locus-tag	class	description
VE98_C0001G0002	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
VE98_C0001G0006	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
VE98_C0001G0007	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VE98_C0001G0028	ENOG4105WG9	Conserved Protein
VE98_C0001G0029	ENOG4105FE9	pseudouridine synthase
VE98_C0001G0030	ENOG4107RSD	Multi-copper polyphenol oxidoreductase laccase
VE98_C0001G0034	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
VE98_C0001G0035	ENOG4105CJR	Integral membrane protein (MviN
VE98_C0001G0038	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
VE98_C0001G0041	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
VE98_C0001G0042	ENOG4105EGD	dinuclear metal center protein, YbgI family
VE98_C0001G0046	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
VE98_C0001G0060	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
VE98_C0001G0062	ENOG4105DR5	peptidase
VE98_C0001G0064	ENOG4108KGH	TRANSCRIPTIONal
VE98_C0001G0069	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
VE98_C0001G0070	ENOG4106H78	methyltransferase
VE98_C0001G0074	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
VE98_C0001G0075	ENOG4108JQC	penicillin-binding protein 1A
VE98_C0001G0077	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
VE98_C0001G0080	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
VE98_C0001G0081	ENOG4107QRG	dna polymerase iii
VE98_C0001G0084	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
VE98_C0001G0085	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
VE98_C0001G0087	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
VE98_C0001G0088	ENOG410805Y	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
VE98_C0001G0090	ENOG4108VZM	50s ribosomal protein L10
VE98_C0001G0091	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
VE98_C0001G0092	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
VE98_C0001G0101	ENOG4107WK9	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
VE98_C0001G0103	ENOG4105CUT	histidyl-tRNA synthetase
VE98_C0001G0108	ENOG4107YU2	histidine triad (hIT) protein
VE98_C0001G0110	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
VE98_C0001G0111	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
VE98_C0001G0112	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
VE98_C0001G0113	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
VE98_C0001G0114	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
VE98_C0001G0115	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
VE98_C0001G0118	ENOG41086YC	UPF0235 protein
VE98_C0001G0120	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
VE98_C0001G0122	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
VE98_C0001G0123	ENOG4105C3F	Signal peptidase i
VE98_C0001G0124	ENOG4105CE9	30S ribosomal protein S2
VE98_C0001G0125	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
VE98_C0001G0126	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
VE98_C0001G0127	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
VE98_C0001G0128	ENOG4105DZP	Membrane-associated zinc metalloprotease
VE98_C0001G0129	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
VE98_C0001G0130	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
VE98_C0001G0131	ENOG4105CRK	lysyL-tRNA synthetase
VE98_C0001G0134	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
VE98_C0001G0137	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
VE98_C0001G0141	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
VE98_C0001G0142	ENOG4105CAK	Cell division ATP-binding protein ftsE
VE98_C0001G0143	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
VE98_C0001G0146	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
VE98_C0001G0147	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
VE98_C0001G0150	ENOG4108V6E	Cell division protein mraZ
VE98_C0001G0151	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
VE98_C0001G0153	ENOG4105CJN	penicillin-binding protein
VE98_C0001G0154	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
VE98_C0001G0160	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
VE98_C0001G0161	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
VE98_C0001G0162	ENOG4105CNI	cell division protein FtsW
VE98_C0001G0163	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
VE98_C0001G0165	ENOG4105DFU	Cell wall formation (By similarity)
VE98_C0001G0168	ENOG4105C6E	dna polymerase iii
VE98_C0001G0169	ENOG4105CDU	Replicative dna helicase
VE98_C0001G0174	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
VE98_C0001G0176	ENOG4105C8N	cysteinyl-tRNA synthetase
VE98_C0001G0178	ENOG41082BM	Transcriptional regulator, arsr family
VE98_C0001G0181	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
VE98_C0001G0184	ENOG4105FEU	K -dependent Na -Ca exchanger
VE98_C0001G0185	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VE98_C0001G0193	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
VE98_C0001G0196	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
VE98_C0001G0199	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
VE98_C0001G0201	ENOG41067VY	50S ribosomal protein L32
VE98_C0001G0203	ENOG4105K5M	30s ribosomal protein S16
VE98_C0001G0204	ENOG4105VB6	UPF0109 protein
VE98_C0001G0206	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
