locus-tag	class	description
Halar_0049	ENOG4105C0D	helicase
Halar_0055	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Halar_0061	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Halar_0106	ENOG4105C0D	helicase
Halar_0127	ENOG41065RQ	ADP-ribosylation crystallin J1
Halar_0130	ENOG41081QV	Universal stress protein
Halar_0141	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
Halar_0153	ENOG4105C0D	helicase
Halar_0167	ENOG4105F6J	Alpha beta hydrolase fold
Halar_0172	ENOG4105VZ8	Transcriptional regulator
Halar_0177	ENOG4105C4R	Atp-dependent dna helicase
Halar_0184	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Halar_0186	ENOG4105C1J	atp-dependent rna helicase
Halar_0234	ENOG4105C0D	helicase
Halar_0252	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Halar_0263	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
Halar_0299	ENOG4105BZU	Histidine kinase
Halar_0302	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
Halar_0305	ENOG4105CEY	Amp-dependent synthetase and ligase
Halar_0306	ENOG4105CHR	reductase
Halar_0308	ENOG4105ERH	Fumarylacetoacetate hydrolase
Halar_0311	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_0321	ENOG4108JQ7	(ABC) transporter
Halar_0322	ENOG4105C3U	ABC transporter
Halar_0324	ENOG4105CYC	Transferase
Halar_0327	ENOG41069M3	Transcriptional regulator
Halar_0348	ENOG4105BZU	Histidine kinase
Halar_0386	ENOG4105C0D	helicase
Halar_0386	ENOG4105C0D	helicase
Halar_0397	ENOG4108RAV	Conserved protein
Halar_0399	ENOG4108M4U	conserved membrane protein
Halar_0440	ENOG4107TAE	Glycosyl transferase (Group 1
Halar_0452	ENOG4105C59	p-type ATPase
Halar_0453	ENOG4105C59	p-type ATPase
Halar_0460	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Halar_0492	ENOG4105MRR	Transcriptional regulator (By similarity)
Halar_0496	ENOG4107QJE	Chromosome Partitioning Protein
Halar_0500	ENOG4105DVF	Cytosine-specific methyltransferase
Halar_0512	ENOG4105C0D	helicase
Halar_0535	ENOG4105BZU	Histidine kinase
Halar_0568	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Halar_0587	ENOG4105C59	p-type ATPase
Halar_0600	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Halar_0606	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Halar_0626	ENOG4105CKK	Glycosyl transferase, family 2
Halar_0631	ENOG4105CPK	Glycosyl transferase (Group 1
Halar_0658	ENOG4105D06	uba thif-type nad fad binding protein
Halar_0663	ENOG4107QJE	Chromosome Partitioning Protein
Halar_0701	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Halar_0720	ENOG4105C6K	Malic enzyme
Halar_0722	ENOG4105DEF	Extracellular solute-binding protein, family 5
Halar_0724	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_0725	ENOG4105C3U	ABC transporter
Halar_0727	ENOG41080XQ	Signal transduction protein with cbs domains
Halar_0735	ENOG4105DC7	peptidase M24
Halar_0739	ENOG4105C0H	protease
Halar_0740	ENOG4108S4H	thioesterase Superfamily protein
Halar_0745	ENOG4108S4C	acetyltransferase
Halar_0750	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Halar_0751	ENOG41061GT	Aldolase
Halar_0753	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Halar_0754	ENOG4107QX3	carboxylase
Halar_0758	ENOG4105D82	Glutamate dehydrogenase
Halar_0759	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Halar_0760	ENOG4105CHM	Aminotransferase
Halar_0763	ENOG4105CPC	Aldo Keto reductase
Halar_0767	ENOG4105C3M	thioredoxin reductase
Halar_0769	ENOG4105C8N	cysteinyl-tRNA synthetase
Halar_0774	ENOG4108535	NAD dependent epimerase/dehydratase family
Halar_0784	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Halar_0785	ENOG4105CEV	competence damage-inducible protein
Halar_0790	ENOG4105C11	sulfate adenylyltransferase), subunit 2
Halar_0793	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Halar_0794	ENOG4105F38	ABC transporter, permease
Halar_0795	ENOG4105D38	putrescine abc transporter
Halar_0803	ENOG41089UC	methyltransferase, type 11
Halar_0806	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Halar_0807	ENOG4107QTF	adenylosuccinate lyase
Halar_0811	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Halar_0813	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Halar_0814	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Halar_0821	ENOG4105EHG	Permease protein
Halar_0822	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Halar_0823	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Halar_0826	ENOG4108PNU	Involved in the degradation of specific anti-sigma factors (By similarity)
Halar_0838	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Halar_0840	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Halar_0850	ENOG4105H0N	Participates in electron transfer between P700 and the cytochrome b6-f complex in photosystem I
Halar_0852	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Halar_0853	ENOG4105DQU	oxidoreductase, subunit beta
Halar_0854	ENOG4107QI1	Mate efflux family protein
Halar_0856	ENOG4105CV8	reductase
Halar_0859	ENOG4105D07	Signal peptide peptidase, SppA
Halar_0869	ENOG4105CY0	Metallo-Beta-Lactamase
Halar_0871	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Halar_0876	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Halar_0878	ENOG4105F0N	pyrophosphate phospho-hydrolase
Halar_0886	ENOG4105DCG	PHP domain protein
Halar_0888	ENOG4105CTD	carboxy-peptidase
Halar_0895	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Halar_0902	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Halar_0904	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Halar_0911	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Halar_0917	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
Halar_0924	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Halar_0925	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Halar_0926	ENOG4105D6E	homoserine dehydrogenase
Halar_0928	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Halar_0931	ENOG4105D8V	Glucose sorbosone dehydrogenase
Halar_0935	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Halar_0938	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Halar_0939	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Halar_0940	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Halar_0941	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Halar_0943	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
