67cfe 151 PIRSF PIRSF037839 3 129 1.1E-7 T 14-10-2018 IPR017290 Ribonuclease H, Bacteroides-type GO:0004523 D521_0773 9389c18739612dc4a3f6d4c922a67cfe 151 Gene3D G3DSA:3.30.420.10 5 149 1.4E-60 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_1184 1b64f2e3407454124529552ecf12e1e7 223 ProSitePatterns PS00211 ABC transporters family signature. 117 131 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_1184 1b64f2e3407454124529552ecf12e1e7 223 SUPERFAMILY SSF52540 2 211 4.42E-47 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1184 1b64f2e3407454124529552ecf12e1e7 223 Pfam PF00005 ABC transporter 21 145 8.4E-25 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_1184 1b64f2e3407454124529552ecf12e1e7 223 SMART SM00382 23 193 3.8E-5 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1184 1b64f2e3407454124529552ecf12e1e7 223 Gene3D G3DSA:3.40.50.300 1 219 9.5E-50 T 14-10-2018 D521_0981 e4e9847f33208c80ff94587855d39eda 271 SUPERFAMILY SSF46626 156 270 2.7E-31 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0981 e4e9847f33208c80ff94587855d39eda 271 Gene3D G3DSA:1.10.760.10 146 271 2.8E-34 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0981 e4e9847f33208c80ff94587855d39eda 271 Gene3D G3DSA:1.10.760.10 49 145 1.0E-23 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0981 e4e9847f33208c80ff94587855d39eda 271 SUPERFAMILY SSF46626 31 151 1.05E-21 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0981 e4e9847f33208c80ff94587855d39eda 271 PIRSF PIRSF038455 6 271 5.5E-67 T 14-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 D521_0981 e4e9847f33208c80ff94587855d39eda 271 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 46 271 1.6E-76 T 14-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 D521_0884 77a3c869df9adbd3360d45554ab82486 596 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 395 559 1.6E-31 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 D521_0884 77a3c869df9adbd3360d45554ab82486 596 TIGRFAM TIGR01504 glyox_carbo_lig: glyoxylate carboligase 2 594 0.0 T 14-10-2018 IPR006397 Glyoxylate carboligase GO:0009028|GO:0009436 KEGG: 00630+4.1.1.47 D521_0884 77a3c869df9adbd3360d45554ab82486 596 Gene3D G3DSA:3.40.50.970 2 171 2.7E-64 T 14-10-2018 D521_0884 77a3c869df9adbd3360d45554ab82486 596 Gene3D G3DSA:3.40.50.1220 187 358 1.5E-47 T 14-10-2018 D521_0884 77a3c869df9adbd3360d45554ab82486 596 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 193 327 3.4E-35 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 D521_0884 77a3c869df9adbd3360d45554ab82486 596 SUPERFAMILY SSF52467 161 348 5.01E-47 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily D521_0884 77a3c869df9adbd3360d45554ab82486 596 SUPERFAMILY SSF52518 3 185 2.49E-46 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0884 77a3c869df9adbd3360d45554ab82486 596 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 6.0E-51 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 D521_0884 77a3c869df9adbd3360d45554ab82486 596 Gene3D G3DSA:3.40.50.970 361 588 3.9E-59 T 14-10-2018 D521_0884 77a3c869df9adbd3360d45554ab82486 596 SUPERFAMILY SSF52518 371 571 1.79E-48 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_1224 f9de8160467b7034278138a8c25210b8 535 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 5 208 6.8E-68 T 14-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 D521_1224 f9de8160467b7034278138a8c25210b8 535 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 216 535 1.3E-146 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 D521_1224 f9de8160467b7034278138a8c25210b8 535 PRINTS PR00097 Anthranilate synthase component II signature 53 62 2.6E-5 T 14-10-2018 D521_1224 f9de8160467b7034278138a8c25210b8 535 PRINTS PR00097 Anthranilate synthase component II signature 180 193 2.6E-5 T 14-10-2018 D521_1224 f9de8160467b7034278138a8c25210b8 535 PRINTS PR00097 Anthranilate synthase component II signature 80 91 2.6E-5 T 14-10-2018 D521_1224 f9de8160467b7034278138a8c25210b8 535 SUPERFAMILY SSF54810 408 535 5.89E-47 T 14-10-2018 D521_1224 f9de8160467b7034278138a8c25210b8 535 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 1.2E-6 T 14-10-2018 D521_1224 f9de8160467b7034278138a8c25210b8 535 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 1.2E-6 T 14-10-2018 D521_1224 f9de8160467b7034278138a8c25210b8 535 PRINTS PR00096 Glutamine amidotransferase superfamily signature 180 193 1.2E-6 T 14-10-2018 D521_1224 f9de8160467b7034278138a8c25210b8 535 Gene3D G3DSA:3.40.50.880 4 209 1.3E-48 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_1224 f9de8160467b7034278138a8c25210b8 535 SUPERFAMILY SSF52317 2 240 2.38E-51 T 14-10-2018 IPR029062 Class I glutamine amidotransferase-like D521_1224 f9de8160467b7034278138a8c25210b8 535 Gene3D G3DSA:3.30.300.10 409 535 1.2E-50 T 14-10-2018 D521_1224 f9de8160467b7034278138a8c25210b8 535 Pfam PF02540 NAD synthase 221 297 6.1E-8 T 14-10-2018 IPR022310 NAD/GMP synthase D521_1224 f9de8160467b7034278138a8c25210b8 535 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 2 535 55.161 T 14-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 D521_1224 f9de8160467b7034278138a8c25210b8 535 Pfam PF00958 GMP synthase C terminal domain 444 534 9.0E-43 T 14-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 D521_1224 f9de8160467b7034278138a8c25210b8 535 Gene3D G3DSA:3.40.50.620 213 408 6.1E-76 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1224 f9de8160467b7034278138a8c25210b8 535 Pfam PF00117 Glutamine amidotransferase class-I 7 202 4.1E-36 T 14-10-2018 IPR017926 Glutamine amidotransferase D521_1224 f9de8160467b7034278138a8c25210b8 535 SUPERFAMILY SSF52402 200 421 2.12E-59 T 14-10-2018 D521_0827 d2f7b5bc63eb1fe85366c61411237a65 151 Pfam PF00571 CBS domain 71 124 4.6E-7 T 14-10-2018 IPR000644 CBS domain D521_0827 d2f7b5bc63eb1fe85366c61411237a65 151 Pfam PF00571 CBS domain 15 60 1.3E-7 T 14-10-2018 IPR000644 CBS domain D521_0827 d2f7b5bc63eb1fe85366c61411237a65 151 SMART SM00116 78 125 3.4 T 14-10-2018 IPR000644 CBS domain D521_0827 d2f7b5bc63eb1fe85366c61411237a65 151 SMART SM00116 13 60 1.9E-8 T 14-10-2018 IPR000644 CBS domain D521_0827 d2f7b5bc63eb1fe85366c61411237a65 151 SUPERFAMILY SSF54631 1 142 7.45E-27 T 14-10-2018 D521_0827 d2f7b5bc63eb1fe85366c61411237a65 151 Gene3D G3DSA:3.10.580.10 1 147 3.4E-32 T 14-10-2018 D521_0922 3f095c711d9dc7512730af82cfba1636 452 Pfam PF04055 Radical SAM superfamily 145 331 5.6E-29 T 14-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 D521_0922 3f095c711d9dc7512730af82cfba1636 452 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 4 449 1.3E-158 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 D521_0922 3f095c711d9dc7512730af82cfba1636 452 Gene3D G3DSA:3.80.30.20 137 387 2.7E-65 T 14-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe D521_0922 3f095c711d9dc7512730af82cfba1636 452 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 3 452 57.925 T 14-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 D521_0922 3f095c711d9dc7512730af82cfba1636 452 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 4 450 2.3E-94 T 14-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 D521_0922 3f095c711d9dc7512730af82cfba1636 452 Gene3D G3DSA:2.40.50.140 388 452 4.0E-14 T 14-10-2018 D521_0922 3f095c711d9dc7512730af82cfba1636 452 SUPERFAMILY SSF102114 113 380 2.88E-48 T 14-10-2018 D521_0922 3f095c711d9dc7512730af82cfba1636 452 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 143 163 - T 14-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 D521_0922 3f095c711d9dc7512730af82cfba1636 452 Gene3D G3DSA:3.40.50.12160 4 125 3.6E-26 T 14-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily D521_0922 3f095c711d9dc7512730af82cfba1636 452 SMART SM00729 139 373 5.0E-47 T 14-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 D521_0922 3f095c711d9dc7512730af82cfba1636 452 Pfam PF00919 Uncharacterized protein family UPF0004 4 84 2.4E-19 T 14-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 D521_0300 c12c1b59828bb097d65badd61b24ab92 211 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 6 205 1.8E-57 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 D521_0300 c12c1b59828bb097d65badd61b24ab92 211 SMART SM01207 11 196 5.5E-81 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 D521_0300 c12c1b59828bb097d65badd61b24ab92 211 Pfam PF02660 Glycerol-3-phosphate acyltransferase 12 195 1.3E-50 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 D521_0300 c12c1b59828bb097d65badd61b24ab92 211 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 8 204 19.612 T 14-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 D521_0188 3a85ad0e17b32affa871e325bdf9b1c2 429 Pfam PF03471 Transporter associated domain 347 420 1.2E-14 T 14-10-2018 IPR005170 Transporter-associated domain D521_0188 3a85ad0e17b32affa871e325bdf9b1c2 429 SUPERFAMILY SSF54631 200 338 1.77E-26 T 14-10-2018 D521_0188 3a85ad0e17b32affa871e325bdf9b1c2 429 SUPERFAMILY SSF56176 345 424 2.43E-17 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 D521_0188 3a85ad0e17b32affa871e325bdf9b1c2 429 SMART SM01091 345 423 1.7E-19 T 14-10-2018 IPR005170 Transporter-associated domain D521_0188 3a85ad0e17b32affa871e325bdf9b1c2 429 Gene3D G3DSA:3.30.465.10 346 421 4.2E-21 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 D521_0188 3a85ad0e17b32affa871e325bdf9b1c2 429 Pfam PF01595 Domain of unknown function DUF21 16 188 7.5E-42 T 14-10-2018 IPR002550 CNNM, transmembrane domain D521_0188 3a85ad0e17b32affa871e325bdf9b1c2 429 Gene3D G3DSA:3.10.580.10 190 343 2.5E-37 T 14-10-2018 D521_0188 3a85ad0e17b32affa871e325bdf9b1c2 429 Pfam PF00571 CBS domain 209 266 6.8E-5 T 14-10-2018 IPR000644 CBS domain D521_0188 3a85ad0e17b32affa871e325bdf9b1c2 429 Pfam PF00571 CBS domain 282 329 3.3E-5 T 14-10-2018 IPR000644 CBS domain D521_1503 bc6d9097ac6f83f9b190fbc014763403 125 TIGRFAM TIGR00494 crcB: protein CrcB 7 119 6.5E-25 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 D521_1503 bc6d9097ac6f83f9b190fbc014763403 125 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 5 122 17.02 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 D521_1503 bc6d9097ac6f83f9b190fbc014763403 125 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 117 1.1E-19 T 14-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 D521_1999 444bc2b24a59d45d84b9abe39d0468b3 382 Gene3D G3DSA:3.30.460.10 1 127 2.1E-25 T 14-10-2018 D521_1999 444bc2b24a59d45d84b9abe39d0468b3 382 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 154 214 2.0E-9 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 D521_1999 444bc2b24a59d45d84b9abe39d0468b3 382 PIRSF PIRSF000813 247 381 1.3E-5 T 14-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 D521_1999 444bc2b24a59d45d84b9abe39d0468b3 382 PIRSF PIRSF000813 1 237 8.7E-106 T 14-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 D521_1999 444bc2b24a59d45d84b9abe39d0468b3 382 Gene3D G3DSA:1.10.3090.10 128 364 1.4E-27 T 14-10-2018 D521_1999 444bc2b24a59d45d84b9abe39d0468b3 382 SUPERFAMILY SSF81301 1 125 1.05E-28 T 14-10-2018 D521_1999 444bc2b24a59d45d84b9abe39d0468b3 382 Pfam PF01743 Poly A polymerase head domain 3 127 1.2E-15 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 D521_1999 444bc2b24a59d45d84b9abe39d0468b3 382 SUPERFAMILY SSF81891 128 334 1.44E-31 T 14-10-2018 D521_0889 87cffc3672894a9af1e3b2259f418985 65 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 65 4.4E-14 T 14-10-2018 IPR010035 ThiS, thiamine-biosynthesis D521_0889 87cffc3672894a9af1e3b2259f418985 65 Pfam PF02597 ThiS family 7 65 2.1E-13 T 14-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 D521_0889 87cffc3672894a9af1e3b2259f418985 65 SUPERFAMILY SSF54285 1 65 1.15E-13 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp D521_0889 87cffc3672894a9af1e3b2259f418985 65 Gene3D G3DSA:3.10.20.30 1 65 2.7E-15 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_0809 32462e0d893e87bf0f864d3d5cb8494d 301 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 48 272 8.6E-110 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related D521_0809 32462e0d893e87bf0f864d3d5cb8494d 301 SUPERFAMILY SSF52540 78 266 4.91E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0809 32462e0d893e87bf0f864d3d5cb8494d 301 Gene3D G3DSA:3.40.50.300 10 283 3.0E-96 T 14-10-2018 D521_0809 32462e0d893e87bf0f864d3d5cb8494d 301 PIRSF PIRSF028756 14 301 1.6E-131 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 D521_0809 32462e0d893e87bf0f864d3d5cb8494d 301 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 48 272 1.4E-112 T 14-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 D521_0115 1e13df51c7251631f035af7023d62606 80 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 6.4E-22 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 D521_0115 1e13df51c7251631f035af7023d62606 80 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 69 23.06 T 14-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 D521_0115 1e13df51c7251631f035af7023d62606 80 Pfam PF02416 mttA/Hcf106 family 5 55 1.1E-13 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 D521_0432 5da6f57d5aee6692233149a85b5aa291 385 Gene3D G3DSA:2.40.420.20 66 361 1.9E-51 T 14-10-2018 D521_0432 5da6f57d5aee6692233149a85b5aa291 385 Gene3D G3DSA:1.10.287.470 114 191 1.9E-51 T 14-10-2018 D521_0432 5da6f57d5aee6692233149a85b5aa291 385 Gene3D G3DSA:2.40.50.100 80 226 1.9E-51 T 14-10-2018 D521_0432 5da6f57d5aee6692233149a85b5aa291 385 SUPERFAMILY SSF111369 73 266 1.18E-16 T 14-10-2018 D521_0432 5da6f57d5aee6692233149a85b5aa291 385 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 73 266 1.2E-16 T 14-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain D521_0432 5da6f57d5aee6692233149a85b5aa291 385 Gene3D G3DSA:2.40.30.170 69 302 1.9E-51 T 14-10-2018 D521_0432 5da6f57d5aee6692233149a85b5aa291 385 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 56 376 3.1E-53 T 14-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 D521_1448 52e24921f2eabb11018ec645a33ec323 360 PIRSF PIRSF039026 1 356 1.7E-123 T 14-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like D521_1448 52e24921f2eabb11018ec645a33ec323 360 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 25 5.9E-5 T 14-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal D521_1448 52e24921f2eabb11018ec645a33ec323 360 SUPERFAMILY SSF53850 142 277 5.43E-6 T 14-10-2018 D521_1448 52e24921f2eabb11018ec645a33ec323 360 Gene3D G3DSA:3.40.190.170 32 336 8.4E-127 T 14-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily D521_1448 52e24921f2eabb11018ec645a33ec323 360 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 39 319 1.1E-59 T 14-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 D521_1448 52e24921f2eabb11018ec645a33ec323 360 Gene3D G3DSA:3.40.190.10 152 323 8.4E-127 T 14-10-2018 D521_0956 f903b1337fd76ae95c29c26a2aa17cc6 335 SUPERFAMILY SSF103025 11 244 1.88E-42 T 14-10-2018 D521_0956 f903b1337fd76ae95c29c26a2aa17cc6 335 Gene3D G3DSA:2.40.30.160 199 317 1.8E-28 T 14-10-2018 D521_0956 f903b1337fd76ae95c29c26a2aa17cc6 335 Gene3D G3DSA:3.30.70.1400 25 125 1.1E-17 T 14-10-2018 D521_0956 f903b1337fd76ae95c29c26a2aa17cc6 335 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 190 254 5.8E-25 T 14-10-2018 IPR017703 YgfZ/GcvT conserved site D521_2009 8efd34032e4d4db2ee9f9dd6d26d4cdc 222 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 222 32.936 T 14-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_2009 8efd34032e4d4db2ee9f9dd6d26d4cdc 222 SUPERFAMILY SSF53271 10 200 1.24E-43 T 14-10-2018 IPR029057 Phosphoribosyltransferase-like D521_2009 8efd34032e4d4db2ee9f9dd6d26d4cdc 222 Gene3D G3DSA:3.40.50.2020 5 222 8.6E-67 T 14-10-2018 D521_2009 8efd34032e4d4db2ee9f9dd6d26d4cdc 222 Pfam PF00156 Phosphoribosyl transferase domain 46 160 5.1E-14 T 14-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 D521_2009 8efd34032e4d4db2ee9f9dd6d26d4cdc 222 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 14 194 1.4E-52 T 14-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 D521_0041 e353f71f64c9dbb97a98a32d342c2b72 233 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 228 9.8E-105 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 D521_0041 e353f71f64c9dbb97a98a32d342c2b72 233 Gene3D G3DSA:3.40.50.790 68 159 1.2E-78 T 14-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich D521_0041 e353f71f64c9dbb97a98a32d342c2b72 233 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.971 T 14-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 D521_0041 e353f71f64c9dbb97a98a32d342c2b72 233 SUPERFAMILY SSF56808 6 225 9.03E-81 T 14-10-2018 IPR023674 Ribosomal protein L1-like D521_0041 e353f71f64c9dbb97a98a32d342c2b72 233 Gene3D G3DSA:3.30.190.20 25 222 1.2E-78 T 14-10-2018 D521_0041 e353f71f64c9dbb97a98a32d342c2b72 233 PIRSF PIRSF002155 1 227 2.3E-77 T 14-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0041 e353f71f64c9dbb97a98a32d342c2b72 233 Pfam PF00687 Ribosomal protein L1p/L10e family 31 219 4.7E-49 T 14-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein D521_0041 e353f71f64c9dbb97a98a32d342c2b72 233 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 14-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0151 fb629015768b40e6ab6e5213de4f4770 124 SUPERFAMILY SSF110069 4 124 3.66E-47 T 14-10-2018 IPR036767 ApaG domain superfamily D521_0151 fb629015768b40e6ab6e5213de4f4770 124 Gene3D G3DSA:2.60.40.1470 1 124 4.3E-48 T 14-10-2018 IPR036767 ApaG domain superfamily D521_0151 fb629015768b40e6ab6e5213de4f4770 124 Hamap MF_00791 Protein ApaG [apaG]. 1 124 30.629 T 14-10-2018 IPR023065 Uncharacterised protein family ApaG D521_0151 fb629015768b40e6ab6e5213de4f4770 124 Pfam PF04379 ApaG domain 17 101 5.6E-34 T 14-10-2018 IPR007474 ApaG domain D521_1497 84c2bedb1f2a3530cffe83f3fd37c7b2 255 Gene3D G3DSA:3.30.70.100 1 96 1.4E-28 T 14-10-2018 D521_1497 84c2bedb1f2a3530cffe83f3fd37c7b2 255 Hamap MF_00469 UPF0176 protein YceA [yceA]. 2 255 32.548 T 14-10-2018 IPR020936 Uncharacterised protein family UPF0176 D521_1497 84c2bedb1f2a3530cffe83f3fd37c7b2 255 Gene3D G3DSA:3.40.250.10 98 254 9.1E-34 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1497 84c2bedb1f2a3530cffe83f3fd37c7b2 255 SUPERFAMILY SSF52821 97 235 1.51E-23 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1497 84c2bedb1f2a3530cffe83f3fd37c7b2 255 SMART SM00450 116 220 2.4E-10 T 14-10-2018 IPR001763 Rhodanese-like domain D521_0983 e76a65208eab4d1544213aa43bfe9fd5 150 Pfam PF13501 Sulfur oxidation protein SoxY 48 148 7.6E-31 T 14-10-2018 IPR032711 Ig-like SoxY domain D521_0983 e76a65208eab4d1544213aa43bfe9fd5 150 Gene3D G3DSA:2.60.40.2470 29 150 6.1E-37 T 14-10-2018 IPR038162 Ig-like SoxY domain superfamily D521_0983 e76a65208eab4d1544213aa43bfe9fd5 150 TIGRFAM TIGR04488 SoxY_true_GGCGG: thiosulfate oxidation carrier protein SoxY 4 150 3.9E-48 T 14-10-2018 IPR016568 Sulphur oxidation, SoxY D521_0983 e76a65208eab4d1544213aa43bfe9fd5 150 PIRSF PIRSF010312 1 150 5.9E-44 T 14-10-2018 IPR016568 Sulphur oxidation, SoxY D521_0161 88fe46a6f06b6f07196d21244d1fb017 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 3 141 5.9E-34 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 D521_0161 88fe46a6f06b6f07196d21244d1fb017 143 SUPERFAMILY SSF89447 2 130 1.41E-38 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily D521_0161 88fe46a6f06b6f07196d21244d1fb017 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 49.658 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 D521_0161 88fe46a6f06b6f07196d21244d1fb017 143 Gene3D G3DSA:2.40.330.20 1 140 3.3E-37 T 14-10-2018 IPR038619 MraZ superfamily D521_0161 88fe46a6f06b6f07196d21244d1fb017 143 Pfam PF02381 MraZ protein, putative antitoxin-like 3 68 2.0E-13 T 14-10-2018 IPR020603 MraZ domain D521_0161 88fe46a6f06b6f07196d21244d1fb017 143 Pfam PF02381 MraZ protein, putative antitoxin-like 74 129 4.1E-15 T 14-10-2018 IPR020603 MraZ domain D521_0161 88fe46a6f06b6f07196d21244d1fb017 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 2 122 7.0E-56 T 14-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 D521_1092 c137e1c9100e1de24b8c9883a64b2d07 106 Pfam PF02575 YbaB/EbfC DNA-binding family 9 96 3.7E-30 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family D521_1092 c137e1c9100e1de24b8c9883a64b2d07 106 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 102 8.4E-30 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family D521_1092 c137e1c9100e1de24b8c9883a64b2d07 106 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 3 95 21.015 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family D521_1092 c137e1c9100e1de24b8c9883a64b2d07 106 SUPERFAMILY SSF82607 9 100 2.22E-30 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily D521_1092 c137e1c9100e1de24b8c9883a64b2d07 106 Gene3D G3DSA:3.30.1310.10 1 106 2.2E-38 T 14-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily D521_1092 c137e1c9100e1de24b8c9883a64b2d07 106 PIRSF PIRSF004555 1 106 1.2E-31 T 14-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family D521_1677 35c4d34bc2a78de54d15527ada930e05 450 Gene3D G3DSA:1.10.443.10 189 420 4.9E-20 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 D521_1677 35c4d34bc2a78de54d15527ada930e05 450 SUPERFAMILY SSF56349 92 412 5.89E-27 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_1677 35c4d34bc2a78de54d15527ada930e05 450 Gene3D G3DSA:1.10.150.130 76 183 3.9E-6 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 Pfam PF10410 DnaB-helicase binding domain of primase 375 425 5.5E-8 T 14-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 SMART SM00400 35 89 6.1E-35 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 Gene3D G3DSA:3.90.980.10 108 245 7.1E-40 T 14-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 SUPERFAMILY SSF57783 1 100 2.55E-36 T 14-10-2018 D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 Pfam PF13662 Toprim domain 266 330 7.2E-17 T 14-10-2018 IPR006171 TOPRIM domain D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 Pfam PF08275 DNA primase catalytic core, N-terminal domain 125 256 3.0E-36 T 14-10-2018 IPR013264 DNA primase, catalytic core, N-terminal D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 Pfam PF01807 CHC2 zinc finger 5 100 1.0E-39 T 14-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 Hamap MF_00974 DNA primase [dnaG]. 3 647 28.182 T 14-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 Gene3D G3DSA:3.90.580.10 2 101 3.3E-38 T 14-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 SMART SM00493 264 335 6.8E-15 T 14-10-2018 IPR006171 TOPRIM domain D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 Gene3D G3DSA:3.40.1360.10 246 372 2.0E-43 T 14-10-2018 D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 TIGRFAM TIGR01391 dnaG: DNA primase 4 421 9.9E-142 T 14-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 D521_1688 0cbcaee300776bd815e4e26c8c7cce62 649 SUPERFAMILY SSF56731 115 423 1.22E-100 T 14-10-2018 D521_0001 5fe9374b8876580c947155f06a5f843e 474 SMART SM00760 382 451 2.3E-41 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 D521_0001 5fe9374b8876580c947155f06a5f843e 474 SUPERFAMILY SSF52540 138 350 5.3E-42 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0001 5fe9374b8876580c947155f06a5f843e 474 Gene3D G3DSA:1.10.8.60 305 375 3.7E-21 T 14-10-2018 D521_0001 5fe9374b8876580c947155f06a5f843e 474 Pfam PF11638 DnaA N-terminal domain 18 79 1.3E-15 T 14-10-2018 IPR024633 DnaA N-terminal domain D521_0001 5fe9374b8876580c947155f06a5f843e 474 Gene3D G3DSA:3.30.300.180 16 120 1.7E-19 T 14-10-2018 IPR038454 DnaA, N-terminal domain superfamily D521_0001 5fe9374b8876580c947155f06a5f843e 474 Gene3D G3DSA:1.10.1750.10 376 474 3.5E-35 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 D521_0001 5fe9374b8876580c947155f06a5f843e 474 Gene3D G3DSA:3.40.50.300 137 304 2.5E-47 T 14-10-2018 D521_0001 5fe9374b8876580c947155f06a5f843e 474 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 16 473 31.64 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 D521_0001 5fe9374b8876580c947155f06a5f843e 474 ProSitePatterns PS01008 DnaA protein signature. 432 451 - T 14-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 D521_0001 5fe9374b8876580c947155f06a5f843e 474 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 19 472 2.0E-168 T 14-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 D521_0001 5fe9374b8876580c947155f06a5f843e 474 SUPERFAMILY SSF48295 370 474 1.46E-35 T 14-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 D521_0001 5fe9374b8876580c947155f06a5f843e 474 Pfam PF00308 Bacterial dnaA protein 139 355 2.5E-85 T 14-10-2018 IPR013317 Chromosomal replication initiator protein DnaA D521_0001 5fe9374b8876580c947155f06a5f843e 474 SMART SM00382 171 305 4.3E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0001 5fe9374b8876580c947155f06a5f843e 474 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 383 451 1.4E-30 T 14-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 D521_0001 5fe9374b8876580c947155f06a5f843e 474 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 270 297 3.3E-49 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like D521_0001 5fe9374b8876580c947155f06a5f843e 474 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 204 218 3.3E-49 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like D521_0001 5fe9374b8876580c947155f06a5f843e 474 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 172 192 3.3E-49 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like D521_0001 5fe9374b8876580c947155f06a5f843e 474 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 236 250 3.3E-49 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like D521_0001 5fe9374b8876580c947155f06a5f843e 474 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 432 451 3.3E-49 T 14-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like D521_1080 2ab069cc70549e53cf22879886e7b63c 464 SUPERFAMILY SSF50249 4 69 1.09E-5 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1080 2ab069cc70549e53cf22879886e7b63c 464 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 285 462 4.7E-17 T 14-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 D521_1080 2ab069cc70549e53cf22879886e7b63c 464 Gene3D G3DSA:3.40.50.150 85 458 9.5E-97 T 14-10-2018 D521_1080 2ab069cc70549e53cf22879886e7b63c 464 SUPERFAMILY SSF53335 73 463 6.45E-65 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1080 2ab069cc70549e53cf22879886e7b63c 464 Gene3D G3DSA:3.40.1350.30 132 287 9.5E-97 T 14-10-2018 D521_1080 2ab069cc70549e53cf22879886e7b63c 464 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 32 456 1.5E-82 T 14-10-2018 D521_1080 2ab069cc70549e53cf22879886e7b63c 464 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 4 464 65.604 T 14-10-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 D521_1080 2ab069cc70549e53cf22879886e7b63c 464 Gene3D G3DSA:2.40.50.140 2 84 5.3E-16 T 14-10-2018 D521_1080 2ab069cc70549e53cf22879886e7b63c 464 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 446 456 - T 14-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site D521_1487 9da8aed3c30b0f5ed6581e9f885feb0b 225 Pfam PF13419 Haloacid dehalogenase-like hydrolase 12 191 9.8E-33 T 14-10-2018 D521_1487 9da8aed3c30b0f5ed6581e9f885feb0b 225 Gene3D G3DSA:3.40.50.1000 12 212 6.4E-51 T 14-10-2018 IPR023214 HAD superfamily D521_1487 9da8aed3c30b0f5ed6581e9f885feb0b 225 Gene3D G3DSA:1.10.150.240 24 90 6.4E-51 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 D521_1487 9da8aed3c30b0f5ed6581e9f885feb0b 225 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 98 190 1.5E-7 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1487 9da8aed3c30b0f5ed6581e9f885feb0b 225 SUPERFAMILY SSF56784 9 222 5.02E-55 T 14-10-2018 IPR036412 HAD-like superfamily D521_1487 9da8aed3c30b0f5ed6581e9f885feb0b 225 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 107 186 1.9E-8 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1487 9da8aed3c30b0f5ed6581e9f885feb0b 225 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 12 220 4.4E-50 T 14-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 D521_1433 0a32f1d3ce71871dfaf932afa70d328e 207 SUPERFAMILY SSF52972 16 198 1.24E-53 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like D521_1433 0a32f1d3ce71871dfaf932afa70d328e 207 Hamap MF_00528 Septum formation protein Maf [maf]. 17 203 27.33 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 D521_1433 0a32f1d3ce71871dfaf932afa70d328e 207 Pfam PF02545 Maf-like protein 17 198 4.8E-43 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 D521_1433 0a32f1d3ce71871dfaf932afa70d328e 207 PIRSF PIRSF006305 9 203 1.8E-43 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 D521_1433 0a32f1d3ce71871dfaf932afa70d328e 207 Gene3D G3DSA:3.90.950.10 16 203 6.9E-53 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like D521_1433 0a32f1d3ce71871dfaf932afa70d328e 207 TIGRFAM TIGR00172 maf: septum formation protein Maf 16 197 3.1E-43 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 D521_1911 ab356b0283a97607da84464083a73e75 296 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 290 39.023 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 D521_1911 ab356b0283a97607da84464083a73e75 296 Pfam PF03668 P-loop ATPase protein family 1 276 2.1E-93 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 D521_1911 ab356b0283a97607da84464083a73e75 296 PIRSF PIRSF005052 1 291 2.8E-105 T 14-10-2018 IPR005337 RapZ-like family GO:0005524 D521_1911 ab356b0283a97607da84464083a73e75 296 Gene3D G3DSA:3.40.50.300 2 161 2.0E-6 T 14-10-2018 D521_1911 ab356b0283a97607da84464083a73e75 296 SUPERFAMILY SSF52540 5 159 7.56E-10 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0712 f157cd1c456e94f38259c41f76e8642a 404 Gene3D G3DSA:3.40.50.10540 10 396 1.4E-140 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_0712 f157cd1c456e94f38259c41f76e8642a 404 Pfam PF02515 CoA-transferase family III 11 379 4.3E-132 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 D521_0712 f157cd1c456e94f38259c41f76e8642a 404 Gene3D G3DSA:3.30.1540.10 239 330 1.4E-140 T 14-10-2018 D521_0712 f157cd1c456e94f38259c41f76e8642a 404 SUPERFAMILY SSF89796 9 401 6.54E-142 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_1792 e3e38d198a4076aeaa6bd4442c5f2fc1 246 SUPERFAMILY SSF52540 3 244 5.11E-62 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1792 e3e38d198a4076aeaa6bd4442c5f2fc1 246 SMART SM00382 29 223 5.0E-10 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1792 e3e38d198a4076aeaa6bd4442c5f2fc1 246 Pfam PF00005 ABC transporter 21 175 4.3E-27 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_1792 e3e38d198a4076aeaa6bd4442c5f2fc1 246 Gene3D G3DSA:3.40.50.300 3 246 3.2E-61 T 14-10-2018 D521_1970 2df0a05b816bb50f29854724bcfedfbd 261 Pfam PF07103 Protein of unknown function (DUF1365) 8 254 1.8E-66 T 14-10-2018 IPR010775 Protein of unknown function DUF1365 D521_0519 56d88ed50efd602fc0feadec56ff7930 183 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 162 5.4E-28 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ D521_1104 a46dacacbefd4ad8175565596b693ed2 158 SUPERFAMILY SSF51306 26 145 2.22E-37 T 14-10-2018 IPR036286 LexA/Signal peptidase-like superfamily D521_1104 a46dacacbefd4ad8175565596b693ed2 158 Gene3D G3DSA:2.10.109.10 33 148 1.7E-46 T 14-10-2018 D521_1104 a46dacacbefd4ad8175565596b693ed2 158 Pfam PF00717 Peptidase S24-like 63 130 4.4E-19 T 14-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C D521_1104 a46dacacbefd4ad8175565596b693ed2 158 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 60 70 5.4E-8 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 D521_1104 a46dacacbefd4ad8175565596b693ed2 158 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 99 111 5.4E-8 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 D521_1104 a46dacacbefd4ad8175565596b693ed2 158 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 71 82 5.4E-8 T 14-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 D521_0150 df3d6c7e1e3140924d56591a3ef90303 241 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 41 55 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 D521_0150 df3d6c7e1e3140924d56591a3ef90303 241 SUPERFAMILY SSF51366 11 234 2.18E-70 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 D521_0150 df3d6c7e1e3140924d56591a3ef90303 241 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 14 232 6.1E-92 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 D521_0150 df3d6c7e1e3140924d56591a3ef90303 241 Pfam PF00834 Ribulose-phosphate 3 epimerase family 14 219 4.8E-86 T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 D521_0150 df3d6c7e1e3140924d56591a3ef90303 241 Gene3D G3DSA:3.20.20.70 12 237 1.3E-80 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0150 df3d6c7e1e3140924d56591a3ef90303 241 PIRSF PIRSF001461 8 241 3.3E-100 T 14-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 D521_0150 df3d6c7e1e3140924d56591a3ef90303 241 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 148 170 - T 14-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 D521_1154 7a5f16861096bf3119e28c9f44202768 381 SUPERFAMILY SSF51395 5 376 3.97E-106 T 14-10-2018 D521_1154 7a5f16861096bf3119e28c9f44202768 381 Pfam PF01070 FMN-dependent dehydrogenase 15 376 1.0E-133 T 14-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 D521_1154 7a5f16861096bf3119e28c9f44202768 381 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 274 280 - T 14-10-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 Reactome: R-HSA-9033241 D521_1154 7a5f16861096bf3119e28c9f44202768 381 Gene3D G3DSA:3.20.20.70 2 379 7.2E-133 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1154 7a5f16861096bf3119e28c9f44202768 381 PIRSF PIRSF000138 2 380 9.6E-127 T 14-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 D521_0332 4a2c71f0792d907e9bdc5a32e6e1eba2 290 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 224 3.4E-42 T 14-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 D521_0332 4a2c71f0792d907e9bdc5a32e6e1eba2 290 Gene3D G3DSA:3.40.1010.10 7 122 5.3E-38 T 14-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 D521_0332 4a2c71f0792d907e9bdc5a32e6e1eba2 290 SUPERFAMILY SSF53790 5 248 1.28E-56 T 14-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 D521_0332 4a2c71f0792d907e9bdc5a32e6e1eba2 290 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 8 247 1.2E-74 T 14-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 D521_0332 4a2c71f0792d907e9bdc5a32e6e1eba2 290 Gene3D G3DSA:3.30.950.10 123 272 1.3E-23 T 14-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 D521_0332 4a2c71f0792d907e9bdc5a32e6e1eba2 290 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 13 27 - T 14-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 D521_1367 b320fbc739c279e09d2573be03c39c59 80 Gene3D G3DSA:3.40.1440.10 1 80 9.2E-30 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 D521_1367 b320fbc739c279e09d2573be03c39c59 80 SUPERFAMILY SSF82771 3 73 1.26E-11 T 14-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 D521_1367 b320fbc739c279e09d2573be03c39c59 80 Pfam PF01541 GIY-YIG catalytic domain 3 72 3.4E-15 T 14-10-2018 IPR000305 GIY-YIG endonuclease D521_1586 48514641d2e37f05e5d109ab2fb0d391 88 Pfam PF01527 Transposase 2 69 5.2E-19 T 14-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 D521_1586 48514641d2e37f05e5d109ab2fb0d391 88 Gene3D G3DSA:1.10.10.60 12 85 1.6E-6 T 14-10-2018 D521_1586 48514641d2e37f05e5d109ab2fb0d391 88 SUPERFAMILY SSF46689 1 70 7.53E-16 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 D521_1463 4f428d04a9e395beabc8331d8ee6020d 190 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 14-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 D521_1463 4f428d04a9e395beabc8331d8ee6020d 190 SUPERFAMILY SSF52402 1 188 3.98E-66 T 14-10-2018 D521_1463 4f428d04a9e395beabc8331d8ee6020d 190 Gene3D G3DSA:3.40.50.620 1 190 1.2E-65 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1463 4f428d04a9e395beabc8331d8ee6020d 190 SMART SM00893 23 189 4.5E-47 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 D521_1463 4f428d04a9e395beabc8331d8ee6020d 190 Pfam PF01012 Electron transfer flavoprotein domain 29 183 5.3E-40 T 14-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 D521_1491 e8d573885598b0e8896fa93fb566e20d 685 Pfam PF00593 TonB dependent receptor 235 683 1.3E-43 T 14-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel D521_1491 e8d573885598b0e8896fa93fb566e20d 685 SUPERFAMILY SSF56935 31 684 7.69E-110 T 14-10-2018 D521_1491 e8d573885598b0e8896fa93fb566e20d 685 Gene3D G3DSA:2.170.130.10 45 163 1.1E-23 T 14-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily D521_1491 e8d573885598b0e8896fa93fb566e20d 685 Gene3D G3DSA:2.40.170.20 172 684 5.3E-95 T 14-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily D521_1491 e8d573885598b0e8896fa93fb566e20d 685 Pfam PF07715 TonB-dependent Receptor Plug Domain 45 155 1.1E-19 T 14-10-2018 IPR012910 TonB-dependent receptor, plug domain D521_0852 7e19fcb372b57c58658bc07d51a8e389 184 Pfam PF13649 Methyltransferase domain 25 108 1.1E-7 T 14-10-2018 D521_0852 7e19fcb372b57c58658bc07d51a8e389 184 SUPERFAMILY SSF53335 11 163 1.96E-21 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0852 7e19fcb372b57c58658bc07d51a8e389 184 Gene3D G3DSA:3.40.50.150 2 168 3.3E-20 T 14-10-2018 D521_2102 ce6cc15367d99ea836bb38235a2d7a4c 415 SUPERFAMILY SSF52540 6 220 7.23E-11 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_2102 ce6cc15367d99ea836bb38235a2d7a4c 415 Pfam PF07693 KAP family P-loop domain 31 252 7.0E-33 T 14-10-2018 IPR011646 KAP family P-loop domain D521_0496 b1571d55a505b7cf6c5159869ea997f8 332 PIRSF PIRSF017082 1 332 9.1E-77 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0496 b1571d55a505b7cf6c5159869ea997f8 332 SUPERFAMILY SSF53850 118 298 7.45E-11 T 14-10-2018 D521_0496 b1571d55a505b7cf6c5159869ea997f8 332 Gene3D G3DSA:3.40.190.150 36 322 5.8E-106 T 14-10-2018 D521_0496 b1571d55a505b7cf6c5159869ea997f8 332 Gene3D G3DSA:3.40.190.10 133 257 5.8E-106 T 14-10-2018 D521_0496 b1571d55a505b7cf6c5159869ea997f8 332 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 56 328 7.2E-83 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1069 e2a329571aae13a3afbc09a83304d13e 497 SUPERFAMILY SSF117892 224 339 3.92E-21 T 14-10-2018 IPR036013 Band 7/SPFH domain superfamily D521_1069 e2a329571aae13a3afbc09a83304d13e 497 Pfam PF12221 Bacterial membrane protein N terminal 8 90 4.5E-8 T 14-10-2018 IPR020980 Menbrane protein HflK, N-terminal D521_1069 e2a329571aae13a3afbc09a83304d13e 497 TIGRFAM TIGR01933 hflK: HflK protein 163 436 2.7E-90 T 14-10-2018 IPR010201 HflK GO:0016021 D521_1069 e2a329571aae13a3afbc09a83304d13e 497 Gene3D G3DSA:3.30.479.30 216 325 4.9E-20 T 14-10-2018 D521_1069 e2a329571aae13a3afbc09a83304d13e 497 SMART SM00244 161 334 3.5E-27 T 14-10-2018 IPR001107 Band 7 domain D521_1069 e2a329571aae13a3afbc09a83304d13e 497 Pfam PF01145 SPFH domain / Band 7 family 165 348 3.1E-26 T 14-10-2018 IPR001107 Band 7 domain D521_0584 6cf439f7eb26c44f493a58f015df4460 349 Pfam PF02615 Malate/L-lactate dehydrogenase 5 335 3.4E-109 T 14-10-2018 IPR003767 Malate/L-lactate dehydrogenase-like GO:0016491|GO:0055114 D521_0584 6cf439f7eb26c44f493a58f015df4460 349 Gene3D G3DSA:1.10.1530.10 10 339 8.1E-110 T 14-10-2018 D521_0584 6cf439f7eb26c44f493a58f015df4460 349 SUPERFAMILY SSF89733 3 344 1.83E-103 T 14-10-2018 IPR036111 Malate/L-sulfolactate/L-lactate dehydrogenase-like superfamily GO:0016491|GO:0055114 D521_0584 6cf439f7eb26c44f493a58f015df4460 349 Gene3D G3DSA:3.30.1370.60 68 318 8.1E-110 T 14-10-2018 D521_0993 0ff9a34a04f0b7647b40e3930bb0ba8b 188 Pfam PF02674 Colicin V production protein 12 153 1.5E-33 T 14-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 Gene3D G3DSA:1.25.40.10 13 90 7.4E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 SUPERFAMILY SSF48452 11 263 1.26E-42 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 Gene3D G3DSA:1.25.40.10 182 265 1.6E-19 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 Pfam PF14559 Tetratricopeptide repeat 129 184 5.7E-6 T 14-10-2018 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 Pfam PF14559 Tetratricopeptide repeat 197 260 8.0E-8 T 14-10-2018 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 Gene3D G3DSA:1.25.40.10 91 181 3.0E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 SMART SM00028 48 81 0.18 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 SMART SM00028 14 47 170.0 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 SMART SM00028 82 115 2.3E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 SMART SM00028 184 217 1.5E-4 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 SMART SM00028 150 183 0.078 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 SMART SM00028 116 149 0.0035 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 SMART SM00028 218 251 9.5E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0662 1406276f0dd2230b6e0507d7169f465f 267 Pfam PF13414 TPR repeat 59 94 3.4E-7 T 14-10-2018 D521_0890 a09a4f0c9d021694090a44b83b690baf 384 Pfam PF01266 FAD dependent oxidoreductase 10 348 4.0E-33 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 D521_0890 a09a4f0c9d021694090a44b83b690baf 384 Gene3D G3DSA:3.30.9.10 94 313 3.2E-52 T 14-10-2018 D521_0890 a09a4f0c9d021694090a44b83b690baf 384 Gene3D G3DSA:3.50.50.60 11 349 3.2E-52 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0890 a09a4f0c9d021694090a44b83b690baf 384 SUPERFAMILY SSF51905 9 274 9.06E-25 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0806 fafb7616598ed2a81542df27f50eb884 342 SUPERFAMILY SSF53756 2 329 1.44E-61 T 14-10-2018 D521_0806 fafb7616598ed2a81542df27f50eb884 342 Gene3D G3DSA:3.40.50.2000 1 181 5.9E-22 T 14-10-2018 D521_0806 fafb7616598ed2a81542df27f50eb884 342 Pfam PF13692 Glycosyl transferases group 1 180 295 2.1E-17 T 14-10-2018 D521_0806 fafb7616598ed2a81542df27f50eb884 342 Pfam PF13439 Glycosyltransferase Family 4 14 165 1.3E-17 T 14-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 D521_0806 fafb7616598ed2a81542df27f50eb884 342 Gene3D G3DSA:3.40.50.2000 182 320 9.1E-23 T 14-10-2018 D521_2034 6acd0c5e49c0187bc0de5367c57f3456 250 SUPERFAMILY SSF56300 1 250 2.81E-43 T 14-10-2018 D521_2034 6acd0c5e49c0187bc0de5367c57f3456 250 Gene3D G3DSA:3.60.21.10 1 250 4.7E-57 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like D521_2034 6acd0c5e49c0187bc0de5367c57f3456 250 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 211 4.7E-19 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 D521_2034 6acd0c5e49c0187bc0de5367c57f3456 250 PIRSF PIRSF000883 3 250 3.1E-41 T 14-10-2018 IPR011152 Phosphoesterase MJ0912 D521_0487 d8595da2e9842756e85963c5432337b6 425 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 424 42.843 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_0487 d8595da2e9842756e85963c5432337b6 425 Gene3D G3DSA:3.30.470.20 193 331 1.0E-55 T 14-10-2018 D521_0487 d8595da2e9842756e85963c5432337b6 425 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 104 2.9E-37 T 14-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_0487 d8595da2e9842756e85963c5432337b6 425 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 333 422 1.3E-28 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_0487 d8595da2e9842756e85963c5432337b6 425 SUPERFAMILY SSF52440 1 105 4.17E-35 T 14-10-2018 IPR016185 Pre-ATP-grasp domain superfamily D521_0487 d8595da2e9842756e85963c5432337b6 425 SMART SM01210 332 424 5.3E-52 T 14-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_0487 d8595da2e9842756e85963c5432337b6 425 SUPERFAMILY SSF56059 106 328 3.18E-63 T 14-10-2018 D521_0487 d8595da2e9842756e85963c5432337b6 425 SUPERFAMILY SSF51246 331 424 7.85E-31 T 14-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 D521_0487 d8595da2e9842756e85963c5432337b6 425 Gene3D G3DSA:3.40.50.20 2 97 8.7E-37 T 14-10-2018 D521_0487 d8595da2e9842756e85963c5432337b6 425 Gene3D G3DSA:3.90.600.10 332 425 8.8E-34 T 14-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_0487 d8595da2e9842756e85963c5432337b6 425 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 105 298 6.2E-78 T 14-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_0487 d8595da2e9842756e85963c5432337b6 425 SMART SM01209 105 298 1.0E-135 T 14-10-2018 D521_0487 d8595da2e9842756e85963c5432337b6 425 Gene3D G3DSA:3.30.1490.20 123 192 3.5E-27 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 D521_0487 d8595da2e9842756e85963c5432337b6 425 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 424 3.0E-172 T 14-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 D521_0096 8b64a373fae741f60893913283b86641 265 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 13 264 3.9E-83 T 14-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria D521_0096 8b64a373fae741f60893913283b86641 265 Pfam PF02405 Permease MlaE 51 260 5.6E-74 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 D521_0019 8b780b461b7bab720b9b197cf3521547 178 Gene3D G3DSA:1.10.520.20 2 106 4.1E-22 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0019 8b780b461b7bab720b9b197cf3521547 178 SUPERFAMILY SSF47928 3 105 8.63E-19 T 14-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0019 8b780b461b7bab720b9b197cf3521547 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 176 1.0E-47 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0019 8b780b461b7bab720b9b197cf3521547 178 PRINTS PR00125 ATP synthase delta subunit signature 74 85 1.5E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0019 8b780b461b7bab720b9b197cf3521547 178 PRINTS PR00125 ATP synthase delta subunit signature 151 169 1.5E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0019 8b780b461b7bab720b9b197cf3521547 178 PRINTS PR00125 ATP synthase delta subunit signature 85 99 1.5E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0019 8b780b461b7bab720b9b197cf3521547 178 PRINTS PR00125 ATP synthase delta subunit signature 136 151 1.5E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0019 8b780b461b7bab720b9b197cf3521547 178 PRINTS PR00125 ATP synthase delta subunit signature 7 26 1.5E-23 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0019 8b780b461b7bab720b9b197cf3521547 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 178 19.032 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0019 8b780b461b7bab720b9b197cf3521547 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 176 2.3E-35 T 14-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_1923 f1edeb5500dd3f87a84c2530ba6d013e 448 SUPERFAMILY SSF63411 37 237 9.33E-33 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 D521_1923 f1edeb5500dd3f87a84c2530ba6d013e 448 Gene3D G3DSA:3.30.830.10 257 448 2.3E-50 T 14-10-2018 D521_1923 f1edeb5500dd3f87a84c2530ba6d013e 448 Gene3D G3DSA:3.30.830.10 36 243 1.2E-37 T 14-10-2018 D521_1923 f1edeb5500dd3f87a84c2530ba6d013e 448 Pfam PF00675 Insulinase (Peptidase family M16) 49 189 1.9E-6 T 14-10-2018 IPR011765 Peptidase M16, N-terminal D521_1923 f1edeb5500dd3f87a84c2530ba6d013e 448 Pfam PF05193 Peptidase M16 inactive domain 197 379 1.3E-37 T 14-10-2018 IPR007863 Peptidase M16, C-terminal D521_1923 f1edeb5500dd3f87a84c2530ba6d013e 448 SUPERFAMILY SSF63411 265 447 3.17E-44 T 14-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 D521_1965 c36fe17dc8936e0d2c0ce5e557c73392 266 SUPERFAMILY SSF55681 5 214 2.49E-40 T 14-10-2018 D521_1965 c36fe17dc8936e0d2c0ce5e557c73392 266 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 11 263 1.7E-38 T 14-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 D521_1965 c36fe17dc8936e0d2c0ce5e557c73392 266 SUPERFAMILY SSF50037 227 263 3.34E-6 T 14-10-2018 IPR008988 Transcriptional repressor, C-terminal D521_1965 c36fe17dc8936e0d2c0ce5e557c73392 266 Gene3D G3DSA:3.30.930.10 2 215 3.3E-45 T 14-10-2018 D521_1965 c36fe17dc8936e0d2c0ce5e557c73392 266 Pfam PF03099 Biotin/lipoate A/B protein ligase family 12 145 2.0E-13 T 14-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 D521_1965 c36fe17dc8936e0d2c0ce5e557c73392 266 Gene3D G3DSA:2.30.30.100 216 265 3.9E-12 T 14-10-2018 D521_1965 c36fe17dc8936e0d2c0ce5e557c73392 266 Pfam PF02237 Biotin protein ligase C terminal domain 224 263 1.7E-6 T 14-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 D521_0652 dff1e53aa427a5e9e474dc31d416bc48 534 SUPERFAMILY SSF56954 24 447 4.19E-83 T 14-10-2018 D521_0652 dff1e53aa427a5e9e474dc31d416bc48 534 Gene3D G3DSA:2.20.200.10 82 336 4.7E-105 T 14-10-2018 D521_0652 dff1e53aa427a5e9e474dc31d416bc48 534 Gene3D G3DSA:1.20.1600.10 35 447 4.7E-105 T 14-10-2018 D521_0652 dff1e53aa427a5e9e474dc31d416bc48 534 TIGRFAM TIGR01845 outer_NodT: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family 11 447 3.0E-78 T 14-10-2018 IPR010131 RND efflux system, outer membrane lipoprotein, NodT GO:0016020|GO:0022857|GO:0055085 D521_0652 dff1e53aa427a5e9e474dc31d416bc48 534 Pfam PF02321 Outer membrane efflux protein 45 237 1.2E-20 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_0652 dff1e53aa427a5e9e474dc31d416bc48 534 Pfam PF02321 Outer membrane efflux protein 269 445 4.9E-13 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_1140 3c9110469d6c30e4cd5e124a57bcf06e 78 TIGRFAM TIGR02450 TIGR02450: tryptophan-rich conserved hypothetical protein 15 78 9.2E-11 T 14-10-2018 IPR012663 Conserved hypothetical protein CHP02450, tryptophan-rich D521_1140 3c9110469d6c30e4cd5e124a57bcf06e 78 Pfam PF09493 Tryptophan-rich protein (DUF2389) 17 77 9.9E-18 T 14-10-2018 IPR012663 Conserved hypothetical protein CHP02450, tryptophan-rich D521_1780 856f78bcdbf048b311e00b32add3d1b7 112 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 15 101 2.2E-38 T 14-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 D521_0223 176450239512a0e9b14d53f4de8fde43 323 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 2 320 5.7E-73 T 14-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 D521_0223 176450239512a0e9b14d53f4de8fde43 323 SUPERFAMILY SSF144083 255 317 2.48E-17 T 14-10-2018 D521_0223 176450239512a0e9b14d53f4de8fde43 323 Pfam PF01544 CorA-like Mg2+ transporter protein 30 315 2.2E-56 T 14-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 D521_0223 176450239512a0e9b14d53f4de8fde43 323 Gene3D G3DSA:1.20.58.340 244 320 2.0E-23 T 14-10-2018 D521_0223 176450239512a0e9b14d53f4de8fde43 323 SUPERFAMILY SSF143865 1 259 6.54E-39 T 14-10-2018 D521_0223 176450239512a0e9b14d53f4de8fde43 323 Gene3D G3DSA:3.30.460.20 2 126 1.9E-10 T 14-10-2018 D521_0748 7ae7d2b3f305631f28133c4eb1370e46 199 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 32 159 8.8E-40 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0748 7ae7d2b3f305631f28133c4eb1370e46 199 SUPERFAMILY SSF143243 7 180 5.23E-53 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0748 7ae7d2b3f305631f28133c4eb1370e46 199 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 121 142 - T 14-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0748 7ae7d2b3f305631f28133c4eb1370e46 199 Gene3D G3DSA:3.30.460.80 1 140 1.7E-42 T 14-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0748 7ae7d2b3f305631f28133c4eb1370e46 199 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 33 161 6.4E-42 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0748 7ae7d2b3f305631f28133c4eb1370e46 199 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 87 148 5.0E-23 T 14-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0748 7ae7d2b3f305631f28133c4eb1370e46 199 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 8 168 34.001 T 14-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0395 c0aa10b1f5c6e82dafb54eb8ebbe8803 132 Gene3D G3DSA:3.10.180.10 9 132 7.3E-31 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase D521_0395 c0aa10b1f5c6e82dafb54eb8ebbe8803 132 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 128 1.9E-9 T 14-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain D521_0395 c0aa10b1f5c6e82dafb54eb8ebbe8803 132 SUPERFAMILY SSF54593 6 131 3.03E-22 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase D521_1479 17594347b6123ce88cbb06160ab6c9f2 442 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 13 442 32.156 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 D521_1479 17594347b6123ce88cbb06160ab6c9f2 442 SUPERFAMILY SSF55205 8 439 6.41E-119 T 14-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 D521_1479 17594347b6123ce88cbb06160ab6c9f2 442 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 17 440 7.2E-135 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 D521_1479 17594347b6123ce88cbb06160ab6c9f2 442 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 435 8.4E-128 T 14-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 D521_1479 17594347b6123ce88cbb06160ab6c9f2 442 PIRSF PIRSF000505 5 442 9.5E-140 T 14-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 D521_1479 17594347b6123ce88cbb06160ab6c9f2 442 ProSitePatterns PS00885 EPSP synthase signature 2. 350 368 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 D521_1479 17594347b6123ce88cbb06160ab6c9f2 442 Gene3D G3DSA:3.65.10.10 23 241 3.8E-136 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 D521_1479 17594347b6123ce88cbb06160ab6c9f2 442 ProSitePatterns PS00104 EPSP synthase signature 1. 