locus-tag	class	description
RGRSB_0002	COG0033	Phosphoglucomutase
RGRSB_0003	COG0193	aminoacyl-tRNA hydrolase activity
RGRSB_0008	COG0248	Ppx GppA phosphatase
RGRSB_0009	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RGRSB_0013	COG0799	negative regulation of ribosome biogenesis
RGRSB_0015	COG0542	response to heat
RGRSB_0016	COG1214	PFAM Peptidase M22, glycoprotease
RGRSB_0016	COG0456	acetyltransferase
RGRSB_0017	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RGRSB_0018	COG4581	dead DEAH box helicase
RGRSB_0019	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RGRSB_0024	COG2099	Precorrin-6x reductase
RGRSB_0031	COG0009	L-threonylcarbamoyladenylate synthase
RGRSB_0034	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
RGRSB_0037	COG0783	Belongs to the Dps family
RGRSB_0042	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RGRSB_0049	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RGRSB_0052	COG1132	(ABC) transporter
RGRSB_0054	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RGRSB_0054	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RGRSB_0056	COG0742	ribosomal rna small subunit methyltransferase
RGRSB_0057	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RGRSB_0058	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RGRSB_0060	COG0454	-acetyltransferase
RGRSB_0063	COG2890	protein-(glutamine-N5) methyltransferase activity
RGRSB_0064	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RGRSB_0068	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
RGRSB_0069	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RGRSB_0070	COG0793	Belongs to the peptidase S41A family
RGRSB_0072	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RGRSB_0073	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RGRSB_0073	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RGRSB_0075	COG0598	Magnesium transport protein CorA
RGRSB_0076	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RGRSB_0082	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RGRSB_0084	COG1122	ATPase activity
RGRSB_0091	COG0392	lysyltransferase activity
RGRSB_0092	COG0071	Belongs to the small heat shock protein (HSP20) family
RGRSB_0093	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RGRSB_0095	COG1473	amidohydrolase
RGRSB_0099	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RGRSB_0102	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
RGRSB_0103	COG1799	cell septum assembly
RGRSB_0104	COG0659	secondary active sulfate transmembrane transporter activity
RGRSB_0105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RGRSB_0109	COG0724	RNA recognition motif
RGRSB_0112	COG1012	belongs to the aldehyde dehydrogenase family
RGRSB_0114	COG0473	3-isopropylmalate dehydrogenase activity
RGRSB_0116	COG0366	Alpha amylase catalytic
RGRSB_0117	COG0569	domain protein
RGRSB_0118	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RGRSB_0119	COG2385	sporulation resulting in formation of a cellular spore
RGRSB_0119	COG2247	cell wall binding repeat
RGRSB_0124	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RGRSB_0125	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RGRSB_0126	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RGRSB_0128	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RGRSB_0132	COG1331	Highly conserved protein containing a thioredoxin domain
RGRSB_0136	COG5322	oxidoreductase activity
RGRSB_0138	COG0728	peptidoglycan biosynthetic process
RGRSB_0144	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RGRSB_0146	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
RGRSB_0147	COG3932	Exopolysaccharide synthesis, ExoD
RGRSB_0150	COG0723	plastoquinol--plastocyanin reductase activity
RGRSB_0151	COG0154	amidase activity
RGRSB_0154	COG0009	L-threonylcarbamoyladenylate synthase
RGRSB_0157	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RGRSB_0159	COG0180	Tryptophanyl-tRNA synthetase
RGRSB_0167	COG3338	carbonate dehydratase activity
RGRSB_0172	COG0488	(ABC) transporter
RGRSB_0174	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RGRSB_0175	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RGRSB_0176	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
RGRSB_0177	COG3118	belongs to the thioredoxin family
RGRSB_0178	COG0297	glycogen (starch) synthase activity
RGRSB_0179	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RGRSB_0180	COG2981	High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway
RGRSB_0182	COG0194	GDP metabolic process
RGRSB_0185	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
RGRSB_0186	COG1472	Belongs to the glycosyl hydrolase 3 family
RGRSB_0189	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
RGRSB_0195	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RGRSB_0196	COG1126	abc transporter atp-binding protein
RGRSB_0198	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
RGRSB_0199	COG0242	peptide deformylase activity
RGRSB_0201	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RGRSB_0203	COG0612	Peptidase, M16
RGRSB_0204	COG3937	granule-associated protein
RGRSB_0205	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RGRSB_0206	COG0631	protein serine/threonine phosphatase activity