Halar_0948	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Halar_0950	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Halar_0953	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Halar_0955	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Halar_0956	ENOG4107ZXU	DSBA oxidoreductase
Halar_0958	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Halar_0960	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Halar_0965	ENOG4105C9B	Cysteine desulfurase
Halar_0966	ENOG4108UNV	SUF system FeS assembly protein, NifU family
Halar_0971	ENOG4105EHU	Circadian clock protein KaiC
Halar_0973	ENOG4105JAB	phenazine biosynthesis protein, phzf family
Halar_0977	ENOG4106M32	3-dehydroquinate synthase
Halar_0983	ENOG4105CHR	reductase
Halar_0984	ENOG4105CHM	Aminotransferase
Halar_0985	ENOG4105CHF	Glutathione S-transferase
Halar_0987	ENOG4105DHP	deoxycytidine triphosphate deaminase
Halar_0992	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Halar_1001	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Halar_1003	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Halar_1010	ENOG4105CXK	mandelate racemase muconate lactonizing
Halar_1011	ENOG4105CXK	mandelate racemase muconate lactonizing
Halar_1017	ENOG4105ERH	Fumarylacetoacetate hydrolase
Halar_1018	ENOG4105D0M	Protease HtpX homolog
Halar_1028	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
Halar_1030	ENOG4105E39	Enoyl-CoA hydratase
Halar_1036	ENOG4105C26	Dehydrogenase
Halar_1038	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Halar_1039	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Halar_1040	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Halar_1051	ENOG4105C26	Dehydrogenase
Halar_1062	ENOG4107QN2	dihydrolipoyl dehydrogenase
Halar_1066	ENOG4105DWF	phosphomethylpyrimidine kinase
Halar_1067	ENOG4105ETU	transcriptional activator (TenA
Halar_1069	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Halar_1072	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
Halar_1074	ENOG4105HMI	Membrane
Halar_1075	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
Halar_1078	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Halar_1086	ENOG4105ERH	Fumarylacetoacetate hydrolase
Halar_1088	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
Halar_1103	ENOG4107HP6	Transcriptional regulator
Halar_1106	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
Halar_1117	ENOG4108IGT	Dipeptidase
Halar_1118	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Halar_1120	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Halar_1123	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_1131	ENOG4105CK7	Sodium proline symporter
Halar_1134	ENOG4105D7N	magnesium and cobalt transport protein CorA
Halar_1137	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
Halar_1142	ENOG4108JQ7	(ABC) transporter
Halar_1143	ENOG4105C3U	ABC transporter
Halar_1144	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_1146	ENOG4108J59	Extracellular solute-binding protein, family 5
Halar_1155	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Halar_1157	ENOG4108RMU	ferritin dps family protein
Halar_1160	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Halar_1169	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Halar_1172	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Halar_1173	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Halar_1176	ENOG4105KVH	Transcriptional regulator
Halar_1177	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Halar_1179	ENOG41068T5	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT (By similarity)
Halar_1181	ENOG4105DV0	amidase (EC 3.5.1.4
Halar_1182	ENOG4105RAK	Histidine kinase
Halar_1185	ENOG4105EAC	phosphoserine phosphatase
Halar_1199	ENOG4105CDH	Citrulline--aspartate ligase
Halar_1200	ENOG4105CH7	arginosuccinase
Halar_1202	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Halar_1203	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Halar_1204	ENOG4107U4Q	acetylglutamate kinase
Halar_1205	ENOG4105C8Y	Acetylornithine aminotransferase
Halar_1206	ENOG4107SBK	Acetylornithine deacetylase
Halar_1207	ENOG4105DBV	ornithine carbamoyltransferase
Halar_1209	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Halar_1210	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Halar_1212	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
Halar_1213	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
Halar_1218	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Halar_1220	ENOG4107QJE	Chromosome Partitioning Protein
Halar_1222	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Halar_1224	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Halar_1226	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Halar_1227	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Halar_1241	ENOG4105QAX	Iron-sulfur
Halar_1242	ENOG4108IEG	Formate dehydrogenase Alpha subunit
Halar_1244	ENOG4109039	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
Halar_1250	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Halar_1253	ENOG4108IJ8	ABC transporter
Halar_1259	ENOG4105JZI	cytochrome P450
Halar_1262	ENOG4105KAV	tspo and mbr like protein
Halar_1264	ENOG4105CV8	reductase
Halar_1265	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Halar_1266	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Halar_1268	ENOG4105C1G	acyl-Coa dehydrogenase
Halar_1274	ENOG4105C7K	acetolactate synthase
Halar_1275	ENOG4105VFE	sira family
Halar_1277	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Halar_1283	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_1284	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Halar_1288	ENOG4105C1A	potassium transporter peripheral membrane
Halar_1289	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Halar_1294	ENOG4105C12	Phosphoribosylglycinamide synthetase
Halar_1303	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Halar_1306	ENOG4105EYH	Exonuclease
Halar_1315	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Halar_1316	ENOG4105DDQ	anthranilate synthase
Halar_1317	ENOG4105CRQ	synthase (Component I)
Halar_1319	ENOG4105E2X	shikimate dehydrogenase
