locus-tag	class	description
US01_C0001G0003	ENOG4106855	Competence protein
US01_C0001G0004	ENOG4108VAU	general secretion pathway protein G
US01_C0001G0007	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
US01_C0001G0008	ENOG4105E4C	Lytic transglycosylase catalytic
US01_C0001G0009	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
US01_C0001G0012	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
US01_C0001G0015	ENOG4105CHW	UPF0052 protein
US01_C0001G0017	ENOG41073R8	VanW family
US01_C0001G0031	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
US01_C0001G0032	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
US01_C0001G0033	ENOG4105VG0	50S ribosomal protein l34
US01_C0001G0036	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
US01_C0001G0038	ENOG4105CVJ	phosphoglycerate mutase
US01_C0001G0040	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
US01_C0001G0042	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
US01_C0001G0056	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
US01_C0001G0058	ENOG4107TRG	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
US01_C0001G0059	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
US01_C0001G0060	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
US01_C0001G0062	ENOG4105CTB	Polyprenyl synthetase
US01_C0001G0076	ENOG4105EY8	ABC transporter
US01_C0001G0078	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
US01_C0001G0087	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
US01_C0001G0088	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
US01_C0001G0093	ENOG4105BZA	Phosphoglycerate kinase
US01_C0001G0094	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
US01_C0001G0095	ENOG4105D3Q	Sugar transferase
US01_C0001G0099	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
US01_C0001G0114	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
US01_C0001G0116	ENOG4105CJR	Integral membrane protein (MviN
US01_C0001G0121	ENOG4105VRS	hydrolase family 18
US01_C0001G0127	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
US01_C0001G0129	ENOG4105BZ4	penicillin-binding protein
US01_C0001G0131	ENOG4105CAT	Cytidine monophosphate kinase
US01_C0001G0133	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
US01_C0001G0135	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
US01_C0001G0136	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
US01_C0001G0138	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
US01_C0001G0139	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
US01_C0001G0144	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
US01_C0001G0145	ENOG4105CPF	Cell wall formation (By similarity)
US01_C0001G0146	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
US01_C0001G0147	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
US01_C0001G0149	ENOG4105C2M	dna polymerase I
US01_C0001G0150	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
US01_C0001G0152	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
US01_C0001G0153	ENOG410839E	ATP synthase, F0 subunit c
US01_C0001G0155	ENOG4106F7A	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
US01_C0001G0156	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
US01_C0001G0157	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
US01_C0001G0158	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
US01_C0001G0160	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
US01_C0001G0162	ENOG4105CFG	Acts as a chaperone (By similarity)
US01_C0001G0163	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
US01_C0001G0164	ENOG4105CHV	Transcription elongation factor NusA
US01_C0001G0165	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
US01_C0001G0166	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
US01_C0001G0168	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
US01_C0001G0170	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
US01_C0001G0173	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
US01_C0001G0175	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
US01_C0001G0178	ENOG4108YZG	isomerase
US01_C0001G0179	ENOG4105DJV	ribulose-phosphate 3-epimerase
US01_C0001G0181	ENOG4107UH8	sugar kinase
US01_C0001G0183	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
US01_C0001G0184	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
US01_C0001G0185	ENOG4105CN5	Metallo-Beta-Lactamase
US01_C0001G0186	ENOG4105CNU	cell division protein FtsK
US01_C0001G0187	ENOG4105MJ2	Competence protein
US01_C0001G0191	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
US01_C0001G0194	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
US01_C0001G0197	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
US01_C0001G0200	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
US01_C0001G0201	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
US01_C0001G0202	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
US01_C0001G0203	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
US01_C0001G0204	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
US01_C0001G0206	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
US01_C0001G0207	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
US01_C0001G0208	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
US01_C0001G0209	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
US01_C0001G0210	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
