locus-tag	class	description
D5125_00010	ENOG4105BZU	Histidine kinase
D5125_00020	ENOG4108JQC	penicillin-binding protein 1A
D5125_00030	ENOG4105BZU	Histidine kinase
D5125_00035	ENOG4105BZU	Histidine kinase
D5125_00050	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D5125_00065	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D5125_00070	ENOG41075W9	High frequency lysogenization protein HflD homolog
D5125_00075	ENOG4105KT5	UmuD protein
D5125_00080	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D5125_00090	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
D5125_00095	ENOG4105DB1	molybdopterin oxidoreductase
D5125_00105	ENOG4105C0D	helicase
D5125_00120	ENOG4105D3Q	Sugar transferase
D5125_00130	ENOG4107QN2	dihydrolipoyl dehydrogenase
D5125_00135	ENOG4105D65	subunit l
D5125_00140	ENOG4108ZE9	Monovalent cation H antiporter subunit C
D5125_00145	ENOG4107R4Z	monovalent cation h antiporter subunit d
D5125_00150	ENOG4105SC1	monovalent cation H antiporter subunit E
D5125_00155	ENOG4105W4C	monovalent cation H antiporter subunit F
D5125_00160	ENOG4105KJM	monovalent cation h antiporter subunit g
D5125_00180	ENOG4105BZU	Histidine kinase
D5125_00210	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_00215	ENOG4105BZU	Histidine kinase
D5125_00240	ENOG4107WUB	V-type ATPase 116 kDa subunit
D5125_00255	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D5125_00260	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
D5125_00265	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
D5125_00275	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D5125_00280	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
D5125_00285	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
D5125_00290	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
D5125_00295	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
D5125_00300	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D5125_00320	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5125_00325	ENOG4105C8S	subunit m
D5125_00335	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5125_00345	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5125_00350	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
D5125_00365	ENOG4105GKE	subunit e
D5125_00370	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5125_00375	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D5125_00380	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5125_00385	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D5125_00390	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D5125_00395	ENOG4105EYW	Ion transport protein
D5125_00420	ENOG4105D65	subunit l
D5125_00435	ENOG4105HC0	Na H antiporter
D5125_00440	ENOG4108ZE9	Monovalent cation H antiporter subunit C
D5125_00445	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D5125_00450	ENOG4105SC1	monovalent cation H antiporter subunit E
D5125_00455	ENOG41080TA	Multiple resistance and ph regulation protein f
D5125_00465	ENOG4105N1F	Hnh endonuclease
D5125_00495	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5125_00500	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5125_00510	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D5125_00515	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
D5125_00520	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D5125_00525	ENOG4108ZE9	Monovalent cation H antiporter subunit C
D5125_00530	ENOG4105HC0	Na H antiporter
D5125_00545	ENOG410684G	monovalent cation H antiporter subunit F
D5125_00550	ENOG4105SC1	monovalent cation H antiporter subunit E
D5125_00560	ENOG4105DHT	Metal Dependent Phosphohydrolase
D5125_00565	ENOG4108EC8	DNA internalization-related competence protein ComEC
D5125_00580	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
D5125_00605	ENOG4108YS0	lipoprotein YafL
D5125_00610	ENOG4105DZR	Type I site-specific deoxyribonuclease
D5125_00685	ENOG41060IM	Heme exporter protein
D5125_00695	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
D5125_00705	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
D5125_00730	ENOG4105CH2	amidohydrolase
D5125_00740	ENOG4108JQB	penicillin-binding protein 1C
D5125_00745	ENOG4105DN3	alpha-2-macroglobulin domain protein
D5125_00750	ENOG4105CZX	twitching motility protein
D5125_00765	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D5125_00775	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
D5125_00780	ENOG4105CDY	transcriptional regulatory protein
D5125_00785	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
D5125_00790	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
D5125_00795	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D5125_00800	ENOG4107YD3	Thioesterase
D5125_00805	ENOG4105E02	MotA TolQ exbB proton channel
D5125_00810	ENOG4105M8F	Biopolymer transport protein exbD tolR
D5125_00820	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
D5125_00825	ENOG4105KCK	Peptidoglycan-associated lipoprotein
D5125_00835	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
D5125_00840	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
D5125_00875	ENOG4105EI2	Pseudouridine synthase
D5125_00880	ENOG4105C03	ribonuclease
D5125_00890	ENOG4105BZU	Histidine kinase
D5125_00895	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D5125_00905	ENOG4105BZU	Histidine kinase
D5125_00915	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D5125_00920	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D5125_00925	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
D5125_00930	ENOG4108VZM	50s ribosomal protein L10
D5125_00935	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
D5125_00940	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
D5125_00945	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
D5125_00950	ENOG4105PM1	preprotein translocase subunit SecE
D5125_00960	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D5125_00985	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
D5125_00995	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
D5125_01000	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D5125_01005	ENOG4105VCC	30S ribosomal protein S21
D5125_01015	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
D5125_01020	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D5125_01030	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D5125_01035	ENOG41080IJ	Diacylglycerol kinase
D5125_01040	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
D5125_01050	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
D5125_01055	ENOG4108YXA	Membrane
D5125_01070	ENOG4105CSR	polyphosphate kinase 2
D5125_01075	ENOG4105E6M	Sulphatase-modifying factor protein
D5125_01080	ENOG4105EYW	Ion transport protein
D5125_01085	ENOG4108WIW	Aspartyl protease
D5125_01090	ENOG4105FAE	von Willebrand factor, type A
D5125_01095	ENOG4107QSV	RmuC domain protein
D5125_01115	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
D5125_01150	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D5125_01160	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_01170	ENOG4105BZU	Histidine kinase
D5125_01175	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_01180	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_01200	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
D5125_01205	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D5125_01210	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D5125_01215	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D5125_01240	ENOG4105C87	Aminotransferase class I and II
D5125_01245	ENOG4108NVR	Methyl-accepting chemotaxis
D5125_01270	ENOG4105C5Q	Transcriptional regulator
D5125_01285	ENOG4107YU2	histidine triad (hIT) protein
D5125_01295	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
D5125_01300	ENOG4107QMP	dna polymerase iii subunits gamma and tau
D5125_01310	ENOG4105EHZ	conserved protein UCP016719
D5125_01320	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D5125_01325	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D5125_01335	ENOG4108NVR	Methyl-accepting chemotaxis
D5125_01340	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D5125_01345	ENOG4108JA2	transcriptioN-repair coupling factor
D5125_01350	ENOG4105C0D	helicase
D5125_01365	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
D5125_01370	ENOG4105CEN	a g-specific adenine glycosylase
D5125_01375	ENOG4105CHC	glucokinase (EC 2.7.1.2)
D5125_01385	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D5125_01390	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D5125_01415	ENOG4105MKQ	Monovalent cation H antiporter subunit C
D5125_01420	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D5125_01425	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D5125_01435	ENOG4108JPZ	Monovalent cation H antiporter subunit D
D5125_01445	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
D5125_01455	ENOG4105ECY	inositol monophosphatase
D5125_01460	ENOG4107SC1	transglycosylase
D5125_01470	ENOG4105BZU	Histidine kinase
D5125_01475	ENOG4107YTP	response regulator receiver protein
D5125_01485	ENOG4105CBS	Chea signal transduction histidine kinase
D5125_01490	ENOG4105EEI	dihydropteroate synthase
D5125_01495	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D5125_01500	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
D5125_01505	ENOG4105HBR	Rna-binding protein
D5125_01510	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D5125_01515	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
D5125_01520	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D5125_01525	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D5125_01535	ENOG4105D00	flagellar biosynthetic protein flhB
D5125_01545	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
D5125_01550	ENOG4108JPW	Aminotransferase
D5125_01555	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
D5125_01565	ENOG4107QJE	Chromosome Partitioning Protein
D5125_01570	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D5125_01575	ENOG4105CBS	Chea signal transduction histidine kinase
D5125_01580	ENOG4108VYJ	response regulator receiver protein
D5125_01585	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D5125_01595	ENOG4105FZW	flagellar biosynthesis regulator FlhF
D5125_01600	ENOG4105D7B	Flagellar biosynthesis protein flha
D5125_01605	ENOG4105D00	flagellar biosynthetic protein flhB
D5125_01610	ENOG4108M3P	Membrane
D5125_01615	ENOG4105ERG	peptidase m48, ste24p
D5125_01620	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
D5125_01625	ENOG4105VS8	Flagellar biosynthetic protein fliq
D5125_01630	ENOG4105CN7	Flagellar biosynthetic protein FliP
D5125_01640	ENOG4105DD5	Flagellar motor switch protein
D5125_01645	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D5125_01660	ENOG4105C8N	cysteinyl-tRNA synthetase
D5125_01675	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
D5125_01680	ENOG4105EAQ	(twin-arginine translocation) pathway signal
D5125_01685	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
D5125_01695	ENOG41061WM	D-Alanyl-D-Alanine
D5125_01710	ENOG4105DUM	transcriptional regulator, lysR family
D5125_01715	ENOG4107QIJ	Aconitate hydratase 2
D5125_01730	ENOG4108JJB	ABC transporter
D5125_01755	ENOG4106RE7	Cytochrome
D5125_01785	ENOG4108VKQ	nitriC oxide reductase
