locus-tag	class	description
I862_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
I862_00015	ENOG4105CE9	30S ribosomal protein S2
I862_00020	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
I862_00025	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
I862_00030	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
I862_00040	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
I862_00050	ENOG4105CN1	protease
I862_00055	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I862_00065	ENOG4105BZE	flagellar hook protein, FlgE
I862_00070	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
I862_00075	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
I862_00090	ENOG4105C7J	ABC transporter, permease
I862_00130	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
I862_00135	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
I862_00150	ENOG4105BZU	Histidine kinase
I862_00160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
I862_00170	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
I862_00175	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
I862_00180	ENOG4105MJ2	Competence protein
I862_00190	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
I862_00205	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
I862_00215	ENOG4108VX5	3-methyladenine DNA glycosylase
I862_00230	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
I862_00235	ENOG4107G9V	glycosyl transferase, family 39
I862_00245	ENOG4105CW7	secretion protein, HlyD family
I862_00250	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
I862_00255	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
I862_00260	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
I862_00275	ENOG4105HHA	aminodeoxychorismate lyase
I862_00280	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
I862_00285	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
I862_00290	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
I862_00315	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
I862_00330	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
I862_00345	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
I862_00380	ENOG4105PGM	cation diffusion facilitator family transporter
I862_00385	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I862_00400	ENOG4105CI3	gtp-binding protein typa
I862_00410	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
I862_00425	ENOG4105U0R	haloacid dehalogenase-like hydrolase
I862_00440	ENOG4105ESV	Glycosyl transferase, family 4
I862_00455	ENOG4105C58	cytochrome c oxidase accessory protein ccog
I862_00495	ENOG4108URH	decarboxylase
I862_00500	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
I862_00510	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
I862_00515	ENOG4108R6K	riboflavin synthase, subunit alpha
I862_00520	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
I862_00540	ENOG4108K3A	Glutathione S-transferase
I862_00545	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
I862_00560	ENOG4105RHY	Pfam:UPF0157
I862_00570	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
I862_00575	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
I862_00580	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
I862_00585	ENOG4105C59	p-type ATPase
I862_00610	ENOG4105W5Q	DNA repair protein (RadC
I862_00615	ENOG4107QX3	carboxylase
I862_00640	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
I862_00650	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
I862_00660	ENOG4105K3G	Periplasmic Protein
I862_00665	ENOG4105K3G	Periplasmic Protein
I862_00680	ENOG4108S0S	Nucleotidyl transferase
I862_00685	ENOG4105EHM	Aminoglycoside phosphotransferase
I862_00695	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
I862_00705	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
I862_00715	ENOG4108RG0	uracil-dna glycosylase
I862_00725	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
I862_00730	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
I862_00735	ENOG4105KNE	Phosphatidate cytidylyltransferase
I862_00740	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
I862_00755	ENOG4107QN2	dihydrolipoyl dehydrogenase
I862_00765	ENOG4105C7S	Dehydrogenase
I862_00775	ENOG4105D5Q	Arginine ornithine antiporter
I862_00780	ENOG4105VN1	Heat shock protein
I862_00805	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
I862_00810	ENOG4105E18	UPF0276 protein
I862_00820	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
I862_00860	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
I862_00870	ENOG4105WG9	Conserved Protein
I862_00895	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
I862_00915	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
I862_00920	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
I862_00925	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
I862_00940	ENOG4105HS1	biotin--protein ligase
I862_00945	ENOG4105BZU	Histidine kinase
I862_00950	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
I862_00955	ENOG41072GX	Peptidase M22 Glycoprotease
I862_00960	ENOG41082WC	Transport-associated protein
I862_00965	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
I862_00970	ENOG4105C7Z	Conserved Protein
I862_00980	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