US01_C0001G0211	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
US01_C0001G0212	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
US01_C0001G0213	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
US01_C0001G0214	ENOG41084PQ	50s ribosomal protein l29
US01_C0001G0215	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
US01_C0001G0216	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
US01_C0001G0217	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
US01_C0001G0218	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
US01_C0001G0219	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
US01_C0001G0220	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
US01_C0001G0221	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
US01_C0001G0223	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
US01_C0001G0224	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
US01_C0001G0225	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
US01_C0001G0226	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
US01_C0001G0227	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
US01_C0001G0228	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
US01_C0001G0229	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
US01_C0001G0230	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
US01_C0001G0231	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
US01_C0001G0232	ENOG4108ZT0	50S ribosomal protein l17
US01_C0001G0233	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
US01_C0001G0234	ENOG4108UJD	30S ribosomal protein S9
US01_C0001G0239	ENOG41085FC	arsR family transcriptional regulator
US01_C0001G0241	ENOG4105DIW	FeS assembly protein SUFB
US01_C0001G0243	ENOG4105C9B	Cysteine desulfurase
US01_C0001G0244	ENOG4108UNV	SUF system FeS assembly protein, NifU family
US01_C0001G0246	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
US01_C0001G0247	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
US01_C0001G0250	ENOG4105BZU	Histidine kinase
US01_C0001G0251	ENOG4105VFU	Rna-binding protein
US01_C0001G0252	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
US01_C0001G0253	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
US01_C0001G0255	ENOG4105E09	nadh pyrophosphatase
US01_C0001G0259	ENOG4107SET	aldo keto reductase
US01_C0001G0260	ENOG4105VC4	domain protein
US01_C0001G0262	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
US01_C0001G0265	ENOG4107XGZ	Hydrolase
US01_C0001G0272	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
US01_C0001G0273	ENOG4105CAK	Cell division ATP-binding protein ftsE
US01_C0001G0275	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
US01_C0001G0280	ENOG4107ZBH	radical SAM domain protein
US01_C0001G0281	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
US01_C0001G0289	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
US01_C0001G0292	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
US01_C0001G0293	ENOG4107RBB	ABC transporter, permease
US01_C0001G0296	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
US01_C0001G0297	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
US01_C0001G0302	ENOG4105C4R	Atp-dependent dna helicase
US01_C0001G0303	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
US01_C0001G0306	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
US01_C0001G0330	ENOG4105C5H	ABC transporter
US01_C0001G0336	ENOG4105Y3U	Transglycosylase-associated protein
US01_C0001G0343	ENOG4105VZ8	Transcriptional regulator
US01_C0001G0347	ENOG4105C1J	atp-dependent rna helicase
US01_C0001G0348	ENOG4105CYW	agmatinase
US01_C0001G0353	ENOG4105KVH	Transcriptional regulator
US01_C0001G0360	ENOG4105C19	ABC transporter
US01_C0001G0363	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
US01_C0001G0364	ENOG4105BZU	Histidine kinase
US01_C0001G0365	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
US01_C0001G0366	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
US01_C0001G0367	ENOG4105FE9	pseudouridine synthase
US01_C0001G0368	ENOG4108YZS	Had-superfamily hydrolase, subfamily ia, variant 1
US01_C0001G0369	ENOG4105CI3	gtp-binding protein typa
US01_C0001G0370	ENOG4105D1H	recombination factor protein RarA
US01_C0001G0383	ENOG41063C6	UPF0235 protein
US01_C0001G0385	ENOG4105EMN	RNA polymerase sigma factor
US01_C0001G0387	ENOG4105VYW	UPF0251 protein
US01_C0001G0392	ENOG4107QTF	adenylosuccinate lyase
US01_C0001G0393	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
US01_C0001G0394	ENOG4108RWN	rrna methyltransferase
US01_C0001G0396	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
US01_C0001G0407	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
US01_C0001G0410	ENOG4105C3M	thioredoxin reductase
US01_C0001G0413	ENOG4105ESV	Glycosyl transferase, family 4
US01_C0001G0417	ENOG4105F8V	Hydrolase, tatD family
US01_C0001G0418	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
US01_C0001G0423	ENOG4105C9M	aspartyl-trna synthetase
US01_C0001G0424	ENOG4105DZ1	carboxypeptidase
US01_C0001G0426	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
US01_C0001G0429	ENOG4105C6E	dna polymerase iii
US01_C0001G0431	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
US01_C0001G0432	ENOG4105EIE	fructose-bisphosphate aldolase
US01_C0001G0442	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
US01_C0001G0445	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
US01_C0001G0446	ENOG4105DZP	Membrane-associated zinc metalloprotease