91 105 - T 14-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 D521_1479 17594347b6123ce88cbb06160ab6c9f2 442 Gene3D G3DSA:3.65.10.10 248 436 3.8E-136 T 14-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 D521_1971 63add0d0c240c0e54d14c6e38dc0e814 431 Pfam PF02353 Mycolic acid cyclopropane synthetase 142 414 5.2E-82 T 14-10-2018 D521_1971 63add0d0c240c0e54d14c6e38dc0e814 431 SUPERFAMILY SSF53335 150 418 3.03E-67 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1971 63add0d0c240c0e54d14c6e38dc0e814 431 Gene3D G3DSA:3.40.50.150 148 423 5.8E-92 T 14-10-2018 D521_1971 63add0d0c240c0e54d14c6e38dc0e814 431 PIRSF PIRSF003085 18 430 1.2E-119 T 14-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 D521_0260 4563452a237836faf0657da6b20ff304 279 SUPERFAMILY SSF53335 25 278 2.23E-36 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0260 4563452a237836faf0657da6b20ff304 279 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 63 278 4.1E-46 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 D521_0260 4563452a237836faf0657da6b20ff304 279 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 32 279 28.026 T 14-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 D521_0260 4563452a237836faf0657da6b20ff304 279 Pfam PF02390 Putative methyltransferase 73 221 4.2E-48 T 14-10-2018 D521_0703 b2d785c5b778867a2c12f48c38a29d62 378 Gene3D G3DSA:3.30.9.10 86 329 2.1E-136 T 14-10-2018 D521_0703 b2d785c5b778867a2c12f48c38a29d62 378 Pfam PF01266 FAD dependent oxidoreductase 5 370 8.5E-56 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 D521_0703 b2d785c5b778867a2c12f48c38a29d62 378 SUPERFAMILY SSF51905 4 374 4.86E-37 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0703 b2d785c5b778867a2c12f48c38a29d62 378 Gene3D G3DSA:3.50.50.60 5 368 2.1E-136 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0238 ee4038307eb816d12f8038cfde10bb47 428 Gene3D G3DSA:3.40.309.10 232 385 4.5E-167 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 D521_0238 ee4038307eb816d12f8038cfde10bb47 428 PIRSF PIRSF000151 4 428 4.4E-172 T 14-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 D521_0238 ee4038307eb816d12f8038cfde10bb47 428 Pfam PF00171 Aldehyde dehydrogenase family 14 287 1.2E-17 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 D521_0238 ee4038307eb816d12f8038cfde10bb47 428 Pfam PF00171 Aldehyde dehydrogenase family 318 384 5.0E-7 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 D521_0238 ee4038307eb816d12f8038cfde10bb47 428 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 11 427 40.586 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 D521_0238 ee4038307eb816d12f8038cfde10bb47 428 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 334 356 - T 14-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 D521_0238 ee4038307eb816d12f8038cfde10bb47 428 SUPERFAMILY SSF53720 10 427 3.14E-116 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 D521_0238 ee4038307eb816d12f8038cfde10bb47 428 Gene3D G3DSA:3.40.605.10 18 424 4.5E-167 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 D521_0238 ee4038307eb816d12f8038cfde10bb47 428 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 19 417 9.3E-153 T 14-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 D521_0621 6e6265f6848a884ecafb37aafa6274f6 350 Gene3D G3DSA:1.20.1530.20 1 342 4.5E-31 T 14-10-2018 IPR038770 Sodium/solute symporter superfamily D521_0621 6e6265f6848a884ecafb37aafa6274f6 350 PIRSF PIRSF005508 1 350 3.4E-132 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 D521_0621 6e6265f6848a884ecafb37aafa6274f6 350 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 8 337 1.7E-129 T 14-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 D521_0621 6e6265f6848a884ecafb37aafa6274f6 350 Pfam PF01758 Sodium Bile acid symporter family 53 249 3.0E-58 T 14-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 D521_1918 a172efa5c0a2b1974df2433ff137a43a 212 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 1 93 21.597 T 14-10-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 D521_1918 a172efa5c0a2b1974df2433ff137a43a 212 SUPERFAMILY SSF50715 2 187 1.5E-52 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_1918 a172efa5c0a2b1974df2433ff137a43a 212 Pfam PF01386 Ribosomal L25p family 5 90 1.3E-22 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 D521_1918 a172efa5c0a2b1974df2433ff137a43a 212 Gene3D G3DSA:2.40.240.10 1 93 4.7E-30 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_1918 a172efa5c0a2b1974df2433ff137a43a 212 Gene3D G3DSA:2.170.120.20 95 191 6.9E-25 T 14-10-2018 IPR037121 Ribosomal protein L25, C-terminal D521_1918 a172efa5c0a2b1974df2433ff137a43a 212 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 98 181 1.4E-27 T 14-10-2018 IPR020057 Ribosomal protein L25, beta domain D521_1918 a172efa5c0a2b1974df2433ff137a43a 212 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 172 3.0E-41 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 D521_1918 a172efa5c0a2b1974df2433ff137a43a 212 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 184 30.372 T 14-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 D521_1918 a172efa5c0a2b1974df2433ff137a43a 212 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 93 6.0E-41 T 14-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 D521_0013 6d01fc13a08da8ba0147a3a45a4ead83 256 Pfam PF13614 AAA domain 3 177 1.5E-63 T 14-10-2018 IPR025669 AAA domain D521_0013 6d01fc13a08da8ba0147a3a45a4ead83 256 Gene3D G3DSA:3.40.50.300 1 256 6.1E-77 T 14-10-2018 D521_0013 6d01fc13a08da8ba0147a3a45a4ead83 256 SUPERFAMILY SSF52540 1 254 2.6E-63 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0054 a72bfa96afe658daf4ab47c7cbd5069c 104 Gene3D G3DSA:3.30.70.330 5 103 2.5E-32 T 14-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily D521_0054 a72bfa96afe658daf4ab47c7cbd5069c 104 SUPERFAMILY SSF54189 9 97 2.27E-28 T 14-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0054 a72bfa96afe658daf4ab47c7cbd5069c 104 Pfam PF00276 Ribosomal protein L23 13 99 2.7E-30 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 D521_0054 a72bfa96afe658daf4ab47c7cbd5069c 104 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 12 102 21.279 T 14-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 D521_1752 4e268e6628bf33237186f11521747d2f 186 Pfam PF01025 GrpE 27 183 2.5E-48 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 D521_1752 4e268e6628bf33237186f11521747d2f 186 SUPERFAMILY SSF51064 132 184 1.44E-15 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 D521_1752 4e268e6628bf33237186f11521747d2f 186 Gene3D G3DSA:2.30.22.10 129 184 3.0E-19 T 14-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 D521_1752 4e268e6628bf33237186f11521747d2f 186 SUPERFAMILY SSF58014 35 126 3.79E-23 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 D521_1752 4e268e6628bf33237186f11521747d2f 186 PRINTS PR00773 GrpE protein signature 56 72 5.9E-23 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 D521_1752 4e268e6628bf33237186f11521747d2f 186 PRINTS PR00773 GrpE protein signature 137 152 5.9E-23 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 D521_1752 4e268e6628bf33237186f11521747d2f 186 PRINTS PR00773 GrpE protein signature 84 99 5.9E-23 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 D521_1752 4e268e6628bf33237186f11521747d2f 186 PRINTS PR00773 GrpE protein signature 163 182 5.9E-23 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 D521_1752 4e268e6628bf33237186f11521747d2f 186 Gene3D G3DSA:3.90.20.20 26 126 1.6E-24 T 14-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 D521_1752 4e268e6628bf33237186f11521747d2f 186 ProSitePatterns PS01071 grpE protein signature. 140 182 - T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 D521_1752 4e268e6628bf33237186f11521747d2f 186 Hamap MF_01151 Protein GrpE [grpE]. 3 184 19.143 T 14-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 D521_0236 6e94412d442fca54992820e3c495836c 166 Gene3D G3DSA:3.30.160.150 30 164 7.3E-31 T 14-10-2018 D521_0236 6e94412d442fca54992820e3c495836c 166 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 1 159 18.965 T 14-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 D521_0236 6e94412d442fca54992820e3c495836c 166 Pfam PF04390 Lipopolysaccharide-assembly 36 153 7.7E-11 T 14-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 D521_0296 a388f36b8d9a4eaebdcacb5d2bf3643a 92 Gene3D G3DSA:3.30.2310.20 2 90 3.6E-5 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily D521_0296 a388f36b8d9a4eaebdcacb5d2bf3643a 92 Pfam PF15781 ParE-like toxin of type II bacterial toxin-antitoxin system 4 88 8.5E-30 T 14-10-2018 IPR031552 Type II bacterial toxin-antitoxin system, ParE-like toxin D521_0466 1cb51cef0703107e391fa55f575d0777 176 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 29 160 4.2E-29 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 D521_0466 1cb51cef0703107e391fa55f575d0777 176 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 11 150 2.3E-34 T 14-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 D521_0466 1cb51cef0703107e391fa55f575d0777 176 SUPERFAMILY SSF52540 41 145 3.06E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0466 1cb51cef0703107e391fa55f575d0777 176 Gene3D G3DSA:3.40.50.300 4 174 3.0E-39 T 14-10-2018 D521_1635 30fe4d2de0c67a8a8956df37c20ac3f3 346 SUPERFAMILY SSF55874 108 157 7.73E-9 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1635 30fe4d2de0c67a8a8956df37c20ac3f3 346 Gene3D G3DSA:3.30.565.10 87 190 2.7E-9 T 14-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily D521_1635 30fe4d2de0c67a8a8956df37c20ac3f3 346 Pfam PF14213 STAS-like domain of unknown function (DUF4325) 280 335 1.3E-13 T 14-10-2018 IPR025474 Domain of unknown function DUF4325 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 Pfam PF00085 Thioredoxin 38 137 1.8E-28 T 14-10-2018 IPR013766 Thioredoxin domain GO:0045454 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 Gene3D G3DSA:3.40.30.10 35 140 6.0E-31 T 14-10-2018 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 TIGRFAM TIGR01068 thioredoxin: thioredoxin 40 138 4.3E-33 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 ProSitePatterns PS00194 Thioredoxin family active site. 56 74 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 Gene3D G3DSA:2.20.28.140 1 34 7.3E-10 T 14-10-2018 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 PIRSF PIRSF000077 34 139 7.5E-31 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 PIRSF PIRSF000077 23 30 2100.0 T 14-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 PRINTS PR00421 Thioredoxin family signature 63 72 7.2E-8 T 14-10-2018 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 PRINTS PR00421 Thioredoxin family signature 55 63 7.2E-8 T 14-10-2018 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 PRINTS PR00421 Thioredoxin family signature 103 114 7.2E-8 T 14-10-2018 D521_1055 3ca046d66d33d9884c08aef973b17c49 140 SUPERFAMILY SSF52833 36 139 5.39E-34 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 239 260 9.6E-63 T 14-10-2018 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 261 287 9.6E-63 T 14-10-2018 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 329 341 9.6E-63 T 14-10-2018 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 119 139 9.6E-63 T 14-10-2018 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 434 453 9.6E-63 T 14-10-2018 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 166 187 9.6E-63 T 14-10-2018 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 91 116 9.6E-63 T 14-10-2018 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 279 301 3.4E-15 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 496 517 3.4E-15 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 67 91 3.4E-15 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 45 64 3.4E-15 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 93 113 3.4E-15 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 433 455 3.4E-15 T 14-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 11 678 2.3E-238 T 14-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 Pfam PF00361 Proton-conducting membrane transporter 142 425 4.0E-86 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0757 c6e791cdd82f7d8898dbd0afa863f666 686 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 73 130 1.1E-26 T 14-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0522 96fbb7594482598fb33029e0d2e2e8a0 269 SUPERFAMILY SSF69618 4 262 2.09E-33 T 14-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0522 96fbb7594482598fb33029e0d2e2e8a0 269 Gene3D G3DSA:3.40.50.10090 6 256 3.9E-51 T 14-10-2018 D521_0522 96fbb7594482598fb33029e0d2e2e8a0 269 Gene3D G3DSA:3.40.50.10090 45 189 3.9E-51 T 14-10-2018 D521_0522 96fbb7594482598fb33029e0d2e2e8a0 269 Pfam PF02602 Uroporphyrinogen-III synthase HemD 38 260 1.5E-19 T 14-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 D521_0352 a8a20889dd2169447c7f03825b21d337 642 Pfam PF02653 Branched-chain amino acid transport system / permease component 30 274 6.4E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 D521_0352 a8a20889dd2169447c7f03825b21d337 642 Pfam PF00005 ABC transporter 410 570 2.8E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0352 a8a20889dd2169447c7f03825b21d337 642 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 619 641 4.1E-9 T 14-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal D521_0352 a8a20889dd2169447c7f03825b21d337 642 Gene3D G3DSA:3.40.50.300 389 642 5.3E-61 T 14-10-2018 D521_0352 a8a20889dd2169447c7f03825b21d337 642 SMART SM00382 419 627 2.9E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0352 a8a20889dd2169447c7f03825b21d337 642 SUPERFAMILY SSF52540 394 640 9.55E-61 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0465 0ec0624f6d1111c653de41e42fe96647 445 Gene3D G3DSA:3.40.630.40 201 443 1.4E-79 T 14-10-2018 D521_0465 0ec0624f6d1111c653de41e42fe96647 445 Gene3D G3DSA:2.60.40.3500 29 147 1.4E-32 T 14-10-2018 D521_0465 0ec0624f6d1111c653de41e42fe96647 445 SMART SM00646 275 430 1.3E-59 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 D521_0465 0ec0624f6d1111c653de41e42fe96647 445 SUPERFAMILY SSF53187 213 433 3.45E-53 T 14-10-2018 D521_0465 0ec0624f6d1111c653de41e42fe96647 445 Pfam PF11741 AMIN domain 41 144 1.9E-26 T 14-10-2018 IPR021731 AMIN domain D521_0465 0ec0624f6d1111c653de41e42fe96647 445 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 215 430 1.9E-48 T 14-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 D521_1888 8729edf31c8c7500fc8e6a3d366ad902 217 Pfam PF04367 Protein of unknown function (DUF502) 64 169 2.4E-33 T 14-10-2018 IPR007462 Protein of unknown function DUF502 D521_0708 a0aba32f85ae0647d15936383074b274 129 Pfam PF09626 Dihaem cytochrome c 9 119 2.9E-39 T 14-10-2018 IPR018588 Dihaem cytochrome c D521_0708 a0aba32f85ae0647d15936383074b274 129 SUPERFAMILY SSF48695 5 117 1.2E-6 T 14-10-2018 IPR036280 Multiheme cytochrome superfamily D521_1801 fe3ab982f0268ea35012640ee609bd56 375 SUPERFAMILY SSF53383 10 374 5.25E-67 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_1801 fe3ab982f0268ea35012640ee609bd56 375 Gene3D G3DSA:3.40.640.10 39 270 6.4E-114 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_1801 fe3ab982f0268ea35012640ee609bd56 375 Pfam PF00266 Aminotransferase class-V 22 306 2.8E-9 T 14-10-2018 IPR000192 Aminotransferase class V domain D521_1801 fe3ab982f0268ea35012640ee609bd56 375 Gene3D G3DSA:3.90.1150.10 271 370 6.4E-114 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_1801 fe3ab982f0268ea35012640ee609bd56 375 PIRSF PIRSF000524 18 375 5.9E-37 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 D521_1978 ecf44a36babc39a697fcdf4527b49fa0 354 Pfam PF02574 Homocysteine S-methyltransferase 25 337 4.6E-80 T 14-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 D521_1978 ecf44a36babc39a697fcdf4527b49fa0 354 PIRSF PIRSF037505 65 352 2.4E-7 T 14-10-2018 IPR017226 Betaine-homocysteine S-methyltransferase, BHMT GO:0005737|GO:0008270|GO:0009086|GO:0047150 Reactome: R-HSA-1614635 D521_1978 ecf44a36babc39a697fcdf4527b49fa0 354 SUPERFAMILY SSF82282 16 345 5.76E-99 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 D521_1978 ecf44a36babc39a697fcdf4527b49fa0 354 Gene3D G3DSA:3.20.20.330 10 351 3.7E-124 T 14-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 D521_1805 d8aa2c8df425c77cb887cf0ede1bf7cd 481 Gene3D G3DSA:3.40.710.10 247 467 2.6E-51 T 14-10-2018 D521_1805 d8aa2c8df425c77cb887cf0ede1bf7cd 481 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 38 469 9.2E-78 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 D521_1805 d8aa2c8df425c77cb887cf0ede1bf7cd 481 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 51 70 1.8E-22 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 D521_1805 d8aa2c8df425c77cb887cf0ede1bf7cd 481 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 361 375 1.8E-22 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 D521_1805 d8aa2c8df425c77cb887cf0ede1bf7cd 481 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 430 443 1.8E-22 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 D521_1805 d8aa2c8df425c77cb887cf0ede1bf7cd 481 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 288 310 1.8E-22 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 D521_1805 d8aa2c8df425c77cb887cf0ede1bf7cd 481 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 346 360 1.8E-22 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 D521_1805 d8aa2c8df425c77cb887cf0ede1bf7cd 481 SUPERFAMILY SSF56601 38 472 4.23E-80 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like D521_1805 d8aa2c8df425c77cb887cf0ede1bf7cd 481 Gene3D G3DSA:3.50.80.20 75 163 1.0E-20 T 14-10-2018 D521_1805 d8aa2c8df425c77cb887cf0ede1bf7cd 481 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 43 452 1.4E-58 T 14-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 D521_1098 667789e6bb63f4620c0829e38878349f 131 Gene3D G3DSA:1.10.260.40 30 113 2.4E-5 T 14-10-2018 D521_1144 f9c241d9e7d08018d0e0a5702b4a5a10 171 SUPERFAMILY SSF81324 36 158 3.14E-5 T 14-10-2018 D521_0733 6e1678ae70a312060b0ba97a40abe219 595 SUPERFAMILY SSF52467 212 386 7.2E-63 T 14-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily D521_0733 6e1678ae70a312060b0ba97a40abe219 595 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 219 353 8.6E-45 T 14-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 D521_0733 6e1678ae70a312060b0ba97a40abe219 595 SUPERFAMILY SSF52518 397 590 9.51E-69 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0733 6e1678ae70a312060b0ba97a40abe219 595 SUPERFAMILY SSF52518 28 208 2.27E-64 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0733 6e1678ae70a312060b0ba97a40abe219 595 Gene3D G3DSA:3.40.50.970 387 590 1.3E-65 T 14-10-2018 D521_0733 6e1678ae70a312060b0ba97a40abe219 595 Gene3D G3DSA:3.40.50.1220 213 384 1.3E-61 T 14-10-2018 D521_0733 6e1678ae70a312060b0ba97a40abe219 595 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 418 566 8.3E-50 T 14-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 D521_0733 6e1678ae70a312060b0ba97a40abe219 595 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 29 589 4.8E-254 T 14-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 D521_0733 6e1678ae70a312060b0ba97a40abe219 595 Gene3D G3DSA:3.40.50.970 21 203 4.0E-70 T 14-10-2018 D521_0733 6e1678ae70a312060b0ba97a40abe219 595 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 31 193 2.3E-57 T 14-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 D521_1944 69e1d0f46ee68fe09be212ea88f344f7 84 Pfam PF00462 Glutaredoxin 4 64 2.2E-17 T 14-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 D521_1944 69e1d0f46ee68fe09be212ea88f344f7 84 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 14-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 D521_1944 69e1d0f46ee68fe09be212ea88f344f7 84 SUPERFAMILY SSF52833 1 83 2.4E-25 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1944 69e1d0f46ee68fe09be212ea88f344f7 84 PRINTS PR00160 Glutaredoxin signature 61 74 5.9E-15 T 14-10-2018 IPR014025 Glutaredoxin subgroup D521_1944 69e1d0f46ee68fe09be212ea88f344f7 84 PRINTS PR00160 Glutaredoxin signature 47 60 5.9E-15 T 14-10-2018 IPR014025 Glutaredoxin subgroup D521_1944 69e1d0f46ee68fe09be212ea88f344f7 84 PRINTS PR00160 Glutaredoxin signature 4 22 5.9E-15 T 14-10-2018 IPR014025 Glutaredoxin subgroup D521_1944 69e1d0f46ee68fe09be212ea88f344f7 84 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 83 2.3E-34 T 14-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 D521_1944 69e1d0f46ee68fe09be212ea88f344f7 84 Gene3D G3DSA:3.40.30.10 1 84 4.4E-25 T 14-10-2018 D521_0905 38277f59036048939cb8a28df9f31952 212 Gene3D G3DSA:1.10.10.10 8 74 2.3E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0905 38277f59036048939cb8a28df9f31952 212 Gene3D G3DSA:1.20.120.530 75 211 1.7E-29 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal D521_0905 38277f59036048939cb8a28df9f31952 212 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 32 46 2.1E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0905 38277f59036048939cb8a28df9f31952 212 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 46 62 2.1E-5 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0905 38277f59036048939cb8a28df9f31952 212 SMART SM00345 14 72 3.2E-15 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0905 38277f59036048939cb8a28df9f31952 212 SUPERFAMILY SSF46785 7 76 1.94E-20 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0905 38277f59036048939cb8a28df9f31952 212 SUPERFAMILY SSF48008 78 209 6.8E-27 T 14-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal D521_0905 38277f59036048939cb8a28df9f31952 212 SMART SM00895 82 206 2.0E-21 T 14-10-2018 IPR011711 GntR, C-terminal D521_0905 38277f59036048939cb8a28df9f31952 212 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.7E-17 T 14-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 D521_0905 38277f59036048939cb8a28df9f31952 212 Pfam PF07729 FCD domain 82 206 2.8E-28 T 14-10-2018 IPR011711 GntR, C-terminal D521_0005 f1bb6c1af2e4295d0f49daf2e3946b58 74 Pfam PF12512 Protein of unknown function (DUF3717) 4 68 6.3E-27 T 14-10-2018 IPR022191 Protein of unknown function DUF3717 D521_0072 14846e226ea8b9c972c81f37082391ef 445 ProSitePatterns PS00755 Protein secY signature 1. 78 97 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 D521_0072 14846e226ea8b9c972c81f37082391ef 445 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 22 432 6.1E-127 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 D521_0072 14846e226ea8b9c972c81f37082391ef 445 ProSitePatterns PS00756 Protein secY signature 2. 172 189 - T 14-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 D521_0072 14846e226ea8b9c972c81f37082391ef 445 SUPERFAMILY SSF103491 11 426 2.22E-130 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 D521_0072 14846e226ea8b9c972c81f37082391ef 445 PRINTS PR00303 Preprotein translocase SecY subunit signature 25 43 4.5E-93 T 14-10-2018 D521_0072 14846e226ea8b9c972c81f37082391ef 445 PRINTS PR00303 Preprotein translocase SecY subunit signature 179 202 4.5E-93 T 14-10-2018 D521_0072 14846e226ea8b9c972c81f37082391ef 445 PRINTS PR00303 Preprotein translocase SecY subunit signature 318 340 4.5E-93 T 14-10-2018 D521_0072 14846e226ea8b9c972c81f37082391ef 445 PRINTS PR00303 Preprotein translocase SecY subunit signature 77 97 4.5E-93 T 14-10-2018 D521_0072 14846e226ea8b9c972c81f37082391ef 445 PRINTS PR00303 Preprotein translocase SecY subunit signature 153 178 4.5E-93 T 14-10-2018 D521_0072 14846e226ea8b9c972c81f37082391ef 445 PRINTS PR00303 Preprotein translocase SecY subunit signature 405 423 4.5E-93 T 14-10-2018 D521_0072 14846e226ea8b9c972c81f37082391ef 445 PRINTS PR00303 Preprotein translocase SecY subunit signature 118 141 4.5E-93 T 14-10-2018 D521_0072 14846e226ea8b9c972c81f37082391ef 445 PRINTS PR00303 Preprotein translocase SecY subunit signature 373 391 4.5E-93 T 14-10-2018 D521_0072 14846e226ea8b9c972c81f37082391ef 445 PRINTS PR00303 Preprotein translocase SecY subunit signature 271 290 4.5E-93 T 14-10-2018 D521_0072 14846e226ea8b9c972c81f37082391ef 445 Pfam PF00344 SecY translocase 78 420 1.5E-115 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 D521_0072 14846e226ea8b9c972c81f37082391ef 445 Gene3D G3DSA:1.10.3370.10 10 432 4.6E-158 T 14-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 D521_0072 14846e226ea8b9c972c81f37082391ef 445 Hamap MF_01465 Protein translocase subunit SecY [secY]. 12 436 28.992 T 14-10-2018 IPR026593 Protein translocase subunit SecY D521_0072 14846e226ea8b9c972c81f37082391ef 445 PIRSF PIRSF004557 6 443 2.8E-120 T 14-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 D521_1031 ff1cd5204e1455014e9370b766203139 346 SUPERFAMILY SSF56601 1 331 4.72E-56 T 14-10-2018 IPR012338 Beta-lactamase/transpeptidase-like D521_1031 ff1cd5204e1455014e9370b766203139 346 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 172 189 1.3E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 D521_1031 ff1cd5204e1455014e9370b766203139 346 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 199 212 1.3E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 D521_1031 ff1cd5204e1455014e9370b766203139 346 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 124 135 1.3E-11 T 14-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 D521_1031 ff1cd5204e1455014e9370b766203139 346 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 91 314 5.5E-49 T 14-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 D521_1031 ff1cd5204e1455014e9370b766203139 346 Gene3D G3DSA:3.40.710.10 81 341 1.5E-62 T 14-10-2018 D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 SMART SM00448 13 127 8.3E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 SUPERFAMILY SSF52172 15 153 3.7E-30 T 14-10-2018 IPR011006 CheY-like superfamily D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 SUPERFAMILY SSF46894 143 209 2.72E-20 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 SMART SM00421 151 208 2.0E-21 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 1.1E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 Gene3D G3DSA:1.10.10.10 146 211 1.9E-21 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 2.8E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 2.8E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 2.8E-13 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 Gene3D G3DSA:3.40.50.2300 8 143 4.9E-46 T 14-10-2018 D521_1038 8cdf33ad4e92770afda38b742d2966e5 215 Pfam PF00072 Response regulator receiver domain 15 126 4.7E-25 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_0563 4269d742c58dfc7a2f516c5e0739765b 72 Pfam PF04325 Protein of unknown function (DUF465) 19 65 3.1E-17 T 14-10-2018 IPR007420 Protein of unknown function DUF465 D521_0563 4269d742c58dfc7a2f516c5e0739765b 72 Gene3D G3DSA:1.20.58.660 1 72 6.3E-27 T 14-10-2018 D521_1032 0c0fbd60c0cdb42c79e1406309ef5a0e 295 Pfam PF00892 EamA-like transporter family 12 137 6.3E-13 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 D521_1032 0c0fbd60c0cdb42c79e1406309ef5a0e 295 Pfam PF00892 EamA-like transporter family 150 283 8.0E-10 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 D521_1032 0c0fbd60c0cdb42c79e1406309ef5a0e 295 SUPERFAMILY SSF103481 43 138 7.85E-9 T 14-10-2018 D521_1032 0c0fbd60c0cdb42c79e1406309ef5a0e 295 SUPERFAMILY SSF103481 191 286 1.7E-12 T 14-10-2018 D521_1789 59d5dd111f888139fc39e548d435b7e1 93 Gene3D G3DSA:1.20.58.1000 1 93 9.9E-29 T 14-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily D521_1789 59d5dd111f888139fc39e548d435b7e1 93 Pfam PF02583 Metal-sensitive transcriptional repressor 7 81 3.1E-21 T 14-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 D521_0473 df7a7881000b970555c30ffcb3125a0d 135 Pfam PF03928 Haem-degrading 8 131 4.7E-28 T 14-10-2018 IPR005624 Haem-degrading D521_0473 df7a7881000b970555c30ffcb3125a0d 135 Gene3D G3DSA:3.30.450.150 1 135 4.3E-36 T 14-10-2018 IPR038084 GlcG-like domain superfamily D521_0473 df7a7881000b970555c30ffcb3125a0d 135 SUPERFAMILY SSF143744 4 134 3.92E-34 T 14-10-2018 IPR038084 GlcG-like domain superfamily D521_0116 aa9495616000308625a8d2fe83fcb761 158 Pfam PF02416 mttA/Hcf106 family 4 34 1.3E-6 T 14-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 D521_0116 aa9495616000308625a8d2fe83fcb761 158 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 7.5E-13 T 14-10-2018 D521_0116 aa9495616000308625a8d2fe83fcb761 158 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 7.5E-13 T 14-10-2018 D521_0116 aa9495616000308625a8d2fe83fcb761 158 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 7.5E-13 T 14-10-2018 D521_0116 aa9495616000308625a8d2fe83fcb761 158 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 158 14.546 T 14-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 D521_0116 aa9495616000308625a8d2fe83fcb761 158 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 3 78 2.1E-18 T 14-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 D521_0953 e6fbe71265f57e506d58992920100380 262 PIRSF PIRSF005902 1 260 6.7E-80 T 14-10-2018 IPR001130 TatD family GO:0016788 D521_0953 e6fbe71265f57e506d58992920100380 262 SUPERFAMILY SSF51556 2 258 1.23E-86 T 14-10-2018 IPR032466 Metal-dependent hydrolase D521_0953 e6fbe71265f57e506d58992920100380 262 Pfam PF01026 TatD related DNase 3 256 2.6E-76 T 14-10-2018 IPR001130 TatD family GO:0016788 D521_0953 e6fbe71265f57e506d58992920100380 262 Gene3D G3DSA:3.20.20.140 1 261 3.1E-89 T 14-10-2018 D521_0953 e6fbe71265f57e506d58992920100380 262 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 257 7.8E-81 T 14-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 D521_0953 e6fbe71265f57e506d58992920100380 262 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 D521_0951 f8b65ed9f3df6d49702c97bd76cf1842 158 Pfam PF07885 Ion channel 76 134 2.5E-5 T 14-10-2018 IPR013099 Potassium channel domain D521_0951 f8b65ed9f3df6d49702c97bd76cf1842 158 SUPERFAMILY SSF81324 53 141 1.57E-5 T 14-10-2018 D521_0643 5f0334c2f5fa14496c504f9bd3506cd8 453 SUPERFAMILY SSF52540 82 418 3.88E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0643 5f0334c2f5fa14496c504f9bd3506cd8 453 Pfam PF00437 Type II/IV secretion system protein 100 376 1.0E-84 T 14-10-2018 IPR001482 Type II/IV secretion system protein D521_0643 5f0334c2f5fa14496c504f9bd3506cd8 453 Gene3D G3DSA:3.40.50.300 197 416 2.5E-72 T 14-10-2018 D521_0643 5f0334c2f5fa14496c504f9bd3506cd8 453 Gene3D G3DSA:3.30.450.380 32 195 6.3E-44 T 14-10-2018 D521_0218 eaebd6ba098881b8b2435271190ae6ec 662 SUPERFAMILY SSF50249 231 588 4.51E-70 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_0218 eaebd6ba098881b8b2435271190ae6ec 662 Pfam PF00773 RNB domain 249 490 1.4E-35 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 D521_0218 eaebd6ba098881b8b2435271190ae6ec 662 SMART SM00955 245 539 2.9E-60 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 D521_0218 eaebd6ba098881b8b2435271190ae6ec 662 Pfam PF00773 RNB domain 497 536 7.9E-10 T 14-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 D521_0218 eaebd6ba098881b8b2435271190ae6ec 662 ProSitePatterns PS01175 Ribonuclease II family signature. 506 530 - T 14-10-2018 IPR022966 Ribonuclease II/R, conserved site D521_1826 2f0e139e7c118afba13fd33c49041739 235 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 14 192 2.0E-66 T 14-10-2018 IPR022301 Integral membrane protein YjbE D521_1826 2f0e139e7c118afba13fd33c49041739 235 Pfam PF03741 Integral membrane protein TerC family 17 191 6.6E-45 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 D521_1229 bb231e66af1d799cdd828c82f1c1865a 470 PIRSF PIRSF005522 1 470 1.1E-230 T 14-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 D521_1229 bb231e66af1d799cdd828c82f1c1865a 470 Gene3D G3DSA:3.40.50.11290 209 306 1.0E-43 T 14-10-2018 D521_1229 bb231e66af1d799cdd828c82f1c1865a 470 Pfam PF14403 Circularly permuted ATP-grasp type 2 71 446 6.1E-163 T 14-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 D521_1229 bb231e66af1d799cdd828c82f1c1865a 470 Gene3D G3DSA:3.30.1490.270 343 403 1.8E-24 T 14-10-2018 D521_1229 bb231e66af1d799cdd828c82f1c1865a 470 SUPERFAMILY SSF56059 14 461 3.22E-64 T 14-10-2018 D521_1726 1e23162c848efb5b9c5d69057786292f 164 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 5 159 16.539 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 D521_1726 1e23162c848efb5b9c5d69057786292f 164 ProSitePatterns PS00855 Signal peptidases II signature. 101 113 - T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 D521_1726 1e23162c848efb5b9c5d69057786292f 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 51 59 2.4E-18 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 D521_1726 1e23162c848efb5b9c5d69057786292f 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 134 150 2.4E-18 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 D521_1726 1e23162c848efb5b9c5d69057786292f 164 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 98 113 2.4E-18 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 D521_1726 1e23162c848efb5b9c5d69057786292f 164 TIGRFAM TIGR00077 lspA: signal peptidase II 5 159 2.9E-38 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 D521_1726 1e23162c848efb5b9c5d69057786292f 164 Pfam PF01252 Signal peptidase (SPase) II 13 151 5.3E-39 T 14-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 D521_0086 57c5324c08a37090c8738af16c985166 142 TIGRFAM TIGR03421 FeS_CyaY: iron donor protein CyaY 27 135 4.1E-29 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_0086 57c5324c08a37090c8738af16c985166 142 Pfam PF01491 Frataxin-like domain 26 133 2.5E-23 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_0086 57c5324c08a37090c8738af16c985166 142 Gene3D G3DSA:3.30.920.10 23 139 9.2E-33 T 14-10-2018 IPR036524 Frataxin/CyaY superfamily GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_0086 57c5324c08a37090c8738af16c985166 142 Hamap MF_00142 Iron-sulfur cluster assembly protein CyaY [cyaY]. 26 137 20.672 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_0086 57c5324c08a37090c8738af16c985166 142 ProSitePatterns PS01344 Frataxin family signature. 78 92 - T 14-10-2018 IPR020895 Frataxin conserved site Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_0086 57c5324c08a37090c8738af16c985166 142 SMART SM01219 26 138 1.3E-39 T 14-10-2018 IPR002908 Frataxin/CyaY GO:0008199|GO:0016226 Reactome: R-HSA-1268020|Reactome: R-HSA-1362409 D521_0086 57c5324c08a37090c8738af16c985166 142 SUPERFAMILY SSF55387 20 133 1.05E-27 T 14-10-2018 D521_1029 1e98dc58b71f23bd82e7b70da8bd64fc 343 SUPERFAMILY SSF51395 5 337 1.56E-100 T 14-10-2018 D521_1029 1e98dc58b71f23bd82e7b70da8bd64fc 343 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 4 341 48.673 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 D521_1029 1e98dc58b71f23bd82e7b70da8bd64fc 343 Pfam PF01180 Dihydroorotate dehydrogenase 50 337 5.7E-90 T 14-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 D521_1029 1e98dc58b71f23bd82e7b70da8bd64fc 343 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 82 101 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 D521_1029 1e98dc58b71f23bd82e7b70da8bd64fc 343 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 5 339 9.4E-124 T 14-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 D521_1029 1e98dc58b71f23bd82e7b70da8bd64fc 343 Gene3D G3DSA:3.20.20.70 4 339 3.6E-127 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1029 1e98dc58b71f23bd82e7b70da8bd64fc 343 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 297 317 - T 14-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 D521_1029 1e98dc58b71f23bd82e7b70da8bd64fc 343 PIRSF PIRSF000164 18 343 4.4E-93 T 14-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 D521_0805 5422b3ab75487c21a6af06605d1a41c8 133 Gene3D G3DSA:1.10.3830.10 13 131 3.1E-34 T 14-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 D521_0805 5422b3ab75487c21a6af06605d1a41c8 133 Pfam PF01219 Prokaryotic diacylglycerol kinase 26 126 1.2E-32 T 14-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 D521_0312 40b00091180efd72629e07fa444f439b 342 Gene3D G3DSA:3.40.50.11660 194 313 1.7E-23 T 14-10-2018 IPR038577 GT10-like superfamily D521_0312 40b00091180efd72629e07fa444f439b 342 SUPERFAMILY SSF53756 78 308 8.16E-25 T 14-10-2018 D521_0312 40b00091180efd72629e07fa444f439b 342 Pfam PF00852 Glycosyltransferase family 10 (fucosyltransferase) C-term 222 296 2.5E-13 T 14-10-2018 IPR001503 Glycosyl transferase family 10 GO:0006486|GO:0008417|GO:0016020 D521_1040 1b4830d9143663e97e639d87a962f96b 710 Gene3D G3DSA:1.10.1370.10 154 634 1.2E-245 T 14-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 D521_1040 1b4830d9143663e97e639d87a962f96b 710 Pfam PF01432 Peptidase family M3 236 705 9.8E-136 T 14-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 D521_1040 1b4830d9143663e97e639d87a962f96b 710 SUPERFAMILY SSF55486 22 706 3.17E-181 T 14-10-2018 D521_1040 1b4830d9143663e97e639d87a962f96b 710 Gene3D G3DSA:1.10.1370.40 28 704 1.2E-245 T 14-10-2018 D521_1096 67fa652c77503fb06a5a630cd5b95dda 126 ProSitePatterns PS00892 HIT domain signature. 83 101 - T 14-10-2018 IPR019808 Histidine triad, conserved site D521_1096 67fa652c77503fb06a5a630cd5b95dda 126 SUPERFAMILY SSF54197 2 113 1.56E-39 T 14-10-2018 IPR036265 HIT-like superfamily D521_1096 67fa652c77503fb06a5a630cd5b95dda 126 Gene3D G3DSA:3.30.428.10 1 123 3.1E-40 T 14-10-2018 IPR036265 HIT-like superfamily D521_1096 67fa652c77503fb06a5a630cd5b95dda 126 PRINTS PR00332 Histidine triad family signature 23 41 3.1E-6 T 14-10-2018 IPR001310 Histidine triad (HIT) protein D521_1096 67fa652c77503fb06a5a630cd5b95dda 126 PRINTS PR00332 Histidine triad family signature 90 100 3.1E-6 T 14-10-2018 IPR001310 Histidine triad (HIT) protein D521_1096 67fa652c77503fb06a5a630cd5b95dda 126 Pfam PF01230 HIT domain 22 104 4.1E-22 T 14-10-2018 IPR001310 Histidine triad (HIT) protein D521_0998 7dffe2d9f96275a04d39f65d854320a5 397 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 56 380 5.3E-48 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme D521_0998 7dffe2d9f96275a04d39f65d854320a5 397 Gene3D G3DSA:3.40.50.1100 56 386 4.6E-187 T 14-10-2018 D521_0998 7dffe2d9f96275a04d39f65d854320a5 397 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 9 392 2.9E-192 T 14-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 D521_0998 7dffe2d9f96275a04d39f65d854320a5 397 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 393 52.679 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 D521_0998 7dffe2d9f96275a04d39f65d854320a5 397 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 14-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 D521_0998 7dffe2d9f96275a04d39f65d854320a5 397 Gene3D G3DSA:3.40.50.1100 12 208 4.6E-187 T 14-10-2018 D521_0998 7dffe2d9f96275a04d39f65d854320a5 397 SUPERFAMILY SSF53686 5 390 1.14E-151 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme D521_0998 7dffe2d9f96275a04d39f65d854320a5 397 PIRSF PIRSF001413 2 397 1.3E-164 T 14-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 D521_0270 8c929551defd8a4e8d8796ce3864115e 371 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 105 5.2E-19 T 14-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain D521_0270 8c929551defd8a4e8d8796ce3864115e 371 SUPERFAMILY SSF53597 151 366 1.07E-57 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 D521_0270 8c929551defd8a4e8d8796ce3864115e 371 SUPERFAMILY SSF53927 6 150 1.51E-44 T 14-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 D521_0270 8c929551defd8a4e8d8796ce3864115e 371 PIRSF PIRSF006769 1 370 3.0E-117 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 D521_0270 8c929551defd8a4e8d8796ce3864115e 371 Gene3D G3DSA:3.40.140.10 2 146 2.6E-46 T 14-10-2018 D521_0270 8c929551defd8a4e8d8796ce3864115e 371 Pfam PF01872 RibD C-terminal domain 153 334 2.2E-42 T 14-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 D521_0270 8c929551defd8a4e8d8796ce3864115e 371 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 152 366 1.4E-49 T 14-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 D521_0270 8c929551defd8a4e8d8796ce3864115e 371 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 94 - T 14-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 D521_0270 8c929551defd8a4e8d8796ce3864115e 371 Gene3D G3DSA:3.40.430.10 147 370 8.8E-66 T 14-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 D521_0270 8c929551defd8a4e8d8796ce3864115e 371 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 10 365 3.1E-99 T 14-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 D521_1885 ea94760b2b656596cb3153ed7e8f477d 607 ProSitePatterns PS00211 ABC transporters family signature. 503 517 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_1885 ea94760b2b656596cb3153ed7e8f477d 607 Gene3D G3DSA:1.20.1560.10 32 352 2.6E-121 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 D521_1885 ea94760b2b656596cb3153ed7e8f477d 607 Pfam PF00664 ABC transporter transmembrane region 40 314 2.2E-41 T 14-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 D521_1885 ea94760b2b656596cb3153ed7e8f477d 607 SUPERFAMILY SSF52540 362 601 1.25E-92 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1885 ea94760b2b656596cb3153ed7e8f477d 607 Pfam PF00005 ABC transporter 382 531 4.1E-35 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_1885 ea94760b2b656596cb3153ed7e8f477d 607 Gene3D G3DSA:3.40.50.300 358 607 3.1E-95 T 14-10-2018 D521_1885 ea94760b2b656596cb3153ed7e8f477d 607 SMART SM00382 391 583 1.1E-11 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1885 ea94760b2b656596cb3153ed7e8f477d 607 SUPERFAMILY SSF90123 26 350 2.35E-66 T 14-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 D521_0187 56537bb2b86192fa0e46cc1482101985 356 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 212 226 - T 14-10-2018 IPR001482 Type II/IV secretion system protein D521_0187 56537bb2b86192fa0e46cc1482101985 356 SUPERFAMILY SSF52540 2 323 8.06E-74 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0187 56537bb2b86192fa0e46cc1482101985 356 Gene3D G3DSA:3.30.450.90 1 116 2.0E-35 T 14-10-2018 D521_0187 56537bb2b86192fa0e46cc1482101985 356 Gene3D G3DSA:3.40.50.300 119 347 2.7E-79 T 14-10-2018 D521_0187 56537bb2b86192fa0e46cc1482101985 356 SMART SM00382 145 268 0.0046 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0187 56537bb2b86192fa0e46cc1482101985 356 Pfam PF00437 Type II/IV secretion system protein 18 284 1.6E-74 T 14-10-2018 IPR001482 Type II/IV secretion system protein D521_1941 b62ed0fef9e66162cfb988a674c8866d 156 PIRSF PIRSF029256 1 156 7.4E-64 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 D521_1941 b62ed0fef9e66162cfb988a674c8866d 156 Gene3D G3DSA:3.40.1280.10 1 156 1.3E-62 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal D521_1941 b62ed0fef9e66162cfb988a674c8866d 156 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 1 152 5.7E-59 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 D521_1941 b62ed0fef9e66162cfb988a674c8866d 156 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 153 32.024 T 14-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 D521_1941 b62ed0fef9e66162cfb988a674c8866d 156 SUPERFAMILY SSF75217 1 151 1.57E-38 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases D521_1941 b62ed0fef9e66162cfb988a674c8866d 156 Pfam PF00588 SpoU rRNA Methylase family 2 144 1.5E-30 T 14-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 D521_0024 8f7adb750e604079570870c8b4363c71 369 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 D521_0024 8f7adb750e604079570870c8b4363c71 369 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 4 363 45.7 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 D521_0024 8f7adb750e604079570870c8b4363c71 369 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 20 29 - T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 D521_0024 8f7adb750e604079570870c8b4363c71 369 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 7 359 1.2E-111 T 14-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 D521_0024 8f7adb750e604079570870c8b4363c71 369 SUPERFAMILY SSF51726 2 361 2.62E-96 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 D521_0024 8f7adb750e604079570870c8b4363c71 369 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 4 359 1.1E-119 T 14-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 D521_0024 8f7adb750e604079570870c8b4363c71 369 Gene3D G3DSA:3.20.20.210 1 369 2.6E-133 T 14-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 D521_0426 a92bde56c081da89b1bf5ff97135a353 507 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 492 7.0E-291 T 14-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 D521_0426 a92bde56c081da89b1bf5ff97135a353 507 Pfam PF13247 4Fe-4S dicluster domain 175 271 2.6E-37 T 14-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain D521_0426 a92bde56c081da89b1bf5ff97135a353 507 SUPERFAMILY SSF54862 1 491 1.26E-179 T 14-10-2018 D521_0426 a92bde56c081da89b1bf5ff97135a353 507 Gene3D G3DSA:1.10.3650.10 358 434 5.2E-27 T 14-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 D521_0426 a92bde56c081da89b1bf5ff97135a353 507 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 436 2.6E-27 T 14-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 D521_0426 a92bde56c081da89b1bf5ff97135a353 507 Gene3D G3DSA:3.30.70.20 1 303 1.0E-102 T 14-10-2018 D521_1884 ee24d376d1b0fb61c1f0c3b81ff3da69 440 Gene3D G3DSA:3.40.50.10180 38 271 6.5E-130 T 14-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 D521_1884 ee24d376d1b0fb61c1f0c3b81ff3da69 440 Pfam PF13660 Domain of unknown function (DUF4147) 8 244 2.1E-74 T 14-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 D521_1884 ee24d376d1b0fb61c1f0c3b81ff3da69 440 SUPERFAMILY SSF82544 5 438 8.5E-126 T 14-10-2018 D521_1884 ee24d376d1b0fb61c1f0c3b81ff3da69 440 Gene3D G3DSA:3.40.1480.10 272 435 6.5E-130 T 14-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily D521_1884 ee24d376d1b0fb61c1f0c3b81ff3da69 440 Pfam PF05161 MOFRL family 326 432 3.7E-32 T 14-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 D521_1855 09006bc03ae5c706fc18421393793c82 279 SMART SM01091 197 275 3.9E-24 T 14-10-2018 IPR005170 Transporter-associated domain D521_1855 09006bc03ae5c706fc18421393793c82 279 SUPERFAMILY SSF56176 196 277 5.18E-20 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 D521_1855 09006bc03ae5c706fc18421393793c82 279 Pfam PF03471 Transporter associated domain 199 270 3.6E-18 T 14-10-2018 IPR005170 Transporter-associated domain D521_1855 09006bc03ae5c706fc18421393793c82 279 Gene3D G3DSA:3.30.465.10 189 274 1.2E-24 T 14-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 D521_1855 09006bc03ae5c706fc18421393793c82 279 Gene3D G3DSA:3.10.580.10 42 188 1.7E-49 T 14-10-2018 D521_1855 09006bc03ae5c706fc18421393793c82 279 SUPERFAMILY SSF54631 59 192 3.79E-29 T 14-10-2018 D521_1855 09006bc03ae5c706fc18421393793c82 279 SMART SM00116 71 120 20.0 T 14-10-2018 IPR000644 CBS domain D521_1855 09006bc03ae5c706fc18421393793c82 279 SMART SM00116 132 180 0.7 T 14-10-2018 IPR000644 CBS domain D521_1855 09006bc03ae5c706fc18421393793c82 279 Pfam PF00571 CBS domain 57 118 3.1E-4 T 14-10-2018 IPR000644 CBS domain D521_1855 09006bc03ae5c706fc18421393793c82 279 Pfam PF00571 CBS domain 131 180 7.9E-5 T 14-10-2018 IPR000644 CBS domain D521_1334 eb5e04dc20f9261acc113422540ab660 328 Gene3D G3DSA:3.40.190.10 132 253 3.2E-106 T 14-10-2018 D521_1334 eb5e04dc20f9261acc113422540ab660 328 PIRSF PIRSF017082 2 328 7.2E-74 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1334 eb5e04dc20f9261acc113422540ab660 328 SUPERFAMILY SSF53850 118 291 4.03E-12 T 14-10-2018 D521_1334 eb5e04dc20f9261acc113422540ab660 328 Gene3D G3DSA:3.40.190.150 34 318 3.2E-106 T 14-10-2018 D521_1334 eb5e04dc20f9261acc113422540ab660 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 54 324 4.3E-83 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0655 4ffde5cce221c39dcdb3a822d82a34bf 581 SUPERFAMILY SSF46894 29 90 2.24E-18 T 14-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 D521_0655 4ffde5cce221c39dcdb3a822d82a34bf 581 Gene3D G3DSA:1.10.10.10 24 96 1.1E-20 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0655 4ffde5cce221c39dcdb3a822d82a34bf 581 SMART SM00421 31 88 1.6E-20 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0655 4ffde5cce221c39dcdb3a822d82a34bf 581 Pfam PF00196 Bacterial regulatory proteins, luxR family 33 87 1.7E-15 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0655 4ffde5cce221c39dcdb3a822d82a34bf 581 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 64 76 5.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0655 4ffde5cce221c39dcdb3a822d82a34bf 581 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 48 64 5.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0655 4ffde5cce221c39dcdb3a822d82a34bf 581 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 34 48 5.5E-10 T 14-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 D521_0284 ff54434267d4d627a9a23dd5af182377 127 PIRSF PIRSF018634 4 127 5.2E-36 T 14-10-2018 IPR009387 Toxin HigB-2 D521_0284 ff54434267d4d627a9a23dd5af182377 127 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 5 122 6.4E-39 T 14-10-2018 IPR009387 Toxin HigB-2 D521_0633 f62d1059499540eeae3b8403a2042e84 373 Gene3D G3DSA:1.20.120.1460 286 352 5.1E-9 T 14-10-2018 D521_0633 f62d1059499540eeae3b8403a2042e84 373 Gene3D G3DSA:3.20.20.70 18 266 9.1E-66 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0633 f62d1059499540eeae3b8403a2042e84 373 SUPERFAMILY SSF51395 21 344 9.77E-59 T 14-10-2018 D521_0633 f62d1059499540eeae3b8403a2042e84 373 Pfam PF01207 Dihydrouridine synthase (Dus) 24 348 1.3E-67 T 14-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 D521_0633 f62d1059499540eeae3b8403a2042e84 373 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 103 121 - T 14-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 D521_0760 17626f1a16829e7d6ff8d69f247ed3d3 200 ProSitePatterns PS00893 Nudix box signature. 89 110 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 D521_0760 17626f1a16829e7d6ff8d69f247ed3d3 200 SUPERFAMILY SSF55811 21 187 5.82E-45 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 D521_0760 17626f1a16829e7d6ff8d69f247ed3d3 200 Gene3D G3DSA:3.90.79.10 14 193 1.7E-50 T 14-10-2018 D521_0760 17626f1a16829e7d6ff8d69f247ed3d3 200 Pfam PF00293 NUDIX domain 55 167 1.8E-15 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 156 6.9E-55 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 57 9.8E-17 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 SUPERFAMILY SSF52374 3 156 3.66E-44 T 14-10-2018 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 Pfam PF01467 Cytidylyltransferase-like 5 133 5.9E-18 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 1.5E-44 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 112 134 1.5E-44 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 1.5E-44 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 1.5E-44 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 1.5E-44 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 158 34.869 T 14-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 D521_1921 0106de9f3ba09ea37173e1a9ec1e4c94 164 Gene3D G3DSA:3.40.50.620 1 164 2.0E-55 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0769 974028864ee360f3b25917dcd396e46d 361 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 11 357 3.6E-83 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 D521_0769 974028864ee360f3b25917dcd396e46d 361 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 249 268 - T 14-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 D521_0769 974028864ee360f3b25917dcd396e46d 361 Gene3D G3DSA:3.40.718.10 6 361 3.5E-134 T 14-10-2018 D521_0769 974028864ee360f3b25917dcd396e46d 361 SMART SM01329 11 357 2.5E-171 T 14-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 D521_0769 974028864ee360f3b25917dcd396e46d 361 TIGRFAM TIGR02089 TTC: tartrate dehydrogenase 9 360 8.5E-169 T 14-10-2018 IPR011829 Tartrate dehydrogenase GO:0016616|GO:0051287|GO:0055114 KEGG: 00630+1.1.1.93|KEGG: 00650+1.1.1.83 D521_0769 974028864ee360f3b25917dcd396e46d 361 SUPERFAMILY SSF53659 4 360 9.6E-114 T 14-10-2018 D521_0696 5a8e2655f0fe8cd902b578fa44f3ff5a 75 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 3 71 2.4E-22 T 14-10-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system D521_1061 53fea500d277a7368a663b8af6592d37 409 SUPERFAMILY SSF103473 7 402 3.01E-62 T 14-10-2018 IPR036259 MFS transporter superfamily D521_1061 53fea500d277a7368a663b8af6592d37 409 Pfam PF07690 Major Facilitator Superfamily 22 246 2.3E-31 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_1061 53fea500d277a7368a663b8af6592d37 409 Gene3D G3DSA:1.20.1250.20 10 401 7.1E-58 T 14-10-2018 D521_0489 9fd372f4842aa1480a2950242a88ce5e 313 SUPERFAMILY SSF53850 90 299 1.01E-37 T 14-10-2018 D521_0489 9fd372f4842aa1480a2950242a88ce5e 313 Gene3D G3DSA:3.40.190.10 167 267 1.0E-89 T 14-10-2018 D521_0489 9fd372f4842aa1480a2950242a88ce5e 313 Gene3D G3DSA:1.10.10.10 1 86 1.7E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0489 9fd372f4842aa1480a2950242a88ce5e 313 SUPERFAMILY SSF46785 2 87 1.8E-13 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0489 9fd372f4842aa1480a2950242a88ce5e 313 Pfam PF03466 LysR substrate binding domain 90 291 8.9E-37 T 14-10-2018 IPR005119 LysR, substrate-binding D521_0489 9fd372f4842aa1480a2950242a88ce5e 313 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 1.5E-13 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_0489 9fd372f4842aa1480a2950242a88ce5e 313 Gene3D G3DSA:3.40.190.10 91 303 1.0E-89 T 14-10-2018 D521_0489 9fd372f4842aa1480a2950242a88ce5e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 6.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_0489 9fd372f4842aa1480a2950242a88ce5e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 6.