I862_01025	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
I862_01030	ENOG4105D00	flagellar biosynthetic protein flhB
I862_01035	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
I862_01040	ENOG410862U	Carbon storage regulator
I862_01050	ENOG4108I0Z	Aconitate hydratase
I862_01075	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
I862_01095	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
I862_01100	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
I862_01105	ENOG4105CNI	cell division protein FtsW
I862_01110	ENOG4105CNI	cell division protein FtsW
I862_01150	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
I862_01175	ENOG4105C26	Dehydrogenase
I862_01180	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
I862_01185	ENOG41069HH	4-oxalocrotonate tautomerase
I862_01205	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
I862_01210	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
I862_01215	ENOG4105C3F	Signal peptidase i
I862_01235	ENOG4108Z6B	deaminase
I862_01240	ENOG4105EYM	Major Facilitator superfamily
I862_01245	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
I862_01260	ENOG4105C5H	ABC transporter
I862_01270	ENOG4105FE9	pseudouridine synthase
I862_01275	ENOG4108Z86	Glutamine amidotransferase
I862_01280	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
I862_01285	ENOG41090R7	Ferric uptake
I862_01295	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
I862_01310	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
I862_01320	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
I862_01335	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
I862_01395	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
I862_01405	ENOG41090SZ	ABC-2 type transporter
I862_01425	ENOG41084CK	capsule polysaccharide
I862_01440	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
I862_01445	ENOG4105C98	muts2 protein
I862_01455	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
I862_01465	ENOG4105E02	MotA TolQ exbB proton channel
I862_01470	ENOG4105M8F	Biopolymer transport protein exbD tolR
I862_01495	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
I862_01500	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
I862_01505	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
I862_01525	ENOG4106909	Flagellar assembly regulator FliX
I862_01530	ENOG4108IEH	NADH dehydrogenase subunit g
I862_01535	ENOG4105CS1	NAD(P)H quinone oxidoreductase
I862_01540	ENOG4105C2C	drug resistance transporter, Bcr CflA
I862_01545	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
I862_01560	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
I862_01565	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
I862_01575	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
I862_01595	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
I862_01615	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
I862_01620	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
I862_01655	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
I862_01660	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
I862_01675	ENOG4108JJ6	Type I secretion system ATPase
I862_01680	ENOG4105T40	surface antigen msp4 family protein
I862_01705	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
I862_01730	ENOG4108AWY	Nucleoside-diphosphate-sugar epimerase
I862_01735	ENOG4105KDC	50s ribosomal protein l28
I862_01740	ENOG4106S8I	
I862_01760	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
I862_01775	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
I862_01780	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
I862_01785	ENOG4105D7Q	type ii secretion system
I862_01790	ENOG4107QHF	type ii secretion system protein e
I862_01800	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
I862_01805	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
I862_01810	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
I862_01815	ENOG41069AG	Ankyrin repeat
I862_01820	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
I862_01830	ENOG4105CUT	histidyl-tRNA synthetase
I862_01835	ENOG4107QJE	Chromosome Partitioning Protein
I862_01840	ENOG4105KT5	UmuD protein
I862_01850	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
I862_01870	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
I862_01875	ENOG4108UFP	Essential cell division protein (By similarity)
I862_01880	ENOG4105CPF	Cell wall formation (By similarity)
I862_01895	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
I862_01900	ENOG4108Z03	MAF-like protein
I862_01910	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
I862_01920	ENOG4106H78	methyltransferase
I862_01930	ENOG4105CMM	transposase
I862_01985	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
I862_01990	ENOG4105CMM	transposase
I862_02040	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
I862_02130	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
I862_02135	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
I862_02195	ENOG4105BZU	Histidine kinase
I862_02200	ENOG4105C2N	RNA methyltransferase TrmH family group 3
I862_02210	ENOG4105C2X	Arabinose 5-phosphate isomerase
I862_02235	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
I862_02245	ENOG4108Z1Z	gCN5-related N-acetyltransferase