D5125_01790	ENOG4105DSQ	Nitric oxide reductase
D5125_01795	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
D5125_01815	ENOG4108NWD	Cytochrome
D5125_01820	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D5125_01825	ENOG4105Y7H	Cytochrome
D5125_01835	ENOG4108ZGY	Transcriptional regulator (AsnC family)
D5125_01845	ENOG4108UMR	transcriptional regulator AsnC family
D5125_01875	ENOG4105CN1	protease
D5125_01885	ENOG41080RH	Thioredoxin
D5125_01895	ENOG4105EAM	Na Pi-cotransporter
D5125_01900	ENOG4105C1A	potassium transporter peripheral membrane
D5125_01905	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D5125_01915	ENOG4105C08	Histidine kinase
D5125_01920	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
D5125_01945	ENOG4105BZS	acriflavin resistance protein
D5125_01960	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
D5125_01965	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
D5125_01980	ENOG4105C3J	Cysteine desulfurase
D5125_02010	ENOG4107ZT5	Thiol disulfide interchange protein
D5125_02025	ENOG4108VCT	Sulfite exporter TauE/SafE
D5125_02060	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D5125_02075	ENOG4105CTB	Polyprenyl synthetase
D5125_02080	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
D5125_02090	ENOG4108ZAI	phosphatidylglycerophosphatase a
D5125_02095	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
D5125_02100	ENOG4107YIM	Involved in the transcription termination process (By similarity)
D5125_02105	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
D5125_02110	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
D5125_02125	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D5125_02135	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
D5125_02140	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D5125_02145	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_02150	ENOG4105BZU	Histidine kinase
D5125_02160	ENOG4107QQG	Dehydrogenase
D5125_02165	ENOG4105CDU	Replicative dna helicase
D5125_02170	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
D5125_02185	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
D5125_02190	ENOG4105DFG	type I secretion outer membrane protein
D5125_02195	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
D5125_02225	ENOG4108KU3	Integrase
D5125_02235	ENOG4107RDJ	Sulfotransferase
D5125_02245	ENOG4106QJ6	Integrase catalytic subunit
D5125_02265	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
D5125_02270	ENOG4108USZ	hydrogenase
D5125_02275	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
D5125_02280	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
D5125_02285	ENOG4105VF7	tolerance protein
D5125_02290	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
D5125_02295	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
D5125_02300	ENOG4108Z03	MAF-like protein
D5125_02305	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
D5125_02310	ENOG4108J5G	6-phosphogluconate dehydrogenase
D5125_02315	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
D5125_02325	ENOG4108Z0R	Transferase
D5125_02360	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
D5125_02365	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D5125_02370	ENOG4105BZU	Histidine kinase
D5125_02380	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_02395	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
D5125_02420	ENOG4107QR8	Thioredoxin
D5125_02425	ENOG4108R96	Methyltransferase, YaeB family
D5125_02465	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D5125_02470	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D5125_02475	ENOG4105VIE	preprotein translocase, subunit YajC
D5125_02485	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
D5125_02490	ENOG4106TD9	Diguanylate cyclase
D5125_02520	ENOG4107QZF	nitrite reductase NADPH large subunit
D5125_02525	ENOG4105E27	serine threonine protein kinase
D5125_02530	ENOG4105W3S	hemerythrin-like, metal-binding protein
D5125_02550	ENOG4105DVT	helicase
D5125_02565	ENOG4105BZ4	penicillin-binding protein
D5125_02595	ENOG4105CHW	UPF0052 protein
D5125_02605	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
D5125_02610	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
D5125_02625	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
D5125_02630	ENOG4105C58	cytochrome c oxidase accessory protein ccog
D5125_02685	ENOG4108F3G	Type I restriction-modification system, R subunit
D5125_02705	ENOG4105VV5	Plasmid stabilization system
D5125_02740	ENOG4105E0Y	RtcB Protein
D5125_02745	ENOG410756H	nucleotidyltransferase
D5125_02840	ENOG4108UUM	single-stranded DNA-binding protein
D5125_02885	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
D5125_02940	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_02960	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D5125_02965	ENOG4105E0F	Histidine kinase
D5125_02995	ENOG4105E3S	small subunit
D5125_03000	ENOG4108SX7	hmc operon protein 5
D5125_03035	ENOG4105BZU	Histidine kinase
D5125_03060	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D5125_03070	ENOG4107ZVW	dihydroneopterin aldolase
D5125_03075	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
D5125_03080	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
D5125_03085	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
D5125_03120	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D5125_03125	ENOG4105DR5	peptidase
D5125_03130	ENOG4108ESY	Metal dependent phosphohydrolase
D5125_03135	ENOG4105C94	Transporter
D5125_03150	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
D5125_03160	ENOG4105C8V	SAICAR synthetase
D5125_03180	ENOG4105CZX	twitching motility protein
D5125_03185	ENOG4105DFA	alanine racemase domain protein
D5125_03190	ENOG4105II7	pyrroline-5-carboxylate reductase
D5125_03195	ENOG4108VIA	integral membrane protein
D5125_03200	ENOG4105VZ9	UPF0235 protein
D5125_03210	ENOG4105W0E	50S ribosomal protein L33
D5125_03215	ENOG4105KDC	50s ribosomal protein l28
D5125_03220	ENOG4105W5Q	DNA repair protein (RadC
D5125_03225	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
D5125_03230	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
D5125_03235	ENOG4105CAS	nag kinase
D5125_03255	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D5125_03270	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
D5125_03280	ENOG4105CCT	upf0313 protein
D5125_03285	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
D5125_03290	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
D5125_03295	ENOG4105CUW	cytochrome C-TYPE protein
D5125_03305	ENOG4105GXZ	Ferredoxin-type protein NapH
D5125_03310	ENOG4108BGM	Quinol dehydrogenase periplasmic component
D5125_03320	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D5125_03340	ENOG4105BZU	Histidine kinase
D5125_03365	ENOG4105HF0	Membrane
D5125_03375	ENOG4105PBF	Anti-RNA polymerase sigma 70 factor
D5125_03385	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
D5125_03390	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D5125_03395	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
D5125_03405	ENOG4105W5Q	DNA repair protein (RadC
D5125_03410	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D5125_03465	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
D5125_03470	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
D5125_03475	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
D5125_03480	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
D5125_03485	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
D5125_03495	ENOG4107QX8	SPFH domain, Band 7 family protein
D5125_03515	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
D5125_03520	ENOG41081YB	ApbE family
D5125_03525	ENOG4105D7Z	glutathione synthase
D5125_03530	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D5125_03540	ENOG4105BZU	Histidine kinase
D5125_03545	ENOG4105DZB	Electron transport complex
D5125_03565	ENOG4108R3D	Electron transport complex
D5125_03570	ENOG4105DGN	Electron transport complex
D5125_03585	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
D5125_03610	ENOG4108IJ7	Glycine betaine
D5125_03615	ENOG4108HQS	Glycine betaine
D5125_03620	ENOG4105GIJ	Glycine betaine
D5125_03645	ENOG4105CHR	reductase
D5125_03650	ENOG4105CEY	Amp-dependent synthetase and ligase
D5125_03675	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
D5125_03680	ENOG4105FAW	cDP-glucose 4,6-dehydratase
D5125_03685	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D5125_03720	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D5125_03725	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D5125_03800	ENOG4105CMR	udp-glucose 4-epimerase
D5125_03840	ENOG4108KQJ	Type 11 methyltransferase
D5125_03890	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
D5125_03895	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D5125_03905	ENOG4105D2T	synthase
D5125_03910	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
D5125_03955	ENOG4105J5G	Transferase hexapeptide repeat containing protein
D5125_04030	ENOG4105CB5	ATP-dependent DNA helicase recG
D5125_04040	ENOG4105CY0	Metallo-Beta-Lactamase
D5125_04045	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
D5125_04050	ENOG4105C30	Nad-dependent epimerase dehydratase
D5125_04070	ENOG4107QKV	phosphomannomutase
D5125_04085	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5125_04095	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D5125_04115	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
D5125_04130	ENOG41090R7	Ferric uptake
D5125_04135	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D5125_04145	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D5125_04150	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D5125_04155	ENOG4105BZU	Histidine kinase
D5125_04170	ENOG4105BZU	Histidine kinase
D5125_04180	ENOG4105SYT	Methylenetetrahydrofolate reductase
D5125_04185	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
D5125_04190	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
D5125_04205	ENOG4105C8Y	Acetylornithine aminotransferase
D5125_04210	ENOG4105DBV	ornithine carbamoyltransferase
D5125_04220	ENOG4107QID	Threonine synthase
D5125_04225	ENOG4105CYW	agmatinase
D5125_04240	ENOG4105CSM	endonuclease III
D5125_04245	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
D5125_04250	ENOG41067XB	TonB family
D5125_04260	ENOG4109015	Biopolymer transport protein exbD tolR
D5125_04275	ENOG4105EYA	deoxyribonuclease
D5125_04300	ENOG4105E4G	Type IV pilus
D5125_04325	ENOG4108JQC	penicillin-binding protein 1A
D5125_04360	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_04365	ENOG4107QJE	Chromosome Partitioning Protein
D5125_04375	ENOG4108VYJ	response regulator receiver protein
D5125_04385	ENOG4105CBS	Chea signal transduction histidine kinase
D5125_04390	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_04395	ENOG4108V3W	Chemotaxis protein, CheW
D5125_04400	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_04405	ENOG4108V3W	Chemotaxis protein, CheW
D5125_04410	ENOG4105BZU	Histidine kinase
D5125_04415	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
D5125_04420	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D5125_04425	ENOG4105DC1	bifunctional purine biosynthesis protein purh
D5125_04430	ENOG4105C12	Phosphoribosylglycinamide synthetase