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_0489 9fd372f4842aa1480a2950242a88ce5e 313 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 6.2E-8 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_0028 1a3b46d969a5d4f7d944f339ad9307cb 380 Pfam PF00487 Fatty acid desaturase 74 328 3.9E-32 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 D521_1499 b243a37eef0cab4ebdffb78e9876e2bd 324 Gene3D G3DSA:3.40.50.720 110 307 1.3E-93 T 14-10-2018 D521_1499 b243a37eef0cab4ebdffb78e9876e2bd 324 SUPERFAMILY SSF52283 27 130 2.98E-17 T 14-10-2018 D521_1499 b243a37eef0cab4ebdffb78e9876e2bd 324 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 22 116 1.1E-7 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 D521_1499 b243a37eef0cab4ebdffb78e9876e2bd 324 Gene3D G3DSA:3.40.50.720 7 314 1.3E-93 T 14-10-2018 D521_1499 b243a37eef0cab4ebdffb78e9876e2bd 324 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 153 180 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 D521_1499 b243a37eef0cab4ebdffb78e9876e2bd 324 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 117 291 9.6E-50 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 D521_1499 b243a37eef0cab4ebdffb78e9876e2bd 324 SUPERFAMILY SSF51735 109 291 1.84E-46 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0314 c7ca80623734e9010bf1e9ed88b7e3c5 257 TIGRFAM TIGR02623 G1P_cyt_trans: glucose-1-phosphate cytidylyltransferase 1 256 4.2E-143 T 14-10-2018 IPR013446 Glucose-1-phosphate cytidylyltransferase GO:0047343 KEGG: 00500+2.7.7.33|KEGG: 00520+2.7.7.33|MetaCyc: PWY-5833|MetaCyc: PWY-5940 D521_0314 c7ca80623734e9010bf1e9ed88b7e3c5 257 Gene3D G3DSA:3.90.550.10 1 257 3.3E-74 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0314 c7ca80623734e9010bf1e9ed88b7e3c5 257 Pfam PF00483 Nucleotidyl transferase 2 205 5.6E-21 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 D521_0314 c7ca80623734e9010bf1e9ed88b7e3c5 257 SUPERFAMILY SSF53448 1 256 2.25E-69 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1712 505c01875ea466b6f05c661259837d98 590 Gene3D G3DSA:2.40.240.10 379 504 1.9E-72 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_1712 505c01875ea466b6f05c661259837d98 590 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 49 358 1.4E-104 T 14-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 D521_1712 505c01875ea466b6f05c661259837d98 590 Gene3D G3DSA:3.90.800.10 127 235 3.4E-100 T 14-10-2018 D521_1712 505c01875ea466b6f05c661259837d98 590 SUPERFAMILY SSF52374 49 376 8.58E-93 T 14-10-2018 D521_1712 505c01875ea466b6f05c661259837d98 590 Gene3D G3DSA:1.10.1160.10 292 370 1.2E-33 T 14-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 D521_1712 505c01875ea466b6f05c661259837d98 590 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 7 589 52.628 T 14-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 D521_1712 505c01875ea466b6f05c661259837d98 590 Gene3D G3DSA:2.40.240.10 371 586 1.9E-72 T 14-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_1712 505c01875ea466b6f05c661259837d98 590 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 50 589 6.6E-214 T 14-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 D521_1712 505c01875ea466b6f05c661259837d98 590 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 371 568 3.1E-49 T 14-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_1712 505c01875ea466b6f05c661259837d98 590 Gene3D G3DSA:3.40.50.620 49 273 3.4E-100 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1712 505c01875ea466b6f05c661259837d98 590 SUPERFAMILY SSF50715 371 588 2.46E-67 T 14-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 D521_1712 505c01875ea466b6f05c661259837d98 590 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 55 66 - T 14-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 D521_1980 a938be6f335ad59baf1eb408a840efeb 341 SMART SM00849 27 254 4.2E-23 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_1980 a938be6f335ad59baf1eb408a840efeb 341 Pfam PF00753 Metallo-beta-lactamase superfamily 27 254 1.3E-26 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_1980 a938be6f335ad59baf1eb408a840efeb 341 SUPERFAMILY SSF56281 3 337 1.83E-67 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_1980 a938be6f335ad59baf1eb408a840efeb 341 Gene3D G3DSA:3.60.15.10 8 281 3.7E-54 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_1980 a938be6f335ad59baf1eb408a840efeb 341 Gene3D G3DSA:1.10.10.10 283 332 5.2E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0753 9b6d4de21ffbe144309b9b7db3712da7 357 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 67 82 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0753 9b6d4de21ffbe144309b9b7db3712da7 357 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 21 352 24.726 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0753 9b6d4de21ffbe144309b9b7db3712da7 357 Pfam PF00146 NADH dehydrogenase 28 345 6.4E-127 T 14-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0753 9b6d4de21ffbe144309b9b7db3712da7 357 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 233 246 - T 14-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0820 bf413f7c6d8327bd1864dc7478afeb5f 257 Gene3D G3DSA:3.40.50.300 2 251 2.2E-91 T 14-10-2018 D521_0820 bf413f7c6d8327bd1864dc7478afeb5f 257 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 6 232 2.3E-97 T 14-10-2018 IPR022488 Polyphosphate kinase-2-related D521_0820 bf413f7c6d8327bd1864dc7478afeb5f 257 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 7 233 1.5E-104 T 14-10-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 KEGG: 00190+2.7.4.1 D521_0820 bf413f7c6d8327bd1864dc7478afeb5f 257 PIRSF PIRSF028756 2 252 9.6E-106 T 14-10-2018 IPR016898 Polyphosphate kinase 2 KEGG: 00190+2.7.4.1 D521_0820 bf413f7c6d8327bd1864dc7478afeb5f 257 SUPERFAMILY SSF52540 37 226 1.59E-27 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0215 cb4240a886681e3b76fa73fe64ce469b 175 SUPERFAMILY SSF52833 11 174 5.25E-34 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0215 cb4240a886681e3b76fa73fe64ce469b 175 Pfam PF08534 Redoxin 49 164 2.9E-24 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 D521_0215 cb4240a886681e3b76fa73fe64ce469b 175 Gene3D G3DSA:3.40.30.10 42 174 1.8E-39 T 14-10-2018 D521_0215 cb4240a886681e3b76fa73fe64ce469b 175 ProSitePatterns PS00194 Thioredoxin family active site. 65 83 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 D521_1747 5638ec92a8842c3cd446ebae851f1843 466 SUPERFAMILY SSF81891 189 422 5.89E-44 T 14-10-2018 D521_1747 5638ec92a8842c3cd446ebae851f1843 466 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 30 457 3.1E-147 T 14-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 D521_1747 5638ec92a8842c3cd446ebae851f1843 466 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 217 278 3.1E-17 T 14-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 D521_1747 5638ec92a8842c3cd446ebae851f1843 466 Gene3D G3DSA:1.10.3090.10 188 437 4.3E-80 T 14-10-2018 D521_1747 5638ec92a8842c3cd446ebae851f1843 466 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 24 457 35.07 T 14-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 D521_1747 5638ec92a8842c3cd446ebae851f1843 466 Pfam PF12626 Polymerase A arginine-rich C-terminus 335 454 1.5E-39 T 14-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain D521_1747 5638ec92a8842c3cd446ebae851f1843 466 Gene3D G3DSA:3.30.460.10 28 186 2.8E-55 T 14-10-2018 D521_1747 5638ec92a8842c3cd446ebae851f1843 466 SUPERFAMILY SSF81301 35 187 8.83E-37 T 14-10-2018 D521_1747 5638ec92a8842c3cd446ebae851f1843 466 Pfam PF01743 Poly A polymerase head domain 60 190 1.5E-32 T 14-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 D521_1204 7c5be49d34b542640b63bf54490eec2c 265 SMART SM00014 81 196 0.0016 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase D521_1204 7c5be49d34b542640b63bf54490eec2c 265 SUPERFAMILY SSF48317 12 201 8.24E-25 T 14-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily D521_1204 7c5be49d34b542640b63bf54490eec2c 265 Pfam PF01569 PAP2 superfamily 86 191 1.8E-16 T 14-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase D521_1204 7c5be49d34b542640b63bf54490eec2c 265 Gene3D G3DSA:1.20.144.10 122 213 7.2E-15 T 14-10-2018 D521_2015 12e9da8e076945aaaf490bb53d2eb821 300 Gene3D G3DSA:3.40.1160.10 12 300 2.1E-95 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily D521_2015 12e9da8e076945aaaf490bb53d2eb821 300 Pfam PF00696 Amino acid kinase family 33 276 4.0E-42 T 14-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 D521_2015 12e9da8e076945aaaf490bb53d2eb821 300 Hamap MF_00082 Acetylglutamate kinase [argB]. 32 292 48.578 T 14-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 D521_2015 12e9da8e076945aaaf490bb53d2eb821 300 TIGRFAM TIGR00761 argB: acetylglutamate kinase 34 274 9.0E-74 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 D521_2015 12e9da8e076945aaaf490bb53d2eb821 300 PRINTS PR00474 Glutamate 5-kinase family signature 64 78 5.8E-7 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 D521_2015 12e9da8e076945aaaf490bb53d2eb821 300 PRINTS PR00474 Glutamate 5-kinase family signature 199 226 5.8E-7 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 D521_2015 12e9da8e076945aaaf490bb53d2eb821 300 PRINTS PR00474 Glutamate 5-kinase family signature 249 269 5.8E-7 T 14-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 D521_2015 12e9da8e076945aaaf490bb53d2eb821 300 SUPERFAMILY SSF53633 16 299 2.62E-87 T 14-10-2018 IPR036393 Acetylglutamate kinase-like superfamily D521_2015 12e9da8e076945aaaf490bb53d2eb821 300 PIRSF PIRSF000728 18 299 2.3E-102 T 14-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 D521_1004 eeddf6bdb34dd97e4ede865390f101dd 215 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 3.7E-83 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 D521_1004 eeddf6bdb34dd97e4ede865390f101dd 215 Pfam PF00694 Aconitase C-terminal domain 1 131 1.1E-38 T 14-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 D521_1004 eeddf6bdb34dd97e4ede865390f101dd 215 Gene3D G3DSA:3.20.19.10 1 184 1.2E-77 T 14-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 D521_1004 eeddf6bdb34dd97e4ede865390f101dd 215 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 44.004 T 14-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 D521_1004 eeddf6bdb34dd97e4ede865390f101dd 215 SUPERFAMILY SSF52016 1 201 6.87E-63 T 14-10-2018 D521_1210 2f7db6d7b21e9fa84e639a81730c7ad7 217 Pfam PF13394 4Fe-4S single cluster domain 24 125 7.7E-6 T 14-10-2018 D521_1210 2f7db6d7b21e9fa84e639a81730c7ad7 217 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 2 217 32.103 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 D521_1210 2f7db6d7b21e9fa84e639a81730c7ad7 217 PIRSF PIRSF000370 1 217 1.9E-37 T 14-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 D521_1210 2f7db6d7b21e9fa84e639a81730c7ad7 217 Gene3D G3DSA:3.20.20.70 1 217 2.3E-67 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1210 2f7db6d7b21e9fa84e639a81730c7ad7 217 SUPERFAMILY SSF102114 45 140 9.22E-8 T 14-10-2018 D521_1210 2f7db6d7b21e9fa84e639a81730c7ad7 217 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 2 217 6.0E-98 T 14-10-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 D521_0865 5ca0e89079df784a629e4e0bce8a556b 218 Gene3D G3DSA:1.10.1670.40 23 209 6.2E-63 T 14-10-2018 D521_0865 5ca0e89079df784a629e4e0bce8a556b 218 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 56 192 4.1E-11 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 D521_0865 5ca0e89079df784a629e4e0bce8a556b 218 Gene3D G3DSA:1.10.340.30 49 159 6.2E-63 T 14-10-2018 D521_0865 5ca0e89079df784a629e4e0bce8a556b 218 SUPERFAMILY SSF48150 39 210 8.9E-41 T 14-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 D521_0865 5ca0e89079df784a629e4e0bce8a556b 218 SMART SM00478 59 212 5.7E-13 T 14-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 D521_1829 5f822465110e264e9c9a062d0be526e5 178 Gene3D G3DSA:1.10.10.10 131 175 8.4E-12 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1829 5f822465110e264e9c9a062d0be526e5 178 Hamap MF_01114 Regulatory protein RecX [recX]. 6 178 12.857 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 D521_1829 5f822465110e264e9c9a062d0be526e5 178 Pfam PF02631 RecX family 69 174 1.8E-28 T 14-10-2018 IPR003783 Regulatory protein RecX GO:0006282 D521_1829 5f822465110e264e9c9a062d0be526e5 178 Gene3D G3DSA:1.10.10.10 85 126 3.7E-9 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1412 7c5d64969693d12594465c7c8a158a5b 359 PIRSF PIRSF015557 1 359 5.6E-100 T 14-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 D521_1412 7c5d64969693d12594465c7c8a158a5b 359 TIGRFAM TIGR03837 efp_adjacent_2: conserved hypothetical protein, PP_1857 family 3 358 2.2E-115 T 14-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 D521_1412 7c5d64969693d12594465c7c8a158a5b 359 Pfam PF10093 Uncharacterized protein conserved in bacteria (DUF2331) 3 358 1.2E-112 T 14-10-2018 IPR016633 Uncharacterised conserved protein UCP015557 D521_0112 de9e875b6a266dd0258de240428791df 136 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 67 121 2.0E-19 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 D521_0112 de9e875b6a266dd0258de240428791df 136 SUPERFAMILY SSF141734 18 125 5.1E-46 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 D521_0112 de9e875b6a266dd0258de240428791df 136 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 18 122 30.758 T 14-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 D521_0112 de9e875b6a266dd0258de240428791df 136 Gene3D G3DSA:3.10.20.400 16 109 2.5E-37 T 14-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 D521_0112 de9e875b6a266dd0258de240428791df 136 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 44 118 1.4E-34 T 14-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 D521_0134 46f79629022b9fe5b5cb6087165f8eac 359 Pfam PF03462 PCRF domain 13 203 1.5E-68 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 D521_0134 46f79629022b9fe5b5cb6087165f8eac 359 Gene3D G3DSA:3.30.70.1660 111 342 8.1E-96 T 14-10-2018 D521_0134 46f79629022b9fe5b5cb6087165f8eac 359 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 228 244 - T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 D521_0134 46f79629022b9fe5b5cb6087165f8eac 359 Pfam PF00472 RF-1 domain 213 321 3.1E-41 T 14-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 D521_0134 46f79629022b9fe5b5cb6087165f8eac 359 SMART SM00937 63 178 8.4E-63 T 14-10-2018 IPR005139 Peptide chain release factor GO:0006415 D521_0134 46f79629022b9fe5b5cb6087165f8eac 359 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 357 39.615 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 D521_0134 46f79629022b9fe5b5cb6087165f8eac 359 SUPERFAMILY SSF75620 12 353 1.7E-130 T 14-10-2018 D521_0134 46f79629022b9fe5b5cb6087165f8eac 359 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 355 3.1E-156 T 14-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 D521_0134 46f79629022b9fe5b5cb6087165f8eac 359 Gene3D G3DSA:3.30.160.20 210 297 8.1E-96 T 14-10-2018 D521_1467 1cc9a54b2b49330e33cb02e6e9e10a93 303 SUPERFAMILY SSF53686 8 298 3.54E-90 T 14-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme D521_1467 1cc9a54b2b49330e33cb02e6e9e10a93 303 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 290 8.7E-65 T 14-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme D521_1467 1cc9a54b2b49330e33cb02e6e9e10a93 303 Gene3D G3DSA:3.40.50.1100 12 297 5.7E-105 T 14-10-2018 D521_1467 1cc9a54b2b49330e33cb02e6e9e10a93 303 Gene3D G3DSA:3.40.50.1100 44 149 5.7E-105 T 14-10-2018 D521_1467 1cc9a54b2b49330e33cb02e6e9e10a93 303 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 39 57 - T 14-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 D521_1467 1cc9a54b2b49330e33cb02e6e9e10a93 303 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 301 2.0E-116 T 14-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 D521_1467 1cc9a54b2b49330e33cb02e6e9e10a93 303 TIGRFAM TIGR01138 cysM: cysteine synthase B 8 301 4.4E-137 T 14-10-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 D521_2032 533495b4ab0fb59ea77a5a561e2d8a34 221 Gene3D G3DSA:3.40.1050.10 7 221 1.2E-78 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 D521_2032 533495b4ab0fb59ea77a5a561e2d8a34 221 SMART SM00947 35 198 3.1E-66 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 D521_2032 533495b4ab0fb59ea77a5a561e2d8a34 221 Pfam PF00484 Carbonic anhydrase 42 194 2.5E-49 T 14-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 D521_2032 533495b4ab0fb59ea77a5a561e2d8a34 221 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 47 54 - T 14-10-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 D521_2032 533495b4ab0fb59ea77a5a561e2d8a34 221 SUPERFAMILY SSF53056 4 213 2.88E-72 T 14-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 Pfam PF00551 Formyl transferase 86 264 3.0E-33 T 14-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 Gene3D G3DSA:3.30.70.260 1 83 1.6E-24 T 14-10-2018 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 Gene3D G3DSA:3.40.50.170 86 284 3.4E-72 T 14-10-2018 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 SUPERFAMILY SSF55021 2 84 2.91E-15 T 14-10-2018 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 SUPERFAMILY SSF53328 86 283 2.35E-57 T 14-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 3 282 45.632 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 8 34 3.5E-42 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 40 52 3.5E-42 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 87 109 3.5E-42 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 234 256 3.5E-42 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 256 281 3.5E-42 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 109 136 3.5E-42 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 PIRSF PIRSF036480 3 283 2.8E-102 T 14-10-2018 D521_0679 fe2561476d7b5e15f28ae936f72831ff 284 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 8 282 7.6E-97 T 14-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 D521_1458 cf4e17941fd6ba0e6d90416ebb63d9f2 81 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 77 1.6E-23 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1458 cf4e17941fd6ba0e6d90416ebb63d9f2 81 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 21.2 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1458 cf4e17941fd6ba0e6d90416ebb63d9f2 81 Pfam PF00886 Ribosomal protein S16 8 68 5.4E-22 T 14-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1458 cf4e17941fd6ba0e6d90416ebb63d9f2 81 Gene3D G3DSA:3.30.1320.10 1 81 8.3E-29 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1458 cf4e17941fd6ba0e6d90416ebb63d9f2 81 SUPERFAMILY SSF54565 1 76 3.01E-26 T 14-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1998 e1873ed148db613eb1049bff53fd5dc0 395 SUPERFAMILY SSF53335 18 377 1.02E-86 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1998 e1873ed148db613eb1049bff53fd5dc0 395 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 81 310 3.9E-46 T 14-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 D521_1998 e1873ed148db613eb1049bff53fd5dc0 395 Gene3D G3DSA:3.40.50.12710 4 387 1.3E-108 T 14-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 D521_0686 5b42d5cd2246ada9bf02382efb034c1c 230 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 153 228 3.2E-16 T 14-10-2018 IPR006260 TonB/TolA, C-terminal D521_0686 5b42d5cd2246ada9bf02382efb034c1c 230 Gene3D G3DSA:3.30.1150.10 85 229 8.3E-22 T 14-10-2018 D521_0686 5b42d5cd2246ada9bf02382efb034c1c 230 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 152 228 7.7E-19 T 14-10-2018 IPR037682 TonB, C-terminal GO:0055085 D521_0686 5b42d5cd2246ada9bf02382efb034c1c 230 SUPERFAMILY SSF74653 152 226 2.62E-18 T 14-10-2018 D521_0640 5d34fe8803005370e27e4cffd843e199 463 Pfam PF13629 Pilus formation protein N terminal region 55 119 4.8E-21 T 14-10-2018 IPR032789 Pilus formation protein, N-terminal D521_0640 5d34fe8803005370e27e4cffd843e199 463 PRINTS PR00811 Bacterial general secretion pathway protein D signature 407 421 2.2E-12 T 14-10-2018 IPR001775 GspD/PilQ family D521_0640 5d34fe8803005370e27e4cffd843e199 463 PRINTS PR00811 Bacterial general secretion pathway protein D signature 247 271 2.2E-12 T 14-10-2018 IPR001775 GspD/PilQ family D521_0640 5d34fe8803005370e27e4cffd843e199 463 PRINTS PR00811 Bacterial general secretion pathway protein D signature 188 198 2.2E-12 T 14-10-2018 IPR001775 GspD/PilQ family D521_0640 5d34fe8803005370e27e4cffd843e199 463 PRINTS PR00811 Bacterial general secretion pathway protein D signature 384 402 2.2E-12 T 14-10-2018 IPR001775 GspD/PilQ family D521_0640 5d34fe8803005370e27e4cffd843e199 463 Pfam PF00263 Bacterial type II and III secretion system protein 253 420 4.7E-41 T 14-10-2018 IPR004846 Type II/III secretion system GO:0009306 D521_0727 15fd99a22d71647990fbaf28c75acc56 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 256 1.1E-47 T 14-10-2018 D521_0727 15fd99a22d71647990fbaf28c75acc56 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 1.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0727 15fd99a22d71647990fbaf28c75acc56 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 1.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0727 15fd99a22d71647990fbaf28c75acc56 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 1.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0727 15fd99a22d71647990fbaf28c75acc56 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 221 241 1.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0727 15fd99a22d71647990fbaf28c75acc56 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 1.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0727 15fd99a22d71647990fbaf28c75acc56 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 1.7E-29 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0727 15fd99a22d71647990fbaf28c75acc56 261 SUPERFAMILY SSF51735 6 257 8.74E-69 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0727 15fd99a22d71647990fbaf28c75acc56 261 Gene3D G3DSA:3.40.50.720 3 260 1.4E-64 T 14-10-2018 D521_0503 019042d37b547e514315e62302905080 229 Gene3D G3DSA:3.40.50.1980 94 224 3.6E-29 T 14-10-2018 D521_0503 019042d37b547e514315e62302905080 229 Gene3D G3DSA:3.40.50.1980 1 93 4.1E-15 T 14-10-2018 D521_0503 019042d37b547e514315e62302905080 229 Pfam PF01497 Periplasmic binding protein 1 194 2.3E-22 T 14-10-2018 IPR002491 ABC transporter periplasmic binding domain D521_0503 019042d37b547e514315e62302905080 229 SUPERFAMILY SSF53807 1 221 3.3E-37 T 14-10-2018 D521_1011 55e5325786ab26e6384a5d946fa9f8db 121 PIRSF PIRSF000169 8 121 3.1E-38 T 14-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 D521_1011 55e5325786ab26e6384a5d946fa9f8db 121 Gene3D G3DSA:1.20.1300.10 9 121 9.0E-33 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1011 55e5325786ab26e6384a5d946fa9f8db 121 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 6 108 2.6E-15 T 14-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1011 55e5325786ab26e6384a5d946fa9f8db 121 SUPERFAMILY SSF81343 10 121 1.03E-31 T 14-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1011 55e5325786ab26e6384a5d946fa9f8db 121 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 15 119 6.0E-36 T 14-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 D521_1718 7a5398eecff1f9951a1f7e68b7deeefb 110 Gene3D G3DSA:3.10.50.40 1 110 1.0E-25 T 14-10-2018 D521_1718 7a5398eecff1f9951a1f7e68b7deeefb 110 SUPERFAMILY SSF54534 1 109 1.39E-20 T 14-10-2018 D521_1718 7a5398eecff1f9951a1f7e68b7deeefb 110 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 1 38 2.1E-5 T 14-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain D521_0920 580d252a4fe7c80379776a5d671b1252 246 Gene3D G3DSA:3.40.50.720 1 245 8.2E-83 T 14-10-2018 D521_0920 580d252a4fe7c80379776a5d671b1252 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 8.3E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0920 580d252a4fe7c80379776a5d671b1252 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 8.3E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0920 580d252a4fe7c80379776a5d671b1252 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 8.3E-15 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0920 580d252a4fe7c80379776a5d671b1252 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 5.1E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0920 580d252a4fe7c80379776a5d671b1252 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 5.1E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0920 580d252a4fe7c80379776a5d671b1252 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 5.1E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0920 580d252a4fe7c80379776a5d671b1252 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 5.1E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0920 580d252a4fe7c80379776a5d671b1252 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 5.1E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0920 580d252a4fe7c80379776a5d671b1252 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 5.1E-44 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0920 580d252a4fe7c80379776a5d671b1252 246 SUPERFAMILY SSF51735 3 244 2.44E-76 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0920 580d252a4fe7c80379776a5d671b1252 246 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 244 1.3E-120 T 14-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 D521_0920 580d252a4fe7c80379776a5d671b1252 246 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 D521_0920 580d252a4fe7c80379776a5d671b1252 246 Pfam PF00106 short chain dehydrogenase 4 197 6.5E-63 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0920 580d252a4fe7c80379776a5d671b1252 246 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 189 6.7E-4 T 14-10-2018 D521_0971 bf855b801a6f678576bff195ffa29054 341 Gene3D G3DSA:3.40.250.10 3 120 2.3E-35 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_0971 bf855b801a6f678576bff195ffa29054 341 Pfam PF00581 Rhodanese-like domain 6 115 2.4E-7 T 14-10-2018 IPR001763 Rhodanese-like domain D521_0971 bf855b801a6f678576bff195ffa29054 341 SMART SM00450 1 120 1.3E-4 T 14-10-2018 IPR001763 Rhodanese-like domain D521_0971 bf855b801a6f678576bff195ffa29054 341 ProSitePatterns PS00380 Rhodanese signature 1. 16 27 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 D521_0971 bf855b801a6f678576bff195ffa29054 341 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 4 307 2.2E-105 T 14-10-2018 IPR017582 tRNA 2-selenouridine/geranyl-2-thiouridine synthase GO:0016785|GO:0043828|GO:0070329 D521_0971 bf855b801a6f678576bff195ffa29054 341 SUPERFAMILY SSF52821 7 142 1.96E-21 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_0590 46c9e33c85586fa41bc800bca3bf7230 109 Gene3D G3DSA:1.10.760.10 34 108 3.8E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0590 46c9e33c85586fa41bc800bca3bf7230 109 Pfam PF00034 Cytochrome c 39 82 4.8E-5 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0590 46c9e33c85586fa41bc800bca3bf7230 109 SUPERFAMILY SSF46626 39 103 5.82E-14 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1504 ed9cf033f71df7e902510cfb9aab1a77 259 SUPERFAMILY SSF53213 5 257 2.62E-88 T 14-10-2018 D521_1504 ed9cf033f71df7e902510cfb9aab1a77 259 PIRSF PIRSF006157 1 259 2.8E-89 T 14-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 D521_1504 ed9cf033f71df7e902510cfb9aab1a77 259 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 8 210 7.6E-35 T 14-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 D521_1504 ed9cf033f71df7e902510cfb9aab1a77 259 Gene3D G3DSA:3.40.830.10 1 259 4.5E-88 T 14-10-2018 D521_0379 c3515c01d03703baaec307b21ad6d105 244 Gene3D G3DSA:3.30.70.1560 133 214 3.3E-47 T 14-10-2018 D521_0379 c3515c01d03703baaec307b21ad6d105 244 Gene3D G3DSA:3.30.70.580 66 231 3.3E-47 T 14-10-2018 D521_0379 c3515c01d03703baaec307b21ad6d105 244 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 104 118 - T 14-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 D521_0379 c3515c01d03703baaec307b21ad6d105 244 Pfam PF00849 RNA pseudouridylate synthase 66 197 2.3E-16 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0379 c3515c01d03703baaec307b21ad6d105 244 SUPERFAMILY SSF55120 65 232 3.2E-40 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_0379 c3515c01d03703baaec307b21ad6d105 244 SUPERFAMILY SSF55174 7 85 1.47E-8 T 14-10-2018 D521_0379 c3515c01d03703baaec307b21ad6d105 244 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 70 227 3.3E-37 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 D521_0379 c3515c01d03703baaec307b21ad6d105 244 Gene3D G3DSA:3.10.290.10 2 59 3.1E-5 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 D521_0027 5aa51700a9d2eb4678eb80c28f59d1b7 212 SUPERFAMILY SSF56281 5 210 4.98E-56 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_0027 5aa51700a9d2eb4678eb80c28f59d1b7 212 SMART SM00849 14 194 3.8E-37 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0027 5aa51700a9d2eb4678eb80c28f59d1b7 212 Pfam PF00753 Metallo-beta-lactamase superfamily 12 194 7.2E-31 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0027 5aa51700a9d2eb4678eb80c28f59d1b7 212 Gene3D G3DSA:3.60.15.10 3 212 1.2E-75 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_0577 0e241f83dd94b78e90f8bc9a341f0153 223 Gene3D G3DSA:3.40.50.1820 4 218 2.3E-63 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0577 0e241f83dd94b78e90f8bc9a341f0153 223 SUPERFAMILY SSF53474 12 217 5.36E-47 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0577 0e241f83dd94b78e90f8bc9a341f0153 223 Pfam PF02230 Phospholipase/Carboxylesterase 14 218 8.4E-51 T 14-10-2018 IPR003140 Phospholipase/carboxylesterase/thioesterase GO:0016787 D521_2030 5cf5c75faa18660d23763bed0659f7fd 300 SUPERFAMILY SSF51197 80 241 1.37E-20 T 14-10-2018 D521_2030 5cf5c75faa18660d23763bed0659f7fd 300 Gene3D G3DSA:2.60.120.330 45 231 4.6E-44 T 14-10-2018 IPR027443 Isopenicillin N synthase-like D521_2030 5cf5c75faa18660d23763bed0659f7fd 300 Pfam PF05118 Aspartyl/Asparaginyl beta-hydroxylase 70 224 7.1E-48 T 14-10-2018 IPR007803 Aspartyl/asparaginy/proline hydroxylase GO:0018193 D521_0569 88a67ed1e73632ff7353fcdbe2087487 338 SUPERFAMILY SSF51679 6 327 4.32E-82 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 D521_0569 88a67ed1e73632ff7353fcdbe2087487 338 Gene3D G3DSA:3.20.20.30 2 331 1.4E-96 T 14-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 D521_0569 88a67ed1e73632ff7353fcdbe2087487 338 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 8 328 3.0E-129 T 14-10-2018 IPR019949 Luciferase family oxidoreductase, group 1 D521_0569 88a67ed1e73632ff7353fcdbe2087487 338 Pfam PF00296 Luciferase-like monooxygenase 23 297 3.4E-34 T 14-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 D521_1191 e036b157d10d3af34967b59427fbda27 214 SUPERFAMILY SSF89155 20 213 2.09E-41 T 14-10-2018 IPR036411 TorD-like superfamily D521_1191 e036b157d10d3af34967b59427fbda27 214 Gene3D G3DSA:1.10.3480.10 17 213 3.7E-35 T 14-10-2018 D521_1191 e036b157d10d3af34967b59427fbda27 214 Pfam PF02613 Nitrate reductase delta subunit 60 181 3.3E-24 T 14-10-2018 IPR020945 DMSO/Nitrate reductase chaperone D521_1984 63abaf4458156571a28dca748bc89407 162 SMART SM00903 13 157 1.2E-41 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 D521_1984 63abaf4458156571a28dca748bc89407 162 Pfam PF01613 Flavin reductase like domain 14 158 3.2E-32 T 14-10-2018 IPR002563 Flavin reductase like domain GO:0010181 D521_1984 63abaf4458156571a28dca748bc89407 162 SUPERFAMILY SSF50475 6 158 9.81E-39 T 14-10-2018 D521_1984 63abaf4458156571a28dca748bc89407 162 Gene3D G3DSA:2.30.110.10 1 160 1.4E-41 T 14-10-2018 IPR012349 FMN-binding split barrel GO:0048037 D521_1355 c6f7f0ff9938bbc7227f70328a3767f8 432 TIGRFAM TIGR01849 PHB_depoly_PhaZ: polyhydroxyalkanoate depolymerase, intracellular 2 411 1.3E-175 T 14-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase D521_1355 c6f7f0ff9938bbc7227f70328a3767f8 432 PIRSF PIRSF020818 1 423 3.4E-190 T 14-10-2018 IPR010915 Polyhydroxyalkanoate depolymerase D521_1355 c6f7f0ff9938bbc7227f70328a3767f8 432 Pfam PF06850 PHB de-polymerase C-terminus 211 412 2.2E-93 T 14-10-2018 IPR009656 PHB de-polymerase, C-terminal D521_1355 c6f7f0ff9938bbc7227f70328a3767f8 432 SUPERFAMILY SSF53474 106 410 1.21E-30 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0880 d1a9f706872ad1e0aa90b379edade923 433 Pfam PF01136 Peptidase family U32 79 321 8.9E-98 T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 D521_0880 d1a9f706872ad1e0aa90b379edade923 433 Pfam PF16325 Peptidase family U32 C-terminal domain 338 416 2.5E-20 T 14-10-2018 IPR032525 Peptidase family U32, C-terminal D521_0880 d1a9f706872ad1e0aa90b379edade923 433 Gene3D G3DSA:2.40.30.10 335 418 3.7E-11 T 14-10-2018 D521_0880 d1a9f706872ad1e0aa90b379edade923 433 ProSitePatterns PS01276 Peptidase family U32 signature. 164 182 - T 14-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 D521_0464 6e7c99a1de38168af70ef7a2662a443a 340 Pfam PF00589 Phage integrase family 164 323 8.0E-20 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 D521_0464 6e7c99a1de38168af70ef7a2662a443a 340 Gene3D G3DSA:1.10.443.10 159 338 1.7E-38 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 D521_0464 6e7c99a1de38168af70ef7a2662a443a 340 SUPERFAMILY SSF56349 64 331 7.06E-43 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_0271 6c73761dd9aded53450c97896f314d7d 205 Gene3D G3DSA:2.40.30.20 100 205 8.8E-31 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0271 6c73761dd9aded53450c97896f314d7d 205 Gene3D G3DSA:2.40.30.20 1 87 3.5E-21 T 14-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 D521_0271 6c73761dd9aded53450c97896f314d7d 205 SUPERFAMILY SSF63380 1 91 5.78E-19 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel D521_0271 6c73761dd9aded53450c97896f314d7d 205 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 202 1.2E-56 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0271 6c73761dd9aded53450c97896f314d7d 205 SUPERFAMILY SSF63380 91 202 4.76E-28 T 14-10-2018 IPR017938 Riboflavin synthase-like beta-barrel D521_0271 6c73761dd9aded53450c97896f314d7d 205 Pfam PF00677 Lumazine binding domain 3 84 9.3E-13 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0271 6c73761dd9aded53450c97896f314d7d 205 Pfam PF00677 Lumazine binding domain 98 190 2.3E-23 T 14-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0271 6c73761dd9aded53450c97896f314d7d 205 PIRSF PIRSF000498 1 205 3.5E-65 T 14-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0273 1e4973f1d8fb03db1fa4ab8e2c8bcae8 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 12 55 3.1E-7 T 14-10-2018 D521_0273 1e4973f1d8fb03db1fa4ab8e2c8bcae8 84 SUPERFAMILY SSF143120 11 68 1.96E-10 T 14-10-2018 IPR036165 YefM-like superfamily D521_0273 1e4973f1d8fb03db1fa4ab8e2c8bcae8 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 11 74 3.1E-12 T 14-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM D521_1934 46d00e76c0fae7141b84bdc85ec1908e 57 Pfam PF11174 Protein of unknown function (DUF2970) 1 55 2.0E-19 T 14-10-2018 IPR021344 Protein of unknown function DUF2970 D521_2052 7eecf6918b8418b2fc264d78fd211d40 164 SUPERFAMILY SSF109854 2 137 2.01E-26 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes D521_2052 7eecf6918b8418b2fc264d78fd211d40 164 Pfam PF05163 DinB family 2 158 2.5E-23 T 14-10-2018 IPR007837 DNA damage-inducible protein DinB D521_2052 7eecf6918b8418b2fc264d78fd211d40 164 Gene3D G3DSA:1.20.120.450 1 153 6.2E-30 T 14-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes D521_0528 f80b07e35fe2b2f242d4fec78a2eef41 249 Gene3D G3DSA:3.40.50.720 5 249 9.2E-81 T 14-10-2018 D521_0528 f80b07e35fe2b2f242d4fec78a2eef41 249 Pfam PF00899 ThiF family 22 246 5.2E-33 T 14-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 D521_0528 f80b07e35fe2b2f242d4fec78a2eef41 249 SUPERFAMILY SSF69572 12 247 2.09E-53 T 14-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 D521_0326 0d22af209c8f662c0d1dfc6673832a08 310 Pfam PF00535 Glycosyl transferase family 2 6 169 7.9E-23 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 D521_0326 0d22af209c8f662c0d1dfc6673832a08 310 Gene3D G3DSA:3.90.550.10 1 201 4.1E-24 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0326 0d22af209c8f662c0d1dfc6673832a08 310 SUPERFAMILY SSF53448 3 255 3.47E-27 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_2022 1994b26f0d05dcbd8a738d1b925e01da 97 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 97 18.357 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 D521_2022 1994b26f0d05dcbd8a738d1b925e01da 97 Gene3D G3DSA:1.10.20.60 1 95 6.3E-19 T 14-10-2018 D521_2022 1994b26f0d05dcbd8a738d1b925e01da 97 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 17 92 7.1E-16 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 D521_2022 1994b26f0d05dcbd8a738d1b925e01da 97 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 1 97 1.9E-25 T 14-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 D521_2022 1994b26f0d05dcbd8a738d1b925e01da 97 SUPERFAMILY SSF141000 3 95 2.09E-22 T 14-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 D521_0380 415f7fb4ff2e09bf706f6aa5195626ef 100 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 4 95 20.009 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 D521_0380 415f7fb4ff2e09bf706f6aa5195626ef 100 SUPERFAMILY SSF55248 17 95 2.62E-27 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 D521_0380 415f7fb4ff2e09bf706f6aa5195626ef 100 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 17 93 1.9E-25 T 14-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 D521_0380 415f7fb4ff2e09bf706f6aa5195626ef 100 Gene3D G3DSA:3.30.1360.20 7 98 2.2E-29 T 14-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 D521_2036 e91b46ee3e78fa11bd2b7cb0ed98220c 245 Gene3D G3DSA:3.10.290.10 1 58 3.2E-15 T 14-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 D521_2036 e91b46ee3e78fa11bd2b7cb0ed98220c 245 Gene3D G3DSA:3.30.2350.10 62 245 9.1E-45 T 14-10-2018 D521_2036 e91b46ee3e78fa11bd2b7cb0ed98220c 245 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 106 239 7.0E-38 T 14-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 D521_2036 e91b46ee3e78fa11bd2b7cb0ed98220c 245 SMART SM00363 5 62 2.0E-6 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_2036 e91b46ee3e78fa11bd2b7cb0ed98220c 245 SUPERFAMILY SSF55174 5 84 7.2E-12 T 14-10-2018 D521_2036 e91b46ee3e78fa11bd2b7cb0ed98220c 245 SUPERFAMILY SSF55120 65 243 1.3E-37 T 14-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_2036 e91b46ee3e78fa11bd2b7cb0ed98220c 245 Pfam PF00849 RNA pseudouridylate synthase 66 209 3.7E-10 T 14-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 D521_2036 e91b46ee3e78fa11bd2b7cb0ed98220c 245 Pfam PF01479 S4 domain 6 43 1.3E-9 T 14-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_1495 e85fc8552f644bf6423d27b8434fc270 396 SUPERFAMILY SSF53335 183 334 4.29E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1495 e85fc8552f644bf6423d27b8434fc270 396 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 211 288 7.1E-12 T 14-10-2018 D521_1495 e85fc8552f644bf6423d27b8434fc270 396 Gene3D G3DSA:3.40.50.150 206 384 2.4E-24 T 14-10-2018 D521_1495 e85fc8552f644bf6423d27b8434fc270 396 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 285 291 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 D521_1436 2c50c922ffd0b669c1971cccedaefd35 228 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 92 185 6.0E-9 T 14-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 D521_1436 2c50c922ffd0b669c1971cccedaefd35 228 Gene3D G3DSA:3.40.50.1000 14 208 2.9E-51 T 14-10-2018 IPR023214 HAD superfamily D521_1436 2c50c922ffd0b669c1971cccedaefd35 228 SUPERFAMILY SSF56784 9 221 2.44E-53 T 14-10-2018 IPR036412 HAD-like superfamily D521_1436 2c50c922ffd0b669c1971cccedaefd35 228 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 84 192 5.4E-13 T 14-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 D521_1436 2c50c922ffd0b669c1971cccedaefd35 228 Gene3D G3DSA:1.10.150.240 26 91 2.9E-51 T 14-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 D521_1436 2c50c922ffd0b669c1971cccedaefd35 228 Pfam PF13419 Haloacid dehalogenase-like hydrolase 14 191 1.8E-33 T 14-10-2018 D521_0194 46790ac1e6b95a55e6f0d0dddfd45dea 311 Pfam PF07355 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) 30 176 1.8E-7 T 14-10-2018 IPR010187 Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family GO:0050485|GO:0055114 D521_0829 591bfda2ba24f7f73bc27bef47ccc791 385 Pfam PF12832 MFS_1 like family 9 361 9.9E-69 T 14-10-2018 IPR024989 Major facilitator superfamily associated domain D521_0829 591bfda2ba24f7f73bc27bef47ccc791 385 Gene3D G3DSA:1.20.1250.20 4 191 3.3E-22 T 14-10-2018 D521_0829 591bfda2ba24f7f73bc27bef47ccc791 385 Gene3D G3DSA:1.20.1250.20 194 381 5.2E-36 T 14-10-2018 D521_0829 591bfda2ba24f7f73bc27bef47ccc791 385 SUPERFAMILY SSF103473 6 382 1.05E-48 T 14-10-2018 IPR036259 MFS transporter superfamily D521_0829 591bfda2ba24f7f73bc27bef47ccc791 385 PIRSF PIRSF004925 1 384 2.5E-94 T 14-10-2018 IPR026032 Probable 3-phenylpropionic acid transporter D521_0849 15260442b8c64fe0dcd49a361195d66e 367 SUPERFAMILY SSF52540 40 178 3.35E-15 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0849 15260442b8c64fe0dcd49a361195d66e 367 Gene3D G3DSA:3.40.50.300 19 188 9.9E-21 T 14-10-2018 D521_0849 15260442b8c64fe0dcd49a361195d66e 367 Pfam PF03969 AFG1-like ATPase 5 356 3.9E-126 T 14-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 D521_1905 a8077eb192fab905f76976f50214abc6 214 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 18 205 4.4E-35 T 14-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 D521_1905 a8077eb192fab905f76976f50214abc6 214 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 23 206 9.8E-29 T 14-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related D521_0497 652bd1b09231592120d72cb4f2b7d231 507 SUPERFAMILY SSF56801 2 507 4.06E-138 T 14-10-2018 D521_0497 652bd1b09231592120d72cb4f2b7d231 507 Gene3D G3DSA:3.40.50.12780 7 402 9.4E-120 T 14-10-2018 D521_0497 652bd1b09231592120d72cb4f2b7d231 507 Pfam PF00501 AMP-binding enzyme 14 411 5.5E-94 T 14-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 D521_0497 652bd1b09231592120d72cb4f2b7d231 507 Pfam PF13193 AMP-binding enzyme C-terminal domain 420 495 7.8E-16 T 14-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain D521_0497 652bd1b09231592120d72cb4f2b7d231 507 Gene3D G3DSA:3.30.300.310 407 507 4.5E-30 T 14-10-2018 D521_0497 652bd1b09231592120d72cb4f2b7d231 507 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 14-10-2018 IPR020845 AMP-binding, conserved site D521_0154 97b5fff41d52c495bfe3ea963e7b9387 258 Gene3D G3DSA:3.90.226.10 2 200 4.8E-75 T 14-10-2018 D521_0154 97b5fff41d52c495bfe3ea963e7b9387 258 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 257 1.7E-80 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 D521_0154 97b5fff41d52c495bfe3ea963e7b9387 258 SUPERFAMILY SSF52096 1 257 5.57E-89 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_0154 97b5fff41d52c495bfe3ea963e7b9387 258 Gene3D G3DSA:1.10.12.10 202 257 1.5E-27 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal D521_0538 07a3a70758f6e847d8a10bccb8b0ab53 334 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 50 329 6.3E-28 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0538 07a3a70758f6e847d8a10bccb8b0ab53 334 Gene3D G3DSA:3.40.190.150 30 315 6.3E-66 T 14-10-2018 D521_0538 07a3a70758f6e847d8a10bccb8b0ab53 334 PIRSF PIRSF017082 1 334 6.7E-100 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0538 07a3a70758f6e847d8a10bccb8b0ab53 334 Gene3D G3DSA:3.40.190.10 127 259 6.3E-66 T 14-10-2018 D521_0997 92de4366a7dd117afaf554b916acfcfd 265 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 262 35.123 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 D521_0997 92de4366a7dd117afaf554b916acfcfd 265 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 14-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 D521_0997 92de4366a7dd117afaf554b916acfcfd 265 Pfam PF00290 Tryptophan synthase alpha chain 8 260 8.3E-88 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 D521_0997 92de4366a7dd117afaf554b916acfcfd 265 Gene3D G3DSA:3.20.20.70 1 265 2.6E-101 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0997 92de4366a7dd117afaf554b916acfcfd 265 SUPERFAMILY SSF51366 1 253 1.98E-91 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 D521_0997 92de4366a7dd117afaf554b916acfcfd 265 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 259 4.5E-80 T 14-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 D521_0168 a98f8ba3ca866fd0b37f9b550abbadcf 539 Pfam PF08245 Mur ligase middle domain 153 368 2.6E-32 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 D521_0168 a98f8ba3ca866fd0b37f9b550abbadcf 539 Gene3D G3DSA:3.40.1190.10 139 387 1.4E-55 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0168 a98f8ba3ca866fd0b37f9b550abbadcf 539 Gene3D G3DSA:3.90.190.20 393 533 1.3E-38 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0168 a98f8ba3ca866fd0b37f9b550abbadcf 539 Pfam PF02875 Mur ligase family, glutamate ligase domain 389 447 3.9E-6 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 D521_0168 a98f8ba3ca866fd0b37f9b550abbadcf 539 SUPERFAMILY SSF51984 23 121 5.49E-6 T 14-10-2018 D521_0168 a98f8ba3ca866fd0b37f9b550abbadcf 539 SUPERFAMILY SSF53623 146 385 7.33E-47 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0168 a98f8ba3ca866fd0b37f9b550abbadcf 539 Gene3D G3DSA:3.40.50.720 21 121 2.6E-13 T 14-10-2018 D521_0168 a98f8ba3ca866fd0b37f9b550abbadcf 539 SUPERFAMILY SSF53244 387 530 4.12E-40 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0168 a98f8ba3ca866fd0b37f9b550abbadcf 539 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 23 530 31.942 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 D521_0168 a98f8ba3ca866fd0b37f9b550abbadcf 539 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 24 528 4.4E-107 T 14-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 D521_1321 40e0ea8c5ae740a76345d0ec630166d2 581 Pfam PF01368 DHH family 76 212 9.9E-11 T 14-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 D521_1321 40e0ea8c5ae740a76345d0ec630166d2 581 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 23 576 3.7E-135 T 14-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 D521_1321 40e0ea8c5ae740a76345d0ec630166d2 581 Gene3D G3DSA:3.90.1640.30 48 328 2.0E-81 T 14-10-2018 D521_1321 40e0ea8c5ae740a76345d0ec630166d2 581 Pfam PF02272 DHHA1 domain 324 457 2.2E-18 T 14-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 D521_1321 40e0ea8c5ae740a76345d0ec630166d2 581 Gene3D G3DSA:3.10.310.30 333 464 2.7E-30 T 14-10-2018 D521_1321 40e0ea8c5ae740a76345d0ec630166d2 581 SUPERFAMILY SSF64182 48 469 5.1E-107 T 14-10-2018 IPR038763 DHH phosphoesterase superfamily D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 Gene3D G3DSA:3.40.1390.10 1 87 3.6E-16 T 14-10-2018 D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 Gene3D G3DSA:3.90.190.20 323 474 4.2E-40 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 SUPERFAMILY SSF53244 324 470 4.81E-32 T 14-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 2 471 30.136 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 SUPERFAMILY SSF63418 25 104 9.68E-18 T 14-10-2018 IPR035911 MurE/MurF, N-terminal D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 Pfam PF01225 Mur ligase family, catalytic domain 29 101 2.6E-6 T 14-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 Gene3D G3DSA:3.40.1190.10 88 320 3.8E-64 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 35 470 5.2E-121 T 14-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 Pfam PF02875 Mur ligase family, glutamate ligase domain 324 401 2.3E-15 T 14-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 SUPERFAMILY SSF53623 107 321 2.22E-45 T 14-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 D521_0166 b1d762f84bd193a3324a5e01e3580ad4 478 Pfam PF08245 Mur ligase middle domain 112 303 1.8E-38 T 14-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 D521_1935 ff42cae09ceaec5c745db2ce0d1a84ff 197 SUPERFAMILY SSF110111 63 180 3.01E-41 T 14-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1935 ff42cae09ceaec5c745db2ce0d1a84ff 197 Gene3D G3DSA:2.60.370.10 62 194 2.6E-39 T 14-10-2018 IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1935 ff42cae09ceaec5c745db2ce0d1a84ff 197 PIRSF PIRSF005413 1 196 2.6E-58 T 14-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1935 ff42cae09ceaec5c745db2ce0d1a84ff 197 Pfam PF04442 Cytochrome c oxidase assembly protein CtaG/Cox11 29 178 4.4E-45 T 14-10-2018 IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11 GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0289 53ab107cc3bd6e798a5f35a7ad3ed82d 152 Pfam PF02472 Biopolymer transport protein ExbD/TolR 24 149 1.6E-24 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 D521_1270 fe3db4f2083dff7087f9dbb31cabf685 298 Gene3D G3DSA:3.40.50.150 100 293 1.8E-41 T 14-10-2018 D521_1270 fe3db4f2083dff7087f9dbb31cabf685 298 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 10 293 1.7E-88 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 D521_1270 fe3db4f2083dff7087f9dbb31cabf685 298 PIRSF PIRSF037167 2 298 1.3E-89 T 14-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 D521_1270 fe3db4f2083dff7087f9dbb31cabf685 298 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 13 287 2.0E-56 T 14-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 D521_1270 fe3db4f2083dff7087f9dbb31cabf685 298 Gene3D G3DSA:1.10.8.10 9 99 2.5E-9 T 14-10-2018 D521_1270 fe3db4f2083dff7087f9dbb31cabf685 298 Pfam PF05175 Methyltransferase small domain 128 215 1.3E-15 T 14-10-2018 IPR007848 Methyltransferase small domain GO:0008168 D521_1270 fe3db4f2083dff7087f9dbb31cabf685 298 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 203 209 - T 14-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 D521_1270 fe3db4f2083dff7087f9dbb31cabf685 298 SUPERFAMILY SSF53335 12 280 5.77E-46 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0347 7808cf9a1f14f43ba44cd537d65e46e1 70 SUPERFAMILY SSF46955 18 64 1.24E-7 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily D521_0347 7808cf9a1f14f43ba44cd537d65e46e1 70 Pfam PF12728 Helix-turn-helix domain 19 61 1.6E-8 T 14-10-2018 D521_0347 7808cf9a1f14f43ba44cd537d65e46e1 70 Gene3D G3DSA:1.10.1660.10 12 69 1.3E-6 T 14-10-2018 D521_0512 76ecbf2b5115724bdc40e7822898dc72 289 Pfam PF02616 Segregation and condensation protein ScpA 68 283 1.6E-32 T 14-10-2018 IPR003768 Segregation and condensation protein A D521_0512 76ecbf2b5115724bdc40e7822898dc72 289 Hamap MF_01805 Segregation and condensation protein A [scpA]. 51 285 20.912 T 14-10-2018 IPR003768 Segregation and condensation protein A D521_1106 e7d00582db1d9e55ac5d23b4714f84ba 277 Gene3D G3DSA:1.25.40.10 33 113 1.2E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1106 e7d00582db1d9e55ac5d23b4714f84ba 277 SUPERFAMILY SSF48452 39 97 1.94E-8 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1716 679cce3117cb854d0edf9241650721aa 317 Gene3D G3DSA:3.40.50.11270 22 106 1.6E-110 T 14-10-2018 D521_1716 679cce3117cb854d0edf9241650721aa 317 Gene3D G3DSA:3.40.1010.20 16 287 1.6E-110 T 14-10-2018 D521_1716 679cce3117cb854d0edf9241650721aa 317 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 11 293 36.874 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 D521_1716 679cce3117cb854d0edf9241650721aa 317 Pfam PF02401 LytB protein 13 289 3.4E-91 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 D521_1716 679cce3117cb854d0edf9241650721aa 317 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 12 292 3.0E-100 T 14-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 D521_1716 679cce3117cb854d0edf9241650721aa 317 Gene3D G3DSA:3.40.1010.20 107 203 1.6E-110 T 14-10-2018 D521_1486 e1684b3262a70656a68406dbffdabfc3 229 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 7 229 36.362 T 14-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 D521_1486 e1684b3262a70656a68406dbffdabfc3 229 Pfam PF13489 Methyltransferase domain 45 199 5.0E-25 T 14-10-2018 D521_1486 e1684b3262a70656a68406dbffdabfc3 229 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 7 224 5.3E-85 T 14-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 D521_1486 e1684b3262a70656a68406dbffdabfc3 229 SUPERFAMILY SSF53335 11 228 3.65E-48 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1486 e1684b3262a70656a68406dbffdabfc3 229 Gene3D G3DSA:3.40.50.150 7 229 4.1E-75 T 14-10-2018 D521_1899 f58ca49156c44a50dfa0ef3755dc3208 151 SUPERFAMILY SSF50249 3 151 4.11E-58 T 14-10-2018 IPR012340 Nucleic acid-binding, OB-fold D521_1899 f58ca49156c44a50dfa0ef3755dc3208 151 Pfam PF00436 Single-strand binding protein family 4 108 1.2E-43 T 14-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 D521_1899 f58ca49156c44a50dfa0ef3755dc3208 151 Gene3D G3DSA:2.40.50.140 1 120 6.1E-49 T 14-10-2018 D521_1899 f58ca49156c44a50dfa0ef3755dc3208 151 Hamap MF_00984 Single-stranded DNA-binding protein. 4 112 39.177 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 D521_1899 f58ca49156c44a50dfa0ef3755dc3208 151 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 151 4.2E-53 T 14-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 D521_1899 f58ca49156c44a50dfa0ef3755dc3208 151 PIRSF PIRSF002070 1 150 7.0E-38 T 14-10-2018 D521_1772 8db7b7062236d75bfa094ca881f34c31 108 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 20 100 3.6E-29 T 14-10-2018 IPR003849 Preprotein translocase YajC D521_1772 8db7b7062236d75bfa094ca881f34c31 108 PRINTS PR01853 Bacterial YajC preprotein translocase signature 20 40 2.4E-16 T 14-10-2018 IPR003849 Preprotein translocase YajC D521_1772 8db7b7062236d75bfa094ca881f34c31 108 PRINTS PR01853 Bacterial YajC preprotein translocase signature 58 76 2.4E-16 T 14-10-2018 IPR003849 Preprotein translocase YajC D521_1772 8db7b7062236d75bfa094ca881f34c31 108 Pfam PF02699 Preprotein translocase subunit 21 97 1.7E-30 T 14-10-2018 IPR003849 Preprotein translocase YajC D521_1772 8db7b7062236d75bfa094ca881f34c31 108 SMART SM01323 18 100 2.1E-44 T 14-10-2018 IPR003849 Preprotein translocase YajC D521_0660 f6d65b7b05acc3822d12433e0b504bcd 824 Gene3D G3DSA:2.150.10.10 263 406 1.8E-15 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal D521_0660 f6d65b7b05acc3822d12433e0b504bcd 824 PRINTS PR00313 NodO calcium binding signature 305 313 7.0E-7 T 14-10-2018 D521_0660 f6d65b7b05acc3822d12433e0b504bcd 824 PRINTS PR00313 NodO calcium binding signature 284 295 7.0E-7 T 14-10-2018 D521_0660 f6d65b7b05acc3822d12433e0b504bcd 824 PRINTS PR00313 NodO calcium binding signature 296 304 7.0E-7 T 14-10-2018 D521_0660 f6d65b7b05acc3822d12433e0b504bcd 824 PRINTS PR00313 NodO calcium binding signature 314 323 7.0E-7 T 14-10-2018 D521_0660 f6d65b7b05acc3822d12433e0b504bcd 824 ProSitePatterns PS00330 Hemolysin-type calcium-binding region signature. 292 310 - T 14-10-2018 IPR018511 Hemolysin-type calcium-binding conserved site D521_0660 f6d65b7b05acc3822d12433e0b504bcd 824 Pfam PF16184 Cadherin-like 55 153 1.7E-16 T 14-10-2018 D521_0660 f6d65b7b05acc3822d12433e0b504bcd 824 ProSitePatterns PS00018 EF-hand calcium-binding domain. 