VE98_C0001G0210	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
VE98_C0001G0211	ENOG4105C02	permease
VE98_C0001G0213	ENOG4105C79	DNA protecting protein DprA
VE98_C0001G0214	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
VE98_C0001G0216	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
VE98_C0001G0217	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
VE98_C0001G0219	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VE98_C0001G0223	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
VE98_C0001G0224	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
VE98_C0001G0225	ENOG41080IJ	Diacylglycerol kinase
VE98_C0001G0226	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
VE98_C0001G0227	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
VE98_C0001G0229	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
VE98_C0001G0239	ENOG4108JA2	transcriptioN-repair coupling factor
VE98_C0001G0244	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
VE98_C0001G0245	ENOG4105DZ1	carboxypeptidase
VE98_C0001G0246	ENOG4105C9M	aspartyl-trna synthetase
VE98_C0001G0249	ENOG41086CI	Bifunctional phosphoglucose phosphomannose isomerase
VE98_C0001G0250	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
VE98_C0001G0252	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
VE98_C0001G0256	ENOG4105D3R	alkyl hydroperoxide reductase
VE98_C0001G0260	ENOG4105C8Y	Acetylornithine aminotransferase
VE98_C0001G0262	ENOG4108KMV	Glycosyl transferase (Group 1
VE98_C0001G0263	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
VE98_C0001G0271	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
VE98_C0001G0275	ENOG4105K46	50S ribosomal protein l27
VE98_C0001G0276	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
VE98_C0001G0277	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
VE98_C0001G0280	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
VE98_C0001G0282	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
VE98_C0001G0287	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
VE98_C0001G0290	ENOG4107RBB	ABC transporter, permease
VE98_C0001G0291	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
VE98_C0001G0293	ENOG4105WDJ	50S ribosomal protein L33
VE98_C0001G0294	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
VE98_C0001G0296	ENOG4108UJD	30S ribosomal protein S9
VE98_C0001G0297	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
VE98_C0001G0298	ENOG4108ZT0	50S ribosomal protein l17
VE98_C0001G0299	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VE98_C0001G0300	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
VE98_C0001G0301	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
VE98_C0001G0302	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
VE98_C0001G0303	ENOG41067V7	50S ribosomal protein L36
VE98_C0001G0304	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
VE98_C0001G0305	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
VE98_C0001G0306	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
VE98_C0001G0308	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
VE98_C0001G0310	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
VE98_C0001G0311	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
VE98_C0001G0312	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
VE98_C0001G0313	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
VE98_C0001G0314	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
VE98_C0001G0315	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
VE98_C0001G0316	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
VE98_C0001G0317	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
VE98_C0001G0319	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
VE98_C0001G0320	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
VE98_C0001G0321	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
VE98_C0001G0322	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
VE98_C0001G0323	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
VE98_C0001G0325	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
VE98_C0001G0326	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
VE98_C0001G0327	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
VE98_C0001G0328	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
VE98_C0001G0331	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
VE98_C0001G0332	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
VE98_C0001G0334	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VE98_C0001G0335	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
VE98_C0001G0337	ENOG4105D0M	Protease HtpX homolog
VE98_C0001G0338	ENOG4108V0P	LemA family
VE98_C0001G0341	ENOG4105DEF	Extracellular solute-binding protein, family 5
VE98_C0001G0344	ENOG4109050	May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG)
VE98_C0001G0345	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
VE98_C0001G0346	ENOG41084BS	50S ribosomal protein L35
VE98_C0001G0347	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
VE98_C0001G0351	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
VE98_C0001G0353	ENOG4105D3Q	Sugar transferase
VE98_C0001G0354	ENOG4105DBI	uridine monophosphokinase
VE98_C0001G0365	ENOG4105C22	threonyL-tRNA synthetase
VE98_C0001G0367	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