RGRSB_0208	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RGRSB_0209	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RGRSB_0210	COG0564	pseudouridine synthase activity
RGRSB_0212	COG1012	belongs to the aldehyde dehydrogenase family
RGRSB_0213	COG0028	Belongs to the TPP enzyme family
RGRSB_0215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RGRSB_0216	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RGRSB_0217	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RGRSB_0218	COG2267	carboxylic ester hydrolase activity
RGRSB_0220	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RGRSB_0225	COG0483	inositol monophosphate 1-phosphatase activity
RGRSB_0228	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RGRSB_0229	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
RGRSB_0233	COG4555	ABC transporter
RGRSB_0234	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RGRSB_0237	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RGRSB_0238	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RGRSB_0241	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RGRSB_0248	COG0601	transmembrane transport
RGRSB_0252	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
RGRSB_0254	COG1196	nuclear chromosome segregation
RGRSB_0256	COG0857	belongs to the CobB CobQ family
RGRSB_0258	COG2226	methyltransferase
RGRSB_0259	COG0768	penicillin binding
RGRSB_0263	COG2208	phosphoserine phosphatase activity
RGRSB_0271	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RGRSB_0272	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RGRSB_0273	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RGRSB_0274	COG0725	ABC transporter, periplasmic molybdate-binding protein
RGRSB_0277	COG1376	ErfK ybiS ycfS ynhG family protein
RGRSB_0278	COG3659	wide pore channel activity
RGRSB_0281	COG0312	modulator of DNA gyrase
RGRSB_0282	COG0552	protein localization to endoplasmic reticulum
RGRSB_0285	COG0701	Predicted permease
RGRSB_0287	COG2082	Precorrin-8x methylmutase
RGRSB_0288	COG4597	amino acid ABC transporter
RGRSB_0289	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RGRSB_0297	COG4999	Histidine kinase
RGRSB_0297	COG3850	Histidine kinase
RGRSB_0297	COG3437	response regulator, receiver
RGRSB_0297	COG2205	protein histidine kinase activity
RGRSB_0300	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
RGRSB_0302	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RGRSB_0303	COG3239	Fatty acid desaturase
RGRSB_0306	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RGRSB_0312	COG0628	permease
RGRSB_0323	COG0045	succinate-CoA ligase (ADP-forming) activity
RGRSB_0325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RGRSB_0327	COG0517	IMP dehydrogenase activity
RGRSB_0327	COG1994	Peptidase M50
RGRSB_0328	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RGRSB_0333	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RGRSB_0335	COG0195	Participates in both transcription termination and antitermination
RGRSB_0338	COG2319	Wd-40 repeat
RGRSB_0338	COG1672	PFAM Archaeal ATPase
RGRSB_0339	COG2046	Belongs to the sulfate adenylyltransferase family
RGRSB_0340	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RGRSB_0341	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RGRSB_0343	COG0163	prenyltransferase activity
RGRSB_0345	COG0395	ABC-type sugar transport system, permease component
RGRSB_0346	COG1175	transmembrane transport
RGRSB_0347	COG1653	transport
RGRSB_0348	COG3842	ATPase activity
RGRSB_0352	COG0646	methionine synthase
RGRSB_0352	COG1410	methionine synthase
RGRSB_0356	COG0084	hydrolase, TatD family'
RGRSB_0357	COG0085	RNA polymerase activity
RGRSB_0363	COG0778	Nitroreductase
RGRSB_0364	COG0445	tRNA wobble uridine modification
RGRSB_0366	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RGRSB_0370	COG0515	serine threonine protein kinase
RGRSB_0371	COG0372	Belongs to the citrate synthase family
RGRSB_0374	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RGRSB_0376	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RGRSB_0378	COG0475	glutathione-regulated potassium exporter activity
RGRSB_0379	COG0860	N-Acetylmuramoyl-L-alanine amidase
RGRSB_0382	COG0142	geranyltranstransferase activity
RGRSB_0389	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RGRSB_0391	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RGRSB_0392	COG5002	protein histidine kinase activity
RGRSB_0395	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
RGRSB_0395	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
RGRSB_0404	COG1218	3'(2'),5'-bisphosphate nucleotidase
RGRSB_0420	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RGRSB_0425	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RGRSB_0428	COG1429	ligase activity, forming nitrogen-metal bonds
RGRSB_0433	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RGRSB_0435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RGRSB_0436	COG0047	phosphoribosylformylglycinamidine synthase activity
RGRSB_0437	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RGRSB_0441	COG0681	Belongs to the peptidase S26 family
RGRSB_0448	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
RGRSB_0449	COG0484	heat shock protein binding