565 577 - T 14-10-2018 IPR018247 EF-Hand 1, calcium-binding site D521_0660 f6d65b7b05acc3822d12433e0b504bcd 824 SUPERFAMILY SSF51120 257 376 1.44E-6 T 14-10-2018 IPR011049 Serralysin-like metalloprotease, C-terminal D521_0482 5b4968b38531967738c483d02b7695fb 181 Pfam PF02545 Maf-like protein 19 174 3.9E-39 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 D521_0482 5b4968b38531967738c483d02b7695fb 181 PIRSF PIRSF006305 6 181 1.0E-33 T 14-10-2018 IPR003697 Maf-like protein GO:0047429 D521_0482 5b4968b38531967738c483d02b7695fb 181 Gene3D G3DSA:3.90.950.10 1 179 7.6E-51 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like D521_0482 5b4968b38531967738c483d02b7695fb 181 SUPERFAMILY SSF52972 12 173 5.95E-40 T 14-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like D521_0263 6fc250a5c2f5f95df8c4a39b6d7a80c5 171 Gene3D G3DSA:3.40.50.960 10 158 1.3E-50 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0263 6fc250a5c2f5f95df8c4a39b6d7a80c5 171 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 17 158 26.483 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0263 6fc250a5c2f5f95df8c4a39b6d7a80c5 171 SUPERFAMILY SSF52121 15 156 1.7E-49 T 14-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0263 6fc250a5c2f5f95df8c4a39b6d7a80c5 171 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 22 154 2.0E-47 T 14-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0263 6fc250a5c2f5f95df8c4a39b6d7a80c5 171 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 22 154 3.1E-39 T 14-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 D521_0822 c59cfe3427a8f1a3a2bb4d5eef4a793d 394 Pfam PF07690 Major Facilitator Superfamily 16 212 8.7E-17 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_0822 c59cfe3427a8f1a3a2bb4d5eef4a793d 394 Pfam PF07690 Major Facilitator Superfamily 231 386 1.9E-13 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_0822 c59cfe3427a8f1a3a2bb4d5eef4a793d 394 Gene3D G3DSA:1.20.1250.20 209 394 2.2E-21 T 14-10-2018 D521_0822 c59cfe3427a8f1a3a2bb4d5eef4a793d 394 Gene3D G3DSA:1.20.1250.20 9 195 2.6E-23 T 14-10-2018 D521_0822 c59cfe3427a8f1a3a2bb4d5eef4a793d 394 SUPERFAMILY SSF103473 10 386 1.96E-52 T 14-10-2018 IPR036259 MFS transporter superfamily D521_1834 45d7c718067ad51eb61655e5ee22fd0a 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 253 3.2E-41 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF D521_1834 45d7c718067ad51eb61655e5ee22fd0a 263 SUPERFAMILY SSF53850 6 253 1.37E-49 T 14-10-2018 D521_1834 45d7c718067ad51eb61655e5ee22fd0a 263 Gene3D G3DSA:3.40.190.10 122 212 4.0E-56 T 14-10-2018 D521_1834 45d7c718067ad51eb61655e5ee22fd0a 263 SMART SM00062 34 254 1.2E-39 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF D521_1834 45d7c718067ad51eb61655e5ee22fd0a 263 Gene3D G3DSA:3.40.190.10 26 245 4.0E-56 T 14-10-2018 D521_1577 dcb0c1b6e019904f0a795de57e943f26 369 SUPERFAMILY SSF56235 24 348 4.78E-78 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_1577 dcb0c1b6e019904f0a795de57e943f26 369 Gene3D G3DSA:3.60.60.10 24 362 7.1E-99 T 14-10-2018 D521_1577 dcb0c1b6e019904f0a795de57e943f26 369 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 24 339 7.1E-58 T 14-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal D521_0252 5c263856e951e2216c05e10f011a72af 352 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 336 1.2E-151 T 14-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 D521_0252 5c263856e951e2216c05e10f011a72af 352 SUPERFAMILY SSF51735 2 349 3.11E-87 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0252 5c263856e951e2216c05e10f011a72af 352 Gene3D G3DSA:3.90.25.10 201 331 7.6E-130 T 14-10-2018 D521_0252 5c263856e951e2216c05e10f011a72af 352 Gene3D G3DSA:3.40.50.720 2 323 7.6E-130 T 14-10-2018 D521_0252 5c263856e951e2216c05e10f011a72af 352 Pfam PF16363 GDP-mannose 4,6 dehydratase 3 324 2.1E-98 T 14-10-2018 IPR016040 NAD(P)-binding domain D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 Gene3D G3DSA:3.40.50.970 5 326 1.4E-131 T 14-10-2018 D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 TIGRFAM TIGR00232 tktlase_bact: transketolase 8 661 5.6E-294 T 14-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 SUPERFAMILY SSF52518 6 331 5.12E-120 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 Pfam PF02780 Transketolase, C-terminal domain 548 653 1.0E-14 T 14-10-2018 IPR033248 Transketolase, C-terminal domain D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 1.1E-46 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 SUPERFAMILY SSF52518 337 525 1.42E-67 T 14-10-2018 IPR029061 Thiamin diphosphate-binding fold D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 SMART SM00861 355 526 1.5E-69 T 14-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 Gene3D G3DSA:3.40.50.970 327 537 8.4E-85 T 14-10-2018 D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 ProSitePatterns PS00801 Transketolase signature 1. 13 33 - T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 7 333 2.2E-161 T 14-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 SUPERFAMILY SSF52922 533 662 2.22E-41 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 D521_0230 f5f9135b1c67d48d7a89b5c8845e5030 664 Gene3D G3DSA:3.40.50.920 539 664 7.4E-40 T 14-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 D521_0017 d9887cf79b795db2276a8b749dbaa0ac 88 Gene3D G3DSA:1.20.20.10 6 81 1.6E-25 T 14-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0017 d9887cf79b795db2276a8b749dbaa0ac 88 Hamap MF_01396 ATP synthase subunit c [atpH]. 13 78 13.669 T 14-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0017 d9887cf79b795db2276a8b749dbaa0ac 88 SUPERFAMILY SSF81333 7 82 3.79E-18 T 14-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily D521_0017 d9887cf79b795db2276a8b749dbaa0ac 88 ProSitePatterns PS00605 ATP synthase c subunit signature. 43 64 - T 14-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0017 d9887cf79b795db2276a8b749dbaa0ac 88 Pfam PF00137 ATP synthase subunit C 14 76 6.6E-10 T 14-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 D521_0017 d9887cf79b795db2276a8b749dbaa0ac 88 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 24 80 2.1E-20 T 14-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 D521_0566 cd5d0b9e77c7d6c2ed39b42945879407 115 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 7 108 2.2E-28 T 14-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV D521_1733 a75fa290e4fc6b68f2fb7ec3115a57ed 151 Pfam PF02643 Uncharacterized ACR, COG1430 44 146 4.7E-32 T 14-10-2018 IPR003795 Protein of unknown function DUF192 D521_1733 a75fa290e4fc6b68f2fb7ec3115a57ed 151 Gene3D G3DSA:2.60.120.1140 15 146 2.5E-37 T 14-10-2018 IPR038695 Saro_0823-like superfamily D521_1555 38d0e79e3406c9266f38fb5f9b83c12e 194 Gene3D G3DSA:3.40.50.1240 19 187 6.6E-23 T 14-10-2018 IPR029033 Histidine phosphatase superfamily D521_1555 38d0e79e3406c9266f38fb5f9b83c12e 194 SUPERFAMILY SSF53254 37 174 3.93E-15 T 14-10-2018 IPR029033 Histidine phosphatase superfamily D521_1555 38d0e79e3406c9266f38fb5f9b83c12e 194 PIRSF PIRSF000709 27 145 0.001 T 14-10-2018 D521_1555 38d0e79e3406c9266f38fb5f9b83c12e 194 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 37 107 1.4E-8 T 14-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 D521_0826 f5135a6af1bf7929b6a3f3aa93d95297 282 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 15 269 1.9E-48 T 14-10-2018 IPR017039 Virulence factor BrkB D521_0826 f5135a6af1bf7929b6a3f3aa93d95297 282 PIRSF PIRSF035875 3 275 9.5E-40 T 14-10-2018 IPR017039 Virulence factor BrkB D521_0826 f5135a6af1bf7929b6a3f3aa93d95297 282 Pfam PF03631 Virulence factor BrkB 23 269 2.5E-49 T 14-10-2018 IPR017039 Virulence factor BrkB D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 PRINTS PR01959 SuhB family inositol monophosphatase signature 14 36 2.6E-29 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 PRINTS PR01959 SuhB family inositol monophosphatase signature 194 206 2.6E-29 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 PRINTS PR01959 SuhB family inositol monophosphatase signature 152 178 2.6E-29 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 PRINTS PR01959 SuhB family inositol monophosphatase signature 100 119 2.6E-29 T 14-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 Gene3D G3DSA:3.40.190.80 138 257 2.3E-35 T 14-10-2018 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 207 221 - T 14-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 SUPERFAMILY SSF56655 1 255 1.3E-83 T 14-10-2018 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 57 73 1.6E-58 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 204 228 1.6E-58 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 77 93 1.6E-58 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 35 55 1.6E-58 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 126 149 1.6E-58 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 PRINTS PR00377 Inositol monophosphatase superfamily signature 173 194 1.6E-58 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 Pfam PF00459 Inositol monophosphatase family 1 247 5.3E-67 T 14-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 77 90 - T 14-10-2018 IPR020583 Inositol monophosphatase, metal-binding site D521_0860 1a46605e331e3be1cfdf7df17a3f3fa9 259 Gene3D G3DSA:3.30.540.10 1 136 1.3E-50 T 14-10-2018 D521_0483 b55d6924e2e54ba70db5c9b857e6c510 147 Gene3D G3DSA:3.40.1280.10 1 147 1.6E-48 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal D521_0483 b55d6924e2e54ba70db5c9b857e6c510 147 Pfam PF02590 Predicted SPOUT methyltransferase 1 145 8.9E-48 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 D521_0483 b55d6924e2e54ba70db5c9b857e6c510 147 PIRSF PIRSF004505 1 146 3.8E-43 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 D521_0483 b55d6924e2e54ba70db5c9b857e6c510 147 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 146 28.112 T 14-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 D521_0483 b55d6924e2e54ba70db5c9b857e6c510 147 SUPERFAMILY SSF75217 1 144 8.37E-46 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases D521_1812 9f7488fd32dba150d5581c486214bbe5 433 Gene3D G3DSA:3.40.50.1260 50 427 1.3E-141 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 PRINTS PR00477 Phosphoglycerate kinase family signature 349 374 3.1E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 PRINTS PR00477 Phosphoglycerate kinase family signature 49 65 3.1E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 PRINTS PR00477 Phosphoglycerate kinase family signature 145 160 3.1E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 PRINTS PR00477 Phosphoglycerate kinase family signature 173 195 3.1E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 PRINTS PR00477 Phosphoglycerate kinase family signature 405 422 3.1E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 PRINTS PR00477 Phosphoglycerate kinase family signature 71 93 3.1E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 PRINTS PR00477 Phosphoglycerate kinase family signature 382 393 3.1E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 PRINTS PR00477 Phosphoglycerate kinase family signature 204 226 3.1E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 PRINTS PR00477 Phosphoglycerate kinase family signature 227 246 3.1E-78 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 Gene3D G3DSA:3.40.50.1260 206 419 1.3E-141 T 14-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 PIRSF PIRSF000724 14 433 4.6E-133 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 54 64 - T 14-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 Pfam PF00162 Phosphoglycerate kinase 50 419 4.3E-136 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 43 429 38.248 T 14-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_1812 9f7488fd32dba150d5581c486214bbe5 433 SUPERFAMILY SSF53748 50 429 8.13E-137 T 14-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 D521_0382 1892b1d6e2d2e9a7054c67569327a3f0 180 SUPERFAMILY SSF52499 5 180 9.94E-40 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 D521_0382 1892b1d6e2d2e9a7054c67569327a3f0 180 Pfam PF00857 Isochorismatase family 12 157 1.1E-21 T 14-10-2018 IPR000868 Isochorismatase-like GO:0003824 D521_0382 1892b1d6e2d2e9a7054c67569327a3f0 180 Gene3D G3DSA:3.40.50.850 1 180 1.5E-47 T 14-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 D521_0042 930d1bce7a07d1efd39d568c7763ad23 212 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 160 26.238 T 14-10-2018 IPR022973 Ribosomal protein L10 D521_0042 930d1bce7a07d1efd39d568c7763ad23 212 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 8 142 5.0E-4 T 14-10-2018 D521_0042 930d1bce7a07d1efd39d568c7763ad23 212 SUPERFAMILY SSF160369 4 159 1.06E-47 T 14-10-2018 D521_0042 930d1bce7a07d1efd39d568c7763ad23 212 Gene3D G3DSA:3.30.70.1730 4 133 4.9E-34 T 14-10-2018 D521_0042 930d1bce7a07d1efd39d568c7763ad23 212 Pfam PF00466 Ribosomal protein L10 6 100 1.2E-21 T 14-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 D521_1226 a2c51e814a3f36b1113551f588bbd672 111 SUPERFAMILY SSF54285 3 80 5.75E-10 T 14-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp D521_1226 a2c51e814a3f36b1113551f588bbd672 111 Hamap MF_00460 Protein RnfH [rnfH]. 1 96 15.123 T 14-10-2018 IPR005346 RnfH protein D521_1226 a2c51e814a3f36b1113551f588bbd672 111 Pfam PF03658 RnfH family Ubiquitin 19 88 4.3E-13 T 14-10-2018 IPR005346 RnfH protein D521_1226 a2c51e814a3f36b1113551f588bbd672 111 Gene3D G3DSA:3.10.20.280 3 90 3.6E-13 T 14-10-2018 IPR037021 RnfH superfamily D521_1019 ffc5edfc9ac146c15f8174b3393c74ff 244 Pfam PF00043 Glutathione S-transferase, C-terminal domain 147 209 5.6E-12 T 14-10-2018 IPR004046 Glutathione S-transferase, C-terminal D521_1019 ffc5edfc9ac146c15f8174b3393c74ff 244 SUPERFAMILY SSF52833 9 97 1.4E-18 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1019 ffc5edfc9ac146c15f8174b3393c74ff 244 Gene3D G3DSA:3.40.30.10 11 217 4.1E-86 T 14-10-2018 D521_1019 ffc5edfc9ac146c15f8174b3393c74ff 244 Pfam PF02798 Glutathione S-transferase, N-terminal domain 12 92 2.0E-9 T 14-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 D521_1019 ffc5edfc9ac146c15f8174b3393c74ff 244 Gene3D G3DSA:1.20.1050.10 100 208 4.1E-86 T 14-10-2018 D521_1019 ffc5edfc9ac146c15f8174b3393c74ff 244 SUPERFAMILY SSF47616 90 217 1.77E-37 T 14-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily D521_1206 1fec5290fa304d532e15125698ae8eb6 189 Pfam PF04832 SOUL heme-binding protein 4 67 3.0E-16 T 14-10-2018 IPR006917 SOUL haem-binding protein D521_1206 1fec5290fa304d532e15125698ae8eb6 189 Pfam PF04832 SOUL heme-binding protein 73 185 3.8E-34 T 14-10-2018 IPR006917 SOUL haem-binding protein D521_1206 1fec5290fa304d532e15125698ae8eb6 189 Gene3D G3DSA:3.20.80.10 2 189 3.0E-47 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily D521_1206 1fec5290fa304d532e15125698ae8eb6 189 SUPERFAMILY SSF55136 2 187 7.85E-54 T 14-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily D521_1233 f5e0fc44988b34801c9316264d2da453 800 SUPERFAMILY SSF56059 13 393 1.53E-105 T 14-10-2018 D521_1233 f5e0fc44988b34801c9316264d2da453 800 Gene3D G3DSA:3.30.1490.20 11 202 3.5E-72 T 14-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 D521_1233 f5e0fc44988b34801c9316264d2da453 800 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 487 792 2.2E-57 T 14-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 D521_1233 f5e0fc44988b34801c9316264d2da453 800 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 16 798 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 D521_1233 f5e0fc44988b34801c9316264d2da453 800 PIRSF PIRSF000854 10 800 0.0 T 14-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 D521_1233 f5e0fc44988b34801c9316264d2da453 800 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 702 720 - T 14-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 D521_1233 f5e0fc44988b34801c9316264d2da453 800 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 28 353 3.0E-115 T 14-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 D521_1233 f5e0fc44988b34801c9316264d2da453 800 SUPERFAMILY SSF52009 354 475 7.06E-35 T 14-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 D521_1233 f5e0fc44988b34801c9316264d2da453 800 Gene3D G3DSA:3.50.30.10 365 475 7.4E-40 T 14-10-2018 D521_1233 f5e0fc44988b34801c9316264d2da453 800 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 422 433 - T 14-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 D521_1233 f5e0fc44988b34801c9316264d2da453 800 Gene3D G3DSA:3.30.470.20 203 364 1.9E-56 T 14-10-2018 D521_1233 f5e0fc44988b34801c9316264d2da453 800 SUPERFAMILY SSF51621 473 796 8.38E-91 T 14-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 D521_1233 f5e0fc44988b34801c9316264d2da453 800 Pfam PF00391 PEP-utilising enzyme, mobile domain 392 463 5.7E-26 T 14-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 D521_1233 f5e0fc44988b34801c9316264d2da453 800 Gene3D G3DSA:3.20.20.60 486 799 7.9E-95 T 14-10-2018 D521_0316 61562533c50dde0f06b758b44da2fd23 447 Gene3D G3DSA:3.40.640.10 11 315 1.2E-102 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0316 61562533c50dde0f06b758b44da2fd23 447 PIRSF PIRSF000390 7 446 3.7E-119 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase D521_0316 61562533c50dde0f06b758b44da2fd23 447 SUPERFAMILY SSF53383 48 443 2.58E-104 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0316 61562533c50dde0f06b758b44da2fd23 447 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 54 439 2.2E-109 T 14-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase D521_0316 61562533c50dde0f06b758b44da2fd23 447 Gene3D G3DSA:3.90.1150.10 317 447 2.4E-52 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_0507 5b3dbc4af9761c25c1c95efcb9429199 416 Pfam PF02515 CoA-transferase family III 5 393 2.6E-91 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 D521_0507 5b3dbc4af9761c25c1c95efcb9429199 416 SUPERFAMILY SSF89796 1 416 3.01E-121 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_0507 5b3dbc4af9761c25c1c95efcb9429199 416 Hamap MF_00742 Formyl-CoA:oxalate CoA-transferase [frc]. 1 416 62.844 T 14-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 D521_0507 5b3dbc4af9761c25c1c95efcb9429199 416 Gene3D G3DSA:3.40.50.10540 4 408 7.8E-153 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_0507 5b3dbc4af9761c25c1c95efcb9429199 416 TIGRFAM TIGR03253 oxalate_frc: formyl-CoA transferase 2 416 9.8E-219 T 14-10-2018 IPR017659 Formyl-CoA:oxalate CoA-transferase GO:0033608 MetaCyc: PWY-6695 D521_0507 5b3dbc4af9761c25c1c95efcb9429199 416 Gene3D G3DSA:3.30.1540.10 243 339 7.8E-153 T 14-10-2018 D521_1099 dee8f5e4605a60acb21df8b172580f0c 69 Gene3D G3DSA:1.10.260.40 1 69 8.8E-16 T 14-10-2018 D521_1099 dee8f5e4605a60acb21df8b172580f0c 69 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 1 67 2.8E-16 T 14-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 D521_1099 dee8f5e4605a60acb21df8b172580f0c 69 SUPERFAMILY SSF47413 5 66 1.37E-11 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 D521_0676 940696dd31e6807bcaf25a07271b5795 145 PIRSF PIRSF010312 4 143 3.0E-33 T 14-10-2018 IPR016568 Sulphur oxidation, SoxY D521_0676 940696dd31e6807bcaf25a07271b5795 145 TIGRFAM TIGR04487 SoxY_para_1: SoxY-related AACIE arm protein 7 143 1.7E-57 T 14-10-2018 IPR030997 SoxY-related AACIE arm protein D521_0676 940696dd31e6807bcaf25a07271b5795 145 Gene3D G3DSA:2.60.40.2470 20 142 3.0E-28 T 14-10-2018 IPR038162 Ig-like SoxY domain superfamily D521_0676 940696dd31e6807bcaf25a07271b5795 145 Pfam PF13501 Sulfur oxidation protein SoxY 33 141 7.4E-25 T 14-10-2018 IPR032711 Ig-like SoxY domain D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 Gene3D G3DSA:3.40.50.1980 244 360 3.3E-125 T 14-10-2018 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 Pfam PF00815 Histidinol dehydrogenase 30 438 4.7E-167 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 438 40.551 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 PIRSF PIRSF000099 4 440 9.9E-157 T 14-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 39 437 1.1E-158 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 Gene3D G3DSA:3.40.50.1980 36 242 3.3E-125 T 14-10-2018 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 240 272 - T 14-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 PRINTS PR00083 Histidinol dehydrogenase signature 240 261 2.4E-80 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 PRINTS PR00083 Histidinol dehydrogenase signature 331 356 2.4E-80 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 PRINTS PR00083 Histidinol dehydrogenase signature 39 63 2.4E-80 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 PRINTS PR00083 Histidinol dehydrogenase signature 211 236 2.4E-80 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 PRINTS PR00083 Histidinol dehydrogenase signature 181 207 2.4E-80 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 PRINTS PR00083 Histidinol dehydrogenase signature 147 173 2.4E-80 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 PRINTS PR00083 Histidinol dehydrogenase signature 262 281 2.4E-80 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 PRINTS PR00083 Histidinol dehydrogenase signature 372 390 2.4E-80 T 14-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 D521_0106 48505ef5e0841da789ca61cff73d8eb1 440 SUPERFAMILY SSF53720 33 438 5.1E-82 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 D521_0162 adc6005155a30e12ba5f523ac9e21a52 259 SUPERFAMILY SSF81799 60 160 7.06E-32 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 D521_0162 adc6005155a30e12ba5f523ac9e21a52 259 Gene3D G3DSA:1.10.150.170 58 161 8.2E-85 T 14-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 D521_0162 adc6005155a30e12ba5f523ac9e21a52 259 Gene3D G3DSA:3.40.50.150 2 253 8.2E-85 T 14-10-2018 D521_0162 adc6005155a30e12ba5f523ac9e21a52 259 Pfam PF01795 MraW methylase family 2 254 6.2E-85 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 D521_0162 adc6005155a30e12ba5f523ac9e21a52 259 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 2 253 7.8E-86 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 D521_0162 adc6005155a30e12ba5f523ac9e21a52 259 SUPERFAMILY SSF53335 2 253 6.06E-29 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0162 adc6005155a30e12ba5f523ac9e21a52 259 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 1 254 26.772 T 14-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 D521_1179 d0f96c16f631291ae5d29b8a6c98e1c6 394 Gene3D G3DSA:3.40.50.10540 5 387 2.8E-116 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_1179 d0f96c16f631291ae5d29b8a6c98e1c6 394 Gene3D G3DSA:3.30.1540.10 231 324 2.8E-116 T 14-10-2018 D521_1179 d0f96c16f631291ae5d29b8a6c98e1c6 394 Pfam PF02515 CoA-transferase family III 6 371 1.0E-107 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 D521_1179 d0f96c16f631291ae5d29b8a6c98e1c6 394 SUPERFAMILY SSF89796 4 394 4.45E-122 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_1087 39c752a9e4e667505d1496d36c4deab2 516 Pfam PF02321 Outer membrane efflux protein 112 304 3.2E-20 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_1087 39c752a9e4e667505d1496d36c4deab2 516 Pfam PF02321 Outer membrane efflux protein 327 509 4.2E-22 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_1087 39c752a9e4e667505d1496d36c4deab2 516 SUPERFAMILY SSF56954 24 512 4.45E-64 T 14-10-2018 D521_1087 39c752a9e4e667505d1496d36c4deab2 516 Gene3D G3DSA:1.20.1600.10 91 514 6.0E-58 T 14-10-2018 D521_1266 133303e3dda58e932c5c823e31f12c95 356 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 273 330 6.2E-6 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 D521_1266 133303e3dda58e932c5c823e31f12c95 356 SMART SM00771 217 332 3.7E-4 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 D521_1266 133303e3dda58e932c5c823e31f12c95 356 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 233 332 2.0E-4 T 14-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 D521_1266 133303e3dda58e932c5c823e31f12c95 356 SUPERFAMILY SSF64383 217 339 5.1E-15 T 14-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 D521_1782 1fb5de67a9ad23efa3e10533404d2d6b 148 Gene3D G3DSA:2.60.120.10 34 139 1.3E-12 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_1782 1fb5de67a9ad23efa3e10533404d2d6b 148 SUPERFAMILY SSF51182 46 137 3.9E-14 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily D521_1782 1fb5de67a9ad23efa3e10533404d2d6b 148 Pfam PF07883 Cupin domain 67 135 3.0E-9 T 14-10-2018 IPR013096 Cupin 2, conserved barrel D521_1471 f5084f6e9b17f1c1072eed11bb9f7dcc 1052 SUPERFAMILY SSF48452 82 403 3.49E-6 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1471 f5084f6e9b17f1c1072eed11bb9f7dcc 1052 SUPERFAMILY SSF48452 213 382 1.82E-11 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1471 f5084f6e9b17f1c1072eed11bb9f7dcc 1052 Gene3D G3DSA:1.25.40.10 54 482 3.7E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1471 f5084f6e9b17f1c1072eed11bb9f7dcc 1052 Pfam PF12770 CHAT domain 707 1052 6.9E-48 T 14-10-2018 IPR024983 CHAT domain D521_0345 42049b132913f239f179158fa301fb31 356 Pfam PF01757 Acyltransferase family 10 339 9.2E-21 T 14-10-2018 IPR002656 Acyltransferase 3 GO:0016747 D521_1489 8c75892037683f978df3f898505d279f 328 Gene3D G3DSA:3.40.190.150 30 318 4.0E-110 T 14-10-2018 D521_1489 8c75892037683f978df3f898505d279f 328 PIRSF PIRSF017082 3 328 4.2E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1489 8c75892037683f978df3f898505d279f 328 Gene3D G3DSA:3.40.190.10 129 252 4.0E-110 T 14-10-2018 D521_1489 8c75892037683f978df3f898505d279f 328 SUPERFAMILY SSF53850 115 289 2.06E-14 T 14-10-2018 D521_1489 8c75892037683f978df3f898505d279f 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 323 6.3E-89 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 332 4.2E-141 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 SUPERFAMILY SSF82051 2 158 6.54E-54 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 Pfam PF01926 50S ribosome-binding GTPase 161 285 9.4E-25 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 SUPERFAMILY SSF52540 151 341 1.17E-54 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 14-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 Hamap MF_01454 GTPase Obg [obg]. 2 334 46.85 T 14-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 Pfam PF01018 GTP1/OBG 4 158 2.5E-55 T 14-10-2018 IPR006169 GTP1/OBG domain D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 Gene3D G3DSA:2.70.210.12 1 158 5.6E-55 T 14-10-2018 IPR036726 GTP1/OBG domain superfamily D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 PIRSF PIRSF002401 1 362 7.9E-133 T 14-10-2018 IPR035101 GTP-binding protein, Obg-type D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 Gene3D G3DSA:3.40.50.300 159 337 1.3E-53 T 14-10-2018 D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 4.5E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 4.5E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 4.5E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0198 f864c9cf3e35d1c43eadb509dd49afaf 364 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 4.5E-35 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0985 f245df3321802517af3715eca23d1335 466 Gene3D G3DSA:2.60.40.650 338 466 9.0E-45 T 14-10-2018 D521_0985 f245df3321802517af3715eca23d1335 466 Pfam PF00174 Oxidoreductase molybdopterin binding domain 156 312 8.9E-45 T 14-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 D521_0985 f245df3321802517af3715eca23d1335 466 Gene3D G3DSA:3.90.420.10 77 337 1.8E-80 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 D521_0985 f245df3321802517af3715eca23d1335 466 SUPERFAMILY SSF81296 340 454 9.1E-30 T 14-10-2018 IPR014756 Immunoglobulin E-set D521_0985 f245df3321802517af3715eca23d1335 466 TIGRFAM TIGR04555 sulfite_DH_soxC: sulfite dehydrogenase 50 463 2.4E-183 T 14-10-2018 IPR030835 Sulfite dehydrogenase SoxC D521_0985 f245df3321802517af3715eca23d1335 466 SUPERFAMILY SSF56524 102 343 2.22E-68 T 14-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 D521_0985 f245df3321802517af3715eca23d1335 466 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 340 450 3.7E-16 T 14-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 D521_0985 f245df3321802517af3715eca23d1335 466 PRINTS PR00407 Eukaryotic molybdopterin domain signature 419 431 6.4E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_0985 f245df3321802517af3715eca23d1335 466 PRINTS PR00407 Eukaryotic molybdopterin domain signature 281 294 6.4E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_0985 f245df3321802517af3715eca23d1335 466 PRINTS PR00407 Eukaryotic molybdopterin domain signature 140 156 6.4E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_0985 f245df3321802517af3715eca23d1335 466 PRINTS PR00407 Eukaryotic molybdopterin domain signature 362 376 6.4E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_0985 f245df3321802517af3715eca23d1335 466 PRINTS PR00407 Eukaryotic molybdopterin domain signature 264 280 6.4E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_0985 f245df3321802517af3715eca23d1335 466 PRINTS PR00407 Eukaryotic molybdopterin domain signature 297 310 6.4E-15 T 14-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 D521_1022 6407df70ee03630ec2af4fab9fb853bd 437 SUPERFAMILY SSF52540 12 227 7.59E-44 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1022 6407df70ee03630ec2af4fab9fb853bd 437 Gene3D G3DSA:1.10.3710.10 339 437 2.0E-34 T 14-10-2018 D521_1022 6407df70ee03630ec2af4fab9fb853bd 437 Pfam PF16193 AAA C-terminal domain 183 260 9.3E-22 T 14-10-2018 IPR032423 AAA C-terminal domain D521_1022 6407df70ee03630ec2af4fab9fb853bd 437 Gene3D G3DSA:3.40.50.300 6 162 1.7E-43 T 14-10-2018 D521_1022 6407df70ee03630ec2af4fab9fb853bd 437 SUPERFAMILY SSF48019 245 427 9.07E-74 T 14-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 D521_1022 6407df70ee03630ec2af4fab9fb853bd 437 SMART SM00382 46 163 1.1E-14 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1022 6407df70ee03630ec2af4fab9fb853bd 437 Gene3D G3DSA:1.20.272.10 235 338 2.5E-42 T 14-10-2018 D521_1022 6407df70ee03630ec2af4fab9fb853bd 437 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 50 159 3.5E-15 T 14-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 D521_1022 6407df70ee03630ec2af4fab9fb853bd 437 Pfam PF12002 MgsA AAA+ ATPase C terminal 261 425 2.1E-67 T 14-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal D521_0861 9440c4476873f845b30ae5868ce41cf2 262 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 9 218 2.8E-6 T 14-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 D521_0861 9440c4476873f845b30ae5868ce41cf2 262 Gene3D G3DSA:3.60.21.10 7 233 9.4E-12 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like D521_0861 9440c4476873f845b30ae5868ce41cf2 262 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 262 93.328 T 14-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 D521_0861 9440c4476873f845b30ae5868ce41cf2 262 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 9 233 5.3E-68 T 14-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 D521_0861 9440c4476873f845b30ae5868ce41cf2 262 SUPERFAMILY SSF56300 9 234 7.21E-24 T 14-10-2018 D521_1771 f94ead3e127d23e3ae9bdccd82b62600 342 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 332 44.054 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 D521_1771 f94ead3e127d23e3ae9bdccd82b62600 342 Pfam PF01702 Queuine tRNA-ribosyltransferase 90 329 1.4E-84 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 D521_1771 f94ead3e127d23e3ae9bdccd82b62600 342 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 1 332 3.8E-142 T 14-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 D521_1771 f94ead3e127d23e3ae9bdccd82b62600 342 SUPERFAMILY SSF51713 1 333 3.66E-133 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 D521_1771 f94ead3e127d23e3ae9bdccd82b62600 342 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 1 334 5.7E-135 T 14-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 D521_1771 f94ead3e127d23e3ae9bdccd82b62600 342 Gene3D G3DSA:3.20.20.105 1 336 8.7E-142 T 14-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 D521_1451 64bc9e9aa707063316ccf44e7c1b266c 195 SMART SM00479 18 191 8.2E-18 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III D521_1451 64bc9e9aa707063316ccf44e7c1b266c 195 Pfam PF00929 Exonuclease 20 181 4.7E-31 T 14-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III D521_1451 64bc9e9aa707063316ccf44e7c1b266c 195 SUPERFAMILY SSF53098 16 190 4.93E-44 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1451 64bc9e9aa707063316ccf44e7c1b266c 195 Gene3D G3DSA:3.30.420.10 11 192 7.6E-71 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_1451 64bc9e9aa707063316ccf44e7c1b266c 195 Hamap MF_00045 Oligoribonuclease [orn]. 14 192 40.677 T 14-10-2018 IPR022894 Oligoribonuclease GO:0000175 D521_0146 e0809ba4301708987376b6c80b19568f 267 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 264 2.9E-94 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 D521_0146 e0809ba4301708987376b6c80b19568f 267 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 61 79 - T 14-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 D521_0146 e0809ba4301708987376b6c80b19568f 267 Gene3D G3DSA:3.20.20.70 1 267 4.7E-102 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0146 e0809ba4301708987376b6c80b19568f 267 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 267 35.475 T 14-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 D521_0146 e0809ba4301708987376b6c80b19568f 267 SUPERFAMILY SSF51366 1 266 3.06E-88 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 D521_1783 4a4d53a46dff3923d5a74709f9f403cd 321 PIRSF PIRSF017082 2 320 3.7E-70 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1783 4a4d53a46dff3923d5a74709f9f403cd 321 Gene3D G3DSA:3.40.190.10 124 246 1.1E-92 T 14-10-2018 D521_1783 4a4d53a46dff3923d5a74709f9f403cd 321 Gene3D G3DSA:3.40.190.150 26 311 1.1E-92 T 14-10-2018 D521_1783 4a4d53a46dff3923d5a74709f9f403cd 321 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 46 317 4.6E-72 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1783 4a4d53a46dff3923d5a74709f9f403cd 321 SUPERFAMILY SSF53850 114 280 1.01E-10 T 14-10-2018 D521_2045 de858e7c7f5284f2ef4cd1adec0dde68 185 Pfam PF09361 Phasin protein 5 103 1.3E-10 T 14-10-2018 IPR018968 Phasin D521_0406 657657aef833051e7f1b84b3868eed2f 131 Pfam PF01022 Bacterial regulatory protein, arsR family 27 71 1.9E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0406 657657aef833051e7f1b84b3868eed2f 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 4.9E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0406 657657aef833051e7f1b84b3868eed2f 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 53 68 4.9E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0406 657657aef833051e7f1b84b3868eed2f 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 21 36 4.9E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0406 657657aef833051e7f1b84b3868eed2f 131 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 51 4.9E-14 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0406 657657aef833051e7f1b84b3868eed2f 131 SMART SM00418 19 97 1.8E-24 T 14-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 D521_0406 657657aef833051e7f1b84b3868eed2f 131 SUPERFAMILY SSF46785 10 101 1.32E-23 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0406 657657aef833051e7f1b84b3868eed2f 131 Gene3D G3DSA:1.10.10.10 5 103 3.3E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1202 707742bf2ab3541c99f5af78f6b87887 347 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 26 339 6.8E-62 T 14-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD D521_1200 7a84a20c3ac97e613ac9a808884b92e1 268 Pfam PF11249 Protein of unknown function (DUF3047) 64 261 1.3E-57 T 14-10-2018 IPR021409 Protein of unknown function DUF3047 D521_0639 e321feca8f17ea9f79c2ce6c2e9e67a1 259 TIGRFAM TIGR03177 pilus_cpaB: Flp pilus assembly protein CpaB 9 255 8.8E-68 T 14-10-2018 IPR017592 Pilus assembly, Flp-type CpaB D521_0639 e321feca8f17ea9f79c2ce6c2e9e67a1 259 Pfam PF08666 SAF domain 38 98 6.2E-5 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 D521_0639 e321feca8f17ea9f79c2ce6c2e9e67a1 259 SMART SM00858 37 99 5.7E-6 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 D521_0639 e321feca8f17ea9f79c2ce6c2e9e67a1 259 Pfam PF16976 Flp pilus assembly protein RcpC/CpaB 106 209 8.4E-32 T 14-10-2018 IPR031571 Flp pilus assembly protein RcpC/CpaB domain D521_1928 a6092966b02288e0d39121b8413ef28c 297 Pfam PF01040 UbiA prenyltransferase family 30 278 2.0E-58 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 D521_1928 a6092966b02288e0d39121b8413ef28c 297 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 17 294 5.4E-92 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 D521_1928 a6092966b02288e0d39121b8413ef28c 297 Gene3D G3DSA:1.10.357.140 21 184 4.7E-15 T 14-10-2018 D521_1928 a6092966b02288e0d39121b8413ef28c 297 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 14 295 19.26 T 14-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 D521_0723 7aeb681074436b5d069b0bbb946ce0fb 390 Gene3D G3DSA:3.30.750.24 19 127 2.0E-6 T 14-10-2018 IPR036513 STAS domain superfamily D521_0723 7aeb681074436b5d069b0bbb946ce0fb 390 Pfam PF13466 STAS domain 28 110 7.5E-8 T 14-10-2018 IPR002645 STAS domain D521_0723 7aeb681074436b5d069b0bbb946ce0fb 390 SUPERFAMILY SSF52091 27 113 5.69E-7 T 14-10-2018 IPR036513 STAS domain superfamily D521_0723 7aeb681074436b5d069b0bbb946ce0fb 390 Pfam PF02405 Permease MlaE 175 383 2.1E-63 T 14-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 5.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 5.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 5.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 5.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 5.9E-48 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 Gene3D G3DSA:3.40.50.720 1 244 6.4E-93 T 14-10-2018 D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 SUPERFAMILY SSF51735 6 243 6.5E-90 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 242 2.3E-72 T 14-10-2018 D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.4E-14 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 183 7.4E-6 T 14-10-2018 D521_0217 0d5f28ef5c7ced6de1ac25c272d54554 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 14-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 D521_0658 175bc16fd09eb5546b9fc84c3524dd61 523 Gene3D G3DSA:2.60.40.60 228 328 3.5E-14 T 14-10-2018 D521_0658 175bc16fd09eb5546b9fc84c3524dd61 523 SMART SM00112 253 334 6.1E-9 T 14-10-2018 IPR002126 Cadherin-like GO:0005509|GO:0007156|GO:0016020 D521_0658 175bc16fd09eb5546b9fc84c3524dd61 523 SUPERFAMILY SSF49313 236 332 1.44E-11 T 14-10-2018 IPR015919 Cadherin-like superfamily GO:0005509|GO:0016020 D521_0740 a7a2e72fd1e7ba52c884b025213b3fb2 89 SUPERFAMILY SSF47060 5 89 2.56E-34 T 14-10-2018 IPR009068 S15/NS1, RNA-binding D521_0740 a7a2e72fd1e7ba52c884b025213b3fb2 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0740 a7a2e72fd1e7ba52c884b025213b3fb2 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.546 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0740 a7a2e72fd1e7ba52c884b025213b3fb2 89 SMART SM01387 7 88 1.1E-52 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0740 a7a2e72fd1e7ba52c884b025213b3fb2 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 6.0E-33 T 14-10-2018 D521_0740 a7a2e72fd1e7ba52c884b025213b3fb2 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 6 89 1.6E-38 T 14-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0740 a7a2e72fd1e7ba52c884b025213b3fb2 89 Pfam PF00312 Ribosomal protein S15 9 88 3.9E-37 T 14-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0740 a7a2e72fd1e7ba52c884b025213b3fb2 89 Gene3D G3DSA:1.10.287.10 3 89 4.9E-34 T 14-10-2018 D521_1045 13403554828d7ecbac07851c8498c5ea 287 SUPERFAMILY SSF53218 18 228 6.67E-31 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily D521_1045 13403554828d7ecbac07851c8498c5ea 287 Gene3D G3DSA:3.40.980.10 17 191 1.6E-38 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily D521_1045 13403554828d7ecbac07851c8498c5ea 287 Pfam PF00994 Probable molybdopterin binding domain 22 187 4.0E-26 T 14-10-2018 IPR001453 MoaB/Mog domain D521_1045 13403554828d7ecbac07851c8498c5ea 287 SMART SM00852 21 194 3.3E-27 T 14-10-2018 IPR001453 MoaB/Mog domain D521_0211 1e9a00d9f25ed92fcbbabab4d625f5e1 515 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 308 31.764 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 D521_0211 1e9a00d9f25ed92fcbbabab4d625f5e1 515 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 3 306 1.1E-84 T 14-10-2018 D521_0211 1e9a00d9f25ed92fcbbabab4d625f5e1 515 SUPERFAMILY SSF53335 54 289 1.51E-38 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0211 1e9a00d9f25ed92fcbbabab4d625f5e1 515 Pfam PF11906 Protein of unknown function (DUF3426) 342 509 2.0E-11 T 14-10-2018 IPR021834 Protein of unknown function DUF3426 D521_0211 1e9a00d9f25ed92fcbbabab4d625f5e1 515 Gene3D G3DSA:3.40.50.150 112 308 2.6E-56 T 14-10-2018 D521_0211 1e9a00d9f25ed92fcbbabab4d625f5e1 515 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 302 1.8E-68 T 14-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 D521_1520 d4bafffac59bbdd77134885e9617234f 220 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 1 199 1.2E-39 T 14-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain D521_0472 df1be2b484e8389b061e7adcfa3f57d6 394 Gene3D G3DSA:3.40.640.10 23 273 1.5E-117 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_0472 df1be2b484e8389b061e7adcfa3f57d6 394 PIRSF PIRSF000524 6 394 1.0E-122 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 D521_0472 df1be2b484e8389b061e7adcfa3f57d6 394 SUPERFAMILY SSF53383 10 379 8.45E-98 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_0472 df1be2b484e8389b061e7adcfa3f57d6 394 Pfam PF00266 Aminotransferase class-V 13 326 7.5E-35 T 14-10-2018 IPR000192 Aminotransferase class V domain D521_0472 df1be2b484e8389b061e7adcfa3f57d6 394 Gene3D G3DSA:3.90.1150.10 18 383 1.5E-117 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_0325 11c919f0c593aa4880f51767182ed246 326 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 251 1.6E-32 T 14-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 D521_0325 11c919f0c593aa4880f51767182ed246 326 SUPERFAMILY SSF51735 1 319 7.71E-56 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0325 11c919f0c593aa4880f51767182ed246 326 Gene3D G3DSA:3.40.50.720 1 316 7.3E-57 T 14-10-2018 D521_0417 8657308ff5a4d68df25c373ace669dca 410 SUPERFAMILY SSF51412 33 401 5.04E-37 T 14-10-2018 D521_0417 8657308ff5a4d68df25c373ace669dca 410 Pfam PF03060 Nitronate monooxygenase 31 398 1.5E-37 T 14-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 D521_0417 8657308ff5a4d68df25c373ace669dca 410 Gene3D G3DSA:3.20.20.70 28 403 4.0E-50 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1128 8fa27d85ebba2592f83810f325234e01 273 SUPERFAMILY SSF53850 30 259 1.75E-30 T 14-10-2018 D521_1128 8fa27d85ebba2592f83810f325234e01 273 Pfam PF12849 PBP superfamily domain 25 251 3.4E-29 T 14-10-2018 IPR024370 PBP domain D521_1128 8fa27d85ebba2592f83810f325234e01 273 Gene3D G3DSA:3.40.190.10 107 220 5.1E-91 T 14-10-2018 D521_1128 8fa27d85ebba2592f83810f325234e01 273 Gene3D G3DSA:3.40.190.10 32 257 5.1E-91 T 14-10-2018 D521_0240 58104d70c5f98979c198bf79c0f1ef2a 488 Pfam PF01170 Putative RNA methylase family UPF0020 174 358 7.0E-33 T 14-10-2018 IPR000241 Putative RNA methylase domain D521_0240 58104d70c5f98979c198bf79c0f1ef2a 488 SUPERFAMILY SSF53335 153 474 1.97E-31 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0240 58104d70c5f98979c198bf79c0f1ef2a 488 Gene3D G3DSA:3.30.2130.30 4 293 1.0E-92 T 14-10-2018 D521_0240 58104d70c5f98979c198bf79c0f1ef2a 488 SMART SM00981 68 166 2.0E-22 T 14-10-2018 IPR004114 THUMP domain GO:0003723 D521_0240 58104d70c5f98979c198bf79c0f1ef2a 488 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 207 218 - T 14-10-2018 IPR000241 Putative RNA methylase domain D521_0240 58104d70c5f98979c198bf79c0f1ef2a 488 Pfam PF02926 THUMP domain 58 166 3.6E-10 T 14-10-2018 IPR004114 THUMP domain GO:0003723 D521_0240 58104d70c5f98979c198bf79c0f1ef2a 488 Gene3D G3DSA:3.40.50.150 181 357 1.0E-92 T 14-10-2018 D521_1933 643d02e9b0c42f8324149d3822fca4b3 284 Pfam PF00510 Cytochrome c oxidase subunit III 13 283 4.1E-55 T 14-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1933 643d02e9b0c42f8324149d3822fca4b3 284 Gene3D G3DSA:1.10.287.70 1 72 2.2E-8 T 14-10-2018 D521_1933 643d02e9b0c42f8324149d3822fca4b3 284 SUPERFAMILY SSF81452 7 284 2.49E-77 T 14-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1933 643d02e9b0c42f8324149d3822fca4b3 284 Gene3D G3DSA:1.20.120.80 74 284 8.4E-67 T 14-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_0800 db579f948a35114f9c5aa7638e99c955 582 PRINTS PR00113 Alkaline phosphatase signature 355 384 9.8E-35 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 D521_0800 db579f948a35114f9c5aa7638e99c955 582 PRINTS PR00113 Alkaline phosphatase signature 177 192 9.8E-35 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 D521_0800 db579f948a35114f9c5aa7638e99c955 582 PRINTS PR00113 Alkaline phosphatase signature 266 276 9.8E-35 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 D521_0800 db579f948a35114f9c5aa7638e99c955 582 PRINTS PR00113 Alkaline phosphatase signature 122 142 9.8E-35 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 D521_0800 db579f948a35114f9c5aa7638e99c955 582 PRINTS PR00113 Alkaline phosphatase signature 222 242 9.8E-35 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 D521_0800 db579f948a35114f9c5aa7638e99c955 582 SMART SM00098 123 577 1.6E-46 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 D521_0800 db579f948a35114f9c5aa7638e99c955 582 Pfam PF00245 Alkaline phosphatase 123 575 1.5E-77 T 14-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 D521_0800 db579f948a35114f9c5aa7638e99c955 582 SUPERFAMILY SSF53649 110 577 3.14E-113 T 14-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 D521_1856 9d34aea5427147ed338079fc61deb84d 507 SUPERFAMILY SSF56317 219 486 3.14E-29 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily D521_1856 9d34aea5427147ed338079fc61deb84d 507 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 11 493 20.067 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 D521_1856 9d34aea5427147ed338079fc61deb84d 507 Gene3D G3DSA:3.60.110.10 226 476 2.2E-10 T 14-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily D521_1856 9d34aea5427147ed338079fc61deb84d 507 Pfam PF00795 Carbon-nitrogen hydrolase 250 480 1.2E-22 T 14-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 D521_1856 9d34aea5427147ed338079fc61deb84d 507 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 67 455 5.8E-80 T 14-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 D521_0907 36af49875fec30ae9db173ba2a310b46 341 SUPERFAMILY SSF52540 7 335 2.39E-80 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0907 36af49875fec30ae9db173ba2a310b46 341 Gene3D G3DSA:3.40.50.300 55 271 3.1E-75 T 14-10-2018 D521_0907 36af49875fec30ae9db173ba2a310b46 341 Pfam PF03308 ArgK protein 25 302 3.9E-99 T 14-10-2018 D521_0907 36af49875fec30ae9db173ba2a310b46 341 Gene3D G3DSA:1.20.5.170 5 54 4.4E-11 T 14-10-2018 D521_0907 36af49875fec30ae9db173ba2a310b46 341 Gene3D G3DSA:1.10.287.130 274 338 2.1E-18 T 14-10-2018 D521_0907 36af49875fec30ae9db173ba2a310b46 341 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 21 331 2.5E-97 T 14-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 D521_0907 36af49875fec30ae9db173ba2a310b46 341 SMART SM00382 56 223 1.3E-4 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1877 99d1c6b46706056ef14373b7dd4cf64c 125 Gene3D G3DSA:2.60.300.12 19 125 2.1E-35 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 D521_1877 99d1c6b46706056ef14373b7dd4cf64c 125 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 1 125 36.373 T 14-10-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 D521_1877 99d1c6b46706056ef14373b7dd4cf64c 125 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 22 124 4.7E-39 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 D521_1877 99d1c6b46706056ef14373b7dd4cf64c 125 SUPERFAMILY SSF89360 18 111 1.16E-32 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 D521_1877 99d1c6b46706056ef14373b7dd4cf64c 125 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 106 123 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 D521_1877 99d1c6b46706056ef14373b7dd4cf64c 125 Pfam PF01521 Iron-sulphur cluster biosynthesis 20 120 4.1E-21 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 D521_0008 ac1f194e195e6ed4ef29dfe722aa262a 407 Pfam PF13458 Periplasmic binding protein 33 369 1.1E-88 T 14-10-2018 IPR028081 Leucine-binding protein domain D521_0008 ac1f194e195e6ed4ef29dfe722aa262a 407 SUPERFAMILY SSF53822 33 403 3.36E-90 T 14-10-2018 IPR028082 Periplasmic binding protein-like I D521_0008 ac1f194e195e6ed4ef29dfe722aa262a 407 Gene3D G3DSA:3.40.50.2300 154 285 2.1E-109 T 14-10-2018 D521_0008 ac1f194e195e6ed4ef29dfe722aa262a 407 Gene3D G3DSA:3.40.50.2300 33 336 2.1E-109 T 14-10-2018 D521_1760 0050c2bf877d7a0019862bb8990617d3 496 Gene3D G3DSA:3.30.2290.10 33 253 6.4E-17 T 14-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal D521_1760 0050c2bf877d7a0019862bb8990617d3 496 SUPERFAMILY SSF111283 38 495 1.29E-129 T 14-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 D521_1760 0050c2bf877d7a0019862bb8990617d3 496 Pfam PF01523 Putative modulator of DNA gyrase 54 347 1.0E-69 T 14-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 D521_1760 0050c2bf877d7a0019862bb8990617d3 496 PIRSF PIRSF004919 34 496 3.7E-130 T 14-10-2018 IPR025502 TldD D521_0605 1a0603a2f13a84080175fac77025453e 319 Gene3D G3DSA:2.40.128.130 26 175 3.6E-5 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily D521_0605 1a0603a2f13a84080175fac77025453e 319 SUPERFAMILY SSF103515 36 186 1.05E-6 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily D521_0687 48bba5994cf71135d193b99b80aa8ac0 268 Pfam PF01177 Asp/Glu/Hydantoin racemase 4 212 4.2E-37 T 14-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 D521_0687 48bba5994cf71135d193b99b80aa8ac0 268 Gene3D G3DSA:3.40.50.1860 4 249 6.8E-81 T 14-10-2018 D521_0687 48bba5994cf71135d193b99b80aa8ac0 268 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 177 187 - T 14-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 D521_0687 48bba5994cf71135d193b99b80aa8ac0 268 SUPERFAMILY SSF53681 107 255 1.28E-36 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 D521_0687 48bba5994cf71135d193b99b80aa8ac0 268 TIGRFAM TIGR00067 glut_race: glutamate racemase 4 248 3.9E-69 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 D521_0687 48bba5994cf71135d193b99b80aa8ac0 268 Hamap MF_00258 Glutamate racemase [murI]. 