D5125_04435	ENOG4105GPY	SprT protein
D5125_04445	ENOG4108Z9W	Outer membrane porin
D5125_04450	ENOG4105CNG	UPF0061 protein
D5125_04455	ENOG4108RCM	Nitroreductase
D5125_04465	ENOG4107PAI	alpha helical protein
D5125_04470	ENOG4105CZX	twitching motility protein
D5125_04480	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
D5125_04495	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
D5125_04505	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
D5125_04515	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
D5125_04530	ENOG4107RAQ	aminopeptidase
D5125_04535	ENOG4105D0A	hydroxylase
D5125_04540	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
D5125_04545	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D5125_04550	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D5125_04590	ENOG4105BZU	Histidine kinase
D5125_04595	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D5125_04620	ENOG4107RDJ	Sulfotransferase
D5125_04635	ENOG4108UK5	Transposase
D5125_04665	ENOG4108EX3	reductase
D5125_04675	ENOG4106RE7	Cytochrome
D5125_04680	ENOG4108Z33	Thiol disulfide Interchange Protein
D5125_04690	ENOG4105BZU	Histidine kinase
D5125_04695	ENOG4105C4R	Atp-dependent dna helicase
D5125_04710	ENOG4105VEQ	Cold shock protein
D5125_04720	ENOG4108YZY	peptidylprolyl cis-trans isomerase
D5125_04745	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
D5125_04755	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
D5125_04760	ENOG4108IUZ	ABC transporter
D5125_04765	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D5125_04770	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
D5125_04775	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
D5125_04785	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
D5125_04790	ENOG4105YHU	PTS system
D5125_04795	ENOG41080Z8	PHOSPHOCARRIER protein
D5125_04820	ENOG4108I0Y	(ABC) transporter
D5125_04835	ENOG4108ZAF	Molybdopterin
D5125_04840	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D5125_04850	ENOG4105BZU	Histidine kinase
D5125_04855	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_04860	ENOG4105BZU	Histidine kinase
D5125_04880	ENOG4105CGK	Exodeoxyribonuclease III
D5125_04885	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D5125_04890	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
D5125_04900	ENOG4105EPW	hflc protein
D5125_04905	ENOG4107QJR	hflk protein
D5125_04910	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D5125_04915	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
D5125_04955	ENOG4108URH	decarboxylase
D5125_04960	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D5125_04995	ENOG4108Z86	Glutamine amidotransferase
D5125_05010	ENOG4105C02	permease
D5125_05015	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
D5125_05025	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
D5125_05030	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
D5125_05035	ENOG4105BZU	Histidine kinase
D5125_05040	ENOG4107XNE	ABC transporter, periplasmic molybdate-binding protein
D5125_05045	ENOG4105DHP	deoxycytidine triphosphate deaminase
D5125_05055	ENOG4105BZU	Histidine kinase
D5125_05060	ENOG4105BZU	Histidine kinase
D5125_05065	ENOG4108NVR	Methyl-accepting chemotaxis
D5125_05090	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
D5125_05095	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D5125_05110	ENOG4106WTF	Glycosyl transferase, family 2
D5125_05120	ENOG4105BZ1	(ABC) transporter
D5125_05140	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D5125_05145	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D5125_05150	ENOG4105N21	Membrane
D5125_05155	ENOG4105CUT	histidyl-tRNA synthetase
D5125_05170	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
D5125_05175	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D5125_05185	ENOG4105WVQ	Fe-S assembly protein IscX
D5125_05190	ENOG4108ZIT	Ferredoxin, 2FE-2S
D5125_05195	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
D5125_05205	ENOG4108Z4V	iron-sulfur cluster assembly
D5125_05210	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
D5125_05215	ENOG4105C3J	Cysteine desulfurase
D5125_05220	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
D5125_05230	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
D5125_05235	ENOG4105ECY	inositol monophosphatase
D5125_05250	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
D5125_05255	ENOG4105D3G	Pseudouridine synthase
D5125_05270	ENOG4105BZU	Histidine kinase
D5125_05275	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
D5125_05280	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
D5125_05315	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
D5125_05320	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
D5125_05325	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
D5125_05330	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_05335	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_05345	ENOG4105K89	arsenate reductase
D5125_05350	ENOG4105CS1	NAD(P)H quinone oxidoreductase
D5125_05360	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
D5125_05365	ENOG4105YES	addiction module antidote protein
D5125_05370	ENOG4105VUH	addiction module killer protein
D5125_05385	ENOG4105EKQ	RNA-directed DNA polymerase
D5125_05405	ENOG4107RDJ	Sulfotransferase
D5125_05420	ENOG4105EKQ	RNA-directed DNA polymerase
D5125_05500	ENOG4107RDJ	Sulfotransferase
D5125_05525	ENOG4105QNJ	serralysin (EC 3.4.24.40)
D5125_05535	ENOG4105EY8	ABC transporter
D5125_05550	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D5125_05605	ENOG4108RT7	Glycosyl transferase, family 2
D5125_05625	ENOG4108JJ6	Type I secretion system ATPase
D5125_05645	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D5125_05650	ENOG4107S7U	Sulfide dehydrogenase
D5125_05655	ENOG4105MW3	Cytochrome
D5125_05660	ENOG4105CUW	cytochrome C-TYPE protein
D5125_05665	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
D5125_05675	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
D5125_05685	ENOG4105DJV	ribulose-phosphate 3-epimerase
D5125_05695	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D5125_05700	ENOG4105D9P	serine threonine protein kinase
D5125_05710	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
D5125_05720	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
D5125_05750	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
D5125_05755	ENOG4108NEV	two component transcriptional regulator, LytTR family
D5125_05765	ENOG4105CH7	arginosuccinase
D5125_05780	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D5125_05795	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D5125_05800	ENOG4105CT0	Protein of unknown function, DUF484
D5125_05805	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D5125_05810	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
D5125_05825	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_05830	ENOG4105BZU	Histidine kinase
D5125_05845	ENOG4108JUA	Transcriptional regulator
D5125_05855	ENOG4105D05	Receptor
D5125_05865	ENOG4107ENK	receptor
D5125_05870	ENOG4105CKK	Glycosyl transferase, family 2
D5125_05880	ENOG4105DTN	riboflavin biosynthesis protein ribF
D5125_05885	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D5125_05895	ENOG4105BZU	Histidine kinase
D5125_05905	ENOG4105EAH	synthase
D5125_05925	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D5125_05970	ENOG4107QMH	DNA methylase
D5125_05990	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D5125_05995	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D5125_06000	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D5125_06010	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D5125_06015	ENOG4105DZP	Membrane-associated zinc metalloprotease
D5125_06025	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
D5125_06030	ENOG4105KNE	Phosphatidate cytidylyltransferase
D5125_06035	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D5125_06040	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
D5125_06050	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
D5125_06055	ENOG4105CE9	30S ribosomal protein S2
D5125_06060	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
D5125_06065	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
D5125_06075	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D5125_06080	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
D5125_06085	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D5125_06090	ENOG4108ZP8	Acetolactate synthase small subunit
D5125_06095	ENOG4105C7K	acetolactate synthase
D5125_06100	ENOG4105C3G	gtp-binding protein
D5125_06115	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_06120	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D5125_06125	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
D5125_06130	ENOG4105BZU	Histidine kinase
D5125_06145	ENOG4107QJE	Chromosome Partitioning Protein
D5125_06150	ENOG4108V3W	Chemotaxis protein, CheW
D5125_06155	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_06160	ENOG4108V3W	Chemotaxis protein, CheW
D5125_06165	ENOG4105CBS	Chea signal transduction histidine kinase
D5125_06170	ENOG4108VYJ	response regulator receiver protein
D5125_06175	ENOG4105C1J	atp-dependent rna helicase
D5125_06180	ENOG4105CJB	Exodeoxyribonuclease I
D5125_06195	ENOG4105PWE	CRISPR-associated protein cas2
D5125_06200	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
D5125_06215	ENOG4108Y7V	CRISPR-associated protein, Cse3 family
D5125_06225	ENOG4108VWQ	crispr-associated protein
D5125_06230	ENOG41060M0	Crispr-associated protein, cse4 family
D5125_06245	ENOG4105DTT	CRISPR-associated helicase, cas3
D5125_06250	ENOG4105Y75	tpr repeat protein
D5125_06255	ENOG4105E33	succinate dehydrogenase
D5125_06260	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
D5125_06275	ENOG4105C6K	Malic enzyme
D5125_06285	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5125_06290	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
D5125_06295	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D5125_06300	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
D5125_06310	ENOG4105DFU	Cell wall formation (By similarity)
D5125_06315	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
D5125_06320	ENOG4108KF1	Membrane
D5125_06325	ENOG4108VYJ	response regulator receiver protein
D5125_06330	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
D5125_06335	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
D5125_06340	ENOG4105DWF	phosphomethylpyrimidine kinase
D5125_06365	ENOG4105BZU	Histidine kinase
D5125_06370	ENOG4105BZU	Histidine kinase
D5125_06390	ENOG4105BZU	Histidine kinase
D5125_06395	ENOG4105BZU	Histidine kinase
D5125_06400	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
D5125_06405	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
D5125_06415	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
D5125_06420	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D5125_06430	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D5125_06435	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D5125_06440	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
D5125_06445	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
D5125_06460	ENOG4105EHM	Aminoglycoside phosphotransferase