RGRSB_0450	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RGRSB_0451	COG0023	Translation Initiation Factor
RGRSB_0453	COG0402	S-adenosylhomocysteine deaminase activity
RGRSB_0455	COG0326	Molecular chaperone. Has ATPase activity
RGRSB_0457	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RGRSB_0468	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RGRSB_0477	COG0201	protein transport
RGRSB_0478	COG0563	adenylate kinase activity
RGRSB_0479	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RGRSB_0480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RGRSB_0483	COG0202	RNA polymerase activity
RGRSB_0492	COG0587	DNA-directed DNA polymerase activity
RGRSB_0493	COG0175	sulfate reduction
RGRSB_0494	COG0528	UMP kinase activity
RGRSB_0500	COG1473	amidohydrolase
RGRSB_0503	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
RGRSB_0505	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
RGRSB_0506	COG2385	sporulation resulting in formation of a cellular spore
RGRSB_0507	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RGRSB_0509	COG2166	iron-sulfur cluster assembly
RGRSB_0511	COG1104	cysteine desulfurase activity
RGRSB_0517	COG0573	inorganic phosphate transmembrane transporter activity
RGRSB_0518	COG0581	inorganic phosphate transmembrane transporter activity
RGRSB_0519	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RGRSB_0520	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RGRSB_0524	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
RGRSB_0525	COG0745	RESPONSE REGULATOR receiver
RGRSB_0526	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
RGRSB_0532	COG0443	Heat shock 70 kDa protein
RGRSB_0534	COG0438	transferase activity, transferring glycosyl groups
RGRSB_0538	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RGRSB_0539	COG2239	Acts as a magnesium transporter
RGRSB_0540	COG0440	acetolactate synthase activity
RGRSB_0544	COG0179	Fumarylacetoacetate (FAA) hydrolase
RGRSB_0550	COG1088	dTDP-glucose 4,6-dehydratase activity
RGRSB_0553	COG2091	lysine biosynthetic process via aminoadipic acid
RGRSB_0555	COG0540	Belongs to the ATCase OTCase family
RGRSB_0558	COG1252	NADH dehydrogenase
RGRSB_0562	COG0371	Dehydrogenase
RGRSB_0563	COG0589	response to stress
RGRSB_0565	COG3794	PFAM blue (type 1) copper domain protein
RGRSB_0566	COG0436	Aminotransferase
RGRSB_0569	COG0575	Belongs to the CDS family
RGRSB_0571	COG0343	queuine tRNA-ribosyltransferase activity
RGRSB_0573	COG3659	wide pore channel activity
RGRSB_0574	COG0704	Plays a role in the regulation of phosphate uptake
RGRSB_0575	COG0024	Methionine aminopeptidase
RGRSB_0579	COG3956	TIGRFAM MazG family protein
RGRSB_0580	COG0681	Belongs to the peptidase S26 family
RGRSB_0583	COG0429	hydrolase of the alpha beta-hydrolase fold
RGRSB_0584	COG0745	RESPONSE REGULATOR receiver
RGRSB_0591	COG2205	protein histidine kinase activity
RGRSB_0599	COG0525	valine-tRNA ligase activity
RGRSB_0601	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RGRSB_0604	COG2010	Cytochrome c
RGRSB_0606	COG1215	transferase activity, transferring glycosyl groups
RGRSB_0607	COG0300	oxidoreductase activity
RGRSB_0607	COG3000	fatty acid hydroxylase
RGRSB_0608	COG1122	ATPase activity
RGRSB_0611	COG0811	peptide transport
RGRSB_0612	COG0848	biopolymer transport protein
RGRSB_0619	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RGRSB_0620	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RGRSB_0620	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RGRSB_0622	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RGRSB_0624	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RGRSB_0633	COG1615	UPF0182 protein
RGRSB_0640	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RGRSB_0645	COG2192	nodulation
RGRSB_0647	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RGRSB_0649	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
RGRSB_0654	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RGRSB_0655	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
RGRSB_0656	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RGRSB_0657	COG0739	heme binding
RGRSB_0659	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
RGRSB_0660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RGRSB_0661	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RGRSB_0663	COG0740	serine-type endopeptidase activity
RGRSB_0666	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RGRSB_0671	COG0708	Exodeoxyribonuclease III
RGRSB_0672	COG0793	Belongs to the peptidase S41A family
RGRSB_0674	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RGRSB_0674	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RGRSB_0675	COG1562	ergosterol biosynthetic process
RGRSB_0682	COG0006	proline dipeptidase activity
RGRSB_0685	COG0300	oxidoreductase activity
RGRSB_0687	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
RGRSB_0687	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
RGRSB_0688	COG2363	Small membrane protein
RGRSB_0691	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RGRSB_0695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RGRSB_0697	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RGRSB_0698	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RGRSB_0701	COG1595	DNA-templated transcription, initiation