2 253 35.06 T 14-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 D521_0687 48bba5994cf71135d193b99b80aa8ac0 268 Gene3D G3DSA:3.40.50.1860 94 204 6.8E-81 T 14-10-2018 D521_0687 48bba5994cf71135d193b99b80aa8ac0 268 SUPERFAMILY SSF53681 4 104 5.75E-31 T 14-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 D521_1493 1f661a0c3f471931edbe73d242c48a08 162 SUPERFAMILY SSF74653 79 158 2.88E-18 T 14-10-2018 D521_1493 1f661a0c3f471931edbe73d242c48a08 162 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 85 160 3.4E-17 T 14-10-2018 IPR006260 TonB/TolA, C-terminal D521_1493 1f661a0c3f471931edbe73d242c48a08 162 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 83 160 1.0E-17 T 14-10-2018 IPR037682 TonB, C-terminal GO:0055085 D521_1493 1f661a0c3f471931edbe73d242c48a08 162 Gene3D G3DSA:3.30.1150.10 20 161 1.5E-18 T 14-10-2018 D521_0433 4b39859dc73ae3b5f979b3fc32f59efa 396 Pfam PF12704 MacB-like periplasmic core domain 17 250 6.0E-11 T 14-10-2018 IPR025857 MacB-like periplasmic core domain D521_0349 43b6004c4319fdf7996e6ca992bd981e 288 SUPERFAMILY SSF103481 33 128 9.42E-10 T 14-10-2018 D521_0349 43b6004c4319fdf7996e6ca992bd981e 288 SUPERFAMILY SSF103481 178 277 7.19E-9 T 14-10-2018 D521_0349 43b6004c4319fdf7996e6ca992bd981e 288 Pfam PF00892 EamA-like transporter family 1 125 3.7E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 D521_0349 43b6004c4319fdf7996e6ca992bd981e 288 Pfam PF00892 EamA-like transporter family 135 275 1.5E-10 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 D521_1997 a4e591e86d0d01916c5b80bd2b2f74d6 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 225 245 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1997 a4e591e86d0d01916c5b80bd2b2f74d6 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1997 a4e591e86d0d01916c5b80bd2b2f74d6 273 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 89 100 1.5E-12 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1997 a4e591e86d0d01916c5b80bd2b2f74d6 273 Gene3D G3DSA:3.40.50.720 10 271 2.0E-54 T 14-10-2018 D521_1997 a4e591e86d0d01916c5b80bd2b2f74d6 273 SUPERFAMILY SSF51735 11 261 1.54E-48 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1997 a4e591e86d0d01916c5b80bd2b2f74d6 273 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 260 7.6E-34 T 14-10-2018 D521_0648 b8e323f3edf4633c124cd42cc8609ff3 258 SUPERFAMILY SSF56436 50 257 1.16E-30 T 14-10-2018 IPR016187 C-type lectin fold D521_0648 b8e323f3edf4633c124cd42cc8609ff3 258 Gene3D G3DSA:3.90.1580.10 29 258 7.9E-31 T 14-10-2018 D521_0648 b8e323f3edf4633c124cd42cc8609ff3 258 Pfam PF03781 Sulfatase-modifying factor enzyme 1 51 257 4.8E-19 T 14-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 D521_0254 149622ea5bfcd5ae3ab7fa68eaa38a02 312 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 9 293 7.3E-154 T 14-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 D521_0254 149622ea5bfcd5ae3ab7fa68eaa38a02 312 SUPERFAMILY SSF53448 8 294 8.02E-91 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0254 149622ea5bfcd5ae3ab7fa68eaa38a02 312 Gene3D G3DSA:3.90.550.10 3 301 1.8E-84 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0254 149622ea5bfcd5ae3ab7fa68eaa38a02 312 Pfam PF00483 Nucleotidyl transferase 9 244 4.3E-68 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 D521_2113 1d9a060e27a30bf0a1b81f22a40b7183 402 Gene3D G3DSA:3.30.9.10 76 306 5.7E-60 T 14-10-2018 D521_2113 1d9a060e27a30bf0a1b81f22a40b7183 402 SUPERFAMILY SSF51905 1 355 6.99E-23 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_2113 1d9a060e27a30bf0a1b81f22a40b7183 402 Gene3D G3DSA:3.50.50.60 1 374 5.7E-60 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_2113 1d9a060e27a30bf0a1b81f22a40b7183 402 TIGRFAM TIGR03197 MnmC_Cterm: tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain 1 375 1.3E-59 T 14-10-2018 IPR017610 tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 D521_2113 1d9a060e27a30bf0a1b81f22a40b7183 402 Pfam PF01266 FAD dependent oxidoreductase 1 345 3.6E-31 T 14-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 SUPERFAMILY SSF48179 209 303 1.97E-30 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 PIRSF PIRSF000124 1 452 2.7E-147 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 Gene3D G3DSA:3.40.50.720 240 454 1.6E-81 T 14-10-2018 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 SMART SM00984 325 437 4.1E-50 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 183 2.4E-65 T 14-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 PIRSF PIRSF500134 1 454 1.3E-182 T 14-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 Gene3D G3DSA:1.20.5.100 208 238 3.1E-18 T 14-10-2018 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 209 301 6.7E-35 T 14-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 433 1.1E-129 T 14-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 325 436 4.3E-31 T 14-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 SUPERFAMILY SSF52413 312 447 5.1E-40 T 14-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 Gene3D G3DSA:3.40.50.720 1 207 2.4E-83 T 14-10-2018 D521_1474 2c92c6a32e26e0e7e61af4d274dca724 454 SUPERFAMILY SSF51735 2 199 6.81E-53 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0301 28ddb43f32c33b139022db1ea0fd1407 123 SUPERFAMILY SSF161084 3 122 6.41E-28 T 14-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily D521_0301 28ddb43f32c33b139022db1ea0fd1407 123 Gene3D G3DSA:1.20.120.550 1 123 6.6E-21 T 14-10-2018 IPR023352 Membrane associated eicosanoid/glutathione metabolism-like domain superfamily D521_0301 28ddb43f32c33b139022db1ea0fd1407 123 Pfam PF01124 MAPEG family 3 122 6.5E-25 T 14-10-2018 IPR001129 Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein D521_2047 4f5df2833bf157ea8edae054592276b8 186 SUPERFAMILY SSF52833 23 182 3.06E-23 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_2047 4f5df2833bf157ea8edae054592276b8 186 Gene3D G3DSA:3.40.30.10 27 182 2.8E-25 T 14-10-2018 D521_2047 4f5df2833bf157ea8edae054592276b8 186 Pfam PF08534 Redoxin 24 171 9.0E-21 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 D521_0201 7deb7e643a8c05de52c62b80d434700b 198 Pfam PF00293 NUDIX domain 7 135 2.1E-23 T 14-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 D521_0201 7deb7e643a8c05de52c62b80d434700b 198 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 161 37.714 T 14-10-2018 IPR022927 RNA pyrophosphohydrolase RppH D521_0201 7deb7e643a8c05de52c62b80d434700b 198 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 14-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 D521_0201 7deb7e643a8c05de52c62b80d434700b 198 Gene3D G3DSA:3.90.79.10 1 162 6.8E-44 T 14-10-2018 D521_0201 7deb7e643a8c05de52c62b80d434700b 198 PRINTS PR00502 NUDIX hydrolase family signature 47 62 3.8E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 D521_0201 7deb7e643a8c05de52c62b80d434700b 198 PRINTS PR00502 NUDIX hydrolase family signature 33 47 3.8E-7 T 14-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 D521_0201 7deb7e643a8c05de52c62b80d434700b 198 SUPERFAMILY SSF55811 4 164 4.6E-31 T 14-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 Gene3D G3DSA:3.90.780.10 382 574 2.9E-72 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 SUPERFAMILY SSF56300 40 381 1.29E-72 T 14-10-2018 D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 Gene3D G3DSA:3.60.21.10 95 381 2.6E-74 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 TIGRFAM TIGR04486 thiosulf_SoxB: thiosulfohydrolase SoxB 4 566 3.9E-264 T 14-10-2018 IPR030998 Thiosulfohydrolase SoxB D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 PRINTS PR01607 Apyrase family signature 268 285 1.6E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 PRINTS PR01607 Apyrase family signature 43 61 1.6E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 PRINTS PR01607 Apyrase family signature 287 310 1.6E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 PRINTS PR01607 Apyrase family signature 513 532 1.6E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 PRINTS PR01607 Apyrase family signature 319 339 1.6E-9 T 14-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 SUPERFAMILY SSF55816 379 565 1.07E-31 T 14-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 D521_0979 97b4b86c5db3707600d2cbbb6a4a1820 576 Pfam PF02872 5'-nucleotidase, C-terminal domain 398 523 3.3E-17 T 14-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 D521_1182 84ce02f70fa0387d1241bbb2893ad94d 66 Pfam PF04324 BFD-like [2Fe-2S] binding domain 4 49 1.2E-4 T 14-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain D521_1182 84ce02f70fa0387d1241bbb2893ad94d 66 Gene3D G3DSA:1.10.10.1100 4 57 1.5E-6 T 14-10-2018 D521_0656 b486c4077a97fa7d39df0e28bc02f537 282 Gene3D G3DSA:3.90.226.10 35 231 3.5E-14 T 14-10-2018 D521_0656 b486c4077a97fa7d39df0e28bc02f537 282 SUPERFAMILY SSF52096 51 194 7.56E-12 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_0541 374b7cbf17e37d7d84c8644b7ce09102 123 Pfam PF11162 Protein of unknown function (DUF2946) 11 120 3.1E-10 T 14-10-2018 IPR021333 Protein of unknown function DUF2946 D521_2111 e2603499ce5d46c96820955797f13db8 232 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 7 221 1.8E-71 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 D521_2111 e2603499ce5d46c96820955797f13db8 232 Gene3D G3DSA:3.40.50.450 1 227 4.4E-89 T 14-10-2018 D521_2111 e2603499ce5d46c96820955797f13db8 232 SUPERFAMILY SSF102405 13 221 7.33E-40 T 14-10-2018 D521_2111 e2603499ce5d46c96820955797f13db8 232 Pfam PF02481 DNA recombination-mediator protein A 11 212 4.5E-71 T 14-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 D521_1209 627ff29356315c9b887149d32d198e5b 154 Gene3D G3DSA:3.30.479.10 1 153 2.6E-33 T 14-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 D521_1209 627ff29356315c9b887149d32d198e5b 154 SUPERFAMILY SSF55620 9 151 1.28E-37 T 14-10-2018 D521_1209 627ff29356315c9b887149d32d198e5b 154 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 152 1.3E-35 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 D521_1209 627ff29356315c9b887149d32d198e5b 154 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 10 123 1.2E-26 T 14-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 D521_1662 0eec81e48afd6a96022027df30882924 478 SUPERFAMILY SSF56954 1 453 2.88E-44 T 14-10-2018 D521_1662 0eec81e48afd6a96022027df30882924 478 Pfam PF02321 Outer membrane efflux protein 145 247 1.7E-6 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_1662 0eec81e48afd6a96022027df30882924 478 Pfam PF02321 Outer membrane efflux protein 284 452 1.7E-7 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_1662 0eec81e48afd6a96022027df30882924 478 Gene3D G3DSA:1.20.1600.10 76 456 1.6E-30 T 14-10-2018 D521_0026 58dd587c53d64899897f87aed384671b 130 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 5 125 1.6E-38 T 14-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 D521_0026 58dd587c53d64899897f87aed384671b 130 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 129 36.842 T 14-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 D521_0026 58dd587c53d64899897f87aed384671b 130 SUPERFAMILY SSF51230 5 126 5.89E-32 T 14-10-2018 IPR011053 Single hybrid motif D521_0026 58dd587c53d64899897f87aed384671b 130 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 48 77 - T 14-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 D521_0026 58dd587c53d64899897f87aed384671b 130 Pfam PF01597 Glycine cleavage H-protein 8 124 1.7E-36 T 14-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate D521_0026 58dd587c53d64899897f87aed384671b 130 Gene3D G3DSA:2.40.50.100 1 127 1.8E-38 T 14-10-2018 D521_1519 9d83ad5f9e8145daa7cc374f4628636e 542 Pfam PF00916 Sulfate permease family 20 377 4.6E-83 T 14-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 D521_1519 9d83ad5f9e8145daa7cc374f4628636e 542 SUPERFAMILY SSF52091 439 540 1.79E-15 T 14-10-2018 IPR036513 STAS domain superfamily D521_1519 9d83ad5f9e8145daa7cc374f4628636e 542 Pfam PF01740 STAS domain 431 535 1.4E-13 T 14-10-2018 IPR002645 STAS domain D521_1519 9d83ad5f9e8145daa7cc374f4628636e 542 Gene3D G3DSA:3.30.750.24 419 542 4.0E-22 T 14-10-2018 IPR036513 STAS domain superfamily D521_0597 2b1e0b2fa68e2c4fb102bd7210e3f223 294 Gene3D G3DSA:3.10.129.10 173 293 9.1E-16 T 14-10-2018 D521_0597 2b1e0b2fa68e2c4fb102bd7210e3f223 294 Pfam PF13452 N-terminal half of MaoC dehydratase 20 146 1.4E-11 T 14-10-2018 IPR039569 N-terminal of MaoC-like dehydratase Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247|Reactome: R-HSA-9033241|Reactome: R-HSA-9033500 D521_0597 2b1e0b2fa68e2c4fb102bd7210e3f223 294 Gene3D G3DSA:3.10.129.10 45 163 6.5E-10 T 14-10-2018 D521_0597 2b1e0b2fa68e2c4fb102bd7210e3f223 294 SUPERFAMILY SSF54637 172 293 8.14E-16 T 14-10-2018 IPR029069 HotDog domain superfamily D521_0597 2b1e0b2fa68e2c4fb102bd7210e3f223 294 SUPERFAMILY SSF54637 82 159 7.46E-6 T 14-10-2018 IPR029069 HotDog domain superfamily D521_1758 c14a89fd24b23c02124db850d41ea4ea 1377 Pfam PF13116 Protein of unknown function 546 838 2.6E-43 T 14-10-2018 IPR025263 Domain of unknown function DUF3971 D521_1758 c14a89fd24b23c02124db850d41ea4ea 1377 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 31 1330 1.8E-157 T 14-10-2018 IPR011836 Conserved hypothetical protein CHP02099 D521_1758 c14a89fd24b23c02124db850d41ea4ea 1377 Pfam PF13502 AsmA-like C-terminal region 1076 1323 3.0E-47 T 14-10-2018 IPR032712 AsmA-like, C-terminal D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 3 471 19.283 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 Pfam PF03023 MviN-like protein 28 474 6.5E-126 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 PRINTS PR01806 Virulence factor MviN signature 132 156 8.7E-79 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 PRINTS PR01806 Virulence factor MviN signature 156 177 8.7E-79 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 PRINTS PR01806 Virulence factor MviN signature 363 382 8.7E-79 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 PRINTS PR01806 Virulence factor MviN signature 415 432 8.7E-79 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 PRINTS PR01806 Virulence factor MviN signature 33 52 8.7E-79 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 PRINTS PR01806 Virulence factor MviN signature 52 68 8.7E-79 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 PRINTS PR01806 Virulence factor MviN signature 265 291 8.7E-79 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 PIRSF PIRSF002869 1 517 3.5E-141 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1739 fc1afb818364b76e99e75afc98eb3a10 517 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 3 508 1.3E-134 T 14-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ D521_1455 6ca201daa335d3b40400d7f6a8baa899 131 PRINTS PR00061 Ribosomal protein L19 signature 92 117 2.0E-34 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1455 6ca201daa335d3b40400d7f6a8baa899 131 PRINTS PR00061 Ribosomal protein L19 signature 38 67 2.0E-34 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1455 6ca201daa335d3b40400d7f6a8baa899 131 PRINTS PR00061 Ribosomal protein L19 signature 8 37 2.0E-34 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1455 6ca201daa335d3b40400d7f6a8baa899 131 Gene3D G3DSA:2.30.30.790 2 122 2.7E-17 T 14-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1455 6ca201daa335d3b40400d7f6a8baa899 131 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 1 117 8.7E-49 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1455 6ca201daa335d3b40400d7f6a8baa899 131 SUPERFAMILY SSF50104 1 121 2.71E-44 T 14-10-2018 IPR008991 Translation protein SH3-like domain superfamily D521_1455 6ca201daa335d3b40400d7f6a8baa899 131 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 118 30.46 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1455 6ca201daa335d3b40400d7f6a8baa899 131 Pfam PF01245 Ribosomal protein L19 2 117 7.5E-47 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1455 6ca201daa335d3b40400d7f6a8baa899 131 ProSitePatterns PS01015 Ribosomal protein L19 signature. 90 105 - T 14-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1455 6ca201daa335d3b40400d7f6a8baa899 131 PIRSF PIRSF002191 1 131 5.0E-51 T 14-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1152 de0a4d61c2f020183a5cd5ab0616c775 382 Pfam PF00266 Aminotransferase class-V 22 293 4.0E-12 T 14-10-2018 IPR000192 Aminotransferase class V domain D521_1152 de0a4d61c2f020183a5cd5ab0616c775 382 SUPERFAMILY SSF53383 10 373 2.91E-72 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_1152 de0a4d61c2f020183a5cd5ab0616c775 382 Gene3D G3DSA:3.90.1150.10 271 368 1.1E-115 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_1152 de0a4d61c2f020183a5cd5ab0616c775 382 Gene3D G3DSA:3.40.640.10 38 270 1.1E-115 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_1152 de0a4d61c2f020183a5cd5ab0616c775 382 PIRSF PIRSF000524 17 382 8.8E-40 T 14-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 D521_1697 cef1cd3df1770c6fefc98236a3a8ef09 276 SUPERFAMILY SSF52821 156 275 5.89E-27 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1697 cef1cd3df1770c6fefc98236a3a8ef09 276 ProSitePatterns PS00380 Rhodanese signature 1. 39 50 - T 14-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 D521_1697 cef1cd3df1770c6fefc98236a3a8ef09 276 SMART SM00450 5 132 5.6E-17 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1697 cef1cd3df1770c6fefc98236a3a8ef09 276 SMART SM00450 153 272 4.6E-9 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1697 cef1cd3df1770c6fefc98236a3a8ef09 276 Gene3D G3DSA:3.40.250.10 156 276 2.2E-29 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1697 cef1cd3df1770c6fefc98236a3a8ef09 276 SUPERFAMILY SSF52821 2 139 2.1E-36 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1697 cef1cd3df1770c6fefc98236a3a8ef09 276 Pfam PF00581 Rhodanese-like domain 6 127 6.1E-18 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1697 cef1cd3df1770c6fefc98236a3a8ef09 276 Pfam PF00581 Rhodanese-like domain 154 268 2.4E-9 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1697 cef1cd3df1770c6fefc98236a3a8ef09 276 Gene3D G3DSA:3.40.250.10 1 146 1.6E-40 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1141 44c84ab44455ddb4307da818268a1530 174 Gene3D G3DSA:1.20.120.20 11 172 2.2E-6 T 14-10-2018 D521_1141 44c84ab44455ddb4307da818268a1530 174 Pfam PF09361 Phasin protein 5 100 2.0E-5 T 14-10-2018 IPR018968 Phasin D521_1141 44c84ab44455ddb4307da818268a1530 174 SUPERFAMILY SSF58113 25 163 3.92E-8 T 14-10-2018 D521_1956 6482668a8e72e209b2e9c5abe4cf2c7d 282 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 6 250 1.2E-47 T 14-10-2018 IPR010239 Conserved hypothetical protein CHP02001 D521_1956 6482668a8e72e209b2e9c5abe4cf2c7d 282 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 34 282 8.5E-55 T 14-10-2018 IPR010239 Conserved hypothetical protein CHP02001 D521_0525 9a51d498d09ec8562aac45541ce51d2a 467 Gene3D G3DSA:3.40.309.10 216 413 2.9E-142 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 D521_0525 9a51d498d09ec8562aac45541ce51d2a 467 Pfam PF00171 Aldehyde dehydrogenase family 22 433 1.1E-83 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 D521_0525 9a51d498d09ec8562aac45541ce51d2a 467 Gene3D G3DSA:3.40.605.10 15 433 2.9E-142 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 D521_0525 9a51d498d09ec8562aac45541ce51d2a 467 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 212 219 - T 14-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 D521_0525 9a51d498d09ec8562aac45541ce51d2a 467 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 240 251 - T 14-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 D521_0525 9a51d498d09ec8562aac45541ce51d2a 467 PIRSF PIRSF036492 1 467 1.4E-154 T 14-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 D521_0525 9a51d498d09ec8562aac45541ce51d2a 467 SUPERFAMILY SSF53720 11 434 3.8E-103 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 D521_1710 9e3ee91f7697e2883ecf886f5541488e 153 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 11 145 1.6E-20 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 D521_0990 0c2ea205c7ed2125ae71f83c5e03017b 207 Pfam PF13649 Methyltransferase domain 43 136 1.2E-12 T 14-10-2018 D521_0990 0c2ea205c7ed2125ae71f83c5e03017b 207 SUPERFAMILY SSF53335 4 183 7.64E-35 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0990 0c2ea205c7ed2125ae71f83c5e03017b 207 Gene3D G3DSA:3.40.50.150 9 207 5.7E-43 T 14-10-2018 D521_2119 3fe3b561570451815a9c04f8cebb30fd 44 Pfam PF00468 Ribosomal protein L34 1 44 4.2E-23 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_2119 3fe3b561570451815a9c04f8cebb30fd 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 42 5.0E-15 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_2119 3fe3b561570451815a9c04f8cebb30fd 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.028 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_2119 3fe3b561570451815a9c04f8cebb30fd 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.2E-24 T 14-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_2119 3fe3b561570451815a9c04f8cebb30fd 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 14-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1251 2637f2690614a954893551fe153735b8 351 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 6 343 1.7E-106 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 D521_1251 2637f2690614a954893551fe153735b8 351 Gene3D G3DSA:2.160.10.10 107 319 3.0E-54 T 14-10-2018 D521_1251 2637f2690614a954893551fe153735b8 351 SUPERFAMILY SSF51161 30 330 3.65E-74 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily D521_1251 2637f2690614a954893551fe153735b8 351 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 155 188 3.0E-8 T 14-10-2018 IPR001451 Hexapeptide repeat D521_1251 2637f2690614a954893551fe153735b8 351 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 125 152 3.5E-5 T 14-10-2018 IPR001451 Hexapeptide repeat D521_1251 2637f2690614a954893551fe153735b8 351 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 235 269 1.2E-6 T 14-10-2018 IPR001451 Hexapeptide repeat D521_1251 2637f2690614a954893551fe153735b8 351 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 7 340 35.147 T 14-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 D521_1251 2637f2690614a954893551fe153735b8 351 Gene3D G3DSA:3.40.1390.10 3 104 6.2E-21 T 14-10-2018 D521_1251 2637f2690614a954893551fe153735b8 351 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 22 96 1.4E-18 T 14-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 D521_0524 3f903377ee9a035da675c57551013078 514 SMART SM00487 31 237 4.3E-49 T 14-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain D521_0524 3f903377ee9a035da675c57551013078 514 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 168 176 - T 14-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site D521_0524 3f903377ee9a035da675c57551013078 514 SMART SM00490 274 355 6.2E-34 T 14-10-2018 IPR001650 Helicase, C-terminal D521_0524 3f903377ee9a035da675c57551013078 514 Pfam PF00271 Helicase conserved C-terminal domain 253 355 5.3E-27 T 14-10-2018 IPR001650 Helicase, C-terminal D521_0524 3f903377ee9a035da675c57551013078 514 Gene3D G3DSA:3.40.50.300 228 396 1.2E-48 T 14-10-2018 D521_0524 3f903377ee9a035da675c57551013078 514 SUPERFAMILY SSF52540 90 376 2.15E-67 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0524 3f903377ee9a035da675c57551013078 514 Pfam PF00270 DEAD/DEAH box helicase 36 207 6.2E-45 T 14-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 D521_0524 3f903377ee9a035da675c57551013078 514 Gene3D G3DSA:3.40.50.300 2 224 1.5E-69 T 14-10-2018 D521_0428 8b60ee79b23a79c1820326b6f7499958 233 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 227 4.6E-90 T 14-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 D521_0428 8b60ee79b23a79c1820326b6f7499958 233 Gene3D G3DSA:1.20.950.20 1 218 3.6E-78 T 14-10-2018 D521_0428 8b60ee79b23a79c1820326b6f7499958 233 Pfam PF02665 Nitrate reductase gamma subunit 5 226 1.6E-83 T 14-10-2018 IPR023234 NarG-like domain D521_0428 8b60ee79b23a79c1820326b6f7499958 233 SUPERFAMILY SSF103501 1 226 5.89E-69 T 14-10-2018 IPR036197 NarG-like superfamily D521_0160 6139036a23446323ce0a852c99a1c349 209 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 8 209 31.081 T 14-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 D521_0160 6139036a23446323ce0a852c99a1c349 209 SUPERFAMILY SSF47240 43 123 8.12E-17 T 14-10-2018 IPR009078 Ferritin-like superfamily D521_0160 6139036a23446323ce0a852c99a1c349 209 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 49 209 9.7E-43 T 14-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 D521_1613 03108a952a796f99adafc4f986642700 253 SUPERFAMILY SSF53474 63 248 1.09E-27 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1613 03108a952a796f99adafc4f986642700 253 Gene3D G3DSA:3.40.50.1820 61 250 1.1E-27 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1939 9ea6c0dcda1642a7b00c2516a334a96a 267 Gene3D G3DSA:3.40.50.150 52 170 5.6E-11 T 14-10-2018 D521_1939 9ea6c0dcda1642a7b00c2516a334a96a 267 SUPERFAMILY SSF53335 96 179 2.43E-12 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1939 9ea6c0dcda1642a7b00c2516a334a96a 267 Pfam PF08241 Methyltransferase domain 59 136 3.6E-10 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 D521_0032 40bf31e686b5c63b70862d55e3db9595 215 Pfam PF04972 BON domain 51 114 4.1E-7 T 14-10-2018 IPR007055 BON domain D521_0032 40bf31e686b5c63b70862d55e3db9595 215 Pfam PF04972 BON domain 124 185 1.8E-5 T 14-10-2018 IPR007055 BON domain D521_1349 b553bd3e664d29705cc19e75e6d070b8 107 Pfam PF01521 Iron-sulphur cluster biosynthesis 1 103 2.1E-27 T 14-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 D521_1349 b553bd3e664d29705cc19e75e6d070b8 107 SUPERFAMILY SSF89360 1 96 1.96E-32 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 D521_1349 b553bd3e664d29705cc19e75e6d070b8 107 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 88 105 - T 14-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 D521_1349 b553bd3e664d29705cc19e75e6d070b8 107 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 3 107 2.5E-37 T 14-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 D521_1349 b553bd3e664d29705cc19e75e6d070b8 107 Gene3D G3DSA:2.60.300.12 2 107 1.8E-37 T 14-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 D521_1349 b553bd3e664d29705cc19e75e6d070b8 107 TIGRFAM TIGR02011 IscA: iron-sulfur cluster assembly protein IscA 3 107 5.0E-52 T 14-10-2018 IPR011302 Iron-binding protein IscA, proteobacteria GO:0005506|GO:0051536|GO:0097428 D521_0440 ea17b0547f97bdc3139cbac17b995f69 798 SUPERFAMILY SSF53335 259 437 3.99E-8 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0440 ea17b0547f97bdc3139cbac17b995f69 798 Gene3D G3DSA:3.40.50.150 251 529 7.7E-7 T 14-10-2018 D521_1514 1d9a03aeff4dad9eb4913b0090017223 670 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 34 661 2.9E-159 T 14-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ D521_1514 1d9a03aeff4dad9eb4913b0090017223 670 Pfam PF11874 Domain of unknown function (DUF3394) 597 644 1.3E-7 T 14-10-2018 IPR021814 Protein of unknown function DUF3394 D521_1514 1d9a03aeff4dad9eb4913b0090017223 670 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 129 564 1.1E-67 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit D521_0594 c42ea328a9442935e4dbeb1a45dac83f 330 Gene3D G3DSA:3.40.190.150 33 321 7.5E-103 T 14-10-2018 D521_0594 c42ea328a9442935e4dbeb1a45dac83f 330 Gene3D G3DSA:3.40.190.10 130 253 7.5E-103 T 14-10-2018 D521_0594 c42ea328a9442935e4dbeb1a45dac83f 330 SUPERFAMILY SSF53850 119 291 5.65E-12 T 14-10-2018 D521_0594 c42ea328a9442935e4dbeb1a45dac83f 330 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 52 327 7.3E-80 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0594 c42ea328a9442935e4dbeb1a45dac83f 330 PIRSF PIRSF017082 1 330 1.2E-75 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0149 1ad3d5e91cead79bce17157e7c42ebae 501 Gene3D G3DSA:3.60.120.10 1 495 7.9E-168 T 14-10-2018 IPR005801 ADC synthase GO:0009058 D521_0149 1ad3d5e91cead79bce17157e7c42ebae 501 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 25 489 4.7E-164 T 14-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_0149 1ad3d5e91cead79bce17157e7c42ebae 501 Pfam PF00425 chorismate binding enzyme 225 481 2.7E-94 T 14-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal D521_0149 1ad3d5e91cead79bce17157e7c42ebae 501 SUPERFAMILY SSF56322 14 488 6.54E-150 T 14-10-2018 IPR005801 ADC synthase GO:0009058 D521_0149 1ad3d5e91cead79bce17157e7c42ebae 501 PRINTS PR00095 Anthranilate synthase component I signature 329 342 3.7E-24 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_0149 1ad3d5e91cead79bce17157e7c42ebae 501 PRINTS PR00095 Anthranilate synthase component I signature 438 452 3.7E-24 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_0149 1ad3d5e91cead79bce17157e7c42ebae 501 PRINTS PR00095 Anthranilate synthase component I signature 423 437 3.7E-24 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_0149 1ad3d5e91cead79bce17157e7c42ebae 501 PRINTS PR00095 Anthranilate synthase component I signature 343 356 3.7E-24 T 14-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_0149 1ad3d5e91cead79bce17157e7c42ebae 501 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 175 9.1E-30 T 14-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 D521_1252 38634f39c94fb43082dceeb691b544bc 175 SMART SM00935 18 172 5.8E-49 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 D521_1252 38634f39c94fb43082dceeb691b544bc 175 Pfam PF03938 Outer membrane protein (OmpH-like) 17 171 1.7E-30 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 D521_1252 38634f39c94fb43082dceeb691b544bc 175 Gene3D G3DSA:3.30.910.20 31 172 5.6E-33 T 14-10-2018 IPR024930 Skp domain superfamily D521_1252 38634f39c94fb43082dceeb691b544bc 175 SUPERFAMILY SSF111384 32 172 6.8E-31 T 14-10-2018 D521_1252 38634f39c94fb43082dceeb691b544bc 175 PIRSF PIRSF002094 6 175 8.4E-42 T 14-10-2018 IPR005632 Chaperone protein Skp GO:0051082 D521_0801 ed91cdc6a975d69f463d4b57561aa906 238 PRINTS PR01837 MgtC/SapB protein signature 67 89 1.6E-37 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 D521_0801 ed91cdc6a975d69f463d4b57561aa906 238 PRINTS PR01837 MgtC/SapB protein signature 41 59 1.6E-37 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 D521_0801 ed91cdc6a975d69f463d4b57561aa906 238 PRINTS PR01837 MgtC/SapB protein signature 22 41 1.6E-37 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 D521_0801 ed91cdc6a975d69f463d4b57561aa906 238 PRINTS PR01837 MgtC/SapB protein signature 94 118 1.6E-37 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 D521_0801 ed91cdc6a975d69f463d4b57561aa906 238 Pfam PF02308 MgtC family 19 138 3.3E-32 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 D521_1060 0145c71f2fbba52ed39e3d3010ddf0ff 229 SUPERFAMILY SSF53474 2 226 1.82E-41 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1060 0145c71f2fbba52ed39e3d3010ddf0ff 229 Pfam PF01738 Dienelactone hydrolase family 14 225 1.9E-55 T 14-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 D521_1060 0145c71f2fbba52ed39e3d3010ddf0ff 229 Gene3D G3DSA:3.40.50.1820 1 227 3.0E-49 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0529 f2f6b647e9854f5b2695e85ba5dfee90 460 PIRSF PIRSF006060 2 457 8.1E-67 T 14-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 D521_0529 f2f6b647e9854f5b2695e85ba5dfee90 460 Gene3D G3DSA:1.20.1740.10 8 459 2.0E-62 T 14-10-2018 D521_0529 f2f6b647e9854f5b2695e85ba5dfee90 460 ProSitePatterns PS00218 Amino acid permeases signature. 41 71 - T 14-10-2018 IPR004840 Amino acid permease, conserved site GO:0006865|GO:0016021|GO:0055085 D521_0529 f2f6b647e9854f5b2695e85ba5dfee90 460 Pfam PF00324 Amino acid permease 16 427 1.2E-110 T 14-10-2018 IPR004841 Amino acid permease/ SLC12A domain GO:0016020|GO:0055085 D521_1866 5e760154532cd040d954b59f9c4ba0db 238 Pfam PF00483 Nucleotidyl transferase 11 128 2.3E-17 T 14-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 D521_1866 5e760154532cd040d954b59f9c4ba0db 238 Gene3D G3DSA:3.90.550.10 9 238 1.5E-51 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1866 5e760154532cd040d954b59f9c4ba0db 238 SUPERFAMILY SSF53448 11 236 5.63E-48 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1961 850b2efb293b42ef7e7493d392ce7eb4 89 Gene3D G3DSA:3.30.70.260 1 89 1.0E-27 T 14-10-2018 D521_1961 850b2efb293b42ef7e7493d392ce7eb4 89 SUPERFAMILY SSF117991 2 89 6.15E-24 T 14-10-2018 IPR027471 YbeD-like domain superfamily D521_1961 850b2efb293b42ef7e7493d392ce7eb4 89 Pfam PF04359 Protein of unknown function (DUF493) 7 89 3.3E-26 T 14-10-2018 IPR007454 Uncharacterised protein family UPF0250 D521_1961 850b2efb293b42ef7e7493d392ce7eb4 89 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 1 89 20.315 T 14-10-2018 IPR007454 Uncharacterised protein family UPF0250 D521_0825 643b85fc40b983cbc7f924f4fe7bf482 198 SUPERFAMILY SSF52218 5 197 1.22E-57 T 14-10-2018 IPR029039 Flavoprotein-like superfamily D521_0825 643b85fc40b983cbc7f924f4fe7bf482 198 ProSitePatterns PS00201 Flavodoxin signature. 8 24 - T 14-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 D521_0825 643b85fc40b983cbc7f924f4fe7bf482 198 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 6 197 3.9E-48 T 14-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 D521_0825 643b85fc40b983cbc7f924f4fe7bf482 198 Gene3D G3DSA:3.40.50.360 1 197 1.5E-64 T 14-10-2018 IPR029039 Flavoprotein-like superfamily D521_0825 643b85fc40b983cbc7f924f4fe7bf482 198 Pfam PF03358 NADPH-dependent FMN reductase 15 143 5.3E-6 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 D521_0353 112e1530528239ef45a8da75d8cb6b29 242 SMART SM00382 26 217 9.1E-9 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_0353 112e1530528239ef45a8da75d8cb6b29 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_0353 112e1530528239ef45a8da75d8cb6b29 242 Gene3D G3DSA:3.40.50.300 1 239 6.9E-63 T 14-10-2018 D521_0353 112e1530528239ef45a8da75d8cb6b29 242 SUPERFAMILY SSF52540 2 236 1.96E-59 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0353 112e1530528239ef45a8da75d8cb6b29 242 Pfam PF00005 ABC transporter 17 166 8.1E-28 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_1134 0fc35e03cd033a3bfe5121e2dbdcd1da 196 Pfam PF05995 Cysteine dioxygenase type I 47 155 1.5E-5 T 14-10-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 D521_1134 0fc35e03cd033a3bfe5121e2dbdcd1da 196 SUPERFAMILY SSF51182 6 190 7.59E-50 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily D521_1134 0fc35e03cd033a3bfe5121e2dbdcd1da 196 Gene3D G3DSA:2.60.120.10 42 184 1.3E-51 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_1443 5da20e387160c944a212a26a0537d8ba 337 SUPERFAMILY SSF52283 13 146 1.25E-34 T 14-10-2018 D521_1443 5da20e387160c944a212a26a0537d8ba 337 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 161 188 - T 14-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 D521_1443 5da20e387160c944a212a26a0537d8ba 337 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 120 299 3.1E-59 T 14-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 D521_1443 5da20e387160c944a212a26a0537d8ba 337 Gene3D G3DSA:3.40.50.720 109 299 8.0E-113 T 14-10-2018 D521_1443 5da20e387160c944a212a26a0537d8ba 337 SUPERFAMILY SSF51735 114 299 2.46E-59 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1443 5da20e387160c944a212a26a0537d8ba 337 Gene3D G3DSA:3.40.50.720 15 326 8.0E-113 T 14-10-2018 D521_1443 5da20e387160c944a212a26a0537d8ba 337 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 16 331 7.0E-29 T 14-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 D521_0598 ee74add16c29407a3f3ed55cca27f482 441 PIRSF PIRSF004810 2 437 2.0E-121 T 14-10-2018 IPR014047 Chromate transporter, long chain D521_0598 ee74add16c29407a3f3ed55cca27f482 441 TIGRFAM TIGR00937 2A51: chromate efflux transporter 14 385 6.9E-71 T 14-10-2018 IPR014047 Chromate transporter, long chain D521_0598 ee74add16c29407a3f3ed55cca27f482 441 Pfam PF02417 Chromate transporter 10 170 1.9E-35 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 D521_0598 ee74add16c29407a3f3ed55cca27f482 441 Pfam PF02417 Chromate transporter 246 430 2.9E-33 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 D521_1498 308ac55c88083c3a79ed2463a837873a 100 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 2.1E-9 T 14-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain D521_1498 308ac55c88083c3a79ed2463a837873a 100 Gene3D G3DSA:3.30.70.100 1 96 1.7E-31 T 14-10-2018 D521_1498 308ac55c88083c3a79ed2463a837873a 100 SUPERFAMILY SSF54909 1 96 2.97E-21 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel D521_0180 7f402b00ce2a6ea129204f3fd877a4bd 411 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 411 155.542 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 D521_0180 7f402b00ce2a6ea129204f3fd877a4bd 411 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 24 409 1.0E-149 T 14-10-2018 D521_0180 7f402b00ce2a6ea129204f3fd877a4bd 411 Pfam PF01960 ArgJ family 22 411 9.6E-143 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 D521_0180 7f402b00ce2a6ea129204f3fd877a4bd 411 Gene3D G3DSA:3.10.20.340 282 411 6.5E-44 T 14-10-2018 D521_0180 7f402b00ce2a6ea129204f3fd877a4bd 411 Gene3D G3DSA:3.60.70.12 10 281 2.8E-91 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 D521_0180 7f402b00ce2a6ea129204f3fd877a4bd 411 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 15 411 1.1E-123 T 14-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 D521_0180 7f402b00ce2a6ea129204f3fd877a4bd 411 SUPERFAMILY SSF56266 16 408 5.23E-140 T 14-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 D521_1148 a428c1031cecee552120febf12a312af 293 Gene3D G3DSA:3.40.1190.20 12 292 6.5E-65 T 14-10-2018 IPR029056 Ribokinase-like D521_1148 a428c1031cecee552120febf12a312af 293 SUPERFAMILY SSF53613 13 292 3.52E-56 T 14-10-2018 IPR029056 Ribokinase-like D521_1148 a428c1031cecee552120febf12a312af 293 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 17 288 7.2E-55 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 D521_1148 a428c1031cecee552120febf12a312af 293 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 7 290 19.843 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 D521_1148 a428c1031cecee552120febf12a312af 293 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 224 234 - T 14-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site D521_1148 a428c1031cecee552120febf12a312af 293 Pfam PF01256 Carbohydrate kinase 30 280 2.9E-46 T 14-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 289 1.2E-100 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 289 35.314 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 Gene3D G3DSA:3.40.1380.10 61 208 1.1E-102 T 14-10-2018 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 275 288 - T 14-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 PRINTS PR00126 ATP synthase gamma subunit signature 267 288 1.5E-35 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 1.5E-35 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 1.5E-35 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 PRINTS PR00126 ATP synthase gamma subunit signature 236 255 1.5E-35 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 Pfam PF00231 ATP synthase 4 288 3.0E-93 T 14-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 SUPERFAMILY SSF52943 2 289 1.44E-93 T 14-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 D521_0021 e1884b523f8de1edeb16502f9e46e22f 289 Gene3D G3DSA:1.10.287.80 6 285 1.1E-102 T 14-10-2018 D521_1512 8520090e47ce15191ca630967b2d470a 308 PIRSF PIRSF001365 7 305 1.1E-51 T 14-10-2018 IPR002220 DapA-like GO:0016829 D521_1512 8520090e47ce15191ca630967b2d470a 308 SMART SM01130 9 302 5.0E-69 T 14-10-2018 IPR002220 DapA-like GO:0016829 D521_1512 8520090e47ce15191ca630967b2d470a 308 SUPERFAMILY SSF51569 13 303 7.43E-66 T 14-10-2018 D521_1512 8520090e47ce15191ca630967b2d470a 308 Gene3D G3DSA:3.20.20.70 11 304 4.6E-81 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_1512 8520090e47ce15191ca630967b2d470a 308 Pfam PF00701 Dihydrodipicolinate synthetase family 12 299 3.9E-40 T 14-10-2018 IPR002220 DapA-like GO:0016829 D521_0294 bb2985dff2fee7355e39968b3dc603cb 161 SUPERFAMILY SSF89963 2 87 5.23E-29 T 14-10-2018 IPR036183 YajQ-like superfamily D521_0294 bb2985dff2fee7355e39968b3dc603cb 161 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 161 26.997 T 14-10-2018 IPR007551 Protein of unknown function DUF520 D521_0294 bb2985dff2fee7355e39968b3dc603cb 161 Pfam PF04461 Protein of unknown function (DUF520) 2 160 7.7E-62 T 14-10-2018 IPR007551 Protein of unknown function DUF520 D521_0294 bb2985dff2fee7355e39968b3dc603cb 161 Gene3D G3DSA:3.30.70.860 3 160 2.1E-56 T 14-10-2018 IPR035571 UPF0234-like, C-terminal D521_0294 bb2985dff2fee7355e39968b3dc603cb 161 SUPERFAMILY SSF89963 89 161 3.92E-26 T 14-10-2018 IPR036183 YajQ-like superfamily D521_0294 bb2985dff2fee7355e39968b3dc603cb 161 Gene3D G3DSA:3.30.70.990 9 98 2.1E-56 T 14-10-2018 IPR035570 UPF0234, N-terminal D521_1719 2c2fcb131ae22e0dfa3ca2fd03cadff6 77 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 21.185 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1719 2c2fcb131ae22e0dfa3ca2fd03cadff6 77 Gene3D G3DSA:2.30.170.40 2 77 2.0E-31 T 14-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1719 2c2fcb131ae22e0dfa3ca2fd03cadff6 77 SUPERFAMILY SSF143800 2 74 3.34E-30 T 14-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1719 2c2fcb131ae22e0dfa3ca2fd03cadff6 77 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 9.5E-27 T 14-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1719 2c2fcb131ae22e0dfa3ca2fd03cadff6 77 Pfam PF00830 Ribosomal L28 family 3 62 6.1E-27 T 14-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1473 60cf5bcd03843b354d54f54a89928986 309 Gene3D G3DSA:3.40.1190.20 2 309 4.5E-124 T 14-10-2018 IPR029056 Ribokinase-like D521_1473 60cf5bcd03843b354d54f54a89928986 309 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 52 75 - T 14-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 D521_1473 60cf5bcd03843b354d54f54a89928986 309 Pfam PF00294 pfkB family carbohydrate kinase 12 302 2.9E-52 T 14-10-2018 IPR011611 Carbohydrate kinase PfkB D521_1473 60cf5bcd03843b354d54f54a89928986 309 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 7 309 5.2E-124 T 14-10-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 D521_1473 60cf5bcd03843b354d54f54a89928986 309 SUPERFAMILY SSF53613 12 308 7.79E-61 T 14-10-2018 IPR029056 Ribokinase-like D521_0014 2756345bfd5baa9ded412fefd1a777cf 295 Gene3D G3DSA:3.90.1530.30 43 105 4.9E-25 T 14-10-2018 D521_0014 2756345bfd5baa9ded412fefd1a777cf 295 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 28 204 1.1E-54 T 14-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 D521_0014 2756345bfd5baa9ded412fefd1a777cf 295 Pfam PF02195 ParB-like nuclease domain 32 119 8.9E-23 T 14-10-2018 IPR003115 ParB/Sulfiredoxin D521_0014 2756345bfd5baa9ded412fefd1a777cf 295 SUPERFAMILY SSF109709 113 218 7.32E-33 T 14-10-2018 D521_0014 2756345bfd5baa9ded412fefd1a777cf 295 Gene3D G3DSA:1.10.10.2830 107 219 2.4E-36 T 14-10-2018 D521_0014 2756345bfd5baa9ded412fefd1a777cf 295 SMART SM00470 30 120 1.4E-26 T 14-10-2018 IPR003115 ParB/Sulfiredoxin D521_0014 2756345bfd5baa9ded412fefd1a777cf 295 SUPERFAMILY SSF110849 31 122 1.62E-25 T 14-10-2018 IPR036086 ParB/Sulfiredoxin superfamily D521_1973 e22d088298b8ea46a6179d9310403cb3 220 SUPERFAMILY SSF52833 34 200 8.99E-41 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1973 e22d088298b8ea46a6179d9310403cb3 220 PIRSF PIRSF001488 8 218 3.0E-46 T 14-10-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL D521_1973 e22d088298b8ea46a6179d9310403cb3 220 ProSitePatterns PS00194 Thioredoxin family active site. 57 75 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 D521_1973 e22d088298b8ea46a6179d9310403cb3 220 Gene3D G3DSA:3.40.30.10 22 219 3.3E-53 T 14-10-2018 D521_1973 e22d088298b8ea46a6179d9310403cb3 220 Pfam PF01323 DSBA-like thioredoxin domain 104 191 1.9E-10 T 14-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 D521_0184 bea2ee19276ddaed8999efae62c706eb 220 SUPERFAMILY SSF52540 24 216 1.52E-37 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0184 bea2ee19276ddaed8999efae62c706eb 220 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 24 210 1.7E-51 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 D521_0184 bea2ee19276ddaed8999efae62c706eb 220 Pfam PF01121 Dephospho-CoA kinase 24 204 5.8E-56 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 D521_0184 bea2ee19276ddaed8999efae62c706eb 220 Gene3D G3DSA:3.40.50.300 2 220 7.0E-67 T 14-10-2018 D521_0184 bea2ee19276ddaed8999efae62c706eb 220 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 22 220 27.024 T 14-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 D521_0669 809cb0f0e157b6fd8a6011903173351d 329 PIRSF PIRSF017082 1 328 6.8E-69 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0669 809cb0f0e157b6fd8a6011903173351d 329 Gene3D G3DSA:3.40.190.150 33 319 1.4E-98 T 14-10-2018 D521_0669 809cb0f0e157b6fd8a6011903173351d 329 SUPERFAMILY SSF53850 112 290 1.25E-10 T 14-10-2018 D521_0669 809cb0f0e157b6fd8a6011903173351d 329 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 53 325 1.3E-75 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0669 809cb0f0e157b6fd8a6011903173351d 329 Gene3D G3DSA:3.40.190.10 131 254 1.4E-98 T 14-10-2018 D521_2073 6895641a5ce6d78fe4c5a40ab3c47b1a 187 Pfam PF13280 WYL domain 17 184 3.3E-39 T 14-10-2018 IPR026881 WYL domain D521_1791 ea3de6a91615ab9f8cd1b27ce01c93b2 239 Gene3D G3DSA:3.40.50.300 2 238 2.4E-53 T 14-10-2018 D521_1791 ea3de6a91615ab9f8cd1b27ce01c93b2 239 SUPERFAMILY SSF52540 6 223 5.43E-53 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1791 ea3de6a91615ab9f8cd1b27ce01c93b2 239 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 14-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 D521_1791 ea3de6a91615ab9f8cd1b27ce01c93b2 239 Pfam PF00005 ABC transporter 23 167 1.2E-29 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_1791 ea3de6a91615ab9f8cd1b27ce01c93b2 239 SMART SM00382 31 214 2.9E-6 T 14-10-2018 IPR003593 AAA+ ATPase domain D521_1795 325ca4107acc53e74a7a91376b238438 415 SUPERFAMILY SSF53822 30 392 4.54E-80 T 14-10-2018 IPR028082 Periplasmic binding protein-like I D521_1795 325ca4107acc53e74a7a91376b238438 415 Gene3D G3DSA:3.40.50.2300 149 373 1.1E-100 T 14-10-2018 D521_1795 325ca4107acc53e74a7a91376b238438 415 Gene3D G3DSA:3.40.50.2300 31 361 1.1E-100 T 14-10-2018 D521_1795 325ca4107acc53e74a7a91376b238438 415 Pfam PF13458 Periplasmic binding protein 30 373 1.7E-67 T 14-10-2018 IPR028081 Leucine-binding protein domain D521_1937 e5ca9d55567edf33d02358465a135756 539 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 35 475 1.5E-150 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 254 308 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 27 530 7.2E-209 T 14-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 26 51 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 172 190 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 357 375 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 322 343 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 252 273 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 298 313 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 100 124 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 143 155 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 435 456 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 201 220 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 385 404 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 PRINTS PR01165 Cytochrome c oxidase subunit I signature 73 96 2.7E-121 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 Gene3D G3DSA:1.20.210.10 14 536 1.3E-215 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1937 e5ca9d55567edf33d02358465a135756 539 SUPERFAMILY SSF81442 23 530 2.88E-191 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1440 53cd669c7f4de50896ea4b9f4648e7a5 201 Gene3D G3DSA:3.90.550.10 2 200 1.3E-47 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1440 53cd669c7f4de50896ea4b9f4648e7a5 201 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 5 196 28.053 T 14-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 D521_1440 53cd669c7f4de50896ea4b9f4648e7a5 201 Pfam PF12804 MobA-like NTP transferase domain 9 170 1.6E-29 T 14-10-2018 IPR025877 MobA-like NTP transferase D521_1440 53cd669c7f4de50896ea4b9f4648e7a5 201 SUPERFAMILY SSF53448 7 196 3.11E-30 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1440 53cd669c7f4de50896ea4b9f4648e7a5 201 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 7 194 1.6E-62 T 14-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 D521_1931 9bef61d4ee1efd4ca78f0c55b651f947 260 Pfam PF02104 SURF1 family 20 235 6.1E-29 T 14-10-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_2024 356d965db155586ec3dd26031b736c81 280 PIRSF PIRSF038471 1 258 2.6E-54 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 D521_2024 356d965db155586ec3dd26031b736c81 280 Gene3D G3DSA:2.40.10.350 155 232 1.2E-26 T 14-10-2018 D521_2024 356d965db155586ec3dd26031b736c81 280 Gene3D G3DSA:2.40.10.340 98 239 1.2E-26 T 14-10-2018 D521_2024 356d965db155586ec3dd26031b736c81 280 Pfam PF04085 rod shape-determining protein MreC 99 240 2.7E-29 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 D521_2024 356d965db155586ec3dd26031b736c81 280 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 3 243 2.7E-38 T 14-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 D521_1822 e806c5ad5275181326552b1587abc2ee 610 SUPERFAMILY SSF103515 312 592 2.09E-15 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily D521_1822 e806c5ad5275181326552b1587abc2ee 610 Gene3D G3DSA:2.40.128.130 298 593 1.7E-15 T 14-10-2018 IPR036709 Autotransporter beta-domain superfamily D521_1822 e806c5ad5275181326552b1587abc2ee 610 SMART SM00869 340 598 2.4E-4 T 14-10-2018 IPR005546 Autotransporter beta-domain D521_1818 7c5626c6fdf97105f7414035149bc530 556 Gene3D G3DSA:1.25.40.10 298 550 2.3E-14 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1818 7c5626c6fdf97105f7414035149bc530 556 Pfam PF14559 Tetratricopeptide repeat 417 476 3.2E-8 T 14-10-2018 D521_1818 7c5626c6fdf97105f7414035149bc530 556 Pfam PF01435 Peptidase family M48 141 309 5.8E-31 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 D521_1818 7c5626c6fdf97105f7414035149bc530 556 SUPERFAMILY SSF48452 362 490 2.47E-13 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_2010 c77906c9fab0a46e5caab382410de7ad 260 SUPERFAMILY SSF56219 2 257 2.36E-72 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily D521_2010 c77906c9fab0a46e5caab382410de7ad 260 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 29 38 - T 14-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 D521_2010 c77906c9fab0a46e5caab382410de7ad 260 Gene3D G3DSA:3.60.10.10 1 259 1.1E-80 T 14-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily D521_2010 c77906c9fab0a46e5caab382410de7ad 260 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 254 4.3E-70 T 14-10-2018 D521_2010 c77906c9fab0a46e5caab382410de7ad 260 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 249 1.4E-13 T 14-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase D521_2010 c77906c9fab0a46e5caab382410de7ad 260 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 256 3.3E-75 T 14-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 D521_0908 72627151ebbb559ee091964fae72c41a 510 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 180 3.0E-5 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0908 72627151ebbb559ee091964fae72c41a 510 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 127 145 3.0E-5 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0908 72627151ebbb559ee091964fae72c41a 510 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 93 107 3.0E-5 T 14-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 D521_0908 72627151ebbb559ee091964fae72c41a 510 SUPERFAMILY SSF52096 223 510 3.11E-88 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_0908 72627151ebbb559ee091964fae72c41a 510 Pfam PF01039 Carboxyl transferase domain 27 508 1.5E-195 T 14-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 D521_0908 72627151ebbb559ee091964fae72c41a 510 Gene3D G3DSA:3.90.226.10 1 256 1.7E-98 T 14-10-2018 D521_0908 72627151ebbb559ee091964fae72c41a 510 Gene3D G3DSA:3.90.226.10 259 510 2.4E-92 T 14-10-2018 D521_0908 72627151ebbb559ee091964fae72c41a 510 SUPERFAMILY SSF52096 3 254 1.03E-81 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_2008 5acd08c467d649c99da29edb2c75899b 300 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 76 90 - T 14-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 D521_2008 5acd08c467d649c99da29edb2c75899b 300 SUPERFAMILY SSF54506 11 298 3.22E-51 T 14-10-2018 D521_2008 5acd08c467d649c99da29edb2c75899b 300 Gene3D G3DSA:3.10.310.10 14 296 8.0E-94 T 14-10-2018 D521_2008 5acd08c467d649c99da29edb2c75899b 300 Gene3D G3DSA:3.10.310.10 127 287 8.0E-94 T 14-10-2018 D521_2008 5acd08c467d649c99da29edb2c75899b 300 Pfam PF01678 Diaminopimelate epimerase 14 134 1.8E-31 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 D521_2008 5acd08c467d649c99da29edb2c75899b 300 Pfam PF01678 Diaminopimelate epimerase 174 291 3.2E-27 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 D521_2008 5acd08c467d649c99da29edb2c75899b 300 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 13 298 8.4E-86 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 D521_2008 5acd08c467d649c99da29edb2c75899b 300 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 12 300 36.734 T 14-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 D521_0167 ec574ecb726021872a975bdfb7620593 389 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 4.0E-6 T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0167 ec574ecb726021872a975bdfb7620593 389 Pfam PF00953 Glycosyl transferase family 4 99 307 2.7E-34 T 14-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 D521_0167 ec574ecb726021872a975bdfb7620593 389 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 387 23.593 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0167 ec574ecb726021872a975bdfb7620593 389 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 180 389 1.5E-82 T 14-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0167 ec574ecb726021872a975bdfb7620593 389 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_0167 ec574ecb726021872a975bdfb7620593 389 ProSitePatterns PS01348 MraY family signature 2. 212 223 - T 14-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_1516 ffcf3741caddc0308d9dc342851fef36 478 SUPERFAMILY SSF51261 293 446 2.04E-41 T 14-10-2018 IPR011055 Duplicated hybrid motif D521_1516 ffcf3741caddc0308d9dc342851fef36 478 Pfam PF01551 Peptidase family M23 349 445 1.3E-31 T 14-10-2018 IPR016047 Peptidase M23 D521_1516 ffcf3741caddc0308d9dc342851fef36 478 Gene3D G3DSA:2.70.70.10 308 451 1.1E-39 T 14-10-2018 IPR011055 Duplicated hybrid motif D521_1545 a3ad3fb86d3593949f0bd8e9716adbe4 251 SMART SM00062 17 237 1.0E-13 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF D521_1545 a3ad3fb86d3593949f0bd8e9716adbe4 251 Gene3D G3DSA:3.40.190.10 104 196 1.1E-22 T 14-10-2018 D521_1545 a3ad3fb86d3593949f0bd8e9716adbe4 251 SUPERFAMILY SSF53850 34 234 7.24E-29 T 14-10-2018 D521_1545 a3ad3fb86d3593949f0bd8e9716adbe4 251 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 233 2.9E-20 T 14-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF D521_1545 a3ad3fb86d3593949f0bd8e9716adbe4 251 Gene3D G3DSA:3.40.190.10 32 226 1.1E-22 T 14-10-2018 D521_2027 b4c2917c2034af785b120476c88dc7a4 383 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 23 378 1.5E-124 T 14-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_2027 b4c2917c2034af785b120476c88dc7a4 383 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 336 360 - T 14-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_2027 b4c2917c2034af785b120476c88dc7a4 383 Pfam PF01098 Cell cycle protein 25 379 4.1E-98 T 14-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_2027 b4c2917c2034af785b120476c88dc7a4 383 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 15 381 26.612 T 14-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 D521_1631 d7928d7ee226c0dd797cf2e60cb9a8f2 382 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 26 351 1.8E-38 T 14-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal D521_1631 d7928d7ee226c0dd797cf2e60cb9a8f2 382 SUPERFAMILY SSF56235 26 355 5.09E-63 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_1631 d7928d7ee226c0dd797cf2e60cb9a8f2 382 Gene3D G3DSA:3.60.60.10 26 373 1.2E-74 T 14-10-2018 D521_1142 c27cae7ada3c948efac65fd6b9342f96 129 Pfam PF01152 Bacterial-like globin 8 125 8.4E-38 T 14-10-2018 IPR001486 Truncated hemoglobin GO:0019825 D521_1142 c27cae7ada3c948efac65fd6b9342f96 129 Gene3D G3DSA:1.10.490.10 3 129 2.5E-43 T 14-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 D521_1142 c27cae7ada3c948efac65fd6b9342f96 129 SUPERFAMILY SSF46458 7 127 2.88E-34 T 14-10-2018 IPR009050 Globin-like superfamily D521_0125 bdd672fb0e777ca7365af4c845efa822 133 Pfam PF04386 Stringent starvation protein B 7 121 4.6E-32 T 14-10-2018 IPR007481 Stringent starvation protein B D521_0125 bdd672fb0e777ca7365af4c845efa822 133 SUPERFAMILY SSF101738 3 116 6.28E-44 T 14-10-2018 IPR036760 SspB-like superfamily D521_0125 bdd672fb0e777ca7365af4c845efa822 133 Gene3D G3DSA:2.30.30.220 2 125 2.3E-45 T 14-10-2018 IPR036760 SspB-like superfamily D521_0125 bdd672fb0e777ca7365af4c845efa822 133 PIRSF PIRSF005276 1 133 3.2E-48 T 14-10-2018 IPR007481 Stringent starvation protein B D521_0126 ab7493e802512e752924bdc2215bf1a0 493 Pfam PF13414 TPR repeat 80 119 5.9E-7 T 14-10-2018 D521_0126 ab7493e802512e752924bdc2215bf1a0 493 Pfam PF13414 TPR repeat 122 155 1.9E-11 T 14-10-2018 D521_0126 ab7493e802512e752924bdc2215bf1a0 493 SUPERFAMILY SSF53756 230 464 1.0E-6 T 14-10-2018 D521_0126 ab7493e802512e752924bdc2215bf1a0 493 Pfam PF13432 Tetratricopeptide repeat 9 66 0.0037 T 14-10-2018 D521_0126 ab7493e802512e752924bdc2215bf1a0 493 Gene3D G3DSA:1.25.40.10 1 199 2.4E-41 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0126 ab7493e802512e752924bdc2215bf1a0 493 SUPERFAMILY SSF48452 5 179 2.28E-36 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0126 ab7493e802512e752924bdc2215bf1a0 493 SMART SM00028 39 72 0.79 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0126 ab7493e802512e752924bdc2215bf1a0 493 SMART SM00028 73 106 0.022 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0126 ab7493e802512e752924bdc2215bf1a0 493 SMART SM00028 141 174 3.6E-5 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0126 ab7493e802512e752924bdc2215bf1a0 493 SMART SM00028 107 140 1.6E-8 T 14-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 9.5E-47 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 Gene3D G3DSA:1.10.1900.20 56 119 8.9E-28 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 SUPERFAMILY SSF74731 2 115 1.02E-47 T 14-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 72 7.0E-21 T 14-10-2018 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.86 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 PRINTS PR00062 Ribosomal protein L20 signature 75 101 4.3E-37 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 PRINTS PR00062 Ribosomal protein L20 signature 42 71 4.3E-37 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 PRINTS PR00062 Ribosomal protein L20 signature 12 41 4.3E-37 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 Pfam PF00453 Ribosomal protein L20 3 109 1.0E-47 T 14-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0838 6d60e76cf3c89d54508b41f9f7641af9 121 Gene3D G3DSA:1.10.720.90 2 55 6.3E-24 T 14-10-2018 D521_1249 c7d47ed86368687d24e7aaeefbbf0608 265 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 105 139 1.3E-9 T 14-10-2018 IPR001451 Hexapeptide repeat D521_1249 c7d47ed86368687d24e7aaeefbbf0608 265 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 48 6.7E-11 T 14-10-2018 IPR001451 Hexapeptide repeat D521_1249 c7d47ed86368687d24e7aaeefbbf0608 265 PIRSF PIRSF000456 1 265 3.4E-104 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 D521_1249 c7d47ed86368687d24e7aaeefbbf0608 265 SUPERFAMILY SSF51161 2 264 3.21E-75 T 14-10-2018 IPR011004 Trimeric LpxA-like superfamily D521_1249 c7d47ed86368687d24e7aaeefbbf0608 265 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 265 46.12 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 D521_1249 c7d47ed86368687d24e7aaeefbbf0608 265 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 4 263 3.0E-103 T 14-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 D521_1249 c7d47ed86368687d24e7aaeefbbf0608 265 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 176 264 2.5E-29 T 14-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 D521_1249 c7d47ed86368687d24e7aaeefbbf0608 265 Gene3D G3DSA:1.20.1180.10 193 265 5.3E-24 T 14-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 D521_1249 c7d47ed86368687d24e7aaeefbbf0608 265 Gene3D G3DSA:2.160.10.10 1 189 8.5E-52 T 14-10-2018 D521_0869 2e2b9253da0960f24afc96ea7a8bb518 438 Gene3D G3DSA:3.90.1300.10 10 436 2.9E-120 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 D521_0869 2e2b9253da0960f24afc96ea7a8bb518 438 SUPERFAMILY SSF75304 27 435 3.14E-108 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 D521_0869 2e2b9253da0960f24afc96ea7a8bb518 438 Pfam PF01425 Amidase 56 424 2.2E-81 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 D521_0542 1d39968757a22ec42fad13744f722368 138 Gene3D G3DSA:3.40.1260.10 26 134 3.5E-12 T 14-10-2018 IPR027396 DsrEFH-like D521_0542 1d39968757a22ec42fad13744f722368 138 SUPERFAMILY SSF75169 30 131 1.01E-12 T 14-10-2018 IPR027396 DsrEFH-like D521_0542 1d39968757a22ec42fad13744f722368 138 Pfam PF02635 DsrE/DsrF-like family 37 122 6.1E-7 T 14-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein D521_2084 02aa6bee7760a14b9a5d4b56a0a93539 404 Pfam PF00589 Phage integrase family 202 393 1.9E-9 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 D521_2084 02aa6bee7760a14b9a5d4b56a0a93539 404 SUPERFAMILY SSF56349 104 401 8.54E-31 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_2084 02aa6bee7760a14b9a5d4b56a0a93539 404 Gene3D G3DSA:1.10.150.130 85 198 1.0E-5 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal D521_2084 02aa6bee7760a14b9a5d4b56a0a93539 404 Gene3D G3DSA:1.10.443.10 201 404 1.5E-20 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 D521_1797 f4870e15caeee064e6b52f1415462ad3 506 Gene3D G3DSA:3.40.309.10 261 455 4.2E-167 T 14-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 D521_1797 f4870e15caeee064e6b52f1415462ad3 506 Pfam PF00171 Aldehyde dehydrogenase family 28 484 2.3E-159 T 14-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 D521_1797 f4870e15caeee064e6b52f1415462ad3 506 Gene3D G3DSA:3.40.605.10 28 484 4.2E-167 T 14-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 D521_1797 f4870e15caeee064e6b52f1415462ad3 506 SUPERFAMILY SSF53720 6 488 5.76E-156 T 14-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 D521_1656 4ee2b42ade229bce7d1cdf60d7204d47 200 Pfam PF04011 LemA family 8 194 2.9E-66 T 14-10-2018 IPR007156 LemA D521_1656 4ee2b42ade229bce7d1cdf60d7204d47 200 SUPERFAMILY SSF140478 25 181 8.24E-54 T 14-10-2018 IPR023353 LemA-like domain superfamily D521_1656 4ee2b42ade229bce7d1cdf60d7204d47 200 Gene3D G3DSA:1.20.1440.20 16 194 8.2E-61 T 14-10-2018 IPR023353 LemA-like domain superfamily D521_2069 466490e4a554c33c49af972ab6a4a745 204 SUPERFAMILY SSF53335 2 154 1.37E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_2069 466490e4a554c33c49af972ab6a4a745 204 Pfam PF08241 Methyltransferase domain 46 144 2.3E-12 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 D521_2069 466490e4a554c33c49af972ab6a4a745 204 Gene3D G3DSA:3.40.50.150 2 179 1.6E-25 T 14-10-2018 D521_1401 3450085b4ea7af2e1d5978faeb885dcb 51 Gene3D G3DSA:2.40.50.140 1 51 5.3E-10 T 14-10-2018 D521_1450 085b4a56195a2278008ea20311b583db 207 SUPERFAMILY SSF53218 15 203 3.01E-43 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily D521_1450 085b4a56195a2278008ea20311b583db 207 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 15 161 1.0E-34 T 14-10-2018 IPR001453 MoaB/Mog domain D521_1450 085b4a56195a2278008ea20311b583db 207 Gene3D G3DSA:3.40.980.10 13 207 8.8E-58 T 14-10-2018 IPR036425 MoaB/Mog-like domain superfamily D521_1450 085b4a56195a2278008ea20311b583db 207 Pfam PF00994 Probable molybdopterin binding domain 19 162 4.1E-28 T 14-10-2018 IPR001453 MoaB/Mog domain D521_1450 085b4a56195a2278008ea20311b583db 207 SMART SM00852 18 169 1.2E-22 T 14-10-2018 IPR001453 MoaB/Mog domain D521_1450 085b4a56195a2278008ea20311b583db 207 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 80 93 - T 14-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 D521_0477 c6ee5a4935b4c9dd81315a50c4715dcb 385 SUPERFAMILY SSF53756 10 381 3.77E-66 T 14-10-2018 D521_0477 c6ee5a4935b4c9dd81315a50c4715dcb 385 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 144 319 5.5E-30 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 D521_0477 c6ee5a4935b4c9dd81315a50c4715dcb 385 Gene3D G3DSA:3.40.50.2000 4 169 5.2E-19 T 14-10-2018 D521_0477 c6ee5a4935b4c9dd81315a50c4715dcb 385 Gene3D G3DSA:3.40.50.2000 191 385 2.7E-37 T 14-10-2018 D521_0196 95b9ae906e23ad9db1f0e297932fa79c 84 ProSitePatterns PS01169 Ribosomal protein L21 signature. 