Halar_1322	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Halar_1326	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Halar_1328	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
Halar_1329	ENOG4105CJW	magnesium transporter
Halar_1338	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Halar_1340	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Halar_1341	ENOG4105C8S	subunit m
Halar_1347	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Halar_1348	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Halar_1349	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Halar_1350	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Halar_1353	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Halar_1354	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Halar_1360	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
Halar_1361	ENOG4105CXT	aspartate transcarbamylase
Halar_1362	ENOG4105C98	muts2 protein
Halar_1366	ENOG4105KFG	YeeE YedE family protein
Halar_1369	ENOG4105C1G	acyl-Coa dehydrogenase
Halar_1370	ENOG4105CEY	Amp-dependent synthetase and ligase
Halar_1380	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Halar_1384	ENOG4105E39	Enoyl-CoA hydratase
Halar_1386	ENOG4105EW6	flavin reductase domain protein, FMN-binding
Halar_1392	ENOG4107TH8	cina domain protein
Halar_1393	ENOG4107UA9	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) (By similarity)
Halar_1395	ENOG4108EHY	type IV secretion system
Halar_1403	ENOG4107TE5	Lipid kinase
Halar_1416	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Halar_1419	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Halar_1420	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Halar_1422	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Halar_1424	ENOG4105C7K	acetolactate synthase
Halar_1426	ENOG4105C01	Dihydroxy-acid dehydratase
Halar_1429	ENOG4105MRR	Transcriptional regulator (By similarity)
Halar_1435	ENOG4108JQ7	(ABC) transporter
Halar_1437	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_1441	ENOG4105E8R	UPF0173 metal-dependent hydrolase
Halar_1449	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Halar_1450	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
Halar_1451	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Halar_1452	ENOG4105ECY	inositol monophosphatase
Halar_1459	ENOG410667J	hydrolase
Halar_1461	ENOG4105FE1	phytoene synthase
Halar_1462	ENOG4105C1G	acyl-Coa dehydrogenase
Halar_1467	ENOG4105E2K	Glycosyl transferase (Group 1
Halar_1472	ENOG4105C1G	acyl-Coa dehydrogenase
Halar_1477	ENOG4105DDR	sarcosine oxidase (Beta subunit)
Halar_1479	ENOG4105F44	Two component transcriptional regulator, winged helix family
Halar_1480	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Halar_1483	ENOG4105D1Z	hydroxypyruvate reductase
Halar_1488	ENOG41080XP	Cbs domain
Halar_1494	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Halar_1499	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Halar_1501	ENOG4105E4F	Isochorismate synthase
Halar_1502	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
Halar_1505	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
Halar_1506	ENOG4107WEA	mandelate racemase muconate lactonizing
Halar_1507	ENOG4105CGU	Enoyl-CoA hydratase
Halar_1508	ENOG4105DFD	Na H antiporter
Halar_1510	ENOG4105DWV	Homoserine O-trans-acetylase
Halar_1512	ENOG4105UQX	Mate efflux family protein
Halar_1518	ENOG4105C1Q	protoporphyrinogen oxidase
Halar_1533	ENOG4108T0W	nitrous oxide maturation protein NosY
Halar_1537	ENOG4108TQ9	Histidine kinase
Halar_1545	ENOG4107104	thymidine kinase
Halar_1547	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Halar_1549	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Halar_1552	ENOG4108UJD	30S ribosomal protein S9
Halar_1556	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Halar_1558	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Halar_1559	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
Halar_1562	ENOG4105D1F	ATP-binding protein
Halar_1568	ENOG4105DBI	uridine monophosphokinase
Halar_1572	ENOG4105CHM	Aminotransferase
Halar_1574	ENOG4105DG7	nitrate ABC transporter
Halar_1581	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Halar_1593	ENOG4105D0M	Protease HtpX homolog
Halar_1594	ENOG4105C37	(CBS) domain
Halar_1607	ENOG4105CBG	Sulfatase
Halar_1611	ENOG4107QPH	glycogen) synthase
Halar_1612	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Halar_1613	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
Halar_1615	ENOG4105CMR	udp-glucose 4-epimerase
Halar_1616	ENOG4105CMR	udp-glucose 4-epimerase
Halar_1617	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Halar_1624	ENOG4105CQB	FAD linked oxidase domain protein
Halar_1625	ENOG4105C5R	Aminotransferase
Halar_1631	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Halar_1632	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Halar_1634	ENOG4105DYW	oxidoreductase
Halar_1636	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
Halar_1640	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Halar_1642	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Halar_1643	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
Halar_1646	ENOG4108IEG	Formate dehydrogenase Alpha subunit
Halar_1663	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Halar_1667	ENOG4105C3G	gtp-binding protein
Halar_1673	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Halar_1676	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Halar_1677	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_1679	ENOG4108JQ7	(ABC) transporter
Halar_1691	ENOG4105KPK	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (By similarity)
Halar_1693	ENOG4107T0X	DNA ligase
Halar_1694	ENOG4105E8R	UPF0173 metal-dependent hydrolase
Halar_1696	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Halar_1704	ENOG4105C3G	gtp-binding protein
Halar_1707	ENOG4107QHQ	amino acid
Halar_1712	ENOG4108JPW	Aminotransferase
Halar_1720	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Halar_1721	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Halar_1726	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Halar_1727	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Halar_1733	ENOG4105C8Y	Acetylornithine aminotransferase