RGRSB_0704	COG1022	Amp-dependent synthetase and ligase
RGRSB_0708	COG0004	ammonium transporteR
RGRSB_0709	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RGRSB_0709	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RGRSB_0711	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RGRSB_0712	COG0557	exoribonuclease II activity
RGRSB_0716	COG0181	hydroxymethylbilane synthase activity
RGRSB_0717	COG0408	coproporphyrinogen oxidase activity
RGRSB_0718	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
RGRSB_0720	COG0352	thiamine-phosphate diphosphorylase activity
RGRSB_0725	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
RGRSB_0727	COG0436	Aminotransferase
RGRSB_0730	COG0601	transmembrane transport
RGRSB_0736	COG0588	phosphoglycerate mutase activity
RGRSB_0737	COG0066	3-isopropylmalate dehydratase activity
RGRSB_0738	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RGRSB_0741	COG0681	Belongs to the peptidase S26 family
RGRSB_0747	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
RGRSB_0748	COG2310	stress, protein
RGRSB_0750	COG0670	Belongs to the BI1 family
RGRSB_0759	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RGRSB_0762	COG0484	heat shock protein binding
RGRSB_0764	COG1959	2 iron, 2 sulfur cluster binding
RGRSB_0765	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
RGRSB_0766	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RGRSB_0767	COG0776	regulation of translation
RGRSB_0770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RGRSB_0777	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RGRSB_0782	COG1619	proteins homologs of microcin C7 resistance protein MccF
RGRSB_0784	COG0463	Glycosyl transferase, family 2
RGRSB_0790	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RGRSB_0794	COG0805	protein transport
RGRSB_0798	COG0587	DNA-directed DNA polymerase activity
RGRSB_0805	COG1160	GTP binding
RGRSB_0817	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RGRSB_0818	COG2205	protein histidine kinase activity
RGRSB_0819	COG2205	protein histidine kinase activity
RGRSB_0819	COG0784	Response regulator, receiver
RGRSB_0821	COG0116	Belongs to the methyltransferase superfamily
RGRSB_0822	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RGRSB_0823	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RGRSB_0829	COG1253	flavin adenine dinucleotide binding
RGRSB_0832	COG1032	radical SAM domain protein
RGRSB_0833	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
RGRSB_0834	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RGRSB_0837	COG1316	TRANSCRIPTIONal
RGRSB_0842	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RGRSB_0845	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
RGRSB_0846	COG0017	Asparaginyl-tRNA synthetase
RGRSB_0857	COG0537	adenosine 5'-monophosphoramidase activity
RGRSB_0858	COG0316	Belongs to the HesB IscA family
RGRSB_0860	COG0501	Belongs to the peptidase M48B family
RGRSB_0864	COG0463	Glycosyl transferase, family 2
RGRSB_0872	COG0438	transferase activity, transferring glycosyl groups
RGRSB_0875	COG0673	inositol 2-dehydrogenase activity
RGRSB_0888	COG0577	efflux transmembrane transporter activity
RGRSB_0888	COG1136	(ABC) transporter
RGRSB_0894	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RGRSB_0900	COG0077	Prephenate dehydratase
RGRSB_0900	COG1605	Chorismate mutase
RGRSB_0901	COG1530	ribonuclease E activity
RGRSB_0905	COG1104	cysteine desulfurase activity
RGRSB_0907	COG0793	Belongs to the peptidase S41A family
RGRSB_0912	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RGRSB_0916	COG0450	alkyl hydroperoxide reductase
RGRSB_0919	COG0484	heat shock protein binding
RGRSB_0923	COG0505	Belongs to the CarA family
RGRSB_0927	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
RGRSB_0930	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RGRSB_0931	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RGRSB_0932	COG0613	PHP domain protein
RGRSB_0936	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RGRSB_0938	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RGRSB_0940	COG0439	Biotin carboxylase
RGRSB_0946	COG0067	glutamate synthase
RGRSB_0946	COG0069	glutamate synthase activity
RGRSB_0946	COG0070	glutamate synthase
RGRSB_0948	COG0739	heme binding
RGRSB_0949	COG0460	homoserine dehydrogenase
RGRSB_0956	COG3854	ATPases associated with a variety of cellular activities
RGRSB_0962	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RGRSB_0964	COG0484	heat shock protein binding
RGRSB_0965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RGRSB_0967	COG1268	BioY protein
RGRSB_0972	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
RGRSB_0973	COG1702	phosphate starvation-inducible protein PhoH
RGRSB_0974	COG0649	NAD binding
RGRSB_0976	COG0037	tRNA processing
RGRSB_0987	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RGRSB_0989	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RGRSB_0990	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RGRSB_0991	COG0602	queuosine metabolic process
RGRSB_0993	COG0113	porphobilinogen synthase activity
RGRSB_0994	COG1187	pseudouridine synthase activity
RGRSB_0998	COG0579	oxidoreductase