53 75 - T 14-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0196 95b9ae906e23ad9db1f0e297932fa79c 84 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 82 8.7E-27 T 14-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0196 95b9ae906e23ad9db1f0e297932fa79c 84 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 82 1.3E-28 T 14-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0196 95b9ae906e23ad9db1f0e297932fa79c 84 SUPERFAMILY SSF141091 2 82 1.57E-27 T 14-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0725 ed618783dfec9c2e56c64f491ff8d155 304 Pfam PF02470 MlaD protein 49 136 3.7E-14 T 14-10-2018 IPR003399 Mce/MlaD D521_1254 8f30b02727591a92a520b3854e20cf9c 377 Pfam PF02163 Peptidase family M50 9 362 2.3E-70 T 14-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 D521_0850 9e5a4b9a066a7c4ba4ad5198dc6b046e 282 Pfam PF02811 PHP domain 10 124 7.0E-7 T 14-10-2018 IPR004013 PHP domain GO:0003824 D521_0850 9e5a4b9a066a7c4ba4ad5198dc6b046e 282 Gene3D G3DSA:3.20.20.140 10 255 7.8E-83 T 14-10-2018 D521_0850 9e5a4b9a066a7c4ba4ad5198dc6b046e 282 Gene3D G3DSA:1.10.150.650 102 174 7.8E-83 T 14-10-2018 D521_0850 9e5a4b9a066a7c4ba4ad5198dc6b046e 282 SUPERFAMILY SSF89550 8 278 1.96E-48 T 14-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 D521_0850 9e5a4b9a066a7c4ba4ad5198dc6b046e 282 SMART SM00481 9 74 8.4E-13 T 14-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal D521_1694 f34dcdd6eec6387b398f9181f6efac45 297 Gene3D G3DSA:1.10.600.10 2 297 2.2E-92 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily D521_1694 f34dcdd6eec6387b398f9181f6efac45 297 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 216 228 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site D521_1694 f34dcdd6eec6387b398f9181f6efac45 297 SUPERFAMILY SSF48576 6 286 3.17E-84 T 14-10-2018 IPR008949 Isoprenoid synthase domain superfamily D521_1694 f34dcdd6eec6387b398f9181f6efac45 297 Pfam PF00348 Polyprenyl synthetase 35 272 2.0E-56 T 14-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 D521_1694 f34dcdd6eec6387b398f9181f6efac45 297 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 86 102 - T 14-10-2018 IPR033749 Polyprenyl synthetase, conserved site D521_1386 4d7485466544751e9b4f3ae216511714 125 SUPERFAMILY SSF64076 2 122 7.06E-37 T 14-10-2018 IPR036748 MTH938-like superfamily D521_1386 4d7485466544751e9b4f3ae216511714 125 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 14 121 5.7E-32 T 14-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein D521_1386 4d7485466544751e9b4f3ae216511714 125 Gene3D G3DSA:3.40.1230.10 1 124 3.0E-40 T 14-10-2018 IPR036748 MTH938-like superfamily D521_0142 79620e058c1801769c7f889bcd7b4fb6 424 Gene3D G3DSA:3.50.50.60 23 367 8.5E-85 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0142 79620e058c1801769c7f889bcd7b4fb6 424 Pfam PF01494 FAD binding domain 22 367 1.0E-25 T 14-10-2018 IPR002938 FAD-binding domain GO:0071949 D521_0142 79620e058c1801769c7f889bcd7b4fb6 424 Gene3D G3DSA:3.30.9.50 100 295 8.5E-85 T 14-10-2018 D521_0142 79620e058c1801769c7f889bcd7b4fb6 424 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 325 341 9.7E-21 T 14-10-2018 D521_0142 79620e058c1801769c7f889bcd7b4fb6 424 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 177 192 9.7E-21 T 14-10-2018 D521_0142 79620e058c1801769c7f889bcd7b4fb6 424 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 23 45 9.7E-21 T 14-10-2018 D521_0142 79620e058c1801769c7f889bcd7b4fb6 424 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 310 325 9.7E-21 T 14-10-2018 D521_0142 79620e058c1801769c7f889bcd7b4fb6 424 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 23 419 1.9E-104 T 14-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 D521_0142 79620e058c1801769c7f889bcd7b4fb6 424 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 324 337 - T 14-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 D521_0142 79620e058c1801769c7f889bcd7b4fb6 424 SUPERFAMILY SSF51905 22 413 2.13E-50 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0255 c5ac894d122e3f9a77fd56065d8863ef 188 SUPERFAMILY SSF51182 7 185 5.71E-74 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily D521_0255 c5ac894d122e3f9a77fd56065d8863ef 188 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 7 179 2.0E-67 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 D521_0255 c5ac894d122e3f9a77fd56065d8863ef 188 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 9 183 4.0E-76 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 D521_0255 c5ac894d122e3f9a77fd56065d8863ef 188 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 12 181 8.8E-72 T 14-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 D521_0255 c5ac894d122e3f9a77fd56065d8863ef 188 Gene3D G3DSA:2.60.120.10 4 187 1.9E-71 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_0491 73d6d2f79718047e9a6ff92382b8cf66 371 Pfam PF03739 Predicted permease YjgP/YjgQ family 9 350 5.4E-58 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 D521_0491 73d6d2f79718047e9a6ff92382b8cf66 371 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 2 350 1.9E-110 T 14-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 D521_0758 1b13efe7a2632d0073403440d92432b3 488 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 69 121 2.3E-5 T 14-10-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0758 1b13efe7a2632d0073403440d92432b3 488 Pfam PF00361 Proton-conducting membrane transporter 129 413 2.4E-77 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0758 1b13efe7a2632d0073403440d92432b3 488 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 3 482 7.0E-185 T 14-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0758 1b13efe7a2632d0073403440d92432b3 488 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 134 153 7.1E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0758 1b13efe7a2632d0073403440d92432b3 488 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 233 257 7.1E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0758 1b13efe7a2632d0073403440d92432b3 488 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 373 399 7.1E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0758 1b13efe7a2632d0073403440d92432b3 488 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 321 340 7.1E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0758 1b13efe7a2632d0073403440d92432b3 488 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 164 188 7.1E-49 T 14-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0531 317ea15c42f8ed32011b5639e576a970 191 Pfam PF01169 Uncharacterized protein family UPF0016 111 184 4.6E-23 T 14-10-2018 IPR001727 Gdt1 family D521_0531 317ea15c42f8ed32011b5639e576a970 191 Pfam PF01169 Uncharacterized protein family UPF0016 9 83 9.7E-20 T 14-10-2018 IPR001727 Gdt1 family D521_1969 8ef4f9e4d8467f75bab8d0769454be92 462 SUPERFAMILY SSF51905 4 445 4.92E-44 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_1969 8ef4f9e4d8467f75bab8d0769454be92 462 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 82 1.2E-14 T 14-10-2018 D521_1969 8ef4f9e4d8467f75bab8d0769454be92 462 Gene3D G3DSA:3.50.50.60 3 319 2.5E-21 T 14-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily D521_0204 e79917410f556ca9f4a7e31e97ba86be 282 Pfam PF01578 Cytochrome C assembly protein 74 278 1.8E-22 T 14-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 D521_1203 f06294c24aad0829263a98ba66bd3db4 419 Gene3D G3DSA:3.40.50.2000 223 414 9.2E-32 T 14-10-2018 D521_1203 f06294c24aad0829263a98ba66bd3db4 419 SUPERFAMILY SSF53756 45 412 2.16E-52 T 14-10-2018 D521_1203 f06294c24aad0829263a98ba66bd3db4 419 Gene3D G3DSA:3.40.50.2000 42 195 8.3E-9 T 14-10-2018 D521_1203 f06294c24aad0829263a98ba66bd3db4 419 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 125 382 5.4E-18 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 D521_1285 5de2552da5673a00e91d1ccc305dd140 229 Pfam PF13505 Outer membrane protein beta-barrel domain 13 229 3.2E-8 T 14-10-2018 IPR027385 Outer membrane protein beta-barrel D521_1285 5de2552da5673a00e91d1ccc305dd140 229 SUPERFAMILY SSF56925 28 229 4.71E-7 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel D521_1408 80e0b76f6919679567446109d2de2f70 689 Gene3D G3DSA:1.20.1600.10 15 425 2.3E-29 T 14-10-2018 D521_1408 80e0b76f6919679567446109d2de2f70 689 Pfam PF02321 Outer membrane efflux protein 23 178 3.2E-8 T 14-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 D521_1408 80e0b76f6919679567446109d2de2f70 689 SUPERFAMILY SSF56954 2 392 2.09E-31 T 14-10-2018 D521_1708 41615eb1a9c5a079cd1e4a1cae8f7c11 79 Pfam PF01206 Sulfurtransferase TusA 10 77 1.6E-20 T 14-10-2018 IPR001455 TusA-like domain D521_1708 41615eb1a9c5a079cd1e4a1cae8f7c11 79 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 11 35 - T 14-10-2018 IPR001455 TusA-like domain D521_1708 41615eb1a9c5a079cd1e4a1cae8f7c11 79 Gene3D G3DSA:3.30.110.40 4 79 2.5E-27 T 14-10-2018 IPR036868 TusA-like domain superfamily D521_1708 41615eb1a9c5a079cd1e4a1cae8f7c11 79 SUPERFAMILY SSF64307 5 78 7.33E-24 T 14-10-2018 IPR036868 TusA-like domain superfamily D521_1951 e61aabfd3682f75e99079d6d40c52ae6 144 Pfam PF03610 PTS system fructose IIA component 3 111 2.7E-17 T 14-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 D521_1951 e61aabfd3682f75e99079d6d40c52ae6 144 Gene3D G3DSA:3.40.50.510 1 144 7.7E-30 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 D521_1951 e61aabfd3682f75e99079d6d40c52ae6 144 SUPERFAMILY SSF53062 1 133 2.22E-26 T 14-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 D521_1819 255afe5f2e3dd341068c4df79b31441d 159 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 158 35.716 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1819 255afe5f2e3dd341068c4df79b31441d 159 Pfam PF01967 MoaC family 15 150 4.0E-53 T 14-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1819 255afe5f2e3dd341068c4df79b31441d 159 SUPERFAMILY SSF55040 11 155 1.44E-59 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1819 255afe5f2e3dd341068c4df79b31441d 159 Gene3D G3DSA:3.30.70.640 1 159 3.4E-68 T 14-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_1819 255afe5f2e3dd341068c4df79b31441d 159 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 152 4.0E-59 T 14-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 D521_0163 635957e95a020788cd4f49f4ff1b4ef0 88 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 6 83 5.3E-20 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 D521_0163 635957e95a020788cd4f49f4ff1b4ef0 88 Hamap MF_00910 Cell division protein FtsL [ftsL]. 1 84 14.113 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 D521_0163 635957e95a020788cd4f49f4ff1b4ef0 88 Pfam PF04999 Cell division protein FtsL 2 84 7.4E-16 T 14-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 D521_1533 ff5918a4b7e13bc30d0b70f617b6b2f7 433 Gene3D G3DSA:3.40.190.10 42 318 2.6E-39 T 14-10-2018 D521_1533 ff5918a4b7e13bc30d0b70f617b6b2f7 433 SUPERFAMILY SSF53850 36 317 9.78E-42 T 14-10-2018 D521_1533 ff5918a4b7e13bc30d0b70f617b6b2f7 433 Gene3D G3DSA:3.40.190.10 116 261 2.6E-39 T 14-10-2018 D521_1533 ff5918a4b7e13bc30d0b70f617b6b2f7 433 Pfam PF16868 NMT1-like family 43 292 1.6E-21 T 14-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family D521_1137 462ddfe78a9a0956ddc4778cf4f673f9 97 SUPERFAMILY SSF54909 1 95 1.47E-17 T 14-10-2018 IPR011008 Dimeric alpha-beta barrel D521_1137 462ddfe78a9a0956ddc4778cf4f673f9 97 Gene3D G3DSA:3.30.70.100 2 95 1.7E-15 T 14-10-2018 D521_1137 462ddfe78a9a0956ddc4778cf4f673f9 97 Pfam PF07045 Domain of unknown function (DUF1330) 5 95 7.8E-14 T 14-10-2018 IPR010753 Domain of unknown function DUF1330 D521_0547 01636ad0cc5ef4f09859f431085308cd 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 14-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 D521_0547 01636ad0cc5ef4f09859f431085308cd 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 1.5E-44 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_0547 01636ad0cc5ef4f09859f431085308cd 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 14-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 D521_0547 01636ad0cc5ef4f09859f431085308cd 112 Gene3D G3DSA:3.30.70.120 1 112 7.5E-48 T 14-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal D521_0547 01636ad0cc5ef4f09859f431085308cd 112 SMART SM00938 4 105 2.8E-69 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_0547 01636ad0cc5ef4f09859f431085308cd 112 SUPERFAMILY SSF54913 1 112 1.94E-46 T 14-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta D521_0547 01636ad0cc5ef4f09859f431085308cd 112 PIRSF PIRSF039144 1 112 2.6E-56 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_0547 01636ad0cc5ef4f09859f431085308cd 112 PRINTS PR00340 P-II protein signature 83 103 2.1E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_0547 01636ad0cc5ef4f09859f431085308cd 112 PRINTS PR00340 P-II protein signature 23 41 2.1E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_0547 01636ad0cc5ef4f09859f431085308cd 112 PRINTS PR00340 P-II protein signature 2 17 2.1E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_0547 01636ad0cc5ef4f09859f431085308cd 112 PRINTS PR00340 P-II protein signature 52 75 2.1E-45 T 14-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 D521_1722 9b78fbbd750a5b0e82c58d3f7789c6ec 533 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 275 289 2.5E-29 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase D521_1722 9b78fbbd750a5b0e82c58d3f7789c6ec 533 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 373 385 2.5E-29 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase D521_1722 9b78fbbd750a5b0e82c58d3f7789c6ec 533 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 423 439 2.5E-29 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase D521_1722 9b78fbbd750a5b0e82c58d3f7789c6ec 533 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 304 314 2.5E-29 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase D521_1722 9b78fbbd750a5b0e82c58d3f7789c6ec 533 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 483 500 2.5E-29 T 14-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase D521_1722 9b78fbbd750a5b0e82c58d3f7789c6ec 533 Gene3D G3DSA:3.40.50.150 191 500 2.4E-78 T 14-10-2018 D521_1722 9b78fbbd750a5b0e82c58d3f7789c6ec 533 SUPERFAMILY SSF53335 186 501 1.48E-75 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1722 9b78fbbd750a5b0e82c58d3f7789c6ec 533 Pfam PF01189 16S rRNA methyltransferase RsmB/F 292 498 9.9E-50 T 14-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 D521_0646 b7b014d988813c4f8f11ee4c7e706b6f 286 SUPERFAMILY SSF55073 112 278 4.39E-48 T 14-10-2018 IPR029787 Nucleotide cyclase D521_0646 b7b014d988813c4f8f11ee4c7e706b6f 286 Pfam PF00990 Diguanylate cyclase, GGDEF domain 108 271 3.7E-46 T 14-10-2018 IPR000160 GGDEF domain D521_0646 b7b014d988813c4f8f11ee4c7e706b6f 286 SMART SM00267 96 276 1.4E-57 T 14-10-2018 IPR000160 GGDEF domain D521_0646 b7b014d988813c4f8f11ee4c7e706b6f 286 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 103 274 6.5E-53 T 14-10-2018 IPR000160 GGDEF domain D521_0646 b7b014d988813c4f8f11ee4c7e706b6f 286 Gene3D G3DSA:3.30.70.270 93 277 2.1E-58 T 14-10-2018 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 14-10-2018 IPR020610 Thiolase, active site GO:0016747 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 SUPERFAMILY SSF53901 272 393 3.64E-43 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 Gene3D G3DSA:3.40.47.10 128 390 1.6E-143 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 SUPERFAMILY SSF53901 4 270 3.99E-79 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 Gene3D G3DSA:3.40.47.10 7 277 1.6E-143 T 14-10-2018 IPR016039 Thiolase-like GO:0003824 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 ProSitePatterns PS00737 Thiolases signature 2. 340 356 - T 14-10-2018 IPR020613 Thiolase, conserved site GO:0016747 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 Pfam PF02803 Thiolase, C-terminal domain 272 393 1.5E-46 T 14-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 2.3E-132 T 14-10-2018 IPR002155 Thiolase GO:0016747 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 Pfam PF00108 Thiolase, N-terminal domain 5 263 7.3E-84 T 14-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 PIRSF PIRSF000429 1 394 3.1E-120 T 14-10-2018 IPR002155 Thiolase GO:0016747 D521_0923 50d9ed64e008d76d9e7d37852681b814 394 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 14-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 D521_0390 80298bee0d066673dd7b845fe81bef7a 421 Pfam PF00582 Universal stress protein family 254 391 1.0E-17 T 14-10-2018 IPR006016 UspA D521_0390 80298bee0d066673dd7b845fe81bef7a 421 Pfam PF03741 Integral membrane protein TerC family 14 183 4.6E-44 T 14-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 D521_0390 80298bee0d066673dd7b845fe81bef7a 421 PRINTS PR01438 Universal stress protein signature 352 364 1.4E-6 T 14-10-2018 IPR006015 Universal stress protein A D521_0390 80298bee0d066673dd7b845fe81bef7a 421 PRINTS PR01438 Universal stress protein signature 253 271 1.4E-6 T 14-10-2018 IPR006015 Universal stress protein A D521_0390 80298bee0d066673dd7b845fe81bef7a 421 PRINTS PR01438 Universal stress protein signature 370 392 1.4E-6 T 14-10-2018 IPR006015 Universal stress protein A D521_0390 80298bee0d066673dd7b845fe81bef7a 421 Gene3D G3DSA:3.40.50.620 251 392 2.5E-20 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_0390 80298bee0d066673dd7b845fe81bef7a 421 SUPERFAMILY SSF52402 253 392 8.37E-23 T 14-10-2018 D521_0390 80298bee0d066673dd7b845fe81bef7a 421 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 11 184 2.0E-68 T 14-10-2018 IPR022301 Integral membrane protein YjbE D521_0737 49332c991fc0d0ff988d2c5349f34a63 287 Pfam PF01066 CDP-alcohol phosphatidyltransferase 57 120 3.8E-15 T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 D521_0737 49332c991fc0d0ff988d2c5349f34a63 287 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 98 120 - T 14-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 D521_0737 49332c991fc0d0ff988d2c5349f34a63 287 Gene3D G3DSA:1.20.120.1760 51 177 1.6E-16 T 14-10-2018 D521_0737 49332c991fc0d0ff988d2c5349f34a63 287 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 64 226 3.2E-37 T 14-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 D521_0305 26538e633bf3771f59357a1ab165f9d0 179 Pfam PF04982 HPP family 59 175 3.2E-35 T 14-10-2018 IPR007065 HPP D521_1123 dead77e5a8a630149c19eb3385c1f735 91 Gene3D G3DSA:1.20.1280.290 1 91 1.1E-28 T 14-10-2018 D521_1123 dead77e5a8a630149c19eb3385c1f735 91 Pfam PF04193 PQ loop repeat 9 61 2.4E-9 T 14-10-2018 IPR006603 PQ-loop repeat D521_0539 2f07902791be1e9c07636f0aa891ef88 157 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 4 143 4.2E-22 T 14-10-2018 IPR009936 Protein of unknown function DUF1468 D521_1030 be682fedf126e8e2ac336135d8604fb7 264 Pfam PF01614 Bacterial transcriptional regulator 131 251 1.4E-31 T 14-10-2018 IPR014757 Transcription regulator IclR, C-terminal D521_1030 be682fedf126e8e2ac336135d8604fb7 264 Pfam PF09339 IclR helix-turn-helix domain 16 64 1.5E-14 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 D521_1030 be682fedf126e8e2ac336135d8604fb7 264 SUPERFAMILY SSF55781 70 255 1.7E-44 T 14-10-2018 D521_1030 be682fedf126e8e2ac336135d8604fb7 264 SMART SM00346 13 102 3.3E-22 T 14-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 D521_1030 be682fedf126e8e2ac336135d8604fb7 264 SUPERFAMILY SSF46785 13 84 1.03E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_1030 be682fedf126e8e2ac336135d8604fb7 264 Gene3D G3DSA:3.30.450.40 84 261 3.1E-53 T 14-10-2018 IPR029016 GAF-like domain superfamily D521_1030 be682fedf126e8e2ac336135d8604fb7 264 Gene3D G3DSA:1.10.10.10 11 83 4.0E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1562 2d4528191e0a3dd9ecbf086cca9389bc 158 Gene3D G3DSA:1.10.287.70 46 147 1.8E-9 T 14-10-2018 D521_1562 2d4528191e0a3dd9ecbf086cca9389bc 158 Pfam PF07885 Ion channel 72 145 2.6E-9 T 14-10-2018 IPR013099 Potassium channel domain D521_1562 2d4528191e0a3dd9ecbf086cca9389bc 158 SUPERFAMILY SSF81324 40 145 3.4E-11 T 14-10-2018 D521_1149 c5f47f3514736d9e78df10f409d6f684 326 SUPERFAMILY SSF103481 50 155 1.01E-13 T 14-10-2018 D521_1149 c5f47f3514736d9e78df10f409d6f684 326 Pfam PF00892 EamA-like transporter family 165 300 1.4E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 D521_1149 c5f47f3514736d9e78df10f409d6f684 326 Pfam PF00892 EamA-like transporter family 16 152 5.5E-14 T 14-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 D521_1149 c5f47f3514736d9e78df10f409d6f684 326 SUPERFAMILY SSF103481 224 304 1.23E-11 T 14-10-2018 D521_1175 d7b38ba4302601892a4c4a0a2b7f1d4c 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 32 297 4.4E-38 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 D521_1903 11d1d39830a7ffd073d0d2fe92d0c9a6 330 SMART SM00116 281 329 0.0067 T 14-10-2018 IPR000644 CBS domain D521_1903 11d1d39830a7ffd073d0d2fe92d0c9a6 330 SMART SM00116 216 264 46.0 T 14-10-2018 IPR000644 CBS domain D521_1903 11d1d39830a7ffd073d0d2fe92d0c9a6 330 PIRSF PIRSF004692 1 330 1.8E-125 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 D521_1903 11d1d39830a7ffd073d0d2fe92d0c9a6 330 Gene3D G3DSA:3.10.580.10 203 327 1.6E-37 T 14-10-2018 D521_1903 11d1d39830a7ffd073d0d2fe92d0c9a6 330 Pfam PF01380 SIS domain 46 178 9.2E-34 T 14-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 D521_1903 11d1d39830a7ffd073d0d2fe92d0c9a6 330 Pfam PF00571 CBS domain 207 264 5.4E-4 T 14-10-2018 IPR000644 CBS domain D521_1903 11d1d39830a7ffd073d0d2fe92d0c9a6 330 Pfam PF00571 CBS domain 279 327 4.3E-7 T 14-10-2018 IPR000644 CBS domain D521_1903 11d1d39830a7ffd073d0d2fe92d0c9a6 330 SUPERFAMILY SSF53697 8 328 9.79E-66 T 14-10-2018 D521_1903 11d1d39830a7ffd073d0d2fe92d0c9a6 330 Gene3D G3DSA:3.40.50.10490 4 202 4.6E-64 T 14-10-2018 D521_1903 11d1d39830a7ffd073d0d2fe92d0c9a6 330 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 51 320 4.4E-108 T 14-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 D521_0841 db54a1e19068fddc7874f7203d93f17a 107 PRINTS PR01727 Prokaryotic integration host factor signature 49 64 9.0E-13 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_0841 db54a1e19068fddc7874f7203d93f17a 107 PRINTS PR01727 Prokaryotic integration host factor signature 83 97 9.0E-13 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_0841 db54a1e19068fddc7874f7203d93f17a 107 PRINTS PR01727 Prokaryotic integration host factor signature 67 80 9.0E-13 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_0841 db54a1e19068fddc7874f7203d93f17a 107 Gene3D G3DSA:4.10.520.10 8 105 1.3E-33 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 D521_0841 db54a1e19068fddc7874f7203d93f17a 107 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 9 102 1.6E-38 T 14-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 D521_0841 db54a1e19068fddc7874f7203d93f17a 107 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 8 104 27.575 T 14-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 D521_0841 db54a1e19068fddc7874f7203d93f17a 107 SUPERFAMILY SSF47729 10 101 1.1E-29 T 14-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 D521_0841 db54a1e19068fddc7874f7203d93f17a 107 SMART SM00411 10 99 1.1E-36 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_0841 db54a1e19068fddc7874f7203d93f17a 107 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 55 74 - T 14-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 D521_0841 db54a1e19068fddc7874f7203d93f17a 107 Pfam PF00216 Bacterial DNA-binding protein 10 98 1.0E-28 T 14-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 D521_1190 eb445cb1dd28f0d60245f5a226bcf8ec 73 PIRSF PIRSF036704 4 72 2.6E-11 T 14-10-2018 IPR014177 Putative formate dehydrogenase, TAT signal-containing D521_0336 3789d5c83a22080df944427e481f80f8 235 Pfam PF08808 RES domain 65 206 5.5E-27 T 14-10-2018 IPR014914 RES domain D521_0336 3789d5c83a22080df944427e481f80f8 235 SMART SM00953 72 206 4.6E-27 T 14-10-2018 IPR014914 RES domain D521_1526 71c59671cb60b70acecd2195e128e87f 55 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 3 45 1.0E-7 T 14-10-2018 IPR008621 Cbb3-type cytochrome oxidase component D521_1027 c04cc4c988c8f55924ddf9fa7077cc58 245 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 40 210 9.8E-65 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 D521_1027 c04cc4c988c8f55924ddf9fa7077cc58 245 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 245 79.659 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 D521_1027 c04cc4c988c8f55924ddf9fa7077cc58 245 Gene3D G3DSA:3.40.630.70 65 241 1.5E-57 T 14-10-2018 D521_1027 c04cc4c988c8f55924ddf9fa7077cc58 245 Gene3D G3DSA:2.30.210.20 8 64 1.5E-15 T 14-10-2018 D521_1027 c04cc4c988c8f55924ddf9fa7077cc58 245 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 43 226 1.2E-49 T 14-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 D521_1027 c04cc4c988c8f55924ddf9fa7077cc58 245 SUPERFAMILY SSF55729 6 236 1.09E-76 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_1331 4adbf7fff4feea4e61dfc5ff316ca532 390 Pfam PF04295 D-galactarate dehydratase / Altronate hydrolase, C terminus 8 386 3.3E-125 T 14-10-2018 IPR007392 D-galactarate/Altronate dehydratase, C-terminal GO:0016829 D521_0791 3a758441e43b3acf8522055ec50f795f 235 Gene3D G3DSA:1.20.58.220 121 233 7.3E-31 T 14-10-2018 IPR038078 PhoU-like domain superfamily D521_0791 3a758441e43b3acf8522055ec50f795f 235 SUPERFAMILY SSF109755 8 228 6.07E-67 T 14-10-2018 D521_0791 3a758441e43b3acf8522055ec50f795f 235 Gene3D G3DSA:1.20.58.220 1 119 3.0E-37 T 14-10-2018 IPR038078 PhoU-like domain superfamily D521_0791 3a758441e43b3acf8522055ec50f795f 235 PIRSF PIRSF003107 3 224 4.3E-60 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 D521_0791 3a758441e43b3acf8522055ec50f795f 235 Pfam PF01895 PhoU domain 21 109 3.7E-18 T 14-10-2018 IPR026022 PhoU domain D521_0791 3a758441e43b3acf8522055ec50f795f 235 Pfam PF01895 PhoU domain 130 210 1.0E-16 T 14-10-2018 IPR026022 PhoU domain D521_0791 3a758441e43b3acf8522055ec50f795f 235 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 8 219 7.3E-68 T 14-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 D521_0446 773ecdfe1b2bda16c962343ff7353d1a 1140 SUPERFAMILY SSF55464 2 305 6.41E-66 T 14-10-2018 D521_0446 773ecdfe1b2bda16c962343ff7353d1a 1140 TIGRFAM TIGR02686 relax_trwC: conjugative relaxase domain 13 300 1.8E-58 T 14-10-2018 IPR014059 Conjugative relaxase, N-terminal D521_0446 773ecdfe1b2bda16c962343ff7353d1a 1140 SUPERFAMILY SSF52540 721 1099 3.32E-23 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0446 773ecdfe1b2bda16c962343ff7353d1a 1140 Gene3D G3DSA:3.40.50.300 994 1104 3.1E-11 T 14-10-2018 D521_0446 773ecdfe1b2bda16c962343ff7353d1a 1140 Pfam PF08751 TrwC relaxase 13 301 1.1E-62 T 14-10-2018 IPR014862 TrwC relaxase D521_0446 773ecdfe1b2bda16c962343ff7353d1a 1140 Pfam PF13604 AAA domain 681 790 8.9E-21 T 14-10-2018 D521_0446 773ecdfe1b2bda16c962343ff7353d1a 1140 Pfam PF13604 AAA domain 453 540 8.5E-15 T 14-10-2018 D521_0446 773ecdfe1b2bda16c962343ff7353d1a 1140 Gene3D G3DSA:3.40.50.300 420 559 1.0E-12 T 14-10-2018 D521_0446 773ecdfe1b2bda16c962343ff7353d1a 1140 Gene3D G3DSA:3.40.50.300 629 784 3.1E-13 T 14-10-2018 D521_0446 773ecdfe1b2bda16c962343ff7353d1a 1140 SUPERFAMILY SSF52540 449 748 9.04E-16 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0291 701ea5f8ee109cdb51adb832cf3c6189 401 Pfam PF02601 Exonuclease VII, large subunit 125 334 2.2E-77 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 D521_0291 701ea5f8ee109cdb51adb832cf3c6189 401 Pfam PF02601 Exonuclease VII, large subunit 315 395 6.3E-8 T 14-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 D521_0291 701ea5f8ee109cdb51adb832cf3c6189 401 Pfam PF13742 OB-fold nucleic acid binding domain 9 101 2.8E-27 T 14-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 D521_0291 701ea5f8ee109cdb51adb832cf3c6189 401 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 10 396 2.6E-137 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 D521_0291 701ea5f8ee109cdb51adb832cf3c6189 401 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 6 398 26.467 T 14-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 D521_0546 9e72315676ce5704e0776976d22f291e 345 Gene3D G3DSA:1.10.260.40 9 81 1.2E-6 T 14-10-2018 D521_0546 9e72315676ce5704e0776976d22f291e 345 SUPERFAMILY SSF47413 14 76 1.9E-5 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 D521_1954 9617cdee53815b90f52e28abb4527e52 487 ProSitePatterns PS01219 Ammonium transporters signature. 233 258 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 D521_1954 9617cdee53815b90f52e28abb4527e52 487 TIGRFAM TIGR00836 amt: ammonium transporter 57 485 5.2E-137 T 14-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 D521_1954 9617cdee53815b90f52e28abb4527e52 487 Gene3D G3DSA:1.10.3430.10 12 487 7.7E-139 T 14-10-2018 IPR029020 Ammonium/urea transporter D521_1954 9617cdee53815b90f52e28abb4527e52 487 Pfam PF00909 Ammonium Transporter Family 59 485 1.4E-122 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 D521_1954 9617cdee53815b90f52e28abb4527e52 487 SUPERFAMILY SSF111352 54 466 4.58E-128 T 14-10-2018 D521_0630 b663a4991d597a0c27fec048b26edf6a 383 SUPERFAMILY SSF55073 224 382 1.49E-49 T 14-10-2018 IPR029787 Nucleotide cyclase D521_0630 b663a4991d597a0c27fec048b26edf6a 383 Gene3D G3DSA:3.30.70.270 214 383 5.5E-58 T 14-10-2018 D521_0630 b663a4991d597a0c27fec048b26edf6a 383 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 215 379 7.4E-43 T 14-10-2018 IPR000160 GGDEF domain D521_0630 b663a4991d597a0c27fec048b26edf6a 383 SMART SM00267 208 381 1.4E-62 T 14-10-2018 IPR000160 GGDEF domain D521_0630 b663a4991d597a0c27fec048b26edf6a 383 Pfam PF00990 Diguanylate cyclase, GGDEF domain 219 374 2.4E-46 T 14-10-2018 IPR000160 GGDEF domain D521_1392 e50794d25e809fedc7de8035c76c9e8e 305 SUPERFAMILY SSF88713 15 276 7.79E-27 T 14-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 D521_1392 e50794d25e809fedc7de8035c76c9e8e 305 Gene3D G3DSA:3.20.20.370 2 290 4.8E-22 T 14-10-2018 D521_1392 e50794d25e809fedc7de8035c76c9e8e 305 Pfam PF01522 Polysaccharide deacetylase 15 170 5.3E-8 T 14-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 D521_0746 40caa69dc59bc24d2f7a05805e95553b 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 22 118 2.5E-38 T 14-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0746 40caa69dc59bc24d2f7a05805e95553b 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 2 119 20.346 T 14-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 D521_0746 40caa69dc59bc24d2f7a05805e95553b 119 Gene3D G3DSA:1.20.58.1610 2 119 1.6E-43 T 14-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0588 4d57880c3745a4ef9d6078bcba983ef1 451 Pfam PF11902 Protein of unknown function (DUF3422) 5 443 1.4E-113 T 14-10-2018 IPR021830 Protein of unknown function DUF3422 D521_1410 deaf0b2e3962b63802529b3c3ab1d02e 339 Pfam PF16363 GDP-mannose 4,6 dehydratase 7 326 8.4E-56 T 14-10-2018 IPR016040 NAD(P)-binding domain D521_1410 deaf0b2e3962b63802529b3c3ab1d02e 339 Gene3D G3DSA:3.40.50.720 6 276 6.2E-140 T 14-10-2018 D521_1410 deaf0b2e3962b63802529b3c3ab1d02e 339 Gene3D G3DSA:3.90.25.10 196 331 6.2E-140 T 14-10-2018 D521_1410 deaf0b2e3962b63802529b3c3ab1d02e 339 SUPERFAMILY SSF51735 3 332 1.99E-94 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1410 deaf0b2e3962b63802529b3c3ab1d02e 339 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 6 336 9.4E-137 T 14-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 D521_1395 7f976cb281a8b7f7090bc062e9603b92 177 Pfam PF00877 NlpC/P60 family 65 172 2.6E-29 T 14-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain D521_1395 7f976cb281a8b7f7090bc062e9603b92 177 Gene3D G3DSA:3.90.1720.10 43 175 2.2E-37 T 14-10-2018 D521_1395 7f976cb281a8b7f7090bc062e9603b92 177 SUPERFAMILY SSF54001 52 173 3.04E-37 T 14-10-2018 IPR038765 Papain-like cysteine peptidase superfamily D521_1084 3f97c95a6ac05bea77c8dee3cf382d18 264 Gene3D G3DSA:3.40.1210.10 1 262 1.8E-87 T 14-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 D521_1084 3f97c95a6ac05bea77c8dee3cf382d18 264 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 9 248 1.6E-64 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 D521_1084 3f97c95a6ac05bea77c8dee3cf382d18 264 SUPERFAMILY SSF64167 9 257 2.62E-79 T 14-10-2018 D521_1084 3f97c95a6ac05bea77c8dee3cf382d18 264 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 8 264 37.063 T 14-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 D521_1084 3f97c95a6ac05bea77c8dee3cf382d18 264 Pfam PF01975 Survival protein SurE 10 198 1.6E-57 T 14-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 D521_1864 a01552976daf42004ab9a66333edf48b 844 Pfam PF04453 Organic solvent tolerance protein 326 750 4.3E-63 T 14-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 D521_1864 a01552976daf42004ab9a66333edf48b 844 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 22 812 17.202 T 14-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 D521_0037 92d761b7ccf828bc659e505bda39397f 28 Gene3D G3DSA:2.40.30.10 1 27 2.4E-11 T 14-10-2018 D521_0037 92d761b7ccf828bc659e505bda39397f 28 SUPERFAMILY SSF50465 2 28 1.27E-7 T 14-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal D521_0037 92d761b7ccf828bc659e505bda39397f 28 Pfam PF03143 Elongation factor Tu C-terminal domain 6 26 6.6E-7 T 14-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal D521_0765 19a221f3faf8a376baf25526ff2c08eb 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 217 3.3E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 D521_0765 19a221f3faf8a376baf25526ff2c08eb 221 SUPERFAMILY SSF161098 16 203 2.35E-35 T 14-10-2018 IPR035906 MetI-like superfamily D521_0765 19a221f3faf8a376baf25526ff2c08eb 221 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 15 110 5.0E-22 T 14-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 D521_0765 19a221f3faf8a376baf25526ff2c08eb 221 Gene3D G3DSA:1.10.3720.10 8 218 7.4E-49 T 14-10-2018 IPR035906 MetI-like superfamily D521_1169 d23a27487c71e53efdb16530f0649bf6 158 SUPERFAMILY SSF55961 1 146 3.83E-38 T 14-10-2018 D521_1169 d23a27487c71e53efdb16530f0649bf6 158 Gene3D G3DSA:3.30.530.20 1 149 7.9E-41 T 14-10-2018 IPR023393 START-like domain superfamily D521_1169 d23a27487c71e53efdb16530f0649bf6 158 Pfam PF06240 Carbon monoxide dehydrogenase subunit G (CoxG) 5 145 5.0E-33 T 14-10-2018 IPR010419 Carbon monoxide dehydrogenase subunit G D521_0088 8fee713bd4c60d3ba56014d9d6d5f329 161 Pfam PF01202 Shikimate kinase 1 157 4.3E-51 T 14-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 D521_0088 8fee713bd4c60d3ba56014d9d6d5f329 161 PRINTS PR01100 Shikimate kinase family signature 47 55 1.1E-12 T 14-10-2018 D521_0088 8fee713bd4c60d3ba56014d9d6d5f329 161 PRINTS PR01100 Shikimate kinase family signature 19 32 1.1E-12 T 14-10-2018 D521_0088 8fee713bd4c60d3ba56014d9d6d5f329 161 PRINTS PR01100 Shikimate kinase family signature 86 103 1.1E-12 T 14-10-2018 D521_0088 8fee713bd4c60d3ba56014d9d6d5f329 161 PRINTS PR01100 Shikimate kinase family signature 65 74 1.1E-12 T 14-10-2018 D521_0088 8fee713bd4c60d3ba56014d9d6d5f329 161 Gene3D G3DSA:3.40.50.300 1 160 1.0E-51 T 14-10-2018 D521_0088 8fee713bd4c60d3ba56014d9d6d5f329 161 ProSitePatterns PS01128 Shikimate kinase signature. 48 73 - T 14-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 D521_0088 8fee713bd4c60d3ba56014d9d6d5f329 161 SUPERFAMILY SSF52540 1 155 1.2E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0088 8fee713bd4c60d3ba56014d9d6d5f329 161 Hamap MF_00109 Shikimate kinase [aroK]. 1 158 24.171 T 14-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 D521_1537 054d61a4ec22200e428688a9a334aecc 174 SUPERFAMILY SSF52833 31 172 1.03E-32 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1537 054d61a4ec22200e428688a9a334aecc 174 Pfam PF08534 Redoxin 36 157 6.6E-15 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 D521_1537 054d61a4ec22200e428688a9a334aecc 174 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 6 170 1.7E-53 T 14-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 D521_1537 054d61a4ec22200e428688a9a334aecc 174 Gene3D G3DSA:3.40.30.10 22 174 9.1E-41 T 14-10-2018 D521_1537 054d61a4ec22200e428688a9a334aecc 174 ProSitePatterns PS00194 Thioredoxin family active site. 65 83 - T 14-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 D521_1174 b02bd2d71fba873cea37bc2a02dcf0e4 284 Pfam PF02653 Branched-chain amino acid transport system / permease component 3 269 1.0E-38 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 D521_0262 04450bb3fce49c3faf6001d2b29233a6 164 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 21 157 19.275 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 D521_0262 04450bb3fce49c3faf6001d2b29233a6 164 Gene3D G3DSA:1.10.940.10 18 161 6.9E-37 T 14-10-2018 IPR035926 NusB-like superfamily D521_0262 04450bb3fce49c3faf6001d2b29233a6 164 Pfam PF01029 NusB family 24 152 9.4E-28 T 14-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 D521_0262 04450bb3fce49c3faf6001d2b29233a6 164 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 23 155 9.7E-33 T 14-10-2018 IPR011605 NusB antitermination factor GO:0006353 D521_0262 04450bb3fce49c3faf6001d2b29233a6 164 SUPERFAMILY SSF48013 21 157 5.63E-33 T 14-10-2018 IPR035926 NusB-like superfamily D521_0499 93bab49c2db01756ab081a3747c5cdff 119 Pfam PF05164 Cell division protein ZapA 6 94 1.0E-12 T 14-10-2018 IPR007838 Cell division protein ZapA-like D521_0499 93bab49c2db01756ab081a3747c5cdff 119 SUPERFAMILY SSF102829 5 72 6.41E-10 T 14-10-2018 IPR036192 Cell division protein ZapA-like superfamily D521_1241 330978e83406716f68c5a1d4cf9b5871 320 Gene3D G3DSA:3.40.190.150 25 310 4.6E-109 T 14-10-2018 D521_1241 330978e83406716f68c5a1d4cf9b5871 320 Gene3D G3DSA:3.40.190.10 122 245 4.6E-109 T 14-10-2018 D521_1241 330978e83406716f68c5a1d4cf9b5871 320 SUPERFAMILY SSF53850 107 283 1.27E-14 T 14-10-2018 D521_1241 330978e83406716f68c5a1d4cf9b5871 320 PIRSF PIRSF017082 1 319 1.4E-74 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_1241 330978e83406716f68c5a1d4cf9b5871 320 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 45 316 1.6E-84 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0156 d1663b14df506aa096416e59a48bd40c 240 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 10 181 1.3E-46 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 D521_0156 d1663b14df506aa096416e59a48bd40c 240 SUPERFAMILY SSF52540 8 214 3.9E-51 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0156 d1663b14df506aa096416e59a48bd40c 240 PIRSF PIRSF006755 5 236 3.1E-69 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 D521_0156 d1663b14df506aa096416e59a48bd40c 240 Gene3D G3DSA:3.40.50.300 6 227 6.5E-63 T 14-10-2018 D521_0156 d1663b14df506aa096416e59a48bd40c 240 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 6 215 28.791 T 14-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 D521_0156 d1663b14df506aa096416e59a48bd40c 240 Pfam PF13500 AAA domain 7 214 2.0E-38 T 14-10-2018 D521_1178 f3e15eaa56c21c4c88e3192523f73ba5 167 Pfam PF09335 SNARE associated Golgi protein 52 145 3.9E-11 T 14-10-2018 IPR032816 SNARE associated Golgi protein D521_1615 07699ee3652d2dbabf0f233744ae140c 138 Gene3D G3DSA:3.10.129.10 1 138 2.3E-43 T 14-10-2018 D521_1615 07699ee3652d2dbabf0f233744ae140c 138 SUPERFAMILY SSF54637 1 133 7.81E-35 T 14-10-2018 IPR029069 HotDog domain superfamily D521_1615 07699ee3652d2dbabf0f233744ae140c 138 PIRSF PIRSF014972 2 138 3.2E-44 T 14-10-2018 IPR025540 Fluoroacetyl-CoA thioesterase D521_0789 8d3b3393fb65c0b700c42f10675830b4 288 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 20 284 8.4E-84 T 14-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 D521_0789 8d3b3393fb65c0b700c42f10675830b4 288 SUPERFAMILY SSF161098 34 278 2.34E-35 T 14-10-2018 IPR035906 MetI-like superfamily D521_0789 8d3b3393fb65c0b700c42f10675830b4 288 Gene3D G3DSA:1.10.3720.10 69 286 1.0E-27 T 14-10-2018 IPR035906 MetI-like superfamily D521_0789 8d3b3393fb65c0b700c42f10675830b4 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 281 5.7E-24 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 D521_0912 70aa43e4a8f7bf7f03d131681c8cd1ab 181 Gene3D G3DSA:3.40.630.30 21 180 1.8E-31 T 14-10-2018 D521_0912 70aa43e4a8f7bf7f03d131681c8cd1ab 181 Pfam PF00583 Acetyltransferase (GNAT) family 77 148 4.3E-9 T 14-10-2018 IPR000182 GNAT domain D521_0912 70aa43e4a8f7bf7f03d131681c8cd1ab 181 SUPERFAMILY SSF55729 18 176 1.25E-24 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_2033 6226a6b6a022a22d1db5c5412a11944b 295 PIRSF PIRSF026649 2 295 1.1E-64 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 D521_2033 6226a6b6a022a22d1db5c5412a11944b 295 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 7 285 8.0E-50 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 D521_1452 6e2cb9816f2d9533c072a2e4fe652010 416 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 25 203 1.6E-55 T 14-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 D521_1452 6e2cb9816f2d9533c072a2e4fe652010 416 Gene3D G3DSA:3.30.2010.10 202 284 6.5E-31 T 14-10-2018 D521_1452 6e2cb9816f2d9533c072a2e4fe652010 416 Pfam PF01435 Peptidase family M48 207 414 7.2E-37 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 D521_2055 15d70476396a9b29d947dd1d8e6e5a15 204 Gene3D G3DSA:3.40.50.150 2 195 2.1E-26 T 14-10-2018 D521_2055 15d70476396a9b29d947dd1d8e6e5a15 204 Pfam PF08241 Methyltransferase domain 46 144 3.2E-13 T 14-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 D521_2055 15d70476396a9b29d947dd1d8e6e5a15 204 SUPERFAMILY SSF53335 3 183 4.38E-25 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1257 864c33085cbd3f9054d40a2152db39e9 257 Gene3D G3DSA:3.40.1180.10 3 243 2.7E-89 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 D521_1257 864c33085cbd3f9054d40a2152db39e9 257 SUPERFAMILY SSF64005 15 238 2.09E-84 T 14-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 D521_1257 864c33085cbd3f9054d40a2152db39e9 257 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 17 243 39.507 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 D521_1257 864c33085cbd3f9054d40a2152db39e9 257 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 17 242 2.2E-87 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 D521_1257 864c33085cbd3f9054d40a2152db39e9 257 Pfam PF01255 Putative undecaprenyl diphosphate synthase 24 242 2.1E-77 T 14-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 D521_1257 864c33085cbd3f9054d40a2152db39e9 257 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 188 205 - T 14-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 D521_2019 4134a100538e72eeebcc35542303e26b 224 Gene3D G3DSA:3.30.450.40 45 219 7.1E-23 T 14-10-2018 IPR029016 GAF-like domain superfamily D521_2019 4134a100538e72eeebcc35542303e26b 224 Pfam PF04340 Protein of unknown function, DUF484 11 216 1.9E-22 T 14-10-2018 IPR007435 Protein of unknown function DUF484 D521_0776 f634d4b951c62041990a0e0641d65e5e 469 Gene3D G3DSA:1.10.530.10 95 244 6.3E-33 T 14-10-2018 D521_0776 f634d4b951c62041990a0e0641d65e5e 469 Gene3D G3DSA:3.10.350.10 319 380 5.9E-6 T 14-10-2018 IPR036779 LysM domain superfamily D521_0776 f634d4b951c62041990a0e0641d65e5e 469 SUPERFAMILY SSF53955 99 257 2.93E-40 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily D521_0776 f634d4b951c62041990a0e0641d65e5e 469 Pfam PF01464 Transglycosylase SLT domain 109 207 8.4E-24 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 D521_0759 c19c43403dce7d95505cfb4c36887339 480 Pfam PF00361 Proton-conducting membrane transporter 120 414 3.9E-76 T 14-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_0759 c19c43403dce7d95505cfb4c36887339 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 209 230 1.7E-5 T 14-10-2018 D521_0759 c19c43403dce7d95505cfb4c36887339 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 407 426 1.7E-5 T 14-10-2018 D521_0759 c19c43403dce7d95505cfb4c36887339 480 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 66 91 1.7E-5 T 14-10-2018 D521_0759 c19c43403dce7d95505cfb4c36887339 480 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 19 466 17.369 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 D521_0759 c19c43403dce7d95505cfb4c36887339 480 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 35 464 3.0E-136 T 14-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 D521_1018 e41894b380ca2b5e3cd0fad1aa57456e 400 Gene3D G3DSA:3.90.1150.10 21 392 4.8E-133 T 14-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 D521_1018 e41894b380ca2b5e3cd0fad1aa57456e 400 SUPERFAMILY SSF53383 10 398 3.23E-97 T 14-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase D521_1018 e41894b380ca2b5e3cd0fad1aa57456e 400 Pfam PF00155 Aminotransferase class I and II 35 397 1.7E-57 T 14-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 D521_1018 e41894b380ca2b5e3cd0fad1aa57456e 400 Gene3D G3DSA:3.40.640.10 49 294 4.8E-133 T 14-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 D521_1589 0de4f247c43e2bb73f567d338df61211 88 SUPERFAMILY SSF46689 1 73 8.24E-12 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 D521_1589 0de4f247c43e2bb73f567d338df61211 88 Pfam PF01527 Transposase 2 71 1.2E-16 T 14-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 D521_1407 6889a61074944e433f1668efc9668fe9 450 Pfam PF13641 Glycosyltransferase like family 2 68 301 2.0E-16 T 14-10-2018 D521_1407 6889a61074944e433f1668efc9668fe9 450 Gene3D G3DSA:3.90.550.10 55 290 1.6E-26 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1407 6889a61074944e433f1668efc9668fe9 450 SUPERFAMILY SSF53448 65 340 3.69E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0954 4e99a929c278999cf976c7046bbf81cc 381 Pfam PF13177 DNA polymerase III, delta subunit 30 204 1.3E-38 T 14-10-2018 D521_0954 4e99a929c278999cf976c7046bbf81cc 381 SUPERFAMILY SSF52540 24 248 2.05E-38 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1170 a15d5557ead443f5230e7034348b8d81 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 52 2.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 D521_1170 a15d5557ead443f5230e7034348b8d81 236 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 59 82 2.8E-6 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 D521_1170 a15d5557ead443f5230e7034348b8d81 236 SUPERFAMILY SSF46689 25 100 2.05E-15 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 D521_1170 a15d5557ead443f5230e7034348b8d81 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 84 2.9E-10 T 14-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 D521_1170 a15d5557ead443f5230e7034348b8d81 236 Gene3D G3DSA:1.10.357.10 20 206 9.1E-20 T 14-10-2018 D521_0057 3b78e99cb2b9df5170075033c493dfac 111 ProSitePatterns PS00464 Ribosomal protein L22 signature. 