D5125_06470	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
D5125_06475	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
D5125_06485	ENOG4105C0P	Mg chelatase subunit ChlI
D5125_06490	ENOG4105W0Z	cytoplasmic protein
D5125_06495	ENOG4108YZA	Nitrogen regulatory protein pii
D5125_06510	ENOG4105VBA	Cytochrome
D5125_06520	ENOG4105C3R	Methionine synthase
D5125_06570	ENOG4105C0H	protease
D5125_06595	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D5125_06605	ENOG4105D49	3-dehydroquinate synthase
D5125_06640	ENOG4107R3N	Filamentation induced by cAMP protein fic
D5125_06675	ENOG4105BZU	Histidine kinase
D5125_06680	ENOG4105BZU	Histidine kinase
D5125_06720	ENOG4105D6Z	AFG1 family ATPase
D5125_06725	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
D5125_06735	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D5125_06765	ENOG4105BZU	Histidine kinase
D5125_06770	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
D5125_06800	ENOG4108V06	Glutathione peroxidase
D5125_06815	ENOG4108XDN	Transcriptional regulator
D5125_06820	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D5125_06830	ENOG4105C8H	hydrogenase maturation protein Hypf
D5125_06845	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
D5125_06850	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
D5125_06855	ENOG4105CB5	ATP-dependent DNA helicase recG
D5125_06865	ENOG4105KME	endoribonuclease L-psp
D5125_06870	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D5125_06875	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
D5125_06880	ENOG4105D1S	lipid A biosynthesis
D5125_06885	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
D5125_06890	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D5125_06905	ENOG4107TAE	Glycosyl transferase (Group 1
D5125_06920	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
D5125_06925	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D5125_06935	ENOG4107TUY	Histidine kinase
D5125_06940	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5125_06975	ENOG4105YES	addiction module antidote protein
D5125_06985	ENOG410631X	Hydrogenase expression formation protein
D5125_06995	ENOG4108USZ	hydrogenase
D5125_07000	ENOG4105DPX	Hydrogenase, large subunit
D5125_07005	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
D5125_07010	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
D5125_07015	ENOG4105E3S	small subunit
D5125_07025	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
D5125_07050	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
D5125_07055	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
D5125_07065	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D5125_07075	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D5125_07080	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D5125_07085	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
D5125_07090	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
D5125_07095	ENOG4105CPF	Cell wall formation (By similarity)
D5125_07100	ENOG4105D4A	Cell wall formation (By similarity)
D5125_07110	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D5125_07115	ENOG4105CNI	cell division protein FtsW
D5125_07120	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
D5125_07125	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
D5125_07130	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
D5125_07135	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D5125_07140	ENOG4105CJN	penicillin-binding protein
D5125_07145	ENOG4106932	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D5125_07150	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
D5125_07155	ENOG4108V6E	Cell division protein mraZ
D5125_07200	ENOG4108YZY	peptidylprolyl cis-trans isomerase
D5125_07205	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D5125_07210	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
D5125_07220	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D5125_07225	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D5125_07230	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D5125_07235	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D5125_07240	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
D5125_07250	ENOG4105FA0	parb-like partition protein
D5125_07255	ENOG4107QJE	Chromosome Partitioning Protein
D5125_07260	ENOG4105BZU	Histidine kinase
D5125_07265	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
D5125_07270	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
D5125_07275	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D5125_07285	ENOG4105F8C	transglutaminase domain-containing protein
D5125_07290	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D5125_07295	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D5125_07300	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D5125_07305	ENOG4105VG0	50S ribosomal protein l34
D5125_07310	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D5125_07315	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
D5125_07320	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
D5125_07325	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D5125_07335	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
D5125_07340	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
D5125_07345	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D5125_07360	ENOG4105C5F	glutamine synthetase
D5125_07370	ENOG4105CUX	Signal transduction histidine kinase
D5125_07375	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5125_07390	ENOG4105D82	Glutamate dehydrogenase
D5125_07400	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D5125_07405	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
D5125_07410	ENOG4108UJU	UPF0301 protein
D5125_07420	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
D5125_07425	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
D5125_07440	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
D5125_07445	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
D5125_07460	ENOG4107QNR	UPF0135 protein
D5125_07465	ENOG4105C0H	protease
D5125_07470	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D5125_07485	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
D5125_07490	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
D5125_07495	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D5125_07500	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D5125_07505	ENOG4108UJV	acyl-CoA thioesterase i
D5125_07520	ENOG4105IFJ	Histidine kinase
D5125_07525	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D5125_07550	ENOG4107PE3	Mammalian cell entry related domain protein
D5125_07555	ENOG4105CY3	ABC transporter, permease
D5125_07560	ENOG4105DHJ	ABC, transporter
D5125_07565	ENOG4105BZG	amino acid carrier protein
D5125_07640	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D5125_07655	ENOG4107S21	permease
D5125_07670	ENOG4108S0S	Nucleotidyl transferase
D5125_07690	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
D5125_07695	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
D5125_07705	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D5125_07710	ENOG4105DJ0	Poly(A) Polymerase
D5125_07715	ENOG4105F8J	Adenylate Guanylate cyclase
D5125_07745	ENOG41060JE	PilT protein domain protein
D5125_07755	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D5125_07760	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D5125_07765	ENOG4105E50	uracil-dna glycosylase
D5125_07770	ENOG4105WH1	Two component transcriptional regulator luxr family
D5125_07785	ENOG4105C5H	ABC transporter
D5125_07790	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D5125_07810	ENOG4105CRQ	synthase (Component I)
D5125_07815	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_07825	ENOG4105CD3	dihydroorotase
D5125_07830	ENOG4108KE4	O-methyltransferase
D5125_07835	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D5125_07840	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
D5125_07845	ENOG4105CUZ	uba thif-type nad fad binding protein
D5125_07855	ENOG4105C0D	helicase
D5125_07860	ENOG4105NI8	Cytosine-specific methyltransferase
D5125_07910	ENOG4107QN2	dihydrolipoyl dehydrogenase
D5125_07975	ENOG4107QSN	dihydrolipoamide acetyltransferase
D5125_07980	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
D5125_08000	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
D5125_08005	ENOG4105M2J	Glutaredoxin
D5125_08015	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D5125_08020	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D5125_08030	ENOG4108RPN	Protein smg homolog
D5125_08035	ENOG4105C79	DNA protecting protein DprA
D5125_08045	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D5125_08050	ENOG4108VYJ	response regulator receiver protein
D5125_08070	ENOG41069P5	Protein slyX homolog
D5125_08080	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_08085	ENOG4105BZU	Histidine kinase
D5125_08090	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D5125_08095	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
D5125_08100	ENOG4105I03	Flagellin
D5125_08105	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D5125_08115	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D5125_08130	ENOG4107S74	Lysophospholipid transporter LplT
D5125_08135	ENOG4105CEY	Amp-dependent synthetase and ligase
D5125_08140	ENOG4108JUA	Transcriptional regulator
D5125_08145	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
D5125_08150	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
D5125_08160	ENOG4105EHG	Permease protein
D5125_08165	ENOG4105D5T	phosphonate abc transporter
D5125_08175	ENOG4105BZU	Histidine kinase
D5125_08200	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
D5125_08205	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
D5125_08210	ENOG4105C4R	Atp-dependent dna helicase
D5125_08220	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_08225	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D5125_08250	ENOG41081QV	Universal stress protein
D5125_08255	ENOG4105DSY	exodeoxyribonuclease V, gamma
D5125_08260	ENOG4107QKA	exodeoxyribonuclease V beta
D5125_08265	ENOG4107QYX	exodeoxyribonuclease v alpha
D5125_08275	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
D5125_08280	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
D5125_08305	ENOG4106RHG	Yeca family
D5125_08310	ENOG4105D7A	ATP-binding protein
D5125_08320	ENOG4105CBS	Chea signal transduction histidine kinase
D5125_08325	ENOG4105CBS	Chea signal transduction histidine kinase
D5125_08330	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_08335	ENOG4108V3W	Chemotaxis protein, CheW
D5125_08340	ENOG4105M3Z	response regulator
D5125_08345	ENOG4108UNF	response regulator
D5125_08360	ENOG4105BZU	Histidine kinase
D5125_08365	ENOG4105C7B	Threonine dehydratase
D5125_08370	ENOG4105E66	phosphoriboisomerase A
D5125_08380	ENOG4105BZU	Histidine kinase
D5125_08385	ENOG4105C2X	Arabinose 5-phosphate isomerase
D5125_08410	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
D5125_08415	ENOG4105EV9	Alpha Beta Hydrolase
D5125_08425	ENOG4105CDH	Citrulline--aspartate ligase
D5125_08430	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D5125_08435	ENOG4107QSA	Oxaloacetate decarboxylase
D5125_08440	ENOG4107QHF	type ii secretion system protein e