RGRSB_0999	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RGRSB_0999	COG1754	DNA topoisomerase type I activity
RGRSB_1002	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RGRSB_1004	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RGRSB_1008	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
RGRSB_1016	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RGRSB_1018	COG0673	inositol 2-dehydrogenase activity
RGRSB_1019	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RGRSB_1019	COG0574	Belongs to the PEP-utilizing enzyme family
RGRSB_1021	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
RGRSB_1022	COG1950	PFAM Membrane protein of
RGRSB_1025	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RGRSB_1029	COG0470	DNA polymerase III
RGRSB_1031	COG2217	Heavy metal translocating P-type atpase
RGRSB_1033	COG0592	DNA-directed DNA polymerase activity
RGRSB_1038	COG0366	Alpha amylase catalytic
RGRSB_1040	COG1316	TRANSCRIPTIONal
RGRSB_1041	COG0515	serine threonine protein kinase
RGRSB_1044	COG0321	lipoyl(octanoyl) transferase activity
RGRSB_1045	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RGRSB_1049	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RGRSB_1051	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RGRSB_1054	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RGRSB_1058	COG1049	propionate catabolic process, 2-methylcitrate cycle
RGRSB_1069	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RGRSB_1073	COG0024	Methionine aminopeptidase
RGRSB_1075	COG1175	transmembrane transport
RGRSB_1076	COG0571	ribonuclease III activity
RGRSB_1079	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RGRSB_1082	COG0730	response to heat
RGRSB_1083	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RGRSB_1090	COG0802	atpase or kinase
RGRSB_1091	COG0391	Required for morphogenesis under gluconeogenic growth conditions
RGRSB_1094	COG0765	amino acid transport
RGRSB_1096	COG0837	glucose binding
RGRSB_1097	COG2131	deaminase
RGRSB_1100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RGRSB_1102	COG0542	response to heat
RGRSB_1103	COG1028	Short-chain dehydrogenase reductase Sdr
RGRSB_1104	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RGRSB_1105	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RGRSB_1106	COG0419	ATPase involved in DNA repair
RGRSB_1109	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RGRSB_1111	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RGRSB_1114	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RGRSB_1117	COG0316	Belongs to the HesB IscA family
RGRSB_1119	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RGRSB_1124	COG1045	serine acetyltransferase
RGRSB_1130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RGRSB_1131	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
RGRSB_1133	COG0285	dihydrofolate synthase activity
RGRSB_1134	COG0747	negative chemotaxis
RGRSB_1136	COG4372	Transposase
RGRSB_1137	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RGRSB_1138	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RGRSB_1140	COG2211	Major facilitator Superfamily
RGRSB_1146	COG1122	ATPase activity
RGRSB_1151	COG0390	transport system, permease component
RGRSB_1153	COG0140	phosphoribosyl-ATP diphosphatase activity
RGRSB_1153	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RGRSB_1154	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RGRSB_1161	COG0516	GMP reductase activity
RGRSB_1162	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RGRSB_1163	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RGRSB_1165	COG5002	protein histidine kinase activity
RGRSB_1167	COG0745	RESPONSE REGULATOR receiver
RGRSB_1169	COG0539	negative regulation of cytoplasmic translation
RGRSB_1171	COG2197	response regulator
RGRSB_1174	COG0434	BtpA family
RGRSB_1175	COG4243	Vitamin k epoxide reductase
RGRSB_1184	COG0511	ligase activity, forming carbon-carbon bonds
RGRSB_1187	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RGRSB_1190	COG0571	ribonuclease III activity
RGRSB_1191	COG0463	Glycosyl transferase, family 2
RGRSB_1196	COG0191	fructose-bisphosphate aldolase activity
RGRSB_1200	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RGRSB_1201	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RGRSB_1202	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RGRSB_1202	COG0512	Glutamine amidotransferase of anthranilate synthase
RGRSB_1206	COG0583	DNA-binding transcription factor activity
RGRSB_1217	COG0363	glucosamine-6-phosphate deaminase activity
RGRSB_1221	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RGRSB_1226	COG3409	Peptidoglycan-binding domain 1 protein
RGRSB_1226	COG3429	Glucose-6-phosphate dehydrogenase subunit
RGRSB_1227	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
RGRSB_1229	COG0432	Pfam Uncharacterised protein family UPF0047
RGRSB_1230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RGRSB_1235	COG1797	cobyrinic acid a,c-diamide synthase activity
RGRSB_1236	COG3659	wide pore channel activity
RGRSB_1238	COG0469	pyruvate kinase activity
RGRSB_1239	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RGRSB_1242	COG0312	modulator of DNA gyrase
RGRSB_1243	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
RGRSB_1244	COG0298	carbon dioxide binding