85 109 - T 14-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0057 3b78e99cb2b9df5170075033c493dfac 111 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 7 108 2.2E-43 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0057 3b78e99cb2b9df5170075033c493dfac 111 SUPERFAMILY SSF54843 3 110 6.02E-41 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 D521_0057 3b78e99cb2b9df5170075033c493dfac 111 Pfam PF00237 Ribosomal protein L22p/L17e 8 109 1.1E-35 T 14-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 D521_0057 3b78e99cb2b9df5170075033c493dfac 111 Gene3D G3DSA:3.90.470.10 1 111 4.8E-43 T 14-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 D521_0057 3b78e99cb2b9df5170075033c493dfac 111 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 3 111 24.645 T 14-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1865 43d681f4da849e7e31015c1e723a9974 333 Pfam PF01636 Phosphotransferase enzyme family 28 243 3.0E-28 T 14-10-2018 IPR002575 Aminoglycoside phosphotransferase D521_1865 43d681f4da849e7e31015c1e723a9974 333 Gene3D G3DSA:3.90.1200.10 99 333 2.9E-73 T 14-10-2018 D521_1865 43d681f4da849e7e31015c1e723a9974 333 SUPERFAMILY SSF56112 6 329 1.36E-56 T 14-10-2018 IPR011009 Protein kinase-like domain superfamily D521_1865 43d681f4da849e7e31015c1e723a9974 333 Gene3D G3DSA:3.30.200.20 3 98 6.0E-19 T 14-10-2018 D521_2082 29c41e8a3043fb97fd1af9ccb2a9d295 188 Gene3D G3DSA:1.10.443.10 2 188 4.0E-35 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 D521_2082 29c41e8a3043fb97fd1af9ccb2a9d295 188 SUPERFAMILY SSF56349 3 187 1.38E-36 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_2082 29c41e8a3043fb97fd1af9ccb2a9d295 188 Pfam PF00589 Phage integrase family 5 177 6.1E-25 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 D521_1456 204512ca099d7ab88ea9b815aef21972 248 Gene3D G3DSA:3.40.1280.10 1 176 1.0E-60 T 14-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal D521_1456 204512ca099d7ab88ea9b815aef21972 248 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 232 2.2E-83 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 D521_1456 204512ca099d7ab88ea9b815aef21972 248 SUPERFAMILY SSF75217 1 235 4.58E-89 T 14-10-2018 IPR029028 Alpha/beta knot methyltransferases D521_1456 204512ca099d7ab88ea9b815aef21972 248 PIRSF PIRSF000386 1 247 3.9E-85 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 D521_1456 204512ca099d7ab88ea9b815aef21972 248 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 248 98.22 T 14-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 D521_1456 204512ca099d7ab88ea9b815aef21972 248 Gene3D G3DSA:1.10.1270.20 177 248 9.8E-30 T 14-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 D521_1456 204512ca099d7ab88ea9b815aef21972 248 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 225 1.3E-50 T 14-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 D521_0468 fd5a16529f9f0b878890203b09c5ede7 261 Pfam PF03591 AzlC protein 45 182 2.6E-22 T 14-10-2018 IPR011606 Branched-chain amino acid transport, permease D521_1183 8d7c114857a923cc7f34a9914c0371f7 243 SUPERFAMILY SSF161098 25 230 3.53E-27 T 14-10-2018 IPR035906 MetI-like superfamily D521_1183 8d7c114857a923cc7f34a9914c0371f7 243 Gene3D G3DSA:1.10.3720.10 8 239 7.0E-20 T 14-10-2018 IPR035906 MetI-like superfamily D521_0600 30f226925cce99879f8c736793d5f33a 623 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 532 2.6E-74 T 14-10-2018 IPR000914 Solute-binding protein family 5 domain D521_0600 30f226925cce99879f8c736793d5f33a 623 SUPERFAMILY SSF53850 54 618 1.17E-110 T 14-10-2018 D521_0600 30f226925cce99879f8c736793d5f33a 623 Gene3D G3DSA:3.40.190.10 32 618 6.6E-213 T 14-10-2018 D521_0600 30f226925cce99879f8c736793d5f33a 623 Gene3D G3DSA:3.10.105.10 329 595 6.6E-213 T 14-10-2018 D521_0600 30f226925cce99879f8c736793d5f33a 623 PIRSF PIRSF002741 7 619 1.7E-95 T 14-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 D521_1223 2a0a1b8b388e78c936643418aff46bc8 427 SUPERFAMILY SSF56349 80 409 3.24E-25 T 14-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 D521_1223 2a0a1b8b388e78c936643418aff46bc8 427 Gene3D G3DSA:1.10.150.130 75 192 4.9E-5 T 14-10-2018 IPR010998 Integrase/recombinase, N-terminal D521_1223 2a0a1b8b388e78c936643418aff46bc8 427 Gene3D G3DSA:1.10.443.10 197 414 8.0E-17 T 14-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 D521_1223 2a0a1b8b388e78c936643418aff46bc8 427 Pfam PF00589 Phage integrase family 232 406 4.0E-6 T 14-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 D521_1689 4e129bfc9aa325a022c73d66a2b8d878 148 SUPERFAMILY SSF89095 1 146 5.75E-43 T 14-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 D521_1689 4e129bfc9aa325a022c73d66a2b8d878 148 Pfam PF09424 Yqey-like protein 4 146 6.1E-53 T 14-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 D521_1689 4e129bfc9aa325a022c73d66a2b8d878 148 Gene3D G3DSA:1.10.1510.10 1 90 2.0E-28 T 14-10-2018 D521_1689 4e129bfc9aa325a022c73d66a2b8d878 148 Gene3D G3DSA:1.10.10.410 91 147 4.4E-18 T 14-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal D521_1915 5c53de28d15c8d0f791aa026fa1fafcb 495 SUPERFAMILY SSF89392 340 491 5.1E-20 T 14-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX D521_1915 5c53de28d15c8d0f791aa026fa1fafcb 495 Pfam PF03550 Outer membrane lipoprotein LolB 341 491 2.1E-28 T 14-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 D521_1915 5c53de28d15c8d0f791aa026fa1fafcb 495 SUPERFAMILY SSF48452 156 318 2.98E-17 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1915 5c53de28d15c8d0f791aa026fa1fafcb 495 Gene3D G3DSA:2.50.20.10 326 491 5.6E-20 T 14-10-2018 D521_1915 5c53de28d15c8d0f791aa026fa1fafcb 495 Gene3D G3DSA:1.25.40.10 148 325 2.7E-24 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 Gene3D G3DSA:3.40.1500.10 2 310 1.0E-128 T 14-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 PRINTS PR00073 Coprogen oxidase signature 170 199 5.9E-65 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 PRINTS PR00073 Coprogen oxidase signature 133 155 5.9E-65 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 PRINTS PR00073 Coprogen oxidase signature 98 122 5.9E-65 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 PRINTS PR00073 Coprogen oxidase signature 35 51 5.9E-65 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 PRINTS PR00073 Coprogen oxidase signature 242 269 5.9E-65 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 PRINTS PR00073 Coprogen oxidase signature 270 296 5.9E-65 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 SUPERFAMILY SSF102886 12 310 5.89E-131 T 14-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 Pfam PF01218 Coproporphyrinogen III oxidase 14 310 2.3E-124 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 PIRSF PIRSF000166 2 311 4.5E-122 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 8 285 52.828 T 14-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0486 5b35044c22bc20b63febeff461b73ea8 311 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 174 198 - T 14-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 D521_0903 54a12d447de06f3ebd50e7414b131f31 124 SUPERFAMILY SSF46626 4 114 1.47E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0903 54a12d447de06f3ebd50e7414b131f31 124 Gene3D G3DSA:1.10.760.10 33 114 4.4E-16 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1236 f739eb72fba12307f2ab80a7edd1a278 202 SUPERFAMILY SSF117457 3 175 1.83E-58 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 D521_1236 f739eb72fba12307f2ab80a7edd1a278 202 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 12 178 5.1E-67 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 D521_1236 f739eb72fba12307f2ab80a7edd1a278 202 Gene3D G3DSA:3.20.130.10 1 177 3.0E-66 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 D521_1236 f739eb72fba12307f2ab80a7edd1a278 202 Pfam PF05683 Fumarase C-terminus 8 177 1.6E-40 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 D521_0318 97706de59fc19ef7c974b253c9f55dcf 358 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 186 315 1.4E-19 T 14-10-2018 IPR006342 Methyltransferase FkbM D521_0318 97706de59fc19ef7c974b253c9f55dcf 358 SUPERFAMILY SSF53335 16 355 1.91E-55 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0318 97706de59fc19ef7c974b253c9f55dcf 358 Gene3D G3DSA:3.40.50.150 168 355 8.8E-38 T 14-10-2018 D521_0318 97706de59fc19ef7c974b253c9f55dcf 358 Pfam PF05050 Methyltransferase FkbM domain 188 337 8.3E-17 T 14-10-2018 IPR006342 Methyltransferase FkbM D521_0102 a9376cef23ef3dfce6659a6e33413790 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 182 201 1.2E-9 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 D521_0102 a9376cef23ef3dfce6659a6e33413790 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 202 221 1.2E-9 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 D521_0102 a9376cef23ef3dfce6659a6e33413790 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 64 86 1.2E-9 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 D521_0102 a9376cef23ef3dfce6659a6e33413790 262 Pfam PF01061 ABC-2 type transporter 18 225 6.6E-37 T 14-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 D521_0102 a9376cef23ef3dfce6659a6e33413790 262 PIRSF PIRSF006648 2 259 1.6E-23 T 14-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 D521_1120 b4ba814e1eb730e5f9bd00e9d4c4855b 257 SUPERFAMILY SSF52096 5 256 1.31E-56 T 14-10-2018 IPR029045 ClpP/crotonase-like domain superfamily D521_1120 b4ba814e1eb730e5f9bd00e9d4c4855b 257 Gene3D G3DSA:1.10.12.10 206 255 8.0E-8 T 14-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal D521_1120 b4ba814e1eb730e5f9bd00e9d4c4855b 257 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 255 6.7E-37 T 14-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 D521_1120 b4ba814e1eb730e5f9bd00e9d4c4855b 257 Gene3D G3DSA:3.90.226.10 1 202 2.7E-46 T 14-10-2018 D521_2007 660b592325aaca8b1999e7bbe805edcb 299 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 5 288 1.5E-55 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 D521_2007 660b592325aaca8b1999e7bbe805edcb 299 PIRSF PIRSF026649 4 298 4.6E-65 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 D521_0361 6c87e21da643f47ea6eb32be17cb3f1e 184 Pfam PF04205 FMN-binding domain 89 166 1.9E-9 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 D521_0361 6c87e21da643f47ea6eb32be17cb3f1e 184 SMART SM00900 89 170 3.5E-11 T 14-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 D521_1033 3991765ecb205c6ae03647cf5a0c4fda 184 TIGRFAM TIGR01841 phasin: phasin family protein 27 111 3.2E-20 T 14-10-2018 IPR010127 Phasin, subfamily 1 D521_1033 3991765ecb205c6ae03647cf5a0c4fda 184 Pfam PF09361 Phasin protein 6 104 3.5E-28 T 14-10-2018 IPR018968 Phasin D521_1324 e201405a1914602d9f410bbe09656952 150 Pfam PF02566 OsmC-like protein 38 136 8.2E-11 T 14-10-2018 IPR003718 OsmC/Ohr family D521_1324 e201405a1914602d9f410bbe09656952 150 SUPERFAMILY SSF82784 21 135 2.62E-21 T 14-10-2018 IPR036102 OsmC/Ohr superfamily D521_1324 e201405a1914602d9f410bbe09656952 150 Gene3D G3DSA:3.30.300.20 7 138 6.7E-18 T 14-10-2018 IPR015946 K homology domain-like, alpha/beta D521_2021 f9b753145f56d4e6c3e12b38d6c141dd 505 Pfam PF01425 Amidase 24 484 2.0E-148 T 14-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 D521_2021 f9b753145f56d4e6c3e12b38d6c141dd 505 ProSitePatterns PS00571 Amidases signature. 158 189 - T 14-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 D521_2021 f9b753145f56d4e6c3e12b38d6c141dd 505 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 495 91.911 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 D521_2021 f9b753145f56d4e6c3e12b38d6c141dd 505 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 494 1.3E-175 T 14-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 D521_2021 f9b753145f56d4e6c3e12b38d6c141dd 505 SUPERFAMILY SSF75304 1 499 3.14E-155 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 D521_2021 f9b753145f56d4e6c3e12b38d6c141dd 505 Gene3D G3DSA:3.90.1300.10 3 504 1.9E-191 T 14-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 D521_0505 fc6e4a66b77dfb47bac2fe7be08e00b9 205 Pfam PF00027 Cyclic nucleotide-binding domain 43 128 3.1E-7 T 14-10-2018 IPR000595 Cyclic nucleotide-binding domain D521_0505 fc6e4a66b77dfb47bac2fe7be08e00b9 205 SUPERFAMILY SSF51206 17 150 3.4E-17 T 14-10-2018 IPR018490 Cyclic nucleotide-binding-like D521_0505 fc6e4a66b77dfb47bac2fe7be08e00b9 205 Gene3D G3DSA:2.60.120.10 14 151 3.6E-15 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_1532 7f45f9b8c2e9bc282942be05c701ece4 251 Gene3D G3DSA:2.60.120.620 6 246 7.3E-84 T 14-10-2018 D521_1532 7f45f9b8c2e9bc282942be05c701ece4 251 Pfam PF10014 2OG-Fe dioxygenase 49 236 9.6E-67 T 14-10-2018 IPR018724 2OG-Fe dioxygenase D521_0366 5212fa7a76546a1734e39d6ca3bab395 327 SUPERFAMILY SSF53955 182 303 9.27E-23 T 14-10-2018 IPR023346 Lysozyme-like domain superfamily D521_0366 5212fa7a76546a1734e39d6ca3bab395 327 Gene3D G3DSA:1.10.530.10 179 306 3.5E-21 T 14-10-2018 D521_0366 5212fa7a76546a1734e39d6ca3bab395 327 Pfam PF01464 Transglycosylase SLT domain 199 291 1.6E-15 T 14-10-2018 IPR008258 Transglycosylase SLT domain 1 D521_1785 ee3a21e28769c11a67732901cf23993f 96 PRINTS PR00297 10kDa chaperonin signature 60 72 1.1E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 D521_1785 ee3a21e28769c11a67732901cf23993f 96 PRINTS PR00297 10kDa chaperonin signature 25 46 1.1E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 D521_1785 ee3a21e28769c11a67732901cf23993f 96 PRINTS PR00297 10kDa chaperonin signature 3 18 1.1E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 D521_1785 ee3a21e28769c11a67732901cf23993f 96 PRINTS PR00297 10kDa chaperonin signature 81 94 1.1E-33 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 D521_1785 ee3a21e28769c11a67732901cf23993f 96 SMART SM00883 2 94 9.3E-57 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 D521_1785 ee3a21e28769c11a67732901cf23993f 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 2.6E-34 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 D521_1785 ee3a21e28769c11a67732901cf23993f 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 14-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 D521_1785 ee3a21e28769c11a67732901cf23993f 96 SUPERFAMILY SSF50129 1 95 8.83E-34 T 14-10-2018 IPR011032 GroES-like superfamily D521_1785 ee3a21e28769c11a67732901cf23993f 96 Gene3D G3DSA:2.30.33.40 1 96 2.1E-37 T 14-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 D521_1785 ee3a21e28769c11a67732901cf23993f 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 26.075 T 14-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 D521_1553 e0180fb30f78bb72ccf9f6529e5f0322 89 TIGRFAM TIGR03643 TIGR03643: TIGR03643 family protein 14 83 9.9E-35 T 14-10-2018 IPR019882 Conserved hypothetical protein CHP03643 D521_1553 e0180fb30f78bb72ccf9f6529e5f0322 89 Pfam PF10985 Protein of unknown function (DUF2805) 15 85 8.5E-34 T 14-10-2018 IPR019882 Conserved hypothetical protein CHP03643 D521_0460 84c63ec3bfda14a662b6f830068d5f89 291 Pfam PF13730 Helix-turn-helix domain 19 68 5.4E-9 T 14-10-2018 D521_0460 84c63ec3bfda14a662b6f830068d5f89 291 Gene3D G3DSA:1.10.10.10 14 103 1.2E-6 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0048 14433de17838db7a80b9879afc456d1e 156 Gene3D G3DSA:1.10.455.10 2 155 7.5E-61 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily D521_0048 14433de17838db7a80b9879afc456d1e 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 35.705 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 D521_0048 14433de17838db7a80b9879afc456d1e 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 8.5E-67 T 14-10-2018 IPR023798 Ribosomal protein S7 domain D521_0048 14433de17838db7a80b9879afc456d1e 156 SUPERFAMILY SSF47973 2 149 7.59E-61 T 14-10-2018 IPR036823 Ribosomal protein S7 domain superfamily D521_0048 14433de17838db7a80b9879afc456d1e 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 155 2.5E-66 T 14-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 D521_0048 14433de17838db7a80b9879afc456d1e 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 14-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 D521_0048 14433de17838db7a80b9879afc456d1e 156 PIRSF PIRSF002122 3 156 2.9E-58 T 14-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 D521_0333 c168485a19e8e38686cfab2abfb56d2f 183 Pfam PF06073 Bacterial protein of unknown function (DUF934) 70 177 1.4E-29 T 14-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 D521_0333 c168485a19e8e38686cfab2abfb56d2f 183 PIRSF PIRSF030820 4 182 6.0E-35 T 14-10-2018 IPR008318 Uncharacterised conserved protein UCP030820 D521_1881 895265b8e4925ca627fba55617ac3df0 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 26.525 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 D521_1881 895265b8e4925ca627fba55617ac3df0 142 Pfam PF00572 Ribosomal protein L13 14 138 3.1E-52 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 D521_1881 895265b8e4925ca627fba55617ac3df0 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 5 141 1.2E-58 T 14-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1881 895265b8e4925ca627fba55617ac3df0 142 SUPERFAMILY SSF52161 1 139 6.02E-56 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 D521_1881 895265b8e4925ca627fba55617ac3df0 142 Gene3D G3DSA:3.90.1180.10 1 142 1.2E-56 T 14-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 D521_1881 895265b8e4925ca627fba55617ac3df0 142 PIRSF PIRSF002181 1 142 1.5E-44 T 14-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 D521_1315 35062aa2c675dec93161abd9be8efec8 130 SUPERFAMILY SSF47598 94 126 2.11E-5 T 14-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 D521_1315 35062aa2c675dec93161abd9be8efec8 130 SUPERFAMILY SSF143100 2 66 2.75E-17 T 14-10-2018 IPR035069 TTHA1013/TTHA0281-like D521_1315 35062aa2c675dec93161abd9be8efec8 130 Gene3D G3DSA:3.30.160.250 1 86 1.1E-24 T 14-10-2018 D521_1315 35062aa2c675dec93161abd9be8efec8 130 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 127 3.5E-49 T 14-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system D521_1564 4e4dfdb1cb3a191538061b0bf651f100 88 Pfam PF07369 Protein of unknown function (DUF1488) 16 80 3.1E-8 T 14-10-2018 IPR009962 Protein of unknown function DUF1488 D521_1564 4e4dfdb1cb3a191538061b0bf651f100 88 SUPERFAMILY SSF160272 13 72 1.1E-9 T 14-10-2018 IPR036692 Shew3726-like superfamily D521_0808 27417ea44d56620581485cf399d13431 258 SMART SM00563 80 191 1.3E-21 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 D521_0808 27417ea44d56620581485cf399d13431 258 Pfam PF01553 Acyltransferase 67 188 8.8E-18 T 14-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 D521_0808 27417ea44d56620581485cf399d13431 258 SUPERFAMILY SSF69593 21 257 6.93E-24 T 14-10-2018 D521_0283 564057a63038280240801645e6259e9e 105 Pfam PF01381 Helix-turn-helix 50 94 1.4E-7 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 D521_0283 564057a63038280240801645e6259e9e 105 SMART SM00530 49 103 2.7E-5 T 14-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 D521_0283 564057a63038280240801645e6259e9e 105 Gene3D G3DSA:1.10.260.40 3 103 4.7E-18 T 14-10-2018 D521_0283 564057a63038280240801645e6259e9e 105 SUPERFAMILY SSF47413 48 103 1.02E-10 T 14-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 D521_0356 234ed9175c2879bad1dc62c4fba7b346 290 SMART SM00849 19 208 4.6E-21 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0356 234ed9175c2879bad1dc62c4fba7b346 290 Gene3D G3DSA:3.60.15.10 4 290 1.3E-107 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_0356 234ed9175c2879bad1dc62c4fba7b346 290 Pfam PF00753 Metallo-beta-lactamase superfamily 23 199 3.7E-17 T 14-10-2018 IPR001279 Metallo-beta-lactamase D521_0356 234ed9175c2879bad1dc62c4fba7b346 290 SUPERFAMILY SSF56281 14 255 1.57E-48 T 14-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like D521_0279 6cd9a647b1536666318c0448a9c5e368 139 Gene3D G3DSA:3.30.420.270 60 134 4.0E-12 T 14-10-2018 D521_0279 6cd9a647b1536666318c0448a9c5e368 139 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 137 5.6E-25 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 D521_1660 d07bd05cb47e6a73d2cc916e39297b87 271 Pfam PF00127 Copper binding proteins, plastocyanin/azurin family 147 251 5.2E-11 T 14-10-2018 IPR000923 Blue (type 1) copper domain GO:0005507|GO:0009055 D521_1660 d07bd05cb47e6a73d2cc916e39297b87 271 Gene3D G3DSA:2.60.40.420 131 252 8.6E-30 T 14-10-2018 IPR008972 Cupredoxin D521_1660 d07bd05cb47e6a73d2cc916e39297b87 271 SUPERFAMILY SSF49503 141 251 7.87E-33 T 14-10-2018 IPR008972 Cupredoxin D521_0200 146482cd339650de6228eb77117776dd 189 Pfam PF08750 CNP1-like family 40 170 2.3E-38 T 14-10-2018 IPR014861 Uncharacterised domain CNP1 D521_1350 22b2cb29d0163120592576120a4ba36b 128 SUPERFAMILY SSF82649 1 125 2.12E-48 T 14-10-2018 D521_1350 22b2cb29d0163120592576120a4ba36b 128 Gene3D G3DSA:3.90.1010.10 1 128 5.5E-58 T 14-10-2018 D521_1350 22b2cb29d0163120592576120a4ba36b 128 TIGRFAM TIGR01999 iscU: FeS cluster assembly scaffold IscU 3 125 3.4E-69 T 14-10-2018 IPR011339 ISC system FeS cluster assembly, IscU scaffold GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 D521_1350 22b2cb29d0163120592576120a4ba36b 128 Pfam PF01592 NifU-like N terminal domain 2 125 4.0E-56 T 14-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 D521_0978 b86a774ef1598e9ff8c41a260a708466 141 Pfam PF02635 DsrE/DsrF-like family 45 140 1.4E-11 T 14-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein D521_0978 b86a774ef1598e9ff8c41a260a708466 141 SUPERFAMILY SSF75169 27 140 8.44E-18 T 14-10-2018 IPR027396 DsrEFH-like D521_0978 b86a774ef1598e9ff8c41a260a708466 141 Gene3D G3DSA:3.40.1260.10 24 141 5.1E-24 T 14-10-2018 IPR027396 DsrEFH-like D521_0233 80b544a4d822437a19a3a17216f3ef97 167 SUPERFAMILY SSF46785 26 157 1.36E-36 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0233 80b544a4d822437a19a3a17216f3ef97 167 Gene3D G3DSA:3.30.1490.190 109 165 5.4E-22 T 14-10-2018 D521_0233 80b544a4d822437a19a3a17216f3ef97 167 Pfam PF01475 Ferric uptake regulator family 31 153 1.5E-40 T 14-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 D521_0233 80b544a4d822437a19a3a17216f3ef97 167 Gene3D G3DSA:1.10.10.10 21 107 1.8E-25 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_1996 e4654ab47aa5f1a0935782248fd311a1 131 Pfam PF02152 Dihydroneopterin aldolase 16 125 2.3E-21 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 D521_1996 e4654ab47aa5f1a0935782248fd311a1 131 SMART SM00905 16 127 1.7E-26 T 14-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 D521_1996 e4654ab47aa5f1a0935782248fd311a1 131 Gene3D G3DSA:3.30.1130.10 1 131 3.1E-46 T 14-10-2018 D521_1996 e4654ab47aa5f1a0935782248fd311a1 131 SUPERFAMILY SSF55620 12 127 5.0E-26 T 14-10-2018 D521_1654 1300794129903767939d617423e50ac0 166 Gene3D G3DSA:3.10.310.50 14 162 1.1E-47 T 14-10-2018 D521_1654 1300794129903767939d617423e50ac0 166 Pfam PF04536 TPM domain 19 142 4.4E-14 T 14-10-2018 IPR007621 TPM domain D521_0430 c0b08faa07d70824f3836fbf1f3aaaa3 196 PIRSF PIRSF000232 5 195 6.8E-50 T 14-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like D521_0430 c0b08faa07d70824f3836fbf1f3aaaa3 196 Gene3D G3DSA:3.40.109.10 11 174 8.7E-31 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 D521_0430 c0b08faa07d70824f3836fbf1f3aaaa3 196 SUPERFAMILY SSF55469 13 194 3.4E-28 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 D521_0430 c0b08faa07d70824f3836fbf1f3aaaa3 196 Pfam PF00881 Nitroreductase family 28 173 3.1E-21 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 D521_1630 a37974bc4cebcb895df1cce2aae23a5c 382 Gene3D G3DSA:3.60.60.10 26 379 1.5E-77 T 14-10-2018 D521_1630 a37974bc4cebcb895df1cce2aae23a5c 382 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 26 347 1.9E-38 T 14-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal D521_1630 a37974bc4cebcb895df1cce2aae23a5c 382 SUPERFAMILY SSF56235 26 367 6.79E-65 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_1847 1b12e1af661b6376ae49b4ffab9e77d8 400 ProSitePatterns PS01219 Ammonium transporters signature. 156 181 - T 14-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 D521_1847 1b12e1af661b6376ae49b4ffab9e77d8 400 SUPERFAMILY SSF111352 7 374 2.35E-96 T 14-10-2018 D521_1847 1b12e1af661b6376ae49b4ffab9e77d8 400 Pfam PF00909 Ammonium Transporter Family 12 389 8.8E-91 T 14-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 D521_1847 1b12e1af661b6376ae49b4ffab9e77d8 400 Gene3D G3DSA:1.10.3430.10 1 398 3.8E-101 T 14-10-2018 IPR029020 Ammonium/urea transporter D521_1957 20f1d3f8f6cd68989a5f9086b874934a 84 Pfam PF04380 Membrane fusogenic activity 12 83 1.3E-32 T 14-10-2018 IPR007475 Membrane fusogenic activity D521_0788 64350f3a5a08f52f8a73f7ce37650806 329 Gene3D G3DSA:1.10.3720.10 82 324 2.0E-30 T 14-10-2018 IPR035906 MetI-like superfamily D521_0788 64350f3a5a08f52f8a73f7ce37650806 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 109 316 5.7E-16 T 14-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 D521_0788 64350f3a5a08f52f8a73f7ce37650806 329 SUPERFAMILY SSF161098 35 314 2.24E-33 T 14-10-2018 IPR035906 MetI-like superfamily D521_0788 64350f3a5a08f52f8a73f7ce37650806 329 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 28 321 5.1E-91 T 14-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 D521_0557 0e809dae3ee152536a53aac9b3dbc23f 128 Pfam PF02325 YGGT family 57 124 9.9E-14 T 14-10-2018 IPR003425 CCB3/YggT GO:0016020 D521_1114 064a02c28cec282f79716c5a5565483b 463 PIRSF PIRSF006603 9 458 5.2E-54 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 D521_1114 064a02c28cec282f79716c5a5565483b 463 TIGRFAM TIGR00797 matE: MATE efflux family protein 22 412 7.0E-68 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 D521_1114 064a02c28cec282f79716c5a5565483b 463 Pfam PF01554 MatE 248 408 1.6E-28 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 D521_1114 064a02c28cec282f79716c5a5565483b 463 Pfam PF01554 MatE 22 180 1.3E-24 T 14-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 D521_1298 a155ca39bf313eaca74cded6864fd494 306 Pfam PF04471 Restriction endonuclease 164 278 5.2E-25 T 14-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 D521_1298 a155ca39bf313eaca74cded6864fd494 306 Pfam PF14338 Mrr N-terminal domain 18 95 7.8E-10 T 14-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain D521_1298 a155ca39bf313eaca74cded6864fd494 306 SUPERFAMILY SSF52980 168 282 9.38E-13 T 14-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 D521_1009 06a058ed5bf5965855b5eff00e40ab07 234 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 145 156 - T 14-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site D521_1009 06a058ed5bf5965855b5eff00e40ab07 234 SUPERFAMILY SSF54292 5 103 5.41E-28 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 D521_1009 06a058ed5bf5965855b5eff00e40ab07 234 Gene3D G3DSA:1.10.1060.10 104 234 2.5E-55 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_1009 06a058ed5bf5965855b5eff00e40ab07 234 Gene3D G3DSA:3.10.20.30 1 103 1.6E-33 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_1009 06a058ed5bf5965855b5eff00e40ab07 234 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 108 1.0E-29 T 14-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1009 06a058ed5bf5965855b5eff00e40ab07 234 SUPERFAMILY SSF46548 104 231 9.24E-38 T 14-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 D521_1009 06a058ed5bf5965855b5eff00e40ab07 234 Pfam PF13534 4Fe-4S dicluster domain 144 217 9.9E-10 T 14-10-2018 D521_1009 06a058ed5bf5965855b5eff00e40ab07 234 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 9 226 5.4E-82 T 14-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 D521_1286 f9b9c9b8d5155e6b50c40b322e384cb0 140 Gene3D G3DSA:3.30.1450.10 39 139 1.0E-5 T 14-10-2018 IPR037873 BamE-like D521_1286 f9b9c9b8d5155e6b50c40b322e384cb0 140 Pfam PF04355 SmpA / OmlA family 50 132 2.1E-6 T 14-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 D521_0900 0b49c69838c1230636436ebbd8b43e1b 152 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 8 152 2.0E-26 T 14-10-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like D521_0900 0b49c69838c1230636436ebbd8b43e1b 152 Gene3D G3DSA:3.30.1330.40 1 152 4.3E-57 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 D521_0900 0b49c69838c1230636436ebbd8b43e1b 152 SUPERFAMILY SSF55298 4 152 2.2E-51 T 14-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 D521_0812 555599df15eaea1b6686bc8404bd2804 172 Pfam PF02417 Chromate transporter 3 164 1.1E-27 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 D521_0431 b05f3fba1fae1dccac4ef5bf4d182dfc 182 Pfam PF04982 HPP family 61 174 1.3E-13 T 14-10-2018 IPR007065 HPP D521_0966 016368b071d309813e27670da98f60d0 390 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 13 384 1.7E-149 T 14-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition D521_0966 016368b071d309813e27670da98f60d0 390 SUPERFAMILY SSF55729 185 356 1.52E-31 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_0966 016368b071d309813e27670da98f60d0 390 Gene3D G3DSA:3.40.630.30 184 339 1.4E-5 T 14-10-2018 D521_1814 4858c45f8991e98a0a2589d2ecd2df50 63 Pfam PF10276 Zinc-finger domain 28 52 1.8E-9 T 14-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 D521_1814 4858c45f8991e98a0a2589d2ecd2df50 63 Gene3D G3DSA:2.60.260.40 1 54 1.0E-11 T 14-10-2018 D521_2039 54accd9415ac6112f892c24c09ce2c0a 76 Pfam PF11391 Protein of unknown function (DUF2798) 13 69 3.6E-17 T 14-10-2018 IPR021529 Protein of unknown function DUF2798 D521_0895 919c6f993ad1d91fc3d7e038b27b59a4 406 Gene3D G3DSA:3.30.1540.10 242 333 2.0E-141 T 14-10-2018 D521_0895 919c6f993ad1d91fc3d7e038b27b59a4 406 SUPERFAMILY SSF89796 1 406 7.85E-142 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_0895 919c6f993ad1d91fc3d7e038b27b59a4 406 Gene3D G3DSA:3.40.50.10540 4 400 2.0E-141 T 14-10-2018 IPR023606 CoA-transferase family III domain superfamily D521_0895 919c6f993ad1d91fc3d7e038b27b59a4 406 Pfam PF02515 CoA-transferase family III 4 382 3.2E-129 T 14-10-2018 IPR003673 CoA-transferase family III GO:0003824 D521_1232 95413808089c22938b5120e799435ea7 293 SUPERFAMILY SSF56235 2 240 4.08E-31 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_1232 95413808089c22938b5120e799435ea7 293 Gene3D G3DSA:3.60.20.10 2 230 1.5E-21 T 14-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal D521_1232 95413808089c22938b5120e799435ea7 293 PIRSF PIRSF009120 1 250 2.4E-108 T 14-10-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 D521_1369 e70e1ff4bdc1843c06433df4a47a7463 156 SUPERFAMILY SSF48452 38 128 1.14E-9 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1369 e70e1ff4bdc1843c06433df4a47a7463 156 Gene3D G3DSA:1.25.40.10 24 153 3.5E-10 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1369 e70e1ff4bdc1843c06433df4a47a7463 156 Pfam PF13432 Tetratricopeptide repeat 90 126 9.2E-6 T 14-10-2018 D521_1332 a0e4dd0a79770560fe6ca6315959c04b 93 Gene3D G3DSA:3.90.1210.30 3 92 1.1E-21 T 14-10-2018 D521_1332 a0e4dd0a79770560fe6ca6315959c04b 93 SMART SM00858 12 89 3.7E-5 T 14-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 D521_0494 58a3ccccf9e221ee52699de8fd65eadb 265 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 261 19.903 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 D521_0494 58a3ccccf9e221ee52699de8fd65eadb 265 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 255 4.1E-78 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 D521_0494 58a3ccccf9e221ee52699de8fd65eadb 265 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 4 260 2.4E-77 T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 D521_0494 58a3ccccf9e221ee52699de8fd65eadb 265 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 141 153 - T 14-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 D521_0346 6d745f8dad6c0bb2bf73f37494997b5a 175 Gene3D G3DSA:1.10.60.30 108 174 5.7E-26 T 14-10-2018 D521_0346 6d745f8dad6c0bb2bf73f37494997b5a 175 PIRSF PIRSF016183 1 175 1.2E-56 T 14-10-2018 IPR006839 Ribosome-associated, YjgA D521_0346 6d745f8dad6c0bb2bf73f37494997b5a 175 Gene3D G3DSA:1.10.60.30 28 106 8.5E-20 T 14-10-2018 D521_0346 6d745f8dad6c0bb2bf73f37494997b5a 175 SUPERFAMILY SSF158710 28 173 3.14E-46 T 14-10-2018 IPR023153 PSPTO4464-like domain superfamily D521_0346 6d745f8dad6c0bb2bf73f37494997b5a 175 Pfam PF04751 Protein of unknown function (DUF615) 18 171 1.2E-49 T 14-10-2018 IPR006839 Ribosome-associated, YjgA D521_2104 5f8c0922188eb4d804191abd954c99b3 226 Gene3D G3DSA:3.40.50.2300 1 134 2.0E-35 T 14-10-2018 D521_2104 5f8c0922188eb4d804191abd954c99b3 226 Gene3D G3DSA:1.10.10.60 166 220 9.3E-10 T 14-10-2018 D521_2104 5f8c0922188eb4d804191abd954c99b3 226 SUPERFAMILY SSF46689 157 218 1.88E-11 T 14-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 D521_2104 5f8c0922188eb4d804191abd954c99b3 226 SMART SM00448 2 114 6.7E-32 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_2104 5f8c0922188eb4d804191abd954c99b3 226 Pfam PF00072 Response regulator receiver domain 4 114 7.5E-28 T 14-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 D521_2104 5f8c0922188eb4d804191abd954c99b3 226 SUPERFAMILY SSF52172 1 122 4.55E-37 T 14-10-2018 IPR011006 CheY-like superfamily D521_0704 2df94a7de9796266bde9aedf694b0e3e 106 ProSitePatterns PS01117 MarR-type HTH domain signature. 56 90 - T 14-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site D521_0704 2df94a7de9796266bde9aedf694b0e3e 106 Gene3D G3DSA:1.10.10.10 1 104 6.3E-10 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0704 2df94a7de9796266bde9aedf694b0e3e 106 SUPERFAMILY SSF46785 17 101 3.37E-10 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0498 2fb667966538f9dc098fd1d5d1c9a11e 272 Pfam PF01925 Sulfite exporter TauE/SafE 10 262 1.0E-48 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 D521_0243 9272bd19a224293db820e298f1981182 279 Pfam PF00149 Calcineurin-like phosphoesterase 3 131 3.6E-12 T 14-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 D521_0243 9272bd19a224293db820e298f1981182 279 SUPERFAMILY SSF56300 3 277 2.93E-55 T 14-10-2018 D521_0243 9272bd19a224293db820e298f1981182 279 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 4 253 3.6E-80 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 D521_0243 9272bd19a224293db820e298f1981182 279 Gene3D G3DSA:3.60.21.10 2 268 5.6E-77 T 14-10-2018 IPR029052 Metallo-dependent phosphatase-like D521_0243 9272bd19a224293db820e298f1981182 279 PIRSF PIRSF000903 2 270 1.9E-100 T 14-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 D521_1047 286285f3b9beb387aa4a435f80530a77 325 Pfam PF04116 Fatty acid hydroxylase superfamily 141 284 2.1E-28 T 14-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 D521_1480 7f0b64782cbb49199f0a644fb67272d6 293 Gene3D G3DSA:1.10.3660.10 183 291 3.3E-34 T 14-10-2018 D521_1480 7f0b64782cbb49199f0a644fb67272d6 293 SUPERFAMILY SSF51735 13 178 3.22E-45 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1480 7f0b64782cbb49199f0a644fb67272d6 293 SUPERFAMILY SSF48179 184 290 1.59E-31 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_1480 7f0b64782cbb49199f0a644fb67272d6 293 Gene3D G3DSA:3.40.50.720 9 179 2.2E-51 T 14-10-2018 D521_1480 7f0b64782cbb49199f0a644fb67272d6 293 Pfam PF02153 Prephenate dehydrogenase 25 281 7.3E-66 T 14-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 D521_0918 9aefe2e42828b9c8b237ea25112f326e 259 Gene3D G3DSA:3.60.140.10 2 259 3.2E-84 T 14-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily D521_0918 9aefe2e42828b9c8b237ea25112f326e 259 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 23 254 7.4E-73 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase D521_0918 9aefe2e42828b9c8b237ea25112f326e 259 SUPERFAMILY SSF64438 5 256 3.3E-76 T 14-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic D521_0918 9aefe2e42828b9c8b237ea25112f326e 259 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 28 255 1.9E-56 T 14-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase D521_0502 5a72f88f2e3ed2e2850b9d4d13944c20 325 Gene3D G3DSA:1.10.3470.10 4 322 7.9E-77 T 14-10-2018 IPR037294 ABC transporter, BtuC-like D521_0502 5a72f88f2e3ed2e2850b9d4d13944c20 325 SUPERFAMILY SSF81345 5 318 6.67E-67 T 14-10-2018 IPR037294 ABC transporter, BtuC-like D521_0502 5a72f88f2e3ed2e2850b9d4d13944c20 325 Pfam PF01032 FecCD transport family 14 318 6.4E-74 T 14-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 D521_1291 e63b1d8c896f01ad9060df2767ac32d7 152 Pfam PF08837 Protein of unknown function (DUF1810) 12 144 5.6E-45 T 14-10-2018 IPR014937 Protein of unknown function DUF1810 D521_1291 e63b1d8c896f01ad9060df2767ac32d7 152 SUPERFAMILY SSF140736 11 144 1.96E-44 T 14-10-2018 IPR036287 Rv1873-like superfamily D521_1291 e63b1d8c896f01ad9060df2767ac32d7 152 Gene3D G3DSA:1.25.40.380 5 147 9.3E-46 T 14-10-2018 IPR036287 Rv1873-like superfamily D521_1380 168b21ea415995ce2545f28556b7b0a1 152 SUPERFAMILY SSF54690 5 151 2.62E-52 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 D521_1380 168b21ea415995ce2545f28556b7b0a1 152 Pfam PF02391 MoaE protein 8 121 5.1E-38 T 14-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 D521_1380 168b21ea415995ce2545f28556b7b0a1 152 Gene3D G3DSA:3.90.1170.40 1 151 4.6E-52 T 14-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 D521_0943 2c830c38e16d282ac787bb2167e67a3d 108 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 33.782 T 14-10-2018 IPR023081 Cell division protein FtsB D521_0943 2c830c38e16d282ac787bb2167e67a3d 108 Pfam PF04977 Septum formation initiator 11 88 6.5E-22 T 14-10-2018 IPR007060 Septum formation initiator FtsL/DivIC D521_1737 1d205f14ce520f435db993459f56530b 74 Gene3D G3DSA:3.30.70.2340 1 69 1.1E-18 T 14-10-2018 D521_1737 1d205f14ce520f435db993459f56530b 74 Pfam PF12112 Protein of unknown function (DUF3579) 1 62 2.8E-19 T 14-10-2018 IPR021969 Protein of unknown function DUF3579 D521_1389 4d4a0f4330c7770f84885dbf9e7cf4bd 323 Gene3D G3DSA:3.90.550.10 4 207 1.2E-33 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1389 4d4a0f4330c7770f84885dbf9e7cf4bd 323 Pfam PF00535 Glycosyl transferase family 2 15 175 7.6E-25 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 D521_1389 4d4a0f4330c7770f84885dbf9e7cf4bd 323 SUPERFAMILY SSF53448 11 267 1.59E-32 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1659 6a437690d5a4722862736716e5e6d4bf 155 Pfam PF04214 Protein of unknown function, DUF 64 125 2.7E-30 T 14-10-2018 IPR007332 Protein of unknown function DUF411 D521_1659 6a437690d5a4722862736716e5e6d4bf 155 SUPERFAMILY SSF52833 25 106 7.57E-6 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0650 6b0f6267351899df31cbc01955a4e46b 517 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 300 455 3.3E-14 T 14-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 D521_0650 6b0f6267351899df31cbc01955a4e46b 517 Gene3D G3DSA:1.10.1660.10 1 114 6.2E-6 T 14-10-2018 D521_0650 6b0f6267351899df31cbc01955a4e46b 517 Gene3D G3DSA:3.30.70.1230 297 483 1.4E-28 T 14-10-2018 IPR029787 Nucleotide cyclase D521_0650 6b0f6267351899df31cbc01955a4e46b 517 SUPERFAMILY SSF55073 299 454 6.28E-29 T 14-10-2018 IPR029787 Nucleotide cyclase D521_1523 3f061af84e88bf133ae77daab3fa5d80 69 Pfam PF05751 FixH 14 45 9.8E-5 T 14-10-2018 IPR008620 Nitrogen fixation protein FixH D521_0913 26c95f8e26c3af1271c439678a7c7a91 186 Gene3D G3DSA:3.40.470.10 62 186 3.4E-6 T 14-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 D521_0913 26c95f8e26c3af1271c439678a7c7a91 186 Pfam PF03603 DNA polymerase III psi subunit 4 175 1.8E-4 T 14-10-2018 IPR004615 DNA polymerase III, psi subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 D521_0304 81bf661f273b60d7fa139bead6dfe84e 102 Gene3D G3DSA:4.10.490.10 27 102 4.8E-26 T 14-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 D521_0304 81bf661f273b60d7fa139bead6dfe84e 102 Pfam PF01355 High potential iron-sulfur protein 34 99 5.3E-26 T 14-10-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 D521_0304 81bf661f273b60d7fa139bead6dfe84e 102 SUPERFAMILY SSF57652 22 102 2.4E-27 T 14-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 D521_0370 00d50ef28d1962231d1a4917df29096d 745 TIGRFAM TIGR00178 monomer_idh: isocitrate dehydrogenase, NADP-dependent 1 741 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 D521_0370 00d50ef28d1962231d1a4917df29096d 745 PIRSF PIRSF009407 1 743 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 D521_0370 00d50ef28d1962231d1a4917df29096d 745 SUPERFAMILY SSF53659 5 741 0.0 T 14-10-2018 D521_0370 00d50ef28d1962231d1a4917df29096d 745 Gene3D G3DSA:3.40.718.10 400 662 1.3E-6 T 14-10-2018 D521_0370 00d50ef28d1962231d1a4917df29096d 745 Pfam PF03971 Monomeric isocitrate dehydrogenase 7 739 0.0 T 14-10-2018 IPR004436 Isocitrate dehydrogenase NADP-dependent, monomeric GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 D521_0804 e50b9579b70b02a7ea235151bcd59be2 312 SUPERFAMILY SSF55729 78 285 7.39E-45 T 14-10-2018 IPR016181 Acyl-CoA N-acyltransferase D521_0804 e50b9579b70b02a7ea235151bcd59be2 312 Pfam PF13444 Acetyltransferase (GNAT) domain 95 195 8.8E-36 T 14-10-2018 D521_0804 e50b9579b70b02a7ea235151bcd59be2 312 Gene3D G3DSA:3.40.630.30 80 223 6.3E-30 T 14-10-2018 D521_0832 115a7450e4f740c4d3356cb103225e75 216 Gene3D G3DSA:3.40.1080.10 2 214 2.8E-99 T 14-10-2018 D521_0832 115a7450e4f740c4d3356cb103225e75 216 ProSitePatterns PS01274 Coenzyme A transferases signature 2. 44 52 - T 14-10-2018 IPR004164 Coenzyme A transferase active site GO:0008410 Reactome: R-HSA-77108 D521_0832 115a7450e4f740c4d3356cb103225e75 216 TIGRFAM TIGR02428 pcaJ_scoB_fam: 3-oxoacid CoA-transferase, B subunit 3 211 6.4E-97 T 14-10-2018 IPR012791 3-oxoacid CoA-transferase, subunit B GO:0008410 Reactome: R-HSA-77108 D521_0832 115a7450e4f740c4d3356cb103225e75 216 SMART SM00882 6 206 3.0E-78 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 D521_0832 115a7450e4f740c4d3356cb103225e75 216 Pfam PF01144 Coenzyme A transferase 7 204 8.3E-41 T 14-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 D521_0832 115a7450e4f740c4d3356cb103225e75 216 SUPERFAMILY SSF100950 3 212 2.72E-72 T 14-10-2018 IPR037171 NagB/RpiA transferase-like D521_1363 ae519bd2464ff1c2e22ca1518e88c472 146 Pfam PF01230 HIT domain 17 102 5.9E-18 T 14-10-2018 IPR001310 Histidine triad (HIT) protein D521_1363 ae519bd2464ff1c2e22ca1518e88c472 146 PIRSF PIRSF000714 5 144 3.4E-41 T 14-10-2018 IPR026026 Histidine triad hydrolase, Hint-type D521_1363 ae519bd2464ff1c2e22ca1518e88c472 146 SUPERFAMILY SSF54197 1 135 1.7E-41 T 14-10-2018 IPR036265 HIT-like superfamily D521_1363 ae519bd2464ff1c2e22ca1518e88c472 146 Gene3D G3DSA:3.30.428.10 8 144 1.4E-41 T 14-10-2018 IPR036265 HIT-like superfamily D521_0745 44764536328d070eaab809ccfd522b91 115 PRINTS PR01651 Protein-export SecG membrane protein signature 6 26 7.0E-32 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 D521_0745 44764536328d070eaab809ccfd522b91 115 PRINTS PR01651 Protein-export SecG membrane protein signature 57 79 7.0E-32 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 D521_0745 44764536328d070eaab809ccfd522b91 115 PRINTS PR01651 Protein-export SecG membrane protein signature 26 40 7.0E-32 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 D521_0745 44764536328d070eaab809ccfd522b91 115 PRINTS PR01651 Protein-export SecG membrane protein signature 41 57 7.0E-32 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 D521_0745 44764536328d070eaab809ccfd522b91 115 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 6 76 1.0E-24 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 D521_0745 44764536328d070eaab809ccfd522b91 115 Pfam PF03840 Preprotein translocase SecG subunit 7 75 1.2E-21 T 14-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 D521_0622 2f68647bd40fb5e9cbfc7d9c99a3b118 239 Pfam PF03358 NADPH-dependent FMN reductase 34 176 6.0E-24 T 14-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 D521_0622 2f68647bd40fb5e9cbfc7d9c99a3b118 239 SUPERFAMILY SSF52218 23 226 4.66E-59 T 14-10-2018 IPR029039 Flavoprotein-like superfamily D521_0622 2f68647bd40fb5e9cbfc7d9c99a3b118 239 TIGRFAM TIGR02690 resist_ArsH: arsenical resistance protein ArsH 8 225 2.0E-119 T 14-10-2018 IPR014063 Arsenate resistance ArsH D521_0622 2f68647bd40fb5e9cbfc7d9c99a3b118 239 Gene3D G3DSA:3.40.50.360 2 239 1.1E-71 T 14-10-2018 IPR029039 Flavoprotein-like superfamily D521_1160 e6ca60f97e253a66833bcf71d80daed4 161 SUPERFAMILY SSF47240 7 127 2.29E-29 T 14-10-2018 IPR009078 Ferritin-like superfamily D521_1160 e6ca60f97e253a66833bcf71d80daed4 161 Gene3D G3DSA:1.20.1260.10 4 130 2.3E-32 T 14-10-2018 IPR012347 Ferritin-like D521_1160 e6ca60f97e253a66833bcf71d80daed4 161 Pfam PF02915 Rubrerythrin 11 126 1.3E-12 T 14-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 D521_0537 afce2621508e10e41f98986b8092a596 158 Pfam PF08909 Domain of unknown function (DUF1854) 28 157 2.6E-47 T 14-10-2018 IPR015005 Domain of unknown function DUF1854 D521_0373 03f78f8e0ae600abd93bcbdfec952cab 195 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 1 191 20.745 T 14-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 D521_0373 03f78f8e0ae600abd93bcbdfec952cab 195 Pfam PF01794 Ferric reductase like transmembrane component 37 150 7.0E-17 T 14-10-2018 IPR013130 Ferric reductase transmembrane component-like domain D521_2094 e4f417c482cd7c6cf6e2b81e81916c64 184 Pfam PF02082 Transcriptional regulator 6 87 7.8E-19 T 14-10-2018 IPR000944 Transcription regulator Rrf2-type D521_2094 e4f417c482cd7c6cf6e2b81e81916c64 184 Gene3D G3DSA:1.10.10.10 4 157 6.6E-22 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_2094 e4f417c482cd7c6cf6e2b81e81916c64 184 SUPERFAMILY SSF46785 7 122 1.16E-17 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_2094 e4f417c482cd7c6cf6e2b81e81916c64 184 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 55 73 - T 14-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site D521_0817 934f374af71505a9500f2959158d1664 228 Pfam PF11769 Protein of unknown function (DUF3313) 16 200 3.2E-28 T 14-10-2018 IPR021747 Protein of unknown function DUF3313 D521_0389 e14e8958016a3f700ad12933063147ec 290 SUPERFAMILY SSF53850 93 289 2.71E-20 T 14-10-2018 D521_0389 e14e8958016a3f700ad12933063147ec 290 Gene3D G3DSA:3.40.190.290 94 290 2.0E-10 T 14-10-2018 D521_0389 e14e8958016a3f700ad12933063147ec 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.8E-15 T 14-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 D521_0389 e14e8958016a3f700ad12933063147ec 290 Gene3D G3DSA:1.10.10.10 4 89 8.0E-19 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0389 e14e8958016a3f700ad12933063147ec 290 Pfam PF03466 LysR substrate binding domain 117 288 2.0E-12 T 14-10-2018 IPR005119 LysR, substrate-binding D521_0389 e14e8958016a3f700ad12933063147ec 290 SUPERFAMILY SSF46785 4 86 6.86E-18 T 14-10-2018 IPR036390 Winged helix DNA-binding domain superfamily D521_0673 7ef1e7cc7ebd6782d3832840e70b1e78 149 Gene3D G3DSA:3.10.20.30 1 73 1.6E-30 T 14-10-2018 IPR012675 Beta-grasp domain superfamily D521_0673 7ef1e7cc7ebd6782d3832840e70b1e78 149 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 14-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 D521_0673 7ef1e7cc7ebd6782d3832840e70b1e78 149 SUPERFAMILY SSF47741 83 148 8.37E-26 T 14-10-2018 IPR036884 [2Fe-2S]-binding domain superfamily D521_0673 7ef1e7cc7ebd6782d3832840e70b1e78 149 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 5 60 1.3E-8 T 14-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 D521_0673 7ef1e7cc7ebd6782d3832840e70b1e78 149 Pfam PF01799 [2Fe-2S] binding domain 72 143 1.8E-24 T 14-10-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 D521_0673 7ef1e7cc7ebd6782d3832840e70b1e78 149 Gene3D G3DSA:1.10.150.120 74 149 2.7E-23 T 14-10-2018 D521_0673 7ef1e7cc7ebd6782d3832840e70b1e78 149 SUPERFAMILY SSF54292 2 77 1.44E-26 T 14-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 D521_0295 429756e942e6e797d9e0d013e48654e8 69 Pfam PF11903 ParD-like antitoxin of type II bacterial toxin-antitoxin system 5 59 5.8E-16 T 14-10-2018 IPR021831 ParD-like antitoxin of type II bacterial toxin-antitoxin system D521_1528 23d06db58a4487cbe6f938db8483a9c6 480 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 16 445 2.4E-117 T 14-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1528 23d06db58a4487cbe6f938db8483a9c6 480 Gene3D G3DSA:1.20.210.10 5 473 4.6E-207 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1528 23d06db58a4487cbe6f938db8483a9c6 480 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 11 476 1.6E-233 T 14-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 D521_1528 23d06db58a4487cbe6f938db8483a9c6 480 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 206 261 - T 14-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1528 23d06db58a4487cbe6f938db8483a9c6 480 SUPERFAMILY SSF81442 13 470 9.42E-126 T 14-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1655 901e62c68efe78dce7ccfffd9490f435 287 Pfam PF04536 TPM domain 40 162 6.8E-38 T 14-10-2018 IPR007621 TPM domain D521_1655 901e62c68efe78dce7ccfffd9490f435 287 Gene3D G3DSA:3.10.310.50 23 171 2.2E-47 T 14-10-2018 D521_2101 5a30a51d1abb4b62b1313fb6316b5d50 91 Gene3D G3DSA:3.30.2310.20 1 91 1.0E-7 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily D521_2101 5a30a51d1abb4b62b1313fb6316b5d50 91 SUPERFAMILY SSF143011 1 91 5.1E-15 T 14-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily D521_1554 2e18b1f622cbd9d1f1e7c594274d4458 231 Gene3D G3DSA:3.40.50.720 8 231 4.7E-32 T 14-10-2018 D521_1554 2e18b1f622cbd9d1f1e7c594274d4458 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1554 2e18b1f622cbd9d1f1e7c594274d4458 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 66 77 3.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1554 2e18b1f622cbd9d1f1e7c594274d4458 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 3.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1554 2e18b1f622cbd9d1f1e7c594274d4458 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 3.3E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1554 2e18b1f622cbd9d1f1e7c594274d4458 231 Pfam PF00106 short chain dehydrogenase 11 189 2.0E-8 T 14-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR D521_1554 2e18b1f622cbd9d1f1e7c594274d4458 231 SUPERFAMILY SSF51735 10 231 2.77E-38 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1790 d197d84efee762835ec641848eaff408 272 PRINTS PR00412 Epoxide hydrolase signature 107 120 1.4E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_1790 d197d84efee762835ec641848eaff408 272 PRINTS PR00412 Epoxide hydrolase signature 93 106 1.4E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_1790 d197d84efee762835ec641848eaff408 272 PRINTS PR00412 Epoxide hydrolase signature 30 48 1.4E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_1790 d197d84efee762835ec641848eaff408 272 PRINTS PR00412 Epoxide hydrolase signature 242 264 1.4E-5 T 14-10-2018 IPR000639 Epoxide hydrolase-like GO:0003824 D521_1790 d197d84efee762835ec641848eaff408 272 Pfam PF00561 alpha/beta hydrolase fold 25 252 2.1E-23 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1790 d197d84efee762835ec641848eaff408 272 Gene3D G3DSA:3.40.50.1820 4 268 4.4E-61 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1790 d197d84efee762835ec641848eaff408 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 6.3E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1790 d197d84efee762835ec641848eaff408 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 211 225 6.3E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1790 d197d84efee762835ec641848eaff408 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 6.3E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1790 d197d84efee762835ec641848eaff408 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 6.3E-12 T 14-10-2018 IPR000073 Alpha/beta hydrolase fold-1 D521_1790 d197d84efee762835ec641848eaff408 272 SUPERFAMILY SSF53474 7 266 2.68E-65 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0726 a77d4c1573b954fd29a5049d79730955 221 Gene3D G3DSA:3.40.50.10610 33 207 1.2E-11 T 14-10-2018 D521_0726 a77d4c1573b954fd29a5049d79730955 221 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 47 202 5.1E-10 T 14-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component D521_0726 a77d4c1573b954fd29a5049d79730955 221 SUPERFAMILY SSF159594 46 205 2.22E-20 T 14-10-2018 D521_0684 baf2460b411d16b83ade6479591786c1 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 136 2.6E-32 T 14-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 D521_0684 baf2460b411d16b83ade6479591786c1 137 Gene3D G3DSA:3.30.420.270 63 132 6.4E-12 T 14-10-2018 D521_1261 497c9af26734afa059284bd0921d7148 249 Gene3D G3DSA:1.10.287.610 102 149 1.1E-84 T 14-10-2018 D521_1261 497c9af26734afa059284bd0921d7148 249 SUPERFAMILY SSF52313 5 230 9.55E-89 T 14-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily D521_1261 497c9af26734afa059284bd0921d7148 249 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 225 6.5E-94 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1261 497c9af26734afa059284bd0921d7148 249 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 1 224 38.689 T 14-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1261 497c9af26734afa059284bd0921d7148 249 Pfam PF00318 Ribosomal protein S2 8 223 2.9E-88 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1261 497c9af26734afa059284bd0921d7148 249 Gene3D G3DSA:3.40.50.10490 7 218 1.1E-84 T 14-10-2018 D521_1261 497c9af26734afa059284bd0921d7148 249 PRINTS PR00395 Ribosomal protein S2 signature 36 45 2.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1261 497c9af26734afa059284bd0921d7148 249 PRINTS PR00395 Ribosomal protein S2 signature 86 103 2.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1261 497c9af26734afa059284bd0921d7148 249 PRINTS PR00395 Ribosomal protein S2 signature 157 174 2.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1261 497c9af26734afa059284bd0921d7148 249 PRINTS PR00395 Ribosomal protein S2 signature 195 209 2.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1261 497c9af26734afa059284bd0921d7148 249 PRINTS PR00395 Ribosomal protein S2 signature 174 185 2.