US01_C0001G0448	ENOG4108R5T	secreted protein
US01_C0001G0450	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
US01_C0001G0451	ENOG4107WK9	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
US01_C0001G0452	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
US01_C0001G0453	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
US01_C0001G0454	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
US01_C0001G0455	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
US01_C0001G0459	ENOG4105C6N	Formate acetyltransferase
US01_C0001G0460	ENOG4105F1A	Pyruvate formate-lyase
US01_C0001G0462	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
US01_C0001G0464	ENOG4105CGK	Exodeoxyribonuclease III
US01_C0001G0466	ENOG4107TUY	Histidine kinase
US01_C0001G0469	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
US01_C0001G0476	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
US01_C0001G0478	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
US01_C0001G0479	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
US01_C0001G0483	ENOG4108RCF	TRANSCRIPTIONal
US01_C0001G0490	ENOG4105CKK	Glycosyl transferase, family 2
US01_C0001G0491	ENOG4106WTF	Glycosyl transferase, family 2
US01_C0001G0492	ENOG4105H63	Glycosyl transferase, family 2
US01_C0001G0493	ENOG4106WTF	Glycosyl transferase, family 2
US01_C0001G0495	ENOG4107R8N	Glycosyl transferase, family 2
US01_C0001G0499	ENOG4108TJN	glycosyl transferase group 1
US01_C0001G0501	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
US01_C0001G0508	ENOG4105CKK	Glycosyl transferase, family 2
US01_C0001G0520	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
US01_C0001G0526	ENOG4108IAJ	Nad-dependent epimerase dehydratase
US01_C0001G0529	ENOG4105CG5	Glycosyl transferase (Group 1
US01_C0001G0531	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
US01_C0001G0532	ENOG410852I	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
US01_C0001G0533	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
US01_C0001G0538	ENOG4105E2K	Glycosyl transferase (Group 1
US01_C0001G0540	ENOG4105CPK	Glycosyl transferase (Group 1
US01_C0001G0542	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
US01_C0001G0543	ENOG4105D3Q	Sugar transferase
US01_C0001G0545	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
US01_C0001G0548	ENOG4108V6E	Cell division protein mraZ
US01_C0001G0552	ENOG4105FA0	parb-like partition protein
US01_C0001G0553	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
US01_C0001G0554	ENOG4105C31	Tryptophanyl-tRNA synthetase
US01_C0001G0555	ENOG4105K46	50S ribosomal protein l27
US01_C0001G0556	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
US01_C0001G0557	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
US01_C0001G0558	ENOG4105CNI	cell division protein FtsW
US01_C0001G0559	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
US01_C0001G0560	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
US01_C0001G0561	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
US01_C0001G0563	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
US01_C0001G0564	ENOG4105CNI	cell division protein FtsW
US01_C0001G0565	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
US01_C0001G0566	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
US01_C0001G0567	ENOG4105D4A	Cell wall formation (By similarity)
US01_C0001G0568	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
US01_C0001G0569	ENOG4105C3F	Signal peptidase i
US01_C0001G0573	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
US01_C0001G0581	ENOG4105D0M	Protease HtpX homolog
US01_C0001G0582	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
US01_C0001G0583	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
US01_C0001G0584	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
US01_C0001G0585	ENOG4105C0B	DNA polymerase III (alpha subunit)
US01_C0001G0590	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
US01_C0001G0592	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
US01_C0001G0593	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
US01_C0001G0601	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
US01_C0001G0602	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
US01_C0001G0612	ENOG4107QKV	phosphomannomutase
US01_C0001G0613	ENOG41086CI	Bifunctional phosphoglucose phosphomannose isomerase
US01_C0001G0614	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
US01_C0001G0615	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
US01_C0001G0617	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
US01_C0001G0618	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
US01_C0001G0619	ENOG41082RQ	UPF0102 protein
US01_C0001G0627	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
US01_C0001G0628	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
US01_C0001G0635	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
US01_C0001G0636	ENOG4105C02	permease
US01_C0001G0650	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
US01_C0001G0651	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
US01_C0001G0655	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
US01_C0001G0657	ENOG4105C0P	Mg chelatase subunit ChlI
US01_C0001G0658	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
US01_C0001G0659	ENOG4105DFU	Cell wall formation (By similarity)
US01_C0001G0665	ENOG4108JJ7	ABC transporter
US01_C0001G0667	ENOG4107GJV	short-chain dehydrogenase reductase