RGRSB_1246	COG1612	heme a metabolic process
RGRSB_1248	COG0488	(ABC) transporter
RGRSB_1250	COG0187	DNA topoisomerase II activity
RGRSB_1250	COG1372	Participates in initiation and elongation during chromosome replication
RGRSB_1251	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
RGRSB_1252	COG1193	negative regulation of DNA recombination
RGRSB_1254	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RGRSB_1255	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RGRSB_1256	COG0022	dehydrogenase e1 component
RGRSB_1256	COG0508	dehydrogenase complex catalyzes the overall conversion of
RGRSB_1263	COG0719	Fe-S assembly protein
RGRSB_1264	COG0396	ATPase activity
RGRSB_1265	COG0719	Fe-S assembly protein
RGRSB_1266	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RGRSB_1268	COG2715	membrane protein required for spore maturation
RGRSB_1270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RGRSB_1271	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RGRSB_1273	COG0538	isocitrate dehydrogenase activity
RGRSB_1279	COG2211	Major facilitator Superfamily
RGRSB_1282	COG0850	regulation of cytokinetic process
RGRSB_1283	COG2894	cell division
RGRSB_1284	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
RGRSB_1285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RGRSB_1289	COG1640	4-alpha-glucanotransferase
RGRSB_1290	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RGRSB_1292	COG0302	gtp cyclohydrolase
RGRSB_1293	COG4221	oxidoreductase activity
RGRSB_1297	COG0612	Peptidase, M16
RGRSB_1303	COG0250	Participates in transcription elongation, termination and antitermination
RGRSB_1304	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RGRSB_1307	COG0659	secondary active sulfate transmembrane transporter activity
RGRSB_1308	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RGRSB_1312	COG0612	Peptidase, M16
RGRSB_1313	COG0740	serine-type endopeptidase activity
RGRSB_1315	COG0557	exoribonuclease II activity
RGRSB_1327	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
RGRSB_1328	COG5002	protein histidine kinase activity
RGRSB_1329	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RGRSB_1330	COG0497	DNA recombination
RGRSB_1331	COG0095	Lipoate-protein ligase
RGRSB_1333	COG0735	belongs to the Fur family
RGRSB_1338	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RGRSB_1339	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RGRSB_1341	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RGRSB_1348	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RGRSB_1350	COG0174	glutamine synthetase
RGRSB_1355	COG1940	carbohydrate kinase activity
RGRSB_1357	COG0617	tRNA 3'-terminal CCA addition
RGRSB_1359	COG0515	serine threonine protein kinase
RGRSB_1360	COG1032	radical SAM domain protein
RGRSB_1365	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RGRSB_1365	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RGRSB_1366	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RGRSB_1367	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RGRSB_1371	COG0513	Belongs to the DEAD box helicase family
RGRSB_1373	COG2197	response regulator
RGRSB_1376	COG0196	riboflavin kinase activity
RGRSB_1380	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RGRSB_1385	COG0571	ribonuclease III activity
RGRSB_1386	COG2188	Transcriptional regulator
RGRSB_1389	COG4451	ribulose bisphosphate carboxylase, small
RGRSB_1394	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
RGRSB_1395	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
RGRSB_1396	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RGRSB_1397	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RGRSB_1399	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
RGRSB_1402	COG0768	penicillin binding
RGRSB_1403	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RGRSB_1404	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RGRSB_1405	COG1845	cytochrome c oxidase, subunit III
RGRSB_1406	COG0003	Pfam Anion-transporting ATPase
RGRSB_1409	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
RGRSB_1410	COG1090	epimerase
RGRSB_1413	COG0459	protein refolding
RGRSB_1420	COG3273	potassium ion transport
RGRSB_1420	COG0471	metal ion transport
RGRSB_1426	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RGRSB_1430	COG1691	(AIR) carboxylase
RGRSB_1433	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RGRSB_1435	COG3264	Mechanosensitive ion channel
RGRSB_1435	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
RGRSB_1441	COG0678	peroxiredoxin activity
RGRSB_1443	COG1132	(ABC) transporter
RGRSB_1445	COG2217	Heavy metal translocating P-type atpase
RGRSB_1451	COG1131	(ABC) transporter
RGRSB_1455	COG0861	Integral membrane protein TerC family
RGRSB_1456	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RGRSB_1461	COG0572	uridine kinase
RGRSB_1463	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RGRSB_1466	COG1192	Involved in chromosome partitioning
RGRSB_1469	COG1543	Belongs to the glycosyl hydrolase 57 family
RGRSB_1471	COG0463	Glycosyl transferase, family 2
RGRSB_1471	COG0457	Tetratricopeptide repeat
RGRSB_1474	COG0346	lactoylglutathione lyase activity
RGRSB_1475	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RGRSB_1477	COG0514	ATP-dependent DNA helicase (RecQ)