D5125_08445	ENOG4105CPI	Metal Dependent Phosphohydrolase
D5125_08450	ENOG4105C2M	dna polymerase I
D5125_08485	ENOG4107R88	Chemotaxis protein (CheV)
D5125_08490	ENOG4105BZU	Histidine kinase
D5125_08495	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
D5125_08500	ENOG4108ZC9	flagellar basal-body rod protein flgc
D5125_08510	ENOG410822I	Flagellar hook capping protein
D5125_08515	ENOG4105BZE	flagellar hook protein, FlgE
D5125_08520	ENOG4108KPB	Flagellar basal-body rod protein FlgF
D5125_08530	ENOG4105C03	ribonuclease
D5125_08540	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
D5125_08545	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D5125_08555	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
D5125_08560	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
D5125_08565	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
D5125_08570	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
D5125_08575	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D5125_08590	ENOG4105D06	uba thif-type nad fad binding protein
D5125_08595	ENOG4107Y49	methyltransferase
D5125_08600	ENOG4106TD9	Diguanylate cyclase
D5125_08620	ENOG4105G9V	cytochrome C
D5125_08625	ENOG4105CA0	peroxidase
D5125_08635	ENOG4105CUW	cytochrome C-TYPE protein
D5125_08645	ENOG4105W3S	hemerythrin-like, metal-binding protein
D5125_08660	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
D5125_08665	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
D5125_08670	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
D5125_08675	ENOG4105DFF	Rod shape-determining protein mreb
D5125_08695	ENOG4105CJN	penicillin-binding protein
D5125_08700	ENOG4105CNI	cell division protein FtsW
D5125_08705	ENOG4105CVE	Lytic murein transglycosylase
D5125_08715	ENOG4105DZ1	carboxypeptidase
D5125_08720	ENOG4105F0I	Aminotransferase
D5125_08725	ENOG4108Z43	UPF0250 protein
D5125_08730	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D5125_08735	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
D5125_08740	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D5125_08755	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
D5125_08760	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D5125_08765	ENOG4105M00	molybdopterin converting factor, subunit 1
D5125_08770	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
D5125_08775	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
D5125_08780	ENOG4105Q9Y	Universal stress protein
D5125_08785	ENOG4105E0C	molybdate abc transporter
D5125_08790	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
D5125_08795	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D5125_08800	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
D5125_08805	ENOG4105BZU	Histidine kinase
D5125_08815	ENOG4105CHM	Aminotransferase
D5125_08820	ENOG4105D6E	homoserine dehydrogenase
D5125_08830	ENOG4105K5M	30s ribosomal protein S16
D5125_08835	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
D5125_08840	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
D5125_08845	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
D5125_08855	ENOG4105BZU	Histidine kinase
D5125_08860	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D5125_08865	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
D5125_08870	ENOG4105EIX	cytochrome c1
D5125_08875	ENOG4107MKT	Stringent starvation protein a
D5125_08880	ENOG4105KB2	stringent starvation protein b
D5125_08895	ENOG4105BZS	acriflavin resistance protein
D5125_08900	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
D5125_08905	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D5125_08920	ENOG4105C59	p-type ATPase
D5125_08925	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
D5125_08930	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
D5125_08935	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
D5125_08945	ENOG4105BZU	Histidine kinase
D5125_08955	ENOG4105CH5	extracellular solute-binding protein, family 7
D5125_08960	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
D5125_08985	ENOG4105DFS	Conserved Protein
D5125_08990	ENOG4107XZC	Restriction modification system DNA (Specificity
D5125_08995	ENOG4105CB5	ATP-dependent DNA helicase recG
D5125_09010	ENOG4105ETX	regulatoR
D5125_09020	ENOG4105DUM	transcriptional regulator, lysR family
D5125_09035	ENOG4105C0H	protease
D5125_09105	ENOG4105C0H	protease
D5125_09200	ENOG4105CPC	Aldo Keto reductase
D5125_09205	ENOG4105BZU	Histidine kinase
D5125_09210	ENOG4105BZU	Histidine kinase
D5125_09215	ENOG4105CPI	Metal Dependent Phosphohydrolase
D5125_09225	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D5125_09230	ENOG4105D58	Diguanylate phosphodiesterase
D5125_09240	ENOG4105BZU	Histidine kinase
D5125_09245	ENOG4105CTQ	phosphohexokinase
D5125_09250	ENOG4105C5H	ABC transporter
D5125_09265	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_09270	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D5125_09275	ENOG4108KTQ	Methyltransferase
D5125_09280	ENOG4105CBS	Chea signal transduction histidine kinase
D5125_09285	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5125_09290	ENOG4105BZU	Histidine kinase
D5125_09310	ENOG4105F5W	AtP-binding protein
D5125_09315	ENOG4105D70	Integrase catalytic subunit
D5125_09370	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D5125_09420	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
D5125_09430	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D5125_09440	ENOG4105F0N	pyrophosphate phospho-hydrolase
D5125_09450	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D5125_09470	ENOG4105CV1	Transketolase (EC 2.2.1.1)
D5125_09480	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D5125_09485	ENOG4105BZA	Phosphoglycerate kinase
D5125_09490	ENOG4105CA9	Pyruvate kinase
D5125_09495	ENOG4105D2N	Aldolase
D5125_09510	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
D5125_09530	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D5125_09535	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D5125_09540	ENOG4105BZN	citrate synthase
D5125_09545	ENOG4105C6K	Malic enzyme
D5125_09560	ENOG4105VFB	Binds the 23S rRNA (By similarity)
D5125_09565	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
D5125_09570	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D5125_09595	ENOG4105DZP	Membrane-associated zinc metalloprotease
D5125_09600	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
D5125_09615	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
D5125_09655	ENOG4105VV5	Plasmid stabilization system
D5125_09670	ENOG41082AG	Plasmid maintenance system antidote protein
D5125_09680	ENOG4105KHS	type IV fimbrial pilin protein
D5125_09715	ENOG41082AG	Plasmid maintenance system antidote protein
D5125_09740	ENOG4108RH0	Crea protein
D5125_09745	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D5125_09750	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D5125_09755	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D5125_09760	ENOG41080ET	plasmid maintenance system killer protein
D5125_09830	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
D5125_09855	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
D5125_09860	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
D5125_09865	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
D5125_09870	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
D5125_09880	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
D5125_09905	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
D5125_09915	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
D5125_09935	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
D5125_09940	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
D5125_09945	ENOG4105C5E	polysaccharide biosynthesis protein
D5125_09955	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
D5125_09960	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
D5125_09970	ENOG4106H78	methyltransferase
D5125_09975	ENOG4105C1V	Peptidase, M16
D5125_09985	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D5125_09990	ENOG4105CAK	Cell division ATP-binding protein ftsE
D5125_09995	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
D5125_10000	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_10005	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D5125_10025	ENOG4105F5W	AtP-binding protein
D5125_10030	ENOG4105D70	Integrase catalytic subunit
D5125_10045	ENOG4108HFV	
D5125_10050	ENOG4107QTH	restriction modification system DNA specificity domain
D5125_10060	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
D5125_10065	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
D5125_10090	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
D5125_10095	ENOG4105KNY	Microcompartments protein
D5125_10115	ENOG4105DUM	transcriptional regulator, lysR family
D5125_10120	ENOG4108PQP	glycosyl transferase group 1
D5125_10140	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
D5125_10145	ENOG4105BZU	Histidine kinase
D5125_10160	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
D5125_10175	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
D5125_10185	ENOG41080XP	Cbs domain
D5125_10205	ENOG4107QJE	Chromosome Partitioning Protein
D5125_10220	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D5125_10225	ENOG4105C6K	Malic enzyme
D5125_10245	ENOG4105CZX	twitching motility protein
D5125_10255	ENOG4105VEQ	Cold shock protein
D5125_10260	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
D5125_10265	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D5125_10270	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
D5125_10275	ENOG4105BZU	Histidine kinase
D5125_10280	ENOG4105BZU	Histidine kinase
D5125_10310	ENOG4105E18	UPF0276 protein
D5125_10320	ENOG4109045	doxx family
D5125_10325	ENOG4105BZU	Histidine kinase
D5125_10330	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_10335	ENOG4107R88	Chemotaxis protein (CheV)
D5125_10340	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
D5125_10345	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D5125_10350	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
D5125_10360	ENOG4105BZU	Histidine kinase
D5125_10380	ENOG4105DJ4	phosphatidylserine decarboxylase
D5125_10390	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D5125_10395	ENOG4105W8H	transhydrogenase (subunit alpha
D5125_10400	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D5125_10425	ENOG4105I03	Flagellin
D5125_10435	ENOG41063QE	flagellar protein FlaG
D5125_10440	ENOG4105DTS	flagellar hook-associated
D5125_10445	ENOG4105MQ3	flagellar protein FliS
D5125_10455	ENOG4105CRE	cytochrome C
D5125_10460	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D5125_10475	ENOG4107QZM	n-acetylglutamate synthase
D5125_10480	ENOG4105CWC	Acetylornithine deacetylase
D5125_10485	ENOG4105C01	Dihydroxy-acid dehydratase
D5125_10490	ENOG4105CFH	Aspartokinase
D5125_10495	ENOG4105BZG	amino acid carrier protein
D5125_10500	ENOG4105D64	Mechanosensitive ion channel
D5125_10515	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
D5125_10520	ENOG4105KRP	Plasmid stabilization system
D5125_10525	ENOG4105YAJ	CopG Arc MetJ
D5125_10530	ENOG4105DFP	Integrase
D5125_10550	ENOG4108UUM	single-stranded DNA-binding protein
D5125_10580	ENOG4105W5Q	DNA repair protein (RadC