Halar_1735	ENOG4105ENR	peptidase, M24
Halar_1744	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Halar_1745	ENOG4105D81	ABC transporter, permease
Halar_1746	ENOG4105D38	putrescine abc transporter
Halar_1748	ENOG4108DN8	FAD dependent oxidoreductase
Halar_1749	ENOG4107W9I	Creatinine amidohydrolase
Halar_1750	ENOG4105C5I	Dehydrogenase
Halar_1751	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Halar_1752	ENOG4108IV0	ABC, transporter
Halar_1753	ENOG4105C0Z	ABC transporter
Halar_1755	ENOG4105C32	Amino acid ABC transporter (Permease)
Halar_1758	ENOG41066FR	extracellular solute-binding protein
Halar_1760	ENOG4108IJ6	ABC transporter
Halar_1768	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
Halar_1769	ENOG4105DCI	Phosphohydrolase
Halar_1771	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
Halar_1772	ENOG4105DYW	oxidoreductase
Halar_1782	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Halar_1783	ENOG4108NGU	Transcriptional regulator
Halar_1785	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Halar_1788	ENOG4105VEQ	Cold shock protein
Halar_1793	ENOG4108Q27	Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate (By similarity)
Halar_1794	ENOG4108IJ9	(ABC) transporter
Halar_1795	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
Halar_1796	ENOG4105F0P	binding-protein-dependent transport systems inner membrane Component
Halar_1798	ENOG4105C19	ABC transporter
Halar_1799	ENOG4107RBB	ABC transporter, permease
Halar_1805	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Halar_1807	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
Halar_1808	ENOG4108JQ1	Dehydrogenase
Halar_1810	ENOG4105CPC	Aldo Keto reductase
Halar_1813	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Halar_1820	ENOG4105C1Q	protoporphyrinogen oxidase
Halar_1823	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Halar_1825	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Halar_1829	ENOG4105C28	cystathionine
Halar_1833	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Halar_1834	ENOG4105D8X	mechanosensitive ion channel
Halar_1838	ENOG4105CN9	Peptidase m42 family protein
Halar_1839	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
Halar_1846	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Halar_1856	ENOG4108VVK	transcriptional Regulator, AsnC
Halar_1857	ENOG4105ECY	inositol monophosphatase
Halar_1860	ENOG4105BZU	Histidine kinase
Halar_1862	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Halar_1864	ENOG4105C8M	UPF0272 protein
Halar_1865	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Halar_1866	ENOG4107S5I	aldo keto reductase
Halar_1869	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Halar_1870	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Halar_1871	ENOG4105C8U	phosphate abc transporter
Halar_1872	ENOG4105C8U	phosphate abc transporter
Halar_1873	ENOG4105PWN	phosphate abc transporter
Halar_1874	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Halar_1880	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Halar_1882	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Halar_1883	ENOG41080TK	Universal stress protein
Halar_1884	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Halar_1885	ENOG4105D8K	carboxyl transferase
Halar_1893	ENOG4105DCI	Phosphohydrolase
Halar_1898	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Halar_1907	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
Halar_1908	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Halar_1915	ENOG4107S4Y	M20 DapE family protein YgeY
Halar_1926	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
Halar_1930	ENOG4105CD3	dihydroorotase
Halar_1942	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Halar_1948	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Halar_1957	ENOG4105CPF	Cell wall formation (By similarity)
Halar_1960	ENOG4105CPC	Aldo Keto reductase
Halar_1961	ENOG4105CH2	amidohydrolase
Halar_1965	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Halar_1972	ENOG4105DTQ	mandelate racemase muconate lactonizing
Halar_2012	ENOG4108JQ7	(ABC) transporter
Halar_2014	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_2017	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Halar_2020	ENOG4108JQ7	(ABC) transporter
Halar_2021	ENOG4105C3U	ABC transporter
Halar_2022	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_2024	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
Halar_2025	ENOG4105DC7	peptidase M24
Halar_2028	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
Halar_2040	ENOG4105CI2	imidazolone-5-propionate hydrolase
Halar_2043	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Halar_2045	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Halar_2048	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Halar_2052	ENOG4107RSR	Malate quinone oxidoreductase
Halar_2076	ENOG4105E0R	Deoxyhypusine synthase
Halar_2078	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
Halar_2079	ENOG4105CYW	agmatinase
Halar_2081	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Halar_2082	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Halar_2084	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Halar_2088	ENOG4108WBT	adenosyltransferase
Halar_2091	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Halar_2092	ENOG4105C1G	acyl-Coa dehydrogenase
Halar_2096	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
Halar_2101	ENOG4105CJ1	ABC, transporter
Halar_2103	ENOG4105CX6	glutaminyL-tRNA synthetase
Halar_2104	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Halar_2115	ENOG4105EWK	phytoene
Halar_2119	ENOG4105D7V	transposase
Halar_2123	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Halar_2130	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Halar_2138	ENOG4105C32	Amino acid ABC transporter (Permease)
Halar_2139	ENOG4105C0Z	ABC transporter
Halar_2140	ENOG4108IV0	ABC, transporter
Halar_2141	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Halar_2143	ENOG4105CQB	FAD linked oxidase domain protein
Halar_2150	ENOG4105CV8	reductase
Halar_2154	ENOG4107PP3	Acetylornithine deacetylase
Halar_2155	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
Halar_2158	ENOG4105C26	Dehydrogenase