I862_02255	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
I862_02260	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
I862_02270	ENOG4105VIE	preprotein translocase, subunit YajC
I862_02275	ENOG4105DHI	Methyltransferase
I862_02280	ENOG41083MR	nifu domain-containing protein
I862_02285	ENOG4105ER2	Ompa motb domain protein
I862_02290	ENOG4107RD7	Flagellar Motor Protein, MotA
I862_02295	ENOG4107QPK	)-transporter
I862_02345	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
I862_02350	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
I862_02360	ENOG4107XM9	(LipO)protein
I862_02365	ENOG4105CAY	ferredoxin--nadp reductase
I862_02370	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
I862_02375	ENOG4107U9T	Pfam:Ribonuclease_BN
I862_02385	ENOG4108ZUW	Major pilin subunit
I862_02390	ENOG4105CGK	Exodeoxyribonuclease III
I862_02395	ENOG4105DNE	Transposase
I862_02440	ENOG4105CHR	reductase
I862_02445	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
I862_02460	ENOG4105CJR	Integral membrane protein (MviN
I862_02465	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
I862_02470	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
I862_02480	ENOG4105K5M	30s ribosomal protein S16
I862_02500	ENOG4105D1F	ATP-binding protein
I862_02505	ENOG4107RIZ	hflk protein
I862_02515	ENOG4105WVQ	Fe-S assembly protein IscX
I862_02550	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
I862_02555	ENOG4105BZ1	(ABC) transporter
I862_02560	ENOG4105C03	ribonuclease
I862_02570	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
I862_02575	ENOG4105C3G	gtp-binding protein
I862_02595	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
I862_02625	ENOG4105BZU	Histidine kinase
I862_02630	ENOG4108UXN	response regulator
I862_02640	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I862_02645	ENOG4105DJV	ribulose-phosphate 3-epimerase
I862_02650	ENOG4105CBT	Fructose-1,6-bisphosphatase
I862_02675	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
I862_02700	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
I862_02705	ENOG4105VFN	O-Antigen polymerase
I862_02845	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
I862_02850	ENOG4105C1V	Peptidase, M16
I862_02865	ENOG4105C6K	Malic enzyme
I862_02870	ENOG4108Z4U	Ferredoxin
I862_02875	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
I862_02880	ENOG4107ZHD	antitermination protein nusB
I862_02890	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
I862_02900	ENOG4105K70	DNA-binding protein
I862_02905	ENOG4108Z0R	Transferase
I862_02910	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
I862_02925	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
I862_02935	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
I862_02940	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
I862_02945	ENOG4105C8S	subunit m
I862_02950	ENOG4105D65	subunit l
I862_02955	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
I862_02960	ENOG4105DF2	NADH dehydrogenase subunit j
I862_02985	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
I862_03035	ENOG4105KAV	tspo and mbr like protein
I862_03070	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
I862_03080	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
I862_03130	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
I862_03140	ENOG4106HFR	
I862_03155	ENOG4107QSV	RmuC domain protein
I862_03180	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
I862_03195	ENOG41067F4	Cytidylyltransferase family
I862_03205	ENOG4105DD5	Flagellar motor switch protein
I862_03215	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
I862_03220	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
I862_03245	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
I862_03250	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
I862_03265	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
I862_03275	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
I862_03295	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
I862_03300	ENOG4105CUB	amino acid
I862_03315	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
I862_03320	ENOG4105CA3	membrane-bound lytic murein transglycosylase
I862_03330	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
I862_03335	ENOG4105VS8	Flagellar biosynthetic protein fliq
I862_03340	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
I862_03350	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
I862_03360	ENOG4106ABQ	septum formation initiator
I862_03365	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
I862_03375	ENOG4105DC7	peptidase M24
I862_03380	ENOG4105DC7	peptidase M24
I862_03410	ENOG4105BZ1	(ABC) transporter
I862_03415	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
I862_03425	ENOG4105D6Z	AFG1 family ATPase
I862_03430	ENOG4105DU1	integral membrane protein, terc
I862_03435	ENOG4105EIE	fructose-bisphosphate aldolase
I862_03440	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
I862_03445	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
I862_03465	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
I862_03490	ENOG4105RPH	Inner membrane protein YddG
I862_03500	ENOG4105BZU	Histidine kinase
I862_03505	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