D5125_10590	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D5125_10600	ENOG4108MN8	Membrane
D5125_10610	ENOG4105VFU	Rna-binding protein
D5125_10615	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
D5125_10625	ENOG4105WMR	Protein CrcB homolog
D5125_10650	ENOG4105M85	Bola protein
D5125_10655	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D5125_10660	ENOG4108UPT	UPF0178 protein
D5125_10665	ENOG4105K63	Thioredoxin
D5125_10670	ENOG4105D52	delta-aminolevulinic acid dehydratase
D5125_10690	ENOG4105CSR	polyphosphate kinase 2
D5125_10695	ENOG4107IX6	phosphate transport regulator
D5125_10700	ENOG4105CJ3	phosphate transporter
D5125_10715	ENOG4105BZU	Histidine kinase
D5125_10720	ENOG4105BZU	Histidine kinase
D5125_10725	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
D5125_10730	ENOG4105C31	Tryptophanyl-tRNA synthetase
D5125_10735	ENOG4108Z4T	Peptidase M50
D5125_10740	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
D5125_10745	ENOG4105DB7	PHP domain protein
D5125_10755	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
D5125_10760	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
D5125_10765	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
D5125_10770	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
D5125_10775	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
D5125_10780	ENOG4105CHV	Transcription elongation factor NusA
D5125_10785	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
D5125_10795	ENOG4105VDB	UPF0125 protein
D5125_10800	ENOG4108Z1B	Cyclase dehydrase
D5125_10805	ENOG4105C8J	)-transporter
D5125_10810	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
D5125_10820	ENOG4105DFP	Integrase
D5125_10825	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
D5125_10830	ENOG4108Z4T	Peptidase M50
D5125_10835	ENOG4105C31	Tryptophanyl-tRNA synthetase
D5125_10840	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
D5125_10845	ENOG4105BZU	Histidine kinase
D5125_10850	ENOG4105BZU	Histidine kinase
D5125_10880	ENOG41090HT	Inherit from COG: transposase
D5125_10885	ENOG4105CB5	ATP-dependent DNA helicase recG
D5125_10905	ENOG4107QVM	von Willebrand factor, type A
D5125_10925	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D5125_10930	ENOG4105BZU	Histidine kinase
D5125_10945	ENOG4105K63	Thioredoxin
D5125_10950	ENOG4105EGS	Mechanosensitive ion channel
D5125_10955	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
D5125_10960	ENOG4108PXI	ErfK YbiS YcfS YnhG
D5125_10980	ENOG4105C59	p-type ATPase
D5125_11040	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D5125_11050	ENOG4108YZA	Nitrogen regulatory protein pii
D5125_11055	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D5125_11060	ENOG4105F0R	Cytidylyltransferase
D5125_11075	ENOG4105E2X	shikimate dehydrogenase
D5125_11100	ENOG4107QUT	magnesium and cobalt transport protein CorA
D5125_11115	ENOG4107RK2	ADP-ribose diphosphatase NudE
D5125_11140	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
D5125_11145	ENOG4105C1J	atp-dependent rna helicase
D5125_11150	ENOG4105K63	Thioredoxin
D5125_11155	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
D5125_11175	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
D5125_11180	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
D5125_11195	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_11200	ENOG4108K3Z	AraC family transcriptional regulator
D5125_11205	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D5125_11215	ENOG4105BZU	Histidine kinase
D5125_11220	ENOG4105WH1	Two component transcriptional regulator luxr family
D5125_11225	ENOG41085GJ	domain protein
D5125_11230	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
D5125_11240	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
D5125_11245	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
D5125_11320	ENOG4105D70	Integrase catalytic subunit
D5125_11325	ENOG4105F5W	AtP-binding protein
D5125_11345	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
D5125_11390	ENOG41086B8	CoB-CoM heterodisulfide reductase
D5125_11395	ENOG4105E33	succinate dehydrogenase
D5125_11405	ENOG4105EWK	phytoene
D5125_11415	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D5125_11420	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
D5125_11425	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D5125_11430	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D5125_11435	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
D5125_11440	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
D5125_11450	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
D5125_11455	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D5125_11460	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
D5125_11470	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
D5125_11475	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
D5125_11485	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
D5125_11490	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
D5125_11495	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
D5125_11500	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D5125_11505	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
D5125_11510	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D5125_11515	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
D5125_11520	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
D5125_11525	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
D5125_11535	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
D5125_11540	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
D5125_11545	ENOG41067V7	50S ribosomal protein L36
D5125_11550	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D5125_11555	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
D5125_11560	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
D5125_11565	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D5125_11570	ENOG4108ZT0	50S ribosomal protein l17
D5125_11590	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
D5125_11595	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
D5125_11600	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
D5125_11605	ENOG4105C1A	potassium transporter peripheral membrane
D5125_11610	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5125_11615	ENOG4105ES5	Histidine kinase
D5125_11625	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
D5125_11630	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
D5125_11665	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
D5125_11670	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
D5125_11675	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
D5125_11690	ENOG4107QHF	type ii secretion system protein e
D5125_11695	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D5125_11725	ENOG41080HT	Transcriptional regulator, arsr family
D5125_11730	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D5125_11735	ENOG41063SB	peptidase
D5125_11740	ENOG4105CN1	protease
D5125_11745	ENOG4105PXI	polysaccharide deacetylase
D5125_11750	ENOG4107S0N	DJ-1 family
D5125_11760	ENOG4105CE1	Ferrous iron transport protein b
D5125_11770	ENOG4108Z9W	Outer membrane porin
D5125_11790	ENOG4105C8T	Leucyl-tRNA synthetase
D5125_11885	ENOG4105MPD	Cytochrome
D5125_11890	ENOG4105MJ2	Competence protein
D5125_11895	ENOG4105CD3	dihydroorotase
D5125_11900	ENOG4105CXT	aspartate transcarbamylase
D5125_11915	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
D5125_11925	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D5125_11930	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
D5125_11945	ENOG4105DSJ	YicC domain protein
D5125_11950	ENOG4105DFP	Integrase
D5125_11970	ENOG4105F5W	AtP-binding protein
D5125_12035	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
D5125_12070	ENOG4108Z6B	deaminase
D5125_12075	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
D5125_12080	ENOG4105BZ8	glutamate synthase
D5125_12120	ENOG4108JUA	Transcriptional regulator
D5125_12125	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5125_12130	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
D5125_12135	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
D5125_12140	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
D5125_12150	ENOG4108JIR	Flagellum-specific ATP synthase
D5125_12175	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D5125_12180	ENOG4107RZZ	dna polymerase iii epsilon subunit
D5125_12185	ENOG4108IJF	Heavy metal efflux pump, CzcA
D5125_12215	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
D5125_12220	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D5125_12225	ENOG4105Y3E	Modulates RecA activity (By similarity)
D5125_12235	ENOG4105PW4	Sugar fermentation stimulation protein homolog
D5125_12245	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D5125_12255	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D5125_12260	ENOG4105DUM	transcriptional regulator, lysR family
D5125_12265	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
D5125_12280	ENOG4105E1F	short-chain dehydrogenase reductase
D5125_12285	ENOG4105BZM	domain protein
D5125_12375	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
D5125_12380	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
D5125_12385	ENOG4108UM1	dedA family
D5125_12390	ENOG4108K5P	(LipO)protein
D5125_12395	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D5125_12400	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D5125_12405	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
D5125_12415	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
D5125_12430	ENOG4105IBP	Cyclic peptide transporter
D5125_12440	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
D5125_12445	ENOG4108IAB	Phoh family
D5125_12450	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D5125_12455	ENOG4105RH4	Glycine cleavage system transcriptional repressor
D5125_12460	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D5125_12465	ENOG4105GJM	(LipO)protein
D5125_12480	ENOG4108NVM	synthesis repressor PhaR
D5125_12485	ENOG4105CHU	acetyl-coa acetyltransferase
D5125_12490	ENOG4108U4D	synthase) subunit
D5125_12495	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
D5125_12500	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
D5125_12505	ENOG4108JU6	CBS domain protein
D5125_12510	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
D5125_12515	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D5125_12525	ENOG4105CRK	lysyL-tRNA synthetase
D5125_12530	ENOG4105DA4	cytochrome c-type biogenesis protein
D5125_12535	ENOG4107QX9	Thiol disulfide interChange protein
D5125_12540	ENOG4105KWW	Biogenesis protein
D5125_12545	ENOG4108M1T	Cytochrome c-type biogenesis protein
D5125_12555	ENOG4105CFV	Tetratricopeptide repeat protein
D5125_12560	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
D5125_12565	ENOG4107RIQ	Sulfate adenylate transferase
D5125_12580	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
D5125_12585	ENOG4105BZS	acriflavin resistance protein
D5125_12600	ENOG4108JA1	polyketide synthase
D5125_12605	ENOG4105CIP	K00612 carbamoyltransferase EC 2.1.3
D5125_12615	ENOG4105DUM	transcriptional regulator, lysR family
D5125_12620	ENOG4108R3D	Electron transport complex
D5125_12630	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