Halar_2160	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Halar_2161	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_2163	ENOG4108JQ7	(ABC) transporter
Halar_2164	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Halar_2166	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Halar_2167	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Halar_2170	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Halar_2174	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
Halar_2175	ENOG4105C58	cytochrome c oxidase accessory protein ccog
Halar_2178	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Halar_2183	ENOG4105CGH	5'-nucleotidase
Halar_2189	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Halar_2191	ENOG4105WMR	Protein CrcB homolog
Halar_2192	ENOG4105CN9	Peptidase m42 family protein
Halar_2195	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Halar_2199	ENOG4108AQF	aminoglycoside N(3)-acetyltransferase
Halar_2204	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Halar_2211	ENOG4105D3Q	Sugar transferase
Halar_2212	ENOG4105D7V	transposase
Halar_2213	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
Halar_2221	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Halar_2224	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Halar_2226	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Halar_2228	ENOG4105D64	Mechanosensitive ion channel
Halar_2229	ENOG4105CHM	Aminotransferase
Halar_2231	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Halar_2232	ENOG4105CQB	FAD linked oxidase domain protein
Halar_2233	ENOG4105C8V	SAICAR synthetase
Halar_2235	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Halar_2242	ENOG4105CV8	reductase
Halar_2248	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Halar_2249	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Halar_2252	ENOG4105M00	molybdopterin converting factor, subunit 1
Halar_2255	ENOG4107SVH	Potassium channel protein
Halar_2257	ENOG4107SXA	Phosphorylase
Halar_2260	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Halar_2274	ENOG4108J5G	6-phosphogluconate dehydrogenase
Halar_2277	ENOG4105CIG	ABC transporter
Halar_2279	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Halar_2289	ENOG4108RAV	Conserved protein
Halar_2290	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
Halar_2293	ENOG4105BZU	Histidine kinase
Halar_2298	ENOG4107Y9E	nuclease
Halar_2302	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_2303	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Halar_2308	ENOG4105K4P	CoA-binding domain protein
Halar_2311	ENOG4107S4Y	M20 DapE family protein YgeY
Halar_2315	ENOG4105ERH	Fumarylacetoacetate hydrolase
Halar_2316	ENOG4105DC7	peptidase M24
Halar_2319	ENOG4107RUE	extracellular solute-binding protein family 1
Halar_2320	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Halar_2322	ENOG4105D38	putrescine abc transporter
Halar_2323	ENOG4105CP9	extracellular ligand-binding receptor
Halar_2324	ENOG4105C32	Amino acid ABC transporter (Permease)
Halar_2326	ENOG4105C0Z	ABC transporter
Halar_2327	ENOG4108IV0	ABC, transporter
Halar_2330	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Halar_2331	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Halar_2333	ENOG4108JQ9	ABC transporter
Halar_2334	ENOG4105UIB	(ABC) transporter
Halar_2337	ENOG4105CH2	amidohydrolase
Halar_2339	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Halar_2342	ENOG4105C3M	thioredoxin reductase
Halar_2344	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Halar_2351	ENOG4108EHY	type IV secretion system
Halar_2358	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Halar_2359	ENOG4108RVA	ribokinase
Halar_2371	ENOG4105C26	Dehydrogenase
Halar_2375	ENOG4105DZS	Phenylacetate-CoA ligase
Halar_2377	ENOG4108RTE	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales (By similarity)
Halar_2382	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Halar_2384	ENOG4105ES5	Histidine kinase
Halar_2385	ENOG4105BZ1	(ABC) transporter
Halar_2393	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Halar_2394	ENOG4105KJM	monovalent cation h antiporter subunit g
Halar_2396	ENOG4105SC1	monovalent cation H antiporter subunit E
Halar_2397	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Halar_2399	ENOG4105GND	monovalent cation H antiporter subunit B
Halar_2400	ENOG4105D65	subunit l
Halar_2401	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Halar_2409	ENOG4105C9B	Cysteine desulfurase
Halar_2428	ENOG4105CUB	amino acid
Halar_2433	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Halar_2449	ENOG4107STQ	Multicopper oxidase
Halar_2452	ENOG4105D82	Glutamate dehydrogenase
Halar_2455	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Halar_2459	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Halar_2464	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Halar_2465	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Halar_2466	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Halar_2468	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Halar_2471	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Halar_2472	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Halar_2474	ENOG41082SA	50s ribosomal protein l29
Halar_2475	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Halar_2477	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Halar_2478	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Halar_2481	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Halar_2487	ENOG4105CTD	carboxy-peptidase
Halar_2488	ENOG4105FBW	Monooxygenase
Halar_2489	ENOG4105CHR	reductase
Halar_2492	ENOG4105CVJ	phosphoglycerate mutase
Halar_2495	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
Halar_2499	ENOG4105C32	Amino acid ABC transporter (Permease)
Halar_2501	ENOG4105C0Z	ABC transporter
Halar_2502	ENOG4108IV0	ABC, transporter
Halar_2504	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
Halar_2506	ENOG4105D8X	mechanosensitive ion channel
Halar_2508	ENOG4107K5X	Membrane-bound metal-dependent hydrolase
Halar_2515	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Halar_2526	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Halar_2543	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Halar_2545	ENOG4105D2T	synthase