I862_03515	ENOG4105E7T	carrier protein
I862_03525	ENOG4105C0P	Mg chelatase subunit ChlI
I862_03530	ENOG4105BZU	Histidine kinase
I862_03550	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
I862_03555	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
I862_03560	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
I862_03565	ENOG4108VZM	50s ribosomal protein L10
I862_03570	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
I862_03575	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
I862_03580	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
I862_03595	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
I862_03600	ENOG4108IUZ	ABC transporter
I862_03615	ENOG41063C6	UPF0235 protein
I862_03620	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
I862_03655	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
I862_03685	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
I862_03700	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
I862_03710	ENOG4105DFU	Cell wall formation (By similarity)
I862_03715	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I862_03730	ENOG4105W0E	50S ribosomal protein L33
I862_03735	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
I862_03740	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
I862_03750	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
I862_03770	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
I862_03780	ENOG4105CHR	reductase
I862_03790	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
I862_03815	ENOG4105D7Z	glutathione synthase
I862_03820	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
I862_03830	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
I862_03840	ENOG41082BR	50S ribosomal protein L35
I862_03850	ENOG4107QJT	sodium dicarboxylate symporter
I862_03875	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
I862_03880	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
I862_03890	ENOG4105C8T	Leucyl-tRNA synthetase
I862_03900	ENOG4105D52	delta-aminolevulinic acid dehydratase
I862_03920	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
I862_03925	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
I862_03935	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
I862_03940	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
I862_03945	ENOG4107YZM	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
I862_03950	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
I862_03955	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
I862_03960	ENOG4105CTB	Polyprenyl synthetase
I862_03965	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
I862_03970	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
I862_03975	ENOG4105VFF	UPF0102 protein
I862_03980	ENOG4105CZX	twitching motility protein
I862_03990	ENOG4105CK7	Sodium proline symporter
I862_03995	ENOG4105K59	histidine triad (HIT) protein
I862_04000	ENOG4105D1S	lipid A biosynthesis
I862_04010	ENOG4105DZ1	carboxypeptidase
I862_04030	ENOG4105CNH	Multidrug resistance protein MdtL
I862_04045	ENOG4105BZU	Histidine kinase
I862_04050	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
I862_04055	ENOG4107QMP	dna polymerase iii subunits gamma and tau
I862_04060	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
I862_04070	ENOG4105CTD	carboxy-peptidase
I862_04075	ENOG4105E0F	Histidine kinase
I862_04080	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
I862_04085	ENOG4107QP8	phosphohexose isomerase
I862_04090	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
I862_04115	ENOG4106TJ0	
I862_04135	ENOG4105BZU	Histidine kinase
I862_04140	ENOG4105ETX	regulatoR
I862_04150	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
I862_04155	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
I862_04205	ENOG4105BZU	Histidine kinase
I862_04345	ENOG4108ES9	ParB domain protein nuclease
I862_04440	ENOG4105BZU	Histidine kinase
I862_04445	ENOG4105YK5	50S ribosomal protein L36
I862_04465	ENOG4105CN7	Flagellar biosynthetic protein FliP
I862_04485	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
I862_04490	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
I862_04495	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
I862_04505	ENOG41082FS	50S ribosomal protein L31
I862_04520	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
I862_04525	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
I862_04530	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
I862_04540	ENOG4105CJN	penicillin-binding protein
I862_04550	ENOG4105EUJ	GTP cyclohydrolase i
I862_04580	ENOG4105DFI	Membrane
I862_04605	ENOG4107F58	2'-5' rna ligase
I862_04610	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
I862_04615	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
I862_04635	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
I862_04645	ENOG4108WIW	Aspartyl protease
I862_04650	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
I862_04670	ENOG4107RCQ	(CBS) domain
I862_04675	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
I862_04680	ENOG4105C9A	Phoh family
I862_04685	ENOG4105T40	surface antigen msp4 family protein
I862_04700	ENOG4105DZ1	carboxypeptidase
I862_04705	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