D5125_12635	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
D5125_12640	ENOG4105D6A	Electron transport complex
D5125_12645	ENOG41080WF	Electron transport complex, RnfABCDGE type, G subunit
D5125_12650	ENOG4105DZB	Electron transport complex
D5125_12655	ENOG4105DGN	Electron transport complex
D5125_12735	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
D5125_12755	ENOG41063ZP	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
D5125_12760	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
D5125_12770	ENOG4107EP5	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
D5125_12800	ENOG4105C9M	aspartyl-trna synthetase
D5125_12805	ENOG4105DH7	May be involved in recombination (By similarity)
D5125_12810	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
D5125_12830	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
D5125_12835	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D5125_12840	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D5125_12845	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D5125_12850	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D5125_12855	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D5125_12865	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
D5125_12870	ENOG4105BZU	Histidine kinase
D5125_12875	ENOG4105BZU	Histidine kinase
D5125_12880	ENOG4107YTP	response regulator receiver protein
D5125_12975	ENOG4105BZU	Histidine kinase
D5125_12980	ENOG4105BZU	Histidine kinase
D5125_12995	ENOG4108F3G	Type I restriction-modification system, R subunit
D5125_13025	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
D5125_13040	ENOG4107QTH	restriction modification system DNA specificity domain
D5125_13065	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
D5125_13070	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
D5125_13080	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
D5125_13085	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
D5125_13090	ENOG4105BZU	Histidine kinase
D5125_13095	ENOG4105BZU	Histidine kinase
D5125_13105	ENOG4105C8M	UPF0272 protein
D5125_13110	ENOG4105CHH	sulfate transporter
D5125_13125	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D5125_13150	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
D5125_13155	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
D5125_13160	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
D5125_13165	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D5125_13170	ENOG4105CGA	flagellar basal-body rod protein FlgG
D5125_13175	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D5125_13180	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
D5125_13185	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
D5125_13190	ENOG4105E1Q	flagellar hook-associated protein
D5125_13195	ENOG4105DTJ	flagellar hook-associated protein
D5125_13210	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
D5125_13215	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
D5125_13220	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D5125_13230	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D5125_13235	ENOG4105BZU	Histidine kinase
D5125_13245	ENOG4105UBK	short-chain dehydrogenase reductase
D5125_13250	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D5125_13255	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D5125_13260	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
D5125_13265	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
D5125_13270	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
D5125_13280	ENOG4105CHH	sulfate transporter
D5125_13290	ENOG41072GX	Peptidase M22 Glycoprotease
D5125_13305	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
D5125_13310	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
D5125_13315	ENOG41082RQ	UPF0102 protein
D5125_13320	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D5125_13325	ENOG4105W4M	Transport-associated protein
D5125_13330	ENOG4105CQB	FAD linked oxidase domain protein
D5125_13335	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D5125_13340	ENOG4105C9A	Phoh family
D5125_13345	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
D5125_13350	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
D5125_13370	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
D5125_13375	ENOG4105NBF	ammecr1 domain protein
D5125_13385	ENOG4105EXN	Sulfate transport protein CysZ
D5125_13390	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
D5125_13395	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D5125_13400	ENOG41082J7	Rhodanese domain protein
D5125_13405	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
D5125_13410	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
D5125_13435	ENOG4105CVG	Homoserine O-transsuccinylase
D5125_13470	ENOG4105BZU	Histidine kinase
D5125_13475	ENOG4105BZU	Histidine kinase
D5125_13480	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D5125_13500	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
D5125_13505	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
D5125_13510	ENOG4105N42	UPF0307 protein
D5125_13525	ENOG4105CEY	Amp-dependent synthetase and ligase
D5125_13540	ENOG4105F8J	Adenylate Guanylate cyclase
D5125_13555	ENOG4108RAC	Rubrerythrin
D5125_13585	ENOG41087AY	ADP-Ribose pyrophosphatase
D5125_13595	ENOG4107QTF	adenylosuccinate lyase
D5125_13600	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
D5125_13620	ENOG4105VC4	domain protein
D5125_13625	ENOG4105CSA	Coproporphyrinogen iii oxidase
D5125_13630	ENOG4108KXV	response regulator
D5125_13640	ENOG4105BZU	Histidine kinase
D5125_13650	ENOG4105BZU	Histidine kinase
D5125_13660	ENOG4105CFP	Peptidase U32
D5125_13665	ENOG4106RZ4	Peptidase U32
D5125_13670	ENOG4105XPQ	lipid carrier protein
D5125_13675	ENOG4105N5T	Radical SAM Protein
D5125_13690	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D5125_13695	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D5125_13700	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D5125_13755	ENOG4107QN1	sodium solute
D5125_13795	ENOG41067MG	lrgb family
D5125_13800	ENOG4105BZU	Histidine kinase
D5125_13810	ENOG4105ETE	Transcriptional regulator (LacI family
D5125_13815	ENOG4105BZU	Histidine kinase
D5125_13830	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
D5125_13835	ENOG4105W49	UPF0434 protein
D5125_13840	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
D5125_13845	ENOG4105EXS	phosphate abc transporter
D5125_13850	ENOG4105C8U	phosphate abc transporter
D5125_13860	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D5125_13865	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
D5125_13870	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
D5125_13880	ENOG4105D4P	Coproporphyrinogen iii oxidase
D5125_13890	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
D5125_13895	ENOG4108IYU	L-aspartate oxidase
D5125_13900	ENOG4105EMN	RNA polymerase sigma factor
D5125_13920	ENOG4105C0H	protease
D5125_13925	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
D5125_13930	ENOG4105C3F	Signal peptidase i
D5125_13940	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
D5125_13945	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
D5125_13950	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
D5125_13955	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
D5125_13965	ENOG4105BZU	Histidine kinase
D5125_13975	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
D5125_13980	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
D5125_13985	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
D5125_14020	ENOG4108M8S	permease YjgP YjgQ family protein
D5125_14025	ENOG4108K5H	permease YjgP YjgQ family protein
D5125_14035	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D5125_14045	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
D5125_14050	ENOG4105C34	Pseudouridine synthase
D5125_14055	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D5125_14065	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D5125_14080	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D5125_14095	ENOG4107RDB	Major Facilitator
D5125_14115	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
D5125_14120	ENOG4105BZU	Histidine kinase
D5125_14130	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D5125_14135	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
D5125_14140	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D5125_14145	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
D5125_14150	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
D5125_14160	ENOG4105VEQ	Cold shock protein
D5125_14165	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
D5125_14180	ENOG4105E96	Colicin v production protein
D5125_14185	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
D5125_14190	ENOG4105C28	cystathionine
D5125_14210	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
D5125_14220	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
D5125_14225	ENOG4108JU6	CBS domain protein
D5125_14230	ENOG4108JU6	CBS domain protein
D5125_14235	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
D5125_14240	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D5125_14245	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
D5125_14260	ENOG4105BZU	Histidine kinase
D5125_14285	ENOG4105DFS	Conserved Protein
D5125_14345	ENOG4105X0D	Fimbrial protein
D5125_14365	ENOG4105BZU	Histidine kinase
D5125_14370	ENOG4105CJR	Integral membrane protein (MviN
D5125_14380	ENOG4108V3W	Chemotaxis protein, CheW
D5125_14390	ENOG4105C1J	atp-dependent rna helicase
D5125_14405	ENOG4105CUW	cytochrome C-TYPE protein
D5125_14420	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
D5125_14425	ENOG4107QRG	dna polymerase iii
D5125_14435	ENOG4105F8V	Hydrolase, tatD family
D5125_14440	ENOG4105CSR	polyphosphate kinase 2
D5125_14445	ENOG4105C3M	thioredoxin reductase
D5125_14450	ENOG4105CNU	cell division protein FtsK
D5125_14455	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
D5125_14460	ENOG4105D1H	recombination factor protein RarA
D5125_14465	ENOG4105F8J	Adenylate Guanylate cyclase
D5125_14470	ENOG4108JJ7	ABC transporter
D5125_14475	ENOG4105MZU	cell filamentation protein
D5125_14480	ENOG4108KDI	dmso reductase anchor subunit
D5125_14535	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
D5125_14540	ENOG4105IFJ	Histidine kinase
D5125_14545	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
D5125_14555	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
D5125_14560	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D5125_14565	ENOG4108UHJ	MAF-like protein
D5125_14575	ENOG4105VGS	50s ribosomal protein l32
D5125_14580	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
D5125_14585	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D5125_14590	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D5125_14595	ENOG4105CHR	reductase
D5125_14600	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D5125_14605	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D5125_14610	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
D5125_14615	ENOG4105HHA	aminodeoxychorismate lyase
D5125_14635	ENOG4105BZU	Histidine kinase
D5125_14640	ENOG4105IJJ	transcriptional regulator, crp fnr family
D5125_14645	ENOG4105C0A	alcohol dehydrogenase