Halar_2551	ENOG4105F0R	Cytidylyltransferase
Halar_2553	ENOG4107EF8	Glycosyl transferase (Group 1
Halar_2556	ENOG4105BZ1	(ABC) transporter
Halar_2561	ENOG4105CEY	Amp-dependent synthetase and ligase
Halar_2564	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Halar_2569	ENOG4107YZX	Universal stress protein
Halar_2571	ENOG4107TPS	domain protein
Halar_2573	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Halar_2577	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Halar_2578	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Halar_2581	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Halar_2591	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
Halar_2592	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
Halar_2601	ENOG4105FCD	Major Facilitator
Halar_2608	ENOG4105C9Q	fumarate hydratase class II
Halar_2610	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Halar_2612	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Halar_2613	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Halar_2616	ENOG4105DXM	phenylacetic acid degradation protein
Halar_2625	ENOG4105CQB	FAD linked oxidase domain protein
Halar_2626	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Halar_2627	ENOG4108I5C	dEAD DEAH box helicase
Halar_2628	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Halar_2629	ENOG4105CFG	Acts as a chaperone (By similarity)
Halar_2630	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Halar_2632	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Halar_2634	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Halar_2639	ENOG4107SXA	Phosphorylase
Halar_2643	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
Halar_2645	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Halar_2646	ENOG4105C7B	Threonine dehydratase
Halar_2647	ENOG4108JQ7	(ABC) transporter
Halar_2649	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_2651	ENOG4108J59	Extracellular solute-binding protein, family 5
Halar_2653	ENOG4105D7K	pfkb domain protein
Halar_2680	ENOG4105E0F	Histidine kinase
Halar_2683	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Halar_2684	ENOG4105DPN	Oligoendopeptidase f
Halar_2687	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Halar_2689	ENOG4105CUT	histidyl-tRNA synthetase
Halar_2693	ENOG4105FF5	Membrane
Halar_2694	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Halar_2697	ENOG4108ZAF	Molybdopterin
Halar_2698	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Halar_2699	ENOG4105DK7	lysyl-tRNA synthetase
Halar_2702	ENOG4107JTW	chlorite dismutase
Halar_2710	ENOG4105C4K	Nad synthetase
Halar_2714	ENOG41082W1	Cupin 2, conserved barrel domain protein
Halar_2720	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Halar_2722	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Halar_2727	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Halar_2729	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Halar_2732	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Halar_2738	ENOG4105CHU	acetyl-coa acetyltransferase
Halar_2739	ENOG4105C5X	domain protein
Halar_2741	ENOG4108IQE	Amp-dependent synthetase and ligase
Halar_2744	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Halar_2747	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Halar_2749	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Halar_2750	ENOG4105MPN	Membrane
Halar_2752	ENOG4105NCW	Trka-c domain protein
Halar_2753	ENOG4107S91	Sodium hydrogen exchanger
Halar_2757	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Halar_2758	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Halar_2763	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Halar_2771	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Halar_2775	ENOG4105C89	phosphohexose isomerase
Halar_2782	ENOG4105FBW	Monooxygenase
Halar_2783	ENOG4108UZX	fmn reductase
Halar_2790	ENOG4105E0X	reductase
Halar_2794	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Halar_2796	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
Halar_2797	ENOG4108TQ9	Histidine kinase
Halar_2799	ENOG4105CPQ	Dehydrogenase
Halar_2800	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
Halar_2810	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Halar_2811	ENOG4108Z4J	Cytidine monophosphate kinase
Halar_2812	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Halar_2813	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Halar_2814	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Halar_2818	ENOG4105KZX	Pterin carbinolamine dehydratase
Halar_2819	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Halar_2824	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Halar_2828	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Halar_2830	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
Halar_2832	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
Halar_2838	ENOG4105E9Z	Nad-dependent epimerase dehydratase
Halar_2845	ENOG4107YBY	Hydrolase
Halar_2847	ENOG4105UQX	Mate efflux family protein
Halar_2848	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Halar_2850	ENOG4105CPP	Dehydrogenase, E1 component
Halar_2851	ENOG4105C7S	Dehydrogenase
Halar_2853	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
Halar_2854	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Halar_2856	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Halar_2864	ENOG410811Q	Ferredoxin
Halar_2865	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Halar_2868	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Halar_2872	ENOG4108HMX	isocitrate dehydrogenase (NADP)
Halar_2873	ENOG4105D44	asparaginase
Halar_2877	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Halar_2882	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Halar_2886	ENOG4105C75	arginyL-tRNA synthetase
Halar_2888	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Halar_2889	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Halar_2891	ENOG4105C32	Amino acid ABC transporter (Permease)
Halar_2892	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Halar_2893	ENOG4105C0Z	ABC transporter
Halar_2894	ENOG4108IV0	ABC, transporter
Halar_2896	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