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_1261 497c9af26734afa059284bd0921d7148 249 PRINTS PR00395 Ribosomal protein S2 signature 5 23 2.2E-34 T 14-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 D521_0302 ce2796f08074a54243d90e5cf43cb40c 263 Pfam PF01227 GTP cyclohydrolase I 81 260 2.4E-51 T 14-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 D521_0302 ce2796f08074a54243d90e5cf43cb40c 263 Gene3D G3DSA:3.30.1130.10 127 263 4.5E-40 T 14-10-2018 D521_0302 ce2796f08074a54243d90e5cf43cb40c 263 Gene3D G3DSA:1.10.286.10 52 126 5.4E-8 T 14-10-2018 D521_0302 ce2796f08074a54243d90e5cf43cb40c 263 SUPERFAMILY SSF55620 46 261 4.22E-61 T 14-10-2018 D521_1816 f7671b7f0b5f3d2923f9cae1476442c4 144 SUPERFAMILY SSF54427 13 128 7.71E-18 T 14-10-2018 IPR032710 NTF2-like domain superfamily D521_1816 f7671b7f0b5f3d2923f9cae1476442c4 144 Pfam PF13474 SnoaL-like domain 13 127 1.3E-13 T 14-10-2018 IPR037401 SnoaL-like domain D521_1816 f7671b7f0b5f3d2923f9cae1476442c4 144 Gene3D G3DSA:3.10.450.50 4 141 1.4E-19 T 14-10-2018 D521_0756 7eba2ebd6910115ac50ff61c0a59650c 102 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 3 102 20.024 T 14-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 D521_0756 7eba2ebd6910115ac50ff61c0a59650c 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 97 1.3E-21 T 14-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like D521_1453 b91e3681e4c5500199ed74b7d964c813 319 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 319 54.429 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 D521_1453 b91e3681e4c5500199ed74b7d964c813 319 Pfam PF03186 CobD/Cbib protein 15 260 3.6E-20 T 14-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 D521_0074 a6b81fed3b226476ea2d0ed323d323c2 38 Pfam PF00444 Ribosomal protein L36 1 38 4.8E-16 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0074 a6b81fed3b226476ea2d0ed323d323c2 38 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 38 15.777 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0074 a6b81fed3b226476ea2d0ed323d323c2 38 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 38 7.4E-18 T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0074 a6b81fed3b226476ea2d0ed323d323c2 38 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 37 - T 14-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0074 a6b81fed3b226476ea2d0ed323d323c2 38 SUPERFAMILY SSF57840 1 38 6.67E-14 T 14-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0824 52b482c637843ebce04923f3d0cbe85f 132 Pfam PF09842 Predicted membrane protein (DUF2069) 14 113 4.0E-30 T 14-10-2018 IPR018643 Protein of unknown function DUF2069, membrane D521_1217 7c927c138206035f0b336a59282fe632 936 SUPERFAMILY SSF53335 165 614 9.25E-50 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_1217 7c927c138206035f0b336a59282fe632 936 Gene3D G3DSA:3.40.50.150 292 624 3.3E-31 T 14-10-2018 D521_1217 7c927c138206035f0b336a59282fe632 936 Pfam PF02384 N-6 DNA Methylase 365 506 4.7E-5 T 14-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 D521_0207 206409666e6bf1a706455aac869c45d3 391 Gene3D G3DSA:1.10.620.20 47 384 6.8E-111 T 14-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 D521_0207 206409666e6bf1a706455aac869c45d3 391 Pfam PF00268 Ribonucleotide reductase, small chain 71 358 1.9E-83 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0207 206409666e6bf1a706455aac869c45d3 391 SUPERFAMILY SSF47240 55 362 7.64E-93 T 14-10-2018 IPR009078 Ferritin-like superfamily D521_0207 206409666e6bf1a706455aac869c45d3 391 PIRSF PIRSF000355 42 391 1.8E-132 T 14-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 D521_0910 294624ad4f68179dd3ba1fae5ead8f9c 154 SUPERFAMILY SSF54593 3 145 3.61E-16 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase D521_0910 294624ad4f68179dd3ba1fae5ead8f9c 154 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 11 121 3.8E-21 T 14-10-2018 D521_0910 294624ad4f68179dd3ba1fae5ead8f9c 154 Gene3D G3DSA:3.10.180.10 6 146 4.5E-20 T 14-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase D521_1744 a0c60da1bb78820e2dbadec06d80ea98 329 Pfam PF01594 AI-2E family transporter 3 315 2.8E-52 T 14-10-2018 IPR002549 Transmembrane protein TqsA-like D521_0989 ad1de2b915b5f21e6fc0b3ab0c5ce861 102 SUPERFAMILY SSF57652 22 102 3.4E-25 T 14-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 D521_0989 ad1de2b915b5f21e6fc0b3ab0c5ce861 102 Pfam PF01355 High potential iron-sulfur protein 34 99 1.1E-23 T 14-10-2018 IPR000170 High potential iron-sulphur protein GO:0009055|GO:0019646 D521_0989 ad1de2b915b5f21e6fc0b3ab0c5ce861 102 Gene3D G3DSA:4.10.490.10 27 102 3.8E-24 T 14-10-2018 IPR036369 High potential iron-sulphur protein superfamily GO:0009055|GO:0019646 D521_0882 54e44f018162c417c0cb326e3ef9dbf9 337 Pfam PF02558 Ketopantoate reductase PanE/ApbA 5 173 4.5E-25 T 14-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain D521_0882 54e44f018162c417c0cb326e3ef9dbf9 337 Gene3D G3DSA:3.40.50.720 1 196 1.4E-62 T 14-10-2018 D521_0882 54e44f018162c417c0cb326e3ef9dbf9 337 SUPERFAMILY SSF48179 199 320 1.87E-28 T 14-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 D521_0882 54e44f018162c417c0cb326e3ef9dbf9 337 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 199 319 1.9E-25 T 14-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain D521_0882 54e44f018162c417c0cb326e3ef9dbf9 337 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 3 322 2.0E-56 T 14-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 D521_0882 54e44f018162c417c0cb326e3ef9dbf9 337 Gene3D G3DSA:1.10.1040.10 199 332 8.0E-39 T 14-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 D521_0882 54e44f018162c417c0cb326e3ef9dbf9 337 SUPERFAMILY SSF51735 1 154 1.24E-20 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_1375 828a7ac52d21ec24ec85586e6b95b31b 125 Pfam PF13664 Domain of unknown function (DUF4149) 6 95 2.6E-11 T 14-10-2018 IPR025423 Domain of unknown function DUF4149 D521_0736 982bdabd9f31d3ce204bd47a96bcf9c5 215 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 7 212 36.393 T 14-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 D521_0736 982bdabd9f31d3ce204bd47a96bcf9c5 215 Pfam PF02666 Phosphatidylserine decarboxylase 44 206 8.0E-30 T 14-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 D521_0736 982bdabd9f31d3ce204bd47a96bcf9c5 215 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 8 212 7.5E-66 T 14-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 D521_0335 917134966fa328b6062214e61701adf3 125 Pfam PF09722 Protein of unknown function (DUF2384) 76 122 2.7E-8 T 14-10-2018 IPR024467 Domain of unknown function DUF2384 D521_0944 2ba3c4e4dcd9125e4ab8cb31b295f7a6 321 PIRSF PIRSF005261 1 308 3.2E-63 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 D521_0944 2ba3c4e4dcd9125e4ab8cb31b295f7a6 321 SUPERFAMILY SSF64397 2 258 6.8E-51 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 D521_0944 2ba3c4e4dcd9125e4ab8cb31b295f7a6 321 Gene3D G3DSA:3.55.30.10 1 188 3.2E-49 T 14-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 D521_0944 2ba3c4e4dcd9125e4ab8cb31b295f7a6 321 Pfam PF01430 Hsp33 protein 3 297 9.7E-73 T 14-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 D521_0944 2ba3c4e4dcd9125e4ab8cb31b295f7a6 321 Gene3D G3DSA:3.90.1280.10 250 308 7.9E-22 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 D521_0944 2ba3c4e4dcd9125e4ab8cb31b295f7a6 321 Gene3D G3DSA:1.10.287.480 199 249 4.1E-11 T 14-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily D521_0944 2ba3c4e4dcd9125e4ab8cb31b295f7a6 321 SUPERFAMILY SSF118352 249 306 7.72E-18 T 14-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 D521_1196 d9fcc22950bb528e97f2ddd7ecb53d7e 336 Pfam PF01384 Phosphate transporter family 25 325 3.0E-90 T 14-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 D521_1896 0c0fce6d75a8a37ae26439ba24303c8e 302 Pfam PF06189 5'-nucleotidase 39 298 1.4E-109 T 14-10-2018 IPR010394 5-nucleotidase GO:0000166|GO:0000287|GO:0005737|GO:0008253|GO:0009117 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821|Reactome: R-HSA-74259 D521_1543 08e093497c5404304e70f1565fb5f7a1 158 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 1 158 1.8E-48 T 14-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 D521_1543 08e093497c5404304e70f1565fb5f7a1 158 Gene3D G3DSA:3.40.50.300 1 155 1.4E-29 T 14-10-2018 D521_1543 08e093497c5404304e70f1565fb5f7a1 158 SUPERFAMILY SSF52540 1 147 4.18E-28 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_1543 08e093497c5404304e70f1565fb5f7a1 158 Pfam PF00005 ABC transporter 1 116 4.1E-15 T 14-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 D521_0083 6fb96d2fcef6a3f249f94fbe3af8d571 221 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 204 3.2E-63 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 D521_0083 6fb96d2fcef6a3f249f94fbe3af8d571 221 Pfam PF01926 50S ribosome-binding GTPase 26 148 2.9E-18 T 14-10-2018 IPR006073 GTP binding domain GO:0005525 D521_0083 6fb96d2fcef6a3f249f94fbe3af8d571 221 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 9 209 26.386 T 14-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 D521_0083 6fb96d2fcef6a3f249f94fbe3af8d571 221 Gene3D G3DSA:3.40.50.300 2 220 1.3E-51 T 14-10-2018 D521_0083 6fb96d2fcef6a3f249f94fbe3af8d571 221 SUPERFAMILY SSF52540 9 208 2.68E-30 T 14-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase D521_0469 a786f4890ff400a3e4ff454d49572ba9 113 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 10 108 1.3E-9 T 14-10-2018 IPR008407 Branched-chain amino acid transport, AzlD D521_0292 716867ab9868263d1b2789c6f0abbe76 287 Pfam PF12281 Nucleotidyltransferase 48 257 5.8E-55 T 14-10-2018 IPR022550 Nucleotidyltransferase 8 D521_1240 695e8a1603680fa8fb315b26b0692f72 122 Pfam PF02656 Domain of unknown function (DUF202) 5 80 7.8E-14 T 14-10-2018 IPR003807 Domain of unknown function DUF202 D521_0225 ac0fe38cabb1cd42c7de6962a93427d3 181 PIRSF PIRSF006162 3 137 5.4E-29 T 14-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 D521_0225 ac0fe38cabb1cd42c7de6962a93427d3 181 PIRSF PIRSF006162 144 181 0.0075 T 14-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 D521_0225 ac0fe38cabb1cd42c7de6962a93427d3 181 SUPERFAMILY SSF101307 8 174 3.79E-27 T 14-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 D521_0225 ac0fe38cabb1cd42c7de6962a93427d3 181 Pfam PF04608 Phosphatidylglycerophosphatase A 14 173 3.4E-46 T 14-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 D521_2048 747fd4c5189f885f66b2a6eb13290c4a 188 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 46 172 3.4E-10 T 14-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 D521_2048 747fd4c5189f885f66b2a6eb13290c4a 188 Gene3D G3DSA:3.30.530.20 39 182 1.3E-19 T 14-10-2018 IPR023393 START-like domain superfamily D521_2048 747fd4c5189f885f66b2a6eb13290c4a 188 SUPERFAMILY SSF55961 40 176 2.01E-19 T 14-10-2018 D521_1567 bda67a3a9dcefc883e63fe8a9f6a3a27 200 Pfam PF00881 Nitroreductase family 7 177 9.8E-32 T 14-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 D521_1567 bda67a3a9dcefc883e63fe8a9f6a3a27 200 Gene3D G3DSA:3.40.109.10 1 194 1.3E-47 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 D521_1567 bda67a3a9dcefc883e63fe8a9f6a3a27 200 SUPERFAMILY SSF55469 1 186 1.23E-51 T 14-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 D521_1230 00616989500200fcdf8d2e9af87c68ed 335 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 329 3.0E-101 T 14-10-2018 IPR007296 Domain of unknown function DUF403 D521_0731 ebb9560819b7d5f977151f89501b118a 154 Pfam PF12279 Protein of unknown function (DUF3619) 13 135 2.9E-37 T 14-10-2018 IPR022064 Protein of unknown function DUF3619 D521_0644 13e1fcb2f9ffb92ded74fa375b10b358 322 Pfam PF00482 Type II secretion system (T2SS), protein F 157 279 1.9E-16 T 14-10-2018 IPR018076 Type II secretion system F domain D521_0644 13e1fcb2f9ffb92ded74fa375b10b358 322 Gene3D G3DSA:1.20.81.30 142 257 4.7E-8 T 14-10-2018 D521_0810 391601ac058f1632b6a9e20ac7a90b44 275 Gene3D G3DSA:2.40.320.10 8 200 8.8E-8 T 14-10-2018 D521_0810 391601ac058f1632b6a9e20ac7a90b44 275 SUPERFAMILY SSF55154 55 100 3.92E-5 T 14-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 D521_1337 dfcabd7a2b5031b42fd8afad95716ed1 203 Gene3D G3DSA:3.20.130.10 4 182 7.4E-51 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 D521_1337 dfcabd7a2b5031b42fd8afad95716ed1 203 SUPERFAMILY SSF117457 3 182 3.92E-42 T 14-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 D521_1337 dfcabd7a2b5031b42fd8afad95716ed1 203 Pfam PF05683 Fumarase C-terminus 7 183 4.5E-29 T 14-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 D521_1201 a4bc5b59e737e0b17d2435474442f861 498 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 50 227 1.8E-16 T 14-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like D521_2091 74df6990b8ae3f7aff14af903c6289f7 322 Pfam PF13280 WYL domain 145 318 9.1E-37 T 14-10-2018 IPR026881 WYL domain D521_1088 903e6157a93a6726f9027585ab677ba0 472 Pfam PF04966 Carbohydrate-selective porin, OprB family 79 472 1.8E-26 T 14-10-2018 IPR007049 Carbohydrate-selective porin OprB GO:0008643|GO:0015288|GO:0016021 D521_1088 903e6157a93a6726f9027585ab677ba0 472 Gene3D G3DSA:2.40.160.180 118 472 2.6E-15 T 14-10-2018 IPR038673 Carbohydrate-selective porin OprB superfamily D521_1406 dc64c011fff1b2fa00cf94f02c2bfd16 466 SUPERFAMILY SSF55073 337 426 3.53E-7 T 14-10-2018 IPR029787 Nucleotide cyclase D521_1406 dc64c011fff1b2fa00cf94f02c2bfd16 466 Gene3D G3DSA:3.30.70.270 327 461 3.0E-8 T 14-10-2018 D521_0949 269f4994f9d7d008aa7433da7ded7442 141 Gene3D G3DSA:3.40.50.1820 1 141 7.0E-37 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_0949 269f4994f9d7d008aa7433da7ded7442 141 Pfam PF05728 Uncharacterised protein family (UPF0227) 4 139 2.2E-33 T 14-10-2018 IPR008886 Uncharacterised protein family UPF0227/Esterase YqiA D521_0949 269f4994f9d7d008aa7433da7ded7442 141 SUPERFAMILY SSF53474 5 140 1.74E-13 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1763 2e474678bf1ce339b12dc6fe1dfc7ce3 501 SUPERFAMILY SSF55103 207 476 1.46E-69 T 14-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 D521_1763 2e474678bf1ce339b12dc6fe1dfc7ce3 501 Gene3D G3DSA:3.30.465.40 28 253 5.1E-60 T 14-10-2018 D521_1763 2e474678bf1ce339b12dc6fe1dfc7ce3 501 Gene3D G3DSA:3.30.70.2740 352 433 1.3E-7 T 14-10-2018 D521_1763 2e474678bf1ce339b12dc6fe1dfc7ce3 501 SUPERFAMILY SSF56176 21 233 4.58E-65 T 14-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 D521_1763 2e474678bf1ce339b12dc6fe1dfc7ce3 501 Pfam PF02913 FAD linked oxidases, C-terminal domain 232 472 6.0E-65 T 14-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 D521_1763 2e474678bf1ce339b12dc6fe1dfc7ce3 501 Pfam PF01565 FAD binding domain 58 196 6.4E-36 T 14-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 D521_1721 3841939504291c7b50ee6d7e0d8eb020 397 Pfam PF00487 Fatty acid desaturase 23 226 3.0E-12 T 14-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 D521_1721 3841939504291c7b50ee6d7e0d8eb020 397 Pfam PF01610 Transposase 278 396 1.9E-10 T 14-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain D521_0232 c4b67cc8100345c376b79cf2683cd190 239 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 26 178 35.839 T 14-10-2018 IPR026592 Outer membrane protein assembly factor BamE D521_0232 c4b67cc8100345c376b79cf2683cd190 239 Pfam PF04355 SmpA / OmlA family 66 136 7.1E-23 T 14-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 D521_0232 c4b67cc8100345c376b79cf2683cd190 239 Gene3D G3DSA:3.30.1450.10 73 148 3.2E-26 T 14-10-2018 IPR037873 BamE-like D521_1338 449a7f08f9d7c8f09d05ee3d0d774cbe 287 Pfam PF05681 Fumarate hydratase (Fumerase) 6 276 2.1E-88 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 D521_1338 449a7f08f9d7c8f09d05ee3d0d774cbe 287 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 4 276 1.4E-87 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 D521_0110 abf535b9a70b90896baaa4fee9ad370f 253 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 236 1.1E-76 T 14-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 D521_0110 abf535b9a70b90896baaa4fee9ad370f 253 Gene3D G3DSA:3.20.20.70 1 242 4.7E-83 T 14-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 D521_0110 abf535b9a70b90896baaa4fee9ad370f 253 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 240 35.503 T 14-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 D521_0110 abf535b9a70b90896baaa4fee9ad370f 253 Pfam PF00977 Histidine biosynthesis protein 3 232 1.1E-76 T 14-10-2018 IPR006062 Histidine biosynthesis GO:0000105 D521_0110 abf535b9a70b90896baaa4fee9ad370f 253 SUPERFAMILY SSF51366 1 240 6.91E-73 T 14-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 D521_1317 3f029e6c288ec66b35e239f225221c5e 286 PIRSF PIRSF005902 3 273 1.3E-62 T 14-10-2018 IPR001130 TatD family GO:0016788 D521_1317 3f029e6c288ec66b35e239f225221c5e 286 Pfam PF01026 TatD related DNase 11 268 6.9E-62 T 14-10-2018 IPR001130 TatD family GO:0016788 D521_1317 3f029e6c288ec66b35e239f225221c5e 286 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 203 219 - T 14-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 D521_1317 3f029e6c288ec66b35e239f225221c5e 286 SUPERFAMILY SSF51556 10 268 4.79E-72 T 14-10-2018 IPR032466 Metal-dependent hydrolase D521_1317 3f029e6c288ec66b35e239f225221c5e 286 Gene3D G3DSA:3.20.20.140 8 269 8.9E-71 T 14-10-2018 D521_1748 124f2fe069d9fe85085e50fb851371f7 175 SUPERFAMILY SSF55083 1 147 3.79E-46 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 D521_1748 124f2fe069d9fe85085e50fb851371f7 175 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 132 7.9E-34 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 D521_1748 124f2fe069d9fe85085e50fb851371f7 175 Gene3D G3DSA:3.30.70.560 1 159 1.4E-45 T 14-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 D521_1748 124f2fe069d9fe85085e50fb851371f7 175 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 132 5.5E-35 T 14-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 D521_1851 f10a2938c3a0549b05ec5777cc4fc873 136 SMART SM00450 21 125 2.4E-18 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1851 f10a2938c3a0549b05ec5777cc4fc873 136 Gene3D G3DSA:3.40.250.10 2 132 2.6E-32 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1851 f10a2938c3a0549b05ec5777cc4fc873 136 SUPERFAMILY SSF52821 6 129 6.81E-28 T 14-10-2018 IPR036873 Rhodanese-like domain superfamily D521_1851 f10a2938c3a0549b05ec5777cc4fc873 136 Pfam PF00581 Rhodanese-like domain 25 122 3.2E-17 T 14-10-2018 IPR001763 Rhodanese-like domain D521_1056 0aa33e7763c1c941107ed08939e65add 61 Pfam PF11127 Protein of unknown function (DUF2892) 1 60 1.7E-20 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 D521_1548 66d05ccd27c747eec2f48a2367ec9a4f 150 Pfam PF10504 Protein of unknown function (DUF2452) 32 139 9.8E-8 T 14-10-2018 IPR019534 Protein of unknown function DUF2452 D521_0818 8bda47a4d15d62fb43c4f46b93c58d45 87 SUPERFAMILY SSF47473 31 82 2.02E-7 T 14-10-2018 IPR011992 EF-hand domain pair D521_0818 8bda47a4d15d62fb43c4f46b93c58d45 87 Gene3D G3DSA:1.10.238.10 27 87 1.5E-9 T 14-10-2018 D521_1815 a5257de404198afa236e92909f5ea34a 345 SUPERFAMILY SSF53756 3 344 9.1E-92 T 14-10-2018 D521_1815 a5257de404198afa236e92909f5ea34a 345 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 71 326 2.9E-56 T 14-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 D521_1815 a5257de404198afa236e92909f5ea34a 345 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 3 344 1.5E-116 T 14-10-2018 IPR011910 ADP-heptose--LPS heptosyltransferase 2 GO:0009103|GO:0016757 D521_1815 a5257de404198afa236e92909f5ea34a 345 Gene3D G3DSA:3.40.50.2000 2 150 2.3E-50 T 14-10-2018 D521_1815 a5257de404198afa236e92909f5ea34a 345 Gene3D G3DSA:3.40.50.2000 169 345 5.5E-58 T 14-10-2018 D521_0625 7a40918bc531a4cf877f29831fddc3cd 257 Pfam PF01925 Sulfite exporter TauE/SafE 13 249 2.6E-38 T 14-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 D521_2108 8e80a8a438fe90dfe138fe819ad18431 288 Gene3D G3DSA:3.30.2010.10 56 149 5.9E-31 T 14-10-2018 D521_2108 8e80a8a438fe90dfe138fe819ad18431 288 Pfam PF01435 Peptidase family M48 66 278 1.6E-40 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 D521_2108 8e80a8a438fe90dfe138fe819ad18431 288 Hamap MF_00188 Protease HtpX [htpX]. 4 278 28.772 T 14-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 D521_1432 1dc79e17eb19078e11564987e48d30eb 192 Pfam PF02620 Uncharacterized ACR, COG1399 77 190 4.6E-18 T 14-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD D521_1817 c87ed4723f947e269cc3b4419775563b 204 Pfam PF11161 Protein of unknown function (DUF2946) 1 202 4.2E-63 T 14-10-2018 IPR021332 Protein of unknown function DUF2944 D521_0033 771a075358d54be26297f1ea5f380245 114 PRINTS PR00606 Class ID cytochrome C signature 48 61 2.9E-17 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 D521_0033 771a075358d54be26297f1ea5f380245 114 PRINTS PR00606 Class ID cytochrome C signature 98 108 2.9E-17 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 D521_0033 771a075358d54be26297f1ea5f380245 114 PRINTS PR00606 Class ID cytochrome C signature 86 96 2.9E-17 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 D521_0033 771a075358d54be26297f1ea5f380245 114 PRINTS PR00606 Class ID cytochrome C signature 33 46 2.9E-17 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 D521_0033 771a075358d54be26297f1ea5f380245 114 PRINTS PR00606 Class ID cytochrome C signature 71 84 2.9E-17 T 14-10-2018 IPR002324 Cytochrome c, class ID GO:0005506|GO:0009055|GO:0020037 D521_0033 771a075358d54be26297f1ea5f380245 114 SUPERFAMILY SSF46626 32 107 6.15E-15 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0033 771a075358d54be26297f1ea5f380245 114 Gene3D G3DSA:1.10.760.10 30 109 5.4E-27 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1273 662eb97f900f75709e33caaf1bcfffce 646 Pfam PF02705 K+ potassium transporter 35 567 8.8E-207 T 14-10-2018 IPR003855 Potassium transporter GO:0015079|GO:0016020|GO:0071805 D521_1273 662eb97f900f75709e33caaf1bcfffce 646 Hamap MF_01522 Low affinity potassium transport system protein kup [kup]. 26 646 33.29 T 14-10-2018 IPR023051 Potassium uptake protein, low affinity, Kup D521_1536 484af508ae88f174b069a1f4ebf846b1 166 Pfam PF03918 Cytochrome C biogenesis protein 15 153 2.1E-50 T 14-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family D521_1536 484af508ae88f174b069a1f4ebf846b1 166 Gene3D G3DSA:1.10.8.640 26 110 3.3E-30 T 14-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily D521_2106 a9fab63065e8330797529aec21fa1778 193 Pfam PF14334 Domain of unknown function (DUF4390) 25 181 1.1E-55 T 14-10-2018 IPR025500 Protein of unknown function DUF4390 D521_0259 851426d4ab3b56f260d17936fe8fb630 152 Pfam PF11026 Protein of unknown function (DUF2721) 15 143 5.0E-26 T 14-10-2018 IPR021279 Protein of unknown function DUF2721 D521_0967 060458bda5eb23b0b4d9f94e5e81b14c 85 Pfam PF06945 Protein of unknown function (DUF1289) 26 70 1.1E-15 T 14-10-2018 IPR010710 Protein of unknown function DUF1289 D521_1500 f2b41e7b7ae7932305cdc592cba0057a 162 Pfam PF02417 Chromate transporter 3 147 9.7E-26 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 D521_0351 3359ab5a764b3ee9d0598a7895ee4784 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 276 6.3E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 D521_1967 1c368a514ff7239f60e4a700066ba141 161 Gene3D G3DSA:3.40.50.620 28 145 3.4E-32 T 14-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold D521_1967 1c368a514ff7239f60e4a700066ba141 161 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 18 159 3.6E-58 T 14-10-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 D521_1967 1c368a514ff7239f60e4a700066ba141 161 SUPERFAMILY SSF52374 27 154 1.37E-21 T 14-10-2018 D521_1967 1c368a514ff7239f60e4a700066ba141 161 Pfam PF01467 Cytidylyltransferase-like 31 131 2.4E-15 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 D521_1967 1c368a514ff7239f60e4a700066ba141 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 29 94 2.9E-12 T 14-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 D521_1626 88e0521dfcac28472496a598f403343a 216 Pfam PF04403 Paraquat-inducible protein A 45 201 5.3E-52 T 14-10-2018 IPR007498 Intermembrane transport protein PqiA-like D521_1247 e8aa419a9955cd74d678cc6008675954 195 Hamap MF_00052_B Ribonuclease HII [rnhB]. 3 186 34.832 T 14-10-2018 IPR022898 Ribonuclease HII GO:0004523 D521_1247 e8aa419a9955cd74d678cc6008675954 195 SUPERFAMILY SSF53098 2 190 5.92E-67 T 14-10-2018 IPR012337 Ribonuclease H-like superfamily D521_1247 e8aa419a9955cd74d678cc6008675954 195 Pfam PF01351 Ribonuclease HII 5 185 2.1E-37 T 14-10-2018 IPR024567 Ribonuclease HII/HIII domain D521_1247 e8aa419a9955cd74d678cc6008675954 195 Gene3D G3DSA:3.30.420.10 1 195 6.5E-75 T 14-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 D521_0324 fac74be7fa5a0e5970159015d4de4f1b 297 SUPERFAMILY SSF53335 123 280 2.44E-20 T 14-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase D521_0324 fac74be7fa5a0e5970159015d4de4f1b 297 Pfam PF13489 Methyltransferase domain 130 272 7.5E-21 T 14-10-2018 D521_0324 fac74be7fa5a0e5970159015d4de4f1b 297 Gene3D G3DSA:3.40.50.150 102 287 2.5E-22 T 14-10-2018 D521_1079 fefbcfce42a16c65bf2c7b238fb29edc 233 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 23 225 4.5E-41 T 14-10-2018 IPR006214 Bax inhibitor 1-related D521_1237 cebc3d10c933b6e9d3a73d9351d604ce 306 Pfam PF05681 Fumarate hydratase (Fumerase) 21 288 2.6E-73 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 D521_1237 cebc3d10c933b6e9d3a73d9351d604ce 306 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 18 290 8.7E-96 T 14-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 D521_0176 e5b6a05e0b9cadd6309f534c8e48c342 166 Pfam PF08534 Redoxin 4 163 1.7E-38 T 14-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 D521_0176 e5b6a05e0b9cadd6309f534c8e48c342 166 SUPERFAMILY SSF52833 1 166 8.3E-36 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_0176 e5b6a05e0b9cadd6309f534c8e48c342 166 Gene3D G3DSA:3.40.30.10 1 166 3.3E-62 T 14-10-2018 D521_0842 bdca120ebe197a941915668c2429326a 116 Gene3D G3DSA:1.10.1660.10 21 96 9.7E-22 T 14-10-2018 D521_0842 bdca120ebe197a941915668c2429326a 116 SUPERFAMILY SSF46955 25 112 6.87E-18 T 14-10-2018 IPR009061 Putative DNA-binding domain superfamily D521_0842 bdca120ebe197a941915668c2429326a 116 Pfam PF13411 MerR HTH family regulatory protein 27 96 2.0E-22 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 D521_0842 bdca120ebe197a941915668c2429326a 116 SMART SM00422 27 97 1.1E-7 T 14-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 D521_1488 80d80157f1a4169df88f72c8dff22bad 583 Gene3D G3DSA:3.50.30.80 386 540 7.4E-49 T 14-10-2018 D521_1488 80d80157f1a4169df88f72c8dff22bad 583 SUPERFAMILY SSF143975 22 385 3.01E-116 T 14-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 D521_1488 80d80157f1a4169df88f72c8dff22bad 583 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 133 143 - T 14-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 D521_1488 80d80157f1a4169df88f72c8dff22bad 583 SUPERFAMILY SSF52016 387 572 1.73E-55 T 14-10-2018 D521_1488 80d80157f1a4169df88f72c8dff22bad 583 Pfam PF00920 Dehydratase family 50 565 2.7E-174 T 14-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 D521_1046 22b7e5097fa3c2f60049d03fc5e284ff 289 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 19 222 6.0E-20 T 14-10-2018 D521_0787 f4725efcb8d0bb1edd31aca12edd9dce 340 Gene3D G3DSA:3.40.190.10 26 323 3.3E-114 T 14-10-2018 D521_0787 f4725efcb8d0bb1edd31aca12edd9dce 340 PIRSF PIRSF002756 6 337 2.9E-102 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 D521_0787 f4725efcb8d0bb1edd31aca12edd9dce 340 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 25 332 2.9E-111 T 14-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 D521_0787 f4725efcb8d0bb1edd31aca12edd9dce 340 SUPERFAMILY SSF53850 25 333 1.32E-93 T 14-10-2018 D521_0787 f4725efcb8d0bb1edd31aca12edd9dce 340 Pfam PF12849 PBP superfamily domain 24 307 1.3E-61 T 14-10-2018 IPR024370 PBP domain D521_0787 f4725efcb8d0bb1edd31aca12edd9dce 340 Gene3D G3DSA:3.40.190.10 99 278 3.3E-114 T 14-10-2018 D521_0137 dee7434a0b6c89825e286db391dde3a7 108 Gene3D G3DSA:2.30.30.110 9 108 2.4E-20 T 14-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor D521_0137 dee7434a0b6c89825e286db391dde3a7 108 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 104 1.4E-18 T 14-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 D521_0137 dee7434a0b6c89825e286db391dde3a7 108 SUPERFAMILY SSF50118 1 107 1.39E-25 T 14-10-2018 D521_0976 311a45efcc0bfbe6c744e7562e050a44 85 SUPERFAMILY SSF46626 11 81 2.07E-6 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_1325 2aa6b23f965113a16c737c555b993ba3 161 Gene3D G3DSA:1.20.120.1630 2 160 3.0E-30 T 14-10-2018 D521_1325 2aa6b23f965113a16c737c555b993ba3 161 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 56 140 4.7E-10 T 14-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 D521_0898 5f322c110dbf18fad2f4419b2bea3b35 319 Gene3D G3DSA:3.40.50.720 164 312 6.6E-42 T 14-10-2018 D521_0898 5f322c110dbf18fad2f4419b2bea3b35 319 Pfam PF02625 XdhC and CoxI family 15 83 5.7E-23 T 14-10-2018 IPR003777 XdhC- CoxI D521_0898 5f322c110dbf18fad2f4419b2bea3b35 319 Pfam PF13478 XdhC Rossmann domain 165 306 5.2E-35 T 14-10-2018 IPR027051 XdhC Rossmann domain D521_0898 5f322c110dbf18fad2f4419b2bea3b35 319 SUPERFAMILY SSF51735 164 247 1.99E-9 T 14-10-2018 IPR036291 NAD(P)-binding domain superfamily D521_0299 8065eb8494f3fccd69d6355ac8449ccb 79 Gene3D G3DSA:2.10.260.10 2 79 1.2E-27 T 14-10-2018 D521_0299 8065eb8494f3fccd69d6355ac8449ccb 79 SUPERFAMILY SSF89447 6 56 4.18E-6 T 14-10-2018 IPR037914 SpoVT-AbrB domain superfamily D521_0299 8065eb8494f3fccd69d6355ac8449ccb 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 55 3.6E-6 T 14-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 D521_1319 d3ae250356938297ffb7cc2b938e1901 420 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 5 420 2.6E-139 T 14-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 D521_1319 d3ae250356938297ffb7cc2b938e1901 420 Pfam PF12704 MacB-like periplasmic core domain 35 249 4.9E-16 T 14-10-2018 IPR025857 MacB-like periplasmic core domain D521_1319 d3ae250356938297ffb7cc2b938e1901 420 Pfam PF02687 FtsX-like permease family 307 413 3.9E-11 T 14-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 D521_1893 7f4b2a06531f961b5c0aee5a4a0cd525 129 Gene3D G3DSA:3.30.2020.30 1 95 1.3E-26 T 14-10-2018 IPR038492 GBBH-like, N-terminal domain superfamily Reactome: R-HSA-71262 D521_1893 7f4b2a06531f961b5c0aee5a4a0cd525 129 Pfam PF06155 Protein of unknown function (DUF971) 8 89 4.7E-28 T 14-10-2018 IPR010376 Gamma-butyrobetaine hydroxylase-like, N-terminal Reactome: R-HSA-71262 D521_0950 8122d6df4b58f46b6809b0069a5844db 334 Pfam PF11306 Protein of unknown function (DUF3108) 116 315 3.4E-9 T 14-10-2018 IPR021457 Protein of unknown function DUF3108 D521_0053 22611401eb31754cc1b4d926ccdfea52 206 Gene3D G3DSA:3.40.1370.10 5 206 1.1E-64 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 D521_0053 22611401eb31754cc1b4d926ccdfea52 206 Pfam PF00573 Ribosomal protein L4/L1 family 17 203 2.6E-62 T 14-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 D521_0053 22611401eb31754cc1b4d926ccdfea52 206 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 203 5.1E-71 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_0053 22611401eb31754cc1b4d926ccdfea52 206 SUPERFAMILY SSF52166 1 205 3.53E-66 T 14-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 D521_0053 22611401eb31754cc1b4d926ccdfea52 206 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 8 206 30.53 T 14-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 D521_1194 ee3f045d77b72db8da25d973b4d08518 179 Pfam PF11749 Protein of unknown function (DUF3305) 3 166 1.0E-49 T 14-10-2018 IPR021736 Protein of unknown function DUF3305 D521_1768 a3e08fc684f8b907b63c45d008e0db34 285 Pfam PF01040 UbiA prenyltransferase family 23 268 4.2E-58 T 14-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 D521_1768 a3e08fc684f8b907b63c45d008e0db34 285 Gene3D G3DSA:1.10.357.140 15 180 7.1E-38 T 14-10-2018 D521_1768 a3e08fc684f8b907b63c45d008e0db34 285 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 62 84 - T 14-10-2018 IPR030470 UbiA prenyltransferase conserved site D521_1768 a3e08fc684f8b907b63c45d008e0db34 285 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 7 282 4.2E-94 T 14-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 D521_1768 a3e08fc684f8b907b63c45d008e0db34 285 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 1 283 27.496 T 14-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 D521_1576 a9dab28e397899dcca37f854941ee051 216 Pfam PF12973 ChrR Cupin-like domain 127 212 1.3E-35 T 14-10-2018 IPR025979 ChrR-like cupin domain D521_1576 a9dab28e397899dcca37f854941ee051 216 Pfam PF12973 ChrR Cupin-like domain 19 108 9.9E-39 T 14-10-2018 IPR025979 ChrR-like cupin domain D521_1576 a9dab28e397899dcca37f854941ee051 216 Gene3D G3DSA:2.60.120.10 1 116 1.5E-47 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_1576 a9dab28e397899dcca37f854941ee051 216 Gene3D G3DSA:2.60.120.10 117 215 2.7E-30 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_1576 a9dab28e397899dcca37f854941ee051 216 SUPERFAMILY SSF51182 113 215 1.0E-24 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily D521_1576 a9dab28e397899dcca37f854941ee051 216 SUPERFAMILY SSF51182 3 112 5.81E-32 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily D521_0118 b2aa524b719ac319fa661bd7735af4f7 491 SUPERFAMILY SSF81901 211 416 1.5E-11 T 14-10-2018 D521_0118 b2aa524b719ac319fa661bd7735af4f7 491 Gene3D G3DSA:1.25.40.10 102 372 2.6E-15 T 14-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 D521_1468 3d8f38db00f26ca3103df6fc278e6184 131 Gene3D G3DSA:1.10.150.280 18 90 6.6E-17 T 14-10-2018 D521_1468 3d8f38db00f26ca3103df6fc278e6184 131 SUPERFAMILY SSF47781 22 84 4.11E-19 T 14-10-2018 IPR010994 RuvA domain 2-like D521_1468 3d8f38db00f26ca3103df6fc278e6184 131 Pfam PF12836 Helix-hairpin-helix motif 23 81 2.2E-14 T 14-10-2018 D521_1468 3d8f38db00f26ca3103df6fc278e6184 131 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 24 82 1.9E-15 T 14-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain D521_1711 f8e3063d740a68e02a411c273a87ea02 500 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 438 2.6E-149 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane D521_1652 09625303b7342ba98f392c15ff5b9740 76 Pfam PF10982 Protein of unknown function (DUF2789) 1 75 3.7E-29 T 14-10-2018 IPR021250 Protein of unknown function DUF2789 D521_1652 09625303b7342ba98f392c15ff5b9740 76 Gene3D G3DSA:1.10.10.1130 1 76 1.3E-27 T 14-10-2018 D521_1227 84219e039e08b03e59a5e1b6aaa40bef 143 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 12 134 5.0E-28 T 14-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 D521_1227 84219e039e08b03e59a5e1b6aaa40bef 143 SUPERFAMILY SSF55961 1 143 4.66E-32 T 14-10-2018 D521_1227 84219e039e08b03e59a5e1b6aaa40bef 143 Gene3D G3DSA:3.30.530.20 4 143 1.0E-35 T 14-10-2018 IPR023393 START-like domain superfamily D521_0574 f598b6a35ec453373a575d3472277bbd 209 Pfam PF03922 OmpW family 30 209 2.5E-40 T 14-10-2018 IPR005618 Outer membrane protein, OmpW GO:0019867 D521_0574 f598b6a35ec453373a575d3472277bbd 209 Gene3D G3DSA:2.40.160.20 27 209 4.5E-51 T 14-10-2018 D521_0574 f598b6a35ec453373a575d3472277bbd 209 TIGRFAM TIGR01414 autotrans_barl: outer membrane autotransporter barrel domain 117 209 1.2E-4 T 14-10-2018 IPR006315 Outer membrane autotransporter barrel GO:0019867 D521_0574 f598b6a35ec453373a575d3472277bbd 209 SUPERFAMILY SSF56925 27 209 4.71E-27 T 14-10-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel D521_0685 b2ef0af26fe9dc3c84190957bbbc94be 230 Pfam PF01618 MotA/TolQ/ExbB proton channel family 102 209 1.2E-34 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel D521_0343 1b2a87538bdcf2bb9aee6d72c4806991 192 Pfam PF03729 Short repeat of unknown function (DUF308) 85 154 3.9E-12 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane D521_0343 1b2a87538bdcf2bb9aee6d72c4806991 192 Pfam PF03729 Short repeat of unknown function (DUF308) 30 96 1.0E-7 T 14-10-2018 IPR005325 Protein of unknown function DUF308, membrane D521_0099 7808a1458d857961d56be6b584f131fb 223 Pfam PF05494 MlaC protein 49 210 2.3E-56 T 14-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC D521_0099 7808a1458d857961d56be6b584f131fb 223 PIRSF PIRSF004649 14 223 1.3E-52 T 14-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC D521_0099 7808a1458d857961d56be6b584f131fb 223 Gene3D G3DSA:3.10.450.50 48 184 5.6E-62 T 14-10-2018 D521_0099 7808a1458d857961d56be6b584f131fb 223 Gene3D G3DSA:1.10.10.640 86 209 5.6E-62 T 14-10-2018 D521_2006 9e2b6e620087d63399fbb51dc390c43d 286 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 10 275 2.4E-31 T 14-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 D521_0739 bc3ec0cb192b7810a63310eb2b71f1ce 198 Pfam PF04366 Las17-binding protein actin regulator 108 198 7.2E-7 T 14-10-2018 IPR007461 Ysc84 actin-binding domain D521_0490 00624bbc87af112a4371fc49c0855235 384 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 8 380 3.5E-98 T 14-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 D521_0490 00624bbc87af112a4371fc49c0855235 384 Pfam PF03739 Predicted permease YjgP/YjgQ family 11 376 1.0E-62 T 14-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 D521_1310 906454649ecb8de5ba5cb703e29b70c6 107 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 10 101 1.2E-35 T 14-10-2018 IPR014056 Addiction module killer protein, predicted D521_1310 906454649ecb8de5ba5cb703e29b70c6 107 PIRSF PIRSF028744 1 106 1.1E-39 T 14-10-2018 IPR014056 Addiction module killer protein, predicted D521_0280 c209f1fead7f4f3c3485e82fdfb274c7 187 TIGRFAM TIGR02796 tolQ: protein TolQ 1 182 1.4E-72 T 14-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 D521_0280 c209f1fead7f4f3c3485e82fdfb274c7 187 Pfam PF01618 MotA/TolQ/ExbB proton channel family 48 170 1.2E-43 T 14-10-2018 IPR002898 MotA/TolQ/ExbB proton channel D521_0585 0d91ae30b4d0be2e2db71e8c0b72e1da 323 Gene3D G3DSA:3.40.190.150 28 312 4.2E-102 T 14-10-2018 D521_0585 0d91ae30b4d0be2e2db71e8c0b72e1da 323 Gene3D G3DSA:3.40.190.10 125 248 4.2E-102 T 14-10-2018 D521_0585 0d91ae30b4d0be2e2db71e8c0b72e1da 323 PIRSF PIRSF017082 5 322 9.6E-72 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0585 0d91ae30b4d0be2e2db71e8c0b72e1da 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 47 319 1.5E-78 T 14-10-2018 IPR005064 Bordetella uptake gene GO:0030288 D521_0585 0d91ae30b4d0be2e2db71e8c0b72e1da 323 SUPERFAMILY SSF53850 109 285 2.85E-13 T 14-10-2018 D521_0958 b4d2c7be1873c07dee2258c4282d2114 243 Pfam PF05742 Transport and Golgi organisation 2 1 219 9.8E-46 T 14-10-2018 IPR008551 Transport and Golgi organisation protein 2 D521_0856 7a0cabe5e0e9d57a3e04f2f58628cec5 408 Gene3D G3DSA:2.60.120.650 12 238 1.8E-74 T 14-10-2018 D521_0856 7a0cabe5e0e9d57a3e04f2f58628cec5 408 Pfam PF08007 Cupin superfamily protein 33 331 1.0E-71 T 14-10-2018 IPR003347 JmjC domain D521_0856 7a0cabe5e0e9d57a3e04f2f58628cec5 408 Gene3D G3DSA:1.10.10.2510 241 408 7.6E-10 T 14-10-2018 D521_0856 7a0cabe5e0e9d57a3e04f2f58628cec5 408 SUPERFAMILY SSF51197 25 320 5.91E-60 T 14-10-2018 D521_0677 65e973d61dc8c84ca39a68875d68c341 109 Pfam PF08770 Sulphur oxidation protein SoxZ 14 103 1.9E-22 T 14-10-2018 IPR014880 Sulphur oxidation protein SoxZ D521_0677 65e973d61dc8c84ca39a68875d68c341 109 SUPERFAMILY SSF81296 6 107 1.4E-23 T 14-10-2018 IPR014756 Immunoglobulin E-set D521_0677 65e973d61dc8c84ca39a68875d68c341 109 Gene3D G3DSA:2.60.40.10 2 109 1.1E-31 T 14-10-2018 IPR013783 Immunoglobulin-like fold D521_0513 9e05ed7dac8f1a1ded0327e82857f49f 62 Pfam PF11943 Protein of unknown function (DUF3460) 4 60 2.2E-24 T 14-10-2018 IPR021853 Protein of unknown function DUF3460 D521_0672 8f357ed67a9a8931506f651fd34e88a1 117 Pfam PF03788 LrgA family 12 105 1.1E-19 T 14-10-2018 IPR005538 LrgA/CidA family GO:0016021 D521_0768 f2765a4acf398a22b483d49c62845eeb 219 Pfam PF10263 SprT-like family 20 116 2.6E-12 T 14-10-2018 IPR006640 SprT-like D521_0138 df730e2f7a2021ef556f06a08028100f 71 Pfam PF11455 Protein of unknown function (DUF3018) 8 69 1.7E-25 T 14-10-2018 IPR021558 Protein of unknown function DUF3018 D521_0245 b10d4e3c5a096b30632c56b0ebf20599 272 Pfam PF02698 DUF218 domain 88 262 3.5E-25 T 14-10-2018 IPR003848 Domain of unknown function DUF218 D521_1962 c4c823a90a8812ca8926439657e4de34 238 Gene3D G3DSA:3.40.50.1820 1 230 1.9E-43 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1962 c4c823a90a8812ca8926439657e4de34 238 SUPERFAMILY SSF53474 36 222 3.76E-29 T 14-10-2018 IPR029058 Alpha/Beta hydrolase fold D521_1839 c8d3eafc60160a41404d8c3e75ae6386 441 PIRSF PIRSF006066 6 441 3.8E-70 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 D521_1839 c8d3eafc60160a41404d8c3e75ae6386 441 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 22 436 2.4E-89 T 14-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 D521_1839 c8d3eafc60160a41404d8c3e75ae6386 441 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 430 1.0E-82 T 14-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit D521_0478 2579898d871a42d853f5f94409318ec2 259 Pfam PF00535 Glycosyl transferase family 2 3 170 1.9E-22 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 D521_0478 2579898d871a42d853f5f94409318ec2 259 Pfam PF02709 N-terminal domain of galactosyltransferase 172 235 4.7E-11 T 14-10-2018 IPR027791 Galactosyltransferase, C-terminal Reactome: R-HSA-2022854|Reactome: R-HSA-975577 D521_0478 2579898d871a42d853f5f94409318ec2 259 SUPERFAMILY SSF53448 1 247 1.01E-44 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_0478 2579898d871a42d853f5f94409318ec2 259 Gene3D G3DSA:3.90.550.10 1 252 1.6E-51 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1275 2b8d5dff8a4e4828c282460fbe2ce17e 963 Pfam PF06634 Protein of unknown function (DUF1156) 11 82 7.4E-25 T 14-10-2018 IPR009537 Domain of unknown function DUF1156 D521_1840 c85ca108d8dce760b0d4bbf20ec17ea5 174 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 162 4.0E-26 T 14-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ D521_1460 33f4dfcdece964ab47d97a53ef77b3a4 119 Pfam PF03724 META domain 13 111 5.0E-24 T 14-10-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ D521_1460 33f4dfcdece964ab47d97a53ef77b3a4 119 Gene3D G3DSA:2.40.128.270 2 116 2.0E-24 T 14-10-2018 IPR038670 HslJ-like superfamily D521_1017 3fb97e104343ccb4d2c6ba0a63d5bf1c 258 Pfam PF03883 Peroxide stress protein YaaA 1 243 3.3E-88 T 14-10-2018 IPR005583 Peroxide stress protein YaaA D521_1017 3fb97e104343ccb4d2c6ba0a63d5bf1c 258 Hamap MF_00652 UPF0246 protein YaaA [yaaA]. 1 255 35.672 T 14-10-2018 IPR005583 Peroxide stress protein YaaA D521_1492 9b30e2f748a0bdd8a1aed292d69b4cef 58 Pfam PF10636 Hemin uptake protein hemP 22 58 2.0E-16 T 14-10-2018 IPR019600 Hemin uptake protein HemP D521_1492 9b30e2f748a0bdd8a1aed292d69b4cef 58 Gene3D G3DSA:2.10.70.10 19 58 2.8E-16 T 14-10-2018 D521_1849 e7b3e5c3cb05700b3b450903bc536858 95 Pfam PF13488 Glycine zipper 30 74 2.3E-10 T 14-10-2018 IPR039567 Glycine zipper domain D521_0387 e27474dec83f9d7dff0c71acd9ef3266 187 Pfam PF09361 Phasin protein 11 106 1.7E-8 T 14-10-2018 IPR018968 Phasin D521_0730 26f5ec82205ca6129e772a7e2f04e7a3 210 Pfam PF11304 Protein of unknown function (DUF3106) 55 154 2.1E-28 T 14-10-2018 IPR021455 Protein of unknown function DUF3106 D521_1740 1d5a47bd8ad00c5db99c8244eb34e8a5 280 Pfam PF13369 Transglutaminase-like superfamily 40 196 1.7E-41 T 14-10-2018 IPR032698 Protein SirB1, N-terminal Reactome: R-HSA-8951664|Reactome: R-HSA-983168 D521_1740 1d5a47bd8ad00c5db99c8244eb34e8a5 280 Pfam PF13371 Tetratricopeptide repeat 199 270 3.2E-20 T 14-10-2018 D521_0420 c5bd8ebd03d3a0343bfc629f8fbc45f0 321 Pfam PF03595 Voltage-dependent anion channel 14 312 4.0E-33 T 14-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 D521_0420 c5bd8ebd03d3a0343bfc629f8fbc45f0 321 Gene3D G3DSA:1.50.10.150 9 321 4.8E-60 T 14-10-2018 IPR038665 Voltage-dependent anion channel superfamily D521_1281 767c405a8ed6b696e651d8b9d8dd7a74 322 Pfam PF13280 WYL domain 144 319 2.9E-38 T 14-10-2018 IPR026881 WYL domain D521_0364 a2f9532d35b8dfbd1157850a63d22bcc 79 ProDom PD056452 UNCHARACTERIZED BACTERIA SIMILAR YPEB CYTOPLASMIC VCA0163 PRODUCT STM2426 GENE YPO2988 14 69 2.0E-18 T 14-10-2018 IPR024530 Putative quorum-sensing-regulated virulence factor D521_0364 a2f9532d35b8dfbd1157850a63d22bcc 79 Pfam PF12843 Putative quorum-sensing-regulated virulence factor 2 67 4.4E-30 T 14-10-2018 IPR024530 Putative quorum-sensing-regulated virulence factor D521_1193 0c041442ab795162ca4664df40c844c7 185 Pfam PF11748 Protein of unknown function (DUF3306) 4 112 6.1E-30 T 14-10-2018 IPR021735 Protein of unknown function DUF3306 D521_2041 0fd5c1cad5200e39bce0fb8f8567063c 171 SUPERFAMILY SSF50800 3 160 5.75E-16 T 14-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily D521_2041 0fd5c1cad5200e39bce0fb8f8567063c 171 Gene3D G3DSA:2.40.33.20 6 169 1.0E-10 T 14-10-2018 D521_0781 14703b3f41bd9aef8f70290b0aac685a 152 Pfam PF13664 Domain of unknown function (DUF4149) 9 107 1.9E-16 T 14-10-2018 IPR025423 Domain of unknown function DUF4149 D521_1094 8fb67e830248badd5479c7b7a43fd338 103 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 38 98 1.3E-16 T 14-10-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system D521_1552 ff36cfe50ee1a7cec3ed0a5a71561009 123 Pfam PF04134 Protein of unknown function, DUF393 2 108 2.7E-22 T 14-10-2018 IPR007263 Protein of unknown function DUF393 D521_0617 f6edd3fd5ac79024cd1a41f7e6601976 138 Pfam PF01850 PIN domain 2 122 7.9E-12 T 14-10-2018 IPR002716 PIN domain D521_0617 f6edd3fd5ac79024cd1a41f7e6601976 138 Gene3D G3DSA:3.40.50.1010 1 138 2.5E-35 T 14-10-2018 D521_0617 f6edd3fd5ac79024cd1a41f7e6601976 138 SUPERFAMILY SSF88723 1 137 3.08E-23 T 14-10-2018 IPR029060 PIN-like domain superfamily D521_1904 03bab10d77ce80ad4565f192d360c638 190 Gene3D G3DSA:3.40.50.1000 8 188 1.1E-57 T 14-10-2018 IPR023214 HAD superfamily D521_1904 03bab10d77ce80ad4565f192d360c638 190 SUPERFAMILY SSF56784 23 182 4.65E-40 T 14-10-2018 IPR036412 HAD-like superfamily D521_1904 03bab10d77ce80ad4565f192d360c638 190 Pfam PF08282 haloacid dehalogenase-like hydrolase 102 161 8.2E-11 T 14-10-2018 D521_1904 03bab10d77ce80ad4565f192d360c638 190 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 26 179 6.8E-51 T 14-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 D521_1904 03bab10d77ce80ad4565f192d360c638 190 PIRSF PIRSF006118 14 189 4.8E-65 T 14-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 D521_1963 d04a3dffffd9ecc404f6d2126db38cba 102 Gene3D G3DSA:3.40.30.10 3 102 1.9E-29 T 14-10-2018 D521_1963 d04a3dffffd9ecc404f6d2126db38cba 102 SUPERFAMILY SSF52833 3 101 4.25E-27 T 14-10-2018 IPR036249 Thioredoxin-like superfamily D521_1365 9c7a7527dd5a3abb82bc21341d168c47 412 Pfam PF07690 Major Facilitator Superfamily 21 310 1.5E-33 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_1365 9c7a7527dd5a3abb82bc21341d168c47 412 SUPERFAMILY SSF103473 9 401 4.71E-57 T 14-10-2018 IPR036259 MFS transporter superfamily D521_1365 9c7a7527dd5a3abb82bc21341d168c47 412 Gene3D G3DSA:1.20.1250.20 7 403 7.9E-48 T 14-10-2018 D521_1518 30c5937003bd9d1dd97d937770dc7027 133 Pfam PF09945 Predicted membrane protein (DUF2177) 5 127 4.2E-41 T 14-10-2018 IPR018687 Protein of unknown function DUF2177, membrane D521_0097 c1b2ab66a8fe438e24a5b66926664f22 160 Pfam PF02470 MlaD protein 39 116 2.1E-22 T 14-10-2018 IPR003399 Mce/MlaD D521_0097 c1b2ab66a8fe438e24a5b66926664f22 160 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 3 147 5.8E-61 T 14-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 D521_0874 7900c290f7e584f62d121b0aa55792b3 93 Pfam PF13997 YqjK-like protein 15 87 2.7E-17 T 14-10-2018 IPR025612 YqjK-like protein D521_0894 3090bcd94d908724f30c6cc81a04f725 410 Gene3D G3DSA:1.20.1250.20 4 404 4.7E-39 T 14-10-2018 D521_0894 3090bcd94d908724f30c6cc81a04f725 410 SUPERFAMILY SSF103473 13 400 4.32E-48 T 14-10-2018 IPR036259 MFS transporter superfamily D521_0894 3090bcd94d908724f30c6cc81a04f725 410 Pfam PF07690 Major Facilitator Superfamily 18 326 2.9E-20 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_2049 47b427af67bd8992b1ce83b9b18c24e9 171 Pfam PF06210 Protein of unknown function (DUF1003) 57 150 9.8E-36 T 14-10-2018 IPR010406 Protein of unknown function DUF1003 D521_1329 e074451a1b0fb703d38b2da805290965 330 Pfam PF03601 Conserved hypothetical protein 698 10 310 7.1E-68 T 14-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 D521_1256 b0b4bc66c7975b6c9793ad1edf566871 275 Pfam PF01148 Cytidylyltransferase family 3 271 1.6E-57 T 14-10-2018 D521_1256 b0b4bc66c7975b6c9793ad1edf566871 275 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 233 259 - T 14-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 D521_1831 6a84f9745eecc5d017258bdabdd70cdc 191 Pfam PF11086 Protein of unknown function (DUF2878) 17 173 6.1E-40 T 14-10-2018 IPR021306 Protein of unknown function DUF2878 D521_0404 48c64373b59d031caf982d497111425c 69 Pfam PF11127 Protein of unknown function (DUF2892) 6 60 7.2E-11 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 D521_0479 4167c6e1cf702f8a8bd74dcade35f8e6 259 Pfam PF00535 Glycosyl transferase family 2 5 126 2.3E-18 T 14-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 D521_0479 4167c6e1cf702f8a8bd74dcade35f8e6 259 SUPERFAMILY SSF53448 1 146 2.7E-29 T 14-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases D521_1991 b48fa2f8c2da6b5d5afb0d22457af1bf 136 Pfam PF07681 DoxX 9 89 2.4E-19 T 14-10-2018 IPR032808 DoxX family D521_0358 3233ee2aca614806c9b662a9b4c00da4 70 Pfam PF11127 Protein of unknown function (DUF2892) 1 61 2.4E-21 T 14-10-2018 IPR021309 Protein of unknown function DUF2892 D521_0015 95065eadabc87f2d8a97d229b6fd3a86 164 Pfam PF03899 ATP synthase I chain 48 151 3.0E-18 T 14-10-2018 IPR005598 ATP synthase protein I D521_0872 152855b213592e8156375d2e58c04bd6 111 Pfam PF05957 Bacterial protein of unknown function (DUF883) 19 111 2.0E-26 T 14-10-2018 IPR010279 Inner membrane protein YqjD/ElaB GO:0043022 D521_0729 ef2e61b75dd5754a3eb63d9d71bfbd69 161 Pfam PF06271 RDD family 10 145 7.5E-10 T 14-10-2018 IPR010432 RDD D521_0904 c8b60d5c589b1bb40d47e8deb83384f3 114 Gene3D G3DSA:1.10.760.10 19 109 1.4E-20 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0904 c8b60d5c589b1bb40d47e8deb83384f3 114 SUPERFAMILY SSF46626 32 109 2.54E-19 T 14-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 D521_0904 c8b60d5c589b1bb40d47e8deb83384f3 114 Pfam PF00034 Cytochrome c 22 106 5.0E-10 T 14-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 D521_1845 2ee144a195b7efae51a3d1d3d766213b 309 Pfam PF03547 Membrane transport protein 4 136 1.8E-10 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 D521_1845 2ee144a195b7efae51a3d1d3d766213b 309 Pfam PF03547 Membrane transport protein 148 302 2.5E-20 T 14-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 D521_0666 cc90bd89f8b11ada14a60f04e54d1c1f 114 ProDom PD394905 PM1122 UNCHARACTERIZED 15 100 1.0E-15 T 14-10-2018 D521_0761 394ca29e665d9a2d3f47812df8fe9c6e 175 PIRSF PIRSF032131 1 172 1.7E-39 T 14-10-2018 IPR009562 Protein of unknown function DUF1178 D521_0761 394ca29e665d9a2d3f47812df8fe9c6e 175 Pfam PF06676 Protein of unknown function (DUF1178) 1 168 5.0E-50 T 14-10-2018 IPR009562 Protein of unknown function DUF1178 D521_0369 e2d4478423d8027b929ede3326e9dd04 400 SUPERFAMILY SSF103473 1 393 1.83E-39 T 14-10-2018 IPR036259 MFS transporter superfamily D521_0369 e2d4478423d8027b929ede3326e9dd04 400 Pfam PF07690 Major Facilitator Superfamily 14 252 1.3E-14 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_0369 e2d4478423d8027b929ede3326e9dd04 400 Pfam PF07690 Major Facilitator Superfamily 258 393 8.1E-12 T 14-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 D521_0369 e2d4478423d8027b929ede3326e9dd04 400 Gene3D G3DSA:1.20.1250.20 9 390 1.5E-34 T 14-10-2018 D521_1852 05cd2781f6f6bec462ab2bef89af96fe 420 Pfam PF07399 Putative Na+/H+ antiporter 7 420 1.0E-172 T 14-10-2018 IPR009978 Putative Na+/H+ antiporter D521_0540 61c78bad201393320a46ef0ccf7b712b 499 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 439 5.2E-140 T 14-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane D521_0578 892a23c590403e8dd7e3dff7a32e68b3 108 Gene3D G3DSA:1.10.1660.10 16 108 6.0E-27 T 14-10-2018 D521_0578 892a23c590403e8dd7e3dff7a32e68b3 108 Pfam PF13591 MerR HTH family regulatory protein 24 102 1.3E-19 T 14-10-2018 D521_1470 6b3a9d472140dbdbf54f6dc361b57b34 145 Gene3D G3DSA:2.60.40.10 47 145 6.9E-5 T 14-10-2018 IPR013783 Immunoglobulin-like fold D521_0416 8e7b6d5332de262010fb8602be637569 384 Pfam PF05940 NnrS protein 7 378 3.8E-93 T 14-10-2018 IPR010266 NnrS D521_0378 be7b819f9f173bd3e45636538a978b8f 179 Pfam PF11136 Protein of unknown function (DUF2889) 12 134 1.2E-43 T 14-10-2018 IPR021312 Protein of unknown function DUF2889 D521_1274 074cc2467f78aab8ba3d09b177671e8c 1110 Pfam PF04465 Protein of unknown function (DUF499) 298 941 1.9E-32 T 14-10-2018 IPR007555 Protein of unknown function DUF499 D521_1358 28db6d706bb36071b629b331b0ecce62 143 Pfam PF08897 Domain of unknown function (DUF1841) 8 140 8.0E-59 T 14-10-2018 IPR014993 Protein of unknown function DUF1841 D521_1501 78f4a8609fc4a314a6eac1997cacc448 173 Pfam PF02417 Chromate transporter 6 169 1.5E-28 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 D521_1976 88689b3b93843c91176dbd65978cafdb 105 Pfam PF08895 Domain of unknown function (DUF1840) 1 103 9.7E-28 T 14-10-2018 IPR014991 Protein of unknown function DUF1840 D521_1560 f23d76f6b5b91eb8e20c78a917a9d9e7 292 Pfam PF13557 Putative MetA-pathway of phenol degradation 52 287 5.6E-12 T 14-10-2018 IPR025737 MetA-pathway of phenol degradation, putative D521_0009 352846b6efa548f24107febb56c52625 306 Pfam PF02653 Branched-chain amino acid transport system / permease component 17 294 4.9E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 D521_0811 ec652a15bc933b8da4009fb0087bc196 188 Pfam PF02417 Chromate transporter 16 175 1.3E-30 T 14-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 D521_0901 eade25b58e0bedb8fff01020741e2c68 391 Pfam PF05762 VWA domain containing CoxE-like protein 186 274 2.3E-10 T 14-10-2018 IPR008912 Uncharacterised protein family CoxE-like D521_0946 75cad2bcf503e973c0c26a8324488657 240 Pfam PF01435 Peptidase family M48 38 219 1.8E-34 T 14-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 D521_1793 491800a3fc62900c0e9e6a95fff3f7fb 311 Pfam PF02653 Branched-chain amino acid transport system / permease component 26 289 5.4E-31 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 D521_0330 6109d94bc82e769040610109397428c7 342 Pfam PF01699 Sodium/calcium exchanger protein 198 340 2.2E-9 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 D521_0330 6109d94bc82e769040610109397428c7 342 Pfam PF01699 Sodium/calcium exchanger protein 11 166 1.9E-15 T 14-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 D521_1304 94f35eb0a1c7d1c018a8875b8a77f43a 229 Gene3D G3DSA:1.10.10.10 19 117 1.5E-5 T 14-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily D521_0854 1d9d2a1946dd99acc6e818af6731e9cc 381 Gene3D G3DSA:3.30.310.170 262 381 4.8E-11 T 14-10-2018 D521_0854 1d9d2a1946dd99acc6e818af6731e9cc 381 Pfam PF06804 NlpB/DapX lipoprotein 45 374 5.0E-40 T 14-10-2018 IPR010653 NlpB/DapX lipoprotein D521_1097 2799f36ea57ad8e6d3a9196d8cf4b15d 480 Pfam PF13391 HNH endonuclease 381 433 2.6E-7 T 14-10-2018 IPR003615 HNH nuclease D521_1625 0723c6534e5ca2b7d383b1eac7dc36e3 493 Pfam PF02470 MlaD protein 15 106 9.4E-13 T 14-10-2018 IPR003399 Mce/MlaD D521_1625 0723c6534e5ca2b7d383b1eac7dc36e3 493 Pfam PF02470 MlaD protein 273 379 1.7E-15 T 14-10-2018 IPR003399 Mce/MlaD D521_0690 13e9575d1861c8dbfbe1620a50837e74 190 Pfam PF09361 Phasin protein 8 107 1.2E-10 T 14-10-2018 IPR018968 Phasin D521_1371 dbb024cadd7aa6d2166ad58327068ab1 131 Pfam PF10003 Integral membrane protein (DUF2244) 1 128 8.3E-30 T 14-10-2018 IPR019253 Protein of unknown function DUF2244, transmembrane D521_1734 18cbb15f1de3d7967ee539346da6b93e 101 Pfam PF06865 Protein of unknown function (DUF1255) 10 100 4.5E-27 T 14-10-2018 IPR009664 Pyrimidine/purine nucleoside phosphorylase KEGG: 00230+2.4.2.15|KEGG: 00240+2.4.2.4+2.4.2.3+2.4.2.2|KEGG: 00983+2.4.2.4+2.4.2.3|MetaCyc: PWY-5532|MetaCyc: PWY-7181 D521_1734 18cbb15f1de3d7967ee539346da6b93e 101 SUPERFAMILY SSF51182 10 100 2.79E-24 T 14-10-2018 IPR011051 RmlC-like cupin domain superfamily D521_1734 18cbb15f1de3d7967ee539346da6b93e 101 Gene3D G3DSA:2.60.120.10 1 101 1.8E-32 T 14-10-2018 IPR014710 RmlC-like jelly roll fold D521_2100 5eb2732512ef7b5e45a24c0ab0067299 88 SUPERFAMILY SSF143120 1 71 1.62E-5 T 14-10-2018 IPR036165 YefM-like superfamily D521_0795 064b0397519afb0bc4129ecb40970c4b 158 Pfam PF02308 MgtC family 14 139 1.5E-30 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 D521_0795 064b0397519afb0bc4129ecb40970c4b 158 PRINTS PR01837 MgtC/SapB protein signature 64 86 2.6E-28 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 D521_0795 064b0397519afb0bc4129ecb40970c4b 158 PRINTS PR01837 MgtC/SapB protein signature 36 54 2.6E-28 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 D521_0795 064b0397519afb0bc4129ecb40970c4b 158 PRINTS PR01837 MgtC/SapB protein signature 93 117 2.6E-28 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 D521_0795 064b0397519afb0bc4129ecb40970c4b 158 PRINTS PR01837 MgtC/SapB protein signature 17 36 2.6E-28 T 14-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 D521_1627 9ec67e14fa4e7a120ade0ebe3b39f5e1 208 Pfam PF04403 Paraquat-inducible protein A 47 198 3.9E-42 T 14-10-2018 IPR007498 Intermembrane transport protein PqiA-like D521_1794 c769808f69a85035253dd1f23cdf3b1c 286 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 273 2.5E-37 T 14-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 D521_1932 532b58bb33ef8ca151ae0c77e58057e6 70 Pfam PF11137 Protein of unknown function (DUF2909) 1 60 2.5E-25 T 14-10-2018 IPR021313 Protein of unknown function DUF2909 D521_1698 280e7c65bf4ea790abd2fd14cb338111 260 Pfam PF02535 ZIP Zinc transporter 93 256 8.8E-33 T 14-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085