RGRSB_1478	COG0463	Glycosyl transferase, family 2
RGRSB_1479	COG0542	response to heat
RGRSB_1481	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RGRSB_1481	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RGRSB_1483	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RGRSB_1487	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RGRSB_1488	COG1166	arginine decarboxylase activity
RGRSB_1489	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RGRSB_1495	COG0310	cobalt ion transport
RGRSB_1496	COG0358	DNA primase activity
RGRSB_1498	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
RGRSB_1502	COG3118	belongs to the thioredoxin family
RGRSB_1504	COG0824	Thioesterase
RGRSB_1508	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RGRSB_1509	COG0363	glucosamine-6-phosphate deaminase activity
RGRSB_1514	COG0590	tRNA wobble adenosine to inosine editing
RGRSB_1516	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RGRSB_1517	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
RGRSB_1518	COG0019	diaminopimelate decarboxylase activity
RGRSB_1519	COG0720	synthase
RGRSB_1520	COG4783	chaperone-mediated protein folding
RGRSB_1522	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RGRSB_1522	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RGRSB_1524	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RGRSB_1526	COG0583	DNA-binding transcription factor activity
RGRSB_1528	COG0463	Glycosyl transferase, family 2
RGRSB_1534	COG5554	nitrogen fixation
RGRSB_1535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RGRSB_1538	COG1045	serine acetyltransferase
RGRSB_1542	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RGRSB_1542	COG2906	2 iron, 2 sulfur cluster binding
RGRSB_1542	COG0822	iron-sulfur transferase activity
RGRSB_1550	COG5420	small protein containing a coiled-coil domain
RGRSB_1558	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
RGRSB_1561	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RGRSB_1562	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
RGRSB_1572	COG0501	Belongs to the peptidase M48B family
RGRSB_1575	COG0745	RESPONSE REGULATOR receiver
RGRSB_1582	COG0628	permease
RGRSB_1583	COG1074	ATP-dependent DNA helicase activity
RGRSB_1592	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RGRSB_1597	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RGRSB_1597	COG2022	thiamine diphosphate biosynthetic process
RGRSB_1598	COG1836	PFAM Integral membrane protein DUF92
RGRSB_1599	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RGRSB_1603	COG0713	ATP synthesis coupled electron transport
RGRSB_1604	COG0839	Belongs to the complex I subunit 6 family
RGRSB_1605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RGRSB_1607	COG0561	phosphatase activity
RGRSB_1609	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RGRSB_1613	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RGRSB_1615	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RGRSB_1616	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
RGRSB_1619	COG0131	Imidazoleglycerol-phosphate dehydratase
RGRSB_1622	COG0723	plastoquinol--plastocyanin reductase activity
RGRSB_1626	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RGRSB_1626	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RGRSB_1632	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RGRSB_1632	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RGRSB_1636	COG0701	Predicted permease
RGRSB_1641	COG1597	lipid kinase activity
RGRSB_1642	COG1606	tRNA processing
RGRSB_1643	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RGRSB_1647	COG0189	ligase activity
RGRSB_1649	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RGRSB_1649	COG0072	phenylalanine-tRNA ligase activity
RGRSB_1650	COG1088	dTDP-glucose 4,6-dehydratase activity
RGRSB_1654	COG0003	Pfam Anion-transporting ATPase
RGRSB_1655	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RGRSB_1660	COG4251	negative regulation of phosphorylation
RGRSB_1661	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
RGRSB_1663	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RGRSB_1666	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RGRSB_1670	COG0539	negative regulation of cytoplasmic translation
RGRSB_1673	COG0741	lytic transglycosylase activity
RGRSB_1678	COG0750	zinc metalloprotease
RGRSB_1679	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RGRSB_1683	COG0706	membrane insertase activity
RGRSB_1686	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
RGRSB_1687	COG0784	Response regulator, receiver
RGRSB_1687	COG2205	protein histidine kinase activity
RGRSB_1691	COG0271	Belongs to the BolA IbaG family
RGRSB_1692	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RGRSB_1694	COG0745	RESPONSE REGULATOR receiver
RGRSB_1696	COG0170	dolichyl monophosphate biosynthetic process
RGRSB_1697	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RGRSB_1698	COG0740	serine-type endopeptidase activity
RGRSB_1705	COG0012	GTP binding
RGRSB_1706	COG0384	phenazine biosynthesis protein PhzF
RGRSB_1710	COG3536	Protein conserved in bacteria
RGRSB_1712	COG0484	heat shock protein binding
RGRSB_1713	COG0443	Heat shock 70 kDa protein