Halar_2897	ENOG4105D06	uba thif-type nad fad binding protein
Halar_2899	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Halar_2900	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Halar_2902	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Halar_2904	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Halar_2916	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Halar_2917	ENOG410811Q	Ferredoxin
Halar_2918	ENOG4105UQX	Mate efflux family protein
Halar_2924	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Halar_2932	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Halar_2935	ENOG4105KHC	sulfurtransferase
Halar_2945	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Halar_2949	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Halar_2957	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Halar_2958	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Halar_2962	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Halar_2968	ENOG4106178	UPF0339 protein
Halar_2969	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Halar_2970	ENOG4107QRG	dna polymerase iii
Halar_2972	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Halar_2991	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Halar_2995	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Halar_3000	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Halar_3004	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Halar_3005	ENOG4108UZX	fmn reductase
Halar_3006	ENOG4105VC4	domain protein
Halar_3009	ENOG4105E66	phosphoriboisomerase A
Halar_3010	ENOG4105N14	lysine exporter protein LysE YggA
Halar_3018	ENOG4105EAH	synthase
Halar_3019	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Halar_3026	ENOG4105EBX	v-type atpase
Halar_3031	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
Halar_3032	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
Halar_3033	ENOG4108570	YjeF-related protein N-terminus
Halar_3035	ENOG4107W9I	Creatinine amidohydrolase
Halar_3037	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Halar_3044	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Halar_3047	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Halar_3058	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Halar_3059	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Halar_3065	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
Halar_3070	ENOG4105E9S	glutaredoxin 2
Halar_3072	ENOG4105C7N	Xanthine uracil vitamin C permease
Halar_3073	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Halar_3074	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Halar_3087	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Halar_3088	ENOG4105DMT	epimerase dehydratase
Halar_3091	ENOG4105DY8	decarboxylase
Halar_3098	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Halar_3102	ENOG4105CUB	amino acid
Halar_3110	ENOG4105D6J	arsenicaL-resistance protein
Halar_3112	ENOG4105CA9	Pyruvate kinase
Halar_3113	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
Halar_3116	ENOG4105C26	Dehydrogenase
Halar_3117	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Halar_3118	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Halar_3119	ENOG4107RUE	extracellular solute-binding protein family 1
Halar_3120	ENOG4105D38	putrescine abc transporter
Halar_3121	ENOG4105F38	ABC transporter, permease
Halar_3122	ENOG4105EW9	transcriptional regulator AsnC family
Halar_3125	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Halar_3126	ENOG41080HI	glycine oxidase
Halar_3146	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Halar_3147	ENOG4108IGT	Dipeptidase
Halar_3150	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Halar_3160	ENOG4105E0F	Histidine kinase
Halar_3168	ENOG41061GT	Aldolase
Halar_3169	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Halar_3170	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Halar_3171	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Halar_3175	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Halar_3190	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
Halar_3192	ENOG4105C7B	Threonine dehydratase
Halar_3193	ENOG4105KME	endoribonuclease L-psp
Halar_3201	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
Halar_3203	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Halar_3209	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Halar_3213	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Halar_3215	ENOG4105C28	cystathionine
Halar_3221	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Halar_3227	ENOG4105C5S	asparaginyl-tRNA synthetase
Halar_3228	ENOG4105C37	(CBS) domain
Halar_3230	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Halar_3231	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Halar_3234	ENOG4107ZYJ	bioY protein
Halar_3235	ENOG4108JJB	ABC transporter
Halar_3236	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
Halar_3238	ENOG4105DF6	Fe-S oxidoreductase
Halar_3245	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Halar_3248	ENOG4105K64	Glycosyl transferase, family 2
Halar_3254	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Halar_3255	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Halar_3256	ENOG4105C1G	acyl-Coa dehydrogenase
Halar_3265	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Halar_3267	ENOG4105FF2	Type I DHQase
Halar_3269	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Halar_3278	ENOG4107RCV	ABC transporter, permease
Halar_3279	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Halar_3282	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
Halar_3284	ENOG4105CB5	ATP-dependent DNA helicase recG
Halar_3289	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Halar_3290	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Halar_3292	ENOG4105CFH	Aspartokinase
Halar_3295	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Halar_3296	ENOG4105BZN	citrate synthase
Halar_3302	ENOG4107QR9	Iron-sulfur cluster binding protein
Halar_3303	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Halar_3305	ENOG4105K63	Thioredoxin
Halar_3308	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Halar_3309	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Halar_3322	ENOG4108JPW	Aminotransferase