I862_04745	ENOG4108V42	Type IV secretion system protein VirB8
I862_04755	ENOG4105CMA	conjugation trbi family protein
I862_04775	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
I862_04780	ENOG4105C4M	(Ubiquinol oxidase) subunit I
I862_04810	ENOG4107VXZ	Hydrolase
I862_04815	ENOG4105BZ1	(ABC) transporter
I862_04820	ENOG4105F0N	pyrophosphate phospho-hydrolase
I862_04825	ENOG4105C72	UPF0176 protein
I862_04840	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
I862_04850	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
I862_04860	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
I862_04865	ENOG4105KTQ	flagellar basal-body rod protein
I862_04870	ENOG4105CGA	flagellar basal-body rod protein FlgG
I862_04880	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
I862_04900	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I862_04905	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
I862_04915	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
I862_04920	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
I862_04930	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
I862_04935	ENOG4105K46	50S ribosomal protein l27
I862_04945	ENOG4105X50	flagellar hook-basal body complex protein fliE
I862_04950	ENOG4108ZC9	flagellar basal-body rod protein flgc
I862_04955	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
I862_04960	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
I862_04980	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
I862_04990	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
I862_04995	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
I862_05000	ENOG41082R8	50S ribosomal protein l32
I862_05040	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
I862_05050	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
I862_05055	ENOG41068WN	
I862_05065	ENOG4108UJD	30S ribosomal protein S9
I862_05070	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
I862_05075	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
I862_05080	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
I862_05085	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
I862_05115	ENOG4107QN2	dihydrolipoyl dehydrogenase
I862_05140	ENOG4105C7I	Dehydrogenase
I862_05155	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
I862_05160	ENOG4105C0B	DNA polymerase III (alpha subunit)
I862_05195	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
I862_05210	ENOG4106HA5	Protein of unknown function (DUF2497) 
I862_05225	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
I862_05230	ENOG4108STX	response regulator
I862_05260	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
I862_05270	ENOG4105CEV	competence damage-inducible protein
I862_05280	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
I862_05295	ENOG4105W00	Flagellar hook capping protein
I862_05320	ENOG4105BZU	Histidine kinase
I862_05335	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
I862_05345	ENOG4105C9M	aspartyl-trna synthetase
I862_05355	ENOG4105CSA	Coproporphyrinogen iii oxidase
I862_05360	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
I862_05375	ENOG4105D3R	alkyl hydroperoxide reductase
I862_05380	ENOG4105C3M	thioredoxin reductase
I862_05385	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
I862_05390	ENOG4108UJU	UPF0301 protein
I862_05425	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
I862_05435	ENOG41060IM	Heme exporter protein
I862_05445	ENOG4107R8N	Glycosyl transferase, family 2
I862_05450	ENOG4108Z1B	Cyclase dehydrase
I862_05455	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
I862_05465	ENOG4105BZA	Phosphoglycerate kinase
I862_05470	ENOG41085PJ	rdd domain containing protein
I862_05490	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
I862_05495	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
I862_05505	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
I862_05520	ENOG4107QP7	CoA-transferase subunit A
I862_05525	ENOG4105CSH	Transporter
I862_05540	ENOG4105BZS	acriflavin resistance protein
I862_05560	ENOG4105BZ1	(ABC) transporter
I862_05585	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
I862_05590	ENOG4105CFH	Aspartokinase
I862_05595	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
I862_05600	ENOG4105MQ2	17 kDa surface antigen
I862_05610	ENOG4105CSM	endonuclease III
I862_05620	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
I862_05625	ENOG4108JDX	DNA polymerase iii, epsilon subunit
I862_05640	ENOG4105D17	glycoside hydrolase, family 3 domain protein
I862_05650	ENOG4105CKK	Glycosyl transferase, family 2
I862_05655	ENOG4105CSH	Transporter
I862_05660	ENOG4105DK7	lysyl-tRNA synthetase
I862_05675	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
I862_05690	ENOG4105C75	arginyL-tRNA synthetase
I862_05695	ENOG4105DJB	Major Facilitator Superfamily
I862_05710	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
I862_05715	ENOG4105KCK	Peptidoglycan-associated lipoprotein
I862_05720	ENOG4105F6E	Acyl-transferase
I862_05745	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
I862_05755	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
I862_05770	ENOG4108ZT0	50S ribosomal protein l17
I862_05775	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