VE98_C0001G0372	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
VE98_C0001G0374	ENOG4105CEU	Arginine dihydrolase
VE98_C0001G0375	ENOG4105C75	arginyL-tRNA synthetase
VE98_C0001G0376	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
VE98_C0001G0385	ENOG4105PNM	synthesis protein
VE98_C0001G0386	ENOG4105C0P	Mg chelatase subunit ChlI
VE98_C0001G0394	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
VE98_C0001G0395	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
VE98_C0001G0401	ENOG4105C83	adenylosuccinate lyase
VE98_C0001G0407	ENOG41082DI	50s ribosomal protein l31
VE98_C0001G0408	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
VE98_C0001G0409	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
VE98_C0001G0410	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
VE98_C0001G0411	ENOG4105C34	Pseudouridine synthase
VE98_C0001G0417	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
VE98_C0001G0426	ENOG41081VK	Ribonuclease
VE98_C0001G0428	ENOG4108Z4T	Peptidase M50
VE98_C0001G0429	ENOG4105VB9	50S ribosomal protein l28
VE98_C0001G0430	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
VE98_C0001G0435	ENOG4105VFU	Rna-binding protein
VE98_C0001G0438	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
VE98_C0001G0439	ENOG4105D2T	synthase
VE98_C0001G0441	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
VE98_C0001G0453	ENOG4105NCT	RNA Polymerase
VE98_C0001G0454	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
VE98_C0001G0457	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
VE98_C0001G0458	ENOG4105C1V	Peptidase, M16
VE98_C0001G0459	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
VE98_C0001G0462	ENOG4105K8N	protein family UPF0079, ATPase
VE98_C0001G0463	ENOG41072GX	Peptidase M22 Glycoprotease
VE98_C0001G0469	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
VE98_C0001G0471	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
VE98_C0001G0475	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
VE98_C0001G0478	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
VE98_C0001G0480	ENOG41067VN	Glutaredoxin
VE98_C0001G0481	ENOG4105D82	Glutamate dehydrogenase
VE98_C0001G0482	ENOG4105C3M	thioredoxin reductase
VE98_C0001G0486	ENOG4105K70	DNA-binding protein
VE98_C0001G0487	ENOG4108Z08	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
VE98_C0001G0489	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
VE98_C0001G0490	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
VE98_C0001G0494	ENOG4105C3J	Cysteine desulfurase
VE98_C0001G0498	ENOG4105ESV	Glycosyl transferase, family 4
VE98_C0001G0501	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
VE98_C0001G0502	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
VE98_C0001G0505	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
VE98_C0001G0506	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
VE98_C0001G0507	ENOG4105CDY	transcriptional regulatory protein
VE98_C0001G0516	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
VE98_C0001G0517	ENOG4108VPT	UPF0234 protein
VE98_C0001G0519	ENOG4105CNU	cell division protein FtsK
VE98_C0001G0524	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
VE98_C0001G0525	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
VE98_C0001G0526	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
VE98_C0001G0528	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
VE98_C0001G0530	ENOG4107RBI	VanW family
VE98_C0001G0532	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
VE98_C0001G0533	ENOG4108TJN	glycosyl transferase group 1
VE98_C0001G0536	ENOG4108TJN	glycosyl transferase group 1
VE98_C0001G0542	ENOG4105VG0	50S ribosomal protein l34
VE98_C0001G0543	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
VE98_C0001G0544	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
VE98_C0001G0545	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
VE98_C0001G0546	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
VE98_C0001G0548	ENOG4105C2M	dna polymerase I
VE98_C0001G0550	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
VE98_C0001G0552	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
VE98_C0001G0553	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
VE98_C0001G0555	ENOG4107QHF	type ii secretion system protein e
VE98_C0001G0564	ENOG4108Z6B	deaminase
VE98_C0001G0568	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
VE98_C0001G0571	ENOG4105MJ2	Competence protein
VE98_C0001G0572	ENOG4107QKV	phosphomannomutase
VE98_C0001G0573	ENOG4105C31	Tryptophanyl-tRNA synthetase
VE98_C0001G0577	ENOG4105C8T	Leucyl-tRNA synthetase
VE98_C0001G0579	ENOG4105C0B	DNA polymerase III (alpha subunit)
VE98_C0001G0581	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
VE98_C0001G0582	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
VE98_C0001G0583	ENOG4105VFF	UPF0102 protein
VE98_C0001G0584	ENOG4105CHV	Transcription elongation factor NusA
VE98_C0001G0585	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
VE98_C0001G0586	ENOG4105CTP	PilT protein domain protein
VE98_C0001G0591	ENOG4105C3G	gtp-binding protein
VE98_C0001G0592	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
VE98_C0001G0593	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
VE98_C0001G0594	ENOG4108UUM	single-stranded DNA-binding protein
VE98_C0001G0595	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)