Halar_3327	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Halar_3329	ENOG4105DTQ	mandelate racemase muconate lactonizing
Halar_3338	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_3339	ENOG4105C3U	ABC transporter
Halar_3340	ENOG4108JQ7	(ABC) transporter
Halar_3346	ENOG4105C7B	Threonine dehydratase
Halar_3347	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
Halar_3349	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
Halar_3351	ENOG4108IGT	Dipeptidase
Halar_3369	ENOG4105D52	delta-aminolevulinic acid dehydratase
Halar_3370	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Halar_3371	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Halar_3374	ENOG4107ZT3	family UPF0126
Halar_3376	ENOG4108IUQ	atp-dependent protease
Halar_3378	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Halar_3379	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Halar_3382	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Halar_3386	ENOG4105Q9Y	Universal stress protein
Halar_3391	ENOG4107SET	aldo keto reductase
Halar_3394	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Halar_3400	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Halar_3401	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Halar_3403	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
Halar_3405	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Halar_3407	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Halar_3409	ENOG4105C8Y	Acetylornithine aminotransferase
Halar_3413	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Halar_3414	ENOG4105D38	putrescine abc transporter
Halar_3415	ENOG4105F38	ABC transporter, permease
Halar_3416	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Halar_3418	ENOG4108HMX	isocitrate dehydrogenase (NADP)
Halar_3424	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
Halar_3426	ENOG4108IV0	ABC, transporter
Halar_3427	ENOG4105C0Z	ABC transporter
Halar_3429	ENOG4105C32	Amino acid ABC transporter (Permease)
Halar_3436	ENOG4105DEF	Extracellular solute-binding protein, family 5
Halar_3437	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
Halar_3438	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_3439	ENOG4108JQ6	ABC transporter
Halar_3440	ENOG4105CI0	Citrate lyase
Halar_3441	ENOG4105CD5	CoA-binding domain protein
Halar_3447	ENOG4105D1F	ATP-binding protein
Halar_3464	ENOG4105VEQ	Cold shock protein
Halar_3481	ENOG4105E9Z	Nad-dependent epimerase dehydratase
Halar_3485	ENOG4105BZ1	(ABC) transporter
Halar_3491	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
Halar_3492	ENOG4105VFE	sira family
Halar_3493	ENOG4107TPS	domain protein
Halar_3495	ENOG4105KFG	YeeE YedE family protein
Halar_3513	ENOG4105C0B	DNA polymerase III (alpha subunit)
Halar_3514	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
Halar_3516	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Halar_3517	ENOG4107QRT	dEAD DEAH box helicase
Halar_3521	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Halar_3527	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Halar_3528	ENOG4105DQU	oxidoreductase, subunit beta
Halar_3529	ENOG4108XM1	transcriptional regulator AsnC family
Halar_3530	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Halar_3535	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Halar_3537	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Halar_3539	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Halar_3542	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
Halar_3543	ENOG4105C37	(CBS) domain
Halar_3544	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
Halar_3546	ENOG4105C6T	cysteine synthase
Halar_3548	ENOG4105C7Z	Conserved Protein
Halar_3550	ENOG4105C12	Phosphoribosylglycinamide synthetase
Halar_3553	ENOG4105E39	Enoyl-CoA hydratase
Halar_3554	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Halar_3555	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Halar_3556	ENOG4105CHU	acetyl-coa acetyltransferase
Halar_3573	ENOG4107TPS	domain protein
Halar_3581	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
Halar_3584	ENOG4105VG1	fes assembly suf system protein
Halar_3590	ENOG4105C3K	feS assembly ATPase SufC
Halar_3591	ENOG4105DIW	FeS assembly protein SUFB
Halar_3592	ENOG4105DIW	FeS assembly protein SUFB
Halar_3612	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Halar_3614	ENOG4108DMA	Nad-dependent epimerase dehydratase
Halar_3615	ENOG4107R5I	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
Halar_3616	ENOG4105CHU	acetyl-coa acetyltransferase
Halar_3618	ENOG4105CPT	Alpha beta hydrolase
Halar_3629	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Halar_3630	ENOG4108R6B	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
Halar_3641	ENOG4105EWK	phytoene
Halar_3644	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Halar_3651	ENOG4105D5P	Methylmalonyl-coA mutase
Halar_3652	ENOG4105DJT	lAO AO transport system ATPase
Halar_3654	ENOG4105CEV	competence damage-inducible protein
Halar_3659	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Halar_3662	ENOG4105HDK	L-asparaginase
Halar_3670	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Halar_3675	ENOG4105E1F	short-chain dehydrogenase reductase
Halar_3676	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
Halar_3685	ENOG4105CHM	Aminotransferase
Halar_3688	ENOG4105ENA	helicase
Halar_3689	ENOG4105DC7	peptidase M24
Halar_3691	ENOG4108R6K	riboflavin synthase, subunit alpha
Halar_3694	ENOG4108IJ9	(ABC) transporter
Halar_3695	ENOG4105D7Z	glutathione synthase
Halar_3697	ENOG4105BZA	Phosphoglycerate kinase
Halar_3704	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
Halar_3717	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Halar_3720	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Halar_3721	ENOG4108JQ7	(ABC) transporter
Halar_3722	ENOG4105C3U	ABC transporter
Halar_3723	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Halar_3725	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
Halar_3730	ENOG4105CXK	mandelate racemase muconate lactonizing
Halar_3731	ENOG4105EDK	PfkB domain protein
Halar_3732	ENOG4105IU0	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Halar_3736	ENOG4106PMH	Extracellular solute-binding protein family 3