I862_05780	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
I862_05785	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
I862_05790	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
I862_05795	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
I862_05800	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
I862_05805	ENOG4105VPB	50S ribosomal protein L30
I862_05810	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
I862_05815	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
I862_05820	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
I862_05825	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
I862_05830	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
I862_05835	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
I862_05845	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
I862_05855	ENOG41083MP	50s ribosomal protein l29
I862_05860	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
I862_05865	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
I862_05870	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
I862_05875	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
I862_05880	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
I862_05885	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
I862_05890	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
I862_05895	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
I862_05900	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
I862_05905	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
I862_05910	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
I862_05915	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
I862_05920	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
I862_05930	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
I862_05935	ENOG4105VUH	addiction module killer protein
I862_05940	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
I862_05945	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
I862_05960	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
I862_05965	ENOG4108E87	P-loop hydrolase UPF0079
I862_05970	ENOG4108JQC	penicillin-binding protein 1A
I862_05975	ENOG4107QIZ	NADH dehydrogenase
I862_05980	ENOG4107RD7	Flagellar Motor Protein, MotA
I862_05985	ENOG4107QUT	magnesium and cobalt transport protein CorA
I862_05990	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
I862_05995	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
I862_06000	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
I862_06005	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
I862_06010	ENOG4105F8V	Hydrolase, tatD family
I862_06015	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
I862_06020	ENOG4107PQ6	Inherit from NOG: atp synthase
I862_06030	ENOG41085Y2	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
I862_06040	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
I862_06050	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
I862_06055	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
I862_06060	ENOG4105HFZ	Membrane
I862_06065	ENOG4105G9V	cytochrome C
I862_06075	ENOG4107QX8	SPFH domain, Band 7 family protein
I862_06095	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
I862_06110	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
I862_06120	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
I862_06125	ENOG4107ZH2	Coenzyme PQQ synthesis protein C
I862_06135	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
I862_06145	ENOG4105C79	DNA protecting protein DprA
I862_06150	ENOG4107QMP	dna polymerase iii subunits gamma and tau
I862_06155	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
I862_06170	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
I862_06180	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
I862_06185	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
I862_06190	ENOG4105D4A	Cell wall formation (By similarity)
I862_06195	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
I862_06200	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
I862_06240	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
I862_06245	ENOG4105EAH	synthase
I862_06260	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
I862_06270	ENOG4105CHM	Aminotransferase
I862_06275	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
I862_06285	ENOG4108Z4V	iron-sulfur cluster assembly
I862_06290	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
I862_06295	ENOG4105C3J	Cysteine desulfurase
I862_06300	ENOG4107QI6	Cysteine desulfurase
I862_06305	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
I862_06310	ENOG4105DHZ	alpha beta
I862_06325	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
I862_06350	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
I862_06355	ENOG4105DZP	Membrane-associated zinc metalloprotease
I862_06360	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
I862_06365	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
I862_06385	ENOG4105DQ6	Transposase
I862_06410	ENOG4105W5Q	DNA repair protein (RadC
I862_06430	ENOG4108JIR	Flagellum-specific ATP synthase
I862_06455	ENOG4105E0M	Sulfatase
I862_06460	ENOG4105C4K	Nad synthetase
I862_06475	ENOG4108NG5	type IV secretion system protein
I862_06480	ENOG4108NG5	type IV secretion system protein