US01_C0001G0668	ENOG4105C9U	ATP-dependent DNA helicase RecQ
US01_C0001G0671	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
US01_C0001G0673	ENOG4105CV8	reductase
US01_C0001G0682	ENOG4105KAV	tspo and mbr like protein
US01_C0001G0686	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
US01_C0001G0689	ENOG4105CA9	Pyruvate kinase
US01_C0001G0690	ENOG4105CVJ	phosphoglycerate mutase
US01_C0001G0697	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
US01_C0001G0699	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
US01_C0001G0701	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
US01_C0001G0702	ENOG41082T9	Membrane
US01_C0001G0704	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
US01_C0001G0717	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
US01_C0001G0725	ENOG4105CP7	Triose-phosphate isomerase
US01_C0001G0726	ENOG4105C4R	Atp-dependent dna helicase
US01_C0001G0727	ENOG4108TV1	Catalyzes the incorporation of amino acid(s) into the interchain peptide bridge of peptidoglycan, using aminoacyl-tRNA as amino acid donor (By similarity)
US01_C0001G0728	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
US01_C0001G0729	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
US01_C0001G0730	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
US01_C0001G0735	ENOG41084BS	50S ribosomal protein L35
US01_C0001G0736	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
US01_C0001G0738	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
US01_C0001G0739	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
US01_C0001G0741	ENOG4105BZ4	penicillin-binding protein
US01_C0001G0742	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
US01_C0001G0744	ENOG4105CB5	ATP-dependent DNA helicase recG
US01_C0001G0749	ENOG4105VB6	UPF0109 protein
US01_C0001G0750	ENOG4105K5M	30s ribosomal protein S16
US01_C0001G0751	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
US01_C0001G0752	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
US01_C0001G0765	ENOG4108VAU	general secretion pathway protein G
US01_C0001G0769	ENOG4105D7Q	type ii secretion system
US01_C0001G0770	ENOG4105CZX	twitching motility protein
US01_C0001G0771	ENOG4107QHF	type ii secretion system protein e
US01_C0001G0773	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
US01_C0001G0774	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
US01_C0001G0778	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
US01_C0001G0780	ENOG4105CDY	transcriptional regulatory protein
US01_C0001G0783	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
US01_C0001G0784	ENOG4105CE9	30S ribosomal protein S2
US01_C0001G0786	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
US01_C0001G0789	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
US01_C0001G0790	ENOG4105C34	Pseudouridine synthase
US01_C0001G0795	ENOG4105CDU	Replicative dna helicase
US01_C0001G0801	ENOG4105CUT	histidyl-tRNA synthetase
US01_C0001G0802	ENOG41082DI	50s ribosomal protein l31
US01_C0001G0803	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
US01_C0001G0805	ENOG41087BT	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
US01_C0001G0806	ENOG4107XMK	single-stranded DNA-binding protein
US01_C0001G0807	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
US01_C0001G0809	ENOG4105C3G	gtp-binding protein
US01_C0001G0815	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
US01_C0001G0816	ENOG410681U	heavy metal transport detoxification protein
US01_C0001G0820	ENOG4105W5Q	DNA repair protein (RadC
US01_C0001G0821	ENOG4105C8N	cysteinyl-tRNA synthetase
US01_C0001G0827	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
US01_C0001G0829	ENOG4107ZFB	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
US01_C0001G0830	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
US01_C0001G0832	ENOG41084X0	Dihydrofolate reductase
US01_C0001G0834	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
US01_C0001G0836	ENOG4108UK2	deaminase
US01_C0001G0837	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
US01_C0001G0838	ENOG4105C4K	Nad synthetase
US01_C0001G0841	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
US01_C0001G0842	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
US01_C0001G0843	ENOG4105C79	DNA protecting protein DprA
US01_C0001G0844	ENOG4105CJN	penicillin-binding protein
US01_C0001G0850	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
US01_C0001G0851	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
US01_C0001G0852	ENOG4105KDC	50s ribosomal protein l28
US01_C0001G0853	ENOG4108Z4T	Peptidase M50
US01_C0001G0862	ENOG41087NY	50S ribosomal protein L33
US01_C0001G0866	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
US01_C0001G0870	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
US01_C0001G0871	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
US01_C0001G0874	ENOG4105C22	threonyL-tRNA synthetase
US01_C0001G0876	ENOG4107R34	abc transporter permease protein
US01_C0001G0877	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
US01_C0001G0880	ENOG4108VZM	50s ribosomal protein L10
US01_C0001G0881	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
US01_C0001G0885	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
US01_C0001G0896	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
US01_C0001G0897	ENOG4105C1V	Peptidase, M16
US01_C0001G0901	ENOG4105C8T	Leucyl-tRNA synthetase