D5125_14725	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D5125_14955	ENOG4105BZ1	(ABC) transporter
D5125_15045	ENOG4108KQJ	Type 11 methyltransferase
D5125_15050	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
D5125_15075	ENOG4105VXP	Protein of unknown function DUF86
D5125_15115	ENOG4105X54	addiction module antidote protein
D5125_15140	ENOG4105JNK	Glycosyl transferase (Group 1
D5125_15145	ENOG4105C22	threonyL-tRNA synthetase
D5125_15150	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
D5125_15155	ENOG41082NX	50s ribosomal protein l35
D5125_15160	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
D5125_15165	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D5125_15170	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
D5125_15175	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D5125_15180	ENOG4105WJX	transcriptional regulator MERR family
D5125_15195	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D5125_15220	ENOG4105H2K	paraquat-inducible protein a
D5125_15225	ENOG4105F1S	paraquat-inducible protein a
D5125_15230	ENOG4105DY2	Paraquat-inducible protein b
D5125_15235	ENOG4105C0W	non-ribosomal peptide synthetase
D5125_15240	ENOG4105C0W	non-ribosomal peptide synthetase
D5125_15275	ENOG4107QTH	restriction modification system DNA specificity domain
D5125_15280	ENOG4107R3N	Filamentation induced by cAMP protein fic
D5125_15335	ENOG4105F5P	DNA-damage-inducible protein d
D5125_15375	ENOG4107RH8	nuclease SbcCD subunit D
D5125_15380	ENOG4105EYH	Exonuclease
D5125_15405	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
D5125_15415	ENOG4105C1G	acyl-Coa dehydrogenase
D5125_15425	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D5125_15460	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
D5125_15465	ENOG4105K8N	protein family UPF0079, ATPase
D5125_15470	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
D5125_15490	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
D5125_15495	ENOG4105NXV	High-affinity zinc uptake system protein
D5125_15505	ENOG4108R8Z	these effects are overcome by concomitant expression of antitoxin SohA (PrlF). Massive overexpression is toxic. Unlike most other characterized TA systems degrades rRNA, and co-folding of the proteins is necessary in vitro for inhibition of the RNase activity. It is not known if it has any sequence-specificity. Acts as a transcription factor. The YhaV PrlF complex binds the prlF-yhaV operon, probably negatively regulating its expression
D5125_15515	ENOG4105FAV	ABC, transporter
D5125_15530	ENOG4105BZS	acriflavin resistance protein
D5125_15535	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
D5125_15540	ENOG4105BZU	Histidine kinase
D5125_15550	ENOG4105DA5	(ABC) transporter
D5125_15555	ENOG4105E3A	(ABC) transporter
D5125_15565	ENOG4107QW3	Sucrose phosphorylase
D5125_15575	ENOG4106N16	had-superfamily hydrolase, subfamily iib
D5125_15595	ENOG4105CFU	surface antigen
D5125_15600	ENOG4105BZN	citrate synthase
D5125_15605	ENOG4105CR4	methylisocitrate lyase
D5125_15610	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D5125_15615	ENOG4105BZ1	(ABC) transporter
D5125_15625	ENOG4108RRZ	Transcription elongation factor GreB
D5125_15630	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D5125_15635	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
D5125_15640	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D5125_15650	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D5125_15655	ENOG4105C7F	AcnD-accessory protein PrpF
D5125_15660	ENOG4108I0Z	Aconitate hydratase
D5125_15665	ENOG4105C8Q	Methyl-accepting chemotaxis
D5125_15670	ENOG4105C5H	ABC transporter
D5125_15715	ENOG4105DSQ	Nitric oxide reductase
D5125_15720	ENOG4108VKQ	nitriC oxide reductase
D5125_15760	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
D5125_15770	ENOG4105C0D	helicase
D5125_15775	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D5125_15780	ENOG4105C0B	DNA polymerase III (alpha subunit)
D5125_15785	ENOG4105MPD	Cytochrome
D5125_15790	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
D5125_15795	ENOG4105CX6	glutaminyL-tRNA synthetase
D5125_15840	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
D5125_15845	ENOG4105GR3	Histidine kinase
D5125_15860	ENOG4105BZU	Histidine kinase
D5125_15870	ENOG4105BZU	Histidine kinase
D5125_15890	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
D5125_15900	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D5125_15915	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
D5125_15920	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D5125_15925	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D5125_15930	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D5125_15935	ENOG4105K70	DNA-binding protein
D5125_15950	ENOG4105EIN	peptidylprolyl cis-trans isomerase
D5125_15955	ENOG4105K4P	CoA-binding domain protein
D5125_15960	ENOG4107R0U	MotA TolQ exbB proton channel
D5125_15965	ENOG4106VK6	Flagellar motor protein
D5125_15970	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
D5125_15975	ENOG4105BZU	Histidine kinase
D5125_15985	ENOG4105VEJ	Heat shock protein
D5125_15990	ENOG4105VW4	glutaredoxin 3
D5125_15995	ENOG4105CD8	aminopeptidase N
D5125_16000	ENOG4105E14	MotA TolQ exbB proton channel
D5125_16005	ENOG4106VK6	Flagellar motor protein
D5125_16020	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
D5125_16025	ENOG4105CAT	Cytidine monophosphate kinase
D5125_16030	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D5125_16035	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
D5125_16045	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
D5125_16050	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
D5125_16060	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D5125_16070	ENOG4105C6T	cysteine synthase
D5125_16075	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D5125_16085	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
D5125_16095	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
D5125_16100	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
D5125_16105	ENOG4105D3R	alkyl hydroperoxide reductase
D5125_16110	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
D5125_16140	ENOG4105D0M	Protease HtpX homolog
D5125_16160	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
D5125_16220	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
D5125_16225	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
D5125_16230	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
D5125_16235	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
D5125_16240	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D5125_16245	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D5125_16250	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D5125_16255	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
D5125_16265	ENOG4107EJC	Preprotein translocase subunit SecG
D5125_16270	ENOG4105CP7	Triose-phosphate isomerase
D5125_16285	ENOG4105CQ7	ATP-dependent helicase
D5125_16290	ENOG4108IQK	o-acetylhomoserine
D5125_16295	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D5125_16315	ENOG4105ERG	peptidase m48, ste24p
D5125_16330	ENOG4105QN4	diheme cytochrome
D5125_16335	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
D5125_16340	ENOG4105BZU	Histidine kinase
D5125_16345	ENOG4108ZGN	Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC (By similarity)
D5125_16365	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
D5125_16370	ENOG4105C7S	Dehydrogenase
D5125_16380	ENOG41090R7	Ferric uptake
D5125_16385	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
D5125_16390	ENOG4105VN1	Heat shock protein
D5125_16400	ENOG4105E4C	Lytic transglycosylase catalytic
D5125_16405	ENOG4105K5B	UPF0225 protein
D5125_16425	ENOG41083J0	(ABC) transporter
D5125_16430	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D5125_16435	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
D5125_16445	ENOG4105C5X	domain protein
D5125_16465	ENOG4107TH8	cina domain protein
D5125_16480	ENOG4107835	probably involved in intracellular septation (By similarity)
D5125_16485	ENOG4105K9H	YciI-like protein
D5125_16490	ENOG4105EIN	peptidylprolyl cis-trans isomerase
D5125_16495	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
D5125_16510	ENOG4105CQ7	ATP-dependent helicase
D5125_16535	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
D5125_16540	ENOG4105T95	Thiol disulfide interChange protein
D5125_16545	ENOG4108VPT	UPF0234 protein
D5125_16550	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D5125_16555	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D5125_16560	ENOG4108ZZ3	UPF0260 protein
D5125_16570	ENOG4108ETH	Formylglycinamide ribotide synthetase
D5125_16580	ENOG4105CHR	reductase
D5125_16585	ENOG4105CD5	CoA-binding domain protein
D5125_16620	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
D5125_16625	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
D5125_16635	ENOG4108UJD	30S ribosomal protein S9
D5125_16640	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
D5125_16650	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
D5125_16660	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
D5125_16665	ENOG4108UKZ	OsmC family
D5125_16670	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
D5125_16685	ENOG4105TMB	Formate nitrite transporter
D5125_16695	ENOG4108IFG	nitrite reductase, (NAD(P)H)
D5125_16700	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
D5125_16710	ENOG4105VUH	addiction module killer protein
D5125_16715	ENOG4105DK0	Indole-3-glycerol phosphate synthase
D5125_16720	ENOG4105CP2	von willebrand factor, type a
D5125_16725	ENOG4108WQI	RNA Polymerase
D5125_16735	ENOG4108I0Q	anthranilate phosphoribosyltransferase
D5125_16740	ENOG41082AG	Plasmid maintenance system antidote protein
D5125_16745	ENOG4105DDQ	anthranilate synthase
D5125_16750	ENOG4105DGW	oligopeptidase A
D5125_16765	ENOG4105C25	Primosomal protein n'
D5125_16770	ENOG4105CDV	Ompa motb domain protein
D5125_16775	ENOG4105C75	arginyL-tRNA synthetase
D5125_16790	ENOG4105BZU	Histidine kinase
D5125_16795	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D5125_16805	ENOG4107QP8	phosphohexose isomerase
D5125_16815	ENOG4105FE9	pseudouridine synthase
D5125_16820	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
D5125_16825	ENOG4105D94	Major Facilitator Superfamily
D5125_16835	ENOG410696Y	Flagellar hook-length control protein
D5125_16840	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
D5125_16845	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D5125_16850	ENOG4105CFG	Acts as a chaperone (By similarity)
D5125_16855	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D5125_16860	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
D5125_16865	ENOG4108HU6	Metal dependent phosphohydrolase
D5125_16870	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D5125_16880	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
D5125_16885	ENOG4105CFH	Aspartokinase
D5125_16900	ENOG4105CFP	Peptidase U32
D5125_16915	ENOG4105D1F	ATP-binding protein
D5125_16920	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
D5125_16925	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D5125_16930	ENOG4105CKD	glutathione-regulated potassium-efflux system protein