RGRSB_1716	COG0776	regulation of translation
RGRSB_1717	COG1480	7TM receptor with intracellular HD hydrolase
RGRSB_1721	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RGRSB_1726	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RGRSB_1727	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
RGRSB_1728	COG0800	Aldolase
RGRSB_1733	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RGRSB_1738	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RGRSB_1739	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RGRSB_1741	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RGRSB_1742	COG0483	inositol monophosphate 1-phosphatase activity
RGRSB_1745	COG0107	imidazoleglycerol-phosphate synthase activity
RGRSB_1749	COG0745	RESPONSE REGULATOR receiver
RGRSB_1752	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RGRSB_1753	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RGRSB_1759	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RGRSB_1761	COG0438	transferase activity, transferring glycosyl groups
RGRSB_1762	COG0629	single-stranded DNA binding
RGRSB_1763	COG1077	Cell shape determining protein MreB Mrl
RGRSB_1766	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RGRSB_1768	COG0387	Pfam Sodium calcium exchanger
RGRSB_1773	COG0668	transmembrane transport
RGRSB_1777	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RGRSB_1780	COG1116	anion transmembrane transporter activity
RGRSB_1780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RGRSB_1782	COG0815	Transfers the fatty acyl group on membrane lipoproteins
RGRSB_1783	COG0803	Belongs to the bacterial solute-binding protein 9 family
RGRSB_1784	COG1121	(ABC) transporter
RGRSB_1785	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RGRSB_1787	COG0523	cobalamin synthesis protein
RGRSB_1788	COG1982	Orn Lys Arg decarboxylase major
RGRSB_1789	COG0616	signal peptide processing
RGRSB_1792	COG0772	Belongs to the SEDS family
RGRSB_1793	COG0489	protein tyrosine kinase activity
RGRSB_1798	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RGRSB_1801	COG0114	fumarate hydratase activity
RGRSB_1807	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RGRSB_1811	COG0151	Belongs to the GarS family
RGRSB_1812	COG3339	Conserved Protein
RGRSB_1814	COG1845	cytochrome c oxidase, subunit III
RGRSB_1816	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RGRSB_1819	COG1252	NADH dehydrogenase
RGRSB_1824	COG0415	Belongs to the DNA photolyase family
RGRSB_1825	COG0494	nUDIX hydrolase
RGRSB_1826	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
RGRSB_1827	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RGRSB_1828	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
RGRSB_1828	COG0662	Cupin 2, conserved barrel domain protein
RGRSB_1831	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RGRSB_1832	COG0398	Pfam SNARE associated Golgi protein
RGRSB_1834	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RGRSB_1836	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RGRSB_1837	COG1657	PFAM Prenyltransferase squalene oxidase
RGRSB_1839	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RGRSB_1839	COG2022	thiamine diphosphate biosynthetic process
RGRSB_1841	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
RGRSB_1843	COG0322	excinuclease ABC activity
RGRSB_1844	COG0395	ABC-type sugar transport system, permease component
RGRSB_1848	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RGRSB_1861	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RGRSB_1862	COG0189	ligase activity
RGRSB_1874	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RGRSB_1877	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RGRSB_1878	COG1372	Participates in initiation and elongation during chromosome replication
RGRSB_1878	COG0305	Participates in initiation and elongation during chromosome replication
RGRSB_1882	COG1136	(ABC) transporter
RGRSB_1882	COG0577	efflux transmembrane transporter activity
RGRSB_1884	COG0459	protein refolding
RGRSB_1886	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RGRSB_1887	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RGRSB_1891	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RGRSB_1899	COG1132	(ABC) transporter
RGRSB_1902	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RGRSB_1905	COG0772	Belongs to the SEDS family
RGRSB_1915	COG0730	response to heat
RGRSB_1921	COG0157	Belongs to the NadC ModD family
RGRSB_1924	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RGRSB_1927	COG2081	HI0933 family
RGRSB_1928	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RGRSB_1932	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RGRSB_1933	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
RGRSB_1934	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RGRSB_1935	COG0739	heme binding
RGRSB_1938	COG2197	response regulator
RGRSB_1939	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
RGRSB_1943	COG3118	belongs to the thioredoxin family
RGRSB_1944	COG1842	Phage shock protein A
RGRSB_1945	COG1842	Phage shock protein A
RGRSB_1949	COG1253	flavin adenine dinucleotide binding
RGRSB_1950	COG0058	SHG alpha-glucan phosphorylase activity
RGRSB_1951	COG1420	regulation of RNA biosynthetic process