I862_06510	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
I862_06515	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
I862_06520	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
I862_06530	ENOG4105BZU	Histidine kinase
I862_06535	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
I862_06565	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
I862_06600	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
I862_06605	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
I862_06610	ENOG41067YR	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
I862_06615	ENOG4105VG0	50S ribosomal protein l34
I862_06620	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
I862_06625	ENOG4105DTN	riboflavin biosynthesis protein ribF
I862_06635	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
I862_06640	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
I862_06645	ENOG4108JYK	Dehydrogenase
I862_06660	ENOG4105BZ1	(ABC) transporter
I862_06670	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
I862_06725	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
I862_06735	ENOG4105CH7	arginosuccinase
I862_06745	ENOG4105C5H	ABC transporter
I862_06755	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
I862_06760	ENOG4105CDY	transcriptional regulatory protein
I862_06765	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
I862_06770	ENOG4105C02	permease
I862_06775	ENOG4105Y2X	UPF0335 protein
I862_06790	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
I862_06800	ENOG4105C5F	glutamine synthetase
I862_06810	ENOG4107SC1	transglycosylase
I862_06815	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
I862_06820	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
I862_06825	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
I862_06830	ENOG4107QJE	Chromosome Partitioning Protein
I862_06835	ENOG4105FA0	parb-like partition protein
I862_06850	ENOG4105KGF	protein, YerC YecD
I862_06880	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
I862_06885	ENOG4105CDU	Replicative dna helicase
I862_06890	ENOG4105BZU	Histidine kinase
I862_06905	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
I862_06910	ENOG4105BZU	Histidine kinase
I862_06915	ENOG4108YXA	Membrane
I862_06935	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
I862_06955	ENOG4105C9Q	fumarate hydratase class II
I862_06960	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
I862_06975	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
I862_06980	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
I862_06995	ENOG4108K5P	(LipO)protein
I862_06995	ENOG4108K5P	(LipO)protein
I862_07020	ENOG4105CP7	Triose-phosphate isomerase
I862_07045	ENOG4105D7B	Flagellar biosynthesis protein flha
I862_07055	ENOG4105C8N	cysteinyl-tRNA synthetase
I862_07070	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
I862_07075	ENOG4105CM2	brancheD-chain amino acid aminotransferase
I862_07080	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
I862_07085	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
I862_07090	ENOG4108HW3	(ABC) transporter
I862_07095	ENOG4105E5Q	amino acid AbC transporter
I862_07100	ENOG4105CDA	abc transporter atp-binding protein
I862_07120	ENOG4105I03	Flagellin
I862_07125	ENOG4105DTS	flagellar hook-associated
I862_07135	ENOG4105EEI	dihydropteroate synthase
I862_07140	ENOG4105EEI	dihydropteroate synthase
I862_07145	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
I862_07150	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
I862_07165	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
I862_07170	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
I862_07205	ENOG4105C22	threonyL-tRNA synthetase
I862_07210	ENOG4105C22	threonyL-tRNA synthetase
I862_07215	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
I862_07220	ENOG4105BZU	Histidine kinase
I862_07235	ENOG4105DA4	cytochrome c-type biogenesis protein
I862_07240	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
I862_07250	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
I862_07255	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
I862_07265	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
I862_07270	ENOG4107QQG	Dehydrogenase
I862_07275	ENOG4105J5G	Transferase hexapeptide repeat containing protein
I862_07280	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
I862_07290	ENOG4105EY8	ABC transporter
I862_07330	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
I862_07340	ENOG4105C2C	drug resistance transporter, Bcr CflA
I862_07370	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
I862_07425	ENOG4108ES9	ParB domain protein nuclease
I862_07545	ENOG4105CFG	Acts as a chaperone (By similarity)
I862_07555	ENOG4105K5G	30S ribosomal protein S21
I862_07600	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
I862_07605	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
I862_07610	ENOG4105GYT	Protein of unknown function (DUF1009)
I862_07615	ENOG4105CAT	Cytidine monophosphate kinase
I862_07620	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
I862_07635	ENOG4105CD8	aminopeptidase N
I862_07640	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
I862_07645	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)